pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6534-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! G1/S transition of mitotic cell cycle GO:0000082 115 46 7,000 2,285E-10 5,498E-07 ! response to UV GO:0009411 104 53 7,000 7,5E-10 9,022E-07 ! apoptotic mitochondrial changes GO:0008637 41 20 5,000 1,236E-09 9,913E-07 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 7,000 1,371E-09 8,247E-07 ! interphase of mitotic cell cycle GO:0051329 209 95 8,000 4,47E-09 2,151E-06 ! interphase GO:0051325 213 98 8,000 5,899E-09 2,366E-06 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 4,000 3,555E-08 1,222E-05 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 3,000 7,399E-08 2,225E-05 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 3,000 7,399E-08 1,978E-05 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 4,000 8,782E-08 2,113E-05 ! cell structure disassembly during apoptosis GO:0006921 30 21 4,000 1,147E-07 2,509E-05 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 3,000 1,326E-07 2,658E-05 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 3,000 2,2E-07 4,071E-05 ! induction of apoptosis by intracellular signals GO:0008629 93 45 5,000 2,305E-07 3,961E-05 ! positive regulation of cell cycle GO:0045787 89 48 5,000 3,423E-07 5,49E-05 ! insulin receptor signaling pathway GO:0008286 64 26 4,000 3,623E-07 5,448E-05 ! regulation of B cell proliferation GO:0030888 20 12 3,000 5,139E-07 7,273E-05 ! negative regulation of mast cell proliferation GO:0070667 23 12 3,000 5,139E-07 6,869E-05 GO:0042130|negative regulation of T cell proliferation, ! release of cytochrome c from mitochondria GO:0001836 30 14 3,000 1,03E-06 1,304E-04 ! positive regulation of MAP kinase activity GO:0043406 160 93 6,000 1,187E-06 1,428E-04 ! negative regulation of leukocyte proliferation GO:0070664 31 16 3,000 1,856E-06 2,126E-04 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! cellular response to insulin stimulus GO:0032869 82 37 4,000 2,28E-06 2,494E-04 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 3,000 2,415E-06 2,527E-04 ! negative regulation of blood coagulation GO:0030195 24 17 3,000 2,415E-06 2,422E-04 ! negative regulation of B cell activation GO:0050869 13 6 2,000 3,743E-06 3,602E-04 ! negative regulation of T cell activation GO:0050868 40 20 3,000 4,851E-06 4,489E-04 ! negative regulation of coagulation GO:0050819 29 20 3,000 4,851E-06 4,323E-04 ! energy reserve metabolic process GO:0006112 74 43 4,000 4,897E-06 4,208E-04 ! regulation of helicase activity GO:0051095 15 7 2,000 6,522E-06 5,411E-04 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 6,522E-06 5,231E-04 ! fibrinolysis GO:0042730 10 7 2,000 6,522E-06 5,062E-04 ! response to insulin stimulus GO:0032868 95 46 4,000 6,876E-06 5,17E-04 ! apoptotic nuclear changes GO:0030262 32 22 3,000 7,258E-06 5,292E-04 ! cellular response to hormone stimulus GO:0032870 167 82 5,000 8,304E-06 5,876E-04 ! cellular component disassembly GO:0022411 86 48 4,000 8,509E-06 5,849E-04 ! regulation of mast cell proliferation GO:0070666 81 48 4,000 8,509E-06 5,687E-04 ! ER overload response GO:0006983 12 8 2,000 1,039E-05 6,757E-04 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 1,039E-05 6,579E-04 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 3,000 1,045E-05 6,446E-04 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 1,045E-05 6,285E-04 ! mitochondrion organization GO:0007005 148 86 5,000 1,094E-05 6,419E-04 ! regulation of leukocyte proliferation GO:0070663 88 51 4,000 1,151E-05 6,594E-04 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! response to endoplasmic reticulum stress GO:0034976 43 25 3,000 1,238E-05 6,929E-04 ! regulation of blood coagulation GO:0030193 40 25 3,000 1,238E-05 6,771E-04 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 1,457E-05 7,789E-04 GO:0045936|negative regulation of phosphate metabolic process, ! middle ear morphogenesis GO:0042474 14 9 2,000 1,552E-05 8,118E-04 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 3,000 1,703E-05 8,716E-04 ! negative regulation of lymphocyte activation GO:0051250 53 27 3,000 1,703E-05 8,534E-04 ! negative regulation of multicellular organismal process GO:0051241 166 93 5,000 1,715E-05 8,423E-04 ! ER-nuclear signaling pathway GO:0006984 48 28 3,000 1,977E-05 9,515E-04 ! regulation of DNA metabolic process GO:0051052 178 97 5,000 2,182E-05 1,029E-03 ! regulation of coagulation GO:0050818 46 29 3,000 2,283E-05 1,057E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 2,566E-05 1,165E-03 ! cell cycle arrest GO:0007050 213 100 5,000 2,595E-05 1,156E-03 ! negative regulation of leukocyte activation GO:0002695 56 30 3,000 2,623E-05 1,147E-03 ! regulation of B cell activation GO:0050864 50 30 3,000 2,623E-05 1,127E-03 ! response to peptide hormone stimulus GO:0043434 122 61 4,000 2,783E-05 1,175E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 2,000 3,023E-05 1,254E-03 ! positive regulation of catabolic process GO:0009896 64 32 3,000 3,411E-05 1,391E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 2,000 4,013E-05 1,609E-03 ! T cell homeostasis GO:0043029 25 12 2,000 4,013E-05 1,583E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 4,000 4,393E-05 1,705E-03 ! negative regulation of kinase activity GO:0033673 131 68 4,000 4,719E-05 1,802E-03 ! negative regulation of cell size GO:0045792 134 69 4,000 5,064E-05 1,904E-03 ! regulation of monooxygenase activity GO:0032768 33 13 2,000 5,195E-05 1,923E-03 ! negative regulation of cell activation GO:0050866 65 36 3,000 5,487E-05 2E-03 ! negative regulation of transferase activity GO:0051348 140 72 4,000 6,217E-05 2,233E-03 ! nucleus organization GO:0006997 67 38 3,000 6,815E-05 2,411E-03 ! regulation of catabolic process GO:0009894 161 76 4,000 8,058E-05 2,81E-03 ! lymphocyte homeostasis GO:0002260 30 15 2,000 8,195E-05 2,817E-03 ! regulation of T cell proliferation GO:0042129 71 41 3,000 9,224E-05 3,126E-03 ! positive regulation of phosphorylation GO:0042327 129 79 4,000 9,694E-05 3,239E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 4,000 1,092E-04 3,599E-03 GO:0045937|positive regulation of phosphate metabolic process, ! glucose transport GO:0015758 65 43 3,000 1,114E-04 3,622E-03 ! regulation of survival gene product expression GO:0045884 33 17 2,000 1,214E-04 3,896E-03 ! hexose transport GO:0008645 67 44 3,000 1,22E-04 3,862E-03 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 97 45 3,000 1,333E-04 4,165E-03 ! patterning of blood vessels GO:0001569 39 18 2,000 1,451E-04 4,476E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 1,451E-04 4,419E-03 ! regulation of protein transport GO:0051223 154 87 4,000 1,531E-04 4,605E-03 GO:0070201|regulation of establishment of protein localization, ! positive regulation of hormone secretion GO:0046887 32 19 2,000 1,716E-04 5,096E-03 ! activation of caspase activity GO:0006919 84 48 3,000 1,717E-04 5,039E-03 ! peptidyl-serine modification GO:0018209 43 20 2,000 2,01E-04 5,827E-03 ! camera-type eye morphogenesis GO:0048593 42 20 2,000 2,01E-04 5,757E-03 ! negative regulation of immune system process GO:0002683 95 50 3,000 2,014E-04 5,702E-03 ! regulation of vasoconstriction GO:0019229 39 21 2,000 2,335E-04 6,533E-03 ! positive regulation of growth GO:0045927 90 52 3,000 2,347E-04 6,49E-03 ! morphogenesis of a branching structure GO:0001763 111 52 3,000 2,347E-04 6,417E-03 ! regulation of protein localization GO:0032880 176 97 4,000 2,55E-04 6,893E-03 ! positive regulation of protein catabolic process GO:0045732 38 22 2,000 2,692E-04 7,197E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 2,692E-04 7,118E-03 ! positive regulation of caspase activity GO:0043280 95 55 3,000 2,917E-04 7,629E-03 GO:0010952|positive regulation of peptidase activity, ! regulation of protein catabolic process GO:0042176 116 55 3,000 2,917E-04 7,547E-03 ! aging GO:0007568 103 55 3,000 2,917E-04 7,466E-03 ! gluconeogenesis GO:0006094 33 23 2,000 3,083E-04 7,808E-03 ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 3,083E-04 7,727E-03 ! regulation of DNA replication GO:0006275 101 56 3,000 3,127E-04 7,757E-03 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 1,000 3,281E-04 8,055E-03 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of helicase activity GO:0051096 11 5 1,000 3,281E-04 7,974E-03 ! female meiosis GO:0007143 7 5 1,000 3,281E-04 7,894E-03 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 1,000 3,281E-04 7,816E-03 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 3,281E-04 7,74E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 3,281E-04 7,664E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 3,281E-04 7,591E-03 ! anagen GO:0042640 6 5 1,000 3,281E-04 7,518E-03 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 3,281E-04 7,447E-03 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 1,000 3,281E-04 7,378E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 3,281E-04 7,31E-03 ! microvillus organization GO:0032528 7 5 1,000 3,281E-04 7,242E-03 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 1,000 3,281E-04 7,177E-03 ! muscle cell migration GO:0014812 8 5 1,000 3,281E-04 7,112E-03 ! response to food GO:0032094 6 5 1,000 3,281E-04 7,048E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 3,281E-04 6,986E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 3,281E-04 6,925E-03 ! B cell homeostasis GO:0001782 13 5 1,000 3,281E-04 6,865E-03 ! stem cell division GO:0017145 11 5 1,000 3,281E-04 6,805E-03 GO:0048103|somatic stem cell division, ! positive regulation of cell migration GO:0030335 126 57 3,000 3,348E-04 6,885E-03 ! protein import into nucleus, translocation GO:0000060 46 24 2,000 3,508E-04 7,154E-03 ! regulation of cellular catabolic process GO:0031329 52 24 2,000 3,508E-04 7,094E-03 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 3,508E-04 7,035E-03 ! leukocyte homeostasis GO:0001776 44 24 2,000 3,508E-04 6,976E-03 ! protein tetramerization GO:0051262 52 24 2,000 3,508E-04 6,919E-03 ! DNA catabolic process GO:0006308 86 59 3,000 3,823E-04 7,479E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 3,97E-04 7,703E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 3,97E-04 7,642E-03 ! negative regulation of cell development GO:0010721 73 25 2,000 3,97E-04 7,581E-03 GO:0050768|negative regulation of neurogenesis, ! pyruvate metabolic process GO:0006090 38 26 2,000 4,469E-04 8,466E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 4,469E-04 8,4E-03 ! positive regulation of nuclear division GO:0051785 40 26 2,000 4,469E-04 8,335E-03 GO:0045840|positive regulation of mitosis, ! ear development GO:0043583 103 62 3,000 4,624E-04 8,557E-03 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 1,000 4,903E-04 9,005E-03 ! vascular smooth muscle contraction GO:0014829 13 6 1,000 4,903E-04 8,937E-03 ! positive regulation of muscle hypertrophy GO:0014742 10 6 1,000 4,903E-04 8,869E-03 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! neuron apoptosis GO:0051402 9 6 1,000 4,903E-04 8,803E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 4,903E-04 8,738E-03 ! male sex determination GO:0030238 15 6 1,000 4,903E-04 8,674E-03 ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 4,903E-04 8,611E-03 ! negative regulation of gliogenesis GO:0014014 18 6 1,000 4,903E-04 8,548E-03 GO:0045686|negative regulation of glial cell differentiation, ! hair follicle maturation GO:0048820 7 6 1,000 4,903E-04 8,487E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 4,903E-04 8,426E-03 ! progesterone metabolic process GO:0042448 10 6 1,000 4,903E-04 8,366E-03 ! determination of adult lifespan GO:0008340 15 6 1,000 4,903E-04 8,307E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 5,006E-04 8,423E-03 ! positive regulation of cell motion GO:0051272 146 64 3,000 5,219E-04 8,721E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 5,583E-04 9,264E-03 ! regulation of pH GO:0006885 43 29 2,000 6,201E-04 0,01021902 ! cellular iron ion homeostasis GO:0006879 51 29 2,000 6,201E-04 0,0101495 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 6,201E-04 0,01008092 ! tissue homeostasis GO:0001894 48 29 2,000 6,201E-04 0,01001326 GO:0048871|multicellular organismal homeostasis, ! negative regulation of cell growth GO:0030308 132 67 3,000 6,212E-04 9,964E-03 ! activation of MAPK activity GO:0000187 115 67 3,000 6,212E-04 9,898E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 3,000 6,212E-04 9,833E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 6,838E-04 0,01075309 ! positive regulation of heart rate GO:0010460 10 7 1,000 6,838E-04 0,01068327 ! induction of apoptosis by oxidative stress GO:0008631 8 7 1,000 6,838E-04 0,01061434 ! regulation of granule cell precursor proliferation GO:0021936 13 7 1,000 6,838E-04 0,0105463 GO:0021940|positive regulation of granule cell precursor proliferation, ! phasic smooth muscle contraction GO:0014821 12 7 1,000 6,838E-04 0,01047913 ! melanosome organization GO:0032438 9 7 1,000 6,838E-04 0,01041281 ! negative regulation of DNA recombination GO:0045910 15 7 1,000 6,838E-04 0,01034732 ! B cell lineage commitment GO:0002326 21 7 1,000 6,838E-04 0,01028265 ! prostate gland development GO:0030850 13 7 1,000 6,838E-04 0,01021878 ! oxaloacetate metabolic process GO:0006107 10 7 1,000 6,838E-04 0,0101557 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 6,838E-04 0,01009339 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 6,838E-04 0,01003185 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 6,838E-04 9,971E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 6,838E-04 9,911E-03 ! response to tumor cell GO:0002347 13 7 1,000 6,838E-04 9,852E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 6,838E-04 9,793E-03 ! diuresis GO:0030146 12 7 1,000 6,838E-04 9,735E-03 GO:0030147|natriuresis, ! negative regulation of nucleotide metabolic process GO:0045980 11 7 1,000 6,838E-04 9,678E-03 ! positive regulation of smooth muscle contraction GO:0045987 10 7 1,000 6,838E-04 9,621E-03 ! positive regulation of multicellular organism growth GO:0040018 51 30 2,000 6,861E-04 9,597E-03 ! eye morphogenesis GO:0048592 60 30 2,000 6,861E-04 9,542E-03 ! cell cycle checkpoint GO:0000075 137 69 3,000 6,944E-04 9,602E-03 ! iron ion homeostasis GO:0055072 54 31 2,000 7,564E-04 0,01039929 ! regulation of caspase activity GO:0043281 122 72 3,000 8,154E-04 0,01114644 ! carbohydrate transport GO:0008643 110 72 3,000 8,154E-04 0,01108347 ! hexose biosynthetic process GO:0019319 48 32 2,000 8,311E-04 0,01123399 ! regulation of endopeptidase activity GO:0052548 125 74 3,000 9,038E-04 0,01214835 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 9,083E-04 0,01214054 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 1,000 9,083E-04 0,01207347 GO:0016446|somatic hypermutation of immunoglobulin genes, ! succinate metabolic process GO:0006105 14 8 1,000 9,083E-04 0,01200713 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 9,083E-04 0,01194152 ! inositol phosphate-mediated signaling GO:0048016 11 8 1,000 9,083E-04 0,01187662 ! pigment granule organization GO:0048753 16 8 1,000 9,083E-04 0,01181242 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 9,083E-04 0,01174891 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 1,000 9,083E-04 0,01168608 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 9,083E-04 0,01162392 ! regulation of muscle hypertrophy GO:0014743 12 8 1,000 9,083E-04 0,01156242 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 9,083E-04 0,01150157 ! positive regulation of insulin secretion GO:0032024 15 8 1,000 9,083E-04 0,01144135 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 9,083E-04 0,01138176 ! multicellular organismal aging GO:0010259 18 8 1,000 9,083E-04 0,01132279 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 2,000 1,083E-03 0,01342962 ! calcium-mediated signaling GO:0019722 62 35 2,000 1,083E-03 0,01336075 ! negative regulation of secretion GO:0051048 63 35 2,000 1,083E-03 0,01329258 ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 1,083E-03 0,0132251 ! activation of protein kinase activity GO:0032147 147 79 3,000 1,154E-03 0,01402414 ! regulation of peptidase activity GO:0052547 134 79 3,000 1,154E-03 0,01395366 ! regulation of developmental growth GO:0048638 15 9 1,000 1,163E-03 0,013995 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,163E-03 0,01392537 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 1,163E-03 0,01385643 GO:0010469|regulation of receptor activity, ! regulation of activated T cell proliferation GO:0046006 16 9 1,000 1,163E-03 0,01378817 ! regulation of glycolysis GO:0006110 21 9 1,000 1,163E-03 0,01372058 ! microtubule bundle formation GO:0001578 21 9 1,000 1,163E-03 0,01365365 ! phosphagen metabolic process GO:0006599 12 9 1,000 1,163E-03 0,01358737 GO:0006600|creatine metabolic process, ! retinol metabolic process GO:0042572 18 9 1,000 1,163E-03 0,01352174 ! motor axon guidance GO:0008045 16 9 1,000 1,163E-03 0,01345673 ! protein heterooligomerization GO:0051291 16 9 1,000 1,163E-03 0,01339234 ! establishment of melanosome localization GO:0032401 14 9 1,000 1,163E-03 0,01332857 ! renal water homeostasis GO:0003091 14 9 1,000 1,163E-03 0,0132654 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,163E-03 0,01320283 ! regulation of muscle adaptation GO:0043502 14 9 1,000 1,163E-03 0,01314084 ! regulation of proteolysis GO:0030162 72 36 2,000 1,176E-03 0,0132252 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 1,176E-03 0,01316369 ! monosaccharide biosynthetic process GO:0046364 52 36 2,000 1,176E-03 0,01310274 ! response to hypoxia GO:0001666 171 81 3,000 1,267E-03 0,01404336 ! monovalent inorganic cation homeostasis GO:0055067 58 37 2,000 1,275E-03 0,01406841 ! glycogen metabolic process GO:0005977 61 37 2,000 1,275E-03 0,01400417 ! carbohydrate homeostasis GO:0033500 53 38 2,000 1,378E-03 0,01507153 GO:0042593|glucose homeostasis, ! glucan metabolic process GO:0044042 62 38 2,000 1,378E-03 0,01500334 GO:0006073|cellular glucan metabolic process, ! response to oxygen levels GO:0070482 176 83 3,000 1,387E-03 0,01502685 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 1,449E-03 0,01562991 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,449E-03 0,01556013 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,449E-03 0,01549098 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,449E-03 0,01542243 ! positive regulation of heart contraction GO:0045823 16 10 1,000 1,449E-03 0,01535449 ! glucan biosynthetic process GO:0009250 14 10 1,000 1,449E-03 0,01528715 GO:0005978|glycogen biosynthetic process, ! lens development in camera-type eye GO:0002088 16 10 1,000 1,449E-03 0,01522039 ! positive regulation of muscle contraction GO:0045933 14 10 1,000 1,449E-03 0,01515422 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 1,449E-03 0,01508861 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,449E-03 0,01502358 GO:0045685|regulation of glial cell differentiation, ! melanosome localization GO:0032400 16 10 1,000 1,449E-03 0,0149591 ! apical protein localization GO:0045176 15 10 1,000 1,449E-03 0,01489517 ! multicellular organismal water homeostasis GO:0050891 15 10 1,000 1,449E-03 0,01483178 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,449E-03 0,01476894 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 1,000 1,449E-03 0,01470662 ! establishment of pigment granule localization GO:0051905 18 10 1,000 1,449E-03 0,01464483 ! localization within membrane GO:0051668 20 10 1,000 1,449E-03 0,01458355 ! negative regulation of transport GO:0051051 153 84 3,000 1,449E-03 0,0145298 ! negative regulation of growth GO:0045926 155 84 3,000 1,449E-03 0,01446951 ! ear morphogenesis GO:0042471 60 39 2,000 1,487E-03 0,01478055 ! tube morphogenesis GO:0035239 176 86 3,000 1,581E-03 0,01565328 ! regulation of hormone secretion GO:0046883 62 40 2,000 1,6E-03 0,01578114 ! keratinocyte differentiation GO:0030216 62 41 2,000 1,719E-03 0,01688601 ! regulation of T cell differentiation GO:0045580 70 41 2,000 1,719E-03 0,01681737 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,764E-03 0,01718161 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,764E-03 0,01711233 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,764E-03 0,0170436 ! negative regulation of proteolysis GO:0045861 25 11 1,000 1,764E-03 0,01697543 ! regulation of intracellular pH GO:0051453 19 11 1,000 1,764E-03 0,0169078 ! positive regulation of peptide secretion GO:0002793 22 11 1,000 1,764E-03 0,0168407 ! pigment granule localization GO:0051875 20 11 1,000 1,764E-03 0,01677414 ! vasoconstriction GO:0042310 18 11 1,000 1,764E-03 0,0167081 ! neuroblast proliferation GO:0007405 24 11 1,000 1,764E-03 0,01664258 ! oocyte differentiation GO:0009994 18 11 1,000 1,764E-03 0,01657756 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 1,000 1,764E-03 0,01651306 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! regulation of embryonic development GO:0045995 27 11 1,000 1,764E-03 0,01644906 ! negative regulation of protein complex disassembly GO:0043242 101 42 2,000 1,844E-03 0,01712944 ! alcohol biosynthetic process GO:0046165 59 42 2,000 1,844E-03 0,01706356 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 1,844E-03 0,01699818 ! regulation of protein secretion GO:0050708 71 42 2,000 1,844E-03 0,0169333 ! ossification GO:0001503 188 90 3,000 1,869E-03 0,0170948 ! regulation of cell cycle process GO:0010564 149 90 3,000 1,869E-03 0,01703005 ! bone development GO:0060348 189 91 3,000 1,946E-03 0,01766685 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 1,974E-03 0,01785399 ! carbohydrate biosynthetic process GO:0016051 141 93 3,000 2,107E-03 0,01898536 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 1,000 2,109E-03 0,01893029 ! virus-host interaction GO:0019048 29 12 1,000 2,109E-03 0,01885991 ! cartilage condensation GO:0001502 20 12 1,000 2,109E-03 0,01879006 ! hippocampus development GO:0021766 26 12 1,000 2,109E-03 0,01872072 ! asymmetric protein localization GO:0008105 20 12 1,000 2,109E-03 0,0186519 ! immunoglobulin production during immune response GO:0002381 23 12 1,000 2,109E-03 0,01858358 ! histone acetylation GO:0016573 26 12 1,000 2,109E-03 0,01851575 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,109E-03 0,01844842 ! transcription initiation GO:0006352 153 94 3,000 2,191E-03 0,01909724 ! regulation of T cell activation GO:0050863 158 94 3,000 2,191E-03 0,01902829 ! cell growth GO:0016049 84 45 2,000 2,251E-03 0,01947767 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 2,397E-03 0,02067446 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 2,397E-03 0,02060062 ! epidermal cell differentiation GO:0009913 68 46 2,000 2,397E-03 0,02052731 ! pigmentation GO:0043473 100 46 2,000 2,397E-03 0,02045452 ! positive regulation of protein transport GO:0051222 72 46 2,000 2,397E-03 0,02038224 ! response to X-ray GO:0010165 25 13 1,000 2,483E-03 0,02103173 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,483E-03 0,02095794 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 2,483E-03 0,02088466 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 2,709E-03 0,02270733 ! regulation of protein complex disassembly GO:0043244 113 49 2,000 2,873E-03 0,02400283 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 2,885E-03 0,02402115 ! retina development in camera-type eye GO:0060041 27 14 1,000 2,885E-03 0,02393832 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 2,885E-03 0,02385606 ! regulation of mRNA processing GO:0050684 24 14 1,000 2,885E-03 0,02377436 ! regulation of heart rate GO:0002027 24 14 1,000 2,885E-03 0,02369322 ! bone mineralization GO:0030282 17 14 1,000 2,885E-03 0,02361263 ! response to gamma radiation GO:0010332 28 14 1,000 2,885E-03 0,02353259 ! cAMP biosynthetic process GO:0006171 23 14 1,000 2,885E-03 0,02345309 ! positive regulation of cell size GO:0045793 27 15 1,000 3,317E-03 0,02686801 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 3,317E-03 0,02677784 ! G1/S transition checkpoint GO:0031575 40 15 1,000 3,317E-03 0,02668829 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 3,317E-03 0,02659933 ! water homeostasis GO:0030104 27 15 1,000 3,317E-03 0,02651096 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 1,000 3,317E-03 0,02642317 ! regulation of angiogenesis GO:0045765 114 52 2,000 3,403E-03 0,02702276 ! cartilage development GO:0051216 90 52 2,000 3,403E-03 0,02693387 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,776E-03 0,0297877 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 3,776E-03 0,02969036 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 3,776E-03 0,02959365 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 3,776E-03 0,02949756 ! activation of MAPKK activity GO:0000186 35 16 1,000 3,776E-03 0,0294021 ! induction of apoptosis via death domain receptors GO:0008625 20 16 1,000 3,776E-03 0,02930726 ! response to osmotic stress GO:0006970 25 16 1,000 3,776E-03 0,02921302 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 3,776E-03 0,02911939 GO:0031114|regulation of microtubule depolymerization, ! DNA replication initiation GO:0006270 27 16 1,000 3,776E-03 0,02902636 ! biomineral formation GO:0031214 20 16 1,000 3,776E-03 0,02893392 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 3,776E-03 0,02884206 ! activation of phospholipase C activity GO:0007202 103 54 2,000 3,787E-03 0,02883743 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 2,000 3,787E-03 0,02874646 ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 3,989E-03 0,03018197 ! positive regulation of phospholipase activity GO:0010518 104 55 2,000 3,989E-03 0,03008735 ! heart morphogenesis GO:0003007 97 55 2,000 3,989E-03 0,02999333 ! regulation of multicellular organism growth GO:0040014 85 55 2,000 3,989E-03 0,02989989 ! positive regulation of organelle organization GO:0010638 100 56 2,000 4,197E-03 0,03136195 ! cardiac muscle tissue development GO:0048738 31 17 1,000 4,263E-03 0,03175746 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 4,263E-03 0,03165945 ! genitalia development GO:0048806 30 17 1,000 4,263E-03 0,03156203 ! neutrophil chemotaxis GO:0030593 27 17 1,000 4,263E-03 0,03146522 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 4,263E-03 0,03136899 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 4,263E-03 0,03127336 ! negative regulation of hormone secretion GO:0046888 25 17 1,000 4,263E-03 0,0311783 ! limbic system development GO:0021761 36 17 1,000 4,263E-03 0,03108382 ! regulation of muscle cell differentiation GO:0051147 33 17 1,000 4,263E-03 0,03098991 ! regulation of phospholipase activity GO:0010517 106 57 2,000 4,412E-03 0,03197236 ! regulation of intracellular transport GO:0032386 101 57 2,000 4,412E-03 0,03187635 ! positive regulation of lipase activity GO:0060193 108 58 2,000 4,633E-03 0,03337374 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 4,778E-03 0,0343171 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 1,000 4,778E-03 0,03421497 GO:0050886|endocrine process, ! positive regulation of proteolysis GO:0045862 31 18 1,000 4,778E-03 0,03411344 ! response to retinoic acid GO:0032526 26 18 1,000 4,778E-03 0,03401251 ! vitamin transport GO:0051180 27 18 1,000 4,778E-03 0,03391218 ! regulation of immunoglobulin production GO:0002637 43 18 1,000 4,778E-03 0,03381244 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 4,778E-03 0,03371328 ! positive regulation of secretion GO:0051047 95 59 2,000 4,861E-03 0,03419503 ! skeletal system morphogenesis GO:0048705 105 59 2,000 4,861E-03 0,03409533 ! integrin-mediated signaling pathway GO:0007229 135 59 2,000 4,861E-03 0,03399622 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 5,095E-03 0,03553208 ! camera-type eye development GO:0043010 116 60 2,000 5,095E-03 0,03542938 ! lipid phosphorylation GO:0046834 35 19 1,000 5,32E-03 0,03688807 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 5,32E-03 0,03678207 ! cellular response to unfolded protein GO:0034620 33 19 1,000 5,32E-03 0,03667668 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 1,000 5,32E-03 0,03657189 ! actin filament bundle formation GO:0051017 42 19 1,000 5,32E-03 0,03646769 ! neuromuscular junction development GO:0007528 34 19 1,000 5,32E-03 0,03636409 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 5,32E-03 0,03626108 ! peptide cross-linking GO:0018149 37 19 1,000 5,32E-03 0,03615865 ! cellular pigmentation GO:0033059 36 19 1,000 5,32E-03 0,03605679 ! G1 phase GO:0051318 40 19 1,000 5,32E-03 0,03595551 ! cell-cell junction organization GO:0045216 35 19 1,000 5,32E-03 0,03585479 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 1,000 5,32E-03 0,03575464 ! embryonic organ morphogenesis GO:0048562 26 19 1,000 5,32E-03 0,03565504 ! peptide hormone secretion GO:0030072 31 19 1,000 5,32E-03 0,035556 ! regulation of mitosis GO:0007088 105 63 2,000 5,838E-03 0,0389125 GO:0051783|regulation of nuclear division, ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 5,838E-03 0,03880501 ! protein amino acid acetylation GO:0006473 39 20 1,000 5,889E-03 0,03903214 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 5,889E-03 0,03892491 ! cAMP metabolic process GO:0046058 36 20 1,000 5,889E-03 0,03881827 ! response to vitamin GO:0033273 31 20 1,000 5,889E-03 0,03871221 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 5,889E-03 0,03860672 GO:0010675|regulation of cellular carbohydrate metabolic process, ! C21-steroid hormone metabolic process GO:0008207 33 20 1,000 5,889E-03 0,03850181 ! response to alkaloid GO:0043279 38 20 1,000 5,889E-03 0,03839747 ! retinoid metabolic process GO:0001523 32 20 1,000 5,889E-03 0,0382937 GO:0016101|diterpenoid metabolic process, ! cellular response to starvation GO:0009267 33 20 1,000 5,889E-03 0,03819048 ! body fluid secretion GO:0007589 31 20 1,000 5,889E-03 0,03808781 ! peptide secretion GO:0002790 35 20 1,000 5,889E-03 0,0379857 ! negative regulation of translation GO:0017148 29 20 1,000 5,889E-03 0,03788414 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 5,889E-03 0,03778311 ! germ cell development GO:0007281 118 65 2,000 6,368E-03 0,04075055 ! hormone secretion GO:0046879 38 21 1,000 6,484E-03 0,04138188 ! smooth muscle contraction GO:0006939 46 21 1,000 6,484E-03 0,0412724 ! cell aging GO:0007569 44 21 1,000 6,484E-03 0,0411635 ! cytolysis GO:0019835 24 21 1,000 6,484E-03 0,04105518 ! oogenesis GO:0048477 36 21 1,000 6,484E-03 0,04094742 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 6,484E-03 0,04084023 ! vitamin A metabolic process GO:0006776 33 21 1,000 6,484E-03 0,0407336 ! terpenoid metabolic process GO:0006721 37 21 1,000 6,484E-03 0,04062752 ! developmental maturation GO:0021700 116 66 2,000 6,644E-03 0,04151846 ! cellular hormone metabolic process GO:0034754 113 67 2,000 6,926E-03 0,04317053 ! lung development GO:0030324 144 67 2,000 6,926E-03 0,04305898 ! homeostasis of number of cells GO:0048872 114 67 2,000 6,926E-03 0,042948 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 7,106E-03 0,04394933 ! keratinization GO:0031424 28 22 1,000 7,106E-03 0,04383664 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 7,106E-03 0,04372452 ! positive regulation of cytoskeleton organization GO:0051495 48 22 1,000 7,106E-03 0,04361298 ! renal system process GO:0003014 41 22 1,000 7,106E-03 0,04350201 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 7,106E-03 0,0433916 ! positive regulation of B cell activation GO:0050871 38 22 1,000 7,106E-03 0,04328174 ! somatic diversification of immunoglobulins GO:0016445 50 22 1,000 7,106E-03 0,04317245 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 7,106E-03 0,0430637 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 7,215E-03 0,04361798 ! regulation of lipase activity GO:0060191 130 68 2,000 7,215E-03 0,04350866 ! urogenital system development GO:0001655 137 69 2,000 7,512E-03 0,04518275 ! positive regulation of DNA replication GO:0045740 43 23 1,000 7,753E-03 0,04651836 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 7,753E-03 0,04640264 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 7,753E-03 0,0462875 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 7,753E-03 0,04617293 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 1,000 7,753E-03 0,04605892 ! sex determination GO:0007530 47 23 1,000 7,753E-03 0,04594547 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 7,753E-03 0,04583259 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 1,000 7,753E-03 0,04572025 ! hormone transport GO:0009914 40 23 1,000 7,753E-03 0,04560847 ! negative regulation of catabolic process GO:0009895 50 23 1,000 7,753E-03 0,04549722 ! respiratory tube development GO:0030323 150 70 2,000 7,815E-03 0,04575025 ! reproductive structure development GO:0048608 113 71 2,000 8,126E-03 0,04745341 ! B cell activation GO:0042113 160 71 2,000 8,126E-03 0,04733851 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 8,426E-03 0,04896842 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 1,000 8,426E-03 0,04885043 GO:0016444|somatic cell DNA recombination, ! digestive system process GO:0022600 39 24 1,000 8,426E-03 0,048733 ! membrane depolarization GO:0051899 39 24 1,000 8,426E-03 0,04861613 ! pallium development GO:0021543 49 24 1,000 8,426E-03 0,04849983 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 8,444E-03 0,04848579 ! respiratory system development GO:0060541 153 72 2,000 8,444E-03 0,04837035 ! regulation of transcription factor activity GO:0051090 126 74 2,000 9,101E-03 0,05201241 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 121 74 2,000 9,101E-03 0,05188916 GO:0051327|M phase of meiotic cell cycle, ! regulation of actin cytoskeleton organization GO:0032956 149 74 2,000 9,101E-03 0,05176649 ! eye development GO:0001654 143 74 2,000 9,101E-03 0,0516444 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 9,124E-03 0,05165348 ! myelination GO:0042552 45 25 1,000 9,124E-03 0,05153223 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 9,124E-03 0,05141155 ! regulation of smooth muscle contraction GO:0006940 43 25 1,000 9,124E-03 0,05129143 ! negative regulation of DNA replication GO:0008156 42 25 1,000 9,124E-03 0,05117187 ! response to starvation GO:0042594 42 25 1,000 9,124E-03 0,05105286 ! neural crest cell development GO:0014032 54 25 1,000 9,124E-03 0,05093441 GO:0014033|neural crest cell differentiation, ! regulation of insulin secretion GO:0050796 37 25 1,000 9,124E-03 0,05081651 ! interaction with host GO:0051701 62 25 1,000 9,124E-03 0,05069915 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 9,124E-03 0,05058233 ! somitogenesis GO:0001756 43 25 1,000 9,124E-03 0,05046605 ! immunoglobulin production GO:0002377 55 25 1,000 9,124E-03 0,0503503 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 36 25 1,000 9,124E-03 0,05023508 ! cellular response to nutrient levels GO:0031669 41 25 1,000 9,124E-03 0,05012039 ! cell-matrix adhesion GO:0007160 163 75 2,000 9,441E-03 0,05174106 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 9,441E-03 0,05162347 ! meiotic cell cycle GO:0051321 122 75 2,000 9,441E-03 0,05150641 ! negative regulation of actin filament depolymerization GO:0030835 55 26 1,000 9,847E-03 0,053603 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 9,847E-03 0,053482 ! molting cycle process GO:0022404 50 26 1,000 9,847E-03 0,05336154 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! somatic diversification of immune receptors GO:0002200 56 26 1,000 9,847E-03 0,05324163 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 9,847E-03 0,05312225 ! regulation of actin filament-based process GO:0032970 152 77 2,000 0,01014191 0,05458932 ! blood coagulation GO:0007596 146 78 2,000 0,01050356 0,05640973 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 2,000 0,01050356 0,0562841 ! negative regulation of organelle organization GO:0010639 161 78 2,000 0,01050356 0,05615902 ! protein oligomerization GO:0051259 139 78 2,000 0,01050356 0,0560345 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 0,010595 0,05639727 ! iron ion transport GO:0006826 59 27 1,000 0,010595 0,05627278 ! protein amino acid acylation GO:0043543 55 27 1,000 0,010595 0,05614883 ! fat cell differentiation GO:0045444 50 27 1,000 0,010595 0,05602542 ! mitochondrial membrane organization GO:0007006 57 27 1,000 0,010595 0,05590256 ! base-excision repair GO:0006284 41 27 1,000 0,010595 0,05578024 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 1,000 0,010595 0,05565844 ! regulation of chromosome organization GO:0033044 42 27 1,000 0,010595 0,05553718 ! fat-soluble vitamin metabolic process GO:0006775 40 27 1,000 0,010595 0,05541645 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 0,010595 0,05529624 ! regulation of synaptic transmission GO:0050804 134 79 2,000 0,01087262 0,05662232 ! protein import into nucleus GO:0006606 158 80 2,000 0,0112491 0,05845646 ! regulation of actin filament depolymerization GO:0030834 58 28 1,000 0,01136705 0,05894208 ! dendrite development GO:0016358 59 28 1,000 0,01136705 0,05881532 ! negative regulation of protein modification process GO:0031400 60 28 1,000 0,01136705 0,05868911 ! regulation of systemic arterial blood pressure GO:0003073 54 28 1,000 0,01136705 0,05856344 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 0,01136705 0,0584383 ! cell-substrate adhesion GO:0031589 171 81 2,000 0,01163305 0,05967827 ! nuclear import GO:0051170 161 81 2,000 0,01163305 0,0595513 ! regulation of neuron differentiation GO:0045664 167 81 2,000 0,01163305 0,05942486 ! response to drug GO:0042493 143 82 2,000 0,01202447 0,06129422 ! respiratory gaseous exchange GO:0007585 57 29 1,000 0,01216312 0,06186991 ! regulation of peptide secretion GO:0002791 47 29 1,000 0,01216312 0,06173939 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 0,01216312 0,06160941 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 0,01216312 0,06147998 ! hemostasis GO:0007599 158 84 2,000 0,01282984 0,06471402 ! regulation of transmission of nerve impulse GO:0051969 141 84 2,000 0,01282984 0,06457863 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 1,000 0,01298291 0,06521269 ! ensheathment of neurons GO:0007272 57 30 1,000 0,01298291 0,06507683 GO:0008366|axon ensheathment, ! response to heat GO:0009408 50 30 1,000 0,01298291 0,06494154 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 0,01382612 0,06901585 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 0,01382612 0,06887296 ! peptide transport GO:0015833 55 31 1,000 0,01382612 0,06873066 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 0,01382612 0,06858894 GO:0043433|negative regulation of transcription factor activity, ! protein localization in nucleus GO:0034504 176 87 2,000 0,0140945 0,0697765 ! positive regulation of protein modification process GO:0031401 136 88 2,000 0,01453123 0,07179084 ! regulation of DNA binding GO:0051101 155 88 2,000 0,01453123 0,07164373 ! gland development GO:0048732 206 88 2,000 0,01453123 0,07149722 ! regulation of neurological system process GO:0031644 148 88 2,000 0,01453123 0,07135131 ! spliceosome assembly GO:0000245 67 32 1,000 0,01469245 0,071996 ! response to ionizing radiation GO:0010212 65 32 1,000 0,01469245 0,07184967 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01469245 0,07170393 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01469245 0,07155878 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,01497557 0,07279033 ! sex differentiation GO:0007548 145 90 2,000 0,01542753 0,07483596 ! DNA damage checkpoint GO:0000077 71 33 1,000 0,01558162 0,07543134 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,01558162 0,07527987 ! leukocyte chemotaxis GO:0030595 50 33 1,000 0,01558162 0,07512901 GO:0060326|cell chemotaxis, ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01558162 0,07497875 ! establishment of vesicle localization GO:0051650 61 33 1,000 0,01558162 0,07482909 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 0,01649333 0,0790497 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,01649333 0,07889255 ! mismatch repair GO:0006298 46 34 1,000 0,01649333 0,07873601 ! placenta development GO:0001890 53 34 1,000 0,01649333 0,0785801 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,01649333 0,0784248 ! regulation of membrane potential GO:0042391 164 93 2,000 0,01682931 0,07986452 ! regulation of muscle development GO:0048634 70 35 1,000 0,0174273 0,08253953 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 0,0174273 0,08237736 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,0174273 0,08221584 ! telencephalon development GO:0021537 68 35 1,000 0,0174273 0,08205495 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,0174273 0,08189468 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,0174273 0,08173505 ! vesicle localization GO:0051648 64 35 1,000 0,0174273 0,08157603 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 0,01838324 0,08588363 ! cell junction organization GO:0034330 86 36 1,000 0,01838324 0,08571719 ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,01838324 0,0855514 ! hormone biosynthetic process GO:0042446 57 36 1,000 0,01838324 0,08538624 ! embryonic organ development GO:0048568 57 36 1,000 0,01838324 0,08522172 ! protein ubiquitination GO:0016567 217 97 2,000 0,0188058 0,08701298 ! hormone metabolic process GO:0042445 157 97 2,000 0,0188058 0,08684597 ! meiosis I GO:0007127 65 37 1,000 0,01936087 0,08923803 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,01936087 0,0890674 ! cyclic nucleotide metabolic process GO:0009187 63 37 1,000 0,01936087 0,08889743 ! regulation of protein stability GO:0031647 73 37 1,000 0,01936087 0,0887281 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,01984024 0,09075214 GO:0060538|skeletal muscle organ development, ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,02035991 0,09295246 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,02035991 0,09277642 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,02035991 0,09260104 GO:0046660|female sex differentiation, ! isoprenoid metabolic process GO:0006720 66 38 1,000 0,02035991 0,09242632 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,02035991 0,09225226 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 1,000 0,02138009 0,09669265 ! learning GO:0007612 77 39 1,000 0,02138009 0,09651124 ! segmentation GO:0035282 67 39 1,000 0,02138009 0,09633051 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,02138009 0,09615045 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,02242112 0,10064407 ! negative regulation of binding GO:0051100 72 40 1,000 0,02242112 0,10045665 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,02242112 0,10026993 ! mesenchymal cell development GO:0014031 87 40 1,000 0,02242112 0,1000839 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 1,000 0,02348275 0,10462868 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,02348275 0,10443528 ! T cell differentiation GO:0030217 81 41 1,000 0,02348275 0,1042426 ! female gamete generation GO:0007292 61 41 1,000 0,02348275 0,10405062 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,02348275 0,10385935 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02456469 0,1084452 GO:0090047|positive regulation of transcription regulator activity, ! regulation of tube size GO:0035150 71 42 1,000 0,02456469 0,10824658 GO:0050880|regulation of blood vessel size, ! epithelial cell differentiation GO:0030855 79 43 1,000 0,02566668 0,11289584 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 0,02566668 0,11268982 ! double-strand break repair GO:0006302 81 44 1,000 0,02678845 0,11740076 ! B cell differentiation GO:0030183 107 44 1,000 0,02678845 0,1171873 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,02678845 0,11697462 ! developmental growth GO:0048589 82 44 1,000 0,02678845 0,11676271 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,02792975 0,12151714 ! leukocyte migration GO:0050900 68 45 1,000 0,02792975 0,1212978 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,02792975 0,12107924 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 0,02792975 0,12086147 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02855735 0,12335543 ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02855735 0,12313436 ! neuron fate determination GO:0048664 7 5 0,000 0,02855735 0,12291408 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02855735 0,1226946 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02855735 0,12247589 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02855735 0,12225796 ! polyol transport GO:0015791 12 5 0,000 0,02855735 0,12204081 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02855735 0,12182442 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02855735 0,1216088 ! response to superoxide GO:0000303 10 5 0,000 0,02855735 0,12139395 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02855735 0,12117985 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02855735 0,1209665 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02855735 0,12075391 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02855735 0,12054206 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02855735 0,12033095 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02855735 0,12012058 ! cobalt ion transport GO:0006824 11 5 0,000 0,02855735 0,11991095 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02855735 0,11970204 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02855735 0,11949387 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02855735 0,11928641 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02855735 0,11907968 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02855735 0,11887366 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02855735 0,11866835 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02855735 0,11846375 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02855735 0,11825985 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02855735 0,11805666 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02855735 0,11785416 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02855735 0,11765235 ! negative chemotaxis GO:0050919 14 5 0,000 0,02855735 0,11745124 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02855735 0,11725081 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02855735 0,11705106 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02855735 0,116852 ! behavioral response to pain GO:0048266 9 5 0,000 0,02855735 0,1166536 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02855735 0,11645589 ! Notch receptor processing GO:0007220 8 5 0,000 0,02855735 0,11625884 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02855735 0,11606245 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02855735 0,11586673 ! micturition GO:0060073 9 5 0,000 0,02855735 0,11567167 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02855735 0,11547727 ! copulation GO:0007620 9 5 0,000 0,02855735 0,11528351 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02855735 0,11509041 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02855735 0,11489795 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02855735 0,11470613 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02855735 0,11451496 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02855735 0,11432441 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02855735 0,11413451 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02855735 0,11394523 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02855735 0,11375658 ! grooming behavior GO:0007625 6 5 0,000 0,02855735 0,11356855 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02855735 0,11338114 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02855735 0,11319435 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02855735 0,11300818 ! response to protozoan GO:0001562 10 5 0,000 0,02855735 0,11282262 ! lymph vessel development GO:0001945 10 5 0,000 0,02855735 0,11263766 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02855735 0,11245331 ! endochondral ossification GO:0001958 16 5 0,000 0,02855735 0,11226956 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02855735 0,11208642 ! parathyroid gland development GO:0060017 13 5 0,000 0,02855735 0,11190387 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02855735 0,11172191 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02855735 0,11154054 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02855735 0,11135976 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02855735 0,11117957 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02855735 0,11099996 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02855735 0,11082092 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02855735 0,11064247 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02855735 0,11046459 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02855735 0,11028728 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02855735 0,11011053 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02855735 0,10993436 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02855735 0,10975874 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02855735 0,10958369 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02855735 0,10940919 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02855735 0,10923525 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02855735 0,10906186 ! histidine catabolic process GO:0006548 6 5 0,000 0,02855735 0,10888902 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02855735 0,10871673 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02855735 0,10854498 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02855735 0,10837377 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02855735 0,10820311 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02855735 0,10803298 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02855735 0,10786338 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02855735 0,10769432 ! polyol catabolic process GO:0046174 7 5 0,000 0,02855735 0,10752578 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02855735 0,10735777 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02855735 0,10719029 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02855735 0,10702332 ! mitochondrial fission GO:0000266 8 5 0,000 0,02855735 0,10685688 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02855735 0,10669095 ! mRNA transcription GO:0009299 9 5 0,000 0,02855735 0,10652554 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02855735 0,10636064 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02855735 0,10619625 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02855735 0,10603237 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02855735 0,10586899 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02855735 0,10570611 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02855735 0,10554374 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02855735 0,10538186 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02855735 0,10522048 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02855735 0,10505959 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02855735 0,1048992 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02855735 0,10473929 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02855735 0,10457987 ! forebrain neuron development GO:0021884 13 5 0,000 0,02855735 0,10442093 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02855735 0,10426248 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02855735 0,1041045 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02855735 0,10394701 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02855735 0,10378999 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02855735 0,10363344 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02855735 0,10347737 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02855735 0,10332176 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02855735 0,10316663 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02855735 0,10301195 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02855735 0,10285774 ! basic amino acid transport GO:0015802 11 5 0,000 0,02855735 0,102704 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02855735 0,10255071 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02855735 0,10239787 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02855735 0,1022455 ! depyrimidination GO:0045008 10 5 0,000 0,02855735 0,10209357 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02855735 0,1019421 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02855735 0,10179107 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02855735 0,10164049 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02855735 0,10149036 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02855735 0,10134067 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02855735 0,10119142 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02855735 0,10104261 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02855735 0,10089423 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02855735 0,1007463 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02855735 0,10059879 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02855735 0,10045172 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02855735 0,10030507 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02855735 0,10015885 ! response to arsenic GO:0046685 10 5 0,000 0,02855735 0,10001306 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02855735 0,09986769 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02855735 0,09972275 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02855735 0,09957822 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02855735 0,09943411 ! response to cadmium ion GO:0046686 7 5 0,000 0,02855735 0,09929042 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02855735 0,09914715 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02855735 0,09900428 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02855735 0,09886183 ! decidualization GO:0046697 11 5 0,000 0,02855735 0,09871979 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02855735 0,09857815 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02855735 0,09843692 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02855735 0,0982961 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02855735 0,09815568 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02855735 0,09801565 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02855735 0,09787603 ! neural tube patterning GO:0021532 7 5 0,000 0,02855735 0,0977368 ! embryonic cleavage GO:0040016 6 5 0,000 0,02855735 0,09759797 ! peroxisome fission GO:0016559 5 5 0,000 0,02855735 0,09745954 ! histone demethylation GO:0016577 10 5 0,000 0,02855735 0,09732149 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02855735 0,09718384 ! mitotic recombination GO:0006312 9 5 0,000 0,02855735 0,09704657 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02855735 0,09690969 ! metaphase plate congression GO:0051310 7 5 0,000 0,02855735 0,0967732 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02855735 0,09663709 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02855735 0,09650137 ! enteric nervous system development GO:0048484 8 5 0,000 0,02855735 0,09636602 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02855735 0,09623106 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02855735 0,09609647 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02855735 0,09596225 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02855735 0,09582841 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02855735 0,09569495 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02855735 0,09556185 ! plasminogen activation GO:0031639 5 5 0,000 0,02855735 0,09542913 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02855735 0,09529677 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02855735 0,09516478 ! metaphase GO:0051323 8 5 0,000 0,02855735 0,09503316 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02855735 0,0949019 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02855735 0,094771 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02855735 0,09464046 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02855735 0,09451028 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02855735 0,09438046 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02855735 0,09425099 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02855735 0,09412188 ! response to redox state GO:0051775 5 5 0,000 0,02855735 0,09399312 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02855735 0,09386472 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02855735 0,09373666 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02855735 0,09360896 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02855735 0,0934816 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02855735 0,09335458 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02855735 0,09322791 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02855735 0,09310159 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02855735 0,09297561 ! striatum development GO:0021756 9 5 0,000 0,02855735 0,09284996 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02855735 0,09272466 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02855735 0,09259969 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02855735 0,09247506 ! glial cell migration GO:0008347 11 5 0,000 0,02855735 0,09235077 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02855735 0,09222681 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02855735 0,09210318 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02855735 0,09197988 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02855735 0,09185692 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02855735 0,09173428 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02855735 0,09161196 ! neuroprotection GO:0043526 6 5 0,000 0,02855735 0,09148998 ! neural plate development GO:0001840 8 5 0,000 0,02855735 0,09136832 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02855735 0,09124698 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02855735 0,09112596 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02855735 0,09100526 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02855735 0,09088489 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02855735 0,09076483 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02855735 0,09064508 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02855735 0,09052566 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02855735 0,09040654 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02855735 0,09028774 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02855735 0,09016926 ! spindle assembly GO:0051225 6 5 0,000 0,02855735 0,09005108 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02855735 0,08993321 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02855735 0,08981565 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02855735 0,0896984 ! drug metabolic process GO:0017144 6 5 0,000 0,02855735 0,08958145 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02855735 0,08946481 ! organ regeneration GO:0031100 7 5 0,000 0,02855735 0,08934847 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02855735 0,08923243 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02855735 0,0891167 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02855735 0,08900126 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,02909031 0,09054501 ! response to calcium ion GO:0051592 81 47 1,000 0,03026988 0,09409473 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,03026988 0,09397332 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,03026988 0,09385222 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,03026988 0,09373143 ! mitochondrial transport GO:0006839 82 48 1,000 0,03146819 0,0973168 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,03146819 0,09719187 ! regulation of action potential GO:0001508 95 49 1,000 0,032685 0,10082066 ! induction of apoptosis by extracellular signals GO:0008624 89 49 1,000 0,032685 0,10069157 ! response to temperature stimulus GO:0009266 76 49 1,000 0,032685 0,1005628 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,032685 0,10043437 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 0,032685 0,10030627 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 1,000 0,032685 0,10017849 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,032685 0,10005103 ! histone modification GO:0016570 91 50 1,000 0,03392006 0,10369969 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03417076 0,10433355 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03417076 0,10420132 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03417076 0,10406942 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03417076 0,10393785 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03417076 0,10380662 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03417076 0,10367571 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03417076 0,10354514 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03417076 0,10341489 ! sleep GO:0030431 13 6 0,000 0,03417076 0,10328497 ! response to oxygen radical GO:0000305 11 6 0,000 0,03417076 0,10315538 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03417076 0,10302611 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03417076 0,10289717 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03417076 0,10276855 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03417076 0,10264025 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03417076 0,10251227 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03417076 0,10238461 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03417076 0,10225726 ! forebrain regionalization GO:0021871 8 6 0,000 0,03417076 0,10213024 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03417076 0,10200352 ! male meiosis GO:0007140 7 6 0,000 0,03417076 0,10187712 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03417076 0,10175104 ! response to zinc ion GO:0010043 9 6 0,000 0,03417076 0,10162526 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03417076 0,1014998 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03417076 0,10137465 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03417076 0,1012498 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03417076 0,10112526 ! malate metabolic process GO:0006108 11 6 0,000 0,03417076 0,10100103 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03417076 0,1008771 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03417076 0,10075348 ! protein refolding GO:0042026 15 6 0,000 0,03417076 0,10063016 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03417076 0,10050714 ! opsonization GO:0008228 8 6 0,000 0,03417076 0,10038442 ! mating behavior GO:0007617 7 6 0,000 0,03417076 0,100262 ! neuron remodeling GO:0016322 15 6 0,000 0,03417076 0,10013988 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03417076 0,10001805 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03417076 0,09989652 ! equilibrioception GO:0050957 14 6 0,000 0,03417076 0,09977529 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03417076 0,09965435 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03417076 0,0995337 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03417076 0,09941335 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03417076 0,09929328 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03417076 0,09917351 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03417076 0,09905402 ! toxin metabolic process GO:0009404 11 6 0,000 0,03417076 0,09893482 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03417076 0,09881591 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03417076 0,09869729 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03417076 0,09857894 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03417076 0,09846089 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03417076 0,09834311 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03417076 0,09822561 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03417076 0,0981084 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03417076 0,09799147 ! thymic T cell selection GO:0045061 12 6 0,000 0,03417076 0,09787481 ! protein lipoylation GO:0009249 10 6 0,000 0,03417076 0,09775843 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03417076 0,09764233 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03417076 0,0975265 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03417076 0,09741095 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03417076 0,09729567 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03417076 0,09718066 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03417076 0,09706593 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03417076 0,09695146 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03417076 0,09683727 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03417076 0,09672334 ! hyperosmotic response GO:0006972 9 6 0,000 0,03417076 0,09660968 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03417076 0,09649629 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03417076 0,09638316 ! urea metabolic process GO:0019627 7 6 0,000 0,03417076 0,0962703 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03417076 0,09615771 ! neutrophil activation GO:0042119 8 6 0,000 0,03417076 0,09604537 ! regulation of appetite GO:0032098 9 6 0,000 0,03417076 0,0959333 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03417076 0,09582149 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03417076 0,09570994 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03417076 0,09559865 ! nucleoside salvage GO:0043174 9 6 0,000 0,03417076 0,09548762 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03417076 0,09537684 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03417076 0,09526633 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03417076 0,09515606 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,03417076 0,09504606 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03417076 0,0949363 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03417076 0,0948268 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03417076 0,09471756 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03417076 0,09460856 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03417076 0,09449982 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03417076 0,09439132 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03417076 0,09428307 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03417076 0,09417507 ! establishment of spindle localization GO:0051293 12 6 0,000 0,03417076 0,09406732 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03417076 0,09395982 ! monocyte differentiation GO:0030224 12 6 0,000 0,03417076 0,09385256 ! neural nucleus development GO:0048857 14 6 0,000 0,03417076 0,09374554 ! response to UV-C GO:0010225 11 6 0,000 0,03417076 0,09363877 ! astrocyte development GO:0014002 15 6 0,000 0,03417076 0,09353224 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03417076 0,09342595 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03417076 0,09331991 ! interaction with symbiont GO:0051702 13 6 0,000 0,03417076 0,0932141 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03417076 0,09310854 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03417076 0,09300321 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03417076 0,09289812 ! response to copper ion GO:0046688 10 6 0,000 0,03417076 0,09279327 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03417076 0,09268866 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03417076 0,09258428 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03417076 0,09248013 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03417076 0,09237622 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03417076 0,09227255 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03417076 0,0921691 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03417076 0,09206589 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03417076 0,09196291 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03417076 0,09186016 ! Schwann cell development GO:0014044 15 6 0,000 0,03417076 0,09175763 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03417076 0,09165534 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03417076 0,09155327 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03417076 0,09145143 ! subpallium development GO:0021544 10 6 0,000 0,03417076 0,09134982 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03417076 0,09124843 ! histone ubiquitination GO:0016574 8 6 0,000 0,03417076 0,09114727 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03417076 0,09104633 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03417076 0,09094562 ! G2 phase GO:0051319 16 6 0,000 0,03417076 0,09084513 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03417076 0,09074486 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03417076 0,09064481 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03417076 0,09054498 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03417076 0,09044537 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03417076 0,09034598 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03417076 0,0902468 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03417076 0,09014785 ! receptor internalization GO:0031623 10 6 0,000 0,03417076 0,09004911 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03417076 0,08995059 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03417076 0,08985228 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03417076 0,08975419 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03417076 0,08965631 ! protein deubiquitination GO:0016579 14 6 0,000 0,03417076 0,08955865 ! protein destabilization GO:0031648 9 6 0,000 0,03417076 0,0894612 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03417076 0,08936396 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03417076 0,08926693 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03417076 0,08917011 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03417076 0,0890735 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03417076 0,0889771 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03417076 0,08888091 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03417076 0,08878492 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03417076 0,08868915 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03417076 0,08859358 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03417076 0,08849821 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03417076 0,08840305 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03417076 0,0883081 ! catecholamine transport GO:0051937 9 6 0,000 0,03417076 0,08821335 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03417076 0,0881188 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03417076 0,08802445 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03417076 0,08793031 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03417076 0,08783637 ! maternal placenta development GO:0001893 12 6 0,000 0,03417076 0,08774262 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03417076 0,08764908 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03417076 0,08755574 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03417076 0,0874626 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03417076 0,08736965 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03417076 0,0872769 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03417076 0,08718435 ! positive regulation of binding GO:0051099 78 51 1,000 0,03517311 0,08964671 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,03517311 0,08955184 ! excretion GO:0007588 83 51 1,000 0,03517311 0,08945718 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 1,000 0,03517311 0,08936272 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,03517311 0,08926845 ! vesicle organization GO:0016050 107 51 1,000 0,03517311 0,08917439 ! regulation of cell shape GO:0008360 125 51 1,000 0,03517311 0,08908052 ! regulation of muscle contraction GO:0006937 81 52 1,000 0,03644391 0,09220193 ! covalent chromatin modification GO:0016569 101 52 1,000 0,03644391 0,09210508 ! synapse organization GO:0050808 85 52 1,000 0,03644391 0,09200843 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 1,000 0,03773221 0,09516111 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,03773221 0,09506146 ! cell maturation GO:0048469 100 53 1,000 0,03773221 0,09496203 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,03773221 0,0948628 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,03903778 0,09804269 ! tRNA transcription GO:0009304 14 7 0,000 0,03975192 0,09973213 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03975192 0,09962824 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03975192 0,09952457 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03975192 0,09942111 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03975192 0,09931787 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03975192 0,09921484 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03975192 0,09911203 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03975192 0,09900943 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03975192 0,09890704 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03975192 0,09880486 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03975192 0,0987029 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03975192 0,09860114 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03975192 0,0984996 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03975192 0,09839826 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03975192 0,09829713 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03975192 0,09819621 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,03975192 0,0980955 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03975192 0,09799499 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03975192 0,09789469 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03975192 0,09779459 ! glycolipid transport GO:0046836 10 7 0,000 0,03975192 0,0976947 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03975192 0,09759501 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03975192 0,09749552 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03975192 0,09739624 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03975192 0,09729716 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03975192 0,09719828 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03975192 0,0970996 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03975192 0,09700112 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03975192 0,09690285 ! mRNA stabilization GO:0048255 18 7 0,000 0,03975192 0,09680477 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,03975192 0,09670688 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03975192 0,0966092 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03975192 0,09651171 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03975192 0,09641442 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03975192 0,09631733 ! lipoprotein transport GO:0042953 14 7 0,000 0,03975192 0,09622043 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03975192 0,09612373 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03975192 0,09602722 ! rhythmic behavior GO:0007622 15 7 0,000 0,03975192 0,0959309 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03975192 0,09583478 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03975192 0,09573885 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03975192 0,09564311 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03975192 0,09554756 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03975192 0,0954522 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03975192 0,09535704 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03975192 0,09526206 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03975192 0,09516727 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03975192 0,09507267 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03975192 0,09497826 GO:0045911|positive regulation of DNA recombination, ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03975192 0,09488404 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03975192 0,09479 ! spinal cord patterning GO:0021511 13 7 0,000 0,03975192 0,09469615 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03975192 0,09460248 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03975192 0,094509 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03975192 0,0944157 ! adrenal gland development GO:0030325 17 7 0,000 0,03975192 0,09432259 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03975192 0,09422966 ! ovulation GO:0030728 9 7 0,000 0,03975192 0,09413692 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03975192 0,09404435 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03975192 0,09395197 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03975192 0,09385977 ! microtubule nucleation GO:0007020 20 7 0,000 0,03975192 0,09376775 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03975192 0,09367591 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03975192 0,09358426 ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03975192 0,09349277 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03975192 0,09340147 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03975192 0,09331035 ! galactose metabolic process GO:0006012 13 7 0,000 0,03975192 0,0932194 ! vesicle fusion GO:0006906 17 7 0,000 0,03975192 0,09312864 ! response to dietary excess GO:0002021 8 7 0,000 0,03975192 0,09303804 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03975192 0,09294763 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03975192 0,09285739 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03975192 0,09276732 GO:0046464|acylglycerol catabolic process, ! organ growth GO:0035265 15 7 0,000 0,03975192 0,09267743 ! purine salvage GO:0043101 10 7 0,000 0,03975192 0,09258771 ! nucleoside transport GO:0015858 8 7 0,000 0,03975192 0,09249817 ! parturition GO:0007567 14 7 0,000 0,03975192 0,0924088 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03975192 0,0923196 ! rRNA modification GO:0000154 14 7 0,000 0,03975192 0,09223058 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03975192 0,09214172 ! spindle checkpoint GO:0031577 15 7 0,000 0,03975192 0,09205304 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03975192 0,09196453 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03975192 0,09187619 ! macrophage differentiation GO:0030225 11 7 0,000 0,03975192 0,09178801 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03975192 0,09170001 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03975192 0,09161217 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03975192 0,09152451 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03975192 0,09143701 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03975192 0,09134967 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,03975192 0,09126251 ! eating behavior GO:0042755 7 7 0,000 0,03975192 0,09117551 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03975192 0,09108867 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03975192 0,09100201 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03975192 0,0909155 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03975192 0,09082916 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03975192 0,09074299 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03975192 0,09065698 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03975192 0,09057113 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03975192 0,09048544 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03975192 0,09039991 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03975192 0,09031455 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03975192 0,09022935 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03975192 0,09014431 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03975192 0,09005942 ! regulation of meiosis GO:0040020 12 7 0,000 0,03975192 0,0899747 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03975192 0,08989014 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03975192 0,08980574 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03975192 0,08972149 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03975192 0,0896374 ! transcription termination GO:0006353 13 7 0,000 0,03975192 0,08955347 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03975192 0,0894697 ! anaphase GO:0051322 17 7 0,000 0,03975192 0,08938608 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03975192 0,08930262 ! axonal fasciculation GO:0007413 18 7 0,000 0,03975192 0,08921932 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03975192 0,08913617 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03975192 0,08905317 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03975192 0,08897033 ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03975192 0,08888765 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03975192 0,08880511 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03975192 0,08872274 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03975192 0,08864051 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03975192 0,08855843 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03975192 0,08847651 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03975192 0,08839474 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03975192 0,08831312 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03975192 0,08823165 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03975192 0,08815033 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03975192 0,08806916 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03975192 0,08798814 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03975192 0,08790727 ! lymph node development GO:0048535 10 7 0,000 0,03975192 0,08782655 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03975192 0,08774597 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03975192 0,08766554 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03975192 0,08758526 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03975192 0,08750513 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03975192 0,08742515 ! adult feeding behavior GO:0008343 9 7 0,000 0,03975192 0,0873453 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03975192 0,08726561 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03975192 0,08718606 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03975192 0,08710666 ! muscle adaptation GO:0043500 14 7 0,000 0,03975192 0,0870274 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03975192 0,08694828 ! retina homeostasis GO:0001895 12 7 0,000 0,03975192 0,08686931 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03975192 0,08679048 ! protein prenylation GO:0018342 18 7 0,000 0,03975192 0,08671179 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03975192 0,08663325 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03975192 0,08655485 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03975192 0,08647659 ! RNA elongation GO:0006354 79 55 1,000 0,04036037 0,08772091 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,04036037 0,08764174 ! regulation of actin filament length GO:0030832 105 56 1,000 0,04169974 0,09046851 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,04169974 0,09038701 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,04169974 0,09030565 ! muscle fiber development GO:0048747 112 57 1,000 0,04305567 0,09315822 ! lipid modification GO:0030258 97 57 1,000 0,04305567 0,09307452 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04530101 0,09784042 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04530101 0,09775267 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04530101 0,09766508 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04530101 0,09757764 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04530101 0,09749036 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04530101 0,09740324 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04530101 0,09731627 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04530101 0,09722946 ! meiotic prophase I GO:0007128 13 8 0,000 0,04530101 0,0971428 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04530101 0,0970563 ! oligopeptide transport GO:0006857 15 8 0,000 0,04530101 0,09696995 ! UTP metabolic process GO:0046051 8 8 0,000 0,04530101 0,09688376 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04530101 0,09679771 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04530101 0,09671182 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04530101 0,09662609 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04530101 0,0965405 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04530101 0,09645507 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04530101 0,09636978 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04530101 0,09628465 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04530101 0,09619967 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04530101 0,09611484 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04530101 0,09603015 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04530101 0,09594562 ! reflex GO:0060004 16 8 0,000 0,04530101 0,09586124 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04530101 0,095777 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04530101 0,09569291 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04530101 0,09560897 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04530101 0,09552517 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04530101 0,09544153 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04530101 0,09535803 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04530101 0,09527467 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04530101 0,09519146 ! histidine metabolic process GO:0006547 16 8 0,000 0,04530101 0,0951084 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04530101 0,09502548 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04530101 0,0949427 ! glycine catabolic process GO:0006546 13 8 0,000 0,04530101 0,09486007 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04530101 0,09477759 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04530101 0,09469524 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04530101 0,09461304 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04530101 0,09453098 ! melanin metabolic process GO:0006582 15 8 0,000 0,04530101 0,09444907 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04530101 0,09436729 ! macrophage activation GO:0042116 12 8 0,000 0,04530101 0,09428566 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04530101 0,09420417 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04530101 0,09412282 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04530101 0,09404161 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04530101 0,09396054 ! osteoblast development GO:0002076 16 8 0,000 0,04530101 0,09387961 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04530101 0,09379882 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04530101 0,09371816 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04530101 0,09363765 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04530101 0,09355727 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04530101 0,09347704 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04530101 0,09339694 ! response to UV-B GO:0010224 16 8 0,000 0,04530101 0,09331697 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04530101 0,09323715 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04530101 0,09315746 ! intermediate filament organization GO:0045109 12 8 0,000 0,04530101 0,0930779 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04530101 0,09299849 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04530101 0,0929192 ! cellular extravasation GO:0045123 12 8 0,000 0,04530101 0,09284005 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04530101 0,09276104 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04530101 0,09268216 ! response to antibiotic GO:0046677 11 8 0,000 0,04530101 0,09260342 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04530101 0,09252481 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04530101 0,09244633 ! DNA topological change GO:0006265 12 8 0,000 0,04530101 0,09236799 ! response to tropane GO:0014073 15 8 0,000 0,04530101 0,09228978 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04530101 0,0922117 ! melanosome transport GO:0032402 13 8 0,000 0,04530101 0,09213375 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04530101 0,09205593 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04530101 0,09197825 ! mast cell activation GO:0045576 14 8 0,000 0,04530101 0,0919007 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04530101 0,09182327 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04530101 0,09174598 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04530101 0,09166882 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04530101 0,09159179 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04530101 0,09151488 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04530101 0,09143811 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04530101 0,09136146 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04530101 0,09128495 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04530101 0,09120856 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04530101 0,09113229 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04530101 0,09105616 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04530101 0,09098015 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04530101 0,09090427 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04530101 0,09082852 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04530101 0,09075289 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04530101 0,09067739 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04530101 0,09060202 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04530101 0,09052676 ! hormone catabolic process GO:0042447 17 8 0,000 0,04530101 0,09045164 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04530101 0,09037664 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04530101 0,09030176 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04530101 0,09022701 ! ATP catabolic process GO:0006200 11 8 0,000 0,04530101 0,09015238 ! blastocyst growth GO:0001832 19 8 0,000 0,04530101 0,09007787 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04530101 0,09000349 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04530101 0,08992923 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04530101 0,08985509 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04530101 0,08978107 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04530101 0,08970718 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04530101 0,08963341 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04530101 0,08955976 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04530101 0,08948623 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04530101 0,08941282 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04530101 0,08933953 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04530101 0,08926636 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04530101 0,08919331 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04530101 0,08912038 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04530101 0,08904757 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04530101 0,08897488 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04530101 0,0889023 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04530101 0,08882985 ! regulation of cellular component size GO:0032535 109 59 1,000 0,04581623 0,08976699 ! establishment of organelle localization GO:0051656 109 59 1,000 0,04581623 0,08969394 ! regulation of heart contraction GO:0008016 110 60 1,000 0,04722041 0,09236774 ! viral reproductive process GO:0022415 126 62 1,000 0,05007543 0,09787286 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,05007543 0,09779342 ! axon extension GO:0048675 15 9 0,000 0,05081822 0,09916353 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05081822 0,09908317 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05081822 0,09900294 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05081822 0,09892284 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05081822 0,09884287 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05081822 0,09876303 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05081822 0,09868332 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05081822 0,09860373 ! phosphate transport GO:0006817 19 9 0,000 0,05081822 0,09852428 ! reproductive behavior GO:0019098 19 9 0,000 0,05081822 0,09844495 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05081822 0,09836575 ! CTP metabolic process GO:0046036 9 9 0,000 0,05081822 0,09828668 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05081822 0,09820773 ! GTP metabolic process GO:0046039 9 9 0,000 0,05081822 0,09812891 ! RNA methylation GO:0001510 15 9 0,000 0,05081822 0,09805022 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05081822 0,09797166 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,05081822 0,09789322 ! artery development GO:0060840 24 9 0,000 0,05081822 0,0978149 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05081822 0,09773671 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05081822 0,09765865 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05081822 0,09758071 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05081822 0,09750289 ! chemosensory behavior GO:0007635 20 9 0,000 0,05081822 0,0974252 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05081822 0,09734763 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05081822 0,09727019 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05081822 0,09719287 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05081822 0,09711567 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05081822 0,09703859 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05081822 0,09696164 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05081822 0,09688481 ! protein targeting to ER GO:0045047 22 9 0,000 0,05081822 0,0968081 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05081822 0,09673151 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05081822 0,09665504 ! T cell selection GO:0045058 23 9 0,000 0,05081822 0,09657869 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05081822 0,09650247 ! endosome organization GO:0007032 17 9 0,000 0,05081822 0,09642636 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05081822 0,09635038 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05081822 0,09627451 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05081822 0,09619876 ! mannose metabolic process GO:0006013 13 9 0,000 0,05081822 0,09612314 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05081822 0,09604763 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05081822 0,09597224 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05081822 0,09589696 ! receptor clustering GO:0043113 18 9 0,000 0,05081822 0,09582181 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05081822 0,09574677 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05081822 0,09567185 ! ruffle organization GO:0031529 15 9 0,000 0,05081822 0,09559705 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05081822 0,09552237 ! behavioral fear response GO:0001662 22 9 0,000 0,05081822 0,0954478 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05081822 0,09537334 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05081822 0,09529901 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05081822 0,09522479 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,05081822 0,09515068 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,05081822 0,09507669 ! segment specification GO:0007379 13 9 0,000 0,05081822 0,09500282 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05081822 0,09492906 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05081822 0,09485541 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05081822 0,09478188 ! response to amine stimulus GO:0014075 13 9 0,000 0,05081822 0,09470846 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05081822 0,09463516 ! erythrocyte development GO:0048821 15 9 0,000 0,05081822 0,09456197 ! gas homeostasis GO:0033483 16 9 0,000 0,05081822 0,09448889 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05081822 0,09441593 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,05081822 0,09434308 ! postreplication repair GO:0006301 22 9 0,000 0,05081822 0,09427034 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05081822 0,09419771 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05081822 0,09412519 ! icosanoid secretion GO:0032309 15 9 0,000 0,05081822 0,09405279 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05081822 0,0939805 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05081822 0,09390832 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05081822 0,09383625 ! regulation of cell division GO:0051302 15 9 0,000 0,05081822 0,09376429 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05081822 0,09369244 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05081822 0,0936207 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05081822 0,09354906 ! sterol catabolic process GO:0016127 11 9 0,000 0,05081822 0,09347754 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05081822 0,09340613 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05081822 0,09333483 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05081822 0,09326364 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05081822 0,09319255 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,05081822 0,09312157 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,05081822 0,09305071 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05081822 0,09297995 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05081822 0,09290929 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05081822 0,09283875 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05081822 0,09276831 ! purine base metabolic process GO:0006144 21 9 0,000 0,05081822 0,09269797 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05081822 0,09262775 ! pigment granule transport GO:0051904 17 9 0,000 0,05081822 0,09255763 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05081822 0,09248762 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05081822 0,09241771 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05081822 0,09234791 ! mitochondrion localization GO:0051646 15 9 0,000 0,05081822 0,09227821 ! nucleoside monophosphate metabolic process GO:0009123 107 63 1,000 0,05152583 0,09349256 ! detection of external stimulus GO:0009581 91 63 1,000 0,05152583 0,09342211 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,05299118 0,0960066 ! actin filament organization GO:0007015 148 66 1,000 0,05596588 0,10131972 ! secondary metabolic process GO:0019748 116 66 1,000 0,05596588 0,10124354 ! cell projection assembly GO:0030031 120 66 1,000 0,05596588 0,10116747 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05630372 0,10170177 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05630372 0,10162547 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05630372 0,10154929 ! synapsis GO:0007129 13 10 0,000 0,05630372 0,10147323 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05630372 0,10139727 ! N-glycan processing GO:0006491 20 10 0,000 0,05630372 0,10132143 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05630372 0,10124571 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,05630372 0,10117009 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05630372 0,10109459 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05630372 0,10101921 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05630372 0,10094393 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05630372 0,10086877 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05630372 0,10079372 ! androgen metabolic process GO:0008209 17 10 0,000 0,05630372 0,10071878 ! phospholipid efflux GO:0033700 16 10 0,000 0,05630372 0,10064395 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05630372 0,10056923 ! lung alveolus development GO:0048286 26 10 0,000 0,05630372 0,10049463 ! pathogenesis GO:0009405 13 10 0,000 0,05630372 0,10042013 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05630372 0,10034575 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05630372 0,10027147 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,05630372 0,10019731 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05630372 0,10012325 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,05630372 0,1000493 ! endoderm development GO:0007492 16 10 0,000 0,05630372 0,09997547 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05630372 0,09990174 ! arginine catabolic process GO:0006527 13 10 0,000 0,05630372 0,09982812 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05630372 0,09975461 ! proline metabolic process GO:0006560 13 10 0,000 0,05630372 0,0996812 ! L-serine metabolic process GO:0006563 18 10 0,000 0,05630372 0,09960791 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05630372 0,09953472 ! V(D)J recombination GO:0033151 28 10 0,000 0,05630372 0,09946164 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05630372 0,09938867 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05630372 0,0993158 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05630372 0,09924304 ! B cell proliferation GO:0042100 18 10 0,000 0,05630372 0,09917039 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05630372 0,09909785 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05630372 0,09902541 ! multicellular organism growth GO:0035264 18 10 0,000 0,05630372 0,09895307 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05630372 0,09888084 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05630372 0,09880872 ! epithelial cell development GO:0002064 20 10 0,000 0,05630372 0,0987367 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05630372 0,09866479 ! macroautophagy GO:0016236 17 10 0,000 0,05630372 0,09859298 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05630372 0,09852128 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05630372 0,09844968 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05630372 0,09837818 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05630372 0,09830679 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05630372 0,0982355 ! brain morphogenesis GO:0048854 23 10 0,000 0,05630372 0,09816432 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,05630372 0,09809323 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05630372 0,09802226 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05630372 0,09795138 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,05630372 0,0978806 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05630372 0,09780993 ! response to dsRNA GO:0043331 20 10 0,000 0,05630372 0,09773936 ! DNA ligation GO:0006266 19 10 0,000 0,05630372 0,09766889 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05630372 0,09759853 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05630372 0,09752826 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05630372 0,0974581 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05630372 0,09738803 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05630372 0,09731807 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05630372 0,09724821 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05630372 0,09717845 ! mRNA cleavage GO:0006379 17 10 0,000 0,05630372 0,09710879 ! protein sumoylation GO:0016925 15 10 0,000 0,05630372 0,09703922 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05630372 0,09696976 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05630372 0,0969004 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05630372 0,09683113 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05630372 0,09676197 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05630372 0,0966929 ! salivary gland development GO:0007431 27 10 0,000 0,05630372 0,09662393 ! prophase GO:0051324 15 10 0,000 0,05630372 0,09655507 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05630372 0,09648629 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05630372 0,09641762 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05630372 0,09634904 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,05630372 0,09628057 ! midbrain development GO:0030901 13 10 0,000 0,05630372 0,09621218 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05630372 0,0961439 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05630372 0,09607571 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05630372 0,09600762 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05630372 0,09593963 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05630372 0,09587173 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05630372 0,09580393 ! detection of calcium ion GO:0005513 23 10 0,000 0,05630372 0,09573622 ! blastocyst formation GO:0001825 17 10 0,000 0,05630372 0,09566861 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05630372 0,0956011 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05630372 0,09553368 ! activation of innate immune response GO:0002218 12 10 0,000 0,05630372 0,09546635 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05630372 0,09539912 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05630372 0,09533199 ! response to nicotine GO:0035094 20 10 0,000 0,05630372 0,09526495 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05630372 0,095198 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05630372 0,09513115 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05630372 0,09506439 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,0574748 0,09697361 ! adaptive immune response GO:0002250 119 67 1,000 0,0574748 0,09690566 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,05899782 0,09940388 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 1,000 0,05899782 0,09933432 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,06175771 0,10390842 ! respiratory burst GO:0045730 17 11 0,000 0,06175771 0,10383581 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06175771 0,1037633 ! neuron fate specification GO:0048665 17 11 0,000 0,06175771 0,10369089 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06175771 0,10361858 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06175771 0,10354637 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06175771 0,10347427 ! thyroid gland development GO:0030878 26 11 0,000 0,06175771 0,10340226 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06175771 0,10333035 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06175771 0,10325855 ! response to pain GO:0048265 24 11 0,000 0,06175771 0,10318684 ! T cell proliferation GO:0042098 26 11 0,000 0,06175771 0,10311523 ! blood vessel remodeling GO:0001974 29 11 0,000 0,06175771 0,10304372 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,06175771 0,10297231 ! bone resorption GO:0045453 16 11 0,000 0,06175771 0,102901 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06175771 0,10282979 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06175771 0,10275868 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06175771 0,10268766 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06175771 0,10261674 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06175771 0,10254593 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06175771 0,1024752 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06175771 0,10240458 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06175771 0,10233405 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,06175771 0,10226362 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06175771 0,10219329 ! UV protection GO:0009650 19 11 0,000 0,06175771 0,10212306 ! adult heart development GO:0007512 14 11 0,000 0,06175771 0,10205292 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,06175771 0,10198287 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06175771 0,10191293 ! temperature homeostasis GO:0001659 17 11 0,000 0,06175771 0,10184307 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06175771 0,10177332 ! negative regulation of ossification GO:0030279 26 11 0,000 0,06175771 0,10170366 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,06175771 0,10163409 ! regulation of organ growth GO:0046620 13 11 0,000 0,06175771 0,10156463 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06175771 0,10149525 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06175771 0,10142597 ! embryonic axis specification GO:0000578 18 11 0,000 0,06175771 0,10135678 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06175771 0,10128769 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06175771 0,1012187 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06175771 0,10114979 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06175771 0,10108098 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,06175771 0,10101227 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06175771 0,10094365 ! zymogen activation GO:0031638 15 11 0,000 0,06175771 0,10087512 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06175771 0,10080668 ! nucleosome positioning GO:0016584 15 11 0,000 0,06175771 0,10073834 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06175771 0,10067009 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06175771 0,10060193 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06175771 0,10053386 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,06175771 0,10046589 ! acid secretion GO:0046717 18 11 0,000 0,06175771 0,100398 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06175771 0,10033021 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06175771 0,10026251 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06175771 0,10019491 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06175771 0,10012739 ! thymus development GO:0048538 27 11 0,000 0,06175771 0,10005996 ! cholesterol efflux GO:0033344 19 11 0,000 0,06175771 0,09999263 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06175771 0,09992538 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06175771 0,09985823 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,06175771 0,09979117 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,06175771 0,09972419 ! embryonic gut development GO:0048566 15 11 0,000 0,06175771 0,09965731 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06175771 0,09959051 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06175771 0,09952381 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06175771 0,09945719 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06175771 0,09939067 ! defense response to fungus GO:0050832 13 11 0,000 0,06175771 0,09932423 ! developmental induction GO:0031128 19 11 0,000 0,06175771 0,09925788 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,06175771 0,09919162 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06175771 0,09912545 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06175771 0,09905936 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06175771 0,09899337 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06175771 0,09892746 ! nucleus localization GO:0051647 19 11 0,000 0,06175771 0,09886164 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06175771 0,09879591 ! humoral immune response GO:0006959 109 71 1,000 0,06364933 0,10175435 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,06364933 0,10168678 ! regulation of immune effector process GO:0002697 137 71 1,000 0,06364933 0,10161931 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,06522664 0,10406849 ! learning or memory GO:0007611 147 73 1,000 0,066817 0,10653525 ! regulation of blood pressure GO:0008217 125 73 1,000 0,066817 0,1064647 ! axon guidance GO:0007411 139 73 1,000 0,066817 0,10639424 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06718035 0,10690207 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06718035 0,10683142 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06718035 0,10676085 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06718035 0,10669038 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,06718035 0,10662001 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,06718035 0,10654972 ! protein complex disassembly GO:0043241 27 12 0,000 0,06718035 0,10647953 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06718035 0,10640943 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,06718035 0,10633943 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,06718035 0,10626951 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06718035 0,10619969 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06718035 0,10612996 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,06718035 0,10606032 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06718035 0,10599077 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06718035 0,10592132 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06718035 0,10585195 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06718035 0,10578268 ! drug transport GO:0015893 16 12 0,000 0,06718035 0,10571349 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06718035 0,1056444 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06718035 0,1055754 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06718035 0,10550648 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06718035 0,10543766 ! focal adhesion formation GO:0048041 35 12 0,000 0,06718035 0,10536892 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06718035 0,10530028 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06718035 0,10523173 ! forebrain cell migration GO:0021885 21 12 0,000 0,06718035 0,10516326 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06718035 0,10509488 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06718035 0,1050266 ! entry into host cell GO:0030260 32 12 0,000 0,06718035 0,1049584 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,06718035 0,10489029 ! monoamine transport GO:0015844 18 12 0,000 0,06718035 0,10482226 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06718035 0,10475433 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06718035 0,10468648 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06718035 0,10461873 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06718035 0,10455105 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06718035 0,10448347 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06718035 0,10441598 ! protein homotetramerization GO:0051289 21 12 0,000 0,06718035 0,10434857 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06718035 0,10428125 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06718035 0,10421401 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06718035 0,10414686 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06718035 0,1040798 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06718035 0,10401283 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06718035 0,10394594 ! cranial nerve development GO:0021545 20 12 0,000 0,06718035 0,10387913 ! fucose catabolic process GO:0019317 22 12 0,000 0,06718035 0,10381242 GO:0042355|L-fucose catabolic process, ! histone methylation GO:0016571 26 12 0,000 0,06718035 0,10374578 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06718035 0,10367924 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06718035 0,10361278 ! gland morphogenesis GO:0022612 29 12 0,000 0,06718035 0,1035464 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,06718035 0,10348011 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06718035 0,1034139 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06718035 0,10334778 ! spleen development GO:0048536 22 12 0,000 0,06718035 0,10328175 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,06718035 0,10321579 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06718035 0,10314992 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06718035 0,10308414 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06718035 0,10301844 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06718035 0,10295282 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,06718035 0,10288729 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06718035 0,10282184 ! response to cold GO:0009409 17 12 0,000 0,06718035 0,10275647 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06718035 0,10269119 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06718035 0,10262599 ! transition metal ion transport GO:0000041 126 74 1,000 0,06842022 0,10445371 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,06842022 0,10438747 ! organelle localization GO:0051640 136 74 1,000 0,06842022 0,10432132 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 1,000 0,0700361 0,10671744 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,0700361 0,1066499 ! cytosolic calcium ion homeostasis GO:0051480 135 76 1,000 0,07166443 0,10906048 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,07166443 0,10899154 ! defense response to bacterium GO:0042742 89 76 1,000 0,07166443 0,10892269 ! steroid biosynthetic process GO:0006694 131 76 1,000 0,07166443 0,10885393 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07257184 0,11016268 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07257184 0,11009322 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07257184 0,11002384 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07257184 0,10995456 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,07257184 0,10988536 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07257184 0,10981625 ! lipid localization GO:0010876 28 13 0,000 0,07257184 0,10974723 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,07257184 0,10967829 ! organelle fusion GO:0048284 32 13 0,000 0,07257184 0,10960944 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07257184 0,10954068 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07257184 0,109472 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07257184 0,10940341 ! endocrine pancreas development GO:0031018 22 13 0,000 0,07257184 0,1093349 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07257184 0,10926648 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07257184 0,10919815 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07257184 0,1091299 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07257184 0,10906174 ! methionine metabolic process GO:0006555 27 13 0,000 0,07257184 0,10899366 ! plasma membrane organization GO:0007009 24 13 0,000 0,07257184 0,10892566 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07257184 0,10885776 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07257184 0,10878993 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,07257184 0,10872219 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,07257184 0,10865454 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,07257184 0,10858697 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07257184 0,10851948 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,07257184 0,10845208 ! exocrine system development GO:0035272 32 13 0,000 0,07257184 0,10838476 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,07257184 0,10831752 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07257184 0,10825037 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07257184 0,1081833 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07257184 0,10811631 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07257184 0,10804941 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07257184 0,10798259 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07257184 0,10791585 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,07257184 0,10784919 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07257184 0,10778262 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07257184 0,10771613 ! ribosome assembly GO:0042255 17 13 0,000 0,07257184 0,10764972 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07257184 0,10758339 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07257184 0,10751714 ! chromatin silencing GO:0006342 26 13 0,000 0,07257184 0,10745098 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07257184 0,1073849 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07257184 0,10731889 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07257184 0,10725297 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07257184 0,10718713 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07257184 0,10712137 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,07257184 0,1070557 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07257184 0,1069901 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07257184 0,10692458 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07257184 0,10685914 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07257184 0,10679379 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07257184 0,10672851 ! embryonic placenta development GO:0001892 23 13 0,000 0,07257184 0,10666331 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,07257184 0,10659819 ! insulin secretion GO:0030073 23 13 0,000 0,07257184 0,10653315 ! actin filament polymerization GO:0030041 24 13 0,000 0,07257184 0,1064682 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,07257184 0,10640332 ! acrosome reaction GO:0007340 18 13 0,000 0,07257184 0,10633851 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,07330503 0,10734748 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,07662225 0,11213694 ! rRNA transcription GO:0009303 25 14 0,000 0,07793234 0,11398493 ! lactation GO:0007595 26 14 0,000 0,07793234 0,11391568 ! reproductive cellular process GO:0048610 20 14 0,000 0,07793234 0,11384651 ! tRNA modification GO:0006400 20 14 0,000 0,07793234 0,11377743 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,07793234 0,11370843 ! regulation of S phase GO:0033261 23 14 0,000 0,07793234 0,11363952 ! water transport GO:0006833 21 14 0,000 0,07793234 0,11357069 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07793234 0,11350194 ! non-recombinational repair GO:0000726 25 14 0,000 0,07793234 0,11343328 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,07793234 0,11336469 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07793234 0,1132962 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,07793234 0,11322778 ! RNA polyadenylation GO:0043631 30 14 0,000 0,07793234 0,11315945 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07793234 0,1130912 ! palate development GO:0060021 31 14 0,000 0,07793234 0,11302303 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07793234 0,11295494 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,07793234 0,11288694 ! arginine metabolic process GO:0006525 17 14 0,000 0,07793234 0,11281902 ! organic alcohol transport GO:0015850 29 14 0,000 0,07793234 0,11275118 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,07793234 0,11268342 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,07793234 0,11261574 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,07793234 0,11254814 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,07793234 0,11248063 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07793234 0,11241319 ! L-amino acid transport GO:0015807 30 14 0,000 0,07793234 0,11234584 ! stem cell development GO:0048864 43 14 0,000 0,07793234 0,11227857 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,07793234 0,11221137 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,07793234 0,11214426 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07793234 0,11207723 ! cerebellum development GO:0021549 21 14 0,000 0,07793234 0,11201028 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,07793234 0,11194341 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07793234 0,11187661 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,07793234 0,1118099 ! cofactor transport GO:0051181 26 14 0,000 0,07793234 0,11174327 ! NADP metabolic process GO:0006739 24 14 0,000 0,07793234 0,11167672 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,07793234 0,11161024 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07793234 0,11154385 ! intestinal absorption GO:0050892 25 14 0,000 0,07793234 0,11147753 ! oxygen transport GO:0015671 21 14 0,000 0,07793234 0,11141129 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07793234 0,11134513 ! male genitalia development GO:0030539 24 14 0,000 0,07793234 0,11127905 ! regulation of RNA stability GO:0043487 32 14 0,000 0,07793234 0,11121305 ! regulation of axon extension GO:0030516 37 14 0,000 0,07793234 0,11114713 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,07793234 0,11108128 ! response to metal ion GO:0010038 140 80 1,000 0,07829849 0,1115371 ! T cell activation GO:0042110 168 81 1,000 0,07998622 0,11387387 ! digestion GO:0007586 112 81 1,000 0,07998622 0,11380653 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,08168526 0,11615528 ! response to nutrient GO:0007584 125 82 1,000 0,08168526 0,11608667 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,08326203 0,11825764 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08326203 0,11818787 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,08326203 0,11811819 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,08326203 0,11804858 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,08326203 0,11797906 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,08326203 0,11790962 ! copper ion transport GO:0006825 20 15 0,000 0,08326203 0,11784026 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,08326203 0,11777099 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,08326203 0,11770179 ! sulfate transport GO:0008272 23 15 0,000 0,08326203 0,11763268 ! response to cAMP GO:0051591 22 15 0,000 0,08326203 0,11756364 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,08326203 0,11749469 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,08326203 0,11742582 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,08326203 0,11735703 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,08326203 0,11728832 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,08326203 0,11721969 ! response to hexose stimulus GO:0009746 22 15 0,000 0,08326203 0,11715114 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,08326203 0,11708267 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,08326203 0,11701428 ! pituitary gland development GO:0021983 29 15 0,000 0,08326203 0,11694597 ! vesicle coating GO:0006901 33 15 0,000 0,08326203 0,11687774 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,08326203 0,11680959 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,08326203 0,11674152 ! regulation of exocytosis GO:0017157 22 15 0,000 0,08326203 0,11667353 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,08326203 0,11660562 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,08326203 0,11653778 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,08326203 0,11647003 ! regulation of vasodilation GO:0042312 26 15 0,000 0,08326203 0,11640235 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,08326203 0,11633475 ! histone deacetylation GO:0016575 20 15 0,000 0,08326203 0,11626724 ! mRNA splice site selection GO:0006376 38 15 0,000 0,08326203 0,1161998 ! tissue regeneration GO:0042246 26 15 0,000 0,08326203 0,11613243 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08326203 0,11606515 ! muscle maintenance GO:0046716 26 15 0,000 0,08326203 0,11599794 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,08326203 0,11593081 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,08326203 0,11586376 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08326203 0,11579679 ! heme biosynthetic process GO:0006783 29 15 0,000 0,08326203 0,11572989 ! cell killing GO:0001906 29 15 0,000 0,08326203 0,11566308 ! detection of bacterium GO:0016045 18 15 0,000 0,08326203 0,11559633 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,08326203 0,11552967 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,08326203 0,11546308 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,08326203 0,11539657 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,08326203 0,11533014 ! peptide hormone processing GO:0016486 23 15 0,000 0,08326203 0,11526378 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,08511654 0,11776331 ! regulation of ligase activity GO:0051340 142 84 1,000 0,08511654 0,11769563 ! response to unfolded protein GO:0006986 131 85 1,000 0,08684842 0,12002142 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,08684842 0,11995252 GO:0002696|positive regulation of leukocyte activation, ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,08856109 0,12224785 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,08856109 0,12217775 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,08856109 0,12210773 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,08856109 0,1220378 ! bone remodeling GO:0046849 27 16 0,000 0,08856109 0,12196794 ! filopodium assembly GO:0046847 32 16 0,000 0,08856109 0,12189817 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,08856109 0,12182847 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,08856109 0,12175885 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,08856109 0,12168932 ! startle response GO:0001964 28 16 0,000 0,08856109 0,12161986 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,08856109 0,12155048 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,08856109 0,12148118 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,08856109 0,12141196 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,08856109 0,12134282 ! protein polyubiquitination GO:0000209 34 16 0,000 0,08856109 0,12127376 ! glutamate metabolic process GO:0006536 22 16 0,000 0,08856109 0,12120477 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,08856109 0,12113587 ! lysosomal transport GO:0007041 26 16 0,000 0,08856109 0,12106704 ! fructose metabolic process GO:0006000 25 16 0,000 0,08856109 0,12099829 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08856109 0,12092962 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08856109 0,12086103 ! intermediate filament-based process GO:0045103 32 16 0,000 0,08856109 0,12079251 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,08856109 0,12072408 ! negative regulation of immune response GO:0050777 35 16 0,000 0,08856109 0,12065572 ! axon cargo transport GO:0008088 43 16 0,000 0,08856109 0,12058743 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,08856109 0,12051923 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,08856109 0,1204511 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,08856109 0,12038305 ! neuron recognition GO:0008038 35 16 0,000 0,08856109 0,12031507 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,08856109 0,12024718 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,08856109 0,12017935 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,08856109 0,12011161 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,08856109 0,12004394 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,08856109 0,11997635 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,08856109 0,11990883 GO:0046466|membrane lipid catabolic process, ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,08856109 0,11984139 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08856109 0,11977403 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,08856109 0,11970674 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,08856109 0,11963953 ! defense response to virus GO:0051607 37 16 0,000 0,08856109 0,11957239 ! response to inorganic substance GO:0010035 153 86 1,000 0,08859087 0,1195455 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,09034373 0,12184249 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! positive regulation of cell killing GO:0031343 32 17 0,000 0,0938297 0,12647298 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,0938297 0,12640216 ! metencephalon development GO:0022037 30 17 0,000 0,0938297 0,12633143 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,0938297 0,12626077 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,0938297 0,1261902 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,0938297 0,1261197 ! signal complex assembly GO:0007172 41 17 0,000 0,0938297 0,12604928 ! endothelial cell migration GO:0043542 28 17 0,000 0,0938297 0,12597894 ! inositol metabolic process GO:0006020 28 17 0,000 0,0938297 0,12590868 ! gene silencing by RNA GO:0031047 36 17 0,000 0,0938297 0,1258385 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,0938297 0,12576839 ! glial cell development GO:0021782 27 17 0,000 0,0938297 0,12569837 ! adult walking behavior GO:0007628 33 17 0,000 0,0938297 0,12562842 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,0938297 0,12555855 ! heart looping GO:0001947 30 17 0,000 0,0938297 0,12548875 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,0938297 0,12541904 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,0938297 0,1253494 ! myoblast differentiation GO:0045445 45 17 0,000 0,0938297 0,12527984 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,0938297 0,12521035 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,0938297 0,12514095 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,0938297 0,12507162 ! glycine metabolic process GO:0006544 28 17 0,000 0,0938297 0,12500236 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,0938297 0,12493318 ! NAD metabolic process GO:0019674 29 17 0,000 0,0938297 0,12486408 ! membrane budding GO:0006900 37 17 0,000 0,0938297 0,12479506 ! DNA integration GO:0015074 29 17 0,000 0,0938297 0,12472611 ! regulation of protein binding GO:0043393 33 17 0,000 0,0938297 0,12465724 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,0938297 0,12458845 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,0938297 0,12451973 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,0938297 0,12445108 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,0938297 0,12438252 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,0938297 0,12431402 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,0938297 0,12424561 ! steroid catabolic process GO:0006706 31 17 0,000 0,0938297 0,12417726 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,0938297 0,124109 ! gas transport GO:0015669 25 17 0,000 0,0938297 0,12404081 ! organic cation transport GO:0015695 31 17 0,000 0,0938297 0,12397269 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,0938297 0,12390465 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,0938297 0,12383668 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,0938297 0,12376879 ! microspike assembly GO:0030035 36 17 0,000 0,0938297 0,12370097 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,0938297 0,12363322 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,09387994 0,12363171 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,09566295 0,12591086 ! response to protein stimulus GO:0051789 149 91 1,000 0,09745566 0,12820029 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,09906803 0,1302501 ! neuron maturation GO:0042551 42 18 0,000 0,09906803 0,13017896 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,09906803 0,1301079 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,09906803 0,13003692 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,09906803 0,12996602 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,09906803 0,12989519 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,09906803 0,12982444 ! memory GO:0007613 31 18 0,000 0,09906803 0,12975377 ! negative regulation of ion transport GO:0043271 24 18 0,000 0,09906803 0,12968318 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,09906803 0,12961266 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,09906803 0,12954222 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,09906803 0,12947185 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09906803 0,12940156 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,09906803 0,12933135 ! response to fungus GO:0009620 21 18 0,000 0,09906803 0,12926121 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,09906803 0,12919115 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,09906803 0,12912117 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,09906803 0,12905126 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,09906803 0,12898143 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,09906803 0,12891167 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,09906803 0,12884199 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,09906803 0,12877238 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,09906803 0,12870285 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,09906803 0,12863339 ! nerve development GO:0021675 28 18 0,000 0,09906803 0,12856401 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,09906803 0,12849471 ! phospholipid biosynthetic process GO:0008654 167 92 1,000 0,09925791 0,12867163 ! vitamin metabolic process GO:0006766 139 92 1,000 0,09925791 0,12860234 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,10106953 0,13087906 ! female pregnancy GO:0007565 164 94 1,000 0,10289035 0,13316524 ! protein secretion GO:0009306 39 19 0,000 0,10427625 0,13488637 ! positive regulation of translation GO:0045727 30 19 0,000 0,10427625 0,13481389 ! negative regulation of defense response GO:0031348 25 19 0,000 0,10427625 0,13474149 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,10427625 0,13466916 ! skin development GO:0043588 36 19 0,000 0,10427625 0,13459692 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,10427625 0,13452475 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,10427625 0,13445265 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,10427625 0,13438064 ! bile acid metabolic process GO:0008206 29 19 0,000 0,10427625 0,1343087 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,10427625 0,13423684 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,10427625 0,13416505 ! cerebral cortex development GO:0021987 36 19 0,000 0,10427625 0,13409335 ! pigmentation during development GO:0048066 41 19 0,000 0,10427625 0,13402172 ! heme metabolic process GO:0042168 36 19 0,000 0,10427625 0,13395016 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,10427625 0,13387868 ! plasma membrane fusion GO:0045026 28 19 0,000 0,10427625 0,13380728 ! protein export from nucleus GO:0006611 36 19 0,000 0,10427625 0,13373596 ! heart process GO:0003015 30 19 0,000 0,10427625 0,13366471 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,10427625 0,13359353 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,10427625 0,13352243 ! visual learning GO:0008542 36 19 0,000 0,10427625 0,13345141 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,10427625 0,13338046 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,10427625 0,13330959 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,10427625 0,1332388 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,10427625 0,13316807 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,10427625 0,13309743 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,10427625 0,13302686 ! cilium assembly GO:0042384 37 19 0,000 0,10427625 0,13295636 ! forebrain development GO:0030900 188 95 1,000 0,1047202 0,1334517 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,1047202 0,13338105 ! leukocyte differentiation GO:0002521 202 96 1,000 0,10655893 0,13565121 ! detection of stimulus GO:0051606 151 96 1,000 0,10655893 0,13557947 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,10945453 0,13919006 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,10945453 0,13911653 ! positive regulation of ossification GO:0045778 47 20 0,000 0,10945453 0,13904308 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,10945453 0,13896971 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,10945453 0,13889641 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,10945453 0,13882319 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,10945453 0,13875005 ! pancreas development GO:0031016 35 20 0,000 0,10945453 0,13867699 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,10945453 0,138604 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,10945453 0,13853109 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,10945453 0,13845825 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,10945453 0,1383855 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,10945453 0,13831281 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,10945453 0,13824021 ! stem cell differentiation GO:0048863 53 20 0,000 0,10945453 0,13816768 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,10945453 0,13809523 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,10945453 0,13802285 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,10945453 0,13795055 ! sensory perception of pain GO:0019233 30 20 0,000 0,10945453 0,13787832 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,10945453 0,13780617 ! diencephalon development GO:0021536 34 20 0,000 0,10945453 0,1377341 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,10945453 0,1376621 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,10945453 0,13759018 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,10945453 0,13751833 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,10945453 0,13744655 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,10945453 0,13737486 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,10945453 0,13730323 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,10945453 0,13723168 ! regulation of glucose import GO:0046324 29 20 0,000 0,10945453 0,13716021 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,10945453 0,13708881 ! actin filament-based movement GO:0030048 43 20 0,000 0,10945453 0,13701748 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,10945453 0,13694623 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,10945453 0,13687505 ! regulation of cell killing GO:0031341 42 21 0,000 0,11460305 0,14323892 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,11460305 0,14316455 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,11460305 0,14309026 ! glycerol metabolic process GO:0006071 34 21 0,000 0,11460305 0,14301604 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,11460305 0,1429419 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,11460305 0,14286784 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,11460305 0,14279385 ! axis specification GO:0009798 38 21 0,000 0,11460305 0,14271994 ! ovarian follicle development GO:0001541 35 21 0,000 0,11460305 0,14264611 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,11460305 0,14257235 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,11460305 0,14249867 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,11460305 0,14242507 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,11460305 0,14235154 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,11460305 0,14227809 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,11460305 0,14220471 ! vasodilation GO:0042311 39 21 0,000 0,11460305 0,14213141 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,11460305 0,14205818 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,11460305 0,14198503 ! DNA modification GO:0006304 34 21 0,000 0,11460305 0,14191196 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,11460305 0,14183896 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,11460305 0,14176603 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,11460305 0,14169318 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,11460305 0,14162041 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,11460305 0,14154771 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,11460305 0,14147508 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,11460305 0,14140253 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,11460305 0,14133005 ! collagen catabolic process GO:0030574 28 21 0,000 0,11460305 0,14125765 ! sperm-egg recognition GO:0035036 21 21 0,000 0,11460305 0,14118532 ! gut development GO:0048565 39 21 0,000 0,11460305 0,14111307 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,11972197 0,14734069 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,11972197 0,14726537 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,11972197 0,14719012 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,11972197 0,14711494 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,11972197 0,14703984 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,11972197 0,14696482 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,11972197 0,14688988 ! regeneration GO:0031099 41 22 0,000 0,11972197 0,14681501 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,11972197 0,14674022 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,11972197 0,14666551 ! sensory perception of taste GO:0050909 28 22 0,000 0,11972197 0,14659087 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,11972197 0,14651631 ! vacuolar transport GO:0007034 36 22 0,000 0,11972197 0,14644182 ! lysosome organization GO:0007040 41 22 0,000 0,11972197 0,14636741 ! central nervous system neuron development GO:0021954 46 22 0,000 0,11972197 0,14629307 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,11972197 0,14621881 ! fucose metabolic process GO:0006004 39 22 0,000 0,11972197 0,14614463 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,11972197 0,14607052 ! ureteric bud development GO:0001657 43 22 0,000 0,11972197 0,14599648 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,11972197 0,14592252 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,11972197 0,14584864 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,11972197 0,14577483 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,11972197 0,14570109 ! sarcomere organization GO:0045214 30 22 0,000 0,11972197 0,14562743 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,11972197 0,14555384 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,11972197 0,14548033 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,11972197 0,14540689 ! protein stabilization GO:0050821 39 22 0,000 0,11972197 0,14533353 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,12481146 0,15143539 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,12481146 0,15135906 ! viral genome replication GO:0019079 41 23 0,000 0,12481146 0,15128281 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,12481146 0,15120664 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,12481146 0,15113054 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,12481146 0,15105452 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,12481146 0,15097857 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,12481146 0,15090271 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,12481146 0,15082691 ! visual behavior GO:0007632 42 23 0,000 0,12481146 0,1507512 ! response to ethanol GO:0045471 46 23 0,000 0,12481146 0,15067556 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,12481146 0,15059999 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,12481146 0,1505245 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,12481146 0,15044909 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,12481146 0,15037375 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,12481146 0,15029849 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,12481146 0,1502233 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,12481146 0,15014819 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,12481146 0,15007316 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,12481146 0,14999819 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,12481146 0,14992331 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,12481146 0,14984849 ! fatty acid transport GO:0015908 44 23 0,000 0,12481146 0,14977376 ! platelet activation GO:0030168 37 23 0,000 0,12481146 0,14969909 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,12481146 0,14962451 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,12481146 0,14954999 ! cell-cell recognition GO:0009988 25 23 0,000 0,12481146 0,14947555 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,12481146 0,14940119 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,12481146 0,14932689 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,12481146 0,14925268 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,12481146 0,14917853 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,1298717 0,15514961 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,1298717 0,15507261 ! vesicle docking GO:0048278 47 24 0,000 0,1298717 0,15499569 ! spinal cord development GO:0021510 47 24 0,000 0,1298717 0,15491885 ! vacuole organization GO:0007033 43 24 0,000 0,1298717 0,15484208 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,1298717 0,15476539 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,1298717 0,15468877 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,1298717 0,15461223 ! regulation of behavior GO:0050795 43 24 0,000 0,1298717 0,15453576 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,1298717 0,15445938 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,1298717 0,15438306 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,1298717 0,15430682 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,1298717 0,15423066 ! pentose metabolic process GO:0019321 35 24 0,000 0,1298717 0,15415457 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,1298717 0,15407856 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,1298717 0,15400262 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,1298717 0,15392676 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,1298717 0,15385097 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,1298717 0,15377525 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,1298717 0,15369961 ! regulation of amine transport GO:0051952 40 24 0,000 0,1298717 0,15362405 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,13490285 0,15949693 ! phototransduction GO:0007602 33 25 0,000 0,13490285 0,15941859 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,13490285 0,15934033 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,13490285 0,15926215 ! sperm motility GO:0030317 31 25 0,000 0,13490285 0,15918404 ! receptor metabolic process GO:0043112 46 25 0,000 0,13490285 0,15910601 ! chromosome condensation GO:0030261 45 25 0,000 0,13490285 0,15902805 ! osteoblast differentiation GO:0001649 60 25 0,000 0,13490285 0,15895017 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,13490285 0,15887237 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,13490285 0,15879465 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,13490285 0,158717 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,13490285 0,15863942 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,13490285 0,15856192 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,13490285 0,1584845 ! telomere organization GO:0032200 43 25 0,000 0,13490285 0,15840715 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,13490285 0,15832988 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,13490285 0,15825269 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,13990507 0,16404074 ! embryonic pattern specification GO:0009880 44 26 0,000 0,13990507 0,16396084 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,13990507 0,16388102 ! initiation of viral infection GO:0019059 57 26 0,000 0,13990507 0,16380127 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,13990507 0,1637216 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,13990507 0,16364201 ! tube lumen formation GO:0035148 50 26 0,000 0,13990507 0,16356249 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,13990507 0,16348305 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,13990507 0,16340369 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,13990507 0,16332441 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,13990507 0,1632452 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,13990507 0,16316607 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,13990507 0,16308702 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,13990507 0,16300804 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,13990507 0,16292914 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,13990507 0,16285032 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,13990507 0,16277157 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,13990507 0,1626929 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,13990507 0,1626143 ! blastocyst development GO:0001824 49 26 0,000 0,13990507 0,16253578 ! leukocyte proliferation GO:0070661 52 26 0,000 0,13990507 0,16245734 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,13990507 0,16237897 ! neuron fate commitment GO:0048663 48 27 0,000 0,14487854 0,16807028 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,14487854 0,16798928 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,14487854 0,16790836 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,14487854 0,16782752 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,14487854 0,16774676 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,14487854 0,16766607 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,14487854 0,16758546 ! autophagy GO:0006914 41 27 0,000 0,14487854 0,16750493 ! male gonad development GO:0008584 44 27 0,000 0,14487854 0,16742448 ! response to toxin GO:0009636 47 27 0,000 0,14487854 0,1673441 ! primary neural tube formation GO:0014020 51 27 0,000 0,14487854 0,1672638 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,14487854 0,16718358 ! glutathione metabolic process GO:0006749 39 27 0,000 0,14487854 0,16710343 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,14487854 0,16702336 ! circadian rhythm GO:0007623 50 28 0,000 0,14982341 0,17264134 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,14982341 0,1725587 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,14982341 0,17247613 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,14982341 0,17239365 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,14982341 0,17231124 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,14982341 0,17222891 ! synaptogenesis GO:0007416 42 28 0,000 0,14982341 0,17214667 ! lipid oxidation GO:0034440 43 28 0,000 0,14982341 0,1720645 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,14982341 0,1719824 ! translational initiation GO:0006413 65 29 0,000 0,15473985 0,17754128 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,15473985 0,17745666 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,15473985 0,17737212 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,15473985 0,17728765 ! catechol metabolic process GO:0009712 54 29 0,000 0,15473985 0,17720327 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,15473985 0,17711897 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,15473985 0,17703475 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 55 29 0,000 0,15473985 0,1769506 ! cell fate determination GO:0001709 60 29 0,000 0,15473985 0,17686654 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,15473985 0,17678256 ! detection of light stimulus GO:0009583 38 29 0,000 0,15473985 0,17669866 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,15473985 0,17661483 ! phenol metabolic process GO:0018958 55 30 0,000 0,15962802 0,18210764 ! zinc ion transport GO:0006829 45 30 0,000 0,15962802 0,18202133 ! membrane docking GO:0022406 61 30 0,000 0,15962802 0,18193511 ! cell junction assembly GO:0034329 78 30 0,000 0,15962802 0,18184896 ! regulation of innate immune response GO:0045088 51 30 0,000 0,15962802 0,1817629 ! acute-phase response GO:0006953 49 30 0,000 0,15962802 0,18167692 ! myofibril assembly GO:0030239 47 30 0,000 0,15962802 0,18159102 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,15962802 0,1815052 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,15962802 0,18141947 ! phospholipid transport GO:0015914 51 30 0,000 0,15962802 0,18133381 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,15962802 0,18124823 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,15962802 0,18116274 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,15962802 0,18107733 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,16448808 0,18650251 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,16448808 0,18641466 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,16448808 0,18632689 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,16448808 0,18623921 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,16448808 0,18615161 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,16448808 0,18606409 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,16448808 0,18597665 ! ovulation cycle process GO:0022602 49 31 0,000 0,16448808 0,1858893 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,16448808 0,18580203 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,16448808 0,18571484 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,16448808 0,18562773 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,16448808 0,1855407 ! mesoderm formation GO:0001707 69 31 0,000 0,16448808 0,18545376 ! natural killer cell activation GO:0030101 45 31 0,000 0,16448808 0,18536689 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,16448808 0,18528011 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,16448808 0,18519341 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,16448808 0,18510679 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,16448808 0,18502025 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,1693202 0,19036654 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,1693202 0,19027762 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,1693202 0,19018879 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,1693202 0,19010004 ! cholesterol transport GO:0030301 56 32 0,000 0,1693202 0,19001138 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,1693202 0,18992279 ! spindle organization GO:0007051 46 32 0,000 0,1693202 0,18983429 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,1693202 0,18974588 ! metanephros development GO:0001656 74 32 0,000 0,1693202 0,18965754 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,1693202 0,18956929 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,1693202 0,18948111 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,1693202 0,18939302 ! muscle cell development GO:0055001 49 32 0,000 0,1693202 0,18930502 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,1693202 0,18921709 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,1693202 0,18912925 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,1693202 0,18904148 ! ovulation cycle GO:0042698 51 32 0,000 0,1693202 0,1889538 ! BMP signaling pathway GO:0030509 64 32 0,000 0,1693202 0,1888662 ! hindbrain development GO:0030902 61 32 0,000 0,1693202 0,18877868 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,1693202 0,18869124 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,1693202 0,18860389 ! gene silencing GO:0016458 65 32 0,000 0,1693202 0,18851661 ! post-embryonic development GO:0009791 69 33 0,000 0,17412453 0,19377595 ! protein targeting to membrane GO:0006612 68 33 0,000 0,17412453 0,19368637 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,17412453 0,19359686 ! ceramide metabolic process GO:0006672 64 33 0,000 0,17412453 0,19350744 ! formation of primary germ layer GO:0001704 72 33 0,000 0,17412453 0,1934181 ! cell fate specification GO:0001708 52 33 0,000 0,17412453 0,19332885 ! sterol transport GO:0015918 57 33 0,000 0,17412453 0,19323967 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,17412453 0,19315058 ! adult locomotory behavior GO:0008344 59 33 0,000 0,17412453 0,19306157 ! glial cell differentiation GO:0010001 63 34 0,000 0,17890123 0,1982664 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,17890123 0,19817512 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,17890123 0,19808392 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,17890123 0,19799281 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,17890123 0,19790178 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,17890123 0,19781083 ! spermatid development GO:0007286 63 34 0,000 0,17890123 0,19771996 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,17890123 0,19762918 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,17890123 0,19753849 ! odontogenesis GO:0042476 66 35 0,000 0,18365046 0,20268946 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,18365046 0,20259652 ! female gonad development GO:0008585 58 35 0,000 0,18365046 0,20250367 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,18365046 0,20241091 GO:0006639|acylglycerol metabolic process, ! cytokine production GO:0001816 59 35 0,000 0,18365046 0,20231823 ! neural tube formation GO:0001841 67 35 0,000 0,18365046 0,20222564 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,18837238 0,20733026 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,18837238 0,20723546 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,18837238 0,20714075 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,18837238 0,20704612 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,18837238 0,20695158 ! positive regulation of cell development GO:0010720 80 36 0,000 0,18837238 0,20685712 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,18837238 0,20676275 ! aerobic respiration GO:0009060 55 36 0,000 0,18837238 0,20666847 ! RNA export from nucleus GO:0006405 56 37 0,000 0,19306715 0,21172268 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,19306715 0,21162622 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,19306715 0,21152985 ! sister chromatid segregation GO:0000819 58 37 0,000 0,19306715 0,21143357 ! actomyosin structure organization GO:0031032 62 37 0,000 0,19306715 0,21133738 ! organic anion transport GO:0015711 68 37 0,000 0,19306715 0,21124127 ! tissue remodeling GO:0048771 76 37 0,000 0,19306715 0,21114525 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,19306715 0,21104932 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,19306715 0,21095348 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,19306715 0,21085772 ! spermatid differentiation GO:0048515 66 37 0,000 0,19306715 0,21076205 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,19773491 0,21575973 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,19773491 0,21566192 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,19773491 0,2155642 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,19773491 0,21546658 ! lipid homeostasis GO:0055088 67 38 0,000 0,19773491 0,21536904 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,19773491 0,21527158 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,19773491 0,21517422 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,19773491 0,21507694 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,19773491 0,21497976 ! mRNA catabolic process GO:0006402 71 39 0,000 0,20237583 0,21992604 ! organic ether metabolic process GO:0018904 55 39 0,000 0,20237583 0,21982675 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,20237583 0,21972755 ! ion transmembrane transport GO:0034220 66 39 0,000 0,20237583 0,21962844 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,20237583 0,21952942 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,20237583 0,21943048 ! RNA modification GO:0009451 57 39 0,000 0,20237583 0,21933164 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,20237583 0,21923289 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,20699005 0,22413054 ! feeding behavior GO:0007631 59 40 0,000 0,20699005 0,22402972 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,20699005 0,22392899 ! maintenance of protein location GO:0045185 91 40 0,000 0,20699005 0,22382834 ! cytokinesis GO:0000910 72 40 0,000 0,20699005 0,22372779 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,21157773 0,22858376 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,21157773 0,22848116 ! gliogenesis GO:0042063 88 41 0,000 0,21157773 0,22837866 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,21157773 0,22827625 ! polyol metabolic process GO:0019751 66 41 0,000 0,21157773 0,22817393 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,21613903 0,23298858 ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,21613903 0,23288424 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,21613903 0,23277999 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,21613903 0,23267584 ! neuron migration GO:0001764 79 42 0,000 0,21613903 0,23257178 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,21613903 0,23246781 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,22067408 0,23723943 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,22067408 0,23713347 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,22067408 0,23702761 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,22067408 0,23692184 ! neural tube development GO:0021915 77 43 0,000 0,22067408 0,23681617 ! striated muscle contraction GO:0006941 77 43 0,000 0,22067408 0,23671059 ! phagocytosis GO:0006909 90 43 0,000 0,22067408 0,2366051 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,22067408 0,23649971 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,22518305 0,24122459 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,22518305 0,24111723 ! male sex differentiation GO:0046661 76 44 0,000 0,22518305 0,24100998 ! biopolymer methylation GO:0043414 84 44 0,000 0,22518305 0,24090281 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,22518305 0,24079574 ! maintenance of location in cell GO:0051651 97 44 0,000 0,22518305 0,24068877 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,22966608 0,24537149 ! glycolysis GO:0006096 65 45 0,000 0,22966608 0,24526258 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,22966608 0,24515377 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,22966608 0,24504505 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,22966608 0,24493643 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,22966608 0,24482791 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,23412332 0,24946887 ! positive regulation of defense response GO:0031349 76 47 0,000 0,23855492 0,25407841 ! endosome transport GO:0016197 108 47 0,000 0,23855492 0,25396599 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,23855492 0,25385366 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,23855492 0,25374144 ! JNK cascade GO:0007254 91 47 0,000 0,23855492 0,25362931 ! methylation GO:0032259 90 47 0,000 0,23855492 0,25351728 ! protein homooligomerization GO:0051260 76 47 0,000 0,23855492 0,25340536 ! Notch signaling pathway GO:0007219 96 48 0,000 0,24296102 0,25797185 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,24296102 0,25785806 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,24296102 0,25774436 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,24296102 0,25763077 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,24296102 0,25751727 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,24734177 0,26204504 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,24734177 0,26192971 ! regulation of ion transport GO:0043269 77 49 0,000 0,24734177 0,26181447 ! peptide metabolic process GO:0006518 76 49 0,000 0,24734177 0,26169934 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,24734177 0,26158431 ! endocrine system development GO:0035270 104 49 0,000 0,24734177 0,26146937 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,25169731 0,26595685 ! neuromuscular process GO:0050905 99 50 0,000 0,25169731 0,2658401 ! regulation of ossification GO:0030278 117 50 0,000 0,25169731 0,26572345 ! inner ear development GO:0048839 79 50 0,000 0,25169731 0,2656069 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,25169731 0,26549046 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,25169731 0,26537412 ! viral infectious cycle GO:0019058 99 51 0,000 0,2560278 0,26982167 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,2560278 0,26970354 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,2560278 0,26958551 ! chromatin remodeling GO:0006338 109 51 0,000 0,2560278 0,26946758 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,2560278 0,26934975 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,2560278 0,26923203 ! membrane fusion GO:0006944 110 52 0,000 0,26033336 0,27364005 ! amino acid activation GO:0043038 92 52 0,000 0,26033336 0,27352056 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,26461416 0,27789684 ! RNA catabolic process GO:0006401 93 53 0,000 0,26461416 0,27777559 ! regulation of translational initiation GO:0006446 82 53 0,000 0,26461416 0,27765445 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,26461416 0,27753342 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,26461416 0,27741249 ! cell recognition GO:0008037 85 54 0,000 0,26887031 0,28175173 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,26887031 0,28162907 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,26887031 0,28150652 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,26887031 0,28138407 ! chloride transport GO:0006821 90 55 0,000 0,27310198 0,28568842 ! glucose catabolic process GO:0006007 82 55 0,000 0,27310198 0,28556426 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,27310198 0,28544021 ! gastrulation GO:0007369 112 55 0,000 0,27310198 0,28531627 ! nuclear export GO:0051168 97 55 0,000 0,27310198 0,28519243 ! sensory perception of smell GO:0007608 80 56 0,000 0,27730929 0,28946037 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,27730929 0,28933485 ! proton transport GO:0015992 94 56 0,000 0,27730929 0,28920943 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,28149239 0,29344484 ! maintenance of location GO:0051235 118 57 0,000 0,28149239 0,29331776 ! hydrogen transport GO:0006818 97 58 0,000 0,28565142 0,29752265 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,28565142 0,29739391 ! regulation of endocytosis GO:0030100 91 58 0,000 0,28565142 0,29726528 ! adult behavior GO:0030534 99 58 0,000 0,28565142 0,29713676 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,28978651 0,30130784 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,28978651 0,30117769 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,2938978 0,3053187 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,2938978 0,30518692 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,2938978 0,30505527 ! kidney development GO:0001822 122 60 0,000 0,2938978 0,30492372 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,29798543 0,30903144 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,29798543 0,30889829 ! mesoderm development GO:0007498 119 61 0,000 0,29798543 0,30876526 ! tRNA processing GO:0008033 89 61 0,000 0,29798543 0,30863234 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,29798543 0,30849954 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,30204952 0,31257254 ! gonad development GO:0008406 98 62 0,000 0,30204952 0,31243816 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,30609023 0,31648177 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,30609023 0,31634583 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,31010767 0,32036027 ! cell redox homeostasis GO:0045454 102 64 0,000 0,31010767 0,32022277 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,31010767 0,3200854 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,31010767 0,31994814 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,31410199 0,3239303 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,31410199 0,32379151 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,31410199 0,32365285 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 0,000 0,31410199 0,3235143 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,31807332 0,32746444 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,31807332 0,32732438 ! extracellular matrix organization GO:0030198 133 66 0,000 0,31807332 0,32718444 ! chromosome segregation GO:0007059 113 67 0,000 0,32202178 0,33110445 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,32202178 0,33096301 ! hexose catabolic process GO:0019320 104 67 0,000 0,32202178 0,33082169 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,32202178 0,3306805 ! activation of immune response GO:0002253 105 67 0,000 0,32202178 0,33053942 ! amino acid transport GO:0006865 125 68 0,000 0,32594751 0,33442632 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,32594751 0,33428376 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,32594751 0,33414133 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,32594751 0,33399902 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,32985064 0,33785468 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,32985064 0,33771091 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,32985064 0,33756726 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,32985064 0,33742374 ! antigen processing and presentation GO:0019882 104 69 0,000 0,32985064 0,33728034 ! appendage morphogenesis GO:0035107 135 70 0,000 0,3337313 0,34110344 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,33758961 0,34490047 ! appendage development GO:0048736 136 71 0,000 0,33758961 0,34475408 GO:0060173|limb development, ! acute inflammatory response GO:0002526 113 72 0,000 0,34142571 0,34852366 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,34142571 0,34837585 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,34142571 0,34822817 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,34523972 0,35196897 ! fertilization GO:0009566 90 73 0,000 0,34523972 0,35181989 ! neurotransmitter transport GO:0006836 123 74 0,000 0,34903177 0,35553363 ! exocytosis GO:0006887 133 74 0,000 0,34903177 0,35538317 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,35280198 0,35907003 ! rhythmic process GO:0048511 128 75 0,000 0,35280198 0,35891821 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,35655048 0,36257838 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,36027739 0,36621352 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,36027739 0,36605887 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,36398284 0,36966767 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,36766695 0,37325177 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,36766695 0,37309434 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,37132985 0,37665245 ! muscle cell differentiation GO:0042692 159 80 0,000 0,37132985 0,37649372 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,37132985 0,37633513 ! inorganic anion transport GO:0015698 138 80 0,000 0,37132985 0,37617668 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,37497164 0,37970613 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,37859246 0,38321138 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,37859246 0,38305024 ! regulation of lyase activity GO:0051339 160 83 0,000 0,38219242 0,38653004 ! nucleosome assembly GO:0006334 122 85 0,000 0,38933026 0,39358345 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,38933026 0,39341815 ! amine biosynthetic process GO:0009309 138 86 0,000 0,39286837 0,39682674 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,39286837 0,39666022 ! chromatin assembly GO:0031497 124 86 0,000 0,39286837 0,39649384 ! alcohol catabolic process GO:0046164 130 86 0,000 0,39286837 0,39632759 ! amine transport GO:0015837 155 86 0,000 0,39286837 0,39616149 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,3963861 0,39954125 ! cellular respiration GO:0045333 135 88 0,000 0,39988356 0,40289776 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,39988356 0,40272911 ! cellular defense response GO:0006968 114 89 0,000 0,40336088 0,4060612 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,40681816 0,40937034 ! sterol metabolic process GO:0016125 152 91 0,000 0,41025552 0,41265668 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,41025552 0,41248424 ! regulation of defense response GO:0031347 149 92 0,000 0,41367308 0,41574662 ! nucleosome organization GO:0034728 138 92 0,000 0,41367308 0,41557304 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,41707094 0,41881164 GO:0010498|proteasomal protein catabolic process, ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,42044923 0,42202788 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,42714751 0,42857252 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,42714751 0,42839388 ! positive regulation of immune response GO:0050778 156 96 0,000 0,42714751 0,42821538 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,43046773 0,43136416 ! response to virus GO:0009615 160 98 0,000 0,43376882 0,43449116 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,43376882 0,43431035 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,43376882 0,43412969 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,43705088 0,4372326 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,43705088 0,43705088