pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6536-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! G1/S transition of mitotic cell cycle GO:0000082 124 46 5,000 3,263E-08 7,972E-05 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 3,000 3,406E-07 4,161E-04 ! negative regulation of protein kinase activity GO:0006469 144 69 5,000 3,869E-07 3,151E-04 ! negative regulation of kinase activity GO:0033673 145 70 5,000 4,218E-07 2,576E-04 ! negative regulation of transferase activity GO:0051348 155 74 5,000 5,88E-07 2,873E-04 ! negative regulation of hormone secretion GO:0046888 26 17 3,000 5,902E-07 2,403E-04 ! hemoglobin biosynthetic process GO:0042541 8 5 2,000 6,473E-07 2,259E-04 ! cellular glucose homeostasis GO:0001678 6 5 2,000 6,473E-07 1,977E-04 ! negative regulation of macrophage differentiation GO:0045650 7 5 2,000 6,473E-07 1,757E-04 ! positive regulation of hormone secretion GO:0046887 35 19 3,000 9,551E-07 2,333E-04 ! activation of MAPKKK activity GO:0000185 12 6 2,000 1,291E-06 2,867E-04 ! negative regulation of B cell activation GO:0050869 14 6 2,000 1,291E-06 2,628E-04 ! ovarian follicle development GO:0001541 39 21 3,000 1,466E-06 2,754E-04 ! negative regulation of phosphorylation GO:0042326 52 24 3,000 2,577E-06 4,498E-04 ! interphase of mitotic cell cycle GO:0051329 224 98 5,000 3,085E-06 5,025E-04 ! hemoglobin metabolic process GO:0020027 14 8 2,000 3,593E-06 5,486E-04 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 3,593E-06 5,163E-04 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 3,000 3,604E-06 4,891E-04 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of lymphocyte activation GO:0051250 55 27 3,000 4,217E-06 5,422E-04 ! regulation of macrophage differentiation GO:0045649 16 9 2,000 5,373E-06 6,564E-04 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 2,000 5,373E-06 6,251E-04 ! regulation of B cell activation GO:0050864 55 30 3,000 6,523E-06 7,244E-04 ! ovulation cycle process GO:0022602 55 31 3,000 7,466E-06 7,93E-04 ! negative regulation of leukocyte activation GO:0002695 60 31 3,000 7,466E-06 7,6E-04 ! motor axon guidance GO:0008045 22 10 2,000 7,653E-06 7,479E-04 ! regulation of B cell differentiation GO:0045577 24 10 2,000 7,653E-06 7,191E-04 ! ovulation cycle GO:0042698 57 32 3,000 8,506E-06 7,696E-04 ! negative regulation of secretion GO:0051048 68 35 3,000 1,227E-05 1,07E-03 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 2,000 1,395E-05 1,175E-03 ! reproductive structure development GO:0048608 131 75 4,000 1,398E-05 1,139E-03 ! female gonad development GO:0008585 71 37 3,000 1,538E-05 1,212E-03 ! negative regulation of cell activation GO:0050866 69 37 3,000 1,538E-05 1,174E-03 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 2,000 1,808E-05 1,338E-03 ! carbohydrate homeostasis GO:0033500 59 39 3,000 1,903E-05 1,367E-03 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 80 40 3,000 2,108E-05 1,471E-03 GO:0046660|female sex differentiation, ! regulation of hormone secretion GO:0046883 69 41 3,000 2,328E-05 1,58E-03 ! activation of MAPKK activity GO:0000186 43 17 2,000 4,248E-05 2,805E-03 ! regulation of lymphocyte differentiation GO:0045619 92 49 3,000 4,751E-05 3,054E-03 ! negative regulation of immune system process GO:0002683 101 51 3,000 5,568E-05 3,488E-03 ! actin filament bundle formation GO:0051017 47 20 2,000 7,058E-05 4,31E-03 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 2,000 7,058E-05 4,205E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 8,637E-05 5,024E-03 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 2,000 9,478E-05 5,385E-03 ! positive regulation of secretion GO:0051047 110 61 3,000 1,127E-04 6,257E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 1,238E-04 6,722E-03 ! multicellular organism reproduction GO:0032504 123 65 3,000 1,444E-04 7,667E-03 GO:0048609|reproductive process in a multicellular organism, ! regulation of cytokine biosynthetic process GO:0042035 108 66 3,000 1,532E-04 7,964E-03 ! gonad development GO:0008406 115 66 3,000 1,532E-04 7,798E-03 ! positive regulation of histone modification GO:0031058 6 5 1,000 1,617E-04 8,062E-03 ! Notch receptor processing GO:0007220 11 5 1,000 1,617E-04 7,901E-03 ! regulation of activin receptor signaling pathway GO:0032925 15 5 1,000 1,617E-04 7,746E-03 ! skeletal myofibril assembly GO:0014866 12 5 1,000 1,617E-04 7,597E-03 ! cardiac muscle fiber development GO:0048739 12 5 1,000 1,617E-04 7,453E-03 ! positive regulation of transporter activity GO:0032411 8 5 1,000 1,617E-04 7,315E-03 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 1,617E-04 7,182E-03 ! peptidyl-histidine phosphorylation GO:0018106 10 5 1,000 1,617E-04 7,054E-03 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 1,000 1,617E-04 6,93E-03 ! brown fat cell differentiation GO:0050873 7 5 1,000 1,617E-04 6,811E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 1,617E-04 6,695E-03 ! phospholipid scrambling GO:0017121 8 5 1,000 1,617E-04 6,584E-03 ! regulation of interferon-gamma production GO:0032649 43 27 2,000 1,774E-04 7,103E-03 ! response to starvation GO:0042594 47 27 2,000 1,774E-04 6,989E-03 ! actin filament organization GO:0007015 167 72 3,000 2,146E-04 8,323E-03 ! negative regulation of gliogenesis GO:0014014 18 6 1,000 2,419E-04 9,234E-03 GO:0045686|negative regulation of glial cell differentiation, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 2,000 2,44E-04 9,171E-03 ! rhythmic process GO:0048511 142 75 3,000 2,512E-04 9,298E-03 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 2,693E-04 9,821E-03 ! development of primary sexual characteristics GO:0045137 143 80 3,000 3,218E-04 0,01156043 ! prostate gland development GO:0030850 14 7 1,000 3,378E-04 0,0119587 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 3,378E-04 0,01178786 ! regulation of gluconeogenesis GO:0006111 8 7 1,000 3,378E-04 0,01162184 ! amyloid precursor protein catabolic process GO:0042987 15 7 1,000 3,378E-04 0,01146042 ! skeletal muscle contraction GO:0003009 8 7 1,000 3,378E-04 0,01130343 ! peptidyl-histidine modification GO:0018202 17 7 1,000 3,378E-04 0,01115068 ! spliceosome assembly GO:0000245 75 34 2,000 3,554E-04 0,01157623 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 2,000 3,554E-04 0,01142391 ! negative regulation of transport GO:0051051 164 85 3,000 4,056E-04 0,01286726 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 4,492E-04 0,01406762 ! ER overload response GO:0006983 13 8 1,000 4,492E-04 0,01388955 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 4,492E-04 0,01371593 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 4,492E-04 0,0135466 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 1,000 4,492E-04 0,0133814 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 4,574E-04 0,01346231 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 5,759E-04 0,01675037 ! regulation of histone modification GO:0031056 14 9 1,000 5,759E-04 0,01655331 ! microtubule bundle formation GO:0001578 22 9 1,000 5,759E-04 0,01636083 ! amyloid precursor protein metabolic process GO:0042982 18 9 1,000 5,759E-04 0,01617277 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 1,000 5,759E-04 0,01598899 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 5,759E-04 0,01580934 ! mRNA catabolic process GO:0006402 79 41 2,000 6,201E-04 0,01683247 ! sex differentiation GO:0007548 171 96 3,000 6,429E-04 0,01725912 ! regulation of myeloid cell differentiation GO:0045637 105 43 2,000 7,137E-04 0,0189507 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 1,000 7,18E-04 0,01886145 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 7,18E-04 0,01866079 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 7,18E-04 0,01846436 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 1,000 7,18E-04 0,01827203 ! epithelial cell development GO:0002064 21 10 1,000 7,18E-04 0,01808366 ! regulation of gliogenesis GO:0014013 23 10 1,000 7,18E-04 0,01789913 GO:0045685|regulation of glial cell differentiation, ! musculoskeletal movement GO:0050881 16 10 1,000 7,18E-04 0,01771833 GO:0050879|multicellular organismal movement, ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 7,18E-04 0,01754115 ! blastocyst formation GO:0001825 18 10 1,000 7,18E-04 0,01736747 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 8,157E-04 0,0195378 ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 8,157E-04 0,01934811 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 8,752E-04 0,02055982 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 8,752E-04 0,02036402 ! detection of mechanical stimulus GO:0050982 22 11 1,000 8,752E-04 0,0201719 ! keratinocyte proliferation GO:0043616 19 11 1,000 8,752E-04 0,01998338 ! adult heart development GO:0007512 16 11 1,000 8,752E-04 0,01979835 ! temperature homeostasis GO:0001659 18 11 1,000 8,752E-04 0,01961671 ! neuroblast proliferation GO:0007405 25 11 1,000 8,752E-04 0,01943838 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 1,047E-03 0,02303659 ! regulation of B cell proliferation GO:0030888 22 12 1,000 1,048E-03 0,02284867 ! hippocampus development GO:0021766 29 12 1,000 1,048E-03 0,02264647 ! focal adhesion formation GO:0048041 37 12 1,000 1,048E-03 0,02244782 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 1,048E-03 0,02225262 GO:0042130|negative regulation of T cell proliferation, ! localization within membrane GO:0051668 26 12 1,000 1,048E-03 0,02206079 ! positive regulation of lipid metabolic process GO:0045834 30 13 1,000 1,235E-03 0,02578037 ! positive regulation of cell growth GO:0030307 24 13 1,000 1,235E-03 0,02556189 ! plasma membrane organization GO:0007009 27 13 1,000 1,235E-03 0,02534708 ! membrane protein proteolysis GO:0033619 33 13 1,000 1,235E-03 0,02513586 GO:0006509|membrane protein ectodomain proteolysis, ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 1,235E-03 0,02492812 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 35 13 1,000 1,235E-03 0,0247238 ! histone methylation GO:0016571 29 13 1,000 1,235E-03 0,02452279 ! regulation of erythrocyte differentiation GO:0045646 47 13 1,000 1,235E-03 0,02432503 ! regulation of fatty acid oxidation GO:0046320 34 13 1,000 1,235E-03 0,02413042 ! Notch signaling pathway GO:0007219 111 52 2,000 1,244E-03 0,02412845 ! ribonucleoprotein complex assembly GO:0022618 104 52 2,000 1,244E-03 0,02393847 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 1,315E-03 0,02510228 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! negative regulation of caspase activity GO:0043154 23 14 1,000 1,437E-03 0,02720682 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 1,437E-03 0,02699754 ! RNA catabolic process GO:0006401 103 55 2,000 1,464E-03 0,02730676 ! response to UV GO:0009411 120 55 2,000 1,464E-03 0,02709989 ! negative regulation of cell motion GO:0051271 142 55 2,000 1,464E-03 0,02689613 ! cardiac muscle contraction GO:0060048 28 15 1,000 1,653E-03 0,03014093 ! regulation of mRNA processing GO:0050684 26 15 1,000 1,653E-03 0,02991767 ! glycoprotein catabolic process GO:0006516 33 15 1,000 1,653E-03 0,02969768 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,884E-03 0,0336031 ! positive regulation of cell size GO:0045793 29 16 1,000 1,884E-03 0,03335959 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 1,000 1,884E-03 0,0331196 ! regulation of transmembrane transporter activity GO:0022898 27 16 1,000 1,884E-03 0,03288303 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 1,884E-03 0,03264982 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of peptidase activity GO:0010466 28 17 1,000 2,13E-03 0,03664511 ! cardiac muscle tissue development GO:0048738 34 17 1,000 2,13E-03 0,03638885 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 2,13E-03 0,03613615 GO:0031114|regulation of microtubule depolymerization, ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 2,264E-03 0,0381526 ! positive regulation of cell motion GO:0051272 157 65 2,000 2,367E-03 0,03960783 ! limbic system development GO:0021761 40 18 1,000 2,39E-03 0,03971794 ! cell-substrate junction assembly GO:0007044 56 18 1,000 2,39E-03 0,03944957 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 2,39E-03 0,03918481 ! regulation of BMP signaling pathway GO:0030510 33 18 1,000 2,39E-03 0,03892358 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 1,000 2,39E-03 0,03866581 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 2,39E-03 0,03841143 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 2,472E-03 0,03947902 ! negative regulation of cell growth GO:0030308 142 67 2,000 2,581E-03 0,04094044 ! chromosome segregation GO:0007059 127 67 2,000 2,581E-03 0,04067631 ! protein amino acid ADP-ribosylation GO:0006471 37 19 1,000 2,664E-03 0,04171878 ! neuromuscular junction development GO:0007528 43 19 1,000 2,664E-03 0,04145306 ! heart process GO:0003015 32 19 1,000 2,664E-03 0,0411907 GO:0060047|heart contraction, ! negative regulation of cell size GO:0045792 144 69 2,000 2,806E-03 0,04311405 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 2,000 2,806E-03 0,04284459 ! cell redox homeostasis GO:0045454 114 70 2,000 2,923E-03 0,0443542 ! skin development GO:0043588 42 20 1,000 2,952E-03 0,04451912 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 2,952E-03 0,044246 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 2,952E-03 0,04397621 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 2,952E-03 0,04370969 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 2,952E-03 0,04344637 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 2,952E-03 0,04318622 ! regulation of fatty acid metabolic process GO:0019217 45 20 1,000 2,952E-03 0,04292916 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 2,952E-03 0,04267514 ! negative regulation of T cell activation GO:0050868 41 20 1,000 2,952E-03 0,04242411 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 3,043E-03 0,04347459 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 2,000 3,166E-03 0,04496851 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 2,000 3,166E-03 0,04470857 ! lipid phosphorylation GO:0046834 43 21 1,000 3,254E-03 0,04569055 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 1,000 3,254E-03 0,04542946 ! axon guidance GO:0007411 162 75 2,000 3,553E-03 0,04931945 ! cellular response to starvation GO:0009267 37 22 1,000 3,57E-03 0,04927693 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 3,57E-03 0,0490001 ! peptidyl-serine modification GO:0018209 50 22 1,000 3,57E-03 0,04872635 ! sarcomere organization GO:0045214 32 22 1,000 3,57E-03 0,04845565 ! positive regulation of B cell activation GO:0050871 42 22 1,000 3,57E-03 0,04818794 ! protein stabilization GO:0050821 41 22 1,000 3,57E-03 0,04792317 ! positive regulation of ligase activity GO:0051351 130 77 2,000 3,827E-03 0,05108289 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 1,000 3,9E-03 0,05177936 GO:0060415|muscle tissue morphogenesis, ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 4,112E-03 0,05430609 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 4,243E-03 0,05573134 ! pallium development GO:0021543 56 24 1,000 4,243E-03 0,05543331 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 4,243E-03 0,05513845 ! platelet activation GO:0030168 41 24 1,000 4,243E-03 0,05484671 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 4,243E-03 0,05455805 ! activation of protein kinase activity GO:0032147 170 80 2,000 4,26E-03 0,05448915 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 4,6E-03 0,05852927 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 4,6E-03 0,05822601 ! regulation of transmembrane transport GO:0034762 39 25 1,000 4,6E-03 0,05792587 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 4,6E-03 0,05762882 ! regulation of ligase activity GO:0051340 147 84 2,000 4,883E-03 0,06086176 ! myelination GO:0042552 50 26 1,000 4,97E-03 0,061634 ! protein amino acid alkylation GO:0008213 59 26 1,000 4,97E-03 0,06132271 GO:0006479|protein amino acid methylation, ! regulation of cellular ketone metabolic process GO:0010565 51 26 1,000 4,97E-03 0,06101456 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 4,97E-03 0,06070949 ! negative regulation of cell development GO:0010721 83 26 1,000 4,97E-03 0,06040745 GO:0050768|negative regulation of neurogenesis, ! blastocyst development GO:0001824 50 26 1,000 4,97E-03 0,0601084 ! negative regulation of growth GO:0045926 168 85 2,000 5,047E-03 0,06073439 ! regulation of neuron differentiation GO:0045664 187 85 2,000 5,047E-03 0,06043667 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 5,353E-03 0,06379798 ! regulation of chromosome organization GO:0033044 49 27 1,000 5,353E-03 0,06348828 ! cellular response to nutrient levels GO:0031669 45 27 1,000 5,353E-03 0,06318157 ! mitochondrion organization GO:0007005 159 87 2,000 5,384E-03 0,06323805 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 5,75E-03 0,0672125 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 5,75E-03 0,06689244 ! dendrite development GO:0016358 67 28 1,000 5,75E-03 0,06657541 ! fat cell differentiation GO:0045444 57 28 1,000 5,75E-03 0,06626138 ! gland development GO:0048732 220 91 2,000 6,099E-03 0,06995263 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 6,16E-03 0,07031824 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 6,16E-03 0,06999118 ! positive regulation of MAP kinase activity GO:0043406 174 93 2,000 6,477E-03 0,0732524 ! myofibril assembly GO:0030239 50 30 1,000 6,582E-03 0,07410318 GO:0055002|striated muscle cell development, ! cell junction assembly GO:0034329 85 31 1,000 7,018E-03 0,07864221 ! erythrocyte differentiation GO:0030218 62 31 1,000 7,018E-03 0,07828312 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 7,018E-03 0,07792728 ! ensheathment of neurons GO:0007272 64 31 1,000 7,018E-03 0,07757467 GO:0008366|axon ensheathment, ! response to mechanical stimulus GO:0009612 60 32 1,000 7,466E-03 0,08215619 ! muscle cell development GO:0055001 52 32 1,000 7,466E-03 0,08178778 ! peripheral nervous system development GO:0007422 68 32 1,000 7,466E-03 0,08142265 ! regulation of synaptic plasticity GO:0048167 78 35 1,000 8,885E-03 0,09647288 ! positive regulation of endocytosis GO:0045807 56 35 1,000 8,885E-03 0,09604601 ! telencephalon development GO:0021537 81 35 1,000 8,885E-03 0,0956229 ! calcium-mediated signaling GO:0019722 67 35 1,000 8,885E-03 0,0952035 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 9,383E-03 0,10009898 ! actomyosin structure organization GO:0031032 68 37 1,000 9,893E-03 0,10508123 ! cell junction organization GO:0034330 96 37 1,000 9,893E-03 0,10462634 ! regulation of microtubule-based process GO:0032886 86 37 1,000 9,893E-03 0,10417536 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 1,000 0,01041514 0,10920253 ! regulation of protein stability GO:0031647 77 38 1,000 0,01041514 0,10873586 ! glycogen metabolic process GO:0005977 63 38 1,000 0,01041514 0,10827315 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 0,01041514 0,10781437 ! erythrocyte homeostasis GO:0034101 75 39 1,000 0,01094921 0,11286469 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,01094921 0,11239047 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 64 39 1,000 0,01094921 0,11192022 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 1,000 0,01149515 0,11701105 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,01149515 0,11652553 ! regulation of intracellular protein transport GO:0033157 86 42 1,000 0,0126222 0,12742158 ! regulation of T cell differentiation GO:0045580 78 42 1,000 0,0126222 0,12689722 ! epithelial cell differentiation GO:0030855 83 43 1,000 0,0132031 0,13219333 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 1,000 0,0132031 0,13165377 ! striated muscle cell differentiation GO:0051146 91 43 1,000 0,0132031 0,13111859 ! regulation of T cell proliferation GO:0042129 80 43 1,000 0,0132031 0,13058774 ! energy reserve metabolic process GO:0006112 76 44 1,000 0,01379546 0,13589637 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,01379546 0,1353506 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 1,000 0,01379546 0,1348092 ! striated muscle contraction GO:0006941 85 44 1,000 0,01379546 0,13427211 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 0,01439916 0,13959189 ! keratinocyte differentiation GO:0030216 81 45 1,000 0,01439916 0,13904015 ! biopolymer methylation GO:0043414 91 45 1,000 0,01439916 0,13849275 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 1,000 0,01501412 0,14384118 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,01501412 0,1432793 ! regulation of JNK cascade GO:0046328 104 47 1,000 0,01564023 0,14867349 ! response to insulin stimulus GO:0032868 98 47 1,000 0,01564023 0,14809724 ! positive regulation of cell cycle GO:0045787 96 48 1,000 0,01627739 0,15353542 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 1,000 0,01627739 0,1529449 ! methylation GO:0032259 97 48 1,000 0,01627739 0,1523589 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,01692551 0,15782068 ! JNK cascade GO:0007254 106 49 1,000 0,01692551 0,1572206 ! regulation of action potential GO:0001508 102 50 1,000 0,01758448 0,16272304 ! epidermal cell differentiation GO:0009913 87 50 1,000 0,01758448 0,16210899 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 0,01825421 0,16765049 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,01825421 0,16702259 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,0189346 0,17260159 ! histone modification GO:0016570 104 52 1,000 0,0189346 0,17195994 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 0,0189346 0,17132305 ! respiratory electron transport chain GO:0022904 83 53 1,000 0,01962555 0,17691967 ! positive regulation of growth GO:0045927 96 53 1,000 0,01962555 0,17626923 ! chromatin remodeling GO:0006338 122 53 1,000 0,01962555 0,17562355 ! synapse organization GO:0050808 102 53 1,000 0,01962555 0,17498259 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02009424 0,17850989 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02009424 0,17786312 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02009424 0,17722101 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02009424 0,17658353 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02009424 0,17595061 ! neuron fate determination GO:0048664 7 5 0,000 0,02009424 0,17532222 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02009424 0,17469829 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02009424 0,1740788 ! polyol transport GO:0015791 12 5 0,000 0,02009424 0,17346368 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02009424 0,17285289 ! response to superoxide GO:0000303 10 5 0,000 0,02009424 0,17224639 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02009424 0,17164413 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02009424 0,17104607 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02009424 0,17045216 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02009424 0,16986236 ! female meiosis GO:0007143 10 5 0,000 0,02009424 0,16927662 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02009424 0,16869492 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02009424 0,16811719 ! hypothalamus development GO:0021854 9 5 0,000 0,02009424 0,16754342 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02009424 0,16697354 ! cobalt ion transport GO:0006824 11 5 0,000 0,02009424 0,16640753 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02009424 0,16584534 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02009424 0,16528694 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02009424 0,16473228 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02009424 0,16418134 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02009424 0,16363407 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02009424 0,16309043 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02009424 0,1625504 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02009424 0,16201393 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02009424 0,16148099 ! transposition GO:0032196 9 5 0,000 0,02009424 0,16095154 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02009424 0,16042556 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,02009424 0,159903 ! negative chemotaxis GO:0050919 16 5 0,000 0,02009424 0,15938383 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02009424 0,15886803 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02009424 0,15835555 ! behavioral response to pain GO:0048266 10 5 0,000 0,02009424 0,15784637 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02009424 0,15734045 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02009424 0,15683777 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02009424 0,15633828 ! micturition GO:0060073 9 5 0,000 0,02009424 0,15584197 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02009424 0,1553488 ! copulation GO:0007620 9 5 0,000 0,02009424 0,15485874 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02009424 0,15437176 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02009424 0,15388784 ! bioluminescence GO:0008218 9 5 0,000 0,02009424 0,15340694 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02009424 0,15292904 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02009424 0,1524541 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02009424 0,15198211 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02009424 0,15151303 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02009424 0,15104683 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02009424 0,1505835 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02009424 0,150123 ! grooming behavior GO:0007625 6 5 0,000 0,02009424 0,14966531 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02009424 0,1492104 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02009424 0,14875824 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02009424 0,14830882 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02009424 0,14786211 ! response to protozoan GO:0001562 13 5 0,000 0,02009424 0,14741808 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,02009424 0,14697671 ! lymph vessel development GO:0001945 10 5 0,000 0,02009424 0,14653797 ! endochondral ossification GO:0001958 17 5 0,000 0,02009424 0,14610185 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02009424 0,14566831 ! single strand break repair GO:0000012 8 5 0,000 0,02009424 0,14523734 ! parathyroid gland development GO:0060017 14 5 0,000 0,02009424 0,14480891 ! anagen GO:0042640 7 5 0,000 0,02009424 0,144383 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02009424 0,14395959 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02009424 0,14353866 ! cytokine secretion GO:0050663 15 5 0,000 0,02009424 0,14312018 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02009424 0,14270413 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02009424 0,14229049 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02009424 0,14187925 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02009424 0,14147038 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02009424 0,14106385 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02009424 0,14065966 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02009424 0,14025777 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,02009424 0,13985818 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02009424 0,13946085 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02009424 0,13906578 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02009424 0,13867294 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02009424 0,13828231 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02009424 0,13789388 ! microvillus organization GO:0032528 8 5 0,000 0,02009424 0,13750762 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,02009424 0,13712352 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02009424 0,13674156 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02009424 0,13636172 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02009424 0,13598399 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02009424 0,13560834 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02009424 0,13523477 ! polyol catabolic process GO:0046174 9 5 0,000 0,02009424 0,13486324 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02009424 0,13449376 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02009424 0,13412629 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02009424 0,13376082 ! muscle cell migration GO:0014812 8 5 0,000 0,02009424 0,13339734 ! mitochondrial fission GO:0000266 8 5 0,000 0,02009424 0,13303583 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02009424 0,13267627 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02009424 0,13231865 ! mRNA transcription GO:0009299 10 5 0,000 0,02009424 0,13196296 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02009424 0,13160917 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02009424 0,13125727 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02009424 0,13090726 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02009424 0,1305591 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02009424 0,13021279 ! monocyte activation GO:0042117 10 5 0,000 0,02009424 0,12986831 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02009424 0,12952565 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02009424 0,12918479 ! response to food GO:0032094 6 5 0,000 0,02009424 0,12884572 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02009424 0,12850843 ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02009424 0,1281729 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02009424 0,12783912 ! forebrain neuron development GO:0021884 13 5 0,000 0,02009424 0,12750707 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02009424 0,12717674 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02009424 0,12684812 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02009424 0,12652119 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02009424 0,12619594 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02009424 0,12587236 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02009424 0,12555044 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02009424 0,12523015 ! lipid glycosylation GO:0030259 7 5 0,000 0,02009424 0,1249115 ! nucleobase transport GO:0015851 6 5 0,000 0,02009424 0,12459447 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02009424 0,12427904 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02009424 0,1239652 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02009424 0,12365295 ! basic amino acid transport GO:0015802 12 5 0,000 0,02009424 0,12334226 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02009424 0,12303313 ! actin nucleation GO:0045010 11 5 0,000 0,02009424 0,12272555 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02009424 0,1224195 ! depurination GO:0045007 5 5 0,000 0,02009424 0,12211498 ! depyrimidination GO:0045008 10 5 0,000 0,02009424 0,12181196 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02009424 0,12151045 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02009424 0,12121042 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02009424 0,12091187 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02009424 0,12061479 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02009424 0,12031917 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,02009424 0,12002499 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02009424 0,11973225 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02009424 0,11944093 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02009424 0,11915102 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02009424 0,11886252 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02009424 0,11857541 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02009424 0,11828969 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02009424 0,11800534 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02009424 0,11772235 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02009424 0,11744072 ! response to arsenic GO:0046685 11 5 0,000 0,02009424 0,11716043 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02009424 0,11688148 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02009424 0,11660385 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02009424 0,11632754 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02009424 0,11605253 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02009424 0,11577882 ! response to mercury ion GO:0046689 8 5 0,000 0,02009424 0,1155064 ! response to cadmium ion GO:0046686 7 5 0,000 0,02009424 0,11523526 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02009424 0,11496539 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02009424 0,11469678 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02009424 0,11442942 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02009424 0,1141633 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02009424 0,11389842 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02009424 0,11363477 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02009424 0,11337233 ! decidualization GO:0046697 11 5 0,000 0,02009424 0,11311111 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02009424 0,11285108 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02009424 0,11259225 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02009424 0,1123346 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02009424 0,11207813 ! embryonic cleavage GO:0040016 6 5 0,000 0,02009424 0,11182283 ! peroxisome fission GO:0016559 5 5 0,000 0,02009424 0,11156868 ! histone demethylation GO:0016577 13 5 0,000 0,02009424 0,11131569 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02009424 0,11106385 ! mitotic recombination GO:0006312 9 5 0,000 0,02009424 0,11081314 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02009424 0,11056356 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02009424 0,1103151 ! metaphase plate congression GO:0051310 7 5 0,000 0,02009424 0,11006776 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02009424 0,10982152 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02009424 0,10957639 ! enteric nervous system development GO:0048484 8 5 0,000 0,02009424 0,10933234 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02009424 0,10908938 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02009424 0,1088475 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02009424 0,10860668 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02009424 0,10836693 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02009424 0,10812824 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02009424 0,10789059 ! B cell homeostasis GO:0001782 13 5 0,000 0,02009424 0,10765399 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02009424 0,10741843 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02009424 0,10718389 ! metaphase GO:0051323 11 5 0,000 0,02009424 0,10695037 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02009424 0,10671787 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02009424 0,10648638 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02009424 0,10625589 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02009424 0,10602639 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02009424 0,10579789 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02009424 0,10557037 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02009424 0,10534382 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02009424 0,10511825 ! response to redox state GO:0051775 6 5 0,000 0,02009424 0,10489363 GO:0006980|redox signal response, ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02009424 0,10466998 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02009424 0,10444728 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02009424 0,10422552 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02009424 0,1040047 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02009424 0,10378482 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02009424 0,10356587 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02009424 0,10334783 ! striatum development GO:0021756 14 5 0,000 0,02009424 0,10313072 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02009424 0,10291451 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02009424 0,10269921 ! glial cell migration GO:0008347 10 5 0,000 0,02009424 0,1024848 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02009424 0,10227129 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02009424 0,10205867 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02009424 0,10184693 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02009424 0,10163607 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02009424 0,10142608 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02009424 0,10121695 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02009424 0,10100868 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02009424 0,10080127 ! neuroprotection GO:0043526 8 5 0,000 0,02009424 0,10059471 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02009424 0,100389 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02009424 0,10018412 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02009424 0,09998008 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02009424 0,09977687 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02009424 0,09957448 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02009424 0,09937292 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02009424 0,09917216 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02009424 0,09897222 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02009424 0,09877308 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02009424 0,09857474 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02009424 0,0983772 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02009424 0,09818044 ! spindle assembly GO:0051225 6 5 0,000 0,02009424 0,09798447 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02009424 0,09778928 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02009424 0,09759487 ! protein palmitoylation GO:0018345 12 5 0,000 0,02009424 0,09740123 ! drug metabolic process GO:0017144 7 5 0,000 0,02009424 0,09720836 ! stem cell division GO:0017145 11 5 0,000 0,02009424 0,09701625 GO:0048103|somatic stem cell division, ! organ regeneration GO:0031100 7 5 0,000 0,02009424 0,09682489 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02009424 0,09663429 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02009424 0,09644444 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,02032698 0,09737022 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,02032698 0,09717967 GO:0010863|positive regulation of phospholipase C activity, ! covalent chromatin modification GO:0016569 115 54 1,000 0,02032698 0,09698987 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,02103878 0,10019053 ! cell maturation GO:0048469 107 55 1,000 0,02103878 0,09999561 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,02176086 0,10322677 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,02176086 0,10302672 ! muscle fiber development GO:0048747 131 57 1,000 0,02249313 0,10628766 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,02249313 0,10608247 ! heart morphogenesis GO:0003007 105 57 1,000 0,02249313 0,10587807 ! regulation of intracellular transport GO:0032386 108 57 1,000 0,02249313 0,10567446 ! positive regulation of cell migration GO:0030335 137 58 1,000 0,02323549 0,10895261 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,02323549 0,10874389 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,02323549 0,10853597 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,02323549 0,10832884 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,0240647 0,11198109 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,0240647 0,1117682 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,0240647 0,11155611 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,0240647 0,11134483 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,0240647 0,11113435 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,0240647 0,11092466 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,0240647 0,11071577 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,0240647 0,11050765 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,0240647 0,11030032 ! response to oxygen radical GO:0000305 11 6 0,000 0,0240647 0,11009377 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,0240647 0,10988798 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,0240647 0,10968297 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,0240647 0,10947872 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,0240647 0,10927523 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,0240647 0,10907249 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,0240647 0,1088705 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,0240647 0,10866926 ! forebrain regionalization GO:0021871 9 6 0,000 0,0240647 0,10846877 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,0240647 0,10826901 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,0240647 0,10806998 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,0240647 0,10787169 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,0240647 0,10767412 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,0240647 0,10747728 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,0240647 0,10728115 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,0240647 0,10708574 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,0240647 0,10689104 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,0240647 0,10669704 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,0240647 0,10650375 ! malate metabolic process GO:0006108 13 6 0,000 0,0240647 0,10631116 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,0240647 0,10611926 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,0240647 0,10592806 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,0240647 0,10573754 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,0240647 0,10554771 ! protein refolding GO:0042026 15 6 0,000 0,0240647 0,10535855 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,0240647 0,10517007 ! opsonization GO:0008228 8 6 0,000 0,0240647 0,10498227 ! mating behavior GO:0007617 7 6 0,000 0,0240647 0,10479514 ! erythrocyte maturation GO:0043249 8 6 0,000 0,0240647 0,10460867 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,0240647 0,10442286 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,0240647 0,10423772 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,0240647 0,10405322 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,0240647 0,10386938 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,0240647 0,10368619 ! response to interferon-gamma GO:0034341 16 6 0,000 0,0240647 0,10350365 ! toxin metabolic process GO:0009404 11 6 0,000 0,0240647 0,10332174 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,0240647 0,10314048 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,0240647 0,10295985 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,0240647 0,10277985 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,0240647 0,10260047 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,0240647 0,10242173 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,0240647 0,1022436 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,0240647 0,1020661 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,0240647 0,10188921 ! thymic T cell selection GO:0045061 16 6 0,000 0,0240647 0,10171293 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,0240647 0,10153726 ! protein lipoylation GO:0009249 10 6 0,000 0,0240647 0,10136219 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,0240647 0,10118773 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,0240647 0,10101387 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,0240647 0,1008406 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,0240647 0,10066793 ! glutamate catabolic process GO:0006538 12 6 0,000 0,0240647 0,10049585 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,0240647 0,10032435 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,0240647 0,10015344 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,0240647 0,09998312 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,0240647 0,09981336 ! hyperosmotic response GO:0006972 10 6 0,000 0,0240647 0,09964419 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,0240647 0,09947559 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,0240647 0,09930755 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,0240647 0,09914009 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,0240647 0,09897318 ! urea metabolic process GO:0019627 7 6 0,000 0,0240647 0,09880684 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,0240647 0,09864106 ! neutrophil activation GO:0042119 7 6 0,000 0,0240647 0,09847583 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,0240647 0,09831116 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,0240647 0,09814703 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,0240647 0,09798345 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,0240647 0,09782042 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,0240647 0,09765793 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,0240647 0,09749597 ! neuron apoptosis GO:0051402 15 6 0,000 0,0240647 0,09733456 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,0240647 0,09717367 ! T cell mediated immunity GO:0002456 17 6 0,000 0,0240647 0,09701332 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,0240647 0,0968535 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,0240647 0,0966942 ! carnitine transport GO:0015879 10 6 0,000 0,0240647 0,09653542 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0240647 0,09637717 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,0240647 0,09621943 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,0240647 0,09606221 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,0240647 0,0959055 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,0240647 0,0957493 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,0240647 0,09559361 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,0240647 0,09543843 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,0240647 0,09528375 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,0240647 0,09512957 ! establishment of spindle localization GO:0051293 16 6 0,000 0,0240647 0,09497588 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,0240647 0,0948227 ! neural nucleus development GO:0048857 19 6 0,000 0,0240647 0,09467 ! response to UV-C GO:0010225 14 6 0,000 0,0240647 0,0945178 ! astrocyte development GO:0014002 16 6 0,000 0,0240647 0,09436609 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,0240647 0,09421486 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,0240647 0,09406411 ! interaction with symbiont GO:0051702 14 6 0,000 0,0240647 0,09391385 ! regulation of dendrite development GO:0050773 16 6 0,000 0,0240647 0,09376407 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,0240647 0,09361476 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,0240647 0,09346593 ! response to copper ion GO:0046688 10 6 0,000 0,0240647 0,09331757 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,0240647 0,09316969 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,0240647 0,09302227 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0240647 0,09287531 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,0240647 0,09272882 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,0240647 0,09258279 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,0240647 0,09243722 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0240647 0,09229211 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,0240647 0,09214745 ! hair follicle maturation GO:0048820 8 6 0,000 0,0240647 0,09200324 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,0240647 0,09185949 ! Schwann cell development GO:0014044 15 6 0,000 0,0240647 0,09171618 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,0240647 0,09157332 ! response to pheromone GO:0019236 6 6 0,000 0,0240647 0,0914309 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,0240647 0,09128893 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,0240647 0,0911474 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,0240647 0,0910063 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,0240647 0,09086564 ! subpallium development GO:0021544 15 6 0,000 0,0240647 0,09072542 ! neural tube patterning GO:0021532 8 6 0,000 0,0240647 0,09058563 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,0240647 0,09044626 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,0240647 0,09030733 ! maintenance of organ identity GO:0048496 9 6 0,000 0,0240647 0,09016882 ! G2 phase GO:0051319 16 6 0,000 0,0240647 0,09003074 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,0240647 0,08989308 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,0240647 0,08975583 ! oxygen homeostasis GO:0032364 10 6 0,000 0,0240647 0,08961901 ! establishment of planar polarity GO:0001736 7 6 0,000 0,0240647 0,08948261 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,0240647 0,08934661 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,0240647 0,08921103 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,0240647 0,08907587 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,0240647 0,08894111 ! receptor internalization GO:0031623 11 6 0,000 0,0240647 0,08880675 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,0240647 0,08867281 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,0240647 0,08853926 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,0240647 0,08840612 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0240647 0,08827338 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,0240647 0,08814104 ! protein deubiquitination GO:0016579 16 6 0,000 0,0240647 0,08800909 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,0240647 0,08787754 ! protein destabilization GO:0031648 9 6 0,000 0,0240647 0,08774638 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,0240647 0,08761561 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,0240647 0,08748523 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,0240647 0,08735523 ! regulation of viral transcription GO:0046782 11 6 0,000 0,0240647 0,08722563 ! progesterone metabolic process GO:0042448 12 6 0,000 0,0240647 0,0870964 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,0240647 0,08696756 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,0240647 0,0868391 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,0240647 0,08671102 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,0240647 0,08658332 ! determination of adult lifespan GO:0008340 17 6 0,000 0,0240647 0,08645599 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,0240647 0,08632903 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,0240647 0,08620245 ! neural plate development GO:0001840 9 6 0,000 0,0240647 0,08607624 ! catecholamine transport GO:0051937 9 6 0,000 0,0240647 0,0859504 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,0240647 0,08582492 ! sensory cilium assembly GO:0035058 10 6 0,000 0,0240647 0,08569981 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,0240647 0,08557507 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,0240647 0,08545069 ! maternal placenta development GO:0001893 12 6 0,000 0,0240647 0,08532666 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,0240647 0,085203 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,0240647 0,0850797 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,0240647 0,08495675 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,0240647 0,08483416 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,0240647 0,08471192 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,0240647 0,08459003 GO:0055081|anion homeostasis, ! lipid modification GO:0030258 112 60 1,000 0,02475013 0,08687438 ! regulation of endocytosis GO:0030100 104 60 1,000 0,02475013 0,08674973 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 0,02630404 0,09206413 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,02630404 0,09193242 ! regulation of protein complex assembly GO:0043254 132 63 1,000 0,02709549 0,09456326 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 0,02789649 0,09721986 ! tRNA transcription GO:0009304 17 7 0,000 0,02801919 0,09750839 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,02801919 0,09736969 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,02801919 0,09723138 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02801919 0,09709346 ! regulation of helicase activity GO:0051095 16 7 0,000 0,02801919 0,09695594 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,02801919 0,0968188 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,02801919 0,09668205 ! sleep GO:0030431 16 7 0,000 0,02801919 0,09654569 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02801919 0,09640971 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,02801919 0,09627411 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02801919 0,09613889 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,02801919 0,09600406 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02801919 0,0958696 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02801919 0,09573551 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,02801919 0,0956018 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02801919 0,09546847 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,02801919 0,0953355 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,02801919 0,09520291 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02801919 0,09507068 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,02801919 0,09493882 ! glycolipid transport GO:0046836 11 7 0,000 0,02801919 0,09480733 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02801919 0,0946762 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,02801919 0,09454543 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,02801919 0,09441502 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02801919 0,09428498 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02801919 0,09415528 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,02801919 0,09402595 ! mRNA stabilization GO:0048255 18 7 0,000 0,02801919 0,09389697 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,02801919 0,09376835 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,02801919 0,09364007 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,02801919 0,09351215 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,02801919 0,09338457 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02801919 0,09325735 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02801919 0,09313047 ! lipoprotein transport GO:0042953 14 7 0,000 0,02801919 0,09300393 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,02801919 0,09287774 ! rhythmic behavior GO:0007622 17 7 0,000 0,02801919 0,09275189 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,02801919 0,09262638 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,02801919 0,09250121 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,02801919 0,09237637 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,02801919 0,09225188 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02801919 0,09212771 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,02801919 0,09200389 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02801919 0,09188039 ! mechanosensory behavior GO:0007638 16 7 0,000 0,02801919 0,09175723 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,02801919 0,09163439 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,02801919 0,09151189 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,02801919 0,09138971 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,02801919 0,09126786 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02801919 0,09114633 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02801919 0,09102512 ! spinal cord patterning GO:0021511 14 7 0,000 0,02801919 0,09090424 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,02801919 0,09078368 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,02801919 0,09066343 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02801919 0,09054351 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,02801919 0,0904239 ! adrenal gland development GO:0030325 17 7 0,000 0,02801919 0,09030461 ! cysteine metabolic process GO:0006534 13 7 0,000 0,02801919 0,09018563 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,02801919 0,09006696 ! ovulation GO:0030728 10 7 0,000 0,02801919 0,08994861 ! adenohypophysis development GO:0021984 11 7 0,000 0,02801919 0,08983057 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,02801919 0,08971283 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,02801919 0,08959541 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,02801919 0,08947829 ! microtubule nucleation GO:0007020 21 7 0,000 0,02801919 0,08936148 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02801919 0,08924497 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,02801919 0,08912877 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02801919 0,08901286 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,02801919 0,08889726 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,02801919 0,08878196 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02801919 0,08866696 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,02801919 0,08855225 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,02801919 0,08843784 ! galactose metabolic process GO:0006012 13 7 0,000 0,02801919 0,08832373 ! vesicle fusion GO:0006906 20 7 0,000 0,02801919 0,08820991 ! response to dietary excess GO:0002021 8 7 0,000 0,02801919 0,08809639 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02801919 0,08798315 ! intracellular pH reduction GO:0051452 13 7 0,000 0,02801919 0,08787021 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02801919 0,08775755 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,02801919 0,08764519 ! organ growth GO:0035265 15 7 0,000 0,02801919 0,08753311 ! nucleoside transport GO:0015858 11 7 0,000 0,02801919 0,08742132 ! nucleoside salvage GO:0043174 11 7 0,000 0,02801919 0,08730981 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,02801919 0,08719859 ! male sex determination GO:0030238 15 7 0,000 0,02801919 0,08708765 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,02801919 0,08697699 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,02801919 0,08686661 ! parturition GO:0007567 16 7 0,000 0,02801919 0,08675652 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,02801919 0,0866467 ! rRNA modification GO:0000154 14 7 0,000 0,02801919 0,08653716 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,02801919 0,08642789 ! spindle checkpoint GO:0031577 16 7 0,000 0,02801919 0,08631891 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,02801919 0,08621019 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,02801919 0,08610175 ! monocyte differentiation GO:0030224 16 7 0,000 0,02801919 0,08599358 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,02801919 0,08588569 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,02801919 0,08577806 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,02801919 0,0856707 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,02801919 0,08556361 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,02801919 0,08545679 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02801919 0,08535024 ! fibrinolysis GO:0042730 11 7 0,000 0,02801919 0,08524395 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,02801919 0,08513793 ! eating behavior GO:0042755 8 7 0,000 0,02801919 0,08503216 ! B cell lineage commitment GO:0002326 21 7 0,000 0,02801919 0,08492667 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02801919 0,08482143 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,02801919 0,08471645 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,02801919 0,08461173 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02801919 0,08450727 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,02801919 0,08440307 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02801919 0,08429913 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,02801919 0,08419544 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,02801919 0,084092 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,02801919 0,08398882 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,02801919 0,0838859 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02801919 0,08378322 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,02801919 0,0836808 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02801919 0,08357862 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02801919 0,0834767 ! histone ubiquitination GO:0016574 9 7 0,000 0,02801919 0,08337502 ! regulation of meiosis GO:0040020 12 7 0,000 0,02801919 0,08327359 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,02801919 0,08317241 ! T cell lineage commitment GO:0002360 16 7 0,000 0,02801919 0,08307147 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,02801919 0,08297078 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02801919 0,08287033 ! membrane to membrane docking GO:0022614 14 7 0,000 0,02801919 0,08277012 ! transcription termination GO:0006353 14 7 0,000 0,02801919 0,08267016 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02801919 0,08257044 ! anaphase GO:0051322 18 7 0,000 0,02801919 0,08247095 GO:0000090|mitotic anaphase, ! axonal fasciculation GO:0007413 19 7 0,000 0,02801919 0,08237171 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,02801919 0,08227271 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,02801919 0,08217394 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,02801919 0,08207541 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,02801919 0,08197712 ! diuresis GO:0030146 12 7 0,000 0,02801919 0,08187906 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02801919 0,08178123 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02801919 0,08168364 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02801919 0,08158628 ! antibiotic transport GO:0042891 9 7 0,000 0,02801919 0,08148916 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02801919 0,08139226 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,02801919 0,0812956 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,02801919 0,08119916 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,02801919 0,08110295 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,02801919 0,08100697 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,02801919 0,08091122 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,02801919 0,08081569 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02801919 0,08072039 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02801919 0,08062531 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,02801919 0,08053046 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,02801919 0,08043583 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,02801919 0,08034142 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,02801919 0,08024724 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,02801919 0,08015327 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,02801919 0,08005952 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,02801919 0,079966 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,02801919 0,07987269 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,02801919 0,07977959 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02801919 0,07968672 ! muscle adaptation GO:0043500 13 7 0,000 0,02801919 0,07959406 ! embryonic heart tube development GO:0035050 14 7 0,000 0,02801919 0,07950162 ! retina homeostasis GO:0001895 12 7 0,000 0,02801919 0,07940939 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,02801919 0,07931737 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,02801919 0,07922557 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,02801919 0,07913398 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,02801919 0,0790426 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 0,02952677 0,08319944 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 1,000 0,03035588 0,08543712 ! myeloid cell differentiation GO:0030099 126 67 1,000 0,03035588 0,0853388 ! regulation of cellular response to stress GO:0080135 142 68 1,000 0,03119418 0,0875947 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,03119418 0,08749413 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 1,000 0,03119418 0,0873938 ! regulation of lipase activity GO:0060191 137 68 1,000 0,03119418 0,08729369 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,03119418 0,08719381 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,03195777 0,0892261 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,03195777 0,08912424 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,03195777 0,08902262 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,03195777 0,08892123 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,03195777 0,08882007 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03195777 0,08871913 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03195777 0,08861843 ! male meiosis GO:0007140 9 8 0,000 0,03195777 0,08851796 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,03195777 0,08841771 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,03195777 0,08831769 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,03195777 0,0882179 ! meiotic prophase I GO:0007128 14 8 0,000 0,03195777 0,08811833 ! response to zinc ion GO:0010043 12 8 0,000 0,03195777 0,08801898 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,03195777 0,08791986 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03195777 0,08782096 ! oligopeptide transport GO:0006857 16 8 0,000 0,03195777 0,08772229 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,03195777 0,08762384 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,03195777 0,0875256 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,03195777 0,08742759 ! signal peptide processing GO:0006465 12 8 0,000 0,03195777 0,0873298 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,03195777 0,08723222 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,03195777 0,08713486 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03195777 0,08703772 ! succinate metabolic process GO:0006105 17 8 0,000 0,03195777 0,0869408 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,03195777 0,08684409 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,03195777 0,0867476 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03195777 0,08665132 ! estrogen metabolic process GO:0008210 17 8 0,000 0,03195777 0,08655525 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,03195777 0,0864594 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03195777 0,08636376 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,03195777 0,08626833 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03195777 0,08617311 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03195777 0,0860781 ! reflex GO:0060004 17 8 0,000 0,03195777 0,0859833 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03195777 0,08588871 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,03195777 0,08579433 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03195777 0,08570015 ! pigment granule organization GO:0048753 17 8 0,000 0,03195777 0,08560618 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03195777 0,08551242 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,03195777 0,08541886 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,03195777 0,08532551 ! astrocyte differentiation GO:0048708 19 8 0,000 0,03195777 0,08523236 ! histidine catabolic process GO:0006548 10 8 0,000 0,03195777 0,08513941 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03195777 0,08504666 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,03195777 0,08495412 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,03195777 0,08486178 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,03195777 0,08476964 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,03195777 0,0846777 ! melanin metabolic process GO:0006582 17 8 0,000 0,03195777 0,08458596 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,03195777 0,08449441 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,03195777 0,08440307 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,03195777 0,08431192 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03195777 0,08422097 ! macrophage activation GO:0042116 13 8 0,000 0,03195777 0,08413021 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03195777 0,08403965 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03195777 0,08394929 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,03195777 0,08385912 ! purine salvage GO:0043101 12 8 0,000 0,03195777 0,08376914 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,03195777 0,08367935 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03195777 0,08358976 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,03195777 0,08350036 ! osteoblast development GO:0002076 17 8 0,000 0,03195777 0,08341115 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,03195777 0,08332213 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,03195777 0,0832333 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,03195777 0,08314466 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,03195777 0,08305621 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03195777 0,08296795 ! response to UV-B GO:0010224 17 8 0,000 0,03195777 0,08287987 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,03195777 0,08279198 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03195777 0,08270428 ! intermediate filament organization GO:0045109 12 8 0,000 0,03195777 0,08261676 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,03195777 0,08252943 ! cellular extravasation GO:0045123 13 8 0,000 0,03195777 0,08244228 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,03195777 0,08235531 ! response to antibiotic GO:0046677 11 8 0,000 0,03195777 0,08226853 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,03195777 0,08218193 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,03195777 0,08209552 ! DNA topological change GO:0006265 12 8 0,000 0,03195777 0,08200928 ! response to tropane GO:0014073 15 8 0,000 0,03195777 0,08192323 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,03195777 0,08183736 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,03195777 0,08175166 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03195777 0,08166615 ! mast cell activation GO:0045576 14 8 0,000 0,03195777 0,08158081 ! multicellular organismal aging GO:0010259 20 8 0,000 0,03195777 0,08149565 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,03195777 0,08141068 ! gas homeostasis GO:0033483 14 8 0,000 0,03195777 0,08132587 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,03195777 0,08124125 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,03195777 0,0811568 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,03195777 0,08107252 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03195777 0,08098842 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03195777 0,08090449 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,03195777 0,08082074 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03195777 0,08073716 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,03195777 0,08065376 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,03195777 0,08057052 ! intracellular lipid transport GO:0032365 16 8 0,000 0,03195777 0,08048746 ! response to tumor cell GO:0002347 16 8 0,000 0,03195777 0,08040457 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03195777 0,08032185 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,03195777 0,0802393 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,03195777 0,08015692 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03195777 0,0800747 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,03195777 0,07999266 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,03195777 0,07991079 ! hormone catabolic process GO:0042447 17 8 0,000 0,03195777 0,07982908 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,03195777 0,07974754 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,03195777 0,07966616 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,03195777 0,07958495 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,03195777 0,07950391 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03195777 0,07942303 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,03195777 0,07934231 ! adult feeding behavior GO:0008343 10 8 0,000 0,03195777 0,07926176 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,03195777 0,07918138 ! ATP catabolic process GO:0006200 11 8 0,000 0,03195777 0,07910115 ! blastocyst growth GO:0001832 19 8 0,000 0,03195777 0,07902109 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03195777 0,07894119 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03195777 0,07886145 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,03195777 0,07878187 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03195777 0,07870246 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,03195777 0,0786232 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,03195777 0,0785441 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,03195777 0,07846516 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,03195777 0,07838638 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,03195777 0,07830776 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,03195777 0,0782293 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03195777 0,07815099 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,03195777 0,07807284 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,03195777 0,07799484 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03195777 0,077917 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,03195777 0,07783932 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,03195777 0,07776179 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03195777 0,07768442 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,03195777 0,07760719 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,03195777 0,07753013 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,03195777 0,07745321 ! lung development GO:0030324 165 69 1,000 0,03204159 0,07757939 ! urogenital system development GO:0001655 149 69 1,000 0,03204159 0,07750258 ! homeostasis of number of cells GO:0048872 131 69 1,000 0,03204159 0,07742592 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,03204159 0,07734941 ! developmental maturation GO:0021700 128 69 1,000 0,03204159 0,07727306 ! protein maturation by peptide bond cleavage GO:0051605 118 70 1,000 0,03289802 0,07926022 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,03463759 0,0833691 ! respiratory tube development GO:0030323 171 72 1,000 0,03463759 0,08328704 ! axon extension GO:0048675 16 9 0,000 0,0358805 0,08619082 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,0358805 0,08610615 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,0358805 0,08602165 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0358805 0,08593732 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,0358805 0,08585315 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,0358805 0,08576914 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,0358805 0,0856853 ! reproductive behavior GO:0019098 22 9 0,000 0,0358805 0,08560162 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0358805 0,08551811 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,0358805 0,08543476 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,0358805 0,08535157 ! UTP metabolic process GO:0046051 10 9 0,000 0,0358805 0,08526854 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,0358805 0,08518568 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,0358805 0,08510297 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,0358805 0,08502043 ! artery development GO:0060840 25 9 0,000 0,0358805 0,08493805 GO:0048844|artery morphogenesis, ! regulation of glycolysis GO:0006110 20 9 0,000 0,0358805 0,08485582 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,0358805 0,08477376 ! equilibrioception GO:0050957 20 9 0,000 0,0358805 0,08469185 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,0358805 0,0846101 ! chemosensory behavior GO:0007635 21 9 0,000 0,0358805 0,08452851 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,0358805 0,08444707 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0358805 0,0843658 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,0358805 0,08428468 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,0358805 0,08420371 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,0358805 0,0841229 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,0358805 0,08404225 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,0358805 0,08396175 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0358805 0,0838814 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,0358805 0,08380121 ! protein targeting to ER GO:0045047 25 9 0,000 0,0358805 0,08372117 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,0358805 0,08364128 ! T cell selection GO:0045058 27 9 0,000 0,0358805 0,08356155 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,0358805 0,08348196 ! glycine catabolic process GO:0006546 15 9 0,000 0,0358805 0,08340253 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,0358805 0,08332325 ! endosome organization GO:0007032 20 9 0,000 0,0358805 0,08324412 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0358805 0,08316515 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,0358805 0,08308632 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0358805 0,08300764 ! mannose metabolic process GO:0006013 13 9 0,000 0,0358805 0,0829291 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,0358805 0,08285072 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,0358805 0,08277249 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,0358805 0,0826944 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,0358805 0,08261646 ! receptor clustering GO:0043113 20 9 0,000 0,0358805 0,08253867 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,0358805 0,08246102 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0358805 0,08238352 ! retinol metabolic process GO:0042572 20 9 0,000 0,0358805 0,08230616 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,0358805 0,08222895 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,0358805 0,08215189 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,0358805 0,08207497 ! macrophage differentiation GO:0030225 15 9 0,000 0,0358805 0,08199819 ! oligodendrocyte development GO:0014003 11 9 0,000 0,0358805 0,08192155 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,0358805 0,08184506 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0358805 0,08176872 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,0358805 0,08169251 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0358805 0,08161645 ! response to amine stimulus GO:0014075 13 9 0,000 0,0358805 0,08154052 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0358805 0,08146474 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,0358805 0,0813891 ! erythrocyte development GO:0048821 17 9 0,000 0,0358805 0,0813136 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,0358805 0,08123824 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,0358805 0,08116302 ! renal water homeostasis GO:0003091 15 9 0,000 0,0358805 0,08108794 ! postreplication repair GO:0006301 25 9 0,000 0,0358805 0,081013 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,0358805 0,08093819 ! icosanoid secretion GO:0032309 15 9 0,000 0,0358805 0,08086353 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0358805 0,080789 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,0358805 0,08071461 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,0358805 0,08064035 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,0358805 0,08056623 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,0358805 0,08049225 ! sterol catabolic process GO:0016127 14 9 0,000 0,0358805 0,08041841 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,0358805 0,0803447 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,0358805 0,08027112 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,0358805 0,08019768 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,0358805 0,08012437 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,0358805 0,0800512 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,0358805 0,07997816 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,0358805 0,07990525 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,0358805 0,07983248 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0358805 0,07975984 ! purine base metabolic process GO:0006144 25 9 0,000 0,0358805 0,07968733 ! pigment granule transport GO:0051904 17 9 0,000 0,0358805 0,07961495 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,0358805 0,07954271 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,0358805 0,07947059 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,0358805 0,07939861 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,0358805 0,07932675 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,0358805 0,07925503 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,0358805 0,07918344 ! mitochondrion localization GO:0051646 18 9 0,000 0,0358805 0,07911197 ! regulation of caspase activity GO:0043281 136 74 1,000 0,03641222 0,08021195 ! respiratory system development GO:0060541 175 74 1,000 0,03641222 0,08013968 ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,03731247 0,08204713 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,03822123 0,08396984 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,03913842 0,08590761 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,03913842 0,08583049 ! regulation of vesicle-mediated transport GO:0060627 136 77 1,000 0,03913842 0,08575351 ! regulation of developmental growth GO:0048638 16 10 0,000 0,03978744 0,08709742 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,03978744 0,08701945 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03978744 0,08694161 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,03978744 0,08686392 ! associative learning GO:0008306 21 10 0,000 0,03978744 0,08678636 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03978744 0,08670894 ! phosphate transport GO:0006817 24 10 0,000 0,03978744 0,08663166 ! cell volume homeostasis GO:0006884 17 10 0,000 0,03978744 0,08655452 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,03978744 0,08647751 ! CTP metabolic process GO:0046036 11 10 0,000 0,03978744 0,08640064 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,03978744 0,08632391 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,03978744 0,08624732 ! GTP metabolic process GO:0046039 11 10 0,000 0,03978744 0,08617085 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,03978744 0,08609453 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,03978744 0,08601834 ! social behavior GO:0035176 29 10 0,000 0,03978744 0,08594228 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,03978744 0,08586636 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,03978744 0,08579058 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,03978744 0,08571492 ! androgen metabolic process GO:0008209 17 10 0,000 0,03978744 0,0856394 ! phospholipid efflux GO:0033700 19 10 0,000 0,03978744 0,08556402 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,03978744 0,08548876 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,03978744 0,08541364 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,03978744 0,08533865 ! lung alveolus development GO:0048286 26 10 0,000 0,03978744 0,08526379 ! pathogenesis GO:0009405 17 10 0,000 0,03978744 0,08518907 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03978744 0,08511447 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,03978744 0,08504 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,03978744 0,08496567 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,03978744 0,08489146 ! endoderm development GO:0007492 18 10 0,000 0,03978744 0,08481739 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,03978744 0,08474344 ! arginine catabolic process GO:0006527 17 10 0,000 0,03978744 0,08466962 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03978744 0,08459593 ! proline metabolic process GO:0006560 13 10 0,000 0,03978744 0,08452237 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03978744 0,08444893 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,03978744 0,08437563 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,03978744 0,08430245 ! V(D)J recombination GO:0033151 34 10 0,000 0,03978744 0,0842294 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,03978744 0,08415647 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,03978744 0,08408367 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,03978744 0,084011 ! B cell proliferation GO:0042100 19 10 0,000 0,03978744 0,08393845 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,03978744 0,08386603 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,03978744 0,08379373 ! multicellular organism growth GO:0035264 19 10 0,000 0,03978744 0,08372155 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,03978744 0,0836495 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,03978744 0,08357758 ! ruffle organization GO:0031529 17 10 0,000 0,03978744 0,08350578 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,03978744 0,0834341 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03978744 0,08336254 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,03978744 0,08329111 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,03978744 0,0832198 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,03978744 0,08314861 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,03978744 0,08307754 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,03978744 0,0830066 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03978744 0,08293577 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03978744 0,08286507 ! protein heterooligomerization GO:0051291 17 10 0,000 0,03978744 0,08279448 ! brain morphogenesis GO:0048854 23 10 0,000 0,03978744 0,08272402 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,03978744 0,08265368 ! segment specification GO:0007379 15 10 0,000 0,03978744 0,08258345 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,03978744 0,08251335 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,03978744 0,08244336 ! blastoderm segmentation GO:0007350 19 10 0,000 0,03978744 0,08237349 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,03978744 0,08230375 ! response to dsRNA GO:0043331 23 10 0,000 0,03978744 0,08223412 ! DNA ligation GO:0006266 18 10 0,000 0,03978744 0,0821646 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,03978744 0,08209521 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03978744 0,08202593 ! melanosome localization GO:0032400 16 10 0,000 0,03978744 0,08195677 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,03978744 0,08188772 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,03978744 0,08181879 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03978744 0,08174998 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,03978744 0,08168128 ! induction of an organ GO:0001759 17 10 0,000 0,03978744 0,0816127 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,03978744 0,08154423 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,03978744 0,08147588 ! protein sumoylation GO:0016925 17 10 0,000 0,03978744 0,08140764 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,03978744 0,08133952 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03978744 0,08127151 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03978744 0,08120361 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03978744 0,08113583 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,03978744 0,08106816 ! salivary gland development GO:0007431 28 10 0,000 0,03978744 0,0810006 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,03978744 0,08093316 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,03978744 0,08086583 ! midbrain development GO:0030901 14 10 0,000 0,03978744 0,08079861 ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,03978744 0,0807315 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,03978744 0,0806645 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,03978744 0,08059762 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,03978744 0,08053084 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,03978744 0,08046418 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03978744 0,08039762 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,03978744 0,08033118 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,03978744 0,08026484 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,03978744 0,08019862 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03978744 0,0801325 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,03978744 0,08006649 ! cerebellar cortex development GO:0021695 16 10 0,000 0,03978744 0,0800006 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,03978744 0,07993481 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,03978744 0,07986912 ! response to nicotine GO:0035094 20 10 0,000 0,03978744 0,07980355 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,03978744 0,07973808 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03978744 0,07967272 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,04006396 0,08016074 ! blood coagulation GO:0007596 151 79 1,000 0,04099777 0,08196199 GO:0050817|coagulation, ! regulation of synaptic transmission GO:0050804 159 79 1,000 0,04099777 0,08189497 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,04193976 0,0837082 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,04193976 0,08363987 ! muscle cell differentiation GO:0042692 178 81 1,000 0,04288986 0,08546486 ! response to hypoxia GO:0001666 178 81 1,000 0,04288986 0,08539521 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,04288986 0,08532567 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 1,000 0,04288986 0,08525624 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,04367866 0,08675364 ! respiratory burst GO:0045730 17 11 0,000 0,04367866 0,08668316 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,04367866 0,0866128 ! neuron fate specification GO:0048665 18 11 0,000 0,04367866 0,08654256 ! telencephalon cell migration GO:0022029 23 11 0,000 0,04367866 0,08647243 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,04367866 0,08640241 ! thyroid gland development GO:0030878 26 11 0,000 0,04367866 0,0863325 ! synapsis GO:0007129 14 11 0,000 0,04367866 0,08626271 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,04367866 0,08619303 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,04367866 0,08612347 ! response to pain GO:0048265 27 11 0,000 0,04367866 0,08605401 ! blood vessel remodeling GO:0001974 30 11 0,000 0,04367866 0,08598467 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,04367866 0,08591544 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,04367866 0,08584632 ! bone resorption GO:0045453 16 11 0,000 0,04367866 0,08577731 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,04367866 0,08570841 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,04367866 0,08563963 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04367866 0,08557095 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04367866 0,08550238 ! melanocyte differentiation GO:0030318 20 11 0,000 0,04367866 0,08543393 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,04367866 0,08536558 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,04367866 0,08529734 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,04367866 0,08522921 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,04367866 0,08516119 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,04367866 0,08509328 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,04367866 0,08502548 ! UV protection GO:0009650 20 11 0,000 0,04367866 0,08495778 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,04367866 0,08489019 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04367866 0,08482271 ! macroautophagy GO:0016236 19 11 0,000 0,04367866 0,08475534 ! behavioral fear response GO:0001662 27 11 0,000 0,04367866 0,08468807 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,04367866 0,08462092 ! negative regulation of ossification GO:0030279 27 11 0,000 0,04367866 0,08455386 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,04367866 0,08448692 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,04367866 0,08442007 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,04367866 0,08435334 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,04367866 0,08428671 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,04367866 0,08422018 ! regulation of organ growth GO:0046620 14 11 0,000 0,04367866 0,08415377 ! pigment granule localization GO:0051875 20 11 0,000 0,04367866 0,08408745 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,04367866 0,08402124 ! vasoconstriction GO:0042310 20 11 0,000 0,04367866 0,08395513 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,04367866 0,08388913 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04367866 0,08382323 ! embryonic axis specification GO:0000578 19 11 0,000 0,04367866 0,08375744 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,04367866 0,08369174 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04367866 0,08362616 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,04367866 0,08356067 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,04367866 0,08349529 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04367866 0,08343 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,04367866 0,08336482 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,04367866 0,08329975 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,04367866 0,08323477 ! prophase GO:0051324 17 11 0,000 0,04367866 0,08316989 ! nucleosome positioning GO:0016584 15 11 0,000 0,04367866 0,08310512 ! regulation of isotype switching GO:0045191 24 11 0,000 0,04367866 0,08304045 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,04367866 0,08297587 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,04367866 0,0829114 ! apical protein localization GO:0045176 18 11 0,000 0,04367866 0,08284703 ! acid secretion GO:0046717 20 11 0,000 0,04367866 0,08278276 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04367866 0,08271858 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,04367866 0,08265451 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,04367866 0,08259054 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,04367866 0,08252666 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,04367866 0,08246289 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,04367866 0,08239921 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,04367866 0,08233563 ! cholesterol efflux GO:0033344 21 11 0,000 0,04367866 0,08227215 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04367866 0,08220876 ! oocyte development GO:0048599 20 11 0,000 0,04367866 0,08214548 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,04367866 0,08208229 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,04367866 0,0820192 ! embryonic gut development GO:0048566 19 11 0,000 0,04367866 0,0819562 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,04367866 0,0818933 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,04367866 0,0818305 ! activation of innate immune response GO:0002218 16 11 0,000 0,04367866 0,0817678 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,04367866 0,08170519 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,04367866 0,08164267 ! lysogeny GO:0030069 22 11 0,000 0,04367866 0,08158026 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04367866 0,08151793 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,04367866 0,08145571 ! sequestering of metal ion GO:0051238 15 11 0,000 0,04367866 0,08139357 ! regulation of embryonic development GO:0045995 35 11 0,000 0,04367866 0,08133154 ! nucleus localization GO:0051647 22 11 0,000 0,04367866 0,08126959 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,04384798 0,08152253 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,04384798 0,08146054 ! response to oxygen levels GO:0070482 183 83 1,000 0,04481404 0,08319203 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,04481404 0,08312886 GO:0045937|positive regulation of phosphate metabolic process, ! digestion GO:0007586 130 84 1,000 0,04578797 0,08487103 ! hemostasis GO:0007599 165 85 1,000 0,04676969 0,08662498 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 0,04676969 0,08655936 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,04676969 0,08649383 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,04755422 0,08787819 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,04755422 0,08781177 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,04755422 0,08774544 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,04755422 0,08767922 ! virus-host interaction GO:0019048 30 12 0,000 0,04755422 0,0876131 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,04755422 0,08754707 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,04755422 0,08748115 ! protein complex disassembly GO:0043241 28 12 0,000 0,04755422 0,08741533 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04755422 0,0873496 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,04755422 0,08728397 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,04755422 0,08721844 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,04755422 0,08715301 ! T cell proliferation GO:0042098 32 12 0,000 0,04755422 0,08708768 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,04755422 0,08702245 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,04755422 0,08695731 ! ventral spinal cord development GO:0021517 25 12 0,000 0,04755422 0,08689227 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,04755422 0,08682733 ! drug transport GO:0015893 16 12 0,000 0,04755422 0,08676248 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,04755422 0,08669774 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,04755422 0,08663309 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,04755422 0,08656853 ! polyamine metabolic process GO:0006595 18 12 0,000 0,04755422 0,08650407 ! mitotic spindle organization GO:0007052 23 12 0,000 0,04755422 0,08643971 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,04755422 0,08637544 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,04755422 0,08631127 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,04755422 0,08624719 ! lipid digestion GO:0044241 21 12 0,000 0,04755422 0,08618321 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,04755422 0,08611932 ! entry into host cell GO:0030260 34 12 0,000 0,04755422 0,08605553 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04755422 0,08599183 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,04755422 0,08592823 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,04755422 0,08586472 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04755422 0,08580131 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,04755422 0,08573798 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,04755422 0,08567475 ! snRNA metabolic process GO:0016073 30 12 0,000 0,04755422 0,08561162 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,04755422 0,08554858 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,04755422 0,08548563 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04755422 0,08542277 ! cranial nerve development GO:0021545 23 12 0,000 0,04755422 0,08536001 ! fucose catabolic process GO:0019317 25 12 0,000 0,04755422 0,08529733 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,04755422 0,08523475 ! histone acetylation GO:0016573 27 12 0,000 0,04755422 0,08517226 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,04755422 0,08510987 ! autonomic nervous system development GO:0048483 24 12 0,000 0,04755422 0,08504756 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,04755422 0,08498535 ! zymogen activation GO:0031638 18 12 0,000 0,04755422 0,08492322 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,04755422 0,08486119 ! T cell homeostasis GO:0043029 28 12 0,000 0,04755422 0,08479925 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,04755422 0,08473739 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,04755422 0,08467563 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,04755422 0,08461396 ! oocyte differentiation GO:0009994 21 12 0,000 0,04755422 0,08455238 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,04755422 0,08449089 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,04755422 0,08442948 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,04755422 0,08436817 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,04755422 0,08430694 ! defense response to fungus GO:0050832 15 12 0,000 0,04755422 0,08424581 ! developmental induction GO:0031128 22 12 0,000 0,04755422 0,08418476 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,04755422 0,0841238 ! lamellipodium assembly GO:0030032 24 12 0,000 0,04755422 0,08406293 ! response to cold GO:0009409 17 12 0,000 0,04755422 0,08400215 ! establishment of cell polarity GO:0030010 21 12 0,000 0,04755422 0,08394145 ! regulation of synapse organization GO:0050807 18 12 0,000 0,04755422 0,08388084 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,04775912 0,08418147 GO:0002696|positive regulation of leukocyte activation, ! regulation of protein transport GO:0051223 165 87 1,000 0,04875617 0,08587695 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 1,000 0,04976079 0,08758329 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,04976079 0,08752023 ! tube morphogenesis GO:0035239 194 89 1,000 0,05077288 0,08923607 ! regulation of neurological system process GO:0031644 175 89 1,000 0,05077288 0,08917192 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,05141419 0,09023337 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05141419 0,0901686 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,05141419 0,09010391 ! regulation of chemokine production GO:0032642 18 13 0,000 0,05141419 0,09003932 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05141419 0,08997483 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,05141419 0,08991042 ! peroxisomal transport GO:0043574 28 13 0,000 0,05141419 0,08984611 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,05141419 0,08978188 ! cartilage condensation GO:0001502 22 13 0,000 0,05141419 0,08971775 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,05141419 0,08965372 ! organelle fusion GO:0048284 36 13 0,000 0,05141419 0,08958977 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,05141419 0,08952591 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,05141419 0,08946215 ! endocrine pancreas development GO:0031018 25 13 0,000 0,05141419 0,08939847 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,05141419 0,08933489 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,05141419 0,0892714 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,05141419 0,08920799 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05141419 0,08914468 ! methionine metabolic process GO:0006555 31 13 0,000 0,05141419 0,08908146 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,05141419 0,08901832 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,05141419 0,08895528 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,05141419 0,08889233 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,05141419 0,08882946 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,05141419 0,08876668 ! cytokine metabolic process GO:0042107 24 13 0,000 0,05141419 0,08870399 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,05141419 0,08864139 ! exocrine system development GO:0035272 34 13 0,000 0,05141419 0,08857888 ! asymmetric protein localization GO:0008105 24 13 0,000 0,05141419 0,08851646 ! monoamine transport GO:0015844 21 13 0,000 0,05141419 0,08845412 ! L-glutamate transport GO:0015813 30 13 0,000 0,05141419 0,08839188 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,05141419 0,08832972 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,05141419 0,08826764 ! protein homotetramerization GO:0051289 24 13 0,000 0,05141419 0,08820566 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,05141419 0,08814376 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,05141419 0,08808195 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,05141419 0,08802022 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,05141419 0,08795858 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,05141419 0,08789703 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05141419 0,08783556 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,05141419 0,08777418 ! chromatin silencing GO:0006342 29 13 0,000 0,05141419 0,08771289 ! gland morphogenesis GO:0022612 31 13 0,000 0,05141419 0,08765168 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,05141419 0,08759056 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05141419 0,08752952 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,05141419 0,08746856 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,05141419 0,08740769 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,05141419 0,08734691 ! spleen development GO:0048536 24 13 0,000 0,05141419 0,08728621 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,05141419 0,08722559 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,05141419 0,08716506 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,05141419 0,08710462 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,05141419 0,08704425 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,05141419 0,08698397 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05141419 0,08692378 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,05141419 0,08686366 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,05141419 0,08680363 ! insulin secretion GO:0030073 24 13 0,000 0,05141419 0,08674369 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,05141419 0,08668382 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,05141419 0,08662404 ! acrosome reaction GO:0007340 19 13 0,000 0,05141419 0,08656434 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,05141419 0,08650472 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,05141419 0,08644519 ! positive regulation of protein modification process GO:0031401 156 90 1,000 0,05179237 0,08702115 ! ossification GO:0001503 205 91 1,000 0,05281918 0,08868541 ! bone development GO:0060348 206 92 1,000 0,05385325 0,09035954 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,05385325 0,09029752 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,05489449 0,09198028 GO:0010498|proteasomal protein catabolic process, ! rRNA transcription GO:0009303 28 14 0,000 0,05525861 0,09252693 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,05525861 0,09246356 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,05525861 0,09240027 ! water transport GO:0006833 21 14 0,000 0,05525861 0,09233707 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,05525861 0,09227395 ! non-recombinational repair GO:0000726 29 14 0,000 0,05525861 0,09221092 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,05525861 0,09214798 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,05525861 0,09208512 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,05525861 0,09202235 ! RNA polyadenylation GO:0043631 32 14 0,000 0,05525861 0,09195967 ! lipid localization GO:0010876 32 14 0,000 0,05525861 0,09189707 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,05525861 0,09183455 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,05525861 0,09177212 ! regulated secretory pathway GO:0045055 24 14 0,000 0,05525861 0,09170978 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,05525861 0,09164752 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,05525861 0,09158534 ! arginine metabolic process GO:0006525 21 14 0,000 0,05525861 0,09152325 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,05525861 0,09146124 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,05525861 0,09139932 ! regulation of heart rate GO:0002027 25 14 0,000 0,05525861 0,09133748 ! fear response GO:0042596 34 14 0,000 0,05525861 0,09127572 ! organic alcohol transport GO:0015850 29 14 0,000 0,05525861 0,09121405 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,05525861 0,09115246 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,05525861 0,09109095 ! neutral amino acid transport GO:0015804 28 14 0,000 0,05525861 0,09102953 ! bone mineralization GO:0030282 18 14 0,000 0,05525861 0,09096819 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,05525861 0,09090693 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,05525861 0,09084576 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,05525861 0,09078466 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,05525861 0,09072365 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,05525861 0,09066272 ! regulation of cellular pH GO:0030641 27 14 0,000 0,05525861 0,09060187 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,05525861 0,09054111 ! ribosome assembly GO:0042255 18 14 0,000 0,05525861 0,09048042 ! cerebellum development GO:0021549 23 14 0,000 0,05525861 0,09041982 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,05525861 0,0903593 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,05525861 0,09029886 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,05525861 0,0902385 ! response to gamma radiation GO:0010332 30 14 0,000 0,05525861 0,09017822 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,05525861 0,09011802 ! NADP metabolic process GO:0006739 24 14 0,000 0,05525861 0,0900579 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,05525861 0,08999786 ! oxygen transport GO:0015671 22 14 0,000 0,05525861 0,0899379 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05525861 0,08987802 ! male genitalia development GO:0030539 26 14 0,000 0,05525861 0,08981823 ! regulation of RNA stability GO:0043487 33 14 0,000 0,05525861 0,08975851 ! regulation of axon extension GO:0030516 43 14 0,000 0,05525861 0,08969887 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,05525861 0,0896393 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,05525861 0,08957982 ! regulation of membrane potential GO:0042391 179 94 1,000 0,05594284 0,09062888 ! regulation of T cell activation GO:0050863 175 96 1,000 0,05806054 0,09399728 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,05908757 0,09559664 ! lactation GO:0007595 30 15 0,000 0,05908757 0,09553337 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,05908757 0,09547019 ! reproductive cellular process GO:0048610 22 15 0,000 0,05908757 0,09540709 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,05908757 0,09534407 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,05908757 0,09528114 ! superoxide anion generation GO:0042554 22 15 0,000 0,05908757 0,09521829 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,05908757 0,09515552 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,05908757 0,09509284 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,05908757 0,09503024 ! copper ion transport GO:0006825 22 15 0,000 0,05908757 0,09496772 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,05908757 0,09490528 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,05908757 0,09484292 ! sulfate transport GO:0008272 27 15 0,000 0,05908757 0,09478065 ! response to cAMP GO:0051591 25 15 0,000 0,05908757 0,09471846 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,05908757 0,09465635 ! response to hexose stimulus GO:0009746 25 15 0,000 0,05908757 0,09459432 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,05908757 0,09453237 ! vesicle coating GO:0006901 38 15 0,000 0,05908757 0,0944705 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,05908757 0,09440872 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,05908757 0,09434701 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,05908757 0,09428539 ! regulation of exocytosis GO:0017157 26 15 0,000 0,05908757 0,09422384 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,05908757 0,09416238 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,05908757 0,094101 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,05908757 0,09403969 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,05908757 0,09397847 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,05908757 0,09391733 ! regulation of vasodilation GO:0042312 27 15 0,000 0,05908757 0,09385626 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,05908757 0,09379528 ! histone deacetylation GO:0016575 24 15 0,000 0,05908757 0,09373437 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,05908757 0,09367354 ! water homeostasis GO:0030104 28 15 0,000 0,05908757 0,09361279 ! cofactor transport GO:0051181 30 15 0,000 0,05908757 0,09355213 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,05908757 0,09349153 ! muscle maintenance GO:0046716 26 15 0,000 0,05908757 0,09343102 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,05908757 0,09337059 ! intestinal absorption GO:0050892 31 15 0,000 0,05908757 0,09331023 ! dopamine metabolic process GO:0042417 35 15 0,000 0,05908757 0,09324995 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,05908757 0,09318975 ! heme biosynthetic process GO:0006783 33 15 0,000 0,05908757 0,09312963 ! cell killing GO:0001906 32 15 0,000 0,05908757 0,09306959 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,05908757 0,09300962 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,05908757 0,09294973 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,05908757 0,09288992 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,05908757 0,09283018 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,05908757 0,09277052 ! actin filament polymerization GO:0030041 27 15 0,000 0,05908757 0,09271094 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,05908757 0,09265143 ! transcription initiation GO:0006352 171 97 1,000 0,05912975 0,0926581 ! regulation of protein localization GO:0032880 188 97 1,000 0,05912975 0,09259871 ! forebrain development GO:0030900 210 98 1,000 0,06020577 0,09422338 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,06237795 0,0975604 GO:0060538|skeletal muscle organ development, ! hormone metabolic process GO:0042445 171 100 1,000 0,06237795 0,09749798 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,06290111 0,09825282 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,06290111 0,09819004 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,06290111 0,09812734 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,06290111 0,09806472 ! bone remodeling GO:0046849 28 16 0,000 0,06290111 0,09800218 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,06290111 0,09793972 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,06290111 0,09787733 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,06290111 0,09781503 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,06290111 0,09775281 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,06290111 0,09769066 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,06290111 0,0976286 ! startle response GO:0001964 28 16 0,000 0,06290111 0,09756661 ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,06290111 0,09750471 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,06290111 0,09744288 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,06290111 0,09738113 ! protein polyubiquitination GO:0000209 41 16 0,000 0,06290111 0,09731945 ! glutamate metabolic process GO:0006536 25 16 0,000 0,06290111 0,09725786 ! pituitary gland development GO:0021983 30 16 0,000 0,06290111 0,09719634 ! response to osmotic stress GO:0006970 27 16 0,000 0,06290111 0,0971349 ! lysosomal transport GO:0007041 31 16 0,000 0,06290111 0,09707354 ! fructose metabolic process GO:0006000 25 16 0,000 0,06290111 0,09701226 ! L-amino acid transport GO:0015807 33 16 0,000 0,06290111 0,09695105 ! stem cell development GO:0048864 46 16 0,000 0,06290111 0,09688992 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06290111 0,09682887 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06290111 0,09676789 ! intermediate filament-based process GO:0045103 36 16 0,000 0,06290111 0,096707 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,06290111 0,09664617 ! negative regulation of immune response GO:0050777 38 16 0,000 0,06290111 0,09658543 ! axon cargo transport GO:0008088 46 16 0,000 0,06290111 0,09652476 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,06290111 0,09646417 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,06290111 0,09640365 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,06290111 0,09634321 ! DNA replication initiation GO:0006270 28 16 0,000 0,06290111 0,09628284 ! neuron recognition GO:0008038 40 16 0,000 0,06290111 0,09622255 ! mRNA splice site selection GO:0006376 44 16 0,000 0,06290111 0,09616234 ! tissue regeneration GO:0042246 27 16 0,000 0,06290111 0,0961022 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,06290111 0,09604213 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,06290111 0,09598215 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,06290111 0,09592223 ! biomineral formation GO:0031214 22 16 0,000 0,06290111 0,09586239 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,06290111 0,09580263 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,06290111 0,09574294 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,06290111 0,09568332 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06290111 0,09562378 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,06290111 0,09556431 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,06290111 0,09550492 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,06290111 0,0954456 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,06290111 0,09538635 ! peptide hormone processing GO:0016486 27 16 0,000 0,06290111 0,09532718 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,06669931 0,10102071 ! metencephalon development GO:0022037 32 17 0,000 0,06669931 0,10095812 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,06669931 0,10089561 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,06669931 0,10083317 ! signal complex assembly GO:0007172 47 17 0,000 0,06669931 0,10077081 ! filopodium assembly GO:0046847 42 17 0,000 0,06669931 0,10070853 ! endothelial cell migration GO:0043542 31 17 0,000 0,06669931 0,10064633 ! gene silencing by RNA GO:0031047 38 17 0,000 0,06669931 0,1005842 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,06669931 0,10052215 ! glial cell development GO:0021782 28 17 0,000 0,06669931 0,10046018 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,06669931 0,10039828 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,06669931 0,10033646 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,06669931 0,10027471 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,06669931 0,10021304 ! myoblast differentiation GO:0045445 50 17 0,000 0,06669931 0,10015145 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,06669931 0,10008993 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,06669931 0,10002849 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,06669931 0,09996712 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,06669931 0,09990583 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,06669931 0,09984461 ! NAD metabolic process GO:0019674 33 17 0,000 0,06669931 0,09978347 ! membrane budding GO:0006900 42 17 0,000 0,06669931 0,0997224 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,06669931 0,09966141 ! regulation of protein binding GO:0043393 33 17 0,000 0,06669931 0,09960049 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,06669931 0,09953965 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,06669931 0,09947888 ! genitalia development GO:0048806 32 17 0,000 0,06669931 0,09941818 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,06669931 0,09935756 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,06669931 0,09929702 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,06669931 0,09923654 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,06669931 0,09917614 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,06669931 0,09911582 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,06669931 0,09905556 ! steroid catabolic process GO:0006706 34 17 0,000 0,06669931 0,09899539 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,06669931 0,09893528 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,06669931 0,09887525 ! gas transport GO:0015669 26 17 0,000 0,06669931 0,09881528 ! organic cation transport GO:0015695 32 17 0,000 0,06669931 0,0987554 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,06669931 0,09869558 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,06669931 0,09863584 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,06669931 0,09857617 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,07048221 0,10410402 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,07048221 0,10404111 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,07048221 0,10397829 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,07048221 0,10391554 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,07048221 0,10385286 ! adult walking behavior GO:0007628 36 18 0,000 0,07048221 0,10379026 ! patterning of blood vessels GO:0001569 43 18 0,000 0,07048221 0,10372774 ! heart looping GO:0001947 34 18 0,000 0,07048221 0,10366529 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,07048221 0,10360291 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,07048221 0,10354062 ! centrosome cycle GO:0007098 26 18 0,000 0,07048221 0,10347839 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,07048221 0,10341624 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,07048221 0,10335417 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,07048221 0,10329217 ! glycine metabolic process GO:0006544 30 18 0,000 0,07048221 0,10323024 ! glutamine metabolic process GO:0006541 29 18 0,000 0,07048221 0,10316839 ! response to retinoic acid GO:0032526 31 18 0,000 0,07048221 0,10310661 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,07048221 0,10304491 ! DNA integration GO:0015074 32 18 0,000 0,07048221 0,10298328 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,07048221 0,10292172 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,07048221 0,10286024 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,07048221 0,10279883 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,07048221 0,1027375 ! neural crest cell migration GO:0001755 41 18 0,000 0,07048221 0,10267623 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,07048221 0,10261504 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,07048221 0,10255393 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,07048221 0,10249288 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,07048221 0,10243191 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,07048221 0,10237101 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,07048221 0,10231019 ! detection of bacterium GO:0016045 22 18 0,000 0,07048221 0,10224943 ! nerve development GO:0021675 34 18 0,000 0,07048221 0,10218875 ! defense response to virus GO:0051607 43 18 0,000 0,07048221 0,10212814 ! microspike assembly GO:0030035 46 18 0,000 0,07048221 0,1020676 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,07048221 0,10200713 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,07424989 0,10739638 ! positive regulation of translation GO:0045727 31 19 0,000 0,07424989 0,10733283 ! negative regulation of defense response GO:0031348 27 19 0,000 0,07424989 0,10726936 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,07424989 0,10720596 ! neuron maturation GO:0042551 46 19 0,000 0,07424989 0,10714264 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,07424989 0,10707939 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,07424989 0,10701621 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,07424989 0,10695311 ! inositol metabolic process GO:0006020 33 19 0,000 0,07424989 0,10689009 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,07424989 0,10682714 ! memory GO:0007613 34 19 0,000 0,07424989 0,10676426 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,07424989 0,10670146 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,07424989 0,10663873 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,07424989 0,10657608 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,07424989 0,1065135 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,07424989 0,10645099 ! cerebral cortex development GO:0021987 40 19 0,000 0,07424989 0,10638855 ! pigmentation during development GO:0048066 42 19 0,000 0,07424989 0,10632619 ! response to vitamin A GO:0033189 32 19 0,000 0,07424989 0,1062639 ! heme metabolic process GO:0042168 40 19 0,000 0,07424989 0,10620169 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,07424989 0,10613955 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,07424989 0,10607748 ! response to fungus GO:0009620 26 19 0,000 0,07424989 0,10601548 ! peptide cross-linking GO:0018149 39 19 0,000 0,07424989 0,10595355 ! protein export from nucleus GO:0006611 40 19 0,000 0,07424989 0,1058917 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,07424989 0,10582992 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,07424989 0,10576821 ! visual learning GO:0008542 38 19 0,000 0,07424989 0,10570658 ! cellular pigmentation GO:0033059 37 19 0,000 0,07424989 0,10564501 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,07424989 0,10558352 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,07424989 0,1055221 ! vitamin transport GO:0051180 31 19 0,000 0,07424989 0,10546075 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,07424989 0,10539947 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,07424989 0,10533826 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,07424989 0,10527712 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,07424989 0,10521606 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,07424989 0,10515506 ! cilium assembly GO:0042384 38 19 0,000 0,07424989 0,10509414 ! peptide hormone secretion GO:0030072 32 19 0,000 0,07424989 0,10503328 ! protein secretion GO:0009306 45 20 0,000 0,0780024 0,1102777 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,0780024 0,11021392 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,0780024 0,11015021 ! positive regulation of ossification GO:0045778 50 20 0,000 0,0780024 0,11008658 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,0780024 0,11002302 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,0780024 0,10995953 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,0780024 0,10989612 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,0780024 0,10983278 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,0780024 0,10976951 ! response to vitamin GO:0033273 36 20 0,000 0,0780024 0,10970632 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,0780024 0,10964319 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,0780024 0,10958014 ! bile acid metabolic process GO:0008206 34 20 0,000 0,0780024 0,10951717 ! response to alkaloid GO:0043279 38 20 0,000 0,0780024 0,10945426 ! retinoid metabolic process GO:0001523 34 20 0,000 0,0780024 0,10939143 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,0780024 0,10932867 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,0780024 0,10926598 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,0780024 0,10920336 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,0780024 0,10914082 GO:0030968|endoplasmic reticulum unfolded protein response, ! body fluid secretion GO:0007589 33 20 0,000 0,0780024 0,10907835 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,0780024 0,10901594 ! peptide secretion GO:0002790 38 20 0,000 0,0780024 0,10895361 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,0780024 0,10889136 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,0780024 0,10882917 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,0780024 0,10876705 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,0780024 0,108705 ! cell-cell junction organization GO:0045216 43 20 0,000 0,0780024 0,10864303 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,0780024 0,10858112 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,0780024 0,10851929 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,0780024 0,10845753 ! regulation of glucose import GO:0046324 30 20 0,000 0,0780024 0,10839583 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,0780024 0,10833421 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,0780024 0,10827265 ! negative regulation of translation GO:0017148 32 20 0,000 0,0780024 0,10821117 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,0780024 0,10814976 ! regulation of cell killing GO:0031341 46 21 0,000 0,08173981 0,11326736 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,08173981 0,11320315 ! hormone secretion GO:0046879 39 21 0,000 0,08173981 0,11313901 ! cAMP metabolic process GO:0046058 41 21 0,000 0,08173981 0,11307495 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,08173981 0,11301095 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,08173981 0,11294703 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,08173981 0,11288319 ! smooth muscle contraction GO:0006939 48 21 0,000 0,08173981 0,11281941 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,08173981 0,11275571 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,08173981 0,11269208 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,08173981 0,11262852 ! plasma membrane fusion GO:0045026 33 21 0,000 0,08173981 0,11256503 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,08173981 0,11250161 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,08173981 0,11243826 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,08173981 0,11237499 ! sensory perception of pain GO:0019233 33 21 0,000 0,08173981 0,11231179 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,08173981 0,11224866 ! diencephalon development GO:0021536 36 21 0,000 0,08173981 0,11218559 ! collagen fibril organization GO:0030199 62 21 0,000 0,08173981 0,1121226 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,08173981 0,11205968 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,08173981 0,11199684 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,08173981 0,11193406 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,08173981 0,11187135 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,08173981 0,11180871 ! collagen catabolic process GO:0030574 29 21 0,000 0,08173981 0,11174614 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,08173981 0,11168365 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,08173981 0,11162122 ! sperm-egg recognition GO:0035036 23 21 0,000 0,08173981 0,11155886 ! actin filament-based movement GO:0030048 47 21 0,000 0,08173981 0,11149657 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,08173981 0,11143435 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,08546217 0,116444 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,08546217 0,11637909 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,08546217 0,11631426 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,08546217 0,11624949 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,08546217 0,1161848 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,08546217 0,11612018 ! microtubule-based transport GO:0010970 59 22 0,000 0,08546217 0,11605564 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,08546217 0,11599116 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,08546217 0,11592676 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,08546217 0,11586242 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,08546217 0,11579816 ! vacuolar transport GO:0007034 41 22 0,000 0,08546217 0,11573397 ! central nervous system neuron development GO:0021954 47 22 0,000 0,08546217 0,11566985 ! fucose metabolic process GO:0006004 44 22 0,000 0,08546217 0,11560581 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,08546217 0,11554183 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,08546217 0,11547792 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,08546217 0,11541409 ! ureteric bud development GO:0001657 50 22 0,000 0,08546217 0,11535032 ! cell aging GO:0007569 48 22 0,000 0,08546217 0,11528663 ! stem cell differentiation GO:0048863 57 22 0,000 0,08546217 0,11522301 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,08546217 0,11515945 ! cytolysis GO:0019835 27 22 0,000 0,08546217 0,11509597 ! renal system process GO:0003014 42 22 0,000 0,08546217 0,11503256 ! vasodilation GO:0042311 40 22 0,000 0,08546217 0,11496921 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,08546217 0,11490594 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,08546217 0,11484273 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1 phase GO:0051318 44 22 0,000 0,08546217 0,1147796 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,08546217 0,11471653 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,08546217 0,11465354 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,08546217 0,11459061 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,08546217 0,11452775 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,08546217 0,11446496 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,08546217 0,11440224 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,08546217 0,11433959 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,08546217 0,114277 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,08546217 0,11421449 ! gut development GO:0048565 44 22 0,000 0,08546217 0,11415204 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,08546217 0,11408967 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,08546217 0,11402736 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,08546217 0,11396511 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,08916955 0,11884409 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,08916955 0,11877929 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,08916955 0,11871456 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,08916955 0,1186499 ! gluconeogenesis GO:0006094 38 23 0,000 0,08916955 0,11858531 ! glycerol metabolic process GO:0006071 40 23 0,000 0,08916955 0,11852079 ! viral genome replication GO:0019079 44 23 0,000 0,08916955 0,11845634 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,08916955 0,11839196 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,08916955 0,11832765 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,08916955 0,11826341 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,08916955 0,11819925 ! regeneration GO:0031099 42 23 0,000 0,08916955 0,11813515 ! axis specification GO:0009798 43 23 0,000 0,08916955 0,11807112 ! visual behavior GO:0007632 46 23 0,000 0,08916955 0,11800716 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,08916955 0,11794326 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,08916955 0,11787944 ! response to ethanol GO:0045471 47 23 0,000 0,08916955 0,11781569 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,08916955 0,11775201 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,08916955 0,11768839 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,08916955 0,11762484 ! peroxisome organization GO:0007031 43 23 0,000 0,08916955 0,11756137 ! lysosome organization GO:0007040 47 23 0,000 0,08916955 0,11749796 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,08916955 0,11743461 ! vesicle targeting GO:0006903 49 23 0,000 0,08916955 0,11737134 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,08916955 0,11730814 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,08916955 0,117245 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,08916955 0,11718193 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,08916955 0,11711893 ! DNA modification GO:0006304 36 23 0,000 0,08916955 0,117056 ! fatty acid transport GO:0015908 47 23 0,000 0,08916955 0,11699313 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,08916955 0,11693033 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,08916955 0,1168676 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,08916955 0,11680494 ! hormone transport GO:0009914 41 23 0,000 0,08916955 0,11674234 ! cell-cell recognition GO:0009988 28 23 0,000 0,08916955 0,11667981 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,08916955 0,11661735 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,08916955 0,11655495 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,08916955 0,11649263 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,092862 0,12125167 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,092862 0,1211869 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,092862 0,12112219 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,092862 0,12105756 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,092862 0,120993 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,092862 0,1209285 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,092862 0,12086408 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,092862 0,12079972 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,092862 0,12073543 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,092862 0,12067121 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,092862 0,12060705 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,092862 0,12054297 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,092862 0,12047895 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,092862 0,12041501 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,092862 0,12035112 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,092862 0,12028731 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,092862 0,12022357 ! regulation of viral reproduction GO:0050792 41 24 0,000 0,092862 0,12015989 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,092862 0,12009628 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,092862 0,12003274 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,092862 0,11996926 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,092862 0,11990585 ! membrane depolarization GO:0051899 45 24 0,000 0,092862 0,11984251 ! oogenesis GO:0048477 44 24 0,000 0,092862 0,11977923 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,092862 0,11971603 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,092862 0,11965289 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,092862 0,11958981 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,092862 0,1195268 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,092862 0,11946386 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,092862 0,11940098 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,092862 0,11933817 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,092862 0,11927543 ! regulation of amine transport GO:0051952 41 24 0,000 0,092862 0,11921275 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,09653959 0,12386881 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,09653959 0,12380379 ! leukocyte adhesion GO:0007159 55 25 0,000 0,09653959 0,12373883 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,09653959 0,12367395 ! phototransduction GO:0007602 37 25 0,000 0,09653959 0,12360913 ! keratinization GO:0031424 37 25 0,000 0,09653959 0,12354438 ! vasculogenesis GO:0001570 49 25 0,000 0,09653959 0,12347969 ! vacuole organization GO:0007033 49 25 0,000 0,09653959 0,12341508 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,09653959 0,12335053 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,09653959 0,12328605 ! receptor metabolic process GO:0043112 53 25 0,000 0,09653959 0,12322164 ! chromosome condensation GO:0030261 48 25 0,000 0,09653959 0,12315729 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,09653959 0,12309301 ! regulation of behavior GO:0050795 48 25 0,000 0,09653959 0,1230288 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,09653959 0,12296466 ! interaction with host GO:0051701 66 25 0,000 0,09653959 0,12290058 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,09653959 0,12283657 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,09653959 0,12277263 ! immunoglobulin production GO:0002377 62 25 0,000 0,09653959 0,12270875 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,09653959 0,12264494 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,09653959 0,12258119 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,09653959 0,12251751 ! liver development GO:0001889 55 25 0,000 0,09653959 0,1224539 ! protein tetramerization GO:0051262 57 25 0,000 0,09653959 0,12239035 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,10020237 0,12696804 ! initiation of viral infection GO:0019059 60 26 0,000 0,10020237 0,12690222 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,10020237 0,12683647 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,10020237 0,12677079 ! molting cycle process GO:0022404 52 26 0,000 0,10020237 0,12670517 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,10020237 0,12663962 ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,10020237 0,12657414 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,10020237 0,12650873 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,10020237 0,12644338 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,10020237 0,1263781 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,10020237 0,12631289 ! digestive system process GO:0022600 49 26 0,000 0,10020237 0,12624775 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,10020237 0,12618267 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,10020237 0,12611766 ! osteoblast differentiation GO:0001649 63 26 0,000 0,10020237 0,12605272 ! neural crest cell development GO:0014032 59 26 0,000 0,10020237 0,12598785 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,10020237 0,12592304 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,10020237 0,1258583 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,10020237 0,12579362 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,10020237 0,12572901 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,10020237 0,12566447 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,10020237 0,12559999 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,10020237 0,12553558 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,10020237 0,12547124 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,10020237 0,12540696 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,10020237 0,12534275 ! telomere organization GO:0032200 46 26 0,000 0,10020237 0,1252786 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,10020237 0,12521452 ! neural tube closure GO:0001843 58 26 0,000 0,10020237 0,1251505 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,10020237 0,12508655 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,10020237 0,12502267 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,10020237 0,12495885 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,1038504 0,12944211 ! embryonic pattern specification GO:0009880 49 27 0,000 0,1038504 0,1293761 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,1038504 0,12931016 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,1038504 0,12924429 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,1038504 0,12917848 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,1038504 0,12911274 ! iron ion transport GO:0006826 65 27 0,000 0,1038504 0,12904707 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,1038504 0,12898146 ! superoxide metabolic process GO:0006801 41 27 0,000 0,1038504 0,12891592 ! tube lumen formation GO:0035148 59 27 0,000 0,1038504 0,12885045 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,1038504 0,12878504 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,1038504 0,1287197 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,1038504 0,12865443 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,1038504 0,12858922 ! response to toxin GO:0009636 49 27 0,000 0,1038504 0,12852408 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,1038504 0,128459 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,1038504 0,12839399 ! leukocyte proliferation GO:0070661 59 27 0,000 0,1038504 0,12832905 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,10748375 0,13275167 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,10748375 0,13268459 ! protein amino acid acylation GO:0043543 59 28 0,000 0,10748375 0,13261757 ! vesicle docking GO:0048278 55 28 0,000 0,10748375 0,13255063 ! circadian rhythm GO:0007623 56 28 0,000 0,10748375 0,13248375 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,10748375 0,13241694 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,10748375 0,1323502 ! sperm motility GO:0030317 37 28 0,000 0,10748375 0,13228352 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,10748375 0,13221692 ! base-excision repair GO:0006284 41 28 0,000 0,10748375 0,13215038 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,10748375 0,1320839 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,10748375 0,13201749 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,10748375 0,13195115 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,10748375 0,13188488 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,10748375 0,13181867 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,10748375 0,13175253 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,10748375 0,13168646 ! glutathione metabolic process GO:0006749 42 28 0,000 0,10748375 0,13162045 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,10748375 0,13155451 ! lipid oxidation GO:0034440 48 28 0,000 0,10748375 0,13148863 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,10748375 0,13142282 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,10748375 0,13135708 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,11110246 0,13571166 ! translational initiation GO:0006413 66 29 0,000 0,11110246 0,13564384 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,11110246 0,13557608 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,11110246 0,1355084 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,11110246 0,13544078 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,11110246 0,13537323 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,11110246 0,13530574 ! primary neural tube formation GO:0014020 61 29 0,000 0,11110246 0,13523833 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,11110246 0,13517098 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,11110246 0,13510369 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,11110246 0,13503648 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,11110246 0,13496933 ! somitogenesis GO:0001756 52 29 0,000 0,11110246 0,13490225 ! synaptogenesis GO:0007416 46 29 0,000 0,11110246 0,13483523 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,11110246 0,13476828 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,11110246 0,1347014 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,11110246 0,13463458 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,11470661 0,13893319 ! phenol metabolic process GO:0018958 56 30 0,000 0,11470661 0,13886435 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,11470661 0,13879557 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,11470661 0,13872686 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,11470661 0,13865821 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,11470661 0,13858964 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,11470661 0,13852113 ! acute-phase response GO:0006953 50 30 0,000 0,11470661 0,13845269 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,11470661 0,13838432 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,11470661 0,13831602 ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,11470661 0,13824778 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,11470661 0,13817961 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,11470661 0,13811151 ! cell fate determination GO:0001709 64 30 0,000 0,11470661 0,13804347 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,11470661 0,1379755 ! phospholipid transport GO:0015914 65 30 0,000 0,11470661 0,1379076 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,11470661 0,13783977 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,11470661 0,137772 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,11470661 0,1377043 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,11470661 0,13763666 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,11470661 0,1375691 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,11470661 0,13750159 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,11829624 0,14173503 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,11829624 0,14166555 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,11829624 0,14159614 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,11829624 0,1415268 ! regulation of innate immune response GO:0045088 57 31 0,000 0,11829624 0,14145753 ! peptide transport GO:0015833 60 31 0,000 0,11829624 0,14138832 ! male gonad development GO:0008584 56 31 0,000 0,11829624 0,14131918 ! iron ion homeostasis GO:0055072 60 31 0,000 0,11829624 0,14125011 ! detection of light stimulus GO:0009583 44 31 0,000 0,11829624 0,14118111 ! natural killer cell activation GO:0030101 50 31 0,000 0,11829624 0,14111217 ! cofactor catabolic process GO:0051187 54 31 0,000 0,11829624 0,1410433 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,11829624 0,1409745 ! eye morphogenesis GO:0048592 65 31 0,000 0,11829624 0,14090577 ! response to heat GO:0009408 54 31 0,000 0,11829624 0,1408371 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,11829624 0,1407685 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,12187142 0,14495223 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,12187142 0,1448817 ! collagen metabolic process GO:0032963 49 32 0,000 0,12187142 0,14481123 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,12187142 0,14474083 ! spindle organization GO:0007051 50 32 0,000 0,12187142 0,1446705 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,12187142 0,14460024 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,12187142 0,14453004 ! metanephros development GO:0001656 81 32 0,000 0,12187142 0,14445992 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,12187142 0,14438986 ! mesoderm formation GO:0001707 73 32 0,000 0,12187142 0,14431987 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,12187142 0,14424995 ! BMP signaling pathway GO:0030509 71 32 0,000 0,12187142 0,14418009 ! hindbrain development GO:0030902 65 32 0,000 0,12187142 0,1441103 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,12187142 0,14404058 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,12187142 0,14397093 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,12187142 0,14390135 ! gene silencing GO:0016458 71 32 0,000 0,12187142 0,14383183 ! regulation of pH GO:0006885 56 33 0,000 0,12543221 0,14796276 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,12543221 0,14789135 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,12543221 0,14782001 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,12543221 0,14774874 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,12543221 0,14767753 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,12543221 0,1476064 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,12543221 0,14753533 ! response to ionizing radiation GO:0010212 74 33 0,000 0,12543221 0,14746433 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,12543221 0,1473934 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,12543221 0,14732254 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,12543221 0,14725174 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,12543221 0,14718102 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,12543221 0,14711036 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,12543221 0,14703977 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,12543221 0,14696925 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,12897865 0,15105218 ! glial cell differentiation GO:0010001 67 34 0,000 0,12897865 0,1509798 ! post-embryonic development GO:0009791 76 34 0,000 0,12897865 0,15090749 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,12897865 0,15083525 ! cholesterol transport GO:0030301 62 34 0,000 0,12897865 0,15076308 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,12897865 0,15069098 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,12897865 0,15061895 ! formation of primary germ layer GO:0001704 76 34 0,000 0,12897865 0,15054699 ! cell fate specification GO:0001708 56 34 0,000 0,12897865 0,15047509 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,12897865 0,15040327 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,12897865 0,15033151 ! adult locomotory behavior GO:0008344 62 34 0,000 0,12897865 0,15025982 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,12897865 0,1501882 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,13251081 0,15422769 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,13251081 0,15415424 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,13251081 0,15408087 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,13251081 0,15400757 ! membrane docking GO:0022406 69 35 0,000 0,13251081 0,15393434 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,13251081 0,15386118 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,13251081 0,15378808 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,13251081 0,15371506 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,13251081 0,1536421 ! ceramide metabolic process GO:0006672 72 35 0,000 0,13251081 0,15356922 ! sterol transport GO:0015918 63 35 0,000 0,13251081 0,1534964 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,13251081 0,15342366 ! placenta development GO:0001890 53 35 0,000 0,13251081 0,15335098 ! vesicle localization GO:0051648 70 35 0,000 0,13251081 0,15327837 ! regulation of muscle development GO:0048634 82 36 0,000 0,13602875 0,15727318 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,13602875 0,15719879 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,13602875 0,15712446 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,13602875 0,15705021 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,13602875 0,15697602 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,13602875 0,15690191 ! positive regulation of cell development GO:0010720 85 36 0,000 0,13602875 0,15682786 ! protein targeting to membrane GO:0006612 75 36 0,000 0,13602875 0,15675388 ! regulation of proteolysis GO:0030162 77 36 0,000 0,13602875 0,15667998 ! aerobic respiration GO:0009060 56 36 0,000 0,13602875 0,15660614 ! cytokine production GO:0001816 68 36 0,000 0,13602875 0,15653238 ! embryonic organ development GO:0048568 67 36 0,000 0,13602875 0,15645868 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,13602875 0,15638505 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,13602875 0,15631149 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,13953252 0,16026232 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,13953252 0,160187 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,13953252 0,16011176 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,13953252 0,16003659 ! sister chromatid segregation GO:0000819 65 37 0,000 0,13953252 0,15996149 ! odontogenesis GO:0042476 74 37 0,000 0,13953252 0,15988647 ! tissue remodeling GO:0048771 78 37 0,000 0,13953252 0,15981151 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,13953252 0,15973662 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,13953252 0,1596618 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,14302218 0,16357827 ! meiosis I GO:0007127 74 38 0,000 0,14302218 0,16350172 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,14302218 0,16342525 ! organic anion transport GO:0015711 82 38 0,000 0,14302218 0,16334885 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,14302218 0,16327251 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,14302218 0,16319625 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,14302218 0,16312007 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,14302218 0,16304395 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,14302218 0,1629679 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,14302218 0,16289193 ! spermatid development GO:0007286 69 38 0,000 0,14302218 0,16281602 ! pigment metabolic process GO:0042440 87 38 0,000 0,14302218 0,16274019 ! neural tube formation GO:0001841 79 38 0,000 0,14302218 0,16266442 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,14649778 0,16653982 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,14649778 0,16646236 ! negative regulation of binding GO:0051100 71 39 0,000 0,14649778 0,16638498 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,14649778 0,16630766 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,14649778 0,16623041 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,14649778 0,16615324 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,14649778 0,16607614 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,14649778 0,16599911 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,14995939 0,16984274 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,14995939 0,16976403 ! learning GO:0007612 82 40 0,000 0,14995939 0,1696854 ! nucleus organization GO:0006997 73 40 0,000 0,14995939 0,16960685 ! lipid homeostasis GO:0055088 75 40 0,000 0,14995939 0,16952836 ! mismatch repair GO:0006298 58 40 0,000 0,14995939 0,16944995 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,14995939 0,16937161 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,14995939 0,16929334 ! RNA export from nucleus GO:0006405 61 41 0,000 0,15340705 0,17310551 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,15340705 0,17302559 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,15340705 0,17294574 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,15340705 0,17286597 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,15340705 0,17278627 ! gliogenesis GO:0042063 91 41 0,000 0,15340705 0,17270665 ! feeding behavior GO:0007631 69 41 0,000 0,15340705 0,1726271 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,15340705 0,17254762 ! mesenchymal cell development GO:0014031 94 41 0,000 0,15340705 0,17246821 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,15340705 0,17238888 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,15340705 0,17230962 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,15340705 0,17223044 ! spermatid differentiation GO:0048515 73 41 0,000 0,15340705 0,17215132 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,15340705 0,17207228 ! RNA modification GO:0009451 64 41 0,000 0,15340705 0,17199331 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,15684083 0,17576245 ! ear morphogenesis GO:0042471 64 42 0,000 0,15684083 0,17568186 ! organic ether metabolic process GO:0018904 59 42 0,000 0,15684083 0,17560135 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,15684083 0,17552091 ! T cell differentiation GO:0030217 93 42 0,000 0,15684083 0,17544054 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,15684083 0,17536025 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,15684083 0,17528003 ! regulation of protein secretion GO:0050708 77 42 0,000 0,15684083 0,17519988 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,15684083 0,17511981 ! cytokinesis GO:0000910 84 42 0,000 0,15684083 0,17503981 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,15684083 0,17495988 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,16026077 0,17869332 GO:0090047|positive regulation of transcription regulator activity, ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,16026077 0,1786118 ! regulation of tube size GO:0035150 76 43 0,000 0,16026077 0,17853036 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,16026077 0,17844899 ! glucose transport GO:0015758 66 43 0,000 0,16026077 0,17836769 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,16026077 0,17828646 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,16026077 0,17820531 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,16026077 0,17812424 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,16026077 0,17804323 ! segmentation GO:0035282 78 43 0,000 0,16026077 0,17796231 ! ion transmembrane transport GO:0034220 79 43 0,000 0,16026077 0,17788145 ! neuron migration GO:0001764 85 43 0,000 0,16026077 0,17780067 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,16366695 0,18149721 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,16366695 0,18141486 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,16366695 0,18133258 ! hexose transport GO:0008645 68 44 0,000 0,16366695 0,18125038 GO:0015749|monosaccharide transport, ! phagocytosis GO:0006909 105 44 0,000 0,16366695 0,18116826 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,16366695 0,18108621 ! double-strand break repair GO:0006302 85 44 0,000 0,16366695 0,18100423 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,16705939 0,18467244 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,16705939 0,18458892 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! B cell differentiation GO:0030183 124 45 0,000 0,16705939 0,18450547 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,16705939 0,1844221 ! female gamete generation GO:0007292 71 45 0,000 0,16705939 0,1843388 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,16705939 0,18425558 ! polyol metabolic process GO:0019751 77 45 0,000 0,16705939 0,18417243 ! developmental growth GO:0048589 88 45 0,000 0,16705939 0,18408936 ! maintenance of location in cell GO:0051651 101 45 0,000 0,16705939 0,18400636 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,17043818 0,18764329 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,17043818 0,18755877 ! glycolysis GO:0006096 71 46 0,000 0,17043818 0,18747432 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,17043818 0,18738995 ! leukocyte migration GO:0050900 75 46 0,000 0,17043818 0,18730565 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,17043818 0,18722143 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,17043818 0,18713729 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,17043818 0,18705322 ! pigmentation GO:0043473 103 46 0,000 0,17043818 0,18696923 ! cell growth GO:0016049 90 46 0,000 0,17043818 0,18688531 ! neural tube development GO:0021915 91 47 0,000 0,17380335 0,19048972 ! positive regulation of defense response GO:0031349 88 48 0,000 0,17715497 0,19407605 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,17715497 0,19398906 ! mitochondrial transport GO:0006839 94 48 0,000 0,17715497 0,19390214 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,17715497 0,19381531 ! cellular component disassembly GO:0022411 89 48 0,000 0,17715497 0,19372855 ! endosome transport GO:0016197 127 48 0,000 0,17715497 0,19364187 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,17715497 0,19355527 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,17715497 0,19346875 ! male sex differentiation GO:0046661 93 48 0,000 0,17715497 0,1933823 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,17715497 0,19329593 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,17715497 0,19320964 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,17715497 0,19312342 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,17715497 0,19303728 ! response to calcium ion GO:0051592 94 49 0,000 0,18049308 0,19658698 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,18049308 0,19649937 ! protein homooligomerization GO:0051260 84 49 0,000 0,18049308 0,19641185 ! regulation of ion transport GO:0043269 86 50 0,000 0,18381775 0,19994067 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,18381775 0,19985169 ! endocrine system development GO:0035270 109 50 0,000 0,18381775 0,19976279 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,18381775 0,19967397 ! activation of caspase activity GO:0006919 95 50 0,000 0,18381775 0,19958522 ! regulation of ossification GO:0030278 123 50 0,000 0,18381775 0,19949656 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,18381775 0,19940797 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,18381775 0,19931947 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,18381775 0,19923104 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,18381775 0,19914269 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,18712902 0,20264015 ! viral infectious cycle GO:0019058 104 51 0,000 0,18712902 0,20255037 ! peptide metabolic process GO:0006518 80 51 0,000 0,18712902 0,20246067 ! response to temperature stimulus GO:0009266 84 51 0,000 0,18712902 0,20237104 ! positive regulation of binding GO:0051099 88 52 0,000 0,19042695 0,20584647 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,19042695 0,20575543 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,19042695 0,20566447 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,19042695 0,20557359 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,19042695 0,20548279 ! excretion GO:0007588 87 52 0,000 0,19042695 0,20539207 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,19042695 0,20530143 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,19042695 0,20521087 ! amino acid activation GO:0043038 98 52 0,000 0,19042695 0,20512038 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! inner ear development GO:0048839 89 53 0,000 0,19371159 0,20856651 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,19371159 0,20847463 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,19371159 0,20838283 ! vesicle organization GO:0016050 127 53 0,000 0,19371159 0,20829111 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,19371159 0,20819948 ! cartilage development GO:0051216 99 53 0,000 0,19371159 0,20810792 ! regulation of translational initiation GO:0006446 87 54 0,000 0,196983 0,21152943 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,196983 0,21143649 ! neuromuscular process GO:0050905 107 54 0,000 0,196983 0,21134364 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,196983 0,21125086 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,196983 0,21115817 ! membrane fusion GO:0006944 122 54 0,000 0,196983 0,21106555 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,196983 0,21097302 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,196983 0,21088057 ! regulation of cell shape GO:0008360 142 54 0,000 0,196983 0,2107882 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,196983 0,21069591 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,20024122 0,21408722 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,20024122 0,21399357 ! cell recognition GO:0008037 98 55 0,000 0,20024122 0,2139 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,20024122 0,21380652 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,20024122 0,21371311 ! glucose catabolic process GO:0006007 88 56 0,000 0,20348632 0,21708169 ! regulation of protein catabolic process GO:0042176 126 56 0,000 0,20348632 0,21698694 ! regulation of DNA replication GO:0006275 105 56 0,000 0,20348632 0,21689227 ! RNA elongation GO:0006354 90 56 0,000 0,20348632 0,21679768 ! chloride transport GO:0006821 102 57 0,000 0,20671834 0,22014512 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,20671834 0,2200492 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,20671834 0,21995336 GO:0010952|positive regulation of peptidase activity, ! nucleotide-excision repair GO:0006289 91 57 0,000 0,20671834 0,2198576 ! regulation of actin filament length GO:0030832 118 58 0,000 0,20993734 0,22318404 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,20993734 0,22308696 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,20993734 0,22298997 ! aging GO:0007568 112 58 0,000 0,20993734 0,22289306 ! gastrulation GO:0007369 122 58 0,000 0,20993734 0,22279623 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,20993734 0,22269949 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,20993734 0,22260283 ! maintenance of location GO:0051235 124 58 0,000 0,20993734 0,22250626 ! nuclear export GO:0051168 110 59 0,000 0,21314336 0,22580626 ! establishment of organelle localization GO:0051656 122 59 0,000 0,21314336 0,22570838 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,21633647 0,22899047 ! DNA catabolic process GO:0006308 94 60 0,000 0,21633647 0,22889129 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,21633647 0,22879221 ! adult behavior GO:0030534 104 60 0,000 0,21633647 0,22869321 ! kidney development GO:0001822 133 60 0,000 0,21633647 0,22859429 ! regulation of cellular component size GO:0032535 125 61 0,000 0,21951671 0,23185444 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,21951671 0,23175424 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,21951671 0,23165413 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,21951671 0,23155411 ! regulation of heart contraction GO:0008016 123 61 0,000 0,21951671 0,23145417 ! camera-type eye development GO:0043010 126 61 0,000 0,21951671 0,23135432 ! proton transport GO:0015992 117 61 0,000 0,21951671 0,23125456 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,21951671 0,23115488 ! viral reproductive process GO:0022415 132 62 0,000 0,22268413 0,2343892 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,22268413 0,23428825 ! tRNA processing GO:0008033 102 62 0,000 0,22268413 0,2341874 ! regulation of mitosis GO:0007088 112 63 0,000 0,22583878 0,23740282 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 0,000 0,22583878 0,23730071 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,22583878 0,23719869 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,22583878 0,23709676 ! hydrogen transport GO:0006818 121 64 0,000 0,22898073 0,24029206 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,22898073 0,24018888 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,22898073 0,2400858 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,23211 0,24326244 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,23211 0,24315812 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,23211 0,2430539 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,23211 0,24294976 ! ear development GO:0043583 114 66 0,000 0,23522667 0,24610653 ! activation of MAPK activity GO:0000187 124 67 0,000 0,23833077 0,24924746 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,23833077 0,24914081 GO:0035113|embryonic appendage morphogenesis, ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,23833077 0,24903425 ! secondary metabolic process GO:0019748 125 67 0,000 0,23833077 0,24892778 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,24142236 0,25204907 ! hexose catabolic process GO:0019320 113 68 0,000 0,24142236 0,25194141 ! extracellular matrix organization GO:0030198 146 68 0,000 0,24142236 0,25183383 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,24142236 0,25172635 ! viral reproduction GO:0016032 142 68 0,000 0,24142236 0,25161895 ! adaptive immune response GO:0002250 126 68 0,000 0,24142236 0,25151165 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 0,000 0,24142236 0,25140445 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,24450149 0,2545024 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,24450149 0,25439401 ! single fertilization GO:0007338 83 69 0,000 0,24450149 0,25428571 ! germ cell development GO:0007281 133 70 0,000 0,24756821 0,25736559 ! activation of immune response GO:0002253 120 70 0,000 0,24756821 0,25725612 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,25062256 0,26031927 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,25062256 0,26020864 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,25062256 0,2600981 ! appendage morphogenesis GO:0035107 150 72 0,000 0,2536646 0,26314337 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,2536646 0,26303168 ! B cell activation GO:0042113 179 72 0,000 0,2536646 0,26292008 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,2536646 0,26280858 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,2536646 0,26269717 ! appendage development GO:0048736 151 73 0,000 0,25669438 0,26572219 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,25669438 0,26560965 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,25669438 0,2654972 ! regulation of immune effector process GO:0002697 156 73 0,000 0,25669438 0,26538484 ! acute inflammatory response GO:0002526 118 74 0,000 0,25971195 0,26839098 ! amino acid transport GO:0006865 148 74 0,000 0,25971195 0,2682775 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,25971195 0,26816411 ! organelle localization GO:0051640 155 74 0,000 0,25971195 0,26805082 ! regulation of transcription factor activity GO:0051090 137 75 0,000 0,26271735 0,27103821 GO:0090046|regulation of transcription regulator activity, ! transition metal ion transport GO:0000041 143 75 0,000 0,26271735 0,2709238 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,26271735 0,27080948 ! eye development GO:0001654 155 75 0,000 0,26271735 0,27069527 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,26571063 0,27366402 ! learning or memory GO:0007611 161 76 0,000 0,26571063 0,2735487 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,26571063 0,27343347 ! regulation of blood pressure GO:0008217 134 76 0,000 0,26571063 0,27331834 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,26571063 0,27320331 ! amine catabolic process GO:0009310 136 77 0,000 0,26869184 0,27615236 ! neurotransmitter transport GO:0006836 142 77 0,000 0,26869184 0,27603623 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,26869184 0,2759202 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,26869184 0,27580427 ! regulation of catabolic process GO:0009894 173 77 0,000 0,26869184 0,27568844 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,27166103 0,27861793 ! antigen processing and presentation GO:0019882 117 78 0,000 0,27166103 0,27850101 ! fertilization GO:0009566 99 78 0,000 0,27166103 0,27838419 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,27461825 0,2812966 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,27461825 0,28117871 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,27461825 0,28106091 ! protein oligomerization GO:0051259 149 79 0,000 0,27461825 0,28094321 ! meiosis GO:0007126 143 81 0,000 0,28049697 0,28683721 GO:0051327|M phase of meiotic cell cycle, ! protein import into nucleus GO:0006606 174 82 0,000 0,28341857 0,28970358 ! meiotic cell cycle GO:0051321 144 82 0,000 0,28341857 0,28958242 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,28632838 0,2924332 ! exocytosis GO:0006887 153 83 0,000 0,28632838 0,292311 ! response to drug GO:0042493 149 83 0,000 0,28632838 0,2921889 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,28632838 0,2920669 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,28632838 0,291945 ! nuclear import GO:0051170 177 83 0,000 0,28632838 0,29182321 ! inorganic anion transport GO:0015698 156 83 0,000 0,28632838 0,29170151 ! response to metal ion GO:0010038 158 84 0,000 0,28922645 0,29453115 ! T cell activation GO:0042110 189 84 0,000 0,28922645 0,29440843 ! response to nutrient GO:0007584 135 84 0,000 0,28922645 0,29428581 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,29211284 0,29709895 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,29211284 0,29697531 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,29498759 0,29977317 ! regulation of lyase activity GO:0051339 169 86 0,000 0,29498759 0,29964852 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,29785075 0,30243116 ! alcohol catabolic process GO:0046164 142 87 0,000 0,29785075 0,30230552 ! nucleosome assembly GO:0006334 126 87 0,000 0,29785075 0,30217998 ! amine biosynthetic process GO:0009309 146 88 0,000 0,30070236 0,30494639 ! sensory perception of smell GO:0007608 117 88 0,000 0,30070236 0,30481986 ! chromatin assembly GO:0031497 128 88 0,000 0,30070236 0,30469343 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,30354247 0,30744372 ! regulation of DNA binding GO:0051101 167 89 0,000 0,30354247 0,30731631 ! cellular defense response GO:0006968 123 89 0,000 0,30354247 0,307189 ! protein localization in nucleus GO:0034504 192 89 0,000 0,30354247 0,3070618 ! response to inorganic substance GO:0010035 173 90 0,000 0,30637112 0,30979497 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,30637112 0,3096668 ! response to unfolded protein GO:0006986 139 90 0,000 0,30637112 0,30953873 ! regulation of cell cycle process GO:0010564 161 90 0,000 0,30637112 0,30941077 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,30918836 0,31212693 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,30918836 0,311998 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,31199424 0,3146994 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,31478881 0,31738714 ! amine transport GO:0015837 181 93 0,000 0,31478881 0,31725621 ! vitamin metabolic process GO:0006766 153 93 0,000 0,31478881 0,31712538 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,3175721 0,31979746 ! female pregnancy GO:0007565 166 94 0,000 0,3175721 0,31966569 ! sterol metabolic process GO:0016125 166 94 0,000 0,3175721 0,31953403 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,3175721 0,31940248 ! regulation of defense response GO:0031347 171 95 0,000 0,32034416 0,32205793 ! nucleosome organization GO:0034728 143 95 0,000 0,32034416 0,32192545 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,32034416 0,32179308 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,32034416 0,32166082 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,32034416 0,32152867 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,32034416 0,32139662 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,32034416 0,32126469 ! response to protein stimulus GO:0051789 158 96 0,000 0,32310504 0,32390054 ! regulation of DNA metabolic process GO:0051052 188 97 0,000 0,32585478 0,32652306 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,32585478 0,32638919 ! leukocyte differentiation GO:0002521 232 98 0,000 0,32859343 0,32899744 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,32859343 0,32886266 ! mRNA transport GO:0051028 185 100 0,000 0,33403763 0,33417442 ! positive regulation of immune response GO:0050778 175 100 0,000 0,33403763 0,33403763