pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6515-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Notch receptor processing GO:0007220 8 5 2,000 1,478E-07 3,556E-04 ! amyloid precursor protein catabolic process GO:0042987 11 7 2,000 5,154E-07 6,201E-04 ! regulation of fibroblast proliferation GO:0048145 52 27 3,000 5,96E-07 4,78E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 8,232E-07 4,952E-04 ! amyloid precursor protein metabolic process GO:0042982 14 9 2,000 1,233E-06 5,931E-04 ! protein oligomerization GO:0051259 139 78 4,000 1,532E-06 6,145E-04 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 2,000 1,758E-06 6,042E-04 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 2,000 3,211E-06 9,657E-04 ! membrane protein proteolysis GO:0033619 25 12 2,000 3,211E-06 8,584E-04 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 4,066E-06 9,783E-04 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 4,07E-06 8,902E-04 ! interphase GO:0051325 213 98 4,000 4,743E-06 9,509E-04 ! glycoprotein catabolic process GO:0006516 26 15 2,000 6,605E-06 1,222E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 6,605E-06 1,135E-03 ! positive regulation of protein import into nucleus GO:0042307 30 16 2,000 8,115E-06 1,302E-03 ! response to UV GO:0009411 104 53 3,000 9,468E-06 1,424E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 9,836E-06 1,392E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 1,268E-05 1,694E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 1,556E-05 1,97E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 1,64E-05 1,973E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 1,64E-05 1,879E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 2,208E-05 2,414E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 2,208E-05 2,309E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 2,414E-05 2,42E-03 ! positive regulation of cell adhesion GO:0045785 56 23 2,000 2,534E-05 2,439E-03 ! negative regulation of kinase activity GO:0033673 131 68 3,000 2,56E-05 2,369E-03 ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 2,891E-05 2,576E-03 ! protein tetramerization GO:0051262 52 24 2,000 2,891E-05 2,484E-03 ! negative regulation of transferase activity GO:0051348 140 72 3,000 3,21E-05 2,663E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 3,28E-05 2,63E-03 ! regulation of transcription factor import into nucleus GO:0042990 54 26 2,000 3,701E-05 2,872E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 3,701E-05 2,782E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 5,173E-05 3,772E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 6,089E-05 4,309E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 6,089E-05 4,186E-03 ! lymph vessel development GO:0001945 10 5 1,000 6,089E-05 4,07E-03 ! microvillus organization GO:0032528 7 5 1,000 6,089E-05 3,96E-03 GO:0030033|microvillus assembly, ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 6,089E-05 3,856E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 6,089E-05 3,757E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 6,089E-05 3,663E-03 ! regulation of protein import into nucleus GO:0042306 63 32 2,000 6,984E-05 4,099E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 8,756E-05 5,016E-03 ! activation of MAPKKK activity GO:0000185 12 6 1,000 9,119E-05 5,103E-03 ! male sex determination GO:0030238 15 6 1,000 9,119E-05 4,987E-03 ! neural nucleus development GO:0048857 14 6 1,000 9,119E-05 4,876E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 9,119E-05 4,77E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 9,119E-05 4,668E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 9,982E-05 5,004E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 1,084E-04 5,325E-03 ! cell cycle arrest GO:0007050 213 100 3,000 1,161E-04 5,585E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 1,275E-04 6,013E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,275E-04 5,898E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 1,275E-04 5,786E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 1,275E-04 5,679E-03 ! cranial nerve morphogenesis GO:0021602 11 7 1,000 1,275E-04 5,576E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 1,275E-04 5,476E-03 ! response to tumor cell GO:0002347 13 7 1,000 1,275E-04 5,38E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 1,275E-04 5,288E-03 ! positive regulation of ATPase activity GO:0032781 11 7 1,000 1,275E-04 5,198E-03 ! mesenchymal cell development GO:0014031 87 40 2,000 1,371E-04 5,5E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! T cell differentiation GO:0030217 81 41 2,000 1,477E-04 5,826E-03 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 1,588E-04 6,162E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,697E-04 6,48E-03 ! endothelial cell differentiation GO:0045446 17 8 1,000 1,697E-04 6,379E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,697E-04 6,281E-03 ! ER overload response GO:0006983 12 8 1,000 1,697E-04 6,186E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 1,697E-04 6,093E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 1,952E-04 6,907E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 2,085E-04 7,269E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 2,085E-04 7,165E-03 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 2,085E-04 7,065E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 2,085E-04 6,966E-03 ! positive regulation of protein transport GO:0051222 72 46 2,000 2,085E-04 6,871E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 2,178E-04 7,082E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 2,178E-04 6,987E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 2,178E-04 6,895E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 2,178E-04 6,806E-03 ! receptor clustering GO:0043113 18 9 1,000 2,178E-04 6,719E-03 ! motor axon guidance GO:0008045 16 9 1,000 2,178E-04 6,633E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 2,178E-04 6,551E-03 ! protein homooligomerization GO:0051260 76 47 2,000 2,223E-04 6,603E-03 ! Notch signaling pathway GO:0007219 96 48 2,000 2,367E-04 6,945E-03 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 2,367E-04 6,861E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 2,718E-04 7,786E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 2,718E-04 7,694E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 2,718E-04 7,605E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 2,718E-04 7,517E-03 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 1,000 2,718E-04 7,432E-03 ! localization within membrane GO:0051668 20 10 1,000 2,718E-04 7,348E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 2,835E-04 7,578E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 3,317E-04 8,77E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 3,317E-04 8,674E-03 ! regulation of intracellular pH GO:0051453 19 11 1,000 3,317E-04 8,581E-03 ! regulation of embryonic development GO:0045995 27 11 1,000 3,317E-04 8,49E-03 ! regulation of DNA replication GO:0006275 101 56 2,000 3,739E-04 9,471E-03 ! positive regulation of cell migration GO:0030335 126 57 2,000 3,94E-04 9,875E-03 ! regulation of intracellular transport GO:0032386 101 57 2,000 3,94E-04 9,773E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 3,974E-04 9,756E-03 ! virus-host interaction GO:0019048 29 12 1,000 3,974E-04 9,658E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 3,974E-04 9,561E-03 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 3,974E-04 9,466E-03 ! cranial nerve development GO:0021545 20 12 1,000 3,974E-04 9,374E-03 ! histone acetylation GO:0016573 26 12 1,000 3,974E-04 9,283E-03 ! autonomic nervous system development GO:0048483 24 12 1,000 3,974E-04 9,193E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 3,974E-04 9,106E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 3,974E-04 9,02E-03 GO:0042130|negative regulation of T cell proliferation, ! response to X-ray GO:0010165 25 13 1,000 4,689E-04 0,01054316 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 4,689E-04 0,01044554 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 4,689E-04 0,01034971 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 4,689E-04 0,01025562 ! regulation of calcium-mediated signaling GO:0050848 25 13 1,000 4,689E-04 0,01016323 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 4,689E-04 0,01007249 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 4,812E-04 0,01024555 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 5,291E-04 0,01116575 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 5,461E-04 0,01142622 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 5,461E-04 0,01132772 ! response to gamma radiation GO:0010332 28 14 1,000 5,461E-04 0,0112309 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 5,461E-04 0,01113572 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 5,461E-04 0,01104215 ! positive regulation of cell motion GO:0051272 146 64 2,000 5,541E-04 0,01110929 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 6,291E-04 0,01251014 ! regulation of exocytosis GO:0017157 22 15 1,000 6,291E-04 0,0124076 ! G1/S transition checkpoint GO:0031575 40 15 1,000 6,291E-04 0,01230672 ! regulation of ATPase activity GO:0043462 21 15 1,000 6,291E-04 0,01220747 ! negative regulation of cell growth GO:0030308 132 67 2,000 6,337E-04 0,012197 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 6,617E-04 0,01263611 ! protein maturation by peptide bond cleavage GO:0051605 105 68 2,000 6,617E-04 0,01253661 ! negative regulation of cell size GO:0045792 134 69 2,000 6,906E-04 0,01298089 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 7,179E-04 0,01338902 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 7,179E-04 0,01328603 ! activation of MAPKK activity GO:0000186 35 16 1,000 7,179E-04 0,01318461 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 7,179E-04 0,01308473 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 7,179E-04 0,01298635 ! regulation of caspase activity GO:0043281 122 72 2,000 7,819E-04 0,01403919 ! signal complex assembly GO:0007172 41 17 1,000 8,123E-04 0,01447644 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 8,123E-04 0,01437 ! regulation of transcription factor activity GO:0051090 126 74 2,000 8,468E-04 0,01487223 GO:0090046|regulation of transcription regulator activity, ! regulation of endopeptidase activity GO:0052548 125 74 2,000 8,468E-04 0,01476446 ! lymphocyte differentiation GO:0030098 167 75 2,000 8,806E-04 0,0152418 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 9,123E-04 0,01567905 ! centrosome cycle GO:0007098 25 18 1,000 9,123E-04 0,01556785 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 9,123E-04 0,01545821 ! nerve development GO:0021675 28 18 1,000 9,123E-04 0,01535011 ! regulation of catabolic process GO:0009894 161 76 2,000 9,151E-04 0,01528992 ! lipid phosphorylation GO:0046834 35 19 1,000 1,018E-03 0,01689211 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 1,018E-03 0,01677641 ! neuromuscular junction development GO:0007528 34 19 1,000 1,018E-03 0,01666229 ! G1 phase GO:0051318 40 19 1,000 1,018E-03 0,0165497 ! regulation of peptidase activity GO:0052547 134 79 2,000 1,024E-03 0,01653353 ! T cell activation GO:0042110 168 81 2,000 1,101E-03 0,01765642 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 1,129E-03 0,01799419 ! protein amino acid acetylation GO:0006473 39 20 1,000 1,129E-03 0,0178758 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 1,129E-03 0,01775897 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 1,129E-03 0,01764365 ! cellular response to starvation GO:0009267 33 20 1,000 1,129E-03 0,01752982 ! detection of chemical stimulus GO:0009593 37 20 1,000 1,129E-03 0,01741745 ! negative regulation of T cell activation GO:0050868 40 20 1,000 1,129E-03 0,01730651 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 1,129E-03 0,01719698 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 1,141E-03 0,01725877 ! negative regulation of growth GO:0045926 155 84 2,000 1,223E-03 0,01838748 ! cell aging GO:0007569 44 21 1,000 1,246E-03 0,01862296 ! regulation of protein transport GO:0051223 154 87 2,000 1,353E-03 0,02009429 GO:0070201|regulation of establishment of protein localization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 1,369E-03 0,02020132 ! positive regulation of B cell activation GO:0050871 38 22 1,000 1,369E-03 0,02007814 ! protein stabilization GO:0050821 39 22 1,000 1,369E-03 0,01995646 ! regulation of DNA binding GO:0051101 155 88 2,000 1,398E-03 0,0202661 ! regulation of cell adhesion GO:0030155 212 89 2,000 1,444E-03 0,02081039 ! positive regulation of DNA replication GO:0045740 43 23 1,000 1,497E-03 0,0214322 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 1,497E-03 0,02130538 GO:0010810|regulation of cell-substrate adhesion, ! sex determination GO:0007530 47 23 1,000 1,497E-03 0,02118006 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 1,497E-03 0,0210562 ! negative regulation of catabolic process GO:0009895 50 23 1,000 1,497E-03 0,02093378 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 1,63E-03 0,02266829 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 1,63E-03 0,02253801 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 1,63E-03 0,02240922 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 1,63E-03 0,0222819 ! myelination GO:0042552 45 25 1,000 1,769E-03 0,02404385 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 1,769E-03 0,02390878 ! negative regulation of DNA replication GO:0008156 42 25 1,000 1,769E-03 0,02377521 ! receptor metabolic process GO:0043112 46 25 1,000 1,769E-03 0,02364312 ! response to starvation GO:0042594 42 25 1,000 1,769E-03 0,0235125 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 1,769E-03 0,02338331 ! negative regulation of cell development GO:0010721 73 25 1,000 1,769E-03 0,02325553 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 1,769E-03 0,02312914 ! somitogenesis GO:0001756 43 25 1,000 1,769E-03 0,02300412 ! cellular response to nutrient levels GO:0031669 41 25 1,000 1,769E-03 0,02288044 ! leukocyte differentiation GO:0002521 202 96 2,000 1,795E-03 0,02309278 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 1,849E-03 0,0236609 ! regulation of protein localization GO:0032880 176 97 2,000 1,849E-03 0,02353571 ! microtubule organizing center organization GO:0031023 39 26 1,000 1,913E-03 0,02422626 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 1,913E-03 0,02409942 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 1,913E-03 0,0239739 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 1,913E-03 0,02384968 ! skeletal muscle tissue development GO:0007519 186 99 2,000 1,96E-03 0,02430575 GO:0060538|skeletal muscle organ development, ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 2,063E-03 0,02545246 ! protein amino acid acylation GO:0043543 55 27 1,000 2,063E-03 0,0253226 ! mitochondrial membrane organization GO:0007006 57 27 1,000 2,063E-03 0,02519406 ! base-excision repair GO:0006284 41 27 1,000 2,063E-03 0,02506681 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 2,063E-03 0,02494085 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 2,218E-03 0,02668208 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 2,218E-03 0,02654934 ! regulation of pH GO:0006885 43 29 1,000 2,378E-03 0,02832914 ! cell fate determination GO:0001709 60 29 1,000 2,378E-03 0,02818959 ! ensheathment of neurons GO:0007272 57 30 1,000 2,544E-03 0,03000674 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 2,544E-03 0,02986037 ! neurotransmitter secretion GO:0007269 48 30 1,000 2,544E-03 0,02971542 ! regulation of B cell activation GO:0050864 50 30 1,000 2,544E-03 0,02957186 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 2,715E-03 0,03140874 GO:0043433|negative regulation of transcription factor activity, ! response to ionizing radiation GO:0010212 65 32 1,000 2,892E-03 0,03328875 ! peripheral nervous system development GO:0007422 64 32 1,000 2,892E-03 0,03313024 ! hindbrain development GO:0030902 61 32 1,000 2,892E-03 0,03297322 ! positive regulation of catabolic process GO:0009896 64 32 1,000 2,892E-03 0,03281769 ! DNA damage checkpoint GO:0000077 71 33 1,000 3,073E-03 0,03471505 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 3,073E-03 0,03455283 ! negative regulation of protein transport GO:0051224 69 33 1,000 3,073E-03 0,03439212 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 3,26E-03 0,036314 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 3,452E-03 0,03827576 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 3,452E-03 0,03810019 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 3,452E-03 0,03792621 ! calcium-mediated signaling GO:0019722 62 35 1,000 3,452E-03 0,03775382 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 3,649E-03 0,03972982 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! maintenance of protein location in cell GO:0032507 86 36 1,000 3,649E-03 0,03955086 ! DNA integrity checkpoint GO:0031570 75 36 1,000 3,649E-03 0,0393735 ! negative regulation of cell activation GO:0050866 65 36 1,000 3,649E-03 0,03919773 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 3,852E-03 0,04118717 ! negative regulation of DNA binding GO:0043392 68 37 1,000 3,852E-03 0,04100493 ! regulation of protein stability GO:0031647 73 37 1,000 3,852E-03 0,04082429 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 4,059E-03 0,0428344 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 4,059E-03 0,04264735 ! carbohydrate homeostasis GO:0033500 53 38 1,000 4,059E-03 0,04246193 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 4,059E-03 0,04227811 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 1,000 4,272E-03 0,04430009 ! segmentation GO:0035282 67 39 1,000 4,272E-03 0,04410996 ! regulation of action potential in neuron GO:0019228 73 39 1,000 4,272E-03 0,04392146 ! negative regulation of binding GO:0051100 72 40 1,000 4,489E-03 0,04596247 ! maintenance of protein location GO:0045185 91 40 1,000 4,489E-03 0,04576772 ! regulation of T cell differentiation GO:0045580 70 41 1,000 4,712E-03 0,04783486 ! gliogenesis GO:0042063 88 41 1,000 4,712E-03 0,04763388 ! regulation of T cell proliferation GO:0042129 71 41 1,000 4,712E-03 0,04743457 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 4,712E-03 0,04723693 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 4,94E-03 0,04931371 GO:0090047|positive regulation of transcription regulator activity, ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 4,94E-03 0,04910993 ! double-strand break repair GO:0006302 81 44 1,000 5,41E-03 0,05356385 ! B cell differentiation GO:0030183 107 44 1,000 5,41E-03 0,05334433 ! maintenance of location in cell GO:0051651 97 44 1,000 5,41E-03 0,0531266 ! response to calcium ion GO:0051592 81 47 1,000 6,152E-03 0,06017091 ! endosome transport GO:0016197 108 47 1,000 6,152E-03 0,0599273 ! positive regulation of DNA binding GO:0043388 73 47 1,000 6,152E-03 0,05968566 ! positive regulation of cell cycle GO:0045787 89 48 1,000 6,409E-03 0,06193113 ! mitochondrial transport GO:0006839 82 48 1,000 6,409E-03 0,06168341 ! activation of caspase activity GO:0006919 84 48 1,000 6,409E-03 0,06143766 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 6,409E-03 0,06119386 ! regulation of action potential GO:0001508 95 49 1,000 6,671E-03 0,06344384 ! regulation of ossification GO:0030278 117 50 1,000 6,938E-03 0,06572167 ! histone modification GO:0016570 91 50 1,000 6,938E-03 0,06546394 ! negative regulation of immune system process GO:0002683 95 50 1,000 6,938E-03 0,06520822 ! positive regulation of binding GO:0051099 78 51 1,000 7,21E-03 0,06749738 ! embryonic skeletal system development GO:0048706 85 51 1,000 7,21E-03 0,06723576 ! regulation of angiogenesis GO:0045765 114 52 1,000 7,486E-03 0,06954364 ! positive regulation of growth GO:0045927 90 52 1,000 7,486E-03 0,06927616 ! covalent chromatin modification GO:0016569 101 52 1,000 7,486E-03 0,06901074 ! synapse organization GO:0050808 85 52 1,000 7,486E-03 0,06874734 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 7,767E-03 0,07105768 ! activation of phospholipase C activity GO:0007202 103 54 1,000 8,053E-03 0,07339345 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 8,053E-03 0,07311649 ! positive regulation of caspase activity GO:0043280 95 55 1,000 8,344E-03 0,07546935 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 8,344E-03 0,07518669 ! regulation of protein catabolic process GO:0042176 116 55 1,000 8,344E-03 0,07490614 ! aging GO:0007568 103 55 1,000 8,344E-03 0,07462768 ! heart morphogenesis GO:0003007 97 55 1,000 8,344E-03 0,07435128 ! skeletal muscle fiber development GO:0048741 111 56 1,000 8,639E-03 0,07669755 ! nucleotide-excision repair GO:0006289 83 56 1,000 8,639E-03 0,07641557 ! regulation of bone remodeling GO:0046850 137 57 1,000 8,939E-03 0,07877796 ! muscle fiber development GO:0048747 112 57 1,000 8,939E-03 0,07849045 ! lipid modification GO:0030258 97 57 1,000 8,939E-03 0,07820503 ! regulation of phospholipase activity GO:0010517 106 57 1,000 8,939E-03 0,07792168 ! maintenance of location GO:0051235 118 57 1,000 8,939E-03 0,07764037 ! regulation of tissue remodeling GO:0034103 140 58 1,000 9,243E-03 0,07999578 ! positive regulation of lipase activity GO:0060193 108 58 1,000 9,243E-03 0,07970906 ! skeletal system morphogenesis GO:0048705 105 59 1,000 9,552E-03 0,08207969 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 9,552E-03 0,08178759 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 9,866E-03 0,08417298 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 9,866E-03 0,08387555 ! viral reproductive process GO:0022415 126 62 1,000 0,01050641 0,08900855 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,01050641 0,08869624 ! cell projection assembly GO:0030031 120 66 1,000 0,01184164 0,09961881 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,01184164 0,09927171 ! actin filament organization GO:0007015 148 66 1,000 0,01184164 0,09892701 ! activation of MAPK activity GO:0000187 115 67 1,000 0,0121865 0,10145576 ! lung development GO:0030324 144 67 1,000 0,0121865 0,10110591 ! chromosome segregation GO:0007059 113 67 1,000 0,0121865 0,10075847 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,0121865 0,1004134 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,0123904 0,10174504 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,0123904 0,10139896 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,0123904 0,10105524 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,0123904 0,10071384 ! neuron fate determination GO:0048664 7 5 0,000 0,0123904 0,10037473 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0123904 0,1000379 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,0123904 0,09970333 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,0123904 0,09937098 ! polyol transport GO:0015791 12 5 0,000 0,0123904 0,09904085 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,0123904 0,0987129 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,0123904 0,09838711 ! response to superoxide GO:0000303 10 5 0,000 0,0123904 0,09806347 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,0123904 0,09774195 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,0123904 0,09742253 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,0123904 0,0971052 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,0123904 0,09678992 ! female meiosis GO:0007143 7 5 0,000 0,0123904 0,09647668 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,0123904 0,09616547 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,0123904 0,09585625 ! cobalt ion transport GO:0006824 11 5 0,000 0,0123904 0,09554902 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,0123904 0,09524375 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,0123904 0,09494043 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,0123904 0,09463903 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,0123904 0,09433954 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,0123904 0,09404194 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,0123904 0,09374621 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,0123904 0,09345234 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,0123904 0,0931603 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,0123904 0,09287008 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,0123904 0,09258166 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0123904 0,09229503 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,0123904 0,09201017 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,0123904 0,09172706 ! negative chemotaxis GO:0050919 14 5 0,000 0,0123904 0,09144569 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,0123904 0,09116604 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,0123904 0,0908881 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,0123904 0,09061184 ! behavioral response to pain GO:0048266 9 5 0,000 0,0123904 0,09033726 ! clathrin coat assembly GO:0048268 14 5 0,000 0,0123904 0,09006434 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0123904 0,08979306 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,0123904 0,08952341 ! micturition GO:0060073 9 5 0,000 0,0123904 0,08925538 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,0123904 0,08898894 ! copulation GO:0007620 9 5 0,000 0,0123904 0,08872409 ! glial cell fate commitment GO:0021781 13 5 0,000 0,0123904 0,08846082 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,0123904 0,0881991 ! spermidine metabolic process GO:0008216 7 5 0,000 0,0123904 0,08793892 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,0123904 0,08768028 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,0123904 0,08742315 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,0123904 0,08716753 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,0123904 0,0869134 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,0123904 0,08666074 ! grooming behavior GO:0007625 6 5 0,000 0,0123904 0,08640955 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,0123904 0,08615981 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,0123904 0,08591151 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0123904 0,08566464 ! response to protozoan GO:0001562 10 5 0,000 0,0123904 0,08541918 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,0123904 0,08517513 ! endochondral ossification GO:0001958 16 5 0,000 0,0123904 0,08493247 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,0123904 0,08469118 ! parathyroid gland development GO:0060017 13 5 0,000 0,0123904 0,08445126 ! anagen GO:0042640 6 5 0,000 0,0123904 0,0842127 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,0123904 0,08397548 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,0123904 0,08373959 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,0123904 0,08350503 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,0123904 0,08327177 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,0123904 0,08303982 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,0123904 0,08280915 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,0123904 0,08257977 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,0123904 0,08235164 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,0123904 0,08212478 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,0123904 0,08189916 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,0123904 0,08167478 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,0123904 0,08145163 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,0123904 0,08122969 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,0123904 0,08100895 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,0123904 0,08078942 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,0123904 0,08057107 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,0123904 0,0803539 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,0123904 0,08013789 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,0123904 0,07992304 ! histidine catabolic process GO:0006548 6 5 0,000 0,0123904 0,07970935 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,0123904 0,07949679 ! valine metabolic process GO:0006573 10 5 0,000 0,0123904 0,07928536 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,0123904 0,07907505 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,0123904 0,07886586 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,0123904 0,07865777 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,0123904 0,07845078 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,0123904 0,07824487 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,0123904 0,07804004 ! polyol catabolic process GO:0046174 7 5 0,000 0,0123904 0,07783628 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,0123904 0,07763358 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,0123904 0,07743194 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,0123904 0,07723133 ! muscle cell migration GO:0014812 8 5 0,000 0,0123904 0,07703177 ! mitochondrial fission GO:0000266 8 5 0,000 0,0123904 0,07683324 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,0123904 0,07663572 ! mRNA transcription GO:0009299 9 5 0,000 0,0123904 0,07643922 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,0123904 0,07624372 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,0123904 0,07604922 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,0123904 0,07585571 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,0123904 0,07566319 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,0123904 0,07547163 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,0123904 0,07528105 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,0123904 0,07509142 ! response to food GO:0032094 6 5 0,000 0,0123904 0,07490275 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,0123904 0,07471503 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,0123904 0,07452824 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0123904 0,07434238 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,0123904 0,07415745 ! forebrain neuron development GO:0021884 13 5 0,000 0,0123904 0,07397344 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,0123904 0,07379033 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,0123904 0,07360814 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,0123904 0,07342684 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0123904 0,07324643 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,0123904 0,0730669 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,0123904 0,07288825 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0123904 0,07271048 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,0123904 0,07253357 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,0123904 0,07235751 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,0123904 0,07218231 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,0123904 0,07200796 ! basic amino acid transport GO:0015802 11 5 0,000 0,0123904 0,07183445 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0123904 0,07166177 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,0123904 0,07148992 ! depyrimidination GO:0045008 10 5 0,000 0,0123904 0,07131889 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,0123904 0,07114868 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,0123904 0,07097927 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,0123904 0,07081068 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,0123904 0,07064288 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,0123904 0,07047588 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,0123904 0,07030966 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0123904 0,07014422 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,0123904 0,06997957 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,0123904 0,06981568 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,0123904 0,06965256 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,0123904 0,0694902 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,0123904 0,06932859 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0123904 0,06916774 ! response to arsenic GO:0046685 10 5 0,000 0,0123904 0,06900763 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,0123904 0,06884826 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,0123904 0,06868962 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,0123904 0,06853171 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,0123904 0,06837453 ! response to cadmium ion GO:0046686 7 5 0,000 0,0123904 0,06821807 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,0123904 0,06806232 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,0123904 0,06790728 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,0123904 0,06775294 ! decidualization GO:0046697 11 5 0,000 0,0123904 0,06759931 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,0123904 0,06744637 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,0123904 0,06729412 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,0123904 0,06714256 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,0123904 0,06699167 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,0123904 0,06684147 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,0123904 0,06669194 ! neural tube patterning GO:0021532 7 5 0,000 0,0123904 0,06654307 ! embryonic cleavage GO:0040016 6 5 0,000 0,0123904 0,06639487 ! peroxisome fission GO:0016559 5 5 0,000 0,0123904 0,06624732 ! histone demethylation GO:0016577 10 5 0,000 0,0123904 0,06610043 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,0123904 0,06595419 ! mitotic recombination GO:0006312 9 5 0,000 0,0123904 0,0658086 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,0123904 0,06566365 ! metaphase plate congression GO:0051310 7 5 0,000 0,0123904 0,06551933 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0123904 0,06537565 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,0123904 0,06523259 ! enteric nervous system development GO:0048484 8 5 0,000 0,0123904 0,06509016 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,0123904 0,06494836 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,0123904 0,06480716 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,0123904 0,06466658 ! muscle cell proliferation GO:0033002 11 5 0,000 0,0123904 0,06452661 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,0123904 0,06438725 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,0123904 0,06424848 ! plasminogen activation GO:0031639 5 5 0,000 0,0123904 0,06411031 ! B cell homeostasis GO:0001782 13 5 0,000 0,0123904 0,06397274 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,0123904 0,06383575 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,0123904 0,06369935 ! metaphase GO:0051323 8 5 0,000 0,0123904 0,06356353 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,0123904 0,06342829 ! cellular response to nutrient GO:0031670 8 5 0,000 0,0123904 0,06329362 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,0123904 0,06315952 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,0123904 0,06302599 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,0123904 0,06289303 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,0123904 0,06276062 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,0123904 0,06262877 ! response to redox state GO:0051775 5 5 0,000 0,0123904 0,06249747 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,0123904 0,06236673 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,0123904 0,06223652 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,0123904 0,06210687 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,0123904 0,06197774 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0123904 0,06184916 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,0123904 0,06172111 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0123904 0,06159359 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,0123904 0,06146659 ! striatum development GO:0021756 9 5 0,000 0,0123904 0,06134011 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,0123904 0,06121416 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,0123904 0,06108872 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,0123904 0,06096379 ! glial cell migration GO:0008347 11 5 0,000 0,0123904 0,06083938 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,0123904 0,06071547 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,0123904 0,06059206 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,0123904 0,06046916 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,0123904 0,06034675 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,0123904 0,06022484 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,0123904 0,06010342 ! neuroprotection GO:0043526 6 5 0,000 0,0123904 0,05998249 ! neural plate development GO:0001840 8 5 0,000 0,0123904 0,05986204 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,0123904 0,05974207 ! regulation of sensory perception GO:0051931 7 5 0,000 0,0123904 0,05962259 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,0123904 0,05950358 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,0123904 0,05938505 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,0123904 0,05926699 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,0123904 0,0591494 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,0123904 0,05903227 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,0123904 0,0589156 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,0123904 0,0587994 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,0123904 0,05868365 ! spindle assembly GO:0051225 6 5 0,000 0,0123904 0,05856836 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,0123904 0,05845352 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,0123904 0,05833913 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,0123904 0,05822519 ! drug metabolic process GO:0017144 6 5 0,000 0,0123904 0,05811169 ! stem cell division GO:0017145 11 5 0,000 0,0123904 0,05799863 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,0123904 0,05788601 ! organ regeneration GO:0031100 7 5 0,000 0,0123904 0,05777383 ! carnitine metabolic process GO:0009437 7 5 0,000 0,0123904 0,05766208 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,0123904 0,05755076 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,0123904 0,05743988 ! viral reproduction GO:0016032 134 68 1,000 0,01253573 0,05800187 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01253573 0,05789054 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,01288932 0,05940939 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,01288932 0,0592958 ! respiratory tube development GO:0030323 150 70 1,000 0,01324723 0,06082604 ! B cell activation GO:0042113 160 71 1,000 0,01360945 0,06237018 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,01397595 0,06392804 ! respiratory system development GO:0060541 153 72 1,000 0,01397595 0,06380673 ! learning or memory GO:0007611 147 73 1,000 0,01434672 0,06537537 ! axon guidance GO:0007411 139 73 1,000 0,01434672 0,06525179 ! neurotransmitter transport GO:0006836 123 74 1,000 0,01472171 0,06683102 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01485024 0,06728752 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01485024 0,06716104 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01485024 0,06703503 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01485024 0,0669095 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01485024 0,06678443 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01485024 0,06665984 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01485024 0,0665357 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01485024 0,06641203 ! sleep GO:0030431 13 6 0,000 0,01485024 0,06628882 ! response to oxygen radical GO:0000305 11 6 0,000 0,01485024 0,06616606 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01485024 0,06604376 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01485024 0,0659219 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01485024 0,0658005 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01485024 0,06567954 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01485024 0,06555903 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01485024 0,06543896 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01485024 0,06531933 ! forebrain regionalization GO:0021871 8 6 0,000 0,01485024 0,06520013 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01485024 0,06508137 ! male meiosis GO:0007140 7 6 0,000 0,01485024 0,06496304 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01485024 0,06484514 ! response to zinc ion GO:0010043 9 6 0,000 0,01485024 0,06472767 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01485024 0,06461062 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01485024 0,06449399 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01485024 0,06437779 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01485024 0,064262 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01485024 0,06414663 ! malate metabolic process GO:0006108 11 6 0,000 0,01485024 0,06403167 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01485024 0,06391712 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01485024 0,06380299 ! protein refolding GO:0042026 15 6 0,000 0,01485024 0,06368925 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01485024 0,06357593 ! opsonization GO:0008228 8 6 0,000 0,01485024 0,063463 ! mating behavior GO:0007617 7 6 0,000 0,01485024 0,06335048 ! neuron remodeling GO:0016322 15 6 0,000 0,01485024 0,06323836 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01485024 0,06312663 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01485024 0,06301529 ! equilibrioception GO:0050957 14 6 0,000 0,01485024 0,06290435 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01485024 0,0627938 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01485024 0,06268363 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01485024 0,06257386 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01485024 0,06246446 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01485024 0,06235545 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01485024 0,06224681 ! toxin metabolic process GO:0009404 11 6 0,000 0,01485024 0,06213856 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01485024 0,06203068 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01485024 0,06192317 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01485024 0,06181604 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01485024 0,06170928 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01485024 0,06160288 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01485024 0,06149685 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01485024 0,06139119 ! thymic T cell selection GO:0045061 12 6 0,000 0,01485024 0,06128589 ! protein lipoylation GO:0009249 10 6 0,000 0,01485024 0,06118094 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01485024 0,06107636 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01485024 0,06097214 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01485024 0,06086827 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01485024 0,06076475 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01485024 0,06066158 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01485024 0,06055877 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01485024 0,0604563 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01485024 0,06035418 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01485024 0,0602524 ! hyperosmotic response GO:0006972 9 6 0,000 0,01485024 0,06015096 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01485024 0,06004987 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01485024 0,05994911 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01485024 0,0598487 ! urea metabolic process GO:0019627 7 6 0,000 0,01485024 0,05974861 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01485024 0,05964887 ! neutrophil activation GO:0042119 8 6 0,000 0,01485024 0,05954945 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01485024 0,05945037 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01485024 0,05935161 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01485024 0,05925319 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01485024 0,05915509 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01485024 0,05905731 ! neuron apoptosis GO:0051402 9 6 0,000 0,01485024 0,05895985 ! nucleoside salvage GO:0043174 9 6 0,000 0,01485024 0,05886272 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01485024 0,05876591 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01485024 0,05866941 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01485024 0,05857323 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01485024 0,05847737 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01485024 0,05838182 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01485024 0,05828658 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01485024 0,05819165 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01485024 0,05809703 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01485024 0,05800271 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01485024 0,05790871 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01485024 0,057815 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01485024 0,0577216 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01485024 0,0576285 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01485024 0,0575357 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01485024 0,0574432 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01485024 0,057351 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01485024 0,05725909 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01485024 0,05716747 ! response to UV-C GO:0010225 11 6 0,000 0,01485024 0,05707615 ! astrocyte development GO:0014002 15 6 0,000 0,01485024 0,05698512 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01485024 0,05689438 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01485024 0,05680393 ! interaction with symbiont GO:0051702 13 6 0,000 0,01485024 0,05671376 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01485024 0,05662389 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01485024 0,05653429 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01485024 0,05644498 ! response to copper ion GO:0046688 10 6 0,000 0,01485024 0,05635595 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01485024 0,0562672 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01485024 0,05617873 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01485024 0,05609054 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01485024 0,05600262 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01485024 0,05591498 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01485024 0,05582761 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01485024 0,05574052 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01485024 0,05565369 ! hair follicle maturation GO:0048820 7 6 0,000 0,01485024 0,05556714 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01485024 0,05548086 ! Schwann cell development GO:0014044 15 6 0,000 0,01485024 0,05539484 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01485024 0,05530909 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01485024 0,0552236 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01485024 0,05513838 ! subpallium development GO:0021544 10 6 0,000 0,01485024 0,05505342 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01485024 0,05496873 ! histone ubiquitination GO:0016574 8 6 0,000 0,01485024 0,05488429 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01485024 0,05480011 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01485024 0,05471619 ! G2 phase GO:0051319 16 6 0,000 0,01485024 0,05463253 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01485024 0,05454912 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01485024 0,05446596 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01485024 0,05438306 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01485024 0,05430041 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01485024 0,05421801 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01485024 0,05413587 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01485024 0,05405397 ! receptor internalization GO:0031623 10 6 0,000 0,01485024 0,05397231 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01485024 0,05389091 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01485024 0,05380975 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01485024 0,05372883 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01485024 0,05364816 ! protein deubiquitination GO:0016579 14 6 0,000 0,01485024 0,05356772 ! protein destabilization GO:0031648 9 6 0,000 0,01485024 0,05348753 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01485024 0,05340758 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01485024 0,05332787 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01485024 0,05324839 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01485024 0,05316915 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01485024 0,05309015 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01485024 0,05301138 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01485024 0,05293285 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01485024 0,05285454 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01485024 0,05277647 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01485024 0,05269863 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01485024 0,05262102 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01485024 0,05254363 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01485024 0,05246648 ! catecholamine transport GO:0051937 9 6 0,000 0,01485024 0,05238955 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01485024 0,05231284 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01485024 0,05223636 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01485024 0,0521601 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01485024 0,05208407 ! maternal placenta development GO:0001893 12 6 0,000 0,01485024 0,05200826 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01485024 0,05193266 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01485024 0,05185729 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01485024 0,05178213 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01485024 0,0517072 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01485024 0,05163247 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01485024 0,05155797 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01485024 0,05148368 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,01510092 0,05227744 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,01510092 0,05220232 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,01510092 0,05212743 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,01587189 0,05471027 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,01665944 0,0573428 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,01665944 0,05726088 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,01705938 0,05855187 ! response to metal ion GO:0010038 140 80 1,000 0,01705938 0,05846847 ! protein import into nucleus GO:0006606 158 80 1,000 0,01705938 0,0583853 ! tRNA transcription GO:0009304 14 7 0,000 0,01730403 0,0591385 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01730403 0,05905461 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01730403 0,05897097 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01730403 0,05888756 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01730403 0,05880438 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01730403 0,05872144 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01730403 0,05863874 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01730403 0,05855626 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01730403 0,05847402 ! prostate gland development GO:0030850 13 7 0,000 0,01730403 0,05839201 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01730403 0,05831023 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01730403 0,05822868 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01730403 0,05814735 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01730403 0,05806625 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01730403 0,05798538 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01730403 0,05790473 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01730403 0,05782431 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01730403 0,05774411 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01730403 0,05766413 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01730403 0,05758438 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01730403 0,05750484 ! glycolipid transport GO:0046836 10 7 0,000 0,01730403 0,05742552 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01730403 0,05734642 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01730403 0,05726754 ! neuron adhesion GO:0007158 12 7 0,000 0,01730403 0,05718888 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01730403 0,05711043 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01730403 0,0570322 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01730403 0,05695418 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01730403 0,05687637 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01730403 0,05679878 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01730403 0,05672139 ! mRNA stabilization GO:0048255 18 7 0,000 0,01730403 0,05664422 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01730403 0,05656726 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01730403 0,05649051 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01730403 0,05641396 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01730403 0,05633762 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01730403 0,05626149 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01730403 0,05618556 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01730403 0,05610984 ! lipoprotein transport GO:0042953 14 7 0,000 0,01730403 0,05603432 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01730403 0,05595901 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01730403 0,0558839 ! rhythmic behavior GO:0007622 15 7 0,000 0,01730403 0,05580899 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01730403 0,05573427 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01730403 0,05565976 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01730403 0,05558545 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01730403 0,05551134 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01730403 0,05543742 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01730403 0,0553637 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01730403 0,05529018 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01730403 0,05521685 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01730403 0,05514371 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01730403 0,05507077 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01730403 0,05499802 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01730403 0,05492547 ! spinal cord patterning GO:0021511 13 7 0,000 0,01730403 0,0548531 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01730403 0,05478093 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01730403 0,05470894 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01730403 0,05463714 ! adrenal gland development GO:0030325 17 7 0,000 0,01730403 0,05456554 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01730403 0,05449411 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01730403 0,05442288 ! ovulation GO:0030728 9 7 0,000 0,01730403 0,05435183 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01730403 0,05428097 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01730403 0,05421029 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01730403 0,0541398 ! microtubule nucleation GO:0007020 20 7 0,000 0,01730403 0,05406948 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01730403 0,05399936 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01730403 0,05392941 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01730403 0,05385964 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01730403 0,05379006 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01730403 0,05372065 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01730403 0,05365142 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01730403 0,05358237 ! galactose metabolic process GO:0006012 13 7 0,000 0,01730403 0,0535135 ! vesicle fusion GO:0006906 17 7 0,000 0,01730403 0,05344481 ! response to dietary excess GO:0002021 8 7 0,000 0,01730403 0,05337629 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01730403 0,05330794 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01730403 0,05323977 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01730403 0,05317178 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01730403 0,05310396 ! organ growth GO:0035265 15 7 0,000 0,01730403 0,05303631 ! purine salvage GO:0043101 10 7 0,000 0,01730403 0,05296883 ! nucleoside transport GO:0015858 8 7 0,000 0,01730403 0,05290153 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01730403 0,0528344 ! parturition GO:0007567 14 7 0,000 0,01730403 0,05276743 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01730403 0,05270064 ! rRNA modification GO:0000154 14 7 0,000 0,01730403 0,05263401 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01730403 0,05256755 ! spindle checkpoint GO:0031577 15 7 0,000 0,01730403 0,05250127 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01730403 0,05243514 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01730403 0,05236919 ! macrophage differentiation GO:0030225 11 7 0,000 0,01730403 0,0523034 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01730403 0,05223777 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01730403 0,05217231 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01730403 0,05210701 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01730403 0,05204188 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01730403 0,05197691 ! fibrinolysis GO:0042730 10 7 0,000 0,01730403 0,0519121 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01730403 0,05184745 ! eating behavior GO:0042755 7 7 0,000 0,01730403 0,05178296 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01730403 0,05171864 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01730403 0,05165447 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01730403 0,05159046 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01730403 0,05152661 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01730403 0,05146292 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01730403 0,05139939 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01730403 0,05133601 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01730403 0,05127279 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01730403 0,05120972 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01730403 0,05114681 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01730403 0,05108405 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01730403 0,05102145 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01730403 0,050959 ! regulation of meiosis GO:0040020 12 7 0,000 0,01730403 0,0508967 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01730403 0,05083456 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01730403 0,05077257 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01730403 0,05071072 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01730403 0,05064903 ! transcription termination GO:0006353 13 7 0,000 0,01730403 0,05058749 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01730403 0,0505261 ! anaphase GO:0051322 17 7 0,000 0,01730403 0,05046485 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01730403 0,05040376 ! axonal fasciculation GO:0007413 18 7 0,000 0,01730403 0,05034281 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01730403 0,05028201 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01730403 0,05022136 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01730403 0,05016085 ! diuresis GO:0030146 12 7 0,000 0,01730403 0,05010049 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01730403 0,05004027 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01730403 0,0499802 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01730403 0,04992027 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01730403 0,04986048 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01730403 0,04980084 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01730403 0,04974134 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01730403 0,04968198 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01730403 0,04962277 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01730403 0,04956369 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01730403 0,04950476 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01730403 0,04944597 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01730403 0,04938731 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01730403 0,0493288 ! lymph node development GO:0048535 10 7 0,000 0,01730403 0,04927042 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01730403 0,04921218 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01730403 0,04915408 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01730403 0,04909611 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01730403 0,04903828 ! adult feeding behavior GO:0008343 9 7 0,000 0,01730403 0,04898059 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01730403 0,04892304 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01730403 0,04886561 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01730403 0,04880833 ! muscle adaptation GO:0043500 14 7 0,000 0,01730403 0,04875117 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01730403 0,04869416 ! retina homeostasis GO:0001895 12 7 0,000 0,01730403 0,04863727 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01730403 0,04858052 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01730403 0,0485239 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01730403 0,04846741 ! protein prenylation GO:0018342 18 7 0,000 0,01730403 0,04841105 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01730403 0,04835482 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01730403 0,04829873 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01730403 0,04824276 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,01746339 0,0486307 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 0,01746339 0,04857448 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,01746339 0,04851839 ! nuclear import GO:0051170 161 81 1,000 0,01746339 0,04846243 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,01787146 0,04953772 ! response to drug GO:0042493 143 82 1,000 0,01787146 0,04948072 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,01787146 0,04942384 ! response to oxygen levels GO:0070482 176 83 1,000 0,01828357 0,05050547 ! regulation of lyase activity GO:0051339 160 83 1,000 0,01828357 0,05044755 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,01869969 0,05153659 ! negative regulation of transport GO:0051051 153 84 1,000 0,01869969 0,05147763 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,01911979 0,05257397 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 0,01954387 0,05367871 ! mitochondrion organization GO:0007005 148 86 1,000 0,01954387 0,0536175 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,0197518 0,05412622 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,0197518 0,05406465 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,0197518 0,05400321 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,0197518 0,05394191 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,0197518 0,05388075 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0197518 0,05381973 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0197518 0,05375885 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,0197518 0,05369811 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,0197518 0,0536375 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,0197518 0,05357703 ! meiotic prophase I GO:0007128 13 8 0,000 0,0197518 0,0535167 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0197518 0,0534565 ! oligopeptide transport GO:0006857 15 8 0,000 0,0197518 0,05339643 ! UTP metabolic process GO:0046051 8 8 0,000 0,0197518 0,0533365 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,0197518 0,05327671 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,0197518 0,05321705 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,0197518 0,05315752 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,0197518 0,05309813 ! succinate metabolic process GO:0006105 14 8 0,000 0,0197518 0,05303887 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0197518 0,05297974 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,0197518 0,05292074 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,0197518 0,05286187 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,0197518 0,05280314 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,0197518 0,05274453 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0197518 0,05268606 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0197518 0,05262771 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,0197518 0,0525695 ! reflex GO:0060004 16 8 0,000 0,0197518 0,05251141 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,0197518 0,05245345 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,0197518 0,05239562 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,0197518 0,05233791 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,0197518 0,05228034 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,0197518 0,05222289 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,0197518 0,05216556 ! pigment granule organization GO:0048753 16 8 0,000 0,0197518 0,05210836 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,0197518 0,05205129 ! astrocyte differentiation GO:0048708 18 8 0,000 0,0197518 0,05199434 ! histidine metabolic process GO:0006547 16 8 0,000 0,0197518 0,05193751 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0197518 0,05188081 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,0197518 0,05182424 ! glycine catabolic process GO:0006546 13 8 0,000 0,0197518 0,05176778 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,0197518 0,05171145 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,0197518 0,05165525 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,0197518 0,05159916 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,0197518 0,05154319 ! melanin metabolic process GO:0006582 15 8 0,000 0,0197518 0,05148735 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,0197518 0,05143163 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0197518 0,05137603 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,0197518 0,05132055 ! macrophage activation GO:0042116 12 8 0,000 0,0197518 0,05126518 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0197518 0,05120994 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,0197518 0,05115482 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,0197518 0,05109981 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0197518 0,05104493 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,0197518 0,05099016 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,0197518 0,0509355 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,0197518 0,05088097 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,0197518 0,05082655 ! osteoblast development GO:0002076 16 8 0,000 0,0197518 0,05077225 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,0197518 0,05071806 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,0197518 0,05066399 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,0197518 0,05061004 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,0197518 0,0505562 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,0197518 0,05050247 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0197518 0,05044886 ! response to UV-B GO:0010224 16 8 0,000 0,0197518 0,05039536 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,0197518 0,05034198 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0197518 0,0502887 ! intermediate filament organization GO:0045109 12 8 0,000 0,0197518 0,05023554 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,0197518 0,0501825 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,0197518 0,05012956 ! cellular extravasation GO:0045123 12 8 0,000 0,0197518 0,05007674 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,0197518 0,05002403 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,0197518 0,04997143 ! response to antibiotic GO:0046677 11 8 0,000 0,0197518 0,04991893 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,0197518 0,04986655 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,0197518 0,04981428 ! DNA topological change GO:0006265 12 8 0,000 0,0197518 0,04976212 ! response to tropane GO:0014073 15 8 0,000 0,0197518 0,04971007 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,0197518 0,04965812 ! melanosome transport GO:0032402 13 8 0,000 0,0197518 0,04960629 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,0197518 0,04955456 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0197518 0,04950294 ! mast cell activation GO:0045576 14 8 0,000 0,0197518 0,04945143 ! multicellular organismal aging GO:0010259 18 8 0,000 0,0197518 0,04940003 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,0197518 0,04934873 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,0197518 0,04929754 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,0197518 0,04924645 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0197518 0,04919547 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0197518 0,0491446 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,0197518 0,04909383 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,0197518 0,04904316 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0197518 0,0489926 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,0197518 0,04894215 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,0197518 0,0488918 ! intracellular lipid transport GO:0032365 13 8 0,000 0,0197518 0,04884155 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0197518 0,0487914 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,0197518 0,04874136 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,0197518 0,04869142 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,0197518 0,04864158 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0197518 0,04859185 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,0197518 0,04854221 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,0197518 0,04849268 ! hormone catabolic process GO:0042447 17 8 0,000 0,0197518 0,04844325 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0197518 0,04839392 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,0197518 0,04834469 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,0197518 0,04829555 ! ATP catabolic process GO:0006200 11 8 0,000 0,0197518 0,04824652 ! blastocyst growth GO:0001832 19 8 0,000 0,0197518 0,04819759 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0197518 0,04814876 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0197518 0,04810003 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,0197518 0,04805139 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0197518 0,04800285 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0197518 0,04795442 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,0197518 0,04790607 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,0197518 0,04785783 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,0197518 0,04780968 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,0197518 0,04776163 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,0197518 0,04771368 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,0197518 0,04766582 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0197518 0,04761806 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,0197518 0,0475704 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,0197518 0,04752283 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,0197518 0,04747535 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,0197518 0,04742797 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,0197518 0,04738068 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,01997189 0,04786092 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 1,000 0,01997189 0,0478133 ! gland development GO:0048732 206 88 1,000 0,02040383 0,04879883 ! ossification GO:0001503 188 90 1,000 0,02127941 0,05084237 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,02127941 0,05079193 ! bone development GO:0060348 189 91 1,000 0,021723 0,05179934 ! axon extension GO:0048675 15 9 0,000 0,02219355 0,05286898 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02219355 0,05281669 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02219355 0,0527645 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02219355 0,05271241 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02219355 0,05266043 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02219355 0,05260854 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02219355 0,05255676 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02219355 0,05250509 ! phosphate transport GO:0006817 19 9 0,000 0,02219355 0,05245351 ! reproductive behavior GO:0019098 19 9 0,000 0,02219355 0,05240203 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02219355 0,05235066 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02219355 0,05229939 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02219355 0,05224821 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02219355 0,05219714 ! GTP metabolic process GO:0046039 9 9 0,000 0,02219355 0,05214617 ! RNA methylation GO:0001510 15 9 0,000 0,02219355 0,05209529 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02219355 0,05204452 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,02219355 0,05199384 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02219355 0,05194326 ! artery development GO:0060840 24 9 0,000 0,02219355 0,05189278 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02219355 0,0518424 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02219355 0,05179212 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02219355 0,05174193 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02219355 0,05169184 ! chemosensory behavior GO:0007635 20 9 0,000 0,02219355 0,05164185 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02219355 0,05159195 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02219355 0,05154216 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02219355 0,05149245 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02219355 0,05144285 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02219355 0,05139333 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02219355 0,05134392 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02219355 0,05129459 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02219355 0,05124537 ! protein targeting to ER GO:0045047 22 9 0,000 0,02219355 0,05119624 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02219355 0,0511472 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02219355 0,05109825 ! T cell selection GO:0045058 23 9 0,000 0,02219355 0,0510494 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02219355 0,05100064 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02219355 0,05095198 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02219355 0,05090341 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02219355 0,05085493 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02219355 0,05080654 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02219355 0,05075824 ! mannose metabolic process GO:0006013 13 9 0,000 0,02219355 0,05071004 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02219355 0,05066193 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02219355 0,05061391 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02219355 0,05056598 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02219355 0,05051814 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02219355 0,05047039 ! ruffle organization GO:0031529 15 9 0,000 0,02219355 0,05042273 ! retinol metabolic process GO:0042572 18 9 0,000 0,02219355 0,05037516 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02219355 0,05032768 ! behavioral fear response GO:0001662 22 9 0,000 0,02219355 0,05028029 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02219355 0,05023299 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02219355 0,05018578 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02219355 0,05013866 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,02219355 0,05009163 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02219355 0,05004468 ! segment specification GO:0007379 13 9 0,000 0,02219355 0,04999782 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02219355 0,04995105 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02219355 0,04990437 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02219355 0,04985777 ! response to amine stimulus GO:0014075 13 9 0,000 0,02219355 0,04981126 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02219355 0,04976484 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02219355 0,0497185 ! erythrocyte development GO:0048821 15 9 0,000 0,02219355 0,04967225 ! gas homeostasis GO:0033483 16 9 0,000 0,02219355 0,04962609 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02219355 0,04958001 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02219355 0,04953402 ! renal water homeostasis GO:0003091 14 9 0,000 0,02219355 0,04948811 ! postreplication repair GO:0006301 22 9 0,000 0,02219355 0,04944229 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02219355 0,04939655 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02219355 0,0493509 ! icosanoid secretion GO:0032309 15 9 0,000 0,02219355 0,04930533 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02219355 0,04925985 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02219355 0,04921445 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02219355 0,04916913 ! regulation of cell division GO:0051302 15 9 0,000 0,02219355 0,04912389 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02219355 0,04907874 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02219355 0,04903368 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02219355 0,04898869 ! sterol catabolic process GO:0016127 11 9 0,000 0,02219355 0,04894379 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02219355 0,04889897 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02219355 0,04885423 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02219355 0,04880957 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02219355 0,048765 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02219355 0,0487205 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02219355 0,04867609 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02219355 0,04863176 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02219355 0,04858751 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02219355 0,04854334 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02219355 0,04849925 ! purine base metabolic process GO:0006144 21 9 0,000 0,02219355 0,04845524 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02219355 0,04841131 ! pigment granule transport GO:0051904 17 9 0,000 0,02219355 0,04836746 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02219355 0,04832369 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02219355 0,04827999 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02219355 0,04823638 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02219355 0,04819285 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02219355 0,04814939 ! mitochondrion localization GO:0051646 15 9 0,000 0,02219355 0,04810601 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,02262167 0,04898987 ! regulation of membrane potential GO:0042391 164 93 1,000 0,02262167 0,04894581 ! regulation of T cell activation GO:0050863 158 94 1,000 0,02307671 0,04988551 ! detection of stimulus GO:0051606 151 96 1,000 0,02399809 0,05183071 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02462929 0,05314626 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02462929 0,05309864 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02462929 0,0530511 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02462929 0,05300365 ! synapsis GO:0007129 13 10 0,000 0,02462929 0,05295628 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02462929 0,052909 ! N-glycan processing GO:0006491 20 10 0,000 0,02462929 0,0528618 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02462929 0,05281469 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02462929 0,05276766 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02462929 0,05272071 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02462929 0,05267385 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02462929 0,05262707 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02462929 0,05258037 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02462929 0,05253376 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02462929 0,05248723 ! androgen metabolic process GO:0008209 17 10 0,000 0,02462929 0,05244078 ! phospholipid efflux GO:0033700 16 10 0,000 0,02462929 0,05239441 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02462929 0,05234813 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02462929 0,05230193 ! lung alveolus development GO:0048286 26 10 0,000 0,02462929 0,0522558 ! pathogenesis GO:0009405 13 10 0,000 0,02462929 0,05220976 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02462929 0,0521638 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02462929 0,05211793 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02462929 0,05207213 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02462929 0,05202641 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02462929 0,05198077 ! endoderm development GO:0007492 16 10 0,000 0,02462929 0,05193522 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02462929 0,05188974 ! arginine catabolic process GO:0006527 13 10 0,000 0,02462929 0,05184434 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02462929 0,05179902 ! proline metabolic process GO:0006560 13 10 0,000 0,02462929 0,05175378 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02462929 0,05170862 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02462929 0,05166354 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02462929 0,05161854 ! V(D)J recombination GO:0033151 28 10 0,000 0,02462929 0,05157361 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02462929 0,05152877 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02462929 0,051484 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02462929 0,05143931 ! B cell proliferation GO:0042100 18 10 0,000 0,02462929 0,05139469 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02462929 0,05135016 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02462929 0,0513057 ! multicellular organism growth GO:0035264 18 10 0,000 0,02462929 0,05126132 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02462929 0,05121701 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02462929 0,05117278 ! epithelial cell development GO:0002064 20 10 0,000 0,02462929 0,05112863 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02462929 0,05108455 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02462929 0,05104055 ! macroautophagy GO:0016236 17 10 0,000 0,02462929 0,05099663 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02462929 0,05095278 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02462929 0,050909 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02462929 0,05086531 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02462929 0,05082168 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02462929 0,05077813 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02462929 0,05073466 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02462929 0,05069126 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02462929 0,05064793 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02462929 0,05060468 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02462929 0,0505615 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02462929 0,0505184 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02462929 0,05047537 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02462929 0,05043241 ! response to dsRNA GO:0043331 20 10 0,000 0,02462929 0,05038953 ! DNA ligation GO:0006266 19 10 0,000 0,02462929 0,05034671 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02462929 0,05030397 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02462929 0,05026131 ! melanosome localization GO:0032400 16 10 0,000 0,02462929 0,05021871 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02462929 0,05017619 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02462929 0,05013374 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02462929 0,05009136 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02462929 0,05004906 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02462929 0,05000682 ! mRNA cleavage GO:0006379 17 10 0,000 0,02462929 0,04996466 ! protein sumoylation GO:0016925 15 10 0,000 0,02462929 0,04992256 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02462929 0,04988054 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02462929 0,04983859 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02462929 0,04979671 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02462929 0,0497549 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02462929 0,04971316 ! salivary gland development GO:0007431 27 10 0,000 0,02462929 0,04967148 ! prophase GO:0051324 15 10 0,000 0,02462929 0,04962988 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02462929 0,04958835 ! apical protein localization GO:0045176 15 10 0,000 0,02462929 0,04954689 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02462929 0,0495055 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02462929 0,04946417 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02462929 0,04942292 ! midbrain development GO:0030901 13 10 0,000 0,02462929 0,04938173 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02462929 0,04934062 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02462929 0,04929957 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02462929 0,04925859 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02462929 0,04921768 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02462929 0,04917683 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02462929 0,04913605 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02462929 0,04909535 ! oocyte development GO:0048599 17 10 0,000 0,02462929 0,0490547 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02462929 0,04901413 ! blastocyst formation GO:0001825 17 10 0,000 0,02462929 0,04897362 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02462929 0,04893318 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02462929 0,04889281 ! activation of innate immune response GO:0002218 12 10 0,000 0,02462929 0,0488525 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02462929 0,04881226 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02462929 0,04877208 ! response to nicotine GO:0035094 20 10 0,000 0,02462929 0,04873197 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02462929 0,04869193 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02462929 0,04865196 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02462929 0,04861204 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,02540811 0,05010812 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02705905 0,0533203 ! respiratory burst GO:0045730 17 11 0,000 0,02705905 0,05327667 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02705905 0,0532331 ! neuron fate specification GO:0048665 17 11 0,000 0,02705905 0,05318961 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02705905 0,05314619 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02705905 0,05310284 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02705905 0,05305956 ! thyroid gland development GO:0030878 26 11 0,000 0,02705905 0,05301636 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02705905 0,05297322 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02705905 0,05293015 ! response to pain GO:0048265 24 11 0,000 0,02705905 0,05288715 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02705905 0,05284423 ! T cell proliferation GO:0042098 26 11 0,000 0,02705905 0,05280137 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02705905 0,05275858 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02705905 0,05271586 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,02705905 0,05267321 ! bone resorption GO:0045453 16 11 0,000 0,02705905 0,05263063 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02705905 0,05258811 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02705905 0,05254567 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02705905 0,05250329 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02705905 0,05246099 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02705905 0,05241875 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02705905 0,05237658 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02705905 0,05233447 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02705905 0,05229244 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02705905 0,05225047 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,02705905 0,05220857 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02705905 0,05216674 ! UV protection GO:0009650 19 11 0,000 0,02705905 0,05212497 ! adult heart development GO:0007512 14 11 0,000 0,02705905 0,05208327 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02705905 0,05204164 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02705905 0,05200007 ! temperature homeostasis GO:0001659 17 11 0,000 0,02705905 0,05195857 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02705905 0,05191713 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02705905 0,05187577 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02705905 0,05183446 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02705905 0,05179323 ! regulation of organ growth GO:0046620 13 11 0,000 0,02705905 0,05175206 ! pigment granule localization GO:0051875 20 11 0,000 0,02705905 0,05171095 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02705905 0,05166991 ! vasoconstriction GO:0042310 18 11 0,000 0,02705905 0,05162893 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02705905 0,05158802 ! embryonic axis specification GO:0000578 18 11 0,000 0,02705905 0,05154718 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02705905 0,0515064 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02705905 0,05146568 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02705905 0,05142503 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02705905 0,05138444 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02705905 0,05134392 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02705905 0,05130346 ! zymogen activation GO:0031638 15 11 0,000 0,02705905 0,05126306 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02705905 0,05122273 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02705905 0,05118246 ! nucleosome positioning GO:0016584 15 11 0,000 0,02705905 0,05114225 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02705905 0,05110211 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02705905 0,05106203 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02705905 0,05102201 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,02705905 0,05098206 ! acid secretion GO:0046717 18 11 0,000 0,02705905 0,05094216 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02705905 0,05090233 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02705905 0,05086257 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02705905 0,05082286 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02705905 0,05078322 ! oocyte differentiation GO:0009994 18 11 0,000 0,02705905 0,05074364 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02705905 0,05070412 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02705905 0,05066466 ! cholesterol efflux GO:0033344 19 11 0,000 0,02705905 0,05062526 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02705905 0,05058593 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02705905 0,05054665 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02705905 0,05050744 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02705905 0,05046828 ! embryonic gut development GO:0048566 15 11 0,000 0,02705905 0,05042919 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02705905 0,05039016 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02705905 0,05035119 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,02705905 0,05031228 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02705905 0,05027343 ! defense response to fungus GO:0050832 13 11 0,000 0,02705905 0,05023463 ! developmental induction GO:0031128 19 11 0,000 0,02705905 0,0501959 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,02705905 0,05015723 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02705905 0,05011862 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02705905 0,05008007 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02705905 0,05004157 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02705905 0,05000314 ! nucleus localization GO:0051647 19 11 0,000 0,02705905 0,04996476 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02705905 0,04992645 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,02948284 0,05435687 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,02948284 0,05431525 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,02948284 0,0542737 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,02948284 0,0542322 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,02948284 0,05419077 ! cartilage condensation GO:0001502 20 12 0,000 0,02948284 0,0541494 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,02948284 0,0541081 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,02948284 0,05406686 ! protein complex disassembly GO:0043241 27 12 0,000 0,02948284 0,05402568 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,02948284 0,05398457 ! hippocampus development GO:0021766 26 12 0,000 0,02948284 0,05394351 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,02948284 0,05390252 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,02948284 0,05386159 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,02948284 0,05382073 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,02948284 0,05377992 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,02948284 0,05373918 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,02948284 0,0536985 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,02948284 0,05365788 ! drug transport GO:0015893 16 12 0,000 0,02948284 0,05361732 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,02948284 0,05357683 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,02948284 0,05353639 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,02948284 0,05349602 ! polyamine metabolic process GO:0006595 17 12 0,000 0,02948284 0,0534557 ! focal adhesion formation GO:0048041 35 12 0,000 0,02948284 0,05341545 ! mitotic spindle organization GO:0007052 21 12 0,000 0,02948284 0,05337526 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,02948284 0,05333513 ! forebrain cell migration GO:0021885 21 12 0,000 0,02948284 0,05329506 ! asymmetric protein localization GO:0008105 20 12 0,000 0,02948284 0,05325505 ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,02948284 0,05321509 ! entry into host cell GO:0030260 32 12 0,000 0,02948284 0,0531752 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,02948284 0,05313537 ! monoamine transport GO:0015844 18 12 0,000 0,02948284 0,0530956 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,02948284 0,05305589 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,02948284 0,05301623 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,02948284 0,05297664 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,02948284 0,0529371 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,02948284 0,05289763 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,02948284 0,05285821 ! protein homotetramerization GO:0051289 21 12 0,000 0,02948284 0,05281885 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,02948284 0,05277955 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,02948284 0,05274031 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,02948284 0,05270113 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,02948284 0,052662 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,02948284 0,05262294 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,02948284 0,05258393 ! fucose catabolic process GO:0019317 22 12 0,000 0,02948284 0,05254498 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,02948284 0,05250608 ! histone methylation GO:0016571 26 12 0,000 0,02948284 0,05246725 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,02948284 0,05242847 ! gland morphogenesis GO:0022612 29 12 0,000 0,02948284 0,05238975 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,02948284 0,05235109 ! T cell homeostasis GO:0043029 25 12 0,000 0,02948284 0,05231248 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,02948284 0,05227393 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,02948284 0,05223543 ! spleen development GO:0048536 22 12 0,000 0,02948284 0,052197 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,02948284 0,05215862 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,02948284 0,05212029 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,02948284 0,05208203 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,02948284 0,05204382 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,02948284 0,05200566 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,02948284 0,05196756 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,02948284 0,05192952 ! response to cold GO:0009409 17 12 0,000 0,02948284 0,05189153 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,02948284 0,0518536 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,02948284 0,05181572 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03190067 0,0560241 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,03190067 0,05598324 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03190067 0,05594243 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03190067 0,05590169 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,03190067 0,055861 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,03190067 0,05582038 ! lipid localization GO:0010876 28 13 0,000 0,03190067 0,05577981 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,03190067 0,0557393 ! organelle fusion GO:0048284 32 13 0,000 0,03190067 0,05569885 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,03190067 0,05565846 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,03190067 0,05561813 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,03190067 0,05557786 ! endocrine pancreas development GO:0031018 22 13 0,000 0,03190067 0,05553764 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,03190067 0,05549748 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,03190067 0,05545738 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,03190067 0,05541734 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03190067 0,05537736 ! methionine metabolic process GO:0006555 27 13 0,000 0,03190067 0,05533743 ! plasma membrane organization GO:0007009 24 13 0,000 0,03190067 0,05529757 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,03190067 0,05525775 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,03190067 0,055218 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,03190067 0,0551783 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,03190067 0,05513866 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,03190067 0,05509908 ! cytokine metabolic process GO:0042107 22 13 0,000 0,03190067 0,05505956 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,03190067 0,05502009 ! exocrine system development GO:0035272 32 13 0,000 0,03190067 0,05498067 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,03190067 0,05494132 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,03190067 0,05490202 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,03190067 0,05486277 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,03190067 0,05482359 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,03190067 0,05478445 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,03190067 0,05474538 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,03190067 0,05470636 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,03190067 0,05466739 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,03190067 0,05462848 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03190067 0,05458963 ! ribosome assembly GO:0042255 17 13 0,000 0,03190067 0,05455083 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,03190067 0,05451209 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,03190067 0,0544734 ! chromatin silencing GO:0006342 26 13 0,000 0,03190067 0,05443477 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,03190067 0,05439619 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03190067 0,05435766 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03190067 0,05431919 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,03190067 0,05428078 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,03190067 0,05424242 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,03190067 0,05420411 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03190067 0,05416586 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,03190067 0,05412766 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,03190067 0,05408951 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,03190067 0,05405142 ! embryonic placenta development GO:0001892 23 13 0,000 0,03190067 0,05401339 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,03190067 0,0539754 ! insulin secretion GO:0030073 23 13 0,000 0,03190067 0,05393747 ! actin filament polymerization GO:0030041 24 13 0,000 0,03190067 0,05389959 ! acrosome reaction GO:0007340 18 13 0,000 0,03190067 0,05386177 ! rRNA transcription GO:0009303 25 14 0,000 0,03431256 0,05789342 ! lactation GO:0007595 26 14 0,000 0,03431256 0,05785285 ! reproductive cellular process GO:0048610 20 14 0,000 0,03431256 0,05781234 ! tRNA modification GO:0006400 20 14 0,000 0,03431256 0,05777188 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03431256 0,05773148 ! regulation of S phase GO:0033261 23 14 0,000 0,03431256 0,05769114 ! water transport GO:0006833 21 14 0,000 0,03431256 0,05765085 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,03431256 0,05761062 ! non-recombinational repair GO:0000726 25 14 0,000 0,03431256 0,05757045 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03431256 0,05753033 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03431256 0,05749027 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03431256 0,05745026 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,03431256 0,05741031 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03431256 0,05737041 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03431256 0,05733057 ! palate development GO:0060021 31 14 0,000 0,03431256 0,05729078 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,03431256 0,05725105 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03431256 0,05721138 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,03431256 0,05717176 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,03431256 0,05713219 ! arginine metabolic process GO:0006525 17 14 0,000 0,03431256 0,05709268 ! regulation of heart rate GO:0002027 24 14 0,000 0,03431256 0,05705323 ! organic alcohol transport GO:0015850 29 14 0,000 0,03431256 0,05701383 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,03431256 0,05697448 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,03431256 0,05693519 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03431256 0,05689595 ! neutral amino acid transport GO:0015804 26 14 0,000 0,03431256 0,05685676 ! L-amino acid transport GO:0015807 30 14 0,000 0,03431256 0,05681763 ! bone mineralization GO:0030282 17 14 0,000 0,03431256 0,05677856 ! stem cell development GO:0048864 43 14 0,000 0,03431256 0,05673953 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,03431256 0,05670056 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,03431256 0,05666165 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03431256 0,05662279 ! cerebellum development GO:0021549 21 14 0,000 0,03431256 0,05658398 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,03431256 0,05654522 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,03431256 0,05650652 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,03431256 0,05646787 ! cofactor transport GO:0051181 26 14 0,000 0,03431256 0,05642927 ! NADP metabolic process GO:0006739 24 14 0,000 0,03431256 0,05639072 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03431256 0,05635223 ! intestinal absorption GO:0050892 25 14 0,000 0,03431256 0,05631379 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,03431256 0,05627541 ! oxygen transport GO:0015671 21 14 0,000 0,03431256 0,05623707 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03431256 0,05619879 ! male genitalia development GO:0030539 24 14 0,000 0,03431256 0,05616056 ! regulation of RNA stability GO:0043487 32 14 0,000 0,03431256 0,05612238 ! regulation of axon extension GO:0030516 37 14 0,000 0,03431256 0,05608425 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03431256 0,05604618 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03671852 0,05993538 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03671852 0,05989475 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,03671852 0,05985417 ! superoxide anion generation GO:0042554 20 15 0,000 0,03671852 0,05981365 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,03671852 0,05977318 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,03671852 0,05973276 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,03671852 0,0596924 ! copper ion transport GO:0006825 20 15 0,000 0,03671852 0,0596521 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,03671852 0,05961185 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,03671852 0,05957165 ! sulfate transport GO:0008272 23 15 0,000 0,03671852 0,05953151 ! response to cAMP GO:0051591 22 15 0,000 0,03671852 0,05949142 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,03671852 0,05945138 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,03671852 0,0594114 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,03671852 0,05937148 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,03671852 0,0593316 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,03671852 0,05929178 ! response to hexose stimulus GO:0009746 22 15 0,000 0,03671852 0,05925202 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,03671852 0,0592123 ! pituitary gland development GO:0021983 29 15 0,000 0,03671852 0,05917264 ! vesicle coating GO:0006901 33 15 0,000 0,03671852 0,05913304 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,03671852 0,05909348 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,03671852 0,05905398 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,03671852 0,05901453 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,03671852 0,05897514 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,03671852 0,05893579 ! regulation of vasodilation GO:0042312 26 15 0,000 0,03671852 0,0588965 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,03671852 0,05885727 ! histone deacetylation GO:0016575 20 15 0,000 0,03671852 0,05881808 ! mRNA splice site selection GO:0006376 38 15 0,000 0,03671852 0,05877895 ! tissue regeneration GO:0042246 26 15 0,000 0,03671852 0,05873986 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03671852 0,05870083 ! water homeostasis GO:0030104 27 15 0,000 0,03671852 0,05866186 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03671852 0,05862293 ! muscle maintenance GO:0046716 26 15 0,000 0,03671852 0,05858406 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,03671852 0,05854523 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,03671852 0,05850646 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03671852 0,05846774 ! heme biosynthetic process GO:0006783 29 15 0,000 0,03671852 0,05842907 ! cell killing GO:0001906 29 15 0,000 0,03671852 0,05839045 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,03671852 0,05835189 ! detection of bacterium GO:0016045 18 15 0,000 0,03671852 0,05831337 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,03671852 0,05827491 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,03671852 0,05823649 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,03671852 0,05819813 ! peptide hormone processing GO:0016486 23 15 0,000 0,03671852 0,05815981 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,03911856 0,06192057 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,03911856 0,06187986 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,03911856 0,0618392 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,03911856 0,0617986 ! bone remodeling GO:0046849 27 16 0,000 0,03911856 0,06175805 ! filopodium assembly GO:0046847 32 16 0,000 0,03911856 0,06171755 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,03911856 0,0616771 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,03911856 0,06163671 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,03911856 0,06159637 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,03911856 0,06155609 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,03911856 0,06151586 ! startle response GO:0001964 28 16 0,000 0,03911856 0,06147568 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,03911856 0,06143555 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,03911856 0,06139547 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,03911856 0,06135545 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,03911856 0,06131548 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,03911856 0,06127556 ! protein polyubiquitination GO:0000209 34 16 0,000 0,03911856 0,06123569 ! glutamate metabolic process GO:0006536 22 16 0,000 0,03911856 0,06119588 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,03911856 0,06115611 ! response to osmotic stress GO:0006970 25 16 0,000 0,03911856 0,0611164 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,03911856 0,06107674 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,03911856 0,06103713 ! fructose metabolic process GO:0006000 25 16 0,000 0,03911856 0,06099758 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,03911856 0,06095807 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,03911856 0,06091862 ! intermediate filament-based process GO:0045103 32 16 0,000 0,03911856 0,06087921 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,03911856 0,06083986 ! negative regulation of immune response GO:0050777 35 16 0,000 0,03911856 0,06080056 ! axon cargo transport GO:0008088 43 16 0,000 0,03911856 0,0607613 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,03911856 0,0607221 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,03911856 0,06068295 ! DNA replication initiation GO:0006270 27 16 0,000 0,03911856 0,06064385 ! neuron recognition GO:0008038 35 16 0,000 0,03911856 0,0606048 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,03911856 0,0605658 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,03911856 0,06052686 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,03911856 0,06048796 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,03911856 0,06044911 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,03911856 0,06041031 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,03911856 0,06037156 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,03911856 0,06033286 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,03911856 0,06029421 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,03911856 0,06025561 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,03911856 0,06021706 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,03911856 0,06017856 ! defense response to virus GO:0051607 37 16 0,000 0,03911856 0,0601401 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,04151271 0,06378006 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,04151271 0,06373936 ! metencephalon development GO:0022037 30 17 0,000 0,04151271 0,06369871 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,04151271 0,06365811 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,04151271 0,06361756 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,04151271 0,06357707 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,04151271 0,06353662 ! endothelial cell migration GO:0043542 28 17 0,000 0,04151271 0,06349623 ! inositol metabolic process GO:0006020 28 17 0,000 0,04151271 0,06345589 ! gene silencing by RNA GO:0031047 36 17 0,000 0,04151271 0,0634156 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,04151271 0,06337536 ! glial cell development GO:0021782 27 17 0,000 0,04151271 0,06333517 ! limbic system development GO:0021761 36 17 0,000 0,04151271 0,06329504 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,04151271 0,06325495 ! adult walking behavior GO:0007628 33 17 0,000 0,04151271 0,06321492 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,04151271 0,06317493 ! heart looping GO:0001947 30 17 0,000 0,04151271 0,063135 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,04151271 0,06309512 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,04151271 0,06305528 ! myoblast differentiation GO:0045445 45 17 0,000 0,04151271 0,0630155 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,04151271 0,06297577 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,04151271 0,06293609 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,04151271 0,06289645 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,04151271 0,06285687 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,04151271 0,06281734 ! glycine metabolic process GO:0006544 28 17 0,000 0,04151271 0,06277786 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,04151271 0,06273842 ! NAD metabolic process GO:0019674 29 17 0,000 0,04151271 0,06269904 ! membrane budding GO:0006900 37 17 0,000 0,04151271 0,0626597 ! DNA integration GO:0015074 29 17 0,000 0,04151271 0,06262042 ! regulation of protein binding GO:0043393 33 17 0,000 0,04151271 0,06258118 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,04151271 0,062542 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,04151271 0,06250286 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,04151271 0,06246377 ! genitalia development GO:0048806 30 17 0,000 0,04151271 0,06242473 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,04151271 0,06238574 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,04151271 0,0623468 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,04151271 0,0623079 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,04151271 0,06226906 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,04151271 0,06223026 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,04151271 0,06219151 ! steroid catabolic process GO:0006706 31 17 0,000 0,04151271 0,06215281 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,04151271 0,06211416 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,04151271 0,06207556 ! gas transport GO:0015669 25 17 0,000 0,04151271 0,062037 ! organic cation transport GO:0015695 31 17 0,000 0,04151271 0,06199849 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,04151271 0,06196003 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,04151271 0,06192162 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,04151271 0,06188325 ! microspike assembly GO:0030035 36 17 0,000 0,04151271 0,06184493 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,04151271 0,06180666 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,04151271 0,06176844 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,04390096 0,06528165 ! neuron maturation GO:0042551 42 18 0,000 0,04390096 0,06524133 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,04390096 0,06520106 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,04390096 0,06516084 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,04390096 0,06512066 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,04390096 0,06508054 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,04390096 0,06504047 ! memory GO:0007613 31 18 0,000 0,04390096 0,06500044 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04390096 0,06496047 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,04390096 0,06492054 ! patterning of blood vessels GO:0001569 39 18 0,000 0,04390096 0,06488066 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,04390096 0,06484083 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,04390096 0,06480105 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,04390096 0,06476132 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04390096 0,06472164 ! response to retinoic acid GO:0032526 26 18 0,000 0,04390096 0,06468201 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,04390096 0,06464242 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,04390096 0,06460288 ! response to fungus GO:0009620 21 18 0,000 0,04390096 0,0645634 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,04390096 0,06452396 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,04390096 0,06448456 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,04390096 0,06444522 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,04390096 0,06440592 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,04390096 0,06436668 ! vitamin transport GO:0051180 27 18 0,000 0,04390096 0,06432748 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,04390096 0,06428832 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,04390096 0,06424922 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,04390096 0,06421016 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,04390096 0,06417115 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,04390096 0,06413219 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,04390096 0,06409327 ! protein secretion GO:0009306 39 19 0,000 0,04628335 0,06753047 ! positive regulation of translation GO:0045727 30 19 0,000 0,04628335 0,06748954 ! negative regulation of defense response GO:0031348 25 19 0,000 0,04628335 0,06744866 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,04628335 0,06740783 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,04628335 0,06736705 ! skin development GO:0043588 36 19 0,000 0,04628335 0,06732632 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,04628335 0,06728564 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04628335 0,06724501 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,04628335 0,06720443 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,04628335 0,06716389 ! bile acid metabolic process GO:0008206 29 19 0,000 0,04628335 0,06712341 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,04628335 0,06708297 ! cerebral cortex development GO:0021987 36 19 0,000 0,04628335 0,06704259 ! pigmentation during development GO:0048066 41 19 0,000 0,04628335 0,06700225 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,04628335 0,06696196 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,04628335 0,06692172 ! heme metabolic process GO:0042168 36 19 0,000 0,04628335 0,06688152 ! actin filament bundle formation GO:0051017 42 19 0,000 0,04628335 0,06684138 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,04628335 0,06680128 ! plasma membrane fusion GO:0045026 28 19 0,000 0,04628335 0,06676123 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,04628335 0,06672123 ! peptide cross-linking GO:0018149 37 19 0,000 0,04628335 0,06668128 ! protein export from nucleus GO:0006611 36 19 0,000 0,04628335 0,06664137 ! heart process GO:0003015 30 19 0,000 0,04628335 0,06660152 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,04628335 0,06656171 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,04628335 0,06652195 ! visual learning GO:0008542 36 19 0,000 0,04628335 0,06648223 ! cellular pigmentation GO:0033059 36 19 0,000 0,04628335 0,06644256 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,04628335 0,06640294 ! cell-cell junction organization GO:0045216 35 19 0,000 0,04628335 0,06636337 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,04628335 0,06632385 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,04628335 0,06628437 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,04628335 0,06624494 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,04628335 0,06620555 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,04628335 0,06616621 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,04628335 0,06612692 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,04628335 0,06608768 ! cilium assembly GO:0042384 37 19 0,000 0,04628335 0,06604848 ! peptide hormone secretion GO:0030072 31 19 0,000 0,04628335 0,06600933 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,04865988 0,06935762 ! positive regulation of ossification GO:0045778 47 20 0,000 0,04865988 0,06931656 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,04865988 0,06927554 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,04865988 0,06923457 ! cAMP metabolic process GO:0046058 36 20 0,000 0,04865988 0,06919365 ! response to vitamin GO:0033273 31 20 0,000 0,04865988 0,06915278 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,04865988 0,06911196 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,04865988 0,06907119 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,04865988 0,06903046 ! response to alkaloid GO:0043279 38 20 0,000 0,04865988 0,06898978 ! retinoid metabolic process GO:0001523 32 20 0,000 0,04865988 0,06894915 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,04865988 0,06890857 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,04865988 0,06886804 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,04865988 0,06882755 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,04865988 0,06878711 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,04865988 0,06874672 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,04865988 0,06870638 ! body fluid secretion GO:0007589 31 20 0,000 0,04865988 0,06866608 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,04865988 0,06862583 ! peptide secretion GO:0002790 35 20 0,000 0,04865988 0,06858563 ! stem cell differentiation GO:0048863 53 20 0,000 0,04865988 0,06854547 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,04865988 0,06850536 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,04865988 0,0684653 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,04865988 0,06842529 ! sensory perception of pain GO:0019233 30 20 0,000 0,04865988 0,06838532 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,04865988 0,0683454 ! diencephalon development GO:0021536 34 20 0,000 0,04865988 0,06830552 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,04865988 0,06826569 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,04865988 0,06822591 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,04865988 0,06818618 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,04865988 0,06814649 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,04865988 0,06810684 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,04865988 0,06806725 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,04865988 0,0680277 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,04865988 0,06798819 ! regulation of glucose import GO:0046324 29 20 0,000 0,04865988 0,06794873 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,04865988 0,06790932 ! actin filament-based movement GO:0030048 43 20 0,000 0,04865988 0,06786995 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,04865988 0,06783063 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,04865988 0,06779135 ! negative regulation of translation GO:0017148 29 20 0,000 0,04865988 0,06775212 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,04865988 0,06771293 ! regulation of cell killing GO:0031341 42 21 0,000 0,05103056 0,07097083 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,05103056 0,07092983 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,05103056 0,07088888 ! hormone secretion GO:0046879 38 21 0,000 0,05103056 0,07084797 ! glycerol metabolic process GO:0006071 34 21 0,000 0,05103056 0,07080711 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,05103056 0,0707663 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,05103056 0,07072554 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,05103056 0,07068482 ! axis specification GO:0009798 38 21 0,000 0,05103056 0,07064415 ! ovarian follicle development GO:0001541 35 21 0,000 0,05103056 0,07060353 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,05103056 0,07056295 ! smooth muscle contraction GO:0006939 46 21 0,000 0,05103056 0,07052242 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,05103056 0,07048194 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,05103056 0,0704415 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,05103056 0,07040111 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,05103056 0,07036076 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,05103056 0,07032047 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,05103056 0,07028021 ! cytolysis GO:0019835 24 21 0,000 0,05103056 0,07024001 ! vasodilation GO:0042311 39 21 0,000 0,05103056 0,07019985 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,05103056 0,07015973 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,05103056 0,07011966 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,05103056 0,07007964 ! oogenesis GO:0048477 36 21 0,000 0,05103056 0,07003966 ! DNA modification GO:0006304 34 21 0,000 0,05103056 0,06999973 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,05103056 0,06995985 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,05103056 0,06992001 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,05103056 0,06988021 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,05103056 0,06984046 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,05103056 0,06980076 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,05103056 0,0697611 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,05103056 0,06972148 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,05103056 0,06968191 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,05103056 0,06964239 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,05103056 0,06960291 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,05103056 0,06956347 ! collagen catabolic process GO:0030574 28 21 0,000 0,05103056 0,06952408 ! sperm-egg recognition GO:0035036 21 21 0,000 0,05103056 0,06948474 ! gut development GO:0048565 39 21 0,000 0,05103056 0,06944544 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,05339542 0,0726226 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,05339542 0,07258157 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,05339542 0,07254058 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,05339542 0,07249965 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,05339542 0,07245876 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,05339542 0,07241791 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,05339542 0,07237711 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,05339542 0,07233636 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,05339542 0,07229565 ! regeneration GO:0031099 41 22 0,000 0,05339542 0,07225499 ! keratinization GO:0031424 28 22 0,000 0,05339542 0,07221438 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,05339542 0,07217381 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,05339542 0,07213328 ! sensory perception of taste GO:0050909 28 22 0,000 0,05339542 0,0720928 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,05339542 0,07205237 ! vacuolar transport GO:0007034 36 22 0,000 0,05339542 0,07201198 ! lysosome organization GO:0007040 41 22 0,000 0,05339542 0,07197164 ! central nervous system neuron development GO:0021954 46 22 0,000 0,05339542 0,07193134 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,05339542 0,07189109 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,05339542 0,07185088 ! fucose metabolic process GO:0006004 39 22 0,000 0,05339542 0,07181072 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,05339542 0,0717706 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,05339542 0,07173053 ! ureteric bud development GO:0001657 43 22 0,000 0,05339542 0,0716905 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,05339542 0,07165052 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,05339542 0,07161058 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,05339542 0,07157068 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,05339542 0,07153083 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,05339542 0,07149103 ! sarcomere organization GO:0045214 30 22 0,000 0,05339542 0,07145127 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,05339542 0,07141155 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,05339542 0,07137188 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,05339542 0,07133225 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,05339542 0,07129266 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,05339542 0,07125312 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,05575446 0,07435988 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,05575446 0,07431869 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,05575446 0,07427754 ! gluconeogenesis GO:0006094 33 23 0,000 0,05575446 0,07423643 ! viral genome replication GO:0019079 41 23 0,000 0,05575446 0,07419537 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,05575446 0,07415436 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,05575446 0,07411339 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,05575446 0,07407246 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,05575446 0,07403158 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,05575446 0,07399075 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,05575446 0,07394996 ! visual behavior GO:0007632 42 23 0,000 0,05575446 0,07390922 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,05575446 0,07386852 ! response to ethanol GO:0045471 46 23 0,000 0,05575446 0,07382786 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,05575446 0,07378725 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,05575446 0,07374669 ! peroxisome organization GO:0007031 37 23 0,000 0,05575446 0,07370617 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,05575446 0,07366569 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,05575446 0,07362526 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,05575446 0,07358488 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,05575446 0,07354453 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,05575446 0,07350424 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,05575446 0,07346398 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,05575446 0,07342377 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,05575446 0,0733836 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,05575446 0,07334348 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,05575446 0,0733034 ! fatty acid transport GO:0015908 44 23 0,000 0,05575446 0,07326337 ! platelet activation GO:0030168 37 23 0,000 0,05575446 0,07322338 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,05575446 0,07318343 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,05575446 0,07314353 ! hormone transport GO:0009914 40 23 0,000 0,05575446 0,07310367 ! cell-cell recognition GO:0009988 25 23 0,000 0,05575446 0,07306385 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,05575446 0,07302408 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,05575446 0,07298435 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,05575446 0,07294466 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,05575446 0,07290502 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,0581077 0,07594086 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,0581077 0,07589963 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,0581077 0,07585845 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,0581077 0,07581731 ! vesicle docking GO:0048278 47 24 0,000 0,0581077 0,07577622 ! spinal cord development GO:0021510 47 24 0,000 0,0581077 0,07573517 ! vacuole organization GO:0007033 43 24 0,000 0,0581077 0,07569417 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,0581077 0,07565321 ! digestive system process GO:0022600 39 24 0,000 0,0581077 0,07561229 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,0581077 0,07557142 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,0581077 0,07553059 ! regulation of behavior GO:0050795 43 24 0,000 0,0581077 0,07548981 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,0581077 0,07544907 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,0581077 0,07540837 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,0581077 0,07536772 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,0581077 0,07532711 ! membrane depolarization GO:0051899 39 24 0,000 0,0581077 0,07528655 ! pallium development GO:0021543 49 24 0,000 0,0581077 0,07524603 ! pentose metabolic process GO:0019321 35 24 0,000 0,0581077 0,07520555 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,0581077 0,07516512 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,0581077 0,07512473 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,0581077 0,07508439 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,0581077 0,07504408 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,0581077 0,07500382 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,0581077 0,07496361 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,0581077 0,07492343 ! regulation of amine transport GO:0051952 40 24 0,000 0,0581077 0,0748833 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,06045515 0,07786676 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,06045515 0,07782509 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,06045515 0,07778348 ! phototransduction GO:0007602 33 25 0,000 0,06045515 0,0777419 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,06045515 0,07770037 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,06045515 0,07765889 ! sperm motility GO:0030317 31 25 0,000 0,06045515 0,07761745 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,06045515 0,07757605 ! chromosome condensation GO:0030261 45 25 0,000 0,06045515 0,0775347 ! osteoblast differentiation GO:0001649 60 25 0,000 0,06045515 0,07749339 ! neural crest cell development GO:0014032 54 25 0,000 0,06045515 0,07745213 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,06045515 0,07741091 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,06045515 0,07736973 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,06045515 0,0773286 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,06045515 0,07728751 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,06045515 0,07724647 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,06045515 0,07720547 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,06045515 0,07716451 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,06045515 0,07712359 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,06045515 0,07708272 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,06045515 0,0770419 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,06045515 0,07700111 ! telomere organization GO:0032200 43 25 0,000 0,06045515 0,07696037 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,06045515 0,07691967 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,06045515 0,07687902 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,06279683 0,07981468 ! embryonic pattern specification GO:0009880 44 26 0,000 0,06279683 0,07977254 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,06279683 0,07973044 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,06279683 0,07968839 ! initiation of viral infection GO:0019059 57 26 0,000 0,06279683 0,07964638 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,06279683 0,07960442 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,06279683 0,0795625 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,06279683 0,07952062 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,06279683 0,07947879 ! molting cycle process GO:0022404 50 26 0,000 0,06279683 0,079437 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,06279683 0,07939526 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,06279683 0,07935356 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,06279683 0,07931191 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,06279683 0,0792703 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,06279683 0,07922873 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,06279683 0,0791872 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,06279683 0,07914572 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,06279683 0,07910428 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,06279683 0,07906289 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,06279683 0,07902154 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,06279683 0,07898023 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,06279683 0,07893897 ! blastocyst development GO:0001824 49 26 0,000 0,06279683 0,07889775 ! leukocyte proliferation GO:0070661 52 26 0,000 0,06279683 0,07885657 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,06279683 0,07881543 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,06279683 0,07877434 ! neuron fate commitment GO:0048663 48 27 0,000 0,06513276 0,08166202 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,06513276 0,08161949 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,06513276 0,081577 ! iron ion transport GO:0006826 59 27 0,000 0,06513276 0,08153455 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,06513276 0,08149215 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,06513276 0,0814498 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,06513276 0,08140749 ! fat cell differentiation GO:0045444 50 27 0,000 0,06513276 0,08136522 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,06513276 0,081323 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,06513276 0,08128082 ! autophagy GO:0006914 41 27 0,000 0,06513276 0,08123868 ! male gonad development GO:0008584 44 27 0,000 0,06513276 0,08119659 ! response to toxin GO:0009636 47 27 0,000 0,06513276 0,08115454 ! primary neural tube formation GO:0014020 51 27 0,000 0,06513276 0,08111253 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,06513276 0,08107057 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,06513276 0,08102865 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,06513276 0,08098678 ! glutathione metabolic process GO:0006749 39 27 0,000 0,06513276 0,08094494 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,06513276 0,08090316 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,06513276 0,08086141 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,06513276 0,08081971 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,06746293 0,08366795 ! circadian rhythm GO:0007623 50 28 0,000 0,06746293 0,08362484 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,06746293 0,08358178 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,06746293 0,08353876 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,06746293 0,08349579 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,06746293 0,08345286 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,06746293 0,08340998 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,06746293 0,08336714 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,06746293 0,08332434 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,06746293 0,08328159 ! synaptogenesis GO:0007416 42 28 0,000 0,06746293 0,08323888 ! lipid oxidation GO:0034440 43 28 0,000 0,06746293 0,08319622 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,06746293 0,0831536 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,06746293 0,08311102 ! translational initiation GO:0006413 65 29 0,000 0,06978738 0,08593062 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,06978738 0,08588667 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,06978738 0,08584276 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,06978738 0,0857989 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,06978738 0,08575508 ! catechol metabolic process GO:0009712 54 29 0,000 0,06978738 0,0857113 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,06978738 0,08566757 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,06978738 0,08562389 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,06978738 0,08558024 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,06978738 0,08553665 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,06978738 0,08549309 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,06978738 0,08544959 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,06978738 0,08540612 ! detection of light stimulus GO:0009583 38 29 0,000 0,06978738 0,0853627 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,06978738 0,08531933 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,06978738 0,085276 ! tissue homeostasis GO:0001894 48 29 0,000 0,06978738 0,08523271 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,06978738 0,08518947 ! phenol metabolic process GO:0018958 55 30 0,000 0,07210611 0,08797531 ! zinc ion transport GO:0006829 45 30 0,000 0,07210611 0,08793072 ! membrane docking GO:0022406 61 30 0,000 0,07210611 0,08788617 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,07210611 0,08784167 ! cell junction assembly GO:0034329 78 30 0,000 0,07210611 0,08779722 ! regulation of innate immune response GO:0045088 51 30 0,000 0,07210611 0,08775281 ! acute-phase response GO:0006953 49 30 0,000 0,07210611 0,08770844 ! myofibril assembly GO:0030239 47 30 0,000 0,07210611 0,08766412 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,07210611 0,08761985 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,07210611 0,08757562 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,07210611 0,08753143 ! phospholipid transport GO:0015914 51 30 0,000 0,07210611 0,08748729 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,07210611 0,0874432 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,07210611 0,08739914 ! eye morphogenesis GO:0048592 60 30 0,000 0,07210611 0,08735514 ! response to heat GO:0009408 50 30 0,000 0,07210611 0,08731117 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,07441914 0,09006662 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,07441914 0,09002134 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,07441914 0,0899761 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,07441914 0,08993091 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,07441914 0,08988577 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,07441914 0,08984067 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,07441914 0,08979561 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,07441914 0,0897506 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,07441914 0,08970563 ! ovulation cycle process GO:0022602 49 31 0,000 0,07441914 0,08966071 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,07441914 0,08961584 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,07441914 0,08957101 ! peptide transport GO:0015833 55 31 0,000 0,07441914 0,08952622 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,07441914 0,08948148 ! iron ion homeostasis GO:0055072 54 31 0,000 0,07441914 0,08943679 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,07441914 0,08939213 ! mesoderm formation GO:0001707 69 31 0,000 0,07441914 0,08934753 ! natural killer cell activation GO:0030101 45 31 0,000 0,07441914 0,08930297 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,07441914 0,08925845 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,07441914 0,08921397 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,07441914 0,08916954 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,07441914 0,08912516 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,07672648 0,09184274 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,07672648 0,09179707 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,07672648 0,09175144 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,07672648 0,09170586 ! cholesterol transport GO:0030301 56 32 0,000 0,07672648 0,09166033 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,07672648 0,09161484 ! spliceosome assembly GO:0000245 67 32 0,000 0,07672648 0,09156939 ! spindle organization GO:0007051 46 32 0,000 0,07672648 0,091524 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,07672648 0,09147864 ! metanephros development GO:0001656 74 32 0,000 0,07672648 0,09143333 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,07672648 0,09138807 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,07672648 0,09134285 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,07672648 0,09129768 ! muscle cell development GO:0055001 49 32 0,000 0,07672648 0,09125255 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,07672648 0,09120746 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,07672648 0,09116242 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,07672648 0,09111742 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,07672648 0,09107247 ! ovulation cycle GO:0042698 51 32 0,000 0,07672648 0,09102756 ! BMP signaling pathway GO:0030509 64 32 0,000 0,07672648 0,0909827 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,07672648 0,09093788 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,07672648 0,09089311 ! gene silencing GO:0016458 65 32 0,000 0,07672648 0,09084838 ! post-embryonic development GO:0009791 69 33 0,000 0,07902814 0,09352764 ! protein targeting to membrane GO:0006612 68 33 0,000 0,07902814 0,09348166 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,07902814 0,09343572 ! ceramide metabolic process GO:0006672 64 33 0,000 0,07902814 0,09338983 ! formation of primary germ layer GO:0001704 72 33 0,000 0,07902814 0,09334399 ! cell fate specification GO:0001708 52 33 0,000 0,07902814 0,09329818 ! sterol transport GO:0015918 57 33 0,000 0,07902814 0,09325243 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,07902814 0,09320672 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,07902814 0,09316105 ! adult locomotory behavior GO:0008344 59 33 0,000 0,07902814 0,09311543 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,07902814 0,09306985 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,08132414 0,09572695 ! glial cell differentiation GO:0010001 63 34 0,000 0,08132414 0,09568014 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,08132414 0,09563337 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,08132414 0,09558665 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,08132414 0,09553998 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,08132414 0,09549335 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,08132414 0,09544677 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,08132414 0,09540023 ! mismatch repair GO:0006298 46 34 0,000 0,08132414 0,09535374 ! spermatid development GO:0007286 63 34 0,000 0,08132414 0,0953073 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,08132414 0,09526089 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,08132414 0,09521454 ! placenta development GO:0001890 53 34 0,000 0,08132414 0,09516823 ! regulation of muscle development GO:0048634 70 35 0,000 0,08361449 0,09780091 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,08361449 0,09775339 ! negative regulation of secretion GO:0051048 63 35 0,000 0,08361449 0,09770591 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,08361449 0,09765848 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,08361449 0,0976111 ! odontogenesis GO:0042476 66 35 0,000 0,08361449 0,09756376 ! female gonad development GO:0008585 58 35 0,000 0,08361449 0,09751647 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,08361449 0,09746922 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,08361449 0,09742202 ! cytokine production GO:0001816 59 35 0,000 0,08361449 0,09737486 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,08361449 0,09732775 ! neural tube formation GO:0001841 67 35 0,000 0,08361449 0,09728069 ! vesicle localization GO:0051648 64 35 0,000 0,08361449 0,09723367 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,08589921 0,09984227 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,08589921 0,09979406 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,08589921 0,0997459 ! cell junction organization GO:0034330 86 36 0,000 0,08589921 0,09969778 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,08589921 0,09964971 ! positive regulation of cell development GO:0010720 80 36 0,000 0,08589921 0,09960169 ! regulation of proteolysis GO:0030162 72 36 0,000 0,08589921 0,09955371 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,08589921 0,09950578 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,08589921 0,09945789 ! aerobic respiration GO:0009060 55 36 0,000 0,08589921 0,09941005 ! embryonic organ development GO:0048568 57 36 0,000 0,08589921 0,09936226 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,08589921 0,09931451 ! RNA export from nucleus GO:0006405 56 37 0,000 0,08817831 0,10190058 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,08817831 0,10185166 ! meiosis I GO:0007127 65 37 0,000 0,08817831 0,10180279 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,08817831 0,10175396 ! sister chromatid segregation GO:0000819 58 37 0,000 0,08817831 0,10170518 ! actomyosin structure organization GO:0031032 62 37 0,000 0,08817831 0,10165645 ! organic anion transport GO:0015711 68 37 0,000 0,08817831 0,10160776 ! tissue remodeling GO:0048771 76 37 0,000 0,08817831 0,10155912 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,08817831 0,10151053 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,08817831 0,10146199 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,08817831 0,10141349 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,08817831 0,10136503 ! pigment metabolic process GO:0042440 80 37 0,000 0,08817831 0,10131662 ! spermatid differentiation GO:0048515 66 37 0,000 0,08817831 0,10126826 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,0904518 0,10382969 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,0904518 0,10378018 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,0904518 0,10373071 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,0904518 0,10368129 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,0904518 0,10363192 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,0904518 0,1035826 ! lipid homeostasis GO:0055088 67 38 0,000 0,0904518 0,10353332 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,0904518 0,10348409 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,0904518 0,1034349 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,0904518 0,10338576 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,0904518 0,10333667 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,0904518 0,10328763 ! glucan metabolic process GO:0044042 62 38 0,000 0,0904518 0,10323863 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,0927197 0,10577695 ! learning GO:0007612 77 39 0,000 0,0927197 0,10572682 ! ear morphogenesis GO:0042471 60 39 0,000 0,0927197 0,10567674 ! organic ether metabolic process GO:0018904 55 39 0,000 0,0927197 0,1056267 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,0927197 0,10557671 ! ion transmembrane transport GO:0034220 66 39 0,000 0,0927197 0,10552677 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,0927197 0,10547688 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,0927197 0,10542703 ! RNA modification GO:0009451 57 39 0,000 0,0927197 0,10537723 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,0927197 0,10532748 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,09498202 0,1078465 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,09498202 0,10779563 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,09498202 0,10774481 ! feeding behavior GO:0007631 59 40 0,000 0,09498202 0,10769403 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,09498202 0,1076433 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,09498202 0,10759262 ! cytokinesis GO:0000910 72 40 0,000 0,09498202 0,10754199 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,09723877 0,11004538 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,09723877 0,10999364 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,09723877 0,10994196 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,09723877 0,10989032 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,09723877 0,10983872 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,09723877 0,10978718 ! female gamete generation GO:0007292 61 41 0,000 0,09723877 0,10973569 ! polyol metabolic process GO:0019751 66 41 0,000 0,09723877 0,10968424 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,09948997 0,11217098 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,09948997 0,11211844 ! regulation of tube size GO:0035150 71 42 0,000 0,09948997 0,11206595 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,09948997 0,11201351 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,09948997 0,11196112 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,09948997 0,11190877 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,09948997 0,11185648 ! neuron migration GO:0001764 79 42 0,000 0,09948997 0,11180424 ! regulation of protein secretion GO:0050708 71 42 0,000 0,09948997 0,11175204 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,10173563 0,11422115 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,10173563 0,11416788 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,10173563 0,11411465 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,10173563 0,11406148 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,10173563 0,11400835 ! glucose transport GO:0015758 65 43 0,000 0,10173563 0,11395527 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,10173563 0,11390225 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,10173563 0,11384927 ! neural tube development GO:0021915 77 43 0,000 0,10173563 0,11379634 ! striated muscle contraction GO:0006941 77 43 0,000 0,10173563 0,11374346 ! phagocytosis GO:0006909 90 43 0,000 0,10173563 0,11369063 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,10173563 0,11363785 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,10397577 0,11608617 ! hexose transport GO:0008645 67 44 0,000 0,10397577 0,11603233 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,10397577 0,11597853 ! male sex differentiation GO:0046661 76 44 0,000 0,10397577 0,11592479 ! biopolymer methylation GO:0043414 84 44 0,000 0,10397577 0,1158711 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,10397577 0,11581745 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,10397577 0,11576386 ! developmental growth GO:0048589 82 44 0,000 0,10397577 0,11571031 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,10621039 0,11814249 ! glycolysis GO:0006096 65 45 0,000 0,10621039 0,11808789 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,10621039 0,11803335 ! leukocyte migration GO:0050900 68 45 0,000 0,10621039 0,11797885 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,10621039 0,11792441 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,10621039 0,11787002 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,10621039 0,11781567 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,10621039 0,11776138 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,10621039 0,11770714 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,10621039 0,11765295 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,10621039 0,1175988 ! cell growth GO:0016049 84 45 0,000 0,10621039 0,11754471 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,10843951 0,11995654 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,10843951 0,11990141 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,10843951 0,11984633 ! pigmentation GO:0043473 100 46 0,000 0,10843951 0,11979131 ! positive regulation of defense response GO:0031349 76 47 0,000 0,11066315 0,12219162 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,11066315 0,12213557 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,11066315 0,12207957 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,11066315 0,12202362 ! JNK cascade GO:0007254 91 47 0,000 0,11066315 0,12196773 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,11066315 0,12191188 ! methylation GO:0032259 90 47 0,000 0,11066315 0,12185608 ! cellular component disassembly GO:0022411 86 48 0,000 0,11288132 0,12424174 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,11288132 0,12418494 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,11288132 0,12412818 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,11288132 0,12407147 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,11288132 0,12401482 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,11288132 0,12395822 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,11509403 0,1263304 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,11509403 0,12627279 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,11509403 0,12621524 ! regulation of ion transport GO:0043269 77 49 0,000 0,11509403 0,12615773 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,11509403 0,12610029 ! peptide metabolic process GO:0006518 76 49 0,000 0,11509403 0,12604289 ! response to temperature stimulus GO:0009266 76 49 0,000 0,11509403 0,12598554 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,11509403 0,12592825 ! endocrine system development GO:0035270 104 49 0,000 0,11509403 0,12587101 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,11509403 0,12581382 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,11509403 0,12575669 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,11509403 0,1256996 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,11509403 0,12564257 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,11730129 0,12799406 ! neuromuscular process GO:0050905 99 50 0,000 0,11730129 0,12793604 ! inner ear development GO:0048839 79 50 0,000 0,11730129 0,12787807 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,11730129 0,12782015 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,11730129 0,12776229 ! viral infectious cycle GO:0019058 99 51 0,000 0,11950312 0,13010158 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,11950312 0,13004274 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,11950312 0,12998395 ! excretion GO:0007588 83 51 0,000 0,11950312 0,12992521 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,11950312 0,12986653 ! chromatin remodeling GO:0006338 109 51 0,000 0,11950312 0,1298079 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,11950312 0,12974932 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,11950312 0,1296908 ! vesicle organization GO:0016050 107 51 0,000 0,11950312 0,12963233 ! regulation of cell shape GO:0008360 125 51 0,000 0,11950312 0,12957391 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,11950312 0,12951554 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,12169953 0,13183659 ! membrane fusion GO:0006944 110 52 0,000 0,12169953 0,13177726 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,12169953 0,13171798 ! amino acid activation GO:0043038 92 52 0,000 0,12169953 0,13165875 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,12169953 0,13159958 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,12389053 0,13390863 ! RNA catabolic process GO:0006401 93 53 0,000 0,12389053 0,1338485 ! regulation of translational initiation GO:0006446 82 53 0,000 0,12389053 0,13378843 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,12389053 0,13372841 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,12389053 0,13366844 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,12389053 0,13360852 ! cell maturation GO:0048469 100 53 0,000 0,12389053 0,13354866 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,12389053 0,13348886 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,12607614 0,13578299 ! cell recognition GO:0008037 85 54 0,000 0,12607614 0,13572224 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,12607614 0,13566154 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,12607614 0,13560089 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,12607614 0,1355403 ! chloride transport GO:0006821 90 55 0,000 0,12825637 0,13782262 ! glucose catabolic process GO:0006007 82 55 0,000 0,12825637 0,13776109 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,12825637 0,13769961 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,12825637 0,1376382 ! gastrulation GO:0007369 112 55 0,000 0,12825637 0,13757683 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,12825637 0,13751552 ! RNA elongation GO:0006354 79 55 0,000 0,12825637 0,13745427 ! nuclear export GO:0051168 97 55 0,000 0,12825637 0,13739307 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,12825637 0,13733192 ! regulation of actin filament length GO:0030832 105 56 0,000 0,13043124 0,13959856 ! sensory perception of smell GO:0007608 80 56 0,000 0,13043124 0,13953649 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,13043124 0,13947447 ! proton transport GO:0015992 94 56 0,000 0,13043124 0,13941251 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,13043124 0,1393506 ! hydrogen transport GO:0006818 97 58 0,000 0,13476492 0,14391673 ! regulation of endocytosis GO:0030100 91 58 0,000 0,13476492 0,14385288 ! adult behavior GO:0030534 99 58 0,000 0,13476492 0,14378909 ! positive regulation of secretion GO:0051047 95 59 0,000 0,13692376 0,14602773 ! regulation of cellular component size GO:0032535 109 59 0,000 0,13692376 0,14596303 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,13692376 0,14589839 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,13692376 0,14583381 ! DNA catabolic process GO:0006308 86 59 0,000 0,13692376 0,14576928 ! establishment of organelle localization GO:0051656 109 59 0,000 0,13692376 0,14570481 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,13907729 0,14793101 ! regulation of heart contraction GO:0008016 110 60 0,000 0,13907729 0,14786564 ! camera-type eye development GO:0043010 116 60 0,000 0,13907729 0,14780033 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,13907729 0,14773508 ! kidney development GO:0001822 122 60 0,000 0,13907729 0,14766988 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,14122551 0,14988469 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,14122551 0,1498186 ! mesoderm development GO:0007498 119 61 0,000 0,14122551 0,14975257 ! tRNA processing GO:0008033 89 61 0,000 0,14122551 0,1496866 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,14122551 0,14962069 ! ear development GO:0043583 103 62 0,000 0,14336845 0,15182416 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,14336845 0,15175736 ! gonad development GO:0008406 98 62 0,000 0,14336845 0,15169063 ! regulation of mitosis GO:0007088 105 63 0,000 0,14550611 0,1538847 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,14550611 0,15381709 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,14550611 0,15374954 ! detection of external stimulus GO:0009581 91 63 0,000 0,14550611 0,15368204 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,14550611 0,15361461 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,14763851 0,15579748 ! cell redox homeostasis GO:0045454 102 64 0,000 0,14763851 0,15572917 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,14763851 0,15566093 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,14763851 0,15559275 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,14763851 0,15552462 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,14976565 0,15769635 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,14976565 0,15762736 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,14976565 0,15755844 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,14976565 0,15748958 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,14976565 0,15742078 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,15188756 0,15958143 ! extracellular matrix organization GO:0030198 133 66 0,000 0,15188756 0,15951177 ! secondary metabolic process GO:0019748 116 66 0,000 0,15188756 0,15944218 ! developmental maturation GO:0021700 116 66 0,000 0,15188756 0,15937264 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,15400424 0,16152319 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,15400424 0,16145281 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,15400424 0,16138249 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,15400424 0,16131224 ! hexose catabolic process GO:0019320 104 67 0,000 0,15400424 0,16124204 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,15400424 0,1611719 ! adaptive immune response GO:0002250 119 67 0,000 0,15400424 0,16110183 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,15400424 0,16103181 ! amino acid transport GO:0006865 125 68 0,000 0,15611571 0,16316872 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,15611571 0,16309787 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,15611571 0,16302708 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,15611571 0,16295636 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,15822198 0,1650833 ! urogenital system development GO:0001655 137 69 0,000 0,15822198 0,16501174 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,15822198 0,16494025 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,15822198 0,16486881 ! antigen processing and presentation GO:0019882 104 69 0,000 0,15822198 0,16479744 ! appendage morphogenesis GO:0035107 135 70 0,000 0,16032307 0,16691359 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,16241897 0,16902251 ! reproductive structure development GO:0048608 113 71 0,000 0,16241897 0,16894944 ! appendage development GO:0048736 136 71 0,000 0,16241897 0,16887643 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,16241897 0,16880348 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,16241897 0,16873059 ! regulation of immune effector process GO:0002697 137 71 0,000 0,16241897 0,16865777 ! acute inflammatory response GO:0002526 113 72 0,000 0,16450972 0,17075513 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,16450972 0,1706815 ! carbohydrate transport GO:0008643 110 72 0,000 0,16450972 0,17060793 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,16450972 0,17053442 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,16450972 0,17046098 ! regulation of blood pressure GO:0008217 125 73 0,000 0,16659532 0,17254771 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,16659532 0,17247347 ! fertilization GO:0009566 90 73 0,000 0,16659532 0,17239928 ! transition metal ion transport GO:0000041 126 74 0,000 0,16867578 0,17447718 ! meiosis GO:0007126 121 74 0,000 0,16867578 0,1744022 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,16867578 0,17432729 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,16867578 0,17425244 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,16867578 0,17417765 ! eye development GO:0001654 143 74 0,000 0,16867578 0,17410293 ! organelle localization GO:0051640 136 74 0,000 0,16867578 0,17402827 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,17075111 0,17609395 ! meiotic cell cycle GO:0051321 122 75 0,000 0,17075111 0,1760185 ! rhythmic process GO:0048511 128 75 0,000 0,17075111 0,17594312 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,17282134 0,17800006 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,17282134 0,17792389 ! defense response to bacterium GO:0042742 89 76 0,000 0,17282134 0,17784779 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,17282134 0,17777176 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,17282134 0,17769579 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,17488646 0,17974234 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,17488646 0,1796656 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,17488646 0,17958892 ! blood coagulation GO:0007596 146 78 0,000 0,1769465 0,18162683 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,1769465 0,18154937 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,1769465 0,18147199 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,1769465 0,18139467 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,17900146 0,18342313 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,17900146 0,18334505 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,17900146 0,18326703 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,17900146 0,18318908 ! muscle cell differentiation GO:0042692 159 80 0,000 0,18105136 0,18520815 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,18105136 0,18512944 ! inorganic anion transport GO:0015698 138 80 0,000 0,18105136 0,1850508 ! digestion GO:0007586 112 81 0,000 0,18309621 0,18706135 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,18309621 0,18698195 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,18309621 0,18690262 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,18513602 0,1889047 ! response to nutrient GO:0007584 125 82 0,000 0,18513602 0,18882462 ! hemostasis GO:0007599 158 84 0,000 0,18920058 0,19288839 ! regulation of ligase activity GO:0051340 142 84 0,000 0,18920058 0,19280669 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,18920058 0,19272506 ! response to unfolded protein GO:0006986 131 85 0,000 0,19122535 0,19470512 ! nucleosome assembly GO:0006334 122 85 0,000 0,19122535 0,19462276 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,19122535 0,19454047 ! amine biosynthetic process GO:0009309 138 86 0,000 0,19324514 0,19651217 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,19324514 0,19642915 ! chromatin assembly GO:0031497 124 86 0,000 0,19324514 0,1963462 ! tube morphogenesis GO:0035239 176 86 0,000 0,19324514 0,19626332 ! alcohol catabolic process GO:0046164 130 86 0,000 0,19324514 0,1961805 ! amine transport GO:0015837 155 86 0,000 0,19324514 0,19609776 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,19525994 0,19805878 ! cellular respiration GO:0045333 135 88 0,000 0,19726978 0,2000131 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,19726978 0,19992885 ! regulation of neurological system process GO:0031644 148 88 0,000 0,19726978 0,19984467 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,19726978 0,19976056 ! cellular defense response GO:0006968 114 89 0,000 0,19927467 0,20170587 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,19927467 0,20162105 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,20127462 0,20355894 ! sex differentiation GO:0007548 145 90 0,000 0,20127462 0,20347341 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,20127462 0,20338796 ! sterol metabolic process GO:0016125 152 91 0,000 0,20326963 0,20531769 ! response to protein stimulus GO:0051789 149 91 0,000 0,20326963 0,20523153 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,20326963 0,20514544 ! regulation of defense response GO:0031347 149 92 0,000 0,20525973 0,20706705 ! nucleosome organization GO:0034728 138 92 0,000 0,20525973 0,20698027 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,20525973 0,20689356 ! vitamin metabolic process GO:0006766 139 92 0,000 0,20525973 0,20680692 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,20724493 0,20871967 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,20724493 0,20863234 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,20724493 0,20854509 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,20922523 0,2104498 ! female pregnancy GO:0007565 164 94 0,000 0,20922523 0,21036185 ! transcription initiation GO:0006352 153 94 0,000 0,20922523 0,21027398 ! forebrain development GO:0030900 188 95 0,000 0,21120066 0,21217068 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,21120066 0,21208213 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,21317121 0,2139716 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,21317121 0,21388237 ! positive regulation of immune response GO:0050778 156 96 0,000 0,21317121 0,21379322 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,21513691 0,21567475 ! protein ubiquitination GO:0016567 217 97 0,000 0,21513691 0,21558492 ! hormone metabolic process GO:0042445 157 97 0,000 0,21513691 0,21549517 ! response to virus GO:0009615 160 98 0,000 0,21709776 0,21736879 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,21709776 0,21727837 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,21709776 0,21718803 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,21905377 0,21905377