pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6533-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! cellular response to hormone stimulus GO:0032870 167 82 8,000 7,152E-11 1,721E-07 ! positive regulation of MAP kinase activity GO:0043406 160 93 7,000 6,036E-09 7,261E-06 ! regulation of protein export from nucleus GO:0046825 10 7 3,000 1,045E-08 8,382E-06 ! organ growth GO:0035265 15 7 3,000 1,045E-08 6,286E-06 ! negative regulation of peptide secretion GO:0002792 10 7 3,000 1,045E-08 5,029E-06 GO:0046676|negative regulation of insulin secretion, ! carbohydrate homeostasis GO:0033500 53 38 5,000 1,234E-08 4,947E-06 GO:0042593|glucose homeostasis, ! positive regulation of hormone secretion GO:0046887 32 19 4,000 1,366E-08 4,695E-06 ! regulation of growth hormone secretion GO:0060123 16 8 3,000 2,083E-08 6,266E-06 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 3,000 3,738E-08 9,992E-06 ! regulation of insulin secretion GO:0050796 37 25 4,000 6,116E-08 1,472E-05 ! insulin receptor signaling pathway GO:0008286 64 26 4,000 7,547E-08 1,651E-05 ! regulation of peptide secretion GO:0002791 47 29 4,000 1,349E-07 2,704E-05 ! DNA damage response, signal transduction GO:0042770 128 60 5,000 2,074E-07 3,839E-05 ! DNA damage checkpoint GO:0000077 71 33 4,000 2,659E-07 4,57E-05 ! activation of MAPK activity GO:0000187 115 67 5,000 4,036E-07 6,474E-05 ! DNA integrity checkpoint GO:0031570 75 36 4,000 4,182E-07 6,288E-05 ! cellular response to insulin stimulus GO:0032869 82 37 4,000 4,819E-07 6,82E-05 ! negative regulation of hormone secretion GO:0046888 25 17 3,000 6,878E-07 9,193E-05 ! regulation of hormone secretion GO:0046883 62 40 4,000 7,201E-07 9,118E-05 ! response to insulin stimulus GO:0032868 95 46 4,000 1,47E-06 1,768E-04 ! positive regulation of growth GO:0045927 90 52 4,000 2,731E-06 3,129E-04 ! response to UV GO:0009411 104 53 4,000 3,006E-06 3,287E-04 ! regulation of multicellular organism growth GO:0040014 85 55 4,000 3,619E-06 3,786E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 4,038E-06 4,048E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 4,038E-06 3,886E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 4,000 4,327E-06 4,004E-04 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 3,000 4,909E-06 4,374E-04 ! positive regulation of secretion GO:0051047 95 59 4,000 5,139E-06 4,416E-04 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 5,587E-06 4,635E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 6,038E-06 4,843E-04 ! response to peptide hormone stimulus GO:0043434 122 61 4,000 6,065E-06 4,708E-04 ! negative regulation of BMP signaling pathway GO:0030514 19 10 2,000 8,6E-06 6,466E-04 ! triglyceride metabolic process GO:0006641 43 31 3,000 8,687E-06 6,333E-04 ! cell cycle checkpoint GO:0000075 137 69 4,000 1,115E-05 7,893E-04 ! urogenital system development GO:0001655 137 69 4,000 1,115E-05 7,667E-04 ! negative regulation of secretion GO:0051048 63 35 3,000 1,427E-05 9,536E-04 ! neutral lipid metabolic process GO:0006638 50 35 3,000 1,427E-05 9,278E-04 GO:0006639|acylglycerol metabolic process, ! positive regulation of cell growth GO:0030307 22 12 2,000 1,567E-05 9,921E-04 ! glycerol ether metabolic process GO:0006662 53 37 3,000 1,788E-05 1,103E-03 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 4,000 2,163E-05 1,301E-03 ! organic ether metabolic process GO:0018904 55 39 3,000 2,212E-05 1,298E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 2,000 2,577E-05 1,476E-03 GO:0060675|ureteric bud morphogenesis, ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 2,577E-05 1,442E-03 ! hormone-mediated signaling GO:0009755 74 41 3,000 2,706E-05 1,48E-03 ! regulation of intracellular protein transport GO:0033157 80 42 3,000 2,981E-05 1,594E-03 ! positive regulation of cell size GO:0045793 27 15 2,000 3,211E-05 1,679E-03 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 3,000 3,276E-05 1,677E-03 ! regulation of protein transport GO:0051223 154 87 4,000 3,452E-05 1,73E-03 GO:0070201|regulation of establishment of protein localization, ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 3,93E-05 1,93E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 4,29E-05 2,064E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 4,29E-05 2,024E-03 ! regulation of gene-specific transcription GO:0032583 96 46 3,000 4,29E-05 1,985E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 4,769E-05 2,165E-03 ! regulation of BMP signaling pathway GO:0030510 32 18 2,000 5,705E-05 2,542E-03 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 2,000 5,705E-05 2,496E-03 ! hormone metabolic process GO:0042445 157 97 4,000 5,821E-05 2,501E-03 ! regulation of protein localization GO:0032880 176 97 4,000 5,821E-05 2,457E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 7,921E-05 3,286E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 7,921E-05 3,23E-03 ! heart morphogenesis GO:0003007 97 55 3,000 8,707E-05 3,492E-03 ! regulation of DNA replication GO:0006275 101 56 3,000 9,346E-05 3,686E-03 ! regulation of intracellular transport GO:0032386 101 57 3,000 1,002E-04 3,888E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 1,063E-04 4,062E-03 ! ureteric bud development GO:0001657 43 22 2,000 1,063E-04 3,998E-03 ! regulation of bone mineralization GO:0030500 49 23 2,000 1,219E-04 4,513E-03 ! kidney development GO:0001822 122 60 3,000 1,225E-04 4,465E-03 ! protein import into nucleus, translocation GO:0000060 46 24 2,000 1,389E-04 4,988E-03 ! protein tetramerization GO:0051262 52 24 2,000 1,389E-04 4,915E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 1,574E-04 5,487E-03 ! negative regulation of DNA replication GO:0008156 42 25 2,000 1,574E-04 5,409E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 1,574E-04 5,333E-03 ! regulation of biomineral formation GO:0070167 51 25 2,000 1,574E-04 5,259E-03 ! multicellular organism reproduction GO:0032504 111 64 3,000 1,575E-04 5,192E-03 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of cell motion GO:0051272 146 64 3,000 1,575E-04 5,122E-03 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 1,75E-04 5,613E-03 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 1,000 1,75E-04 5,539E-03 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 1,75E-04 5,467E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 1,75E-04 5,397E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 1,75E-04 5,329E-03 ! parathyroid gland development GO:0060017 13 5 1,000 1,75E-04 5,262E-03 ! microvillus organization GO:0032528 7 5 1,000 1,75E-04 5,197E-03 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 1,000 1,75E-04 5,134E-03 ! positive regulation of filopodium assembly GO:0051491 14 5 1,000 1,75E-04 5,072E-03 GO:0051489|regulation of filopodium assembly, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 1,75E-04 5,012E-03 ! porphyrin catabolic process GO:0006787 12 5 1,000 1,75E-04 4,953E-03 GO:0033015|tetrapyrrole catabolic process, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 1,774E-04 4,962E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 1,882E-04 5,205E-03 ! lung development GO:0030324 144 67 3,000 1,882E-04 5,145E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 1,989E-04 5,377E-03 ! negative regulation of kinase activity GO:0033673 131 68 3,000 1,993E-04 5,328E-03 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 2,221E-04 5,872E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 2,221E-04 5,808E-03 ! respiratory tube development GO:0030323 150 70 3,000 2,229E-04 5,768E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 2,47E-04 6,321E-03 ! negative regulation of transferase activity GO:0051348 140 72 3,000 2,485E-04 6,294E-03 ! respiratory system development GO:0060541 153 72 3,000 2,485E-04 6,229E-03 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 1,000 2,617E-04 6,492E-03 ! male sex determination GO:0030238 15 6 1,000 2,617E-04 6,426E-03 ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 2,617E-04 6,361E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 2,617E-04 6,297E-03 ! metanephros development GO:0001656 74 32 2,000 3,321E-04 7,912E-03 ! BMP signaling pathway GO:0030509 64 32 2,000 3,321E-04 7,835E-03 ! positive regulation of phosphorylation GO:0042327 129 79 3,000 3,548E-04 8,288E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 3,654E-04 8,453E-03 ! SMAD protein complex assembly GO:0007183 12 7 1,000 3,654E-04 8,373E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 3,654E-04 8,294E-03 ! oxaloacetate metabolic process GO:0006107 10 7 1,000 3,654E-04 8,216E-03 ! wound healing, spreading of epidermal cells GO:0035313 14 7 1,000 3,654E-04 8,14E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 3,654E-04 8,066E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 3,654E-04 7,992E-03 ! transcription from RNA polymerase I promoter GO:0006360 13 7 1,000 3,654E-04 7,92E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 3,654E-04 7,85E-03 ! transcription termination GO:0006353 13 7 1,000 3,654E-04 7,78E-03 ! response to tumor cell GO:0002347 13 7 1,000 3,654E-04 7,712E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 3,654E-04 7,645E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 3,000 3,903E-04 8,096E-03 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 4,342E-04 8,93E-03 ! negative regulation of hydrolase activity GO:0051346 62 35 2,000 4,342E-04 8,854E-03 ! negative regulation of transport GO:0051051 153 84 3,000 4,483E-04 9,064E-03 ! succinate metabolic process GO:0006105 14 8 1,000 4,859E-04 9,741E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 4,859E-04 9,661E-03 ! ER overload response GO:0006983 12 8 1,000 4,859E-04 9,582E-03 ! positive regulation of insulin secretion GO:0032024 15 8 1,000 4,859E-04 9,504E-03 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 1,000 4,859E-04 9,427E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 4,859E-04 9,352E-03 ! ossification GO:0001503 188 90 3,000 5,822E-04 0,01111813 ! bone development GO:0060348 189 91 3,000 6,07E-04 0,01150041 ! regulation of developmental growth GO:0048638 15 9 1,000 6,229E-04 0,01170948 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 6,229E-04 0,01161871 ! artery development GO:0060840 24 9 1,000 6,229E-04 0,01152933 GO:0048844|artery morphogenesis, ! regulation of glycolysis GO:0006110 21 9 1,000 6,229E-04 0,01144132 ! keratinocyte proliferation GO:0043616 14 9 1,000 6,229E-04 0,01135465 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 1,000 6,229E-04 0,01126927 ! phosphagen metabolic process GO:0006599 12 9 1,000 6,229E-04 0,01118517 GO:0006600|creatine metabolic process, ! retinol metabolic process GO:0042572 18 9 1,000 6,229E-04 0,01110232 ! motor axon guidance GO:0008045 16 9 1,000 6,229E-04 0,01102069 ! protein heterooligomerization GO:0051291 16 9 1,000 6,229E-04 0,01094024 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 7,138E-04 0,01244443 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 7,718E-04 0,01335975 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 7,765E-04 0,01334531 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 7,765E-04 0,01325067 ! SMAD protein nuclear translocation GO:0007184 20 10 1,000 7,765E-04 0,01315735 ! positive regulation of survival gene product expression GO:0045885 23 10 1,000 7,765E-04 0,01306534 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 7,765E-04 0,01297461 ! regulation of gliogenesis GO:0014013 23 10 1,000 7,765E-04 0,01288513 GO:0045685|regulation of glial cell differentiation, ! regulation of protein kinase B signaling cascade GO:0051896 26 10 1,000 7,765E-04 0,01279688 ! negative regulation of MAPKKK cascade GO:0043409 20 10 1,000 7,765E-04 0,01270982 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 7,765E-04 0,01262395 GO:0043470|regulation of carbohydrate catabolic process, ! localization within membrane GO:0051668 20 10 1,000 7,765E-04 0,01253922 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 7,989E-04 0,01281464 ! interphase GO:0051325 213 98 3,000 8,021E-04 0,01277992 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 2,000 8,547E-04 0,01352975 ! branching morphogenesis of a tube GO:0048754 97 45 2,000 9,13E-04 0,01435727 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 9,465E-04 0,0147872 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 9,465E-04 0,0146918 ! negative regulation of proteolysis GO:0045861 25 11 1,000 9,465E-04 0,01459762 ! regulation of intracellular pH GO:0051453 19 11 1,000 9,465E-04 0,01450464 ! positive regulation of peptide secretion GO:0002793 22 11 1,000 9,465E-04 0,01441284 ! thymus development GO:0048538 27 11 1,000 9,465E-04 0,01432219 ! germ cell migration GO:0008354 25 11 1,000 9,465E-04 0,01423268 ! cardiac cell differentiation GO:0035051 31 11 1,000 9,465E-04 0,01414428 ! T cell receptor signaling pathway GO:0050852 23 11 1,000 9,465E-04 0,01405697 ! regulation of embryonic development GO:0045995 27 11 1,000 9,465E-04 0,01397073 ! response to calcium ion GO:0051592 81 47 2,000 1,037E-03 0,01521207 ! regulation of JNK cascade GO:0046328 94 47 2,000 1,037E-03 0,01511988 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,103E-03 0,01598161 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 2,000 1,103E-03 0,01588591 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 1,103E-03 0,01579135 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 1,000 1,133E-03 0,01612506 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 1,133E-03 0,0160302 ! virus-host interaction GO:0019048 29 12 1,000 1,133E-03 0,01593646 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,133E-03 0,01584381 ! cartilage condensation GO:0001502 20 12 1,000 1,133E-03 0,01575222 ! protein complex disassembly GO:0043241 27 12 1,000 1,133E-03 0,01566169 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 1,000 1,133E-03 0,0155722 ! histone acetylation GO:0016573 26 12 1,000 1,133E-03 0,01548372 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,133E-03 0,01539624 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 1,133E-03 0,01530975 GO:0042130|negative regulation of T cell proliferation, ! regulation of ossification GO:0030278 117 50 2,000 1,242E-03 0,01669252 ! negative regulation of immune system process GO:0002683 95 50 2,000 1,242E-03 0,01659978 ! embryonic skeletal system development GO:0048706 85 51 2,000 1,315E-03 0,01748612 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 1,315E-03 0,01739005 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 2,000 1,315E-03 0,01729502 ! response to X-ray GO:0010165 25 13 1,000 1,335E-03 0,01745506 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 1,335E-03 0,01736071 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! nucleoside triphosphate catabolic process GO:0009143 21 13 1,000 1,335E-03 0,01726737 ! regulation of cellular pH GO:0030641 22 13 1,000 1,335E-03 0,01717503 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,335E-03 0,01708367 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 1,392E-03 0,01771684 ! cartilage development GO:0051216 90 52 2,000 1,392E-03 0,01762359 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,553E-03 0,01956381 ! retina development in camera-type eye GO:0060041 27 14 1,000 1,553E-03 0,01946191 ! palate development GO:0060021 31 14 1,000 1,553E-03 0,01936107 ! negative regulation of caspase activity GO:0043154 22 14 1,000 1,553E-03 0,01926128 ! response to gamma radiation GO:0010332 28 14 1,000 1,553E-03 0,0191625 ! positive regulation of bone mineralization GO:0030501 29 14 1,000 1,553E-03 0,01906473 ! protein-chromophore linkage GO:0018298 19 14 1,000 1,553E-03 0,01896796 ! heterophilic cell adhesion GO:0007157 39 15 1,000 1,787E-03 0,02171554 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 1,787E-03 0,02160642 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,787E-03 0,02149839 ! positive regulation of biomineral formation GO:0070169 30 15 1,000 1,787E-03 0,02139143 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 1,787E-03 0,02128553 ! regulation of bone remodeling GO:0046850 137 57 2,000 1,815E-03 0,02150704 ! positive regulation of cell migration GO:0030335 126 57 2,000 1,815E-03 0,02140162 ! regulation of tissue remodeling GO:0034103 140 58 2,000 1,908E-03 0,02239022 ! skeletal system morphogenesis GO:0048705 105 59 2,000 2,004E-03 0,02340342 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 2,037E-03 0,02367332 ! activation of MAPKK activity GO:0000186 35 16 1,000 2,037E-03 0,0235595 ! negative regulation of immune response GO:0050777 35 16 1,000 2,037E-03 0,02344678 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 2,037E-03 0,02333513 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 2,037E-03 0,02322454 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 2,302E-03 0,02612482 ! regulation of survival gene product expression GO:0045884 33 17 1,000 2,302E-03 0,02600217 ! cardiac muscle tissue development GO:0048738 31 17 1,000 2,302E-03 0,02588066 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 2,302E-03 0,02576029 ! genitalia development GO:0048806 30 17 1,000 2,302E-03 0,02564103 ! branched chain family amino acid metabolic process GO:0009081 33 17 1,000 2,302E-03 0,02552287 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 1,000 2,302E-03 0,02540579 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 2,583E-03 0,02837266 ! protein amino acid ADP-ribosylation GO:0006471 33 18 1,000 2,583E-03 0,02824369 ! memory GO:0007613 31 18 1,000 2,583E-03 0,02811589 ! response to retinoic acid GO:0032526 26 18 1,000 2,583E-03 0,02798924 ! cell-substrate junction assembly GO:0007044 54 18 1,000 2,583E-03 0,02786373 ! vitamin transport GO:0051180 27 18 1,000 2,583E-03 0,02773934 ! regulation of immunoglobulin production GO:0002637 43 18 1,000 2,583E-03 0,02761605 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 2,583E-03 0,02749386 ! skin development GO:0043588 36 19 1,000 2,878E-03 0,03050884 ! lipid phosphorylation GO:0046834 35 19 1,000 2,878E-03 0,03037503 ! cellular response to unfolded protein GO:0034620 33 19 1,000 2,878E-03 0,03024239 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 1,000 2,878E-03 0,0301109 ! heme metabolic process GO:0042168 36 19 1,000 2,878E-03 0,02998055 ! neuromuscular junction development GO:0007528 34 19 1,000 2,878E-03 0,02985133 ! prostaglandin metabolic process GO:0006693 37 19 1,000 2,878E-03 0,02972321 GO:0006692|prostanoid metabolic process, ! proximal/distal pattern formation GO:0009954 32 19 1,000 2,878E-03 0,02959619 ! embryonic organ morphogenesis GO:0048562 26 19 1,000 2,878E-03 0,02947024 ! regulation of cellular response to stress GO:0080135 128 67 2,000 2,881E-03 0,0293754 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 2,881E-03 0,02925146 ! negative regulation of cell growth GO:0030308 132 67 2,000 2,881E-03 0,02912855 ! negative regulation of cell size GO:0045792 134 69 2,000 3,132E-03 0,03153147 ! positive regulation of ossification GO:0045778 47 20 1,000 3,189E-03 0,0319743 ! protein amino acid acetylation GO:0006473 39 20 1,000 3,189E-03 0,03184163 ! response to vitamin GO:0033273 31 20 1,000 3,189E-03 0,03171005 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 3,189E-03 0,03157956 GO:0010675|regulation of cellular carbohydrate metabolic process, ! retinoid metabolic process GO:0001523 32 20 1,000 3,189E-03 0,03145013 GO:0016101|diterpenoid metabolic process, ! cellular response to starvation GO:0009267 33 20 1,000 3,189E-03 0,03132176 ! camera-type eye morphogenesis GO:0048593 42 20 1,000 3,189E-03 0,03119444 ! negative regulation of T cell activation GO:0050868 40 20 1,000 3,189E-03 0,03106815 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 3,189E-03 0,03094287 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 3,396E-03 0,03281422 ! cellular macromolecular complex disassembly GO:0034623 43 21 1,000 3,515E-03 0,03383308 ! cell aging GO:0007569 44 21 1,000 3,515E-03 0,03369829 ! collagen fibril organization GO:0030199 59 21 1,000 3,515E-03 0,03356457 ! positive regulation of inflammatory response GO:0050729 35 21 1,000 3,515E-03 0,0334319 ! vitamin A metabolic process GO:0006776 33 21 1,000 3,515E-03 0,03330028 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 3,515E-03 0,03316969 ! terpenoid metabolic process GO:0006721 37 21 1,000 3,515E-03 0,03304012 ! regulation of caspase activity GO:0043281 122 72 2,000 3,533E-03 0,0330739 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 3,533E-03 0,0329457 ! learning or memory GO:0007611 147 73 2,000 3,673E-03 0,03412067 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 3,817E-03 0,03531763 ! eye development GO:0001654 143 74 2,000 3,817E-03 0,03518231 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 3,856E-03 0,03541416 ! positive regulation of bone remodeling GO:0046852 51 22 1,000 3,856E-03 0,03527951 GO:0034105|positive regulation of tissue remodeling, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 3,856E-03 0,03514587 ! positive regulation of B cell activation GO:0050871 38 22 1,000 3,856E-03 0,03501325 ! regulation of catabolic process GO:0009894 161 76 2,000 4,114E-03 0,03720933 ! positive regulation of DNA replication GO:0045740 43 23 1,000 4,212E-03 0,03795595 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 4,212E-03 0,03781433 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 4,212E-03 0,03767375 ! gluconeogenesis GO:0006094 33 23 1,000 4,212E-03 0,03753422 ! leukocyte adhesion GO:0007159 50 23 1,000 4,212E-03 0,03739572 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 1,000 4,212E-03 0,03725824 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! sex determination GO:0007530 47 23 1,000 4,212E-03 0,03712176 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 4,212E-03 0,03698628 ! negative regulation of catabolic process GO:0009895 50 23 1,000 4,212E-03 0,03685178 ! protein oligomerization GO:0051259 139 78 2,000 4,425E-03 0,03857154 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 4,582E-03 0,03980199 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 4,582E-03 0,03965881 ! digestive system process GO:0022600 39 24 1,000 4,582E-03 0,03951667 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 4,582E-03 0,03937554 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 4,582E-03 0,03923541 ! porphyrin metabolic process GO:0006778 46 24 1,000 4,582E-03 0,03909628 GO:0033013|tetrapyrrole metabolic process, ! activation of protein kinase activity GO:0032147 147 79 2,000 4,585E-03 0,03898331 ! regulation of peptidase activity GO:0052547 134 79 2,000 4,585E-03 0,03884604 ! response to metal ion GO:0010038 140 80 2,000 4,749E-03 0,04009547 ! protein import into nucleus GO:0006606 158 80 2,000 4,749E-03 0,03995527 ! nuclear import GO:0051170 161 81 2,000 4,917E-03 0,04122158 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 4,967E-03 0,0414963 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 4,967E-03 0,04135271 ! myelination GO:0042552 45 25 1,000 4,967E-03 0,04121012 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 4,967E-03 0,0410685 ! response to starvation GO:0042594 42 25 1,000 4,967E-03 0,04092786 ! negative regulation of cell development GO:0010721 73 25 1,000 4,967E-03 0,04078817 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 4,967E-03 0,04064944 ! somitogenesis GO:0001756 43 25 1,000 4,967E-03 0,04051164 ! positive regulation of protein secretion GO:0050714 36 25 1,000 4,967E-03 0,04037478 ! cellular response to nutrient levels GO:0031669 41 25 1,000 4,967E-03 0,04023884 ! response to nutrient GO:0007584 125 82 2,000 5,088E-03 0,04108217 ! pyruvate metabolic process GO:0006090 38 26 1,000 5,366E-03 0,04318156 ! macromolecular complex disassembly GO:0032984 53 26 1,000 5,366E-03 0,04303762 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 5,366E-03 0,04289464 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 5,366E-03 0,04275261 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 5,366E-03 0,04261151 ! negative regulation of growth GO:0045926 155 84 2,000 5,441E-03 0,04306572 ! neuron fate commitment GO:0048663 48 27 1,000 5,78E-03 0,04559313 ! positive regulation of cell projection organization GO:0031346 58 27 1,000 5,78E-03 0,04544413 ! protein amino acid acylation GO:0043543 55 27 1,000 5,78E-03 0,04529611 ! fat cell differentiation GO:0045444 50 27 1,000 5,78E-03 0,04514904 ! mitochondrial membrane organization GO:0007006 57 27 1,000 5,78E-03 0,04500293 ! base-excision repair GO:0006284 41 27 1,000 5,78E-03 0,04485776 ! fat-soluble vitamin metabolic process GO:0006775 40 27 1,000 5,78E-03 0,04471352 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 5,78E-03 0,04457021 ! response to inorganic substance GO:0010035 153 86 2,000 5,809E-03 0,04465199 ! tube morphogenesis GO:0035239 176 86 2,000 5,809E-03 0,04450978 ! mitochondrion organization GO:0007005 148 86 2,000 5,809E-03 0,04436848 ! protein localization in nucleus GO:0034504 176 87 2,000 5,998E-03 0,04566838 ! positive regulation of protein modification process GO:0031401 136 88 2,000 6,191E-03 0,04698779 ! gland development GO:0048732 206 88 2,000 6,191E-03 0,04684003 ! regulation of pH GO:0006885 43 29 1,000 6,649E-03 0,05014649 ! immune response-activating signal transduction GO:0002757 47 29 1,000 6,649E-03 0,04998979 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 6,649E-03 0,04983405 ! tissue homeostasis GO:0001894 48 29 1,000 6,649E-03 0,04967929 GO:0048871|multicellular organismal homeostasis, ! cell junction assembly GO:0034329 78 30 1,000 7,104E-03 0,05291747 ! negative regulation of protein kinase cascade GO:0010741 68 30 1,000 7,104E-03 0,05275415 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 7,104E-03 0,05259183 ! ensheathment of neurons GO:0007272 57 30 1,000 7,104E-03 0,0524305 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 51 30 1,000 7,104E-03 0,05227016 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 7,104E-03 0,0521108 ! eye morphogenesis GO:0048592 60 30 1,000 7,104E-03 0,05195241 ! regulation of B cell activation GO:0050864 50 30 1,000 7,104E-03 0,05179498 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 7,573E-03 0,05504842 ! regulation of Rho protein signal transduction GO:0035023 213 95 2,000 7,644E-03 0,05539779 ! response to ionizing radiation GO:0010212 65 32 1,000 8,056E-03 0,05820567 ! response to mechanical stimulus GO:0009612 57 32 1,000 8,056E-03 0,0580314 ! hexose biosynthetic process GO:0019319 48 32 1,000 8,056E-03 0,05785817 ! peripheral nervous system development GO:0007422 64 32 1,000 8,056E-03 0,05768597 ! positive regulation of catabolic process GO:0009896 64 32 1,000 8,056E-03 0,0575148 ! post-embryonic development GO:0009791 69 33 1,000 8,552E-03 0,06087702 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 8,552E-03 0,06069744 ! positive regulation of neurogenesis GO:0050769 67 33 1,000 8,552E-03 0,06051892 ! skeletal muscle tissue development GO:0007519 186 99 2,000 8,558E-03 0,06038041 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 2,000 8,796E-03 0,06187761 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 9,062E-03 0,06356435 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 9,062E-03 0,06337957 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 9,585E-03 0,06684238 ! odontogenesis GO:0042476 66 35 1,000 9,585E-03 0,06664919 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 9,585E-03 0,06645712 ! calcium-mediated signaling GO:0019722 62 35 1,000 9,585E-03 0,06626615 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 0,01012065 0,06977159 ! cell junction organization GO:0034330 86 36 1,000 0,01012065 0,06957225 ! positive regulation of cell development GO:0010720 80 36 1,000 0,01012065 0,06937404 ! regulation of proteolysis GO:0030162 72 36 1,000 0,01012065 0,06917695 ! embryonic organ development GO:0048568 57 36 1,000 0,01012065 0,06898098 ! monosaccharide biosynthetic process GO:0046364 52 36 1,000 0,01012065 0,06878612 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,01012065 0,06859236 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,0106697 0,07211036 ! pigment metabolic process GO:0042440 80 37 1,000 0,0106697 0,07190837 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,01123165 0,0754842 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,01123165 0,07527394 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,01123165 0,07506484 GO:0046660|female sex differentiation, ! nucleotide catabolic process GO:0009166 61 38 1,000 0,01123165 0,07485691 ! isoprenoid metabolic process GO:0006720 66 38 1,000 0,01123165 0,07465012 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,01123165 0,07444447 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 1,000 0,01180639 0,07803893 ! learning GO:0007612 77 39 1,000 0,01180639 0,07782512 ! segmentation GO:0035282 67 39 1,000 0,01180639 0,07761248 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,01180639 0,07740101 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 0,0123938 0,08103122 ! feeding behavior GO:0007631 59 40 1,000 0,0123938 0,08081162 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,0123938 0,08059321 ! mesenchymal cell development GO:0014031 87 40 1,000 0,0123938 0,08037598 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! protein amino acid N-linked glycosylation GO:0006487 65 41 1,000 0,01299377 0,08404038 ! cellular amide metabolic process GO:0043603 67 41 1,000 0,01299377 0,08381507 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,01299377 0,08359096 ! T cell differentiation GO:0030217 81 41 1,000 0,01299377 0,08336805 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,01299377 0,08314633 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,01299377 0,08292578 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01360619 0,08660448 GO:0090047|positive regulation of transcription regulator activity, ! alcohol biosynthetic process GO:0046165 59 42 1,000 0,01360619 0,08637597 ! regulation of protein secretion GO:0050708 71 42 1,000 0,01360619 0,08614866 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,01423093 0,08986779 ! double-strand break repair GO:0006302 81 44 1,000 0,0148679 0,09364439 ! B cell differentiation GO:0030183 107 44 1,000 0,0148679 0,09339989 ! JAK-STAT cascade GO:0007259 71 44 1,000 0,0148679 0,09315666 ! icosanoid metabolic process GO:0006690 80 45 1,000 0,01551696 0,09697093 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 0,01551696 0,09671971 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,01617802 0,10057962 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,01617802 0,10032039 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,01685096 0,10422469 ! positive regulation of defense response GO:0031349 76 47 1,000 0,01685096 0,10395744 ! mitochondrial transport GO:0006839 82 48 1,000 0,01753567 0,10790489 ! Notch signaling pathway GO:0007219 96 48 1,000 0,01753567 0,10762963 ! cellular component disassembly GO:0022411 86 48 1,000 0,01753567 0,10735576 ! activation of caspase activity GO:0006919 84 48 1,000 0,01753567 0,10708328 ! regulation of inflammatory response GO:0050727 75 48 1,000 0,01753567 0,10681219 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,01753567 0,10654246 ! regulation of action potential GO:0001508 95 49 1,000 0,01823204 0,11049441 ! unsaturated fatty acid metabolic process GO:0033559 86 49 1,000 0,01823204 0,11021679 ! endocrine system development GO:0035270 104 49 1,000 0,01823204 0,10994056 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,01893996 0,11392386 ! histone modification GO:0016570 91 50 1,000 0,01893996 0,11363976 ! positive regulation of binding GO:0051099 78 51 1,000 0,01965933 0,11766255 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,01965933 0,11737058 ! chromatin remodeling GO:0006338 109 51 1,000 0,01965933 0,11708006 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,01965933 0,11679097 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,02039003 0,12083354 ! covalent chromatin modification GO:0016569 101 52 1,000 0,02039003 0,12053665 ! synapse organization GO:0050808 85 52 1,000 0,02039003 0,12024122 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02090874 0,12299861 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02090874 0,12269861 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02090874 0,12240008 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02090874 0,12210299 ! neuron fate determination GO:0048664 7 5 0,000 0,02090874 0,12180734 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02090874 0,12151312 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02090874 0,12122032 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02090874 0,12092892 ! polyol transport GO:0015791 12 5 0,000 0,02090874 0,12063892 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02090874 0,12035031 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02090874 0,12006308 ! response to superoxide GO:0000303 10 5 0,000 0,02090874 0,11977722 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02090874 0,11949271 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02090874 0,11920955 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02090874 0,11892773 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02090874 0,11864724 ! female meiosis GO:0007143 7 5 0,000 0,02090874 0,11836807 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02090874 0,11809021 ! cobalt ion transport GO:0006824 11 5 0,000 0,02090874 0,11781366 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02090874 0,11753839 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02090874 0,11726441 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02090874 0,1169917 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02090874 0,11672026 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02090874 0,11645007 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02090874 0,11618113 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02090874 0,11591344 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02090874 0,11564697 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02090874 0,11538172 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02090874 0,11511769 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02090874 0,11485487 ! negative chemotaxis GO:0050919 14 5 0,000 0,02090874 0,11459324 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02090874 0,1143328 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02090874 0,11407354 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02090874 0,11381545 ! behavioral response to pain GO:0048266 9 5 0,000 0,02090874 0,11355854 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02090874 0,11330277 ! Notch receptor processing GO:0007220 8 5 0,000 0,02090874 0,11304816 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02090874 0,11279469 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02090874 0,11254235 ! micturition GO:0060073 9 5 0,000 0,02090874 0,11229114 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02090874 0,11204105 ! copulation GO:0007620 9 5 0,000 0,02090874 0,11179207 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02090874 0,11154419 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02090874 0,11129741 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02090874 0,11105172 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02090874 0,11080712 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02090874 0,11056358 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02090874 0,11032112 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02090874 0,11007972 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02090874 0,10983937 ! grooming behavior GO:0007625 6 5 0,000 0,02090874 0,10960007 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02090874 0,10936181 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02090874 0,10912458 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02090874 0,10888838 ! response to protozoan GO:0001562 10 5 0,000 0,02090874 0,1086532 ! lymph vessel development GO:0001945 10 5 0,000 0,02090874 0,10841903 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02090874 0,10818587 ! endochondral ossification GO:0001958 16 5 0,000 0,02090874 0,10795371 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02090874 0,10772255 ! anagen GO:0042640 6 5 0,000 0,02090874 0,10749237 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02090874 0,10726318 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02090874 0,10703496 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02090874 0,10680771 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02090874 0,10658142 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02090874 0,10635609 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02090874 0,10613171 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02090874 0,10590828 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02090874 0,10568578 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02090874 0,10546422 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02090874 0,10524358 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02090874 0,10502386 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02090874 0,10480506 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02090874 0,10458717 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02090874 0,10437019 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02090874 0,1041541 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02090874 0,10393891 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02090874 0,1037246 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02090874 0,10351117 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02090874 0,10329863 ! histidine catabolic process GO:0006548 6 5 0,000 0,02090874 0,10308695 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02090874 0,10287614 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02090874 0,10266619 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02090874 0,10245709 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02090874 0,10224884 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02090874 0,10204144 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02090874 0,10183488 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02090874 0,10162915 ! polyol catabolic process GO:0046174 7 5 0,000 0,02090874 0,10142426 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02090874 0,10122018 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02090874 0,10101693 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02090874 0,10081449 ! muscle cell migration GO:0014812 8 5 0,000 0,02090874 0,10061286 ! mitochondrial fission GO:0000266 8 5 0,000 0,02090874 0,10041204 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02090874 0,10021201 ! mRNA transcription GO:0009299 9 5 0,000 0,02090874 0,10001279 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02090874 0,09981435 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02090874 0,0996167 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02090874 0,09941982 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02090874 0,09922373 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02090874 0,09902841 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02090874 0,09883385 ! response to food GO:0032094 6 5 0,000 0,02090874 0,09864006 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02090874 0,09844703 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02090874 0,09825475 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02090874 0,09806322 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02090874 0,09787243 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02090874 0,09768239 ! forebrain neuron development GO:0021884 13 5 0,000 0,02090874 0,09749308 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02090874 0,09730451 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02090874 0,09711666 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02090874 0,09692954 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02090874 0,09674314 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02090874 0,09655745 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02090874 0,09637247 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02090874 0,0961882 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02090874 0,09600464 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02090874 0,09582177 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02090874 0,0956396 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02090874 0,09545812 ! basic amino acid transport GO:0015802 11 5 0,000 0,02090874 0,09527733 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02090874 0,09509722 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02090874 0,09491779 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02090874 0,09473904 ! depyrimidination GO:0045008 10 5 0,000 0,02090874 0,09456096 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02090874 0,09438355 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02090874 0,0942068 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02090874 0,09403071 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02090874 0,09385528 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02090874 0,0936805 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02090874 0,09350638 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02090874 0,0933329 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02090874 0,09316006 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02090874 0,09298786 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02090874 0,09281629 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02090874 0,09264536 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02090874 0,09247506 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02090874 0,09230538 ! response to arsenic GO:0046685 10 5 0,000 0,02090874 0,09213632 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02090874 0,09196788 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02090874 0,09180006 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02090874 0,09163284 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02090874 0,09146624 ! response to cadmium ion GO:0046686 7 5 0,000 0,02090874 0,09130024 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02090874 0,09113484 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02090874 0,09097004 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02090874 0,09080583 ! decidualization GO:0046697 11 5 0,000 0,02090874 0,09064222 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02090874 0,09047919 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02090874 0,09031675 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02090874 0,09015489 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02090874 0,08999362 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02090874 0,08983291 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02090874 0,08967278 ! neural tube patterning GO:0021532 7 5 0,000 0,02090874 0,08951322 ! embryonic cleavage GO:0040016 6 5 0,000 0,02090874 0,08935423 ! peroxisome fission GO:0016559 5 5 0,000 0,02090874 0,0891958 ! histone demethylation GO:0016577 10 5 0,000 0,02090874 0,08903793 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02090874 0,08888062 ! mitotic recombination GO:0006312 9 5 0,000 0,02090874 0,08872386 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02090874 0,08856766 ! metaphase plate congression GO:0051310 7 5 0,000 0,02090874 0,08841201 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02090874 0,0882569 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02090874 0,08810233 ! enteric nervous system development GO:0048484 8 5 0,000 0,02090874 0,08794831 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02090874 0,08779482 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02090874 0,08764187 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02090874 0,08748945 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02090874 0,08733755 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02090874 0,08718619 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02090874 0,08703535 ! plasminogen activation GO:0031639 5 5 0,000 0,02090874 0,08688503 ! B cell homeostasis GO:0001782 13 5 0,000 0,02090874 0,08673523 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02090874 0,08658594 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02090874 0,08643717 ! metaphase GO:0051323 8 5 0,000 0,02090874 0,0862889 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02090874 0,08614115 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02090874 0,0859939 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02090874 0,08584715 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02090874 0,0857009 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02090874 0,08555515 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02090874 0,0854099 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02090874 0,08526514 ! response to redox state GO:0051775 5 5 0,000 0,02090874 0,08512086 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02090874 0,08497708 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02090874 0,08483378 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02090874 0,08469096 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02090874 0,08454862 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02090874 0,08440676 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02090874 0,08426538 ! circadian behavior GO:0048512 13 5 0,000 0,02090874 0,08412447 ! striatum development GO:0021756 9 5 0,000 0,02090874 0,08398403 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02090874 0,08384405 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02090874 0,08370454 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02090874 0,0835655 ! glial cell migration GO:0008347 11 5 0,000 0,02090874 0,08342692 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02090874 0,08328879 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02090874 0,08315113 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02090874 0,08301391 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02090874 0,08287715 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02090874 0,08274084 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02090874 0,08260498 ! neuroprotection GO:0043526 6 5 0,000 0,02090874 0,08246956 ! neural plate development GO:0001840 8 5 0,000 0,02090874 0,08233458 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02090874 0,08220005 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02090874 0,08206596 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02090874 0,0819323 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02090874 0,08179907 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02090874 0,08166628 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02090874 0,08153392 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02090874 0,08140199 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02090874 0,08127049 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02090874 0,0811394 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02090874 0,08100875 ! spindle assembly GO:0051225 6 5 0,000 0,02090874 0,08087851 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02090874 0,08074869 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02090874 0,08061928 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02090874 0,08049029 ! drug metabolic process GO:0017144 6 5 0,000 0,02090874 0,08036171 ! stem cell division GO:0017145 11 5 0,000 0,02090874 0,08023354 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02090874 0,08010578 ! organ regeneration GO:0031100 7 5 0,000 0,02090874 0,07997843 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02090874 0,07985148 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02090874 0,07972493 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02090874 0,07959878 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,02113197 0,0803215 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,02188502 0,08305263 GO:0010863|positive regulation of phospholipase C activity, ! heterocycle catabolic process GO:0046700 85 54 1,000 0,02188502 0,08292184 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,0226491 0,08568198 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,0226491 0,08554747 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,0226491 0,08541338 ! aging GO:0007568 103 55 1,000 0,0226491 0,08527971 ! nuclear export GO:0051168 97 55 1,000 0,0226491 0,08514646 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,02342409 0,08792256 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,02342409 0,08778561 ! muscle fiber development GO:0048747 112 57 1,000 0,02420989 0,09058942 ! lipid modification GO:0030258 97 57 1,000 0,02420989 0,09044875 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,02420989 0,09030852 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,0250064 0,09313528 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02503814 0,09310939 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02503814 0,0929657 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02503814 0,09282246 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02503814 0,09267965 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02503814 0,09253729 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02503814 0,09239536 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02503814 0,09225387 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02503814 0,09211281 ! sleep GO:0030431 13 6 0,000 0,02503814 0,09197218 ! response to oxygen radical GO:0000305 11 6 0,000 0,02503814 0,09183197 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02503814 0,0916922 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,02503814 0,09155285 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02503814 0,09141392 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02503814 0,09127542 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02503814 0,09113733 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02503814 0,09099966 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02503814 0,09086241 ! forebrain regionalization GO:0021871 8 6 0,000 0,02503814 0,09072557 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02503814 0,09058914 ! male meiosis GO:0007140 7 6 0,000 0,02503814 0,09045312 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02503814 0,0903175 ! response to zinc ion GO:0010043 9 6 0,000 0,02503814 0,0901823 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,02503814 0,0900475 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02503814 0,0899131 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02503814 0,0897791 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02503814 0,0896455 ! malate metabolic process GO:0006108 11 6 0,000 0,02503814 0,0895123 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02503814 0,08937949 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02503814 0,08924707 ! protein refolding GO:0042026 15 6 0,000 0,02503814 0,08911505 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02503814 0,08898342 ! opsonization GO:0008228 8 6 0,000 0,02503814 0,08885218 ! mating behavior GO:0007617 7 6 0,000 0,02503814 0,08872132 ! neuron remodeling GO:0016322 15 6 0,000 0,02503814 0,08859085 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02503814 0,08846076 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02503814 0,08833105 ! equilibrioception GO:0050957 14 6 0,000 0,02503814 0,08820172 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02503814 0,08807277 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02503814 0,0879442 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02503814 0,087816 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02503814 0,08768817 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02503814 0,08756072 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02503814 0,08743364 ! toxin metabolic process GO:0009404 11 6 0,000 0,02503814 0,08730692 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02503814 0,08718057 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02503814 0,08705459 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02503814 0,08692897 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02503814 0,08680371 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,02503814 0,08667881 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02503814 0,08655427 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02503814 0,08643009 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02503814 0,08630627 ! thymic T cell selection GO:0045061 12 6 0,000 0,02503814 0,0861828 ! protein lipoylation GO:0009249 10 6 0,000 0,02503814 0,08605968 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02503814 0,08593691 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02503814 0,08581449 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02503814 0,08569243 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02503814 0,0855707 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02503814 0,08544933 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02503814 0,08532829 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02503814 0,0852076 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02503814 0,08508725 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02503814 0,08496724 ! hyperosmotic response GO:0006972 9 6 0,000 0,02503814 0,08484757 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02503814 0,08472824 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02503814 0,08460923 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02503814 0,08449057 ! urea metabolic process GO:0019627 7 6 0,000 0,02503814 0,08437223 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02503814 0,08425423 ! neutrophil activation GO:0042119 8 6 0,000 0,02503814 0,08413656 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02503814 0,08401921 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02503814 0,08390219 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02503814 0,0837855 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02503814 0,08366913 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02503814 0,08355309 ! neuron apoptosis GO:0051402 9 6 0,000 0,02503814 0,08343736 ! nucleoside salvage GO:0043174 9 6 0,000 0,02503814 0,08332196 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02503814 0,08320687 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02503814 0,0830921 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02503814 0,08297765 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02503814 0,08286351 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,02503814 0,08274969 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02503814 0,08263618 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02503814 0,08252298 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02503814 0,08241009 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02503814 0,08229751 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02503814 0,08218523 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02503814 0,08207326 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02503814 0,0819616 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02503814 0,08185024 ! establishment of spindle localization GO:0051293 12 6 0,000 0,02503814 0,08173918 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02503814 0,08162842 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02503814 0,08151796 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02503814 0,0814078 ! neural nucleus development GO:0048857 14 6 0,000 0,02503814 0,08129794 ! response to UV-C GO:0010225 11 6 0,000 0,02503814 0,08118838 ! astrocyte development GO:0014002 15 6 0,000 0,02503814 0,08107911 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02503814 0,08097013 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02503814 0,08086144 ! interaction with symbiont GO:0051702 13 6 0,000 0,02503814 0,08075305 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02503814 0,08064495 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02503814 0,08053713 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02503814 0,08042961 ! response to copper ion GO:0046688 10 6 0,000 0,02503814 0,08032237 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02503814 0,08021541 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02503814 0,08010874 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02503814 0,08000236 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02503814 0,07989625 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02503814 0,07979043 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02503814 0,07968489 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02503814 0,07957962 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02503814 0,07947464 ! hair follicle maturation GO:0048820 7 6 0,000 0,02503814 0,07936993 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02503814 0,07926549 ! Schwann cell development GO:0014044 15 6 0,000 0,02503814 0,07916133 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02503814 0,07905745 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02503814 0,07895383 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02503814 0,07885049 ! subpallium development GO:0021544 10 6 0,000 0,02503814 0,07874742 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02503814 0,07864462 ! histone ubiquitination GO:0016574 8 6 0,000 0,02503814 0,07854208 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02503814 0,07843981 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02503814 0,07833781 ! G2 phase GO:0051319 16 6 0,000 0,02503814 0,07823607 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02503814 0,0781346 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02503814 0,07803339 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02503814 0,07793244 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02503814 0,07783175 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02503814 0,07773132 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02503814 0,07763115 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02503814 0,07753124 ! receptor internalization GO:0031623 10 6 0,000 0,02503814 0,07743159 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,02503814 0,07733219 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02503814 0,07723305 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02503814 0,07713416 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02503814 0,07703552 ! protein deubiquitination GO:0016579 14 6 0,000 0,02503814 0,07693713 ! protein destabilization GO:0031648 9 6 0,000 0,02503814 0,076839 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02503814 0,07674111 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02503814 0,07664348 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02503814 0,07654609 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02503814 0,07644895 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02503814 0,07635206 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02503814 0,07625541 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02503814 0,07615901 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02503814 0,07606285 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02503814 0,07596693 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02503814 0,07587125 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02503814 0,07577582 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02503814 0,07568062 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02503814 0,07558567 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02503814 0,07549095 ! catecholamine transport GO:0051937 9 6 0,000 0,02503814 0,07539646 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02503814 0,07530222 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02503814 0,07520821 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02503814 0,07511443 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02503814 0,07502089 ! maternal placenta development GO:0001893 12 6 0,000 0,02503814 0,07492758 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02503814 0,0748345 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02503814 0,07474166 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02503814 0,07464904 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02503814 0,07455665 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02503814 0,07446449 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02503814 0,07437256 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02503814 0,07428086 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,02581351 0,07648682 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,02581351 0,07639274 ! camera-type eye development GO:0043010 116 60 1,000 0,02663112 0,07871556 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 0,02663112 0,07861898 ! viral reproductive process GO:0022415 126 62 1,000 0,02829744 0,08343582 ! tRNA transcription GO:0009304 14 7 0,000 0,02915027 0,08584522 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02915027 0,08574027 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02915027 0,08563559 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02915027 0,08553115 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,02915027 0,08542697 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02915027 0,08532305 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02915027 0,08521937 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02915027 0,08511595 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02915027 0,08501278 ! prostate gland development GO:0030850 13 7 0,000 0,02915027 0,08490986 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02915027 0,08480719 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02915027 0,08470476 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02915027 0,08460259 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02915027 0,08450066 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02915027 0,08439897 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02915027 0,08429753 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02915027 0,08419633 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,02915027 0,08409538 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02915027 0,08399466 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02915027 0,08389419 ! glycolipid transport GO:0046836 10 7 0,000 0,02915027 0,08379396 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02915027 0,08369397 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,02915027 0,08359421 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02915027 0,0834947 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02915027 0,08339542 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02915027 0,08329637 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02915027 0,08319756 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02915027 0,08309899 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02915027 0,08300064 ! mRNA stabilization GO:0048255 18 7 0,000 0,02915027 0,08290254 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02915027 0,08280466 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02915027 0,08270701 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02915027 0,08260959 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02915027 0,08251241 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02915027 0,08241545 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02915027 0,08231871 ! lipoprotein transport GO:0042953 14 7 0,000 0,02915027 0,08222221 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02915027 0,08212593 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02915027 0,08202988 ! rhythmic behavior GO:0007622 15 7 0,000 0,02915027 0,08193405 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02915027 0,08183844 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02915027 0,08174306 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02915027 0,0816479 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02915027 0,08155296 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02915027 0,08145824 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02915027 0,08136374 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02915027 0,08126946 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02915027 0,0811754 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02915027 0,08108155 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02915027 0,08098793 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02915027 0,08089452 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02915027 0,08080132 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02915027 0,08070834 ! spinal cord patterning GO:0021511 13 7 0,000 0,02915027 0,08061557 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02915027 0,08052301 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02915027 0,08043067 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02915027 0,08033854 ! adrenal gland development GO:0030325 17 7 0,000 0,02915027 0,08024662 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02915027 0,08015491 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02915027 0,08006341 ! ovulation GO:0030728 9 7 0,000 0,02915027 0,07997211 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02915027 0,07988103 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02915027 0,07979015 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02915027 0,07969948 ! microtubule nucleation GO:0007020 20 7 0,000 0,02915027 0,07960902 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02915027 0,07951876 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02915027 0,0794287 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02915027 0,07933885 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02915027 0,0792492 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02915027 0,07915976 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02915027 0,07907051 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02915027 0,07898147 ! galactose metabolic process GO:0006012 13 7 0,000 0,02915027 0,07889263 ! vesicle fusion GO:0006906 17 7 0,000 0,02915027 0,07880398 ! response to dietary excess GO:0002021 8 7 0,000 0,02915027 0,07871554 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02915027 0,07862729 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02915027 0,07853924 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02915027 0,07845139 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02915027 0,07836374 ! purine salvage GO:0043101 10 7 0,000 0,02915027 0,07827628 ! nucleoside transport GO:0015858 8 7 0,000 0,02915027 0,07818901 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02915027 0,07810194 ! parturition GO:0007567 14 7 0,000 0,02915027 0,07801507 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,02915027 0,07792838 ! rRNA modification GO:0000154 14 7 0,000 0,02915027 0,07784189 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02915027 0,07775559 ! spindle checkpoint GO:0031577 15 7 0,000 0,02915027 0,07766948 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02915027 0,07758357 ! macrophage differentiation GO:0030225 11 7 0,000 0,02915027 0,07749784 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02915027 0,0774123 ! centrosome duplication GO:0051298 13 7 0,000 0,02915027 0,07732695 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02915027 0,07724179 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02915027 0,07715681 ! fibrinolysis GO:0042730 10 7 0,000 0,02915027 0,07707203 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02915027 0,07698743 ! eating behavior GO:0042755 7 7 0,000 0,02915027 0,07690301 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02915027 0,07681878 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02915027 0,07673473 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02915027 0,07665087 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02915027 0,07656719 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02915027 0,07648369 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02915027 0,07640038 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02915027 0,07631724 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02915027 0,07623429 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02915027 0,07615151 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02915027 0,07606892 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02915027 0,07598651 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02915027 0,07590427 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02915027 0,07582221 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02915027 0,07574033 ! regulation of meiosis GO:0040020 12 7 0,000 0,02915027 0,07565862 GO:0051445|regulation of meiotic cell cycle, ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02915027 0,0755771 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02915027 0,07549574 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02915027 0,07541456 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02915027 0,07533356 ! anaphase GO:0051322 17 7 0,000 0,02915027 0,07525273 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02915027 0,07517207 ! axonal fasciculation GO:0007413 18 7 0,000 0,02915027 0,07509159 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02915027 0,07501128 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02915027 0,07493114 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02915027 0,07485117 ! diuresis GO:0030146 12 7 0,000 0,02915027 0,07477137 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02915027 0,07469174 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02915027 0,07461228 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02915027 0,07453299 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02915027 0,07445387 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02915027 0,07437491 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02915027 0,07429613 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02915027 0,07421751 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02915027 0,07413905 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02915027 0,07406077 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02915027 0,07398264 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02915027 0,07390468 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02915027 0,07382689 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02915027 0,07374926 ! lymph node development GO:0048535 10 7 0,000 0,02915027 0,07367179 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02915027 0,07359449 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02915027 0,07351734 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02915027 0,07344036 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02915027 0,07336354 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02915027 0,07328688 ! adult feeding behavior GO:0008343 9 7 0,000 0,02915027 0,07321038 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02915027 0,07313404 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02915027 0,07305786 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02915027 0,07298184 ! muscle adaptation GO:0043500 14 7 0,000 0,02915027 0,07290597 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02915027 0,07283026 ! retina homeostasis GO:0001895 12 7 0,000 0,02915027 0,07275471 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02915027 0,07267932 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02915027 0,07260408 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02915027 0,072529 ! protein prenylation GO:0018342 18 7 0,000 0,02915027 0,07245408 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02915027 0,0723793 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02915027 0,07230469 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02915027 0,07223022 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,03087316 0,07642061 GO:0035113|embryonic appendage morphogenesis, ! extracellular matrix organization GO:0030198 133 66 1,000 0,03175167 0,07851442 ! secondary metabolic process GO:0019748 116 66 1,000 0,03175167 0,07843381 ! cell projection assembly GO:0030031 120 66 1,000 0,03175167 0,07835336 ! cellular hormone metabolic process GO:0034754 113 67 1,000 0,03263999 0,08046293 ! activation of immune response GO:0002253 105 67 1,000 0,03263999 0,08038057 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03324518 0,08178723 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03324518 0,08170369 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,03324518 0,08162032 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,03324518 0,08153712 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,03324518 0,08145409 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03324518 0,08137122 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03324518 0,08128853 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,03324518 0,081206 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,03324518 0,08112364 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,03324518 0,08104145 ! meiotic prophase I GO:0007128 13 8 0,000 0,03324518 0,08095943 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03324518 0,08087757 ! oligopeptide transport GO:0006857 15 8 0,000 0,03324518 0,08079587 ! UTP metabolic process GO:0046051 8 8 0,000 0,03324518 0,08071434 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03324518 0,08063298 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03324518 0,08055177 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03324518 0,08047074 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03324518 0,08038986 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03324518 0,08030915 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03324518 0,0802286 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03324518 0,08014821 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03324518 0,08006798 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,03324518 0,07998791 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03324518 0,079908 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03324518 0,07982826 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03324518 0,07974867 ! reflex GO:0060004 16 8 0,000 0,03324518 0,07966924 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,03324518 0,07958996 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03324518 0,07951085 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03324518 0,07943189 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03324518 0,07935309 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,03324518 0,07927444 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,03324518 0,07919595 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03324518 0,07911762 ! pigment granule organization GO:0048753 16 8 0,000 0,03324518 0,07903944 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03324518 0,07896141 ! astrocyte differentiation GO:0048708 18 8 0,000 0,03324518 0,07888354 ! histidine metabolic process GO:0006547 16 8 0,000 0,03324518 0,07880582 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03324518 0,07872826 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03324518 0,07865085 ! glycine catabolic process GO:0006546 13 8 0,000 0,03324518 0,07857359 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03324518 0,07849648 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,03324518 0,07841952 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,03324518 0,07834272 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,03324518 0,07826606 ! melanin metabolic process GO:0006582 15 8 0,000 0,03324518 0,07818955 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03324518 0,0781132 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03324518 0,07803699 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03324518 0,07796093 ! macrophage activation GO:0042116 12 8 0,000 0,03324518 0,07788502 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03324518 0,07780925 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03324518 0,07773364 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03324518 0,07765817 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,03324518 0,07758284 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,03324518 0,07750767 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03324518 0,07743264 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,03324518 0,07735775 ! osteoblast development GO:0002076 16 8 0,000 0,03324518 0,07728301 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,03324518 0,07720841 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,03324518 0,07713396 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03324518 0,07705965 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,03324518 0,07698548 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03324518 0,07691145 ! response to UV-B GO:0010224 16 8 0,000 0,03324518 0,07683757 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03324518 0,07676383 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03324518 0,07669023 ! intermediate filament organization GO:0045109 12 8 0,000 0,03324518 0,07661677 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03324518 0,07654346 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,03324518 0,07647028 ! cellular extravasation GO:0045123 12 8 0,000 0,03324518 0,07639724 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03324518 0,07632434 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03324518 0,07625158 ! response to antibiotic GO:0046677 11 8 0,000 0,03324518 0,07617896 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03324518 0,07610648 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,03324518 0,07603414 ! DNA topological change GO:0006265 12 8 0,000 0,03324518 0,07596193 ! response to tropane GO:0014073 15 8 0,000 0,03324518 0,07588986 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,03324518 0,07581793 ! melanosome transport GO:0032402 13 8 0,000 0,03324518 0,07574613 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,03324518 0,07567447 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03324518 0,07560294 ! mast cell activation GO:0045576 14 8 0,000 0,03324518 0,07553155 ! multicellular organismal aging GO:0010259 18 8 0,000 0,03324518 0,07546029 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,03324518 0,07538917 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,03324518 0,07531818 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,03324518 0,07524733 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03324518 0,07517661 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03324518 0,07510602 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,03324518 0,07503556 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03324518 0,07496524 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03324518 0,07489505 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03324518 0,07482499 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03324518 0,07475506 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03324518 0,07468526 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03324518 0,07461559 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03324518 0,07454605 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,03324518 0,07447664 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03324518 0,07440736 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03324518 0,07433821 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03324518 0,07426918 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03324518 0,07420029 ! hormone catabolic process GO:0042447 17 8 0,000 0,03324518 0,07413152 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03324518 0,07406288 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,03324518 0,07399437 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,03324518 0,07392598 ! ATP catabolic process GO:0006200 11 8 0,000 0,03324518 0,07385772 ! blastocyst growth GO:0001832 19 8 0,000 0,03324518 0,07378959 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03324518 0,07372158 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03324518 0,07365369 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03324518 0,07358594 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03324518 0,0735183 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03324518 0,07345079 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,03324518 0,07338341 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,03324518 0,07331614 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03324518 0,073249 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03324518 0,07318199 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03324518 0,07311509 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,03324518 0,07304832 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,03324518 0,07298167 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03324518 0,07291514 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03324518 0,07284874 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03324518 0,07278245 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03324518 0,07271628 ! viral reproduction GO:0016032 134 68 1,000 0,03353802 0,07329016 ! regulation of lipase activity GO:0060191 130 68 1,000 0,03353802 0,07322365 ! appendage morphogenesis GO:0035107 135 70 1,000 0,03536281 0,07713773 GO:0035108|limb morphogenesis, ! reproductive structure development GO:0048608 113 71 1,000 0,03628938 0,07908718 ! appendage development GO:0048736 136 71 1,000 0,03628938 0,07901561 GO:0060173|limb development, ! B cell activation GO:0042113 160 71 1,000 0,03628938 0,07894417 ! regulation of immune effector process GO:0002697 137 71 1,000 0,03628938 0,07887286 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,03722528 0,08083396 ! axon extension GO:0048675 15 9 0,000 0,03732296 0,08097299 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,03732296 0,08090004 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,03732296 0,08082723 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,03732296 0,08075454 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03732296 0,08068199 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,03732296 0,08060956 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,03732296 0,08053726 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,03732296 0,0804651 ! phosphate transport GO:0006817 19 9 0,000 0,03732296 0,08039306 ! reproductive behavior GO:0019098 19 9 0,000 0,03732296 0,08032115 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03732296 0,08024937 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,03732296 0,08017772 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03732296 0,0801062 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,03732296 0,0800348 ! GTP metabolic process GO:0046039 9 9 0,000 0,03732296 0,07996353 ! RNA methylation GO:0001510 15 9 0,000 0,03732296 0,07989239 ! elastic fiber assembly GO:0048251 15 9 0,000 0,03732296 0,07982138 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,03732296 0,07975049 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,03732296 0,07967972 ! regulation of histone modification GO:0031056 12 9 0,000 0,03732296 0,07960909 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,03732296 0,07953857 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,03732296 0,07946819 ! chemosensory behavior GO:0007635 20 9 0,000 0,03732296 0,07939792 ! microtubule bundle formation GO:0001578 21 9 0,000 0,03732296 0,07932778 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,03732296 0,07925777 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,03732296 0,07918787 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03732296 0,07911811 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,03732296 0,07904846 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,03732296 0,07897894 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,03732296 0,07890953 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03732296 0,07884025 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03732296 0,0787711 ! protein targeting to ER GO:0045047 22 9 0,000 0,03732296 0,07870206 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,03732296 0,07863314 ! T cell selection GO:0045058 23 9 0,000 0,03732296 0,07856435 ! endosome organization GO:0007032 17 9 0,000 0,03732296 0,07849567 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03732296 0,07842712 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03732296 0,07835868 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03732296 0,07829037 ! mannose metabolic process GO:0006013 13 9 0,000 0,03732296 0,07822217 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,03732296 0,07815409 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,03732296 0,07808613 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,03732296 0,07801829 ! receptor clustering GO:0043113 18 9 0,000 0,03732296 0,07795056 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,03732296 0,07788296 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03732296 0,07781547 ! ruffle organization GO:0031529 15 9 0,000 0,03732296 0,07774809 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,03732296 0,07768084 ! behavioral fear response GO:0001662 22 9 0,000 0,03732296 0,0776137 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,03732296 0,07754667 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,03732296 0,07747977 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,03732296 0,07741297 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,03732296 0,0773463 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,03732296 0,07727973 ! segment specification GO:0007379 13 9 0,000 0,03732296 0,07721328 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03732296 0,07714695 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,03732296 0,07708073 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03732296 0,07701462 ! response to amine stimulus GO:0014075 13 9 0,000 0,03732296 0,07694863 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03732296 0,07688275 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,03732296 0,07681698 ! erythrocyte development GO:0048821 15 9 0,000 0,03732296 0,07675132 ! gas homeostasis GO:0033483 16 9 0,000 0,03732296 0,07668578 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03732296 0,07662035 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,03732296 0,07655503 ! renal water homeostasis GO:0003091 14 9 0,000 0,03732296 0,07648982 ! postreplication repair GO:0006301 22 9 0,000 0,03732296 0,07642472 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,03732296 0,07635974 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,03732296 0,07629486 ! icosanoid secretion GO:0032309 15 9 0,000 0,03732296 0,07623009 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,03732296 0,07616544 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03732296 0,07610089 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,03732296 0,07603645 ! regulation of cell division GO:0051302 15 9 0,000 0,03732296 0,07597212 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,03732296 0,0759079 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,03732296 0,07584379 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03732296 0,07577979 ! sterol catabolic process GO:0016127 11 9 0,000 0,03732296 0,07571589 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03732296 0,07565211 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,03732296 0,07558843 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,03732296 0,07552485 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,03732296 0,07546139 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,03732296 0,07539803 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,03732296 0,07533477 ! musculoskeletal movement GO:0050881 14 9 0,000 0,03732296 0,07527163 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,03732296 0,07520858 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,03732296 0,07514565 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03732296 0,07508282 ! purine base metabolic process GO:0006144 21 9 0,000 0,03732296 0,07502009 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,03732296 0,07495747 ! pigment granule transport GO:0051904 17 9 0,000 0,03732296 0,07489495 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,03732296 0,07483254 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,03732296 0,07477023 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,03732296 0,07470803 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03732296 0,07464593 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03732296 0,07458393 ! mitochondrion localization GO:0051646 15 9 0,000 0,03732296 0,07452203 ! axon guidance GO:0007411 139 73 1,000 0,03817042 0,07615093 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,03912469 0,07799006 GO:0090046|regulation of transcription regulator activity, ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,04008801 0,07984417 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,04008801 0,07977813 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,04106029 0,0816455 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,04138368 0,08222058 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04138368 0,08215275 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,04138368 0,08208502 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04138368 0,0820174 ! synapsis GO:0007129 13 10 0,000 0,04138368 0,0819499 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,04138368 0,08188251 ! N-glycan processing GO:0006491 20 10 0,000 0,04138368 0,08181522 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,04138368 0,08174805 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04138368 0,08168099 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,04138368 0,08161404 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,04138368 0,0815472 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,04138368 0,08148046 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,04138368 0,08141384 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,04138368 0,08134733 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,04138368 0,08128092 ! androgen metabolic process GO:0008209 17 10 0,000 0,04138368 0,08121462 ! phospholipid efflux GO:0033700 16 10 0,000 0,04138368 0,08114843 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04138368 0,08108235 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,04138368 0,08101638 ! lung alveolus development GO:0048286 26 10 0,000 0,04138368 0,08095051 ! pathogenesis GO:0009405 13 10 0,000 0,04138368 0,08088475 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04138368 0,0808191 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,04138368 0,08075355 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,04138368 0,08068811 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,04138368 0,08062278 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,04138368 0,08055755 ! endoderm development GO:0007492 16 10 0,000 0,04138368 0,08049242 ! arginine catabolic process GO:0006527 13 10 0,000 0,04138368 0,08042741 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04138368 0,08036249 ! proline metabolic process GO:0006560 13 10 0,000 0,04138368 0,08029768 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04138368 0,08023298 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,04138368 0,08016838 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,04138368 0,08010388 ! V(D)J recombination GO:0033151 28 10 0,000 0,04138368 0,08003949 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04138368 0,0799752 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,04138368 0,07991102 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,04138368 0,07984694 ! B cell proliferation GO:0042100 18 10 0,000 0,04138368 0,07978296 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,04138368 0,07971908 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,04138368 0,0796553 ! multicellular organism growth GO:0035264 18 10 0,000 0,04138368 0,07959163 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,04138368 0,07952806 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,04138368 0,07946459 ! epithelial cell development GO:0002064 20 10 0,000 0,04138368 0,07940122 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,04138368 0,07933795 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04138368 0,07927478 ! macroautophagy GO:0016236 17 10 0,000 0,04138368 0,07921172 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,04138368 0,07914875 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,04138368 0,07908588 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,04138368 0,07902312 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,04138368 0,07896045 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04138368 0,07889788 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04138368 0,07883541 ! brain morphogenesis GO:0048854 23 10 0,000 0,04138368 0,07877304 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,04138368 0,07871077 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,04138368 0,0786486 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,04138368 0,07858653 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,04138368 0,07852455 ! blastoderm segmentation GO:0007350 18 10 0,000 0,04138368 0,07846267 ! response to dsRNA GO:0043331 20 10 0,000 0,04138368 0,07840089 ! DNA ligation GO:0006266 19 10 0,000 0,04138368 0,0783392 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04138368 0,07827762 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04138368 0,07821613 ! melanosome localization GO:0032400 16 10 0,000 0,04138368 0,07815473 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,04138368 0,07809343 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,04138368 0,07803223 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04138368 0,07797113 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,04138368 0,07791012 ! mRNA cleavage GO:0006379 17 10 0,000 0,04138368 0,0778492 ! protein sumoylation GO:0016925 15 10 0,000 0,04138368 0,07778838 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04138368 0,07772766 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04138368 0,07766703 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,04138368 0,07760649 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,04138368 0,07754605 ! salivary gland development GO:0007431 27 10 0,000 0,04138368 0,0774857 ! prophase GO:0051324 15 10 0,000 0,04138368 0,07742545 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04138368 0,07736529 ! apical protein localization GO:0045176 15 10 0,000 0,04138368 0,07730522 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,04138368 0,07724525 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,04138368 0,07718537 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,04138368 0,07712558 ! midbrain development GO:0030901 13 10 0,000 0,04138368 0,07706589 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04138368 0,07700629 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,04138368 0,07694678 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,04138368 0,07688736 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,04138368 0,07682803 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04138368 0,0767688 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,04138368 0,07670965 ! detection of calcium ion GO:0005513 23 10 0,000 0,04138368 0,0766506 ! oocyte development GO:0048599 17 10 0,000 0,04138368 0,07659164 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04138368 0,07653277 ! blastocyst formation GO:0001825 17 10 0,000 0,04138368 0,07647398 ! cerebellar cortex development GO:0021695 15 10 0,000 0,04138368 0,07641529 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,04138368 0,07635669 ! activation of innate immune response GO:0002218 12 10 0,000 0,04138368 0,07629818 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,04138368 0,07623976 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,04138368 0,07618143 ! response to nicotine GO:0035094 20 10 0,000 0,04138368 0,07612319 ! establishment of cell polarity GO:0030010 16 10 0,000 0,04138368 0,07606503 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,04138368 0,07600697 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04138368 0,07594899 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,04204143 0,07709732 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,04303135 0,07885257 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,04402995 0,08062104 ! inorganic anion transport GO:0015698 138 80 1,000 0,04503714 0,08240255 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,0454274 0,08305343 ! respiratory burst GO:0045730 17 11 0,000 0,0454274 0,08299037 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,0454274 0,0829274 ! neuron fate specification GO:0048665 17 11 0,000 0,0454274 0,08286453 ! telencephalon cell migration GO:0022029 20 11 0,000 0,0454274 0,08280176 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,0454274 0,08273907 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,0454274 0,08267649 ! thyroid gland development GO:0030878 26 11 0,000 0,0454274 0,082614 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,0454274 0,0825516 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,0454274 0,0824893 ! response to pain GO:0048265 24 11 0,000 0,0454274 0,08242709 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,0454274 0,08236497 ! T cell proliferation GO:0042098 26 11 0,000 0,0454274 0,08230295 ! blood vessel remodeling GO:0001974 29 11 0,000 0,0454274 0,08224102 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,0454274 0,08217919 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,0454274 0,08211744 ! bone resorption GO:0045453 16 11 0,000 0,0454274 0,08205579 ! ventral spinal cord development GO:0021517 21 11 0,000 0,0454274 0,08199424 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0454274 0,08193277 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,0454274 0,0818714 ! melanocyte differentiation GO:0030318 21 11 0,000 0,0454274 0,08181012 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,0454274 0,08174893 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,0454274 0,08168783 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,0454274 0,08162682 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,0454274 0,08156591 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,0454274 0,08150508 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,0454274 0,08144435 ! UV protection GO:0009650 19 11 0,000 0,0454274 0,08138371 ! adult heart development GO:0007512 14 11 0,000 0,0454274 0,08132315 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,0454274 0,08126269 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0454274 0,08120232 ! temperature homeostasis GO:0001659 17 11 0,000 0,0454274 0,08114203 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,0454274 0,08108184 ! negative regulation of ossification GO:0030279 26 11 0,000 0,0454274 0,08102173 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,0454274 0,08096172 ! regulation of organ growth GO:0046620 13 11 0,000 0,0454274 0,08090179 ! pigment granule localization GO:0051875 20 11 0,000 0,0454274 0,08084195 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,0454274 0,0807822 ! vasoconstriction GO:0042310 18 11 0,000 0,0454274 0,08072254 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0454274 0,08066297 ! embryonic axis specification GO:0000578 18 11 0,000 0,0454274 0,08060348 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,0454274 0,08054408 ! snRNA metabolic process GO:0016073 24 11 0,000 0,0454274 0,08048477 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0454274 0,08042555 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,0454274 0,08036641 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,0454274 0,08030736 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,0454274 0,0802484 ! zymogen activation GO:0031638 15 11 0,000 0,0454274 0,08018952 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,0454274 0,08013073 ! neuroblast proliferation GO:0007405 24 11 0,000 0,0454274 0,08007203 ! nucleosome positioning GO:0016584 15 11 0,000 0,0454274 0,08001341 ! regulation of isotype switching GO:0045191 22 11 0,000 0,0454274 0,07995488 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,0454274 0,07989643 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,0454274 0,07983807 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,0454274 0,07977979 ! acid secretion GO:0046717 18 11 0,000 0,0454274 0,0797216 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0454274 0,0796635 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,0454274 0,07960548 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,0454274 0,07954754 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,0454274 0,07948969 ! oocyte differentiation GO:0009994 18 11 0,000 0,0454274 0,07943192 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,0454274 0,07937423 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,0454274 0,07931663 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,0454274 0,07925911 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0454274 0,07920168 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,0454274 0,07914433 GO:0010829|negative regulation of glucose transport, ! embryonic gut development GO:0048566 15 11 0,000 0,0454274 0,07908706 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,0454274 0,07902988 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,0454274 0,07897277 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,0454274 0,07891575 ! defense response to fungus GO:0050832 13 11 0,000 0,0454274 0,07885882 ! developmental induction GO:0031128 19 11 0,000 0,0454274 0,07880196 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,0454274 0,07874519 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0454274 0,07868849 ! sequestering of metal ion GO:0051238 14 11 0,000 0,0454274 0,07863188 ! lamellipodium assembly GO:0030032 20 11 0,000 0,0454274 0,07857535 ! nucleus localization GO:0051647 19 11 0,000 0,0454274 0,07851891 ! regulation of synapse organization GO:0050807 17 11 0,000 0,0454274 0,07846254 ! T cell activation GO:0042110 168 81 1,000 0,04605283 0,07948574 ! response to hypoxia GO:0001666 171 81 1,000 0,04605283 0,07942876 ! digestion GO:0007586 112 81 1,000 0,04605283 0,07937186 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,04605283 0,07931505 ! response to drug GO:0042493 143 82 1,000 0,04707695 0,08102084 ! response to oxygen levels GO:0070482 176 83 1,000 0,04810939 0,08273852 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,04915007 0,08446791 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,04945419 0,0849299 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,04945419 0,08486932 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,04945419 0,08480883 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,04945419 0,08474843 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,04945419 0,08468811 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,04945419 0,08462787 ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,04945419 0,08456773 ! hippocampus development GO:0021766 26 12 0,000 0,04945419 0,08450766 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,04945419 0,08444769 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,04945419 0,08438779 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,04945419 0,08432799 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,04945419 0,08426826 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,04945419 0,08420863 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,04945419 0,08414907 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,04945419 0,0840896 ! drug transport GO:0015893 16 12 0,000 0,04945419 0,08403022 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,04945419 0,08397092 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,04945419 0,0839117 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,04945419 0,08385256 ! polyamine metabolic process GO:0006595 17 12 0,000 0,04945419 0,08379351 ! focal adhesion formation GO:0048041 35 12 0,000 0,04945419 0,08373455 ! mitotic spindle organization GO:0007052 21 12 0,000 0,04945419 0,08367566 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,04945419 0,08361686 ! forebrain cell migration GO:0021885 21 12 0,000 0,04945419 0,08355814 ! asymmetric protein localization GO:0008105 20 12 0,000 0,04945419 0,0834995 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,04945419 0,08344095 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,04945419 0,08338247 ! entry into host cell GO:0030260 32 12 0,000 0,04945419 0,08332408 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,04945419 0,08326577 ! monoamine transport GO:0015844 18 12 0,000 0,04945419 0,08320754 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04945419 0,0831494 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,04945419 0,08309133 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,04945419 0,08303335 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,04945419 0,08297545 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,04945419 0,08291762 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,04945419 0,08285988 ! protein homotetramerization GO:0051289 21 12 0,000 0,04945419 0,08280222 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,04945419 0,08274464 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,04945419 0,08268714 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04945419 0,08262971 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,04945419 0,08257237 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,04945419 0,08251511 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,04945419 0,08245793 ! cranial nerve development GO:0021545 20 12 0,000 0,04945419 0,08240082 ! fucose catabolic process GO:0019317 22 12 0,000 0,04945419 0,0823438 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,04945419 0,08228685 ! histone methylation GO:0016571 26 12 0,000 0,04945419 0,08222999 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,04945419 0,0821732 ! autonomic nervous system development GO:0048483 24 12 0,000 0,04945419 0,08211649 ! gland morphogenesis GO:0022612 29 12 0,000 0,04945419 0,08205985 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,04945419 0,0820033 ! T cell homeostasis GO:0043029 25 12 0,000 0,04945419 0,08194682 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,04945419 0,08189043 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,04945419 0,08183411 ! spleen development GO:0048536 22 12 0,000 0,04945419 0,08177786 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,04945419 0,0817217 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,04945419 0,08166561 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,04945419 0,08160959 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,04945419 0,08155366 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,04945419 0,0814978 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,04945419 0,08144202 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,04945419 0,08138631 ! response to cold GO:0009409 17 12 0,000 0,04945419 0,08133068 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,04945419 0,08127513 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,04945419 0,08121965 ! response to unfolded protein GO:0006986 131 85 1,000 0,05019891 0,08238648 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,05019891 0,08233032 GO:0002696|positive regulation of leukocyte activation, ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,05232071 0,08575178 ! regulation of DNA binding GO:0051101 155 88 1,000 0,05339349 0,08745047 ! regulation of neurological system process GO:0031644 148 88 1,000 0,05339349 0,08739098 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05346414 0,08744712 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,05346414 0,08738771 ! regulation of chemokine production GO:0032642 18 13 0,000 0,05346414 0,08732838 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05346414 0,08726914 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,05346414 0,08720997 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,05346414 0,08715089 ! lipid localization GO:0010876 28 13 0,000 0,05346414 0,08709188 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,05346414 0,08703296 ! organelle fusion GO:0048284 32 13 0,000 0,05346414 0,08697411 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,05346414 0,08691535 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,05346414 0,08685666 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,05346414 0,08679805 ! endocrine pancreas development GO:0031018 22 13 0,000 0,05346414 0,08673952 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,05346414 0,08668107 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,05346414 0,0866227 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,05346414 0,08656441 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05346414 0,08650619 ! methionine metabolic process GO:0006555 27 13 0,000 0,05346414 0,08644806 ! plasma membrane organization GO:0007009 24 13 0,000 0,05346414 0,08639 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,05346414 0,08633202 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,05346414 0,08627412 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,05346414 0,08621629 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,05346414 0,08615855 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,05346414 0,08610088 ! cytokine metabolic process GO:0042107 22 13 0,000 0,05346414 0,08604328 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,05346414 0,08598577 ! exocrine system development GO:0035272 32 13 0,000 0,05346414 0,08592833 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,05346414 0,08587097 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,05346414 0,08581368 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,05346414 0,08575647 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,05346414 0,08569934 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,05346414 0,08564228 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,05346414 0,0855853 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,05346414 0,0855284 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,05346414 0,08547157 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05346414 0,08541481 ! ribosome assembly GO:0042255 17 13 0,000 0,05346414 0,08535814 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,05346414 0,08530153 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,05346414 0,085245 ! chromatin silencing GO:0006342 26 13 0,000 0,05346414 0,08518855 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,05346414 0,08513217 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05346414 0,08507587 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05346414 0,08501964 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,05346414 0,08496348 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,05346414 0,0849074 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,05346414 0,08485139 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05346414 0,08479546 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,05346414 0,0847396 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,05346414 0,08468381 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,05346414 0,0846281 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,05346414 0,08457246 ! embryonic placenta development GO:0001892 23 13 0,000 0,05346414 0,08451689 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,05346414 0,0844614 ! insulin secretion GO:0030073 23 13 0,000 0,05346414 0,08440598 ! actin filament polymerization GO:0030041 24 13 0,000 0,05346414 0,08435063 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,05346414 0,08429535 ! acrosome reaction GO:0007340 18 13 0,000 0,05346414 0,08424015 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,05447409 0,08577531 ! sex differentiation GO:0007548 145 90 1,000 0,05556243 0,08743178 ! response to protein stimulus GO:0051789 149 91 1,000 0,05665841 0,08909812 ! rRNA transcription GO:0009303 25 14 0,000 0,05745729 0,0902954 ! lactation GO:0007595 26 14 0,000 0,05745729 0,09023646 ! reproductive cellular process GO:0048610 20 14 0,000 0,05745729 0,09017759 ! tRNA modification GO:0006400 20 14 0,000 0,05745729 0,09011881 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,05745729 0,0900601 ! regulation of S phase GO:0033261 23 14 0,000 0,05745729 0,09000147 ! water transport GO:0006833 21 14 0,000 0,05745729 0,08994291 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,05745729 0,08988443 ! non-recombinational repair GO:0000726 25 14 0,000 0,05745729 0,08982602 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,05745729 0,0897677 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,05745729 0,08970944 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,05745729 0,08965127 ! RNA polyadenylation GO:0043631 30 14 0,000 0,05745729 0,08959316 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,05745729 0,08953514 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,05745729 0,08947719 ! regulated secretory pathway GO:0045055 23 14 0,000 0,05745729 0,08941931 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,05745729 0,08936151 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,05745729 0,08930378 ! arginine metabolic process GO:0006525 17 14 0,000 0,05745729 0,08924613 ! regulation of heart rate GO:0002027 24 14 0,000 0,05745729 0,08918855 ! organic alcohol transport GO:0015850 29 14 0,000 0,05745729 0,08913105 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,05745729 0,08907362 ! embryo implantation GO:0007566 30 14 0,000 0,05745729 0,08901626 ! neutral amino acid transport GO:0015804 26 14 0,000 0,05745729 0,08895898 ! L-amino acid transport GO:0015807 30 14 0,000 0,05745729 0,08890177 ! bone mineralization GO:0030282 17 14 0,000 0,05745729 0,08884463 ! stem cell development GO:0048864 43 14 0,000 0,05745729 0,08878757 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,05745729 0,08873058 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,05745729 0,08867367 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,05745729 0,08861683 ! cerebellum development GO:0021549 21 14 0,000 0,05745729 0,08856006 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,05745729 0,08850336 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,05745729 0,08844674 ! cofactor transport GO:0051181 26 14 0,000 0,05745729 0,08839019 ! NADP metabolic process GO:0006739 24 14 0,000 0,05745729 0,08833371 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,05745729 0,0882773 ! intestinal absorption GO:0050892 25 14 0,000 0,05745729 0,08822096 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,05745729 0,0881647 ! oxygen transport GO:0015671 21 14 0,000 0,05745729 0,08810851 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,05745729 0,08805239 ! male genitalia development GO:0030539 24 14 0,000 0,05745729 0,08799634 ! regulation of RNA stability GO:0043487 32 14 0,000 0,05745729 0,08794036 ! regulation of axon extension GO:0030516 37 14 0,000 0,05745729 0,08788446 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,05745729 0,08782862 ! regulation of defense response GO:0031347 149 92 1,000 0,05776195 0,08823825 ! vitamin metabolic process GO:0006766 139 92 1,000 0,05776195 0,08818226 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,05887297 0,08982142 ! regulation of membrane potential GO:0042391 164 93 1,000 0,05887297 0,0897645 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,05887297 0,08970765 ! female pregnancy GO:0007565 164 94 1,000 0,0599914 0,09135399 ! transcription initiation GO:0006352 153 94 1,000 0,0599914 0,09129621 ! regulation of T cell activation GO:0050863 158 94 1,000 0,0599914 0,0912385 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,06143374 0,09337307 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06143374 0,09331413 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,06143374 0,09325525 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,06143374 0,09319645 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,06143374 0,09313773 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,06143374 0,09307908 ! copper ion transport GO:0006825 20 15 0,000 0,06143374 0,0930205 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,06143374 0,092962 ! sulfate transport GO:0008272 23 15 0,000 0,06143374 0,09290357 ! response to cAMP GO:0051591 22 15 0,000 0,06143374 0,09284521 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,06143374 0,09278693 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,06143374 0,09272872 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,06143374 0,09267058 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,06143374 0,09261252 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,06143374 0,09255453 ! response to hexose stimulus GO:0009746 22 15 0,000 0,06143374 0,09249661 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,06143374 0,09243876 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,06143374 0,09238099 ! pituitary gland development GO:0021983 29 15 0,000 0,06143374 0,09232328 ! vesicle coating GO:0006901 33 15 0,000 0,06143374 0,09226565 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,06143374 0,0922081 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,06143374 0,09215061 ! regulation of exocytosis GO:0017157 22 15 0,000 0,06143374 0,09209319 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,06143374 0,09203585 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,06143374 0,09197858 ! regulation of vasodilation GO:0042312 26 15 0,000 0,06143374 0,09192138 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,06143374 0,09186425 ! histone deacetylation GO:0016575 20 15 0,000 0,06143374 0,09180719 ! mRNA splice site selection GO:0006376 38 15 0,000 0,06143374 0,0917502 ! tissue regeneration GO:0042246 26 15 0,000 0,06143374 0,09169329 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,06143374 0,09163644 ! water homeostasis GO:0030104 27 15 0,000 0,06143374 0,09157966 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,06143374 0,09152296 ! muscle maintenance GO:0046716 26 15 0,000 0,06143374 0,09146632 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,06143374 0,09140976 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,06143374 0,09135326 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,06143374 0,09129684 ! dopamine metabolic process GO:0042417 35 15 0,000 0,06143374 0,09124048 ! heme biosynthetic process GO:0006783 29 15 0,000 0,06143374 0,09118419 ! cell killing GO:0001906 29 15 0,000 0,06143374 0,09112798 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,06143374 0,09107183 ! detection of bacterium GO:0016045 18 15 0,000 0,06143374 0,09101575 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,06143374 0,09095974 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,06143374 0,0909038 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,06143374 0,09084793 ! peptide hormone processing GO:0016486 23 15 0,000 0,06143374 0,09079212 ! leukocyte differentiation GO:0002521 202 96 1,000 0,06225013 0,09194218 ! positive regulation of immune response GO:0050778 156 96 1,000 0,06225013 0,09188577 ! protein ubiquitination GO:0016567 217 97 1,000 0,06339027 0,09351134 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,06539354 0,09640739 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,06539354 0,09634835 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,06539354 0,09628939 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,06539354 0,09623049 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,06539354 0,09617167 ! bone remodeling GO:0046849 27 16 0,000 0,06539354 0,09611292 ! filopodium assembly GO:0046847 32 16 0,000 0,06539354 0,09605425 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,06539354 0,09599564 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,06539354 0,09593711 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,06539354 0,09587865 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,06539354 0,09582025 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,06539354 0,09576193 ! startle response GO:0001964 28 16 0,000 0,06539354 0,09570368 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,06539354 0,09564551 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,06539354 0,0955874 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,06539354 0,09552936 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,06539354 0,09547139 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,06539354 0,0954135 ! protein polyubiquitination GO:0000209 34 16 0,000 0,06539354 0,09535567 ! glutamate metabolic process GO:0006536 22 16 0,000 0,06539354 0,09529791 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,06539354 0,09524023 ! response to osmotic stress GO:0006970 25 16 0,000 0,06539354 0,09518261 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,06539354 0,09512507 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,06539354 0,09506759 ! fructose metabolic process GO:0006000 25 16 0,000 0,06539354 0,09501018 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06539354 0,09495284 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06539354 0,09489557 ! intermediate filament-based process GO:0045103 32 16 0,000 0,06539354 0,09483837 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,06539354 0,09478124 ! axon cargo transport GO:0008088 43 16 0,000 0,06539354 0,09472418 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,06539354 0,09466718 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,06539354 0,09461026 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,06539354 0,0945534 ! DNA replication initiation GO:0006270 27 16 0,000 0,06539354 0,09449661 ! neuron recognition GO:0008038 35 16 0,000 0,06539354 0,09443989 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,06539354 0,09438324 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,06539354 0,09432665 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,06539354 0,09427014 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,06539354 0,09421369 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,06539354 0,09415731 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,06539354 0,09410099 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,06539354 0,09404474 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,06539354 0,09398856 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06539354 0,09393245 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,06539354 0,09387641 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,06539354 0,09382043 ! defense response to virus GO:0051607 37 16 0,000 0,06539354 0,09376452 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,06933677 0,0993593 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,06933677 0,09930015 ! metencephalon development GO:0022037 30 17 0,000 0,06933677 0,09924108 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,06933677 0,09918208 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,06933677 0,09912315 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,06933677 0,09906429 ! signal complex assembly GO:0007172 41 17 0,000 0,06933677 0,09900549 ! endothelial cell migration GO:0043542 28 17 0,000 0,06933677 0,09894677 ! inositol metabolic process GO:0006020 28 17 0,000 0,06933677 0,09888812 ! gene silencing by RNA GO:0031047 36 17 0,000 0,06933677 0,09882954 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,06933677 0,09877102 ! glial cell development GO:0021782 27 17 0,000 0,06933677 0,09871258 ! limbic system development GO:0021761 36 17 0,000 0,06933677 0,0986542 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,06933677 0,0985959 ! adult walking behavior GO:0007628 33 17 0,000 0,06933677 0,09853766 ! heart looping GO:0001947 30 17 0,000 0,06933677 0,09847949 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,06933677 0,09842139 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,06933677 0,09836336 ! myoblast differentiation GO:0045445 45 17 0,000 0,06933677 0,0983054 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,06933677 0,0982475 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,06933677 0,09818967 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,06933677 0,09813192 ! glycine metabolic process GO:0006544 28 17 0,000 0,06933677 0,09807423 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,06933677 0,0980166 ! NAD metabolic process GO:0019674 29 17 0,000 0,06933677 0,09795905 ! membrane budding GO:0006900 37 17 0,000 0,06933677 0,09790156 ! DNA integration GO:0015074 29 17 0,000 0,06933677 0,09784414 ! regulation of protein binding GO:0043393 33 17 0,000 0,06933677 0,09778679 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,06933677 0,0977295 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,06933677 0,09767228 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,06933677 0,09761513 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,06933677 0,09755805 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,06933677 0,09750103 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,06933677 0,09744408 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,06933677 0,09738719 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,06933677 0,09733037 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,06933677 0,09727362 ! steroid catabolic process GO:0006706 31 17 0,000 0,06933677 0,09721693 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,06933677 0,09716031 ! gas transport GO:0015669 25 17 0,000 0,06933677 0,09710376 ! organic cation transport GO:0015695 31 17 0,000 0,06933677 0,09704727 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,06933677 0,09699085 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,06933677 0,09693449 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,06933677 0,0968782 ! microspike assembly GO:0030035 36 17 0,000 0,06933677 0,09682197 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,06933677 0,09676581 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,07326348 0,10218663 ! neuron maturation GO:0042551 42 18 0,000 0,07326348 0,10212743 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,07326348 0,10206829 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,07326348 0,10200923 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,07326348 0,10195023 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,07326348 0,1018913 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,07326348 0,10183243 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,07326348 0,10177364 ! patterning of blood vessels GO:0001569 39 18 0,000 0,07326348 0,10171491 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,07326348 0,10165625 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,07326348 0,10159766 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,07326348 0,10153914 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,07326348 0,10148068 ! glutamine metabolic process GO:0006541 29 18 0,000 0,07326348 0,10142229 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,07326348 0,10136397 ! response to fungus GO:0009620 21 18 0,000 0,07326348 0,10130571 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,07326348 0,10124753 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,07326348 0,1011894 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,07326348 0,10113135 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,07326348 0,10107336 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,07326348 0,10101544 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,07326348 0,10095758 GO:0033014|tetrapyrrole biosynthetic process, ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,07326348 0,1008998 ! nerve development GO:0021675 28 18 0,000 0,07326348 0,10084207 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,07326348 0,10078442 ! protein secretion GO:0009306 39 19 0,000 0,07717376 0,1061029 ! positive regulation of translation GO:0045727 30 19 0,000 0,07717376 0,10604231 ! negative regulation of defense response GO:0031348 25 19 0,000 0,07717376 0,10598178 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,07717376 0,10592132 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,07717376 0,10586093 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,07717376 0,10580061 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,07717376 0,10574036 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,07717376 0,10568018 ! bile acid metabolic process GO:0008206 29 19 0,000 0,07717376 0,10562007 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,07717376 0,10556002 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,07717376 0,10550004 ! cerebral cortex development GO:0021987 36 19 0,000 0,07717376 0,10544013 ! pigmentation during development GO:0048066 41 19 0,000 0,07717376 0,10538029 ! actin filament bundle formation GO:0051017 42 19 0,000 0,07717376 0,10532052 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,07717376 0,10526081 ! plasma membrane fusion GO:0045026 28 19 0,000 0,07717376 0,10520118 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,07717376 0,10514161 ! peptide cross-linking GO:0018149 37 19 0,000 0,07717376 0,1050821 ! protein export from nucleus GO:0006611 36 19 0,000 0,07717376 0,10502267 ! heart process GO:0003015 30 19 0,000 0,07717376 0,1049633 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,07717376 0,104904 ! visual learning GO:0008542 36 19 0,000 0,07717376 0,10484476 ! cellular pigmentation GO:0033059 36 19 0,000 0,07717376 0,1047856 ! G1 phase GO:0051318 40 19 0,000 0,07717376 0,1047265 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,07717376 0,10466746 ! cell-cell junction organization GO:0045216 35 19 0,000 0,07717376 0,10460849 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,07717376 0,10454959 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,07717376 0,10449076 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,07717376 0,10443199 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,07717376 0,10437329 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,07717376 0,10431465 ! cilium assembly GO:0042384 37 19 0,000 0,07717376 0,10425608 ! peptide hormone secretion GO:0030072 31 19 0,000 0,07717376 0,10419757 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,08106768 0,10939362 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,08106768 0,1093323 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,08106768 0,10927105 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,08106768 0,10920987 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,08106768 0,10914876 ! cAMP metabolic process GO:0046058 36 20 0,000 0,08106768 0,10908771 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,08106768 0,10902673 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,08106768 0,10896583 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,08106768 0,10890498 ! response to alkaloid GO:0043279 38 20 0,000 0,08106768 0,10884421 ! pancreas development GO:0031016 35 20 0,000 0,08106768 0,10878351 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,08106768 0,10872287 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,08106768 0,1086623 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,08106768 0,1086018 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,08106768 0,10854136 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,08106768 0,10848099 ! body fluid secretion GO:0007589 31 20 0,000 0,08106768 0,10842069 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,08106768 0,10836046 ! peptide secretion GO:0002790 35 20 0,000 0,08106768 0,10830029 ! stem cell differentiation GO:0048863 53 20 0,000 0,08106768 0,10824019 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,08106768 0,10818016 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,08106768 0,10812019 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,08106768 0,10806029 ! sensory perception of pain GO:0019233 30 20 0,000 0,08106768 0,10800046 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,08106768 0,10794069 ! diencephalon development GO:0021536 34 20 0,000 0,08106768 0,10788099 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,08106768 0,10782135 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,08106768 0,10776178 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,08106768 0,10770228 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,08106768 0,10764284 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,08106768 0,10758347 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,08106768 0,10752416 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,08106768 0,10746492 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,08106768 0,10740574 ! regulation of glucose import GO:0046324 29 20 0,000 0,08106768 0,10734663 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,08106768 0,10728758 ! actin filament-based movement GO:0030048 43 20 0,000 0,08106768 0,1072286 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,08106768 0,10716969 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,08106768 0,10711083 ! negative regulation of translation GO:0017148 29 20 0,000 0,08106768 0,10705205 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,08106768 0,10699332 ! regulation of cell killing GO:0031341 42 21 0,000 0,08494528 0,11204954 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,08494528 0,11198814 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,08494528 0,11192681 ! hormone secretion GO:0046879 38 21 0,000 0,08494528 0,11186555 ! glycerol metabolic process GO:0006071 34 21 0,000 0,08494528 0,11180435 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,08494528 0,11174322 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,08494528 0,11168216 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,08494528 0,11162117 ! axis specification GO:0009798 38 21 0,000 0,08494528 0,11156024 ! ovarian follicle development GO:0001541 35 21 0,000 0,08494528 0,11149938 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,08494528 0,11143858 ! smooth muscle contraction GO:0006939 46 21 0,000 0,08494528 0,11137785 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,08494528 0,11131719 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,08494528 0,11125659 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,08494528 0,11119606 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,08494528 0,11113559 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,08494528 0,11107519 ! cytolysis GO:0019835 24 21 0,000 0,08494528 0,11101486 ! vasodilation GO:0042311 39 21 0,000 0,08494528 0,11095459 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,08494528 0,11089439 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,08494528 0,11083425 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,08494528 0,11077418 ! oogenesis GO:0048477 36 21 0,000 0,08494528 0,11071417 ! DNA modification GO:0006304 34 21 0,000 0,08494528 0,11065423 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,08494528 0,11059435 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! detection of biotic stimulus GO:0009595 29 21 0,000 0,08494528 0,11053453 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,08494528 0,11047479 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,08494528 0,1104151 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,08494528 0,11035548 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,08494528 0,11029593 ! collagen catabolic process GO:0030574 28 21 0,000 0,08494528 0,11023644 ! sperm-egg recognition GO:0035036 21 21 0,000 0,08494528 0,11017701 ! gut development GO:0048565 39 21 0,000 0,08494528 0,11011765 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,08880666 0,11506129 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,08880666 0,11499937 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,08880666 0,11493751 ! microtubule-based transport GO:0010970 54 22 0,000 0,08880666 0,11487571 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,08880666 0,11481398 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,08880666 0,11475232 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,08880666 0,11469073 ! regeneration GO:0031099 41 22 0,000 0,08880666 0,1146292 ! keratinization GO:0031424 28 22 0,000 0,08880666 0,11456773 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,08880666 0,11450634 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,08880666 0,114445 ! sensory perception of taste GO:0050909 28 22 0,000 0,08880666 0,11438374 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,08880666 0,11432254 ! vacuolar transport GO:0007034 36 22 0,000 0,08880666 0,1142614 ! lysosome organization GO:0007040 41 22 0,000 0,08880666 0,11420033 ! central nervous system neuron development GO:0021954 46 22 0,000 0,08880666 0,11413933 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,08880666 0,11407839 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,08880666 0,11401752 ! fucose metabolic process GO:0006004 39 22 0,000 0,08880666 0,11395671 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,08880666 0,11389596 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,08880666 0,11383528 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,08880666 0,11377467 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,08880666 0,11371412 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,08880666 0,11365363 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,08880666 0,11359321 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,08880666 0,11353285 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,08880666 0,11347256 ! sarcomere organization GO:0045214 30 22 0,000 0,08880666 0,11341233 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,08880666 0,11335216 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,08880666 0,11329206 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,08880666 0,11323202 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,08880666 0,11317205 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,08880666 0,11311214 ! protein stabilization GO:0050821 39 22 0,000 0,08880666 0,11305229 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,09265187 0,11788493 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,09265187 0,11782262 ! viral genome replication GO:0019079 41 23 0,000 0,09265187 0,11776038 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,09265187 0,1176982 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,09265187 0,11763609 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,09265187 0,11757405 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,09265187 0,11751207 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,09265187 0,11745016 ! visual behavior GO:0007632 42 23 0,000 0,09265187 0,11738831 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,09265187 0,11732652 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,09265187 0,11726481 ! response to ethanol GO:0045471 46 23 0,000 0,09265187 0,11720315 ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,09265187 0,11714156 ! peroxisome organization GO:0007031 37 23 0,000 0,09265187 0,11708004 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,09265187 0,11701858 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,09265187 0,11695719 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,09265187 0,11689586 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,09265187 0,11683459 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,09265187 0,11677339 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,09265187 0,11671225 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,09265187 0,11665118 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,09265187 0,11659017 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,09265187 0,11652922 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,09265187 0,11646834 ! fatty acid transport GO:0015908 44 23 0,000 0,09265187 0,11640752 ! platelet activation GO:0030168 37 23 0,000 0,09265187 0,11634676 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,09265187 0,11628607 ! hormone transport GO:0009914 40 23 0,000 0,09265187 0,11622544 ! cell-cell recognition GO:0009988 25 23 0,000 0,09265187 0,11616488 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,09265187 0,11610437 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,09265187 0,11604393 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,09265187 0,11598356 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,09265187 0,11592324 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,09648098 0,12065137 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,09648098 0,12058869 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,09648098 0,12052608 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,09648098 0,12046354 ! vesicle docking GO:0048278 47 24 0,000 0,09648098 0,12040105 ! spinal cord development GO:0021510 47 24 0,000 0,09648098 0,12033864 ! vacuole organization GO:0007033 43 24 0,000 0,09648098 0,12027629 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,09648098 0,120214 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,09648098 0,12015178 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,09648098 0,12008962 ! regulation of behavior GO:0050795 43 24 0,000 0,09648098 0,12002752 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,09648098 0,11996549 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,09648098 0,11990353 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,09648098 0,11984163 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,09648098 0,11977979 ! membrane depolarization GO:0051899 39 24 0,000 0,09648098 0,11971802 ! pallium development GO:0021543 49 24 0,000 0,09648098 0,11965631 ! pentose metabolic process GO:0019321 35 24 0,000 0,09648098 0,11959466 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,09648098 0,11953308 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,09648098 0,11947156 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,09648098 0,1194101 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,09648098 0,11934871 ! alditol metabolic process GO:0019400 38 24 0,000 0,09648098 0,11928738 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,09648098 0,11922611 ! regulation of amine transport GO:0051952 40 24 0,000 0,09648098 0,1191649 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,10029405 0,12381093 ! phototransduction GO:0007602 33 25 0,000 0,10029405 0,12374743 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,10029405 0,12368401 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,10029405 0,12362064 ! sperm motility GO:0030317 31 25 0,000 0,10029405 0,12355735 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,10029405 0,12349411 ! receptor metabolic process GO:0043112 46 25 0,000 0,10029405 0,12343094 ! chromosome condensation GO:0030261 45 25 0,000 0,10029405 0,12336784 ! osteoblast differentiation GO:0001649 60 25 0,000 0,10029405 0,1233048 ! neural crest cell development GO:0014032 54 25 0,000 0,10029405 0,12324183 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,10029405 0,12317892 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,10029405 0,12311607 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,10029405 0,12305329 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,10029405 0,12299057 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,10029405 0,12292791 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,10029405 0,12286532 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,10029405 0,1228028 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,10029405 0,12274033 ! telomere organization GO:0032200 43 25 0,000 0,10029405 0,12267793 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,10029405 0,1226156 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,10029405 0,12255332 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,10409117 0,1271286 ! embryonic pattern specification GO:0009880 44 26 0,000 0,10409117 0,1270641 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,10409117 0,12699967 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,10409117 0,1269353 ! initiation of viral infection GO:0019059 57 26 0,000 0,10409117 0,12687099 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,10409117 0,12680676 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,10409117 0,12674258 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,10409117 0,12667847 ! molting cycle process GO:0022404 50 26 0,000 0,10409117 0,12661443 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,10409117 0,12655045 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,10409117 0,12648654 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,10409117 0,12642269 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,10409117 0,1263589 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,10409117 0,12629518 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,10409117 0,12623152 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,10409117 0,12616793 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,10409117 0,1261044 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,10409117 0,12604094 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,10409117 0,12597754 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,10409117 0,1259142 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,10409117 0,12585093 ! blastocyst development GO:0001824 49 26 0,000 0,10409117 0,12578772 ! leukocyte proliferation GO:0070661 52 26 0,000 0,10409117 0,12572457 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,10409117 0,12566149 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,10409117 0,12559847 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,10787238 0,13009571 ! iron ion transport GO:0006826 59 27 0,000 0,10787238 0,13003053 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,10787238 0,12996542 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,10787238 0,12990037 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,10787238 0,12983539 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,10787238 0,12977047 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,10787238 0,12970562 ! autophagy GO:0006914 41 27 0,000 0,10787238 0,12964083 ! male gonad development GO:0008584 44 27 0,000 0,10787238 0,1295761 ! response to toxin GO:0009636 47 27 0,000 0,10787238 0,12951145 ! primary neural tube formation GO:0014020 51 27 0,000 0,10787238 0,12944685 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,10787238 0,12938232 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,10787238 0,12931786 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,10787238 0,12925345 ! glutathione metabolic process GO:0006749 39 27 0,000 0,10787238 0,12918912 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,10787238 0,12912484 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,10787238 0,12906064 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,11163775 0,13349922 ! circadian rhythm GO:0007623 50 28 0,000 0,11163775 0,1334329 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,11163775 0,13336665 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,11163775 0,13330046 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,11163775 0,13323434 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,11163775 0,13316829 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,11163775 0,1331023 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,11163775 0,13303637 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,11163775 0,13297051 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,11163775 0,13290472 ! synaptogenesis GO:0007416 42 28 0,000 0,11163775 0,13283899 ! lipid oxidation GO:0034440 43 28 0,000 0,11163775 0,13277332 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,11163775 0,13270773 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,11163775 0,13264219 ! translational initiation GO:0006413 65 29 0,000 0,11538736 0,13702961 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,11538736 0,13696201 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,11538736 0,13689448 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,11538736 0,13682701 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,11538736 0,1367596 ! catechol metabolic process GO:0009712 54 29 0,000 0,11538736 0,13669227 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,11538736 0,136625 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,11538736 0,13655779 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,11538736 0,13649066 ! cell fate determination GO:0001709 60 29 0,000 0,11538736 0,13642359 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,11538736 0,13635658 ! detection of light stimulus GO:0009583 38 29 0,000 0,11538736 0,13628964 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,11538736 0,13622277 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,11538736 0,13615596 ! regulation of coagulation GO:0050818 46 29 0,000 0,11538736 0,13608921 ! phenol metabolic process GO:0018958 55 30 0,000 0,11912127 0,14042419 ! zinc ion transport GO:0006829 45 30 0,000 0,11912127 0,14035542 ! membrane docking GO:0022406 61 30 0,000 0,11912127 0,14028672 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,11912127 0,14021809 ! regulation of innate immune response GO:0045088 51 30 0,000 0,11912127 0,14014952 ! acute-phase response GO:0006953 49 30 0,000 0,11912127 0,14008103 ! myofibril assembly GO:0030239 47 30 0,000 0,11912127 0,14001259 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,11912127 0,13994423 ! phospholipid transport GO:0015914 51 30 0,000 0,11912127 0,13987593 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,11912127 0,1398077 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 48 30 0,000 0,11912127 0,13973953 ! response to heat GO:0009408 50 30 0,000 0,11912127 0,13967143 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,12283954 0,143961 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,12283954 0,14389091 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,12283954 0,14382089 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,12283954 0,14375094 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,12283954 0,14368106 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,12283954 0,14361124 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,12283954 0,14354149 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,12283954 0,14347181 ! ovulation cycle process GO:0022602 49 31 0,000 0,12283954 0,1434022 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,12283954 0,14333266 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,12283954 0,14326318 ! peptide transport GO:0015833 55 31 0,000 0,12283954 0,14319377 ! iron ion homeostasis GO:0055072 54 31 0,000 0,12283954 0,14312442 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,12283954 0,14305515 ! mesoderm formation GO:0001707 69 31 0,000 0,12283954 0,14298594 ! natural killer cell activation GO:0030101 45 31 0,000 0,12283954 0,1429168 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,12283954 0,14284772 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,12283954 0,14277871 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,12283954 0,14270977 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,12283954 0,1426409 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,12283954 0,14257209 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,12654224 0,14679876 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,12654224 0,14672801 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,12654224 0,14665734 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,12654224 0,14658672 ! cholesterol transport GO:0030301 56 32 0,000 0,12654224 0,14651618 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,12654224 0,14644571 ! spliceosome assembly GO:0000245 67 32 0,000 0,12654224 0,1463753 ! spindle organization GO:0007051 46 32 0,000 0,12654224 0,14630496 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,12654224 0,14623469 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,12654224 0,14616449 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,12654224 0,14609435 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,12654224 0,14602428 ! muscle cell development GO:0055001 49 32 0,000 0,12654224 0,14595428 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,12654224 0,14588434 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,12654224 0,14581448 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,12654224 0,14574468 ! ovulation cycle GO:0042698 51 32 0,000 0,12654224 0,14567494 ! hindbrain development GO:0030902 61 32 0,000 0,12654224 0,14560527 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,12654224 0,14553567 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,12654224 0,14546614 ! gene silencing GO:0016458 65 32 0,000 0,12654224 0,14539667 ! protein targeting to membrane GO:0006612 68 33 0,000 0,13022943 0,14956182 ! ceramide metabolic process GO:0006672 64 33 0,000 0,13022943 0,14949046 ! formation of primary germ layer GO:0001704 72 33 0,000 0,13022943 0,14941917 ! cell fate specification GO:0001708 52 33 0,000 0,13022943 0,14934795 ! sterol transport GO:0015918 57 33 0,000 0,13022943 0,1492768 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,13022943 0,14920572 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,13022943 0,1491347 ! adult locomotory behavior GO:0008344 59 33 0,000 0,13022943 0,14906375 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,13022943 0,14899287 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,13022943 0,14892206 ! glial cell differentiation GO:0010001 63 34 0,000 0,13390118 0,15304809 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,13390118 0,15297542 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,13390118 0,15290282 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,13390118 0,15283028 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,13390118 0,15275782 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,13390118 0,15268542 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,13390118 0,15261309 ! mismatch repair GO:0006298 46 34 0,000 0,13390118 0,15254083 ! spermatid development GO:0007286 63 34 0,000 0,13390118 0,15246864 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,13390118 0,15239652 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,13390118 0,15232446 ! placenta development GO:0001890 53 34 0,000 0,13390118 0,15225247 ! regulation of muscle development GO:0048634 70 35 0,000 0,13755755 0,15633607 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,13755755 0,15626226 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,13755755 0,15618851 ! female gonad development GO:0008585 58 35 0,000 0,13755755 0,15611484 ! telencephalon development GO:0021537 68 35 0,000 0,13755755 0,15604123 ! cytokine production GO:0001816 59 35 0,000 0,13755755 0,1559677 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,13755755 0,15589423 ! neural tube formation GO:0001841 67 35 0,000 0,13755755 0,15582084 ! vesicle localization GO:0051648 64 35 0,000 0,13755755 0,15574751 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,1411986 0,15979484 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,1411986 0,15971972 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,1411986 0,15964466 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,1411986 0,15956967 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,1411986 0,15949476 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,1411986 0,15941991 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,1411986 0,15934514 ! aerobic respiration GO:0009060 55 36 0,000 0,1411986 0,15927043 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,1411986 0,1591958 ! RNA export from nucleus GO:0006405 56 37 0,000 0,1448244 0,16320727 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,1448244 0,16313086 ! meiosis I GO:0007127 65 37 0,000 0,1448244 0,16305452 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,1448244 0,16297826 ! sister chromatid segregation GO:0000819 58 37 0,000 0,1448244 0,16290206 ! actomyosin structure organization GO:0031032 62 37 0,000 0,1448244 0,16282594 ! organic anion transport GO:0015711 68 37 0,000 0,1448244 0,16274989 ! tissue remodeling GO:0048771 76 37 0,000 0,1448244 0,16267391 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,1448244 0,162598 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,1448244 0,16252216 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,1448244 0,16244639 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,1448244 0,1623707 ! glycogen metabolic process GO:0005977 61 37 0,000 0,1448244 0,16229507 ! spermatid differentiation GO:0048515 66 37 0,000 0,1448244 0,16221951 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,14843502 0,16618644 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,14843502 0,16610914 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,14843502 0,16603192 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,14843502 0,16595477 ! nucleus organization GO:0006997 67 38 0,000 0,14843502 0,16587769 ! lipid homeostasis GO:0055088 67 38 0,000 0,14843502 0,16580068 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,14843502 0,16572374 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,14843502 0,16564687 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,14843502 0,16557008 ! glucan metabolic process GO:0044042 62 38 0,000 0,14843502 0,16549335 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,15203051 0,16942353 ! ear morphogenesis GO:0042471 60 39 0,000 0,15203051 0,1693451 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,15203051 0,16926673 ! ion transmembrane transport GO:0034220 66 39 0,000 0,15203051 0,16918844 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,15203051 0,16911022 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,15203051 0,16903207 ! RNA modification GO:0009451 57 39 0,000 0,15203051 0,168954 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,15203051 0,168876 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,15561094 0,17277338 ! negative regulation of binding GO:0051100 72 40 0,000 0,15561094 0,17269369 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,15561094 0,17261407 ! maintenance of protein location GO:0045185 91 40 0,000 0,15561094 0,17253452 ! cytokinesis GO:0000910 72 40 0,000 0,15561094 0,17245505 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,15917637 0,1763252 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,15917637 0,17624406 ! gliogenesis GO:0042063 88 41 0,000 0,15917637 0,17616299 ! female gamete generation GO:0007292 61 41 0,000 0,15917637 0,17608199 ! polyol metabolic process GO:0019751 66 41 0,000 0,15917637 0,17600107 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,15917637 0,17592023 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,16272686 0,17976163 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,16272686 0,17967913 ! regulation of tube size GO:0035150 71 42 0,000 0,16272686 0,17959671 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,16272686 0,17951436 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,16272686 0,17943209 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,16272686 0,1793499 ! neuron migration GO:0001764 79 42 0,000 0,16272686 0,17926778 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,16272686 0,17918573 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,16626248 0,1829952 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,16626248 0,18291153 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,16626248 0,18282793 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,16626248 0,18274441 ! glucose transport GO:0015758 65 43 0,000 0,16626248 0,18266097 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,16626248 0,1825776 ! neural tube development GO:0021915 77 43 0,000 0,16626248 0,18249431 ! striated muscle contraction GO:0006941 77 43 0,000 0,16626248 0,18241109 ! phagocytosis GO:0006909 90 43 0,000 0,16626248 0,18232795 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,16626248 0,18224488 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,16978328 0,18601939 ! hexose transport GO:0008645 67 44 0,000 0,16978328 0,18593472 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 0,000 0,16978328 0,18585012 ! biopolymer methylation GO:0043414 84 44 0,000 0,16978328 0,18576561 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,16978328 0,18568117 ! developmental growth GO:0048589 82 44 0,000 0,16978328 0,18559681 ! maintenance of location in cell GO:0051651 97 44 0,000 0,16978328 0,18551252 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,17328933 0,18925744 ! glycolysis GO:0006096 65 45 0,000 0,17328933 0,18917157 ! leukocyte migration GO:0050900 68 45 0,000 0,17328933 0,18908578 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,17328933 0,18900006 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,17328933 0,18891442 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,17328933 0,18882887 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,17328933 0,18874338 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,17328933 0,18865798 ! cell growth GO:0016049 84 45 0,000 0,17328933 0,18857265 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,1767807 0,19228497 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,1767807 0,19219808 ! pigmentation GO:0043473 100 46 0,000 0,1767807 0,19211127 ! endosome transport GO:0016197 108 47 0,000 0,18025743 0,19580107 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,18025743 0,19571271 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,18025743 0,19562444 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,18025743 0,19553624 ! JNK cascade GO:0007254 91 47 0,000 0,18025743 0,19544812 ! methylation GO:0032259 90 47 0,000 0,18025743 0,19536008 ! protein homooligomerization GO:0051260 76 47 0,000 0,18025743 0,19527212 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,18371959 0,1989331 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,18371959 0,19884361 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,18371959 0,1987542 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,18716725 0,20239299 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,18716725 0,20230207 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,18716725 0,20221123 ! regulation of ion transport GO:0043269 77 49 0,000 0,18716725 0,20212047 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,18716725 0,20202979 ! peptide metabolic process GO:0006518 76 49 0,000 0,18716725 0,2019392 ! response to temperature stimulus GO:0009266 76 49 0,000 0,18716725 0,20184868 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,18716725 0,20175825 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,18716725 0,20166789 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,18716725 0,20157762 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,18716725 0,20148743 ! neuromuscular process GO:0050905 99 50 0,000 0,19060046 0,20509155 ! inner ear development GO:0048839 79 50 0,000 0,19060046 0,20499987 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,19060046 0,20490827 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,19060046 0,20481675 ! viral infectious cycle GO:0019058 99 51 0,000 0,19401928 0,2083975 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,19401928 0,20830451 ! excretion GO:0007588 83 51 0,000 0,19401928 0,2082116 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,19401928 0,20811877 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,19401928 0,20802602 ! vesicle organization GO:0016050 107 51 0,000 0,19401928 0,20793336 ! regulation of cell shape GO:0008360 125 51 0,000 0,19401928 0,20784078 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,19742378 0,21139369 ! membrane fusion GO:0006944 110 52 0,000 0,19742378 0,21129965 ! amino acid activation GO:0043038 92 52 0,000 0,19742378 0,2112057 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,20081401 0,21473711 ! RNA catabolic process GO:0006401 93 53 0,000 0,20081401 0,21464172 ! regulation of translational initiation GO:0006446 82 53 0,000 0,20081401 0,2145464 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,20081401 0,21445118 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,20081401 0,21435603 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,20081401 0,21426098 ! cell maturation GO:0048469 100 53 0,000 0,20081401 0,214166 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,20081401 0,21407111 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,20419003 0,21757361 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,20419003 0,21747729 ! cell recognition GO:0008037 85 54 0,000 0,20419003 0,21738106 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,20419003 0,21728492 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,20419003 0,21718886 ! chloride transport GO:0006821 90 55 0,000 0,20755189 0,22066719 ! glucose catabolic process GO:0006007 82 55 0,000 0,20755189 0,22056973 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,20755189 0,22047234 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,20755189 0,22037505 ! gastrulation GO:0007369 112 55 0,000 0,20755189 0,22027784 ! RNA elongation GO:0006354 79 55 0,000 0,20755189 0,22018071 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,20755189 0,22008367 ! regulation of actin filament length GO:0030832 105 56 0,000 0,21089967 0,22353507 ! sensory perception of smell GO:0007608 80 56 0,000 0,21089967 0,22343664 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,21089967 0,2233383 ! proton transport GO:0015992 94 56 0,000 0,21089967 0,22324004 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,21089967 0,22314187 ! maintenance of location GO:0051235 118 57 0,000 0,21423342 0,2265695 ! hydrogen transport GO:0006818 97 58 0,000 0,21755319 0,22997934 ! regulation of endocytosis GO:0030100 91 58 0,000 0,21755319 0,22987834 ! adult behavior GO:0030534 99 58 0,000 0,21755319 0,22977743 ! regulation of cellular component size GO:0032535 109 59 0,000 0,22085905 0,23316668 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,22085905 0,23306442 GO:0032313|regulation of Rab GTPase activity, ! DNA catabolic process GO:0006308 86 59 0,000 0,22085905 0,23296224 ! establishment of organelle localization GO:0051656 109 59 0,000 0,22085905 0,23286015 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,22415105 0,23622752 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,22415105 0,23612409 ! regulation of heart contraction GO:0008016 110 60 0,000 0,22415105 0,23602075 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,22742925 0,23936779 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,22742925 0,23926312 ! mesoderm development GO:0007498 119 61 0,000 0,22742925 0,23915855 ! tRNA processing GO:0008033 89 61 0,000 0,22742925 0,23905407 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,22742925 0,23894968 ! ear development GO:0043583 103 62 0,000 0,2306937 0,2422737 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,2306937 0,242168 ! gonad development GO:0008406 98 62 0,000 0,2306937 0,24206238 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,2306937 0,24195686 ! regulation of mitosis GO:0007088 105 63 0,000 0,23394447 0,24525943 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,23394447 0,24515261 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,23394447 0,24504589 ! detection of external stimulus GO:0009581 91 63 0,000 0,23394447 0,24493925 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,23394447 0,24483271 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,23394447 0,24472626 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,23718161 0,24800476 ! cell redox homeostasis GO:0045454 102 64 0,000 0,23718161 0,24789703 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,23718161 0,24778939 ! single fertilization GO:0007338 75 64 0,000 0,23718161 0,24768184 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,24040518 0,25093921 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,24040518 0,25083039 ! germ cell development GO:0007281 118 65 0,000 0,24040518 0,25072166 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,24040518 0,25061303 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,24361524 0,2538494 ! actin filament organization GO:0007015 148 66 0,000 0,24361524 0,25373951 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,24361524 0,25362971 ! developmental maturation GO:0021700 116 66 0,000 0,24361524 0,25352001 ! chromosome segregation GO:0007059 113 67 0,000 0,24681183 0,25673552 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,24681183 0,25662457 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,24681183 0,25651372 ! hexose catabolic process GO:0019320 104 67 0,000 0,24681183 0,25640296 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,24681183 0,2562923 ! adaptive immune response GO:0002250 119 67 0,000 0,24681183 0,25618174 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! amino acid transport GO:0006865 125 68 0,000 0,24999502 0,25937388 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,24999502 0,25926208 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,24999502 0,25915038 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,24999502 0,25903877 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,24999502 0,25892726 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,24999502 0,25881584 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,25316487 0,2619848 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,25316487 0,26187217 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,25316487 0,26175963 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,25316487 0,26164719 ! antigen processing and presentation GO:0019882 104 69 0,000 0,25316487 0,26153485 ! amine catabolic process GO:0009310 117 71 0,000 0,25946473 0,26792796 ! humoral immune response GO:0006959 109 71 0,000 0,25946473 0,26781302 ! acute inflammatory response GO:0002526 113 72 0,000 0,26259487 0,27092764 ! carbohydrate transport GO:0008643 110 72 0,000 0,26259487 0,27081151 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,26259487 0,27069548 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,26259487 0,27057955 ! regulation of blood pressure GO:0008217 125 73 0,000 0,26571187 0,27367413 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,26571187 0,27355702 ! fertilization GO:0009566 90 73 0,000 0,26571187 0,27344002 ! transition metal ion transport GO:0000041 126 74 0,000 0,26881581 0,27651596 ! neurotransmitter transport GO:0006836 123 74 0,000 0,26881581 0,27639779 ! meiosis GO:0007126 121 74 0,000 0,26881581 0,27627972 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,26881581 0,27616175 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,26881581 0,27604389 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,26881581 0,27592612 ! organelle localization GO:0051640 136 74 0,000 0,26881581 0,27580846 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,27190672 0,27886086 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,27190672 0,27874204 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,27190672 0,27862333 ! meiotic cell cycle GO:0051321 122 75 0,000 0,27190672 0,27850471 ! rhythmic process GO:0048511 128 75 0,000 0,27190672 0,2783862 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,27498467 0,28141775 ! defense response to bacterium GO:0042742 89 76 0,000 0,27498467 0,2812981 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,27498467 0,28117855 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,27498467 0,2810591 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,27804972 0,28407118 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,27804972 0,2839506 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,27804972 0,28383013 ! blood coagulation GO:0007596 146 78 0,000 0,2811019 0,28682408 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,2811019 0,28670249 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,2811019 0,28658101 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,28414129 0,28955694 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,28414129 0,28943435 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,28716792 0,29239358 ! muscle cell differentiation GO:0042692 159 80 0,000 0,28716792 0,29226989 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,28716792 0,29214631 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,29018186 0,29508772 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,29018186 0,29496306 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,29318316 0,29788795 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,29318316 0,29776221 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,29318316 0,29763657 ! regulation of lyase activity GO:0051339 160 83 0,000 0,29617186 0,30054386 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,29914803 0,30343598 ! hemostasis GO:0007599 158 84 0,000 0,29914803 0,30330811 ! regulation of ligase activity GO:0051340 142 84 0,000 0,29914803 0,30318035 ! nucleosome assembly GO:0006334 122 85 0,000 0,30211171 0,30605506 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,30211171 0,30592625 ! amine biosynthetic process GO:0009309 138 86 0,000 0,30506295 0,3087848 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,30506295 0,30865495 ! chromatin assembly GO:0031497 124 86 0,000 0,30506295 0,30852521 ! alcohol catabolic process GO:0046164 130 86 0,000 0,30506295 0,30839557 ! amine transport GO:0015837 155 86 0,000 0,30506295 0,30826605 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,30800182 0,31110511 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cellular respiration GO:0045333 135 88 0,000 0,31092835 0,31392934 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,31092835 0,31379765 ! cellular defense response GO:0006968 114 89 0,000 0,3138426 0,316606 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,3138426 0,3164733 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,31674463 0,31926584 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,31674463 0,31913215 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,31674463 0,31899856 ! sterol metabolic process GO:0016125 152 91 0,000 0,31963447 0,32177428 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,31963447 0,32163971 ! nucleosome organization GO:0034728 138 92 0,000 0,32251219 0,32439981 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,32251219 0,32426424 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,32537784 0,3270088 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,32537784 0,32687226 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,32823145 0,32960137 ! forebrain development GO:0030900 188 95 0,000 0,3310731 0,33231617 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,33390281 0,33501675 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,33390281 0,3348771 ! detection of stimulus GO:0051606 151 96 0,000 0,33390281 0,33473757 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,33672065 0,33742186 ! response to virus GO:0009615 160 98 0,000 0,33952666 0,34009207 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,33952666 0,33995054 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,33952666 0,33980913 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,3423209 0,34246323 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,3423209 0,3423209