pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6536-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 3,000 1,089E-07 2,006E-04 ! positive regulation of hormone secretion GO:0046887 11 11 3,000 2,828E-07 2,606E-04 ! negative regulation of lymphocyte activation GO:0051250 11 11 3,000 2,828E-07 1,737E-04 ! negative regulation of hormone secretion GO:0046888 13 13 3,000 6,078E-07 2,8E-04 ! negative regulation of leukocyte activation GO:0002695 13 13 3,000 6,078E-07 2,24E-04 ! ovarian follicle development GO:0001541 15 15 3,000 1,151E-06 3,535E-04 ! negative regulation of cell activation GO:0050866 15 15 3,000 1,151E-06 3,03E-04 ! hemoglobin biosynthetic process GO:0042541 5 5 2,000 1,671E-06 3,85E-04 ! cellular glucose homeostasis GO:0001678 5 5 2,000 1,671E-06 3,422E-04 ! negative regulation of protein kinase activity GO:0006469 37 37 4,000 1,714E-06 3,16E-04 ! negative regulation of kinase activity GO:0033673 38 38 4,000 1,966E-06 3,294E-04 ! positive regulation of transport GO:0051050 71 70 5,000 2,235E-06 3,432E-04 ! negative regulation of transferase activity GO:0051348 40 40 4,000 2,556E-06 3,624E-04 ! reproductive structure development GO:0048608 43 43 4,000 3,693E-06 4,862E-04 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 2,000 5,804E-06 7,131E-04 ! hemoglobin metabolic process GO:0020027 7 7 2,000 5,804E-06 6,685E-04 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 2,000 5,804E-06 6,292E-04 ! regulation of macrophage differentiation GO:0045649 8 7 2,000 5,804E-06 5,942E-04 ! ovulation cycle process GO:0022602 22 22 3,000 5,994E-06 5,814E-04 ! regulation of hormone secretion GO:0046883 23 23 3,000 7,226E-06 6,659E-04 ! female gonad development GO:0008585 23 23 3,000 7,226E-06 6,342E-04 ! glucose homeostasis GO:0042593 24 24 3,000 8,636E-06 7,235E-04 GO:0033500|carbohydrate homeostasis, ! ovulation cycle GO:0042698 24 24 3,000 8,636E-06 6,92E-04 ! negative regulation of secretion GO:0051048 26 25 3,000 1,024E-05 7,863E-04 ! development of primary female sexual characteristics GO:0046545 25 25 3,000 1,024E-05 7,548E-04 GO:0046660|female sex differentiation, ! negative regulation of immune system process GO:0002683 25 25 3,000 1,024E-05 7,258E-04 ! reproductive developmental process GO:0003006 56 56 4,000 1,389E-05 9,481E-04 ! regulation of B cell differentiation GO:0045577 10 10 2,000 1,967E-05 1,294E-03 ! activation of MAPKK activity GO:0000186 12 11 2,000 2,693E-05 1,712E-03 ! regulation of lymphocyte differentiation GO:0045619 32 32 3,000 2,829E-05 1,738E-03 ! regulation of cytokine biosynthetic process GO:0042035 35 35 3,000 4,069E-05 2,419E-03 ! multicellular organism reproduction GO:0032504 36 35 3,000 4,069E-05 2,343E-03 GO:0048609|reproductive process in a multicellular organism, ! gonad development GO:0008406 36 36 3,000 4,559E-05 2,546E-03 ! negative regulation of phosphorylation GO:0042326 13 13 2,000 4,632E-05 2,511E-03 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 2,000 4,632E-05 2,439E-03 ! positive regulation of secretion GO:0051047 39 38 3,000 5,667E-05 2,901E-03 ! regulation of interferon-gamma production GO:0032649 14 14 2,000 5,872E-05 2,925E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 5,872E-05 2,848E-03 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 2,000 5,872E-05 2,775E-03 GO:0045936|negative regulation of phosphate metabolic process, ! response to starvation GO:0042594 15 15 2,000 7,311E-05 3,369E-03 ! development of primary sexual characteristics GO:0045137 42 42 3,000 8,454E-05 3,8E-03 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 2,000 8,963E-05 3,933E-03 ! regulation of cellular localization GO:0060341 86 85 4,000 1,058E-04 4,535E-03 ! positive regulation of protein kinase activity GO:0045860 89 86 4,000 1,119E-04 4,686E-03 ! positive regulation of transferase activity GO:0051347 91 88 4,000 1,248E-04 5,112E-03 GO:0033674|positive regulation of kinase activity, ! sex differentiation GO:0007548 47 47 3,000 1,32E-04 5,289E-03 ! rhythmic process GO:0048511 47 47 3,000 1,32E-04 5,176E-03 ! negative regulation of cell cycle GO:0045786 92 91 4,000 1,463E-04 5,619E-03 ! negative regulation of transport GO:0051051 51 50 3,000 1,684E-04 6,333E-03 ! regulation of B cell activation GO:0050864 20 20 2,000 1,796E-04 6,621E-03 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 2,000 2,087E-04 7,543E-03 ! Notch signaling pathway GO:0007219 22 21 2,000 2,087E-04 7,398E-03 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 3,098E-04 0,0107722 ! prostate gland development GO:0030850 5 5 1,000 3,098E-04 0,01057272 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 1,000 3,098E-04 0,01038049 ! amyloid precursor protein catabolic process GO:0042987 5 5 1,000 3,098E-04 0,01019512 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 3,098E-04 0,01001626 ! temperature homeostasis GO:0001659 5 5 1,000 3,098E-04 9,844E-03 ! peptidyl-histidine modification GO:0018202 5 5 1,000 3,098E-04 9,677E-03 ! positive regulation of erythrocyte differentiation GO:0045648 5 5 1,000 3,098E-04 9,515E-03 ! musculoskeletal movement GO:0050881 5 5 1,000 3,098E-04 9,359E-03 GO:0050879|multicellular organismal movement, ! sarcomere organization GO:0045214 5 5 1,000 3,098E-04 9,208E-03 ! regulation of fatty acid oxidation GO:0046320 5 5 1,000 3,098E-04 9,062E-03 ! blastocyst formation GO:0001825 5 5 1,000 3,098E-04 8,921E-03 ! regulation of lymphocyte activation GO:0051249 62 62 3,000 3,884E-04 0,01101229 ! regulation of secretion GO:0051046 65 63 3,000 4,13E-04 0,01153371 ! positive regulation of cell growth GO:0030307 6 6 1,000 4,63E-04 0,01273615 ! ER overload response GO:0006983 6 6 1,000 4,63E-04 0,01254885 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 4,63E-04 0,01236699 GO:0070667|negative regulation of mast cell proliferation, ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 4,63E-04 0,01219032 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 4,63E-04 0,01201862 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 4,63E-04 0,0118517 ! negative regulation of BMP signaling pathway GO:0030514 6 6 1,000 4,63E-04 0,01168934 ! localization within membrane GO:0051668 6 6 1,000 4,63E-04 0,01153138 ! protein amino acid autophosphorylation GO:0046777 28 28 2,000 5,002E-04 0,0122927 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 5,558E-04 0,01347776 ! regulation of leukocyte activation GO:0002694 69 69 3,000 5,85E-04 0,01400199 ! keratinocyte proliferation GO:0043616 7 7 1,000 6,459E-04 0,01526118 ! amyloid precursor protein metabolic process GO:0042982 7 7 1,000 6,459E-04 0,015068 ! positive regulation of lipid metabolic process GO:0045834 7 7 1,000 6,459E-04 0,01487965 ! regulation of mRNA processing GO:0050684 7 7 1,000 6,459E-04 0,01469596 ! membrane protein ectodomain proteolysis GO:0006509 7 7 1,000 6,459E-04 0,01451674 GO:0033619|membrane protein proteolysis, ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 6,459E-04 0,01434184 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 1,000 6,459E-04 0,0141711 ! myofibril assembly GO:0030239 7 7 1,000 6,459E-04 0,01400438 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 6,459E-04 0,01384154 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of T cell activation GO:0050868 7 7 1,000 6,459E-04 0,01368244 ! regulation of cell activation GO:0050865 71 71 3,000 6,522E-04 0,01365855 ! regulation of myeloid cell differentiation GO:0045637 32 31 2,000 6,784E-04 0,01404751 ! regulation of cytokine production GO:0001817 72 72 3,000 6,877E-04 0,01408325 ! activation of protein kinase activity GO:0032147 35 33 2,000 8,17E-04 0,0165459 ! cardiac muscle contraction GO:0060048 8 8 1,000 8,581E-04 0,01719001 ! muscle cell development GO:0055001 8 8 1,000 8,581E-04 0,01700517 ! regulation of fatty acid metabolic process GO:0019217 8 8 1,000 8,581E-04 0,01682426 ! negative regulation of blood coagulation GO:0030195 9 8 1,000 8,581E-04 0,01664717 ! peptidyl-serine modification GO:0018209 8 8 1,000 8,581E-04 0,01647376 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 8,581E-04 0,01630393 ! regulation of angiogenesis GO:0045765 35 34 2,000 8,925E-04 0,01678503 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 9,724E-04 0,01810218 ! MAPKKK cascade GO:0000165 82 81 3,000 1,072E-03 0,01976156 ! positive regulation of cell size GO:0045793 9 9 1,000 1,099E-03 0,02005995 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 1,099E-03 0,01986329 ! negative regulation of caspase activity GO:0043154 9 9 1,000 1,099E-03 0,01967044 ! chromosome segregation GO:0007059 38 38 2,000 1,239E-03 0,02195129 ! axon guidance GO:0007411 39 38 2,000 1,239E-03 0,02174223 ! positive regulation of cell motion GO:0051272 39 39 2,000 1,337E-03 0,02324076 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 1,369E-03 0,02358419 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 1,369E-03 0,02336582 ! fat cell differentiation GO:0045444 10 10 1,000 1,369E-03 0,02315145 ! neuromuscular junction development GO:0007528 10 10 1,000 1,369E-03 0,02294099 ! regulation of erythrocyte differentiation GO:0045646 10 10 1,000 1,369E-03 0,02273431 ! regulation of BMP signaling pathway GO:0030510 10 10 1,000 1,369E-03 0,02253132 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 1,000 1,369E-03 0,02233193 ! negative regulation of coagulation GO:0050819 11 10 1,000 1,369E-03 0,02213604 ! protein stabilization GO:0050821 10 10 1,000 1,369E-03 0,02194355 ! skin development GO:0043588 11 11 1,000 1,668E-03 0,0264936 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 1,000 1,668E-03 0,02626716 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 1,668E-03 0,02604455 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 1,000 1,668E-03 0,02582569 GO:0003015|heart process, ! regulation of transmembrane transporter activity GO:0022898 11 11 1,000 1,668E-03 0,02561048 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! cellular response to starvation GO:0009267 11 11 1,000 1,668E-03 0,02539882 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 1,668E-03 0,02519063 ! regulation of cellular ketone metabolic process GO:0010565 11 11 1,000 1,668E-03 0,02498583 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 1,000 1,668E-03 0,02478433 GO:0060415|muscle tissue morphogenesis, ! regulation of monooxygenase activity GO:0032768 11 11 1,000 1,668E-03 0,02458606 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 1,668E-03 0,02439093 GO:0006109|regulation of carbohydrate metabolic process, ! mitochondrion organization GO:0007005 44 43 2,000 1,777E-03 0,02578752 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 2,000 1,9E-03 0,02735107 ! protein amino acid ADP-ribosylation GO:0006471 12 12 1,000 1,994E-03 0,02848623 ! negative regulation of peptidase activity GO:0010466 12 12 1,000 1,994E-03 0,0282671 ! actomyosin structure organization GO:0031032 12 12 1,000 1,994E-03 0,02805132 ! positive regulation of endocytosis GO:0045807 12 12 1,000 1,994E-03 0,02783881 ! glycoprotein catabolic process GO:0006516 13 12 1,000 1,994E-03 0,0276295 ! regulation of chromosome organization GO:0033044 12 12 1,000 1,994E-03 0,02742331 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 2,000 2,027E-03 0,02767681 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 2,000 2,16E-03 0,0292754 ! positive regulation of ligase activity GO:0051351 47 46 2,000 2,16E-03 0,02906171 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 2,348E-03 0,03135749 ! actin filament bundle formation GO:0051017 13 13 1,000 2,348E-03 0,0311319 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 2,348E-03 0,03090953 ! blastocyst development GO:0001824 13 13 1,000 2,348E-03 0,03069031 ! actin filament organization GO:0007015 50 48 2,000 2,442E-03 0,03169811 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 2,000 2,442E-03 0,03147645 ! gland development GO:0048732 51 49 2,000 2,591E-03 0,0331666 ! cell cycle arrest GO:0007050 49 49 2,000 2,591E-03 0,03293786 ! positive regulation of MAP kinase activity GO:0043406 50 49 2,000 2,591E-03 0,03271226 ! regulation of ligase activity GO:0051340 50 49 2,000 2,591E-03 0,03248973 ! regulation of blood coagulation GO:0030193 15 14 1,000 2,73E-03 0,03398999 ! interphase of mitotic cell cycle GO:0051329 52 51 2,000 2,906E-03 0,03594893 GO:0051325|interphase, ! striated muscle cell differentiation GO:0051146 16 15 1,000 3,138E-03 0,03855809 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 3,138E-03 0,03830274 ! response to mechanical stimulus GO:0009612 15 15 1,000 3,138E-03 0,03805075 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 1,000 3,138E-03 0,03780205 ! regulation of synaptic plasticity GO:0048167 16 16 1,000 3,574E-03 0,04276857 ! cellular response to nutrient levels GO:0031669 16 16 1,000 3,574E-03 0,04249264 ! regulation of coagulation GO:0050818 17 16 1,000 3,574E-03 0,04222025 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 4,036E-03 0,04737516 ! myelination GO:0042552 17 17 1,000 4,036E-03 0,04707531 ! regulation of transmembrane transport GO:0034762 17 17 1,000 4,036E-03 0,04677924 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 1,000 4,036E-03 0,04648687 ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 4,036E-03 0,04619813 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 4,398E-03 0,05002856 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 4,524E-03 0,05115204 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 4,524E-03 0,05084014 ! striated muscle contraction GO:0006941 18 18 1,000 4,524E-03 0,05053202 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 4,524E-03 0,05022761 ! ensheathment of neurons GO:0007272 18 18 1,000 4,524E-03 0,04992685 GO:0008366|axon ensheathment, ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 1,000 5,038E-03 0,05527062 ! peripheral nervous system development GO:0007422 19 19 1,000 5,038E-03 0,05494357 ! regulation of protein stability GO:0031647 19 19 1,000 5,038E-03 0,05462037 ! axonogenesis GO:0007409 66 62 2,000 5,056E-03 0,05449734 ! detection of abiotic stimulus GO:0009582 21 20 1,000 5,578E-03 0,05976976 ! positive regulation of cellular component organization GO:0051130 65 65 2,000 5,772E-03 0,06149071 ! regulation of MAP kinase activity GO:0043405 67 66 2,000 6,023E-03 0,06379961 ! mRNA catabolic process GO:0006402 21 21 1,000 6,143E-03 0,06469743 ! mammary gland development GO:0030879 23 21 1,000 6,143E-03 0,06432983 ! regulation of action potential in neuron GO:0019228 21 21 1,000 6,143E-03 0,06396638 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 6,143E-03 0,06360702 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 2,000 6,281E-03 0,0646722 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! striated muscle tissue development GO:0014706 69 67 2,000 6,281E-03 0,06431291 ! negative regulation of cell differentiation GO:0045596 68 67 2,000 6,281E-03 0,06395759 ! regulation of cell size GO:0008361 68 68 2,000 6,546E-03 0,06628324 ! erythrocyte differentiation GO:0030218 23 22 1,000 6,734E-03 0,06781357 ! detection of external stimulus GO:0009581 23 22 1,000 6,734E-03 0,06744502 ! response to nutrient levels GO:0031667 69 69 2,000 6,817E-03 0,06790749 ! cell part morphogenesis GO:0032990 75 70 2,000 7,094E-03 0,07029252 ! wound healing GO:0042060 74 70 2,000 7,094E-03 0,06991662 ! growth GO:0040007 70 70 2,000 7,094E-03 0,06954473 ! muscle tissue development GO:0060537 72 70 2,000 7,094E-03 0,06917677 ! epithelial cell differentiation GO:0030855 23 23 1,000 7,349E-03 0,07128089 ! positive regulation of growth GO:0045927 23 23 1,000 7,349E-03 0,07090769 ! calcium-mediated signaling GO:0019722 23 23 1,000 7,349E-03 0,07053838 ! response to extracellular stimulus GO:0009991 72 72 2,000 7,669E-03 0,07323477 ! erythrocyte homeostasis GO:0034101 25 24 1,000 7,988E-03 0,07588652 ! androgen receptor signaling pathway GO:0030521 24 24 1,000 7,988E-03 0,07549735 ! glucan metabolic process GO:0044042 25 24 1,000 7,988E-03 0,07511216 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of action potential GO:0001508 24 24 1,000 7,988E-03 0,07473088 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 8,652E-03 0,08053134 ! regulation of T cell proliferation GO:0042129 25 25 1,000 8,652E-03 0,08012666 ! heart morphogenesis GO:0003007 25 25 1,000 8,652E-03 0,07972603 ! regulation of endocytosis GO:0030100 25 25 1,000 8,652E-03 0,07932938 ! cell morphogenesis involved in differentiation GO:0000904 82 77 2,000 9,225E-03 0,08416945 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 1,000 9,339E-03 0,08479072 ! synapse organization GO:0050808 26 26 1,000 9,339E-03 0,08437508 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 9,339E-03 0,0839635 ! regulation of T cell differentiation GO:0045580 26 26 1,000 9,339E-03 0,08355591 ! regulation of protein modification process GO:0031399 79 78 2,000 9,557E-03 0,08509041 ! regulation of cell motion GO:0051270 79 79 2,000 9,896E-03 0,08768256 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 0,01005068 0,08862874 ! energy reserve metabolic process GO:0006112 28 27 1,000 0,01005068 0,0882067 ! neuron projection development GO:0031175 85 80 2,000 0,01024148 0,08945523 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 1,000 0,01078533 0,09376115 GO:0007254|JNK cascade, ! keratinocyte differentiation GO:0030216 28 28 1,000 0,01078533 0,09332096 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,01078533 0,09288488 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 0,01154307 0,09894831 ! positive regulation of protein transport GO:0051222 29 29 1,000 0,01154307 0,09849022 ! response to UV GO:0009411 29 29 1,000 0,01154307 0,09803634 ! positive regulation of cell cycle GO:0045787 29 29 1,000 0,01154307 0,09758664 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,01154307 0,09714103 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! RNA catabolic process GO:0006401 30 30 1,000 0,01232364 0,10323852 ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,01232364 0,10277137 GO:0010863|positive regulation of phospholipase C activity, ! regulation of anatomical structure morphogenesis GO:0022603 90 86 2,000 0,01246317 0,10346675 ! heart development GO:0007507 90 87 2,000 0,01285828 0,10626821 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,01312677 0,10800281 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,01312677 0,10752279 ! digestion GO:0007586 31 31 1,000 0,01312677 0,10704703 ! regulation of intracellular transport GO:0032386 31 31 1,000 0,01312677 0,10657546 ! epidermal cell differentiation GO:0009913 31 31 1,000 0,01312677 0,10610802 ! negative regulation of cell motion GO:0051271 31 31 1,000 0,01312677 0,10564467 ! negative regulation of cell growth GO:0030308 32 32 1,000 0,01395218 0,11179939 ! muscle fiber development GO:0048747 32 32 1,000 0,01395218 0,11131541 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,01395218 0,1108356 ! regulation of vesicle-mediated transport GO:0060627 33 32 1,000 0,01395218 0,11035991 ! cell maturation GO:0048469 32 32 1,000 0,01395218 0,10988829 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,01395218 0,10942068 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 0,01395218 0,10895703 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,01395218 0,1084973 ! protein maturation by peptide bond cleavage GO:0051605 32 32 1,000 0,01395218 0,10804142 ! negative regulation of cell size GO:0045792 33 33 1,000 0,01479961 0,11412417 ! regulation of neuron differentiation GO:0045664 34 33 1,000 0,01479961 0,11364866 ! regulation of synaptic transmission GO:0050804 33 33 1,000 0,01479961 0,11317708 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 2,000 0,01494153 0,11379022 ! tissue morphogenesis GO:0048729 94 93 2,000 0,01537984 0,11664625 ! muscle cell differentiation GO:0042692 35 34 1,000 0,0156688 0,11835081 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 0,0156688 0,11786775 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 0,0156688 0,11738861 ! detection of stimulus GO:0051606 36 34 1,000 0,0156688 0,11691336 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,01655949 0,12306106 ! regulation of cell growth GO:0001558 97 96 2,000 0,01673836 0,12389079 ! positive regulation of cell migration GO:0030335 36 36 1,000 0,01747142 0,12879934 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,01747142 0,12828619 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,01747142 0,12777712 ! regulation of transmission of nerve impulse GO:0051969 36 36 1,000 0,01747142 0,12727207 ! regulation of lipase activity GO:0060191 36 36 1,000 0,01747142 0,126771 ! coagulation GO:0050817 39 36 1,000 0,01747142 0,12627386 GO:0007596|blood coagulation, ! lung development GO:0030324 38 37 1,000 0,01840434 0,13249687 ! negative regulation of growth GO:0045926 37 37 1,000 0,01840434 0,13198132 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,01840434 0,13146976 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 0,01840434 0,13096216 ! muscle organ development GO:0007517 102 100 2,000 0,01865192 0,13221345 ! urogenital system development GO:0001655 38 38 1,000 0,01935799 0,1366926 ! regulation of neurological system process GO:0031644 38 38 1,000 0,01935799 0,13617088 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 0,01935799 0,13565312 ! regulation of homeostatic process GO:0032844 38 38 1,000 0,01935799 0,13513928 ! hemostasis GO:0007599 42 39 1,000 0,02033211 0,14140408 ! positive regulation of protein modification process GO:0031401 39 39 1,000 0,02033211 0,14087248 ! respiratory tube development GO:0030323 40 39 1,000 0,02033211 0,14034487 ! respiratory system development GO:0060541 40 39 1,000 0,02033211 0,13982119 ! developmental maturation GO:0021700 39 39 1,000 0,02033211 0,13930141 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 0,02132646 0,14557285 ! myeloid cell differentiation GO:0030099 42 40 1,000 0,02132646 0,14503568 ! regulation of caspase activity GO:0043281 41 41 1,000 0,02234079 0,1513753 ! respiratory electron transport chain GO:0022904 43 42 1,000 0,02337486 0,1578017 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,02337486 0,15722578 ! negative regulation of ligase activity GO:0051352 43 42 1,000 0,02337486 0,15665405 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,02337486 0,15608646 ! homeostasis of number of cells GO:0048872 44 43 1,000 0,02442841 0,16253272 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,02659302 0,17629834 ! Wnt receptor signaling pathway GO:0016055 46 45 1,000 0,02659302 0,17566645 ! protein processing GO:0016485 45 45 1,000 0,02659302 0,17503907 ! tube morphogenesis GO:0035239 47 46 1,000 0,0277036 0,18170012 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,0277036 0,1810558 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 1,000 0,0277036 0,18041602 ! regulation of membrane potential GO:0042391 46 46 1,000 0,0277036 0,17978075 ! rRNA transcription GO:0009303 5 5 0,000 0,02803157 0,1812708 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,02803157 0,18063698 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,02803157 0,18000758 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,02803157 0,17938256 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,02803157 0,17876186 ! reproductive cellular process GO:0048610 5 5 0,000 0,02803157 0,17814544 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,02803157 0,17753325 ! metencephalon development GO:0022037 5 5 0,000 0,02803157 0,17692526 ! water transport GO:0006833 5 5 0,000 0,02803157 0,17632142 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,02803157 0,17572169 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,02803157 0,17512602 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,02803157 0,17453438 ! glycerol metabolic process GO:0006071 5 5 0,000 0,02803157 0,17394672 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,02803157 0,17336301 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,02803157 0,1727832 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,02803157 0,17220726 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,02803157 0,17163514 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,02803157 0,17106681 ! filopodium assembly GO:0046847 7 5 0,000 0,02803157 0,17050223 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,02803157 0,16994137 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,02803157 0,16938419 ! GTP metabolic process GO:0046039 5 5 0,000 0,02803157 0,16883064 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,02803157 0,16828071 ! mRNA stabilization GO:0048255 5 5 0,000 0,02803157 0,16773434 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,02803157 0,16719151 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,02803157 0,16665218 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,02803157 0,16611632 ! social behavior GO:0035176 5 5 0,000 0,02803157 0,1655839 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,02803157 0,16505488 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,02803157 0,16452923 ! memory GO:0007613 5 5 0,000 0,02803157 0,16400691 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,02803157 0,1634879 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,02803157 0,16297217 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,02803157 0,16245968 ! response to lipid GO:0033993 5 5 0,000 0,02803157 0,1619504 ! erythrocyte maturation GO:0043249 5 5 0,000 0,02803157 0,1614443 ! hippocampus development GO:0021766 6 5 0,000 0,02803157 0,16094136 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,02803157 0,16044154 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,02803157 0,15994482 ! mechanosensory behavior GO:0007638 5 5 0,000 0,02803157 0,15945116 ! heart looping GO:0001947 5 5 0,000 0,02803157 0,15896054 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,02803157 0,15847293 ! response to interferon-gamma GO:0034341 5 5 0,000 0,02803157 0,15798831 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,02803157 0,15750664 ! endocrine pancreas development GO:0031018 5 5 0,000 0,02803157 0,15702789 ! pH reduction GO:0045851 5 5 0,000 0,02803157 0,15655205 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,02803157 0,15607908 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,02803157 0,15560897 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,02803157 0,15514167 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,02803157 0,15467718 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,02803157 0,15421545 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,02803157 0,15375648 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,02803157 0,15330023 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,02803157 0,15284668 ! adrenal gland development GO:0030325 5 5 0,000 0,02803157 0,1523958 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,02803157 0,15194758 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,02803157 0,15150198 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,02803157 0,151059 ! astrocyte differentiation GO:0048708 5 5 0,000 0,02803157 0,15061859 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,02803157 0,15018075 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,02803157 0,14974544 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,02803157 0,14931265 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,02803157 0,14888235 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,02803157 0,14845453 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,02803157 0,14802916 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,02803157 0,14760622 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,02803157 0,14718569 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,02803157 0,14676755 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,02803157 0,14635178 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,02803157 0,14593835 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,02803157 0,14552726 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,02803157 0,14511847 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,02803157 0,14471198 ! response to ATP GO:0033198 5 5 0,000 0,02803157 0,14430776 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,02803157 0,14390578 ! regulation of appetite GO:0032098 5 5 0,000 0,02803157 0,14350605 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,02803157 0,14310852 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,02803157 0,1427132 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,02803157 0,14232005 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,02803157 0,14192906 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02803157 0,14154021 ! receptor clustering GO:0043113 5 5 0,000 0,02803157 0,14115349 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,02803157 0,14076887 ! fear response GO:0042596 5 5 0,000 0,02803157 0,14038635 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,02803157 0,1400059 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,02803157 0,1396275 ! retinol metabolic process GO:0042572 5 5 0,000 0,02803157 0,13925115 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,02803157 0,13887682 GO:0042921|glucocorticoid receptor signaling pathway, ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,02803157 0,1385045 ! parturition GO:0007567 5 5 0,000 0,02803157 0,13813416 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,02803157 0,1377658 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,02803157 0,13739941 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,02803157 0,13703495 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,02803157 0,13667243 ! protein heterooligomerization GO:0051291 5 5 0,000 0,02803157 0,13631181 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,02803157 0,1359531 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,02803157 0,13559626 ! response to UV-B GO:0010224 5 5 0,000 0,02803157 0,1352413 ! oligodendrocyte development GO:0014003 5 5 0,000 0,02803157 0,13488819 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,02803157 0,13453692 ! activated T cell proliferation GO:0050798 5 5 0,000 0,02803157 0,13418747 ! interaction with symbiont GO:0051702 5 5 0,000 0,02803157 0,13383984 ! cellular extravasation GO:0045123 5 5 0,000 0,02803157 0,133494 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,02803157 0,13314994 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,02803157 0,13280765 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,02803157 0,13246712 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,02803157 0,13212833 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,02803157 0,13179127 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,02803157 0,13145592 ! response to amine stimulus GO:0014075 5 5 0,000 0,02803157 0,13112228 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,02803157 0,13079032 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,02803157 0,13046004 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,02803157 0,13013143 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,02803157 0,12980446 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,02803157 0,12947914 ! neuron recognition GO:0008038 5 5 0,000 0,02803157 0,12915544 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,02803157 0,12883336 ! decidualization GO:0046697 5 5 0,000 0,02803157 0,12851288 ! hair follicle maturation GO:0048820 5 5 0,000 0,02803157 0,12819399 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,02803157 0,12787668 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,02803157 0,12756093 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,02803157 0,12724674 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,02803157 0,1269341 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,02803157 0,12662298 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,02803157 0,12631339 ! postreplication repair GO:0006301 5 5 0,000 0,02803157 0,12600531 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,02803157 0,12569873 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,02803157 0,12539363 ! histone methylation GO:0016571 5 5 0,000 0,02803157 0,12509002 ! DNA methylation GO:0006306 5 5 0,000 0,02803157 0,12478787 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02803157 0,12448717 ! T cell lineage commitment GO:0002360 5 5 0,000 0,02803157 0,12418792 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,02803157 0,12389011 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,02803157 0,12359372 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,02803157 0,12329875 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,02803157 0,12300518 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,02803157 0,12271301 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,02803157 0,12242222 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,02803157 0,12213281 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,02803157 0,12184476 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,02803157 0,12155806 ! sterol catabolic process GO:0016127 5 5 0,000 0,02803157 0,12127272 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,02803157 0,1209887 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,02803157 0,12070602 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,02803157 0,12042465 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,02803157 0,1201446 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,02803157 0,11986584 ! zymogen activation GO:0031638 5 5 0,000 0,02803157 0,11958837 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,02803157 0,11931219 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,02803157 0,11903727 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,02803157 0,11876362 ! peptidyl-lysine modification GO:0018205 5 5 0,000 0,02803157 0,11849123 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,02803157 0,11822008 ! nucleosome positioning GO:0016584 5 5 0,000 0,02803157 0,11795018 ! regulation of isotype switching GO:0045191 5 5 0,000 0,02803157 0,1176815 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,02803157 0,11741404 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,02803157 0,11714779 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,02803157 0,11688275 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,02803157 0,11661891 ! NADPH regeneration GO:0006740 5 5 0,000 0,02803157 0,11635625 GO:0006098|pentose-phosphate shunt, ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,02803157 0,11609478 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,02803157 0,11583448 GO:0002688|regulation of leukocyte chemotaxis, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,02803157 0,11557534 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,02803157 0,11531736 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,02803157 0,11506053 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,02803157 0,11480484 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,02803157 0,11455028 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,02803157 0,11429685 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,02803157 0,11404454 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,02803157 0,11379334 ! spleen development GO:0048536 5 5 0,000 0,02803157 0,11354325 ! male genitalia development GO:0030539 5 5 0,000 0,02803157 0,11329425 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,02803157 0,11304634 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,02803157 0,11279951 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,02803157 0,11255376 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,02803157 0,11230908 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,02803157 0,11206546 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,02803157 0,11182289 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,02803157 0,11158138 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,02803157 0,1113409 ! ATP catabolic process GO:0006200 5 5 0,000 0,02803157 0,11110146 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02803157 0,11086304 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,02803157 0,11062565 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,02803157 0,11038927 ! embryonic gut development GO:0048566 5 5 0,000 0,02803157 0,11015389 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,02803157 0,10991952 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,02803157 0,10968615 ! activation of innate immune response GO:0002218 5 5 0,000 0,02803157 0,10945376 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,02803157 0,10922236 ! catecholamine transport GO:0051937 5 5 0,000 0,02803157 0,10899193 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,02803157 0,10876248 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,02803157 0,10853398 ! muscle adaptation GO:0043500 5 5 0,000 0,02803157 0,10830645 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,02803157 0,10807987 ! embryonic heart tube development GO:0035050 5 5 0,000 0,02803157 0,10785423 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,02803157 0,10762953 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,02803157 0,10740577 ! defense response to fungus GO:0050832 5 5 0,000 0,02803157 0,10718294 ! lysogeny GO:0030069 5 5 0,000 0,02803157 0,10696103 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,02803157 0,10674003 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,02803157 0,10651995 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,02803157 0,10630078 ! response to nicotine GO:0035094 5 5 0,000 0,02803157 0,1060825 ! establishment of cell polarity GO:0030010 5 5 0,000 0,02803157 0,10586512 ! mitochondrion localization GO:0051646 5 5 0,000 0,02803157 0,10564862 ! nucleus localization GO:0051647 5 5 0,000 0,02803157 0,10543301 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,02803157 0,10521828 ! ossification GO:0001503 50 49 1,000 0,0311456 0,11666938 GO:0060348|bone development, ! skeletal muscle tissue development GO:0007519 50 49 1,000 0,0311456 0,11643273 GO:0060538|skeletal muscle organ development, ! regulation of neurogenesis GO:0050767 51 50 1,000 0,03232891 0,1206117 ! transcription initiation GO:0006352 50 50 1,000 0,03232891 0,12036804 ! protein maturation GO:0051604 51 51 1,000 0,03352983 0,12458766 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,03354528 0,12439426 ! axon extension GO:0048675 7 6 0,000 0,03354528 0,12414447 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,03354528 0,12389569 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 0,03354528 0,1236479 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 0,03354528 0,12340109 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,03354528 0,12315527 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,03354528 0,12291043 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,03354528 0,12266656 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,03354528 0,12242366 ! virus-host interaction GO:0019048 6 6 0,000 0,03354528 0,12218171 ! regulation of S phase GO:0033261 6 6 0,000 0,03354528 0,12194073 ! myotube differentiation GO:0014902 6 6 0,000 0,03354528 0,12170068 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,03354528 0,12146159 ! bone remodeling GO:0046849 6 6 0,000 0,03354528 0,12122343 ! N-glycan processing GO:0006491 6 6 0,000 0,03354528 0,1209862 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,03354528 0,1207499 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,03354528 0,12051452 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,03354528 0,12028005 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,03354528 0,1200465 ! RNA methylation GO:0001510 6 6 0,000 0,03354528 0,11981385 ! cartilage condensation GO:0001502 7 6 0,000 0,03354528 0,1195821 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,03354528 0,11935125 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,03354528 0,11912129 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,03354528 0,11889221 ! artery development GO:0060840 6 6 0,000 0,03354528 0,11866401 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,03354528 0,11843668 ! bile acid metabolic process GO:0008206 6 6 0,000 0,03354528 0,11821022 ! androgen metabolic process GO:0008209 6 6 0,000 0,03354528 0,11798463 ! estrogen metabolic process GO:0008210 6 6 0,000 0,03354528 0,1177599 ! limbic system development GO:0021761 7 6 0,000 0,03354528 0,11753602 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,03354528 0,11731299 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,03354528 0,11709081 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,03354528 0,11686947 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,03354528 0,11664896 ! pathogenesis GO:0009405 6 6 0,000 0,03354528 0,11642928 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,03354528 0,11621043 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,03354528 0,1159924 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,03354528 0,11577518 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,03354528 0,11555878 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,03354528 0,11534319 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,03354528 0,11512839 ! arginine metabolic process GO:0006525 6 6 0,000 0,03354528 0,1149144 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,03354528 0,1147012 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,03354528 0,11448879 ! glutamate catabolic process GO:0006538 7 6 0,000 0,03354528 0,11427717 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,03354528 0,11406632 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,03354528 0,11385626 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,03354528 0,11364696 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,03354528 0,11343844 ! V(D)J recombination GO:0033151 6 6 0,000 0,03354528 0,11323067 ! focal adhesion formation GO:0048041 7 6 0,000 0,03354528 0,11302367 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,03354528 0,11281742 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,03354528 0,11261193 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,03354528 0,11240718 ! regulation of heart rate GO:0002027 6 6 0,000 0,03354528 0,11220317 ! lipid digestion GO:0044241 6 6 0,000 0,03354528 0,11199991 ! asymmetric protein localization GO:0008105 6 6 0,000 0,03354528 0,11179737 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,03354528 0,11159557 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,03354528 0,1113945 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,03354528 0,11119415 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,03354528 0,11099452 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,03354528 0,11079561 ! ruffle organization GO:0031529 6 6 0,000 0,03354528 0,1105974 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,03354528 0,11039991 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,03354528 0,11020312 ! neutral amino acid transport GO:0015804 6 6 0,000 0,03354528 0,11000702 ! L-amino acid transport GO:0015807 6 6 0,000 0,03354528 0,10981163 ! bone mineralization GO:0030282 6 6 0,000 0,03354528 0,10961693 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,03354528 0,10942292 ! negative regulation of ossification GO:0030279 6 6 0,000 0,03354528 0,10922959 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,03354528 0,10903694 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,03354528 0,10884498 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,03354528 0,10865369 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,03354528 0,10846307 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,03354528 0,10827311 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,03354528 0,10808382 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,03354528 0,1078952 ! regulation of organ growth GO:0046620 6 6 0,000 0,03354528 0,10770723 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,03354528 0,10751991 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,03354528 0,10733324 ! response to dsRNA GO:0043331 6 6 0,000 0,03354528 0,10714722 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,03354528 0,10696185 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,03354528 0,10677711 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,03354528 0,10659301 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,03354528 0,10640955 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,03354528 0,10622671 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,03354528 0,10604451 ! multicellular organismal aging GO:0010259 6 6 0,000 0,03354528 0,10586292 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,03354528 0,10568196 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,03354528 0,10550162 ! erythrocyte development GO:0048821 6 6 0,000 0,03354528 0,10532189 ! renal water homeostasis GO:0003091 6 6 0,000 0,03354528 0,10514277 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,03354528 0,10496426 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,03354528 0,10478635 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,03354528 0,10460905 ! ribosome assembly GO:0042255 6 6 0,000 0,03354528 0,10443234 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,03354528 0,10425624 ! diencephalon development GO:0021536 6 6 0,000 0,03354528 0,10408072 ! fucose catabolic process GO:0019317 6 6 0,000 0,03354528 0,10390579 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,03354528 0,10373146 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,03354528 0,1035577 ! regulation of lipid transport GO:0032368 6 6 0,000 0,03354528 0,10338453 ! regulation of cell division GO:0051302 6 6 0,000 0,03354528 0,10321193 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,03354528 0,10303991 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,03354528 0,10286847 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,03354528 0,10269759 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,03354528 0,10252728 ! neuroblast proliferation GO:0007405 6 6 0,000 0,03354528 0,10235753 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,03354528 0,10218834 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,03354528 0,10201972 ! regulation of glucose transport GO:0010827 6 6 0,000 0,03354528 0,10185164 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,03354528 0,10168412 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,03354528 0,10151716 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,03354528 0,10135073 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,03354528 0,10118486 ! thymus development GO:0048538 6 6 0,000 0,03354528 0,10101952 ! lymph node development GO:0048535 6 6 0,000 0,03354528 0,10085473 ! organic cation transport GO:0015695 6 6 0,000 0,03354528 0,10069047 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,03354528 0,10052674 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,03354528 0,10036355 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,03354528 0,10020089 ! sperm-egg recognition GO:0035036 7 6 0,000 0,03354528 0,10003875 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,03354528 0,09987714 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,03354528 0,09971604 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,03354528 0,09955547 ! alditol metabolic process GO:0019400 6 6 0,000 0,03354528 0,09939541 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,03354528 0,09923587 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,03354528 0,09907684 ! maternal placenta development GO:0001893 6 6 0,000 0,03354528 0,09891832 ! regulation of embryonic development GO:0045995 6 6 0,000 0,03354528 0,0987603 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,03354528 0,09860279 ! regulation of body fluid levels GO:0050878 55 52 1,000 0,03474813 0,10197581 ! response to light stimulus GO:0009416 53 52 1,000 0,03474813 0,10181369 ! response to hypoxia GO:0001666 53 53 1,000 0,03598359 0,10526629 ! regulation of T cell activation GO:0050863 53 53 1,000 0,03598359 0,10509947 ! regulation of protein transport GO:0051223 53 53 1,000 0,03598359 0,10493317 GO:0070201|regulation of establishment of protein localization, ! response to oxygen levels GO:0070482 55 54 1,000 0,03723599 0,10841378 ! hormone metabolic process GO:0042445 55 54 1,000 0,03723599 0,10824278 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,03723599 0,10807232 ! in utero embryonic development GO:0001701 55 55 1,000 0,03850509 0,11158002 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,03850509 0,11140485 ! respiratory burst GO:0045730 7 7 0,000 0,03902851 0,11274223 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,03902851 0,1125658 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,03902851 0,11238991 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,03902851 0,11221458 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,03902851 0,11203979 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,03902851 0,11186554 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,03902851 0,11169184 ! regulation of chemokine production GO:0032642 7 7 0,000 0,03902851 0,11151867 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,03902851 0,11134604 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,03902851 0,11117395 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,03902851 0,11100238 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,03902851 0,11083135 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,03902851 0,11066084 ! gene silencing by RNA GO:0031047 7 7 0,000 0,03902851 0,11049085 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,03902851 0,11032139 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,03902851 0,11015244 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,03902851 0,10998401 ! axis specification GO:0009798 7 7 0,000 0,03902851 0,1098161 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,03902851 0,10964869 ! visual behavior GO:0007632 7 7 0,000 0,03902851 0,1094818 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,03902851 0,10931542 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,03902851 0,10914953 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,03902851 0,10898416 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,03902851 0,10881928 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,03902851 0,1086549 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,03902851 0,10849102 ! digestive system development GO:0055123 7 7 0,000 0,03902851 0,10832763 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,03902851 0,10816473 ! protein targeting to ER GO:0045047 8 7 0,000 0,03902851 0,10800232 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,03902851 0,1078404 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,03902851 0,10767896 ! endoderm development GO:0007492 7 7 0,000 0,03902851 0,107518 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,03902851 0,10735753 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,03902851 0,10719753 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,03902851 0,10703801 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,03902851 0,10687897 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,03902851 0,10672039 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,03902851 0,10656229 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,03902851 0,10640465 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,03902851 0,10624748 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,03902851 0,10609077 ! response to X-ray GO:0010165 7 7 0,000 0,03902851 0,10593453 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,03902851 0,10577874 ! UV protection GO:0009650 7 7 0,000 0,03902851 0,10562341 ! DNA integration GO:0015074 7 7 0,000 0,03902851 0,10546854 ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,03902851 0,10531412 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,03902851 0,10516015 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,03902851 0,10500663 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,03902851 0,10485356 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,03902851 0,10470094 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,03902851 0,10454876 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,03902851 0,10439702 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,03902851 0,10424572 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,03902851 0,10409485 ! axon cargo transport GO:0008088 7 7 0,000 0,03902851 0,10394443 ! eating behavior GO:0042755 7 7 0,000 0,03902851 0,10379444 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,03902851 0,10364488 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,03902851 0,10349575 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,03902851 0,10334705 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,03902851 0,10319877 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,03902851 0,10305092 ! cranial nerve development GO:0021545 7 7 0,000 0,03902851 0,1029035 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,03902851 0,10275649 ! induction of an organ GO:0001759 7 7 0,000 0,03902851 0,10260991 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,03902851 0,10246374 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,03902851 0,10231799 ! autonomic nervous system development GO:0048483 7 7 0,000 0,03902851 0,10217265 ! intracellular lipid transport GO:0032365 7 7 0,000 0,03902851 0,10202772 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,03902851 0,10188321 ! platelet activation GO:0030168 8 7 0,000 0,03902851 0,1017391 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,03902851 0,1015954 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,03902851 0,10145211 ! natural killer cell activation GO:0030101 7 7 0,000 0,03902851 0,10130922 ! response to gamma radiation GO:0010332 8 7 0,000 0,03902851 0,10116673 ! NADP metabolic process GO:0006739 7 7 0,000 0,03902851 0,10102464 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,03902851 0,10088295 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,03902851 0,10074166 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,03902851 0,10060076 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,03902851 0,10046026 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,03902851 0,10032014 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,03902851 0,10018042 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,03902851 0,10004109 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,03902851 0,09990214 ! cell-cell recognition GO:0009988 8 7 0,000 0,03902851 0,09976358 ! hormone catabolic process GO:0042447 7 7 0,000 0,03902851 0,09962541 ! dopamine metabolic process GO:0042417 7 7 0,000 0,03902851 0,09948761 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,03902851 0,0993502 ! oxygen transport GO:0015671 7 7 0,000 0,03902851 0,09921316 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,03902851 0,09907651 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,03902851 0,09894022 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,03902851 0,09880432 ! regulation of axon extension GO:0030516 7 7 0,000 0,03902851 0,09866878 ! cell killing GO:0001906 7 7 0,000 0,03902851 0,09853362 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,03902851 0,09839883 ! adult feeding behavior GO:0008343 7 7 0,000 0,03902851 0,0982644 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,03902851 0,09813035 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,03902851 0,09799665 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,03902851 0,09786332 ! response to cold GO:0009409 7 7 0,000 0,03902851 0,09773036 ! extracellular structure organization GO:0043062 56 56 1,000 0,0397907 0,09950374 ! regulation of nervous system development GO:0051960 57 56 1,000 0,0397907 0,09936891 ! regulation of protein localization GO:0032880 58 57 1,000 0,04109258 0,10248121 ! regulation of cell development GO:0060284 60 59 1,000 0,04374431 0,10894697 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,04448143 0,11063329 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,04448143 0,11048419 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,04448143 0,11033549 ! positive regulation of translation GO:0045727 8 8 0,000 0,04448143 0,11018719 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,04448143 0,11003928 ! superoxide anion generation GO:0042554 8 8 0,000 0,04448143 0,10989178 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,04448143 0,10974467 ! cGMP metabolic process GO:0046068 8 8 0,000 0,04448143 0,10959795 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,04448143 0,10945162 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,04448143 0,10930569 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,04448143 0,10916014 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,04448143 0,10901498 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,04448143 0,10887021 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,04448143 0,10872582 ! zinc ion transport GO:0006829 8 8 0,000 0,04448143 0,10858181 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,04448143 0,10843818 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,04448143 0,10829494 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,04448143 0,10815207 ! lipid localization GO:0010876 8 8 0,000 0,04448143 0,10800957 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,04448143 0,10786746 ! response to cAMP GO:0051591 8 8 0,000 0,04448143 0,10772571 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,04448143 0,10758434 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,04448143 0,10744334 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,04448143 0,10730271 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,04448143 0,10716244 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,04448143 0,10702254 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,04448143 0,10688301 ! sensory perception of taste GO:0050909 8 8 0,000 0,04448143 0,10674384 ! organelle fusion GO:0048284 8 8 0,000 0,04448143 0,10660503 ! pancreas development GO:0031016 8 8 0,000 0,04448143 0,10646658 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,04448143 0,10632849 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,04448143 0,10619076 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,04448143 0,10605339 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,04448143 0,10591637 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,04448143 0,1057797 ! sperm motility GO:0030317 8 8 0,000 0,04448143 0,10564338 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,04448143 0,10550742 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,04448143 0,10537181 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,04448143 0,10523654 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,04448143 0,10510162 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,04448143 0,10496705 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,04448143 0,10483282 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,04448143 0,10469894 ! Golgi organization GO:0007030 8 8 0,000 0,04448143 0,10456539 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,04448143 0,10443219 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,04448143 0,10429932 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,04448143 0,10416679 ! fructose metabolic process GO:0006000 8 8 0,000 0,04448143 0,1040346 ! mannose metabolic process GO:0006013 9 8 0,000 0,04448143 0,10390275 ! NAD metabolic process GO:0019674 8 8 0,000 0,04448143 0,10377122 ! sex determination GO:0007530 8 8 0,000 0,04448143 0,10364003 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,04448143 0,10350918 ! plasma membrane fusion GO:0045026 8 8 0,000 0,04448143 0,10337865 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,04448143 0,10324845 ! response to fungus GO:0009620 8 8 0,000 0,04448143 0,10311857 ! stem cell differentiation GO:0048863 8 8 0,000 0,04448143 0,10298903 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,04448143 0,10285981 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,04448143 0,10273091 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,04448143 0,10260234 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,04448143 0,10247408 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,04448143 0,10234615 ! regulation of vasodilation GO:0042312 8 8 0,000 0,04448143 0,10221854 ! vasoconstriction GO:0042310 8 8 0,000 0,04448143 0,10209124 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,04448143 0,10196426 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,04448143 0,1018376 ! sensory perception of pain GO:0019233 8 8 0,000 0,04448143 0,10171125 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,04448143 0,10158521 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,04448143 0,10145949 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,04448143 0,10133408 ! chromatin silencing GO:0006342 8 8 0,000 0,04448143 0,10120897 ! tissue regeneration GO:0042246 8 8 0,000 0,04448143 0,10108418 ! salivary gland development GO:0007431 8 8 0,000 0,04448143 0,10095969 ! T cell homeostasis GO:0043029 8 8 0,000 0,04448143 0,10083551 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,04448143 0,10071163 ! water homeostasis GO:0030104 8 8 0,000 0,04448143 0,10058806 ! cofactor transport GO:0051181 8 8 0,000 0,04448143 0,10046479 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,04448143 0,10034182 ! acid secretion GO:0046717 8 8 0,000 0,04448143 0,10021915 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,04448143 0,10009678 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,04448143 0,09997472 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,04448143 0,09985294 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,04448143 0,09973147 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,04448143 0,09961029 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,04448143 0,0994894 ! regulation of RNA stability GO:0043487 8 8 0,000 0,04448143 0,09936881 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,04448143 0,09924851 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,04448143 0,0991285 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,04448143 0,09900878 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,04448143 0,09888934 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,04448143 0,0987702 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,04448143 0,09865134 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,04448143 0,09853277 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,04448143 0,09841449 ! developmental induction GO:0031128 8 8 0,000 0,04448143 0,09829648 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,04448143 0,09817876 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,04448143 0,09806132 ! actin filament polymerization GO:0030041 9 8 0,000 0,04448143 0,09794417 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,04448143 0,09782729 ! peptide hormone processing GO:0016486 8 8 0,000 0,04448143 0,09771069 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,04448143 0,09759437 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,04448143 0,09747832 ! cellular respiration GO:0045333 62 61 1,000 0,04645859 0,10169023 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,04645859 0,1015696 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 0,04645859 0,10144926 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,04645859 0,1013292 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! morphogenesis of an epithelium GO:0002009 63 62 1,000 0,04783866 0,10421589 GO:0060429|epithelium development, ! glucose metabolic process GO:0006006 63 63 1,000 0,04923374 0,10712843 ! lactation GO:0007595 10 9 0,000 0,04990419 0,10845922 ! embryonic pattern specification GO:0009880 10 9 0,000 0,04990419 0,10833147 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,04990419 0,10820402 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,04990419 0,10807687 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,04990419 0,10795002 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,04990419 0,10782347 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,04990419 0,10769721 ! viral genome replication GO:0019079 9 9 0,000 0,04990419 0,10757125 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,04990419 0,10744558 ! copper ion transport GO:0006825 9 9 0,000 0,04990419 0,10732021 ! lipid phosphorylation GO:0046834 9 9 0,000 0,04990419 0,10719513 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,04990419 0,10707034 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,04990419 0,10694584 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,04990419 0,10682162 ! RNA polyadenylation GO:0043631 9 9 0,000 0,04990419 0,1066977 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,04990419 0,10657407 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,04990419 0,10645072 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,04990419 0,10632765 ! phospholipid efflux GO:0033700 9 9 0,000 0,04990419 0,10620487 ! response to alkaloid GO:0043279 10 9 0,000 0,04990419 0,10608237 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,04990419 0,10596016 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,04990419 0,10583823 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,04990419 0,10571657 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,04990419 0,1055952 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,04990419 0,1054741 ! response to ethanol GO:0045471 9 9 0,000 0,04990419 0,10535329 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,04990419 0,10523274 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,04990419 0,10511248 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,04990419 0,10499249 ! methionine metabolic process GO:0006555 9 9 0,000 0,04990419 0,10487277 ! glutamine metabolic process GO:0006541 9 9 0,000 0,04990419 0,10475332 ! cerebral cortex development GO:0021987 9 9 0,000 0,04990419 0,10463415 ! response to osmotic stress GO:0006970 9 9 0,000 0,04990419 0,10451525 ! pigmentation during development GO:0048066 9 9 0,000 0,04990419 0,10439662 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,04990419 0,10427825 ! central nervous system neuron development GO:0021954 10 9 0,000 0,04990419 0,10416016 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,04990419 0,10404233 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,04990419 0,10392477 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,04990419 0,10380747 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,04990419 0,10369044 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,04990419 0,10357367 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,04990419 0,10345716 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,04990419 0,10334092 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,04990419 0,10322494 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,04990419 0,10310921 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,04990419 0,10299375 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,04990419 0,10287854 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,04990419 0,1027636 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,04990419 0,1026489 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,04990419 0,10253447 ! DNA replication initiation GO:0006270 9 9 0,000 0,04990419 0,10242029 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,04990419 0,10230636 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,04990419 0,10219269 ! regulation of cellular pH GO:0030641 9 9 0,000 0,04990419 0,10207927 ! histone acetylation GO:0016573 9 9 0,000 0,04990419 0,1019661 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,04990419 0,10185318 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,04990419 0,10174051 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,04990419 0,10162809 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,04990419 0,10151591 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,04990419 0,10140399 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,04990419 0,10129231 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,04990419 0,10118088 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,04990419 0,10106969 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,04990419 0,10095875 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,04990419 0,10084805 ! collagen catabolic process GO:0030574 9 9 0,000 0,04990419 0,10073759 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,04990419 0,10062737 ! purine base metabolic process GO:0006144 9 9 0,000 0,04990419 0,1005174 ! gas transport GO:0015669 9 9 0,000 0,04990419 0,10040766 ! cholesterol efflux GO:0033344 9 9 0,000 0,04990419 0,10029817 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,04990419 0,10018891 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,04990419 0,10007989 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,04990419 0,09997111 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,04990419 0,09986256 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,04990419 0,09975425 ! defense response to virus GO:0051607 9 9 0,000 0,04990419 0,09964617 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,04990419 0,09953833 ! actin filament-based movement GO:0030048 9 9 0,000 0,04990419 0,09943072 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,04990419 0,09932335 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,05064363 0,10068631 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,05064363 0,10057781 ! regulation of hormone levels GO:0010817 66 65 1,000 0,05206812 0,10329553 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,05350702 0,10603596 ! muscle contraction GO:0006936 67 67 1,000 0,05496012 0,10879861 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,05529696 0,10934796 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,05529696 0,10923076 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,05529696 0,10911381 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,05529696 0,10899711 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,05529696 0,10888066 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,05529696 0,10876446 ! neuron maturation GO:0042551 10 10 0,000 0,05529696 0,1086485 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,05529696 0,1085328 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,05529696 0,10841734 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,05529696 0,10830212 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,05529696 0,10818715 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,05529696 0,10807243 ! hormone secretion GO:0046879 10 10 0,000 0,05529696 0,10795794 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,05529696 0,1078437 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,05529696 0,1077297 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,05529696 0,10761594 ! inositol metabolic process GO:0006020 10 10 0,000 0,05529696 0,10750242 ! cAMP metabolic process GO:0046058 10 10 0,000 0,05529696 0,10738914 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,05529696 0,1072761 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,05529696 0,1071633 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,05529696 0,10705073 ! glial cell development GO:0021782 10 10 0,000 0,05529696 0,1069384 ! phototransduction GO:0007602 11 10 0,000 0,05529696 0,10682631 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,05529696 0,10671445 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,05529696 0,10660282 ! myoblast differentiation GO:0045445 10 10 0,000 0,05529696 0,10649143 ! centrosome cycle GO:0007098 10 10 0,000 0,05529696 0,10638027 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,05529696 0,10626934 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,05529696 0,10615864 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,05529696 0,10604818 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,05529696 0,10593794 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,05529696 0,10582793 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,05529696 0,10571815 ! protein polyubiquitination GO:0000209 10 10 0,000 0,05529696 0,1056086 ! glutamate metabolic process GO:0006536 11 10 0,000 0,05529696 0,10549927 ! plasma membrane organization GO:0007009 10 10 0,000 0,05529696 0,10539017 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,05529696 0,1052813 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,05529696 0,10517265 ! lysosomal transport GO:0007041 10 10 0,000 0,05529696 0,10506422 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,05529696 0,10495602 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,05529696 0,10484804 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,05529696 0,10474028 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,05529696 0,10463275 ! exocrine system development GO:0035272 10 10 0,000 0,05529696 0,10452543 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,05529696 0,10441834 ! embryo implantation GO:0007566 11 10 0,000 0,05529696 0,10431146 ! regulation of protein binding GO:0043393 11 10 0,000 0,05529696 0,1042048 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,05529696 0,10409836 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,05529696 0,10399214 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,05529696 0,10388613 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,05529696 0,10378034 ! protein export from nucleus GO:0006611 10 10 0,000 0,05529696 0,10367477 ! negative regulation of immune response GO:0050777 10 10 0,000 0,05529696 0,10356941 ! cytolysis GO:0019835 10 10 0,000 0,05529696 0,10346426 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,05529696 0,10335933 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,05529696 0,10325461 ! histone deacetylation GO:0016575 10 10 0,000 0,05529696 0,1031501 ! mRNA splice site selection GO:0006376 11 10 0,000 0,05529696 0,1030458 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,05529696 0,10294171 ! gland morphogenesis GO:0022612 10 10 0,000 0,05529696 0,10283784 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,05529696 0,10273417 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,05529696 0,10263071 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,05529696 0,10252746 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,05529696 0,10242442 ! regulation of epidermis development GO:0045682 10 10 0,000 0,05529696 0,10232158 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,05529696 0,10221895 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,05529696 0,10211653 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,05529696 0,10201431 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,05529696 0,1019123 ! nerve development GO:0021675 10 10 0,000 0,05529696 0,10181049 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,05529696 0,10170888 ! gut development GO:0048565 10 10 0,000 0,05529696 0,10160747 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,05529696 0,10150627 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,05529696 0,10140527 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,05529696 0,10130447 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,05529696 0,10120387 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,05529696 0,10110347 ! response to radiation GO:0009314 70 68 1,000 0,05642723 0,10306777 ! protein secretion GO:0009306 11 11 0,000 0,0606599 0,11068931 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,0606599 0,11057982 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,0606599 0,11047055 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,0606599 0,1103615 ! negative regulation of defense response GO:0031348 11 11 0,000 0,0606599 0,11025266 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,0606599 0,11014404 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,0606599 0,11003563 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,0606599 0,10992743 ! signal complex assembly GO:0007172 11 11 0,000 0,0606599 0,10981945 ! microtubule-based transport GO:0010970 11 11 0,000 0,0606599 0,10971168 ! endothelial cell migration GO:0043542 11 11 0,000 0,0606599 0,10960412 ! peroxisomal transport GO:0043574 11 11 0,000 0,0606599 0,10949677 ! protein amino acid methylation GO:0006479 11 11 0,000 0,0606599 0,10938963 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,0606599 0,1092827 ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,0606599 0,10917598 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,0606599 0,10906946 ! T cell proliferation GO:0042098 11 11 0,000 0,0606599 0,10896316 ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,0606599 0,10885706 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,0606599 0,10875117 ! spinal cord development GO:0021510 11 11 0,000 0,0606599 0,10864548 ! smooth muscle contraction GO:0006939 11 11 0,000 0,0606599 0,10854 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,0606599 0,10843472 ! digestive system process GO:0022600 11 11 0,000 0,0606599 0,10832965 ! mitotic spindle organization GO:0007052 11 11 0,000 0,0606599 0,10822478 ! fucose metabolic process GO:0006004 11 11 0,000 0,0606599 0,10812012 ! membrane budding GO:0006900 11 11 0,000 0,0606599 0,10801565 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,0606599 0,10791139 ! monoamine transport GO:0015844 11 11 0,000 0,0606599 0,10780733 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,0606599 0,10770347 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,0606599 0,10759981 ! body fluid secretion GO:0007589 11 11 0,000 0,0606599 0,10749635 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,0606599 0,10739308 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,0606599 0,10729002 ! intermediate filament-based process GO:0045103 11 11 0,000 0,0606599 0,10718715 ! interaction with host GO:0051701 11 11 0,000 0,0606599 0,10708448 ! membrane depolarization GO:0051899 11 11 0,000 0,0606599 0,10698201 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,0606599 0,10687973 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,0606599 0,10677765 ! oogenesis GO:0048477 11 11 0,000 0,0606599 0,10667576 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,0606599 0,10657407 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,0606599 0,10647257 ! vitamin transport GO:0051180 11 11 0,000 0,0606599 0,10637127 ! muscle maintenance GO:0046716 12 11 0,000 0,0606599 0,10627015 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,0606599 0,10616923 ! hindbrain development GO:0030902 11 11 0,000 0,0606599 0,1060685 ! steroid catabolic process GO:0006706 11 11 0,000 0,0606599 0,10596796 ! endocrine process GO:0050886 11 11 0,000 0,0606599 0,10586761 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,0606599 0,10576746 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,0606599 0,10566749 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,0606599 0,10556771 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,0606599 0,10546811 ! regulation of cell migration GO:0030334 71 71 1,000 0,06091063 0,10580423 ! calcium ion homeostasis GO:0055074 71 71 1,000 0,06091063 0,1057046 GO:0006874|cellular calcium ion homeostasis, ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,06091063 0,10560516 ! muscle system process GO:0003012 72 72 1,000 0,06243181 0,10814082 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,06243181 0,10803928 ! electron transport chain GO:0022900 75 74 1,000 0,06551312 0,11326517 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,06599318 0,11398822 ! translational initiation GO:0006413 12 12 0,000 0,06599318 0,11388149 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,06599318 0,11377495 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,06599318 0,11366862 ! initiation of viral infection GO:0019059 12 12 0,000 0,06599318 0,11356249 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,06599318 0,11345655 ! iron ion transport GO:0006826 13 12 0,000 0,06599318 0,11335082 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,06599318 0,11324528 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,06599318 0,11313993 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,06599318 0,11303478 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,06599318 0,11292983 ! collagen metabolic process GO:0032963 12 12 0,000 0,06599318 0,11282507 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,06599318 0,11272051 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,06599318 0,11261614 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,06599318 0,11251196 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,06599318 0,11240797 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,06599318 0,11230418 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,06599318 0,11220058 GO:0042744|hydrogen peroxide catabolic process, ! microtubule organizing center organization GO:0031023 12 12 0,000 0,06599318 0,11209717 GO:0051297|centrosome organization, ! retinoid metabolic process GO:0001523 12 12 0,000 0,06599318 0,11199395 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,06599318 0,11189092 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,06599318 0,11178808 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,06599318 0,11168542 GO:0006505|GPI anchor metabolic process, ! acute-phase response GO:0006953 12 12 0,000 0,06599318 0,11158296 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,06599318 0,11148068 ! vacuolar transport GO:0007034 12 12 0,000 0,06599318 0,1113786 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,06599318 0,11127669 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,06599318 0,11117498 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,06599318 0,11107345 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,06599318 0,1109721 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,06599318 0,11087094 ! male gonad development GO:0008584 12 12 0,000 0,06599318 0,11076997 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,06599318 0,11066918 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,06599318 0,11056857 ! renal system process GO:0003014 12 12 0,000 0,06599318 0,11046814 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,06599318 0,1103679 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,06599318 0,11026784 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,06599318 0,11016796 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,06599318 0,11006826 ! pallium development GO:0021543 13 12 0,000 0,06599318 0,10996874 ! cell fate determination GO:0001709 12 12 0,000 0,06599318 0,1098694 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,06599318 0,10977024 ! somitogenesis GO:0001756 13 12 0,000 0,06599318 0,10967126 ! G1 phase GO:0051318 13 12 0,000 0,06599318 0,10957246 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,06599318 0,10947383 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,06599318 0,10937538 ! detection of light stimulus GO:0009583 13 12 0,000 0,06599318 0,10927711 ! synaptogenesis GO:0007416 12 12 0,000 0,06599318 0,10917902 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,06599318 0,1090811 ! hormone transport GO:0009914 12 12 0,000 0,06599318 0,10898336 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,06599318 0,10888579 ! heme biosynthetic process GO:0006783 12 12 0,000 0,06599318 0,1087884 ! spermatid differentiation GO:0048515 13 12 0,000 0,06599318 0,10869118 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,06599318 0,10859413 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,06599318 0,10849726 ! neural tube closure GO:0001843 13 12 0,000 0,06599318 0,10840056 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,06599318 0,10830403 ! negative regulation of translation GO:0017148 12 12 0,000 0,06599318 0,10820767 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,06599318 0,10811149 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,06599318 0,10801548 ! response to oxidative stress GO:0006979 76 75 1,000 0,06707286 0,10968526 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,06864509 0,11215683 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,07022962 0,1146441 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,07129694 0,11628342 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,07129694 0,11618061 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,07129694 0,11607797 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,07129694 0,11597552 ! phenol metabolic process GO:0018958 13 13 0,000 0,07129694 0,11587325 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,07129694 0,11577116 ! gluconeogenesis GO:0006094 13 13 0,000 0,07129694 0,11566925 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,07129694 0,11556752 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,07129694 0,11546596 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,07129694 0,11536459 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,07129694 0,11526339 ! regeneration GO:0031099 13 13 0,000 0,07129694 0,11516237 ! keratinization GO:0031424 13 13 0,000 0,07129694 0,11506153 ! post-embryonic development GO:0009791 14 13 0,000 0,07129694 0,11496086 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,07129694 0,11486037 ! patterning of blood vessels GO:0001569 13 13 0,000 0,07129694 0,11476006 ! vasculogenesis GO:0001570 13 13 0,000 0,07129694 0,11465992 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,07129694 0,11455995 ! regulation of innate immune response GO:0045088 13 13 0,000 0,07129694 0,11446016 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,07129694 0,11436055 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,07129694 0,1142611 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,07129694 0,11416183 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,07129694 0,11406273 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,07129694 0,11396381 ! autophagy GO:0006914 13 13 0,000 0,07129694 0,11386505 ! receptor metabolic process GO:0043112 14 13 0,000 0,07129694 0,11376647 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,07129694 0,11366805 ! ureteric bud development GO:0001657 13 13 0,000 0,07129694 0,11356981 ! cell aging GO:0007569 13 13 0,000 0,07129694 0,11347173 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,07129694 0,11337383 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,07129694 0,11327609 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,07129694 0,11317852 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,07129694 0,11308113 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,07129694 0,11298389 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,07129694 0,11288683 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,07129694 0,11278993 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,07129694 0,1126932 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,07129694 0,11259663 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,07129694 0,11250023 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,07129694 0,11240399 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,07129694 0,11230792 ! vasodilation GO:0042311 14 13 0,000 0,07129694 0,11221201 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,07129694 0,11211627 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,07129694 0,11202069 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,07129694 0,11192527 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,07129694 0,11183001 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,07129694 0,11173492 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,07129694 0,11163999 ! immunoglobulin production GO:0002377 13 13 0,000 0,07129694 0,11154522 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,07129694 0,11145061 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,07129694 0,11135616 ! cell-cell junction organization GO:0045216 13 13 0,000 0,07129694 0,11126187 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,07129694 0,11116774 GO:0001952|regulation of cell-matrix adhesion, ! response to cytokine stimulus GO:0034097 13 13 0,000 0,07129694 0,11107377 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,07129694 0,11097996 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,07129694 0,1108863 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,07129694 0,11079281 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,07129694 0,11069947 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,07129694 0,11060629 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,07129694 0,11051326 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,07129694 0,11042039 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,07129694 0,11032768 ! telomere organization GO:0032200 13 13 0,000 0,07129694 0,11023512 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,07129694 0,11014272 ! regulation of amine transport GO:0051952 13 13 0,000 0,07129694 0,11005048 ! tissue homeostasis GO:0001894 13 13 0,000 0,07129694 0,10995838 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,07129694 0,10986644 ! protein tetramerization GO:0051262 13 13 0,000 0,07129694 0,10977466 ! metal ion homeostasis GO:0055065 78 78 1,000 0,07182627 0,11049733 ! regulation of locomotion GO:0040012 79 79 1,000 0,07343485 0,11287775 ! neuron fate commitment GO:0048663 14 14 0,000 0,07657136 0,11760085 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,07657136 0,11750293 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,07657136 0,11740517 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,07657136 0,11730758 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,07657136 0,11721015 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,07657136 0,11711288 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,07657136 0,11701577 ! protein amino acid acylation GO:0043543 14 14 0,000 0,07657136 0,11691882 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,07657136 0,11682203 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,07657136 0,11672541 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,07657136 0,11662894 ! vesicle docking GO:0048278 14 14 0,000 0,07657136 0,11653263 ! superoxide metabolic process GO:0006801 15 14 0,000 0,07657136 0,11643648 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,07657136 0,11634049 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,07657136 0,11624466 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,07657136 0,11614899 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,07657136 0,11605347 ! hair cycle GO:0042633 14 14 0,000 0,07657136 0,11595811 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,07657136 0,1158629 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,07657136 0,11576786 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,07657136 0,11567296 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,07657136 0,11557823 ! lysosome organization GO:0007040 14 14 0,000 0,07657136 0,11548365 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,07657136 0,11538922 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,07657136 0,11529495 ! peptide transport GO:0015833 14 14 0,000 0,07657136 0,11520083 ! primary neural tube formation GO:0014020 15 14 0,000 0,07657136 0,11510687 ! peptide cross-linking GO:0018149 14 14 0,000 0,07657136 0,11501305 ! regulation of behavior GO:0050795 14 14 0,000 0,07657136 0,1149194 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,07657136 0,11482589 ! base-excision repair GO:0006284 14 14 0,000 0,07657136 0,11473253 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,07657136 0,11463933 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,07657136 0,11454628 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,07657136 0,11445338 ! formation of primary germ layer GO:0001704 14 14 0,000 0,07657136 0,11436063 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,07657136 0,11426803 ! collagen fibril organization GO:0030199 14 14 0,000 0,07657136 0,11417558 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,07657136 0,11408328 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,07657136 0,11399113 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,07657136 0,11389913 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,07657136 0,11380727 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,07657136 0,11371557 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,07657136 0,11362401 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,07657136 0,1135326 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,07657136 0,11344133 ! tube development GO:0035295 83 81 1,000 0,07668712 0,11352157 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,08181659 0,12101763 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,08181659 0,12092058 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,08181659 0,12082369 ! positive regulation of ossification GO:0045778 15 15 0,000 0,08181659 0,12072696 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,08181659 0,12063037 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,08181659 0,12053395 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,08181659 0,12043767 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,08181659 0,12034155 ! response to vitamin GO:0033273 15 15 0,000 0,08181659 0,12024559 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,08181659 0,12014977 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,08181659 0,12005411 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,08181659 0,11995861 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,08181659 0,11986325 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,08181659 0,11976804 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,08181659 0,11967299 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,08181659 0,11957809 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,08181659 0,11948333 ! heme metabolic process GO:0042168 15 15 0,000 0,08181659 0,11938873 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,08181659 0,11929428 ! chromosome condensation GO:0030261 15 15 0,000 0,08181659 0,11919997 ! response to ionizing radiation GO:0010212 16 15 0,000 0,08181659 0,11910582 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,08181659 0,11901181 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,08181659 0,11891796 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,08181659 0,11882425 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,08181659 0,11873068 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,08181659 0,11863727 ! phospholipid transport GO:0015914 15 15 0,000 0,08181659 0,118544 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,08181659 0,11845088 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,08181659 0,1183579 ! glutathione metabolic process GO:0006749 16 15 0,000 0,08181659 0,11826507 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,08181659 0,11817239 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,08181659 0,11807985 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,08181659 0,11798745 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,08181659 0,11789521 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,08181659 0,1178031 ! protein homooligomerization GO:0051260 15 15 0,000 0,08181659 0,11771114 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,08181659 0,11761932 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 0,08332716 0,11969755 ! hexose metabolic process GO:0019318 87 86 1,000 0,0850144 0,12202612 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,08703278 0,124826 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,08703278 0,12472893 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,08703278 0,12463202 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,08703278 0,12453525 ! learning GO:0007612 16 16 0,000 0,08703278 0,12443864 ! circadian rhythm GO:0007623 16 16 0,000 0,08703278 0,12434218 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,08703278 0,12424586 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,08703278 0,1241497 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,08703278 0,12405368 ! vacuole organization GO:0007033 16 16 0,000 0,08703278 0,12395781 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,08703278 0,12386209 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,08703278 0,12376652 ! vesicle targeting GO:0006903 17 16 0,000 0,08703278 0,12367109 ! segmentation GO:0035282 17 16 0,000 0,08703278 0,12357582 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,08703278 0,12348068 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,08703278 0,1233857 ! iron ion homeostasis GO:0055072 16 16 0,000 0,08703278 0,12329086 ! positive regulation of cell development GO:0010720 16 16 0,000 0,08703278 0,12319617 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,08703278 0,12310162 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,08703278 0,12300721 ! cell fate specification GO:0001708 16 16 0,000 0,08703278 0,12291296 ! pentose metabolic process GO:0019321 16 16 0,000 0,08703278 0,12281884 ! fatty acid transport GO:0015908 16 16 0,000 0,08703278 0,12272487 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,08703278 0,12263105 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,08703278 0,12253736 ! cofactor catabolic process GO:0051187 16 16 0,000 0,08703278 0,12244382 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,08703278 0,12235043 ! polyol metabolic process GO:0019751 16 16 0,000 0,08703278 0,12225717 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,08703278 0,12216406 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,08703278 0,12207109 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,08703278 0,12197826 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,08703278 0,12188557 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,08703278 0,12179302 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,08703278 0,12170061 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,08703278 0,12160835 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,08703278 0,12151622 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,09013876 0,12575756 ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 0,09186722 0,12807208 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,09222009 0,12846684 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,09222009 0,12836981 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,09222009 0,12827293 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,09222009 0,12817619 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,09222009 0,1280796 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,09222009 0,12798315 ! leukocyte adhesion GO:0007159 17 17 0,000 0,09222009 0,12788685 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,09222009 0,1277907 ! sensory perception of smell GO:0007608 17 17 0,000 0,09222009 0,12769469 ! glucose transport GO:0015758 17 17 0,000 0,09222009 0,12759882 ! cell junction assembly GO:0034329 18 17 0,000 0,09222009 0,1275031 ! tissue remodeling GO:0048771 17 17 0,000 0,09222009 0,12740752 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,09222009 0,12731208 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,09222009 0,12721679 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,09222009 0,12712164 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,09222009 0,12702663 ! neural crest cell development GO:0014032 19 17 0,000 0,09222009 0,12693176 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,09222009 0,12683704 ! negative regulation of cell development GO:0010721 18 17 0,000 0,09222009 0,12674245 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,09222009 0,12664801 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,09222009 0,12655371 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,09222009 0,12645954 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,09222009 0,12636552 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,09222009 0,12627164 ! pigmentation GO:0043473 17 17 0,000 0,09222009 0,1261779 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,09222009 0,12608429 ! adult locomotory behavior GO:0008344 17 17 0,000 0,09222009 0,12599083 ! embryonic organ development GO:0048568 17 17 0,000 0,09222009 0,1258975 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,09222009 0,12580431 ! liver development GO:0001889 17 17 0,000 0,09222009 0,12571126 ! gene silencing GO:0016458 17 17 0,000 0,09222009 0,12561835 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,09360558 0,12741143 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,09737868 0,13244938 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,09737868 0,13235171 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,09737868 0,13225417 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,09737868 0,13215678 ! meiosis I GO:0007127 18 18 0,000 0,09737868 0,13205954 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,09737868 0,13196244 ! membrane docking GO:0022406 18 18 0,000 0,09737868 0,13186548 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,09737868 0,13176866 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,09737868 0,13167198 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,09737868 0,13157545 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,09737868 0,13147906 ! hexose transport GO:0008645 18 18 0,000 0,09737868 0,13138281 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,09737868 0,1312867 GO:0055092|sterol homeostasis, ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,09737868 0,13119073 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,09737868 0,1310949 ! ceramide metabolic process GO:0006672 18 18 0,000 0,09737868 0,13099921 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,09737868 0,13090366 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,09737868 0,13080825 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,09737868 0,13071297 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,09737868 0,13061784 ! B cell differentiation GO:0030183 18 18 0,000 0,09737868 0,13052285 ! BMP signaling pathway GO:0030509 18 18 0,000 0,09737868 0,13042799 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,09737868 0,13033327 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,09737868 0,13023869 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,09737868 0,13014424 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,09737868 0,13004994 ! regulation of response to stress GO:0080134 97 94 1,000 0,09887842 0,13195722 ! epidermis development GO:0008544 94 94 1,000 0,09887842 0,13186174 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,10250871 0,13660416 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,10250871 0,13650545 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,10250871 0,13640689 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,10250871 0,13630848 ! glial cell differentiation GO:0010001 19 19 0,000 0,10250871 0,1362102 ! regulation of pH GO:0006885 19 19 0,000 0,10250871 0,13611207 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,10250871 0,13601407 ! feeding behavior GO:0007631 19 19 0,000 0,10250871 0,13591622 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,10250871 0,13581851 ! peroxisome organization GO:0007031 19 19 0,000 0,10250871 0,13572094 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,10250871 0,13562351 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,10250871 0,13552622 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,10250871 0,13542907 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,10250871 0,13533205 ! metanephros development GO:0001656 19 19 0,000 0,10250871 0,13523518 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,10250871 0,13513845 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,10250871 0,13504185 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,10250871 0,13494539 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,10250871 0,13484907 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,10250871 0,13475289 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,10250871 0,13465684 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,10250871 0,13456093 ! eye morphogenesis GO:0048592 19 19 0,000 0,10250871 0,13446516 ! regulation of cell shape GO:0008360 21 19 0,000 0,10250871 0,13436952 ! placenta development GO:0001890 19 19 0,000 0,10250871 0,13427402 ! response to heat GO:0009408 19 19 0,000 0,10250871 0,13417866 ! vesicle localization GO:0051648 20 19 0,000 0,10250871 0,13408343 ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 0,10603784 0,13860124 ! glycoprotein metabolic process GO:0009100 99 98 1,000 0,10603784 0,13850301 ! blood circulation GO:0008015 99 98 1,000 0,10603784 0,13840492 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 1,000 0,10603784 0,13830697 ! regulation of muscle development GO:0048634 21 20 0,000 0,10761032 0,14025871 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,10761032 0,14015959 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,10761032 0,14006061 ! negative regulation of binding GO:0051100 21 20 0,000 0,10761032 0,13996176 ! organic ether metabolic process GO:0018904 20 20 0,000 0,10761032 0,13986306 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,10761032 0,1397645 ! neural tube development GO:0021915 21 20 0,000 0,10761032 0,13966607 ! nucleus organization GO:0006997 20 20 0,000 0,10761032 0,13956778 ! phagocytosis GO:0006909 21 20 0,000 0,10761032 0,13946963 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,10761032 0,13937162 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,10761032 0,13927375 ! protein targeting to membrane GO:0006612 22 20 0,000 0,10761032 0,13917601 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,10761032 0,13907841 ! chromatin remodeling GO:0006338 20 20 0,000 0,10761032 0,13898095 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,10761032 0,13888363 ! lipid oxidation GO:0034440 20 20 0,000 0,10761032 0,13878644 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,10761032 0,13868938 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,10761032 0,13859247 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,10761032 0,13849568 ! RNA modification GO:0009451 20 20 0,000 0,10761032 0,13839904 ! single fertilization GO:0007338 21 20 0,000 0,10761032 0,13830252 ! anti-apoptosis GO:0006916 100 99 1,000 0,1078497 0,13851359 ! ectoderm development GO:0007398 99 99 1,000 0,1078497 0,13841713 ! hemopoiesis GO:0030097 104 100 1,000 0,10967007 0,14065548 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,11268367 0,14442003 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,11268367 0,14431967 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,11268367 0,14421945 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,11268367 0,14411937 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,11268367 0,14401942 ! ear morphogenesis GO:0042471 21 21 0,000 0,11268367 0,14391962 ! organic anion transport GO:0015711 21 21 0,000 0,11268367 0,14381995 ! cholesterol transport GO:0030301 21 21 0,000 0,11268367 0,14372042 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,11268367 0,14362103 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,11268367 0,14352177 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,11268367 0,14342266 ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,11268367 0,14332368 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,11268367 0,14322483 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,11268367 0,14312613 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,11268367 0,14302755 ! regulation of proteolysis GO:0030162 21 21 0,000 0,11268367 0,14292912 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,11268367 0,14283082 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,11268367 0,14273265 ! negative regulation of protein transport GO:0051224 21 21 0,000 0,11268367 0,14263462 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,11772892 0,1489186 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,11772892 0,14881646 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,11772892 0,14871446 ! sister chromatid segregation GO:0000819 22 22 0,000 0,11772892 0,1486126 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,11772892 0,14851088 ! regulation of ion transport GO:0043269 22 22 0,000 0,11772892 0,1484093 ! odontogenesis GO:0042476 22 22 0,000 0,11772892 0,14830786 ! cell junction organization GO:0034330 23 22 0,000 0,11772892 0,14820655 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,11772892 0,14810539 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,11772892 0,14800436 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,11772892 0,14790347 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,11772892 0,14780272 ! spindle organization GO:0007051 22 22 0,000 0,11772892 0,14770211 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,11772892 0,14760163 ! cell chemotaxis GO:0060326 23 22 0,000 0,11772892 0,14750129 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,11772892 0,14740108 ! male sex differentiation GO:0046661 22 22 0,000 0,11772892 0,14730101 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,11772892 0,14720108 ! biopolymer methylation GO:0043414 22 22 0,000 0,11772892 0,14710128 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,11772892 0,14700162 ! neuron migration GO:0001764 22 22 0,000 0,11772892 0,1469021 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,11772892 0,1468027 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,11772892 0,14670344 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,11772892 0,14660432 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,11772892 0,14650533 ! aerobic respiration GO:0009060 22 22 0,000 0,11772892 0,14640647 ! cytokine production GO:0001816 22 22 0,000 0,11772892 0,14630775 ! cytokinesis GO:0000910 23 22 0,000 0,11772892 0,14620916 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,11772892 0,1461107 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,12274621 0,15223503 ! viral infectious cycle GO:0019058 23 23 0,000 0,12274621 0,15213266 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,12274621 0,15203042 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,12274621 0,15192831 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,12274621 0,15182635 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,12274621 0,15172452 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,12274621 0,15162283 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,12274621 0,15152127 ! endocrine system development GO:0035270 23 23 0,000 0,12274621 0,15141985 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,12274621 0,15131857 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,12274621 0,15121742 ! lipid homeostasis GO:0055088 23 23 0,000 0,12274621 0,15111641 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,12274621 0,15101553 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,12274621 0,15091478 ! cell projection assembly GO:0030031 25 23 0,000 0,12274621 0,15081417 ! mitochondrial transport GO:0006839 24 24 0,000 0,12773569 0,15684003 ! gliogenesis GO:0042063 24 24 0,000 0,12773569 0,15673561 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,12773569 0,15663132 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,12773569 0,15652718 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,12773569 0,15642318 ! T cell differentiation GO:0030217 24 24 0,000 0,12773569 0,15631931 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,12773569 0,15621558 ! fertilization GO:0009566 25 24 0,000 0,12773569 0,15611199 ! maintenance of protein location GO:0045185 25 24 0,000 0,12773569 0,15600854 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,12773569 0,15590522 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,12773569 0,15580204 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,13269752 0,16174705 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,13269752 0,16164014 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,13269752 0,16153338 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,13269752 0,16142675 ! cellular component disassembly GO:0022411 26 25 0,000 0,13269752 0,16132027 ! endosome transport GO:0016197 25 25 0,000 0,13269752 0,16121393 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,13269752 0,16110773 ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,13269752 0,16100167 ! excretion GO:0007588 25 25 0,000 0,13269752 0,16089575 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,13269752 0,16078996 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,13269752 0,16068432 ! gastrulation GO:0007369 25 25 0,000 0,13269752 0,16057881 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,13269752 0,16047345 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,13269752 0,16036822 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,13269752 0,16026313 ! positive regulation of binding GO:0051099 27 26 0,000 0,13763185 0,16611362 ! positive regulation of defense response GO:0031349 26 26 0,000 0,13763185 0,1660049 ! glycolysis GO:0006096 26 26 0,000 0,13763185 0,16589633 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,13763185 0,1657879 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,13763185 0,16567962 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,13763185 0,16557147 ! cellular defense response GO:0006968 26 26 0,000 0,13763185 0,16546347 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,13763185 0,1653556 ! double-strand break repair GO:0006302 27 26 0,000 0,13763185 0,16524788 ! regulation of protein secretion GO:0050708 26 26 0,000 0,13763185 0,1651403 ! germ cell development GO:0007281 27 26 0,000 0,13763185 0,16503285 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,13763185 0,16492555 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,13763185 0,16481838 ! response to insulin stimulus GO:0032868 28 26 0,000 0,13763185 0,16471136 ! maintenance of location in cell GO:0051651 27 26 0,000 0,13763185 0,16460447 ! chloride transport GO:0006821 27 27 0,000 0,14253881 0,17036254 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,14253881 0,17025213 ! learning or memory GO:0007611 28 27 0,000 0,14253881 0,17014186 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,14253881 0,17003174 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,14253881 0,16992176 ! peptide metabolic process GO:0006518 29 27 0,000 0,14253881 0,16981192 ! activation of caspase activity GO:0006919 27 27 0,000 0,14253881 0,16970222 ! mesenchymal cell development GO:0014031 29 27 0,000 0,14253881 0,16959266 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,14253881 0,16948325 ! defense response to bacterium GO:0042742 27 27 0,000 0,14253881 0,16937398 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,14253881 0,16926484 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,14253881 0,16915585 ! cell growth GO:0016049 27 27 0,000 0,14253881 0,169047 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,14741857 0,17472182 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! neuromuscular process GO:0050905 28 28 0,000 0,14741857 0,17460953 ! carbohydrate transport GO:0008643 28 28 0,000 0,14741857 0,17449739 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,14741857 0,17438539 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,14741857 0,17427353 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,14741857 0,17416181 ! histone modification GO:0016570 28 28 0,000 0,14741857 0,17405024 ! developmental growth GO:0048589 28 28 0,000 0,14741857 0,17393882 ! cartilage development GO:0051216 29 28 0,000 0,14741857 0,17382753 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,15227127 0,17943475 ! viral reproductive process GO:0022415 29 29 0,000 0,15227127 0,1793201 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,15227127 0,17920559 ! leukocyte migration GO:0050900 30 29 0,000 0,15227127 0,17909123 ! antigen processing and presentation GO:0019882 29 29 0,000 0,15227127 0,17897701 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,15227127 0,17886294 ! tRNA processing GO:0008033 29 29 0,000 0,15227127 0,17874901 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,15227127 0,17863523 ! covalent chromatin modification GO:0016569 29 29 0,000 0,15227127 0,1785216 ! adult behavior GO:0030534 30 29 0,000 0,15227127 0,17840811 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,15227127 0,17829476 ! transition metal ion transport GO:0000041 31 30 0,000 0,15709705 0,18382848 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,15709705 0,18371184 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,15709705 0,18359535 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,15709705 0,183479 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,15709705 0,1833628 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,15709705 0,18324675 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,15709705 0,18313084 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,15709705 0,18301508 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,15709705 0,18289947 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,15709705 0,182784 ! response to temperature stimulus GO:0009266 30 30 0,000 0,15709705 0,18266868 ! regulation of ossification GO:0030278 30 30 0,000 0,15709705 0,18255351 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,15709705 0,18243848 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,15709705 0,18232359 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,15709705 0,18220885 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,15709705 0,18209425 ! vesicle organization GO:0016050 30 30 0,000 0,15709705 0,1819798 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,15709705 0,18186549 ! establishment of organelle localization GO:0051656 31 30 0,000 0,15709705 0,18175133 ! regulation of translational initiation GO:0006446 31 31 0,000 0,16189606 0,18718597 ! membrane fusion GO:0006944 31 31 0,000 0,16189606 0,18706861 ! B cell activation GO:0042113 31 31 0,000 0,16189606 0,1869514 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,16189606 0,18683434 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,16189606 0,18671742 ! ion transmembrane transport GO:0034220 31 31 0,000 0,16189606 0,18660065 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,16189606 0,18648402 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,16189606 0,18636754 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,16189606 0,18625121 ! regulation of DNA replication GO:0006275 32 31 0,000 0,16189606 0,18613502 ! regulation of heart contraction GO:0008016 31 31 0,000 0,16189606 0,18601898 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,16189606 0,18590308 ! camera-type eye development GO:0043010 31 31 0,000 0,16189606 0,18578732 ! extracellular matrix organization GO:0030198 31 31 0,000 0,16189606 0,18567171 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,16189606 0,18555624 ! cell redox homeostasis GO:0045454 32 32 0,000 0,16666844 0,19090736 ! glucose catabolic process GO:0006007 32 32 0,000 0,16666844 0,19078878 ! lipid modification GO:0030258 32 32 0,000 0,16666844 0,19067035 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,16666844 0,19055207 ! nuclear export GO:0051168 32 32 0,000 0,16666844 0,19043394 ! kidney development GO:0001822 32 32 0,000 0,16666844 0,19031595 ! maintenance of location GO:0051235 33 32 0,000 0,16666844 0,19019811 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,17141434 0,19549297 ! amino acid transport GO:0006865 33 33 0,000 0,17141434 0,19537207 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,17141434 0,19525132 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,17141434 0,19513072 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,17141434 0,19501027 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,17141434 0,19488997 ! regulation of actin filament length GO:0030832 34 34 0,000 0,17613391 0,20013242 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,17613391 0,20000911 ! response to metal ion GO:0010038 34 34 0,000 0,17613391 0,19988595 ! ear development GO:0043583 34 34 0,000 0,17613391 0,19976295 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,17613391 0,19964009 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,17613391 0,19951739 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,17613391 0,19939483 ! secondary metabolic process GO:0019748 34 34 0,000 0,17613391 0,19927243 ! response to peptide hormone stimulus GO:0043434 36 34 0,000 0,17613391 0,19915018 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,17613391 0,19902807 ! viral reproduction GO:0016032 34 34 0,000 0,17613391 0,19890612 ! acute inflammatory response GO:0002526 35 35 0,000 0,18082727 0,20408124 ! regulation of cellular component size GO:0032535 35 35 0,000 0,18082727 0,20395634 ! mesoderm development GO:0007498 35 35 0,000 0,18082727 0,2038316 ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,18082727 0,20370701 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,18082727 0,20358257 ! inorganic anion transport GO:0015698 35 35 0,000 0,18082727 0,20345828 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,18082727 0,20333414 ! regulation of immune effector process GO:0002697 35 35 0,000 0,18082727 0,20321016 ! hydrogen transport GO:0006818 36 36 0,000 0,18549458 0,20832816 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,18549458 0,20820129 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,18549458 0,20807457 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,18549458 0,207948 ! regulation of mitosis GO:0007088 37 36 0,000 0,18549458 0,20782159 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,18549458 0,20769533 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,18549458 0,20756922 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,18549458 0,20744327 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,18549458 0,20731747 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,18549458 0,20719183 ! activation of immune response GO:0002253 36 36 0,000 0,18549458 0,20706633 ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,19013598 0,21211901 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,19013598 0,21199069 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 0,000 0,19013598 0,21186252 GO:0051327|M phase of meiotic cell cycle, ! response to drug GO:0042493 37 37 0,000 0,19013598 0,2117345 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,19013598 0,21160665 ! eye development GO:0001654 37 37 0,000 0,19013598 0,21147894 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,19013598 0,21135139 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,19013598 0,21122399 ! adaptive immune response GO:0002250 37 37 0,000 0,19013598 0,21109675 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! neurotransmitter transport GO:0006836 40 38 0,000 0,1947516 0,21609103 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,1947516 0,21596101 ! exocytosis GO:0006887 40 38 0,000 0,1947516 0,21583115 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,1947516 0,21570144 ! hexose catabolic process GO:0019320 38 38 0,000 0,1947516 0,21557189 ! RNA elongation GO:0006354 38 38 0,000 0,1947516 0,21544249 ! meiotic cell cycle GO:0051321 38 38 0,000 0,1947516 0,21531325 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,19934158 0,22025572 ! activation of MAPK activity GO:0000187 39 39 0,000 0,19934158 0,22012375 ! response to unfolded protein GO:0006986 39 39 0,000 0,19934158 0,21999194 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,19934158 0,21986029 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,19934158 0,21972879 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,19934158 0,21959745 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,19934158 0,21946627 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,19934158 0,21933525 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,19934158 0,21920438 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,19934158 0,21907367 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,19934158 0,21894311 ! limb development GO:0060173 39 39 0,000 0,19934158 0,21881271 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 0,000 0,19934158 0,21868246 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,20390607 0,22355675 ! DNA catabolic process GO:0006308 41 40 0,000 0,20390607 0,22342384 ! organelle localization GO:0051640 41 40 0,000 0,20390607 0,22329108 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,20844521 0,2281262 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,20844521 0,22799081 ! amine catabolic process GO:0009310 42 41 0,000 0,20844521 0,22785558 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,20844521 0,22772052 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,20844521 0,22758561 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,20844521 0,22745087 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,20844521 0,22731628 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,20844521 0,22718185 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,21295912 0,23196433 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,21295912 0,23182732 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,21295912 0,23169047 ! protein ubiquitination GO:0016567 43 42 0,000 0,21295912 0,23155378 ! response to protein stimulus GO:0051789 42 42 0,000 0,21295912 0,23141725 ! forebrain development GO:0030900 43 42 0,000 0,21295912 0,23128088 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,21295912 0,23114467 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,21744794 0,23587791 ! alcohol catabolic process GO:0046164 43 43 0,000 0,21744794 0,23573915 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,21744794 0,23560056 ! humoral immune response GO:0006959 44 44 0,000 0,22191182 0,24029582 ! mRNA transport GO:0051028 44 44 0,000 0,22191182 0,24015472 ! protein import into nucleus GO:0006606 44 44 0,000 0,22191182 0,24001378 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,22191182 0,23987301 ! vitamin metabolic process GO:0006766 44 44 0,000 0,22191182 0,23973241 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,22191182 0,23959197 ! amine biosynthetic process GO:0009309 46 45 0,000 0,22635089 0,24424162 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,22635089 0,2440987 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,22635089 0,24395595 ! regulation of DNA binding GO:0051101 47 45 0,000 0,22635089 0,24381337 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,22635089 0,24367096 ! nuclear import GO:0051170 45 45 0,000 0,22635089 0,24352871 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,23076527 0,24813325 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,23076527 0,24798857 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,23076527 0,24784405 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,23515511 0,25241169 ! regulation of blood pressure GO:0008217 48 47 0,000 0,23515511 0,25226476 ! amine transport GO:0015837 47 47 0,000 0,23515511 0,25211801 ! regulation of catabolic process GO:0009894 48 47 0,000 0,23515511 0,25197143 ! calcium ion transport GO:0006816 48 48 0,000 0,23952053 0,25649991 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,23952053 0,25635095 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,23952053 0,25620217 ! protein localization in nucleus GO:0034504 48 48 0,000 0,23952053 0,25605356 ! DNA recombination GO:0006310 48 48 0,000 0,23952053 0,25590513 ! leukocyte differentiation GO:0002521 50 49 0,000 0,24386168 0,26039228 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,24386168 0,2602415 ! divalent metal ion transport GO:0070838 49 49 0,000 0,24386168 0,2600909 ! response to nutrient GO:0007584 49 49 0,000 0,24386168 0,25994047 ! response to bacterium GO:0009617 50 49 0,000 0,24386168 0,25979021 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,24386168 0,25964013 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,24386168 0,25949023 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,24817867 0,2639315 ! regulation of DNA metabolic process GO:0051052 51 50 0,000 0,24817867 0,26377929 ! chromatin assembly GO:0031497 50 50 0,000 0,24817867 0,26362726 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,24817867 0,2634754 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,24817867 0,26332372 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,24817867 0,26317221 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,24817867 0,26302087 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,24817867 0,26286971 ! anterior/posterior pattern formation GO:0009952 51 50 0,000 0,24817867 0,26271872 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,25247165 0,26710979 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,25247165 0,26695654 ! positive regulation of immune response GO:0050778 51 51 0,000 0,25247165 0,26680347 ! rRNA metabolic process GO:0016072 51 51 0,000 0,25247165 0,26665057 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,25247165 0,26649785 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,25247165 0,26634531 ! RNA localization GO:0006403 52 52 0,000 0,25674074 0,27069404 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,25674074 0,27053927 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,25674074 0,27038467 ! cell fate commitment GO:0045165 52 52 0,000 0,25674074 0,27023026 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,25674074 0,27007602 ! sodium ion transport GO:0006814 53 53 0,000 0,26098607 0,27438524 ! tRNA metabolic process GO:0006399 53 53 0,000 0,26098607 0,2742288 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,26098607 0,27407255 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,26098607 0,27391647 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,26098607 0,27376057 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,26520777 0,27803067 ! response to virus GO:0009615 54 54 0,000 0,26520777 0,27787261 ! sulfur metabolic process GO:0006790 55 54 0,000 0,26520777 0,27771472 ! nucleosome organization GO:0034728 55 55 0,000 0,26940596 0,28195071 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,26940596 0,28179069 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,26940596 0,28163085 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,26940596 0,2814712 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,27358079 0,28567104 ! regulation of binding GO:0051098 60 57 0,000 0,27773236 0,28984187 ! ATP metabolic process GO:0046034 57 57 0,000 0,27773236 0,28967784 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,27773236 0,289514 ! innate immune response GO:0045087 58 58 0,000 0,28186082 0,29365149 ! dephosphorylation GO:0016311 60 59 0,000 0,28596627 0,29776036 ! carboxylic acid transport GO:0046942 59 59 0,000 0,28596627 0,29759223 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,28596627 0,29742429 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,28596627 0,29725654 ! protein localization in organelle GO:0033365 59 59 0,000 0,28596627 0,29708898 ! immune effector process GO:0002252 59 59 0,000 0,28596627 0,2969216 ! potassium ion transport GO:0006813 60 60 0,000 0,29004886 0,30099102 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,29004886 0,30082164 ! protein polymerization GO:0051258 65 60 0,000 0,29004886 0,30065245 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,2941087 0,30468934 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,29814591 0,30869827 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,29814591 0,30852494 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,29814591 0,3083518 ! protein import GO:0017038 62 62 0,000 0,29814591 0,30817886 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,29814591 0,30800612 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,30216062 0,31197873 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,30216062 0,31180405 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,30216062 0,31162956 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,30615296 0,31557041 ! angiogenesis GO:0001525 65 64 0,000 0,30615296 0,31539402 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,30615296 0,31521782 ! anion transport GO:0006820 65 65 0,000 0,31012303 0,31912716 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,31407097 0,32300937 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,31407097 0,32282922 ! DNA packaging GO:0006323 66 66 0,000 0,31407097 0,32264927 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,31407097 0,32246953 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,31799689 0,32631864 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,31799689 0,32613705 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,32190092 0,32995739 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,32190092 0,32977398 ! regulation of translation GO:0006417 69 69 0,000 0,32578316 0,33356576 ! sensory perception of sound GO:0007605 71 69 0,000 0,32578316 0,33338055 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 0,000 0,32578316 0,33319554 ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,32578316 0,33301074 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,32964375 0,3367702 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,3334828 0,34050349 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,3334828 0,34031495 ! ribosome biogenesis GO:0042254 71 71 0,000 0,3334828 0,34012661 ! secretion by cell GO:0032940 75 72 0,000 0,33730041 0,34383001 ! sensory organ development GO:0007423 72 72 0,000 0,33730041 0,34363995 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,34487184 0,35115956 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,34862588 0,35478603 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,34862588 0,35459023 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,35235896 0,3581895 ! microtubule-based movement GO:0007018 82 78 0,000 0,35976268 0,36551412 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,35976268 0,36531274 ! regulation of immune response GO:0050776 78 78 0,000 0,35976268 0,36511158 ! nuclear transport GO:0051169 79 79 0,000 0,36343355 0,36863403 GO:0006913|nucleocytoplasmic transport, ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,36708391 0,37213182 ! lymphocyte activation GO:0046649 82 81 0,000 0,37071387 0,37560509 ! lipid catabolic process GO:0016042 82 81 0,000 0,37071387 0,37539872 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,37791304 0,38247871 ! ncRNA processing GO:0034470 83 83 0,000 0,37791304 0,38226879 ! blood vessel morphogenesis GO:0048514 84 83 0,000 0,37791304 0,38205909 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,38148246 0,38545624 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,38503193 0,38882951 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,38503193 0,38861657 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,38856155 0,39196439 GO:0006644|phospholipid metabolic process, ! male gamete generation GO:0048232 90 88 0,000 0,39556167 0,39880752 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,39556167 0,39858948 ! chemotaxis GO:0006935 90 89 0,000 0,39903238 0,40186704 GO:0042330|taxis, ! brain development GO:0007420 91 90 0,000 0,40248368 0,40512147 ! DNA replication GO:0006260 91 91 0,000 0,40591565 0,40835292 ! visual perception GO:0007601 93 92 0,000 0,40932842 0,41156153 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,40932842 0,41133712 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,40932842 0,41111296 ! blood vessel development GO:0001568 95 94 0,000 0,41609675 0,41768318 ! pattern specification process GO:0007389 96 94 0,000 0,41609675 0,4174558 ! cofactor metabolic process GO:0051186 95 94 0,000 0,41609675 0,41722868 ! vasculature development GO:0001944 97 96 0,000 0,42278949 0,4237091 ! endocytosis GO:0006897 99 98 0,000 0,42940746 0,43010758 GO:0010324|membrane invagination, ! response to hormone stimulus GO:0009725 102 100 0,000 0,43595147 0,43642508 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 0,000 0,43595147 0,43618815 ! response to other organism GO:0051707 101 100 0,000 0,43595147 0,43595147