pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6534-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! G1/S transition of mitotic cell cycle GO:0000082 124 46 7,000 1,209E-10 2,953E-07 ! response to UV GO:0009411 120 55 7,000 5,415E-10 6,615E-07 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 7,000 7,283E-10 5,931E-07 ! apoptotic mitochondrial changes GO:0008637 42 20 5,000 7,604E-10 4,644E-07 ! interphase of mitotic cell cycle GO:0051329 224 98 8,000 2,939E-09 1,436E-06 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 4,000 3,265E-08 1,33E-05 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 3,000 5,331E-08 1,861E-05 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 3,000 5,331E-08 1,628E-05 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 4,000 7,655E-08 2,078E-05 ! cell structure disassembly during apoptosis GO:0006921 32 21 4,000 7,655E-08 1,87E-05 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 3,000 9,556E-08 2,122E-05 ! induction of apoptosis by intracellular signals GO:0008629 95 45 5,000 1,431E-07 2,913E-05 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 3,000 1,586E-07 2,981E-05 ! positive regulation of cell cycle GO:0045787 96 48 5,000 2,128E-07 3,713E-05 ! insulin receptor signaling pathway GO:0008286 66 27 4,000 2,959E-07 4,82E-05 ! regulation of B cell proliferation GO:0030888 22 12 3,000 3,708E-07 5,661E-05 ! negative regulation of mast cell proliferation GO:0070667 24 12 3,000 3,708E-07 5,328E-05 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of MAP kinase activity GO:0043406 174 93 6,000 6,925E-07 9,399E-05 ! release of cytochrome c from mitochondria GO:0001836 31 14 3,000 7,435E-07 9,56E-05 ! negative regulation of leukocyte proliferation GO:0070664 32 16 3,000 1,341E-06 1,638E-04 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! DNA fragmentation involved in apoptosis GO:0006309 27 17 3,000 1,746E-06 2,031E-04 ! negative regulation of blood coagulation GO:0030195 25 17 3,000 1,746E-06 1,939E-04 ! cellular response to insulin stimulus GO:0032869 85 38 4,000 1,755E-06 1,864E-04 ! negative regulation of B cell activation GO:0050869 14 6 2,000 2,925E-06 2,977E-04 ! negative regulation of T cell activation GO:0050868 41 20 3,000 3,51E-06 3,43E-04 ! negative regulation of coagulation GO:0050819 30 20 3,000 3,51E-06 3,298E-04 ! energy reserve metabolic process GO:0006112 76 44 4,000 3,7E-06 3,348E-04 ! regulation of helicase activity GO:0051095 16 7 2,000 5,098E-06 4,448E-04 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 5,098E-06 4,295E-04 ! fibrinolysis GO:0042730 11 7 2,000 5,098E-06 4,152E-04 ! response to insulin stimulus GO:0032868 98 47 4,000 5,159E-06 4,065E-04 ! apoptotic nuclear changes GO:0030262 34 22 3,000 5,256E-06 4,012E-04 ! cellular component disassembly GO:0022411 89 48 4,000 5,734E-06 4,245E-04 ! regulation of mast cell proliferation GO:0070666 89 49 4,000 6,358E-06 4,568E-04 ! cellular response to hormone stimulus GO:0032870 182 85 5,000 6,442E-06 4,497E-04 ! mitochondrion organization GO:0007005 159 87 5,000 7,373E-06 5,003E-04 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 3,000 7,571E-06 4,999E-04 ! negative regulation of phosphorylation GO:0042326 52 24 3,000 7,571E-06 4,867E-04 ! ER overload response GO:0006983 13 8 2,000 8,126E-06 5,09E-04 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 8,126E-06 4,963E-04 ! regulation of leukocyte proliferation GO:0070663 97 53 4,000 9,405E-06 5,604E-04 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! negative regulation of phosphorus metabolic process GO:0010563 56 26 3,000 1,056E-05 6,145E-04 GO:0045936|negative regulation of phosphate metabolic process, ! response to endoplasmic reticulum stress GO:0034976 46 26 3,000 1,056E-05 6,002E-04 ! regulation of blood coagulation GO:0030193 46 26 3,000 1,056E-05 5,865E-04 ! middle ear morphogenesis GO:0042474 14 9 2,000 1,214E-05 6,591E-04 ! negative regulation of multicellular organismal process GO:0051241 174 95 5,000 1,225E-05 6,506E-04 ! negative regulation of lymphocyte activation GO:0051250 55 27 3,000 1,235E-05 6,419E-04 ! regulation of DNA metabolic process GO:0051052 188 97 5,000 1,381E-05 7,027E-04 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 3,000 1,435E-05 7,153E-04 ! ER-nuclear signaling pathway GO:0006984 52 29 3,000 1,657E-05 8,098E-04 ! regulation of B cell activation GO:0050864 55 30 3,000 1,905E-05 9,123E-04 ! regulation of coagulation GO:0050818 52 30 3,000 1,905E-05 8,948E-04 ! negative regulation of leukocyte activation GO:0002695 60 31 3,000 2,178E-05 1,004E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 2,000 2,366E-05 1,07E-03 ! protein amino acid autophosphorylation GO:0046777 157 64 4,000 2,383E-05 1,059E-03 ! response to peptide hormone stimulus GO:0043434 129 64 4,000 2,383E-05 1,04E-03 ! positive regulation of catabolic process GO:0009896 72 32 3,000 2,478E-05 1,062E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 2,000 3,142E-05 1,324E-03 ! T cell homeostasis GO:0043029 28 12 2,000 3,142E-05 1,301E-03 ! negative regulation of cell size GO:0045792 144 69 4,000 3,438E-05 1,4E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 4,000 3,438E-05 1,377E-03 ! negative regulation of kinase activity GO:0033673 145 70 4,000 3,687E-05 1,453E-03 ! regulation of monooxygenase activity GO:0032768 35 13 2,000 4,069E-05 1,578E-03 ! negative regulation of cell activation GO:0050866 69 37 3,000 4,458E-05 1,702E-03 ! negative regulation of transferase activity GO:0051348 155 74 4,000 4,824E-05 1,813E-03 ! regulation of catabolic process GO:0009894 173 77 4,000 5,841E-05 2,162E-03 ! nucleus organization GO:0006997 73 40 3,000 6,093E-05 2,222E-03 ! lymphocyte homeostasis GO:0002260 33 15 2,000 6,423E-05 2,308E-03 ! positive regulation of phosphorylation GO:0042327 149 81 4,000 7,445E-05 2,636E-03 ! glucose transport GO:0015758 66 43 3,000 8,126E-05 2,836E-03 ! regulation of T cell proliferation GO:0042129 80 43 3,000 8,126E-05 2,796E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 4,000 8,365E-05 2,838E-03 GO:0045937|positive regulation of phosphate metabolic process, ! hexose transport GO:0008645 68 44 3,000 8,901E-05 2,979E-03 GO:0015749|monosaccharide transport, ! regulation of survival gene product expression GO:0045884 38 17 2,000 9,524E-05 3,144E-03 ! branching morphogenesis of a tube GO:0048754 102 45 3,000 9,729E-05 3,169E-03 ! regulation of protein transport GO:0051223 165 87 4,000 1,046E-04 3,364E-03 GO:0070201|regulation of establishment of protein localization, ! patterning of blood vessels GO:0001569 43 18 2,000 1,138E-04 3,612E-03 ! positive regulation of hormone secretion GO:0046887 35 19 2,000 1,347E-04 4,218E-03 ! activation of caspase activity GO:0006919 95 50 3,000 1,473E-04 4,555E-03 ! peptidyl-serine phosphorylation GO:0018105 44 20 2,000 1,578E-04 4,819E-03 ! negative regulation of immune system process GO:0002683 101 51 3,000 1,592E-04 4,801E-03 ! morphogenesis of a branching structure GO:0001763 116 52 3,000 1,717E-04 5,116E-03 ! regulation of protein localization GO:0032880 188 97 4,000 1,749E-04 5,147E-03 ! regulation of vasoconstriction GO:0019229 40 21 2,000 1,834E-04 5,334E-03 ! camera-type eye morphogenesis GO:0048593 47 21 2,000 1,834E-04 5,271E-03 ! positive regulation of growth GO:0045927 96 53 3,000 1,85E-04 5,255E-03 ! positive regulation of protein catabolic process GO:0045732 44 22 2,000 2,115E-04 5,939E-03 ! peptidyl-serine modification GO:0018209 50 22 2,000 2,115E-04 5,872E-03 ! regulation of protein catabolic process GO:0042176 126 56 3,000 2,292E-04 6,29E-03 ! regulation of DNA replication GO:0006275 105 56 3,000 2,292E-04 6,22E-03 ! activation of pro-apoptotic gene products GO:0008633 51 23 2,000 2,423E-04 6,505E-03 ! gluconeogenesis GO:0006094 38 23 2,000 2,423E-04 6,434E-03 ! positive regulation of caspase activity GO:0043280 108 57 3,000 2,454E-04 6,447E-03 GO:0010952|positive regulation of peptidase activity, ! positive regulation of cell migration GO:0030335 137 58 3,000 2,625E-04 6,823E-03 ! aging GO:0007568 112 58 3,000 2,625E-04 6,751E-03 ! regulation of cellular catabolic process GO:0031329 55 24 2,000 2,758E-04 7,019E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 2,758E-04 6,947E-03 ! regulation of oxidoreductase activity GO:0051341 48 24 2,000 2,758E-04 6,876E-03 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 1,000 2,783E-04 6,868E-03 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of helicase activity GO:0051096 12 5 1,000 2,783E-04 6,799E-03 ! female meiosis GO:0007143 10 5 1,000 2,783E-04 6,732E-03 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 1,000 2,783E-04 6,666E-03 ! 2-oxoglutarate metabolic process GO:0006103 10 5 1,000 2,783E-04 6,601E-03 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 2,783E-04 6,538E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 2,783E-04 6,475E-03 ! anagen GO:0042640 7 5 1,000 2,783E-04 6,414E-03 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 1,000 2,783E-04 6,354E-03 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 2,783E-04 6,295E-03 ! microvillus organization GO:0032528 8 5 1,000 2,783E-04 6,238E-03 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 1,000 2,783E-04 6,181E-03 ! muscle cell migration GO:0014812 8 5 1,000 2,783E-04 6,125E-03 ! response to food GO:0032094 6 5 1,000 2,783E-04 6,071E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 2,783E-04 6,017E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 1,000 2,783E-04 5,964E-03 ! B cell homeostasis GO:0001782 13 5 1,000 2,783E-04 5,912E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 2,783E-04 5,861E-03 ! stem cell division GO:0017145 11 5 1,000 2,783E-04 5,811E-03 GO:0048103|somatic stem cell division, ! DNA catabolic process GO:0006308 94 60 3,000 2,992E-04 6,195E-03 ! protein import into nucleus, translocation GO:0000060 51 25 2,000 3,122E-04 6,409E-03 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 2,000 3,122E-04 6,356E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 2,000 3,122E-04 6,304E-03 ! leukocyte homeostasis GO:0001776 50 25 2,000 3,122E-04 6,252E-03 ! protein tetramerization GO:0051262 57 25 2,000 3,122E-04 6,201E-03 ! pyruvate metabolic process GO:0006090 43 26 2,000 3,516E-04 6,926E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 2,000 3,516E-04 6,871E-03 ! negative regulation of cell development GO:0010721 83 26 2,000 3,516E-04 6,816E-03 GO:0050768|negative regulation of neurogenesis, ! positive regulation of nuclear division GO:0051785 41 26 2,000 3,516E-04 6,763E-03 GO:0045840|positive regulation of mitosis, ! positive regulation of cell motion GO:0051272 157 65 3,000 4,07E-04 7,767E-03 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 1,000 4,16E-04 7,878E-03 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 1,000 4,16E-04 7,818E-03 ! vascular smooth muscle contraction GO:0014829 13 6 1,000 4,16E-04 7,758E-03 ! positive regulation of muscle hypertrophy GO:0014742 10 6 1,000 4,16E-04 7,699E-03 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! neuron apoptosis GO:0051402 15 6 1,000 4,16E-04 7,641E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 4,16E-04 7,584E-03 ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 4,16E-04 7,528E-03 ! negative regulation of gliogenesis GO:0014014 18 6 1,000 4,16E-04 7,473E-03 GO:0045686|negative regulation of glial cell differentiation, ! hair follicle maturation GO:0048820 8 6 1,000 4,16E-04 7,418E-03 ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 4,16E-04 7,364E-03 ! progesterone metabolic process GO:0042448 12 6 1,000 4,16E-04 7,311E-03 ! determination of adult lifespan GO:0008340 17 6 1,000 4,16E-04 7,259E-03 ! ear development GO:0043583 114 66 3,000 4,314E-04 7,475E-03 ! regulation of fibroblast proliferation GO:0048145 56 28 2,000 4,395E-04 7,561E-03 ! peptidyl-tyrosine modification GO:0018212 57 28 2,000 4,395E-04 7,509E-03 ! negative regulation of cell growth GO:0030308 142 67 3,000 4,569E-04 7,752E-03 ! activation of MAPK activity GO:0000187 124 67 3,000 4,569E-04 7,699E-03 ! cellular iron ion homeostasis GO:0006879 57 29 2,000 4,883E-04 8,171E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 3,000 5,111E-04 8,494E-03 ! positive regulation of multicellular organism growth GO:0040018 55 30 2,000 5,404E-04 8,921E-03 ! tissue homeostasis GO:0001894 50 30 2,000 5,404E-04 8,861E-03 GO:0048871|multicellular organismal homeostasis, ! cell cycle checkpoint GO:0000075 145 71 3,000 5,697E-04 9,279E-03 ! prostate gland development GO:0030850 14 7 1,000 5,804E-04 9,389E-03 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 5,804E-04 9,328E-03 ! oxaloacetate metabolic process GO:0006107 13 7 1,000 5,804E-04 9,267E-03 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 5,804E-04 9,207E-03 ! positive regulation of heart rate GO:0010460 11 7 1,000 5,804E-04 9,147E-03 ! induction of apoptosis by oxidative stress GO:0008631 9 7 1,000 5,804E-04 9,089E-03 ! regulation of granule cell precursor proliferation GO:0021936 12 7 1,000 5,804E-04 9,031E-03 GO:0021940|positive regulation of granule cell precursor proliferation, ! phasic smooth muscle contraction GO:0014821 12 7 1,000 5,804E-04 8,973E-03 ! melanosome organization GO:0032438 10 7 1,000 5,804E-04 8,917E-03 ! male sex determination GO:0030238 15 7 1,000 5,804E-04 8,861E-03 ! negative regulation of DNA recombination GO:0045910 16 7 1,000 5,804E-04 8,806E-03 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 5,804E-04 8,752E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 5,804E-04 8,698E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 5,804E-04 8,645E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 5,804E-04 8,593E-03 ! diuresis GO:0030146 12 7 1,000 5,804E-04 8,541E-03 GO:0030147|natriuresis, ! negative regulation of nucleotide metabolic process GO:0045980 13 7 1,000 5,804E-04 8,49E-03 ! iron ion homeostasis GO:0055072 60 31 2,000 5,96E-04 8,667E-03 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 5,96E-04 8,616E-03 ! eye morphogenesis GO:0048592 65 31 2,000 5,96E-04 8,565E-03 ! carbohydrate transport GO:0008643 114 72 3,000 6,008E-04 8,583E-03 ! hexose biosynthetic process GO:0019319 53 32 2,000 6,551E-04 9,305E-03 ! regulation of caspase activity GO:0043281 136 74 3,000 6,664E-04 9,41E-03 ! regulation of pH GO:0006885 56 33 2,000 7,178E-04 0,01007834 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 7,711E-04 0,01076456 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 1,000 7,711E-04 0,0107034 GO:0016446|somatic hypermutation of immunoglobulin genes, ! succinate metabolic process GO:0006105 17 8 1,000 7,711E-04 0,01064293 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 7,711E-04 0,01058314 ! inositol phosphate-mediated signaling GO:0048016 11 8 1,000 7,711E-04 0,01052401 ! pigment granule organization GO:0048753 17 8 1,000 7,711E-04 0,01046555 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 7,711E-04 0,01040772 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 1,000 7,711E-04 0,01035054 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 7,711E-04 0,01029398 ! regulation of muscle hypertrophy GO:0014743 12 8 1,000 7,711E-04 0,01023803 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 7,711E-04 0,01018269 ! positive regulation of insulin secretion GO:0032024 17 8 1,000 7,711E-04 0,01012795 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 7,711E-04 0,01007379 ! multicellular organismal aging GO:0010259 20 8 1,000 7,711E-04 0,0100202 ! response to tumor cell GO:0002347 16 8 1,000 7,711E-04 9,967E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 7,711E-04 9,915E-03 ! positive regulation of smooth muscle contraction GO:0045987 15 8 1,000 7,711E-04 9,863E-03 ! regulation of endopeptidase activity GO:0052548 141 77 3,000 7,741E-04 9,85E-03 ! negative regulation of secretion GO:0051048 68 35 2,000 8,544E-04 0,01081498 ! negative regulation of DNA metabolic process GO:0051053 65 35 2,000 8,544E-04 0,01075923 ! calcium-mediated signaling GO:0019722 67 35 2,000 8,544E-04 0,01070405 ! activation of protein kinase activity GO:0032147 170 80 3,000 8,936E-04 0,01113802 ! regulation of proteolysis GO:0030162 77 36 2,000 9,284E-04 0,01151359 ! monosaccharide biosynthetic process GO:0046364 57 36 2,000 9,284E-04 0,01145544 ! response to hypoxia GO:0001666 178 81 3,000 9,361E-04 0,01149251 ! regulation of peptidase activity GO:0052547 150 82 3,000 9,801E-04 0,011972 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 9,879E-04 0,01200772 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 1,000 9,879E-04 0,01194828 GO:0010469|regulation of receptor activity, ! regulation of activated T cell proliferation GO:0046006 19 9 1,000 9,879E-04 0,01188942 ! regulation of glycolysis GO:0006110 20 9 1,000 9,879E-04 0,01183114 ! microtubule bundle formation GO:0001578 22 9 1,000 9,879E-04 0,01177342 ! retinol metabolic process GO:0042572 20 9 1,000 9,879E-04 0,01171627 ! establishment of melanosome localization GO:0032401 14 9 1,000 9,879E-04 0,01165967 ! renal water homeostasis GO:0003091 15 9 1,000 9,879E-04 0,01160362 ! regulation of telomere maintenance GO:0032204 17 9 1,000 9,879E-04 0,0115481 ! regulation of muscle adaptation GO:0043502 14 9 1,000 9,879E-04 0,01149311 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 2,000 1,006E-03 0,0116526 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 1,006E-03 0,01159764 ! response to oxygen levels GO:0070482 183 83 3,000 1,025E-03 0,01176192 ! glycogen metabolic process GO:0005977 63 38 2,000 1,088E-03 0,01242549 ! negative regulation of transport GO:0051051 164 85 3,000 1,121E-03 0,01273396 ! negative regulation of growth GO:0045926 168 85 3,000 1,121E-03 0,01267501 ! carbohydrate homeostasis GO:0033500 59 39 2,000 1,175E-03 0,01322319 GO:0042593|glucose homeostasis, ! glucan metabolic process GO:0044042 64 39 2,000 1,175E-03 0,01316254 GO:0006073|cellular glucan metabolic process, ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 1,000 1,231E-03 0,0137278 ! regulation of developmental growth GO:0048638 16 10 1,000 1,231E-03 0,0136654 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,231E-03 0,01360357 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,231E-03 0,01354229 ! positive regulation of heart contraction GO:0045823 17 10 1,000 1,231E-03 0,01348157 ! glucan biosynthetic process GO:0009250 14 10 1,000 1,231E-03 0,01342138 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 1,000 1,231E-03 0,01336173 GO:0006600|creatine metabolic process, ! lens development in camera-type eye GO:0002088 17 10 1,000 1,231E-03 0,01330261 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 1,231E-03 0,013244 ! motor axon guidance GO:0008045 22 10 1,000 1,231E-03 0,01318592 ! protein heterooligomerization GO:0051291 17 10 1,000 1,231E-03 0,01312834 ! regulation of gliogenesis GO:0014013 23 10 1,000 1,231E-03 0,01307126 GO:0045685|regulation of glial cell differentiation, ! melanosome localization GO:0032400 16 10 1,000 1,231E-03 0,01301467 ! multicellular organismal water homeostasis GO:0050891 16 10 1,000 1,231E-03 0,01295857 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 1,231E-03 0,01290296 GO:0043470|regulation of carbohydrate catabolic process, ! establishment of pigment granule localization GO:0051905 18 10 1,000 1,231E-03 0,01284782 ! tube morphogenesis GO:0035239 194 89 3,000 1,329E-03 0,0138191 ! regulation of hormone secretion GO:0046883 69 41 2,000 1,359E-03 0,01407204 ! monovalent inorganic cation homeostasis GO:0055067 72 41 2,000 1,359E-03 0,01401267 ! regulation of cell cycle process GO:0010564 161 90 3,000 1,385E-03 0,01422089 ! ossification GO:0001503 205 91 3,000 1,443E-03 0,01475165 ! ear morphogenesis GO:0042471 64 42 2,000 1,458E-03 0,01484399 ! alcohol biosynthetic process GO:0046165 65 42 2,000 1,458E-03 0,0147824 ! regulation of intracellular protein transport GO:0033157 86 42 2,000 1,458E-03 0,01472131 ! regulation of T cell differentiation GO:0045580 78 42 2,000 1,458E-03 0,01466073 ! regulation of protein secretion GO:0050708 77 42 2,000 1,458E-03 0,01460064 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 1,499E-03 0,01494543 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,499E-03 0,01488468 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 1,499E-03 0,01482441 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 1,499E-03 0,01476464 ! negative regulation of proteolysis GO:0045861 25 11 1,000 1,499E-03 0,01470534 ! regulation of intracellular pH GO:0051453 21 11 1,000 1,499E-03 0,01464652 ! positive regulation of muscle contraction GO:0045933 19 11 1,000 1,499E-03 0,01458817 ! positive regulation of peptide secretion GO:0002793 24 11 1,000 1,499E-03 0,01453028 ! pigment granule localization GO:0051875 20 11 1,000 1,499E-03 0,01447285 ! vasoconstriction GO:0042310 20 11 1,000 1,499E-03 0,01441587 ! neuroblast proliferation GO:0007405 25 11 1,000 1,499E-03 0,01435933 ! apical protein localization GO:0045176 18 11 1,000 1,499E-03 0,01430324 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 1,000 1,499E-03 0,01424759 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oocyte development GO:0048599 20 11 1,000 1,499E-03 0,01419237 ! regulation of embryonic development GO:0045995 35 11 1,000 1,499E-03 0,01413757 ! bone development GO:0060348 206 92 3,000 1,503E-03 0,01411832 ! carbohydrate biosynthetic process GO:0016051 158 94 3,000 1,626E-03 0,01522371 ! negative regulation of protein complex disassembly GO:0043242 113 44 2,000 1,669E-03 0,01556521 ! regulation of T cell activation GO:0050863 175 96 3,000 1,757E-03 0,01632294 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 1,782E-03 0,01648636 ! keratinocyte differentiation GO:0030216 81 45 2,000 1,782E-03 0,01642415 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 1,000 1,792E-03 0,01646091 ! virus-host interaction GO:0019048 30 12 1,000 1,792E-03 0,01639926 ! hippocampus development GO:0021766 29 12 1,000 1,792E-03 0,01633807 ! immunoglobulin production during immune response GO:0002381 24 12 1,000 1,792E-03 0,01627733 ! histone acetylation GO:0016573 27 12 1,000 1,792E-03 0,01621705 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,792E-03 0,0161572 ! oocyte differentiation GO:0009994 21 12 1,000 1,792E-03 0,0160978 ! localization within membrane GO:0051668 26 12 1,000 1,792E-03 0,01603884 ! transcription initiation GO:0006352 171 97 3,000 1,825E-03 0,01627446 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 2,000 1,898E-03 0,01686534 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 1,898E-03 0,01680423 ! pigmentation GO:0043473 103 46 2,000 1,898E-03 0,01674357 ! cell growth GO:0016049 90 46 2,000 1,898E-03 0,01668334 ! positive regulation of protein transport GO:0051222 80 46 2,000 1,898E-03 0,01662354 ! cartilage condensation GO:0001502 22 13 1,000 2,111E-03 0,01841656 ! response to X-ray GO:0010165 28 13 1,000 2,111E-03 0,01835102 ! asymmetric protein localization GO:0008105 24 13 1,000 2,111E-03 0,01828595 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 2,111E-03 0,01822133 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of lymphocyte differentiation GO:0045619 92 49 2,000 2,277E-03 0,01959085 ! epidermal cell differentiation GO:0009913 87 50 2,000 2,413E-03 0,02068761 ! retina development in camera-type eye GO:0060041 28 14 1,000 2,454E-03 0,02096179 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 1,000 2,454E-03 0,02088876 ! regulation of heart rate GO:0002027 25 14 1,000 2,454E-03 0,02081623 ! bone mineralization GO:0030282 18 14 1,000 2,454E-03 0,0207442 ! regulation of cellular pH GO:0030641 27 14 1,000 2,454E-03 0,02067267 ! response to gamma radiation GO:0010332 30 14 1,000 2,454E-03 0,02060163 ! regulation of protein complex disassembly GO:0043244 127 52 2,000 2,7E-03 0,02259085 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 2,822E-03 0,02352645 ! regulation of mRNA processing GO:0050684 26 15 1,000 2,822E-03 0,02344643 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 2,822E-03 0,02336695 ! G1/S transition checkpoint GO:0031575 37 15 1,000 2,822E-03 0,02328801 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 2,822E-03 0,0232096 ! water homeostasis GO:0030104 28 15 1,000 2,822E-03 0,02313171 ! cAMP biosynthetic process GO:0006171 25 15 1,000 2,822E-03 0,02305435 ! cartilage development GO:0051216 99 53 2,000 2,851E-03 0,02321735 ! regulation of angiogenesis GO:0045765 125 54 2,000 3,007E-03 0,02440642 ! activation of phospholipase C activity GO:0007202 110 54 2,000 3,007E-03 0,02432561 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 111 55 2,000 3,168E-03 0,02554471 ! regulation of multicellular organism growth GO:0040014 90 55 2,000 3,168E-03 0,02546068 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,213E-03 0,02573941 ! positive regulation of cell size GO:0045793 29 16 1,000 3,213E-03 0,02565529 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 1,000 3,213E-03 0,02557173 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 1,000 3,213E-03 0,0254887 ! response to osmotic stress GO:0006970 27 16 1,000 3,213E-03 0,02540621 ! DNA replication initiation GO:0006270 28 16 1,000 3,213E-03 0,02532426 ! biomineral formation GO:0031214 22 16 1,000 3,213E-03 0,02524283 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 1,000 3,213E-03 0,02516192 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 3,213E-03 0,02508153 ! negative regulation of cytoskeleton organization GO:0051494 139 56 2,000 3,335E-03 0,02594418 ! regulation of phospholipase activity GO:0010517 113 57 2,000 3,506E-03 0,02719284 ! heart morphogenesis GO:0003007 105 57 2,000 3,506E-03 0,02710679 ! regulation of intracellular transport GO:0032386 108 57 2,000 3,506E-03 0,02702128 ! activation of MAPKK activity GO:0000186 43 17 1,000 3,629E-03 0,02788123 ! cardiac muscle tissue development GO:0048738 34 17 1,000 3,629E-03 0,02779383 ! genitalia development GO:0048806 32 17 1,000 3,629E-03 0,02770697 ! neutrophil chemotaxis GO:0030593 29 17 1,000 3,629E-03 0,02762066 ! branched chain family amino acid metabolic process GO:0009081 37 17 1,000 3,629E-03 0,02753488 ! negative regulation of hormone secretion GO:0046888 26 17 1,000 3,629E-03 0,02744963 ! regulation of muscle cell differentiation GO:0051147 36 17 1,000 3,629E-03 0,02736491 ! induction of apoptosis via death domain receptors GO:0008625 23 17 1,000 3,629E-03 0,02728071 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 3,629E-03 0,02719703 GO:0031114|regulation of microtubule depolymerization, ! cellular polysaccharide metabolic process GO:0044264 93 58 2,000 3,683E-03 0,02751678 ! positive regulation of organelle organization GO:0010638 108 58 2,000 3,683E-03 0,02743289 ! positive regulation of lipase activity GO:0060193 115 58 2,000 3,683E-03 0,0273495 ! limbic system development GO:0021761 40 18 1,000 4,069E-03 0,03012044 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 1,000 4,069E-03 0,03002944 GO:0050886|endocrine process, ! positive regulation of proteolysis GO:0045862 36 18 1,000 4,069E-03 0,02993899 ! response to retinoic acid GO:0032526 31 18 1,000 4,069E-03 0,02984909 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 4,069E-03 0,02975972 ! regulation of immunoglobulin production GO:0002637 49 18 1,000 4,069E-03 0,02967088 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 4,069E-03 0,02958258 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 4,069E-03 0,02949479 ! positive regulation of secretion GO:0051047 110 61 2,000 4,246E-03 0,03069149 ! camera-type eye development GO:0043010 126 61 2,000 4,246E-03 0,03060096 ! DNA damage response, signal transduction GO:0042770 136 62 2,000 4,445E-03 0,03193832 ! G1 phase of mitotic cell cycle GO:0000080 39 19 1,000 4,531E-03 0,03246459 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 4,531E-03 0,03236966 ! response to vitamin A GO:0033189 32 19 1,000 4,531E-03 0,03227529 ! neuromuscular junction development GO:0007528 43 19 1,000 4,531E-03 0,03218146 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 4,531E-03 0,03208818 ! peptide cross-linking GO:0018149 39 19 1,000 4,531E-03 0,03199544 ! cellular pigmentation GO:0033059 37 19 1,000 4,531E-03 0,03190324 ! vitamin transport GO:0051180 31 19 1,000 4,531E-03 0,03181156 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 1,000 4,531E-03 0,03172041 ! embryonic organ morphogenesis GO:0048562 34 19 1,000 4,531E-03 0,03162978 ! peptide hormone secretion GO:0030072 32 19 1,000 4,531E-03 0,03153967 ! regulation of mitosis GO:0007088 112 63 2,000 4,649E-03 0,03226671 GO:0051783|regulation of nuclear division, ! skeletal system morphogenesis GO:0048705 118 63 2,000 4,649E-03 0,0321753 ! integrin-mediated signaling pathway GO:0007229 160 64 2,000 4,859E-03 0,03353217 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 5,017E-03 0,03452855 ! protein amino acid acetylation GO:0006473 41 20 1,000 5,017E-03 0,03443156 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 5,017E-03 0,03433511 ! response to vitamin GO:0033273 36 20 1,000 5,017E-03 0,0342392 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 5,017E-03 0,03414383 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 38 20 1,000 5,017E-03 0,03404899 ! retinoid metabolic process GO:0001523 34 20 1,000 5,017E-03 0,03395467 GO:0016101|diterpenoid metabolic process, ! cellular response to unfolded protein GO:0034620 35 20 1,000 5,017E-03 0,03386087 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 1,000 5,017E-03 0,03376759 ! body fluid secretion GO:0007589 33 20 1,000 5,017E-03 0,03367482 ! peptide secretion GO:0002790 38 20 1,000 5,017E-03 0,03358256 ! cell-cell junction organization GO:0045216 43 20 1,000 5,017E-03 0,03349081 ! negative regulation of translation GO:0017148 32 20 1,000 5,017E-03 0,03339955 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 5,295E-03 0,0351543 ! hormone secretion GO:0046879 39 21 1,000 5,526E-03 0,03658741 ! lipid phosphorylation GO:0046834 43 21 1,000 5,526E-03 0,03648852 ! cAMP metabolic process GO:0046058 41 21 1,000 5,526E-03 0,03639017 ! C21-steroid hormone metabolic process GO:0008207 38 21 1,000 5,526E-03 0,03629235 ! smooth muscle contraction GO:0006939 48 21 1,000 5,526E-03 0,03619505 ! negative regulation of intracellular transport GO:0032387 44 21 1,000 5,526E-03 0,03609827 ! vitamin A metabolic process GO:0006776 35 21 1,000 5,526E-03 0,03600201 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 5,526E-03 0,03590626 ! regulation of lipase activity GO:0060191 137 68 2,000 5,755E-03 0,0372918 ! cellular hormone metabolic process GO:0034754 120 69 2,000 5,993E-03 0,03873358 ! lung development GO:0030324 165 69 2,000 5,993E-03 0,03863138 ! urogenital system development GO:0001655 149 69 2,000 5,993E-03 0,03852972 ! homeostasis of number of cells GO:0048872 131 69 2,000 5,993E-03 0,03842859 ! developmental maturation GO:0021700 128 69 2,000 5,993E-03 0,038328 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 6,058E-03 0,03864009 ! cellular response to starvation GO:0009267 37 22 1,000 6,058E-03 0,03853947 ! cell aging GO:0007569 48 22 1,000 6,058E-03 0,03843936 ! cytolysis GO:0019835 27 22 1,000 6,058E-03 0,03833978 ! renal system process GO:0003014 42 22 1,000 6,058E-03 0,03824071 ! G1 phase GO:0051318 44 22 1,000 6,058E-03 0,03814215 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 6,058E-03 0,0380441 ! positive regulation of B cell activation GO:0050871 42 22 1,000 6,058E-03 0,03794655 ! terpenoid metabolic process GO:0006721 40 22 1,000 6,058E-03 0,0378495 ! somatic diversification of immunoglobulins GO:0016445 55 22 1,000 6,058E-03 0,03775295 ! germ cell development GO:0007281 133 70 2,000 6,237E-03 0,03877308 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 6,487E-03 0,04022505 ! positive regulation of DNA replication GO:0045740 44 23 1,000 6,612E-03 0,04089171 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 1,000 6,612E-03 0,04078845 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 6,612E-03 0,04068571 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 1,000 6,612E-03 0,04058348 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 6,612E-03 0,04048177 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 1,000 6,612E-03 0,04038056 ! hormone transport GO:0009914 41 23 1,000 6,612E-03 0,04027987 ! respiratory tube development GO:0030323 171 72 2,000 6,743E-03 0,04097992 ! B cell activation GO:0042113 179 72 2,000 6,743E-03 0,04087824 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 1,000 7,188E-03 0,04346374 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 1,000 7,188E-03 0,04335643 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 1,000 7,188E-03 0,04324964 ! positive regulation of cytoskeleton organization GO:0051495 52 24 1,000 7,188E-03 0,04314337 ! sex determination GO:0007530 48 24 1,000 7,188E-03 0,04303763 ! membrane depolarization GO:0051899 45 24 1,000 7,188E-03 0,0429324 ! pallium development GO:0021543 56 24 1,000 7,188E-03 0,04282769 ! oogenesis GO:0048477 44 24 1,000 7,188E-03 0,04272349 ! negative regulation of catabolic process GO:0009895 52 24 1,000 7,188E-03 0,04261979 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 7,188E-03 0,04251659 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 2,000 7,273E-03 0,04291789 ! respiratory system development GO:0060541 175 74 2,000 7,273E-03 0,04281447 ! regulation of transcription factor activity GO:0051090 137 75 2,000 7,547E-03 0,04431966 GO:0090046|regulation of transcription regulator activity, ! reproductive structure development GO:0048608 131 75 2,000 7,547E-03 0,04421338 ! phosphoinositide-mediated signaling GO:0048015 141 75 2,000 7,547E-03 0,0441076 ! eye development GO:0001654 155 75 2,000 7,547E-03 0,04400234 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 7,785E-03 0,04528554 ! dicarboxylic acid metabolic process GO:0043648 48 25 1,000 7,785E-03 0,04517798 ! keratinization GO:0031424 37 25 1,000 7,785E-03 0,04507092 ! negative regulation of DNA replication GO:0008156 45 25 1,000 7,785E-03 0,04496437 ! regulation of insulin secretion GO:0050796 42 25 1,000 7,785E-03 0,04485832 ! interaction with host GO:0051701 66 25 1,000 7,785E-03 0,04475277 ! immunoglobulin production GO:0002377 62 25 1,000 7,785E-03 0,04464772 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 1,000 7,785E-03 0,04454316 ! cell-matrix adhesion GO:0007160 181 76 2,000 7,827E-03 0,04467448 ! regulation of actin cytoskeleton organization GO:0032956 167 76 2,000 7,827E-03 0,04457034 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 1,000 8,405E-03 0,04775198 ! myelination GO:0042552 50 26 1,000 8,405E-03 0,04764119 ! molting cycle process GO:0022404 52 26 1,000 8,405E-03 0,04753091 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of smooth muscle contraction GO:0006940 48 26 1,000 8,405E-03 0,04742114 ! digestive system process GO:0022600 49 26 1,000 8,405E-03 0,04731187 ! neural crest cell development GO:0014032 59 26 1,000 8,405E-03 0,04720311 GO:0014033|neural crest cell differentiation, ! somatic diversification of immune receptors GO:0002200 63 26 1,000 8,405E-03 0,04709484 ! positive regulation of JUN kinase activity GO:0043507 59 26 1,000 8,405E-03 0,04698707 ! blood coagulation GO:0007596 151 79 2,000 8,703E-03 0,04854068 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 2,000 8,703E-03 0,04843011 ! protein oligomerization GO:0051259 149 79 2,000 8,703E-03 0,04832004 ! regulation of synaptic transmission GO:0050804 159 79 2,000 8,703E-03 0,04821048 ! negative regulation of organelle organization GO:0010639 181 80 2,000 9,007E-03 0,04978305 ! negative regulation of actin filament depolymerization GO:0030835 63 27 1,000 9,046E-03 0,04988493 ! iron ion transport GO:0006826 65 27 1,000 9,046E-03 0,04977258 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 1,000 9,046E-03 0,04966073 ! mitochondrial membrane organization GO:0007006 60 27 1,000 9,046E-03 0,04954938 ! response to starvation GO:0042594 47 27 1,000 9,046E-03 0,04943853 ! regulation of chromosome organization GO:0033044 49 27 1,000 9,046E-03 0,04932818 ! cellular response to nutrient levels GO:0031669 45 27 1,000 9,046E-03 0,04921832 ! fat-soluble vitamin metabolic process GO:0006775 42 27 1,000 9,046E-03 0,04910894 ! meiosis GO:0007126 143 81 2,000 9,317E-03 0,05047109 GO:0051327|M phase of meiotic cell cycle, ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 2,000 9,317E-03 0,05035942 ! cell-substrate adhesion GO:0031589 189 82 2,000 9,634E-03 0,0519557 ! protein import into nucleus GO:0006606 174 82 2,000 9,634E-03 0,05184126 ! meiotic cell cycle GO:0051321 144 82 2,000 9,634E-03 0,05172732 ! protein amino acid acylation GO:0043543 59 28 1,000 9,708E-03 0,05200955 ! dendrite development GO:0016358 67 28 1,000 9,708E-03 0,05189575 ! negative regulation of protein modification process GO:0031400 66 28 1,000 9,708E-03 0,05178244 ! fat cell differentiation GO:0045444 57 28 1,000 9,708E-03 0,05166962 ! base-excision repair GO:0006284 41 28 1,000 9,708E-03 0,0515573 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 1,000 9,708E-03 0,05144546 ! regulation of systemic arterial blood pressure GO:0003073 55 28 1,000 9,708E-03 0,0513341 ! regulation of JUN kinase activity GO:0043506 67 28 1,000 9,708E-03 0,05122323 ! response to drug GO:0042493 149 83 2,000 9,957E-03 0,05242366 ! nuclear import GO:0051170 177 83 2,000 9,957E-03 0,05231092 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 0,01039081 0,05447373 ! respiratory gaseous exchange GO:0007585 61 29 1,000 0,01039081 0,05435708 ! regulation of peptide secretion GO:0002791 52 29 1,000 0,01039081 0,05424093 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 1,000 0,01039081 0,05412528 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 1,000 0,01039081 0,05401012 ! somitogenesis GO:0001756 52 29 1,000 0,01039081 0,05389545 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 0,01039081 0,05378127 ! hemostasis GO:0007599 165 85 2,000 0,01062122 0,05485757 ! regulation of neuron differentiation GO:0045664 187 85 2,000 0,01062122 0,05474184 ! regulation of transmission of nerve impulse GO:0051969 167 85 2,000 0,01062122 0,0546266 ! regulation of actin filament depolymerization GO:0030834 67 30 1,000 0,01109441 0,05694043 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 1,000 0,01109441 0,05682106 ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 0,01109441 0,05670219 GO:0043433|negative regulation of transcription factor activity, ! peptide transport GO:0015833 60 31 1,000 0,01181844 0,0602765 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 0,01181844 0,06015092 ! ensheathment of neurons GO:0007272 64 31 1,000 0,01181844 0,06002587 GO:0008366|axon ensheathment, ! response to heat GO:0009408 54 31 1,000 0,01181844 0,05990134 ! regulation of DNA binding GO:0051101 167 89 2,000 0,01202545 0,06082439 ! protein localization in nucleus GO:0034504 192 89 2,000 0,01202545 0,06069872 ! regulation of neurological system process GO:0031644 175 89 2,000 0,01202545 0,06057356 ! positive regulation of protein modification process GO:0031401 156 90 2,000 0,01239235 0,06229323 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 1,000 0,01256266 0,06301966 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 1,000 0,01256266 0,06289053 ! response to mechanical stimulus GO:0009612 60 32 1,000 0,01256266 0,06276192 ! peripheral nervous system development GO:0007422 68 32 1,000 0,01256266 0,06263383 ! gland development GO:0048732 220 91 2,000 0,01276562 0,0635161 ! regulation of cell adhesion GO:0030155 241 92 2,000 0,01314527 0,06527215 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 0,01332684 0,06603951 ! response to ionizing radiation GO:0010212 74 33 1,000 0,01332684 0,06590582 ! leukocyte chemotaxis GO:0030595 55 33 1,000 0,01332684 0,06577268 GO:0060326|cell chemotaxis, ! negative regulation of protein transport GO:0051224 74 33 1,000 0,01332684 0,06564007 ! establishment of vesicle localization GO:0051650 67 33 1,000 0,01332684 0,065508 ! regulation of membrane potential GO:0042391 179 94 2,000 0,01392379 0,06830488 ! spliceosome assembly GO:0000245 75 34 1,000 0,01411076 0,06908332 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,01411076 0,06894516 ! sex differentiation GO:0007548 171 96 2,000 0,01472803 0,07181751 ! DNA damage checkpoint GO:0000077 78 35 1,000 0,01491417 0,07258033 ! regulation of synaptic plasticity GO:0048167 78 35 1,000 0,01491417 0,07243603 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 0,01491417 0,07229231 ! telencephalon development GO:0021537 81 35 1,000 0,01491417 0,07214915 ! placenta development GO:0001890 53 35 1,000 0,01491417 0,07200657 ! vesicle localization GO:0051648 70 35 1,000 0,01491417 0,07186454 ! regulation of muscle development GO:0048634 82 36 1,000 0,01573686 0,07567944 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 1,000 0,01573686 0,07553076 ! negative regulation of DNA binding GO:0043392 67 36 1,000 0,01573686 0,07538266 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 0,01573686 0,07523514 ! embryonic organ development GO:0048568 67 36 1,000 0,01573686 0,07508819 ! skeletal muscle tissue development GO:0007519 223 100 2,000 0,016414 0,07816649 GO:0060538|skeletal muscle organ development, ! hormone metabolic process GO:0042445 171 100 2,000 0,016414 0,07801441 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,0165786 0,07864374 ! cell junction organization GO:0034330 96 37 1,000 0,0165786 0,07849133 ! hormone biosynthetic process GO:0042446 62 37 1,000 0,0165786 0,07833951 ! regulation of microtubule-based process GO:0032886 86 37 1,000 0,0165786 0,07818827 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 0,01743917 0,08208841 ! meiosis I GO:0007127 74 38 1,000 0,01743917 0,08193055 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 1,000 0,01743917 0,08177329 ! DNA integrity checkpoint GO:0031570 82 38 1,000 0,01743917 0,08161664 ! cyclic nucleotide metabolic process GO:0009187 69 38 1,000 0,01743917 0,08146058 ! regulation of protein stability GO:0031647 77 38 1,000 0,01743917 0,08130512 ! negative regulation of binding GO:0051100 71 39 1,000 0,01831833 0,08524132 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 0,01831833 0,08507926 ! isoprenoid metabolic process GO:0006720 70 39 1,000 0,01831833 0,08491782 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,01831833 0,08475699 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 93 40 1,000 0,01921589 0,0887418 ! learning GO:0007612 82 40 1,000 0,01921589 0,08857436 ! development of primary female sexual characteristics GO:0046545 80 40 1,000 0,01921589 0,08840755 GO:0046660|female sex differentiation, ! mismatch repair GO:0006298 58 40 1,000 0,01921589 0,08824137 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,01921589 0,08807582 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 1,000 0,0201316 0,0921002 ! cellular amide metabolic process GO:0043603 73 41 1,000 0,0201316 0,09192805 ! multicellular organismal metabolic process GO:0044236 64 41 1,000 0,0201316 0,09175655 ! mesenchymal cell development GO:0014031 94 41 1,000 0,0201316 0,09158568 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 1,000 0,02106527 0,09565512 ! T cell differentiation GO:0030217 93 42 1,000 0,02106527 0,09547766 ! dorsal/ventral pattern formation GO:0009953 75 42 1,000 0,02106527 0,09530085 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,02201667 0,09942094 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 1,000 0,02201667 0,09923751 ! regulation of tube size GO:0035150 76 43 1,000 0,02201667 0,09905475 GO:0050880|regulation of blood vessel size, ! segmentation GO:0035282 78 43 1,000 0,02201667 0,09887267 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 1,000 0,02298559 0,10303451 ! double-strand break repair GO:0006302 85 44 1,000 0,02298559 0,1028458 ! B cell differentiation GO:0030183 124 45 1,000 0,02397183 0,10706248 ! female gamete generation GO:0007292 71 45 1,000 0,02397183 0,10686711 ! developmental growth GO:0048589 88 45 1,000 0,02397183 0,10667245 ! leukocyte migration GO:0050900 75 46 1,000 0,02497516 0,11093513 ! negative regulation of cell migration GO:0030336 122 46 1,000 0,02497516 0,1107338 ! polysaccharide biosynthetic process GO:0000271 79 46 1,000 0,02497516 0,11053319 ! regulation of JNK cascade GO:0046328 104 47 1,000 0,02599539 0,11484039 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02630699 0,11600717 ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02630699 0,11579814 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02630699 0,11558987 ! neuron fate determination GO:0048664 7 5 0,000 0,02630699 0,11538235 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02630699 0,11517557 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02630699 0,11496953 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02630699 0,11476423 ! polyol transport GO:0015791 12 5 0,000 0,02630699 0,11455966 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02630699 0,11435582 ! response to superoxide GO:0000303 10 5 0,000 0,02630699 0,1141527 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02630699 0,1139503 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02630699 0,11374862 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02630699 0,11354765 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02630699 0,11334739 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02630699 0,11314783 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02630699 0,11294898 ! hypothalamus development GO:0021854 9 5 0,000 0,02630699 0,11275082 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02630699 0,11255336 ! cobalt ion transport GO:0006824 11 5 0,000 0,02630699 0,11235659 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02630699 0,11216051 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02630699 0,1119651 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02630699 0,11177038 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02630699 0,11157634 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02630699 0,11138296 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02630699 0,11119026 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02630699 0,11099822 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02630699 0,11080684 ! transposition GO:0032196 9 5 0,000 0,02630699 0,11061613 ! negative chemotaxis GO:0050919 16 5 0,000 0,02630699 0,11042607 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02630699 0,11023665 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02630699 0,11004789 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02630699 0,10985978 ! behavioral response to pain GO:0048266 10 5 0,000 0,02630699 0,1096723 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02630699 0,10948547 ! Notch receptor processing GO:0007220 11 5 0,000 0,02630699 0,10929927 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02630699 0,1091137 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02630699 0,10892876 ! micturition GO:0060073 9 5 0,000 0,02630699 0,10874445 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02630699 0,10856076 ! copulation GO:0007620 9 5 0,000 0,02630699 0,10837769 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02630699 0,10819524 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02630699 0,10801339 ! bioluminescence GO:0008218 9 5 0,000 0,02630699 0,10783216 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02630699 0,10765154 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02630699 0,10747152 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02630699 0,1072921 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02630699 0,10711328 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02630699 0,10693506 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02630699 0,10675743 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02630699 0,10658038 ! grooming behavior GO:0007625 6 5 0,000 0,02630699 0,10640392 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02630699 0,10622805 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02630699 0,10605276 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02630699 0,10587804 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02630699 0,1057039 ! response to protozoan GO:0001562 13 5 0,000 0,02630699 0,10553033 ! lymph vessel development GO:0001945 10 5 0,000 0,02630699 0,10535733 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02630699 0,10518489 ! endochondral ossification GO:0001958 17 5 0,000 0,02630699 0,10501302 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02630699 0,10484171 ! single strand break repair GO:0000012 8 5 0,000 0,02630699 0,10467096 ! parathyroid gland development GO:0060017 14 5 0,000 0,02630699 0,10450076 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02630699 0,10433112 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02630699 0,10416203 ! cytokine secretion GO:0050663 15 5 0,000 0,02630699 0,10399348 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02630699 0,10382548 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02630699 0,10365802 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02630699 0,10349109 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02630699 0,10332471 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02630699 0,10315886 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02630699 0,10299354 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02630699 0,10282875 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02630699 0,10266449 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02630699 0,10250075 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02630699 0,10233753 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02630699 0,10217483 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02630699 0,10201265 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02630699 0,10185098 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02630699 0,10168983 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02630699 0,10152918 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02630699 0,10136904 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02630699 0,1012094 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02630699 0,10105027 ! polyol catabolic process GO:0046174 9 5 0,000 0,02630699 0,10089163 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02630699 0,1007335 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02630699 0,10057585 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02630699 0,1004187 ! mitochondrial fission GO:0000266 8 5 0,000 0,02630699 0,10026204 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02630699 0,10010587 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02630699 0,09995019 ! mRNA transcription GO:0009299 10 5 0,000 0,02630699 0,09979498 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02630699 0,09964026 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02630699 0,09948602 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02630699 0,09933226 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02630699 0,09917897 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02630699 0,09902615 ! monocyte activation GO:0042117 10 5 0,000 0,02630699 0,0988738 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02630699 0,09872192 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02630699 0,09857051 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02630699 0,09841956 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02630699 0,09826907 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02630699 0,09811904 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02630699 0,09796947 ! forebrain neuron development GO:0021884 13 5 0,000 0,02630699 0,09782035 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02630699 0,09767169 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02630699 0,09752347 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02630699 0,09737571 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02630699 0,0972284 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02630699 0,09708153 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02630699 0,0969351 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02630699 0,09678911 ! lipid glycosylation GO:0030259 7 5 0,000 0,02630699 0,09664356 ! nucleobase transport GO:0015851 6 5 0,000 0,02630699 0,09649845 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02630699 0,09635378 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02630699 0,09620954 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02630699 0,09606572 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02630699 0,09592234 ! basic amino acid transport GO:0015802 12 5 0,000 0,02630699 0,09577939 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02630699 0,09563686 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02630699 0,09549475 ! actin nucleation GO:0045010 11 5 0,000 0,02630699 0,09535307 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02630699 0,09521181 ! depurination GO:0045007 5 5 0,000 0,02630699 0,09507096 ! depyrimidination GO:0045008 10 5 0,000 0,02630699 0,09493053 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02630699 0,09479052 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02630699 0,09465091 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02630699 0,09451172 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02630699 0,09437294 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02630699 0,09423456 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,02630699 0,09409659 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02630699 0,09395902 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02630699 0,09382185 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02630699 0,09368509 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02630699 0,09354872 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02630699 0,09341275 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02630699 0,09327717 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02630699 0,09314199 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02630699 0,09300719 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02630699 0,09287279 ! response to arsenic GO:0046685 11 5 0,000 0,02630699 0,09273877 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02630699 0,09260514 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02630699 0,0924719 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02630699 0,09233904 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02630699 0,09220656 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02630699 0,09207446 ! response to mercury ion GO:0046689 8 5 0,000 0,02630699 0,09194273 ! response to cadmium ion GO:0046686 7 5 0,000 0,02630699 0,09181139 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02630699 0,09168041 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02630699 0,09154981 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02630699 0,09141959 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02630699 0,09128973 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02630699 0,09116024 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02630699 0,09103112 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02630699 0,09090236 ! decidualization GO:0046697 11 5 0,000 0,02630699 0,09077397 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02630699 0,09064594 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02630699 0,09051827 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02630699 0,09039096 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02630699 0,090264 ! embryonic cleavage GO:0040016 6 5 0,000 0,02630699 0,09013741 ! peroxisome fission GO:0016559 5 5 0,000 0,02630699 0,09001116 ! histone demethylation GO:0016577 13 5 0,000 0,02630699 0,08988527 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02630699 0,08975973 ! mitotic recombination GO:0006312 9 5 0,000 0,02630699 0,08963455 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02630699 0,08950971 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02630699 0,08938522 ! metaphase plate congression GO:0051310 7 5 0,000 0,02630699 0,08926107 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02630699 0,08913727 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02630699 0,08901381 ! enteric nervous system development GO:0048484 8 5 0,000 0,02630699 0,08889069 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02630699 0,08876791 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02630699 0,08864548 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02630699 0,08852337 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02630699 0,08840161 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02630699 0,08828018 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02630699 0,08815908 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02630699 0,08803831 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02630699 0,08791788 ! metaphase GO:0051323 11 5 0,000 0,02630699 0,08779777 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02630699 0,08767799 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02630699 0,08755854 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02630699 0,08743941 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02630699 0,08732061 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02630699 0,08720213 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02630699 0,08708397 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02630699 0,08696613 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02630699 0,08684861 ! response to redox state GO:0051775 6 5 0,000 0,02630699 0,0867314 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02630699 0,08661451 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02630699 0,08649794 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02630699 0,08638168 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02630699 0,08626573 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02630699 0,08615009 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02630699 0,08603477 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02630699 0,08591975 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02630699 0,08580503 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02630699 0,08569063 ! striatum development GO:0021756 14 5 0,000 0,02630699 0,08557652 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02630699 0,08546273 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02630699 0,08534923 ! glial cell migration GO:0008347 10 5 0,000 0,02630699 0,08523603 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02630699 0,08512314 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02630699 0,08501054 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02630699 0,08489824 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02630699 0,08478624 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02630699 0,08467453 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02630699 0,08456312 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02630699 0,084452 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02630699 0,08434117 ! neuroprotection GO:0043526 8 5 0,000 0,02630699 0,08423063 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02630699 0,08412038 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02630699 0,08401042 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02630699 0,08390074 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02630699 0,08379136 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02630699 0,08368225 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02630699 0,08357343 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02630699 0,0834649 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02630699 0,08335664 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02630699 0,08324867 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02630699 0,08314097 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02630699 0,08303355 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02630699 0,08292641 ! spindle assembly GO:0051225 6 5 0,000 0,02630699 0,08281955 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02630699 0,08271296 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02630699 0,08260665 ! protein palmitoylation GO:0018345 12 5 0,000 0,02630699 0,0825006 ! drug metabolic process GO:0017144 7 5 0,000 0,02630699 0,08239483 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02630699 0,08228933 ! organ regeneration GO:0031100 7 5 0,000 0,02630699 0,0821841 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02630699 0,08207914 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02630699 0,08197445 ! mitochondrial transport GO:0006839 94 48 1,000 0,02703231 0,08412729 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 0,02703231 0,08402026 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 1,000 0,02703231 0,0839135 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,02703231 0,08380701 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,02703231 0,08370079 ! JAK-STAT cascade GO:0007259 82 48 1,000 0,02703231 0,08359484 ! response to calcium ion GO:0051592 94 49 1,000 0,0280857 0,08674257 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,0280857 0,08663305 ! regulation of action potential GO:0001508 102 50 1,000 0,02915538 0,08981917 ! induction of apoptosis by extracellular signals GO:0008624 99 50 1,000 0,02915538 0,08970604 ! immunoglobulin mediated immune response GO:0016064 89 50 1,000 0,02915538 0,08959321 GO:0019724|B cell mediated immunity, ! response to temperature stimulus GO:0009266 84 51 1,000 0,03024114 0,09281295 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,03024114 0,0926965 ! positive regulation of binding GO:0051099 88 52 1,000 0,03134278 0,09595289 ! excretion GO:0007588 87 52 1,000 0,03134278 0,0958328 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 0,03134278 0,09571301 ! histone modification GO:0016570 104 52 1,000 0,03134278 0,09559352 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 1,000 0,03134278 0,09547433 ! ribonucleoprotein complex assembly GO:0022618 104 52 1,000 0,03134278 0,09535543 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03148519 0,09566954 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03148519 0,09555069 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03148519 0,09543214 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03148519 0,09531389 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03148519 0,09519593 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03148519 0,09507825 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03148519 0,09496087 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03148519 0,09484378 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03148519 0,09472698 ! response to oxygen radical GO:0000305 11 6 0,000 0,03148519 0,09461046 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03148519 0,09449424 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,03148519 0,09437829 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03148519 0,09426263 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03148519 0,09414726 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03148519 0,09403216 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03148519 0,09391735 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03148519 0,09380281 ! forebrain regionalization GO:0021871 9 6 0,000 0,03148519 0,09368856 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03148519 0,09357458 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03148519 0,09346088 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03148519 0,09334746 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03148519 0,09323431 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03148519 0,09312144 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03148519 0,09300884 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03148519 0,09289651 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03148519 0,09278445 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03148519 0,09267266 ! malate metabolic process GO:0006108 13 6 0,000 0,03148519 0,09256114 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03148519 0,09244989 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03148519 0,0923389 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03148519 0,09222819 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03148519 0,09211773 ! protein refolding GO:0042026 15 6 0,000 0,03148519 0,09200754 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03148519 0,09189762 ! opsonization GO:0008228 8 6 0,000 0,03148519 0,09178796 ! mating behavior GO:0007617 7 6 0,000 0,03148519 0,09167855 ! erythrocyte maturation GO:0043249 8 6 0,000 0,03148519 0,09156941 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,03148519 0,09146053 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03148519 0,09135191 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,03148519 0,09124354 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,03148519 0,09113544 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03148519 0,09102758 ! response to interferon-gamma GO:0034341 16 6 0,000 0,03148519 0,09091999 ! toxin metabolic process GO:0009404 11 6 0,000 0,03148519 0,09081264 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03148519 0,09070555 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,03148519 0,09059871 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,03148519 0,09049213 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,03148519 0,09038579 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03148519 0,0902797 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03148519 0,09017387 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03148519 0,09006828 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03148519 0,08996293 ! thymic T cell selection GO:0045061 16 6 0,000 0,03148519 0,08985784 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03148519 0,08975298 ! protein lipoylation GO:0009249 10 6 0,000 0,03148519 0,08964838 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03148519 0,08954401 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,03148519 0,08943989 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03148519 0,08933601 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,03148519 0,08923238 ! glutamate catabolic process GO:0006538 12 6 0,000 0,03148519 0,08912898 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03148519 0,08902582 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03148519 0,0889229 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,03148519 0,08882022 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03148519 0,08871777 ! hyperosmotic response GO:0006972 10 6 0,000 0,03148519 0,08861556 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,03148519 0,08851359 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03148519 0,08841185 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03148519 0,08831034 ! urea metabolic process GO:0019627 7 6 0,000 0,03148519 0,08820907 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03148519 0,08810803 ! neutrophil activation GO:0042119 7 6 0,000 0,03148519 0,08800722 ! regulation of appetite GO:0032098 10 6 0,000 0,03148519 0,08790664 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03148519 0,08780629 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,03148519 0,08770617 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03148519 0,08760627 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03148519 0,08750661 ! T cell mediated immunity GO:0002456 17 6 0,000 0,03148519 0,08740717 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03148519 0,08730795 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,03148519 0,08720897 ! carnitine transport GO:0015879 10 6 0,000 0,03148519 0,0871102 GO:0015838|betaine transport, ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03148519 0,08701166 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03148519 0,08691334 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,03148519 0,08681525 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,03148519 0,08671737 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03148519 0,08661972 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03148519 0,08652228 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,03148519 0,08642506 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,03148519 0,08632807 ! establishment of spindle localization GO:0051293 16 6 0,000 0,03148519 0,08623129 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03148519 0,08613472 ! neural nucleus development GO:0048857 19 6 0,000 0,03148519 0,08603838 ! response to UV-C GO:0010225 14 6 0,000 0,03148519 0,08594224 ! astrocyte development GO:0014002 16 6 0,000 0,03148519 0,08584633 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03148519 0,08575062 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03148519 0,08565513 ! interaction with symbiont GO:0051702 14 6 0,000 0,03148519 0,08555985 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03148519 0,08546479 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03148519 0,08536993 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,03148519 0,08527529 ! response to copper ion GO:0046688 10 6 0,000 0,03148519 0,08518085 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,03148519 0,08508662 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,03148519 0,08499261 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03148519 0,08489879 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,03148519 0,08480519 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03148519 0,08471179 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03148519 0,0846186 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03148519 0,08452561 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,03148519 0,08443283 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03148519 0,08434025 ! Schwann cell development GO:0014044 15 6 0,000 0,03148519 0,08424787 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03148519 0,0841557 ! response to pheromone GO:0019236 6 6 0,000 0,03148519 0,08406372 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,03148519 0,08397195 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,03148519 0,08388038 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,03148519 0,08378901 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,03148519 0,08369783 ! subpallium development GO:0021544 15 6 0,000 0,03148519 0,08360686 ! neural tube patterning GO:0021532 8 6 0,000 0,03148519 0,08351608 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03148519 0,0834255 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03148519 0,08333511 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03148519 0,08324492 ! G2 phase GO:0051319 16 6 0,000 0,03148519 0,08315493 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03148519 0,08306513 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03148519 0,08297552 ! oxygen homeostasis GO:0032364 10 6 0,000 0,03148519 0,08288611 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03148519 0,08279689 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03148519 0,08270786 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03148519 0,08261902 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03148519 0,08253037 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03148519 0,08244192 ! receptor internalization GO:0031623 11 6 0,000 0,03148519 0,08235365 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,03148519 0,08226557 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,03148519 0,08217768 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,03148519 0,08208998 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03148519 0,08200246 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,03148519 0,08191513 ! protein deubiquitination GO:0016579 16 6 0,000 0,03148519 0,08182799 ! protein destabilization GO:0031648 9 6 0,000 0,03148519 0,08174103 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03148519 0,08165425 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03148519 0,08156766 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03148519 0,08148126 ! regulation of viral transcription GO:0046782 11 6 0,000 0,03148519 0,08139503 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,03148519 0,08130899 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,03148519 0,08122313 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03148519 0,08113746 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03148519 0,08105196 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,03148519 0,08096664 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03148519 0,0808815 ! neural plate development GO:0001840 9 6 0,000 0,03148519 0,08079654 ! catecholamine transport GO:0051937 9 6 0,000 0,03148519 0,08071176 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,03148519 0,08062716 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03148519 0,08054273 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,03148519 0,08045848 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,03148519 0,08037441 ! maternal placenta development GO:0001893 12 6 0,000 0,03148519 0,08029051 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,03148519 0,08020679 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03148519 0,08012324 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,03148519 0,08003986 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03148519 0,07995666 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03148519 0,07987363 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,03148519 0,07979078 GO:0055081|anion homeostasis, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 1,000 0,0324601 0,08217619 ! vesicle organization GO:0016050 127 53 1,000 0,0324601 0,08209112 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,0324601 0,08200623 ! synapse organization GO:0050808 102 53 1,000 0,0324601 0,08192151 ! embryonic skeletal system development GO:0048706 101 54 1,000 0,03359291 0,08469296 ! regulation of muscle contraction GO:0006937 94 54 1,000 0,03359291 0,08460564 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 1,000 0,03359291 0,08451851 ! covalent chromatin modification GO:0016569 115 54 1,000 0,03359291 0,08443156 ! regulation of cell shape GO:0008360 142 54 1,000 0,03359291 0,08434478 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 1,000 0,03474101 0,08713787 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 1,000 0,03474101 0,0870485 ! cell maturation GO:0048469 107 55 1,000 0,03474101 0,08695931 ! negative regulation of cell motion GO:0051271 142 55 1,000 0,03474101 0,0868703 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,03590421 0,0896871 ! RNA elongation GO:0006354 90 56 1,000 0,03590421 0,08959549 ! tRNA transcription GO:0009304 17 7 0,000 0,03663599 0,09132829 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03663599 0,09123519 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03663599 0,09114228 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03663599 0,09104957 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03663599 0,09095704 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03663599 0,09086469 ! sleep GO:0030431 16 7 0,000 0,03663599 0,09077254 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03663599 0,09068057 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03663599 0,09058879 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03663599 0,09049719 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03663599 0,09040578 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03663599 0,09031455 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03663599 0,09022351 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03663599 0,09013265 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03663599 0,09004198 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03663599 0,08995148 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03663599 0,08986117 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03663599 0,08977104 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03663599 0,08968109 ! glycolipid transport GO:0046836 11 7 0,000 0,03663599 0,08959131 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03663599 0,08950172 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,03663599 0,08941231 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03663599 0,08932308 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03663599 0,08923402 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03663599 0,08914514 ! mRNA stabilization GO:0048255 18 7 0,000 0,03663599 0,08905644 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,03663599 0,08896792 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03663599 0,08887957 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03663599 0,08879139 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03663599 0,08870339 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03663599 0,08861557 ! lipoprotein transport GO:0042953 14 7 0,000 0,03663599 0,08852792 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03663599 0,08844044 ! rhythmic behavior GO:0007622 17 7 0,000 0,03663599 0,08835313 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03663599 0,088266 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03663599 0,08817904 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03663599 0,08809225 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03663599 0,08800563 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03663599 0,08791918 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03663599 0,0878329 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03663599 0,08774679 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03663599 0,08766085 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03663599 0,08757507 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03663599 0,08748947 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03663599 0,08740403 GO:0045911|positive regulation of DNA recombination, ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03663599 0,08731875 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03663599 0,08723365 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03663599 0,08714871 ! spinal cord patterning GO:0021511 14 7 0,000 0,03663599 0,08706393 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03663599 0,08697932 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03663599 0,08689488 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03663599 0,0868106 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03663599 0,08672648 ! adrenal gland development GO:0030325 17 7 0,000 0,03663599 0,08664252 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03663599 0,08655873 ! ovulation GO:0030728 10 7 0,000 0,03663599 0,0864751 ! adenohypophysis development GO:0021984 11 7 0,000 0,03663599 0,08639163 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03663599 0,08630832 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03663599 0,08622517 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03663599 0,08614218 ! microtubule nucleation GO:0007020 21 7 0,000 0,03663599 0,08605935 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03663599 0,08597668 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03663599 0,08589417 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03663599 0,08581182 ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03663599 0,08572962 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03663599 0,08564758 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03663599 0,0855657 ! galactose metabolic process GO:0006012 13 7 0,000 0,03663599 0,08548398 ! vesicle fusion GO:0006906 20 7 0,000 0,03663599 0,08540241 ! response to dietary excess GO:0002021 8 7 0,000 0,03663599 0,08532099 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03663599 0,08523974 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03663599 0,08515863 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03663599 0,08507768 GO:0046464|acylglycerol catabolic process, ! organ growth GO:0035265 15 7 0,000 0,03663599 0,08499689 ! nucleoside transport GO:0015858 11 7 0,000 0,03663599 0,08491625 ! nucleoside salvage GO:0043174 11 7 0,000 0,03663599 0,08483576 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03663599 0,08475542 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03663599 0,08467524 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! parturition GO:0007567 16 7 0,000 0,03663599 0,0845952 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03663599 0,08451532 ! rRNA modification GO:0000154 14 7 0,000 0,03663599 0,08443559 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03663599 0,08435601 ! spindle checkpoint GO:0031577 16 7 0,000 0,03663599 0,08427658 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,03663599 0,08419729 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03663599 0,08411816 ! monocyte differentiation GO:0030224 16 7 0,000 0,03663599 0,08403918 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03663599 0,08396034 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03663599 0,08388165 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03663599 0,08380311 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03663599 0,08372472 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03663599 0,08364647 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,03663599 0,08356837 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03663599 0,08349041 ! eating behavior GO:0042755 8 7 0,000 0,03663599 0,0834126 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03663599 0,08333494 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03663599 0,08325742 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03663599 0,08318004 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03663599 0,08310281 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03663599 0,08302572 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03663599 0,08294877 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03663599 0,08287197 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03663599 0,0827953 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03663599 0,08271878 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03663599 0,0826424 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03663599 0,08256617 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03663599 0,08249007 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03663599 0,08241411 ! histone ubiquitination GO:0016574 9 7 0,000 0,03663599 0,08233829 ! regulation of meiosis GO:0040020 12 7 0,000 0,03663599 0,08226261 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03663599 0,08218707 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03663599 0,08211167 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03663599 0,08203641 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03663599 0,08196129 ! transcription termination GO:0006353 14 7 0,000 0,03663599 0,0818863 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03663599 0,08181145 ! anaphase GO:0051322 18 7 0,000 0,03663599 0,08173673 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03663599 0,08166216 ! axonal fasciculation GO:0007413 19 7 0,000 0,03663599 0,08158772 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03663599 0,08151341 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03663599 0,08143924 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03663599 0,0813652 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03663599 0,0812913 ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03663599 0,08121754 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03663599 0,0811439 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03663599 0,0810704 ! antibiotic transport GO:0042891 9 7 0,000 0,03663599 0,08099704 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03663599 0,0809238 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03663599 0,0808507 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03663599 0,08077773 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03663599 0,08070489 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03663599 0,08063218 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03663599 0,08055961 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03663599 0,08048716 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03663599 0,08041485 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03663599 0,08034266 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03663599 0,0802706 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03663599 0,08019868 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03663599 0,08012688 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03663599 0,08005521 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03663599 0,07998367 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03663599 0,07991225 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03663599 0,07984097 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03663599 0,07976981 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03663599 0,07969877 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03663599 0,07962787 ! muscle adaptation GO:0043500 13 7 0,000 0,03663599 0,07955709 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03663599 0,07948643 ! retina homeostasis GO:0001895 12 7 0,000 0,03663599 0,0794159 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03663599 0,0793455 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03663599 0,07927522 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03663599 0,07920507 ! muscle fiber development GO:0048747 131 57 1,000 0,03708232 0,08009911 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,03708232 0,08002836 ! regulation of actin filament length GO:0030832 118 58 1,000 0,03827514 0,08252972 ! establishment of organelle localization GO:0051656 122 59 1,000 0,0394825 0,08505798 ! lipid modification GO:0030258 112 60 1,000 0,0407042 0,08761266 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,04175955 0,08980508 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,04175955 0,0897261 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,04175955 0,08964725 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04175955 0,08956854 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04175955 0,08948997 ! male meiosis GO:0007140 9 8 0,000 0,04175955 0,08941154 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,04175955 0,08933325 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,04175955 0,08925509 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,04175955 0,08917707 ! meiotic prophase I GO:0007128 14 8 0,000 0,04175955 0,08909919 ! response to zinc ion GO:0010043 12 8 0,000 0,04175955 0,08902144 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,04175955 0,08894383 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04175955 0,08886635 ! oligopeptide transport GO:0006857 16 8 0,000 0,04175955 0,08878901 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,04175955 0,0887118 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,04175955 0,08863473 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,04175955 0,08855779 ! signal peptide processing GO:0006465 12 8 0,000 0,04175955 0,08848098 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,04175955 0,08840431 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,04175955 0,08832777 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04175955 0,08825136 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,04175955 0,08817508 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,04175955 0,08809894 ! estrogen metabolic process GO:0008210 17 8 0,000 0,04175955 0,08802293 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,04175955 0,08794704 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04175955 0,08787129 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,04175955 0,08779567 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04175955 0,08772018 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04175955 0,08764482 ! reflex GO:0060004 17 8 0,000 0,04175955 0,08756959 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04175955 0,08749449 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,04175955 0,08741951 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,04175955 0,08734467 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,04175955 0,08726995 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,04175955 0,08719536 ! astrocyte differentiation GO:0048708 19 8 0,000 0,04175955 0,0871209 ! histidine catabolic process GO:0006548 10 8 0,000 0,04175955 0,08704656 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04175955 0,08697235 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,04175955 0,08689827 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,04175955 0,08682432 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,04175955 0,08675048 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,04175955 0,08667678 ! melanin metabolic process GO:0006582 17 8 0,000 0,04175955 0,0866032 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,04175955 0,08652975 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,04175955 0,08645642 ! macrophage activation GO:0042116 13 8 0,000 0,04175955 0,08638321 ! purine salvage GO:0043101 12 8 0,000 0,04175955 0,08631013 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,04175955 0,08623717 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04175955 0,08616433 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,04175955 0,08609162 ! osteoblast development GO:0002076 17 8 0,000 0,04175955 0,08601903 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,04175955 0,08594656 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,04175955 0,08587422 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,04175955 0,08580199 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,04175955 0,08572989 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04175955 0,08565791 ! response to UV-B GO:0010224 17 8 0,000 0,04175955 0,08558605 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,04175955 0,08551431 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04175955 0,08544269 ! intermediate filament organization GO:0045109 12 8 0,000 0,04175955 0,08537119 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,04175955 0,08529981 ! cellular extravasation GO:0045123 13 8 0,000 0,04175955 0,08522855 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,04175955 0,0851574 ! response to antibiotic GO:0046677 11 8 0,000 0,04175955 0,08508638 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,04175955 0,08501548 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,04175955 0,08494469 ! DNA topological change GO:0006265 12 8 0,000 0,04175955 0,08487402 ! response to tropane GO:0014073 15 8 0,000 0,04175955 0,08480347 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,04175955 0,08473303 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,04175955 0,08466271 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04175955 0,08459251 ! mast cell activation GO:0045576 14 8 0,000 0,04175955 0,08452243 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,04175955 0,08445246 ! gas homeostasis GO:0033483 14 8 0,000 0,04175955 0,08438261 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,04175955 0,08431287 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,04175955 0,08424325 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,04175955 0,08417374 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04175955 0,08410434 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04175955 0,08403507 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,04175955 0,0839659 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04175955 0,08389685 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,04175955 0,08382791 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,04175955 0,08375909 ! intracellular lipid transport GO:0032365 16 8 0,000 0,04175955 0,08369038 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04175955 0,08362178 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,04175955 0,08355329 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,04175955 0,08348492 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04175955 0,08341666 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,04175955 0,08334851 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,04175955 0,08328047 ! hormone catabolic process GO:0042447 17 8 0,000 0,04175955 0,08321254 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,04175955 0,08314472 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,04175955 0,08307701 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,04175955 0,08300941 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,04175955 0,08294193 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04175955 0,08287455 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,04175955 0,08280728 ! adult feeding behavior GO:0008343 10 8 0,000 0,04175955 0,08274012 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,04175955 0,08267307 ! ATP catabolic process GO:0006200 11 8 0,000 0,04175955 0,08260613 ! blastocyst growth GO:0001832 19 8 0,000 0,04175955 0,0825393 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04175955 0,08247257 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04175955 0,08240595 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,04175955 0,08233944 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04175955 0,08227304 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,04175955 0,08220674 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,04175955 0,08214056 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,04175955 0,08207447 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,04175955 0,0820085 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,04175955 0,08194263 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,04175955 0,08187686 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04175955 0,0818112 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,04175955 0,08174565 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04175955 0,0816802 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,04175955 0,08161486 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,04175955 0,08154962 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04175955 0,08148448 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,04175955 0,08141945 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,04175955 0,08135452 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,04175955 0,0812897 ! regulation of cellular component size GO:0032535 125 61 1,000 0,04194006 0,08157609 ! regulation of heart contraction GO:0008016 123 61 1,000 0,04194006 0,0815112 ! viral reproductive process GO:0022415 132 62 1,000 0,0431899 0,08387355 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,0431899 0,08380693 ! axon extension GO:0048675 16 9 0,000 0,046856 0,09084857 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,046856 0,09077652 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,046856 0,09070459 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,046856 0,09063278 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,046856 0,09056107 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,046856 0,09048948 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,046856 0,09041801 ! reproductive behavior GO:0019098 22 9 0,000 0,046856 0,09034664 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,046856 0,09027539 ! Golgi to endosome transport GO:0006895 25 9 0,000 0,046856 0,09020425 ! UTP metabolic process GO:0046051 10 9 0,000 0,046856 0,09013323 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,046856 0,09006231 ! induction of positive chemotaxis GO:0050930 17 9 0,000 0,046856 0,08999151 ! artery development GO:0060840 25 9 0,000 0,046856 0,08992081 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,046856 0,08985023 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,046856 0,08977976 ! equilibrioception GO:0050957 20 9 0,000 0,046856 0,0897094 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,046856 0,08963915 ! chemosensory behavior GO:0007635 21 9 0,000 0,046856 0,08956901 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,046856 0,08949898 ! leukocyte degranulation GO:0043299 16 9 0,000 0,046856 0,08942906 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,046856 0,08935925 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,046856 0,08928955 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,046856 0,08921995 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,046856 0,08915047 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,046856 0,08908109 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,046856 0,08901182 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,046856 0,08894266 ! protein targeting to ER GO:0045047 25 9 0,000 0,046856 0,0888736 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,046856 0,08880465 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,046856 0,08873581 ! T cell selection GO:0045058 27 9 0,000 0,046856 0,08866708 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,046856 0,08859845 ! glycine catabolic process GO:0006546 15 9 0,000 0,046856 0,08852993 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,046856 0,08846151 ! endosome organization GO:0007032 20 9 0,000 0,046856 0,0883932 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,046856 0,088325 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,046856 0,0882569 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,046856 0,0881889 ! mannose metabolic process GO:0006013 13 9 0,000 0,046856 0,08812101 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,046856 0,08805323 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,046856 0,08798555 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,046856 0,08791797 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,046856 0,0878505 ! receptor clustering GO:0043113 20 9 0,000 0,046856 0,08778313 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,046856 0,08771586 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,046856 0,0876487 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,046856 0,08758164 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,046856 0,08751468 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,046856 0,08744782 ! macrophage differentiation GO:0030225 15 9 0,000 0,046856 0,08738107 ! oligodendrocyte development GO:0014003 11 9 0,000 0,046856 0,08731441 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,046856 0,08724786 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,046856 0,08718141 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,046856 0,08711507 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,046856 0,08704882 ! response to amine stimulus GO:0014075 13 9 0,000 0,046856 0,08698267 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,046856 0,08691663 ! erythrocyte development GO:0048821 17 9 0,000 0,046856 0,08685068 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,046856 0,08678484 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,046856 0,08671909 ! postreplication repair GO:0006301 25 9 0,000 0,046856 0,08665344 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,046856 0,0865879 ! icosanoid secretion GO:0032309 15 9 0,000 0,046856 0,08652245 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,046856 0,0864571 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,046856 0,08639185 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,046856 0,08632669 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,046856 0,08626164 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,046856 0,08619668 ! sterol catabolic process GO:0016127 14 9 0,000 0,046856 0,08613183 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,046856 0,08606707 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,046856 0,0860024 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,046856 0,08593784 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,046856 0,08587337 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,046856 0,08580899 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,046856 0,08574472 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,046856 0,08568054 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,046856 0,08561645 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,046856 0,08555246 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,046856 0,08548857 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,046856 0,08542477 ! purine base metabolic process GO:0006144 25 9 0,000 0,046856 0,08536107 ! pigment granule transport GO:0051904 17 9 0,000 0,046856 0,08529746 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,046856 0,08523395 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,046856 0,08517053 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,046856 0,08510721 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,046856 0,08504398 ! mitochondrion localization GO:0051646 18 9 0,000 0,046856 0,08498084 ! lymphocyte mediated immunity GO:0002449 122 65 1,000 0,04702146 0,08521767 ! nucleoside monophosphate metabolic process GO:0009123 117 65 1,000 0,04702146 0,0851545 ! secondary metabolic process GO:0019748 125 67 1,000 0,04964241 0,08983438 ! regulation of cellular response to stress GO:0080135 142 68 1,000 0,05097234 0,09217278 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,05097234 0,0921046 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 1,000 0,05097234 0,09203653 ! viral reproduction GO:0016032 142 68 1,000 0,05097234 0,09196856 ! adaptive immune response GO:0002250 126 68 1,000 0,05097234 0,09190068 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell projection assembly GO:0030031 138 68 1,000 0,05097234 0,09183291 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,05192548 0,09348117 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05192548 0,09341234 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,05192548 0,0933436 ! associative learning GO:0008306 21 10 0,000 0,05192548 0,09327497 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05192548 0,09320643 ! phosphate transport GO:0006817 24 10 0,000 0,05192548 0,093138 ! cell volume homeostasis GO:0006884 17 10 0,000 0,05192548 0,09306967 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,05192548 0,09300143 ! CTP metabolic process GO:0046036 11 10 0,000 0,05192548 0,0929333 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,05192548 0,09286527 ! GTP metabolic process GO:0046039 11 10 0,000 0,05192548 0,09279733 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,05192548 0,0927295 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,05192548 0,09266176 ! social behavior GO:0035176 29 10 0,000 0,05192548 0,09259413 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,05192548 0,09252659 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,05192548 0,09245915 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,05192548 0,09239181 ! androgen metabolic process GO:0008209 17 10 0,000 0,05192548 0,09232457 ! phospholipid efflux GO:0033700 19 10 0,000 0,05192548 0,09225742 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05192548 0,09219037 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,05192548 0,09212342 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,05192548 0,09205657 ! lung alveolus development GO:0048286 26 10 0,000 0,05192548 0,09198981 ! pathogenesis GO:0009405 17 10 0,000 0,05192548 0,09192316 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05192548 0,09185659 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,05192548 0,09179013 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,05192548 0,09172376 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,05192548 0,09165748 ! endoderm development GO:0007492 18 10 0,000 0,05192548 0,0915913 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,05192548 0,09152522 ! arginine catabolic process GO:0006527 17 10 0,000 0,05192548 0,09145923 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05192548 0,09139334 ! proline metabolic process GO:0006560 13 10 0,000 0,05192548 0,09132754 ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,05192548 0,09126184 ! V(D)J recombination GO:0033151 34 10 0,000 0,05192548 0,09119623 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,05192548 0,09113071 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,05192548 0,09106529 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,05192548 0,09099997 ! B cell proliferation GO:0042100 19 10 0,000 0,05192548 0,09093473 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,05192548 0,09086959 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,05192548 0,09080455 ! multicellular organism growth GO:0035264 19 10 0,000 0,05192548 0,0907396 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,05192548 0,09067473 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,05192548 0,09060997 ! ruffle organization GO:0031529 17 10 0,000 0,05192548 0,09054529 ! epithelial cell development GO:0002064 21 10 0,000 0,05192548 0,09048071 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05192548 0,09041622 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,05192548 0,09035182 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,05192548 0,09028751 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,05192548 0,0902233 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,05192548 0,09015917 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,05192548 0,09009514 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05192548 0,0900312 ! brain morphogenesis GO:0048854 23 10 0,000 0,05192548 0,08996734 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,05192548 0,08990358 ! segment specification GO:0007379 15 10 0,000 0,05192548 0,08983991 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,05192548 0,08977633 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,05192548 0,08971284 ! blastoderm segmentation GO:0007350 19 10 0,000 0,05192548 0,08964944 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,05192548 0,08958613 ! response to dsRNA GO:0043331 23 10 0,000 0,05192548 0,0895229 ! DNA ligation GO:0006266 18 10 0,000 0,05192548 0,08945977 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,05192548 0,08939673 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05192548 0,08933377 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,05192548 0,0892709 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,05192548 0,08920813 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,05192548 0,08914543 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05192548 0,08908283 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,05192548 0,08902032 ! induction of an organ GO:0001759 17 10 0,000 0,05192548 0,08895789 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,05192548 0,08889555 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,05192548 0,0888333 ! protein sumoylation GO:0016925 17 10 0,000 0,05192548 0,08877114 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,05192548 0,08870906 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05192548 0,08864707 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05192548 0,08858516 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05192548 0,08852335 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,05192548 0,08846161 ! salivary gland development GO:0007431 28 10 0,000 0,05192548 0,08839997 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,05192548 0,08833841 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,05192548 0,08827693 ! midbrain development GO:0030901 14 10 0,000 0,05192548 0,08821555 ! musculoskeletal movement GO:0050881 16 10 0,000 0,05192548 0,08815424 GO:0050879|multicellular organismal movement, ! methionine biosynthetic process GO:0009086 21 10 0,000 0,05192548 0,08809302 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,05192548 0,08803189 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,05192548 0,08797084 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,05192548 0,08790988 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05192548 0,087849 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05192548 0,0877882 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,05192548 0,08772749 ! detection of calcium ion GO:0005513 24 10 0,000 0,05192548 0,08766687 ! blastocyst formation GO:0001825 18 10 0,000 0,05192548 0,08760632 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,05192548 0,08754586 ! cerebellar cortex development GO:0021695 16 10 0,000 0,05192548 0,08748549 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,05192548 0,08742519 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,05192548 0,08736498 ! response to nicotine GO:0035094 20 10 0,000 0,05192548 0,08730485 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,05192548 0,08724481 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05192548 0,08718485 ! actin filament organization GO:0007015 167 72 1,000 0,05641769 0,09466237 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,05641769 0,0945974 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,05696815 0,09545486 ! respiratory burst GO:0045730 17 11 0,000 0,05696815 0,09538944 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,05696815 0,0953241 ! neuron fate specification GO:0048665 18 11 0,000 0,05696815 0,09525885 ! telencephalon cell migration GO:0022029 23 11 0,000 0,05696815 0,0951937 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,05696815 0,09512863 ! thyroid gland development GO:0030878 26 11 0,000 0,05696815 0,09506365 ! synapsis GO:0007129 14 11 0,000 0,05696815 0,09499876 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,05696815 0,09493396 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,05696815 0,09486925 ! response to pain GO:0048265 27 11 0,000 0,05696815 0,09480462 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,05696815 0,09474009 ! blood vessel remodeling GO:0001974 30 11 0,000 0,05696815 0,09467564 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,05696815 0,09461128 ! bone resorption GO:0045453 16 11 0,000 0,05696815 0,094547 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,05696815 0,09448281 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05696815 0,09441872 ! melanocyte differentiation GO:0030318 20 11 0,000 0,05696815 0,0943547 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,05696815 0,09429078 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,05696815 0,09422694 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,05696815 0,09416318 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,05696815 0,09409952 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,05696815 0,09403594 ! UV protection GO:0009650 20 11 0,000 0,05696815 0,09397244 ! adult heart development GO:0007512 16 11 0,000 0,05696815 0,09390903 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,05696815 0,09384571 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05696815 0,09378247 ! macroautophagy GO:0016236 19 11 0,000 0,05696815 0,09371932 ! temperature homeostasis GO:0001659 18 11 0,000 0,05696815 0,09365625 ! behavioral fear response GO:0001662 27 11 0,000 0,05696815 0,09359327 GO:0002209|behavioral defense response, ! negative regulation of ossification GO:0030279 27 11 0,000 0,05696815 0,09353037 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,05696815 0,09346755 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,05696815 0,09340482 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,05696815 0,09334218 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,05696815 0,09327962 ! regulation of organ growth GO:0046620 14 11 0,000 0,05696815 0,09321714 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,05696815 0,09315474 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,05696815 0,09309243 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05696815 0,0930302 ! embryonic axis specification GO:0000578 19 11 0,000 0,05696815 0,09296806 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,05696815 0,092906 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05696815 0,09284402 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,05696815 0,09278212 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,05696815 0,09272031 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,05696815 0,09265858 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,05696815 0,09259693 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,05696815 0,09253536 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,05696815 0,09247388 ! prophase GO:0051324 17 11 0,000 0,05696815 0,09241247 ! nucleosome positioning GO:0016584 15 11 0,000 0,05696815 0,09235115 ! regulation of isotype switching GO:0045191 24 11 0,000 0,05696815 0,09228991 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,05696815 0,09222875 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,05696815 0,09216767 ! acid secretion GO:0046717 20 11 0,000 0,05696815 0,09210668 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05696815 0,09204576 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,05696815 0,09198492 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,05696815 0,09192417 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,05696815 0,09186349 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,05696815 0,09180289 ! thymus development GO:0048538 29 11 0,000 0,05696815 0,09174238 ! cholesterol efflux GO:0033344 21 11 0,000 0,05696815 0,09168194 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05696815 0,09162158 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,05696815 0,09156131 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,05696815 0,09150111 ! embryonic gut development GO:0048566 19 11 0,000 0,05696815 0,09144099 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,05696815 0,09138095 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,05696815 0,09132099 ! activation of innate immune response GO:0002218 16 11 0,000 0,05696815 0,09126111 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,05696815 0,0912013 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,05696815 0,09114158 ! lysogeny GO:0030069 22 11 0,000 0,05696815 0,09108193 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05696815 0,09102236 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,05696815 0,09096287 ! sequestering of metal ion GO:0051238 15 11 0,000 0,05696815 0,09090345 ! nucleus localization GO:0051647 22 11 0,000 0,05696815 0,09084412 ! humoral immune response GO:0006959 115 73 1,000 0,05780959 0,09212579 ! regulation of immune effector process GO:0002697 156 73 1,000 0,05780959 0,09206573 ! organelle localization GO:0051640 155 74 1,000 0,05921338 0,09423993 ! transition metal ion transport GO:0000041 143 75 1,000 0,06062891 0,09642996 ! leukocyte mediated immunity GO:0002443 136 75 1,000 0,06062891 0,09636722 ! axon guidance GO:0007411 162 75 1,000 0,06062891 0,09630456 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,06198413 0,09839327 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,06198413 0,09832938 ! regulation of positive chemotaxis GO:0050926 22 12 0,000 0,06198413 0,09826557 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,06198413 0,09820184 ! protein complex disassembly GO:0043241 28 12 0,000 0,06198413 0,0981382 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06198413 0,09807464 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,06198413 0,09801116 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,06198413 0,09794776 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,06198413 0,09788445 ! T cell proliferation GO:0042098 32 12 0,000 0,06198413 0,09782121 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06198413 0,09775806 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,06198413 0,09769499 ! ventral spinal cord development GO:0021517 25 12 0,000 0,06198413 0,097632 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,06198413 0,0975691 ! drug transport GO:0015893 16 12 0,000 0,06198413 0,09750627 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,06198413 0,09744353 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,06198413 0,09738086 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,06198413 0,09731828 ! polyamine metabolic process GO:0006595 18 12 0,000 0,06198413 0,09725577 ! focal adhesion formation GO:0048041 37 12 0,000 0,06198413 0,09719335 ! mitotic spindle organization GO:0007052 23 12 0,000 0,06198413 0,09713101 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,06198413 0,09706874 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,06198413 0,09700656 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,06198413 0,09694446 ! lipid digestion GO:0044241 21 12 0,000 0,06198413 0,09688243 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,06198413 0,09682049 ! entry into host cell GO:0030260 34 12 0,000 0,06198413 0,09675862 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06198413 0,09669683 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,06198413 0,09663512 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,06198413 0,09657349 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06198413 0,09651194 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,06198413 0,09645047 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,06198413 0,09638908 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,06198413 0,09632776 ! snRNA metabolic process GO:0016073 30 12 0,000 0,06198413 0,09626652 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,06198413 0,09620536 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,06198413 0,09614428 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06198413 0,09608327 ! cranial nerve development GO:0021545 23 12 0,000 0,06198413 0,09602235 ! fucose catabolic process GO:0019317 25 12 0,000 0,06198413 0,0959615 GO:0042355|L-fucose catabolic process, ! mRNA polyadenylation GO:0006378 24 12 0,000 0,06198413 0,09590072 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06198413 0,09584002 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,06198413 0,09577941 ! zymogen activation GO:0031638 18 12 0,000 0,06198413 0,09571886 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,06198413 0,0956584 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,06198413 0,095598 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,06198413 0,09553769 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,06198413 0,09547745 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,06198413 0,09541729 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,06198413 0,0953572 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,06198413 0,09529719 ! defense response to fungus GO:0050832 15 12 0,000 0,06198413 0,09523726 ! developmental induction GO:0031128 22 12 0,000 0,06198413 0,0951774 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,06198413 0,09511761 ! lamellipodium assembly GO:0030032 24 12 0,000 0,06198413 0,0950579 ! response to cold GO:0009409 17 12 0,000 0,06198413 0,09499827 ! establishment of cell polarity GO:0030010 21 12 0,000 0,06198413 0,09493871 ! regulation of synapse organization GO:0050807 18 12 0,000 0,06198413 0,09487922 ! learning or memory GO:0007611 161 76 1,000 0,06205599 0,09492974 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 1,000 0,06205599 0,09487033 ! regulation of blood pressure GO:0008217 134 76 1,000 0,06205599 0,094811 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,06205599 0,09475174 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,06349448 0,09688758 ! cytosolic calcium ion homeostasis GO:0051480 149 77 1,000 0,06349448 0,0968271 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,06494421 0,09897612 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 0,06640503 0,10113933 ! steroid biosynthetic process GO:0006694 146 79 1,000 0,06640503 0,10107632 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,06697358 0,10187824 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06697358 0,10181485 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,06697358 0,10175153 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06697358 0,10168829 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06697358 0,10162513 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,06697358 0,10156205 ! peroxisomal transport GO:0043574 28 13 0,000 0,06697358 0,10149904 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,06697358 0,10143612 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,06697358 0,10137327 ! organelle fusion GO:0048284 36 13 0,000 0,06697358 0,1013105 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,06697358 0,10124781 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,06697358 0,10118519 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,06697358 0,10112266 ! endocrine pancreas development GO:0031018 25 13 0,000 0,06697358 0,1010602 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,06697358 0,10099781 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,06697358 0,10093551 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,06697358 0,10087328 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,06697358 0,10081113 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,06697358 0,10074905 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06697358 0,10068705 ! methionine metabolic process GO:0006555 31 13 0,000 0,06697358 0,10062513 ! plasma membrane organization GO:0007009 27 13 0,000 0,06697358 0,10056328 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,06697358 0,10050151 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,06697358 0,10043981 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,06697358 0,10037819 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,06697358 0,10031665 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,06697358 0,10025518 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,06697358 0,10019379 ! exocrine system development GO:0035272 34 13 0,000 0,06697358 0,10013247 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,06697358 0,10007123 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,06697358 0,10001006 ! L-glutamate transport GO:0015813 30 13 0,000 0,06697358 0,09994897 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,06697358 0,09988795 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,06697358 0,099827 ! protein homotetramerization GO:0051289 24 13 0,000 0,06697358 0,09976613 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,06697358 0,09970534 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,06697358 0,09964461 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,06697358 0,09958397 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,06697358 0,09952339 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,06697358 0,09946289 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06697358 0,09940246 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,06697358 0,09934211 ! histone methylation GO:0016571 29 13 0,000 0,06697358 0,09928183 ! chromatin silencing GO:0006342 29 13 0,000 0,06697358 0,09922162 ! gland morphogenesis GO:0022612 31 13 0,000 0,06697358 0,09916149 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,06697358 0,09910143 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,06697358 0,09904144 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06697358 0,09898152 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,06697358 0,09892168 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,06697358 0,09886191 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,06697358 0,09880221 ! spleen development GO:0048536 24 13 0,000 0,06697358 0,09874258 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,06697358 0,09868303 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,06697358 0,09862354 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,06697358 0,09856413 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,06697358 0,09850479 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,06697358 0,09844552 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06697358 0,09838632 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,06697358 0,0983272 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,06697358 0,09826814 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,06697358 0,09820916 ! insulin secretion GO:0030073 24 13 0,000 0,06697358 0,09815024 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,06697358 0,0980914 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,06697358 0,09803263 ! acrosome reaction GO:0007340 19 13 0,000 0,06697358 0,09797393 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,06697358 0,09791529 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,06697358 0,09785673 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,06787678 0,09911713 ! rRNA transcription GO:0009303 28 14 0,000 0,07193663 0,10498278 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,07193663 0,10492011 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,07193663 0,1048575 ! water transport GO:0006833 21 14 0,000 0,07193663 0,10479498 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,07193663 0,10473253 ! non-recombinational repair GO:0000726 29 14 0,000 0,07193663 0,10467015 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,07193663 0,10460784 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,07193663 0,10454561 ! RNA polyadenylation GO:0043631 32 14 0,000 0,07193663 0,10448346 ! lipid localization GO:0010876 32 14 0,000 0,07193663 0,10442138 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,07193663 0,10435937 ! regulated secretory pathway GO:0045055 24 14 0,000 0,07193663 0,10429743 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,07193663 0,10423557 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,07193663 0,10417379 ! arginine metabolic process GO:0006525 21 14 0,000 0,07193663 0,10411207 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,07193663 0,10405043 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,07193663 0,10398886 ! fear response GO:0042596 34 14 0,000 0,07193663 0,10392737 ! organic alcohol transport GO:0015850 29 14 0,000 0,07193663 0,10386594 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,07193663 0,10380459 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,07193663 0,10374332 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,07193663 0,10368211 ! neutral amino acid transport GO:0015804 28 14 0,000 0,07193663 0,10362098 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,07193663 0,10355992 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,07193663 0,10349893 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,07193663 0,10343801 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,07193663 0,10337716 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,07193663 0,10331639 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,07193663 0,10325569 ! ribosome assembly GO:0042255 18 14 0,000 0,07193663 0,10319505 ! cerebellum development GO:0021549 23 14 0,000 0,07193663 0,10313449 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,07193663 0,103074 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,07193663 0,10301359 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,07193663 0,10295324 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,07193663 0,10289296 ! NADP metabolic process GO:0006739 24 14 0,000 0,07193663 0,10283275 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,07193663 0,10277262 ! oxygen transport GO:0015671 22 14 0,000 0,07193663 0,10271255 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07193663 0,10265256 ! male genitalia development GO:0030539 26 14 0,000 0,07193663 0,10259263 ! regulation of RNA stability GO:0043487 33 14 0,000 0,07193663 0,10253278 ! regulation of axon extension GO:0030516 43 14 0,000 0,07193663 0,10247299 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,07193663 0,10241327 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,07193663 0,10235363 ! response to metal ion GO:0010038 158 84 1,000 0,07386992 0,1050432 ! T cell activation GO:0042110 189 84 1,000 0,07386992 0,10498209 ! response to nutrient GO:0007584 135 84 1,000 0,07386992 0,10492106 ! digestion GO:0007586 130 84 1,000 0,07386992 0,10486009 ! regulation of ligase activity GO:0051340 147 84 1,000 0,07386992 0,1047992 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07687341 0,10899695 ! lactation GO:0007595 30 15 0,000 0,07687341 0,10893373 ! reproductive cellular process GO:0048610 22 15 0,000 0,07687341 0,10887058 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07687341 0,1088075 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,07687341 0,1087445 ! superoxide anion generation GO:0042554 22 15 0,000 0,07687341 0,10868156 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,07687341 0,10861871 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,07687341 0,10855592 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,07687341 0,10849321 ! copper ion transport GO:0006825 22 15 0,000 0,07687341 0,10843057 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,07687341 0,108368 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,07687341 0,1083055 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,07687341 0,10824308 ! sulfate transport GO:0008272 27 15 0,000 0,07687341 0,10818073 ! response to cAMP GO:0051591 25 15 0,000 0,07687341 0,10811845 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,07687341 0,10805624 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,07687341 0,1079941 ! response to hexose stimulus GO:0009746 25 15 0,000 0,07687341 0,10793204 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,07687341 0,10787004 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,07687341 0,10780812 ! vesicle coating GO:0006901 38 15 0,000 0,07687341 0,10774627 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,07687341 0,10768449 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,07687341 0,10762278 ! regulation of exocytosis GO:0017157 26 15 0,000 0,07687341 0,10756114 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,07687341 0,10749957 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,07687341 0,10743807 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,07687341 0,10737664 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,07687341 0,10731528 ! regulation of vasodilation GO:0042312 27 15 0,000 0,07687341 0,10725399 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,07687341 0,10719278 ! histone deacetylation GO:0016575 24 15 0,000 0,07687341 0,10713163 ! cofactor transport GO:0051181 30 15 0,000 0,07687341 0,10707055 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07687341 0,10700954 ! muscle maintenance GO:0046716 26 15 0,000 0,07687341 0,1069486 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,07687341 0,10688773 ! intestinal absorption GO:0050892 31 15 0,000 0,07687341 0,10682693 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07687341 0,1067662 ! heme biosynthetic process GO:0006783 33 15 0,000 0,07687341 0,10670554 ! cell killing GO:0001906 32 15 0,000 0,07687341 0,10664494 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,07687341 0,10658442 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,07687341 0,10652396 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,07687341 0,10646357 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,07687341 0,10640325 ! actin filament polymerization GO:0030041 27 15 0,000 0,07687341 0,106343 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,07687341 0,10628282 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,07692806 0,10629822 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,07692806 0,10623813 GO:0002696|positive regulation of leukocyte activation, ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,08158888 0,11261109 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,08178407 0,11281677 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,08178407 0,1127531 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,08178407 0,11268951 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,08178407 0,11262598 ! bone remodeling GO:0046849 28 16 0,000 0,08178407 0,11256253 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,08178407 0,11249915 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08178407 0,11243584 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,08178407 0,11237261 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,08178407 0,11230944 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,08178407 0,11224634 ! startle response GO:0001964 28 16 0,000 0,08178407 0,11218332 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,08178407 0,11212037 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,08178407 0,11205748 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,08178407 0,11199467 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,08178407 0,11193193 ! protein polyubiquitination GO:0000209 41 16 0,000 0,08178407 0,11186926 ! glutamate metabolic process GO:0006536 25 16 0,000 0,08178407 0,11180665 ! pituitary gland development GO:0021983 30 16 0,000 0,08178407 0,11174412 ! lysosomal transport GO:0007041 31 16 0,000 0,08178407 0,11168166 ! fructose metabolic process GO:0006000 25 16 0,000 0,08178407 0,11161927 ! L-amino acid transport GO:0015807 33 16 0,000 0,08178407 0,11155695 ! stem cell development GO:0048864 46 16 0,000 0,08178407 0,11149469 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08178407 0,11143251 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08178407 0,1113704 ! intermediate filament-based process GO:0045103 36 16 0,000 0,08178407 0,11130835 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,08178407 0,11124638 ! negative regulation of immune response GO:0050777 38 16 0,000 0,08178407 0,11118447 ! axon cargo transport GO:0008088 46 16 0,000 0,08178407 0,11112263 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,08178407 0,11106086 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,08178407 0,11099916 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,08178407 0,11093753 ! neuron recognition GO:0008038 40 16 0,000 0,08178407 0,11087597 ! mRNA splice site selection GO:0006376 44 16 0,000 0,08178407 0,11081447 ! tissue regeneration GO:0042246 27 16 0,000 0,08178407 0,11075304 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,08178407 0,11069169 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,08178407 0,11063039 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,08178407 0,11056917 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,08178407 0,11050802 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,08178407 0,11044693 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08178407 0,11038591 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,08178407 0,11032495 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,08178407 0,11026407 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,08178407 0,11020325 ! peptide hormone processing GO:0016486 27 16 0,000 0,08178407 0,1101425 ! response to inorganic substance GO:0010035 173 90 1,000 0,08316153 0,11193587 ! response to unfolded protein GO:0006986 139 90 1,000 0,08316153 0,11187423 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,08474346 0,11393961 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 1,000 0,08474346 0,11387693 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,08666875 0,11640009 ! metencephalon development GO:0022037 32 17 0,000 0,08666875 0,11633613 ! negative regulation of cell cycle process GO:0010948 35 17 0,000 0,08666875 0,11627225 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,08666875 0,11620843 ! signal complex assembly GO:0007172 47 17 0,000 0,08666875 0,11614468 ! filopodium assembly GO:0046847 42 17 0,000 0,08666875 0,11608101 ! endothelial cell migration GO:0043542 31 17 0,000 0,08666875 0,1160174 ! gene silencing by RNA GO:0031047 38 17 0,000 0,08666875 0,11595387 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,08666875 0,1158904 ! glial cell development GO:0021782 28 17 0,000 0,08666875 0,115827 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,08666875 0,11576367 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,08666875 0,11570041 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,08666875 0,11563722 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,08666875 0,1155741 ! myoblast differentiation GO:0045445 50 17 0,000 0,08666875 0,11551105 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,08666875 0,11544807 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,08666875 0,11538515 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,08666875 0,11532231 ! NAD metabolic process GO:0019674 33 17 0,000 0,08666875 0,11525953 ! membrane budding GO:0006900 42 17 0,000 0,08666875 0,11519682 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,08666875 0,11513418 ! regulation of protein binding GO:0043393 33 17 0,000 0,08666875 0,11507161 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,08666875 0,1150091 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,08666875 0,11494667 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,08666875 0,1148843 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,08666875 0,11482199 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,08666875 0,11475976 ! steroid catabolic process GO:0006706 34 17 0,000 0,08666875 0,11469759 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,08666875 0,11463549 ! gas transport GO:0015669 26 17 0,000 0,08666875 0,11457346 ! organic cation transport GO:0015695 32 17 0,000 0,08666875 0,1145115 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,08666875 0,1144496 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,08666875 0,11438777 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,08666875 0,114326 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,0879346 0,1159332 ! vitamin metabolic process GO:0006766 153 93 1,000 0,0879346 0,11587067 ! female pregnancy GO:0007565 166 94 1,000 0,08954353 0,11792714 ! phospholipid biosynthetic process GO:0008654 188 95 1,000 0,09116118 0,11999287 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,09116118 0,11992825 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,09152758 0,12034547 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,09152758 0,12028073 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,09152758 0,12021606 ! negative regulation of ion transport GO:0043271 25 18 0,000 0,09152758 0,12015147 ! adult walking behavior GO:0007628 36 18 0,000 0,09152758 0,12008694 ! heart looping GO:0001947 34 18 0,000 0,09152758 0,12002248 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,09152758 0,11995809 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,09152758 0,11989377 ! centrosome cycle GO:0007098 26 18 0,000 0,09152758 0,11982952 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,09152758 0,11976533 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,09152758 0,11970122 ! glycine metabolic process GO:0006544 30 18 0,000 0,09152758 0,11963717 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09152758 0,1195732 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,09152758 0,11950929 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,09152758 0,11944545 ! DNA integration GO:0015074 32 18 0,000 0,09152758 0,11938167 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,09152758 0,11931797 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,09152758 0,11925433 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,09152758 0,11919077 ! neural crest cell migration GO:0001755 41 18 0,000 0,09152758 0,11912727 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,09152758 0,11906383 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,09152758 0,11900047 GO:0046466|membrane lipid catabolic process, ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,09152758 0,11893717 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,09152758 0,11887394 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,09152758 0,11881077 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,09152758 0,11874768 ! detection of bacterium GO:0016045 22 18 0,000 0,09152758 0,11868465 ! nerve development GO:0021675 34 18 0,000 0,09152758 0,11862169 ! defense response to virus GO:0051607 43 18 0,000 0,09152758 0,11855879 ! microspike assembly GO:0030035 46 18 0,000 0,09152758 0,11849596 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,09152758 0,1184332 ! response to protein stimulus GO:0051789 158 96 1,000 0,09278742 0,11999982 ! leukocyte differentiation GO:0002521 232 98 1,000 0,0960651 0,12417304 ! forebrain development GO:0030900 210 98 1,000 0,0960651 0,12410738 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,0960651 0,12404178 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,0963607 0,12435773 ! positive regulation of translation GO:0045727 31 19 0,000 0,0963607 0,12429207 ! negative regulation of defense response GO:0031348 27 19 0,000 0,0963607 0,12422648 ! neuron maturation GO:0042551 46 19 0,000 0,0963607 0,12416096 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,0963607 0,12409551 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,0963607 0,12403013 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,0963607 0,12396481 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,0963607 0,12389957 ! inositol metabolic process GO:0006020 33 19 0,000 0,0963607 0,12383439 ! memory GO:0007613 34 19 0,000 0,0963607 0,12376929 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,0963607 0,12370425 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,0963607 0,12363928 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,0963607 0,12357437 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,0963607 0,12350954 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,0963607 0,12344477 ! cerebral cortex development GO:0021987 40 19 0,000 0,0963607 0,12338007 ! pigmentation during development GO:0048066 42 19 0,000 0,0963607 0,12331544 ! heme metabolic process GO:0042168 40 19 0,000 0,0963607 0,12325088 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,0963607 0,12318638 ! response to fungus GO:0009620 26 19 0,000 0,0963607 0,12312196 ! protein export from nucleus GO:0006611 40 19 0,000 0,0963607 0,1230576 ! heart process GO:0003015 32 19 0,000 0,0963607 0,1229933 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,0963607 0,12292908 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,0963607 0,12286492 ! visual learning GO:0008542 38 19 0,000 0,0963607 0,12280082 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,0963607 0,1227368 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,0963607 0,12267284 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,0963607 0,12260895 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,0963607 0,12254512 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,0963607 0,12248136 ! cilium assembly GO:0042384 38 19 0,000 0,0963607 0,12241767 ! protein secretion GO:0009306 45 20 0,000 0,10116824 0,12845842 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,10116824 0,12839169 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,10116824 0,12832503 ! positive regulation of ossification GO:0045778 50 20 0,000 0,10116824 0,12825843 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,10116824 0,12819191 ! skin development GO:0043588 42 20 0,000 0,10116824 0,12812545 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,10116824 0,12805907 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,10116824 0,12799275 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,10116824 0,1279265 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,10116824 0,12786032 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,10116824 0,12779421 ! bile acid metabolic process GO:0008206 34 20 0,000 0,10116824 0,12772816 ! pancreas development GO:0031016 40 20 0,000 0,10116824 0,12766219 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,10116824 0,12759628 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,10116824 0,12753044 GO:0032392|DNA geometric change, ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,10116824 0,12746467 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,10116824 0,12739897 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,10116824 0,12733333 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,10116824 0,12726776 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,10116824 0,12720226 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,10116824 0,12713683 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,10116824 0,12707146 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,10116824 0,12700617 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,10116824 0,12694093 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,10116824 0,12687577 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,10116824 0,12681067 ! regulation of glucose import GO:0046324 30 20 0,000 0,10116824 0,12674564 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,10116824 0,12668068 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,10116824 0,12661578 ! regulation of cell killing GO:0031341 46 21 0,000 0,10595033 0,13253285 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,10595033 0,13246503 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,10595033 0,13239727 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,10595033 0,13232958 ! ovarian follicle development GO:0001541 39 21 0,000 0,10595033 0,13226196 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,10595033 0,13219441 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,10595033 0,13212693 ! plasma membrane fusion GO:0045026 33 21 0,000 0,10595033 0,13205952 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,10595033 0,13199218 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,10595033 0,1319249 GO:0006692|prostanoid metabolic process, ! sensory perception of pain GO:0019233 33 21 0,000 0,10595033 0,1318577 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,10595033 0,13179056 ! diencephalon development GO:0021536 36 21 0,000 0,10595033 0,13172349 ! collagen fibril organization GO:0030199 62 21 0,000 0,10595033 0,13165649 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,10595033 0,13158956 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,10595033 0,13152269 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,10595033 0,1314559 ! collagen catabolic process GO:0030574 29 21 0,000 0,10595033 0,13138917 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,10595033 0,13132251 GO:0043450|alkene biosynthetic process, ! sperm-egg recognition GO:0035036 23 21 0,000 0,10595033 0,13125591 ! actin filament-based movement GO:0030048 47 21 0,000 0,10595033 0,13118939 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,11070712 0,13700988 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,11070712 0,1369405 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,11070712 0,1368712 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,11070712 0,13680197 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,11070712 0,13673281 ! microtubule-based transport GO:0010970 59 22 0,000 0,11070712 0,13666372 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,11070712 0,13659469 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,11070712 0,13652574 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,11070712 0,13645686 ! vacuolar transport GO:0007034 41 22 0,000 0,11070712 0,13638805 ! central nervous system neuron development GO:0021954 47 22 0,000 0,11070712 0,1363193 ! fucose metabolic process GO:0006004 44 22 0,000 0,11070712 0,13625063 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,11070712 0,13618202 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,11070712 0,13611348 ! ureteric bud development GO:0001657 50 22 0,000 0,11070712 0,13604502 ! stem cell differentiation GO:0048863 57 22 0,000 0,11070712 0,13597662 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,11070712 0,13590829 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,11070712 0,13584003 ! vasodilation GO:0042311 40 22 0,000 0,11070712 0,13577183 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,11070712 0,13570371 ! positive regulation of locomotion GO:0040017 44 22 0,000 0,11070712 0,13563565 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of chemical stimulus GO:0009593 42 22 0,000 0,11070712 0,13556767 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,11070712 0,13549975 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,11070712 0,13543189 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,11070712 0,13536411 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,11070712 0,1352964 ! sarcomere organization GO:0045214 32 22 0,000 0,11070712 0,13522875 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,11070712 0,13516117 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,11070712 0,13509365 ! gut development GO:0048565 44 22 0,000 0,11070712 0,13502621 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,11070712 0,13495883 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 0,000 0,11070712 0,13489152 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,11070712 0,13482427 ! protein stabilization GO:0050821 41 22 0,000 0,11070712 0,1347571 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,11543873 0,14044663 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,11543873 0,14037672 ! glycerol metabolic process GO:0006071 40 23 0,000 0,11543873 0,14030688 ! viral genome replication GO:0019079 44 23 0,000 0,11543873 0,14023711 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,11543873 0,14016741 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,11543873 0,14009778 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of chemotaxis GO:0050920 45 23 0,000 0,11543873 0,14002821 ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,11543873 0,13995872 ! regeneration GO:0031099 42 23 0,000 0,11543873 0,1398893 ! axis specification GO:0009798 43 23 0,000 0,11543873 0,13981994 ! visual behavior GO:0007632 46 23 0,000 0,11543873 0,13975066 ! response to ethanol GO:0045471 47 23 0,000 0,11543873 0,13968144 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,11543873 0,13961229 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,11543873 0,13954321 ! peroxisome organization GO:0007031 43 23 0,000 0,11543873 0,1394742 ! lysosome organization GO:0007040 47 23 0,000 0,11543873 0,13940525 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,11543873 0,13933638 ! vesicle targeting GO:0006903 49 23 0,000 0,11543873 0,13926757 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,11543873 0,13919883 GO:0060415|muscle tissue morphogenesis, ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,11543873 0,13913016 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,11543873 0,13906155 ! DNA modification GO:0006304 36 23 0,000 0,11543873 0,13899301 ! fatty acid transport GO:0015908 47 23 0,000 0,11543873 0,13892454 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,11543873 0,13885614 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,11543873 0,13878781 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,11543873 0,13871954 ! cell-cell recognition GO:0009988 28 23 0,000 0,11543873 0,13865134 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,11543873 0,13858321 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,11543873 0,13851514 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,11543873 0,13844714 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,1201453 0,14402109 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,1201453 0,14395045 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,1201453 0,14387989 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,1201453 0,1438094 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,1201453 0,14373897 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,1201453 0,14366861 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,1201453 0,14359832 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,1201453 0,14352811 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,1201453 0,14345795 GO:0042278|purine nucleoside metabolic process, ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,1201453 0,14338787 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,1201453 0,14331786 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,1201453 0,14324791 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,1201453 0,14317804 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,1201453 0,14310823 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,1201453 0,14303849 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,1201453 0,14296881 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,1201453 0,14289921 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,1201453 0,14282967 ! platelet activation GO:0030168 41 24 0,000 0,1201453 0,1427602 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,1201453 0,1426908 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,1201453 0,14262147 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,1201453 0,1425522 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,1201453 0,142483 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,1201453 0,14241386 ! regulation of amine transport GO:0051952 41 24 0,000 0,1201453 0,1423448 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,12482696 0,14781981 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,12482696 0,14774819 ! leukocyte adhesion GO:0007159 55 25 0,000 0,12482696 0,14767664 ! phototransduction GO:0007602 37 25 0,000 0,12482696 0,14760516 ! vasculogenesis GO:0001570 49 25 0,000 0,12482696 0,14753375 ! vacuole organization GO:0007033 49 25 0,000 0,12482696 0,14746241 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,12482696 0,14739114 ! receptor metabolic process GO:0043112 53 25 0,000 0,12482696 0,14731994 ! chromosome condensation GO:0030261 48 25 0,000 0,12482696 0,1472488 ! regulation of behavior GO:0050795 48 25 0,000 0,12482696 0,14717774 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,12482696 0,14710674 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,12482696 0,14703581 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,12482696 0,14696495 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,12482696 0,14689416 ! liver development GO:0001889 55 25 0,000 0,12482696 0,14682343 ! initiation of viral infection GO:0019059 60 26 0,000 0,12948384 0,15222764 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,12948384 0,15215441 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,12948384 0,15208126 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,12948384 0,15200818 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,12948384 0,15193517 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,12948384 0,15186223 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,12948384 0,15178936 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,12948384 0,15171656 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,12948384 0,15164383 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,12948384 0,15157117 ! osteoblast differentiation GO:0001649 63 26 0,000 0,12948384 0,15149858 ! coenzyme catabolic process GO:0009109 42 26 0,000 0,12948384 0,15142605 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,12948384 0,1513536 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,12948384 0,15128122 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,12948384 0,1512089 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,12948384 0,15113666 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,12948384 0,15106448 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,12948384 0,15099238 ! blastocyst development GO:0001824 50 26 0,000 0,12948384 0,15092034 ! telomere organization GO:0032200 46 26 0,000 0,12948384 0,15084837 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,12948384 0,15077647 ! neural tube closure GO:0001843 58 26 0,000 0,12948384 0,15070463 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,12948384 0,15063287 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,12948384 0,15056117 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,13411607 0,15587325 ! embryonic pattern specification GO:0009880 49 27 0,000 0,13411607 0,15579913 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,13411607 0,15572508 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,13411607 0,1556511 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,13411607 0,15557719 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,13411607 0,15550335 ! superoxide metabolic process GO:0006801 41 27 0,000 0,13411607 0,15542958 ! tube lumen formation GO:0035148 59 27 0,000 0,13411607 0,15535589 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,13411607 0,15528226 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,13411607 0,1552087 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,13411607 0,15513521 ! response to toxin GO:0009636 49 27 0,000 0,13411607 0,15506179 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,13411607 0,15498844 ! leukocyte proliferation GO:0070661 59 27 0,000 0,13411607 0,15491516 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,13872378 0,16016172 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,13872378 0,16008607 ! vesicle docking GO:0048278 55 28 0,000 0,13872378 0,16001048 ! circadian rhythm GO:0007623 56 28 0,000 0,13872378 0,15993497 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,13872378 0,15985953 ! sperm motility GO:0030317 37 28 0,000 0,13872378 0,15978416 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,13872378 0,15970886 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,13872378 0,15963363 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,13872378 0,15955848 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,13872378 0,15948339 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,13872378 0,15940837 ! glutathione metabolic process GO:0006749 42 28 0,000 0,13872378 0,15933343 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,13872378 0,15925855 ! lipid oxidation GO:0034440 48 28 0,000 0,13872378 0,15918375 GO:0019395|fatty acid oxidation, ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,13872378 0,15910901 ! translational initiation GO:0006413 66 29 0,000 0,1433071 0,16428872 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,1433071 0,16421166 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,1433071 0,16413467 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,1433071 0,16405776 ! primary neural tube formation GO:0014020 61 29 0,000 0,1433071 0,16398091 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,1433071 0,16390414 ! synaptogenesis GO:0007416 46 29 0,000 0,1433071 0,16382745 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,1433071 0,16375082 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,1433071 0,16367427 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,1433071 0,16359778 ! phenol metabolic process GO:0018958 56 30 0,000 0,14786616 0,16872351 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,14786616 0,16864474 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,14786616 0,16856604 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,14786616 0,16848742 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,14786616 0,16840887 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,14786616 0,1683304 ! acute-phase response GO:0006953 50 30 0,000 0,14786616 0,16825199 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,14786616 0,16817367 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,14786616 0,16809541 ! myofibril assembly GO:0030239 50 30 0,000 0,14786616 0,16801722 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,14786616 0,16793911 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,14786616 0,16786107 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,14786616 0,16778311 ! cell fate determination GO:0001709 64 30 0,000 0,14786616 0,16770521 ! phospholipid transport GO:0015914 65 30 0,000 0,14786616 0,16762739 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,14786616 0,16754964 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,14786616 0,16747197 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,14786616 0,16739436 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,15240109 0,17244829 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,15240109 0,17236845 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,15240109 0,17228869 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,15240109 0,172209 ! cell junction assembly GO:0034329 85 31 0,000 0,15240109 0,17212938 ! regulation of innate immune response GO:0045088 57 31 0,000 0,15240109 0,17204984 ! ovulation cycle process GO:0022602 55 31 0,000 0,15240109 0,17197037 ! male gonad development GO:0008584 56 31 0,000 0,15240109 0,17189098 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,15240109 0,17181165 ! detection of light stimulus GO:0009583 44 31 0,000 0,15240109 0,1717324 ! natural killer cell activation GO:0030101 50 31 0,000 0,15240109 0,17165323 ! cofactor catabolic process GO:0051187 54 31 0,000 0,15240109 0,17157413 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,15240109 0,1714951 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,15240109 0,17141614 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,156912 0,17640866 ! collagen metabolic process GO:0032963 49 32 0,000 0,156912 0,17632752 ! spindle organization GO:0007051 50 32 0,000 0,156912 0,17624645 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,156912 0,17616545 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,156912 0,17608453 ! metanephros development GO:0001656 81 32 0,000 0,156912 0,17600368 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,156912 0,17592291 ! muscle cell development GO:0055001 52 32 0,000 0,156912 0,17584221 ! mesoderm formation GO:0001707 73 32 0,000 0,156912 0,17576159 ! ovulation cycle GO:0042698 57 32 0,000 0,156912 0,17568104 ! BMP signaling pathway GO:0030509 71 32 0,000 0,156912 0,17560056 ! hindbrain development GO:0030902 65 32 0,000 0,156912 0,17552016 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,156912 0,17543983 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,156912 0,17535957 ! gene silencing GO:0016458 71 32 0,000 0,156912 0,17527939 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,16139904 0,18020926 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,16139904 0,18012693 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,16139904 0,18004468 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,16139904 0,17996251 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,16139904 0,17988041 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,16139904 0,17979838 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,16139904 0,17971643 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,16139904 0,17963456 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,16139904 0,17955276 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,16586232 0,18443407 ! glial cell differentiation GO:0010001 67 34 0,000 0,16586232 0,18435016 ! post-embryonic development GO:0009791 76 34 0,000 0,16586232 0,18426632 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,16586232 0,18418257 ! cholesterol transport GO:0030301 62 34 0,000 0,16586232 0,18409889 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,16586232 0,18401528 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,16586232 0,18393175 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,16586232 0,1838483 ! formation of primary germ layer GO:0001704 76 34 0,000 0,16586232 0,18376492 ! cell fate specification GO:0001708 56 34 0,000 0,16586232 0,18368162 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,16586232 0,18359839 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,16586232 0,18351524 ! adult locomotory behavior GO:0008344 62 34 0,000 0,16586232 0,18343216 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,17030197 0,18825689 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,17030197 0,18817174 ! membrane docking GO:0022406 69 35 0,000 0,17030197 0,18808667 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,17030197 0,18800168 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,17030197 0,18791676 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,17030197 0,18783193 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,17030197 0,18774716 ! ceramide metabolic process GO:0006672 72 35 0,000 0,17030197 0,18766248 ! sterol transport GO:0015918 63 35 0,000 0,17030197 0,18757787 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,17030197 0,18749334 ! mitotic sister chromatid segregation GO:0000070 63 36 0,000 0,17471812 0,19226863 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,17471812 0,19218206 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,17471812 0,19209557 ! positive regulation of cell development GO:0010720 85 36 0,000 0,17471812 0,19200916 ! protein targeting to membrane GO:0006612 75 36 0,000 0,17471812 0,19192282 ! aerobic respiration GO:0009060 56 36 0,000 0,17471812 0,19183657 ! cytokine production GO:0001816 68 36 0,000 0,17471812 0,19175039 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,17471812 0,19166428 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,17911088 0,19639492 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,17911088 0,19630681 ! sister chromatid segregation GO:0000819 65 37 0,000 0,17911088 0,19621878 ! odontogenesis GO:0042476 74 37 0,000 0,17911088 0,19613083 ! actomyosin structure organization GO:0031032 68 37 0,000 0,17911088 0,19604296 ! tissue remodeling GO:0048771 78 37 0,000 0,17911088 0,19595517 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,17911088 0,19586745 ! female gonad development GO:0008585 71 37 0,000 0,17911088 0,19577981 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,18348039 0,20046627 ! organic anion transport GO:0015711 82 38 0,000 0,18348039 0,20037666 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,18348039 0,20028713 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,18348039 0,20019767 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,18348039 0,2001083 GO:0006639|acylglycerol metabolic process, ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,18348039 0,200019 ! spermatid development GO:0007286 69 38 0,000 0,18348039 0,19992979 ! pigment metabolic process GO:0042440 87 38 0,000 0,18348039 0,19984065 ! neural tube formation GO:0001841 79 38 0,000 0,18348039 0,1997516 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,18782676 0,20439232 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,18782676 0,20430132 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,18782676 0,2042104 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,18782676 0,20411956 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,18782676 0,2040288 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,18782676 0,20393812 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,19215011 0,20853964 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,19215011 0,20844704 ! lipid homeostasis GO:0055088 75 40 0,000 0,19215011 0,20835452 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,19215011 0,20826208 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,19215011 0,20816972 ! RNA export from nucleus GO:0006405 61 41 0,000 0,19645058 0,21273438 ! mRNA catabolic process GO:0006402 79 41 0,000 0,19645058 0,21264012 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,19645058 0,21254595 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,19645058 0,21245186 ! gliogenesis GO:0042063 91 41 0,000 0,19645058 0,21235786 ! feeding behavior GO:0007631 69 41 0,000 0,19645058 0,21226394 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,19645058 0,2121701 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,19645058 0,21207634 ! spermatid differentiation GO:0048515 73 41 0,000 0,19645058 0,21198267 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,19645058 0,21188908 ! RNA modification GO:0009451 64 41 0,000 0,19645058 0,21179557 ! organic ether metabolic process GO:0018904 59 42 0,000 0,20072827 0,21631193 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,20072827 0,21621656 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,20072827 0,21612127 ! cytokinesis GO:0000910 84 42 0,000 0,20072827 0,21602606 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,20072827 0,21593094 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,2049833 0,22041119 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,2049833 0,22031422 ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,2049833 0,22021733 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,2049833 0,22012053 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,2049833 0,22002382 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,2049833 0,21992719 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,2049833 0,21983065 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,2049833 0,21973419 ! ion transmembrane transport GO:0034220 79 43 0,000 0,2049833 0,21963781 ! neuron migration GO:0001764 85 43 0,000 0,2049833 0,21954152 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,2049833 0,21944532 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,20921581 0,22387833 ! positive regulation of response to external stimulus GO:0032103 88 44 0,000 0,20921581 0,22378031 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,20921581 0,22368237 ! striated muscle contraction GO:0006941 85 44 0,000 0,20921581 0,22358452 ! phagocytosis GO:0006909 105 44 0,000 0,20921581 0,22348676 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,20921581 0,22338908 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,2134259 0,22778483 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,2134259 0,22768536 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! biopolymer methylation GO:0043414 91 45 0,000 0,2134259 0,22758598 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,2134259 0,22748668 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,2134259 0,22738747 ! polyol metabolic process GO:0019751 77 45 0,000 0,2134259 0,22728835 ! maintenance of location in cell GO:0051651 101 45 0,000 0,2134259 0,22718931 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,21761369 0,23154628 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,21761369 0,23144547 ! glycolysis GO:0006096 71 46 0,000 0,21761369 0,23134476 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,21761369 0,23124413 ! neural tube development GO:0021915 91 47 0,000 0,22177931 0,2355682 ! positive regulation of defense response GO:0031349 88 48 0,000 0,22592286 0,23986508 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,22592286 0,23976088 ! endosome transport GO:0016197 127 48 0,000 0,22592286 0,23965678 ! male sex differentiation GO:0046661 93 48 0,000 0,22592286 0,23955276 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,22592286 0,23944883 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,22592286 0,23934499 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,22592286 0,23924125 ! methylation GO:0032259 97 48 0,000 0,22592286 0,23913759 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,23004447 0,24339482 ! JNK cascade GO:0007254 106 49 0,000 0,23004447 0,24328945 ! protein homooligomerization GO:0051260 84 49 0,000 0,23004447 0,24318418 ! regulation of ion transport GO:0043269 86 50 0,000 0,23414425 0,24741107 ! endocrine system development GO:0035270 109 50 0,000 0,23414425 0,24730411 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,23414425 0,24719723 ! regulation of ossification GO:0030278 123 50 0,000 0,23414425 0,24709045 ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,23414425 0,24698376 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,23414425 0,24687717 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,23414425 0,24677066 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,23822231 0,25096037 ! viral infectious cycle GO:0019058 104 51 0,000 0,23822231 0,2508522 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,23822231 0,25074412 ! peptide metabolic process GO:0006518 80 51 0,000 0,23822231 0,25063613 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,24227877 0,25479425 ! Notch signaling pathway GO:0007219 111 52 0,000 0,24227877 0,25468461 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,24227877 0,25457507 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,24227877 0,25446562 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,24227877 0,25435627 ! amino acid activation GO:0043038 98 52 0,000 0,24227877 0,25424701 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,24631375 0,25837032 ! inner ear development GO:0048839 89 53 0,000 0,24631375 0,25825943 ! chromatin remodeling GO:0006338 122 53 0,000 0,24631375 0,25814864 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,24631375 0,25803794 ! regulation of translational initiation GO:0006446 87 54 0,000 0,25032735 0,26213018 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,25032735 0,26201787 ! neuromuscular process GO:0050905 107 54 0,000 0,25032735 0,26190566 ! membrane fusion GO:0006944 122 54 0,000 0,25032735 0,26179354 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,25032735 0,26168152 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,25032735 0,26156959 ! RNA catabolic process GO:0006401 103 55 0,000 0,25431969 0,26562761 ! cell recognition GO:0008037 98 55 0,000 0,25431969 0,2655141 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,25431969 0,26540068 ! glucose catabolic process GO:0006007 88 56 0,000 0,25829088 0,26942981 ! chloride transport GO:0006821 102 57 0,000 0,26224103 0,27343356 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,26224103 0,27331691 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,26617025 0,27729379 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,26617025 0,27717559 ! gastrulation GO:0007369 122 58 0,000 0,26617025 0,27705749 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,26617025 0,27693949 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,26617025 0,2768216 ! maintenance of location GO:0051235 124 58 0,000 0,26617025 0,2767038 ! nuclear export GO:0051168 110 59 0,000 0,27007866 0,28064746 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,27396637 0,28456626 ! regulation of endocytosis GO:0030100 104 60 0,000 0,27396637 0,28444532 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,27396637 0,28432448 ! adult behavior GO:0030534 104 60 0,000 0,27396637 0,28420375 ! kidney development GO:0001822 133 60 0,000 0,27396637 0,28408312 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,27783347 0,2879708 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,27783347 0,28784867 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,27783347 0,28772665 ! proton transport GO:0015992 117 61 0,000 0,27783347 0,28760473 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,27783347 0,28748292 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,28168009 0,29133974 ! tRNA processing GO:0008033 102 62 0,000 0,28168009 0,29121644 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,28550632 0,29504735 ! mesoderm development GO:0007498 128 63 0,000 0,28550632 0,2949226 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,28550632 0,29479795 ! hydrogen transport GO:0006818 121 64 0,000 0,28931228 0,29860157 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,28931228 0,29847547 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,29309808 0,30225353 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,29309808 0,30212599 GO:0048609|reproductive process in a multicellular organism, ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,29309808 0,30199857 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,29686381 0,3057497 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,29686381 0,30562086 ! gonad development GO:0008406 115 66 0,000 0,29686381 0,30549212 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,30060959 0,30921652 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 0,000 0,30060959 0,30908638 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,30060959 0,30895634 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,30060959 0,30882642 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,30060959 0,30869661 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,30433552 0,31239146 ! hexose catabolic process GO:0019320 113 68 0,000 0,30433552 0,31226026 ! extracellular matrix organization GO:0030198 146 68 0,000 0,30433552 0,31212917 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,30433552 0,31199818 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,30433552 0,31186731 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,3080417 0,31553286 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,3080417 0,31540062 ! single fertilization GO:0007338 83 69 0,000 0,3080417 0,31526849 ! cell redox homeostasis GO:0045454 114 70 0,000 0,31172825 0,31890792 ! activation of immune response GO:0002253 120 70 0,000 0,31172825 0,31877443 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,31172825 0,31864105 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,31539525 0,32225454 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,31539525 0,32211982 ! appendage morphogenesis GO:0035107 150 72 0,000 0,31904282 0,32570899 GO:0035108|limb morphogenesis, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,31904282 0,32557294 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,31904282 0,325437 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,31904282 0,32530118 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,31904282 0,32516546 ! appendage development GO:0048736 151 73 0,000 0,32267106 0,32872619 GO:0060173|limb development, ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,32267106 0,32858917 ! acute inflammatory response GO:0002526 118 74 0,000 0,32628007 0,33212592 ! amino acid transport GO:0006865 148 74 0,000 0,32628007 0,3319876 ! rhythmic process GO:0048511 142 75 0,000 0,32986995 0,33550054 ! amine catabolic process GO:0009310 136 77 0,000 0,33699273 0,34260227 ! neurotransmitter transport GO:0006836 142 77 0,000 0,33699273 0,34245975 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,33699273 0,34231736 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,33699273 0,34217508 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,33699273 0,34203292 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,34052583 0,34547533 ! antigen processing and presentation GO:0019882 117 78 0,000 0,34052583 0,34533192 ! fertilization GO:0009566 99 78 0,000 0,34052583 0,34518863 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,3440402 0,34860647 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,34753594 0,35200261 ! muscle cell differentiation GO:0042692 178 81 0,000 0,35101315 0,35537717 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,35791236 0,36221205 ! exocytosis GO:0006887 153 83 0,000 0,35791236 0,36206207 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,35791236 0,36191221 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,35791236 0,36176247 ! inorganic anion transport GO:0015698 156 83 0,000 0,35791236 0,36161286 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,36473861 0,36835735 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,36473861 0,36820513 ! regulation of lyase activity GO:0051339 169 86 0,000 0,36812462 0,37146982 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,37149267 0,37471371 ! alcohol catabolic process GO:0046164 142 87 0,000 0,37149267 0,37455906 ! nucleosome assembly GO:0006334 126 87 0,000 0,37149267 0,37440454 ! cellular respiration GO:0045333 143 88 0,000 0,37484287 0,37762521 ! amine biosynthetic process GO:0009309 146 88 0,000 0,37484287 0,37746955 ! sensory perception of smell GO:0007608 117 88 0,000 0,37484287 0,37731402 ! chromatin assembly GO:0031497 128 88 0,000 0,37484287 0,37715862 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,37484287 0,37700334 ! cellular defense response GO:0006968 123 89 0,000 0,3781753 0,38019846 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,38149006 0,38337319 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,38806694 0,38982218 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,39132925 0,39293768 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,39132925 0,39277624 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,39457426 0,3958706 ! sterol metabolic process GO:0016125 166 94 0,000 0,39457426 0,39570809 ! regulation of defense response GO:0031347 171 95 0,000 0,39780206 0,39878146 ! nucleosome organization GO:0034728 143 95 0,000 0,39780206 0,3986179 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,39780206 0,39845446 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,39780206 0,39829116 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,40420639 0,40453757 ! mRNA transport GO:0051028 185 100 0,000 0,41368608 0,41385548 ! positive regulation of immune response GO:0050778 175 100 0,000 0,41368608 0,41368608