pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6521-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! prostate gland development GO:0030850 5 5 2,000 7,578E-06 0,01396577 ! CTP metabolic process GO:0046036 5 5 2,000 7,578E-06 6,983E-03 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! GTP metabolic process GO:0046039 5 5 2,000 7,578E-06 4,655E-03 ! amyloid precursor protein catabolic process GO:0042987 5 5 2,000 7,578E-06 3,491E-03 ! regulation of lipid kinase activity GO:0043550 6 6 2,000 1,505E-05 5,549E-03 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 2,000 1,505E-05 4,624E-03 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! cellular response to oxidative stress GO:0034599 19 19 3,000 2,377E-05 6,259E-03 ! amyloid precursor protein metabolic process GO:0042982 7 7 2,000 2,617E-05 6,029E-03 ! membrane protein ectodomain proteolysis GO:0006509 7 7 2,000 2,617E-05 5,359E-03 GO:0033619|membrane protein proteolysis, ! positive regulation of cell motion GO:0051272 39 39 4,000 2,682E-05 4,943E-03 ! cell cycle checkpoint GO:0000075 42 41 4,000 3,442E-05 5,766E-03 ! hemopoiesis GO:0030097 104 100 6,000 3,499E-05 5,374E-03 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 2,000 4,159E-05 5,897E-03 ! negative regulation of cell cycle process GO:0010948 9 9 2,000 6,198E-05 8,159E-03 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 2,000 6,198E-05 7,615E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 2,000 6,198E-05 7,139E-03 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 2,000 6,198E-05 6,719E-03 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 2,000 6,198E-05 6,346E-03 ! glucose homeostasis GO:0042593 24 24 3,000 6,293E-05 6,105E-03 GO:0033500|carbohydrate homeostasis, ! regulation of cell motion GO:0051270 79 79 5,000 8,352E-05 7,696E-03 ! protein stabilization GO:0050821 10 10 2,000 8,795E-05 7,719E-03 ! interphase of mitotic cell cycle GO:0051329 52 51 4,000 1,004E-04 8,414E-03 GO:0051325|interphase, ! myeloid leukocyte differentiation GO:0002573 12 11 2,000 1,201E-04 9,626E-03 ! signal complex assembly GO:0007172 11 11 2,000 1,201E-04 9,225E-03 ! response to hypoxia GO:0001666 53 53 4,000 1,21E-04 8,916E-03 ! response to oxygen levels GO:0070482 55 54 4,000 1,323E-04 9,381E-03 ! establishment of organelle localization GO:0051656 31 30 3,000 1,557E-04 0,01062509 ! glycoprotein catabolic process GO:0006516 13 12 2,000 1,591E-04 0,01047301 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 2,000 1,591E-04 0,01011187 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 2,000 1,591E-04 9,775E-03 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 2,000 2,055E-04 0,01221578 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 2,000 2,055E-04 0,01183403 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 3,000 2,872E-04 0,01604048 ! positive regulation of cell migration GO:0030335 36 36 3,000 3,209E-04 0,01739321 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 2,000 3,226E-04 0,01698568 ! meiosis GO:0007126 37 37 3,000 3,573E-04 0,01829023 GO:0051327|M phase of meiotic cell cycle, ! lung development GO:0030324 38 37 3,000 3,573E-04 0,0177959 ! cellular response to reactive oxygen species GO:0034614 16 16 2,000 3,944E-04 0,01912744 ! cellular response to nutrient levels GO:0031669 16 16 2,000 3,944E-04 0,01863699 ! meiotic cell cycle GO:0051321 38 38 3,000 3,965E-04 0,01827016 ! respiratory tube development GO:0030323 40 39 3,000 4,388E-04 0,01972385 ! respiratory system development GO:0060541 40 39 3,000 4,388E-04 0,01925423 ! tissue remodeling GO:0048771 17 17 2,000 4,757E-04 0,0203895 ! regulation of cell migration GO:0030334 71 71 4,000 4,826E-04 0,02021361 ! myeloid cell differentiation GO:0030099 42 40 3,000 4,842E-04 0,01982885 ! organelle localization GO:0051640 41 40 3,000 4,842E-04 0,01939779 ! meiosis I GO:0007127 18 18 2,000 5,671E-04 0,02223685 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 2,000 5,671E-04 0,02177359 ! cellular response to extracellular stimulus GO:0031668 18 18 2,000 5,671E-04 0,02132923 ! regulation of endothelial cell proliferation GO:0001936 19 19 2,000 6,69E-04 0,02465759 ! ribonucleoside metabolic process GO:0009119 19 19 2,000 6,69E-04 0,02417411 ! regulation of protein stability GO:0031647 19 19 2,000 6,69E-04 0,02370922 ! negative regulation of binding GO:0051100 21 20 2,000 7,818E-04 0,02718584 ! regulation of locomotion GO:0040012 79 79 4,000 7,89E-04 0,02692967 ! hemoglobin biosynthetic process GO:0042541 5 5 1,000 8,367E-04 0,02803633 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 8,367E-04 0,02753569 ! filopodium assembly GO:0046847 7 5 1,000 8,367E-04 0,0270526 GO:0030035|microspike assembly, ! mRNA stabilization GO:0048255 5 5 1,000 8,367E-04 0,02658618 GO:0043489|RNA stabilization, ! memory GO:0007613 5 5 1,000 8,367E-04 0,02613557 ! dopamine receptor signaling pathway GO:0007212 5 5 1,000 8,367E-04 0,02569997 ! heart looping GO:0001947 5 5 1,000 8,367E-04 0,02527866 ! receptor clustering GO:0043113 5 5 1,000 8,367E-04 0,02487094 ! actin cytoskeleton reorganization GO:0031532 5 5 1,000 8,367E-04 0,02447616 ! positive regulation of exocytosis GO:0045921 6 5 1,000 8,367E-04 0,02409372 ! cellular glucose homeostasis GO:0001678 5 5 1,000 8,367E-04 0,02372305 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 1,000 8,367E-04 0,02336361 ! protein heterooligomerization GO:0051291 5 5 1,000 8,367E-04 0,0230149 ! enucleate erythrocyte differentiation GO:0043353 6 5 1,000 8,367E-04 0,02267645 ! synaptic vesicle exocytosis GO:0016079 6 5 1,000 8,367E-04 0,0223478 ! positive regulation of monooxygenase activity GO:0032770 5 5 1,000 8,367E-04 0,02202855 ! postreplication repair GO:0006301 5 5 1,000 8,367E-04 0,02171829 ! DNA methylation GO:0006306 5 5 1,000 8,367E-04 0,02141664 GO:0006305|DNA alkylation, ! regulation of hormone metabolic process GO:0032350 5 5 1,000 8,367E-04 0,02112327 ! cellular response to nutrient GO:0031670 5 5 1,000 8,367E-04 0,02083782 ! peptidyl-lysine modification GO:0018205 5 5 1,000 8,367E-04 0,02055998 ! positive regulation of erythrocyte differentiation GO:0045648 5 5 1,000 8,367E-04 0,02028945 ! positive regulation of epidermis development GO:0045684 5 5 1,000 8,367E-04 0,02002595 ! regulation of epidermal cell differentiation GO:0045604 5 5 1,000 8,367E-04 0,01976921 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 8,367E-04 0,01951897 ! B cell receptor signaling pathway GO:0050853 5 5 1,000 8,367E-04 0,01927498 ! nucleus localization GO:0051647 5 5 1,000 8,367E-04 0,01903702 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 2,000 9,061E-04 0,02036429 ! Notch signaling pathway GO:0007219 22 21 2,000 9,061E-04 0,02011894 ! actin filament organization GO:0007015 50 48 3,000 9,75E-04 0,02139285 ! cytokinesis GO:0000910 23 22 2,000 1,042E-03 0,02259707 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 2,000 1,042E-03 0,02233432 ! leukocyte differentiation GO:0002521 50 49 3,000 1,054E-03 0,02233545 ! cell cycle arrest GO:0007050 49 49 3,000 1,054E-03 0,02208164 ! mitotic cell cycle checkpoint GO:0007093 24 23 2,000 1,191E-03 0,02465465 ! cell projection assembly GO:0030031 25 23 2,000 1,191E-03 0,02438071 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 1,247E-03 0,02526511 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 1,000 1,247E-03 0,02499049 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 1,247E-03 0,02472177 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 1,247E-03 0,02445877 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 1,000 1,247E-03 0,02420131 ! L-serine metabolic process GO:0006563 6 6 1,000 1,247E-03 0,02394921 ! regulation of vascular permeability GO:0043114 6 6 1,000 1,247E-03 0,02370232 ! regulation of bone resorption GO:0045124 6 6 1,000 1,247E-03 0,02346046 ! intestinal absorption GO:0050892 6 6 1,000 1,247E-03 0,02322348 ! serine family amino acid biosynthetic process GO:0009070 6 6 1,000 1,247E-03 0,02299125 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 1,247E-03 0,02276361 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! androgen receptor signaling pathway GO:0030521 24 24 2,000 1,352E-03 0,02442314 ! negative regulation of cell cycle GO:0045786 92 91 4,000 1,495E-03 0,0267463 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 1,736E-03 0,03076424 ! pteridine and derivative biosynthetic process GO:0042559 7 7 1,000 1,736E-03 0,03047125 ! regulation of chemokine production GO:0032642 7 7 1,000 1,736E-03 0,03018379 ! hemoglobin metabolic process GO:0020027 7 7 1,000 1,736E-03 0,0299017 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 1,736E-03 0,02962483 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of exocytosis GO:0017157 8 7 1,000 1,736E-03 0,02935304 ! platelet activation GO:0030168 8 7 1,000 1,736E-03 0,0290862 ! regulation of macrophage differentiation GO:0045649 8 7 1,000 1,736E-03 0,02882416 ! regulation of mRNA stability GO:0043488 7 7 1,000 1,736E-03 0,0285668 ! T cell receptor signaling pathway GO:0050852 7 7 1,000 1,736E-03 0,028314 ! response to cold GO:0009409 7 7 1,000 1,736E-03 0,02806563 ! reproductive developmental process GO:0003006 56 56 3,000 1,741E-03 0,02790217 ! regulation of binding GO:0051098 60 57 3,000 1,86E-03 0,02954365 ! learning or memory GO:0007611 28 27 2,000 1,915E-03 0,03016476 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 2,301E-03 0,03593578 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 2,301E-03 0,0356338 ! sex determination GO:0007530 8 8 1,000 2,301E-03 0,03533685 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 1,000 2,301E-03 0,03504481 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 2,301E-03 0,03475756 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 1,000 2,301E-03 0,03447498 ! regulation of RNA stability GO:0043487 8 8 1,000 2,301E-03 0,03419695 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 1,000 2,301E-03 0,03392338 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 2,301E-03 0,03365414 ! aromatic compound biosynthetic process GO:0019438 8 8 1,000 2,301E-03 0,03338915 ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 2,301E-03 0,0331283 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 2,361E-03 0,03372792 ! response to reactive oxygen species GO:0000302 31 30 2,000 2,606E-03 0,036942 ! positive regulation of response to external stimulus GO:0032103 30 30 2,000 2,606E-03 0,03666 ! negative regulation of cellular component organization GO:0051129 65 63 3,000 2,69E-03 0,03755604 ! nucleoside metabolic process GO:0009116 31 31 2,000 2,866E-03 0,03971402 ! regulation of myeloid cell differentiation GO:0045637 32 31 2,000 2,866E-03 0,03941764 ! negative regulation of cell motion GO:0051271 31 31 2,000 2,866E-03 0,03912566 ! positive regulation of cell projection organization GO:0031346 9 9 1,000 2,94E-03 0,03984806 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 2,94E-03 0,03955719 ! regulation of cell-cell adhesion GO:0022407 9 9 1,000 2,94E-03 0,03927055 ! pigmentation during development GO:0048066 9 9 1,000 2,94E-03 0,03898803 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 2,94E-03 0,03870954 ! prostaglandin metabolic process GO:0006693 9 9 1,000 2,94E-03 0,038435 GO:0006692|prostanoid metabolic process, ! histone acetylation GO:0016573 9 9 1,000 2,94E-03 0,03816433 ! positive regulation of oxidoreductase activity GO:0051353 9 9 1,000 2,94E-03 0,03789745 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 2,94E-03 0,03763427 ! regulation of leukocyte migration GO:0002685 9 9 1,000 2,94E-03 0,03737473 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 2,94E-03 0,03711874 ! positive regulation of cellular component organization GO:0051130 65 65 3,000 3,015E-03 0,03780358 ! regulation of vesicle-mediated transport GO:0060627 33 32 2,000 3,142E-03 0,03912144 ! protein maturation by peptide bond cleavage GO:0051605 32 32 2,000 3,142E-03 0,03885888 ! striated muscle tissue development GO:0014706 69 67 3,000 3,367E-03 0,04136493 ! regulation of protein ubiquitination GO:0031396 10 10 1,000 3,654E-03 0,04459368 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 1,000 3,654E-03 0,0443003 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 3,654E-03 0,04401076 ! pteridine and derivative metabolic process GO:0042558 10 10 1,000 3,654E-03 0,04372497 ! reciprocal meiotic recombination GO:0007131 10 10 1,000 3,654E-03 0,04344287 ! calcium-independent cell-cell adhesion GO:0016338 10 10 1,000 3,654E-03 0,04316439 ! neuromuscular junction development GO:0007528 10 10 1,000 3,654E-03 0,04288946 ! regulation of protein binding GO:0043393 11 10 1,000 3,654E-03 0,04261801 ! synaptic vesicle transport GO:0048489 11 10 1,000 3,654E-03 0,04234997 ! regulation of erythrocyte differentiation GO:0045646 10 10 1,000 3,654E-03 0,04208528 ! regulation of epidermis development GO:0045682 10 10 1,000 3,654E-03 0,04182389 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 3,654E-03 0,04156571 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 3,654E-03 0,04131071 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 1,000 3,654E-03 0,04105881 ! regulation of lipid metabolic process GO:0019216 34 34 2,000 3,74E-03 0,04177954 ! regulation of mitotic cell cycle GO:0007346 72 69 3,000 3,745E-03 0,04157857 ! positive regulation of transport GO:0051050 71 70 3,000 3,945E-03 0,04353223 ! muscle tissue development GO:0060537 72 70 3,000 3,945E-03 0,04327311 ! regulation of mitosis GO:0007088 37 36 2,000 4,404E-03 0,04803225 GO:0051783|regulation of nuclear division, ! protein amino acid acetylation GO:0006473 11 11 1,000 4,439E-03 0,04812242 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 4,439E-03 0,047841 GO:0032388|positive regulation of intracellular transport, ! regulation of transmembrane transporter activity GO:0022898 11 11 1,000 4,439E-03 0,04756285 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! cellular response to starvation GO:0009267 11 11 1,000 4,439E-03 0,04728792 ! digestive system process GO:0022600 11 11 1,000 4,439E-03 0,04701615 ! G1/S transition checkpoint GO:0031575 12 11 1,000 4,439E-03 0,04674749 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 4,439E-03 0,04648188 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 4,439E-03 0,04621927 GO:0006109|regulation of carbohydrate metabolic process, ! muscle maintenance GO:0046716 12 11 1,000 4,439E-03 0,04595961 ! proximal/distal pattern formation GO:0009954 11 11 1,000 4,439E-03 0,04570285 ! regulation of transcription factor activity GO:0051090 38 37 2,000 4,762E-03 0,04875332 GO:0090046|regulation of transcription regulator activity, ! negative regulation of growth GO:0045926 37 37 2,000 4,762E-03 0,04848396 ! response to oxidative stress GO:0006979 76 75 3,000 5,051E-03 0,05115187 ! cell-matrix adhesion GO:0007160 39 38 2,000 5,136E-03 0,05172213 ! chromosome segregation GO:0007059 38 38 2,000 5,136E-03 0,05144104 ! urogenital system development GO:0001655 38 38 2,000 5,136E-03 0,05116298 ! steroid hormone receptor signaling pathway GO:0030518 38 38 2,000 5,136E-03 0,05088791 ! regulation of homeostatic process GO:0032844 38 38 2,000 5,136E-03 0,05061578 ! positive regulation of angiogenesis GO:0045766 12 12 1,000 5,295E-03 0,05190598 ! collagen metabolic process GO:0032963 12 12 1,000 5,295E-03 0,05163134 ! C21-steroid hormone metabolic process GO:0008207 13 12 1,000 5,295E-03 0,0513596 ! positive regulation of endocytosis GO:0045807 12 12 1,000 5,295E-03 0,0510907 ! regulation of chromosome organization GO:0033044 12 12 1,000 5,295E-03 0,0508246 ! somitogenesis GO:0001756 13 12 1,000 5,295E-03 0,05056126 ! G1 phase GO:0051318 13 12 1,000 5,295E-03 0,05030064 ! neurotransmitter secretion GO:0007269 14 12 1,000 5,295E-03 0,05004269 ! spermatid differentiation GO:0048515 13 12 1,000 5,295E-03 0,04978737 GO:0007286|spermatid development, ! cytokine-mediated signaling pathway GO:0019221 39 39 2,000 5,527E-03 0,05170824 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 2,000 5,936E-03 0,05525308 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 6,22E-03 0,05760659 ! negative regulation of protein modification process GO:0031400 13 13 1,000 6,22E-03 0,05731856 ! vasculogenesis GO:0001570 13 13 1,000 6,22E-03 0,05703339 ! negative regulation of DNA replication GO:0008156 13 13 1,000 6,22E-03 0,05675105 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 1,000 6,22E-03 0,05647149 ! receptor metabolic process GO:0043112 14 13 1,000 6,22E-03 0,05619467 ! actin filament bundle formation GO:0051017 13 13 1,000 6,22E-03 0,05592055 ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 6,22E-03 0,05564909 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 6,22E-03 0,05538025 ! negative regulation of phosphorylation GO:0042326 13 13 1,000 6,22E-03 0,055114 ! positive regulation of locomotion GO:0040017 13 13 1,000 6,22E-03 0,0548503 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 1,000 6,22E-03 0,05458911 ! tube development GO:0035295 83 81 3,000 6,634E-03 0,0579437 ! cell-substrate adhesion GO:0031589 43 42 2,000 6,807E-03 0,05917642 ! cellular iron ion homeostasis GO:0006879 14 14 1,000 7,214E-03 0,06241566 ! protein amino acid acylation GO:0043543 14 14 1,000 7,214E-03 0,062124 ! negative regulation of epithelial cell proliferation GO:0050680 14 14 1,000 7,214E-03 0,06183505 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 1,000 7,214E-03 0,06154878 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 1,000 7,214E-03 0,06126514 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! negative regulation of phosphorus metabolic process GO:0010563 14 14 1,000 7,214E-03 0,06098411 GO:0045936|negative regulation of phosphate metabolic process, ! peptide cross-linking GO:0018149 14 14 1,000 7,214E-03 0,06070564 ! regulation of behavior GO:0050795 14 14 1,000 7,214E-03 0,06042971 ! DNA modification GO:0006304 14 14 1,000 7,214E-03 0,06015627 ! positive regulation of inflammatory response GO:0050729 14 14 1,000 7,214E-03 0,0598853 ! reproductive structure development GO:0048608 43 43 2,000 7,27E-03 0,06007984 ! negative regulation of organelle organization GO:0010639 45 44 2,000 7,75E-03 0,06376701 ! positive regulation of cell differentiation GO:0045597 87 85 3,000 7,854E-03 0,06433064 ! positive regulation of response to stimulus GO:0048584 86 85 3,000 7,854E-03 0,064046 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 3,000 8,18E-03 0,06641489 ! regulation of DNA binding GO:0051101 47 45 2,000 8,249E-03 0,06668301 ! Wnt receptor signaling pathway GO:0016055 46 45 2,000 8,249E-03 0,06639181 ! protein processing GO:0016485 45 45 2,000 8,249E-03 0,06610315 ! negative regulation of protein complex assembly GO:0031333 15 15 1,000 8,274E-03 0,06601033 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 8,274E-03 0,06572581 ! striated muscle cell differentiation GO:0051146 16 15 1,000 8,274E-03 0,06544372 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 8,274E-03 0,06516405 ! response to starvation GO:0042594 15 15 1,000 8,274E-03 0,06488675 ! negative regulation of transcription factor activity GO:0043433 16 15 1,000 8,274E-03 0,06461181 GO:0090048|negative regulation of transcription regulator activity, ! male gamete generation GO:0048232 90 88 3,000 8,86E-03 0,06889728 GO:0007283|spermatogenesis, ! positive regulation of transferase activity GO:0051347 91 88 3,000 8,86E-03 0,0686078 GO:0033674|positive regulation of kinase activity, ! regulation of catabolic process GO:0009894 48 47 2,000 9,304E-03 0,0717423 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 1,000 9,399E-03 0,07217872 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of mitosis GO:0045840 16 16 1,000 9,399E-03 0,07187923 GO:0051785|positive regulation of nuclear division, ! vesicle targeting GO:0006903 17 16 1,000 9,399E-03 0,07158221 ! segmentation GO:0035282 17 16 1,000 9,399E-03 0,07128763 ! triglyceride metabolic process GO:0006641 16 16 1,000 9,399E-03 0,07099547 ! iron ion homeostasis GO:0055072 16 16 1,000 9,399E-03 0,07070569 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 1,000 9,399E-03 0,07041827 ! serine family amino acid metabolic process GO:0009069 16 16 1,000 9,399E-03 0,07013317 ! positive regulation of catabolic process GO:0009896 16 16 1,000 9,399E-03 0,06985038 ! regulation of cell cycle process GO:0010564 50 48 2,000 9,859E-03 0,0729707 ! DNA replication GO:0006260 91 91 3,000 9,947E-03 0,07332882 ! gland development GO:0048732 51 49 2,000 0,01043297 0,0766054 ! skeletal muscle tissue development GO:0007519 50 49 2,000 0,01043297 0,07630141 GO:0060538|skeletal muscle organ development, ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 0,0105891 0,07713721 ! regulation of transmembrane transport GO:0034762 17 17 1,000 0,0105891 0,07683352 ! neural crest cell development GO:0014032 19 17 1,000 0,0105891 0,07653221 GO:0014033|neural crest cell differentiation, ! immune response-activating signal transduction GO:0002757 17 17 1,000 0,0105891 0,07623325 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 1,000 0,0105891 0,07593663 ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 0,0105891 0,0756423 ! pigmentation GO:0043473 17 17 1,000 0,0105891 0,07535024 ! myeloid leukocyte activation GO:0002274 18 17 1,000 0,0105891 0,07506044 ! embryonic organ development GO:0048568 17 17 1,000 0,0105891 0,07477285 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 2,000 0,01102625 0,07756254 ! protein maturation GO:0051604 51 51 2,000 0,01163874 0,08155971 ! regulation of cell projection organization GO:0031344 19 18 1,000 0,01184185 0,0826687 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 0,01184185 0,08235674 ! neutral lipid metabolic process GO:0006638 18 18 1,000 0,01184185 0,08204713 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 1,000 0,01184185 0,08173983 ! negative regulation of catabolic process GO:0009895 18 18 1,000 0,01184185 0,08143483 ! establishment of vesicle localization GO:0051650 19 18 1,000 0,01184185 0,0811321 ! regulation of cell growth GO:0001558 97 96 3,000 0,01194531 0,08153779 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 2,000 0,01227054 0,08344872 ! posttranscriptional regulation of gene expression GO:0010608 98 98 3,000 0,01281188 0,0868099 ! glycoprotein metabolic process GO:0009100 99 98 3,000 0,01281188 0,08649191 ! DNA damage checkpoint GO:0000077 19 19 1,000 0,01315631 0,08849301 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 0,01315631 0,08817121 ! multicellular organismal metabolic process GO:0044236 19 19 1,000 0,01315631 0,08785175 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 0,01315631 0,0875346 ! hormone biosynthetic process GO:0042446 19 19 1,000 0,01315631 0,08721972 ! regulation of cell shape GO:0008360 21 19 1,000 0,01315631 0,08690711 ! placenta development GO:0001890 19 19 1,000 0,01315631 0,08659673 ! vesicle localization GO:0051648 20 19 1,000 0,01315631 0,08628855 ! hormone metabolic process GO:0042445 55 54 2,000 0,01359242 0,08883274 ! muscle organ development GO:0007517 102 100 3,000 0,0137178 0,08933535 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 2,000 0,01428268 0,09268655 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! negative regulation of cell adhesion GO:0007162 21 20 1,000 0,01453126 0,09396881 ! establishment or maintenance of cell polarity GO:0007163 21 20 1,000 0,01453126 0,09364024 ! organic ether metabolic process GO:0018904 20 20 1,000 0,01453126 0,09331397 GO:0006662|glycerol ether metabolic process, ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 0,01453126 0,09298996 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 0,01453126 0,0926682 ! RNA modification GO:0009451 20 20 1,000 0,01453126 0,09234865 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 2,000 0,01499258 0,09495303 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 2,000 0,0157222 0,09923292 ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 0,01596549 0,10042457 ! DNA integrity checkpoint GO:0031570 21 21 1,000 0,01596549 0,10008299 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 0,01596549 0,09974372 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 0,01596549 0,09940675 ! negative regulation of protein transport GO:0051224 21 21 1,000 0,01596549 0,09907205 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 0,0172408 0,10662681 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 0,01745782 0,1076079 GO:0090047|positive regulation of transcription regulator activity, ! sister chromatid segregation GO:0000819 22 22 1,000 0,01745782 0,10724921 ! maintenance of protein location in cell GO:0032507 23 22 1,000 0,01745782 0,1068929 ! spindle organization GO:0007051 22 22 1,000 0,01745782 0,10653895 ! erythrocyte differentiation GO:0030218 23 22 1,000 0,01745782 0,10618733 ! biopolymer methylation GO:0043414 22 22 1,000 0,01745782 0,10583803 GO:0032259|methylation, ! epithelial cell differentiation GO:0030855 23 23 1,000 0,01900708 0,11485262 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 2,000 0,01966779 0,11845669 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 2,000 0,02051669 0,12316698 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 2,000 0,02051669 0,12276709 ! cellular amino acid biosynthetic process GO:0008652 24 24 1,000 0,02061212 0,12293893 ! heterocycle biosynthetic process GO:0018130 24 24 1,000 0,02061212 0,12254235 ! T cell differentiation GO:0030217 24 24 1,000 0,02061212 0,12214832 ! erythrocyte homeostasis GO:0034101 25 24 1,000 0,02061212 0,12175682 ! maintenance of protein location GO:0045185 25 24 1,000 0,02061212 0,12136782 ! regulation of response to external stimulus GO:0032101 65 64 2,000 0,02138558 0,12552108 ! angiogenesis GO:0001525 65 64 2,000 0,02138558 0,1251226 ! regulation of gene-specific transcription GO:0032583 25 25 1,000 0,02227179 0,12989528 ! endosome transport GO:0016197 25 25 1,000 0,02227179 0,12948551 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 0,02227179 0,12907833 ! positive regulation of DNA binding GO:0043388 26 25 1,000 0,02227179 0,12867369 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 1,000 0,02227179 0,12827159 ! heart morphogenesis GO:0003007 25 25 1,000 0,02227179 0,12787199 ! icosanoid metabolic process GO:0006690 25 25 1,000 0,02227179 0,12747487 ! regulation of endocytosis GO:0030100 25 25 1,000 0,02227179 0,12708021 ! positive regulation of cytokine production GO:0001819 25 25 1,000 0,02227179 0,12668799 ! regulation of hormone levels GO:0010817 66 65 2,000 0,02227446 0,12631334 ! nucleoside triphosphate metabolic process GO:0009141 66 66 2,000 0,02318336 0,1310642 ! negative regulation of protein metabolic process GO:0051248 66 66 2,000 0,02318336 0,1306634 ! positive regulation of binding GO:0051099 27 26 1,000 0,02398498 0,13476926 ! positive regulation of defense response GO:0031349 26 26 1,000 0,02398498 0,13435963 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 1,000 0,02398498 0,13395248 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 1,000 0,02398498 0,13354779 ! negative regulation of cell migration GO:0030336 26 26 1,000 0,02398498 0,13314554 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 0,02398498 0,1327457 ! germ cell development GO:0007281 27 26 1,000 0,02398498 0,13234826 ! response to insulin stimulus GO:0032868 28 26 1,000 0,02398498 0,13195319 ! maintenance of location in cell GO:0051651 27 26 1,000 0,02398498 0,13156047 ! synapse organization GO:0050808 26 26 1,000 0,02398498 0,13117009 ! response to radiation GO:0009314 70 68 2,000 0,02506118 0,13665019 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 2,000 0,02506118 0,13624709 ! regulation of cell size GO:0008361 68 68 2,000 0,02506118 0,13584636 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 0,02575058 0,13917396 ! regulation of neurotransmitter levels GO:0001505 31 27 1,000 0,02575058 0,13876702 ! cAMP-mediated signaling GO:0019933 27 27 1,000 0,02575058 0,13836245 ! mesenchymal cell development GO:0014031 29 27 1,000 0,02575058 0,13796024 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! cell growth GO:0016049 27 27 1,000 0,02575058 0,13756035 ! regionalization GO:0003002 70 69 2,000 0,0260301 0,13865167 ! response to nutrient levels GO:0031667 69 69 2,000 0,0260301 0,1382521 ! wound healing GO:0042060 74 70 2,000 0,027019 0,14309203 ! unsaturated fatty acid metabolic process GO:0033559 28 28 1,000 0,0275675 0,14557853 ! keratinocyte differentiation GO:0030216 28 28 1,000 0,0275675 0,14516259 ! histone modification GO:0016570 28 28 1,000 0,0275675 0,14474902 ! cartilage development GO:0051216 29 28 1,000 0,0275675 0,14433781 ! ribosome biogenesis GO:0042254 71 71 2,000 0,02802788 0,1463325 ! response to extracellular stimulus GO:0009991 72 72 2,000 0,02905669 0,15127536 ! positive regulation of cell cycle GO:0045787 29 29 1,000 0,02943467 0,15281153 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 0,02943467 0,15238228 ! DNA-dependent DNA replication GO:0006261 29 29 1,000 0,02943467 0,15195544 ! tRNA processing GO:0008033 29 29 1,000 0,02943467 0,15153099 ! regulation of gene expression, epigenetic GO:0040029 29 29 1,000 0,02943467 0,1511089 ! covalent chromatin modification GO:0016569 29 29 1,000 0,02943467 0,15068915 ! positive regulation of protein transport GO:0051222 29 29 1,000 0,02943467 0,15027173 ! response to UV GO:0009411 29 29 1,000 0,02943467 0,14985661 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 1,000 0,03135102 0,15917334 ! response to temperature stimulus GO:0009266 30 30 1,000 0,03135102 0,15873606 ! vascular process in circulatory system GO:0003018 31 30 1,000 0,03135102 0,15830116 ! regulation of inflammatory response GO:0050727 30 30 1,000 0,03135102 0,15786865 ! ribonucleotide biosynthetic process GO:0009260 75 75 2,000 0,03226246 0,16201558 ! purine ribonucleotide metabolic process GO:0009150 75 75 2,000 0,03226246 0,16157532 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,0333155 0,16639695 ! digestion GO:0007586 31 31 1,000 0,0333155 0,16594722 ! regulation of DNA replication GO:0006275 32 31 1,000 0,0333155 0,16549993 ! regulation of intracellular transport GO:0032386 31 31 1,000 0,0333155 0,16505504 ! epidermal cell differentiation GO:0009913 31 31 1,000 0,0333155 0,16461253 ! negative regulation of cell growth GO:0030308 32 32 1,000 0,0353271 0,17408513 ! muscle fiber development GO:0048747 32 32 1,000 0,0353271 0,17362091 ! cell maturation GO:0048469 32 32 1,000 0,0353271 0,17315915 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 0,0353271 0,17269984 ! maintenance of location GO:0051235 33 32 1,000 0,0353271 0,17224296 ! positive regulation of protein kinase cascade GO:0010740 79 78 2,000 0,03564638 0,17334109 ! negative regulation of cell size GO:0045792 33 33 1,000 0,03738478 0,18131619 ! regulation of protein complex assembly GO:0043254 33 33 1,000 0,03738478 0,18084029 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 1,000 0,03738478 0,18036689 ! regulation of actin filament length GO:0030832 34 34 1,000 0,03948755 0,19001451 ! regulation of angiogenesis GO:0045765 35 34 1,000 0,03948755 0,18951968 ! regulation of bone remodeling GO:0046850 34 34 1,000 0,03948755 0,18902743 ! response to metal ion GO:0010038 34 34 1,000 0,03948755 0,18853772 ! muscle cell differentiation GO:0042692 35 34 1,000 0,03948755 0,18805054 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,03948755 0,18756587 ! coenzyme biosynthetic process GO:0009108 34 34 1,000 0,03948755 0,1870837 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 0,03948755 0,186604 ! regulation of cellular component size GO:0032535 35 35 1,000 0,04163442 0,19624614 ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,04163442 0,19574552 ! regulation of tissue remodeling GO:0034103 35 35 1,000 0,04163442 0,19524744 ! ribonucleotide metabolic process GO:0009259 83 83 2,000 0,04167811 0,19495622 ! blood vessel morphogenesis GO:0048514 84 83 2,000 0,04167811 0,19446266 ! response to inorganic substance GO:0010035 36 36 1,000 0,04382442 0,20396062 ! embryonic limb morphogenesis GO:0030326 36 36 1,000 0,04382442 0,20344687 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,04382442 0,2029357 ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 0,04382442 0,20242708 ! activation of immune response GO:0002253 36 36 1,000 0,04382442 0,20192102 ! coagulation GO:0050817 39 36 1,000 0,04382442 0,20141747 GO:0007596|blood coagulation, ! regulation of cellular localization GO:0060341 86 85 2,000 0,04422637 0,20275922 ! nitrogen compound biosynthetic process GO:0044271 86 85 2,000 0,04422637 0,2022561 ! positive regulation of protein kinase activity GO:0045860 89 86 2,000 0,04552925 0,20769901 ! rRNA transcription GO:0009303 5 5 0,000 0,04566734 0,20781458 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,04566734 0,20730272 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,04566734 0,20679338 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,04566734 0,20628653 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,04566734 0,20578216 ! reproductive cellular process GO:0048610 5 5 0,000 0,04566734 0,20528025 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,04566734 0,20478079 ! metencephalon development GO:0022037 5 5 0,000 0,04566734 0,20428375 ! water transport GO:0006833 5 5 0,000 0,04566734 0,20378911 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,04566734 0,20329687 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,04566734 0,202807 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,04566734 0,20231948 ! glycerol metabolic process GO:0006071 5 5 0,000 0,04566734 0,2018343 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,04566734 0,20135144 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,04566734 0,20087089 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,04566734 0,20039263 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,04566734 0,19991664 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,04566734 0,1994429 ! Golgi to endosome transport GO:0006895 5 5 0,000 0,04566734 0,1989714 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,04566734 0,19850213 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,04566734 0,19803507 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,04566734 0,1975702 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,04566734 0,1971075 ! social behavior GO:0035176 5 5 0,000 0,04566734 0,19664697 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,04566734 0,19618859 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,04566734 0,19573233 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,04566734 0,1952782 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,04566734 0,19482617 ! response to lipid GO:0033993 5 5 0,000 0,04566734 0,19437622 ! erythrocyte maturation GO:0043249 5 5 0,000 0,04566734 0,19392835 ! hippocampus development GO:0021766 6 5 0,000 0,04566734 0,19348254 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,04566734 0,19303877 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,04566734 0,19259703 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,04566734 0,19215731 ! mechanosensory behavior GO:0007638 5 5 0,000 0,04566734 0,1917196 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,04566734 0,19128387 ! response to interferon-gamma GO:0034341 5 5 0,000 0,04566734 0,19085012 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,04566734 0,19041833 ! endocrine pancreas development GO:0031018 5 5 0,000 0,04566734 0,1899885 ! pH reduction GO:0045851 5 5 0,000 0,04566734 0,18956059 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,04566734 0,18913461 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,04566734 0,18871055 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,04566734 0,18828838 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,04566734 0,18786809 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,04566734 0,18744967 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,04566734 0,18703312 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,04566734 0,18661841 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,04566734 0,18620554 ! adrenal gland development GO:0030325 5 5 0,000 0,04566734 0,18579449 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,04566734 0,18538525 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,04566734 0,18497781 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,04566734 0,18457216 ! astrocyte differentiation GO:0048708 5 5 0,000 0,04566734 0,18416828 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,04566734 0,18376617 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,04566734 0,1833658 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,04566734 0,18296718 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,04566734 0,18257029 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,04566734 0,18217512 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,04566734 0,18178165 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,04566734 0,18138988 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,04566734 0,18099979 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,04566734 0,18061138 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,04566734 0,18022463 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,04566734 0,17983954 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,04566734 0,17945608 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,04566734 0,17907426 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,04566734 0,17869406 ! response to ATP GO:0033198 5 5 0,000 0,04566734 0,17831547 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,04566734 0,17793849 ! regulation of appetite GO:0032098 5 5 0,000 0,04566734 0,17756309 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,04566734 0,17718927 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,04566734 0,17681702 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,04566734 0,17644634 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,04566734 0,1760772 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,04566734 0,17570961 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,04566734 0,17534355 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,04566734 0,17497901 ! fear response GO:0042596 5 5 0,000 0,04566734 0,17461598 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,04566734 0,17425446 ! retinol metabolic process GO:0042572 5 5 0,000 0,04566734 0,17389443 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,04566734 0,17353588 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,04566734 0,17317881 ! parturition GO:0007567 5 5 0,000 0,04566734 0,17282321 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,04566734 0,17246906 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,04566734 0,17211637 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,04566734 0,17176511 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,04566734 0,17141528 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,04566734 0,17106688 ! response to UV-B GO:0010224 5 5 0,000 0,04566734 0,17071989 ! oligodendrocyte development GO:0014003 5 5 0,000 0,04566734 0,1703743 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,04566734 0,17003011 ! activated T cell proliferation GO:0050798 5 5 0,000 0,04566734 0,16968731 ! interaction with symbiont GO:0051702 5 5 0,000 0,04566734 0,16934588 ! cellular extravasation GO:0045123 5 5 0,000 0,04566734 0,16900583 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,04566734 0,16866714 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,04566734 0,16832981 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,04566734 0,16799382 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,04566734 0,16765917 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,04566734 0,16732585 ! response to amine stimulus GO:0014075 5 5 0,000 0,04566734 0,16699386 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,04566734 0,16666318 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,04566734 0,1663338 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,04566734 0,16600573 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,04566734 0,16567894 ! neuron recognition GO:0008038 5 5 0,000 0,04566734 0,16535345 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,04566734 0,16502922 ! decidualization GO:0046697 5 5 0,000 0,04566734 0,16470627 ! hair follicle maturation GO:0048820 5 5 0,000 0,04566734 0,16438458 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,04566734 0,16406414 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,04566734 0,16374495 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,04566734 0,163427 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,04566734 0,16311028 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,04566734 0,16279478 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,04566734 0,16248051 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,04566734 0,16216744 ! histone methylation GO:0016571 5 5 0,000 0,04566734 0,16185558 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,04566734 0,16154492 ! T cell lineage commitment GO:0002360 5 5 0,000 0,04566734 0,16123545 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,04566734 0,16092716 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,04566734 0,16062005 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,04566734 0,1603141 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,04566734 0,16000932 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,04566734 0,1597057 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,04566734 0,15940323 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,04566734 0,1591019 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,04566734 0,15880171 ! sterol catabolic process GO:0016127 5 5 0,000 0,04566734 0,15850264 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,04566734 0,15820471 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,04566734 0,15790789 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,04566734 0,15761218 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,04566734 0,15731758 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,04566734 0,15702407 ! zymogen activation GO:0031638 5 5 0,000 0,04566734 0,15673166 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,04566734 0,15644034 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,04566734 0,1561501 GO:0002820|negative regulation of adaptive immune response, ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,04566734 0,15586093 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,04566734 0,15557283 ! nucleosome positioning GO:0016584 5 5 0,000 0,04566734 0,1552858 ! regulation of isotype switching GO:0045191 5 5 0,000 0,04566734 0,15499982 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,04566734 0,1547149 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,04566734 0,15443102 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,04566734 0,15414818 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,04566734 0,15386637 ! NADPH regeneration GO:0006740 5 5 0,000 0,04566734 0,15358559 GO:0006098|pentose-phosphate shunt, ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,04566734 0,15330584 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,04566734 0,1530271 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,04566734 0,15274937 ! sarcomere organization GO:0045214 5 5 0,000 0,04566734 0,15247265 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,04566734 0,15219693 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,04566734 0,15192221 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,04566734 0,15164848 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,04566734 0,15137573 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,04566734 0,15110396 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,04566734 0,15083316 ! spleen development GO:0048536 5 5 0,000 0,04566734 0,15056333 ! male genitalia development GO:0030539 5 5 0,000 0,04566734 0,15029447 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,04566734 0,15002657 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,04566734 0,14975962 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,04566734 0,14949361 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,04566734 0,14922855 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,04566734 0,14896443 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,04566734 0,14870124 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,04566734 0,14843898 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,04566734 0,14817765 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,04566734 0,14791723 ! ATP catabolic process GO:0006200 5 5 0,000 0,04566734 0,14765773 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,04566734 0,14739913 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,04566734 0,14714144 ! blastocyst formation GO:0001825 5 5 0,000 0,04566734 0,14688465 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,04566734 0,14662875 ! embryonic gut development GO:0048566 5 5 0,000 0,04566734 0,14637375 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,04566734 0,14611962 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,04566734 0,14586638 ! activation of innate immune response GO:0002218 5 5 0,000 0,04566734 0,14561402 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,04566734 0,14536253 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,04566734 0,1451119 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,04566734 0,14486214 ! muscle adaptation GO:0043500 5 5 0,000 0,04566734 0,14461324 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,04566734 0,14436519 ! embryonic heart tube development GO:0035050 5 5 0,000 0,04566734 0,14411799 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,04566734 0,14387163 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,04566734 0,14362612 ! defense response to fungus GO:0050832 5 5 0,000 0,04566734 0,14338144 ! lysogeny GO:0030069 5 5 0,000 0,04566734 0,14313759 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,04566734 0,14289457 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,04566734 0,14265238 ! response to nicotine GO:0035094 5 5 0,000 0,04566734 0,142411 ! establishment of cell polarity GO:0030010 5 5 0,000 0,04566734 0,14217045 ! mitochondrion localization GO:0051646 5 5 0,000 0,04566734 0,1419307 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,04566734 0,14169176 ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 0,04605658 0,1426593 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 0,04605658 0,14241994 ! response to drug GO:0042493 37 37 1,000 0,04605658 0,14218138 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,04605658 0,14194361 ! ATP synthesis coupled electron transport GO:0042773 37 37 1,000 0,04605658 0,14170665 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! adaptive immune response GO:0002250 37 37 1,000 0,04605658 0,14147047 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! heart development GO:0007507 90 87 2,000 0,04685116 0,1436717 ! purine nucleotide biosynthetic process GO:0006164 88 88 2,000 0,04819203 0,14753807 ! positive regulation of secretion GO:0051047 39 38 1,000 0,04832996 0,14771496 ! neurotransmitter transport GO:0006836 40 38 1,000 0,04832996 0,1474704 ! cellular hormone metabolic process GO:0034754 39 38 1,000 0,04832996 0,14722665 ! exocytosis GO:0006887 40 38 1,000 0,04832996 0,1469837 ! negative regulation of kinase activity GO:0033673 38 38 1,000 0,04832996 0,14674155 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 2,000 0,04955177 0,15020379 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 0,05064363 0,15326143 ! hemostasis GO:0007599 42 39 1,000 0,05064363 0,15301018 ! intracellular protein transmembrane transport GO:0065002 39 39 1,000 0,05064363 0,15275975 ! developmental maturation GO:0021700 39 39 1,000 0,05064363 0,15251014 ! lymphocyte differentiation GO:0030098 39 39 1,000 0,05064363 0,15226135 ! limb development GO:0060173 39 39 1,000 0,05064363 0,15201337 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 1,000 0,05064363 0,15176619 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 2,000 0,05232742 0,15655752 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 0,05299666 0,15830283 ! negative regulation of transferase activity GO:0051348 40 40 1,000 0,05299666 0,15804668 ! positive regulation of immune system process GO:0002684 92 92 2,000 0,05374314 0,1600139 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,05455131 0,16215816 ! axon extension GO:0048675 7 6 0,000 0,05455131 0,16189704 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,05455131 0,16163675 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,05455131 0,1613773 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,05455131 0,16111869 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,05455131 0,1608609 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,05455131 0,16060393 ! virus-host interaction GO:0019048 6 6 0,000 0,05455131 0,16034778 ! regulation of S phase GO:0033261 6 6 0,000 0,05455131 0,16009245 ! myotube differentiation GO:0014902 6 6 0,000 0,05455131 0,15983793 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,05455131 0,15958422 ! bone remodeling GO:0046849 6 6 0,000 0,05455131 0,15933131 ! N-glycan processing GO:0006491 6 6 0,000 0,05455131 0,15907921 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,05455131 0,1588279 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,05455131 0,15857738 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,05455131 0,15832765 ! RNA methylation GO:0001510 6 6 0,000 0,05455131 0,15807871 ! cartilage condensation GO:0001502 7 6 0,000 0,05455131 0,15783055 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,05455131 0,15758317 ! succinate metabolic process GO:0006105 7 6 0,000 0,05455131 0,15733656 ! artery development GO:0060840 6 6 0,000 0,05455131 0,15709072 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,05455131 0,15684565 ! bile acid metabolic process GO:0008206 6 6 0,000 0,05455131 0,15660134 ! androgen metabolic process GO:0008209 6 6 0,000 0,05455131 0,15635779 ! estrogen metabolic process GO:0008210 6 6 0,000 0,05455131 0,156115 ! limbic system development GO:0021761 7 6 0,000 0,05455131 0,15587296 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,05455131 0,15563167 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,05455131 0,15539113 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,05455131 0,15515133 ! pathogenesis GO:0009405 6 6 0,000 0,05455131 0,15491226 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,05455131 0,15467394 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,05455131 0,15443634 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,05455131 0,15419948 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,05455131 0,15396334 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,05455131 0,15372792 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,05455131 0,15349322 ! arginine metabolic process GO:0006525 6 6 0,000 0,05455131 0,15325924 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,05455131 0,15302597 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,05455131 0,1527934 ! glutamate catabolic process GO:0006538 7 6 0,000 0,05455131 0,15256155 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,05455131 0,15233039 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,05455131 0,15209994 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,05455131 0,15187018 GO:0005978|glycogen biosynthetic process, ! ER overload response GO:0006983 6 6 0,000 0,05455131 0,15164112 ! V(D)J recombination GO:0033151 6 6 0,000 0,05455131 0,15141274 ! focal adhesion formation GO:0048041 7 6 0,000 0,05455131 0,15118505 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,05455131 0,15095805 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 0,05455131 0,15073172 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,05455131 0,15050608 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,05455131 0,15028111 ! regulation of heart rate GO:0002027 6 6 0,000 0,05455131 0,15005681 ! lipid digestion GO:0044241 6 6 0,000 0,05455131 0,14983317 ! asymmetric protein localization GO:0008105 6 6 0,000 0,05455131 0,14961021 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,05455131 0,1493879 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,05455131 0,14916626 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,05455131 0,14894527 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,05455131 0,14872494 ! ruffle organization GO:0031529 6 6 0,000 0,05455131 0,14850526 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,05455131 0,14828622 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,05455131 0,14806783 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,05455131 0,14785009 ! neutral amino acid transport GO:0015804 6 6 0,000 0,05455131 0,14763298 ! L-amino acid transport GO:0015807 6 6 0,000 0,05455131 0,14741651 ! bone mineralization GO:0030282 6 6 0,000 0,05455131 0,14720067 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,05455131 0,14698547 ! negative regulation of ossification GO:0030279 6 6 0,000 0,05455131 0,14677089 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,05455131 0,14655694 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,05455131 0,14634361 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,05455131 0,1461309 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,05455131 0,14591881 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,05455131 0,14570733 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,05455131 0,14549647 ! regulation of organ growth GO:0046620 6 6 0,000 0,05455131 0,14528621 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,05455131 0,14507656 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,05455131 0,14486752 ! response to dsRNA GO:0043331 6 6 0,000 0,05455131 0,14465908 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,05455131 0,14445123 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 0,05455131 0,14424399 ! genitalia development GO:0048806 6 6 0,000 0,05455131 0,14403733 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,05455131 0,14383127 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,05455131 0,1436258 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 0,05455131 0,14342091 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,05455131 0,14321661 ! multicellular organismal aging GO:0010259 6 6 0,000 0,05455131 0,14301289 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,05455131 0,14280974 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,05455131 0,14260718 ! erythrocyte development GO:0048821 6 6 0,000 0,05455131 0,14240518 ! renal water homeostasis GO:0003091 6 6 0,000 0,05455131 0,14220376 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,05455131 0,14200291 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,05455131 0,14180262 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,05455131 0,1416029 ! ribosome assembly GO:0042255 6 6 0,000 0,05455131 0,14140374 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,05455131 0,14120514 ! diencephalon development GO:0021536 6 6 0,000 0,05455131 0,1410071 ! fucose catabolic process GO:0019317 6 6 0,000 0,05455131 0,14080961 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,05455131 0,14061267 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,05455131 0,14041628 ! regulation of lipid transport GO:0032368 6 6 0,000 0,05455131 0,14022045 ! regulation of cell division GO:0051302 6 6 0,000 0,05455131 0,14002515 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,05455131 0,1398304 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,05455131 0,13963619 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,05455131 0,13944252 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,05455131 0,13924939 ! neuroblast proliferation GO:0007405 6 6 0,000 0,05455131 0,13905679 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,05455131 0,13886472 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,05455131 0,13867319 ! regulation of glucose transport GO:0010827 6 6 0,000 0,05455131 0,13848218 GO:0046324|regulation of glucose import, ! methionine biosynthetic process GO:0009086 6 6 0,000 0,05455131 0,13829169 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,05455131 0,13810173 ! thymus development GO:0048538 6 6 0,000 0,05455131 0,13791229 ! lymph node development GO:0048535 6 6 0,000 0,05455131 0,13772337 ! organic cation transport GO:0015695 6 6 0,000 0,05455131 0,13753497 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,05455131 0,13734708 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,05455131 0,1371597 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,05455131 0,13697283 ! sperm-egg recognition GO:0035036 7 6 0,000 0,05455131 0,13678648 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,05455131 0,13660062 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,05455131 0,13641528 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,05455131 0,13623043 ! alditol metabolic process GO:0019400 6 6 0,000 0,05455131 0,13604609 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,05455131 0,13586224 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,05455131 0,13567889 ! maternal placenta development GO:0001893 6 6 0,000 0,05455131 0,13549604 ! regulation of embryonic development GO:0045995 6 6 0,000 0,05455131 0,13531367 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,05455131 0,1351318 ! localization within membrane GO:0051668 6 6 0,000 0,05455131 0,13495042 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,05538815 0,13683695 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! blood vessel development GO:0001568 95 94 2,000 0,05662984 0,13971725 ! pattern specification process GO:0007389 96 94 2,000 0,05662984 0,13953047 ! respiratory electron transport chain GO:0022904 43 42 1,000 0,05781721 0,14226583 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,05781721 0,14207615 ! one-carbon metabolic process GO:0006730 42 42 1,000 0,05781721 0,14188696 ! vasculature development GO:0001944 97 96 2,000 0,05958948 0,14604176 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 1,000 0,06028294 0,14754511 ! homeostasis of number of cells GO:0048872 44 43 1,000 0,06028294 0,14734942 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,06028294 0,14715426 ! blood circulation GO:0008015 99 98 2,000 0,06262113 0,15265972 GO:0003013|circulatory system process, ! respiratory burst GO:0045730 7 7 0,000 0,06335386 0,15424195 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,06335386 0,15403846 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,06335386 0,15383551 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,06335386 0,1536331 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,06335386 0,15343122 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,06335386 0,15322986 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,06335386 0,15302904 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,06335386 0,15282874 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,06335386 0,15262896 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,06335386 0,15242971 ! gene silencing by RNA GO:0031047 7 7 0,000 0,06335386 0,15223097 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,06335386 0,15203275 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,06335386 0,15183505 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,06335386 0,15163786 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,06335386 0,15144119 ! axis specification GO:0009798 7 7 0,000 0,06335386 0,15124502 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,06335386 0,15104936 ! visual behavior GO:0007632 7 7 0,000 0,06335386 0,15085421 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,06335386 0,15065956 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,06335386 0,15046541 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,06335386 0,15027176 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,06335386 0,15007861 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,06335386 0,14988595 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,06335386 0,14969379 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,06335386 0,14950212 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,06335386 0,14931094 ! digestive system development GO:0055123 7 7 0,000 0,06335386 0,14912025 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,06335386 0,14893005 ! protein targeting to ER GO:0045047 8 7 0,000 0,06335386 0,14874033 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,06335386 0,14855109 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,06335386 0,14836233 ! endoderm development GO:0007492 7 7 0,000 0,06335386 0,14817406 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,06335386 0,14798626 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,06335386 0,14779893 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,06335386 0,14761208 ! response to hexose stimulus GO:0009746 7 7 0,000 0,06335386 0,1474257 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,06335386 0,14723979 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,06335386 0,14705435 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 0,06335386 0,14686938 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,06335386 0,14668487 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,06335386 0,14650082 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,06335386 0,14631724 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,06335386 0,14613411 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,06335386 0,14595144 ! response to X-ray GO:0010165 7 7 0,000 0,06335386 0,14576923 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,06335386 0,14558748 ! UV protection GO:0009650 7 7 0,000 0,06335386 0,14540617 ! DNA integration GO:0015074 7 7 0,000 0,06335386 0,14522532 ! myofibril assembly GO:0030239 7 7 0,000 0,06335386 0,14504491 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,06335386 0,14486496 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,06335386 0,14468545 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,06335386 0,14450638 GO:0030204|chondroitin sulfate metabolic process, ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,06335386 0,14432776 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,06335386 0,14414958 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,06335386 0,14397183 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,06335386 0,14379453 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,06335386 0,14361766 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,06335386 0,14344122 ! axon cargo transport GO:0008088 7 7 0,000 0,06335386 0,14326522 ! eating behavior GO:0042755 7 7 0,000 0,06335386 0,14308965 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,06335386 0,14291451 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,06335386 0,1427398 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,06335386 0,14256551 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,06335386 0,14239165 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,06335386 0,14221822 ! cranial nerve development GO:0021545 7 7 0,000 0,06335386 0,1420452 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,06335386 0,14187261 ! induction of an organ GO:0001759 7 7 0,000 0,06335386 0,14170043 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,06335386 0,14152867 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,06335386 0,14135733 ! autonomic nervous system development GO:0048483 7 7 0,000 0,06335386 0,1411864 ! intracellular lipid transport GO:0032365 7 7 0,000 0,06335386 0,14101589 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,06335386 0,14084579 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,06335386 0,14067609 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,06335386 0,14050681 ! natural killer cell activation GO:0030101 7 7 0,000 0,06335386 0,14033793 ! response to gamma radiation GO:0010332 8 7 0,000 0,06335386 0,14016945 ! NADP metabolic process GO:0006739 7 7 0,000 0,06335386 0,14000139 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,06335386 0,13983372 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,06335386 0,13966645 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,06335386 0,13949959 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,06335386 0,13933312 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,06335386 0,13916705 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,06335386 0,13900138 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,06335386 0,13883609 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,06335386 0,13867121 ! cell-cell recognition GO:0009988 8 7 0,000 0,06335386 0,13850671 ! hormone catabolic process GO:0042447 7 7 0,000 0,06335386 0,1383426 ! dopamine metabolic process GO:0042417 7 7 0,000 0,06335386 0,13817888 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,06335386 0,13801555 ! oxygen transport GO:0015671 7 7 0,000 0,06335386 0,1378526 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,06335386 0,13769004 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,06335386 0,13752786 ! regulation of axon extension GO:0030516 7 7 0,000 0,06335386 0,13736607 ! cell killing GO:0001906 7 7 0,000 0,06335386 0,13720465 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,06335386 0,13704361 ! adult feeding behavior GO:0008343 7 7 0,000 0,06335386 0,13688295 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,06335386 0,13672266 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,06335386 0,13656276 ! negative regulation of T cell activation GO:0050868 7 7 0,000 0,06335386 0,13640322 ! amine biosynthetic process GO:0009309 46 45 1,000 0,06532101 0,14047448 ! regulation of actin cytoskeleton organization GO:0032956 46 45 1,000 0,06532101 0,14031075 ! steroid biosynthetic process GO:0006694 46 45 1,000 0,06532101 0,14014741 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 2,000 0,06572386 0,14084775 ! regulation of actin filament-based process GO:0032970 47 46 1,000 0,06789164 0,14532439 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 1,000 0,06789164 0,1451558 ! tube morphogenesis GO:0035239 47 46 1,000 0,06789164 0,1449876 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 0,06789164 0,14481979 ! sex differentiation GO:0007548 47 47 1,000 0,07049556 0,15020036 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,07207572 0,15338978 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,07207572 0,15321286 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,07207572 0,15303634 ! positive regulation of translation GO:0045727 8 8 0,000 0,07207572 0,15286024 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,07207572 0,15268454 ! superoxide anion generation GO:0042554 8 8 0,000 0,07207572 0,15250924 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,07207572 0,15233434 ! cGMP metabolic process GO:0046068 8 8 0,000 0,07207572 0,15215985 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,07207572 0,15198575 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,07207572 0,15181205 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,07207572 0,15163875 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,07207572 0,15146585 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,07207572 0,15129333 ! zinc ion transport GO:0006829 8 8 0,000 0,07207572 0,15112121 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,07207572 0,15094948 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,07207572 0,15077815 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,07207572 0,1506072 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,07207572 0,15043663 ! lipid localization GO:0010876 8 8 0,000 0,07207572 0,15026646 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,07207572 0,15009666 ! response to cAMP GO:0051591 8 8 0,000 0,07207572 0,14992725 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,07207572 0,14975823 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,07207572 0,14958958 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,07207572 0,14942131 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,07207572 0,14925342 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,07207572 0,14908591 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,07207572 0,14891877 ! sensory perception of taste GO:0050909 8 8 0,000 0,07207572 0,14875201 ! organelle fusion GO:0048284 8 8 0,000 0,07207572 0,14858562 ! pancreas development GO:0031016 8 8 0,000 0,07207572 0,1484196 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,07207572 0,14825396 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,07207572 0,14808868 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,07207572 0,14792377 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,07207572 0,14775923 ! sperm motility GO:0030317 8 8 0,000 0,07207572 0,14759505 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,07207572 0,14743124 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,07207572 0,14726779 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,07207572 0,1471047 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,07207572 0,14694198 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,07207572 0,14677961 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,07207572 0,1466176 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,07207572 0,14645595 ! Golgi organization GO:0007030 8 8 0,000 0,07207572 0,14629465 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,07207572 0,14613371 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,07207572 0,14597313 ! fructose metabolic process GO:0006000 8 8 0,000 0,07207572 0,14581289 ! mannose metabolic process GO:0006013 9 8 0,000 0,07207572 0,14565301 ! NAD metabolic process GO:0019674 8 8 0,000 0,07207572 0,14549348 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,07207572 0,1453343 ! plasma membrane fusion GO:0045026 8 8 0,000 0,07207572 0,14517546 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,07207572 0,14501697 ! response to fungus GO:0009620 8 8 0,000 0,07207572 0,14485883 ! stem cell differentiation GO:0048863 8 8 0,000 0,07207572 0,14470103 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,07207572 0,14454358 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,07207572 0,14438646 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,07207572 0,14422969 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,07207572 0,14407326 ! regulation of vasodilation GO:0042312 8 8 0,000 0,07207572 0,14391717 ! vasoconstriction GO:0042310 8 8 0,000 0,07207572 0,14376141 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,07207572 0,143606 ! muscle cell development GO:0055001 8 8 0,000 0,07207572 0,14345091 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,07207572 0,14329617 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,07207572 0,14314175 ! sensory perception of pain GO:0019233 8 8 0,000 0,07207572 0,14298767 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,07207572 0,14283392 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,07207572 0,1426805 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,07207572 0,14252741 ! chromatin silencing GO:0006342 8 8 0,000 0,07207572 0,14237465 ! tissue regeneration GO:0042246 8 8 0,000 0,07207572 0,14222221 ! salivary gland development GO:0007431 8 8 0,000 0,07207572 0,1420701 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,07207572 0,14191832 ! T cell homeostasis GO:0043029 8 8 0,000 0,07207572 0,14176686 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,07207572 0,14161572 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,07207572 0,14146491 ! water homeostasis GO:0030104 8 8 0,000 0,07207572 0,14131441 ! cofactor transport GO:0051181 8 8 0,000 0,07207572 0,14116424 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,07207572 0,14101438 ! acid secretion GO:0046717 8 8 0,000 0,07207572 0,14086484 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,07207572 0,14071562 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,07207572 0,14056672 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,07207572 0,14041813 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,07207572 0,14026985 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 0,07207572 0,14012188 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,07207572 0,13997423 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,07207572 0,13982689 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,07207572 0,13967986 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,07207572 0,13953314 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,07207572 0,13938672 ! developmental induction GO:0031128 8 8 0,000 0,07207572 0,13924061 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,07207572 0,13909481 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,07207572 0,13894932 ! actin filament polymerization GO:0030041 9 8 0,000 0,07207572 0,13880412 ! peptide hormone processing GO:0016486 8 8 0,000 0,07207572 0,13865923 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,07207572 0,13851465 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,07207572 0,13837036 ! calcium ion transport GO:0006816 48 48 1,000 0,07313194 0,140252 ! DNA recombination GO:0006310 48 48 1,000 0,07313194 0,1401062 ! cellular lipid catabolic process GO:0044242 50 49 1,000 0,07579998 0,14506684 ! divalent metal ion transport GO:0070838 49 49 1,000 0,07579998 0,14491636 ! response to nutrient GO:0007584 49 49 1,000 0,07579998 0,14476619 ! positive regulation of MAP kinase activity GO:0043406 50 49 1,000 0,07579998 0,14461632 ! cofactor biosynthetic process GO:0051188 49 49 1,000 0,07579998 0,14446677 ! regulation of defense response GO:0031347 50 50 1,000 0,07849889 0,14945604 ! regulation of DNA metabolic process GO:0051052 51 50 1,000 0,07849889 0,14930181 ! negative regulation of transport GO:0051051 51 50 1,000 0,07849889 0,14914789 ! T cell activation GO:0042110 51 50 1,000 0,07849889 0,14899429 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,07849889 0,148841 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,07849889 0,14868803 ! lactation GO:0007595 10 9 0,000 0,08071762 0,15273365 ! embryonic pattern specification GO:0009880 10 9 0,000 0,08071762 0,152577 ! positive regulation of cell size GO:0045793 9 9 0,000 0,08071762 0,15242067 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,08071762 0,15226466 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,08071762 0,15210897 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,08071762 0,1519536 ! viral genome replication GO:0019079 9 9 0,000 0,08071762 0,15179854 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,08071762 0,1516438 ! copper ion transport GO:0006825 9 9 0,000 0,08071762 0,15148938 ! lipid phosphorylation GO:0046834 9 9 0,000 0,08071762 0,15133527 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,08071762 0,15118148 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,08071762 0,15102799 ! RNA polyadenylation GO:0043631 9 9 0,000 0,08071762 0,15087482 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,08071762 0,15072196 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,08071762 0,15056941 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,08071762 0,15041716 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,08071762 0,15026522 ! phospholipid efflux GO:0033700 9 9 0,000 0,08071762 0,1501136 ! response to alkaloid GO:0043279 10 9 0,000 0,08071762 0,14996227 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,08071762 0,14981125 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,08071762 0,14966054 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,08071762 0,14951012 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,08071762 0,14936001 ! response to ethanol GO:0045471 9 9 0,000 0,08071762 0,1492102 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,08071762 0,14906069 ! methionine metabolic process GO:0006555 9 9 0,000 0,08071762 0,14891148 ! glutamine metabolic process GO:0006541 9 9 0,000 0,08071762 0,14876257 ! cerebral cortex development GO:0021987 9 9 0,000 0,08071762 0,14861396 ! response to osmotic stress GO:0006970 9 9 0,000 0,08071762 0,14846564 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,08071762 0,14831762 ! central nervous system neuron development GO:0021954 10 9 0,000 0,08071762 0,14816989 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,08071762 0,14802246 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,08071762 0,14787532 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,08071762 0,14772847 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,08071762 0,14758192 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,08071762 0,14743565 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,08071762 0,14728968 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,08071762 0,14714399 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,08071762 0,14699859 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,08071762 0,14685348 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,08071762 0,14670865 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,08071762 0,14656411 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,08071762 0,14641985 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,08071762 0,14627588 ! DNA replication initiation GO:0006270 9 9 0,000 0,08071762 0,14613219 ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,08071762 0,14598879 ! regulation of cellular pH GO:0030641 9 9 0,000 0,08071762 0,14584566 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,08071762 0,14570281 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,08071762 0,14556025 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,08071762 0,14541796 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,08071762 0,14527595 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,08071762 0,14513422 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,08071762 0,14499276 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,08071762 0,14485158 ! collagen catabolic process GO:0030574 9 9 0,000 0,08071762 0,14471067 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,08071762 0,14457004 ! purine base metabolic process GO:0006144 9 9 0,000 0,08071762 0,14442968 ! gas transport GO:0015669 9 9 0,000 0,08071762 0,1442896 ! cholesterol efflux GO:0033344 9 9 0,000 0,08071762 0,14414978 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,08071762 0,14401023 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,08071762 0,14387096 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,08071762 0,14373195 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,08071762 0,14359322 ! defense response to virus GO:0051607 9 9 0,000 0,08071762 0,14345475 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,08071762 0,14331654 ! actin filament-based movement GO:0030048 9 9 0,000 0,08071762 0,14317861 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,08071762 0,14304094 ! positive regulation of immune response GO:0050778 51 51 1,000 0,08122787 0,14380689 ! cholesterol metabolic process GO:0008203 52 52 1,000 0,08398617 0,14854751 ! regulation of body fluid levels GO:0050878 55 52 1,000 0,08398617 0,14840509 ! response to light stimulus GO:0009416 53 52 1,000 0,08398617 0,14826294 ! tRNA metabolic process GO:0006399 53 53 1,000 0,08677301 0,15303603 ! regulation of protein transport GO:0051223 53 53 1,000 0,08677301 0,15288973 GO:0070201|regulation of establishment of protein localization, ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,08928028 0,15715718 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,08928028 0,15700722 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,08928028 0,15685754 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,08928028 0,15670816 ! neuron maturation GO:0042551 10 10 0,000 0,08928028 0,15655905 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,08928028 0,15641023 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,08928028 0,15626169 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,08928028 0,15611344 ! hormone secretion GO:0046879 10 10 0,000 0,08928028 0,15596546 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,08928028 0,15581777 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,08928028 0,15567035 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,08928028 0,15552322 ! inositol metabolic process GO:0006020 10 10 0,000 0,08928028 0,15537636 ! cAMP metabolic process GO:0046058 10 10 0,000 0,08928028 0,15522978 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,08928028 0,15508347 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,08928028 0,15493744 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,08928028 0,15479169 ! glial cell development GO:0021782 10 10 0,000 0,08928028 0,15464621 ! phototransduction GO:0007602 11 10 0,000 0,08928028 0,154501 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,08928028 0,15435606 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,08928028 0,1542114 ! fat cell differentiation GO:0045444 10 10 0,000 0,08928028 0,15406701 ! myoblast differentiation GO:0045445 10 10 0,000 0,08928028 0,15392289 ! centrosome cycle GO:0007098 10 10 0,000 0,08928028 0,15377903 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,08928028 0,15363545 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,08928028 0,15349213 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,08928028 0,15334908 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,08928028 0,1532063 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,08928028 0,15306378 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,08928028 0,15292153 ! protein polyubiquitination GO:0000209 10 10 0,000 0,08928028 0,15277954 ! glutamate metabolic process GO:0006536 11 10 0,000 0,08928028 0,15263781 ! plasma membrane organization GO:0007009 10 10 0,000 0,08928028 0,15249635 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,08928028 0,15235515 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,08928028 0,15221421 ! lysosomal transport GO:0007041 10 10 0,000 0,08928028 0,15207353 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,08928028 0,15193312 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,08928028 0,15179296 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,08928028 0,15165305 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,08928028 0,15151341 ! exocrine system development GO:0035272 10 10 0,000 0,08928028 0,15137402 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,08928028 0,15123489 ! embryo implantation GO:0007566 11 10 0,000 0,08928028 0,15109602 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,08928028 0,1509574 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,08928028 0,15081903 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,08928028 0,15068092 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,08928028 0,15054306 ! protein export from nucleus GO:0006611 10 10 0,000 0,08928028 0,15040545 ! negative regulation of immune response GO:0050777 10 10 0,000 0,08928028 0,1502681 ! cytolysis GO:0019835 10 10 0,000 0,08928028 0,15013099 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,08928028 0,14999413 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,08928028 0,14985753 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,08928028 0,14972117 ! histone deacetylation GO:0016575 10 10 0,000 0,08928028 0,14958506 ! mRNA splice site selection GO:0006376 11 10 0,000 0,08928028 0,1494492 ! gland morphogenesis GO:0022612 10 10 0,000 0,08928028 0,14931358 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,08928028 0,14917821 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,08928028 0,14904308 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,08928028 0,1489082 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,08928028 0,14877357 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,08928028 0,14863917 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,08928028 0,14850502 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,08928028 0,14837111 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,08928028 0,14823745 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,08928028 0,14810402 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,08928028 0,14797083 ! nerve development GO:0021675 10 10 0,000 0,08928028 0,14783788 ! gut development GO:0048565 10 10 0,000 0,08928028 0,14770517 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,08928028 0,1475727 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,08928028 0,14744047 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,08928028 0,14730847 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,08928028 0,14717671 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,08958765 0,14755141 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,09242934 0,15209578 ! in utero embryonic development GO:0001701 55 55 1,000 0,09242934 0,15196011 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,09242934 0,15182467 ! extracellular structure organization GO:0043062 56 56 1,000 0,09529737 0,15639631 ! protein secretion GO:0009306 11 11 0,000 0,09776443 0,16030235 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,09776443 0,16015986 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,09776443 0,16001762 ! negative regulation of defense response GO:0031348 11 11 0,000 0,09776443 0,15987563 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,09776443 0,1597339 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,09776443 0,15959242 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,09776443 0,15945119 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,09776443 0,1593102 ! skin development GO:0043588 11 11 0,000 0,09776443 0,15916947 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,09776443 0,15902898 ! microtubule-based transport GO:0010970 11 11 0,000 0,09776443 0,15888875 ! endothelial cell migration GO:0043542 11 11 0,000 0,09776443 0,15874876 ! peroxisomal transport GO:0043574 11 11 0,000 0,09776443 0,15860901 ! protein amino acid methylation GO:0006479 11 11 0,000 0,09776443 0,15846952 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,09776443 0,15833026 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,09776443 0,15819126 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,09776443 0,15805249 ! T cell proliferation GO:0042098 11 11 0,000 0,09776443 0,15791397 ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,09776443 0,15777569 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,09776443 0,15763766 ! spinal cord development GO:0021510 11 11 0,000 0,09776443 0,15749986 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,09776443 0,15736231 ! smooth muscle contraction GO:0006939 11 11 0,000 0,09776443 0,15722499 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 0,000 0,09776443 0,15708792 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,09776443 0,15695108 ! mitotic spindle organization GO:0007052 11 11 0,000 0,09776443 0,15681448 ! fucose metabolic process GO:0006004 11 11 0,000 0,09776443 0,15667812 ! membrane budding GO:0006900 11 11 0,000 0,09776443 0,156542 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,09776443 0,15640611 ! monoamine transport GO:0015844 11 11 0,000 0,09776443 0,15627046 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,09776443 0,15613504 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,09776443 0,15599986 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,09776443 0,15586491 ! body fluid secretion GO:0007589 11 11 0,000 0,09776443 0,1557302 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,09776443 0,15559572 ! intermediate filament-based process GO:0045103 11 11 0,000 0,09776443 0,15546147 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,09776443 0,15532745 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,09776443 0,15519366 ! membrane depolarization GO:0051899 11 11 0,000 0,09776443 0,1550601 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,09776443 0,15492678 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,09776443 0,15479368 ! oogenesis GO:0048477 11 11 0,000 0,09776443 0,15466081 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,09776443 0,15452816 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,09776443 0,15439575 ! vitamin transport GO:0051180 11 11 0,000 0,09776443 0,15426356 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,09776443 0,1541316 ! hindbrain development GO:0030902 11 11 0,000 0,09776443 0,15399986 ! steroid catabolic process GO:0006706 11 11 0,000 0,09776443 0,15386835 ! endocrine process GO:0050886 11 11 0,000 0,09776443 0,15373706 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,09776443 0,153606 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,09776443 0,15347516 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,09776443 0,15334454 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,09776443 0,15321415 ! regulation of protein localization GO:0032880 58 57 1,000 0,09819101 0,15375194 ! sterol metabolic process GO:0016125 59 59 1,000 0,10405233 0,16279155 ! cellular aromatic compound metabolic process GO:0006725 60 59 1,000 0,10405233 0,16265347 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,10617076 0,16582433 ! translational initiation GO:0006413 12 12 0,000 0,10617076 0,16568392 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,10617076 0,16554374 ! initiation of viral infection GO:0019059 12 12 0,000 0,10617076 0,16540381 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,10617076 0,16526411 ! iron ion transport GO:0006826 13 12 0,000 0,10617076 0,16512465 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,10617076 0,16498542 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,10617076 0,16484642 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,10617076 0,16470766 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,10617076 0,16456914 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,10617076 0,16443084 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,10617076 0,16429278 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,10617076 0,16415495 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,10617076 0,16401736 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,10617076 0,16387999 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,10617076 0,16374285 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,10617076 0,16360594 ! actomyosin structure organization GO:0031032 12 12 0,000 0,10617076 0,16346926 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,10617076 0,16333281 GO:0051297|centrosome organization, ! retinoid metabolic process GO:0001523 12 12 0,000 0,10617076 0,16319658 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,10617076 0,16306059 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,10617076 0,16292482 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,10617076 0,16278927 GO:0006505|GPI anchor metabolic process, ! acute-phase response GO:0006953 12 12 0,000 0,10617076 0,16265395 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,10617076 0,16251886 ! vacuolar transport GO:0007034 12 12 0,000 0,10617076 0,16238399 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,10617076 0,16224934 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,10617076 0,16211492 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,10617076 0,16198072 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,10617076 0,16184674 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,10617076 0,16171298 ! male gonad development GO:0008584 12 12 0,000 0,10617076 0,16157944 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,10617076 0,16144613 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,10617076 0,16131303 ! renal system process GO:0003014 12 12 0,000 0,10617076 0,16118015 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,10617076 0,16104749 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,10617076 0,16091505 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,10617076 0,16078283 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,10617076 0,16065083 ! pallium development GO:0021543 13 12 0,000 0,10617076 0,16051904 ! cell fate determination GO:0001709 12 12 0,000 0,10617076 0,16038746 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,10617076 0,16025611 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,10617076 0,16012496 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,10617076 0,15999404 ! detection of light stimulus GO:0009583 13 12 0,000 0,10617076 0,15986332 ! synaptogenesis GO:0007416 12 12 0,000 0,10617076 0,15973282 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,10617076 0,15960253 ! hormone transport GO:0009914 12 12 0,000 0,10617076 0,15947246 ! heme biosynthetic process GO:0006783 12 12 0,000 0,10617076 0,15934259 ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,10617076 0,15921294 ! neural tube closure GO:0001843 13 12 0,000 0,10617076 0,1590835 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! negative regulation of translation GO:0017148 12 12 0,000 0,10617076 0,15895427 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,10617076 0,15882525 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,10617076 0,15869644 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,10701862 0,15983413 ! protein polymerization GO:0051258 65 60 1,000 0,10701862 0,15970471 ! cellular respiration GO:0045333 62 61 1,000 0,11000776 0,16403261 ! lipid transport GO:0006869 62 62 1,000 0,1130191 0,16838658 ! morphogenesis of an epithelium GO:0002009 63 62 1,000 0,1130191 0,16825056 GO:0060429|epithelium development, ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,1130191 0,16811477 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 1,000 0,1130191 0,16797919 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,11449998 0,17004307 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,11449998 0,16990616 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,11449998 0,16976947 ! phenol metabolic process GO:0018958 13 13 0,000 0,11449998 0,169633 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,11449998 0,16949675 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,11449998 0,16936072 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,11449998 0,1692249 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,11449998 0,16908931 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,11449998 0,16895393 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,11449998 0,16881876 ! regeneration GO:0031099 13 13 0,000 0,11449998 0,16868382 ! keratinization GO:0031424 13 13 0,000 0,11449998 0,16854908 ! post-embryonic development GO:0009791 14 13 0,000 0,11449998 0,16841457 ! patterning of blood vessels GO:0001569 13 13 0,000 0,11449998 0,16828027 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,11449998 0,16814618 ! regulation of innate immune response GO:0045088 13 13 0,000 0,11449998 0,1680123 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,11449998 0,16787864 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 0,000 0,11449998 0,16774519 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,11449998 0,16761196 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,11449998 0,16747893 ! autophagy GO:0006914 13 13 0,000 0,11449998 0,16734612 ! ureteric bud development GO:0001657 13 13 0,000 0,11449998 0,16721351 ! cell aging GO:0007569 13 13 0,000 0,11449998 0,16708112 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,11449998 0,16694894 ! response to endoplasmic reticulum stress GO:0034976 13 13 0,000 0,11449998 0,16681696 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,11449998 0,16668519 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,11449998 0,16655363 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,11449998 0,16642228 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,11449998 0,16629114 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,11449998 0,1661602 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,11449998 0,16602947 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,11449998 0,16589894 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,11449998 0,16576862 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,11449998 0,1656385 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,11449998 0,16550859 ! vasodilation GO:0042311 14 13 0,000 0,11449998 0,16537888 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,11449998 0,16524938 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,11449998 0,16512007 GO:0006664|glycolipid metabolic process, ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,11449998 0,16499097 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,11449998 0,16486207 ! immunoglobulin production GO:0002377 13 13 0,000 0,11449998 0,16473338 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,11449998 0,16460488 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,11449998 0,16447658 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,11449998 0,16434848 ! cell-cell junction organization GO:0045216 13 13 0,000 0,11449998 0,16422059 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,11449998 0,16409289 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,11449998 0,16396539 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,11449998 0,16383809 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,11449998 0,16371098 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,11449998 0,16358407 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,11449998 0,16345736 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,11449998 0,16333085 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,11449998 0,16320453 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,11449998 0,1630784 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,11449998 0,16295247 ! blastocyst development GO:0001824 13 13 0,000 0,11449998 0,16282674 ! telomere organization GO:0032200 13 13 0,000 0,11449998 0,1627012 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,11449998 0,16257585 ! regulation of amine transport GO:0051952 13 13 0,000 0,11449998 0,1624507 ! tissue homeostasis GO:0001894 13 13 0,000 0,11449998 0,16232573 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,11449998 0,16220096 ! protein tetramerization GO:0051262 13 13 0,000 0,11449998 0,16207639 ! regulation of secretion GO:0051046 65 63 1,000 0,11605196 0,16414717 ! glycerolipid metabolic process GO:0046486 65 64 1,000 0,11910572 0,1683373 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 0,11910572 0,1682083 ! neuron fate commitment GO:0048663 14 14 0,000 0,12275278 0,17322616 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,12275278 0,17309363 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,12275278 0,17296129 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,12275278 0,17282916 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,12275278 0,17269723 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,12275278 0,1725655 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,12275278 0,17243397 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,12275278 0,17230264 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,12275278 0,17217152 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,12275278 0,17204059 ! vesicle docking GO:0048278 14 14 0,000 0,12275278 0,17190986 ! superoxide metabolic process GO:0006801 15 14 0,000 0,12275278 0,17177933 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,12275278 0,17164899 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,12275278 0,17151886 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,12275278 0,17138892 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,12275278 0,17125918 ! hair cycle GO:0042633 14 14 0,000 0,12275278 0,17112963 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! response to retinoic acid GO:0032526 14 14 0,000 0,12275278 0,17100028 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,12275278 0,17087113 ! lysosome organization GO:0007040 14 14 0,000 0,12275278 0,17074217 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,12275278 0,1706134 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,12275278 0,17048483 ! peptide transport GO:0015833 14 14 0,000 0,12275278 0,17035645 ! primary neural tube formation GO:0014020 15 14 0,000 0,12275278 0,17022827 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,12275278 0,17010028 ! base-excision repair GO:0006284 14 14 0,000 0,12275278 0,16997248 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,12275278 0,16984487 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,12275278 0,16971746 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,12275278 0,16959023 ! formation of primary germ layer GO:0001704 14 14 0,000 0,12275278 0,1694632 GO:0001707|mesoderm formation, ! collagen fibril organization GO:0030199 14 14 0,000 0,12275278 0,16933636 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,12275278 0,1692097 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,12275278 0,16908324 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,12275278 0,16895696 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,12275278 0,16883087 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,12275278 0,16870497 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,12275278 0,16857926 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,12275278 0,16845374 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,12275278 0,1683284 ! regulation of MAP kinase activity GO:0043405 67 66 1,000 0,12527336 0,1716571 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,13092986 0,17927469 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,13092986 0,17914159 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,13092986 0,1790087 ! positive regulation of ossification GO:0045778 15 15 0,000 0,13092986 0,178876 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,13092986 0,1787435 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,13092986 0,1786112 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,13092986 0,17847909 ! response to vitamin GO:0033273 15 15 0,000 0,13092986 0,17834717 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,13092986 0,17821546 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,13092986 0,17808393 ! ovarian follicle development GO:0001541 15 15 0,000 0,13092986 0,1779526 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,13092986 0,17782146 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,13092986 0,17769052 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,13092986 0,17755977 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,13092986 0,17742921 ! ER-nuclear signaling pathway GO:0006984 15 15 0,000 0,13092986 0,17729884 ! heme metabolic process GO:0042168 15 15 0,000 0,13092986 0,17716867 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,13092986 0,17703868 ! chromosome condensation GO:0030261 15 15 0,000 0,13092986 0,17690889 ! response to ionizing radiation GO:0010212 16 15 0,000 0,13092986 0,17677929 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,13092986 0,17664987 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,13092986 0,17652065 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,13092986 0,17639161 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,13092986 0,17626277 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,13092986 0,17613411 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,13092986 0,17600564 ! phospholipid transport GO:0015914 15 15 0,000 0,13092986 0,17587735 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,13092986 0,17574926 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,13092986 0,17562134 ! glutathione metabolic process GO:0006749 16 15 0,000 0,13092986 0,17549362 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,13092986 0,17536608 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,13092986 0,17523873 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,13092986 0,17511156 ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,13092986 0,17498457 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,13092986 0,17485777 ! protein homooligomerization GO:0051260 15 15 0,000 0,13092986 0,17473116 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,13092986 0,17460472 ! chromatin assembly or disassembly GO:0006333 68 68 1,000 0,13151706 0,17526099 ! growth GO:0040007 70 70 1,000 0,13783202 0,18354364 ! carboxylic acid biosynthetic process GO:0046394 70 70 1,000 0,13783202 0,18341112 GO:0016053|organic acid biosynthetic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,1390319 0,1848743 ! alkaloid metabolic process GO:0009820 16 16 0,000 0,1390319 0,18474101 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,1390319 0,18460791 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,1390319 0,18447501 ! learning GO:0007612 16 16 0,000 0,1390319 0,18434229 ! circadian rhythm GO:0007623 16 16 0,000 0,1390319 0,18420976 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,1390319 0,18407743 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,1390319 0,18394529 ! vacuole organization GO:0007033 16 16 0,000 0,1390319 0,18381333 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,1390319 0,18368156 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,1390319 0,18354999 ! positive regulation of cell development GO:0010720 16 16 0,000 0,1390319 0,1834186 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,1390319 0,1832874 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,1390319 0,18315639 ! cell fate specification GO:0001708 16 16 0,000 0,1390319 0,18302556 ! pentose metabolic process GO:0019321 16 16 0,000 0,1390319 0,18289492 ! fatty acid transport GO:0015908 16 16 0,000 0,1390319 0,18276447 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,1390319 0,1826342 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,1390319 0,18250412 ! cofactor catabolic process GO:0051187 16 16 0,000 0,1390319 0,18237422 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,1390319 0,18224451 ! polyol metabolic process GO:0019751 16 16 0,000 0,1390319 0,18211498 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,1390319 0,18198564 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,1390319 0,18185648 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,1390319 0,18172751 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,1390319 0,18159871 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,1390319 0,1814701 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,1390319 0,18134167 ! regulation of coagulation GO:0050818 17 16 0,000 0,1390319 0,18121342 ! oxidative phosphorylation GO:0006119 71 71 1,000 0,14101474 0,18366797 ! calcium ion homeostasis GO:0055074 71 71 1,000 0,14101474 0,18353826 GO:0006874|cellular calcium ion homeostasis, ! secretion by cell GO:0032940 75 72 1,000 0,14421355 0,18756921 ! regulation of cytokine production GO:0001817 72 72 1,000 0,14421355 0,18743693 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,14705957 0,19100126 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,14705957 0,19086675 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,14705957 0,19073243 ! positive regulation of cell adhesion GO:0045785 17 17 0,000 0,14705957 0,1905983 ! myelination GO:0042552 17 17 0,000 0,14705957 0,19046436 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,14705957 0,19033061 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,14705957 0,19019704 ! leukocyte adhesion GO:0007159 17 17 0,000 0,14705957 0,19006367 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,14705957 0,18993047 ! sensory perception of smell GO:0007608 17 17 0,000 0,14705957 0,18979747 ! glucose transport GO:0015758 17 17 0,000 0,14705957 0,18966465 ! cell junction assembly GO:0034329 18 17 0,000 0,14705957 0,18953202 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,14705957 0,18939957 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,14705957 0,18926731 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,14705957 0,18913523 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,14705957 0,18900334 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,14705957 0,18887163 ! response to toxin GO:0009636 18 17 0,000 0,14705957 0,1887401 ! negative regulation of cell development GO:0010721 18 17 0,000 0,14705957 0,18860876 GO:0050768|negative regulation of neurogenesis, ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,14705957 0,1884776 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,14705957 0,18834662 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,14705957 0,18821582 ! adult locomotory behavior GO:0008344 17 17 0,000 0,14705957 0,18808521 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,14705957 0,18795478 ! liver development GO:0001889 17 17 0,000 0,14705957 0,18782452 ! gene silencing GO:0016458 17 17 0,000 0,14705957 0,18769445 ! electron transport chain GO:0022900 75 74 1,000 0,15065713 0,19215301 ! coenzyme metabolic process GO:0006732 75 74 1,000 0,15065713 0,19202012 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,15501355 0,19743606 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,15501355 0,19729971 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,15501355 0,19716355 ! membrane docking GO:0022406 18 18 0,000 0,15501355 0,19702757 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,15501355 0,19689178 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,15501355 0,19675618 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,15501355 0,19662077 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,15501355 0,19648554 ! hexose transport GO:0008645 18 18 0,000 0,15501355 0,1963505 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,15501355 0,19621564 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,15501355 0,19608097 ! striated muscle contraction GO:0006941 18 18 0,000 0,15501355 0,19594649 ! ceramide metabolic process GO:0006672 18 18 0,000 0,15501355 0,19581219 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,15501355 0,19567807 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,15501355 0,19554413 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,15501355 0,19541038 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,15501355 0,19527681 ! B cell differentiation GO:0030183 18 18 0,000 0,15501355 0,19514343 ! ensheathment of neurons GO:0007272 18 18 0,000 0,15501355 0,19501022 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,15501355 0,1948772 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,15501355 0,19474436 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,15501355 0,1946117 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,15715839 0,19717013 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,16042932 0,20113689 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,16042932 0,20100016 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,16289451 0,20395012 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,16289451 0,20381167 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,16289451 0,20367339 ! regulation of pH GO:0006885 19 19 0,000 0,16289451 0,20353531 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,16289451 0,20339741 ! feeding behavior GO:0007631 19 19 0,000 0,16289451 0,2032597 ! peroxisome organization GO:0007031 19 19 0,000 0,16289451 0,20312218 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,16289451 0,20298484 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,16289451 0,20284769 ! metanephros development GO:0001656 19 19 0,000 0,16289451 0,20271072 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,16289451 0,20257394 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,16289451 0,20243735 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,16289451 0,20230093 ! peripheral nervous system development GO:0007422 19 19 0,000 0,16289451 0,2021647 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,16289451 0,20202866 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,16289451 0,20189279 ! eye morphogenesis GO:0048592 19 19 0,000 0,16289451 0,20175711 ! response to heat GO:0009408 19 19 0,000 0,16289451 0,20162161 ! microtubule-based movement GO:0007018 82 78 1,000 0,16371308 0,2024988 ! metal ion homeostasis GO:0055065 78 78 1,000 0,16371308 0,20236298 ! regulation of immune response GO:0050776 78 78 1,000 0,16371308 0,20222735 ! regulation of protein modification process GO:0031399 79 78 1,000 0,16371308 0,2020919 ! regulation of muscle development GO:0048634 21 20 0,000 0,1707031 0,21057953 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,1707031 0,21043868 ! neural tube development GO:0021915 21 20 0,000 0,1707031 0,21029801 ! nucleus organization GO:0006997 20 20 0,000 0,1707031 0,21015753 ! phagocytosis GO:0006909 21 20 0,000 0,1707031 0,21001724 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,1707031 0,20987713 ! protein targeting to membrane GO:0006612 22 20 0,000 0,1707031 0,20973721 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,1707031 0,20959748 ! chromatin remodeling GO:0006338 20 20 0,000 0,1707031 0,20945794 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,1707031 0,20931858 ! lipid oxidation GO:0034440 20 20 0,000 0,1707031 0,2091794 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,1707031 0,20904041 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,1707031 0,20890161 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,1707031 0,20876299 ! single fertilization GO:0007338 21 20 0,000 0,1707031 0,20862455 ! regulation of B cell activation GO:0050864 20 20 0,000 0,1707031 0,2084863 ! lymphocyte activation GO:0046649 82 81 1,000 0,17363632 0,21192831 ! lipid catabolic process GO:0016042 82 81 1,000 0,17363632 0,21178805 ! mRNA catabolic process GO:0006402 21 21 0,000 0,17843998 0,21750323 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,17843998 0,21735948 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,17843998 0,21721591 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,17843998 0,21707253 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,17843998 0,21692935 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,17843998 0,21678635 ! ear morphogenesis GO:0042471 21 21 0,000 0,17843998 0,21664354 ! organic anion transport GO:0015711 21 21 0,000 0,17843998 0,21650092 ! cholesterol transport GO:0030301 21 21 0,000 0,17843998 0,21635848 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,17843998 0,21621623 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,17843998 0,21607417 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,17843998 0,2159323 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,17843998 0,21579061 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,17843998 0,21564911 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,17843998 0,21550779 ! regulation of proteolysis GO:0030162 21 21 0,000 0,17843998 0,21536666 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,17843998 0,21522571 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,17843998 0,21508495 ! ncRNA processing GO:0034470 83 83 1,000 0,18030686 0,21719317 ! RNA export from nucleus GO:0006405 22 22 0,000 0,1861058 0,224032 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,1861058 0,22388576 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,1861058 0,22373972 ! regulation of ion transport GO:0043269 22 22 0,000 0,1861058 0,22359387 ! odontogenesis GO:0042476 22 22 0,000 0,1861058 0,2234482 ! cell junction organization GO:0034330 23 22 0,000 0,1861058 0,22330273 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,1861058 0,22315744 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,1861058 0,22301235 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,1861058 0,22286744 ! ovulation cycle process GO:0022602 22 22 0,000 0,1861058 0,22272272 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,1861058 0,22257819 ! cell chemotaxis GO:0060326 23 22 0,000 0,1861058 0,22243385 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,1861058 0,22228969 ! male sex differentiation GO:0046661 22 22 0,000 0,1861058 0,22214572 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,1861058 0,22200194 ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,1861058 0,22185834 ! detection of external stimulus GO:0009581 23 22 0,000 0,1861058 0,22171493 ! neuron migration GO:0001764 22 22 0,000 0,1861058 0,2215717 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,1861058 0,22142866 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,1861058 0,2212858 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,1861058 0,22114313 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,1861058 0,22100064 ! aerobic respiration GO:0009060 22 22 0,000 0,1861058 0,22085833 ! cytokine production GO:0001816 22 22 0,000 0,1861058 0,22071621 ! organophosphate metabolic process GO:0019637 87 86 1,000 0,19038574 0,2256469 GO:0006644|phospholipid metabolic process, ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,1937012 0,22942886 ! viral infectious cycle GO:0019058 23 23 0,000 0,1937012 0,22928151 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,1937012 0,22913434 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,1937012 0,22898737 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,1937012 0,22884058 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,1937012 0,22869398 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,1937012 0,22854757 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,1937012 0,22840135 ! endocrine system development GO:0035270 23 23 0,000 0,1937012 0,22825531 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,1937012 0,22810946 ! positive regulation of growth GO:0045927 23 23 0,000 0,1937012 0,2279638 ! female gonad development GO:0008585 23 23 0,000 0,1937012 0,22781832 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,1937012 0,22767303 ! lipid homeostasis GO:0055088 23 23 0,000 0,1937012 0,22752792 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,1937012 0,227383 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,1937012 0,22723826 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,1937012 0,22709371 ! mitochondrial transport GO:0006839 24 24 0,000 0,20122681 0,23576669 ! regulation of action potential GO:0001508 24 24 0,000 0,20122681 0,23561691 ! gliogenesis GO:0042063 24 24 0,000 0,20122681 0,23546731 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,20122681 0,2353179 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,20122681 0,23516868 ! ovulation cycle GO:0042698 24 24 0,000 0,20122681 0,23501965 ! fertilization GO:0009566 25 24 0,000 0,20122681 0,23487081 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,20122681 0,23472216 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,20122681 0,23457369 ! glucan metabolic process GO:0044042 25 24 0,000 0,20122681 0,23442542 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,20868327 0,24295847 ! negative regulation of secretion GO:0051048 26 25 0,000 0,20868327 0,24280509 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,20868327 0,2426519 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,20868327 0,24249891 ! cellular component disassembly GO:0022411 26 25 0,000 0,20868327 0,2423461 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,20868327 0,24219349 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,20868327 0,24204107 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,20868327 0,24188885 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,20868327 0,24173681 ! excretion GO:0007588 25 25 0,000 0,20868327 0,24158497 ! gastrulation GO:0007369 25 25 0,000 0,20868327 0,24143331 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,20868327 0,24128185 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,20868327 0,24113057 ! fatty acid metabolic process GO:0006631 93 92 1,000 0,2107622 0,24338016 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,2107622 0,24322776 ! tissue morphogenesis GO:0048729 94 93 1,000 0,21418165 0,24701926 ! glycolysis GO:0006096 26 26 0,000 0,2160712 0,24904267 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,2160712 0,24888701 ! cellular defense response GO:0006968 26 26 0,000 0,2160712 0,24873156 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,2160712 0,24857629 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,2160712 0,24842122 ! double-strand break repair GO:0006302 27 26 0,000 0,2160712 0,24826635 ! regulation of protein secretion GO:0050708 26 26 0,000 0,2160712 0,24811167 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,2160712 0,24795717 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,2160712 0,24780288 ! regulation of response to stress GO:0080134 97 94 1,000 0,21760668 0,24940866 ! epidermis development GO:0008544 94 94 1,000 0,21760668 0,24925365 ! cofactor metabolic process GO:0051186 95 94 1,000 0,21760668 0,24909883 ! chloride transport GO:0006821 27 27 0,000 0,22339122 0,25556178 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,22339122 0,25540324 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,22339122 0,2552449 ! peptide metabolic process GO:0006518 29 27 0,000 0,22339122 0,25508676 ! activation of caspase activity GO:0006919 27 27 0,000 0,22339122 0,25492881 ! inner ear development GO:0048839 27 27 0,000 0,22339122 0,25477106 ! defense response to bacterium GO:0042742 27 27 0,000 0,22339122 0,2546135 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,22339122 0,25445614 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,22339122 0,25429897 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,23064395 0,26239309 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,23064395 0,26223122 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,23064395 0,26206955 ! carbohydrate transport GO:0008643 28 28 0,000 0,23064395 0,26190808 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,23064395 0,2617468 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,23064395 0,26158573 ! protein amino acid autophosphorylation GO:0046777 28 28 0,000 0,23064395 0,26142485 ! developmental growth GO:0048589 28 28 0,000 0,23064395 0,26126417 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,23064395 0,26110369 ! endocytosis GO:0006897 99 98 1,000 0,23135501 0,26174787 GO:0010324|membrane invagination, ! anti-apoptosis GO:0006916 100 99 1,000 0,23480225 0,265485 ! ectoderm development GO:0007398 99 99 1,000 0,23480225 0,26532223 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,23783 0,26857886 ! viral reproductive process GO:0022415 29 29 0,000 0,23783 0,26841439 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,23783 0,26825012 ! leukocyte migration GO:0050900 30 29 0,000 0,23783 0,26808605 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,23783 0,26792218 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,23783 0,26775852 ! adult behavior GO:0030534 30 29 0,000 0,23783 0,26759505 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,23783 0,26743178 ! response to hormone stimulus GO:0009725 102 100 1,000 0,23825283 0,26774389 ! transition metal ion transport GO:0000041 31 30 0,000 0,24494997 0,27510225 ! RNA catabolic process GO:0006401 30 30 0,000 0,24494997 0,27493471 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,24494997 0,27476737 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,24494997 0,27460024 GO:0043280|positive regulation of caspase activity, ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,24494997 0,27443331 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,24494997 0,27426658 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,24494997 0,27410005 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,24494997 0,27393373 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,24494997 0,27376761 ! regulation of ossification GO:0030278 30 30 0,000 0,24494997 0,27360169 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,24494997 0,27343597 GO:0019724|B cell mediated immunity, ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,24494997 0,27327045 ! vesicle organization GO:0016050 30 30 0,000 0,24494997 0,27310513 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,24494997 0,27294002 ! regulation of translational initiation GO:0006446 31 31 0,000 0,25200445 0,28063093 ! membrane fusion GO:0006944 31 31 0,000 0,25200445 0,28046147 ! B cell activation GO:0042113 31 31 0,000 0,25200445 0,28029221 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,25200445 0,28012316 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,25200445 0,27995431 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,25200445 0,27978566 ! ion transmembrane transport GO:0034220 31 31 0,000 0,25200445 0,27961722 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,25200445 0,27944898 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,25200445 0,27928094 ! regulation of heart contraction GO:0008016 31 31 0,000 0,25200445 0,2791131 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,25200445 0,27894546 ! camera-type eye development GO:0043010 31 31 0,000 0,25200445 0,27877803 ! extracellular matrix organization GO:0030198 31 31 0,000 0,25200445 0,2786108 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,25200445 0,27844376 ! cell redox homeostasis GO:0045454 32 32 0,000 0,25899404 0,28599522 ! glucose catabolic process GO:0006007 32 32 0,000 0,25899404 0,28582396 ! lipid modification GO:0030258 32 32 0,000 0,25899404 0,28565291 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,25899404 0,28548207 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,25899404 0,28531143 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,25899404 0,28514099 ! nuclear export GO:0051168 32 32 0,000 0,25899404 0,28497076 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,25899404 0,28480073 ! kidney development GO:0001822 32 32 0,000 0,25899404 0,2846309 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,25899404 0,28446127 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,26591933 0,29189358 ! amino acid transport GO:0006865 33 33 0,000 0,26591933 0,29171984 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,26591933 0,2915463 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,26591933 0,29137296 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,26591933 0,29119984 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,26591933 0,29102691 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,26591933 0,2908542 ! ear development GO:0043583 34 34 0,000 0,2727809 0,2981822 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,2727809 0,29800545 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,2727809 0,29782891 ! secondary metabolic process GO:0019748 34 34 0,000 0,2727809 0,29765257 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,2727809 0,29747645 ! viral reproduction GO:0016032 34 34 0,000 0,2727809 0,29730053 ! detection of stimulus GO:0051606 36 34 0,000 0,2727809 0,29712482 ! acute inflammatory response GO:0002526 35 35 0,000 0,27957932 0,30435009 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,27957932 0,30417042 ! mesoderm development GO:0007498 35 35 0,000 0,27957932 0,30399097 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,27957932 0,30381173 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,27957932 0,3036327 ! inorganic anion transport GO:0015698 35 35 0,000 0,27957932 0,30345388 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,27957932 0,30327528 ! regulation of immune effector process GO:0002697 35 35 0,000 0,27957932 0,30309688 ! hydrogen transport GO:0006818 36 36 0,000 0,28631518 0,31021686 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,28631518 0,31003459 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,28631518 0,30985254 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,28631518 0,3096707 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,28631518 0,30948908 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,28631518 0,30930766 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,28631518 0,30912646 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,28631518 0,30894548 ! gonad development GO:0008406 36 36 0,000 0,28631518 0,3087647 ! regulation of lipase activity GO:0060191 36 36 0,000 0,28631518 0,30858414 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,29298903 0,31559251 ! eye development GO:0001654 37 37 0,000 0,29298903 0,31540817 ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,29298903 0,31522404 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,29298903 0,31504013 ! hexose catabolic process GO:0019320 38 38 0,000 0,29960144 0,32196236 ! RNA elongation GO:0006354 38 38 0,000 0,29960144 0,32177474 ! axon guidance GO:0007411 39 38 0,000 0,29960144 0,32158733 ! regulation of neurological system process GO:0031644 38 38 0,000 0,29960144 0,32140014 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,30615296 0,32823729 ! activation of MAPK activity GO:0000187 39 39 0,000 0,30615296 0,32804645 ! response to unfolded protein GO:0006986 39 39 0,000 0,30615296 0,32785584 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,30615296 0,32766545 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,30615296 0,32747528 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,30615296 0,32728532 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,30615296 0,32709559 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,30615296 0,32690608 ! DNA catabolic process GO:0006308 41 40 0,000 0,31264414 0,33364398 ! amine catabolic process GO:0009310 42 41 0,000 0,31907554 0,34031032 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,31907554 0,34011349 ! regulation of caspase activity GO:0043281 41 41 0,000 0,31907554 0,33991689 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,31907554 0,33972052 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,31907554 0,33952438 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,31907554 0,33932846 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,31907554 0,33913277 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,3254477 0,34570611 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,3254477 0,34550697 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,3254477 0,34530806 ! protein ubiquitination GO:0016567 43 42 0,000 0,3254477 0,34510938 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,3254477 0,34491093 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,3254477 0,34471271 ! forebrain development GO:0030900 43 42 0,000 0,3254477 0,34451471 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,3254477 0,34431694 ! mitochondrion organization GO:0007005 44 43 0,000 0,33176114 0,35079506 ! alcohol catabolic process GO:0046164 43 43 0,000 0,33176114 0,35059392 ! humoral immune response GO:0006959 44 44 0,000 0,33801642 0,35699957 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,33801642 0,35679511 ! mRNA transport GO:0051028 44 44 0,000 0,33801642 0,35659087 ! protein import into nucleus GO:0006606 44 44 0,000 0,33801642 0,35638687 ! vitamin metabolic process GO:0006766 44 44 0,000 0,33801642 0,35618311 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,33801642 0,35597957 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,34421404 0,36229953 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,34421404 0,36209274 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,34421404 0,36188618 ! nuclear import GO:0051170 45 45 0,000 0,34421404 0,36167986 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,35035454 0,36792217 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,35035454 0,36771265 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,35035454 0,36750336 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,35035454 0,36729432 ! regulation of membrane potential GO:0042391 46 46 0,000 0,35035454 0,36708551 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,35643843 0,37324774 ! regulation of blood pressure GO:0008217 48 47 0,000 0,35643843 0,37303579 ! amine transport GO:0015837 47 47 0,000 0,35643843 0,37282408 ! rhythmic process GO:0048511 47 47 0,000 0,35643843 0,3726126 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,36246622 0,37869912 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,36246622 0,37848456 ! protein localization in nucleus GO:0034504 48 48 0,000 0,36246622 0,37827024 ! ossification GO:0001503 50 49 0,000 0,36843844 0,38428525 GO:0060348|bone development, ! response to bacterium GO:0009617 50 49 0,000 0,36843844 0,3840679 ! regulation of ligase activity GO:0051340 50 49 0,000 0,36843844 0,38385079 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,36843844 0,38363392 GO:0002696|positive regulation of leukocyte activation, ! chromatin assembly GO:0031497 50 50 0,000 0,37435557 0,389575 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,37435557 0,38935515 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,37435557 0,38913554 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,37435557 0,38891619 ! transcription initiation GO:0006352 50 50 0,000 0,37435557 0,38869708 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,38021813 0,39456194 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,38021813 0,3943399 ! rRNA metabolic process GO:0016072 51 51 0,000 0,38021813 0,39411811 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,38021813 0,39389657 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,38021813 0,39367528 ! RNA localization GO:0006403 52 52 0,000 0,38602659 0,39946492 ! cell fate commitment GO:0045165 52 52 0,000 0,38602659 0,39924075 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,38602659 0,39901683 ! sodium ion transport GO:0006814 53 53 0,000 0,39178147 0,40473837 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,39178147 0,40451163 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,39178147 0,40428514 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,39178147 0,4040589 ! regulation of T cell activation GO:0050863 53 53 0,000 0,39178147 0,40383292 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,39748324 0,40948106 ! response to virus GO:0009615 54 54 0,000 0,39748324 0,4092523 ! sulfur metabolic process GO:0006790 55 54 0,000 0,39748324 0,40902379 ! nucleosome organization GO:0034728 55 55 0,000 0,40313239 0,41460546 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,40313239 0,41437423 ! regulation of nervous system development GO:0051960 57 56 0,000 0,40872939 0,41989312 ! ATP metabolic process GO:0046034 57 57 0,000 0,41427472 0,42535281 ! innate immune response GO:0045087 58 58 0,000 0,41976884 0,43075388 ! dephosphorylation GO:0016311 60 59 0,000 0,42521223 0,43609691 ! carboxylic acid transport GO:0046942 59 59 0,000 0,42521223 0,43585436 GO:0015849|organic acid transport, ! regulation of cell development GO:0060284 60 59 0,000 0,42521223 0,43561208 ! protein localization in organelle GO:0033365 59 59 0,000 0,42521223 0,43537008 ! immune effector process GO:0002252 59 59 0,000 0,42521223 0,43512834 ! potassium ion transport GO:0006813 60 60 0,000 0,43060534 0,44040269 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,43594864 0,44562026 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of protein amino acid phosphorylation GO:0001932 62 61 0,000 0,43594864 0,44537325 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,43594864 0,4451265 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,43594864 0,44488003 ! axonogenesis GO:0007409 66 62 0,000 0,44124256 0,45003323 ! protein import GO:0017038 62 62 0,000 0,44124256 0,44978432 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,44124256 0,44953568 ! glucose metabolic process GO:0006006 63 63 0,000 0,44648757 0,45462795 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,45168411 0,45966528 ! anion transport GO:0006820 65 65 0,000 0,45683262 0,46464818 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,46193353 0,46957721 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! DNA packaging GO:0006323 66 66 0,000 0,46193353 0,46931835 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,46193353 0,46905977 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 0,000 0,46698728 0,47393037 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 0,000 0,46698728 0,47366954 ! muscle contraction GO:0006936 67 67 0,000 0,46698728 0,47340899 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,46698728 0,47314874 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,46698728 0,47288876 ! regulation of translation GO:0006417 69 69 0,000 0,47695501 0,48271723 ! sensory perception of sound GO:0007605 71 69 0,000 0,47695501 0,48245229 GO:0050954|sensory perception of mechanical stimulus, ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,47695501 0,48218765 ! cell part morphogenesis GO:0032990 75 70 0,000 0,48186983 0,48688931 ! translational elongation GO:0006414 71 71 0,000 0,48673919 0,49153991 ! negative regulation of signal transduction GO:0009968 71 71 0,000 0,48673919 0,49127072 ! regulation of cell activation GO:0050865 71 71 0,000 0,48673919 0,49100182 ! muscle system process GO:0003012 72 72 0,000 0,4915635 0,49559711 ! positive regulation of hydrolase activity GO:0051345 72 72 0,000 0,4915635 0,49532615 ! sensory organ development GO:0007423 72 72 0,000 0,4915635 0,49505548 ! negative regulation of cell communication GO:0010648 76 76 0,000 0,51041833 0,51376351 ! nuclear transport GO:0051169 79 79 0,000 0,52410614 0,52725306 GO:0006913|nucleocytoplasmic transport, ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,52858448 0,53146819 ! neuron projection development GO:0031175 85 80 0,000 0,52858448 0,5311784 ! MAPKKK cascade GO:0000165 82 81 0,000 0,53302133 0,53534513 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,54608671 0,54816874 ! hexose metabolic process GO:0019318 87 86 0,000 0,55459636 0,55640778 ! chemotaxis GO:0006935 90 89 0,000 0,56706718 0,5686098 GO:0042330|taxis, ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,57114725 0,57238955 ! brain development GO:0007420 91 90 0,000 0,57114725 0,57207846 ! visual perception GO:0007601 93 92 0,000 0,57919415 0,57982336 GO:0050953|sensory perception of light stimulus, ! regulation of system process GO:0044057 98 98 0,000 0,60245357 0,60278063 ! response to other organism GO:0051707 101 100 0,000 0,6099218 0,6099218