pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6521-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 7,000 1,792E-09 4,313E-06 ! interphase of mitotic cell cycle GO:0051329 209 95 8,000 6,015E-09 7,236E-06 ! interphase GO:0051325 213 98 8,000 7,933E-09 6,362E-06 ! cell cycle checkpoint GO:0000075 137 69 7,000 8,534E-09 5,133E-06 ! regulation of lipid kinase activity GO:0043550 13 7 3,000 4,259E-08 2,049E-05 ! macrophage differentiation GO:0030225 11 7 3,000 4,259E-08 1,708E-05 ! UTP metabolic process GO:0046051 8 8 3,000 8,478E-08 2,914E-05 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! CTP metabolic process GO:0046036 9 9 3,000 1,519E-07 4,568E-05 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 9 9 3,000 1,519E-07 4,061E-05 ! sex determination GO:0007530 47 23 4,000 2,224E-07 5,351E-05 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 3,000 2,52E-07 5,512E-05 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 5,000 3,22E-07 6,456E-05 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 4,000 3,478E-07 6,437E-05 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 3,000 5,884E-07 1,011E-04 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 3,000 1,179E-06 1,891E-04 ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 3,000 1,6E-06 2,406E-04 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 3,000 1,6E-06 2,264E-04 ! Notch receptor processing GO:0007220 8 5 2,000 2,081E-06 2,782E-04 ! L-serine biosynthetic process GO:0006564 6 5 2,000 2,081E-06 2,635E-04 ! regulation of keratinocyte differentiation GO:0045616 6 5 2,000 2,081E-06 2,504E-04 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 3,000 2,764E-06 3,166E-04 ! nuclear migration GO:0007097 12 6 2,000 4,144E-06 4,532E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 4,144E-06 4,335E-04 GO:0031272|regulation of pseudopodium assembly, ! triglyceride catabolic process GO:0019433 10 6 2,000 4,144E-06 4,154E-04 ! C21-steroid hormone metabolic process GO:0008207 33 20 3,000 5,548E-06 5,339E-04 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 3,000 5,548E-06 5,134E-04 ! prostate gland development GO:0030850 13 7 2,000 7,22E-06 6,434E-04 ! amyloid precursor protein catabolic process GO:0042987 11 7 2,000 7,22E-06 6,204E-04 ! glycerol ether catabolic process GO:0044269 12 7 2,000 7,22E-06 5,99E-04 GO:0046464|acylglycerol catabolic process, ! regulation of epidermal cell differentiation GO:0045604 8 7 2,000 7,22E-06 5,791E-04 ! myeloid leukocyte differentiation GO:0002573 40 23 3,000 9,998E-06 7,76E-04 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 3,000 9,998E-06 7,518E-04 ! neutral lipid catabolic process GO:0046461 13 8 2,000 1,15E-05 8,386E-04 ! glycerolipid catabolic process GO:0046503 13 8 2,000 1,15E-05 8,139E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 1,15E-05 7,906E-04 ! positive regulation of epidermis development GO:0045684 13 8 2,000 1,15E-05 7,687E-04 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 2,000 1,15E-05 7,479E-04 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 1,194E-05 7,561E-04 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 1,665E-05 1,027E-03 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 3,000 1,665E-05 1,001E-03 ! amyloid precursor protein metabolic process GO:0042982 14 9 2,000 1,718E-05 1,008E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 2,443E-05 1,399E-03 ! L-serine metabolic process GO:0006563 18 10 2,000 2,443E-05 1,367E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 2,000 2,443E-05 1,336E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 3,000 2,608E-05 1,394E-03 ! establishment of organelle localization GO:0051656 109 59 4,000 2,781E-05 1,454E-03 ! cell cycle arrest GO:0007050 213 100 5,000 3,139E-05 1,607E-03 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 2,000 3,344E-05 1,676E-03 ! nucleus localization GO:0051647 19 11 2,000 3,344E-05 1,642E-03 ! regulation of lipid metabolic process GO:0019216 115 63 4,000 3,829E-05 1,843E-03 ! positive regulation of cell motion GO:0051272 146 64 4,000 4,134E-05 1,95E-03 ! regulation of B cell proliferation GO:0030888 20 12 2,000 4,439E-05 2,054E-03 ! regulation of cell projection assembly GO:0060491 30 12 2,000 4,439E-05 2,015E-03 ! membrane protein proteolysis GO:0033619 25 12 2,000 4,439E-05 1,978E-03 GO:0006509|membrane protein ectodomain proteolysis, ! myeloid cell differentiation GO:0030099 111 65 4,000 4,457E-05 1,95E-03 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 3,000 4,974E-05 2,137E-03 ! regulation of epidermis development GO:0045682 19 13 2,000 5,746E-05 2,425E-03 ! serine family amino acid biosynthetic process GO:0009070 17 13 2,000 5,746E-05 2,384E-03 ! DNA integrity checkpoint GO:0031570 75 36 3,000 6,26E-05 2,553E-03 ! hormone biosynthetic process GO:0042446 57 36 3,000 6,26E-05 2,51E-03 ! meiosis I GO:0007127 65 37 3,000 6,986E-05 2,755E-03 ! regulation of protein stability GO:0031647 73 37 3,000 6,986E-05 2,711E-03 ! tRNA modification GO:0006400 20 14 2,000 7,281E-05 2,781E-03 ! carbohydrate homeostasis GO:0033500 53 38 3,000 7,771E-05 2,922E-03 GO:0042593|glucose homeostasis, ! meiosis GO:0007126 121 74 4,000 8,323E-05 3,081E-03 GO:0051327|M phase of meiotic cell cycle, ! organelle localization GO:0051640 136 74 4,000 8,323E-05 3,034E-03 ! meiotic cell cycle GO:0051321 122 75 4,000 8,874E-05 3,187E-03 ! glycoprotein catabolic process GO:0006516 26 15 2,000 9,061E-05 3,206E-03 ! negative regulation of binding GO:0051100 72 40 3,000 9,532E-05 3,324E-03 ! ribonucleoside metabolic process GO:0009119 55 40 3,000 9,532E-05 3,276E-03 ! filopodium assembly GO:0046847 32 16 2,000 1,11E-04 3,762E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 1,269E-04 4,242E-03 ! response to hypoxia GO:0001666 171 81 4,000 1,28E-04 4,218E-03 ! negative regulation of cell cycle process GO:0010948 32 17 2,000 1,342E-04 4,364E-03 ! signal complex assembly GO:0007172 41 17 2,000 1,342E-04 4,306E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 2,000 1,342E-04 4,249E-03 ! microspike assembly GO:0030035 36 17 2,000 1,342E-04 4,194E-03 ! response to oxygen levels GO:0070482 176 83 4,000 1,436E-04 4,431E-03 ! negative regulation of growth GO:0045926 155 84 4,000 1,52E-04 4,629E-03 ! regulation of DNA binding GO:0051101 155 88 4,000 1,892E-04 5,691E-03 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 2,000 1,896E-04 5,632E-03 ! proximal/distal pattern formation GO:0009954 32 19 2,000 1,896E-04 5,563E-03 ! regulation of cell cycle process GO:0010564 149 90 4,000 2,102E-04 6,095E-03 ! regulation of cell projection organization GO:0031344 121 50 3,000 2,293E-04 6,568E-03 ! reciprocal meiotic recombination GO:0007131 39 21 2,000 2,58E-04 7,302E-03 ! leukocyte differentiation GO:0002521 202 96 4,000 2,841E-04 7,948E-03 ! response to UV GO:0009411 104 53 3,000 2,875E-04 7,951E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 2,974E-04 8,131E-03 ! cellular response to reactive oxygen species GO:0034614 31 22 2,000 2,974E-04 8,039E-03 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 2,000 2,974E-04 7,95E-03 ! protein stabilization GO:0050821 39 22 2,000 2,974E-04 7,863E-03 ! hormone metabolic process GO:0042445 157 97 4,000 2,981E-04 7,796E-03 ! negative regulation of protein ubiquitination GO:0031397 9 5 1,000 3,511E-04 9,082E-03 ! hemoglobin biosynthetic process GO:0042541 7 5 1,000 3,511E-04 8,986E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 3,511E-04 8,891E-03 ! negative regulation of cell-cell adhesion GO:0022408 12 5 1,000 3,511E-04 8,798E-03 ! lipoprotein particle clearance GO:0034381 10 5 1,000 3,511E-04 8,708E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 3,511E-04 8,619E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 3,511E-04 8,532E-03 ! microvillus organization GO:0032528 7 5 1,000 3,511E-04 8,446E-03 GO:0030033|microvillus assembly, ! mRNA transcription GO:0009299 9 5 1,000 3,511E-04 8,363E-03 ! positive regulation of transporter activity GO:0032411 8 5 1,000 3,511E-04 8,281E-03 GO:0032414|positive regulation of ion transmembrane transporter activity, ! lipoprotein catabolic process GO:0042159 11 5 1,000 3,511E-04 8,2E-03 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 1,000 3,511E-04 8,122E-03 ! cellular glucose homeostasis GO:0001678 5 5 1,000 3,511E-04 8,044E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 3,511E-04 7,968E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 3,511E-04 7,894E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 3,511E-04 7,821E-03 ! cellular response to nutrient GO:0031670 8 5 1,000 3,511E-04 7,749E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 3,511E-04 7,679E-03 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 1,000 3,511E-04 7,609E-03 GO:0022011|myelination in the peripheral nervous system, ! stem cell division GO:0017145 11 5 1,000 3,511E-04 7,541E-03 GO:0048103|somatic stem cell division, ! positive regulation of cell migration GO:0030335 126 57 3,000 3,807E-04 8,106E-03 ! vasculogenesis GO:0001570 46 25 2,000 4,383E-04 9,251E-03 ! negative regulation of DNA replication GO:0008156 42 25 2,000 4,383E-04 9,17E-03 ! cellular response to nutrient levels GO:0031669 41 25 2,000 4,383E-04 9,091E-03 ! nucleoside metabolic process GO:0009116 81 60 3,000 4,635E-04 9,531E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 4,933E-04 0,01005871 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 4,933E-04 9,974E-03 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 5,245E-04 0,01051643 ! male meiosis GO:0007140 7 6 1,000 5,245E-04 0,01042951 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 1,000 5,245E-04 0,01034403 ! embryonic hemopoiesis GO:0035162 14 6 1,000 5,245E-04 0,01025993 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 1,000 5,245E-04 0,01017719 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 5,245E-04 0,01009577 ! positive regulation of exocytosis GO:0045921 8 6 1,000 5,245E-04 0,01001565 ! establishment of spindle localization GO:0051293 12 6 1,000 5,245E-04 9,937E-03 GO:0051653|spindle localization, ! astrocyte development GO:0014002 15 6 1,000 5,245E-04 9,859E-03 ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 5,245E-04 9,783E-03 ! Schwann cell development GO:0014044 15 6 1,000 5,245E-04 9,707E-03 ! negative regulation of B cell activation GO:0050869 13 6 1,000 5,245E-04 9,633E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 5,526E-04 0,01007154 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 5,526E-04 9,996E-03 ! embryonic limb morphogenesis GO:0030326 125 65 3,000 6,287E-04 0,01128881 GO:0035113|embryonic appendage morphogenesis, ! actin filament organization GO:0007015 148 66 3,000 6,662E-04 0,01187293 ! cell projection assembly GO:0030031 120 66 3,000 6,662E-04 0,01178563 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 6,842E-04 0,01201657 ! cellular hormone metabolic process GO:0034754 113 67 3,000 7,052E-04 0,01229514 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 7,052E-04 0,01220669 ! negative regulation of cell growth GO:0030308 132 67 3,000 7,052E-04 0,0121195 ! lung development GO:0030324 144 67 3,000 7,052E-04 0,01203354 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 7,314E-04 0,01239304 ! mRNA stabilization GO:0048255 18 7 1,000 7,314E-04 0,01230637 GO:0043489|RNA stabilization, ! lipoprotein transport GO:0042953 14 7 1,000 7,314E-04 0,01222091 ! spindle checkpoint GO:0031577 15 7 1,000 7,314E-04 0,01213663 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 1,000 7,314E-04 0,0120535 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 7,314E-04 0,0119715 ! oxygen homeostasis GO:0032364 12 7 1,000 7,314E-04 0,01189062 ! negative regulation of nuclear division GO:0051784 14 7 1,000 7,314E-04 0,01181081 GO:0045839|negative regulation of mitosis, ! negative regulation of kinase activity GO:0033673 131 68 3,000 7,458E-04 0,01196293 ! regulation of B cell activation GO:0050864 50 30 2,000 7,569E-04 0,01206081 ! negative regulation of cell size GO:0045792 134 69 3,000 7,881E-04 0,01247407 ! urogenital system development GO:0001655 137 69 3,000 7,881E-04 0,01239254 ! appendage morphogenesis GO:0035107 135 70 3,000 8,32E-04 0,0129979 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 3,000 8,32E-04 0,01291404 ! triglyceride metabolic process GO:0006641 43 31 2,000 8,344E-04 0,0128685 ! serine family amino acid metabolic process GO:0009069 49 31 2,000 8,344E-04 0,01278653 ! negative regulation of transcription regulator activity GO:0090048 58 31 2,000 8,344E-04 0,01270561 GO:0043433|negative regulation of transcription factor activity, ! reproductive structure development GO:0048608 113 71 3,000 8,775E-04 0,0132791 ! appendage development GO:0048736 136 71 3,000 8,775E-04 0,0131961 GO:0060173|limb development, ! negative regulation of transferase activity GO:0051348 140 72 3,000 9,249E-04 0,0138214 ! respiratory system development GO:0060541 153 72 3,000 9,249E-04 0,01373608 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 9,714E-04 0,01433859 ! T-helper 1 type immune response GO:0042088 12 8 1,000 9,714E-04 0,01425116 ! hemoglobin metabolic process GO:0020027 13 8 1,000 9,714E-04 0,01416479 ! astrocyte differentiation GO:0048708 18 8 1,000 9,714E-04 0,01407946 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 9,714E-04 0,01399515 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 9,714E-04 0,01391185 ! regulation of vascular permeability GO:0043114 12 8 1,000 9,714E-04 0,01382953 ! Schwann cell differentiation GO:0014037 19 8 1,000 9,714E-04 0,01374818 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 9,714E-04 0,01366778 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 9,714E-04 0,01358832 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 9,714E-04 0,01350977 ! mast cell activation GO:0045576 14 8 1,000 9,714E-04 0,01343213 ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 1,000 9,714E-04 0,01335537 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 1,000 9,714E-04 0,01327949 ! negative regulation of DNA replication initiation GO:0032297 9 8 1,000 9,714E-04 0,01320447 GO:0000076|DNA replication checkpoint, ! DNA damage checkpoint GO:0000077 71 33 2,000 1,004E-03 0,01356968 ! regulation of transcription factor activity GO:0051090 126 74 3,000 1,025E-03 0,0137756 GO:0090046|regulation of transcription regulator activity, ! steroid biosynthetic process GO:0006694 131 76 3,000 1,132E-03 0,01513404 ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 1,194E-03 0,01586869 ! negative regulation of cell adhesion GO:0007162 81 35 2,000 1,194E-03 0,0157815 ! neutral lipid metabolic process GO:0006638 50 35 2,000 1,194E-03 0,01569526 GO:0006639|acylglycerol metabolic process, ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,244E-03 0,01626713 ! cell proliferation in forebrain GO:0021846 15 9 1,000 1,244E-03 0,0161792 ! induction of positive chemotaxis GO:0050930 15 9 1,000 1,244E-03 0,01609221 ! artery development GO:0060840 24 9 1,000 1,244E-03 0,01600616 GO:0048844|artery morphogenesis, ! regulation of glycolysis GO:0006110 21 9 1,000 1,244E-03 0,01592102 ! cerebral cortex cell migration GO:0021795 15 9 1,000 1,244E-03 0,01583678 ! microtubule bundle formation GO:0001578 21 9 1,000 1,244E-03 0,01575343 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 1,000 1,244E-03 0,01567095 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,244E-03 0,01558933 ! receptor clustering GO:0043113 18 9 1,000 1,244E-03 0,01550856 ! protein heterooligomerization GO:0051291 16 9 1,000 1,244E-03 0,01542862 ! gas homeostasis GO:0033483 16 9 1,000 1,244E-03 0,0153495 ! postreplication repair GO:0006301 22 9 1,000 1,244E-03 0,01527118 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 1,244E-03 0,01519366 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 1,244E-03 0,01511693 ! negative regulation of organelle organization GO:0010639 161 78 3,000 1,247E-03 0,01507948 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 1,297E-03 0,01559826 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 1,405E-03 0,01681635 ! tissue remodeling GO:0048771 76 37 2,000 1,405E-03 0,0167331 ! negative regulation of DNA binding GO:0043392 68 37 2,000 1,405E-03 0,01665067 ! glycerol ether metabolic process GO:0006662 53 37 2,000 1,405E-03 0,01656905 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 1,405E-03 0,01648822 ! mitotic cell cycle checkpoint GO:0007093 76 38 2,000 1,519E-03 0,0177368 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,549E-03 0,0180036 ! lung alveolus development GO:0048286 26 10 1,000 1,549E-03 0,01791705 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 1,549E-03 0,01783132 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 1,549E-03 0,01774641 ! epithelial cell development GO:0002064 20 10 1,000 1,549E-03 0,0176623 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 1,000 1,549E-03 0,01757899 ! regulation of bone resorption GO:0045124 25 10 1,000 1,549E-03 0,01749646 ! regulation of DNA replication initiation GO:0030174 14 10 1,000 1,549E-03 0,0174147 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,549E-03 0,0173337 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,549E-03 0,01725345 GO:0043470|regulation of carbohydrate catabolic process, ! organic ether metabolic process GO:0018904 55 39 2,000 1,638E-03 0,0181612 ! RNA modification GO:0009451 57 39 2,000 1,638E-03 0,0180779 ! cytokinesis GO:0000910 72 40 2,000 1,763E-03 0,01936952 ! negative regulation of muscle development GO:0048635 20 11 1,000 1,886E-03 0,02062287 ! telencephalon cell migration GO:0022029 20 11 1,000 1,886E-03 0,02052955 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,886E-03 0,02043707 ! blood vessel remodeling GO:0001974 29 11 1,000 1,886E-03 0,02034543 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,886E-03 0,0202546 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,886E-03 0,02016458 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 1,000 1,886E-03 0,02007536 ! DNA methylation GO:0006306 19 11 1,000 1,886E-03 0,01998692 GO:0006305|DNA alkylation, ! regulation of leukocyte migration GO:0002685 26 11 1,000 1,886E-03 0,01989926 ! T cell receptor signaling pathway GO:0050852 23 11 1,000 1,886E-03 0,01981236 ! gland development GO:0048732 206 88 3,000 1,947E-03 0,02036573 ! response to reactive oxygen species GO:0000302 67 42 2,000 2,031E-03 0,02115135 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 2,031E-03 0,02106018 ! epithelial cell differentiation GO:0030855 79 43 2,000 2,174E-03 0,02244422 ! positive regulation of response to external stimulus GO:0032103 77 43 2,000 2,174E-03 0,0223483 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 2,254E-03 0,02307691 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 2,254E-03 0,02297913 GO:0050927|positive regulation of positive chemotaxis, ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,254E-03 0,02288217 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,254E-03 0,02278603 ! forebrain cell migration GO:0021885 21 12 1,000 2,254E-03 0,02269069 ! entry into host cell GO:0030260 32 12 1,000 2,254E-03 0,02259614 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! synaptic vesicle exocytosis GO:0016079 19 12 1,000 2,254E-03 0,02250238 ! histone acetylation GO:0016573 26 12 1,000 2,254E-03 0,0224094 ! regulation of hormone metabolic process GO:0032350 26 12 1,000 2,254E-03 0,02231718 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,254E-03 0,02222571 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 2,254E-03 0,022135 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 2,254E-03 0,02204502 ! response to cold GO:0009409 17 12 1,000 2,254E-03 0,02195577 ! regulation of steroid biosynthetic process GO:0050810 17 12 1,000 2,254E-03 0,02186723 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 2,477E-03 0,02393859 ! response to insulin stimulus GO:0032868 95 46 2,000 2,639E-03 0,02539515 ! regulation of chemokine production GO:0032642 18 13 1,000 2,653E-03 0,02543407 ! regulation of cell-cell adhesion GO:0022407 33 13 1,000 2,653E-03 0,02533314 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 2,653E-03 0,02523301 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,653E-03 0,02513367 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 33 13 1,000 2,653E-03 0,02503511 ! regulation of mRNA stability GO:0043488 31 13 1,000 2,653E-03 0,02493731 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 2,653E-03 0,02484028 ! embryonic placenta development GO:0001892 23 13 1,000 2,653E-03 0,024744 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 2,653E-03 0,02464846 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 3,000 2,673E-03 0,02473499 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 3,000 2,775E-03 0,02558182 ! positive regulation of DNA binding GO:0043388 73 47 2,000 2,806E-03 0,02577145 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 3,000 2,88E-03 0,0263459 ! positive regulation of cell cycle GO:0045787 89 48 2,000 2,98E-03 0,02716248 ! Notch signaling pathway GO:0007219 96 48 2,000 2,98E-03 0,02705998 ! cellular component disassembly GO:0022411 86 48 2,000 2,98E-03 0,02695825 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 2,98E-03 0,02685729 ! rRNA transcription GO:0009303 25 14 1,000 3,083E-03 0,0276819 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 3,083E-03 0,02757899 ! pteridine and derivative biosynthetic process GO:0042559 19 14 1,000 3,083E-03 0,02747684 ! regulation of S phase GO:0033261 23 14 1,000 3,083E-03 0,02737545 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 3,083E-03 0,02727481 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 3,083E-03 0,0271749 ! intestinal absorption GO:0050892 25 14 1,000 3,083E-03 0,02707572 ! regulation of RNA stability GO:0043487 32 14 1,000 3,083E-03 0,02697727 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 3,542E-03 0,03087598 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of binding GO:0051099 78 51 2,000 3,542E-03 0,03076452 ! cellular amino acid biosynthetic process GO:0008652 75 51 2,000 3,542E-03 0,03065385 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 3,544E-03 0,03056113 ! regulation of transmembrane transporter activity GO:0022898 27 15 1,000 3,544E-03 0,03045198 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! pituitary gland development GO:0021983 29 15 1,000 3,544E-03 0,03034361 ! regulation of exocytosis GO:0017157 22 15 1,000 3,544E-03 0,03023601 ! G1/S transition checkpoint GO:0031575 40 15 1,000 3,544E-03 0,03012917 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 3,544E-03 0,03002308 ! muscle maintenance GO:0046716 26 15 1,000 3,544E-03 0,02991773 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 3,544E-03 0,02981313 ! regulation of protein ubiquitination GO:0031396 25 16 1,000 4,034E-03 0,03382046 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 4,034E-03 0,03370302 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 4,034E-03 0,0335864 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 4,034E-03 0,03347059 GO:0031114|regulation of microtubule depolymerization, ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 4,034E-03 0,03335557 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 4,034E-03 0,03324134 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 4,034E-03 0,03312789 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of cell motion GO:0051271 134 55 2,000 4,385E-03 0,03588468 ! glial cell development GO:0021782 27 17 1,000 4,554E-03 0,03714443 ! limbic system development GO:0021761 36 17 1,000 4,554E-03 0,03701894 ! heart looping GO:0001947 30 17 1,000 4,554E-03 0,0368943 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 4,554E-03 0,03677049 ! regulation of protein binding GO:0043393 33 17 1,000 4,554E-03 0,03664751 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 4,554E-03 0,03652535 ! neural crest cell migration GO:0001755 37 17 1,000 4,554E-03 0,03640401 ! aromatic compound biosynthetic process GO:0019438 24 17 1,000 4,554E-03 0,03628346 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 4,554E-03 0,03616372 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 1,000 4,554E-03 0,03604476 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 4,554E-03 0,03592658 ! regulation of DNA replication GO:0006275 101 56 2,000 4,613E-03 0,03627072 ! regulation of lipid biosynthetic process GO:0046890 25 18 1,000 5,104E-03 0,03999699 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 5,104E-03 0,03986713 ! memory GO:0007613 31 18 1,000 5,104E-03 0,03973811 ! regulation of steroid metabolic process GO:0019218 30 18 1,000 5,104E-03 0,03960992 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 5,104E-03 0,03948256 ! cytokine-mediated signaling pathway GO:0019221 97 59 2,000 5,34E-03 0,04117785 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 5,596E-03 0,04301911 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 5,682E-03 0,04353505 ! lipid phosphorylation GO:0046834 35 19 1,000 5,682E-03 0,04339684 ! forelimb morphogenesis GO:0035136 32 19 1,000 5,682E-03 0,04325951 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 5,682E-03 0,04312305 ! cerebral cortex development GO:0021987 36 19 1,000 5,682E-03 0,04298744 ! pigmentation during development GO:0048066 41 19 1,000 5,682E-03 0,04285268 ! cellular response to unfolded protein GO:0034620 33 19 1,000 5,682E-03 0,04271877 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 42 19 1,000 5,682E-03 0,04258569 ! neuromuscular junction development GO:0007528 34 19 1,000 5,682E-03 0,04245343 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 5,682E-03 0,042322 ! peptide cross-linking GO:0018149 37 19 1,000 5,682E-03 0,04219137 ! prostaglandin metabolic process GO:0006693 37 19 1,000 5,682E-03 0,04206156 GO:0006692|prostanoid metabolic process, ! G1 phase GO:0051318 40 19 1,000 5,682E-03 0,04193253 ! regulation of protein complex assembly GO:0043254 117 61 2,000 5,86E-03 0,04311929 ! tRNA processing GO:0008033 89 61 2,000 5,86E-03 0,04298783 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 5,86E-03 0,04285717 ! regulation of homeostatic process GO:0032844 134 62 2,000 6,132E-03 0,04470514 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 6,288E-03 0,04570854 ! pteridine and derivative metabolic process GO:0042558 29 20 1,000 6,288E-03 0,04557086 ! protein amino acid acetylation GO:0006473 39 20 1,000 6,288E-03 0,04543401 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 6,288E-03 0,04529798 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 6,288E-03 0,04516276 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 6,288E-03 0,04502835 ! cellular response to starvation GO:0009267 33 20 1,000 6,288E-03 0,04489473 ! diencephalon development GO:0021536 34 20 1,000 6,288E-03 0,04476191 ! negative regulation of T cell activation GO:0050868 40 20 1,000 6,288E-03 0,04462987 ! regulation of mitosis GO:0007088 105 63 2,000 6,41E-03 0,04536225 GO:0051783|regulation of nuclear division, ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 6,41E-03 0,04522922 ! hindlimb morphogenesis GO:0035137 43 21 1,000 6,923E-03 0,04870402 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 6,923E-03 0,04856203 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 6,923E-03 0,04842086 ! DNA modification GO:0006304 34 21 1,000 6,923E-03 0,04828051 ! positive regulation of locomotion GO:0040017 39 21 1,000 6,923E-03 0,04814097 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 35 21 1,000 6,923E-03 0,04800224 ! germ cell development GO:0007281 118 65 2,000 6,99E-03 0,0483274 ! regulation of chemotaxis GO:0050920 40 22 1,000 7,586E-03 0,05229486 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 7,586E-03 0,05214544 ! apoptotic nuclear changes GO:0030262 32 22 1,000 7,586E-03 0,05199688 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 7,586E-03 0,05184916 ! positive regulation of B cell activation GO:0050871 38 22 1,000 7,586E-03 0,05170228 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 7,586E-03 0,05155623 ! chromosome segregation GO:0007059 113 67 2,000 7,6E-03 0,0515077 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 7,916E-03 0,05350097 ! protein maturation by peptide bond cleavage GO:0051605 105 68 2,000 7,916E-03 0,05335111 ! visual behavior GO:0007632 42 23 1,000 8,276E-03 0,0556175 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 8,276E-03 0,05546258 GO:0010810|regulation of cell-substrate adhesion, ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 1,000 8,276E-03 0,05530852 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! vesicle targeting GO:0006903 43 23 1,000 8,276E-03 0,05515531 ! synaptic vesicle transport GO:0048489 46 23 1,000 8,276E-03 0,05500295 ! platelet activation GO:0030168 37 23 1,000 8,276E-03 0,05485142 ! negative regulation of catabolic process GO:0009895 50 23 1,000 8,276E-03 0,05470073 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 8,993E-03 0,05927787 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 8,993E-03 0,05911591 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 8,993E-03 0,05895483 ! regulation of transmembrane transport GO:0034762 38 24 1,000 8,993E-03 0,05879463 ! digestive system process GO:0022600 39 24 1,000 8,993E-03 0,0586353 ! regulation of behavior GO:0050795 43 24 1,000 8,993E-03 0,05847682 ! pallium development GO:0021543 49 24 1,000 8,993E-03 0,0583192 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 8,993E-03 0,05816243 ! learning or memory GO:0007611 147 73 2,000 9,614E-03 0,06201195 ! myelination GO:0042552 45 25 1,000 9,737E-03 0,06263676 ! sperm motility GO:0030317 31 25 1,000 9,737E-03 0,06246973 ! receptor metabolic process GO:0043112 46 25 1,000 9,737E-03 0,06230359 ! response to starvation GO:0042594 42 25 1,000 9,737E-03 0,06213832 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 9,737E-03 0,06197394 ! neural crest cell development GO:0014032 54 25 1,000 9,737E-03 0,06181042 GO:0014033|neural crest cell differentiation, ! interaction with host GO:0051701 62 25 1,000 9,737E-03 0,06164776 ! somitogenesis GO:0001756 43 25 1,000 9,737E-03 0,06148595 ! neural tube closure GO:0001843 49 25 1,000 9,737E-03 0,061325 GO:0060606|tube closure, ! eye development GO:0001654 143 74 2,000 9,977E-03 0,06267262 ! cell-matrix adhesion GO:0007160 163 75 2,000 0,01034735 0,06483264 ! regulation of vesicle-mediated transport GO:0060627 119 75 2,000 0,01034735 0,06466424 ! initiation of viral infection GO:0019059 57 26 1,000 0,01050682 0,06549072 ! tube lumen formation GO:0035148 50 26 1,000 0,01050682 0,06532149 ! macromolecular complex disassembly GO:0032984 53 26 1,000 0,01050682 0,06515314 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 0,01050682 0,06498565 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 0,01050682 0,06481902 ! positive regulation of nuclear division GO:0051785 40 26 1,000 0,01050682 0,06465324 GO:0045840|positive regulation of mitosis, ! regulation of catabolic process GO:0009894 161 76 2,000 0,01072606 0,06583391 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 0,01130316 0,06919953 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 0,01130316 0,0690239 ! protein amino acid acylation GO:0043543 55 27 1,000 0,01130316 0,06884915 ! fat cell differentiation GO:0045444 50 27 1,000 0,01130316 0,06867529 ! male gonad development GO:0008584 44 27 1,000 0,01130316 0,0685023 ! primary neural tube formation GO:0014020 51 27 1,000 0,01130316 0,06833019 ! regulation of chromosome organization GO:0033044 42 27 1,000 0,01130316 0,06815893 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 0,01130316 0,06798854 ! dendrite development GO:0016358 59 28 1,000 0,01212524 0,07275146 ! negative regulation of protein modification process GO:0031400 60 28 1,000 0,01212524 0,07257048 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 0,01212524 0,07239041 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,01212524 0,07221122 ! response to metal ion GO:0010038 140 80 2,000 0,01232058 0,07319339 ! cellular lipid catabolic process GO:0044242 134 80 2,000 0,01232058 0,07301311 ! cell-substrate adhesion GO:0031589 171 81 2,000 0,01273927 0,07530881 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01297273 0,07650092 ! immune response-activating signal transduction GO:0002757 47 29 1,000 0,01297273 0,07631388 GO:0002764|immune response-regulating signal transduction, ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 0,01297273 0,07612775 ! cholesterol metabolic process GO:0008203 136 82 2,000 0,01316603 0,07707413 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 0,01316603 0,07688706 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,01384528 0,08065798 ! ensheathment of neurons GO:0007272 57 30 1,000 0,01384528 0,08046316 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 0,01384528 0,08026927 ! neurotransmitter secretion GO:0007269 48 30 1,000 0,01384528 0,08007632 ! collagen metabolic process GO:0032963 45 31 1,000 0,01474259 0,08506154 ! cholesterol homeostasis GO:0042632 53 31 1,000 0,01474259 0,08485804 GO:0055092|sterol homeostasis, ! iron ion homeostasis GO:0055072 54 31 1,000 0,01474259 0,08465552 ! erythrocyte differentiation GO:0030218 55 31 1,000 0,01474259 0,08445396 ! myeloid leukocyte activation GO:0002274 49 31 1,000 0,01474259 0,08425335 ! amine biosynthetic process GO:0009309 138 86 2,000 0,01495417 0,08526002 ! response to inorganic substance GO:0010035 153 86 2,000 0,01495417 0,08505846 ! tube morphogenesis GO:0035239 176 86 2,000 0,01495417 0,08485785 ! cholesterol transport GO:0030301 56 32 1,000 0,01566432 0,08867845 ! spindle organization GO:0007051 46 32 1,000 0,01566432 0,08847029 ! metanephros development GO:0001656 74 32 1,000 0,01566432 0,0882631 ! regulation of axonogenesis GO:0050770 75 32 1,000 0,01566432 0,08805687 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01566432 0,08785161 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01566432 0,08764731 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,01566432 0,08744395 ! regulation of cell morphogenesis GO:0022604 215 89 2,000 0,01638092 0,09123261 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,01638092 0,09102191 ! post-embryonic development GO:0009791 69 33 1,000 0,01661015 0,09208298 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,01661015 0,0918713 ! sterol transport GO:0015918 57 33 1,000 0,01661015 0,09166059 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01661015 0,09145084 ! establishment of vesicle localization GO:0051650 61 33 1,000 0,01661015 0,09124204 ! sex differentiation GO:0007548 145 90 2,000 0,01687289 0,0924742 ! sterol metabolic process GO:0016125 152 91 2,000 0,01737308 0,09499916 ! glial cell differentiation GO:0010001 63 34 1,000 0,01757977 0,09591138 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,01757977 0,09569439 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 1,000 0,01757977 0,09547837 ! spermatid development GO:0007286 63 34 1,000 0,01757977 0,09526333 ! placenta development GO:0001890 53 34 1,000 0,01757977 0,09504925 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,01757977 0,09483614 ! positive regulation of endocytosis GO:0045807 50 34 1,000 0,01757977 0,09462398 ! regulation of muscle development GO:0048634 70 35 1,000 0,01857286 0,09974619 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,01857286 0,09952404 ! telencephalon development GO:0021537 68 35 1,000 0,01857286 0,09930287 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,01857286 0,09908269 ! neural tube formation GO:0001841 67 35 1,000 0,01857286 0,09886348 ! vesicle localization GO:0051648 64 35 1,000 0,01857286 0,09864524 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,01958911 0,10381363 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,01958911 0,10358547 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 1,000 0,01958911 0,10335831 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,01958911 0,10313214 ! embryonic organ development GO:0048568 57 36 1,000 0,01958911 0,10290696 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,01958911 0,10268277 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 0,02054722 0,10747091 ! sister chromatid segregation GO:0000819 58 37 1,000 0,02062821 0,10766044 ! spermatid differentiation GO:0048515 66 37 1,000 0,02062821 0,10742741 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,02167132 0,11261598 GO:0060538|skeletal muscle organ development, ! regulation of neuron projection development GO:0010975 91 38 1,000 0,02168985 0,11246935 ! nucleus organization GO:0006997 67 38 1,000 0,02168985 0,11222748 ! lipid homeostasis GO:0055088 67 38 1,000 0,02168985 0,11198665 ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,02168985 0,11174685 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,02168985 0,11150808 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,02168985 0,11127032 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 0,02168985 0,11103357 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,02277374 0,11633462 ! segmentation GO:0035282 67 39 1,000 0,02277374 0,11608815 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,02277374 0,11584272 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,02387956 0,12121144 ! mesenchymal cell development GO:0014031 87 40 1,000 0,02387956 0,12095626 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of protein location GO:0045185 91 40 1,000 0,02387956 0,12070215 ! gliogenesis GO:0042063 88 41 1,000 0,02500703 0,12613608 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,02500703 0,12587219 ! T cell differentiation GO:0030217 81 41 1,000 0,02500703 0,12560941 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,02500703 0,12534772 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,02500703 0,12508713 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02615584 0,13056215 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,02615584 0,13029183 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,02615584 0,13002263 ! neuron migration GO:0001764 79 42 1,000 0,02615584 0,12975455 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,02732571 0,13527914 ! neural tube development GO:0021915 77 43 1,000 0,02732571 0,13500136 ! heterocycle biosynthetic process GO:0018130 69 43 1,000 0,02732571 0,13472471 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,02851634 0,14030741 ! male sex differentiation GO:0046661 76 44 1,000 0,02851634 0,14002107 ! biopolymer methylation GO:0043414 84 44 1,000 0,02851634 0,1397359 ! maintenance of location in cell GO:0051651 97 44 1,000 0,02851634 0,13945188 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02953031 0,14411751 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02953031 0,14382577 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02953031 0,14353522 ! neuron fate determination GO:0048664 7 5 0,000 0,02953031 0,14324583 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02953031 0,14295761 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02953031 0,14267055 ! polyol transport GO:0015791 12 5 0,000 0,02953031 0,14238463 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02953031 0,14209986 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02953031 0,14181623 ! response to superoxide GO:0000303 10 5 0,000 0,02953031 0,14153373 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02953031 0,14125235 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02953031 0,14097209 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02953031 0,14069293 ! female meiosis GO:0007143 7 5 0,000 0,02953031 0,14041488 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02953031 0,14013793 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02953031 0,13986207 ! cobalt ion transport GO:0006824 11 5 0,000 0,02953031 0,13958729 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02953031 0,13931359 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02953031 0,13904096 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02953031 0,1387694 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02953031 0,13849889 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02953031 0,13822944 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02953031 0,13796103 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02953031 0,13769367 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02953031 0,13742733 GO:0006451|translational readthrough, ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02953031 0,13716203 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02953031 0,13689775 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02953031 0,13663448 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02953031 0,13637223 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02953031 0,13611098 ! negative chemotaxis GO:0050919 14 5 0,000 0,02953031 0,13585073 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02953031 0,13559147 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02953031 0,1353332 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02953031 0,13507592 ! behavioral response to pain GO:0048266 9 5 0,000 0,02953031 0,1348196 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02953031 0,13456426 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02953031 0,13430989 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02953031 0,13405647 ! micturition GO:0060073 9 5 0,000 0,02953031 0,13380401 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02953031 0,1335525 ! copulation GO:0007620 9 5 0,000 0,02953031 0,13330194 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02953031 0,13305231 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02953031 0,13280361 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02953031 0,13255584 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02953031 0,132309 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02953031 0,13206307 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02953031 0,13181805 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02953031 0,13157395 ! grooming behavior GO:0007625 6 5 0,000 0,02953031 0,13133074 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02953031 0,13108843 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02953031 0,13084702 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02953031 0,13060649 ! response to protozoan GO:0001562 10 5 0,000 0,02953031 0,13036685 ! lymph vessel development GO:0001945 10 5 0,000 0,02953031 0,13012808 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02953031 0,12989019 ! endochondral ossification GO:0001958 16 5 0,000 0,02953031 0,12965316 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02953031 0,129417 ! parathyroid gland development GO:0060017 13 5 0,000 0,02953031 0,12918169 ! anagen GO:0042640 6 5 0,000 0,02953031 0,12894724 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02953031 0,12871364 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02953031 0,12848089 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02953031 0,12824897 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02953031 0,12801789 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02953031 0,12778765 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02953031 0,12755823 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02953031 0,12732963 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02953031 0,12710185 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02953031 0,12687488 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02953031 0,12664872 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02953031 0,12642337 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02953031 0,12619881 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02953031 0,12597506 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02953031 0,12575209 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02953031 0,12552991 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02953031 0,12530852 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02953031 0,12508791 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02953031 0,12486807 ! histidine catabolic process GO:0006548 6 5 0,000 0,02953031 0,124649 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02953031 0,1244307 ! valine metabolic process GO:0006573 10 5 0,000 0,02953031 0,12421317 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02953031 0,12399639 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02953031 0,12378037 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02953031 0,1235651 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02953031 0,12335058 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02953031 0,1231368 ! polyol catabolic process GO:0046174 7 5 0,000 0,02953031 0,12292376 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02953031 0,12271145 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02953031 0,12249988 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02953031 0,12228904 ! muscle cell migration GO:0014812 8 5 0,000 0,02953031 0,12207892 ! mitochondrial fission GO:0000266 8 5 0,000 0,02953031 0,12186952 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02953031 0,12166084 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02953031 0,12145287 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02953031 0,12124562 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02953031 0,12103907 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02953031 0,12083322 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02953031 0,12062807 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02953031 0,12042361 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02953031 0,12021985 ! response to food GO:0032094 6 5 0,000 0,02953031 0,12001678 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02953031 0,11981439 ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02953031 0,11961268 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02953031 0,11941165 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02953031 0,11921129 ! regulation of phospholipase A2 activity GO:0032429 13 5 0,000 0,02953031 0,11901161 ! forebrain neuron development GO:0021884 13 5 0,000 0,02953031 0,11881259 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02953031 0,11861424 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02953031 0,11841655 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02953031 0,11821952 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02953031 0,11802314 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02953031 0,11782742 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02953031 0,11763234 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02953031 0,1174379 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02953031 0,11724411 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02953031 0,11705096 ! basic amino acid transport GO:0015802 11 5 0,000 0,02953031 0,11685844 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02953031 0,11666655 ! depyrimidination GO:0045008 10 5 0,000 0,02953031 0,1164753 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02953031 0,11628467 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02953031 0,11609466 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02953031 0,11590527 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02953031 0,1157165 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02953031 0,11552834 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02953031 0,1153408 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02953031 0,11515386 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02953031 0,11496753 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02953031 0,1147818 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02953031 0,11459666 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02953031 0,11441213 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02953031 0,11422819 ! response to arsenic GO:0046685 10 5 0,000 0,02953031 0,11404483 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02953031 0,11386207 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02953031 0,11367989 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02953031 0,11349829 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02953031 0,11331728 ! response to cadmium ion GO:0046686 7 5 0,000 0,02953031 0,11313683 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02953031 0,11295697 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02953031 0,11277767 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02953031 0,11259894 ! decidualization GO:0046697 11 5 0,000 0,02953031 0,11242078 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02953031 0,11224318 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02953031 0,11206614 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02953031 0,11188966 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02953031 0,11171373 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02953031 0,11153835 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02953031 0,11136353 ! neural tube patterning GO:0021532 7 5 0,000 0,02953031 0,11118925 ! embryonic cleavage GO:0040016 6 5 0,000 0,02953031 0,11101552 ! peroxisome fission GO:0016559 5 5 0,000 0,02953031 0,11084233 ! histone demethylation GO:0016577 10 5 0,000 0,02953031 0,11066968 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02953031 0,11049756 ! mitotic recombination GO:0006312 9 5 0,000 0,02953031 0,11032598 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02953031 0,11015493 ! metaphase plate congression GO:0051310 7 5 0,000 0,02953031 0,10998441 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02953031 0,10981442 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,02953031 0,10964496 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02953031 0,10947601 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02953031 0,10930759 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02953031 0,10913968 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02953031 0,10897229 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02953031 0,10880541 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02953031 0,10863904 ! plasminogen activation GO:0031639 5 5 0,000 0,02953031 0,10847318 ! B cell homeostasis GO:0001782 13 5 0,000 0,02953031 0,10830782 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02953031 0,10814297 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02953031 0,10797862 ! metaphase GO:0051323 8 5 0,000 0,02953031 0,10781477 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02953031 0,10765141 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02953031 0,10748855 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02953031 0,10732618 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02953031 0,1071643 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02953031 0,10700291 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02953031 0,106842 ! response to redox state GO:0051775 5 5 0,000 0,02953031 0,10668158 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02953031 0,10652164 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02953031 0,10636217 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02953031 0,10620319 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02953031 0,10604467 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02953031 0,10588663 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02953031 0,10572906 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02953031 0,10557196 ! striatum development GO:0021756 9 5 0,000 0,02953031 0,10541533 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02953031 0,10525916 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02953031 0,10510345 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02953031 0,1049482 ! glial cell migration GO:0008347 11 5 0,000 0,02953031 0,10479341 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02953031 0,10463907 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02953031 0,10448519 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02953031 0,10433176 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02953031 0,10417879 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02953031 0,10402625 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02953031 0,10387417 ! neuroprotection GO:0043526 6 5 0,000 0,02953031 0,10372253 ! neural plate development GO:0001840 8 5 0,000 0,02953031 0,10357133 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02953031 0,10342057 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02953031 0,10327025 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02953031 0,10312037 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02953031 0,10297092 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02953031 0,1028219 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02953031 0,10267331 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02953031 0,10252515 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02953031 0,10237742 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02953031 0,10223012 ! spindle assembly GO:0051225 6 5 0,000 0,02953031 0,10208324 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02953031 0,10193677 GO:0016226|iron-sulfur cluster assembly, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02953031 0,10179073 ! drug metabolic process GO:0017144 6 5 0,000 0,02953031 0,10164511 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02953031 0,1014999 ! organ regeneration GO:0031100 7 5 0,000 0,02953031 0,10135511 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02953031 0,10121073 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02953031 0,10106676 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02953031 0,1009232 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,02972746 0,10145285 ! ATP synthesis coupled electron transport GO:0042773 64 45 1,000 0,02972746 0,10130915 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 1,000 0,02972746 0,10116586 ! cell growth GO:0016049 84 45 1,000 0,02972746 0,10102297 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,03095876 0,10505893 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,03095876 0,10491096 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,03095876 0,10476341 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,03095876 0,10461627 ! pigmentation GO:0043473 100 46 1,000 0,03095876 0,10446954 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,03095876 0,10432323 ! positive regulation of defense response GO:0031349 76 47 1,000 0,03220998 0,10838771 ! response to calcium ion GO:0051592 81 47 1,000 0,03220998 0,10823633 ! endosome transport GO:0016197 108 47 1,000 0,03220998 0,10808537 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,03220998 0,10793484 ! methylation GO:0032259 90 47 1,000 0,03220998 0,10778472 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,03348083 0,11188178 ! activation of caspase activity GO:0006919 84 48 1,000 0,03348083 0,1117266 ! regulation of inflammatory response GO:0050727 75 48 1,000 0,03348083 0,11157185 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,03348083 0,11141754 ! regulation of action potential GO:0001508 95 49 1,000 0,03477104 0,11555126 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,03477104 0,11539188 ! response to temperature stimulus GO:0009266 76 49 1,000 0,03477104 0,11523294 ! unsaturated fatty acid metabolic process GO:0033559 86 49 1,000 0,03477104 0,11507444 ! endocrine system development GO:0035270 104 49 1,000 0,03477104 0,11491637 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,03477104 0,11475873 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03533147 0,11644866 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03533147 0,11628936 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03533147 0,1161305 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03533147 0,11597207 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03533147 0,11581406 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03533147 0,11565649 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03533147 0,11549935 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03533147 0,11534264 ! sleep GO:0030431 13 6 0,000 0,03533147 0,11518635 ! response to oxygen radical GO:0000305 11 6 0,000 0,03533147 0,11503048 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03533147 0,11487503 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03533147 0,11472 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03533147 0,1145654 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03533147 0,1144112 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03533147 0,11425742 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03533147 0,11410406 ! forebrain regionalization GO:0021871 8 6 0,000 0,03533147 0,1139511 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03533147 0,11379856 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03533147 0,11364642 ! response to zinc ion GO:0010043 9 6 0,000 0,03533147 0,11349469 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03533147 0,11334336 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03533147 0,11319244 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03533147 0,11304192 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03533147 0,1128918 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03533147 0,11274207 ! malate metabolic process GO:0006108 11 6 0,000 0,03533147 0,11259275 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03533147 0,11244381 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03533147 0,11229528 ! protein refolding GO:0042026 15 6 0,000 0,03533147 0,11214713 ! opsonization GO:0008228 8 6 0,000 0,03533147 0,11199937 ! mating behavior GO:0007617 7 6 0,000 0,03533147 0,111852 ! neuron remodeling GO:0016322 15 6 0,000 0,03533147 0,11170502 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03533147 0,11155843 ! equilibrioception GO:0050957 14 6 0,000 0,03533147 0,11141222 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03533147 0,11126639 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03533147 0,11112095 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03533147 0,11097588 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03533147 0,11083119 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03533147 0,11068688 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03533147 0,11054294 ! toxin metabolic process GO:0009404 11 6 0,000 0,03533147 0,11039938 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03533147 0,11025619 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03533147 0,11011337 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03533147 0,10997092 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03533147 0,10982884 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03533147 0,10968713 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03533147 0,10954578 ! thymic T cell selection GO:0045061 12 6 0,000 0,03533147 0,10940479 ! protein lipoylation GO:0009249 10 6 0,000 0,03533147 0,10926417 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03533147 0,10912391 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03533147 0,108984 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03533147 0,10884446 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03533147 0,10870527 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03533147 0,10856644 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03533147 0,10842796 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03533147 0,10828984 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03533147 0,10815207 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03533147 0,10801464 ! hyperosmotic response GO:0006972 9 6 0,000 0,03533147 0,10787757 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03533147 0,10774084 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03533147 0,10760446 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03533147 0,10746842 ! urea metabolic process GO:0019627 7 6 0,000 0,03533147 0,10733273 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03533147 0,10719738 ! neutrophil activation GO:0042119 8 6 0,000 0,03533147 0,10706237 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03533147 0,1069277 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03533147 0,10679337 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03533147 0,10665938 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03533147 0,10652572 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03533147 0,1063924 ! neuron apoptosis GO:0051402 9 6 0,000 0,03533147 0,1062594 ! nucleoside salvage GO:0043174 9 6 0,000 0,03533147 0,10612675 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03533147 0,10599442 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03533147 0,10586242 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03533147 0,10573075 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,03533147 0,10559941 ! carnitine transport GO:0015879 10 6 0,000 0,03533147 0,10546839 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03533147 0,1053377 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03533147 0,10520733 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03533147 0,10507729 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03533147 0,10494756 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03533147 0,10481815 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03533147 0,10468907 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03533147 0,1045603 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03533147 0,10443185 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03533147 0,10430371 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03533147 0,10417589 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03533147 0,10404838 ! neural nucleus development GO:0048857 14 6 0,000 0,03533147 0,10392118 ! response to UV-C GO:0010225 11 6 0,000 0,03533147 0,10379429 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03533147 0,10366771 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03533147 0,10354144 ! interaction with symbiont GO:0051702 13 6 0,000 0,03533147 0,10341548 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03533147 0,10328982 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03533147 0,10316447 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03533147 0,10303942 ! response to copper ion GO:0046688 10 6 0,000 0,03533147 0,10291468 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03533147 0,10279023 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03533147 0,10266609 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03533147 0,10254225 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03533147 0,1024187 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03533147 0,10229546 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03533147 0,1021725 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03533147 0,10204985 ! hair follicle maturation GO:0048820 7 6 0,000 0,03533147 0,10192749 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03533147 0,10180542 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03533147 0,10168364 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03533147 0,10156215 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03533147 0,10144096 ! subpallium development GO:0021544 10 6 0,000 0,03533147 0,10132005 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03533147 0,10119943 ! histone ubiquitination GO:0016574 8 6 0,000 0,03533147 0,1010791 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03533147 0,10095905 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03533147 0,10083929 ! G2 phase GO:0051319 16 6 0,000 0,03533147 0,10071981 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03533147 0,10060062 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03533147 0,10048171 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03533147 0,10036307 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03533147 0,10024472 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03533147 0,10012665 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03533147 0,10000885 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03533147 0,09989133 ! receptor internalization GO:0031623 10 6 0,000 0,03533147 0,09977409 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03533147 0,09965712 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03533147 0,09954043 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03533147 0,099424 ! protein deubiquitination GO:0016579 14 6 0,000 0,03533147 0,09930785 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03533147 0,09919198 ! protein destabilization GO:0031648 9 6 0,000 0,03533147 0,09907637 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03533147 0,09896103 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03533147 0,09884596 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03533147 0,09873115 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03533147 0,09861662 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03533147 0,09850234 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03533147 0,09838834 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03533147 0,09827459 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03533147 0,09816111 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03533147 0,09804789 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03533147 0,09793494 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03533147 0,09782224 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03533147 0,0977098 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03533147 0,09759762 ! catecholamine transport GO:0051937 9 6 0,000 0,03533147 0,09748569 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03533147 0,09737402 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03533147 0,09726261 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03533147 0,09715146 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03533147 0,09704055 ! maternal placenta development GO:0001893 12 6 0,000 0,03533147 0,0969299 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03533147 0,0968195 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03533147 0,09670936 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03533147 0,09659946 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03533147 0,09648981 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03533147 0,09638041 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03533147 0,09627126 ! histone modification GO:0016570 91 50 1,000 0,03608033 0,09820053 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,03608033 0,09808956 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,03608033 0,09797885 ! positive regulation of cytokine production GO:0001819 86 50 1,000 0,03608033 0,09786839 ! viral infectious cycle GO:0019058 99 51 1,000 0,03740843 0,10135661 ! excretion GO:0007588 83 51 1,000 0,03740843 0,1012426 ! regulation of cell shape GO:0008360 125 51 1,000 0,03740843 0,10112885 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,03740843 0,10101534 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,03875507 0,10453441 ! positive regulation of growth GO:0045927 90 52 1,000 0,03875507 0,10441735 ! covalent chromatin modification GO:0016569 101 52 1,000 0,03875507 0,10430055 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,03875507 0,10418401 ! cartilage development GO:0051216 90 52 1,000 0,03875507 0,10406774 ! synapse organization GO:0050808 85 52 1,000 0,03875507 0,10395172 ! respiratory electron transport chain GO:0022904 76 53 1,000 0,04011998 0,10749297 ! lipoprotein biosynthetic process GO:0042158 101 53 1,000 0,04011998 0,1073734 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 1,000 0,04011998 0,10725409 ! cell maturation GO:0048469 100 53 1,000 0,04011998 0,10713505 ! tRNA transcription GO:0009304 14 7 0,000 0,04109815 0,10962544 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04109815 0,10950403 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04109815 0,1093829 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04109815 0,10926204 ! regulation of helicase activity GO:0051095 15 7 0,000 0,04109815 0,10914144 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,04109815 0,10902111 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04109815 0,10890104 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04109815 0,10878123 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04109815 0,1086617 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04109815 0,10854242 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04109815 0,1084234 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04109815 0,10830465 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04109815 0,10818615 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04109815 0,10806792 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04109815 0,10794994 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04109815 0,10783222 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04109815 0,10771475 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04109815 0,10759754 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04109815 0,10748059 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04109815 0,10736389 ! glycolipid transport GO:0046836 10 7 0,000 0,04109815 0,10724744 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04109815 0,10713125 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,04109815 0,10701531 ! neuron adhesion GO:0007158 12 7 0,000 0,04109815 0,10689961 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04109815 0,10678417 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04109815 0,10666898 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04109815 0,10655403 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04109815 0,10643934 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04109815 0,10632488 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04109815 0,10621068 ! pericardium development GO:0060039 14 7 0,000 0,04109815 0,10609672 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04109815 0,105983 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04109815 0,10586953 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,04109815 0,1057563 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04109815 0,10564331 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,04109815 0,10553057 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04109815 0,10541806 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04109815 0,1053058 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04109815 0,10519377 ! rhythmic behavior GO:0007622 15 7 0,000 0,04109815 0,10508198 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04109815 0,10497043 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04109815 0,10485911 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04109815 0,10474803 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04109815 0,10463719 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04109815 0,10452658 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04109815 0,1044162 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04109815 0,10430606 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04109815 0,10419615 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04109815 0,10408647 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04109815 0,10397702 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04109815 0,1038678 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04109815 0,10375881 ! spinal cord patterning GO:0021511 13 7 0,000 0,04109815 0,10365004 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04109815 0,10354151 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04109815 0,1034332 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04109815 0,10332512 ! adrenal gland development GO:0030325 17 7 0,000 0,04109815 0,10321727 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04109815 0,10310964 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04109815 0,10300223 ! ovulation GO:0030728 9 7 0,000 0,04109815 0,10289505 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04109815 0,10278809 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04109815 0,10268135 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04109815 0,10257484 ! microtubule nucleation GO:0007020 20 7 0,000 0,04109815 0,10246854 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04109815 0,10236247 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04109815 0,10225661 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04109815 0,10215097 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04109815 0,10204555 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04109815 0,10194035 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04109815 0,10183537 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04109815 0,1017306 ! galactose metabolic process GO:0006012 13 7 0,000 0,04109815 0,10162605 ! vesicle fusion GO:0006906 17 7 0,000 0,04109815 0,10152171 ! response to dietary excess GO:0002021 8 7 0,000 0,04109815 0,10141758 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04109815 0,10131367 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04109815 0,10120997 GO:0045851|pH reduction, ! melanosome organization GO:0032438 9 7 0,000 0,04109815 0,10110649 ! organ growth GO:0035265 15 7 0,000 0,04109815 0,10100321 ! purine salvage GO:0043101 10 7 0,000 0,04109815 0,10090015 ! nucleoside transport GO:0015858 8 7 0,000 0,04109815 0,10079729 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04109815 0,10069465 ! parturition GO:0007567 14 7 0,000 0,04109815 0,10059221 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,04109815 0,10048998 ! rRNA modification GO:0000154 14 7 0,000 0,04109815 0,10038796 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04109815 0,10028615 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,04109815 0,10018454 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04109815 0,10008314 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04109815 0,09998194 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,04109815 0,09988095 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04109815 0,09978016 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,04109815 0,09967958 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04109815 0,0995792 ! fibrinolysis GO:0042730 10 7 0,000 0,04109815 0,09947902 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,04109815 0,09937904 ! eating behavior GO:0042755 7 7 0,000 0,04109815 0,09927926 ! B cell lineage commitment GO:0002326 21 7 0,000 0,04109815 0,09917968 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04109815 0,0990803 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04109815 0,09898112 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04109815 0,09888214 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04109815 0,09878336 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04109815 0,09868477 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04109815 0,09858638 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,04109815 0,09848819 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04109815 0,09839019 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04109815 0,09829239 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04109815 0,09819478 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04109815 0,09809736 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04109815 0,09800014 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04109815 0,09790311 ! regulation of meiosis GO:0040020 12 7 0,000 0,04109815 0,09780627 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04109815 0,09770963 ! T cell lineage commitment GO:0002360 16 7 0,000 0,04109815 0,09761317 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04109815 0,09751691 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04109815 0,09742083 ! transcription termination GO:0006353 13 7 0,000 0,04109815 0,09732494 ! response to tumor cell GO:0002347 13 7 0,000 0,04109815 0,09722925 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,04109815 0,09713374 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04109815 0,09703841 ! anaphase GO:0051322 17 7 0,000 0,04109815 0,09694328 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04109815 0,09684833 ! axonal fasciculation GO:0007413 18 7 0,000 0,04109815 0,09675356 ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04109815 0,09665899 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,04109815 0,09656459 ! diuresis GO:0030146 12 7 0,000 0,04109815 0,09647038 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04109815 0,09637636 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04109815 0,09628251 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04109815 0,09618885 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,04109815 0,09609538 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,04109815 0,09600208 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04109815 0,09590896 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04109815 0,09581603 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04109815 0,09572327 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04109815 0,0956307 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04109815 0,0955383 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04109815 0,09544608 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04109815 0,09535404 ! lymph node development GO:0048535 10 7 0,000 0,04109815 0,09526218 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04109815 0,09517049 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04109815 0,09507898 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04109815 0,09498765 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04109815 0,09489649 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04109815 0,09480551 ! adult feeding behavior GO:0008343 9 7 0,000 0,04109815 0,0947147 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04109815 0,09462406 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04109815 0,0945336 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04109815 0,09444331 ! muscle adaptation GO:0043500 14 7 0,000 0,04109815 0,09435319 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04109815 0,09426324 ! retina homeostasis GO:0001895 12 7 0,000 0,04109815 0,09417347 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04109815 0,09408387 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04109815 0,09399443 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04109815 0,09390517 ! protein prenylation GO:0018342 18 7 0,000 0,04109815 0,09381607 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04109815 0,09372715 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04109815 0,09363839 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04109815 0,0935498 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,04150291 0,09438186 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,04150291 0,09429274 ! cell recognition GO:0008037 85 54 1,000 0,04150291 0,09420378 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,04290359 0,09729128 GO:0010952|positive regulation of peptidase activity, ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,04290359 0,09719967 ! aging GO:0007568 103 55 1,000 0,04290359 0,09710823 ! heart morphogenesis GO:0003007 97 55 1,000 0,04290359 0,09701696 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,04290359 0,09692586 ! regulation of actin filament length GO:0030832 105 56 1,000 0,04432176 0,1000358 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,04432176 0,09994205 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,04432176 0,09984847 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,04575717 0,10298573 ! muscle fiber development GO:0048747 112 57 1,000 0,04575717 0,10288949 ! lipid modification GO:0030258 97 57 1,000 0,04575717 0,10279342 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,04575717 0,10269753 ! maintenance of location GO:0051235 118 57 1,000 0,04575717 0,10260182 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04683054 0,10491087 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04683054 0,10481328 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04683054 0,10471587 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04683054 0,10461864 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04683054 0,10452159 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04683054 0,10442473 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04683054 0,10432804 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04683054 0,10423152 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04683054 0,10413519 ! meiotic prophase I GO:0007128 13 8 0,000 0,04683054 0,10403904 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04683054 0,10394306 ! oligopeptide transport GO:0006857 15 8 0,000 0,04683054 0,10384726 ! signal peptide processing GO:0006465 12 8 0,000 0,04683054 0,10375164 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04683054 0,10365619 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04683054 0,10356092 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04683054 0,10346582 ! succinate metabolic process GO:0006105 14 8 0,000 0,04683054 0,1033709 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04683054 0,10327615 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04683054 0,10318157 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04683054 0,10308717 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04683054 0,10299294 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04683054 0,10289888 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04683054 0,102805 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04683054 0,10271128 ! reflex GO:0060004 16 8 0,000 0,04683054 0,10261774 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04683054 0,10252437 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04683054 0,10243116 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04683054 0,10233813 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04683054 0,10224526 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04683054 0,10215256 ! pigment granule organization GO:0048753 16 8 0,000 0,04683054 0,10206003 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04683054 0,10196767 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04683054 0,10187548 ! histidine metabolic process GO:0006547 16 8 0,000 0,04683054 0,10178345 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04683054 0,10169159 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04683054 0,10159989 ! glycine catabolic process GO:0006546 13 8 0,000 0,04683054 0,10150836 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04683054 0,10141699 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04683054 0,10132579 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,04683054 0,10123475 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04683054 0,10114388 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04683054 0,10105316 ! melanin metabolic process GO:0006582 15 8 0,000 0,04683054 0,10096262 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04683054 0,10087223 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04683054 0,100782 ! macrophage activation GO:0042116 12 8 0,000 0,04683054 0,10069194 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04683054 0,10060203 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04683054 0,10051229 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04683054 0,10042271 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04683054 0,10033328 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04683054 0,10024402 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04683054 0,10015491 ! osteoblast development GO:0002076 16 8 0,000 0,04683054 0,10006597 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04683054 0,09997718 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04683054 0,09988854 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04683054 0,09980007 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04683054 0,09971175 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04683054 0,09962359 ! response to UV-B GO:0010224 16 8 0,000 0,04683054 0,09953558 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04683054 0,09944773 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04683054 0,09936003 ! intermediate filament organization GO:0045109 12 8 0,000 0,04683054 0,09927249 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04683054 0,0991851 ! cellular extravasation GO:0045123 12 8 0,000 0,04683054 0,09909787 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04683054 0,09901079 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04683054 0,09892386 ! response to antibiotic GO:0046677 11 8 0,000 0,04683054 0,09883709 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04683054 0,09875046 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04683054 0,09866399 ! DNA topological change GO:0006265 12 8 0,000 0,04683054 0,09857767 ! response to tropane GO:0014073 15 8 0,000 0,04683054 0,0984915 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04683054 0,09840548 ! melanosome transport GO:0032402 13 8 0,000 0,04683054 0,09831961 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04683054 0,0982339 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04683054 0,09814833 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04683054 0,09806291 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04683054 0,09797763 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04683054 0,09789251 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04683054 0,09780753 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04683054 0,0977227 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04683054 0,09763802 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04683054 0,09755349 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04683054 0,0974691 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04683054 0,09738486 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04683054 0,09730076 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04683054 0,09721681 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04683054 0,097133 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04683054 0,09704934 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04683054 0,09696582 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04683054 0,09688244 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04683054 0,09679921 ! hormone catabolic process GO:0042447 17 8 0,000 0,04683054 0,09671612 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04683054 0,09663317 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04683054 0,09655037 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04683054 0,0964677 ! ATP catabolic process GO:0006200 11 8 0,000 0,04683054 0,09638518 ! blastocyst growth GO:0001832 19 8 0,000 0,04683054 0,0963028 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04683054 0,09622056 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04683054 0,09613846 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04683054 0,0960565 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04683054 0,09597468 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04683054 0,095893 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04683054 0,09581146 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04683054 0,09573006 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04683054 0,09564879 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04683054 0,09556767 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04683054 0,09548668 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04683054 0,09540582 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04683054 0,09532511 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04683054 0,09524453 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04683054 0,09516409 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,04720956 0,09585333 ! regulation of endocytosis GO:0030100 91 58 1,000 0,04720956 0,0957725 ! positive regulation of secretion GO:0051047 95 59 1,000 0,04867867 0,09866966 ! regulation of cellular component size GO:0032535 109 59 1,000 0,04867867 0,0985866 ! regulation of Rab protein signal transduction GO:0032483 92 59 1,000 0,04867867 0,09850369 GO:0032313|regulation of Rab GTPase activity, ! DNA catabolic process GO:0006308 86 59 1,000 0,04867867 0,09842091 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,04867867 0,09833827 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 0,05016427 0,10125438 ! camera-type eye development GO:0043010 116 60 1,000 0,05016427 0,10116951 ! kidney development GO:0001822 122 60 1,000 0,05016427 0,10108478 ! regulation of developmental growth GO:0048638 15 9 0,000 0,05252885 0,10576102 ! axon extension GO:0048675 15 9 0,000 0,05252885 0,10567259 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05252885 0,10558431 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05252885 0,10549618 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05252885 0,10540819 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05252885 0,10532035 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05252885 0,10523266 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05252885 0,10514511 ! phosphate transport GO:0006817 19 9 0,000 0,05252885 0,10505771 ! reproductive behavior GO:0019098 19 9 0,000 0,05252885 0,10497045 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05252885 0,10488334 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05252885 0,10479637 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05252885 0,10470954 ! RNA methylation GO:0001510 15 9 0,000 0,05252885 0,10462286 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05252885 0,10453633 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05252885 0,10444993 ! regulation of histone modification GO:0031056 12 9 0,000 0,05252885 0,10436368 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05252885 0,10427757 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05252885 0,10419161 ! chemosensory behavior GO:0007635 20 9 0,000 0,05252885 0,10410578 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,05252885 0,1040201 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05252885 0,10393456 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05252885 0,10384915 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05252885 0,10376389 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05252885 0,10367877 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05252885 0,10359379 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05252885 0,10350894 ! protein targeting to ER GO:0045047 22 9 0,000 0,05252885 0,10342424 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05252885 0,10333967 ! T cell selection GO:0045058 23 9 0,000 0,05252885 0,10325524 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05252885 0,10317095 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05252885 0,1030868 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05252885 0,10300279 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05252885 0,10291891 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05252885 0,10283517 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05252885 0,10275156 ! mannose metabolic process GO:0006013 13 9 0,000 0,05252885 0,10266809 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05252885 0,10258476 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05252885 0,10250156 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05252885 0,10241849 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05252885 0,10233556 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05252885 0,10225277 ! ruffle organization GO:0031529 15 9 0,000 0,05252885 0,1021701 ! retinol metabolic process GO:0042572 18 9 0,000 0,05252885 0,10208758 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05252885 0,10200518 ! behavioral fear response GO:0001662 22 9 0,000 0,05252885 0,10192292 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05252885 0,10184079 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05252885 0,10175879 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05252885 0,10167693 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,05252885 0,10159519 ! oligodendrocyte development GO:0014003 10 9 0,000 0,05252885 0,10151359 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,05252885 0,10143212 ! segment specification GO:0007379 13 9 0,000 0,05252885 0,10135078 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05252885 0,10126957 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05252885 0,10118849 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05252885 0,10110754 ! response to amine stimulus GO:0014075 13 9 0,000 0,05252885 0,10102671 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05252885 0,10094602 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05252885 0,10086546 ! erythrocyte development GO:0048821 15 9 0,000 0,05252885 0,10078502 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05252885 0,10070472 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,05252885 0,10062454 ! renal water homeostasis GO:0003091 14 9 0,000 0,05252885 0,10054449 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05252885 0,10046456 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05252885 0,10038477 ! icosanoid secretion GO:0032309 15 9 0,000 0,05252885 0,10030509 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05252885 0,10022555 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05252885 0,10014613 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05252885 0,10006684 ! regulation of cell division GO:0051302 15 9 0,000 0,05252885 0,09998767 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05252885 0,09990863 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05252885 0,09982972 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05252885 0,09975092 ! sterol catabolic process GO:0016127 11 9 0,000 0,05252885 0,09967225 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05252885 0,09959371 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05252885 0,09951529 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05252885 0,09943699 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05252885 0,09935882 GO:0000084|S phase of mitotic cell cycle, ! musculoskeletal movement GO:0050881 14 9 0,000 0,05252885 0,09928077 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05252885 0,09920284 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05252885 0,09912503 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05252885 0,09904735 ! purine base metabolic process GO:0006144 21 9 0,000 0,05252885 0,09896979 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05252885 0,09889235 ! pigment granule transport GO:0051904 17 9 0,000 0,05252885 0,09881503 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05252885 0,09873783 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,05252885 0,09866075 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05252885 0,09858379 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05252885 0,09850695 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05252885 0,09843023 ! mitochondrion localization GO:0051646 15 9 0,000 0,05252885 0,09835363 ! viral reproductive process GO:0022415 126 62 1,000 0,05318391 0,09950271 ! gonad development GO:0008406 98 62 1,000 0,05318391 0,0994254 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,05819329 0,10870578 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05819329 0,10862145 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05819329 0,10853725 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05819329 0,10845318 ! synapsis GO:0007129 13 10 0,000 0,05819329 0,10836923 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05819329 0,10828542 ! N-glycan processing GO:0006491 20 10 0,000 0,05819329 0,10820174 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05819329 0,10811819 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,05819329 0,10803476 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,05819329 0,10795146 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05819329 0,1078683 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05819329 0,10778526 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,05819329 0,10770235 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05819329 0,10761956 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05819329 0,1075369 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05819329 0,10745437 ! androgen metabolic process GO:0008209 17 10 0,000 0,05819329 0,10737197 ! phospholipid efflux GO:0033700 16 10 0,000 0,05819329 0,10728969 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05819329 0,10720754 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05819329 0,10712552 ! pathogenesis GO:0009405 13 10 0,000 0,05819329 0,10704362 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05819329 0,10696184 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05819329 0,10688019 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05819329 0,10679866 ! endoderm development GO:0007492 16 10 0,000 0,05819329 0,10671726 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05819329 0,10663599 ! arginine catabolic process GO:0006527 13 10 0,000 0,05819329 0,10655483 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05819329 0,1064738 ! proline metabolic process GO:0006560 13 10 0,000 0,05819329 0,10639289 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05819329 0,10631211 GO:0005978|glycogen biosynthetic process, ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05819329 0,10623145 ! V(D)J recombination GO:0033151 28 10 0,000 0,05819329 0,10615091 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05819329 0,10607049 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05819329 0,1059902 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05819329 0,10591002 ! B cell proliferation GO:0042100 18 10 0,000 0,05819329 0,10582997 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05819329 0,10575004 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05819329 0,10567023 ! multicellular organism growth GO:0035264 18 10 0,000 0,05819329 0,10559054 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05819329 0,10551096 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05819329 0,10543151 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05819329 0,10535218 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05819329 0,10527297 ! macroautophagy GO:0016236 17 10 0,000 0,05819329 0,10519388 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05819329 0,1051149 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05819329 0,10503605 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05819329 0,10495731 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,05819329 0,10487869 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05819329 0,10480019 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05819329 0,1047218 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05819329 0,10464353 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,05819329 0,10456538 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05819329 0,10448735 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05819329 0,10440943 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,05819329 0,10433163 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05819329 0,10425395 ! response to dsRNA GO:0043331 20 10 0,000 0,05819329 0,10417638 ! DNA ligation GO:0006266 19 10 0,000 0,05819329 0,10409892 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05819329 0,10402158 ! melanosome localization GO:0032400 16 10 0,000 0,05819329 0,10394436 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05819329 0,10386725 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05819329 0,10379025 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05819329 0,10371337 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05819329 0,1036366 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05819329 0,10355995 ! mRNA cleavage GO:0006379 17 10 0,000 0,05819329 0,10348341 ! protein sumoylation GO:0016925 15 10 0,000 0,05819329 0,10340698 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05819329 0,10333066 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05819329 0,10325446 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05819329 0,10317837 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05819329 0,10310239 ! salivary gland development GO:0007431 27 10 0,000 0,05819329 0,10302653 ! prophase GO:0051324 15 10 0,000 0,05819329 0,10295077 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05819329 0,10287513 ! apical protein localization GO:0045176 15 10 0,000 0,05819329 0,1027996 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05819329 0,10272417 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05819329 0,10264886 ! midbrain development GO:0030901 13 10 0,000 0,05819329 0,10257366 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05819329 0,10249857 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05819329 0,10242359 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05819329 0,10234872 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05819329 0,10227396 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05819329 0,10219931 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05819329 0,10212476 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05819329 0,10205033 ! detection of calcium ion GO:0005513 23 10 0,000 0,05819329 0,101976 ! oocyte development GO:0048599 17 10 0,000 0,05819329 0,10190178 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05819329 0,10182767 ! blastocyst formation GO:0001825 17 10 0,000 0,05819329 0,10175367 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05819329 0,10167977 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05819329 0,10160599 ! activation of innate immune response GO:0002218 12 10 0,000 0,05819329 0,10153231 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05819329 0,10145873 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05819329 0,10138526 ! response to nicotine GO:0035094 20 10 0,000 0,05819329 0,1013119 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05819329 0,10123865 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05819329 0,1011655 ! localization within membrane GO:0051668 20 10 0,000 0,05819329 0,10109245 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,05941024 0,10313206 ! developmental maturation GO:0021700 116 66 1,000 0,05941024 0,1030577 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,0610044 0,10574683 ! adaptive immune response GO:0002250 119 67 1,000 0,0610044 0,1056707 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 1,000 0,0610044 0,10559467 ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,06261314 0,10830137 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 1,000 0,06261314 0,10822357 ! respiratory burst GO:0045730 17 11 0,000 0,06382404 0,11023737 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06382404 0,11015829 ! neuron fate specification GO:0048665 17 11 0,000 0,06382404 0,11007932 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06382404 0,11000047 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06382404 0,10992173 ! thyroid gland development GO:0030878 26 11 0,000 0,06382404 0,1098431 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06382404 0,10976458 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06382404 0,10968618 ! response to pain GO:0048265 24 11 0,000 0,06382404 0,10960789 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,06382404 0,10952971 ! T cell proliferation GO:0042098 26 11 0,000 0,06382404 0,10945164 ! bone resorption GO:0045453 16 11 0,000 0,06382404 0,10937368 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06382404 0,10929584 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06382404 0,1092181 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06382404 0,10914048 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06382404 0,10906296 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06382404 0,10898556 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06382404 0,10890826 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06382404 0,10883108 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06382404 0,108754 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06382404 0,10867704 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,06382404 0,10860018 ! lipid digestion GO:0044241 18 11 0,000 0,06382404 0,10852343 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06382404 0,10844679 ! UV protection GO:0009650 19 11 0,000 0,06382404 0,10837026 ! adult heart development GO:0007512 14 11 0,000 0,06382404 0,10829383 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,06382404 0,10821751 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06382404 0,1081413 ! temperature homeostasis GO:0001659 17 11 0,000 0,06382404 0,1080652 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06382404 0,10798921 ! negative regulation of ossification GO:0030279 26 11 0,000 0,06382404 0,10791332 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06382404 0,10783754 ! regulation of organ growth GO:0046620 13 11 0,000 0,06382404 0,10776186 ! pigment granule localization GO:0051875 20 11 0,000 0,06382404 0,10768629 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06382404 0,10761083 ! vasoconstriction GO:0042310 18 11 0,000 0,06382404 0,10753547 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06382404 0,10746022 ! embryonic axis specification GO:0000578 18 11 0,000 0,06382404 0,10738507 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06382404 0,10731003 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06382404 0,10723509 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06382404 0,10716026 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06382404 0,10708553 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06382404 0,10701091 ! zymogen activation GO:0031638 15 11 0,000 0,06382404 0,10693639 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06382404 0,10686197 ! neuroblast proliferation GO:0007405 24 11 0,000 0,06382404 0,10678766 ! nucleosome positioning GO:0016584 15 11 0,000 0,06382404 0,10671345 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06382404 0,10663934 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06382404 0,10656534 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06382404 0,10649144 ! acid secretion GO:0046717 18 11 0,000 0,06382404 0,10641764 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06382404 0,10634394 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06382404 0,10627035 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06382404 0,10619685 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06382404 0,10612346 ! oocyte differentiation GO:0009994 18 11 0,000 0,06382404 0,10605017 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06382404 0,10597699 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,06382404 0,1059039 ! cholesterol efflux GO:0033344 19 11 0,000 0,06382404 0,10583091 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06382404 0,10575802 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06382404 0,10568524 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,06382404 0,10561255 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,06382404 0,10553997 ! embryonic gut development GO:0048566 15 11 0,000 0,06382404 0,10546748 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06382404 0,10539509 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06382404 0,10532281 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06382404 0,10525062 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06382404 0,10517853 ! defense response to fungus GO:0050832 13 11 0,000 0,06382404 0,10510654 ! developmental induction GO:0031128 19 11 0,000 0,06382404 0,10503465 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,06382404 0,10496285 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06382404 0,10489116 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06382404 0,10481956 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06382404 0,10474806 ! regulation of embryonic development GO:0045995 27 11 0,000 0,06382404 0,10467665 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06382404 0,10460535 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,06423621 0,10520921 ! coenzyme biosynthetic process GO:0009108 102 69 1,000 0,06423621 0,10513763 ! regulation of caspase activity GO:0043281 122 72 1,000 0,06918921 0,11316739 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,06918921 0,11309051 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,06918921 0,11301374 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06942132 0,11331595 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06942132 0,11323912 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06942132 0,1131624 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06942132 0,11308578 ! virus-host interaction GO:0019048 29 12 0,000 0,06942132 0,11300927 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06942132 0,11293286 ! cartilage condensation GO:0001502 20 12 0,000 0,06942132 0,11285656 ! mating GO:0007618 17 12 0,000 0,06942132 0,11278035 ! protein complex disassembly GO:0043241 27 12 0,000 0,06942132 0,11270425 GO:0043624|cellular protein complex disassembly, ! hippocampus development GO:0021766 26 12 0,000 0,06942132 0,11262826 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06942132 0,11255236 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06942132 0,11247657 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,06942132 0,11240088 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06942132 0,11232529 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06942132 0,1122498 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06942132 0,11217442 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06942132 0,11209913 ! drug transport GO:0015893 16 12 0,000 0,06942132 0,11202395 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06942132 0,11194886 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06942132 0,11187388 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06942132 0,111799 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06942132 0,11172422 ! focal adhesion formation GO:0048041 35 12 0,000 0,06942132 0,11164953 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06942132 0,11157495 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06942132 0,11150047 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06942132 0,11142609 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06942132 0,1113518 ! fear response GO:0042596 26 12 0,000 0,06942132 0,11127762 ! monoamine transport GO:0015844 18 12 0,000 0,06942132 0,11120353 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06942132 0,11112954 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06942132 0,11105565 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06942132 0,11098186 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06942132 0,11090817 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06942132 0,11083457 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06942132 0,11076108 ! protein homotetramerization GO:0051289 21 12 0,000 0,06942132 0,11068768 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06942132 0,11061437 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06942132 0,11054117 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06942132 0,11046806 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06942132 0,11039505 ! cranial nerve development GO:0021545 20 12 0,000 0,06942132 0,11032213 ! fucose catabolic process GO:0019317 22 12 0,000 0,06942132 0,11024931 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06942132 0,11017659 ! histone methylation GO:0016571 26 12 0,000 0,06942132 0,11010396 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06942132 0,11003143 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06942132 0,10995899 ! gland morphogenesis GO:0022612 29 12 0,000 0,06942132 0,10988665 ! T cell homeostasis GO:0043029 25 12 0,000 0,06942132 0,1098144 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06942132 0,10974225 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06942132 0,10967019 ! spleen development GO:0048536 22 12 0,000 0,06942132 0,10959823 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,06942132 0,10952636 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06942132 0,10945459 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06942132 0,10938291 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06942132 0,10931132 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06942132 0,10923983 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06942132 0,10916843 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06942132 0,10909713 ! lipoprotein metabolic process GO:0042157 131 73 1,000 0,07086739 0,11129696 ! fertilization GO:0009566 90 73 1,000 0,07086739 0,11122436 ! neurotransmitter transport GO:0006836 123 74 1,000 0,07255881 0,11380475 ! exocytosis GO:0006887 133 74 1,000 0,07255881 0,11373061 ! regulation of actin cytoskeleton organization GO:0032956 149 74 1,000 0,07255881 0,11365657 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,07255881 0,11358262 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,07426323 0,11617512 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07498532 0,11722851 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07498532 0,11715239 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07498532 0,11707637 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,07498532 0,11700044 ! lipid localization GO:0010876 28 13 0,000 0,07498532 0,11692462 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,07498532 0,11684889 ! organelle fusion GO:0048284 32 13 0,000 0,07498532 0,11677326 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07498532 0,11669773 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07498532 0,11662229 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07498532 0,11654695 ! endocrine pancreas development GO:0031018 22 13 0,000 0,07498532 0,11647171 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07498532 0,11639657 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07498532 0,11632152 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07498532 0,11624657 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07498532 0,11617172 ! methionine metabolic process GO:0006555 27 13 0,000 0,07498532 0,11609696 ! plasma membrane organization GO:0007009 24 13 0,000 0,07498532 0,1160223 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07498532 0,11594774 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07498532 0,11587327 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,07498532 0,1157989 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,07498532 0,11572462 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,07498532 0,11565044 ! response to X-ray GO:0010165 25 13 0,000 0,07498532 0,11557635 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07498532 0,11550236 ! exocrine system development GO:0035272 32 13 0,000 0,07498532 0,11542846 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,07498532 0,11535466 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07498532 0,11528095 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07498532 0,11520733 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07498532 0,11513381 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07498532 0,11506038 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07498532 0,11498705 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07498532 0,11491381 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,07498532 0,11484066 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07498532 0,11476761 ! regulation of cellular pH GO:0030641 22 13 0,000 0,07498532 0,11469465 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07498532 0,11462178 ! ribosome assembly GO:0042255 17 13 0,000 0,07498532 0,11454901 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07498532 0,11447632 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07498532 0,11440373 ! chromatin silencing GO:0006342 26 13 0,000 0,07498532 0,11433123 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07498532 0,11425882 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07498532 0,11418651 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07498532 0,11411428 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07498532 0,11404215 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07498532 0,11397011 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07498532 0,11389816 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07498532 0,1138263 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,07498532 0,11375453 ! insulin secretion GO:0030073 23 13 0,000 0,07498532 0,11368285 ! actin filament polymerization GO:0030041 24 13 0,000 0,07498532 0,11361126 ! acrosome reaction GO:0007340 18 13 0,000 0,07498532 0,11353976 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,07598045 0,11497419 ! regulation of actin filament-based process GO:0032970 152 77 1,000 0,07771026 0,11751784 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,07771026 0,11744402 ! blood coagulation GO:0007596 146 78 1,000 0,07945244 0,12000161 GO:0050817|coagulation, ! protein oligomerization GO:0051259 139 78 1,000 0,07945244 0,11992633 ! lactation GO:0007595 26 14 0,000 0,08051624 0,12145584 ! reproductive cellular process GO:0048610 20 14 0,000 0,08051624 0,12137974 ! water transport GO:0006833 21 14 0,000 0,08051624 0,12130373 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,08051624 0,12122782 ! non-recombinational repair GO:0000726 25 14 0,000 0,08051624 0,12115201 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,08051624 0,12107629 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,08051624 0,12100066 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,08051624 0,12092513 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,08051624 0,1208497 ! RNA polyadenylation GO:0043631 30 14 0,000 0,08051624 0,12077435 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,08051624 0,1206991 ! palate development GO:0060021 31 14 0,000 0,08051624 0,12062395 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,08051624 0,12054889 ! regulated secretory pathway GO:0045055 23 14 0,000 0,08051624 0,12047392 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,08051624 0,12039904 ! arginine metabolic process GO:0006525 17 14 0,000 0,08051624 0,12032426 ! regulation of heart rate GO:0002027 24 14 0,000 0,08051624 0,12024957 ! organic alcohol transport GO:0015850 29 14 0,000 0,08051624 0,12017498 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,08051624 0,12010047 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,08051624 0,12002606 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,08051624 0,11995174 ! neutral amino acid transport GO:0015804 26 14 0,000 0,08051624 0,11987751 ! L-amino acid transport GO:0015807 30 14 0,000 0,08051624 0,11980338 ! bone mineralization GO:0030282 17 14 0,000 0,08051624 0,11972933 ! stem cell development GO:0048864 43 14 0,000 0,08051624 0,11965538 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,08051624 0,11958152 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,08051624 0,11950775 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,08051624 0,11943407 ! cerebellum development GO:0021549 21 14 0,000 0,08051624 0,11936048 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,08051624 0,11928698 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,08051624 0,11921358 ! response to gamma radiation GO:0010332 28 14 0,000 0,08051624 0,11914026 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,08051624 0,11906703 ! cofactor transport GO:0051181 26 14 0,000 0,08051624 0,1189939 ! NADP metabolic process GO:0006739 24 14 0,000 0,08051624 0,11892085 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,08051624 0,11884789 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,08051624 0,11877502 ! oxygen transport GO:0015671 21 14 0,000 0,08051624 0,11870224 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08051624 0,11862955 ! male genitalia development GO:0030539 24 14 0,000 0,08051624 0,11855695 ! regulation of axon extension GO:0030516 37 14 0,000 0,08051624 0,11848444 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,08051624 0,11841202 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,08051624 0,11833968 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,08120679 0,11928177 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,08120679 0,11920899 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,08120679 0,1191363 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,0829731 0,12165343 ! muscle cell differentiation GO:0042692 159 80 1,000 0,0829731 0,12157934 ! T cell activation GO:0042110 168 81 1,000 0,08475117 0,12410914 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,08475117 0,12403365 GO:0045937|positive regulation of phosphate metabolic process, ! digestion GO:0007586 112 81 1,000 0,08475117 0,12395825 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,08475117 0,12388294 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,08475117 0,12380773 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,08601426 0,12557665 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08601426 0,12550049 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,08601426 0,12542443 ! superoxide anion generation GO:0042554 20 15 0,000 0,08601426 0,12534846 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,08601426 0,12527259 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,08601426 0,1251968 ! copper ion transport GO:0006825 20 15 0,000 0,08601426 0,12512111 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,08601426 0,12504551 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,08601426 0,12497 ! sulfate transport GO:0008272 23 15 0,000 0,08601426 0,12489458 ! response to cAMP GO:0051591 22 15 0,000 0,08601426 0,12481925 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,08601426 0,12474401 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,08601426 0,12466886 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,08601426 0,12459381 ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,08601426 0,12451884 ! response to hexose stimulus GO:0009746 22 15 0,000 0,08601426 0,12444396 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! vesicle coating GO:0006901 33 15 0,000 0,08601426 0,12436918 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,08601426 0,12429448 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,08601426 0,12421988 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,08601426 0,12414536 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,08601426 0,12407093 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,08601426 0,12399659 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,08601426 0,12392234 ! regulation of vasodilation GO:0042312 26 15 0,000 0,08601426 0,12384818 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,08601426 0,12377411 ! histone deacetylation GO:0016575 20 15 0,000 0,08601426 0,12370013 ! mRNA splice site selection GO:0006376 38 15 0,000 0,08601426 0,12362623 ! tissue regeneration GO:0042246 26 15 0,000 0,08601426 0,12355243 ! water homeostasis GO:0030104 27 15 0,000 0,08601426 0,12347871 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08601426 0,12340508 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,08601426 0,12333153 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,08601426 0,12325808 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08601426 0,12318471 ! heme biosynthetic process GO:0006783 29 15 0,000 0,08601426 0,12311143 ! cell killing GO:0001906 29 15 0,000 0,08601426 0,12303824 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,08601426 0,12296513 ! detection of bacterium GO:0016045 18 15 0,000 0,08601426 0,12289211 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,08601426 0,12281918 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,08601426 0,12274633 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,08601426 0,12267357 ! peptide hormone processing GO:0016486 23 15 0,000 0,08601426 0,1226009 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,0865408 0,12327837 ! response to drug GO:0042493 143 82 1,000 0,0865408 0,12320543 ! response to nutrient GO:0007584 125 82 1,000 0,0865408 0,12313257 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,0865408 0,12305979 ! regulation of lyase activity GO:0051339 160 83 1,000 0,08834179 0,12554657 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,09015393 0,12804626 ! hemostasis GO:0007599 158 84 1,000 0,09015393 0,12797072 ! negative regulation of transport GO:0051051 153 84 1,000 0,09015393 0,12789526 ! regulation of ligase activity GO:0051340 142 84 1,000 0,09015393 0,1278199 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,09147959 0,12962303 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,09147959 0,12954674 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,09147959 0,12947053 ! bone remodeling GO:0046849 27 16 0,000 0,09147959 0,12939442 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,09147959 0,12931839 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,09147959 0,12924246 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,09147959 0,12916661 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,09147959 0,12909085 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,09147959 0,12901518 ! startle response GO:0001964 28 16 0,000 0,09147959 0,1289396 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,09147959 0,12886411 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,09147959 0,12878871 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,09147959 0,12871339 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,09147959 0,12863817 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,09147959 0,12856303 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,09147959 0,12848798 ! protein polyubiquitination GO:0000209 34 16 0,000 0,09147959 0,12841301 ! glutamate metabolic process GO:0006536 22 16 0,000 0,09147959 0,12833814 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,09147959 0,12826335 ! response to osmotic stress GO:0006970 25 16 0,000 0,09147959 0,12818864 ! lysosomal transport GO:0007041 26 16 0,000 0,09147959 0,12811403 ! fructose metabolic process GO:0006000 25 16 0,000 0,09147959 0,1280395 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,09147959 0,12796506 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,09147959 0,1278907 ! intermediate filament-based process GO:0045103 32 16 0,000 0,09147959 0,12781644 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,09147959 0,12774225 ! negative regulation of immune response GO:0050777 35 16 0,000 0,09147959 0,12766816 ! axon cargo transport GO:0008088 43 16 0,000 0,09147959 0,12759415 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,09147959 0,12752022 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,09147959 0,12744638 ! DNA replication initiation GO:0006270 27 16 0,000 0,09147959 0,12737263 ! neuron recognition GO:0008038 35 16 0,000 0,09147959 0,12729896 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,09147959 0,12722538 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,09147959 0,12715188 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,09147959 0,12707847 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,09147959 0,12700514 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,09147959 0,12693189 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,09147959 0,12685873 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,09147959 0,12678566 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09147959 0,12671267 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,09147959 0,12663976 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,09147959 0,12656694 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,09147959 0,1264942 ! defense response to virus GO:0051607 37 16 0,000 0,09147959 0,12642154 ! response to unfolded protein GO:0006986 131 85 1,000 0,09197704 0,12703603 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,09197704 0,12696315 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,09197704 0,12689035 GO:0002696|positive regulation of leukocyte activation, ! oxidative phosphorylation GO:0006119 133 86 1,000 0,09381092 0,12934617 ! mitochondrion organization GO:0007005 148 86 1,000 0,09381092 0,12927209 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,09565537 0,13173831 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of protein transport GO:0051223 154 87 1,000 0,09565537 0,13166295 GO:0070201|regulation of establishment of protein localization, ! positive regulation of cell killing GO:0031343 32 17 0,000 0,09691243 0,13331692 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,09691243 0,13324074 ! metencephalon development GO:0022037 30 17 0,000 0,09691243 0,13316465 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,09691243 0,13308864 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,09691243 0,13301272 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,09691243 0,13293689 ! endothelial cell migration GO:0043542 28 17 0,000 0,09691243 0,13286114 ! inositol metabolic process GO:0006020 28 17 0,000 0,09691243 0,13278548 ! gene silencing by RNA GO:0031047 36 17 0,000 0,09691243 0,1327099 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,09691243 0,13263441 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,09691243 0,13255901 ! adult walking behavior GO:0007628 33 17 0,000 0,09691243 0,13248369 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,09691243 0,13240846 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,09691243 0,13233331 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,09691243 0,13225825 ! myoblast differentiation GO:0045445 45 17 0,000 0,09691243 0,13218327 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,09691243 0,13210838 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,09691243 0,13203358 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,09691243 0,13195886 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,09691243 0,13188422 ! glycine metabolic process GO:0006544 28 17 0,000 0,09691243 0,13180966 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 0,000 0,09691243 0,1317352 ! NAD metabolic process GO:0019674 29 17 0,000 0,09691243 0,13166081 ! membrane budding GO:0006900 37 17 0,000 0,09691243 0,13158651 ! DNA integration GO:0015074 29 17 0,000 0,09691243 0,13151229 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,09691243 0,13143816 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,09691243 0,13136411 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,09691243 0,13129014 ! genitalia development GO:0048806 30 17 0,000 0,09691243 0,13121626 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,09691243 0,13114246 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,09691243 0,13106874 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,09691243 0,13099511 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,09691243 0,13092156 ! steroid catabolic process GO:0006706 31 17 0,000 0,09691243 0,13084809 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,09691243 0,1307747 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,09691243 0,1307014 ! gas transport GO:0015669 25 17 0,000 0,09691243 0,13062818 ! organic cation transport GO:0015695 31 17 0,000 0,09691243 0,13055504 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,09691243 0,13048198 ! cellular respiration GO:0045333 135 88 1,000 0,09751022 0,13121341 ! positive regulation of protein modification process GO:0031401 136 88 1,000 0,09751022 0,13114007 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,10125031 0,136094 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,10231295 0,13744554 ! neuron maturation GO:0042551 42 18 0,000 0,10231295 0,13736884 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,10231295 0,13729222 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,10231295 0,13721569 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,10231295 0,13713925 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,10231295 0,13706289 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,10231295 0,13698662 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,10231295 0,13691043 ! patterning of blood vessels GO:0001569 39 18 0,000 0,10231295 0,13683433 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,10231295 0,13675831 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,10231295 0,13668237 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,10231295 0,13660652 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,10231295 0,13653076 ! glutamine metabolic process GO:0006541 29 18 0,000 0,10231295 0,13645508 ! response to retinoic acid GO:0032526 26 18 0,000 0,10231295 0,13637948 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,10231295 0,13630396 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,10231295 0,13622853 ! response to fungus GO:0009620 21 18 0,000 0,10231295 0,13615318 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,10231295 0,13607792 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,10231295 0,13600274 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,10231295 0,13592764 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,10231295 0,13585263 ! vitamin transport GO:0051180 27 18 0,000 0,10231295 0,13577769 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,10231295 0,13570284 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,10231295 0,13562808 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,10231295 0,13555339 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,10231295 0,13547879 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,10231295 0,13540427 ! nerve development GO:0021675 28 18 0,000 0,10231295 0,13532983 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,10231295 0,13525547 ! response to protein stimulus GO:0051789 149 91 1,000 0,10313519 0,13626759 ! cofactor biosynthetic process GO:0051188 139 91 1,000 0,10313519 0,1361928 ! regulation of defense response GO:0031347 149 92 1,000 0,10502972 0,13861849 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,10693371 0,14105401 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,10693371 0,14097672 ! regulation of membrane potential GO:0042391 164 93 1,000 0,10693371 0,14089951 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,10693371 0,14082239 ! protein secretion GO:0009306 39 19 0,000 0,10768136 0,1417294 ! positive regulation of translation GO:0045727 30 19 0,000 0,10768136 0,14165191 ! negative regulation of defense response GO:0031348 25 19 0,000 0,10768136 0,1415745 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,10768136 0,14149718 ! skin development GO:0043588 36 19 0,000 0,10768136 0,14141995 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,10768136 0,14134279 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,10768136 0,14126573 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,10768136 0,14118874 ! bile acid metabolic process GO:0008206 29 19 0,000 0,10768136 0,14111184 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,10768136 0,14103503 ! response to vitamin A GO:0033189 27 19 0,000 0,10768136 0,14095829 ! heme metabolic process GO:0042168 36 19 0,000 0,10768136 0,14088164 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,10768136 0,14080508 ! plasma membrane fusion GO:0045026 28 19 0,000 0,10768136 0,14072859 ! protein export from nucleus GO:0006611 36 19 0,000 0,10768136 0,14065219 ! heart process GO:0003015 30 19 0,000 0,10768136 0,14057588 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,10768136 0,14049964 ! visual learning GO:0008542 36 19 0,000 0,10768136 0,14042349 ! cellular pigmentation GO:0033059 36 19 0,000 0,10768136 0,14034742 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,10768136 0,14027144 ! cell-cell junction organization GO:0045216 35 19 0,000 0,10768136 0,14019553 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,10768136 0,14011971 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,10768136 0,14004397 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,10768136 0,13996831 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,10768136 0,13989273 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,10768136 0,13981724 ! cilium assembly GO:0042384 37 19 0,000 0,10768136 0,13974182 ! peptide hormone secretion GO:0030072 31 19 0,000 0,10768136 0,13966649 ! regulation of T cell activation GO:0050863 158 94 1,000 0,10884699 0,14110229 ! forebrain development GO:0030900 188 95 1,000 0,11076937 0,14351702 ! positive regulation of immune response GO:0050778 156 96 1,000 0,11270068 0,14594071 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,11301784 0,14627268 ! positive regulation of ossification GO:0045778 47 20 0,000 0,11301784 0,14619404 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,11301784 0,14611548 ! cAMP metabolic process GO:0046058 36 20 0,000 0,11301784 0,14603701 ! response to vitamin GO:0033273 31 20 0,000 0,11301784 0,14595862 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,11301784 0,14588032 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,11301784 0,1458021 ! response to alkaloid GO:0043279 38 20 0,000 0,11301784 0,14572396 ! retinoid metabolic process GO:0001523 32 20 0,000 0,11301784 0,14564591 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,11301784 0,14556794 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,11301784 0,14549005 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,11301784 0,14541225 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,11301784 0,14533453 GO:0032392|DNA geometric change, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 0,000 0,11301784 0,1452569 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,11301784 0,14517934 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,11301784 0,14510187 ! body fluid secretion GO:0007589 31 20 0,000 0,11301784 0,14502449 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,11301784 0,14494718 ! peptide secretion GO:0002790 35 20 0,000 0,11301784 0,14486996 ! stem cell differentiation GO:0048863 53 20 0,000 0,11301784 0,14479282 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,11301784 0,14471576 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,11301784 0,14463878 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,11301784 0,14456189 ! sensory perception of pain GO:0019233 30 20 0,000 0,11301784 0,14448508 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,11301784 0,14440834 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,11301784 0,14433169 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,11301784 0,14425513 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,11301784 0,14417864 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,11301784 0,14410223 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,11301784 0,14402591 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,11301784 0,14394966 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,11301784 0,1438735 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,11301784 0,14379742 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,11301784 0,14372141 ! regulation of glucose import GO:0046324 29 20 0,000 0,11301784 0,14364549 GO:0010827|regulation of glucose transport, ! actin filament-based movement GO:0030048 43 20 0,000 0,11301784 0,14356965 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,11301784 0,14349389 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,11301784 0,1434182 ! negative regulation of translation GO:0017148 29 20 0,000 0,11301784 0,1433426 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,11301784 0,14326708 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,11301784 0,14319163 ! regulation of protein localization GO:0032880 176 97 1,000 0,11464076 0,1451714 ! regulation of cell killing GO:0031341 42 21 0,000 0,11832258 0,14975493 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,11832258 0,14967619 ! hormone secretion GO:0046879 38 21 0,000 0,11832258 0,14959754 ! glycerol metabolic process GO:0006071 34 21 0,000 0,11832258 0,14951897 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,11832258 0,14944048 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,11832258 0,14936208 ! axis specification GO:0009798 38 21 0,000 0,11832258 0,14928375 ! ovarian follicle development GO:0001541 35 21 0,000 0,11832258 0,14920551 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,11832258 0,14912735 ! smooth muscle contraction GO:0006939 46 21 0,000 0,11832258 0,14904928 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,11832258 0,14897128 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,11832258 0,14889337 ! cell aging GO:0007569 44 21 0,000 0,11832258 0,14881554 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,11832258 0,14873778 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,11832258 0,14866011 ! cytolysis GO:0019835 24 21 0,000 0,11832258 0,14858253 ! vasodilation GO:0042311 39 21 0,000 0,11832258 0,14850502 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,11832258 0,14842759 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,11832258 0,14835024 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,11832258 0,14827298 ! oogenesis GO:0048477 36 21 0,000 0,11832258 0,14819579 ! collagen fibril organization GO:0030199 59 21 0,000 0,11832258 0,14811869 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,11832258 0,14804166 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,11832258 0,14796472 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,11832258 0,14788785 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,11832258 0,14781107 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,11832258 0,14773436 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,11832258 0,14765774 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,11832258 0,14758119 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,11832258 0,14750472 ! collagen catabolic process GO:0030574 28 21 0,000 0,11832258 0,14742834 ! sperm-egg recognition GO:0035036 21 21 0,000 0,11832258 0,14735203 ! gut development GO:0048565 39 21 0,000 0,11832258 0,1472758 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,11854649 0,14747821 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,12359577 0,15368032 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,12359577 0,15360094 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,12359577 0,15352164 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,12359577 0,15344242 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,12359577 0,15336329 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,12359577 0,15328423 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,12359577 0,15320526 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,12359577 0,15312637 ! regeneration GO:0031099 41 22 0,000 0,12359577 0,15304756 ! keratinization GO:0031424 28 22 0,000 0,12359577 0,15296883 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,12359577 0,15289019 ! sensory perception of taste GO:0050909 28 22 0,000 0,12359577 0,15281162 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,12359577 0,15273314 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,12359577 0,15265473 ! vacuolar transport GO:0007034 36 22 0,000 0,12359577 0,15257641 ! lysosome organization GO:0007040 41 22 0,000 0,12359577 0,15249816 ! central nervous system neuron development GO:0021954 46 22 0,000 0,12359577 0,15242 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,12359577 0,15234191 ! fucose metabolic process GO:0006004 39 22 0,000 0,12359577 0,15226391 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,12359577 0,15218599 ! ureteric bud development GO:0001657 43 22 0,000 0,12359577 0,15210814 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,12359577 0,15203038 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,12359577 0,15195269 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,12359577 0,15187508 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,12359577 0,15179756 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,12359577 0,15172011 ! sarcomere organization GO:0045214 30 22 0,000 0,12359577 0,15164274 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,12359577 0,15156545 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,12359577 0,15148824 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,12359577 0,15141111 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,12883759 0,15775229 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,12883759 0,15767205 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,12883759 0,15759189 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,12883759 0,15751181 ! gluconeogenesis GO:0006094 33 23 0,000 0,12883759 0,15743182 ! viral genome replication GO:0019079 41 23 0,000 0,12883759 0,1573519 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,12883759 0,15727207 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,12883759 0,15719232 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,12883759 0,15711265 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,12883759 0,15703305 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,12883759 0,15695354 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,12883759 0,15687411 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,12883759 0,15679476 ! response to ethanol GO:0045471 46 23 0,000 0,12883759 0,1567155 ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,12883759 0,15663631 ! peroxisome organization GO:0007031 37 23 0,000 0,12883759 0,1565572 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,12883759 0,15647817 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,12883759 0,15639922 GO:0042278|purine nucleoside metabolic process, ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,12883759 0,15632035 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,12883759 0,15624156 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,12883759 0,15616285 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,12883759 0,15608421 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,12883759 0,15600566 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,12883759 0,15592719 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,12883759 0,15584879 ! fatty acid transport GO:0015908 44 23 0,000 0,12883759 0,15577048 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,12883759 0,15569224 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,12883759 0,15561408 ! hormone transport GO:0009914 40 23 0,000 0,12883759 0,155536 ! cell-cell recognition GO:0009988 25 23 0,000 0,12883759 0,155458 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,12883759 0,15538007 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,12883759 0,15530223 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,12883759 0,15522446 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,13404824 0,16142146 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,13404824 0,1613407 GO:0016444|somatic cell DNA recombination, ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,13404824 0,16126003 ! vesicle docking GO:0048278 47 24 0,000 0,13404824 0,16117944 ! spinal cord development GO:0021510 47 24 0,000 0,13404824 0,16109893 ! vacuole organization GO:0007033 43 24 0,000 0,13404824 0,16101851 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,13404824 0,16093816 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,13404824 0,16085789 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,13404824 0,1607777 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,13404824 0,16069759 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,13404824 0,16061756 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,13404824 0,16053761 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,13404824 0,16045775 ! membrane depolarization GO:0051899 39 24 0,000 0,13404824 0,16037796 ! pentose metabolic process GO:0019321 35 24 0,000 0,13404824 0,16029824 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,13404824 0,16021861 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,13404824 0,16013906 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,13404824 0,16005959 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,13404824 0,15998019 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,13404824 0,15990088 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,13404824 0,15982164 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,13404824 0,15974248 ! regulation of amine transport GO:0051952 40 24 0,000 0,13404824 0,1596634 ! protein tetramerization GO:0051262 52 24 0,000 0,13404824 0,1595844 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,13922789 0,1656688 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,13922789 0,16558691 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,13922789 0,1655051 ! phototransduction GO:0007602 33 25 0,000 0,13922789 0,16542337 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,13922789 0,16534171 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,13922789 0,16526015 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,13922789 0,16517866 ! chromosome condensation GO:0030261 45 25 0,000 0,13922789 0,16509725 ! osteoblast differentiation GO:0001649 60 25 0,000 0,13922789 0,16501592 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,13922789 0,16493467 ! negative regulation of cell development GO:0010721 73 25 0,000 0,13922789 0,1648535 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,13922789 0,16477241 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,13922789 0,1646914 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,13922789 0,16461047 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,13922789 0,16452962 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,13922789 0,16444885 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,13922789 0,16436816 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,13922789 0,16428755 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,13922789 0,16420702 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,13922789 0,16412656 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,13922789 0,16404619 ! telomere organization GO:0032200 43 25 0,000 0,13922789 0,16396589 GO:0000723|telomere maintenance, ! liver development GO:0001889 53 25 0,000 0,13922789 0,16388567 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,14437674 0,16986329 ! embryonic pattern specification GO:0009880 44 26 0,000 0,14437674 0,16978027 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,14437674 0,16969733 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,14437674 0,16961447 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,14437674 0,16953169 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,14437674 0,16944899 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,14437674 0,16936637 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,14437674 0,16928384 ! molting cycle process GO:0022404 50 26 0,000 0,14437674 0,16920138 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,14437674 0,169119 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,14437674 0,16903671 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,14437674 0,16895449 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,14437674 0,16887235 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,14437674 0,1687903 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,14437674 0,16870832 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,14437674 0,16862642 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,14437674 0,1685446 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,14437674 0,16846287 ! blastocyst development GO:0001824 49 26 0,000 0,14437674 0,16838121 ! leukocyte proliferation GO:0070661 52 26 0,000 0,14437674 0,16829963 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,14437674 0,16821813 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,14437674 0,1681367 ! neuron fate commitment GO:0048663 48 27 0,000 0,14949495 0,17401299 ! iron ion transport GO:0006826 59 27 0,000 0,14949495 0,17392885 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,14949495 0,17384478 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,14949495 0,1737608 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,14949495 0,1736769 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,14949495 0,17359308 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,14949495 0,17350934 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,14949495 0,17342568 ! autophagy GO:0006914 41 27 0,000 0,14949495 0,1733421 ! response to toxin GO:0009636 47 27 0,000 0,14949495 0,1732586 ! base-excision repair GO:0006284 41 27 0,000 0,14949495 0,17317518 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,14949495 0,17309184 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,14949495 0,17300859 ! glutathione metabolic process GO:0006749 39 27 0,000 0,14949495 0,17292541 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,14949495 0,17284231 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,14949495 0,1727593 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,14949495 0,17267636 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,15458272 0,17846738 ! circadian rhythm GO:0007623 50 28 0,000 0,15458272 0,17838178 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,15458272 0,17829627 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,15458272 0,17821084 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,15458272 0,17812549 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,15458272 0,17804022 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,15458272 0,17795503 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,15458272 0,17786993 ! synaptogenesis GO:0007416 42 28 0,000 0,15458272 0,1777849 ! lipid oxidation GO:0034440 43 28 0,000 0,15458272 0,17769996 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,15458272 0,1776151 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,15458272 0,17753032 ! translational initiation GO:0006413 65 29 0,000 0,15964022 0,18325113 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,15964022 0,18316374 ! regulation of pH GO:0006885 43 29 0,000 0,15964022 0,18307644 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,15964022 0,18298922 ! catechol metabolic process GO:0009712 54 29 0,000 0,15964022 0,18290208 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,15964022 0,18281502 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,15964022 0,18272805 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,15964022 0,18264116 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,15964022 0,18255436 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,15964022 0,18246763 ! cell fate determination GO:0001709 60 29 0,000 0,15964022 0,18238099 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,15964022 0,18229443 ! detection of light stimulus GO:0009583 38 29 0,000 0,15964022 0,18220795 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,15964022 0,18212156 ! tissue homeostasis GO:0001894 48 29 0,000 0,15964022 0,18203524 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,15964022 0,18194901 ! phenol metabolic process GO:0018958 55 30 0,000 0,16466763 0,18759011 ! zinc ion transport GO:0006829 45 30 0,000 0,16466763 0,18750133 ! membrane docking GO:0022406 61 30 0,000 0,16466763 0,18741264 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,16466763 0,18732403 ! cell junction assembly GO:0034329 78 30 0,000 0,16466763 0,1872355 ! regulation of innate immune response GO:0045088 51 30 0,000 0,16466763 0,18714706 ! acute-phase response GO:0006953 49 30 0,000 0,16466763 0,1870587 ! myofibril assembly GO:0030239 47 30 0,000 0,16466763 0,18697042 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,16466763 0,18688223 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,16466763 0,18679412 ! phospholipid transport GO:0015914 51 30 0,000 0,16466763 0,18670609 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,16466763 0,18661814 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,16466763 0,18653028 ! eye morphogenesis GO:0048592 60 30 0,000 0,16466763 0,1864425 ! response to heat GO:0009408 50 30 0,000 0,16466763 0,18635481 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,16966513 0,19192022 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,16966513 0,19183003 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,16966513 0,19173993 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,16966513 0,19164991 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,16966513 0,19155997 ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,16966513 0,19147013 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,16966513 0,19138036 ! ovulation cycle process GO:0022602 49 31 0,000 0,16966513 0,19129068 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,16966513 0,19120108 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,16966513 0,19111157 ! peptide transport GO:0015833 55 31 0,000 0,16966513 0,19102214 ! mesoderm formation GO:0001707 69 31 0,000 0,16966513 0,19093279 ! natural killer cell activation GO:0030101 45 31 0,000 0,16966513 0,19084353 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,16966513 0,19075435 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,16966513 0,19066525 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,1746329 0,19615628 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,1746329 0,19606475 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,1746329 0,1959733 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,1746329 0,19588194 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,1746329 0,19579066 ! spliceosome assembly GO:0000245 67 32 0,000 0,1746329 0,19569947 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,1746329 0,19560836 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,1746329 0,19551734 ! response to ionizing radiation GO:0010212 65 32 0,000 0,1746329 0,1954264 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,1746329 0,19533554 ! muscle cell development GO:0055001 49 32 0,000 0,1746329 0,19524478 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,1746329 0,19515409 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,1746329 0,19506349 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,1746329 0,19497297 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,1746329 0,19488254 ! ovulation cycle GO:0042698 51 32 0,000 0,1746329 0,19479219 ! BMP signaling pathway GO:0030509 64 32 0,000 0,1746329 0,19470193 ! hindbrain development GO:0030902 61 32 0,000 0,1746329 0,19461174 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,1746329 0,19452165 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,1746329 0,19443163 ! gene silencing GO:0016458 65 32 0,000 0,1746329 0,1943417 ! protein targeting to membrane GO:0006612 68 33 0,000 0,17957111 0,19974484 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,17957111 0,19965254 ! ceramide metabolic process GO:0006672 64 33 0,000 0,17957111 0,19956032 ! formation of primary germ layer GO:0001704 72 33 0,000 0,17957111 0,19946819 ! cell fate specification GO:0001708 52 33 0,000 0,17957111 0,19937614 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,17957111 0,19928418 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,17957111 0,1991923 ! adult locomotory behavior GO:0008344 59 33 0,000 0,17957111 0,1991005 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,18447994 0,20444898 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,18447994 0,20435485 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,18447994 0,20426081 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,18447994 0,20416685 ! mismatch repair GO:0006298 46 34 0,000 0,18447994 0,20407298 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,18447994 0,2039792 ! negative regulation of secretion GO:0051048 63 35 0,000 0,18935956 0,20927841 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,18935956 0,20918232 ! odontogenesis GO:0042476 66 35 0,000 0,18935956 0,20908632 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,18935956 0,20899041 ! female gonad development GO:0008585 58 35 0,000 0,18935956 0,20889459 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,18935956 0,20879885 ! calcium-mediated signaling GO:0019722 62 35 0,000 0,18935956 0,20870321 ! cytokine production GO:0001816 59 35 0,000 0,18935956 0,20860765 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,19421014 0,21385337 ! cell junction organization GO:0034330 86 36 0,000 0,19421014 0,21375554 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,19421014 0,2136578 ! positive regulation of cell development GO:0010720 80 36 0,000 0,19421014 0,21356015 ! regulation of proteolysis GO:0030162 72 36 0,000 0,19421014 0,21346259 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,19421014 0,21336512 ! aerobic respiration GO:0009060 55 36 0,000 0,19421014 0,21326773 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,19421014 0,21317044 ! RNA export from nucleus GO:0006405 56 37 0,000 0,19903186 0,21836328 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,19903186 0,21826375 ! actomyosin structure organization GO:0031032 62 37 0,000 0,19903186 0,21816431 ! organic anion transport GO:0015711 68 37 0,000 0,19903186 0,21806497 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,19903186 0,21796571 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,19903186 0,21786654 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,19903186 0,21776747 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,19903186 0,21766848 ! pigment metabolic process GO:0042440 80 37 0,000 0,19903186 0,21756959 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,20382489 0,22270785 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,20382489 0,22260676 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,20382489 0,22250576 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,20382489 0,22240485 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,20382489 0,22230403 GO:0046660|female sex differentiation, ! nucleotide catabolic process GO:0009166 61 38 0,000 0,20382489 0,2222033 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,20382489 0,22210267 ! glucan metabolic process GO:0044042 62 38 0,000 0,20382489 0,22200212 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,2085894 0,22708873 ! mammary gland development GO:0030879 86 39 0,000 0,2085894 0,22698602 ! learning GO:0007612 77 39 0,000 0,2085894 0,2268834 ! ear morphogenesis GO:0042471 60 39 0,000 0,2085894 0,22678088 ! ion transmembrane transport GO:0034220 66 39 0,000 0,2085894 0,22667845 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,2085894 0,22657611 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,2085894 0,22647387 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,2085894 0,22637171 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,21332555 0,23140724 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,21332555 0,23130296 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,21332555 0,23119877 ! feeding behavior GO:0007631 59 40 0,000 0,21332555 0,23109467 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,21803351 0,23608849 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,21803351 0,23598229 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,21803351 0,23587618 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,21803351 0,23577017 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,21803351 0,23566425 ! female gamete generation GO:0007292 61 41 0,000 0,21803351 0,23555843 ! polyol metabolic process GO:0019751 66 41 0,000 0,21803351 0,2354527 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,21803351 0,23534707 ! regulation of tube size GO:0035150 71 42 0,000 0,22271345 0,24029084 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,22271345 0,24018313 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,22271345 0,24007552 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,22271345 0,23996801 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,22271345 0,23986059 ! regulation of protein secretion GO:0050708 71 42 0,000 0,22271345 0,23975327 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,22736554 0,24465183 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,22736554 0,24454246 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,22736554 0,2444332 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,22736554 0,24432402 ! glucose transport GO:0015758 65 43 0,000 0,22736554 0,24421495 ! striated muscle contraction GO:0006941 77 43 0,000 0,22736554 0,24410598 ! phagocytosis GO:0006909 90 43 0,000 0,22736554 0,2439971 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,23198994 0,24884877 ! hexose transport GO:0008645 67 44 0,000 0,23198994 0,24873788 GO:0015749|monosaccharide transport, ! double-strand break repair GO:0006302 81 44 0,000 0,23198994 0,24862708 ! B cell differentiation GO:0030183 107 44 0,000 0,23198994 0,24851638 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,23198994 0,24840578 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,23198994 0,24829528 ! developmental growth GO:0048589 82 44 0,000 0,23198994 0,24818488 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,23658682 0,25299017 ! glycolysis GO:0006096 65 45 0,000 0,23658682 0,25287778 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,23658682 0,25276549 ! leukocyte migration GO:0050900 68 45 0,000 0,23658682 0,2526533 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,23658682 0,25254121 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,23658682 0,25242921 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,23658682 0,25231732 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,23658682 0,25220553 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,24115633 0,25696285 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,24569864 0,261687 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,24569864 0,26157121 ! JNK cascade GO:0007254 91 47 0,000 0,24569864 0,26145552 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,24569864 0,26133993 ! protein homooligomerization GO:0051260 76 47 0,000 0,24569864 0,26122445 ! mitochondrial transport GO:0006839 82 48 0,000 0,25021391 0,26590754 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,25021391 0,26579014 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,25021391 0,26567285 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,25021391 0,26555566 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,25470231 0,27020006 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,25470231 0,27008098 ! regulation of ion transport GO:0043269 77 49 0,000 0,25470231 0,269962 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,25470231 0,26984313 ! peptide metabolic process GO:0006518 76 49 0,000 0,25470231 0,26972436 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,25470231 0,2696057 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,25470231 0,26948714 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,25470231 0,26936868 ! neuromuscular process GO:0050905 99 50 0,000 0,25916398 0,27396684 ! regulation of ossification GO:0030278 117 50 0,000 0,25916398 0,27384652 ! inner ear development GO:0048839 79 50 0,000 0,25916398 0,27372631 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,26359909 0,27828846 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,26359909 0,27816641 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,26359909 0,27804446 ! chromatin remodeling GO:0006338 109 51 0,000 0,26359909 0,27792262 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,26359909 0,27780088 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,26359909 0,27767925 ! vesicle organization GO:0016050 107 51 0,000 0,26359909 0,27755773 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,2680078 0,28207645 ! membrane fusion GO:0006944 110 52 0,000 0,2680078 0,28195311 ! amino acid activation GO:0043038 92 52 0,000 0,2680078 0,28182988 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! RNA catabolic process GO:0006401 93 53 0,000 0,27239025 0,28631322 ! regulation of translational initiation GO:0006446 82 53 0,000 0,27239025 0,28618819 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,27239025 0,28606327 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,27239025 0,28593846 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,27239025 0,28581376 ! activation of phospholipase C activity GO:0007202 103 54 0,000 0,27674662 0,29025822 GO:0010863|positive regulation of phospholipase C activity, ! heterocycle catabolic process GO:0046700 85 54 0,000 0,27674662 0,29013175 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,27674662 0,29000538 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,27674662 0,28987913 ! chloride transport GO:0006821 90 55 0,000 0,28107704 0,29428693 ! glucose catabolic process GO:0006007 82 55 0,000 0,28107704 0,29415893 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,28107704 0,29403103 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,28107704 0,29390325 ! positive regulation of phospholipase activity GO:0010518 104 55 0,000 0,28107704 0,29377557 ! gastrulation GO:0007369 112 55 0,000 0,28107704 0,29364801 ! RNA elongation GO:0006354 79 55 0,000 0,28107704 0,29352056 ! nuclear export GO:0051168 97 55 0,000 0,28107704 0,29339322 ! sensory perception of smell GO:0007608 80 56 0,000 0,28538169 0,2977573 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,28538169 0,29762823 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,28538169 0,29749928 ! proton transport GO:0015992 94 56 0,000 0,28538169 0,29737044 ! regulation of phospholipase activity GO:0010517 106 57 0,000 0,2896607 0,30169854 ! hydrogen transport GO:0006818 97 58 0,000 0,29391422 0,30599638 ! adult behavior GO:0030534 99 58 0,000 0,29391422 0,30586402 ! positive regulation of lipase activity GO:0060193 108 58 0,000 0,29391422 0,30573179 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,29814242 0,30999597 ! regulation of heart contraction GO:0008016 110 60 0,000 0,30234544 0,3142303 ! protein amino acid autophosphorylation GO:0046777 141 60 0,000 0,30234544 0,31409462 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,30234544 0,31395906 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,30652343 0,31816021 ! mesoderm development GO:0007498 119 61 0,000 0,30652343 0,31802302 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,30652343 0,31788594 ! ear development GO:0043583 103 62 0,000 0,31067654 0,32205418 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,31067654 0,32191548 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,31480491 0,32605278 ! detection of external stimulus GO:0009581 91 63 0,000 0,31480491 0,32591249 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,31480491 0,32577231 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,31890869 0,32987718 ! cell redox homeostasis GO:0045454 102 64 0,000 0,31890869 0,32973542 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,31890869 0,32959378 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,31890869 0,32945226 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,31890869 0,32931087 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,32298804 0,33338019 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,32298804 0,33323723 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,32704308 0,33727632 ! extracellular matrix organization GO:0030198 133 66 0,000 0,32704308 0,33713181 ! secondary metabolic process GO:0019748 116 66 0,000 0,32704308 0,33698743 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,33107397 0,34099485 ! activation of MAPK activity GO:0000187 115 67 0,000 0,33107397 0,34084894 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,33107397 0,34070315 ! hexose catabolic process GO:0019320 104 67 0,000 0,33107397 0,34055749 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 0,000 0,33107397 0,34041195 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,33107397 0,34026654 ! amino acid transport GO:0006865 125 68 0,000 0,33508085 0,34423762 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,33508085 0,3440907 ! regulation of lipase activity GO:0060191 130 68 0,000 0,33508085 0,34394391 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,33508085 0,34379723 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,33906386 0,34773557 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,33906386 0,3475874 ! antigen processing and presentation GO:0019882 104 69 0,000 0,33906386 0,34743937 ! amine catabolic process GO:0009310 117 71 0,000 0,34695883 0,35537801 ! humoral immune response GO:0006959 109 71 0,000 0,34695883 0,35522679 ! B cell activation GO:0042113 160 71 0,000 0,34695883 0,35507569 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,34695883 0,35492472 ! regulation of immune effector process GO:0002697 137 71 0,000 0,34695883 0,35477388 ! acute inflammatory response GO:0002526 113 72 0,000 0,35087108 0,35862184 ! carbohydrate transport GO:0008643 110 72 0,000 0,35087108 0,35846956 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,35087108 0,35831741 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,35087108 0,35816539 ! regulation of blood pressure GO:0008217 125 73 0,000 0,35476002 0,3619816 ! axon guidance GO:0007411 139 73 0,000 0,35476002 0,36182815 ! transition metal ion transport GO:0000041 126 74 0,000 0,35862579 0,36561595 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,35862579 0,3654611 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,36246853 0,36922069 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,36246853 0,36906444 ! rhythmic process GO:0048511 128 75 0,000 0,36246853 0,36890832 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,36628837 0,3726384 ! defense response to bacterium GO:0042742 89 76 0,000 0,36628837 0,3724809 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,36628837 0,37232354 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,37008545 0,37602432 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,37008545 0,37586559 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,3738599 0,37953879 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,3738599 0,37937871 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,37761187 0,38302452 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,37761187 0,38286311 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,37761187 0,38270183 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,37761187 0,3825407 ! protein import into nucleus GO:0006606 158 80 0,000 0,38134147 0,38615639 ! inorganic anion transport GO:0015698 138 80 0,000 0,38134147 0,38599393 ! nuclear import GO:0051170 161 81 0,000 0,38504885 0,38958265 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,39603895 0,40053371 ! nucleosome assembly GO:0006334 122 85 0,000 0,39965873 0,40402475 ! chromatin assembly GO:0031497 124 86 0,000 0,40325694 0,40749105 ! alcohol catabolic process GO:0046164 130 86 0,000 0,40325694 0,40731998 ! amine transport GO:0015837 155 86 0,000 0,40325694 0,40714905 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,4068337 0,41058804 ! protein localization in nucleus GO:0034504 176 87 0,000 0,4068337 0,41041589 ! regulation of neurological system process GO:0031644 148 88 0,000 0,41038914 0,41382912 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,41038914 0,41365575 ! cellular defense response GO:0006968 114 89 0,000 0,41392339 0,41704342 ! ossification GO:0001503 188 90 0,000 0,41743657 0,42040703 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,41743657 0,42023113 ! bone development GO:0060348 189 91 0,000 0,42092881 0,42356952 ! nucleosome organization GO:0034728 138 92 0,000 0,42440023 0,42688418 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,42440023 0,42670579 ! vitamin metabolic process GO:0006766 139 92 0,000 0,42440023 0,42652755 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,42785095 0,42981603 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,42785095 0,42963664 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,4312811 0,43290043 ! female pregnancy GO:0007565 164 94 0,000 0,4312811 0,43271991 ! transcription initiation GO:0006352 153 94 0,000 0,4312811 0,43253953 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,4346908 0,43577753 ! mRNA transport GO:0051028 169 96 0,000 0,43808017 0,43899246 ! detection of stimulus GO:0051606 151 96 0,000 0,43808017 0,4388097 ! protein ubiquitination GO:0016567 217 97 0,000 0,44144933 0,44200045 ! response to virus GO:0009615 160 98 0,000 0,4447984 0,44516845 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,4447984 0,44498335 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,4481275 0,4481275