pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6515-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of fibroblast proliferation GO:0048145 35 22 3,000 4,52E-07 1,04E-03 ! amyloid precursor protein catabolic process GO:0042987 9 6 2,000 4,649E-07 5,347E-04 ! protein oligomerization GO:0051259 100 65 4,000 1,251E-06 9,589E-04 ! amyloid precursor protein metabolic process GO:0042982 12 8 2,000 1,296E-06 7,454E-04 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 1,296E-06 5,964E-04 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 2,000 2,767E-06 1,061E-03 ! membrane protein proteolysis GO:0033619 18 11 2,000 3,796E-06 1,247E-03 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of epithelial cell proliferation GO:0050678 71 39 3,000 4,9E-06 1,409E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 4,000 5,036E-06 1,287E-03 ! glycoprotein catabolic process GO:0006516 19 12 2,000 5,051E-06 1,162E-03 ! interphase GO:0051325 159 88 4,000 5,64E-06 1,179E-03 ! positive regulation of protein import into nucleus GO:0042307 23 13 2,000 6,553E-06 1,256E-03 ! protein amino acid autophosphorylation GO:0046777 80 45 3,000 8,762E-06 1,55E-03 ! response to UV GO:0009411 75 46 3,000 9,576E-06 1,573E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 1,451E-05 2,225E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 2,000 1,545E-05 2,221E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 1,545E-05 2,091E-03 ! positive regulation of fibroblast proliferation GO:0048146 27 19 2,000 2,193E-05 2,802E-03 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 2,193E-05 2,655E-03 ! positive regulation of intracellular transport GO:0032388 29 19 2,000 2,193E-05 2,522E-03 ! negative regulation of protein kinase activity GO:0006469 99 57 3,000 2,264E-05 2,479E-03 ! negative regulation of kinase activity GO:0033673 100 58 3,000 2,426E-05 2,537E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 2,575E-05 2,575E-03 ! negative regulation of transferase activity GO:0051348 105 61 3,000 2,965E-05 2,842E-03 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 2,000 2,998E-05 2,758E-03 ! cellular response to extracellular stimulus GO:0031668 32 21 2,000 2,998E-05 2,652E-03 ! protein tetramerization GO:0051262 39 22 2,000 3,464E-05 2,951E-03 ! positive regulation of cell adhesion GO:0045785 37 23 2,000 3,975E-05 3,265E-03 ! regulation of transcription factor import into nucleus GO:0042990 46 23 2,000 3,975E-05 3,153E-03 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 4,534E-05 3,476E-03 ! regulation of protein import into nucleus GO:0042306 53 29 2,000 8,101E-05 6,011E-03 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 8,297E-05 5,964E-03 ! positive regulation of glycolysis GO:0045821 11 5 1,000 8,297E-05 5,783E-03 ! lymph vessel development GO:0001945 7 5 1,000 8,297E-05 5,613E-03 ! microvillus organization GO:0032528 7 5 1,000 8,297E-05 5,453E-03 GO:0030033|microvillus assembly, ! early endosome to late endosome transport GO:0045022 11 5 1,000 8,297E-05 5,301E-03 ! cranial nerve morphogenesis GO:0021602 6 5 1,000 8,297E-05 5,158E-03 ! regulation of respiratory burst GO:0060263 8 5 1,000 8,297E-05 5,022E-03 ! negative regulation of osteoblast differentiation GO:0045668 5 5 1,000 8,297E-05 4,893E-03 ! positive regulation of MAP kinase activity GO:0043406 121 85 3,000 1,093E-04 6,283E-03 ! cell cycle arrest GO:0007050 150 86 3,000 1,144E-04 6,415E-03 ! regulation of helicase activity GO:0051095 11 6 1,000 1,242E-04 6,803E-03 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 1,242E-04 6,645E-03 ! activation of MAPKKK activity GO:0000185 10 6 1,000 1,242E-04 6,494E-03 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 1,242E-04 6,35E-03 ! ER overload response GO:0006983 7 6 1,000 1,242E-04 6,211E-03 ! male sex determination GO:0030238 9 6 1,000 1,242E-04 6,079E-03 ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 1,242E-04 5,953E-03 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 1,313E-04 6,164E-03 ! Notch signaling pathway GO:0007219 56 35 2,000 1,433E-04 6,593E-03 ! regulation of intracellular protein transport GO:0033157 59 35 2,000 1,433E-04 6,464E-03 ! protein homooligomerization GO:0051260 52 35 2,000 1,433E-04 6,34E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 1,736E-04 7,533E-03 ! protein heterooligomerization GO:0051291 10 7 1,000 1,736E-04 7,394E-03 ! G1 DNA damage checkpoint GO:0031571 18 7 1,000 1,736E-04 7,26E-03 ! B cell lineage commitment GO:0002326 17 7 1,000 1,736E-04 7,13E-03 ! T cell lineage commitment GO:0002360 12 7 1,000 1,736E-04 7,005E-03 ! response to tumor cell GO:0002347 12 7 1,000 1,736E-04 6,884E-03 ! positive regulation of ATPase activity GO:0032781 10 7 1,000 1,736E-04 6,767E-03 ! response to light stimulus GO:0009416 153 96 3,000 1,751E-04 6,712E-03 ! induction of apoptosis by intracellular signals GO:0008629 67 40 2,000 2,142E-04 8,075E-03 ! T cell differentiation GO:0030217 65 40 2,000 2,142E-04 7,944E-03 ! positive regulation of protein transport GO:0051222 55 40 2,000 2,142E-04 7,818E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 2,31E-04 8,303E-03 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 2,31E-04 8,175E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 2,31E-04 8,051E-03 ! endothelial cell differentiation GO:0045446 14 8 1,000 2,31E-04 7,931E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 2,31E-04 7,814E-03 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 1,000 2,31E-04 7,701E-03 ! regulation of embryonic development GO:0045995 16 8 1,000 2,31E-04 7,591E-03 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 2,000 2,478E-04 8,028E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 2,659E-04 8,492E-03 ! regulation of gene-specific transcription GO:0032583 69 43 2,000 2,659E-04 8,376E-03 ! response to insulin stimulus GO:0032868 63 43 2,000 2,659E-04 8,263E-03 ! regulation of mast cell proliferation GO:0070666 64 44 2,000 2,847E-04 8,731E-03 ! regulation of developmental growth GO:0048638 13 9 1,000 2,965E-04 8,973E-03 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 2,965E-04 8,856E-03 ! regulation of glycolysis GO:0006110 15 9 1,000 2,965E-04 8,742E-03 ! receptor clustering GO:0043113 15 9 1,000 2,965E-04 8,632E-03 ! motor axon guidance GO:0008045 14 9 1,000 2,965E-04 8,524E-03 ! detection of calcium ion GO:0005513 13 9 1,000 2,965E-04 8,419E-03 ! localization within membrane GO:0051668 15 9 1,000 2,965E-04 8,316E-03 ! regulation of leukocyte proliferation GO:0070663 71 47 2,000 3,464E-04 9,6E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of DNA replication GO:0006275 75 48 2,000 3,688E-04 0,01009767 ! regulation of B cell proliferation GO:0030888 15 10 1,000 3,699E-04 0,01000944 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 3,699E-04 9,893E-03 ! response to X-ray GO:0010165 16 10 1,000 3,699E-04 9,779E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 1,000 3,699E-04 9,668E-03 ! cranial nerve development GO:0021545 12 10 1,000 3,699E-04 9,56E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 3,699E-04 9,453E-03 GO:0043470|regulation of carbohydrate catabolic process, ! cytoplasmic sequestering of protein GO:0051220 14 10 1,000 3,699E-04 9,349E-03 ! regulation of intracellular transport GO:0032386 78 49 2,000 3,92E-04 9,801E-03 ! positive regulation of cell migration GO:0030335 92 51 2,000 4,413E-04 0,01091396 ! virus-host interaction GO:0019048 17 11 1,000 4,513E-04 0,0110418 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 4,513E-04 0,01092557 ! dopamine receptor signaling pathway GO:0007212 22 11 1,000 4,513E-04 0,01081176 ! regulation of intracellular pH GO:0051453 17 11 1,000 4,513E-04 0,0107003 ! actin cytoskeleton reorganization GO:0031532 21 11 1,000 4,513E-04 0,01059111 ! negative regulation of mast cell proliferation GO:0070667 17 11 1,000 4,513E-04 0,01048413 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 5,405E-04 0,01243191 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 5,405E-04 0,01230882 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! histone acetylation GO:0016573 23 12 1,000 5,405E-04 0,01218815 ! autonomic nervous system development GO:0048483 23 12 1,000 5,405E-04 0,01206982 ! peptidyl-lysine modification GO:0018205 18 12 1,000 5,405E-04 0,01195376 ! response to gamma radiation GO:0010332 20 12 1,000 5,405E-04 0,01183991 ! positive regulation of cell motion GO:0051272 99 56 2,000 5,814E-04 0,01261571 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 6,125E-04 0,01316509 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 6,376E-04 0,01357857 ! regulation of exocytosis GO:0017157 17 13 1,000 6,376E-04 0,01345399 ! regulation of cellular pH GO:0030641 20 13 1,000 6,376E-04 0,01333168 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 6,376E-04 0,01321158 ! regulation of calcium-mediated signaling GO:0050848 18 13 1,000 6,376E-04 0,01309362 ! protein maturation by peptide bond cleavage GO:0051605 76 58 2,000 6,445E-04 0,01311909 ! G1 phase of mitotic cell cycle GO:0000080 23 14 1,000 7,425E-04 0,0149799 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 7,425E-04 0,01484964 ! activation of MAPKK activity GO:0000186 21 14 1,000 7,425E-04 0,01472163 ! cellular response to starvation GO:0009267 21 14 1,000 7,425E-04 0,0145958 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 7,425E-04 0,01447211 ! G1/S transition checkpoint GO:0031575 33 14 1,000 7,425E-04 0,0143505 ! regulation of erythrocyte differentiation GO:0045646 27 14 1,000 7,425E-04 0,01423091 ! regulation of ATPase activity GO:0043462 18 14 1,000 7,425E-04 0,0141133 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 7,425E-04 0,01399761 ! epithelial to mesenchymal transition GO:0001837 22 14 1,000 7,425E-04 0,01388381 ! negative regulation of cell growth GO:0030308 106 62 2,000 7,836E-04 0,01453383 ! regulation of transcription factor activity GO:0051090 97 63 2,000 8,211E-04 0,01510743 GO:0090046|regulation of transcription regulator activity, ! lipid phosphorylation GO:0046834 23 15 1,000 8,551E-04 0,0156092 ! centrosome cycle GO:0007098 16 15 1,000 8,551E-04 0,0154863 ! negative regulation of leukocyte proliferation GO:0070664 25 15 1,000 8,551E-04 0,01536531 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 8,551E-04 0,0152462 ! negative regulation of cell size GO:0045792 108 64 2,000 8,597E-04 0,01520957 ! regulation of caspase activity GO:0043281 97 65 2,000 8,994E-04 0,01579139 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 9,755E-04 0,01699648 ! G1 phase GO:0051318 27 16 1,000 9,755E-04 0,01686869 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 9,755E-04 0,0167428 ! nerve development GO:0021675 18 16 1,000 9,755E-04 0,01661878 ! protein amino acid acetylation GO:0006473 28 16 1,000 9,755E-04 0,01649658 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 9,824E-04 0,0164926 ! signal complex assembly GO:0007172 29 17 1,000 1,103E-03 0,01839083 ! neuromuscular junction development GO:0007528 23 17 1,000 1,103E-03 0,01825852 ! negative regulation of protein catabolic process GO:0042177 26 17 1,000 1,103E-03 0,0181281 ! regulation of catabolic process GO:0009894 106 70 2,000 1,116E-03 0,01819889 ! lymphocyte differentiation GO:0030098 113 71 2,000 1,163E-03 0,01882936 ! regulation of peptidase activity GO:0052547 106 72 2,000 1,211E-03 0,0194707 ! positive regulation of DNA replication GO:0045740 29 18 1,000 1,239E-03 0,01979066 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 1,000 1,239E-03 0,01965418 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 1,239E-03 0,01951956 ! somitogenesis GO:0001756 24 18 1,000 1,239E-03 0,01938677 ! detection of chemical stimulus GO:0009593 26 18 1,000 1,239E-03 0,01925578 ! cellular response to nutrient levels GO:0031669 27 18 1,000 1,239E-03 0,01912655 ! negative regulation of T cell activation GO:0050868 25 18 1,000 1,239E-03 0,01899904 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 1,239E-03 0,01887322 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 1,31E-03 0,01982865 ! negative regulation of growth GO:0045926 123 75 2,000 1,362E-03 0,02047787 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 1,382E-03 0,02064415 GO:0010675|regulation of cellular carbohydrate metabolic process, ! negative regulation of epithelial cell proliferation GO:0050680 34 19 1,000 1,382E-03 0,02051096 ! response to starvation GO:0042594 30 19 1,000 1,382E-03 0,02037948 ! sex determination GO:0007530 29 19 1,000 1,382E-03 0,02024967 ! protein stabilization GO:0050821 26 19 1,000 1,382E-03 0,02012151 ! regulation of protein transport GO:0051223 114 76 2,000 1,415E-03 0,02047296 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 119 77 2,000 1,47E-03 0,0211265 ! positive regulation of B cell activation GO:0050871 31 20 1,000 1,533E-03 0,02189977 ! T cell activation GO:0042110 134 79 2,000 1,582E-03 0,02246473 ! protein amino acid acylation GO:0043543 37 21 1,000 1,691E-03 0,02386349 ! cell aging GO:0007569 32 21 1,000 1,691E-03 0,02371798 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 1,691E-03 0,02357424 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 1,691E-03 0,02343222 ! regulation of cell adhesion GO:0030155 159 83 2,000 1,823E-03 0,02511362 ! protein import into nucleus, translocation GO:0000060 36 22 1,000 1,857E-03 0,02542117 ! microtubule organizing center organization GO:0031023 28 22 1,000 1,857E-03 0,02527075 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 1,857E-03 0,0251221 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 1,857E-03 0,02497519 ! regulation of DNA metabolic process GO:0051052 135 85 2,000 1,952E-03 0,02610475 ! anterior/posterior pattern formation GO:0009952 124 85 2,000 1,952E-03 0,02595386 ! regulation of protein localization GO:0032880 132 85 2,000 1,952E-03 0,0258047 ! myelination GO:0042552 35 23 1,000 2,03E-03 0,02667879 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 2,03E-03 0,02652721 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 2,03E-03 0,02637733 ! negative regulation of DNA replication GO:0008156 35 23 1,000 2,03E-03 0,02622915 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 2,03E-03 0,02608262 ! interaction with host GO:0051701 37 23 1,000 2,03E-03 0,02593771 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 2,03E-03 0,02579441 ! cell fate determination GO:0001709 45 23 1,000 2,03E-03 0,02565268 ! negative regulation of catabolic process GO:0009895 34 23 1,000 2,03E-03 0,0255125 ! skeletal muscle tissue development GO:0007519 123 87 2,000 2,086E-03 0,02608038 GO:0060538|skeletal muscle organ development, ! protein processing GO:0016485 114 88 2,000 2,156E-03 0,02680004 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 2,21E-03 0,02733196 ! mitochondrial membrane organization GO:0007006 39 24 1,000 2,21E-03 0,0271858 ! receptor metabolic process GO:0043112 37 24 1,000 2,21E-03 0,02704119 ! negative regulation of cell development GO:0010721 56 24 1,000 2,21E-03 0,02689811 GO:0050768|negative regulation of neurogenesis, ! base-excision repair GO:0006284 31 24 1,000 2,21E-03 0,02675655 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 2,21E-03 0,02661646 ! regulation of osteoblast differentiation GO:0045667 37 24 1,000 2,21E-03 0,02647783 ! neurotransmitter secretion GO:0007269 32 24 1,000 2,21E-03 0,02634064 ! leukocyte differentiation GO:0002521 143 90 2,000 2,298E-03 0,0272486 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 2,398E-03 0,02828475 GO:0045936|negative regulation of phosphate metabolic process, ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 2,398E-03 0,02814044 ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 2,398E-03 0,02799759 ! cell fate commitment GO:0045165 141 92 2,000 2,447E-03 0,02842245 ! peptidyl-amino acid modification GO:0018193 147 93 2,000 2,523E-03 0,0291626 ! regulation of pH GO:0006885 36 26 1,000 2,593E-03 0,02982018 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 2,593E-03 0,02967182 ! regulation of binding GO:0051098 151 95 2,000 2,68E-03 0,03051933 ! protein maturation GO:0051604 129 96 2,000 2,761E-03 0,03128464 ! response to ionizing radiation GO:0010212 47 27 1,000 2,795E-03 0,03151557 ! negative regulation of leukocyte activation GO:0002695 39 27 1,000 2,795E-03 0,03136184 ! negative regulation of transcription regulator activity GO:0090048 47 27 1,000 2,795E-03 0,0312096 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of protein transport GO:0051224 49 27 1,000 2,795E-03 0,03105883 ! ensheathment of neurons GO:0007272 43 28 1,000 3,005E-03 0,03322525 GO:0008366|axon ensheathment, ! positive regulation of catabolic process GO:0009896 40 28 1,000 3,005E-03 0,03306628 ! regulation of B cell activation GO:0050864 42 28 1,000 3,005E-03 0,03290882 ! embryonic skeletal system morphogenesis GO:0048704 42 30 1,000 3,445E-03 0,03755175 ! hindbrain development GO:0030902 45 30 1,000 3,445E-03 0,03737462 ! negative regulation of cell activation GO:0050866 44 30 1,000 3,445E-03 0,03719915 ! DNA damage checkpoint GO:0000077 53 31 1,000 3,676E-03 0,03950523 ! mammary gland development GO:0030879 57 31 1,000 3,676E-03 0,03932148 ! maintenance of protein location in cell GO:0032507 60 31 1,000 3,676E-03 0,03913944 ! segmentation GO:0035282 41 31 1,000 3,676E-03 0,03895907 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 3,676E-03 0,03878036 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 3,913E-03 0,04110031 ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 3,913E-03 0,04091349 ! peripheral nervous system development GO:0007422 53 32 1,000 3,913E-03 0,04072837 ! regulation of protein stability GO:0031647 48 32 1,000 3,913E-03 0,0405449 ! calcium-mediated signaling GO:0019722 50 32 1,000 3,913E-03 0,04036309 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 3,913E-03 0,0401829 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 1,000 4,158E-03 0,04250611 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 4,158E-03 0,04231803 ! carbohydrate homeostasis GO:0033500 39 33 1,000 4,158E-03 0,0421316 GO:0042593|glucose homeostasis, ! negative regulation of DNA binding GO:0043392 54 33 1,000 4,158E-03 0,04194682 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 4,158E-03 0,04176364 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 4,158E-03 0,04158206 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 4,41E-03 0,04390796 ! DNA integrity checkpoint GO:0031570 57 34 1,000 4,41E-03 0,04371871 ! dorsal/ventral pattern formation GO:0009953 44 34 1,000 4,41E-03 0,04353107 ! regulation of action potential in neuron GO:0019228 54 35 1,000 4,668E-03 0,04588663 ! maintenance of protein location GO:0045185 65 35 1,000 4,668E-03 0,04569137 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 4,668E-03 0,04549776 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 4,934E-03 0,04788176 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of binding GO:0051100 58 36 1,000 4,934E-03 0,04768058 ! gliogenesis GO:0042063 71 38 1,000 5,485E-03 0,05278633 ! regulation of T cell proliferation GO:0042129 58 38 1,000 5,485E-03 0,05256638 ! mesenchymal cell development GO:0014031 64 38 1,000 5,485E-03 0,05234826 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of location in cell GO:0051651 69 38 1,000 5,485E-03 0,05213195 ! synapse organization GO:0050808 55 39 1,000 5,771E-03 0,05462221 ! response to calcium ion GO:0051592 58 40 1,000 6,063E-03 0,05715517 ! double-strand break repair GO:0006302 67 40 1,000 6,063E-03 0,05692188 ! B cell differentiation GO:0030183 62 40 1,000 6,063E-03 0,05669049 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 6,063E-03 0,05646098 ! endosome transport GO:0016197 71 41 1,000 6,363E-03 0,05900741 ! positive regulation of DNA binding GO:0043388 57 41 1,000 6,363E-03 0,05877043 ! regulation of T cell differentiation GO:0045580 59 41 1,000 6,363E-03 0,05853535 ! mitochondrial transport GO:0006839 60 42 1,000 6,668E-03 0,06110371 ! embryonic skeletal system development GO:0048706 56 42 1,000 6,668E-03 0,06086123 ! positive regulation of binding GO:0051099 59 43 1,000 6,981E-03 0,06345989 ! activation of caspase activity GO:0006919 65 43 1,000 6,981E-03 0,06321004 ! regulation of action potential GO:0001508 71 44 1,000 7,299E-03 0,06583807 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 1,000 7,299E-03 0,06558089 ! positive regulation of cell cycle GO:0045787 77 45 1,000 7,625E-03 0,0682374 ! regulation of ossification GO:0030278 71 46 1,000 7,957E-03 0,0709309 ! histone modification GO:0016570 68 46 1,000 7,957E-03 0,07065703 ! covalent chromatin modification GO:0016569 75 47 1,000 8,295E-03 0,0733773 ! negative regulation of immune system process GO:0002683 73 47 1,000 8,295E-03 0,07309616 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 8,295E-03 0,07281717 ! positive regulation of caspase activity GO:0043280 72 48 1,000 8,639E-03 0,075554 GO:0010952|positive regulation of peptidase activity, ! heart morphogenesis GO:0003007 65 48 1,000 8,639E-03 0,07526781 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 8,639E-03 0,07498378 ! regulation of angiogenesis GO:0045765 94 49 1,000 8,99E-03 0,07773645 ! integrin-mediated signaling pathway GO:0007229 81 49 1,000 8,99E-03 0,0774453 ! maintenance of location GO:0051235 84 49 1,000 8,99E-03 0,07715633 ! skeletal muscle fiber development GO:0048741 73 50 1,000 9,348E-03 0,07992412 ! lipid modification GO:0030258 73 50 1,000 9,348E-03 0,07962811 ! positive regulation of growth GO:0045927 67 50 1,000 9,348E-03 0,07933428 ! activation of phospholipase C activity GO:0007202 87 51 1,000 9,711E-03 0,08211652 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 9,711E-03 0,08181573 ! regulation of protein catabolic process GO:0042176 77 51 1,000 9,711E-03 0,08151713 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,01008092 0,08431318 ! aging GO:0007568 79 52 1,000 0,01008092 0,0840077 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,01008092 0,08370442 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,01045687 0,08651364 ! regulation of neurotransmitter levels GO:0001505 73 53 1,000 0,01045687 0,08620356 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,01045687 0,08589569 ! cell projection assembly GO:0030031 76 53 1,000 0,01045687 0,08559001 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,01083896 0,08840288 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,01083896 0,0880905 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,01083896 0,08778032 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 0,01162146 0,09378721 ! chromosome segregation GO:0007059 83 57 1,000 0,01202179 0,09667869 ! viral reproductive process GO:0022415 87 58 1,000 0,01242812 0,09959814 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 0,01242812 0,09925231 ! activation of MAPK activity GO:0000187 84 59 1,000 0,01284041 0,10219012 ! lung development GO:0030324 94 59 1,000 0,01284041 0,10183774 ! actin filament organization GO:0007015 95 59 1,000 0,01284041 0,10148779 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 1,000 0,01325864 0,10443446 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,01325864 0,10407803 ! regulation of vesicle-mediated transport GO:0060627 79 60 1,000 0,01325864 0,10372402 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,01325864 0,10337242 ! cell-matrix adhesion GO:0007160 114 61 1,000 0,01368275 0,10631869 ! neurotransmitter transport GO:0006836 81 62 1,000 0,01411273 0,10929047 ! respiratory tube development GO:0030323 99 62 1,000 0,01411273 0,10892373 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01450322 0,11156326 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01450322 0,11119138 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01450322 0,11082198 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01450322 0,11045502 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01450322 0,11009048 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01450322 0,10972834 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01450322 0,10936857 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01450322 0,10901116 ! sleep GO:0030431 11 5 0,000 0,01450322 0,10865607 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01450322 0,10830329 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01450322 0,1079528 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01450322 0,10760456 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01450322 0,10725857 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01450322 0,10691479 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01450322 0,10657321 ! tongue development GO:0043586 6 5 0,000 0,01450322 0,1062338 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01450322 0,10589655 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01450322 0,10556144 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01450322 0,10522844 ! cobalt ion transport GO:0006824 9 5 0,000 0,01450322 0,10489753 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01450322 0,1045687 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01450322 0,10424192 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01450322 0,10391718 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01450322 0,10359446 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01450322 0,10327373 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,01450322 0,10295498 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01450322 0,1026382 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01450322 0,10232336 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01450322 0,10201044 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01450322 0,10169943 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01450322 0,10139032 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01450322 0,10108307 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01450322 0,10077769 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01450322 0,10047414 ! malate metabolic process GO:0006108 7 5 0,000 0,01450322 0,10017242 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01450322 0,0998725 ! behavioral response to pain GO:0048266 7 5 0,000 0,01450322 0,09957437 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01450322 0,09927802 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01450322 0,09898343 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01450322 0,09869058 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01450322 0,09839945 ! mating behavior GO:0007617 6 5 0,000 0,01450322 0,09811004 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01450322 0,09782233 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01450322 0,0975363 ! rhythmic behavior GO:0007622 12 5 0,000 0,01450322 0,09725194 ! copulation GO:0007620 7 5 0,000 0,01450322 0,09696923 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01450322 0,09668816 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01450322 0,09640871 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01450322 0,09613088 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01450322 0,09585464 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01450322 0,09557998 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01450322 0,0953069 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01450322 0,09503537 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01450322 0,09476538 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01450322 0,09449693 ! response to protozoan GO:0001562 9 5 0,000 0,01450322 0,09422998 ! endochondral ossification GO:0001958 12 5 0,000 0,01450322 0,09396455 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01450322 0,0937006 ! parathyroid gland development GO:0060017 8 5 0,000 0,01450322 0,09343814 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01450322 0,09317714 ! anagen GO:0042640 6 5 0,000 0,01450322 0,09291759 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01450322 0,09265948 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01450322 0,09240281 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01450322 0,09214755 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01450322 0,0918937 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01450322 0,09164125 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01450322 0,09139018 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01450322 0,09114048 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01450322 0,09089214 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01450322 0,09064515 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01450322 0,0903995 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01450322 0,09015517 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01450322 0,08991217 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,01450322 0,08967047 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01450322 0,08943007 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01450322 0,08919095 ! ovulation GO:0030728 6 5 0,000 0,01450322 0,08895311 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01450322 0,08871653 GO:0033135|regulation of peptidyl-serine phosphorylation, ! valine metabolic process GO:0006573 8 5 0,000 0,01450322 0,08848121 ! response to pH GO:0009268 9 5 0,000 0,01450322 0,08824713 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01450322 0,08801429 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01450322 0,08778267 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01450322 0,08755227 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01450322 0,08732307 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01450322 0,08709508 ! polyol catabolic process GO:0046174 7 5 0,000 0,01450322 0,08686827 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01450322 0,08664264 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01450322 0,08641817 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01450322 0,08619487 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01450322 0,08597272 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01450322 0,08575171 ! urea metabolic process GO:0019627 6 5 0,000 0,01450322 0,08553183 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01450322 0,08531308 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01450322 0,08509545 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01450322 0,08487892 ! neutrophil activation GO:0042119 5 5 0,000 0,01450322 0,08466349 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01450322 0,08444915 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01450322 0,0842359 ! response to food GO:0032094 5 5 0,000 0,01450322 0,08402371 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01450322 0,0838126 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01450322 0,08360254 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01450322 0,08339354 ! forebrain neuron development GO:0021884 7 5 0,000 0,01450322 0,08318557 ! melanosome organization GO:0032438 7 5 0,000 0,01450322 0,08297864 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01450322 0,08277274 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01450322 0,08256786 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01450322 0,08236399 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01450322 0,08216112 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01450322 0,08195925 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01450322 0,08175837 ! nucleoside transport GO:0015858 6 5 0,000 0,01450322 0,08155847 ! nucleoside salvage GO:0043174 7 5 0,000 0,01450322 0,08135955 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01450322 0,08116159 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01450322 0,0809646 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01450322 0,08076856 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01450322 0,08057347 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01450322 0,08037931 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01450322 0,08018609 ! depyrimidination GO:0045008 8 5 0,000 0,01450322 0,0799938 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01450322 0,07980243 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01450322 0,07961197 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01450322 0,07942242 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01450322 0,07923376 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01450322 0,07904601 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01450322 0,07885914 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01450322 0,07867315 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01450322 0,07848803 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01450322 0,07830379 ! monocyte differentiation GO:0030224 8 5 0,000 0,01450322 0,07812041 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01450322 0,07793788 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01450322 0,07775621 ! centrosome duplication GO:0051298 5 5 0,000 0,01450322 0,07757538 ! response to UV-C GO:0010225 6 5 0,000 0,01450322 0,07739539 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01450322 0,07721624 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01450322 0,07703791 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01450322 0,0768604 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01450322 0,07668371 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01450322 0,07650783 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01450322 0,07633276 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01450322 0,07615848 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01450322 0,075985 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01450322 0,07581231 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01450322 0,0756404 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01450322 0,07546926 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01450322 0,0752989 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01450322 0,07512931 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01450322 0,07496048 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01450322 0,07479241 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01450322 0,07462509 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01450322 0,07445851 ! neural tube patterning GO:0021532 6 5 0,000 0,01450322 0,07429268 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01450322 0,07412759 ! histone demethylation GO:0016577 9 5 0,000 0,01450322 0,07396323 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01450322 0,07379959 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01450322 0,07363668 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01450322 0,07347448 ! enteric nervous system development GO:0048484 8 5 0,000 0,01450322 0,073313 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01450322 0,07315222 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01450322 0,07299215 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01450322 0,07283278 ! transcription termination GO:0006353 8 5 0,000 0,01450322 0,07267411 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01450322 0,07251612 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01450322 0,07235882 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01450322 0,0722022 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01450322 0,07204625 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01450322 0,07189098 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01450322 0,07173638 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01450322 0,07158243 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01450322 0,07142915 ! apical protein localization GO:0045176 6 5 0,000 0,01450322 0,07127653 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01450322 0,07112455 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01450322 0,07097322 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01450322 0,07082254 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01450322 0,07067249 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01450322 0,07052308 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01450322 0,07037429 ! glial cell migration GO:0008347 10 5 0,000 0,01450322 0,07022614 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01450322 0,0700786 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01450322 0,06993169 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01450322 0,06978539 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01450322 0,0696397 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01450322 0,06949461 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01450322 0,06935013 ! neural plate development GO:0001840 6 5 0,000 0,01450322 0,06920625 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,01450322 0,06906297 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01450322 0,06892028 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01450322 0,06877817 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01450322 0,06863666 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01450322 0,06849572 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01450322 0,06835536 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01450322 0,06821557 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01450322 0,06807636 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01450322 0,06793771 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01450322 0,06779962 ! spindle assembly GO:0051225 5 5 0,000 0,01450322 0,0676621 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01450322 0,06752513 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01450322 0,06738872 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01450322 0,06725285 ! organ regeneration GO:0031100 7 5 0,000 0,01450322 0,06711753 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01450322 0,06698276 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01450322 0,06684853 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,01450322 0,06671483 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01450322 0,06658167 GO:0055081|anion homeostasis, ! cAMP-mediated signaling GO:0019933 97 63 1,000 0,01454852 0,06665656 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 0,01454852 0,06652404 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,01454852 0,06639205 ! viral reproduction GO:0016032 92 63 1,000 0,01454852 0,06626058 ! regulation of lipase activity GO:0060191 109 63 1,000 0,01454852 0,06612963 ! cell cycle checkpoint GO:0000075 108 64 1,000 0,01499009 0,0680024 ! respiratory system development GO:0060541 100 64 1,000 0,01499009 0,06786854 ! B cell activation GO:0042113 104 65 1,000 0,01543742 0,0697565 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,01589045 0,07166282 ! axon guidance GO:0007411 99 66 1,000 0,01589045 0,07152258 ! learning or memory GO:0007611 123 68 1,000 0,01681351 0,07552944 ! activation of protein kinase activity GO:0032147 102 69 1,000 0,01728347 0,07748922 ! response to drug GO:0042493 108 69 1,000 0,01728347 0,07733846 ! tRNA transcription GO:0009304 11 6 0,000 0,01737902 0,07761505 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,01737902 0,07746464 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,01737902 0,0773148 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,01737902 0,07716554 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01737902 0,07701686 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,01737902 0,07686875 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,01737902 0,07672121 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,01737902 0,07657424 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,01737902 0,07642782 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,01737902 0,07628197 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,01737902 0,07613667 ! prostate gland development GO:0030850 9 6 0,000 0,01737902 0,07599192 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,01737902 0,07584773 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,01737902 0,07570408 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,01737902 0,07556097 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,01737902 0,0754184 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,01737902 0,07527637 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,01737902 0,07513487 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,01737902 0,07499391 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,01737902 0,07485347 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,01737902 0,07471355 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,01737902 0,07457416 ! neuron adhesion GO:0007158 9 6 0,000 0,01737902 0,07443529 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,01737902 0,07429694 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,01737902 0,07415909 ! signal peptide processing GO:0006465 8 6 0,000 0,01737902 0,07402176 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,01737902 0,07388494 ! mRNA stabilization GO:0048255 15 6 0,000 0,01737902 0,07374862 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,01737902 0,0736128 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,01737902 0,07347748 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,01737902 0,07334266 ! opsonization GO:0008228 8 6 0,000 0,01737902 0,07320834 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,01737902 0,0730745 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,01737902 0,07294115 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,01737902 0,07280829 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,01737902 0,07267591 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,01737902 0,07254401 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01737902 0,07241259 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,01737902 0,07228165 ! mechanosensory behavior GO:0007638 8 6 0,000 0,01737902 0,07215118 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,01737902 0,07202117 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,01737902 0,07189164 ! response to interferon-gamma GO:0034341 12 6 0,000 0,01737902 0,07176257 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,01737902 0,07163396 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,01737902 0,07150582 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01737902 0,07137813 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,01737902 0,07125089 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,01737902 0,07112411 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,01737902 0,07099778 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,01737902 0,0708719 ! thymic T cell selection GO:0045061 12 6 0,000 0,01737902 0,07074646 ! protein lipoylation GO:0009249 10 6 0,000 0,01737902 0,07062147 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,01737902 0,07049692 ! pigment granule organization GO:0048753 11 6 0,000 0,01737902 0,0703728 ! drug transport GO:0015893 6 6 0,000 0,01737902 0,07024912 ! cysteine metabolic process GO:0006534 7 6 0,000 0,01737902 0,07012588 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,01737902 0,07000307 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01737902 0,06988068 ! histidine metabolic process GO:0006547 6 6 0,000 0,01737902 0,06975873 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,01737902 0,0696372 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,01737902 0,06951609 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,01737902 0,0693954 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,01737902 0,06927513 ! adenohypophysis development GO:0021984 10 6 0,000 0,01737902 0,06915528 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,01737902 0,06903584 ! hyperosmotic response GO:0006972 8 6 0,000 0,01737902 0,06891681 ! microtubule nucleation GO:0007020 10 6 0,000 0,01737902 0,0687982 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,01737902 0,06867999 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,01737902 0,06856218 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,01737902 0,06844478 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,01737902 0,06832778 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,01737902 0,06821118 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,01737902 0,06809498 ! response to dietary excess GO:0002021 7 6 0,000 0,01737902 0,06797917 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,01737902 0,06786376 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,01737902 0,06774873 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,01737902 0,0676341 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,01737902 0,06751985 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,01737902 0,06740599 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,01737902 0,06729251 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01737902 0,06717941 ! neuron apoptosis GO:0051402 8 6 0,000 0,01737902 0,0670667 ! organic alcohol transport GO:0015850 9 6 0,000 0,01737902 0,06695436 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,01737902 0,06684239 ! T cell mediated immunity GO:0002456 12 6 0,000 0,01737902 0,0667308 ! carnitine transport GO:0015879 8 6 0,000 0,01737902 0,06661959 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,01737902 0,06650874 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,01737902 0,06639826 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01737902 0,06628815 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,01737902 0,0661784 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,01737902 0,06606901 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,01737902 0,06595999 ! parturition GO:0007567 12 6 0,000 0,01737902 0,06585132 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,01737902 0,06574301 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,01737902 0,06563506 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,01737902 0,06552746 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,01737902 0,06542022 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,01737902 0,06531332 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,01737902 0,06520677 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,01737902 0,06510057 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,01737902 0,06499472 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,01737902 0,06488921 ! macrophage differentiation GO:0030225 10 6 0,000 0,01737902 0,06478404 ! astrocyte development GO:0014002 14 6 0,000 0,01737902 0,06467921 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,01737902 0,06457472 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,01737902 0,06447057 ! interaction with symbiont GO:0051702 8 6 0,000 0,01737902 0,06436675 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,01737902 0,06426327 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01737902 0,06416012 ! eating behavior GO:0042755 6 6 0,000 0,01737902 0,06405729 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,01737902 0,0639548 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,01737902 0,06385264 ! response to copper ion GO:0046688 9 6 0,000 0,01737902 0,0637508 ! DNA topological change GO:0006265 8 6 0,000 0,01737902 0,06364929 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,01737902 0,0635481 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,01737902 0,06344723 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,01737902 0,06334667 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01737902 0,06324644 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01737902 0,06314653 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,01737902 0,06304693 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,01737902 0,06294764 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,01737902 0,06284867 ! gas homeostasis GO:0033483 11 6 0,000 0,01737902 0,06275 ! hair follicle maturation GO:0048820 7 6 0,000 0,01737902 0,06265165 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,01737902 0,0625536 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,01737902 0,06245586 ! Schwann cell development GO:0014044 14 6 0,000 0,01737902 0,06235843 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,01737902 0,0622613 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,01737902 0,06216447 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01737902 0,06206794 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,01737902 0,06197171 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,01737902 0,06187578 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,01737902 0,06178014 ! histone ubiquitination GO:0016574 7 6 0,000 0,01737902 0,0616848 ! regulation of meiosis GO:0040020 10 6 0,000 0,01737902 0,06158976 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,01737902 0,061495 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,01737902 0,06140054 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,01737902 0,06130637 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,01737902 0,06121248 ! membrane to membrane docking GO:0022614 12 6 0,000 0,01737902 0,06111889 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,01737902 0,06102558 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,01737902 0,06093255 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,01737902 0,0608398 ! receptor internalization GO:0031623 9 6 0,000 0,01737902 0,06074734 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,01737902 0,06065516 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,01737902 0,06056326 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01737902 0,06047164 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,01737902 0,06038029 ! protein deubiquitination GO:0016579 8 6 0,000 0,01737902 0,06028922 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,01737902 0,06019842 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,01737902 0,0601079 ! axonal fasciculation GO:0007413 9 6 0,000 0,01737902 0,06001765 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,01737902 0,05992766 ! thiamin metabolic process GO:0006772 6 6 0,000 0,01737902 0,05983795 ! midbrain development GO:0030901 6 6 0,000 0,01737902 0,05974851 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,01737902 0,05965933 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01737902 0,05957042 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,01737902 0,05948177 ! progesterone metabolic process GO:0042448 8 6 0,000 0,01737902 0,05939339 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,01737902 0,05930527 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,01737902 0,05921741 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,01737902 0,05912981 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,01737902 0,05904247 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,01737902 0,05895539 ! adult feeding behavior GO:0008343 6 6 0,000 0,01737902 0,05886856 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,01737902 0,05878199 ! blastocyst growth GO:0001832 15 6 0,000 0,01737902 0,05869567 ! pigment granule transport GO:0051904 12 6 0,000 0,01737902 0,05860961 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,01737902 0,05852379 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,01737902 0,05843823 ! catecholamine transport GO:0051937 7 6 0,000 0,01737902 0,05835292 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01737902 0,05826786 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,01737902 0,05818304 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,01737902 0,05809848 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,01737902 0,05801415 ! protein prenylation GO:0018342 10 6 0,000 0,01737902 0,05793008 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01737902 0,05784624 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,01737902 0,05776265 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,01737902 0,0576793 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,01737902 0,05759618 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,01737902 0,05751331 ! response to metal ion GO:0010038 103 70 1,000 0,01775899 0,05868631 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,01775899 0,05860211 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,01824005 0,0601033 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,0187266 0,06161829 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 1,000 0,0187266 0,06153026 ! negative regulation of transport GO:0051051 116 73 1,000 0,01921862 0,06305682 ! mitochondrion organization GO:0007005 104 73 1,000 0,01921862 0,062967 ! response to oxygen levels GO:0070482 137 74 1,000 0,01971607 0,06450493 ! protein import into nucleus GO:0006606 118 74 1,000 0,01971607 0,06441331 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,01971607 0,06432194 ! response to inorganic substance GO:0010035 115 75 1,000 0,02021892 0,065869 ! nuclear import GO:0051170 121 75 1,000 0,02021892 0,06577583 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,02024659 0,06577283 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,02024659 0,06568006 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,02024659 0,06558756 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,02024659 0,06549531 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,02024659 0,06540332 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02024659 0,06531159 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,02024659 0,06522012 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02024659 0,0651289 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,02024659 0,06503794 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,02024659 0,06494723 ! reproductive behavior GO:0019098 12 7 0,000 0,02024659 0,06485678 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,02024659 0,06476657 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,02024659 0,06467662 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,02024659 0,06458691 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,02024659 0,06449746 ! oligopeptide transport GO:0006857 11 7 0,000 0,02024659 0,06440825 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,02024659 0,06431929 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,02024659 0,06423057 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,02024659 0,0641421 ! RNA methylation GO:0001510 11 7 0,000 0,02024659 0,06405387 ! pericardium development GO:0060039 8 7 0,000 0,02024659 0,06396589 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,02024659 0,06387814 ! fibril organization GO:0043206 13 7 0,000 0,02024659 0,06379064 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,02024659 0,06370337 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02024659 0,06361635 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,02024659 0,06352956 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,02024659 0,063443 ! lipoprotein transport GO:0042953 9 7 0,000 0,02024659 0,06335669 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,02024659 0,0632706 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02024659 0,06318476 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02024659 0,06309914 ! estrogen metabolic process GO:0008210 14 7 0,000 0,02024659 0,06301375 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,02024659 0,0629286 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,02024659 0,06284368 ! chemosensory behavior GO:0007635 9 7 0,000 0,02024659 0,06275898 ! microtubule bundle formation GO:0001578 8 7 0,000 0,02024659 0,06267452 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,02024659 0,06259028 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,02024659 0,06250626 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,02024659 0,06242247 ! leukocyte degranulation GO:0043299 10 7 0,000 0,02024659 0,06233891 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,02024659 0,06225557 ! reflex GO:0060004 12 7 0,000 0,02024659 0,06217245 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02024659 0,06208955 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,02024659 0,06200688 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02024659 0,06192442 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,02024659 0,06184218 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,02024659 0,06176017 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02024659 0,06167836 ! spinal cord patterning GO:0021511 7 7 0,000 0,02024659 0,06159678 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,02024659 0,06151541 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,02024659 0,06143425 ! adrenal gland development GO:0030325 17 7 0,000 0,02024659 0,06135331 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,02024659 0,06127259 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,02024659 0,06119207 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,02024659 0,06111177 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,02024659 0,06103167 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,02024659 0,06095179 ! endosome organization GO:0007032 10 7 0,000 0,02024659 0,06087211 ! thyroid hormone generation GO:0006590 11 7 0,000 0,02024659 0,06079264 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,02024659 0,06071338 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,02024659 0,06063433 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,02024659 0,06055548 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02024659 0,06047684 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,02024659 0,0603984 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02024659 0,06032016 ! galactose metabolic process GO:0006012 10 7 0,000 0,02024659 0,06024213 ! vesicle fusion GO:0006906 15 7 0,000 0,02024659 0,0601643 ! intracellular pH reduction GO:0051452 10 7 0,000 0,02024659 0,06008666 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,02024659 0,06000923 ! organ growth GO:0035265 11 7 0,000 0,02024659 0,059932 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,02024659 0,05985497 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,02024659 0,05977813 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,02024659 0,05970149 ! retinol metabolic process GO:0042572 9 7 0,000 0,02024659 0,05962505 ! behavioral fear response GO:0001662 13 7 0,000 0,02024659 0,0595488 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,02024659 0,05947275 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,02024659 0,05939689 ! rRNA modification GO:0000154 12 7 0,000 0,02024659 0,05932123 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02024659 0,05924576 ! response to UV-B GO:0010224 11 7 0,000 0,02024659 0,05917048 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,02024659 0,05909539 ! intermediate filament organization GO:0045109 11 7 0,000 0,02024659 0,05902049 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,02024659 0,05894578 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,02024659 0,05887126 ! fibrinolysis GO:0042730 9 7 0,000 0,02024659 0,05879693 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,02024659 0,05872278 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,02024659 0,05864882 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,02024659 0,05857505 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,02024659 0,05850146 ! response to tropane GO:0014073 13 7 0,000 0,02024659 0,05842806 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,02024659 0,05835484 ! melanosome localization GO:0032400 10 7 0,000 0,02024659 0,05828181 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,02024659 0,05820896 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,02024659 0,05813629 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,02024659 0,0580638 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,02024659 0,05799149 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,02024659 0,05791936 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,02024659 0,05784741 ! mast cell activation GO:0045576 9 7 0,000 0,02024659 0,05777564 ! multicellular organismal aging GO:0010259 11 7 0,000 0,02024659 0,05770405 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,02024659 0,05763263 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,02024659 0,05756139 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,02024659 0,05749033 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,02024659 0,05741944 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,02024659 0,05734873 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,02024659 0,05727819 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,02024659 0,05720782 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,02024659 0,05713763 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,02024659 0,0570676 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,02024659 0,05699775 ! regulation of lipid transport GO:0032368 13 7 0,000 0,02024659 0,05692807 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,02024659 0,05685857 ! neuroblast proliferation GO:0007405 13 7 0,000 0,02024659 0,05678923 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,02024659 0,05672005 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,02024659 0,05665105 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,02024659 0,05658222 ! diuresis GO:0030146 12 7 0,000 0,02024659 0,05651355 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,02024659 0,05644505 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,02024659 0,05637671 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02024659 0,05630854 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,02024659 0,05624054 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02024659 0,0561727 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02024659 0,05610502 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02024659 0,0560375 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,02024659 0,05597015 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,02024659 0,05590296 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,02024659 0,05583593 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,02024659 0,05576906 ! lymph node development GO:0048535 9 7 0,000 0,02024659 0,05570235 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,02024659 0,0556358 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02024659 0,05556941 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,02024659 0,05550318 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,02024659 0,0554371 ! ATP catabolic process GO:0006200 10 7 0,000 0,02024659 0,05537118 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,02024659 0,05530542 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,02024659 0,05523982 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,02024659 0,05517437 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,02024659 0,05510907 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,02024659 0,05504393 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,02024659 0,05497894 ! muscle adaptation GO:0043500 12 7 0,000 0,02024659 0,05491411 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,02024659 0,05484943 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,02024659 0,0547849 ! retina homeostasis GO:0001895 9 7 0,000 0,02024659 0,05472052 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,02024659 0,0546563 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,02024659 0,05459222 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,02024659 0,0545283 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,02024659 0,05446452 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,02024659 0,05440089 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,02024659 0,05433742 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02024659 0,05427409 ! regulation of adenylate cyclase activity GO:0045761 131 77 1,000 0,02124066 0,05687254 ! gland development GO:0048732 148 77 1,000 0,02124066 0,05680641 ! regulation of cyclase activity GO:0031279 132 78 1,000 0,02175948 0,05812637 ! regulation of cAMP biosynthetic process GO:0030817 136 79 1,000 0,02228356 0,0594573 ! regulation of lyase activity GO:0051339 133 79 1,000 0,02228356 0,05938841 ! protein localization in nucleus GO:0034504 133 80 1,000 0,02281287 0,06072871 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,02310596 0,06143781 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,02310596 0,06136687 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,02310596 0,06129609 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,02310596 0,06122547 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,02310596 0,06115501 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,02310596 0,06108472 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,02310596 0,06101459 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,02310596 0,06094462 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,02310596 0,06087481 ! phosphate transport GO:0006817 10 8 0,000 0,02310596 0,06080516 ! N-glycan processing GO:0006491 12 8 0,000 0,02310596 0,06073567 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,02310596 0,06066633 ! UTP metabolic process GO:0046051 8 8 0,000 0,02310596 0,06059716 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,02310596 0,06052814 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,02310596 0,06045928 GO:0046457|prostanoid biosynthetic process, ! induction of positive chemotaxis GO:0050930 14 8 0,000 0,02310596 0,06039058 ! neurotransmitter uptake GO:0001504 10 8 0,000 0,02310596 0,06032203 ! succinate metabolic process GO:0006105 14 8 0,000 0,02310596 0,06025364 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,02310596 0,0601854 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02310596 0,06011732 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,02310596 0,06004939 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,02310596 0,05998161 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,02310596 0,05991399 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,02310596 0,05984652 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02310596 0,0597792 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,02310596 0,05971203 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,02310596 0,05964501 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,02310596 0,05957815 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,02310596 0,05951143 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,02310596 0,05944486 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,02310596 0,05937844 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,02310596 0,05931217 ! astrocyte differentiation GO:0048708 16 8 0,000 0,02310596 0,05924605 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,02310596 0,05918007 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,02310596 0,05911425 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,02310596 0,05904856 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,02310596 0,05898303 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,02310596 0,05891764 ! melanin metabolic process GO:0006582 12 8 0,000 0,02310596 0,05885239 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,02310596 0,05878729 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02310596 0,05872233 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,02310596 0,05865751 ! macrophage activation GO:0042116 12 8 0,000 0,02310596 0,05859284 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,02310596 0,05852831 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,02310596 0,05846392 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,02310596 0,05839968 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,02310596 0,05833557 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02310596 0,05827161 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,02310596 0,05820778 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,02310596 0,0581441 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,02310596 0,05808055 ! ruffle organization GO:0031529 11 8 0,000 0,02310596 0,05801715 ! osteoblast development GO:0002076 13 8 0,000 0,02310596 0,05795388 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,02310596 0,05789075 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,02310596 0,05782776 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,02310596 0,0577649 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,02310596 0,05770218 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,02310596 0,0576396 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,02310596 0,05757715 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,02310596 0,05751483 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,02310596 0,05745266 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,02310596 0,05739061 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,02310596 0,0573287 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,02310596 0,05726693 ! oligodendrocyte development GO:0014003 8 8 0,000 0,02310596 0,05720528 ! segment specification GO:0007379 10 8 0,000 0,02310596 0,05714377 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,02310596 0,05708239 ! cellular extravasation GO:0045123 11 8 0,000 0,02310596 0,05702114 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,02310596 0,05696003 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,02310596 0,05689904 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,02310596 0,05683819 ! snRNA metabolic process GO:0016073 10 8 0,000 0,02310596 0,05677746 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,02310596 0,05671687 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,02310596 0,0566564 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,02310596 0,05659607 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,02310596 0,05653586 ! nucleosome disassembly GO:0006337 12 8 0,000 0,02310596 0,05647578 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,02310596 0,05641582 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,02310596 0,056356 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,02310596 0,0562963 ! icosanoid secretion GO:0032309 12 8 0,000 0,02310596 0,05623673 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,02310596 0,05617728 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02310596 0,05611796 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,02310596 0,05605876 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,02310596 0,05599969 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,02310596 0,05594074 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,02310596 0,05588192 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,02310596 0,05582322 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,02310596 0,05576465 ! sterol catabolic process GO:0016127 9 8 0,000 0,02310596 0,05570619 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,02310596 0,05564786 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,02310596 0,05558965 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,02310596 0,05553156 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,02310596 0,0554736 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02310596 0,05541575 ! prophase GO:0051324 11 8 0,000 0,02310596 0,05535803 ! S phase GO:0051320 8 8 0,000 0,02310596 0,05530042 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,02310596 0,05524294 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,02310596 0,05518557 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,02310596 0,05512833 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,02310596 0,0550712 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,02310596 0,05501419 ! hormone catabolic process GO:0042447 13 8 0,000 0,02310596 0,0549573 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,02310596 0,05490052 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,02310596 0,05484387 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,02310596 0,05478733 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,02310596 0,0547309 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,02310596 0,0546746 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,02310596 0,0546184 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,02310596 0,05456233 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02310596 0,05450637 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,02310596 0,05445052 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,02310596 0,05439479 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,02310596 0,05433917 ! lamellipodium assembly GO:0030032 9 8 0,000 0,02310596 0,05428366 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02310596 0,05422827 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,02310596 0,05417299 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,02310596 0,05411783 ! regulation of cAMP metabolic process GO:0030814 141 81 1,000 0,02334737 0,05462762 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,02334737 0,0545721 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 1,000 0,02388702 0,05577681 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 1,000 0,02388702 0,05572024 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 1,000 0,0244318 0,05693328 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 0,02498167 0,05815572 ! regulation of membrane potential GO:0042391 128 85 1,000 0,0255366 0,05938744 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,02595714 0,06030448 ! telencephalon cell migration GO:0022029 16 9 0,000 0,02595714 0,06024362 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,02595714 0,06018289 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,02595714 0,06012229 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,02595714 0,0600618 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,02595714 0,06000144 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02595714 0,0599412 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,02595714 0,05988107 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,02595714 0,05982107 ! GTP metabolic process GO:0046039 9 9 0,000 0,02595714 0,05976119 ! elastic fiber assembly GO:0048251 13 9 0,000 0,02595714 0,05970143 ! social behavior GO:0035176 14 9 0,000 0,02595714 0,05964179 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,02595714 0,05958227 ! artery development GO:0060840 19 9 0,000 0,02595714 0,05952286 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,02595714 0,05946358 ! response to pain GO:0048265 16 9 0,000 0,02595714 0,05940441 ! protein complex disassembly GO:0043241 17 9 0,000 0,02595714 0,05934536 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,02595714 0,05928643 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,02595714 0,05922761 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,02595714 0,05916891 ! lung alveolus development GO:0048286 17 9 0,000 0,02595714 0,05911033 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,02595714 0,05905186 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,02595714 0,05899351 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,02595714 0,05893527 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,02595714 0,05887715 ! ventral spinal cord development GO:0021517 11 9 0,000 0,02595714 0,05881914 ! protein targeting to ER GO:0045047 19 9 0,000 0,02595714 0,05876125 ! T cell selection GO:0045058 18 9 0,000 0,02595714 0,05870347 ! endoderm development GO:0007492 12 9 0,000 0,02595714 0,05864581 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,02595714 0,05858825 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,02595714 0,05853081 ! arginine catabolic process GO:0006527 10 9 0,000 0,02595714 0,05847349 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,02595714 0,05841627 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,02595714 0,05835917 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,02595714 0,05830218 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02595714 0,0582453 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,02595714 0,05818853 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,02595714 0,05813187 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,02595714 0,05807532 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,02595714 0,05801888 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02595714 0,05796255 ! mannose metabolic process GO:0006013 9 9 0,000 0,02595714 0,05790633 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,02595714 0,05785022 ! epithelial cell development GO:0002064 10 9 0,000 0,02595714 0,05779422 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,02595714 0,05773833 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,02595714 0,05768254 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,02595714 0,05762686 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,02595714 0,05757129 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,02595714 0,05751583 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,02595714 0,05746047 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,02595714 0,05740522 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,02595714 0,05735008 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,02595714 0,05729504 ! blastoderm segmentation GO:0007350 11 9 0,000 0,02595714 0,05724011 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,02595714 0,05718528 ! DNA ligation GO:0006266 14 9 0,000 0,02595714 0,05713056 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,02595714 0,05707594 ! response to amine stimulus GO:0014075 13 9 0,000 0,02595714 0,05702142 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,02595714 0,05696701 ! erythrocyte development GO:0048821 11 9 0,000 0,02595714 0,05691271 ! renal water homeostasis GO:0003091 14 9 0,000 0,02595714 0,05685851 ! postreplication repair GO:0006301 11 9 0,000 0,02595714 0,05680441 ! mRNA cleavage GO:0006379 13 9 0,000 0,02595714 0,05675041 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,02595714 0,05669652 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,02595714 0,05664272 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,02595714 0,05658903 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,02595714 0,05653545 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,02595714 0,05648196 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,02595714 0,05642857 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,02595714 0,05637529 ! acid secretion GO:0046717 14 9 0,000 0,02595714 0,0563221 ! musculoskeletal movement GO:0050881 11 9 0,000 0,02595714 0,05626902 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,02595714 0,05621604 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,02595714 0,05616315 ! purine base metabolic process GO:0006144 18 9 0,000 0,02595714 0,05611037 ! oocyte differentiation GO:0009994 12 9 0,000 0,02595714 0,05605768 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,02595714 0,05600509 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,02595714 0,05595261 ! spleen development GO:0048536 15 9 0,000 0,02595714 0,05590022 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,02595714 0,05584792 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,02595714 0,05579573 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,02595714 0,05574363 ! blastocyst formation GO:0001825 12 9 0,000 0,02595714 0,05569163 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,02595714 0,05563973 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,02595714 0,05558792 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,02595714 0,05553622 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,02595714 0,0554846 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02595714 0,05543308 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,02595714 0,05538166 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,02595714 0,05533033 ! prepulse inhibition GO:0060134 14 9 0,000 0,02595714 0,0552791 ! embryonic placenta development GO:0001892 12 9 0,000 0,02595714 0,05522797 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,02595714 0,05517692 ! insulin secretion GO:0030073 17 9 0,000 0,02595714 0,05512598 ! sequestering of metal ion GO:0051238 11 9 0,000 0,02595714 0,05507512 ! response to nicotine GO:0035094 16 9 0,000 0,02595714 0,05502436 ! establishment of cell polarity GO:0030010 12 9 0,000 0,02595714 0,05497369 ! nucleus localization GO:0051647 15 9 0,000 0,02595714 0,05492312 ! regulation of synapse organization GO:0050807 12 9 0,000 0,02595714 0,05487264 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 1,000 0,02609655 0,05511669 ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,0266615 0,0562582 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,02780623 0,05861992 ! reproductive developmental process GO:0003006 127 89 1,000 0,02780623 0,05856623 ! regulation of nucleotide metabolic process GO:0006140 150 89 1,000 0,02780623 0,05851265 ! regulation of T cell activation GO:0050863 128 89 1,000 0,02780623 0,05845917 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,02880017 0,06049351 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,02880017 0,06043831 ! neuron fate specification GO:0048665 11 10 0,000 0,02880017 0,06038322 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,02880017 0,06032822 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,02880017 0,06027333 ! thyroid gland development GO:0030878 19 10 0,000 0,02880017 0,06021854 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,02880017 0,06016384 ! synapsis GO:0007129 13 10 0,000 0,02880017 0,06010925 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,02880017 0,06005475 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,02880017 0,06000035 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,02880017 0,05994605 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,02880017 0,05989185 ! sulfate transport GO:0008272 12 10 0,000 0,02880017 0,05983775 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,02880017 0,05978375 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,02880017 0,05972984 ! androgen metabolic process GO:0008209 13 10 0,000 0,02880017 0,05967603 ! phospholipid efflux GO:0033700 16 10 0,000 0,02880017 0,05962231 ! hippocampus development GO:0021766 19 10 0,000 0,02880017 0,0595687 ! blood vessel remodeling GO:0001974 21 10 0,000 0,02880017 0,05951518 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,02880017 0,05946175 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,02880017 0,05940842 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,02880017 0,05935519 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,02880017 0,05930205 ! pathogenesis GO:0009405 13 10 0,000 0,02880017 0,05924901 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,02880017 0,05919606 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02880017 0,05914321 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,02880017 0,05909045 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,02880017 0,05903778 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,02880017 0,05898521 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,02880017 0,05893273 ! melanocyte differentiation GO:0030318 15 10 0,000 0,02880017 0,05888035 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,02880017 0,05882806 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,02880017 0,05877586 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02880017 0,05872375 ! B cell proliferation GO:0042100 14 10 0,000 0,02880017 0,05867174 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,02880017 0,05861981 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,02880017 0,05856798 ! forebrain cell migration GO:0021885 17 10 0,000 0,02880017 0,05851625 ! lipid digestion GO:0044241 15 10 0,000 0,02880017 0,0584646 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,02880017 0,05841304 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,02880017 0,05836158 ! UV protection GO:0009650 14 10 0,000 0,02880017 0,0583102 ! entry into host cell GO:0030260 20 10 0,000 0,02880017 0,05825892 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,02880017 0,05820772 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,02880017 0,05815662 ! negative regulation of ossification GO:0030279 19 10 0,000 0,02880017 0,05810561 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,02880017 0,05805468 ! regulation of bone resorption GO:0045124 24 10 0,000 0,02880017 0,05800384 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,02880017 0,0579531 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,02880017 0,05790244 ! regulation of organ growth GO:0046620 11 10 0,000 0,02880017 0,05785187 ! response to dsRNA GO:0043331 18 10 0,000 0,02880017 0,05780139 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,02880017 0,05775099 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02880017 0,05770069 ! embryonic axis specification GO:0000578 12 10 0,000 0,02880017 0,05765047 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,02880017 0,05760034 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,02880017 0,0575503 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,02880017 0,05750034 ! fucose catabolic process GO:0019317 16 10 0,000 0,02880017 0,05745047 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,02880017 0,05740068 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,02880017 0,05735099 ! protein sumoylation GO:0016925 12 10 0,000 0,02880017 0,05730138 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,02880017 0,05725185 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02880017 0,05720241 ! zymogen activation GO:0031638 14 10 0,000 0,02880017 0,05715305 ! salivary gland development GO:0007431 22 10 0,000 0,02880017 0,05710378 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02880017 0,0570546 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,02880017 0,0570055 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,02880017 0,05695648 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,02880017 0,05690755 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,02880017 0,0568587 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,02880017 0,05680994 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02880017 0,05676126 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,02880017 0,05671266 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,02880017 0,05666415 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,02880017 0,05661572 ! detection of bacterium GO:0016045 10 10 0,000 0,02880017 0,05656737 ! embryonic gut development GO:0048566 11 10 0,000 0,02880017 0,0565191 ! activation of innate immune response GO:0002218 10 10 0,000 0,02880017 0,05647092 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,02880017 0,05642282 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,02880017 0,0563748 ! developmental induction GO:0031128 13 10 0,000 0,02880017 0,05632686 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,02880017 0,05627901 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,02880017 0,05623123 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,02880017 0,05618354 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 1,000 0,02955996 0,05761686 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,02955996 0,05756808 ! angiogenesis GO:0001525 149 95 1,000 0,03135687 0,0610159 ! rRNA transcription GO:0009303 17 11 0,000 0,03163506 0,06150519 ! respiratory burst GO:0045730 14 11 0,000 0,03163506 0,06145324 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,03163506 0,06140138 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,03163506 0,06134961 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,03163506 0,06129792 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,03163506 0,06124633 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,03163506 0,06119482 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,03163506 0,06114339 ! RNA polyadenylation GO:0043631 19 11 0,000 0,03163506 0,06109205 ! regulation of positive chemotaxis GO:0050926 17 11 0,000 0,03163506 0,0610408 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,03163506 0,06098964 ! mating GO:0007618 14 11 0,000 0,03163506 0,06093856 ! T cell proliferation GO:0042098 20 11 0,000 0,03163506 0,06088756 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,03163506 0,06083665 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,03163506 0,06078583 ! bone resorption GO:0045453 16 11 0,000 0,03163506 0,06073509 ! regulated secretory pathway GO:0045055 14 11 0,000 0,03163506 0,06068443 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,03163506 0,06063386 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,03163506 0,06058338 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,03163506 0,06053298 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,03163506 0,06048266 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,03163506 0,06043242 ! syncytium formation GO:0006949 15 11 0,000 0,03163506 0,06038227 ! plasma membrane organization GO:0007009 18 11 0,000 0,03163506 0,0603322 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,03163506 0,06028222 ! focal adhesion formation GO:0048041 24 11 0,000 0,03163506 0,06023231 ! mitotic spindle organization GO:0007052 15 11 0,000 0,03163506 0,06018249 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,03163506 0,06013276 ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,03163506 0,0600831 ! adult heart development GO:0007512 11 11 0,000 0,03163506 0,06003353 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,03163506 0,05998404 ! temperature homeostasis GO:0001659 16 11 0,000 0,03163506 0,05993463 ! L-glutamate transport GO:0015813 16 11 0,000 0,03163506 0,0598853 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,03163506 0,05983605 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,03163506 0,05978688 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,03163506 0,0597378 ! stem cell development GO:0048864 29 11 0,000 0,03163506 0,05968879 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,03163506 0,05963987 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,03163506 0,05959102 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,03163506 0,05954226 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,03163506 0,05949357 ! vasoconstriction GO:0042310 15 11 0,000 0,03163506 0,05944496 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,03163506 0,05939644 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,03163506 0,05934799 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,03163506 0,05929962 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,03163506 0,05925133 ! ribosome assembly GO:0042255 13 11 0,000 0,03163506 0,05920312 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,03163506 0,05915499 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,03163506 0,05910693 ! chromatin silencing GO:0006342 19 11 0,000 0,03163506 0,05905896 ! nucleosome positioning GO:0016584 13 11 0,000 0,03163506 0,05901106 ! T cell homeostasis GO:0043029 20 11 0,000 0,03163506 0,05896324 ! regulation of isotype switching GO:0045191 19 11 0,000 0,03163506 0,05891549 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,03163506 0,05886783 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,03163506 0,05882024 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,03163506 0,05877273 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,03163506 0,05872529 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,03163506 0,05867793 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,03163506 0,05863065 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,03163506 0,05858344 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,03163506 0,05853631 ! male genitalia development GO:0030539 13 11 0,000 0,03163506 0,05848926 ! cholesterol efflux GO:0033344 19 11 0,000 0,03163506 0,05844228 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,03163506 0,05839537 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,03163506 0,05834855 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,03163506 0,05830179 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,03163506 0,05825511 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,03163506 0,05820851 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,03163506 0,05816198 ! defense response to fungus GO:0050832 12 11 0,000 0,03163506 0,05811552 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,03163506 0,05806914 ! lysogeny GO:0030069 18 11 0,000 0,03163506 0,05802284 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,03163506 0,0579766 ! acrosome reaction GO:0007340 13 11 0,000 0,03163506 0,05793044 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,03163506 0,05788436 ! in utero embryonic development GO:0001701 147 96 1,000 0,03196529 0,0584421 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 1,000 0,03257838 0,0595157 ! extracellular structure organization GO:0043062 156 99 1,000 0,03381844 0,06173208 ! protein import GO:0017038 156 99 1,000 0,03381844 0,06168313 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,03444536 0,06277681 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 1,000 0,03444536 0,06272711 ! protein localization in organelle GO:0033365 161 100 1,000 0,03444536 0,06267748 ! lactation GO:0007595 20 12 0,000 0,03446184 0,06265788 ! reproductive cellular process GO:0048610 14 12 0,000 0,03446184 0,06260839 ! tRNA modification GO:0006400 14 12 0,000 0,03446184 0,06255898 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,03446184 0,06250964 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,03446184 0,06246038 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,03446184 0,0624112 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,03446184 0,06236209 ! non-recombinational repair GO:0000726 19 12 0,000 0,03446184 0,06231307 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,03446184 0,06226412 ! peroxisomal transport GO:0043574 21 12 0,000 0,03446184 0,06221524 ! cartilage condensation GO:0001502 18 12 0,000 0,03446184 0,06216645 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,03446184 0,06211773 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,03446184 0,06206909 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,03446184 0,06202052 ! heart looping GO:0001947 15 12 0,000 0,03446184 0,06197203 ! palate development GO:0060021 15 12 0,000 0,03446184 0,06192361 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,03446184 0,06187527 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,03446184 0,06182701 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,03446184 0,06177882 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,03446184 0,0617307 ! arginine metabolic process GO:0006525 13 12 0,000 0,03446184 0,06168266 ! methionine metabolic process GO:0006555 13 12 0,000 0,03446184 0,0616347 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,03446184 0,06158681 ! Golgi organization GO:0007030 18 12 0,000 0,03446184 0,06153899 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,03446184 0,06149125 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,03446184 0,06144358 ! monoamine transport GO:0015844 13 12 0,000 0,03446184 0,06139599 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03446184 0,06134847 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,03446184 0,06130102 ! L-amino acid transport GO:0015807 20 12 0,000 0,03446184 0,06125365 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,03446184 0,06120635 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,03446184 0,06115912 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,03446184 0,06111197 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03446184 0,06106489 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,03446184 0,06101788 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,03446184 0,06097094 ! cerebellum development GO:0021549 13 12 0,000 0,03446184 0,06092408 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,03446184 0,06087728 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,03446184 0,06083056 ! histone methylation GO:0016571 15 12 0,000 0,03446184 0,06078391 ! gland morphogenesis GO:0022612 23 12 0,000 0,03446184 0,06073733 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,03446184 0,06069083 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,03446184 0,06064439 ! regulation of epidermis development GO:0045682 17 12 0,000 0,03446184 0,06059803 ! intestinal absorption GO:0050892 19 12 0,000 0,03446184 0,06055174 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,03446184 0,06050551 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,03446184 0,06045936 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,03446184 0,06041328 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,03446184 0,06036727 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,03446184 0,06032133 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,03446184 0,06027545 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,03446184 0,06022965 ! microspike assembly GO:0030035 23 12 0,000 0,03446184 0,06018392 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,03446184 0,06013826 ! response to cold GO:0009409 14 12 0,000 0,03446184 0,06009266 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,03728052 0,06495848 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,03728052 0,06490931 ! cGMP metabolic process GO:0046068 16 13 0,000 0,03728052 0,06486021 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,03728052 0,06481119 ! water transport GO:0006833 17 13 0,000 0,03728052 0,06476224 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,03728052 0,06471336 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,03728052 0,06466456 ! lipid localization GO:0010876 24 13 0,000 0,03728052 0,06461583 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,03728052 0,06456717 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,03728052 0,06451859 ! organelle fusion GO:0048284 28 13 0,000 0,03728052 0,06447008 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,03728052 0,06442164 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,03728052 0,06437327 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,03728052 0,06432498 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,03728052 0,06427676 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,03728052 0,06422861 ! response to hexose stimulus GO:0009746 19 13 0,000 0,03728052 0,06418054 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,03728052 0,06413254 ! glutamate metabolic process GO:0006536 18 13 0,000 0,03728052 0,0640846 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,03728052 0,06403674 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,03728052 0,06398896 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,03728052 0,06394124 ! NAD metabolic process GO:0019674 21 13 0,000 0,03728052 0,06389359 ! exocrine system development GO:0035272 27 13 0,000 0,03728052 0,06384602 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,03728052 0,06379851 ! bone mineralization GO:0030282 15 13 0,000 0,03728052 0,06375108 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,03728052 0,06370371 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,03728052 0,06365642 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,03728052 0,0636092 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,03728052 0,06356205 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,03728052 0,06351496 ! genitalia development GO:0048806 15 13 0,000 0,03728052 0,06346795 ! cellular pigmentation GO:0033059 24 13 0,000 0,03728052 0,06342101 ! tissue regeneration GO:0042246 21 13 0,000 0,03728052 0,06337413 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,03728052 0,06332733 ! cofactor transport GO:0051181 19 13 0,000 0,03728052 0,06328059 ! NADP metabolic process GO:0006739 18 13 0,000 0,03728052 0,06323392 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,03728052 0,06318733 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,03728052 0,0631408 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03728052 0,06309433 ! gas transport GO:0015669 18 13 0,000 0,03728052 0,06304794 ! regulation of RNA stability GO:0043487 28 13 0,000 0,03728052 0,06300162 ! heme biosynthetic process GO:0006783 20 13 0,000 0,03728052 0,06295536 ! regulation of axon extension GO:0030516 23 13 0,000 0,03728052 0,06290917 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,03728052 0,06286305 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,03728052 0,062817 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,03728052 0,06277101 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,03728052 0,06272509 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,03728052 0,06267924 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,04009114 0,06735546 ! superoxide anion generation GO:0042554 18 14 0,000 0,04009114 0,06730629 ! neuron maturation GO:0042551 21 14 0,000 0,04009114 0,0672572 ! regulation of S phase GO:0033261 18 14 0,000 0,04009114 0,06720818 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,04009114 0,06715923 ! myotube differentiation GO:0014902 21 14 0,000 0,04009114 0,06711035 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,04009114 0,06706154 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,04009114 0,06701281 ! inositol metabolic process GO:0006020 20 14 0,000 0,04009114 0,06696414 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,04009114 0,06691555 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,04009114 0,06686702 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,04009114 0,06681857 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,04009114 0,06677018 ! gene silencing by RNA GO:0031047 20 14 0,000 0,04009114 0,06672187 ! response to cAMP GO:0051591 19 14 0,000 0,04009114 0,06667362 ! limbic system development GO:0021761 25 14 0,000 0,04009114 0,06662545 ! startle response GO:0001964 21 14 0,000 0,04009114 0,06657734 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,04009114 0,06652931 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,04009114 0,06648134 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,04009114 0,06643345 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,04009114 0,06638562 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,04009114 0,06633786 ! glycine metabolic process GO:0006544 22 14 0,000 0,04009114 0,06629017 ! pituitary gland development GO:0021983 23 14 0,000 0,04009114 0,06624254 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,04009114 0,06619499 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,04009114 0,06614751 ! regulation of heart rate GO:0002027 23 14 0,000 0,04009114 0,06610009 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,04009114 0,06605274 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,04009114 0,06600546 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,04009114 0,06595824 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,04009114 0,0659111 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,04009114 0,06586402 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,04009114 0,065817 ! axon cargo transport GO:0008088 27 14 0,000 0,04009114 0,06577006 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,04009114 0,06572318 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,04009114 0,06567637 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,04009114 0,06562962 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,04009114 0,06558295 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04009114 0,06553633 ! mRNA splice site selection GO:0006376 26 14 0,000 0,04009114 0,06548979 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,04009114 0,06544331 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,04009114 0,0653969 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,04009114 0,06535055 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,04009114 0,06530427 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,04009114 0,06525805 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,04009114 0,0652119 ! muscle maintenance GO:0046716 19 14 0,000 0,04009114 0,06516581 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,04009114 0,06511979 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,04009114 0,06507383 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,04009114 0,06502794 ! cell killing GO:0001906 20 14 0,000 0,04009114 0,06498212 ! cilium assembly GO:0042384 20 14 0,000 0,04009114 0,06493635 ! peptide hormone secretion GO:0030072 23 14 0,000 0,04009114 0,06489066 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,04289371 0,06937802 ! positive regulation of cell size GO:0045793 20 15 0,000 0,04289371 0,06932926 ! metencephalon development GO:0022037 19 15 0,000 0,04289371 0,06928058 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,04289371 0,06923196 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,04289371 0,06918341 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,04289371 0,06913493 ! skin development GO:0043588 25 15 0,000 0,04289371 0,06908651 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,04289371 0,06903817 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,04289371 0,06898989 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,04289371 0,06894168 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,04289371 0,06889353 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,04289371 0,06884546 ! bile acid metabolic process GO:0008206 22 15 0,000 0,04289371 0,06879745 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,04289371 0,06874951 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,04289371 0,06870163 ! adult walking behavior GO:0007628 25 15 0,000 0,04289371 0,06865382 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,04289371 0,06860608 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,04289371 0,0685584 ! myoblast differentiation GO:0045445 27 15 0,000 0,04289371 0,06851079 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,04289371 0,06846325 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,04289371 0,06841577 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,04289371 0,06836836 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,04289371 0,06832101 ! cerebral cortex development GO:0021987 29 15 0,000 0,04289371 0,06827373 ! response to osmotic stress GO:0006970 22 15 0,000 0,04289371 0,06822652 ! vesicle coating GO:0006901 25 15 0,000 0,04289371 0,06817937 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,04289371 0,06813228 ! DNA integration GO:0015074 22 15 0,000 0,04289371 0,06808526 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,04289371 0,0680383 ! peptide secretion GO:0002790 27 15 0,000 0,04289371 0,06799141 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,04289371 0,06794459 ! regulation of vasodilation GO:0042312 24 15 0,000 0,04289371 0,06789783 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,04289371 0,06785113 ! neuron recognition GO:0008038 22 15 0,000 0,04289371 0,0678045 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,04289371 0,06775793 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,04289371 0,06771142 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,04289371 0,06766498 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,04289371 0,0676186 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,04289371 0,06757229 ! biomineral formation GO:0031214 18 15 0,000 0,04289371 0,06752604 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,04289371 0,06747985 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,04289371 0,06743373 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,04289371 0,06738766 ! dopamine metabolic process GO:0042417 30 15 0,000 0,04289371 0,06734167 ! organic cation transport GO:0015695 19 15 0,000 0,04289371 0,06729573 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,04289371 0,06724986 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,04289371 0,06720405 ! defense response to virus GO:0051607 27 15 0,000 0,04289371 0,0671583 ! peptide hormone processing GO:0016486 19 15 0,000 0,04289371 0,06711261 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,04289371 0,06706699 ! protein secretion GO:0009306 27 16 0,000 0,04568826 0,07138791 ! hormone secretion GO:0046879 25 16 0,000 0,04568826 0,07133945 ! bone remodeling GO:0046849 24 16 0,000 0,04568826 0,07129105 ! endothelial cell migration GO:0043542 22 16 0,000 0,04568826 0,07124272 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,04568826 0,07119445 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,04568826 0,07114625 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,04568826 0,07109811 ! glial cell development GO:0021782 24 16 0,000 0,04568826 0,07105004 ! patterning of blood vessels GO:0001569 24 16 0,000 0,04568826 0,07100203 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,04568826 0,07095409 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,04568826 0,07090621 ! protein polyubiquitination GO:0000209 26 16 0,000 0,04568826 0,0708584 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,04568826 0,07081065 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,04568826 0,07076297 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,04568826 0,07071535 ! fructose metabolic process GO:0006000 20 16 0,000 0,04568826 0,07066779 ! regulation of protein binding GO:0043393 27 16 0,000 0,04568826 0,0706203 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,04568826 0,07057287 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,04568826 0,07052551 ! protein export from nucleus GO:0006611 24 16 0,000 0,04568826 0,07047821 ! negative regulation of immune response GO:0050777 28 16 0,000 0,04568826 0,07043097 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,04568826 0,0703838 ! DNA replication initiation GO:0006270 25 16 0,000 0,04568826 0,07033669 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,04568826 0,07028964 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,04568826 0,07024265 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,04568826 0,07019573 ! diencephalon development GO:0021536 25 16 0,000 0,04568826 0,07014887 ! oogenesis GO:0048477 23 16 0,000 0,04568826 0,07010207 ! neural crest cell migration GO:0001755 24 16 0,000 0,04568826 0,07005534 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,04568826 0,07000867 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,04568826 0,06996206 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,04568826 0,06991551 ! steroid catabolic process GO:0006706 22 16 0,000 0,04568826 0,06986902 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,04568826 0,0698226 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,04568826 0,06977623 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,04568826 0,06972993 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,04568826 0,06968369 ! sperm-egg recognition GO:0035036 16 16 0,000 0,04568826 0,06963751 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,04568826 0,0695914 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,04568826 0,06954534 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,04568826 0,06949934 ! negative regulation of translation GO:0017148 22 16 0,000 0,04568826 0,06945341 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,04847482 0,07364074 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,04847482 0,07359213 ! negative regulation of defense response GO:0031348 19 17 0,000 0,04847482 0,07354359 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,04847482 0,07349511 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,04847482 0,07344669 ! glycerol metabolic process GO:0006071 20 17 0,000 0,04847482 0,07339834 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,04847482 0,07335005 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,04847482 0,07330182 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,04847482 0,07325366 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,04847482 0,07320556 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,04847482 0,07315753 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,04847482 0,07310956 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,04847482 0,07306165 ! memory GO:0007613 25 17 0,000 0,04847482 0,0730138 ! keratinization GO:0031424 17 17 0,000 0,04847482 0,07296602 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,04847482 0,0729183 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,04847482 0,07287064 ! retinoid metabolic process GO:0001523 22 17 0,000 0,04847482 0,07282304 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,04847482 0,07277551 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,04847482 0,07272803 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,04847482 0,07268062 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,04847482 0,07263327 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,04847482 0,07258599 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,04847482 0,07253876 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,04847482 0,0724916 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,04847482 0,07244449 ! membrane budding GO:0006900 29 17 0,000 0,04847482 0,07239745 ! heme metabolic process GO:0042168 27 17 0,000 0,04847482 0,07235047 ! actin filament bundle formation GO:0051017 26 17 0,000 0,04847482 0,07230355 ! body fluid secretion GO:0007589 27 17 0,000 0,04847482 0,07225669 ! stem cell differentiation GO:0048863 36 17 0,000 0,04847482 0,07220989 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,04847482 0,07216316 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,04847482 0,07211648 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,04847482 0,07206986 ! sensory perception of pain GO:0019233 23 17 0,000 0,04847482 0,0720233 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,04847482 0,07197681 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,04847482 0,07193037 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,04847482 0,07188399 ! synaptogenesis GO:0007416 24 17 0,000 0,04847482 0,07183768 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,04847482 0,07179142 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,04847482 0,07174522 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,04847482 0,07169908 ! cell-cell junction organization GO:0045216 25 17 0,000 0,04847482 0,071653 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,04847482 0,07160698 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,04847482 0,07156102 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,04847482 0,07151512 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,04847482 0,07146928 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,04847482 0,07142349 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,04847482 0,07137777 ! positive regulation of translation GO:0045727 28 18 0,000 0,05125339 0,07542085 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,05125339 0,07537263 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,05125339 0,07532447 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,05125339 0,07527637 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,05125339 0,07522833 ! cAMP metabolic process GO:0046058 33 18 0,000 0,05125339 0,07518035 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,05125339 0,07513244 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,05125339 0,07508458 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,05125339 0,07503679 ! axis specification GO:0009798 26 18 0,000 0,05125339 0,07498905 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,05125339 0,07494138 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,05125339 0,07489377 ! pancreas development GO:0031016 26 18 0,000 0,05125339 0,07484622 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,05125339 0,07479873 ! glutamine metabolic process GO:0006541 23 18 0,000 0,05125339 0,0747513 ! response to retinoic acid GO:0032526 25 18 0,000 0,05125339 0,07470393 ! pigmentation during development GO:0048066 31 18 0,000 0,05125339 0,07465661 ! central nervous system neuron development GO:0021954 30 18 0,000 0,05125339 0,07460936 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,05125339 0,07456217 ! fucose metabolic process GO:0006004 26 18 0,000 0,05125339 0,07451504 ! response to fungus GO:0009620 19 18 0,000 0,05125339 0,07446797 ! peptide cross-linking GO:0018149 31 18 0,000 0,05125339 0,07442096 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,05125339 0,074374 ! heart process GO:0003015 27 18 0,000 0,05125339 0,07432711 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,05125339 0,07428027 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,05125339 0,0742335 ! visual learning GO:0008542 35 18 0,000 0,05125339 0,07418678 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,05125339 0,07414012 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,05125339 0,07409352 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,05125339 0,07404698 ! vitamin transport GO:0051180 24 18 0,000 0,05125339 0,0740005 ! hormone transport GO:0009914 27 18 0,000 0,05125339 0,07395407 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,05125339 0,07390771 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,05125339 0,0738614 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,05125339 0,07381515 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,05125339 0,07376896 ! cell-cell recognition GO:0009988 20 18 0,000 0,05125339 0,07372282 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,05125339 0,07367675 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,05125339 0,07363073 ! regulation of glucose import GO:0046324 21 18 0,000 0,05125339 0,07358477 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,05125339 0,07353886 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,05125339 0,07349301 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,05402401 0,07741758 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,05402401 0,07736938 ! positive regulation of ossification GO:0045778 30 19 0,000 0,05402401 0,07732123 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,05402401 0,07727314 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,05402401 0,07722512 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,05402401 0,07717715 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,05402401 0,07712925 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,05402401 0,0770814 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,05402401 0,07703361 ! regeneration GO:0031099 32 19 0,000 0,05402401 0,07698588 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,05402401 0,07693821 ! response to alkaloid GO:0043279 32 19 0,000 0,05402401 0,0768906 ! sensory perception of taste GO:0050909 23 19 0,000 0,05402401 0,07684305 ! smooth muscle contraction GO:0006939 36 19 0,000 0,05402401 0,07679556 ! peroxisome organization GO:0007031 29 19 0,000 0,05402401 0,07674813 ! digestive system process GO:0022600 30 19 0,000 0,05402401 0,07670075 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,05402401 0,07665343 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,05402401 0,07660618 ! response to vitamin A GO:0033189 26 19 0,000 0,05402401 0,07655897 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,05402401 0,07651183 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,05402401 0,07646475 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,05402401 0,07641772 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,05402401 0,07637075 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,05402401 0,07632384 ! plasma membrane fusion GO:0045026 23 19 0,000 0,05402401 0,07627699 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,05402401 0,07623019 ! cytolysis GO:0019835 20 19 0,000 0,05402401 0,07618346 ! renal system process GO:0003014 35 19 0,000 0,05402401 0,07613677 ! vasodilation GO:0042311 33 19 0,000 0,05402401 0,07609015 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,05402401 0,07604358 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,05402401 0,07599707 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,05402401 0,07595062 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,05402401 0,07590422 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,05402401 0,07585789 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,05402401 0,0758116 ! sarcomere organization GO:0045214 23 19 0,000 0,05402401 0,07576538 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,05402401 0,07571921 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,05402401 0,07567309 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,05402401 0,07562703 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,05402401 0,07558103 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,05402401 0,07553509 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,05402401 0,0754892 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,05402401 0,07544336 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,05402401 0,07539758 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,05678669 0,07920521 ! iron ion transport GO:0006826 37 20 0,000 0,05678669 0,07915721 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,05678669 0,07910926 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,05678669 0,07906138 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,05678669 0,07901355 ! response to vitamin GO:0033273 29 20 0,000 0,05678669 0,07896578 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,05678669 0,07891806 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,05678669 0,07887041 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,05678669 0,07882281 ! spinal cord development GO:0021510 31 20 0,000 0,05678669 0,07877527 ! response to ethanol GO:0045471 37 20 0,000 0,05678669 0,07872778 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,05678669 0,07868036 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,05678669 0,07863299 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,05678669 0,07858568 ! chromosome condensation GO:0030261 31 20 0,000 0,05678669 0,07853842 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,05678669 0,07849122 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,05678669 0,07844408 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,05678669 0,07839699 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,05678669 0,07834997 ! pallium development GO:0021543 38 20 0,000 0,05678669 0,07830299 ! DNA modification GO:0006304 28 20 0,000 0,05678669 0,07825608 ! positive regulation of locomotion GO:0040017 35 20 0,000 0,05678669 0,07820922 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 45 20 0,000 0,05678669 0,07816241 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,05678669 0,07811567 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,05678669 0,07806897 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,05678669 0,07802234 ! collagen catabolic process GO:0030574 25 20 0,000 0,05678669 0,07797576 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,05678669 0,07792923 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,05678669 0,07788276 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,05678669 0,07783635 ! alditol metabolic process GO:0019400 24 20 0,000 0,05678669 0,07778999 ! actin filament-based movement GO:0030048 34 20 0,000 0,05678669 0,07774369 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,05954147 0,08146661 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,05954147 0,08141818 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,05954147 0,0813698 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,05954147 0,08132148 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,05954147 0,08127322 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,05954147 0,08122501 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,05954147 0,08117687 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,05954147 0,08112878 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,05954147 0,08108074 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,05954147 0,08103277 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,05954147 0,08098485 ! regulation of chemotaxis GO:0050920 36 21 0,000 0,05954147 0,08093698 ! vesicle docking GO:0048278 27 21 0,000 0,05954147 0,08088918 ! phototransduction GO:0007602 25 21 0,000 0,05954147 0,08084143 ! dendrite development GO:0016358 35 21 0,000 0,05954147 0,08079373 ! visual behavior GO:0007632 39 21 0,000 0,05954147 0,08074609 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,05954147 0,08069851 ! ovarian follicle development GO:0001541 30 21 0,000 0,05954147 0,08065099 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,05954147 0,08060352 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,05954147 0,0805561 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,05954147 0,08050874 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,05954147 0,08046144 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,05954147 0,0804142 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,05954147 0,080367 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,05954147 0,08031987 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,05954147 0,08027279 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,05954147 0,08022576 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,05954147 0,08017879 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,05954147 0,08013188 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,05954147 0,08008501 ! fatty acid transport GO:0015908 30 21 0,000 0,05954147 0,08003821 ! immunoglobulin production GO:0002377 33 21 0,000 0,05954147 0,07999146 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,05954147 0,07994476 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,05954147 0,07989812 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,05954147 0,07985153 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,05954147 0,079805 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,05954147 0,07975852 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,05954147 0,07971209 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,05954147 0,07966572 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,05954147 0,0796194 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,05954147 0,07957314 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,05954147 0,07952693 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,05954147 0,07948077 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,05954147 0,07943467 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,05954147 0,07938862 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,05954147 0,07934263 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,06228835 0,08295496 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,06228835 0,08290695 ! viral genome replication GO:0019079 29 22 0,000 0,06228835 0,082859 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,06228835 0,08281111 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,06228835 0,08276327 ! leukocyte adhesion GO:0007159 38 22 0,000 0,06228835 0,08271548 ! molting cycle process GO:0022404 40 22 0,000 0,06228835 0,08266775 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,06228835 0,08262008 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,06228835 0,08257246 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,06228835 0,08252489 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,06228835 0,08247738 ! vasculogenesis GO:0001570 33 22 0,000 0,06228835 0,08242993 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,06228835 0,08238253 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,06228835 0,08233518 ! lysosome organization GO:0007040 37 22 0,000 0,06228835 0,08228789 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,06228835 0,08224065 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,06228835 0,08219347 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,06228835 0,08214634 ! regulation of behavior GO:0050795 38 22 0,000 0,06228835 0,08209926 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,06228835 0,08205224 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,06228835 0,08200527 ! membrane depolarization GO:0051899 35 22 0,000 0,06228835 0,08195836 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,06228835 0,0819115 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,06228835 0,08186469 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,06228835 0,08181794 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,06228835 0,08177124 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,06228835 0,08172459 ! blastocyst development GO:0001824 37 22 0,000 0,06228835 0,081678 ! neural tube closure GO:0001843 33 22 0,000 0,06228835 0,08163146 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,06228835 0,08158497 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,06502737 0,08512405 ! neuron fate commitment GO:0048663 32 23 0,000 0,06502737 0,08507563 ! embryonic pattern specification GO:0009880 31 23 0,000 0,06502737 0,08502727 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,06502737 0,08497895 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,06502737 0,0849307 ! vesicle targeting GO:0006903 32 23 0,000 0,06502737 0,0848825 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,06502737 0,08483435 ! osteoblast differentiation GO:0001649 40 23 0,000 0,06502737 0,08478626 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,06502737 0,08473822 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,06502737 0,08469024 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,06502737 0,08464231 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,06502737 0,08459443 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,06502737 0,08454661 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,06502737 0,08449885 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,06502737 0,08445114 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,06502737 0,08440348 ! pentose metabolic process GO:0019321 31 23 0,000 0,06502737 0,08435587 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,06502737 0,08430832 ! spermatid development GO:0007286 33 23 0,000 0,06502737 0,08426082 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,06502737 0,08421338 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,06502737 0,08416599 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,06502737 0,08411865 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,06502737 0,08407137 ! telomere organization GO:0032200 32 23 0,000 0,06502737 0,08402414 GO:0000723|telomere maintenance, ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,06502737 0,08397696 ! regulation of amine transport GO:0051952 38 23 0,000 0,06502737 0,08392983 ! liver development GO:0001889 40 23 0,000 0,06502737 0,08388276 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,06775855 0,08735688 ! initiation of viral infection GO:0019059 42 24 0,000 0,06775855 0,08730794 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,06775855 0,08725905 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,06775855 0,08721022 ! superoxide metabolic process GO:0006801 32 24 0,000 0,06775855 0,08716145 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,06775855 0,08711273 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,06775855 0,08706406 ! fat cell differentiation GO:0045444 37 24 0,000 0,06775855 0,08701545 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,06775855 0,08696689 ! sperm motility GO:0030317 27 24 0,000 0,06775855 0,08691839 ! vacuole organization GO:0007033 39 24 0,000 0,06775855 0,08686994 ! neural crest cell development GO:0014032 39 24 0,000 0,06775855 0,08682154 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,06775855 0,0867732 ! primary neural tube formation GO:0014020 35 24 0,000 0,06775855 0,08672491 ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,06775855 0,08667668 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,06775855 0,0866285 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,06775855 0,08658037 ! glutathione metabolic process GO:0006749 29 24 0,000 0,06775855 0,0865323 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,06775855 0,08648428 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,0704819 0,08991036 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,0704819 0,08986052 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,0704819 0,08981074 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,0704819 0,08976101 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,0704819 0,08971133 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,0704819 0,08966171 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,0704819 0,08961215 ! peptide transport GO:0015833 43 25 0,000 0,0704819 0,08956264 ! male gonad development GO:0008584 33 25 0,000 0,0704819 0,08951319 ! iron ion homeostasis GO:0055072 39 25 0,000 0,0704819 0,08946379 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,0704819 0,08941444 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,0704819 0,08936515 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,0704819 0,08931591 ! phospholipid transport GO:0015914 35 25 0,000 0,0704819 0,08926673 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,0704819 0,0892176 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,0704819 0,08916853 ! detection of light stimulus GO:0009583 30 25 0,000 0,0704819 0,08911951 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,0704819 0,08907054 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,0704819 0,08902163 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,07319746 0,09240074 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,07319746 0,09235006 ! translational initiation GO:0006413 43 26 0,000 0,07319746 0,09229943 ! circadian rhythm GO:0007623 42 26 0,000 0,07319746 0,09224885 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,07319746 0,09219833 ! post-embryonic development GO:0009791 42 26 0,000 0,07319746 0,09214787 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,07319746 0,09209746 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,07319746 0,0920471 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,07319746 0,09199681 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,07319746 0,09194656 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,07319746 0,09189637 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,07319746 0,09184624 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,07319746 0,09179616 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,07319746 0,09174613 ! regulation of coagulation GO:0050818 39 26 0,000 0,07319746 0,09169616 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,07590523 0,09503649 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,07590523 0,09498479 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,07590523 0,09493314 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,07590523 0,09488154 ! membrane docking GO:0022406 39 27 0,000 0,07590523 0,09483 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,07590523 0,09477852 ! catechol metabolic process GO:0009712 43 27 0,000 0,07590523 0,0947271 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,07590523 0,09467573 ! acute-phase response GO:0006953 42 27 0,000 0,07590523 0,09462441 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,07590523 0,09457315 ! myofibril assembly GO:0030239 36 27 0,000 0,07590523 0,09452195 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,07590523 0,0944708 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,07590523 0,09441971 ! natural killer cell activation GO:0030101 35 27 0,000 0,07590523 0,09436867 ! lipid oxidation GO:0034440 38 27 0,000 0,07590523 0,09431769 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,07590523 0,09426676 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,07590523 0,09421589 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,07590523 0,09416507 ! gene silencing GO:0016458 41 27 0,000 0,07590523 0,09411431 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,07860525 0,09740953 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,07860525 0,09735707 ! phenol metabolic process GO:0018958 44 28 0,000 0,07860525 0,09730467 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,07860525 0,09725233 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,07860525 0,09720004 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,07860525 0,09714781 ! cell junction assembly GO:0034329 56 28 0,000 0,07860525 0,09709564 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,07860525 0,09704352 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,07860525 0,09699146 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,07860525 0,09693945 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,07860525 0,0968875 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,07860525 0,09683561 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,07860525 0,09678377 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,07860525 0,09673199 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,07860525 0,09668026 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,07860525 0,09662858 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,07860525 0,09657697 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,07860525 0,0965254 ! mesoderm formation GO:0001707 46 28 0,000 0,07860525 0,0964739 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,07860525 0,09642244 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,07860525 0,09637105 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,07860525 0,0963197 ! BMP signaling pathway GO:0030509 40 28 0,000 0,07860525 0,09626841 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,07860525 0,09621718 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,07860525 0,096166 ! neural tube formation GO:0001841 41 28 0,000 0,07860525 0,09611488 ! placenta development GO:0001890 37 28 0,000 0,07860525 0,09606381 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,08129754 0,09930129 ! regulation of innate immune response GO:0045088 38 29 0,000 0,08129754 0,09924859 ! ovulation cycle process GO:0022602 41 29 0,000 0,08129754 0,09919593 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,08129754 0,09914334 ! protein targeting to membrane GO:0006612 53 29 0,000 0,08129754 0,0990908 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,08129754 0,09903831 ! mismatch repair GO:0006298 34 29 0,000 0,08129754 0,09898588 ! muscle cell development GO:0055001 38 29 0,000 0,08129754 0,09893351 ! formation of primary germ layer GO:0001704 48 29 0,000 0,08129754 0,09888119 ! telencephalon development GO:0021537 52 29 0,000 0,08129754 0,09882893 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,08129754 0,09877672 ! eye morphogenesis GO:0048592 51 29 0,000 0,08129754 0,09872457 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,08129754 0,09867247 ! tissue homeostasis GO:0001894 42 29 0,000 0,08129754 0,09862043 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,08398211 0,10182333 ! collagen metabolic process GO:0032963 40 30 0,000 0,08398211 0,10176968 ! organic anion transport GO:0015711 51 30 0,000 0,08398211 0,10171609 ! cholesterol transport GO:0030301 46 30 0,000 0,08398211 0,10166255 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 49 30 0,000 0,08398211 0,10160907 ! spindle organization GO:0007051 37 30 0,000 0,08398211 0,10155565 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,08398211 0,10150229 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,08398211 0,10144898 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,08398211 0,10139572 ! ceramide metabolic process GO:0006672 43 30 0,000 0,08398211 0,10134252 ! ovulation cycle GO:0042698 43 30 0,000 0,08398211 0,10128938 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,08398211 0,10123629 ! adult locomotory behavior GO:0008344 47 30 0,000 0,08398211 0,10118326 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,08398211 0,10113029 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,08398211 0,10107737 ! response to heat GO:0009408 41 30 0,000 0,08398211 0,1010245 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,08398211 0,10097169 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,08398211 0,10091894 ! negative regulation of secretion GO:0051048 49 31 0,000 0,08665899 0,10408129 ! glial cell differentiation GO:0010001 55 31 0,000 0,08665899 0,10402697 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,08665899 0,1039727 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,08665899 0,1039185 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,08665899 0,10386434 ! odontogenesis GO:0042476 50 31 0,000 0,08665899 0,10381025 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,08665899 0,10375621 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,08665899 0,10370222 ! metanephros development GO:0001656 58 31 0,000 0,08665899 0,1036483 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,08665899 0,10359443 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,08665899 0,10354061 ! cell fate specification GO:0001708 37 31 0,000 0,08665899 0,10348685 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,08665899 0,10343315 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,08665899 0,1033795 ! RNA modification GO:0009451 40 31 0,000 0,08665899 0,10332591 ! regulation of muscle development GO:0048634 48 32 0,000 0,0893282 0,10645329 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,0893282 0,10639817 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,0893282 0,10634309 ! meiosis I GO:0007127 52 32 0,000 0,0893282 0,10628808 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,0893282 0,10623312 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,0893282 0,10617822 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,0893282 0,10612338 GO:0006639|acylglycerol metabolic process, ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,0893282 0,10606859 ! cytokine production GO:0001816 44 32 0,000 0,0893282 0,10601386 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,0893282 0,10595918 ! vesicle localization GO:0051648 47 32 0,000 0,0893282 0,10590457 ! RNA export from nucleus GO:0006405 44 33 0,000 0,09198976 0,10900384 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,09198976 0,10894771 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,09198976 0,10889164 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,09198976 0,10883562 ! sister chromatid segregation GO:0000819 46 33 0,000 0,09198976 0,10877967 ! ear morphogenesis GO:0042471 42 33 0,000 0,09198976 0,10872377 ! actomyosin structure organization GO:0031032 43 33 0,000 0,09198976 0,10866793 ! cell junction organization GO:0034330 63 33 0,000 0,09198976 0,10861214 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,09198976 0,10855641 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,09198976 0,10850074 ! nucleus organization GO:0006997 49 33 0,000 0,09198976 0,10844513 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,09198976 0,10838958 ! female gonad development GO:0008585 49 33 0,000 0,09198976 0,10833408 ! positive regulation of cell development GO:0010720 54 33 0,000 0,09198976 0,10827863 ! lipid homeostasis GO:0055088 55 33 0,000 0,09198976 0,10822325 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,09198976 0,10816792 ! regulation of proteolysis GO:0030162 50 33 0,000 0,09198976 0,10811265 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,09198976 0,10805743 ! cytokinesis GO:0000910 52 33 0,000 0,09198976 0,10800227 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,09198976 0,10794717 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,0946437 0,11100485 ! mRNA catabolic process GO:0006402 48 34 0,000 0,0946437 0,11094827 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,0946437 0,11089175 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,0946437 0,11083529 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,0946437 0,11077888 ! feeding behavior GO:0007631 45 34 0,000 0,0946437 0,11072253 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,0946437 0,11066624 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,0946437 0,11061001 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,0946437 0,11055384 ! neuron migration GO:0001764 46 34 0,000 0,0946437 0,11049772 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,0946437 0,11044166 ! female gamete generation GO:0007292 43 34 0,000 0,0946437 0,11038565 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,0946437 0,1103297 ! polyol metabolic process GO:0019751 44 34 0,000 0,0946437 0,11027381 ! aerobic respiration GO:0009060 47 34 0,000 0,0946437 0,11021798 ! embryonic organ development GO:0048568 45 34 0,000 0,0946437 0,1101622 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,0946437 0,11010648 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,09729003 0,11312794 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,09729003 0,11307077 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,09729003 0,11301367 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,09729003 0,11295662 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,09729003 0,11289963 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,09729003 0,11284269 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 51 35 0,000 0,09729003 0,11278582 ! glycogen metabolic process GO:0005977 48 35 0,000 0,09729003 0,112729 ! pigment metabolic process GO:0042440 61 35 0,000 0,09729003 0,11267224 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,09992877 0,11566994 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,09992877 0,11561176 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,09992877 0,11555363 ! organic ether metabolic process GO:0018904 46 36 0,000 0,09992877 0,11549557 ! tissue remodeling GO:0048771 62 36 0,000 0,09992877 0,11543756 ! neural tube development GO:0021915 50 36 0,000 0,09992877 0,11537961 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,09992877 0,11532172 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,09992877 0,11526388 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,09992877 0,11520611 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,09992877 0,11514839 ! glucan metabolic process GO:0044042 49 36 0,000 0,09992877 0,11509073 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,10255996 0,11806201 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,10255996 0,11800295 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,10255996 0,11794395 ! learning GO:0007612 67 37 0,000 0,10255996 0,11788501 ! ion transmembrane transport GO:0034220 56 37 0,000 0,10255996 0,11782613 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,10255996 0,1177673 ! regulation of protein secretion GO:0050708 51 37 0,000 0,10255996 0,11770853 ! amino acid activation GO:0043038 52 37 0,000 0,10255996 0,11764983 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,10255996 0,11759118 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,1051836 0,12053925 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,1051836 0,12047922 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,1051836 0,12041925 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,1051836 0,12035934 ! phagocytosis GO:0006909 60 38 0,000 0,1051836 0,12029949 ! pigmentation GO:0043473 74 38 0,000 0,1051836 0,1202397 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,10779972 0,12316908 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,10779972 0,12310793 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,10779972 0,12304683 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,10779972 0,12298579 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,10779972 0,12292482 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,10779972 0,12286391 ! male sex differentiation GO:0046661 53 39 0,000 0,10779972 0,12280305 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,10779972 0,12274226 ! chromatin remodeling GO:0006338 68 39 0,000 0,10779972 0,12268152 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,10779972 0,12262085 ! JNK cascade GO:0007254 54 39 0,000 0,10779972 0,12256024 ! developmental growth GO:0048589 62 39 0,000 0,10779972 0,12249968 ! cell growth GO:0016049 61 39 0,000 0,10779972 0,12243919 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,11040835 0,12534017 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,11040835 0,12527834 ! regulation of tube size GO:0035150 60 40 0,000 0,11040835 0,12521657 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 0,000 0,11040835 0,12515485 ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,11040835 0,1250932 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,11040835 0,12503161 ! peptide metabolic process GO:0006518 56 40 0,000 0,11040835 0,12497008 ! inner ear development GO:0048839 57 40 0,000 0,11040835 0,12490861 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,11040835 0,12484719 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! epidermal cell differentiation GO:0009913 53 40 0,000 0,11040835 0,12478584 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,11040835 0,12472456 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,11300949 0,12760031 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,11300949 0,1275377 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,11300949 0,12747515 ! glucose transport GO:0015758 52 41 0,000 0,11300949 0,12741266 ! striated muscle contraction GO:0006941 62 41 0,000 0,11300949 0,12735023 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,11300949 0,12728787 ! biopolymer methylation GO:0043414 62 41 0,000 0,11300949 0,12722556 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,11300949 0,12716332 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,11560318 0,13001825 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,11560318 0,1299547 ! cellular component disassembly GO:0022411 64 42 0,000 0,11560318 0,12989121 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,11560318 0,12982779 ! hexose transport GO:0008645 54 42 0,000 0,11560318 0,12976443 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,11560318 0,12970113 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,11560318 0,12963789 ! excretion GO:0007588 63 42 0,000 0,11560318 0,12957471 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,11560318 0,1295116 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,11560318 0,12944854 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,11560318 0,12938555 ! regulation of cell shape GO:0008360 78 42 0,000 0,11560318 0,12932262 ! leukocyte migration GO:0050900 60 43 0,000 0,11818943 0,13215153 ! neuromuscular process GO:0050905 79 43 0,000 0,11818943 0,13208731 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,11818943 0,13202316 ! tRNA processing GO:0008033 49 43 0,000 0,11818943 0,13195907 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,11818943 0,13189505 ! vesicle organization GO:0016050 79 43 0,000 0,11818943 0,13183108 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,11818943 0,13176718 ! methylation GO:0032259 64 43 0,000 0,11818943 0,13170334 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,12076827 0,13451187 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,12076827 0,13444676 ! glycolysis GO:0006096 53 44 0,000 0,12076827 0,13438172 ! regulation of ion transport GO:0043269 57 44 0,000 0,12076827 0,13431674 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,12076827 0,13425182 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,12076827 0,13418696 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,12076827 0,13412217 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,12076827 0,13405744 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,12076827 0,13399277 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,12076827 0,13392817 ! RNA catabolic process GO:0006401 64 45 0,000 0,12333971 0,1367139 ! positive regulation of defense response GO:0031349 59 45 0,000 0,12333971 0,13664804 ! regulation of translational initiation GO:0006446 64 45 0,000 0,12333971 0,13658225 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,12333971 0,13651652 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,12333971 0,13645086 ! cell recognition GO:0008037 58 45 0,000 0,12333971 0,13638526 ! cell maturation GO:0048469 60 45 0,000 0,12333971 0,13631972 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,12590378 0,13908679 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,12590378 0,13902002 ! cell redox homeostasis GO:0045454 63 46 0,000 0,12590378 0,13895331 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,12590378 0,13888666 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,12590378 0,13882008 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,1284605 0,14157122 ! viral infectious cycle GO:0019058 71 47 0,000 0,1284605 0,14150342 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,1284605 0,14143568 ! endocrine system development GO:0035270 83 47 0,000 0,1284605 0,14136801 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,1284605 0,1413004 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,1284605 0,14123286 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,1284605 0,14116538 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,1284605 0,14109797 ! chloride transport GO:0006821 67 48 0,000 0,13100988 0,14382946 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,13100988 0,14376084 ! response to temperature stimulus GO:0009266 62 48 0,000 0,13100988 0,14369229 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,13100988 0,1436238 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,13100988 0,14355537 ! gastrulation GO:0007369 73 48 0,000 0,13100988 0,14348701 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,13100988 0,14341872 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,13100988 0,14335049 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,13100988 0,14328232 ! regulation of endocytosis GO:0030100 63 48 0,000 0,13100988 0,14321422 ! nuclear export GO:0051168 69 48 0,000 0,13100988 0,14314619 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,13100988 0,14307822 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,13355195 0,14578524 ! sensory perception of smell GO:0007608 61 49 0,000 0,13355195 0,14571608 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,13355195 0,14564699 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,13355195 0,14557796 ! RNA elongation GO:0006354 62 49 0,000 0,13355195 0,145509 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,13355195 0,1454401 ! germ cell development GO:0007281 68 49 0,000 0,13355195 0,14537127 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,13355195 0,1453025 ! cartilage development GO:0051216 70 49 0,000 0,13355195 0,1452338 ! regulation of actin filament length GO:0030832 72 50 0,000 0,13608674 0,14792036 ! ear development GO:0043583 72 50 0,000 0,13608674 0,14785049 ! membrane fusion GO:0006944 80 50 0,000 0,13608674 0,14778068 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,13608674 0,14771094 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,13608674 0,14764127 ! proton transport GO:0015992 75 50 0,000 0,13608674 0,14757166 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,13608674 0,14750212 ! positive regulation of secretion GO:0051047 71 51 0,000 0,13861425 0,15017087 ! hydrogen transport GO:0006818 77 51 0,000 0,13861425 0,15010017 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,13861425 0,15002954 ! adult behavior GO:0030534 80 51 0,000 0,13861425 0,14995897 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,13861425 0,14988847 ! transition metal ion transport GO:0000041 74 52 0,000 0,14113451 0,152542 ! regulation of cellular component size GO:0032535 74 52 0,000 0,14113451 0,15247035 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,14113451 0,15239876 ! establishment of organelle localization GO:0051656 85 52 0,000 0,14113451 0,15232725 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,14364754 0,15496686 ! kidney development GO:0001822 90 53 0,000 0,14364754 0,15489421 ! single fertilization GO:0007338 59 53 0,000 0,14364754 0,15482162 ! amino acid transport GO:0006865 84 54 0,000 0,14615336 0,15744859 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,14615336 0,15737487 ! regulation of mitosis GO:0007088 84 54 0,000 0,14615336 0,15730123 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,14615336 0,15722766 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,14615336 0,15715415 ! DNA catabolic process GO:0006308 67 54 0,000 0,14615336 0,15708072 ! detection of external stimulus GO:0009581 66 54 0,000 0,14615336 0,15700735 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,14615336 0,15693405 ! exocytosis GO:0006887 74 55 0,000 0,14865199 0,1595425 ! mesoderm development GO:0007498 76 55 0,000 0,14865199 0,15946809 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,14865199 0,15939375 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,14865199 0,15931947 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,15114346 0,16191428 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,15114346 0,1618389 ! carbohydrate transport GO:0008643 74 57 0,000 0,15362777 0,16442247 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,15362777 0,16434599 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,15362777 0,16426959 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,15362777 0,16419325 ! camera-type eye development GO:0043010 88 57 0,000 0,15362777 0,16411699 ! secondary metabolic process GO:0019748 84 57 0,000 0,15362777 0,1640408 ! developmental maturation GO:0021700 75 57 0,000 0,15362777 0,16396468 ! gonad development GO:0008406 79 57 0,000 0,15362777 0,16388863 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,15610496 0,16645406 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,15857504 0,16900954 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,15857504 0,16893126 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,15857504 0,16885305 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,16103803 0,17139633 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,16103803 0,17131705 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,16103803 0,17123785 ! regulation of heart contraction GO:0008016 91 60 0,000 0,16103803 0,17115872 ! fertilization GO:0009566 68 60 0,000 0,16103803 0,17107966 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,16349395 0,17360854 ! meiosis GO:0007126 96 61 0,000 0,16349395 0,17352842 GO:0051327|M phase of meiotic cell cycle, ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,16349395 0,17344838 ! urogenital system development GO:0001655 101 61 0,000 0,16349395 0,17336841 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,16349395 0,17328852 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,16349395 0,1732087 ! extracellular matrix organization GO:0030198 103 61 0,000 0,16349395 0,17312895 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,16349395 0,17304928 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,16349395 0,17296968 ! amine catabolic process GO:0009310 90 62 0,000 0,16594282 0,17547977 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,16594282 0,17539912 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,16594282 0,17531856 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,16594282 0,17523806 ! meiotic cell cycle GO:0051321 97 62 0,000 0,16594282 0,17515764 ! organelle localization GO:0051640 96 62 0,000 0,16594282 0,17507729 ! appendage morphogenesis GO:0035107 93 64 0,000 0,1708195 0,18013978 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,1708195 0,18005722 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,1708195 0,17997474 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,1708195 0,17989233 ! hexose catabolic process GO:0019320 82 64 0,000 0,1708195 0,17981 ! adaptive immune response GO:0002250 94 64 0,000 0,1708195 0,17972775 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 0,000 0,17324735 0,18219886 ! appendage development GO:0048736 94 65 0,000 0,17324735 0,18211558 GO:0060173|limb development, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,17324735 0,18203239 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,17324735 0,18194927 ! defense response to bacterium GO:0042742 73 65 0,000 0,17324735 0,18186622 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,17324735 0,18178326 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,17324735 0,18170036 ! activation of immune response GO:0002253 83 65 0,000 0,17324735 0,18161755 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,17566822 0,18407149 ! antigen processing and presentation GO:0019882 96 66 0,000 0,17566822 0,18398766 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,17566822 0,18390392 ! regulation of immune effector process GO:0002697 101 66 0,000 0,17566822 0,18382025 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,17808215 0,18626145 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,17808215 0,18617679 ! acute inflammatory response GO:0002526 92 68 0,000 0,18048914 0,18860746 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,18048914 0,18852181 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,18048914 0,18843624 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,18048914 0,18835074 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,18048914 0,18826532 ! rhythmic process GO:0048511 105 68 0,000 0,18048914 0,18817998 ! inorganic anion transport GO:0015698 93 68 0,000 0,18048914 0,18809471 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,18288923 0,19050961 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,18288923 0,19042337 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,18528242 0,19282785 ! humoral immune response GO:0006959 86 70 0,000 0,18528242 0,19274064 ! eye development GO:0001654 111 70 0,000 0,18528242 0,19265351 ! amine transport GO:0015837 101 70 0,000 0,18528242 0,19256645 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,18528242 0,19247948 ! muscle cell differentiation GO:0042692 104 71 0,000 0,18766874 0,19487047 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,18766874 0,19478253 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,18766874 0,19469468 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,18766874 0,1946069 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,18766874 0,1945192 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,1900482 0,19689679 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,1900482 0,19680814 ! regulation of blood pressure GO:0008217 107 73 0,000 0,19242084 0,19917548 ! tube morphogenesis GO:0035239 118 73 0,000 0,19242084 0,19908589 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,19242084 0,19899637 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,19242084 0,19890693 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,19478666 0,20126204 ! digestion GO:0007586 97 74 0,000 0,19478666 0,20117167 ! blood coagulation GO:0007596 116 75 0,000 0,19714568 0,20351663 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 0,000 0,19714568 0,20342533 ! regulation of ligase activity GO:0051340 114 75 0,000 0,19714568 0,20333411 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,19714568 0,20324297 ! amine biosynthetic process GO:0009309 97 76 0,000 0,19949793 0,20557582 ! tRNA metabolic process GO:0006399 95 76 0,000 0,19949793 0,20548376 ! response to unfolded protein GO:0006986 99 76 0,000 0,19949793 0,20539178 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,19949793 0,20529988 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,20184342 0,20762069 ! sex differentiation GO:0007548 105 77 0,000 0,20184342 0,20752788 ! protein ubiquitination GO:0016567 125 77 0,000 0,20184342 0,20743515 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,20184342 0,2073425 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,20184342 0,20724994 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,20184342 0,20715746 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,20418217 0,20946431 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,20418217 0,20937093 ! cellular respiration GO:0045333 107 79 0,000 0,2065142 0,21166785 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,2065142 0,21157357 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,2065142 0,21147937 ! chromatin assembly GO:0031497 102 80 0,000 0,20883954 0,21376543 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,20883954 0,21367034 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,20883954 0,21357534 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,20883954 0,21348041 ! forebrain development GO:0030900 131 80 0,000 0,20883954 0,21338558 ! hemostasis GO:0007599 125 81 0,000 0,21115819 0,2156589 ! mRNA transport GO:0051028 121 81 0,000 0,21115819 0,21556317 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,21115819 0,21546754 ! response to protein stimulus GO:0051789 111 81 0,000 0,21115819 0,21537199 ! regulation of neurological system process GO:0031644 122 81 0,000 0,21115819 0,21527652 ! vitamin metabolic process GO:0006766 103 81 0,000 0,21115819 0,21518114 ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,21577552 0,21978906 ! regulation of defense response GO:0031347 117 84 0,000 0,21807424 0,22203221 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,21807424 0,22193397 ! sterol metabolic process GO:0016125 120 84 0,000 0,21807424 0,22183581 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,22036636 0,22406836 ! rRNA metabolic process GO:0016072 107 85 0,000 0,22036636 0,22396934 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,22036636 0,22387042 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,22036636 0,22377158 ! nucleosome organization GO:0034728 114 87 0,000 0,22493084 0,2283058 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,22493084 0,22820509 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,22493084 0,22810447 ! female pregnancy GO:0007565 130 87 0,000 0,22493084 0,22800394 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,22720325 0,23020594 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,22720325 0,23010457 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,22720325 0,23000329 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,22720325 0,2299021 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,22946913 0,23209278 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,23172849 0,23427496 ! hormone metabolic process GO:0042445 121 90 0,000 0,23172849 0,23417202 ! RNA localization GO:0006403 135 91 0,000 0,23398135 0,2363448 ! ATP metabolic process GO:0046034 137 91 0,000 0,23398135 0,23624105 ! response to virus GO:0009615 122 91 0,000 0,23398135 0,23613739 ! positive regulation of immune response GO:0050778 121 92 0,000 0,23622774 0,23829992 ! DNA recombination GO:0006310 146 92 0,000 0,23622774 0,23819545 ! sulfur metabolic process GO:0006790 118 92 0,000 0,23622774 0,23809107 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,23846767 0,24024339 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,23846767 0,2401382 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,23846767 0,24003311 ! electron transport chain GO:0022900 123 94 0,000 0,24070116 0,24217527 ! response to oxidative stress GO:0006979 141 94 0,000 0,24070116 0,24206938 ! carboxylic acid transport GO:0046942 147 95 0,000 0,24292823 0,24420233 GO:0015849|organic acid transport, ! regulation of response to external stimulus GO:0032101 139 96 0,000 0,24514889 0,24632698 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,24514889 0,24621941 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,24514889 0,24611194 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,24514889 0,24600456 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,24736317 0,24811831 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,25177263 0,25243115 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 0,000 0,25177263 0,25232116 ! regulation of translation GO:0006417 151 100 0,000 0,25396786 0,25441031 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,25396786 0,25429955 ! divalent metal ion transport GO:0070838 171 100 0,000 0,25396786 0,25418889 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,25396786 0,25407833 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,25396786 0,25396786