pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6536-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! G1/S transition of mitotic cell cycle GO:0000082 115 46 5,000 4,268E-08 1,027E-04 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 3,000 4,097E-07 4,929E-04 ! negative regulation of protein kinase activity GO:0006469 130 67 5,000 4,227E-07 3,39E-04 ! negative regulation of kinase activity GO:0033673 131 68 5,000 4,62E-07 2,779E-04 ! negative regulation of transferase activity GO:0051348 140 72 5,000 6,504E-07 3,13E-04 ! negative regulation of hormone secretion GO:0046888 25 17 3,000 7,097E-07 2,846E-04 ! hemoglobin biosynthetic process GO:0042541 7 5 2,000 7,452E-07 2,561E-04 ! cellular glucose homeostasis GO:0001678 5 5 2,000 7,452E-07 2,241E-04 ! negative regulation of macrophage differentiation GO:0045650 6 5 2,000 7,452E-07 1,992E-04 ! positive regulation of hormone secretion GO:0046887 32 19 3,000 1,148E-06 2,763E-04 ! activation of MAPKKK activity GO:0000185 12 6 2,000 1,486E-06 3,25E-04 ! negative regulation of B cell activation GO:0050869 13 6 2,000 1,486E-06 2,979E-04 ! ovarian follicle development GO:0001541 35 21 3,000 1,761E-06 3,26E-04 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 3,097E-06 5,322E-04 ! interphase of mitotic cell cycle GO:0051329 209 95 5,000 3,341E-06 5,359E-04 ! interphase GO:0051325 213 98 5,000 4,004E-06 6,021E-04 ! hemoglobin metabolic process GO:0020027 13 8 2,000 4,134E-06 5,851E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 4,134E-06 5,526E-04 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 4,328E-06 5,481E-04 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of lymphocyte activation GO:0051250 53 27 3,000 5,064E-06 6,092E-04 ! motor axon guidance GO:0008045 16 9 2,000 6,182E-06 7,083E-04 ! regulation of macrophage differentiation GO:0045649 15 9 2,000 6,182E-06 6,761E-04 ! negative regulation of lymphocyte differentiation GO:0045620 19 9 2,000 6,182E-06 6,467E-04 ! negative regulation of leukocyte activation GO:0002695 56 30 3,000 7,83E-06 7,849E-04 ! regulation of B cell activation GO:0050864 50 30 3,000 7,83E-06 7,536E-04 ! regulation of B cell differentiation GO:0045577 19 10 2,000 8,804E-06 8,147E-04 ! ovulation cycle process GO:0022602 49 31 3,000 8,96E-06 7,985E-04 ! ovulation cycle GO:0042698 51 32 3,000 1,021E-05 8,771E-04 ! reproductive structure development GO:0048608 113 71 4,000 1,333E-05 1,106E-03 ! negative regulation of secretion GO:0051048 63 35 3,000 1,472E-05 1,18E-03 ! female gonad development GO:0008585 58 35 3,000 1,472E-05 1,142E-03 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 2,000 1,604E-05 1,206E-03 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 2,000 1,604E-05 1,17E-03 ! negative regulation of cell activation GO:0050866 65 36 3,000 1,65E-05 1,168E-03 ! carbohydrate homeostasis GO:0033500 53 38 3,000 2,054E-05 1,412E-03 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 3,000 2,054E-05 1,373E-03 GO:0046660|female sex differentiation, ! regulation of hormone secretion GO:0046883 62 40 3,000 2,527E-05 1,643E-03 ! activation of MAPKK activity GO:0000186 35 16 2,000 4,033E-05 2,553E-03 ! regulation of lymphocyte differentiation GO:0045619 81 48 3,000 5,24E-05 3,233E-03 ! negative regulation of immune system process GO:0002683 95 50 3,000 6,161E-05 3,706E-03 ! actin filament bundle formation GO:0051017 42 19 2,000 6,913E-05 4,057E-03 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 2,000 8,108E-05 4,645E-03 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 2,000 9,43E-05 5,276E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 1,033E-04 5,647E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 1,088E-04 5,82E-03 ! positive regulation of secretion GO:0051047 95 59 3,000 1,182E-04 6,183E-03 ! gonad development GO:0008406 98 62 3,000 1,435E-04 7,345E-03 ! response to starvation GO:0042594 42 25 2,000 1,611E-04 8,073E-03 ! multicellular organism reproduction GO:0032504 111 64 3,000 1,624E-04 7,972E-03 GO:0048609|reproductive process in a multicellular organism, ! regulation of cytokine biosynthetic process GO:0042035 95 65 3,000 1,724E-04 8,298E-03 ! positive regulation of histone modification GO:0031058 5 5 1,000 1,777E-04 8,385E-03 ! Notch receptor processing GO:0007220 8 5 1,000 1,777E-04 8,224E-03 ! regulation of activin receptor signaling pathway GO:0032925 14 5 1,000 1,777E-04 8,068E-03 ! skeletal myofibril assembly GO:0014866 10 5 1,000 1,777E-04 7,919E-03 ! cardiac muscle fiber development GO:0048739 10 5 1,000 1,777E-04 7,775E-03 ! positive regulation of transporter activity GO:0032411 8 5 1,000 1,777E-04 7,636E-03 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 1,777E-04 7,502E-03 ! peptidyl-histidine phosphorylation GO:0018106 9 5 1,000 1,777E-04 7,373E-03 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 1,000 1,777E-04 7,248E-03 ! phospholipid scrambling GO:0017121 8 5 1,000 1,777E-04 7,127E-03 ! regulation of interferon-gamma production GO:0032649 39 26 2,000 1,815E-04 7,159E-03 ! actin filament organization GO:0007015 148 66 3,000 1,83E-04 7,1E-03 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 2,000 2,273E-04 8,68E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 2,527E-04 9,501E-03 ! negative regulation of gliogenesis GO:0014014 18 6 1,000 2,659E-04 9,841E-03 GO:0045686|negative regulation of glial cell differentiation, ! skeletal muscle contraction GO:0003009 6 6 1,000 2,659E-04 9,692E-03 ! rhythmic process GO:0048511 128 75 3,000 2,996E-04 0,01075841 ! development of primary sexual characteristics GO:0045137 124 76 3,000 3,152E-04 0,01115254 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 2,000 3,399E-04 0,0118509 ! prostate gland development GO:0030850 13 7 1,000 3,712E-04 0,01275734 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 3,712E-04 0,01257766 ! regulation of gluconeogenesis GO:0006111 7 7 1,000 3,712E-04 0,01240297 ! amyloid precursor protein catabolic process GO:0042987 11 7 1,000 3,712E-04 0,01223307 ! peptidyl-histidine modification GO:0018202 16 7 1,000 3,712E-04 0,01206775 ! negative regulation of transport GO:0051051 153 84 3,000 4,618E-04 0,01481437 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 4,832E-04 0,01529739 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 4,935E-04 0,01542038 ! ER overload response GO:0006983 12 8 1,000 4,935E-04 0,01522268 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 4,935E-04 0,01502999 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 4,935E-04 0,01484212 ! sex differentiation GO:0007548 145 90 3,000 5,997E-04 0,01781234 ! mRNA catabolic process GO:0006402 71 39 2,000 6,128E-04 0,01797962 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 6,327E-04 0,01834178 ! regulation of histone modification GO:0031056 12 9 1,000 6,327E-04 0,01812343 ! keratinocyte proliferation GO:0043616 14 9 1,000 6,327E-04 0,01791021 ! microtubule bundle formation GO:0001578 21 9 1,000 6,327E-04 0,01770195 ! amyloid precursor protein metabolic process GO:0042982 14 9 1,000 6,327E-04 0,01749848 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 1,000 6,327E-04 0,01729963 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 6,327E-04 0,01710526 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 6,327E-04 0,0169152 ! musculoskeletal movement GO:0050881 14 9 1,000 6,327E-04 0,01672932 GO:0050879|multicellular organismal movement, ! regulation of Rho protein signal transduction GO:0035023 213 95 3,000 7,35E-04 0,01922266 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 7,626E-04 0,01972968 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 7,887E-04 0,02018791 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 7,887E-04 0,01997541 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 7,887E-04 0,01976733 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 7,887E-04 0,01956355 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 1,000 7,887E-04 0,01936392 ! epithelial cell development GO:0002064 20 10 1,000 7,887E-04 0,01916832 ! regulation of gliogenesis GO:0014013 23 10 1,000 7,887E-04 0,01897664 GO:0045685|regulation of glial cell differentiation, ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 7,887E-04 0,01878875 ! blastocyst formation GO:0001825 17 10 1,000 7,887E-04 0,01860455 ! localization within membrane GO:0051668 20 10 1,000 7,887E-04 0,01842392 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 8,173E-04 0,01890749 ! cell cycle arrest GO:0007050 213 100 3,000 8,907E-04 0,02040961 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 9,339E-04 0,02119851 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 9,613E-04 0,02161602 ! detection of mechanical stimulus GO:0050982 22 11 1,000 9,613E-04 0,02141587 ! adult heart development GO:0007512 14 11 1,000 9,613E-04 0,0212194 ! temperature homeostasis GO:0001659 17 11 1,000 9,613E-04 0,0210265 ! neuroblast proliferation GO:0007405 24 11 1,000 9,613E-04 0,02083707 ! Notch signaling pathway GO:0007219 96 48 2,000 1,128E-03 0,0242285 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 1,128E-03 0,02401409 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,15E-03 0,02427876 ! hippocampus development GO:0021766 26 12 1,000 1,15E-03 0,02406764 ! positive regulation of cell growth GO:0030307 22 12 1,000 1,15E-03 0,02386016 ! focal adhesion formation GO:0048041 35 12 1,000 1,15E-03 0,02365623 ! membrane protein proteolysis GO:0033619 25 12 1,000 1,15E-03 0,02345575 GO:0006509|membrane protein ectodomain proteolysis, ! histone methylation GO:0016571 26 12 1,000 1,15E-03 0,02325864 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 1,15E-03 0,02306482 GO:0042130|negative regulation of T cell proliferation, ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 1,345E-03 0,02675289 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of lipid metabolic process GO:0045834 25 13 1,000 1,356E-03 0,02673702 ! plasma membrane organization GO:0007009 24 13 1,000 1,356E-03 0,02651965 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 1,356E-03 0,02630578 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,356E-03 0,02609533 ! regulation of fatty acid oxidation GO:0046320 27 13 1,000 1,356E-03 0,02588823 ! RNA catabolic process GO:0006401 93 53 2,000 1,504E-03 0,02849585 ! response to UV GO:0009411 104 53 2,000 1,504E-03 0,02827323 ! regulation of mRNA processing GO:0050684 24 14 1,000 1,577E-03 0,02941855 ! negative regulation of caspase activity GO:0043154 22 14 1,000 1,577E-03 0,02919225 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 1,577E-03 0,02896941 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 1,577E-03 0,02874994 ! negative regulation of cell motion GO:0051271 134 55 2,000 1,674E-03 0,03028544 ! positive regulation of cell size GO:0045793 27 15 1,000 1,815E-03 0,0325871 ! cardiac muscle contraction GO:0060048 26 15 1,000 1,815E-03 0,03234571 ! regulation of transmembrane transporter activity GO:0022898 27 15 1,000 1,815E-03 0,03210788 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! glycoprotein catabolic process GO:0006516 26 15 1,000 1,815E-03 0,03187351 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 2,068E-03 0,03606247 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 2,068E-03 0,03580303 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 2,068E-03 0,03554729 GO:0031114|regulation of microtubule depolymerization, ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 2,068E-03 0,03529518 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 2,15E-03 0,03643289 ! limbic system development GO:0021761 36 17 1,000 2,338E-03 0,03933224 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 2,338E-03 0,0390591 ! cardiac muscle tissue development GO:0048738 31 17 1,000 2,338E-03 0,03878972 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 2,338E-03 0,03852404 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 2,338E-03 0,03826197 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 2,472E-03 0,04019135 ! cell redox homeostasis GO:0045454 102 64 2,000 2,586E-03 0,04175604 ! positive regulation of cell motion GO:0051272 146 64 2,000 2,586E-03 0,04147766 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 2,623E-03 0,04178815 ! protein amino acid ADP-ribosylation GO:0006471 33 18 1,000 2,623E-03 0,04151323 ! cell-substrate junction assembly GO:0007044 54 18 1,000 2,623E-03 0,0412419 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 2,623E-03 0,04097409 ! regulation of BMP signaling pathway GO:0030510 32 18 1,000 2,623E-03 0,04070974 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 1,000 2,623E-03 0,04044878 ! skin development GO:0043588 36 19 1,000 2,923E-03 0,04479488 ! lipid phosphorylation GO:0046834 35 19 1,000 2,923E-03 0,04451137 ! neuromuscular junction development GO:0007528 34 19 1,000 2,923E-03 0,04423142 ! heart process GO:0003015 30 19 1,000 2,923E-03 0,04395498 GO:0060047|heart contraction, ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 2,923E-03 0,04368196 ! negative regulation of cell growth GO:0030308 132 67 2,000 2,946E-03 0,04375172 ! chromosome segregation GO:0007059 113 67 2,000 2,946E-03 0,0434833 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 3,072E-03 0,04507377 ! negative regulation of cell size GO:0045792 134 69 2,000 3,202E-03 0,04669295 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 2,000 3,202E-03 0,04641167 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 3,239E-03 0,04666193 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 3,239E-03 0,04638418 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 3,239E-03 0,04610972 ! cellular response to starvation GO:0009267 33 20 1,000 3,239E-03 0,04583849 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 3,239E-03 0,04557042 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 3,239E-03 0,04530548 ! peptidyl-serine modification GO:0018209 43 20 1,000 3,239E-03 0,0450436 ! negative regulation of T cell activation GO:0050868 40 20 1,000 3,239E-03 0,04478473 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 2,000 3,611E-03 0,0496526 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 2,000 3,611E-03 0,04937048 ! axon guidance GO:0007411 139 73 2,000 3,755E-03 0,05103815 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 1,000 3,916E-03 0,05293051 GO:0060415|muscle tissue morphogenesis, ! positive regulation of intracellular transport GO:0032388 37 22 1,000 3,916E-03 0,05263481 ! sarcomere organization GO:0045214 30 22 1,000 3,916E-03 0,0523424 ! positive regulation of B cell activation GO:0050871 38 22 1,000 3,916E-03 0,05205321 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 3,916E-03 0,05176721 ! protein stabilization GO:0050821 39 22 1,000 3,916E-03 0,05148432 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 4,277E-03 0,05592573 ! platelet activation GO:0030168 37 23 1,000 4,277E-03 0,05562343 ! positive regulation of ligase activity GO:0051351 124 77 2,000 4,362E-03 0,05642394 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 4,653E-03 0,05986483 ! regulation of transmembrane transport GO:0034762 38 24 1,000 4,653E-03 0,0595464 ! pallium development GO:0021543 49 24 1,000 4,653E-03 0,05923134 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 4,653E-03 0,05891959 ! activation of protein kinase activity GO:0032147 147 79 2,000 4,687E-03 0,05903635 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 4,687E-03 0,05872887 ! regulation of neuron differentiation GO:0045664 167 81 2,000 5,025E-03 0,06264927 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 5,043E-03 0,06254887 ! myelination GO:0042552 45 25 1,000 5,043E-03 0,06222811 ! protein amino acid alkylation GO:0008213 53 25 1,000 5,043E-03 0,06191062 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 5,043E-03 0,06159635 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 5,043E-03 0,06128526 ! negative regulation of cell development GO:0010721 73 25 1,000 5,043E-03 0,06097729 GO:0050768|negative regulation of neurogenesis, ! cellular response to nutrient levels GO:0031669 41 25 1,000 5,043E-03 0,0606724 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 5,449E-03 0,06522038 ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 5,449E-03 0,06489751 ! blastocyst development GO:0001824 49 26 1,000 5,449E-03 0,06457781 ! negative regulation of growth GO:0045926 155 84 2,000 5,561E-03 0,06558589 ! regulation of ligase activity GO:0051340 142 84 2,000 5,561E-03 0,06526595 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 5,868E-03 0,06853815 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 5,868E-03 0,06820705 ! fat cell differentiation GO:0045444 50 27 1,000 5,868E-03 0,06787913 ! regulation of chromosome organization GO:0033044 42 27 1,000 5,868E-03 0,06755435 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 5,868E-03 0,06723266 ! mitochondrion organization GO:0007005 148 86 2,000 5,936E-03 0,06768882 ! dendrite development GO:0016358 59 28 1,000 6,302E-03 0,07152293 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 6,302E-03 0,07118714 ! gland development GO:0048732 206 88 2,000 6,326E-03 0,07112525 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 6,75E-03 0,07553952 ! cell junction assembly GO:0034329 78 30 1,000 7,212E-03 0,08033778 ! myofibril assembly GO:0030239 47 30 1,000 7,212E-03 0,07996756 GO:0055002|striated muscle cell development, ! ensheathment of neurons GO:0007272 57 30 1,000 7,212E-03 0,07960074 GO:0008366|axon ensheathment, ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 7,367E-03 0,0809368 ! erythrocyte differentiation GO:0030218 55 31 1,000 7,688E-03 0,08408387 ! detection of stimulus GO:0051606 151 96 2,000 8,037E-03 0,08750162 ! spliceosome assembly GO:0000245 67 32 1,000 8,178E-03 0,08863588 ! response to mechanical stimulus GO:0009612 57 32 1,000 8,178E-03 0,08823841 ! muscle cell development GO:0055001 49 32 1,000 8,178E-03 0,08784449 ! peripheral nervous system development GO:0007422 64 32 1,000 8,178E-03 0,08745407 ! positive regulation of endocytosis GO:0045807 50 34 1,000 9,199E-03 0,097934 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 9,73E-03 0,1031264 ! telencephalon development GO:0021537 68 35 1,000 9,73E-03 0,10267409 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 9,73E-03 0,10222573 ! calcium-mediated signaling GO:0019722 62 35 1,000 9,73E-03 0,10178127 ! regulation of microtubule-based process GO:0032886 78 35 1,000 9,73E-03 0,10134066 ! cell junction organization GO:0034330 86 36 1,000 0,01027363 0,10654459 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 1,000 0,01083074 0,11184013 ! actomyosin structure organization GO:0031032 62 37 1,000 0,01083074 0,11136218 ! regulation of protein stability GO:0031647 73 37 1,000 0,01083074 0,1108883 ! glycogen metabolic process GO:0005977 61 37 1,000 0,01083074 0,11041843 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 0,01083074 0,10995253 ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,01140092 0,11525469 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,01140092 0,11477245 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 1,000 0,01140092 0,11429424 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 0,01198406 0,11964174 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,01198406 0,11914735 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,01318875 0,1305849 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,01318875 0,13004972 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,01318875 0,1295189 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,01381006 0,13506908 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,01381006 0,13452224 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,01444385 0,14012864 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 0,01444385 0,13956587 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,01444385 0,13900761 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,01444385 0,13845379 ! striated muscle contraction GO:0006941 77 43 1,000 0,01444385 0,13790437 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,01509002 0,14350425 ! biopolymer methylation GO:0043414 84 44 1,000 0,01509002 0,14293928 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,01574844 0,14859114 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,01574844 0,14801071 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,016419 0,15371253 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,016419 0,15311675 ! response to insulin stimulus GO:0032868 95 46 1,000 0,016419 0,15252556 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,016419 0,15193893 ! JNK cascade GO:0007254 91 47 1,000 0,0171016 0,15764921 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,0171016 0,15704749 ! methylation GO:0032259 90 47 1,000 0,0171016 0,15645035 ! positive regulation of cell cycle GO:0045787 89 48 1,000 0,01779611 0,16218726 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,01779611 0,16157523 ! regulation of action potential GO:0001508 95 49 1,000 0,01850242 0,16735651 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,01850242 0,16672971 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,01850242 0,16610758 ! ribonucleoprotein complex assembly GO:0022618 95 49 1,000 0,01850242 0,16549008 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,01850242 0,16487715 ! histone modification GO:0016570 91 50 1,000 0,01922043 0,1706434 ! chromatin remodeling GO:0006338 109 51 1,000 0,01995003 0,17646971 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,02069109 0,18235444 ! positive regulation of growth GO:0045927 90 52 1,000 0,02069109 0,18168892 ! covalent chromatin modification GO:0016569 101 52 1,000 0,02069109 0,18102823 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,02069109 0,18037233 ! synapse organization GO:0050808 85 52 1,000 0,02069109 0,17972117 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02107198 0,18237114 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02107198 0,18171748 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02107198 0,18106849 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02107198 0,18042412 ! neuron fate determination GO:0048664 7 5 0,000 0,02107198 0,17978432 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02107198 0,17914904 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02107198 0,17851823 ! polyol transport GO:0015791 12 5 0,000 0,02107198 0,17789185 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02107198 0,17726985 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02107198 0,17665219 ! response to superoxide GO:0000303 10 5 0,000 0,02107198 0,17603881 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02107198 0,17542968 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02107198 0,17482475 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02107198 0,17422398 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02107198 0,17362732 ! female meiosis GO:0007143 7 5 0,000 0,02107198 0,17303474 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02107198 0,17244618 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02107198 0,17186162 ! cobalt ion transport GO:0006824 11 5 0,000 0,02107198 0,17128101 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02107198 0,1707043 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02107198 0,17013147 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02107198 0,16956247 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02107198 0,16899726 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02107198 0,16843581 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02107198 0,16787807 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02107198 0,16732402 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02107198 0,16677361 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02107198 0,16622681 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02107198 0,16568359 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02107198 0,1651439 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02107198 0,16460772 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02107198 0,16407501 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02107198 0,16354573 ! negative chemotaxis GO:0050919 14 5 0,000 0,02107198 0,16301986 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02107198 0,16249736 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02107198 0,1619782 ! behavioral response to pain GO:0048266 9 5 0,000 0,02107198 0,16146235 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02107198 0,16094977 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02107198 0,16044044 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02107198 0,15993431 ! micturition GO:0060073 9 5 0,000 0,02107198 0,15943138 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02107198 0,15893159 ! copulation GO:0007620 9 5 0,000 0,02107198 0,15843493 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02107198 0,15794136 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02107198 0,15745086 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02107198 0,1569634 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02107198 0,15647894 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02107198 0,15599747 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02107198 0,15551895 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02107198 0,15504336 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02107198 0,15457066 ! grooming behavior GO:0007625 6 5 0,000 0,02107198 0,15410084 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02107198 0,15363387 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02107198 0,15316972 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02107198 0,15270837 ! response to protozoan GO:0001562 10 5 0,000 0,02107198 0,15224978 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02107198 0,15179394 ! lymph vessel development GO:0001945 10 5 0,000 0,02107198 0,15134083 ! endochondral ossification GO:0001958 16 5 0,000 0,02107198 0,15089041 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02107198 0,15044266 ! parathyroid gland development GO:0060017 13 5 0,000 0,02107198 0,14999757 ! anagen GO:0042640 6 5 0,000 0,02107198 0,1495551 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02107198 0,14911523 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02107198 0,14867794 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02107198 0,14824321 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02107198 0,14781101 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02107198 0,14738133 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02107198 0,14695414 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02107198 0,14652941 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02107198 0,14610714 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02107198 0,14568729 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02107198 0,14526985 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02107198 0,14485479 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02107198 0,1444421 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02107198 0,14403175 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02107198 0,14362373 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02107198 0,14321802 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02107198 0,14281458 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02107198 0,14241342 ! histidine catabolic process GO:0006548 6 5 0,000 0,02107198 0,1420145 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02107198 0,14161781 ! microvillus organization GO:0032528 7 5 0,000 0,02107198 0,14122334 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,02107198 0,14083105 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02107198 0,14044093 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02107198 0,14005298 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02107198 0,13966716 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02107198 0,13928345 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02107198 0,13890186 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02107198 0,13852234 ! polyol catabolic process GO:0046174 7 5 0,000 0,02107198 0,1381449 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02107198 0,1377695 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02107198 0,13739615 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02107198 0,1370248 ! muscle cell migration GO:0014812 8 5 0,000 0,02107198 0,13665547 ! mitochondrial fission GO:0000266 8 5 0,000 0,02107198 0,13628811 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02107198 0,13592273 ! mRNA transcription GO:0009299 9 5 0,000 0,02107198 0,1355593 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02107198 0,13519781 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02107198 0,13483824 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02107198 0,13448058 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02107198 0,13412481 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02107198 0,13377092 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02107198 0,13341889 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02107198 0,13306871 ! response to food GO:0032094 6 5 0,000 0,02107198 0,13272036 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02107198 0,13237383 ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02107198 0,13202911 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02107198 0,13168618 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02107198 0,13134502 ! forebrain neuron development GO:0021884 13 5 0,000 0,02107198 0,13100563 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02107198 0,13066798 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02107198 0,13033208 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02107198 0,12999789 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02107198 0,12966542 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02107198 0,12933464 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02107198 0,12900554 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02107198 0,12867812 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02107198 0,12835235 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02107198 0,12802823 ! basic amino acid transport GO:0015802 11 5 0,000 0,02107198 0,12770574 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02107198 0,12738487 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02107198 0,12706561 ! depyrimidination GO:0045008 10 5 0,000 0,02107198 0,12674794 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02107198 0,12643186 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02107198 0,12611736 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02107198 0,12580441 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02107198 0,12549301 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02107198 0,12518315 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02107198 0,12487482 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02107198 0,124568 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02107198 0,12426269 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02107198 0,12395887 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02107198 0,12365653 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02107198 0,12335566 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02107198 0,12305626 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02107198 0,1227583 ! response to arsenic GO:0046685 10 5 0,000 0,02107198 0,12246178 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02107198 0,12216669 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02107198 0,12187302 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02107198 0,12158076 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02107198 0,1212899 ! response to cadmium ion GO:0046686 7 5 0,000 0,02107198 0,12100042 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02107198 0,12071233 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02107198 0,1204256 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02107198 0,12014023 ! decidualization GO:0046697 11 5 0,000 0,02107198 0,11985621 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02107198 0,11957353 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02107198 0,11929218 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02107198 0,11901215 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02107198 0,11873344 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02107198 0,11845602 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02107198 0,1181799 ! neural tube patterning GO:0021532 7 5 0,000 0,02107198 0,11790506 ! embryonic cleavage GO:0040016 6 5 0,000 0,02107198 0,1176315 ! peroxisome fission GO:0016559 5 5 0,000 0,02107198 0,11735921 ! histone demethylation GO:0016577 10 5 0,000 0,02107198 0,11708817 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02107198 0,11681838 ! mitotic recombination GO:0006312 9 5 0,000 0,02107198 0,11654983 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02107198 0,11628252 ! metaphase plate congression GO:0051310 7 5 0,000 0,02107198 0,11601642 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02107198 0,11575155 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02107198 0,11548788 ! enteric nervous system development GO:0048484 8 5 0,000 0,02107198 0,1152254 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02107198 0,11496412 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02107198 0,11470402 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02107198 0,1144451 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02107198 0,11418734 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02107198 0,11393074 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02107198 0,11367529 ! plasminogen activation GO:0031639 5 5 0,000 0,02107198 0,11342098 ! B cell homeostasis GO:0001782 13 5 0,000 0,02107198 0,11316781 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02107198 0,11291576 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02107198 0,11266484 ! metaphase GO:0051323 8 5 0,000 0,02107198 0,11241503 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02107198 0,11216632 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02107198 0,11191871 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02107198 0,1116722 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02107198 0,11142676 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02107198 0,11118241 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02107198 0,11093912 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02107198 0,11069689 ! response to redox state GO:0051775 5 5 0,000 0,02107198 0,11045572 GO:0006980|redox signal response, ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02107198 0,1102156 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02107198 0,10997652 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02107198 0,10973848 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02107198 0,10950146 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02107198 0,10926547 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02107198 0,10903049 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02107198 0,10879652 ! striatum development GO:0021756 9 5 0,000 0,02107198 0,10856355 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02107198 0,10833158 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02107198 0,10810059 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02107198 0,10787059 ! glial cell migration GO:0008347 11 5 0,000 0,02107198 0,10764157 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02107198 0,10741351 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02107198 0,10718642 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02107198 0,10696029 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02107198 0,10673511 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02107198 0,10651088 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02107198 0,10628758 ! neuroprotection GO:0043526 6 5 0,000 0,02107198 0,10606522 ! neural plate development GO:0001840 8 5 0,000 0,02107198 0,10584379 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02107198 0,10562329 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02107198 0,1054037 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02107198 0,10518502 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02107198 0,10496724 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02107198 0,10475037 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02107198 0,10453439 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02107198 0,1043193 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02107198 0,10410509 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02107198 0,10389176 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02107198 0,1036793 ! spindle assembly GO:0051225 6 5 0,000 0,02107198 0,10346771 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02107198 0,10325698 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02107198 0,10304711 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02107198 0,10283809 ! drug metabolic process GO:0017144 6 5 0,000 0,02107198 0,10262991 ! stem cell division GO:0017145 11 5 0,000 0,02107198 0,10242258 GO:0048103|somatic stem cell division, ! organ regeneration GO:0031100 7 5 0,000 0,02107198 0,10221608 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02107198 0,10201042 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02107198 0,10180558 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02107198 0,10160156 ! respiratory electron transport chain GO:0022904 76 53 1,000 0,02144352 0,10318622 ! cell maturation GO:0048469 100 53 1,000 0,02144352 0,10298025 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,0222072 0,10643533 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,0222072 0,10622372 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,02298204 0,10971187 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,02298204 0,10949462 ! heart morphogenesis GO:0003007 97 55 1,000 0,02298204 0,10927822 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,02376791 0,1127921 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,02376791 0,11257007 ! muscle fiber development GO:0048747 112 57 1,000 0,02456472 0,11611536 ! positive regulation of cell migration GO:0030335 126 57 1,000 0,02456472 0,11588768 ! lipid modification GO:0030258 97 57 1,000 0,02456472 0,11566089 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,02456472 0,11543499 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,02456472 0,11520997 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,0252332 0,11811495 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,0252332 0,1178856 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,0252332 0,11765714 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,0252332 0,11742956 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,0252332 0,11720286 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,0252332 0,11697704 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,0252332 0,11675208 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,0252332 0,11652799 ! sleep GO:0030431 13 6 0,000 0,0252332 0,11630476 ! response to oxygen radical GO:0000305 11 6 0,000 0,0252332 0,11608238 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,0252332 0,11586085 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,0252332 0,11564016 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,0252332 0,11542031 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,0252332 0,1152013 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,0252332 0,11498311 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,0252332 0,11476575 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,0252332 0,11454921 ! forebrain regionalization GO:0021871 8 6 0,000 0,0252332 0,11433349 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,0252332 0,11411858 ! male meiosis GO:0007140 7 6 0,000 0,0252332 0,11390447 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,0252332 0,11369117 ! response to zinc ion GO:0010043 9 6 0,000 0,0252332 0,11347866 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,0252332 0,11326695 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,0252332 0,11305602 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,0252332 0,11284588 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,0252332 0,11263652 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,0252332 0,11242793 ! malate metabolic process GO:0006108 11 6 0,000 0,0252332 0,11222012 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,0252332 0,11201307 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,0252332 0,11180678 ! protein refolding GO:0042026 15 6 0,000 0,0252332 0,11160126 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,0252332 0,11139648 ! opsonization GO:0008228 8 6 0,000 0,0252332 0,11119246 ! mating behavior GO:0007617 7 6 0,000 0,0252332 0,11098918 ! neuron remodeling GO:0016322 15 6 0,000 0,0252332 0,11078665 ! erythrocyte maturation GO:0043249 7 6 0,000 0,0252332 0,11058485 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,0252332 0,11038379 ! equilibrioception GO:0050957 14 6 0,000 0,0252332 0,11018345 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,0252332 0,10998385 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,0252332 0,10978496 ! photoreceptor cell development GO:0042461 10 6 0,000 0,0252332 0,10958679 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,0252332 0,10938934 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,0252332 0,1091926 ! response to interferon-gamma GO:0034341 15 6 0,000 0,0252332 0,10899656 ! toxin metabolic process GO:0009404 11 6 0,000 0,0252332 0,10880122 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,0252332 0,10860659 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,0252332 0,10841265 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,0252332 0,1082194 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,0252332 0,10802684 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,0252332 0,10783496 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,0252332 0,10764376 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,0252332 0,10745324 ! thymic T cell selection GO:0045061 12 6 0,000 0,0252332 0,1072634 ! protein lipoylation GO:0009249 10 6 0,000 0,0252332 0,10707422 ! cysteine metabolic process GO:0006534 10 6 0,000 0,0252332 0,10688571 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,0252332 0,10669786 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,0252332 0,10651067 ! glutamate catabolic process GO:0006538 10 6 0,000 0,0252332 0,10632414 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,0252332 0,10613826 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,0252332 0,10595302 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,0252332 0,10576844 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,0252332 0,10558449 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,0252332 0,10540119 ! hyperosmotic response GO:0006972 9 6 0,000 0,0252332 0,10521852 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,0252332 0,10503648 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,0252332 0,10485507 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,0252332 0,10467428 ! urea metabolic process GO:0019627 7 6 0,000 0,0252332 0,10449412 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,0252332 0,10431458 ! neutrophil activation GO:0042119 8 6 0,000 0,0252332 0,10413565 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,0252332 0,10395733 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,0252332 0,10377963 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,0252332 0,10360253 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,0252332 0,10342604 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,0252332 0,10325014 ! neuron apoptosis GO:0051402 9 6 0,000 0,0252332 0,10307484 ! nucleoside salvage GO:0043174 9 6 0,000 0,0252332 0,10290014 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,0252332 0,10272603 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,0252332 0,10255251 ! T cell mediated immunity GO:0002456 16 6 0,000 0,0252332 0,10237957 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,0252332 0,10220721 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,0252332 0,10203543 ! carnitine transport GO:0015879 10 6 0,000 0,0252332 0,10186423 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,0252332 0,10169361 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0252332 0,10152355 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,0252332 0,10135406 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,0252332 0,10118514 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,0252332 0,10101678 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,0252332 0,10084898 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,0252332 0,10068173 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,0252332 0,10051504 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,0252332 0,1003489 ! establishment of spindle localization GO:0051293 12 6 0,000 0,0252332 0,10018331 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,0252332 0,10001826 ! monocyte differentiation GO:0030224 12 6 0,000 0,0252332 0,09985376 ! neural nucleus development GO:0048857 14 6 0,000 0,0252332 0,09968979 ! response to UV-C GO:0010225 11 6 0,000 0,0252332 0,09952637 ! astrocyte development GO:0014002 15 6 0,000 0,0252332 0,09936348 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,0252332 0,09920112 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,0252332 0,09903929 ! interaction with symbiont GO:0051702 13 6 0,000 0,0252332 0,09887799 ! regulation of dendrite development GO:0050773 16 6 0,000 0,0252332 0,09871721 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,0252332 0,09855695 ! response to copper ion GO:0046688 10 6 0,000 0,0252332 0,09839722 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,0252332 0,098238 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,0252332 0,09807929 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0252332 0,0979211 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,0252332 0,09776342 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,0252332 0,09760624 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,0252332 0,09744957 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0252332 0,0972934 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,0252332 0,09713773 ! hair follicle maturation GO:0048820 7 6 0,000 0,0252332 0,09698256 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,0252332 0,09682788 ! Schwann cell development GO:0014044 15 6 0,000 0,0252332 0,0966737 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,0252332 0,09652001 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,0252332 0,0963668 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,0252332 0,09621408 ! subpallium development GO:0021544 10 6 0,000 0,0252332 0,09606184 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,0252332 0,09591008 ! histone ubiquitination GO:0016574 8 6 0,000 0,0252332 0,09575881 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,0252332 0,09560801 ! maintenance of organ identity GO:0048496 9 6 0,000 0,0252332 0,09545768 ! G2 phase GO:0051319 16 6 0,000 0,0252332 0,09530782 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,0252332 0,09515844 ! establishment of planar polarity GO:0001736 7 6 0,000 0,0252332 0,09500952 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,0252332 0,09486107 ! membrane to membrane docking GO:0022614 14 6 0,000 0,0252332 0,09471308 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,0252332 0,09456555 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,0252332 0,09441848 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,0252332 0,09427187 ! receptor internalization GO:0031623 10 6 0,000 0,0252332 0,09412571 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,0252332 0,09398001 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,0252332 0,09383475 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0252332 0,09368994 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,0252332 0,09354558 ! protein deubiquitination GO:0016579 14 6 0,000 0,0252332 0,09340167 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,0252332 0,09325819 ! protein destabilization GO:0031648 9 6 0,000 0,0252332 0,09311516 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,0252332 0,09297256 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,0252332 0,0928304 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,0252332 0,09268868 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,0252332 0,09254738 ! progesterone metabolic process GO:0042448 10 6 0,000 0,0252332 0,09240652 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,0252332 0,09226608 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,0252332 0,09212607 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,0252332 0,09198649 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,0252332 0,09184733 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,0252332 0,09170858 ! determination of adult lifespan GO:0008340 15 6 0,000 0,0252332 0,09157026 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,0252332 0,09143235 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,0252332 0,09129486 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,0252332 0,09115778 ! catecholamine transport GO:0051937 9 6 0,000 0,0252332 0,09102111 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,0252332 0,09088486 ! sensory cilium assembly GO:0035058 10 6 0,000 0,0252332 0,090749 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,0252332 0,09061356 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,0252332 0,09047851 ! maternal placenta development GO:0001893 12 6 0,000 0,0252332 0,09034387 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,0252332 0,09020963 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,0252332 0,09007579 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,0252332 0,08994235 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,0252332 0,08980929 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,0252332 0,08967664 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,0252332 0,08954437 ! regulation of endocytosis GO:0030100 91 58 1,000 0,02537236 0,08990559 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,02537236 0,08977337 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,0270197 0,09546168 ! regulation of protein complex assembly GO:0043254 117 61 1,000 0,0278592 0,09828334 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 0,0278592 0,09813944 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,02870911 0,10098556 ! tRNA transcription GO:0009304 14 7 0,000 0,02937688 0,10318359 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02937688 0,10303318 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02937688 0,1028832 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02937688 0,10273366 ! regulation of helicase activity GO:0051095 15 7 0,000 0,02937688 0,10258456 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02937688 0,10243589 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02937688 0,10228764 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02937688 0,10213983 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02937688 0,10199244 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02937688 0,10184548 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02937688 0,10169894 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02937688 0,10155282 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02937688 0,10140712 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02937688 0,10126184 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02937688 0,10111697 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02937688 0,10097252 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02937688 0,10082848 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,02937688 0,10068485 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02937688 0,10054162 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02937688 0,10039881 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02937688 0,1002564 ! glycolipid transport GO:0046836 10 7 0,000 0,02937688 0,10011439 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02937688 0,09997279 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,02937688 0,09983158 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,02937688 0,09969078 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02937688 0,09955037 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02937688 0,09941035 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02937688 0,09927073 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02937688 0,0991315 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02937688 0,09899266 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02937688 0,09885421 ! mRNA stabilization GO:0048255 18 7 0,000 0,02937688 0,09871615 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02937688 0,09857847 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02937688 0,09844117 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02937688 0,09830426 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02937688 0,09816772 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02937688 0,09803157 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02937688 0,09789579 ! lipoprotein transport GO:0042953 14 7 0,000 0,02937688 0,09776039 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02937688 0,09762536 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02937688 0,09749071 ! rhythmic behavior GO:0007622 15 7 0,000 0,02937688 0,09735642 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02937688 0,09722251 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02937688 0,09708896 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02937688 0,09695578 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02937688 0,09682296 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02937688 0,09669051 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02937688 0,09655842 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02937688 0,09642669 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02937688 0,09629532 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02937688 0,0961643 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02937688 0,09603364 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02937688 0,09590334 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02937688 0,09577339 ! spinal cord patterning GO:0021511 13 7 0,000 0,02937688 0,09564379 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02937688 0,09551454 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02937688 0,09538564 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02937688 0,09525709 ! adrenal gland development GO:0030325 17 7 0,000 0,02937688 0,09512888 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02937688 0,09500102 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02937688 0,09487351 ! ovulation GO:0030728 9 7 0,000 0,02937688 0,09474633 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02937688 0,09461949 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02937688 0,094493 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02937688 0,09436684 ! microtubule nucleation GO:0007020 20 7 0,000 0,02937688 0,09424102 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02937688 0,09411553 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02937688 0,09399037 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02937688 0,09386555 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02937688 0,09374106 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02937688 0,0936169 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02937688 0,09349307 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02937688 0,09336957 ! galactose metabolic process GO:0006012 13 7 0,000 0,02937688 0,09324639 ! vesicle fusion GO:0006906 17 7 0,000 0,02937688 0,09312353 ! response to dietary excess GO:0002021 8 7 0,000 0,02937688 0,093001 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02937688 0,09287879 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02937688 0,0927569 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02937688 0,09263534 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02937688 0,09251409 ! organ growth GO:0035265 15 7 0,000 0,02937688 0,09239315 ! purine salvage GO:0043101 10 7 0,000 0,02937688 0,09227253 ! nucleoside transport GO:0015858 8 7 0,000 0,02937688 0,09215223 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02937688 0,09203224 ! parturition GO:0007567 14 7 0,000 0,02937688 0,09191256 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02937688 0,0917932 ! rRNA modification GO:0000154 14 7 0,000 0,02937688 0,09167414 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02937688 0,09155539 ! spindle checkpoint GO:0031577 15 7 0,000 0,02937688 0,09143695 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02937688 0,09131881 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02937688 0,09120098 ! macrophage differentiation GO:0030225 11 7 0,000 0,02937688 0,09108346 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02937688 0,09096623 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02937688 0,09084931 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,02937688 0,09073268 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02937688 0,09061636 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,02937688 0,09050033 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02937688 0,09038461 ! fibrinolysis GO:0042730 10 7 0,000 0,02937688 0,09026917 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02937688 0,09015403 ! eating behavior GO:0042755 7 7 0,000 0,02937688 0,09003919 ! B cell lineage commitment GO:0002326 21 7 0,000 0,02937688 0,08992463 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02937688 0,08981037 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02937688 0,0896964 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02937688 0,08958271 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02937688 0,08946932 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02937688 0,08935621 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02937688 0,08924339 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02937688 0,08913085 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02937688 0,08901859 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02937688 0,08890662 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02937688 0,08879493 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02937688 0,08868352 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02937688 0,08857238 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02937688 0,08846153 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02937688 0,08835095 ! regulation of meiosis GO:0040020 12 7 0,000 0,02937688 0,08824065 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02937688 0,08813063 ! T cell lineage commitment GO:0002360 16 7 0,000 0,02937688 0,08802087 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02937688 0,08791139 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02937688 0,08780219 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02937688 0,08769325 ! transcription termination GO:0006353 13 7 0,000 0,02937688 0,08758459 ! response to tumor cell GO:0002347 13 7 0,000 0,02937688 0,08747619 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,02937688 0,08736806 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02937688 0,0872602 ! anaphase GO:0051322 17 7 0,000 0,02937688 0,0871526 GO:0000090|mitotic anaphase, ! axonal fasciculation GO:0007413 18 7 0,000 0,02937688 0,08704527 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02937688 0,08693821 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02937688 0,0868314 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02937688 0,08672486 ! diuresis GO:0030146 12 7 0,000 0,02937688 0,08661858 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02937688 0,08651256 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02937688 0,0864068 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02937688 0,0863013 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02937688 0,08619605 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02937688 0,08609106 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02937688 0,08598633 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02937688 0,08588185 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02937688 0,08577762 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02937688 0,08567365 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02937688 0,08556993 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02937688 0,08546646 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02937688 0,08536324 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02937688 0,08526027 ! lymph node development GO:0048535 10 7 0,000 0,02937688 0,08515754 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02937688 0,08505507 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02937688 0,08495284 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02937688 0,08485085 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02937688 0,08474911 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02937688 0,08464762 ! adult feeding behavior GO:0008343 9 7 0,000 0,02937688 0,08454637 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02937688 0,08444535 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02937688 0,08434458 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02937688 0,08424405 ! muscle adaptation GO:0043500 14 7 0,000 0,02937688 0,08414376 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02937688 0,08404371 ! retina homeostasis GO:0001895 12 7 0,000 0,02937688 0,0839439 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02937688 0,08384432 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02937688 0,08374498 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02937688 0,08364587 ! protein prenylation GO:0018342 18 7 0,000 0,02937688 0,083547 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02937688 0,08344836 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02937688 0,08334995 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02937688 0,08325178 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,02956934 0,08369862 ! detection of external stimulus GO:0009581 91 63 1,000 0,02956934 0,08360026 ! myeloid cell differentiation GO:0030099 111 65 1,000 0,03132031 0,0884468 ! developmental maturation GO:0021700 116 66 1,000 0,03221087 0,09085503 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,03311133 0,09328554 ! lung development GO:0030324 144 67 1,000 0,03311133 0,09317643 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 1,000 0,03311133 0,09306758 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,03311133 0,09295899 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,03311133 0,09285064 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03350307 0,0938398 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03350307 0,09373068 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,03350307 0,09362182 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,03350307 0,09351321 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,03350307 0,09340485 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03350307 0,09329675 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03350307 0,09318889 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,03350307 0,09308128 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,03350307 0,09297392 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,03350307 0,09286681 ! meiotic prophase I GO:0007128 13 8 0,000 0,03350307 0,09275994 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03350307 0,09265332 ! oligopeptide transport GO:0006857 15 8 0,000 0,03350307 0,09254694 ! UTP metabolic process GO:0046051 8 8 0,000 0,03350307 0,09244081 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03350307 0,09233492 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03350307 0,09222928 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03350307 0,09212387 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03350307 0,09201871 ! succinate metabolic process GO:0006105 14 8 0,000 0,03350307 0,09191378 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03350307 0,0918091 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03350307 0,09170465 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03350307 0,09160044 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03350307 0,09149647 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,03350307 0,09139273 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03350307 0,09128923 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03350307 0,09118596 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03350307 0,09108293 ! reflex GO:0060004 16 8 0,000 0,03350307 0,09098012 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,03350307 0,09087755 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03350307 0,09077521 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03350307 0,0906731 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03350307 0,09057122 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,03350307 0,09046957 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03350307 0,09036815 ! pigment granule organization GO:0048753 16 8 0,000 0,03350307 0,09026695 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03350307 0,09016598 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03350307 0,09006524 ! astrocyte differentiation GO:0048708 18 8 0,000 0,03350307 0,08996472 ! histidine metabolic process GO:0006547 16 8 0,000 0,03350307 0,08986442 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03350307 0,08976435 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03350307 0,0896645 ! glycine catabolic process GO:0006546 13 8 0,000 0,03350307 0,08956488 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03350307 0,08946547 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,03350307 0,08936628 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,03350307 0,08926732 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,03350307 0,08916857 ! melanin metabolic process GO:0006582 15 8 0,000 0,03350307 0,08907004 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03350307 0,08897173 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03350307 0,08887364 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03350307 0,08877576 ! macrophage activation GO:0042116 12 8 0,000 0,03350307 0,0886781 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03350307 0,08858065 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03350307 0,08848341 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,03350307 0,08838639 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,03350307 0,08828958 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,03350307 0,08819299 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03350307 0,0880966 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,03350307 0,08800042 ! osteoblast development GO:0002076 16 8 0,000 0,03350307 0,08790446 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,03350307 0,0878087 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,03350307 0,08771315 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03350307 0,08761781 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,03350307 0,08752268 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,03350307 0,08742775 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03350307 0,08733303 ! response to UV-B GO:0010224 16 8 0,000 0,03350307 0,08723852 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03350307 0,0871442 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03350307 0,0870501 ! intermediate filament organization GO:0045109 12 8 0,000 0,03350307 0,08695619 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03350307 0,08686249 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,03350307 0,08676899 ! cellular extravasation GO:0045123 12 8 0,000 0,03350307 0,08667569 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03350307 0,08658259 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03350307 0,08648969 ! response to antibiotic GO:0046677 11 8 0,000 0,03350307 0,08639699 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03350307 0,08630448 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,03350307 0,08621218 ! DNA topological change GO:0006265 12 8 0,000 0,03350307 0,08612007 ! response to tropane GO:0014073 15 8 0,000 0,03350307 0,08602816 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,03350307 0,08593645 ! melanosome transport GO:0032402 13 8 0,000 0,03350307 0,08584493 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,03350307 0,08575361 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03350307 0,08566247 ! mast cell activation GO:0045576 14 8 0,000 0,03350307 0,08557154 ! multicellular organismal aging GO:0010259 18 8 0,000 0,03350307 0,08548079 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,03350307 0,08539024 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,03350307 0,08529988 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,03350307 0,08520971 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03350307 0,08511973 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03350307 0,08502995 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,03350307 0,08494035 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03350307 0,08485094 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03350307 0,08476171 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03350307 0,08467268 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03350307 0,08458383 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03350307 0,08449517 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03350307 0,08440669 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03350307 0,0843184 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,03350307 0,08423029 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03350307 0,08414237 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03350307 0,08405463 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03350307 0,08396707 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03350307 0,0838797 ! hormone catabolic process GO:0042447 17 8 0,000 0,03350307 0,0837925 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03350307 0,08370549 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,03350307 0,08361866 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,03350307 0,08353201 ! ATP catabolic process GO:0006200 11 8 0,000 0,03350307 0,08344554 ! blastocyst growth GO:0001832 19 8 0,000 0,03350307 0,08335924 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03350307 0,08327313 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03350307 0,08318719 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03350307 0,08310143 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03350307 0,08301585 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03350307 0,08293044 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,03350307 0,08284521 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,03350307 0,08276015 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03350307 0,08267527 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03350307 0,08259056 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03350307 0,08250603 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,03350307 0,08242167 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03350307 0,08233748 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,03350307 0,08225346 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03350307 0,08216961 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03350307 0,08208594 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03350307 0,08200243 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03350307 0,08191909 ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,0340216 0,0831025 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of lipase activity GO:0060191 130 68 1,000 0,0340216 0,08301822 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,0340216 0,08293411 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,0340216 0,08285017 ! urogenital system development GO:0001655 137 69 1,000 0,03494158 0,0850045 ! respiratory tube development GO:0030323 150 70 1,000 0,03587118 0,08717784 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,0368103 0,0893699 ! regulation of developmental growth GO:0048638 15 9 0,000 0,03761186 0,09122393 ! axon extension GO:0048675 15 9 0,000 0,03761186 0,09113207 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,03761186 0,09104038 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,03761186 0,09094889 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,03761186 0,09085757 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03761186 0,09076644 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,03761186 0,09067549 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,03761186 0,09058473 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,03761186 0,09049414 ! phosphate transport GO:0006817 19 9 0,000 0,03761186 0,09040374 ! reproductive behavior GO:0019098 19 9 0,000 0,03761186 0,09031351 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03761186 0,09022347 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,03761186 0,09013361 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03761186 0,09004392 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,03761186 0,08995442 ! GTP metabolic process GO:0046039 9 9 0,000 0,03761186 0,08986509 ! RNA methylation GO:0001510 15 9 0,000 0,03761186 0,08977593 ! elastic fiber assembly GO:0048251 15 9 0,000 0,03761186 0,08968696 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,03761186 0,08959816 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,03761186 0,08950954 ! artery development GO:0060840 24 9 0,000 0,03761186 0,08942109 GO:0048844|artery morphogenesis, ! regulation of glycolysis GO:0006110 21 9 0,000 0,03761186 0,08933281 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,03761186 0,08924472 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,03761186 0,08915679 ! chemosensory behavior GO:0007635 20 9 0,000 0,03761186 0,08906904 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,03761186 0,08898146 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03761186 0,08889405 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,03761186 0,08880681 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,03761186 0,08871975 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,03761186 0,08863285 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03761186 0,08854613 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03761186 0,08845957 ! protein targeting to ER GO:0045047 22 9 0,000 0,03761186 0,08837319 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,03761186 0,08828697 ! T cell selection GO:0045058 23 9 0,000 0,03761186 0,08820092 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,03761186 0,08811504 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03761186 0,08802932 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,03761186 0,08794377 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03761186 0,08785839 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03761186 0,08777317 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03761186 0,08768812 ! mannose metabolic process GO:0006013 13 9 0,000 0,03761186 0,08760323 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,03761186 0,08751851 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,03761186 0,08743395 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,03761186 0,08734956 ! receptor clustering GO:0043113 18 9 0,000 0,03761186 0,08726532 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,03761186 0,08718125 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03761186 0,08709735 ! ruffle organization GO:0031529 15 9 0,000 0,03761186 0,0870136 ! retinol metabolic process GO:0042572 18 9 0,000 0,03761186 0,08693001 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,03761186 0,08684659 ! behavioral fear response GO:0001662 22 9 0,000 0,03761186 0,08676332 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,03761186 0,08668021 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,03761186 0,08659726 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,03761186 0,08651448 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,03761186 0,08643184 ! oligodendrocyte development GO:0014003 10 9 0,000 0,03761186 0,08634937 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,03761186 0,08626706 ! segment specification GO:0007379 13 9 0,000 0,03761186 0,0861849 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03761186 0,08610289 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,03761186 0,08602105 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03761186 0,08593936 ! response to amine stimulus GO:0014075 13 9 0,000 0,03761186 0,08585782 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03761186 0,08577644 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,03761186 0,08569521 ! erythrocyte development GO:0048821 15 9 0,000 0,03761186 0,08561414 ! gas homeostasis GO:0033483 16 9 0,000 0,03761186 0,08553322 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03761186 0,08545245 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,03761186 0,08537183 ! renal water homeostasis GO:0003091 14 9 0,000 0,03761186 0,08529137 ! postreplication repair GO:0006301 22 9 0,000 0,03761186 0,08521106 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,03761186 0,0851309 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,03761186 0,08505088 ! icosanoid secretion GO:0032309 15 9 0,000 0,03761186 0,08497102 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,03761186 0,08489131 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03761186 0,08481175 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,03761186 0,08473234 ! regulation of cell division GO:0051302 15 9 0,000 0,03761186 0,08465308 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,03761186 0,08457396 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,03761186 0,084495 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03761186 0,08441618 ! sterol catabolic process GO:0016127 11 9 0,000 0,03761186 0,0843375 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03761186 0,08425898 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,03761186 0,0841806 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,03761186 0,08410236 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,03761186 0,08402427 GO:0000084|S phase of mitotic cell cycle, ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,03761186 0,08394633 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03761186 0,08386853 ! purine base metabolic process GO:0006144 21 9 0,000 0,03761186 0,08379087 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,03761186 0,08371336 ! pigment granule transport GO:0051904 17 9 0,000 0,03761186 0,08363599 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,03761186 0,08355876 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,03761186 0,08348168 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,03761186 0,08340474 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03761186 0,08332794 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03761186 0,08325128 ! mitochondrion localization GO:0051646 15 9 0,000 0,03761186 0,08317476 ! regulation of caspase activity GO:0043281 122 72 1,000 0,03775883 0,0834231 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,03775883 0,08334657 ! respiratory system development GO:0060541 153 72 1,000 0,03775883 0,08327017 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,03968379 0,08743517 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,04066002 0,08950413 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,04066002 0,08942232 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,04066002 0,08934065 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04170332 0,09154945 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,04170332 0,09146599 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04170332 0,09138269 ! synapsis GO:0007129 13 10 0,000 0,04170332 0,09129954 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,04170332 0,09121654 ! N-glycan processing GO:0006491 20 10 0,000 0,04170332 0,09113369 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,04170332 0,09105099 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,04170332 0,09096844 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04170332 0,09088605 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,04170332 0,0908038 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,04170332 0,09072169 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,04170332 0,09063974 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,04170332 0,09055794 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,04170332 0,09047628 ! androgen metabolic process GO:0008209 17 10 0,000 0,04170332 0,09039477 ! phospholipid efflux GO:0033700 16 10 0,000 0,04170332 0,09031341 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,04170332 0,09023219 ! lung alveolus development GO:0048286 26 10 0,000 0,04170332 0,09015112 ! pathogenesis GO:0009405 13 10 0,000 0,04170332 0,09007019 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04170332 0,08998941 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,04170332 0,08990878 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,04170332 0,08982829 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,04170332 0,08974794 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,04170332 0,08966773 ! endoderm development GO:0007492 16 10 0,000 0,04170332 0,08958767 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,04170332 0,08950776 ! arginine catabolic process GO:0006527 13 10 0,000 0,04170332 0,08942798 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04170332 0,08934835 ! proline metabolic process GO:0006560 13 10 0,000 0,04170332 0,08926886 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04170332 0,08918951 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,04170332 0,0891103 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,04170332 0,08903123 ! V(D)J recombination GO:0033151 28 10 0,000 0,04170332 0,0889523 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04170332 0,08887351 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,04170332 0,08879486 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,04170332 0,08871635 ! B cell proliferation GO:0042100 18 10 0,000 0,04170332 0,08863798 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,04170332 0,08855975 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,04170332 0,08848165 ! multicellular organism growth GO:0035264 18 10 0,000 0,04170332 0,0884037 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,04170332 0,08832588 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,04170332 0,08824819 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,04170332 0,08817065 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04170332 0,08809323 ! macroautophagy GO:0016236 17 10 0,000 0,04170332 0,08801596 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,04170332 0,08793882 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,04170332 0,08786182 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,04170332 0,08778495 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,04170332 0,08770821 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,04170332 0,08763161 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04170332 0,08755514 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04170332 0,08747881 ! brain morphogenesis GO:0048854 23 10 0,000 0,04170332 0,08740261 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,04170332 0,08732654 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,04170332 0,0872506 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,04170332 0,0871748 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,04170332 0,08709913 ! blastoderm segmentation GO:0007350 18 10 0,000 0,04170332 0,08702359 ! response to dsRNA GO:0043331 20 10 0,000 0,04170332 0,08694818 ! DNA ligation GO:0006266 19 10 0,000 0,04170332 0,0868729 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04170332 0,08679775 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04170332 0,08672273 ! melanosome localization GO:0032400 16 10 0,000 0,04170332 0,08664784 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,04170332 0,08657308 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,04170332 0,08649844 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04170332 0,08642394 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,04170332 0,08634957 ! mRNA cleavage GO:0006379 17 10 0,000 0,04170332 0,08627532 ! protein sumoylation GO:0016925 15 10 0,000 0,04170332 0,0862012 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04170332 0,08612721 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04170332 0,08605334 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04170332 0,0859796 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,04170332 0,08590599 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,04170332 0,0858325 ! salivary gland development GO:0007431 27 10 0,000 0,04170332 0,08575914 ! prophase GO:0051324 15 10 0,000 0,04170332 0,0856859 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04170332 0,08561279 ! apical protein localization GO:0045176 15 10 0,000 0,04170332 0,08553981 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,04170332 0,08546695 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,04170332 0,08539421 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,04170332 0,08532159 ! midbrain development GO:0030901 13 10 0,000 0,04170332 0,0852491 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04170332 0,08517674 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,04170332 0,08510449 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,04170332 0,08503237 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,04170332 0,08496037 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04170332 0,08488849 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,04170332 0,08481673 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,04170332 0,0847451 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,04170332 0,08467358 ! oocyte development GO:0048599 17 10 0,000 0,04170332 0,08460219 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04170332 0,08453091 ! cerebellar cortex development GO:0021695 15 10 0,000 0,04170332 0,08445976 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,04170332 0,08438873 ! activation of innate immune response GO:0002218 12 10 0,000 0,04170332 0,08431781 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,04170332 0,08424701 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,04170332 0,08417634 ! response to nicotine GO:0035094 20 10 0,000 0,04170332 0,08410578 ! establishment of cell polarity GO:0030010 16 10 0,000 0,04170332 0,08403534 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,04170332 0,08396502 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04170332 0,08389481 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,04263952 0,0857065 ! blood coagulation GO:0007596 146 78 1,000 0,0436426 0,08764949 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,0436426 0,08757639 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,0436426 0,08750341 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,04465444 0,08945761 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,04465444 0,08938319 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,04465444 0,08930889 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,04465444 0,08923471 ! muscle cell differentiation GO:0042692 159 80 1,000 0,04567496 0,0911983 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,04577752 0,0913273 ! respiratory burst GO:0045730 17 11 0,000 0,04577752 0,09125163 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,04577752 0,09117609 ! neuron fate specification GO:0048665 17 11 0,000 0,04577752 0,09110068 ! telencephalon cell migration GO:0022029 20 11 0,000 0,04577752 0,09102539 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,04577752 0,09095023 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,04577752 0,09087518 ! thyroid gland development GO:0030878 26 11 0,000 0,04577752 0,09080027 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,04577752 0,09072547 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,04577752 0,0906508 ! response to pain GO:0048265 24 11 0,000 0,04577752 0,09057625 ! T cell proliferation GO:0042098 26 11 0,000 0,04577752 0,09050183 ! blood vessel remodeling GO:0001974 29 11 0,000 0,04577752 0,09042752 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,04577752 0,09035334 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,04577752 0,09027928 ! bone resorption GO:0045453 16 11 0,000 0,04577752 0,09020534 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,04577752 0,09013152 ! ventral spinal cord development GO:0021517 21 11 0,000 0,04577752 0,09005783 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04577752 0,08998425 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04577752 0,08991079 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,04577752 0,08983746 ! melanocyte differentiation GO:0030318 21 11 0,000 0,04577752 0,08976424 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,04577752 0,08969114 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,04577752 0,08961816 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,04577752 0,0895453 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,04577752 0,08947256 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,04577752 0,08939994 ! lipid digestion GO:0044241 18 11 0,000 0,04577752 0,08932743 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,04577752 0,08925504 ! UV protection GO:0009650 19 11 0,000 0,04577752 0,08918277 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,04577752 0,08911062 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04577752 0,08903858 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,04577752 0,08896666 ! negative regulation of ossification GO:0030279 26 11 0,000 0,04577752 0,08889485 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,04577752 0,08882316 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,04577752 0,08875159 ! regulation of organ growth GO:0046620 13 11 0,000 0,04577752 0,08868013 ! pigment granule localization GO:0051875 20 11 0,000 0,04577752 0,08860879 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,04577752 0,08853756 ! vasoconstriction GO:0042310 18 11 0,000 0,04577752 0,08846644 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04577752 0,08839544 ! embryonic axis specification GO:0000578 18 11 0,000 0,04577752 0,08832456 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,04577752 0,08825378 ! snRNA metabolic process GO:0016073 24 11 0,000 0,04577752 0,08818312 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04577752 0,08811258 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,04577752 0,08804214 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04577752 0,08797182 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,04577752 0,08790161 ! zymogen activation GO:0031638 15 11 0,000 0,04577752 0,08783152 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,04577752 0,08776153 ! nucleosome positioning GO:0016584 15 11 0,000 0,04577752 0,08769166 ! regulation of isotype switching GO:0045191 22 11 0,000 0,04577752 0,0876219 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,04577752 0,08755224 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,04577752 0,0874827 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,04577752 0,08741327 ! acid secretion GO:0046717 18 11 0,000 0,04577752 0,08734395 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04577752 0,08727474 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,04577752 0,08720564 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,04577752 0,08713665 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,04577752 0,08706776 ! oocyte differentiation GO:0009994 18 11 0,000 0,04577752 0,08699899 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,04577752 0,08693033 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,04577752 0,08686177 ! cholesterol efflux GO:0033344 19 11 0,000 0,04577752 0,08679332 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,04577752 0,08672498 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04577752 0,08665674 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,04577752 0,08658862 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,04577752 0,0865206 ! embryonic gut development GO:0048566 15 11 0,000 0,04577752 0,08645269 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,04577752 0,08638488 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,04577752 0,08631718 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,04577752 0,08624959 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,04577752 0,0861821 ! defense response to fungus GO:0050832 13 11 0,000 0,04577752 0,08611472 ! developmental induction GO:0031128 19 11 0,000 0,04577752 0,08604744 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,04577752 0,08598027 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04577752 0,0859132 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,04577752 0,08584624 ! sequestering of metal ion GO:0051238 14 11 0,000 0,04577752 0,08577938 ! lamellipodium assembly GO:0030032 20 11 0,000 0,04577752 0,08571262 ! regulation of embryonic development GO:0045995 27 11 0,000 0,04577752 0,08564597 ! nucleus localization GO:0051647 19 11 0,000 0,04577752 0,08557943 ! regulation of synapse organization GO:0050807 17 11 0,000 0,04577752 0,08551298 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,04670406 0,08717608 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 0,04670406 0,08710851 ! digestion GO:0007586 112 81 1,000 0,04670406 0,08704103 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,04670406 0,08697366 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,04774166 0,08883714 ! response to oxygen levels GO:0070482 176 83 1,000 0,04878765 0,09071336 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,04983454 0,09258834 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,04983454 0,0925169 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,04983454 0,09244557 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,04983454 0,09237434 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,04983454 0,09230323 ! virus-host interaction GO:0019048 29 12 0,000 0,04983454 0,09223223 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,04983454 0,09216134 ! cartilage condensation GO:0001502 20 12 0,000 0,04983454 0,09209055 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,04983454 0,09201988 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,04983454 0,09194931 ! protein complex disassembly GO:0043241 27 12 0,000 0,04983454 0,09187885 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04983454 0,0918085 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,04983454 0,09173826 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,04983454 0,09166812 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,04983454 0,09159809 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,04983454 0,09152817 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,04983454 0,09145835 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,04983454 0,09138864 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,04983454 0,09131904 ! drug transport GO:0015893 16 12 0,000 0,04983454 0,09124954 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,04983454 0,09118015 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,04983454 0,09111087 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,04983454 0,09104169 ! polyamine metabolic process GO:0006595 17 12 0,000 0,04983454 0,09097261 ! mitotic spindle organization GO:0007052 21 12 0,000 0,04983454 0,09090364 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,04983454 0,09083477 ! forebrain cell migration GO:0021885 21 12 0,000 0,04983454 0,09076601 ! asymmetric protein localization GO:0008105 20 12 0,000 0,04983454 0,09069735 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,04983454 0,0906288 ! entry into host cell GO:0030260 32 12 0,000 0,04983454 0,09056035 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,04983454 0,090492 ! monoamine transport GO:0015844 18 12 0,000 0,04983454 0,09042376 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04983454 0,09035561 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,04983454 0,09028757 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,04983454 0,09021964 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,04983454 0,0901518 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04983454 0,09008407 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,04983454 0,09001644 ! protein homotetramerization GO:0051289 21 12 0,000 0,04983454 0,08994891 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,04983454 0,08988148 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04983454 0,08981416 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,04983454 0,08974693 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,04983454 0,08967981 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04983454 0,08961278 ! cranial nerve development GO:0021545 20 12 0,000 0,04983454 0,08954585 ! fucose catabolic process GO:0019317 22 12 0,000 0,04983454 0,08947903 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,04983454 0,0894123 ! histone acetylation GO:0016573 26 12 0,000 0,04983454 0,08934568 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,04983454 0,08927915 ! autonomic nervous system development GO:0048483 24 12 0,000 0,04983454 0,08921272 ! gland morphogenesis GO:0022612 29 12 0,000 0,04983454 0,08914639 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,04983454 0,08908016 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,04983454 0,08901403 ! T cell homeostasis GO:0043029 25 12 0,000 0,04983454 0,088948 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,04983454 0,08888206 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,04983454 0,08881622 ! spleen development GO:0048536 22 12 0,000 0,04983454 0,08875048 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,04983454 0,08868484 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,04983454 0,08861929 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,04983454 0,08855384 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,04983454 0,08848849 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,04983454 0,08842323 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,04983454 0,08835807 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,04983454 0,088293 ! response to cold GO:0009409 17 12 0,000 0,04983454 0,08822803 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,04983454 0,08816316 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,04983454 0,08809838 ! hemostasis GO:0007599 158 84 1,000 0,04984196 0,08804682 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,04984196 0,08798222 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,0509045 0,08979196 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,0509045 0,08972617 GO:0002696|positive regulation of leukocyte activation, ! tube morphogenesis GO:0035239 176 86 1,000 0,05197518 0,09154632 ! regulation of protein transport GO:0051223 154 87 1,000 0,0530539 0,09337797 GO:0070201|regulation of establishment of protein localization, ! cGMP metabolic process GO:0046068 18 13 0,000 0,05387444 0,09475285 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,05387444 0,09468364 ! regulation of chemokine production GO:0032642 18 13 0,000 0,05387444 0,09461452 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05387444 0,09454551 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,05387444 0,0944766 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,05387444 0,09440779 ! lipid localization GO:0010876 28 13 0,000 0,05387444 0,09433908 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,05387444 0,09427047 ! organelle fusion GO:0048284 32 13 0,000 0,05387444 0,09420196 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,05387444 0,09413355 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,05387444 0,09406524 ! endocrine pancreas development GO:0031018 22 13 0,000 0,05387444 0,09399703 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,05387444 0,09392891 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,05387444 0,0938609 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,05387444 0,09379298 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05387444 0,09372516 ! methionine metabolic process GO:0006555 27 13 0,000 0,05387444 0,09365744 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,05387444 0,09358982 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,05387444 0,09352229 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,05387444 0,09345487 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,05387444 0,09338753 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,05387444 0,0933203 ! response to X-ray GO:0010165 25 13 0,000 0,05387444 0,09325316 ! cytokine metabolic process GO:0042107 22 13 0,000 0,05387444 0,09318612 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,05387444 0,09311918 ! exocrine system development GO:0035272 32 13 0,000 0,05387444 0,09305233 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,05387444 0,09298558 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,05387444 0,09291892 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,05387444 0,09285236 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,05387444 0,0927859 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,05387444 0,09271953 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,05387444 0,09265325 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,05387444 0,09258707 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,05387444 0,09252098 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,05387444 0,09245499 ! regulation of cellular pH GO:0030641 22 13 0,000 0,05387444 0,09238909 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05387444 0,09232329 ! ribosome assembly GO:0042255 17 13 0,000 0,05387444 0,09225758 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,05387444 0,09219196 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,05387444 0,09212644 ! chromatin silencing GO:0006342 26 13 0,000 0,05387444 0,09206101 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,05387444 0,09199567 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05387444 0,09193042 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05387444 0,09186527 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,05387444 0,09180021 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,05387444 0,09173524 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,05387444 0,09167037 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05387444 0,09160558 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,05387444 0,09154089 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,05387444 0,09147629 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,05387444 0,09141178 ! embryonic placenta development GO:0001892 23 13 0,000 0,05387444 0,09134736 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,05387444 0,09128303 ! insulin secretion GO:0030073 23 13 0,000 0,05387444 0,09121879 ! actin filament polymerization GO:0030041 24 13 0,000 0,05387444 0,09115464 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,05387444 0,09109058 ! acrosome reaction GO:0007340 18 13 0,000 0,05387444 0,09102661 ! cellular respiration GO:0045333 135 88 1,000 0,05414059 0,09141212 ! positive regulation of protein modification process GO:0031401 136 88 1,000 0,05414059 0,09134801 ! regulation of neurological system process GO:0031644 148 88 1,000 0,05414059 0,091284 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,05523516 0,09306429 ! ossification GO:0001503 188 90 1,000 0,05633753 0,0948552 ! bone development GO:0060348 189 91 1,000 0,0574476 0,09665659 ! rRNA transcription GO:0009303 25 14 0,000 0,05789729 0,09734514 ! lactation GO:0007595 26 14 0,000 0,05789729 0,09727716 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,05789729 0,09720927 ! reproductive cellular process GO:0048610 20 14 0,000 0,05789729 0,09714149 ! tRNA modification GO:0006400 20 14 0,000 0,05789729 0,09707379 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,05789729 0,09700619 ! regulation of S phase GO:0033261 23 14 0,000 0,05789729 0,09693869 ! water transport GO:0006833 21 14 0,000 0,05789729 0,09687127 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,05789729 0,09680395 ! non-recombinational repair GO:0000726 25 14 0,000 0,05789729 0,09673673 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,05789729 0,0966696 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,05789729 0,09660256 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,05789729 0,09653561 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,05789729 0,09646876 ! RNA polyadenylation GO:0043631 30 14 0,000 0,05789729 0,096402 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,05789729 0,09633533 ! palate development GO:0060021 31 14 0,000 0,05789729 0,09626876 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,05789729 0,09620227 ! regulated secretory pathway GO:0045055 23 14 0,000 0,05789729 0,09613588 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,05789729 0,09606958 ! arginine metabolic process GO:0006525 17 14 0,000 0,05789729 0,09600337 ! regulation of heart rate GO:0002027 24 14 0,000 0,05789729 0,09593725 ! organic alcohol transport GO:0015850 29 14 0,000 0,05789729 0,09587123 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,05789729 0,09580529 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,05789729 0,09573944 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,05789729 0,09567369 ! neutral amino acid transport GO:0015804 26 14 0,000 0,05789729 0,09560802 ! L-amino acid transport GO:0015807 30 14 0,000 0,05789729 0,09554245 ! bone mineralization GO:0030282 17 14 0,000 0,05789729 0,09547696 ! stem cell development GO:0048864 43 14 0,000 0,05789729 0,09541157 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,05789729 0,09534626 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,05789729 0,09528105 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,05789729 0,09521592 ! cerebellum development GO:0021549 21 14 0,000 0,05789729 0,09515088 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,05789729 0,09508593 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,05789729 0,09502107 ! response to gamma radiation GO:0010332 28 14 0,000 0,05789729 0,0949563 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,05789729 0,09489161 ! cofactor transport GO:0051181 26 14 0,000 0,05789729 0,09482702 ! NADP metabolic process GO:0006739 24 14 0,000 0,05789729 0,09476251 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,05789729 0,09469809 ! intestinal absorption GO:0050892 25 14 0,000 0,05789729 0,09463376 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,05789729 0,09456951 ! oxygen transport GO:0015671 21 14 0,000 0,05789729 0,09450535 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05789729 0,09444128 ! male genitalia development GO:0030539 24 14 0,000 0,05789729 0,0943773 ! regulation of RNA stability GO:0043487 32 14 0,000 0,05789729 0,0943134 ! regulation of axon extension GO:0030516 37 14 0,000 0,05789729 0,09424959 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,05789729 0,09418586 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,05969053 0,09703744 GO:0010498|proteasomal protein catabolic process, ! regulation of membrane potential GO:0042391 164 93 1,000 0,05969053 0,09697192 ! transcription initiation GO:0006352 153 94 1,000 0,06082322 0,09874539 ! regulation of T cell activation GO:0050863 158 94 1,000 0,06082322 0,09867881 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,06190318 0,10036324 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06190318 0,10029566 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,06190318 0,10022816 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,06190318 0,10016076 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,06190318 0,10009345 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,06190318 0,10002623 ! copper ion transport GO:0006825 20 15 0,000 0,06190318 0,09995909 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,06190318 0,09989205 ! sulfate transport GO:0008272 23 15 0,000 0,06190318 0,0998251 ! response to cAMP GO:0051591 22 15 0,000 0,06190318 0,09975824 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,06190318 0,09969147 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,06190318 0,09962478 ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,06190318 0,09955819 ! response to hexose stimulus GO:0009746 22 15 0,000 0,06190318 0,09949168 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,06190318 0,09942527 ! pituitary gland development GO:0021983 29 15 0,000 0,06190318 0,09935894 ! vesicle coating GO:0006901 33 15 0,000 0,06190318 0,0992927 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,06190318 0,09922655 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,06190318 0,09916049 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,06190318 0,09909451 ! regulation of exocytosis GO:0017157 22 15 0,000 0,06190318 0,09902862 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,06190318 0,09896282 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,06190318 0,09889711 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,06190318 0,09883149 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,06190318 0,09876595 ! regulation of vasodilation GO:0042312 26 15 0,000 0,06190318 0,0987005 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,06190318 0,09863513 ! histone deacetylation GO:0016575 20 15 0,000 0,06190318 0,09856985 ! mRNA splice site selection GO:0006376 38 15 0,000 0,06190318 0,09850466 ! tissue regeneration GO:0042246 26 15 0,000 0,06190318 0,09843956 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,06190318 0,09837454 ! water homeostasis GO:0030104 27 15 0,000 0,06190318 0,0983096 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,06190318 0,09824476 ! muscle maintenance GO:0046716 26 15 0,000 0,06190318 0,09817999 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,06190318 0,09811532 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,06190318 0,09805072 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,06190318 0,09798622 ! dopamine metabolic process GO:0042417 35 15 0,000 0,06190318 0,09792179 ! heme biosynthetic process GO:0006783 29 15 0,000 0,06190318 0,09785746 ! cell killing GO:0001906 29 15 0,000 0,06190318 0,0977932 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,06190318 0,09772903 ! detection of bacterium GO:0016045 18 15 0,000 0,06190318 0,09766495 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,06190318 0,09760095 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,06190318 0,09753703 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,06190318 0,0974732 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,06190318 0,09740945 ! peptide hormone processing GO:0016486 23 15 0,000 0,06190318 0,09734578 ! forebrain development GO:0030900 188 95 1,000 0,06196329 0,09737666 ! protein ubiquitination GO:0016567 217 97 1,000 0,06426522 0,10092828 ! hormone metabolic process GO:0042445 157 97 1,000 0,06426522 0,10086244 ! regulation of protein localization GO:0032880 176 97 1,000 0,06426522 0,10079669 ! response to virus GO:0009615 160 98 1,000 0,06542692 0,10255191 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,06589216 0,1032139 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,06589216 0,10314674 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,06589216 0,10307968 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,06589216 0,1030127 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,06589216 0,10294581 ! bone remodeling GO:0046849 27 16 0,000 0,06589216 0,102879 ! filopodium assembly GO:0046847 32 16 0,000 0,06589216 0,10281229 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,06589216 0,10274565 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,06589216 0,10267911 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,06589216 0,10261265 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,06589216 0,10254628 ! startle response GO:0001964 28 16 0,000 0,06589216 0,10247999 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,06589216 0,10241379 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,06589216 0,10234767 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,06589216 0,10228164 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,06589216 0,1022157 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,06589216 0,10214984 ! protein polyubiquitination GO:0000209 34 16 0,000 0,06589216 0,10208406 ! glutamate metabolic process GO:0006536 22 16 0,000 0,06589216 0,10201837 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,06589216 0,10195276 ! response to osmotic stress GO:0006970 25 16 0,000 0,06589216 0,10188724 ! lysosomal transport GO:0007041 26 16 0,000 0,06589216 0,1018218 ! fructose metabolic process GO:0006000 25 16 0,000 0,06589216 0,10175645 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06589216 0,10169118 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06589216 0,10162599 ! intermediate filament-based process GO:0045103 32 16 0,000 0,06589216 0,10156089 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,06589216 0,10149587 ! negative regulation of immune response GO:0050777 35 16 0,000 0,06589216 0,10143093 ! axon cargo transport GO:0008088 43 16 0,000 0,06589216 0,10136608 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,06589216 0,10130131 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,06589216 0,10123662 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,06589216 0,10117201 ! DNA replication initiation GO:0006270 27 16 0,000 0,06589216 0,10110749 ! neuron recognition GO:0008038 35 16 0,000 0,06589216 0,10104305 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,06589216 0,10097869 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,06589216 0,10091441 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,06589216 0,10085022 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,06589216 0,10078611 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,06589216 0,10072207 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,06589216 0,10065812 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,06589216 0,10059425 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,06589216 0,10053047 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06589216 0,10046676 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,06589216 0,10040313 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,06589216 0,10033959 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,06589216 0,10027612 ! defense response to virus GO:0051607 37 16 0,000 0,06589216 0,10021273 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,06659567 0,10121869 GO:0060538|skeletal muscle organ development, ! positive regulation of cell killing GO:0031343 32 17 0,000 0,06986432 0,10611966 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,06986432 0,10605271 ! metencephalon development GO:0022037 30 17 0,000 0,06986432 0,10598584 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,06986432 0,10591906 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,06986432 0,10585236 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,06986432 0,10578574 ! signal complex assembly GO:0007172 41 17 0,000 0,06986432 0,10571921 ! endothelial cell migration GO:0043542 28 17 0,000 0,06986432 0,10565276 ! inositol metabolic process GO:0006020 28 17 0,000 0,06986432 0,1055864 ! gene silencing by RNA GO:0031047 36 17 0,000 0,06986432 0,10552012 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,06986432 0,10545392 ! glial cell development GO:0021782 27 17 0,000 0,06986432 0,1053878 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,06986432 0,10532177 ! adult walking behavior GO:0007628 33 17 0,000 0,06986432 0,10525582 ! heart looping GO:0001947 30 17 0,000 0,06986432 0,10518995 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,06986432 0,10512417 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,06986432 0,10505847 ! myoblast differentiation GO:0045445 45 17 0,000 0,06986432 0,10499285 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,06986432 0,10492731 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,06986432 0,10486185 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,06986432 0,10479648 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,06986432 0,10473118 ! glycine metabolic process GO:0006544 28 17 0,000 0,06986432 0,10466597 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,06986432 0,10460084 ! NAD metabolic process GO:0019674 29 17 0,000 0,06986432 0,10453579 ! membrane budding GO:0006900 37 17 0,000 0,06986432 0,10447082 ! DNA integration GO:0015074 29 17 0,000 0,06986432 0,10440593 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,06986432 0,10434112 ! regulation of protein binding GO:0043393 33 17 0,000 0,06986432 0,10427639 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,06986432 0,10421175 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,06986432 0,10414718 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,06986432 0,10408269 ! genitalia development GO:0048806 30 17 0,000 0,06986432 0,10401828 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,06986432 0,10395396 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,06986432 0,10388971 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,06986432 0,10382554 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,06986432 0,10376145 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,06986432 0,10369744 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,06986432 0,10363351 ! steroid catabolic process GO:0006706 31 17 0,000 0,06986432 0,10356965 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,06986432 0,10350588 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,06986432 0,10344218 ! gas transport GO:0015669 25 17 0,000 0,06986432 0,10337856 ! organic cation transport GO:0015695 31 17 0,000 0,06986432 0,10331503 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,06986432 0,10325156 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,06986432 0,10318818 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,06986432 0,10312488 ! microspike assembly GO:0030035 36 17 0,000 0,06986432 0,10306165 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,06986432 0,1029985 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,07381971 0,10876315 ! neuron maturation GO:0042551 42 18 0,000 0,07381971 0,10869659 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,07381971 0,10863011 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,07381971 0,10856371 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,07381971 0,10849739 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,07381971 0,10843115 ! memory GO:0007613 31 18 0,000 0,07381971 0,10836499 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,07381971 0,10829892 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,07381971 0,10823292 ! patterning of blood vessels GO:0001569 39 18 0,000 0,07381971 0,10816701 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,07381971 0,10810117 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,07381971 0,10803542 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,07381971 0,10796974 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,07381971 0,10790415 ! glutamine metabolic process GO:0006541 29 18 0,000 0,07381971 0,10783863 ! response to retinoic acid GO:0032526 26 18 0,000 0,07381971 0,10777319 ! response to fungus GO:0009620 21 18 0,000 0,07381971 0,10770784 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,07381971 0,10764256 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,07381971 0,10757736 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,07381971 0,10751224 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,07381971 0,1074472 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,07381971 0,10738224 ! vitamin transport GO:0051180 27 18 0,000 0,07381971 0,10731736 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,07381971 0,10725255 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,07381971 0,10718782 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,07381971 0,10712318 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,07381971 0,1070586 ! nerve development GO:0021675 28 18 0,000 0,07381971 0,10699411 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,07381971 0,1069297 ! protein secretion GO:0009306 39 19 0,000 0,07775842 0,11256724 ! positive regulation of translation GO:0045727 30 19 0,000 0,07775842 0,11249955 ! negative regulation of defense response GO:0031348 25 19 0,000 0,07775842 0,11243194 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,07775842 0,11236441 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,07775842 0,11229697 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,07775842 0,1122296 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,07775842 0,11216232 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,07775842 0,11209512 ! bile acid metabolic process GO:0008206 29 19 0,000 0,07775842 0,11202799 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,07775842 0,11196095 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,07775842 0,11189399 ! cerebral cortex development GO:0021987 36 19 0,000 0,07775842 0,11182711 ! pigmentation during development GO:0048066 41 19 0,000 0,07775842 0,1117603 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,07775842 0,11169358 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,07775842 0,11162694 ! heme metabolic process GO:0042168 36 19 0,000 0,07775842 0,11156038 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,07775842 0,11149389 ! plasma membrane fusion GO:0045026 28 19 0,000 0,07775842 0,11142749 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,07775842 0,11136116 ! peptide cross-linking GO:0018149 37 19 0,000 0,07775842 0,11129491 ! protein export from nucleus GO:0006611 36 19 0,000 0,07775842 0,11122875 ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,07775842 0,11116266 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,07775842 0,11109664 ! visual learning GO:0008542 36 19 0,000 0,07775842 0,11103071 ! cellular pigmentation GO:0033059 36 19 0,000 0,07775842 0,11096486 ! G1 phase GO:0051318 40 19 0,000 0,07775842 0,11089908 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,07775842 0,11083338 ! cell-cell junction organization GO:0045216 35 19 0,000 0,07775842 0,11076776 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,07775842 0,11070222 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,07775842 0,11063675 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,07775842 0,11057136 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,07775842 0,11050605 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,07775842 0,11044082 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,07775842 0,11037566 ! cilium assembly GO:0042384 37 19 0,000 0,07775842 0,11031058 ! peptide hormone secretion GO:0030072 31 19 0,000 0,07775842 0,11024558 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,0816805 0,1157381 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,0816805 0,11566997 ! positive regulation of ossification GO:0045778 47 20 0,000 0,0816805 0,11560193 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,0816805 0,11553397 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,0816805 0,11546609 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,0816805 0,11539829 ! cAMP metabolic process GO:0046058 36 20 0,000 0,0816805 0,11533057 ! response to vitamin GO:0033273 31 20 0,000 0,0816805 0,11526292 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,0816805 0,11519536 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,0816805 0,11512788 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,0816805 0,11506047 ! response to alkaloid GO:0043279 38 20 0,000 0,0816805 0,11499315 ! retinoid metabolic process GO:0001523 32 20 0,000 0,0816805 0,1149259 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,0816805 0,11485873 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,0816805 0,11479164 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,0816805 0,11472463 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,0816805 0,11465769 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,0816805 0,11459084 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,0816805 0,11452406 ! body fluid secretion GO:0007589 31 20 0,000 0,0816805 0,11445736 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,0816805 0,11439074 ! peptide secretion GO:0002790 35 20 0,000 0,0816805 0,11432419 ! stem cell differentiation GO:0048863 53 20 0,000 0,0816805 0,11425772 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,0816805 0,11419133 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,0816805 0,11412502 ! sensory perception of pain GO:0019233 30 20 0,000 0,0816805 0,11405878 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,0816805 0,11399263 ! diencephalon development GO:0021536 34 20 0,000 0,0816805 0,11392654 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,0816805 0,11386054 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,0816805 0,11379461 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,0816805 0,11372875 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,0816805 0,11366298 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,0816805 0,11359728 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,0816805 0,11353165 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,0816805 0,1134661 ! regulation of glucose import GO:0046324 29 20 0,000 0,0816805 0,11340063 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,0816805 0,11333523 ! actin filament-based movement GO:0030048 43 20 0,000 0,0816805 0,11326991 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,0816805 0,11320466 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,0816805 0,11313949 ! negative regulation of translation GO:0017148 29 20 0,000 0,0816805 0,11307439 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,0816805 0,11300937 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,0816805 0,11294442 ! regulation of cell killing GO:0031341 42 21 0,000 0,08558604 0,11827685 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,08558604 0,11820896 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,08558604 0,11814114 ! hormone secretion GO:0046879 38 21 0,000 0,08558604 0,1180734 ! glycerol metabolic process GO:0006071 34 21 0,000 0,08558604 0,11800573 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,08558604 0,11793815 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,08558604 0,11787064 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,08558604 0,11780321 ! axis specification GO:0009798 38 21 0,000 0,08558604 0,11773585 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,08558604 0,11766857 ! smooth muscle contraction GO:0006939 46 21 0,000 0,08558604 0,11760137 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,08558604 0,11753425 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,08558604 0,1174672 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,08558604 0,11740023 ! cell aging GO:0007569 44 21 0,000 0,08558604 0,11733334 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,08558604 0,11726652 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,08558604 0,11719977 ! cytolysis GO:0019835 24 21 0,000 0,08558604 0,11713311 ! vasodilation GO:0042311 39 21 0,000 0,08558604 0,11706652 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,08558604 0,117 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,08558604 0,11693356 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,08558604 0,1168672 ! oogenesis GO:0048477 36 21 0,000 0,08558604 0,11680091 ! DNA modification GO:0006304 34 21 0,000 0,08558604 0,1167347 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,08558604 0,11666856 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,08558604 0,11660249 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,08558604 0,1165365 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,08558604 0,11647059 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,08558604 0,11640475 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,08558604 0,11633899 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,08558604 0,11627329 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,08558604 0,11620768 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,08558604 0,11614213 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,08558604 0,11607667 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,08558604 0,11601127 ! collagen catabolic process GO:0030574 28 21 0,000 0,08558604 0,11594595 ! sperm-egg recognition GO:0035036 21 21 0,000 0,08558604 0,1158807 ! gut development GO:0048565 39 21 0,000 0,08558604 0,11581553 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,08947509 0,12101016 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,08947509 0,12094217 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,08947509 0,12087427 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,08947509 0,12080644 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,08947509 0,12073868 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,08947509 0,120671 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,08947509 0,1206034 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,08947509 0,12053587 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,08947509 0,12046842 ! regeneration GO:0031099 41 22 0,000 0,08947509 0,12040105 ! keratinization GO:0031424 28 22 0,000 0,08947509 0,12033374 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,08947509 0,12026652 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,08947509 0,12019937 ! sensory perception of taste GO:0050909 28 22 0,000 0,08947509 0,12013229 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,08947509 0,12006529 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,08947509 0,11999837 ! vacuolar transport GO:0007034 36 22 0,000 0,08947509 0,11993152 ! lysosome organization GO:0007040 41 22 0,000 0,08947509 0,11986474 ! central nervous system neuron development GO:0021954 46 22 0,000 0,08947509 0,11979804 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,08947509 0,11973141 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,08947509 0,11966485 ! fucose metabolic process GO:0006004 39 22 0,000 0,08947509 0,11959837 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,08947509 0,11953197 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,08947509 0,11946563 ! ureteric bud development GO:0001657 43 22 0,000 0,08947509 0,11939937 ! renal system process GO:0003014 41 22 0,000 0,08947509 0,11933319 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,08947509 0,11926707 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,08947509 0,11920104 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,08947509 0,11913507 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,08947509 0,11906918 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,08947509 0,11900336 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,08947509 0,11893761 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,08947509 0,11887193 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,09334773 0,12394848 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,09334773 0,12388011 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,09334773 0,12381182 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,09334773 0,12374361 ! gluconeogenesis GO:0006094 33 23 0,000 0,09334773 0,12367547 ! viral genome replication GO:0019079 41 23 0,000 0,09334773 0,1236074 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,09334773 0,12353941 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,09334773 0,12347149 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,09334773 0,12340365 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,09334773 0,12333589 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,09334773 0,12326819 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,09334773 0,12320058 ! visual behavior GO:0007632 42 23 0,000 0,09334773 0,12313303 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,09334773 0,12306556 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,09334773 0,12299816 ! response to ethanol GO:0045471 46 23 0,000 0,09334773 0,12293084 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,09334773 0,12286359 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,09334773 0,12279642 ! peroxisome organization GO:0007031 37 23 0,000 0,09334773 0,12272932 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,09334773 0,12266229 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,09334773 0,12259533 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,09334773 0,12252845 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,09334773 0,12246164 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,09334773 0,1223949 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,09334773 0,12232824 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,09334773 0,12226165 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,09334773 0,12219513 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,09334773 0,12212868 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,09334773 0,12206231 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,09334773 0,12199601 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,09334773 0,12192978 ! fatty acid transport GO:0015908 44 23 0,000 0,09334773 0,12186362 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,09334773 0,12179753 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,09334773 0,12173152 ! hormone transport GO:0009914 40 23 0,000 0,09334773 0,12166557 ! cell-cell recognition GO:0009988 25 23 0,000 0,09334773 0,1215997 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,09334773 0,1215339 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,09334773 0,12146817 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,09334773 0,12140251 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,09334773 0,12133693 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,09334773 0,12127141 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,09720403 0,12621312 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,09720403 0,12614504 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,09720403 0,12607704 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,09720403 0,12600911 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,09720403 0,12594125 ! vesicle docking GO:0048278 47 24 0,000 0,09720403 0,12587347 ! spinal cord development GO:0021510 47 24 0,000 0,09720403 0,12580576 ! vacuole organization GO:0007033 43 24 0,000 0,09720403 0,12573812 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,09720403 0,12567056 ! digestive system process GO:0022600 39 24 0,000 0,09720403 0,12560306 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,09720403 0,12553564 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,09720403 0,1254683 ! regulation of behavior GO:0050795 43 24 0,000 0,09720403 0,12540102 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,09720403 0,12533382 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,09720403 0,12526669 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,09720403 0,12519963 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,09720403 0,12513264 ! membrane depolarization GO:0051899 39 24 0,000 0,09720403 0,12506573 ! pentose metabolic process GO:0019321 35 24 0,000 0,09720403 0,12499888 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,09720403 0,12493211 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,09720403 0,12486541 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,09720403 0,12479878 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,09720403 0,12473222 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,09720403 0,12466573 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,09720403 0,12459931 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,09720403 0,12453296 ! regulation of amine transport GO:0051952 40 24 0,000 0,09720403 0,12446669 ! protein tetramerization GO:0051262 52 24 0,000 0,09720403 0,12440048 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,10104406 0,12924615 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,10104406 0,12917747 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,10104406 0,12910887 ! phototransduction GO:0007602 33 25 0,000 0,10104406 0,12904034 ! vasculogenesis GO:0001570 46 25 0,000 0,10104406 0,12897189 ! sperm motility GO:0030317 31 25 0,000 0,10104406 0,1289035 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,10104406 0,12883519 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,10104406 0,12876695 ! receptor metabolic process GO:0043112 46 25 0,000 0,10104406 0,12869879 ! chromosome condensation GO:0030261 45 25 0,000 0,10104406 0,12863069 ! osteoblast differentiation GO:0001649 60 25 0,000 0,10104406 0,12856267 ! neural crest cell development GO:0014032 54 25 0,000 0,10104406 0,12849472 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,10104406 0,12842684 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,10104406 0,12835903 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,10104406 0,1282913 ! interaction with host GO:0051701 62 25 0,000 0,10104406 0,12822363 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,10104406 0,12815604 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,10104406 0,12808852 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,10104406 0,12802107 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,10104406 0,12795369 ! immunoglobulin production GO:0002377 55 25 0,000 0,10104406 0,12788638 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,10104406 0,12781914 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,10104406 0,12775197 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,10104406 0,12768488 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,10104406 0,12761785 ! telomere organization GO:0032200 43 25 0,000 0,10104406 0,1275509 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,10104406 0,12748401 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,10104406 0,12741719 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,10486788 0,13216978 ! embryonic pattern specification GO:0009880 44 26 0,000 0,10486788 0,13210058 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,10486788 0,13203146 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,10486788 0,1319624 ! initiation of viral infection GO:0019059 57 26 0,000 0,10486788 0,13189342 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,10486788 0,13182451 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,10486788 0,13175567 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,10486788 0,13168691 ! molting cycle process GO:0022404 50 26 0,000 0,10486788 0,13161821 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,10486788 0,13154959 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,10486788 0,13148104 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,10486788 0,13141256 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,10486788 0,13134415 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,10486788 0,13127581 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,10486788 0,13120755 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,10486788 0,13113935 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,10486788 0,13107123 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,10486788 0,13100318 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,10486788 0,13093519 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,10486788 0,13086728 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,10486788 0,13079944 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,10486788 0,13073167 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,10486788 0,13066396 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,10486788 0,13059633 ! leukocyte proliferation GO:0070661 52 26 0,000 0,10486788 0,13052877 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,10486788 0,13046128 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,10486788 0,13039386 ! neuron fate commitment GO:0048663 48 27 0,000 0,10867556 0,13505857 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,10867556 0,13498885 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,10867556 0,13491919 ! iron ion transport GO:0006826 59 27 0,000 0,10867556 0,13484961 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,10867556 0,1347801 ! protein amino acid acylation GO:0043543 55 27 0,000 0,10867556 0,13471066 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,10867556 0,13464129 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,10867556 0,134572 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,10867556 0,13450278 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,10867556 0,13443362 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,10867556 0,13436454 ! autophagy GO:0006914 41 27 0,000 0,10867556 0,13429553 ! male gonad development GO:0008584 44 27 0,000 0,10867556 0,13422659 ! response to toxin GO:0009636 47 27 0,000 0,10867556 0,13415772 ! primary neural tube formation GO:0014020 51 27 0,000 0,10867556 0,13408892 ! base-excision repair GO:0006284 41 27 0,000 0,10867556 0,13402019 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,10867556 0,13395153 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,10867556 0,13388295 ! glutathione metabolic process GO:0006749 39 27 0,000 0,10867556 0,13381443 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,10867556 0,13374598 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,10867556 0,1336776 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,11246717 0,13827083 ! circadian rhythm GO:0007623 50 28 0,000 0,11246717 0,13820021 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,11246717 0,13812966 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,11246717 0,13805919 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,11246717 0,13798878 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,11246717 0,13791845 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,11246717 0,1378482 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,11246717 0,13777801 ! synaptogenesis GO:0007416 42 28 0,000 0,11246717 0,13770789 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,11246717 0,13763785 ! lipid oxidation GO:0034440 43 28 0,000 0,11246717 0,13756787 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,11246717 0,13749797 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,11246717 0,13742814 ! translational initiation GO:0006413 65 29 0,000 0,11624277 0,1419696 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,11624277 0,14189757 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,11624277 0,14182562 ! regulation of pH GO:0006885 43 29 0,000 0,11624277 0,14175373 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,11624277 0,14168192 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,11624277 0,14161018 ! catechol metabolic process GO:0009712 54 29 0,000 0,11624277 0,14153852 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,11624277 0,14146693 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,11624277 0,14139541 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,11624277 0,14132396 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,11624277 0,14125258 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,11624277 0,14118128 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,11624277 0,14111005 ! cell fate determination GO:0001709 60 29 0,000 0,11624277 0,14103889 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,11624277 0,1409678 ! detection of light stimulus GO:0009583 38 29 0,000 0,11624277 0,14089678 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,11624277 0,14082584 ! tissue homeostasis GO:0001894 48 29 0,000 0,11624277 0,14075496 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,11624277 0,14068416 ! phenol metabolic process GO:0018958 55 30 0,000 0,12000244 0,14516133 ! zinc ion transport GO:0006829 45 30 0,000 0,12000244 0,14508838 ! membrane docking GO:0022406 61 30 0,000 0,12000244 0,14501551 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,12000244 0,14494271 ! regulation of innate immune response GO:0045088 51 30 0,000 0,12000244 0,14486998 ! acute-phase response GO:0006953 49 30 0,000 0,12000244 0,14479733 ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,12000244 0,14472475 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,12000244 0,14465224 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,12000244 0,14457981 ! phospholipid transport GO:0015914 51 30 0,000 0,12000244 0,14450745 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,12000244 0,14443516 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,12000244 0,14436294 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,12000244 0,14429079 ! eye morphogenesis GO:0048592 60 30 0,000 0,12000244 0,14421872 ! response to heat GO:0009408 50 30 0,000 0,12000244 0,14414672 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,12374624 0,14856959 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,12374624 0,14849549 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,12374624 0,14842147 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,12374624 0,14834751 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,12374624 0,14827364 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,12374624 0,14819983 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,12374624 0,1481261 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,12374624 0,14805244 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,12374624 0,14797886 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,12374624 0,14790534 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,12374624 0,14783191 ! peptide transport GO:0015833 55 31 0,000 0,12374624 0,14775854 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,12374624 0,14768525 ! iron ion homeostasis GO:0055072 54 31 0,000 0,12374624 0,14761203 ! mesoderm formation GO:0001707 69 31 0,000 0,12374624 0,14753888 ! natural killer cell activation GO:0030101 45 31 0,000 0,12374624 0,1474658 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,12374624 0,1473928 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,12374624 0,14731987 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,12374624 0,14724701 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,12374624 0,14717423 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,12374624 0,14710151 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,12747424 0,15145828 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,12747424 0,15138352 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,12747424 0,15130884 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,12747424 0,15123423 ! cholesterol transport GO:0030301 56 32 0,000 0,12747424 0,15115969 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,12747424 0,15108523 ! spindle organization GO:0007051 46 32 0,000 0,12747424 0,15101084 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,12747424 0,15093652 ! metanephros development GO:0001656 74 32 0,000 0,12747424 0,15086228 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,12747424 0,15078811 ! response to ionizing radiation GO:0010212 65 32 0,000 0,12747424 0,15071401 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,12747424 0,15063999 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,12747424 0,15056604 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,12747424 0,15049216 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,12747424 0,15041835 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,12747424 0,15034462 ! BMP signaling pathway GO:0030509 64 32 0,000 0,12747424 0,15027095 ! hindbrain development GO:0030902 61 32 0,000 0,12747424 0,15019736 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,12747424 0,15012385 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,12747424 0,1500504 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,12747424 0,14997703 ! gene silencing GO:0016458 65 32 0,000 0,12747424 0,14990372 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,1311865 0,1541938 ! post-embryonic development GO:0009791 69 33 0,000 0,1311865 0,15411851 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,1311865 0,15404329 ! protein targeting to membrane GO:0006612 68 33 0,000 0,1311865 0,15396815 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,1311865 0,15389308 ! ceramide metabolic process GO:0006672 64 33 0,000 0,1311865 0,15381809 ! formation of primary germ layer GO:0001704 72 33 0,000 0,1311865 0,15374316 ! cell fate specification GO:0001708 52 33 0,000 0,1311865 0,15366831 ! sterol transport GO:0015918 57 33 0,000 0,1311865 0,15359353 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,1311865 0,15351883 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,1311865 0,1534442 ! adult locomotory behavior GO:0008344 59 33 0,000 0,1311865 0,15336964 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,1311865 0,15329515 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,1311865 0,15322073 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,13488308 0,15746177 ! glial cell differentiation GO:0010001 63 34 0,000 0,13488308 0,1573854 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,13488308 0,15730911 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,13488308 0,1572329 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,13488308 0,15715676 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,13488308 0,15708069 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,13488308 0,15700469 ! mismatch repair GO:0006298 46 34 0,000 0,13488308 0,15692877 ! spermatid development GO:0007286 63 34 0,000 0,13488308 0,15685292 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,13488308 0,15677715 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,13488308 0,15670145 ! placenta development GO:0001890 53 34 0,000 0,13488308 0,15662582 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,13488308 0,15655027 ! regulation of muscle development GO:0048634 70 35 0,000 0,13856407 0,16074501 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,13856407 0,16066754 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,13856407 0,16059015 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,13856407 0,16051283 ! odontogenesis GO:0042476 66 35 0,000 0,13856407 0,16043558 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,13856407 0,16035841 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,13856407 0,16028132 GO:0006639|acylglycerol metabolic process, ! cytokine production GO:0001816 59 35 0,000 0,13856407 0,1602043 ! neural tube formation GO:0001841 67 35 0,000 0,13856407 0,16012735 ! vesicle localization GO:0051648 64 35 0,000 0,13856407 0,16005048 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,14222951 0,16420547 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,14222951 0,16412671 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,14222951 0,16404803 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,14222951 0,16396943 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,14222951 0,1638909 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,14222951 0,16381244 ! positive regulation of cell development GO:0010720 80 36 0,000 0,14222951 0,16373406 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,14222951 0,16365576 ! regulation of proteolysis GO:0030162 72 36 0,000 0,14222951 0,16357753 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,14222951 0,16349938 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,14222951 0,1634213 ! aerobic respiration GO:0009060 55 36 0,000 0,14222951 0,16334329 ! embryonic organ development GO:0048568 57 36 0,000 0,14222951 0,16326536 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,14222951 0,1631875 ! RNA export from nucleus GO:0006405 56 37 0,000 0,14587947 0,16729552 ! meiosis I GO:0007127 65 37 0,000 0,14587947 0,16721582 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,14587947 0,1671362 ! sister chromatid segregation GO:0000819 58 37 0,000 0,14587947 0,16705664 ! organic anion transport GO:0015711 68 37 0,000 0,14587947 0,16697717 ! tissue remodeling GO:0048771 76 37 0,000 0,14587947 0,16689777 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,14587947 0,16681845 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,14587947 0,1667392 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,14587947 0,16666002 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,14587947 0,16658093 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,14587947 0,1665019 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,14587947 0,16642295 ! spermatid differentiation GO:0048515 66 37 0,000 0,14587947 0,16634408 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,14951403 0,17040775 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,14951403 0,17032706 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,14951403 0,17024645 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,14951403 0,17016592 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,14951403 0,17008546 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,14951403 0,17000508 ! nucleus organization GO:0006997 67 38 0,000 0,14951403 0,16992478 ! lipid homeostasis GO:0055088 67 38 0,000 0,14951403 0,16984455 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,14951403 0,16976439 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,14951403 0,16968432 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,14951403 0,16960431 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,14951403 0,16952439 ! learning GO:0007612 77 39 0,000 0,15313324 0,17354619 ! ear morphogenesis GO:0042471 60 39 0,000 0,15313324 0,17346449 ! organic ether metabolic process GO:0018904 55 39 0,000 0,15313324 0,17338286 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,15313324 0,1733013 ! segmentation GO:0035282 67 39 0,000 0,15313324 0,17321983 ! ion transmembrane transport GO:0034220 66 39 0,000 0,15313324 0,17313843 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,15313324 0,1730571 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,15313324 0,17297585 ! RNA modification GO:0009451 57 39 0,000 0,15313324 0,17289468 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,15313324 0,17281359 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,15673717 0,17679776 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,15673717 0,17671491 ! feeding behavior GO:0007631 59 40 0,000 0,15673717 0,17663214 ! negative regulation of binding GO:0051100 72 40 0,000 0,15673717 0,17654945 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,15673717 0,17646683 ! mesenchymal cell development GO:0014031 87 40 0,000 0,15673717 0,17638429 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,15673717 0,17630183 ! maintenance of protein location GO:0045185 91 40 0,000 0,15673717 0,17621945 ! cytokinesis GO:0000910 72 40 0,000 0,15673717 0,17613714 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,16032588 0,18008593 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,16032588 0,18000189 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,16032588 0,17991794 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,16032588 0,17983406 ! gliogenesis GO:0042063 88 41 0,000 0,16032588 0,17975026 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,16032588 0,17966654 ! T cell differentiation GO:0030217 81 41 0,000 0,16032588 0,17958289 ! female gamete generation GO:0007292 61 41 0,000 0,16032588 0,17949933 ! polyol metabolic process GO:0019751 66 41 0,000 0,16032588 0,17941584 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,16032588 0,17933243 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,16389943 0,18324444 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,16389943 0,18315933 ! regulation of tube size GO:0035150 71 42 0,000 0,16389943 0,1830743 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,16389943 0,18298934 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,16389943 0,18290447 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,16389943 0,18281967 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,16389943 0,18273496 ! neuron migration GO:0001764 79 42 0,000 0,16389943 0,18265032 ! regulation of protein secretion GO:0050708 71 42 0,000 0,16389943 0,18256576 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,1674579 0,18644318 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,1674579 0,18635694 ! glucose transport GO:0015758 65 43 0,000 0,1674579 0,18627078 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,1674579 0,18618471 ! neural tube development GO:0021915 77 43 0,000 0,1674579 0,18609871 ! phagocytosis GO:0006909 90 43 0,000 0,1674579 0,18601279 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,1674579 0,18592695 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,17100134 0,18977362 ! hexose transport GO:0008645 67 44 0,000 0,17100134 0,18968613 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 0,000 0,17100134 0,18959872 ! double-strand break repair GO:0006302 81 44 0,000 0,17100134 0,18951139 ! B cell differentiation GO:0030183 107 44 0,000 0,17100134 0,18942413 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,17100134 0,18933696 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,17100134 0,18924987 ! developmental growth GO:0048589 82 44 0,000 0,17100134 0,18916286 ! maintenance of location in cell GO:0051651 97 44 0,000 0,17100134 0,18907593 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,17452981 0,19288871 ! glycolysis GO:0006096 65 45 0,000 0,17452981 0,19280015 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,17452981 0,19271167 ! leukocyte migration GO:0050900 68 45 0,000 0,17452981 0,19262327 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,17452981 0,19253495 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,17452981 0,19244671 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,17452981 0,19235856 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,17452981 0,19227048 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,17452981 0,19218248 ! cell growth GO:0016049 84 45 0,000 0,17452981 0,19209457 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,17804339 0,19587215 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,17804339 0,19578263 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,17804339 0,19569319 ! pigmentation GO:0043473 100 46 0,000 0,17804339 0,19560383 ! positive regulation of defense response GO:0031349 76 47 0,000 0,18154212 0,19935661 ! response to calcium ion GO:0051592 81 47 0,000 0,18154212 0,19926567 ! endosome transport GO:0016197 108 47 0,000 0,18154212 0,1991748 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,18154212 0,19908402 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,18154212 0,19899332 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,18154212 0,19890271 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,18154212 0,19881217 ! protein homooligomerization GO:0051260 76 47 0,000 0,18154212 0,19872172 ! mitochondrial transport GO:0006839 82 48 0,000 0,18502608 0,20244327 ! cellular component disassembly GO:0022411 86 48 0,000 0,18502608 0,20235125 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,18502608 0,20225931 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,18502608 0,20216746 ! activation of caspase activity GO:0006919 84 48 0,000 0,18502608 0,20207569 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,18502608 0,201984 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,18502608 0,2018924 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,18849532 0,20558465 ! regulation of ion transport GO:0043269 77 49 0,000 0,18849532 0,2054915 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,18849532 0,20539843 ! peptide metabolic process GO:0006518 76 49 0,000 0,18849532 0,20530545 ! response to temperature stimulus GO:0009266 76 49 0,000 0,18849532 0,20521255 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,18849532 0,20511974 ! endocrine system development GO:0035270 104 49 0,000 0,18849532 0,20502701 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,18849532 0,20493436 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,18849532 0,2048418 GO:0019724|B cell mediated immunity, ! regulation of cell projection organization GO:0031344 121 50 0,000 0,19194991 0,2085018 ! neuromuscular process GO:0050905 99 50 0,000 0,19194991 0,20840771 ! regulation of ossification GO:0030278 117 50 0,000 0,19194991 0,20831371 ! inner ear development GO:0048839 79 50 0,000 0,19194991 0,20821979 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,19194991 0,20812595 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,19194991 0,2080322 ! positive regulation of binding GO:0051099 78 51 0,000 0,19538991 0,21166507 ! viral infectious cycle GO:0019058 99 51 0,000 0,19538991 0,21156981 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,19538991 0,21147464 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,19538991 0,21137955 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,19538991 0,21128455 ! excretion GO:0007588 83 51 0,000 0,19538991 0,21118963 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,19538991 0,2110948 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,19538991 0,21100005 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,19538991 0,21090539 ! vesicle organization GO:0016050 107 51 0,000 0,19538991 0,21081082 ! regulation of cell shape GO:0008360 125 51 0,000 0,19538991 0,21071632 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,19538991 0,21062192 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,19881538 0,21421845 ! membrane fusion GO:0006944 110 52 0,000 0,19881538 0,21412256 ! amino acid activation GO:0043038 92 52 0,000 0,19881538 0,21402675 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,19881538 0,21393103 ! regulation of translational initiation GO:0006446 82 53 0,000 0,20222637 0,21750409 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,20222637 0,2174069 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,20222637 0,2173098 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,20222637 0,21721279 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,20222637 0,21711586 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,20222637 0,21701902 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,20562296 0,22056569 ! cell recognition GO:0008037 85 54 0,000 0,20562296 0,2204674 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,20562296 0,2203692 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,20562296 0,22027108 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,20562296 0,22017305 ! chloride transport GO:0006821 90 55 0,000 0,2090052 0,22369507 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,2090052 0,2235956 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,2090052 0,22349623 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,2090052 0,22339694 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,2090052 0,22329774 ! aging GO:0007568 103 55 0,000 0,2090052 0,22319863 ! gastrulation GO:0007369 112 55 0,000 0,2090052 0,22309961 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,2090052 0,22300067 ! RNA elongation GO:0006354 79 55 0,000 0,2090052 0,22290182 ! nuclear export GO:0051168 97 55 0,000 0,2090052 0,22280306 ! regulation of actin filament length GO:0030832 105 56 0,000 0,21237315 0,22629309 ! sensory perception of smell GO:0007608 80 56 0,000 0,21237315 0,22619292 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,21237315 0,22609283 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,21237315 0,22599284 ! regulation of DNA replication GO:0006275 101 56 0,000 0,21237315 0,22589293 ! proton transport GO:0015992 94 56 0,000 0,21237315 0,22579311 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,21572687 0,22925745 ! maintenance of location GO:0051235 118 57 0,000 0,21572687 0,22915623 ! hydrogen transport GO:0006818 97 58 0,000 0,21906643 0,23260098 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,21906643 0,23249838 ! adult behavior GO:0030534 99 58 0,000 0,21906643 0,23239586 ! regulation of cellular component size GO:0032535 109 59 0,000 0,22239187 0,23581967 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,22239187 0,23571579 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,22239187 0,23561199 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,22239187 0,23550829 ! DNA catabolic process GO:0006308 86 59 0,000 0,22239187 0,23540468 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,22239187 0,23530116 ! establishment of organelle localization GO:0051656 109 59 0,000 0,22239187 0,23519773 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,22570326 0,23859492 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,22570326 0,23849014 ! regulation of heart contraction GO:0008016 110 60 0,000 0,22570326 0,23838545 ! camera-type eye development GO:0043010 116 60 0,000 0,22570326 0,23828085 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,22570326 0,23817634 ! kidney development GO:0001822 122 60 0,000 0,22570326 0,23807192 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,22900066 0,24144417 ! mesoderm development GO:0007498 119 61 0,000 0,22900066 0,24133841 ! tRNA processing GO:0008033 89 61 0,000 0,22900066 0,24123275 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,22900066 0,24112717 ! ear development GO:0043583 103 62 0,000 0,23228413 0,24447752 ! viral reproductive process GO:0022415 126 62 0,000 0,23228413 0,24437062 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,23228413 0,24426382 ! regulation of mitosis GO:0007088 105 63 0,000 0,23555372 0,24759382 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,23555372 0,2474857 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,23555372 0,24737768 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,2388095 0,25068746 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,2388095 0,25057813 ! single fertilization GO:0007338 75 64 0,000 0,2388095 0,2504689 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,24205152 0,25375859 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,24205152 0,25364806 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,24205152 0,25353764 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,24527984 0,25680735 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,24527984 0,25669565 ! extracellular matrix organization GO:0030198 133 66 0,000 0,24527984 0,25658404 ! secondary metabolic process GO:0019748 116 66 0,000 0,24527984 0,25647253 ! cell projection assembly GO:0030031 120 66 0,000 0,24527984 0,25636112 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,24849451 0,25960825 ! activation of MAPK activity GO:0000187 115 67 0,000 0,24849451 0,25949557 ! hexose catabolic process GO:0019320 104 67 0,000 0,24849451 0,25938299 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,24849451 0,25927051 ! adaptive immune response GO:0002250 119 67 0,000 0,24849451 0,25915813 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,24849451 0,25904584 ! amino acid transport GO:0006865 125 68 0,000 0,2516956 0,26226921 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,2516956 0,26215568 ! viral reproduction GO:0016032 134 68 0,000 0,2516956 0,26204224 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,25488316 0,26524606 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,25488316 0,26513138 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,25488316 0,2650168 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,25488316 0,26490232 ! antigen processing and presentation GO:0019882 104 69 0,000 0,25488316 0,26478795 ! appendage morphogenesis GO:0035107 135 70 0,000 0,25805725 0,26796967 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,26121792 0,27113473 ! appendage development GO:0048736 136 71 0,000 0,26121792 0,27101781 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,26121792 0,27090099 ! B cell activation GO:0042113 160 71 0,000 0,26121792 0,27078428 ! regulation of immune effector process GO:0002697 137 71 0,000 0,26121792 0,27066766 ! acute inflammatory response GO:0002526 113 72 0,000 0,26436523 0,27381091 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,26436523 0,27369309 ! carbohydrate transport GO:0008643 110 72 0,000 0,26436523 0,27357537 ! learning or memory GO:0007611 147 73 0,000 0,26749924 0,27669955 ! regulation of blood pressure GO:0008217 125 73 0,000 0,26749924 0,27658064 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,26749924 0,27646184 ! fertilization GO:0009566 90 73 0,000 0,26749924 0,27634313 ! regulation of transcription factor activity GO:0051090 126 74 0,000 0,27061999 0,27944708 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 126 74 0,000 0,27061999 0,2793272 ! neurotransmitter transport GO:0006836 123 74 0,000 0,27061999 0,27920742 ! meiosis GO:0007126 121 74 0,000 0,27061999 0,27908774 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,27061999 0,27896817 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,27061999 0,2788487 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,27061999 0,27872933 ! eye development GO:0001654 143 74 0,000 0,27061999 0,27861006 ! organelle localization GO:0051640 136 74 0,000 0,27061999 0,27849089 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,27372756 0,28156841 ! meiotic cell cycle GO:0051321 122 75 0,000 0,27372756 0,28144808 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,27372756 0,28132786 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,27682199 0,28438673 ! defense response to bacterium GO:0042742 89 76 0,000 0,27682199 0,28426535 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,27682199 0,28414408 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,27682199 0,28402291 ! regulation of catabolic process GO:0009894 161 76 0,000 0,27682199 0,28390184 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,27990334 0,28693968 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,27990334 0,28681748 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,28297166 0,28983815 ! protein oligomerization GO:0051259 139 78 0,000 0,28297166 0,28971482 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,28602701 0,29271841 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,28906944 0,29570624 ! response to metal ion GO:0010038 140 80 0,000 0,28906944 0,29558057 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,28906944 0,295455 ! protein import into nucleus GO:0006606 158 80 0,000 0,28906944 0,29532954 ! inorganic anion transport GO:0015698 138 80 0,000 0,28906944 0,29520419 ! T cell activation GO:0042110 168 81 0,000 0,29209901 0,2981715 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,29209901 0,29804504 ! nuclear import GO:0051170 161 81 0,000 0,29209901 0,2979187 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,29511577 0,30086802 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,29511577 0,30074059 ! response to drug GO:0042493 143 82 0,000 0,29511577 0,30061327 ! response to nutrient GO:0007584 125 82 0,000 0,29511577 0,30048605 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,29511577 0,30035894 ! regulation of lyase activity GO:0051339 160 83 0,000 0,29811977 0,30328802 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,30111107 0,3062017 ! response to unfolded protein GO:0006986 131 85 0,000 0,30408972 0,30910007 ! nucleosome assembly GO:0006334 122 85 0,000 0,30408972 0,30896953 ! amine biosynthetic process GO:0009309 138 86 0,000 0,30705577 0,31185149 ! response to inorganic substance GO:0010035 153 86 0,000 0,30705577 0,31171991 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,30705577 0,31158844 ! chromatin assembly GO:0031497 124 86 0,000 0,30705577 0,31145707 ! alcohol catabolic process GO:0046164 130 86 0,000 0,30705577 0,31132582 ! amine transport GO:0015837 155 86 0,000 0,30705577 0,31119468 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,31000928 0,31405572 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,31000928 0,31392354 ! protein localization in nucleus GO:0034504 176 87 0,000 0,31000928 0,31379147 ! regulation of DNA binding GO:0051101 155 88 0,000 0,3129503 0,31663516 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,3129503 0,31650207 ! cellular defense response GO:0006968 114 89 0,000 0,31587888 0,31932966 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,31587888 0,31919554 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,31879508 0,32200712 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,31879508 0,32187199 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,31879508 0,32173698 ! sterol metabolic process GO:0016125 152 91 0,000 0,32169894 0,32453151 ! response to protein stimulus GO:0051789 149 91 0,000 0,32169894 0,32439549 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,32169894 0,32425959 ! regulation of defense response GO:0031347 149 92 0,000 0,32459051 0,32703718 ! nucleosome organization GO:0034728 138 92 0,000 0,32459051 0,32690028 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,32459051 0,32676351 ! vitamin metabolic process GO:0006766 139 92 0,000 0,32459051 0,32662684 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,32746986 0,32938649 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,32746986 0,32924885 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,32746986 0,32911132 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,33033703 0,33185424 ! female pregnancy GO:0007565 164 94 0,000 0,33033703 0,33171573 ! leukocyte differentiation GO:0002521 202 96 0,000 0,33603503 0,33729674 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,33603503 0,33715608 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,33603503 0,33701554 ! positive regulation of immune response GO:0050778 156 96 0,000 0,33603503 0,33687512 ! regulation of DNA metabolic process GO:0051052 178 97 0,000 0,33886597 0,33957164 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,33886597 0,33943027 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,34168493 0,3421115 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,34168493 0,34196919 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,34449196 0,3446352 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,34449196 0,34449196