pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6510-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 4,000 8,627E-09 1,984E-05 ! positive regulation of intracellular transport GO:0032388 29 19 4,000 1,61E-08 1,851E-05 ! spliceosomal snRNP biogenesis GO:0000387 28 22 4,000 3,609E-08 2,767E-05 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 2,000 8,164E-07 4,694E-04 GO:0046831|regulation of RNA export from nucleus, ! regulation of nucleocytoplasmic transport GO:0046822 70 42 4,000 1,088E-06 5,006E-04 ! regulation of intracellular transport GO:0032386 78 49 4,000 2,382E-06 9,13E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 2,000 4,528E-06 1,488E-03 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 4,528E-06 1,302E-03 ! phosphatidylinositol metabolic process GO:0046488 22 17 2,000 5,344E-05 0,01365669 ! positive regulation of growth GO:0045927 67 50 3,000 6,87E-05 0,01580089 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 7,43E-05 0,0155351 ! calcium-independent cell-cell adhesion GO:0016338 21 19 2,000 7,567E-05 0,01450327 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 7,567E-05 0,01338764 ! phosphoinositide metabolic process GO:0030384 87 60 3,000 1,407E-04 0,02311474 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 3,000 1,407E-04 0,02157376 ! negative regulation of ligase activity GO:0051352 91 61 3,000 1,501E-04 0,02157279 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 3,000 1,501E-04 0,0203038 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 3,000 1,599E-04 0,02043017 ! protein amino acid alkylation GO:0008213 39 25 2,000 1,762E-04 0,02133224 GO:0006479|protein amino acid methylation, ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,899E-04 0,02183302 ! 2-oxoglutarate metabolic process GO:0006103 7 5 1,000 1,899E-04 0,02079335 ! valine metabolic process GO:0006573 8 5 1,000 1,899E-04 0,0198482 ! positive regulation of organ growth GO:0046622 6 5 1,000 1,899E-04 0,01898524 ! muscle cell proliferation GO:0033002 8 5 1,000 1,899E-04 0,01819418 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 1,899E-04 0,01746642 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 3,000 1,921E-04 0,01699558 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 3,000 1,921E-04 0,01636611 ! positive regulation of ligase activity GO:0051351 99 69 3,000 2,421E-04 0,01988489 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 3,000 2,703E-04 0,02143542 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 2,84E-04 0,02177063 ! mRNA stabilization GO:0048255 15 6 1,000 2,84E-04 0,02106835 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 1,000 2,84E-04 0,02040996 GO:0031958|corticosteroid receptor signaling pathway, ! ER overload response GO:0006983 7 6 1,000 2,84E-04 0,01979148 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 1,000 2,84E-04 0,01920938 ! regulation of ligase activity GO:0051340 114 75 3,000 3,336E-04 0,02192402 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 3,964E-04 0,02532651 ! oxaloacetate metabolic process GO:0006107 9 7 1,000 3,964E-04 0,02464201 ! microtubule bundle formation GO:0001578 8 7 1,000 3,964E-04 0,02399353 ! T-helper 1 type immune response GO:0042088 11 7 1,000 3,964E-04 0,02337831 ! cardiac muscle cell differentiation GO:0055007 12 7 1,000 3,964E-04 0,02279386 ! RNA export from nucleus GO:0006405 44 33 2,000 4,076E-04 0,02286394 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 3,000 4,27E-04 0,02338173 GO:0010498|proteasomal protein catabolic process, ! mRNA transport GO:0051028 121 81 3,000 4,477E-04 0,02394468 ! regulation of intracellular protein transport GO:0033157 59 35 2,000 4,858E-04 0,02539624 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 5,27E-04 0,02693779 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 5,27E-04 0,02635218 ! induction of positive chemotaxis GO:0050930 14 8 1,000 5,27E-04 0,0257915 ! succinate metabolic process GO:0006105 14 8 1,000 5,27E-04 0,02525418 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 5,27E-04 0,02473879 ! keratinocyte proliferation GO:0043616 12 8 1,000 5,27E-04 0,02424401 ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 5,27E-04 0,02376864 ! regulation of vascular permeability GO:0043114 12 8 1,000 5,27E-04 0,02331155 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 1,000 5,27E-04 0,02287171 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 5,27E-04 0,02244816 ! positive regulation of MAP kinase activity GO:0043406 121 85 3,000 5,376E-04 0,02248218 ! establishment of RNA localization GO:0051236 128 88 3,000 6,13E-04 0,02517772 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! regulation of epithelial cell proliferation GO:0050678 71 39 2,000 6,699E-04 0,02702981 ! lung alveolus development GO:0048286 17 9 1,000 6,757E-04 0,02679472 ! L-serine metabolic process GO:0006563 13 9 1,000 6,757E-04 0,02634057 ! phosphagen metabolic process GO:0006599 12 9 1,000 6,757E-04 0,02590156 GO:0006600|creatine metabolic process, ! retinoic acid receptor signaling pathway GO:0048384 15 9 1,000 6,757E-04 0,02547695 ! motor axon guidance GO:0008045 14 9 1,000 6,757E-04 0,02506603 ! mRNA cleavage GO:0006379 13 9 1,000 6,757E-04 0,02466816 ! regulation of RNA splicing GO:0043484 14 9 1,000 6,757E-04 0,02428272 ! localization within membrane GO:0051668 15 9 1,000 6,757E-04 0,02390914 ! RNA localization GO:0006403 135 91 3,000 6,956E-04 0,02424228 ! induction of apoptosis by intracellular signals GO:0008629 67 40 2,000 7,219E-04 0,02478156 ! positive regulation of protein transport GO:0051222 55 40 2,000 7,219E-04 0,02441712 ! glycerophospholipid metabolic process GO:0006650 130 92 3,000 7,249E-04 0,02416196 ! biopolymer methylation GO:0043414 62 41 2,000 7,764E-04 0,02551133 ! regulation of B cell proliferation GO:0030888 15 10 1,000 8,422E-04 0,02728272 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 8,422E-04 0,02690379 ! blood vessel remodeling GO:0001974 21 10 1,000 8,422E-04 0,02653525 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 8,422E-04 0,02617666 ! regulation of bone resorption GO:0045124 24 10 1,000 8,422E-04 0,02582764 ! regulation of organ growth GO:0046620 11 10 1,000 8,422E-04 0,0254878 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 8,422E-04 0,02515679 ! cardiac cell differentiation GO:0035051 16 10 1,000 8,422E-04 0,02483427 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 3,000 8,504E-04 0,02475911 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 8,932E-04 0,02567971 ! methylation GO:0032259 64 43 2,000 8,932E-04 0,02536268 ! regulation of mast cell proliferation GO:0070666 64 44 2,000 9,555E-04 0,02680176 ! protein amino acid autophosphorylation GO:0046777 80 45 2,000 1,021E-03 0,02828074 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 1,026E-03 0,02810451 ! regulation of positive chemotaxis GO:0050926 17 11 1,000 1,026E-03 0,02777387 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 1,026E-03 0,02745091 ! regulation of mRNA processing GO:0050684 18 11 1,000 1,026E-03 0,02713539 ! regulation of leukocyte migration GO:0002685 24 11 1,000 1,026E-03 0,02682703 ! serine family amino acid biosynthetic process GO:0009070 13 11 1,000 1,026E-03 0,0265256 ! negative regulation of mast cell proliferation GO:0070667 17 11 1,000 1,026E-03 0,02623087 GO:0042130|negative regulation of T cell proliferation, ! response to UV GO:0009411 75 46 2,000 1,088E-03 0,02750715 ! regulation of leukocyte proliferation GO:0070663 71 47 2,000 1,159E-03 0,02897166 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage condensation GO:0001502 18 12 1,000 1,228E-03 0,03037478 ! positive regulation of cell growth GO:0030307 16 12 1,000 1,228E-03 0,03005164 ! regulation of mRNA stability GO:0043488 27 12 1,000 1,228E-03 0,02973531 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 1,228E-03 0,02942556 ! response to cold GO:0009409 14 12 1,000 1,228E-03 0,02912221 ! nuclear export GO:0051168 69 48 2,000 1,232E-03 0,02891965 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 1,447E-03 0,03362571 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 1,447E-03 0,03328945 ! regulation of RNA stability GO:0043487 28 13 1,000 1,447E-03 0,03295985 ! positive regulation of cell migration GO:0030335 92 51 2,000 1,47E-03 0,03313961 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 1,684E-03 0,03759902 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 1,684E-03 0,03723749 ! negative regulation of microtubule depolymerization GO:0007026 31 14 1,000 1,684E-03 0,03688284 GO:0031114|regulation of microtubule depolymerization, ! negative regulation of caspase activity GO:0043154 20 14 1,000 1,684E-03 0,03653489 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 1,684E-03 0,03619344 ! positive regulation of cell motion GO:0051272 99 56 2,000 1,926E-03 0,04100958 ! positive regulation of cell size GO:0045793 20 15 1,000 1,937E-03 0,04087858 ! skin development GO:0043588 25 15 1,000 1,937E-03 0,04050696 ! lipid phosphorylation GO:0046834 23 15 1,000 1,937E-03 0,04014203 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 1,937E-03 0,03978362 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 1,937E-03 0,03943155 ! negative regulation of leukocyte proliferation GO:0070664 25 15 1,000 1,937E-03 0,03908566 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 1,000 1,937E-03 0,03874579 ! negative regulation of protein kinase activity GO:0006469 99 57 2,000 2,026E-03 0,04017572 ! negative regulation of kinase activity GO:0033673 100 58 2,000 2,13E-03 0,04187287 ! mitotic chromosome condensation GO:0007076 25 16 1,000 2,208E-03 0,04303218 ! branched chain family amino acid metabolic process GO:0009081 24 16 1,000 2,208E-03 0,04267056 ! negative regulation of transferase activity GO:0051348 105 61 2,000 2,461E-03 0,0471711 ! negative regulation of peptidase activity GO:0010466 23 17 1,000 2,495E-03 0,0474252 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 2,495E-03 0,04703647 ! neuromuscular junction development GO:0007528 23 17 1,000 2,495E-03 0,04665406 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 1,000 2,495E-03 0,04627781 ! peptidyl-serine modification GO:0018209 27 17 1,000 2,495E-03 0,04590759 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 2,495E-03 0,04554324 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 2,000 2,699E-03 0,04887064 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 2,000 2,699E-03 0,04848884 ! protein amino acid ADP-ribosylation GO:0006471 27 18 1,000 2,799E-03 0,04990215 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 2,799E-03 0,04951828 ! response to retinoic acid GO:0032526 25 18 1,000 2,799E-03 0,04914028 ! estrogen receptor signaling pathway GO:0030520 30 18 1,000 2,799E-03 0,04876801 ! negative regulation of T cell activation GO:0050868 25 18 1,000 2,799E-03 0,04840133 ! regulation of caspase activity GO:0043281 97 65 2,000 2,95E-03 0,05062735 ! regulation of Rho protein signal transduction GO:0035023 111 66 2,000 3,08E-03 0,05247993 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 3,119E-03 0,05275176 ! response to vitamin A GO:0033189 26 19 1,000 3,119E-03 0,05236672 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 3,119E-03 0,05198725 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 3,119E-03 0,05161324 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 3,215E-03 0,0528114 ! response to vitamin GO:0033273 29 20 1,000 3,456E-03 0,05637376 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 1,000 3,456E-03 0,05597676 ! chromosome condensation GO:0030261 31 20 1,000 3,456E-03 0,05558531 ! positive regulation of locomotion GO:0040017 35 20 1,000 3,456E-03 0,0551993 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of B cell activation GO:0050871 31 20 1,000 3,456E-03 0,05481862 ! positive regulation of phosphorylation GO:0042327 102 70 2,000 3,639E-03 0,05732313 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 1,000 3,809E-03 0,05959469 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 3,809E-03 0,05919202 ! regulation of chemotaxis GO:0050920 36 21 1,000 3,809E-03 0,05879476 ! dendrite development GO:0016358 35 21 1,000 3,809E-03 0,05840279 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 3,809E-03 0,05801602 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 1,000 3,809E-03 0,05763433 GO:0060415|muscle tissue morphogenesis, ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 3,809E-03 0,05725764 ! regulation of peptidase activity GO:0052547 106 72 2,000 3,94E-03 0,05883894 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 2,000 3,94E-03 0,05845934 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 1,000 4,178E-03 0,06159656 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 4,178E-03 0,06120422 ! dicarboxylic acid metabolic process GO:0043648 33 22 1,000 4,178E-03 0,06081686 ! vasculogenesis GO:0001570 33 22 1,000 4,178E-03 0,06043436 ! regulation of behavior GO:0050795 38 22 1,000 4,178E-03 0,06005664 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 4,255E-03 0,06078954 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 1,000 4,563E-03 0,06477963 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 4,563E-03 0,06438221 ! myelination GO:0042552 35 23 1,000 4,563E-03 0,06398963 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 4,563E-03 0,06360182 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 4,563E-03 0,06321867 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 4,563E-03 0,06284012 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 4,563E-03 0,06246607 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 4,563E-03 0,06209645 ! regulation of protein transport GO:0051223 114 76 2,000 4,586E-03 0,06204364 GO:0070201|regulation of establishment of protein localization, ! one-carbon metabolic process GO:0006730 110 77 2,000 4,757E-03 0,06398018 ! insulin receptor signaling pathway GO:0008286 40 24 1,000 4,963E-03 0,06637093 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 4,963E-03 0,06598728 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 1,000 4,963E-03 0,06560804 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 4,963E-03 0,06523314 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 5,38E-03 0,07030246 GO:0045936|negative regulation of phosphate metabolic process, ! male gonad development GO:0008584 33 25 1,000 5,38E-03 0,06990527 ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 5,38E-03 0,06951255 ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 5,38E-03 0,06912421 ! ossification GO:0001503 134 82 2,000 5,669E-03 0,07243991 GO:0060348|bone development, ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 5,811E-03 0,07384682 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 5,811E-03 0,07344107 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 5,811E-03 0,07303975 ! negative regulation of leukocyte activation GO:0002695 39 27 1,000 6,259E-03 0,07823153 ! serine family amino acid metabolic process GO:0009069 37 27 1,000 6,259E-03 0,07780866 ! regulation of protein localization GO:0032880 132 85 2,000 6,264E-03 0,07745318 ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 6,47E-03 0,0795737 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 1,000 6,721E-03 0,08222282 ! positive regulation of multicellular organism growth GO:0040018 38 28 1,000 6,721E-03 0,08178778 ! ensheathment of neurons GO:0007272 43 28 1,000 6,721E-03 0,08135732 GO:0008366|axon ensheathment, ! regulation of B cell activation GO:0050864 42 28 1,000 6,721E-03 0,08093136 ! interphase GO:0051325 159 88 2,000 6,894E-03 0,08258319 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 7,198E-03 0,08578146 ! spliceosome assembly GO:0000245 49 30 1,000 7,69E-03 0,09117567 ! regulation of microtubule-based process GO:0032886 58 30 1,000 7,69E-03 0,0907081 ! negative regulation of cell activation GO:0050866 44 30 1,000 7,69E-03 0,0902453 ! peptidyl-amino acid modification GO:0018193 147 93 2,000 8,026E-03 0,09369963 ! mammary gland development GO:0030879 57 31 1,000 8,198E-03 0,09522397 ! angiogenesis GO:0001525 149 95 2,000 8,507E-03 0,09832294 ! mitotic sister chromatid segregation GO:0000070 45 32 1,000 8,719E-03 0,10027154 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 1,000 8,719E-03 0,09977268 ! peripheral nervous system development GO:0007422 53 32 1,000 8,719E-03 0,09927876 ! calcium-mediated signaling GO:0019722 50 32 1,000 8,719E-03 0,0987897 ! in utero embryonic development GO:0001701 147 96 2,000 8,754E-03 0,09869774 ! response to light stimulus GO:0009416 153 96 2,000 8,754E-03 0,09821629 ! sister chromatid segregation GO:0000819 46 33 1,000 9,256E-03 0,10333814 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 9,256E-03 0,10283892 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 9,806E-03 0,10843307 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 1,000 9,806E-03 0,10791425 ! development of primary male sexual characteristics GO:0046546 44 34 1,000 9,806E-03 0,10740038 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 9,806E-03 0,10689137 ! keratinocyte differentiation GO:0030216 47 35 1,000 0,01037099 0,11251542 ! regulation of action potential in neuron GO:0019228 54 35 1,000 0,01037099 0,11198718 ! glycogen metabolic process GO:0005977 48 35 1,000 0,01037099 0,11146388 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,01037099 0,11094544 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 1,000 0,01037099 0,1104318 ! cellular amide metabolic process GO:0043603 52 36 1,000 0,01094997 0,11605955 ! tissue remodeling GO:0048771 62 36 1,000 0,01094997 0,11552717 ! glucan metabolic process GO:0044042 49 36 1,000 0,01094997 0,11499965 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 1,000 0,01154293 0,12067607 ! protein amino acid N-linked glycosylation GO:0006487 49 37 1,000 0,01154293 0,12013002 ! striated muscle cell differentiation GO:0051146 54 38 1,000 0,01214974 0,12587569 ! regulation of T cell proliferation GO:0042129 58 38 1,000 0,01214974 0,12531123 ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 0,01277027 0,13112335 ! multicellular organismal metabolic process GO:0044236 50 39 1,000 0,01277027 0,13054058 ! male sex differentiation GO:0046661 53 39 1,000 0,01277027 0,12996297 ! synapse organization GO:0050808 55 39 1,000 0,01277027 0,12939044 ! positive regulation of response to external stimulus GO:0032103 65 40 1,000 0,0134044 0,13521982 ! peptide metabolic process GO:0006518 56 40 1,000 0,0134044 0,13462934 ! epidermal cell differentiation GO:0009913 53 40 1,000 0,0134044 0,13404399 ! JAK-STAT cascade GO:0007259 53 40 1,000 0,0134044 0,13346372 ! energy reserve metabolic process GO:0006112 59 41 1,000 0,01405199 0,1393085 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,01405199 0,13871061 ! regulation of T cell differentiation GO:0045580 59 41 1,000 0,01405199 0,13811783 ! regulation of JAK-STAT cascade GO:0046425 61 42 1,000 0,01471291 0,1439987 ! regulation of cell shape GO:0008360 78 42 1,000 0,01471291 0,14338854 ! positive regulation of binding GO:0051099 59 43 1,000 0,01538704 0,14932573 ! response to insulin stimulus GO:0032868 63 43 1,000 0,01538704 0,14869831 ! ribonucleoprotein complex assembly GO:0022618 70 44 1,000 0,01607426 0,1546895 ! regulation of action potential GO:0001508 71 44 1,000 0,01607426 0,15404496 ! cellular amino acid biosynthetic process GO:0008652 51 44 1,000 0,01607426 0,15340577 ! positive regulation of cell cycle GO:0045787 77 45 1,000 0,01677443 0,15942639 ! vascular process in circulatory system GO:0003018 69 45 1,000 0,01677443 0,15877031 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 0,01748743 0,16484056 ! negative regulation of immune system process GO:0002683 73 47 1,000 0,01821315 0,17098057 ! response to temperature stimulus GO:0009266 62 48 1,000 0,01895145 0,17718834 ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 0,01895145 0,17647098 ! heart morphogenesis GO:0003007 65 48 1,000 0,01895145 0,1757594 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 1,000 0,01895145 0,17505354 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 0,01895145 0,17435333 ! regulation of angiogenesis GO:0045765 94 49 1,000 0,01970221 0,18053822 ! integrin-mediated signaling pathway GO:0007229 81 49 1,000 0,01970221 0,17982179 ! cartilage development GO:0051216 70 49 1,000 0,01970221 0,17911104 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,02046532 0,18531592 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 0,02046532 0,18458919 ! lipid modification GO:0030258 73 50 1,000 0,02046532 0,18386814 ! regulation of multicellular organism growth GO:0040014 65 50 1,000 0,02046532 0,1831527 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,02124066 0,18935469 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 0,02124066 0,18862359 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,02183198 0,19312907 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,02183198 0,19238911 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,02183198 0,1916548 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,02183198 0,19092607 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,02183198 0,19020287 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02183198 0,18948512 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,02183198 0,18877277 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,02183198 0,18806576 ! sleep GO:0030431 11 5 0,000 0,02183198 0,18736402 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,02183198 0,1866675 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,02183198 0,18597614 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,02183198 0,18528988 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,02183198 0,18460867 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,02183198 0,18393244 ! tongue development GO:0043586 6 5 0,000 0,02183198 0,18326116 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,02183198 0,18259475 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02183198 0,18193318 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,02183198 0,18127638 ! cobalt ion transport GO:0006824 9 5 0,000 0,02183198 0,18062431 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,02183198 0,17997691 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,02183198 0,17933413 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,02183198 0,17869593 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,02183198 0,17806226 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,02183198 0,17743306 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,02183198 0,1768083 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,02183198 0,17618792 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,02183198 0,17557188 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,02183198 0,17496013 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02183198 0,17435263 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02183198 0,17374933 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,02183198 0,1731502 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,02183198 0,17255518 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02183198 0,17196424 ! malate metabolic process GO:0006108 7 5 0,000 0,02183198 0,17137733 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,02183198 0,17079441 ! behavioral response to pain GO:0048266 7 5 0,000 0,02183198 0,17021545 ! clathrin coat assembly GO:0048268 11 5 0,000 0,02183198 0,1696404 ! phototransduction, visible light GO:0007603 6 5 0,000 0,02183198 0,16906922 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02183198 0,16850187 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,02183198 0,16793832 ! mating behavior GO:0007617 6 5 0,000 0,02183198 0,16737852 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02183198 0,16682245 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,02183198 0,16627006 ! rhythmic behavior GO:0007622 12 5 0,000 0,02183198 0,16572131 ! copulation GO:0007620 7 5 0,000 0,02183198 0,16517617 ! glial cell fate commitment GO:0021781 12 5 0,000 0,02183198 0,16463461 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,02183198 0,16409659 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,02183198 0,16356208 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,02183198 0,16303103 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,02183198 0,16250342 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,02183198 0,16197922 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,02183198 0,16145838 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,02183198 0,16094089 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02183198 0,1604267 ! response to protozoan GO:0001562 9 5 0,000 0,02183198 0,15991579 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,02183198 0,15940812 ! lymph vessel development GO:0001945 7 5 0,000 0,02183198 0,15890366 ! endochondral ossification GO:0001958 12 5 0,000 0,02183198 0,15840239 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,02183198 0,15790427 ! parathyroid gland development GO:0060017 8 5 0,000 0,02183198 0,15740927 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,02183198 0,15691737 ! anagen GO:0042640 6 5 0,000 0,02183198 0,15642853 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,02183198 0,15594272 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,02183198 0,15545993 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,02183198 0,15498011 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,02183198 0,15450325 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,02183198 0,15402932 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,02183198 0,15355828 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,02183198 0,15309011 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,02183198 0,15262479 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,02183198 0,15216229 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,02183198 0,15170259 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,02183198 0,15124565 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,02183198 0,15079146 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,02183198 0,15033999 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,02183198 0,14989122 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,02183198 0,14944511 ! ovulation GO:0030728 6 5 0,000 0,02183198 0,14900165 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,02183198 0,14856082 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,02183198 0,14812259 GO:0030033|microvillus assembly, ! response to pH GO:0009268 9 5 0,000 0,02183198 0,14768693 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,02183198 0,14725383 ! proline biosynthetic process GO:0006561 6 5 0,000 0,02183198 0,14682327 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02183198 0,14639521 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,02183198 0,14596964 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02183198 0,14554654 ! polyol catabolic process GO:0046174 7 5 0,000 0,02183198 0,14512589 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02183198 0,14470766 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02183198 0,14429183 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02183198 0,14387839 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,02183198 0,14346731 ! nerve growth factor processing GO:0032455 7 5 0,000 0,02183198 0,14305857 ! urea metabolic process GO:0019627 6 5 0,000 0,02183198 0,14265215 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,02183198 0,14224804 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02183198 0,14184621 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,02183198 0,14144664 ! neutrophil activation GO:0042119 5 5 0,000 0,02183198 0,14104932 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,02183198 0,14065422 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,02183198 0,14026133 ! response to food GO:0032094 5 5 0,000 0,02183198 0,13987063 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,02183198 0,1394821 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02183198 0,13909573 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,02183198 0,13871148 ! forebrain neuron development GO:0021884 7 5 0,000 0,02183198 0,13832936 ! melanosome organization GO:0032438 7 5 0,000 0,02183198 0,13794933 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,02183198 0,13757139 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02183198 0,13719551 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,02183198 0,13682168 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02183198 0,13644988 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,02183198 0,1360801 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,02183198 0,13571232 ! nucleoside transport GO:0015858 6 5 0,000 0,02183198 0,13534652 ! nucleoside salvage GO:0043174 7 5 0,000 0,02183198 0,13498268 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,02183198 0,1346208 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02183198 0,13426085 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,02183198 0,13390282 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,02183198 0,13354669 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02183198 0,13319246 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,02183198 0,1328401 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02183198 0,1324896 ! depyrimidination GO:0045008 8 5 0,000 0,02183198 0,13214094 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,02183198 0,13179411 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,02183198 0,1314491 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,02183198 0,13110589 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02183198 0,13076447 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,02183198 0,13042482 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,02183198 0,13008694 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,02183198 0,12975079 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,02183198 0,12941638 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,02183198 0,12908369 ! monocyte differentiation GO:0030224 8 5 0,000 0,02183198 0,12875271 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,02183198 0,12842342 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02183198 0,12809581 ! centrosome duplication GO:0051298 5 5 0,000 0,02183198 0,12776987 ! response to UV-C GO:0010225 6 5 0,000 0,02183198 0,12744558 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,02183198 0,12712293 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,02183198 0,12680191 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,02183198 0,12648251 ! regulation of dendrite development GO:0050773 12 5 0,000 0,02183198 0,12616472 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,02183198 0,12584851 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,02183198 0,12553389 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,02183198 0,12522084 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,02183198 0,12490935 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,02183198 0,1245994 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,02183198 0,12429098 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,02183198 0,12398409 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,02183198 0,12367871 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02183198 0,12337483 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,02183198 0,12307244 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02183198 0,12277153 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02183198 0,12247209 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,02183198 0,12217411 ! neural tube patterning GO:0021532 6 5 0,000 0,02183198 0,12187757 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,02183198 0,12158246 ! histone demethylation GO:0016577 9 5 0,000 0,02183198 0,12128879 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02183198 0,12099652 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02183198 0,12070567 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,02183198 0,1204162 ! enteric nervous system development GO:0048484 8 5 0,000 0,02183198 0,12012813 ! establishment of planar polarity GO:0001736 6 5 0,000 0,02183198 0,11984143 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,02183198 0,11955609 ! transcription termination GO:0006353 8 5 0,000 0,02183198 0,11927211 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,02183198 0,11898947 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,02183198 0,11870817 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,02183198 0,1184282 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,02183198 0,11814955 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,02183198 0,1178722 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02183198 0,11759615 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02183198 0,1173214 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,02183198 0,11704792 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,02183198 0,11677571 ! apical protein localization GO:0045176 6 5 0,000 0,02183198 0,11650477 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,02183198 0,11623509 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,02183198 0,11596664 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02183198 0,11569944 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02183198 0,11543346 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,02183198 0,11516871 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,02183198 0,11490517 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,02183198 0,11464282 ! glial cell migration GO:0008347 10 5 0,000 0,02183198 0,11438168 ! determination of adult lifespan GO:0008340 8 5 0,000 0,02183198 0,11412172 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,02183198 0,11386294 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02183198 0,11360533 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02183198 0,11334889 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,02183198 0,1130936 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,02183198 0,11283945 ! neural plate development GO:0001840 6 5 0,000 0,02183198 0,11258645 ! regulation of sensory perception GO:0051931 6 5 0,000 0,02183198 0,11233458 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,02183198 0,11208383 ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,02183198 0,1118342 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,02183198 0,11158568 ! sensory cilium assembly GO:0035058 6 5 0,000 0,02183198 0,11133826 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,02183198 0,11109194 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02183198 0,1108467 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,02183198 0,11060255 ! spindle assembly GO:0051225 5 5 0,000 0,02183198 0,11035947 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,02183198 0,11011745 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,02183198 0,10987649 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,02183198 0,10963659 ! organ regeneration GO:0031100 7 5 0,000 0,02183198 0,10939773 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,02183198 0,10915991 ! carnitine metabolic process GO:0009437 5 5 0,000 0,02183198 0,10892312 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,02183198 0,10868735 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,02183198 0,10845261 GO:0055081|anion homeostasis, ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,02202809 0,10919098 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,02282751 0,11291029 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,02282751 0,11266799 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,0236388 0,11642238 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,0236388 0,11617361 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,0236388 0,11592591 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 0,02529652 0,12379146 ! tRNA transcription GO:0009304 11 6 0,000 0,02614158 0,1276553 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,02614158 0,12738484 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,02614158 0,12711553 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,02614158 0,12684735 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02614158 0,1265803 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,02614158 0,12631438 ! regulation of helicase activity GO:0051095 11 6 0,000 0,02614158 0,12604957 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,02614158 0,12578587 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,02614158 0,12552327 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,02614158 0,12526176 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,02614158 0,12500134 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,02614158 0,124742 ! prostate gland development GO:0030850 9 6 0,000 0,02614158 0,12448374 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,02614158 0,12422654 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,02614158 0,1239704 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,02614158 0,12371532 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,02614158 0,12346128 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,02614158 0,12320829 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,02614158 0,12295633 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,02614158 0,1227054 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,02614158 0,12245549 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,02614158 0,1222066 ! neuron adhesion GO:0007158 9 6 0,000 0,02614158 0,12195871 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,02614158 0,12171183 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,02614158 0,12146595 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,02614158 0,12122106 ! signal peptide processing GO:0006465 8 6 0,000 0,02614158 0,12097715 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,02614158 0,12073423 ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,02614158 0,12049227 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,02614158 0,12025129 ! opsonization GO:0008228 8 6 0,000 0,02614158 0,12001127 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,02614158 0,1197722 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,02614158 0,11953409 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,02614158 0,11929691 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,02614158 0,11906068 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,02614158 0,11882539 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02614158 0,11859102 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,02614158 0,11835757 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,02614158 0,11812504 ! mechanosensory behavior GO:0007638 8 6 0,000 0,02614158 0,11789342 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,02614158 0,11766271 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,02614158 0,1174329 ! response to interferon-gamma GO:0034341 12 6 0,000 0,02614158 0,11720399 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,02614158 0,11697596 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,02614158 0,11674882 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02614158 0,11652257 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,02614158 0,11629719 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,02614158 0,11607267 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,02614158 0,11584903 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,02614158 0,11562624 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,02614158 0,11540431 ! thymic T cell selection GO:0045061 12 6 0,000 0,02614158 0,11518323 ! protein lipoylation GO:0009249 10 6 0,000 0,02614158 0,11496299 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,02614158 0,1147436 ! pigment granule organization GO:0048753 11 6 0,000 0,02614158 0,11452504 ! drug transport GO:0015893 6 6 0,000 0,02614158 0,11430731 ! cysteine metabolic process GO:0006534 7 6 0,000 0,02614158 0,11409041 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,02614158 0,11387433 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,02614158 0,11365906 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02614158 0,11344461 ! histidine metabolic process GO:0006547 6 6 0,000 0,02614158 0,11323097 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,02614158 0,11301813 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,02614158 0,11280609 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,02614158 0,11259484 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,02614158 0,11238438 ! adenohypophysis development GO:0021984 10 6 0,000 0,02614158 0,11217471 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,02614158 0,11196582 ! hyperosmotic response GO:0006972 8 6 0,000 0,02614158 0,1117577 ! microtubule nucleation GO:0007020 10 6 0,000 0,02614158 0,11155036 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,02614158 0,11134379 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,02614158 0,11113798 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,02614158 0,11093292 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,02614158 0,11072863 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,02614158 0,11052508 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,02614158 0,11032228 ! response to dietary excess GO:0002021 7 6 0,000 0,02614158 0,11012023 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,02614158 0,10991891 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,02614158 0,10971833 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,02614158 0,10951848 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,02614158 0,10931935 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,02614158 0,10912095 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,02614158 0,10892327 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02614158 0,1087263 ! neuron apoptosis GO:0051402 8 6 0,000 0,02614158 0,10853004 ! organic alcohol transport GO:0015850 9 6 0,000 0,02614158 0,1083345 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,02614158 0,10813965 ! T cell mediated immunity GO:0002456 12 6 0,000 0,02614158 0,1079455 ! male sex determination GO:0030238 9 6 0,000 0,02614158 0,10775205 ! carnitine transport GO:0015879 8 6 0,000 0,02614158 0,10755929 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,02614158 0,10736722 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,02614158 0,10717584 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02614158 0,10698513 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,02614158 0,10679511 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,02614158 0,10660575 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,02614158 0,10641707 ! parturition GO:0007567 12 6 0,000 0,02614158 0,10622905 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,02614158 0,1060417 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,02614158 0,10585501 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,02614158 0,10566897 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,02614158 0,10548359 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,02614158 0,10529885 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,02614158 0,10511476 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,02614158 0,10493132 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,02614158 0,10474851 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,02614158 0,10456634 ! macrophage differentiation GO:0030225 10 6 0,000 0,02614158 0,1043848 ! astrocyte development GO:0014002 14 6 0,000 0,02614158 0,10420389 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,02614158 0,10402361 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,02614158 0,10384395 ! interaction with symbiont GO:0051702 8 6 0,000 0,02614158 0,1036649 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,02614158 0,10348648 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02614158 0,10330867 ! eating behavior GO:0042755 6 6 0,000 0,02614158 0,10313147 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,02614158 0,10295487 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,02614158 0,10277888 ! response to copper ion GO:0046688 9 6 0,000 0,02614158 0,10260349 ! DNA topological change GO:0006265 8 6 0,000 0,02614158 0,1024287 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,02614158 0,1022545 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,02614158 0,10208089 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,02614158 0,10190787 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02614158 0,10173544 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02614158 0,10156359 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,02614158 0,10139232 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,02614158 0,10122162 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,02614158 0,1010515 ! gas homeostasis GO:0033483 11 6 0,000 0,02614158 0,10088195 ! hair follicle maturation GO:0048820 7 6 0,000 0,02614158 0,10071297 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,02614158 0,10054456 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,02614158 0,1003767 ! Schwann cell development GO:0014044 14 6 0,000 0,02614158 0,10020941 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,02614158 0,10004267 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,02614158 0,09987649 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02614158 0,09971085 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,02614158 0,09954577 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,02614158 0,09938123 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,02614158 0,09921724 ! histone ubiquitination GO:0016574 7 6 0,000 0,02614158 0,09905378 ! regulation of meiosis GO:0040020 10 6 0,000 0,02614158 0,09889086 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,02614158 0,09872848 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,02614158 0,09856663 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,02614158 0,09840531 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,02614158 0,09824452 ! membrane to membrane docking GO:0022614 12 6 0,000 0,02614158 0,09808425 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,02614158 0,0979245 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,02614158 0,09776528 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,02614158 0,09760657 ! receptor internalization GO:0031623 9 6 0,000 0,02614158 0,09744837 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,02614158 0,09729069 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,02614158 0,09713351 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02614158 0,09697685 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,02614158 0,09682068 ! protein deubiquitination GO:0016579 8 6 0,000 0,02614158 0,09666502 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,02614158 0,09650986 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,02614158 0,0963552 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,02614158 0,09620103 ! axonal fasciculation GO:0007413 9 6 0,000 0,02614158 0,09604736 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,02614158 0,09589417 ! thiamin metabolic process GO:0006772 6 6 0,000 0,02614158 0,09574147 ! midbrain development GO:0030901 6 6 0,000 0,02614158 0,09558926 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,02614158 0,09543753 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02614158 0,09528628 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,02614158 0,09513551 ! progesterone metabolic process GO:0042448 8 6 0,000 0,02614158 0,09498522 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,02614158 0,0948354 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,02614158 0,09468605 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,02614158 0,09453718 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,02614158 0,09438877 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,02614158 0,09424082 ! adult feeding behavior GO:0008343 6 6 0,000 0,02614158 0,09409334 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,02614158 0,09394632 ! blastocyst growth GO:0001832 15 6 0,000 0,02614158 0,09379976 ! pigment granule transport GO:0051904 12 6 0,000 0,02614158 0,09365365 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,02614158 0,093508 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,02614158 0,0933628 ! catecholamine transport GO:0051937 7 6 0,000 0,02614158 0,09321805 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02614158 0,09307375 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,02614158 0,0929299 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,02614158 0,09278649 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,02614158 0,09264352 ! protein prenylation GO:0018342 10 6 0,000 0,02614158 0,09250099 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02614158 0,0923589 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,02614158 0,09221725 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,02614158 0,09207603 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,02614158 0,09193524 ! chromosome segregation GO:0007059 83 57 1,000 0,02614271 0,09179882 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 0,02614271 0,09165889 ! gonad development GO:0008406 79 57 1,000 0,02614271 0,09151937 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 0,0270003 0,09437796 ! activation of MAPK activity GO:0000187 84 59 1,000 0,02786919 0,09726727 ! lung development GO:0030324 94 59 1,000 0,02786919 0,09711989 ! myeloid cell differentiation GO:0030099 85 59 1,000 0,02786919 0,09697297 ! fertilization GO:0009566 68 60 1,000 0,02874925 0,09988409 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,02874925 0,09973344 ! cell-matrix adhesion GO:0007160 114 61 1,000 0,02964037 0,10266996 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,03043245 0,10525508 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,03043245 0,10509704 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,03043245 0,10493947 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,03043245 0,10478238 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,03043245 0,10462575 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03043245 0,10446959 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,03043245 0,1043139 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03043245 0,10415867 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,03043245 0,1040039 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,03043245 0,10384959 ! reproductive behavior GO:0019098 12 7 0,000 0,03043245 0,10369574 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,03043245 0,10354235 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,03043245 0,1033894 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,03043245 0,10323691 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,03043245 0,10308487 ! oligopeptide transport GO:0006857 11 7 0,000 0,03043245 0,10293327 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,03043245 0,10278212 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,03043245 0,10263142 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,03043245 0,10248115 ! RNA methylation GO:0001510 11 7 0,000 0,03043245 0,10233133 ! pericardium development GO:0060039 8 7 0,000 0,03043245 0,10218194 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,03043245 0,10203298 ! fibril organization GO:0043206 13 7 0,000 0,03043245 0,10188446 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03043245 0,10173638 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,03043245 0,10158872 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,03043245 0,10144149 ! lipoprotein transport GO:0042953 9 7 0,000 0,03043245 0,10129468 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,03043245 0,1011483 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03043245 0,10100235 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03043245 0,10085681 ! estrogen metabolic process GO:0008210 14 7 0,000 0,03043245 0,10071169 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,03043245 0,10056699 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,03043245 0,10042271 ! chemosensory behavior GO:0007635 9 7 0,000 0,03043245 0,10027883 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,03043245 0,10013537 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,03043245 0,09999232 ! leukocyte degranulation GO:0043299 10 7 0,000 0,03043245 0,09984968 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,03043245 0,09970745 ! reflex GO:0060004 12 7 0,000 0,03043245 0,09956561 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03043245 0,09942419 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,03043245 0,09928316 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03043245 0,09914253 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,03043245 0,0990023 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,03043245 0,09886247 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03043245 0,09872303 ! spinal cord patterning GO:0021511 7 7 0,000 0,03043245 0,09858398 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,03043245 0,09844533 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,03043245 0,09830706 ! adrenal gland development GO:0030325 17 7 0,000 0,03043245 0,09816918 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,03043245 0,09803169 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,03043245 0,09789458 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,03043245 0,09775786 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,03043245 0,09762152 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,03043245 0,09748555 ! endosome organization GO:0007032 10 7 0,000 0,03043245 0,09734997 ! thyroid hormone generation GO:0006590 11 7 0,000 0,03043245 0,09721476 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,03043245 0,09707993 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,03043245 0,09694547 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,03043245 0,09681138 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03043245 0,09667766 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,03043245 0,09654431 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03043245 0,09641133 ! galactose metabolic process GO:0006012 10 7 0,000 0,03043245 0,09627872 ! vesicle fusion GO:0006906 15 7 0,000 0,03043245 0,09614647 ! intracellular pH reduction GO:0051452 10 7 0,000 0,03043245 0,09601458 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,03043245 0,09588305 ! organ growth GO:0035265 11 7 0,000 0,03043245 0,09575188 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,03043245 0,09562107 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,03043245 0,09549062 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,03043245 0,09536053 ! retinol metabolic process GO:0042572 9 7 0,000 0,03043245 0,09523078 ! behavioral fear response GO:0001662 13 7 0,000 0,03043245 0,09510139 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,03043245 0,09497236 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,03043245 0,09484367 ! rRNA modification GO:0000154 12 7 0,000 0,03043245 0,09471533 ! protein heterooligomerization GO:0051291 10 7 0,000 0,03043245 0,09458733 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03043245 0,09445969 ! response to UV-B GO:0010224 11 7 0,000 0,03043245 0,09433238 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,03043245 0,09420542 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,03043245 0,0940788 ! intermediate filament organization GO:0045109 11 7 0,000 0,03043245 0,09395252 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,03043245 0,09382658 ! fibrinolysis GO:0042730 9 7 0,000 0,03043245 0,09370097 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,03043245 0,0935757 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,03043245 0,09345077 ! B cell lineage commitment GO:0002326 17 7 0,000 0,03043245 0,09332617 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,03043245 0,0932019 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,03043245 0,09307796 ! response to tropane GO:0014073 13 7 0,000 0,03043245 0,09295435 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,03043245 0,09283107 ! melanosome localization GO:0032400 10 7 0,000 0,03043245 0,09270811 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,03043245 0,09258548 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,03043245 0,09246318 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,03043245 0,0923412 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,03043245 0,09221953 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,03043245 0,09209819 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,03043245 0,09197717 ! mast cell activation GO:0045576 9 7 0,000 0,03043245 0,09185647 ! multicellular organismal aging GO:0010259 11 7 0,000 0,03043245 0,09173608 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,03043245 0,091616 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,03043245 0,09149624 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,03043245 0,0913768 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,03043245 0,09125766 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,03043245 0,09113884 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,03043245 0,09102032 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,03043245 0,09090211 ! T cell lineage commitment GO:0002360 12 7 0,000 0,03043245 0,09078421 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,03043245 0,09066661 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,03043245 0,09054932 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,03043245 0,09043233 ! regulation of lipid transport GO:0032368 13 7 0,000 0,03043245 0,09031565 ! response to tumor cell GO:0002347 12 7 0,000 0,03043245 0,09019926 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,03043245 0,09008317 ! neuroblast proliferation GO:0007405 13 7 0,000 0,03043245 0,08996739 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,03043245 0,0898519 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,03043245 0,0897367 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,03043245 0,0896218 ! diuresis GO:0030146 12 7 0,000 0,03043245 0,0895072 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,03043245 0,08939288 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,03043245 0,08927886 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03043245 0,08916513 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,03043245 0,08905169 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03043245 0,08893853 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03043245 0,08882567 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03043245 0,08871309 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,03043245 0,08860079 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,03043245 0,08848878 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,03043245 0,08837705 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,03043245 0,08826561 ! lymph node development GO:0048535 9 7 0,000 0,03043245 0,08815444 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,03043245 0,08804356 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,03043245 0,08793295 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03043245 0,08782262 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,03043245 0,08771256 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,03043245 0,08760279 ! ATP catabolic process GO:0006200 10 7 0,000 0,03043245 0,08749328 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,03043245 0,08738405 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,03043245 0,0872751 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,03043245 0,08716641 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,03043245 0,08705799 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,03043245 0,08694985 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,03043245 0,08684197 ! muscle adaptation GO:0043500 12 7 0,000 0,03043245 0,08673436 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,03043245 0,08662701 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,03043245 0,08651993 ! retina homeostasis GO:0001895 9 7 0,000 0,03043245 0,08641312 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,03043245 0,08630657 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,03043245 0,08620028 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,03043245 0,08609425 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,03043245 0,08598848 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,03043245 0,08588298 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,03043245 0,08577773 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03043245 0,08567274 ! negative regulation of cell growth GO:0030308 106 62 1,000 0,03054245 0,08587729 ! respiratory tube development GO:0030323 99 62 1,000 0,03054245 0,08577244 ! regulation of lipase activity GO:0060191 109 63 1,000 0,03145536 0,08822845 ! negative regulation of cell size GO:0045792 108 64 1,000 0,03237901 0,09070855 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 1,000 0,03237901 0,0905982 ! respiratory system development GO:0060541 100 64 1,000 0,03237901 0,09048812 ! adaptive immune response GO:0002250 94 64 1,000 0,03237901 0,0903783 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 1,000 0,03331328 0,09287337 ! protein oligomerization GO:0051259 100 65 1,000 0,03331328 0,09276094 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,03425805 0,09527633 ! axon guidance GO:0007411 99 66 1,000 0,03425805 0,09516126 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,03470465 0,09628551 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,03470465 0,0961695 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,03470465 0,09605378 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,03470465 0,09593833 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,03470465 0,09582315 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,03470465 0,09570826 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,03470465 0,09559364 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,03470465 0,09547929 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,03470465 0,09536522 ! phosphate transport GO:0006817 10 8 0,000 0,03470465 0,09525142 ! N-glycan processing GO:0006491 12 8 0,000 0,03470465 0,09513789 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,03470465 0,09502463 ! UTP metabolic process GO:0046051 8 8 0,000 0,03470465 0,09491164 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,03470465 0,09479892 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,03470465 0,09468646 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,03470465 0,09457427 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,03470465 0,09446235 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03470465 0,09435069 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,03470465 0,0942393 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,03470465 0,09412817 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,03470465 0,0940173 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,03470465 0,09390669 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03470465 0,09379634 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,03470465 0,09368625 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,03470465 0,09357642 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,03470465 0,09346685 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,03470465 0,09335753 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,03470465 0,09324847 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,03470465 0,09313966 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,03470465 0,0930311 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,03470465 0,0929228 ! astrocyte differentiation GO:0048708 16 8 0,000 0,03470465 0,09281475 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,03470465 0,09270695 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,03470465 0,09259941 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,03470465 0,09249211 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,03470465 0,09238505 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,03470465 0,09227825 ! melanin metabolic process GO:0006582 12 8 0,000 0,03470465 0,09217169 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,03470465 0,09206538 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03470465 0,09195932 ! macrophage activation GO:0042116 12 8 0,000 0,03470465 0,0918535 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,03470465 0,09174792 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,03470465 0,09164258 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,03470465 0,09153749 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,03470465 0,09143263 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,03470465 0,09132802 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,03470465 0,09122364 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,03470465 0,09111951 ! ruffle organization GO:0031529 11 8 0,000 0,03470465 0,09101561 ! osteoblast development GO:0002076 13 8 0,000 0,03470465 0,09091194 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,03470465 0,09080852 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,03470465 0,09070533 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,03470465 0,09060237 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,03470465 0,09049965 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,03470465 0,09039715 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,03470465 0,0902949 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,03470465 0,09019287 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,03470465 0,09009107 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,03470465 0,0899895 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,03470465 0,08988816 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,03470465 0,08978705 ! oligodendrocyte development GO:0014003 8 8 0,000 0,03470465 0,08968617 ! segment specification GO:0007379 10 8 0,000 0,03470465 0,08958551 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,03470465 0,08948508 ! cellular extravasation GO:0045123 11 8 0,000 0,03470465 0,08938487 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,03470465 0,08928489 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,03470465 0,08918513 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,03470465 0,08908559 ! snRNA metabolic process GO:0016073 10 8 0,000 0,03470465 0,08898627 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,03470465 0,08888718 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,03470465 0,08878831 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,03470465 0,08868965 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,03470465 0,08859122 ! nucleosome disassembly GO:0006337 12 8 0,000 0,03470465 0,088493 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,03470465 0,088395 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,03470465 0,08829722 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,03470465 0,08819965 ! icosanoid secretion GO:0032309 12 8 0,000 0,03470465 0,0881023 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,03470465 0,08800517 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03470465 0,08790825 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,03470465 0,08781154 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,03470465 0,08771504 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,03470465 0,08761876 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,03470465 0,08752268 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,03470465 0,08742682 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,03470465 0,08733117 ! sterol catabolic process GO:0016127 9 8 0,000 0,03470465 0,08723572 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,03470465 0,08714049 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,03470465 0,08704546 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,03470465 0,08695064 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,03470465 0,08685603 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03470465 0,08676162 ! prophase GO:0051324 11 8 0,000 0,03470465 0,08666741 ! S phase GO:0051320 8 8 0,000 0,03470465 0,08657341 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,03470465 0,08647962 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,03470465 0,08638603 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,03470465 0,08629264 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,03470465 0,08619945 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,03470465 0,08610646 ! hormone catabolic process GO:0042447 13 8 0,000 0,03470465 0,08601367 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,03470465 0,08592108 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,03470465 0,0858287 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,03470465 0,08573651 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,03470465 0,08564451 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,03470465 0,08555272 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,03470465 0,08546112 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,03470465 0,08536972 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03470465 0,08527851 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,03470465 0,0851875 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,03470465 0,08509668 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,03470465 0,08500606 ! lamellipodium assembly GO:0030032 9 8 0,000 0,03470465 0,08491562 ! regulation of embryonic development GO:0045995 16 8 0,000 0,03470465 0,08482539 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03470465 0,08473534 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,03470465 0,08464548 ! development of primary sexual characteristics GO:0045137 92 68 1,000 0,03617872 0,0881473 ! activation of protein kinase activity GO:0032147 102 69 1,000 0,03715439 0,09042867 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 1,000 0,03814014 0,09272973 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,03895827 0,09461881 ! regulation of developmental growth GO:0048638 13 9 0,000 0,03895827 0,094519 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,03895827 0,0944194 ! telencephalon cell migration GO:0022029 16 9 0,000 0,03895827 0,09432001 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,03895827 0,09422083 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,03895827 0,09412186 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,03895827 0,0940231 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,03895827 0,09392454 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03895827 0,09382619 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,03895827 0,09372805 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,03895827 0,09363011 ! GTP metabolic process GO:0046039 9 9 0,000 0,03895827 0,09353237 ! elastic fiber assembly GO:0048251 13 9 0,000 0,03895827 0,09343484 ! social behavior GO:0035176 14 9 0,000 0,03895827 0,09333751 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,03895827 0,09324039 ! artery development GO:0060840 19 9 0,000 0,03895827 0,09314346 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,03895827 0,09304674 ! regulation of glycolysis GO:0006110 15 9 0,000 0,03895827 0,09295022 ! response to pain GO:0048265 16 9 0,000 0,03895827 0,0928539 ! protein complex disassembly GO:0043241 17 9 0,000 0,03895827 0,09275778 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,03895827 0,09266185 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,03895827 0,09256613 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,03895827 0,0924706 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,03895827 0,09237527 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,03895827 0,09228014 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,03895827 0,0921852 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,03895827 0,09209045 ! ventral spinal cord development GO:0021517 11 9 0,000 0,03895827 0,09199591 ! protein targeting to ER GO:0045047 19 9 0,000 0,03895827 0,09190155 ! T cell selection GO:0045058 18 9 0,000 0,03895827 0,09180739 ! endoderm development GO:0007492 12 9 0,000 0,03895827 0,09171342 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,03895827 0,09161964 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,03895827 0,09152606 ! arginine catabolic process GO:0006527 10 9 0,000 0,03895827 0,09143266 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,03895827 0,09133946 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,03895827 0,09124645 GO:0010833|telomere maintenance via telomere lengthening, ! V(D)J recombination GO:0033151 12 9 0,000 0,03895827 0,09115362 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,03895827 0,09106099 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,03895827 0,09096854 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,03895827 0,09087628 ! mannose metabolic process GO:0006013 9 9 0,000 0,03895827 0,09078421 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,03895827 0,09069232 ! receptor clustering GO:0043113 15 9 0,000 0,03895827 0,09060062 ! epithelial cell development GO:0002064 10 9 0,000 0,03895827 0,0905091 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,03895827 0,09041777 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,03895827 0,09032662 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,03895827 0,09023566 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,03895827 0,09014488 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,03895827 0,09005428 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,03895827 0,08996387 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,03895827 0,08987363 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,03895827 0,08978358 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,03895827 0,08969371 ! blastoderm segmentation GO:0007350 11 9 0,000 0,03895827 0,08960401 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,03895827 0,0895145 ! DNA ligation GO:0006266 14 9 0,000 0,03895827 0,08942516 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,03895827 0,089336 ! response to amine stimulus GO:0014075 13 9 0,000 0,03895827 0,08924702 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,03895827 0,08915822 ! erythrocyte development GO:0048821 11 9 0,000 0,03895827 0,08906959 ! renal water homeostasis GO:0003091 14 9 0,000 0,03895827 0,08898114 ! postreplication repair GO:0006301 11 9 0,000 0,03895827 0,08889287 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,03895827 0,08880477 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,03895827 0,08871684 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,03895827 0,08862909 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,03895827 0,08854151 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,03895827 0,08845411 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,03895827 0,08836688 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,03895827 0,08827981 ! acid secretion GO:0046717 14 9 0,000 0,03895827 0,08819292 ! musculoskeletal movement GO:0050881 11 9 0,000 0,03895827 0,08810621 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,03895827 0,08801966 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,03895827 0,08793328 ! purine base metabolic process GO:0006144 18 9 0,000 0,03895827 0,08784707 ! oocyte differentiation GO:0009994 12 9 0,000 0,03895827 0,08776103 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,03895827 0,08767516 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,03895827 0,08758945 ! spleen development GO:0048536 15 9 0,000 0,03895827 0,08750392 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,03895827 0,08741855 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,03895827 0,08733334 ! detection of calcium ion GO:0005513 13 9 0,000 0,03895827 0,08724831 ! blastocyst formation GO:0001825 12 9 0,000 0,03895827 0,08716344 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,03895827 0,08707873 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,03895827 0,08699419 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,03895827 0,08690981 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,03895827 0,08682559 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03895827 0,08674154 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,03895827 0,08665765 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,03895827 0,08657392 ! prepulse inhibition GO:0060134 14 9 0,000 0,03895827 0,08649036 ! embryonic placenta development GO:0001892 12 9 0,000 0,03895827 0,08640695 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,03895827 0,08632371 ! insulin secretion GO:0030073 17 9 0,000 0,03895827 0,08624063 ! sequestering of metal ion GO:0051238 11 9 0,000 0,03895827 0,0861577 ! response to nicotine GO:0035094 16 9 0,000 0,03895827 0,08607494 ! establishment of cell polarity GO:0030010 12 9 0,000 0,03895827 0,08599233 ! nucleus localization GO:0051647 15 9 0,000 0,03895827 0,08590989 ! regulation of synapse organization GO:0050807 12 9 0,000 0,03895827 0,0858276 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,03913587 0,08613637 ! muscle cell differentiation GO:0042692 104 71 1,000 0,03913587 0,08605402 ! response to hypoxia GO:0001666 132 72 1,000 0,04014148 0,0881809 ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,04014148 0,08809676 ! mitochondrion organization GO:0007005 104 73 1,000 0,04115685 0,09023905 ! response to oxygen levels GO:0070482 137 74 1,000 0,0421819 0,09239845 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,0421819 0,09231053 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,04319338 0,0944342 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,04319338 0,09434452 ! neuron fate specification GO:0048665 11 10 0,000 0,04319338 0,09425501 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,04319338 0,09416567 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,04319338 0,0940765 ! thyroid gland development GO:0030878 19 10 0,000 0,04319338 0,0939875 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,04319338 0,09389866 ! synapsis GO:0007129 13 10 0,000 0,04319338 0,09380999 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,04319338 0,09372149 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,04319338 0,09363316 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,04319338 0,09354499 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,04319338 0,09345699 ! sulfate transport GO:0008272 12 10 0,000 0,04319338 0,09336916 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,04319338 0,09328149 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,04319338 0,09319398 ! androgen metabolic process GO:0008209 13 10 0,000 0,04319338 0,09310664 ! phospholipid efflux GO:0033700 16 10 0,000 0,04319338 0,09301946 ! hippocampus development GO:0021766 19 10 0,000 0,04319338 0,09293244 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,04319338 0,09284559 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,04319338 0,0927589 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,04319338 0,09267237 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,04319338 0,092586 ! pathogenesis GO:0009405 13 10 0,000 0,04319338 0,0924998 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,04319338 0,09241375 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04319338 0,09232786 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,04319338 0,09224214 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,04319338 0,09215657 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,04319338 0,09207116 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,04319338 0,09198591 ! melanocyte differentiation GO:0030318 15 10 0,000 0,04319338 0,09190082 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,04319338 0,09181588 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,04319338 0,0917311 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04319338 0,09164648 ! response to X-ray GO:0010165 16 10 0,000 0,04319338 0,09156201 ! B cell proliferation GO:0042100 14 10 0,000 0,04319338 0,0914777 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,04319338 0,09139354 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,04319338 0,09130954 ! forebrain cell migration GO:0021885 17 10 0,000 0,04319338 0,0912257 ! lipid digestion GO:0044241 15 10 0,000 0,04319338 0,091142 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,04319338 0,09105846 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,04319338 0,09097508 ! UV protection GO:0009650 14 10 0,000 0,04319338 0,09089184 ! entry into host cell GO:0030260 20 10 0,000 0,04319338 0,09080876 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,04319338 0,09072583 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,04319338 0,09064305 ! negative regulation of ossification GO:0030279 19 10 0,000 0,04319338 0,09056042 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,04319338 0,09047794 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,04319338 0,09039562 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,04319338 0,09031344 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,04319338 0,09023141 ! response to dsRNA GO:0043331 18 10 0,000 0,04319338 0,09014953 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,04319338 0,0900678 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04319338 0,08998622 ! embryonic axis specification GO:0000578 12 10 0,000 0,04319338 0,08990478 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,04319338 0,08982349 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,04319338 0,08974235 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,04319338 0,08966136 ! cranial nerve development GO:0021545 12 10 0,000 0,04319338 0,08958051 ! fucose catabolic process GO:0019317 16 10 0,000 0,04319338 0,0894998 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,04319338 0,08941925 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,04319338 0,08933883 ! protein sumoylation GO:0016925 12 10 0,000 0,04319338 0,08925856 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,04319338 0,08917844 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04319338 0,08909846 ! zymogen activation GO:0031638 14 10 0,000 0,04319338 0,08901862 ! salivary gland development GO:0007431 22 10 0,000 0,04319338 0,08893893 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04319338 0,08885938 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,04319338 0,08877997 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,04319338 0,0887007 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,04319338 0,08862157 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,04319338 0,08854259 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04319338 0,08846374 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,04319338 0,08838504 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,04319338 0,08830647 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,04319338 0,08822805 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,04319338 0,08814976 ! detection of bacterium GO:0016045 10 10 0,000 0,04319338 0,08807162 ! embryonic gut development GO:0048566 11 10 0,000 0,04319338 0,08799361 ! activation of innate immune response GO:0002218 10 10 0,000 0,04319338 0,08791574 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,04319338 0,087838 ! developmental induction GO:0031128 13 10 0,000 0,04319338 0,08776041 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,04319338 0,08768295 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,04319338 0,08760563 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,04319338 0,08752844 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,04319338 0,08745139 ! negative regulation of growth GO:0045926 123 75 1,000 0,04321651 0,08742126 ! response to nutrient GO:0007584 104 75 1,000 0,04321651 0,08734444 ! amine biosynthetic process GO:0009309 97 76 1,000 0,04426058 0,08937606 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,04426058 0,08929766 ! cholesterol metabolic process GO:0008203 109 77 1,000 0,04531401 0,09134289 ! gland development GO:0048732 148 77 1,000 0,04531401 0,0912629 ! sex differentiation GO:0007548 105 77 1,000 0,04531401 0,09118306 ! regulation of DNA binding GO:0051101 119 77 1,000 0,04531401 0,09110335 ! positive regulation of protein modification process GO:0031401 107 78 1,000 0,04637671 0,09315846 ! rRNA transcription GO:0009303 17 11 0,000 0,04741008 0,09515112 ! respiratory burst GO:0045730 14 11 0,000 0,04741008 0,09506816 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,04741008 0,09498535 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,04741008 0,09490268 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,04741008 0,09482016 ! virus-host interaction GO:0019048 17 11 0,000 0,04741008 0,09473778 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,04741008 0,09465554 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,04741008 0,09457345 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,04741008 0,09449149 ! RNA polyadenylation GO:0043631 19 11 0,000 0,04741008 0,09440968 ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,04741008 0,09432801 ! mating GO:0007618 14 11 0,000 0,04741008 0,09424648 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,04741008 0,0941651 ! T cell proliferation GO:0042098 20 11 0,000 0,04741008 0,09408385 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,04741008 0,09400274 ! bone resorption GO:0045453 16 11 0,000 0,04741008 0,09392178 ! regulated secretory pathway GO:0045055 14 11 0,000 0,04741008 0,09384095 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,04741008 0,09376026 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,04741008 0,09367971 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,04741008 0,0935993 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,04741008 0,09351902 ! syncytium formation GO:0006949 15 11 0,000 0,04741008 0,09343889 ! plasma membrane organization GO:0007009 18 11 0,000 0,04741008 0,09335889 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,04741008 0,09327903 ! focal adhesion formation GO:0048041 24 11 0,000 0,04741008 0,0931993 ! mitotic spindle organization GO:0007052 15 11 0,000 0,04741008 0,09311971 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,04741008 0,09304026 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,04741008 0,09296094 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,04741008 0,09288176 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,04741008 0,09280271 ! adult heart development GO:0007512 11 11 0,000 0,04741008 0,0927238 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,04741008 0,09264502 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,04741008 0,09256637 ! temperature homeostasis GO:0001659 16 11 0,000 0,04741008 0,09248786 ! L-glutamate transport GO:0015813 16 11 0,000 0,04741008 0,09240948 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,04741008 0,09233123 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,04741008 0,09225312 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,04741008 0,09217513 ! stem cell development GO:0048864 29 11 0,000 0,04741008 0,09209728 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,04741008 0,09201956 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,04741008 0,09194198 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,04741008 0,09186452 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,04741008 0,09178719 ! vasoconstriction GO:0042310 15 11 0,000 0,04741008 0,09170999 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,04741008 0,09163293 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,04741008 0,09155599 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,04741008 0,09147918 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,04741008 0,0914025 ! ribosome assembly GO:0042255 13 11 0,000 0,04741008 0,09132595 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,04741008 0,09124953 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,04741008 0,09117323 ! chromatin silencing GO:0006342 19 11 0,000 0,04741008 0,09109706 ! nucleosome positioning GO:0016584 13 11 0,000 0,04741008 0,09102102 ! T cell homeostasis GO:0043029 20 11 0,000 0,04741008 0,09094511 ! regulation of isotype switching GO:0045191 19 11 0,000 0,04741008 0,09086932 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,04741008 0,09079366 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,04741008 0,09071812 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,04741008 0,09064271 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,04741008 0,09056743 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,04741008 0,09049227 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,04741008 0,09041723 ! male genitalia development GO:0030539 13 11 0,000 0,04741008 0,09034232 ! cholesterol efflux GO:0033344 19 11 0,000 0,04741008 0,09026754 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,04741008 0,09019287 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,04741008 0,09011833 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,04741008 0,09004392 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,04741008 0,08996962 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,04741008 0,08989545 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,04741008 0,0898214 ! defense response to fungus GO:0050832 12 11 0,000 0,04741008 0,08974748 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,04741008 0,08967367 ! lysogeny GO:0030069 18 11 0,000 0,04741008 0,08959999 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,04741008 0,08952642 ! acrosome reaction GO:0007340 13 11 0,000 0,04741008 0,08945298 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,04741008 0,08937966 ! vitamin metabolic process GO:0006766 103 81 1,000 0,04961938 0,09346812 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,04961938 0,09339163 GO:0002696|positive regulation of leukocyte activation, ! lactation GO:0007595 20 12 0,000 0,05160843 0,09705592 ! reproductive cellular process GO:0048610 14 12 0,000 0,05160843 0,09697663 ! tRNA modification GO:0006400 14 12 0,000 0,05160843 0,09689747 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,05160843 0,09681843 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,05160843 0,09673952 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,05160843 0,09666074 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,05160843 0,09658209 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,05160843 0,09650357 ! non-recombinational repair GO:0000726 19 12 0,000 0,05160843 0,09642518 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,05160843 0,09634691 ! peroxisomal transport GO:0043574 21 12 0,000 0,05160843 0,09626877 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,05160843 0,09619076 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,05160843 0,09611287 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,05160843 0,09603511 ! heart looping GO:0001947 15 12 0,000 0,05160843 0,09595747 ! palate development GO:0060021 15 12 0,000 0,05160843 0,09587996 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,05160843 0,09580258 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,05160843 0,09572532 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,05160843 0,09564818 ! arginine metabolic process GO:0006525 13 12 0,000 0,05160843 0,09557117 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,05160843 0,09549428 ! methionine metabolic process GO:0006555 13 12 0,000 0,05160843 0,09541752 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,05160843 0,09534088 ! Golgi organization GO:0007030 18 12 0,000 0,05160843 0,09526436 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,05160843 0,09518797 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,05160843 0,09511169 ! monoamine transport GO:0015844 13 12 0,000 0,05160843 0,09503554 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05160843 0,09495952 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,05160843 0,09488361 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,05160843 0,09480782 ! L-amino acid transport GO:0015807 20 12 0,000 0,05160843 0,09473216 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,05160843 0,09465661 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,05160843 0,09458119 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,05160843 0,09450589 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05160843 0,0944307 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,05160843 0,09435564 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,05160843 0,09428069 ! cerebellum development GO:0021549 13 12 0,000 0,05160843 0,09420587 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,05160843 0,09413116 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,05160843 0,09405657 ! histone acetylation GO:0016573 23 12 0,000 0,05160843 0,0939821 ! histone methylation GO:0016571 15 12 0,000 0,05160843 0,09390775 ! autonomic nervous system development GO:0048483 23 12 0,000 0,05160843 0,09383351 ! gland morphogenesis GO:0022612 23 12 0,000 0,05160843 0,0937594 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,05160843 0,09368539 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,05160843 0,09361151 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,05160843 0,09353774 ! response to gamma radiation GO:0010332 20 12 0,000 0,05160843 0,09346409 ! regulation of epidermis development GO:0045682 17 12 0,000 0,05160843 0,09339055 ! intestinal absorption GO:0050892 19 12 0,000 0,05160843 0,09331713 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,05160843 0,09324383 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,05160843 0,09317064 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,05160843 0,09309756 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,05160843 0,0930246 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,05160843 0,09295176 ! microspike assembly GO:0030035 23 12 0,000 0,05160843 0,09287903 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,05160843 0,09280641 ! regulation of cell adhesion GO:0030155 159 83 1,000 0,05182566 0,09312423 ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 0,05294186 0,09505564 ! sterol metabolic process GO:0016125 120 84 1,000 0,05294186 0,09498149 ! transcription initiation GO:0006352 118 85 1,000 0,05406663 0,09692382 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,05406663 0,09684833 ! regulation of membrane potential GO:0042391 128 85 1,000 0,05406663 0,09677296 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,05406663 0,09669771 ! cell cycle arrest GO:0007050 150 86 1,000 0,05519989 0,09864783 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,05578852 0,09962236 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,05578852 0,09954507 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,05578852 0,09946791 ! cGMP metabolic process GO:0046068 16 13 0,000 0,05578852 0,09939086 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,05578852 0,09931393 ! water transport GO:0006833 17 13 0,000 0,05578852 0,09923712 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,05578852 0,09916043 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,05578852 0,09908386 ! lipid localization GO:0010876 24 13 0,000 0,05578852 0,09900741 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,05578852 0,09893107 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,05578852 0,09885485 ! organelle fusion GO:0048284 28 13 0,000 0,05578852 0,09877875 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,05578852 0,09870277 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,05578852 0,0986269 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,05578852 0,09855115 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,05578852 0,09847552 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,05578852 0,0984 ! response to hexose stimulus GO:0009746 19 13 0,000 0,05578852 0,0983246 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,05578852 0,09824931 ! glutamate metabolic process GO:0006536 18 13 0,000 0,05578852 0,09817414 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,05578852 0,09809908 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,05578852 0,09802414 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,05578852 0,09794931 ! NAD metabolic process GO:0019674 21 13 0,000 0,05578852 0,0978746 ! exocrine system development GO:0035272 27 13 0,000 0,05578852 0,0978 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,05578852 0,09772551 ! bone mineralization GO:0030282 15 13 0,000 0,05578852 0,09765114 ! regulation of exocytosis GO:0017157 17 13 0,000 0,05578852 0,09757688 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,05578852 0,09750273 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,05578852 0,0974287 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,05578852 0,09735478 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,05578852 0,09728097 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,05578852 0,09720727 ! genitalia development GO:0048806 15 13 0,000 0,05578852 0,09713369 ! regulation of cellular pH GO:0030641 20 13 0,000 0,05578852 0,09706021 ! cellular pigmentation GO:0033059 24 13 0,000 0,05578852 0,09698685 ! tissue regeneration GO:0042246 21 13 0,000 0,05578852 0,09691359 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,05578852 0,09684045 ! cofactor transport GO:0051181 19 13 0,000 0,05578852 0,09676742 ! NADP metabolic process GO:0006739 18 13 0,000 0,05578852 0,0966945 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,05578852 0,09662169 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,05578852 0,09654898 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05578852 0,09647639 ! gas transport GO:0015669 18 13 0,000 0,05578852 0,09640391 ! heme biosynthetic process GO:0006783 20 13 0,000 0,05578852 0,09633153 ! regulation of axon extension GO:0030516 23 13 0,000 0,05578852 0,09625926 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,05578852 0,09618711 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,05578852 0,09611506 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,05578852 0,09604311 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,05578852 0,09597128 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,05578852 0,09589955 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,05578852 0,09582793 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,05634154 0,09670563 GO:0060538|skeletal muscle organ development, ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,05634154 0,09663352 ! reproductive developmental process GO:0003006 127 89 1,000 0,05864964 0,10051726 ! regulation of T cell activation GO:0050863 128 89 1,000 0,05864964 0,10044241 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,05995042 0,10259373 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,05995042 0,10251745 ! superoxide anion generation GO:0042554 18 14 0,000 0,05995042 0,10244129 ! neuron maturation GO:0042551 21 14 0,000 0,05995042 0,10236524 ! regulation of S phase GO:0033261 18 14 0,000 0,05995042 0,1022893 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,05995042 0,10221347 ! myotube differentiation GO:0014902 21 14 0,000 0,05995042 0,10213776 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,05995042 0,10206216 ! inositol metabolic process GO:0006020 20 14 0,000 0,05995042 0,10198667 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,05995042 0,10191129 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,05995042 0,10183602 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,05995042 0,10176087 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,05995042 0,10168582 ! gene silencing by RNA GO:0031047 20 14 0,000 0,05995042 0,10161089 ! response to cAMP GO:0051591 19 14 0,000 0,05995042 0,10153606 ! limbic system development GO:0021761 25 14 0,000 0,05995042 0,10146135 ! startle response GO:0001964 21 14 0,000 0,05995042 0,10138675 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,05995042 0,10131225 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,05995042 0,10123787 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,05995042 0,10116359 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,05995042 0,10108943 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,05995042 0,10101537 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,05995042 0,10094142 ! glycine metabolic process GO:0006544 22 14 0,000 0,05995042 0,10086758 ! pituitary gland development GO:0021983 23 14 0,000 0,05995042 0,10079384 ! cellular response to starvation GO:0009267 21 14 0,000 0,05995042 0,10072022 ! lysosomal transport GO:0007041 20 14 0,000 0,05995042 0,1006467 ! regulation of heart rate GO:0002027 23 14 0,000 0,05995042 0,10057329 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,05995042 0,10049998 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,05995042 0,10042679 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,05995042 0,10035369 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,05995042 0,10028071 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,05995042 0,10020783 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,05995042 0,10013506 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,05995042 0,10006239 ! axon cargo transport GO:0008088 27 14 0,000 0,05995042 0,09998983 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,05995042 0,09991737 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,05995042 0,09984502 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,05995042 0,09977278 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,05995042 0,09970063 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,05995042 0,0996286 ! mRNA splice site selection GO:0006376 26 14 0,000 0,05995042 0,09955666 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,05995042 0,09948483 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,05995042 0,0994131 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,05995042 0,09934148 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,05995042 0,09926996 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,05995042 0,09919854 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,05995042 0,09912723 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,05995042 0,09905602 ! muscle maintenance GO:0046716 19 14 0,000 0,05995042 0,09898491 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,05995042 0,0989139 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,05995042 0,09884299 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,05995042 0,09877219 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,05995042 0,09870149 ! cell killing GO:0001906 20 14 0,000 0,05995042 0,09863088 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,05995042 0,09856038 ! cilium assembly GO:0042384 20 14 0,000 0,05995042 0,09848998 ! peptide hormone secretion GO:0030072 23 14 0,000 0,05995042 0,09841968 ! DNA recombination GO:0006310 146 92 1,000 0,06217237 0,10199462 ! sulfur metabolic process GO:0006790 118 92 1,000 0,06217237 0,10192192 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,06336241 0,10379882 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,06336241 0,10372494 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,06409422 0,1048483 ! metencephalon development GO:0022037 19 15 0,000 0,06409422 0,10477378 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,06409422 0,10469936 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,06409422 0,10462506 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,06409422 0,10455085 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,06409422 0,10447676 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,06409422 0,10440277 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,06409422 0,10432888 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,06409422 0,1042551 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,06409422 0,10418142 ! bile acid metabolic process GO:0008206 22 15 0,000 0,06409422 0,10410784 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,06409422 0,10403437 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,06409422 0,10396101 ! adult walking behavior GO:0007628 25 15 0,000 0,06409422 0,10388774 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,06409422 0,10381458 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,06409422 0,10374152 ! myoblast differentiation GO:0045445 27 15 0,000 0,06409422 0,10366857 ! centrosome cycle GO:0007098 16 15 0,000 0,06409422 0,10359572 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,06409422 0,10352297 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,06409422 0,10345032 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,06409422 0,10337777 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,06409422 0,10330533 ! cerebral cortex development GO:0021987 29 15 0,000 0,06409422 0,10323299 ! response to osmotic stress GO:0006970 22 15 0,000 0,06409422 0,10316075 ! vesicle coating GO:0006901 25 15 0,000 0,06409422 0,10308861 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,06409422 0,10301657 ! DNA integration GO:0015074 22 15 0,000 0,06409422 0,10294463 ! peptide secretion GO:0002790 27 15 0,000 0,06409422 0,10287279 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,06409422 0,10280105 ! regulation of vasodilation GO:0042312 24 15 0,000 0,06409422 0,10272941 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,06409422 0,10265787 ! neuron recognition GO:0008038 22 15 0,000 0,06409422 0,10258643 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,06409422 0,10251509 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,06409422 0,10244385 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,06409422 0,10237271 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,06409422 0,10230167 ! biomineral formation GO:0031214 18 15 0,000 0,06409422 0,10223072 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,06409422 0,10215988 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,06409422 0,10208913 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,06409422 0,10201848 ! dopamine metabolic process GO:0042417 30 15 0,000 0,06409422 0,10194793 ! organic cation transport GO:0015695 19 15 0,000 0,06409422 0,10187747 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,06409422 0,10180712 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,06409422 0,10173686 ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,06409422 0,10166669 ! defense response to virus GO:0051607 27 15 0,000 0,06409422 0,10159663 ! peptide hormone processing GO:0016486 19 15 0,000 0,06409422 0,10152666 ! regulation of binding GO:0051098 151 95 1,000 0,06576564 0,10410253 ! regulation of response to external stimulus GO:0032101 139 96 1,000 0,06697865 0,10594973 ! protein amino acid glycosylation GO:0006486 134 97 1,000 0,06819915 0,10780621 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! protein secretion GO:0009306 27 16 0,000 0,06821999 0,10776509 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,06821999 0,10769112 ! hormone secretion GO:0046879 25 16 0,000 0,06821999 0,10761726 ! bone remodeling GO:0046849 24 16 0,000 0,06821999 0,1075435 ! endothelial cell migration GO:0043542 22 16 0,000 0,06821999 0,10746984 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,06821999 0,10739628 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,06821999 0,10732282 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,06821999 0,10724946 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,06821999 0,10717621 ! glial cell development GO:0021782 24 16 0,000 0,06821999 0,10710305 ! patterning of blood vessels GO:0001569 24 16 0,000 0,06821999 0,10702999 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,06821999 0,10695703 GO:0042744|hydrogen peroxide catabolic process, ! protein polyubiquitination GO:0000209 26 16 0,000 0,06821999 0,10688417 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,06821999 0,10681141 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,06821999 0,10673875 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,06821999 0,10666619 ! fructose metabolic process GO:0006000 20 16 0,000 0,06821999 0,10659373 ! regulation of protein binding GO:0043393 27 16 0,000 0,06821999 0,10652136 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,06821999 0,10644909 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,06821999 0,10637693 ! protein export from nucleus GO:0006611 24 16 0,000 0,06821999 0,10630485 ! negative regulation of immune response GO:0050777 28 16 0,000 0,06821999 0,10623288 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,06821999 0,10616101 ! DNA replication initiation GO:0006270 25 16 0,000 0,06821999 0,10608923 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,06821999 0,10601754 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,06821999 0,10594596 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,06821999 0,10587447 ! diencephalon development GO:0021536 25 16 0,000 0,06821999 0,10580308 ! oogenesis GO:0048477 23 16 0,000 0,06821999 0,10573178 ! neural crest cell migration GO:0001755 24 16 0,000 0,06821999 0,10566058 ! G1 phase GO:0051318 27 16 0,000 0,06821999 0,10558948 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,06821999 0,10551847 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,06821999 0,10544756 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,06821999 0,10537674 ! steroid catabolic process GO:0006706 22 16 0,000 0,06821999 0,10530602 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,06821999 0,10523539 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,06821999 0,10516486 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,06821999 0,10509442 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,06821999 0,10502407 ! sperm-egg recognition GO:0035036 16 16 0,000 0,06821999 0,10495382 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,06821999 0,10488367 ! nerve development GO:0021675 18 16 0,000 0,06821999 0,1048136 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,06821999 0,10474364 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,06821999 0,10467376 ! negative regulation of translation GO:0017148 22 16 0,000 0,06821999 0,10460398 ! extracellular structure organization GO:0043062 156 99 1,000 0,07066223 0,10827656 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 0,07066223 0,10820447 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,07190464 0,11003371 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,0723278 0,11060767 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,0723278 0,11053418 ! negative regulation of defense response GO:0031348 19 17 0,000 0,0723278 0,11046078 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,0723278 0,11038748 ! glycerol metabolic process GO:0006071 20 17 0,000 0,0723278 0,11031428 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,0723278 0,11024118 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,0723278 0,11016817 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,0723278 0,11009526 ! signal complex assembly GO:0007172 29 17 0,000 0,0723278 0,11002244 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,0723278 0,10994973 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,0723278 0,1098771 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,0723278 0,10980458 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,0723278 0,10973215 ! memory GO:0007613 25 17 0,000 0,0723278 0,10965981 ! keratinization GO:0031424 17 17 0,000 0,0723278 0,10958757 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,0723278 0,10951543 ! retinoid metabolic process GO:0001523 22 17 0,000 0,0723278 0,10944338 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,0723278 0,10937142 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,0723278 0,10929956 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,0723278 0,1092278 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,0723278 0,10915613 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,0723278 0,10908455 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,0723278 0,10901306 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,0723278 0,10894167 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,0723278 0,10887038 ! membrane budding GO:0006900 29 17 0,000 0,0723278 0,10879917 ! heme metabolic process GO:0042168 27 17 0,000 0,0723278 0,10872806 ! actin filament bundle formation GO:0051017 26 17 0,000 0,0723278 0,10865704 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,0723278 0,10858612 ! body fluid secretion GO:0007589 27 17 0,000 0,0723278 0,10851529 ! stem cell differentiation GO:0048863 36 17 0,000 0,0723278 0,10844455 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,0723278 0,1083739 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,0723278 0,10830334 ! sensory perception of pain GO:0019233 23 17 0,000 0,0723278 0,10823288 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,0723278 0,10816251 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,0723278 0,10809223 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,0723278 0,10802204 ! synaptogenesis GO:0007416 24 17 0,000 0,0723278 0,10795194 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,0723278 0,10788193 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,0723278 0,10781201 ! cell-cell junction organization GO:0045216 25 17 0,000 0,0723278 0,10774219 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,0723278 0,10767245 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,0723278 0,1076028 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,0723278 0,10753325 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,0723278 0,10746378 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,0723278 0,10739441 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,07641774 0,11339406 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,07641774 0,11332095 ! positive regulation of translation GO:0045727 28 18 0,000 0,07641774 0,11324793 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,07641774 0,11317501 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,07641774 0,11310218 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,07641774 0,11302945 ! cAMP metabolic process GO:0046058 33 18 0,000 0,07641774 0,11295681 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,07641774 0,11288426 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,07641774 0,1128118 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,07641774 0,11273944 ! axis specification GO:0009798 26 18 0,000 0,07641774 0,11266717 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,07641774 0,112595 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,07641774 0,11252291 ! pancreas development GO:0031016 26 18 0,000 0,07641774 0,11245092 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,07641774 0,11237902 ! glutamine metabolic process GO:0006541 23 18 0,000 0,07641774 0,11230722 ! pigmentation during development GO:0048066 31 18 0,000 0,07641774 0,1122355 ! central nervous system neuron development GO:0021954 30 18 0,000 0,07641774 0,11216387 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,07641774 0,11209234 ! fucose metabolic process GO:0006004 26 18 0,000 0,07641774 0,1120209 ! response to fungus GO:0009620 19 18 0,000 0,07641774 0,11194955 ! peptide cross-linking GO:0018149 31 18 0,000 0,07641774 0,11187829 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,07641774 0,11180712 ! heart process GO:0003015 27 18 0,000 0,07641774 0,11173604 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,07641774 0,11166505 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,07641774 0,11159415 ! visual learning GO:0008542 35 18 0,000 0,07641774 0,11152335 ! somitogenesis GO:0001756 24 18 0,000 0,07641774 0,11145263 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,07641774 0,111382 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,07641774 0,11131146 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,07641774 0,11124101 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,07641774 0,11117065 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,07641774 0,11110037 ! vitamin transport GO:0051180 24 18 0,000 0,07641774 0,11103019 ! hormone transport GO:0009914 27 18 0,000 0,07641774 0,1109601 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,07641774 0,11089009 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,07641774 0,11082017 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,07641774 0,11075034 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,07641774 0,1106806 ! cell-cell recognition GO:0009988 20 18 0,000 0,07641774 0,11061095 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,07641774 0,11054138 ! regulation of glucose import GO:0046324 21 18 0,000 0,07641774 0,1104719 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,07641774 0,11040251 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,07641774 0,1103332 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,07641774 0,11026398 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,08048987 0,1160669 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,08048987 0,11599418 ! positive regulation of ossification GO:0045778 30 19 0,000 0,08048987 0,11592155 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,08048987 0,11584901 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,08048987 0,11577656 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,08048987 0,11570419 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,08048987 0,11563192 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,08048987 0,11555974 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,08048987 0,11548766 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,08048987 0,11541566 ! regeneration GO:0031099 32 19 0,000 0,08048987 0,11534375 ! response to alkaloid GO:0043279 32 19 0,000 0,08048987 0,11527192 ! sensory perception of taste GO:0050909 23 19 0,000 0,08048987 0,11520019 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,08048987 0,11512855 ! smooth muscle contraction GO:0006939 36 19 0,000 0,08048987 0,115057 ! peroxisome organization GO:0007031 29 19 0,000 0,08048987 0,11498554 ! digestive system process GO:0022600 30 19 0,000 0,08048987 0,11491416 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,08048987 0,11484287 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,08048987 0,11477167 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,08048987 0,11470056 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,08048987 0,11462954 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,08048987 0,11455861 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,08048987 0,11448776 ! response to starvation GO:0042594 30 19 0,000 0,08048987 0,114417 ! sex determination GO:0007530 29 19 0,000 0,08048987 0,11434633 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,08048987 0,11427575 ! plasma membrane fusion GO:0045026 23 19 0,000 0,08048987 0,11420525 ! cytolysis GO:0019835 20 19 0,000 0,08048987 0,11413484 ! renal system process GO:0003014 35 19 0,000 0,08048987 0,11406452 ! vasodilation GO:0042311 33 19 0,000 0,08048987 0,11399428 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,08048987 0,11392413 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,08048987 0,11385407 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,08048987 0,11378409 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,08048987 0,1137142 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,08048987 0,11364439 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,08048987 0,11357467 ! sarcomere organization GO:0045214 23 19 0,000 0,08048987 0,11350503 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,08048987 0,11343548 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,08048987 0,11336602 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,08048987 0,11329664 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,08048987 0,11322735 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,08048987 0,11315814 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,08048987 0,11308901 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,08048987 0,11301997 ! protein stabilization GO:0050821 26 19 0,000 0,08048987 0,11295101 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,08454429 0,11856821 ! iron ion transport GO:0006826 37 20 0,000 0,08454429 0,11849596 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,08454429 0,11842379 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,08454429 0,11835172 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,08454429 0,11827973 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,08454429 0,11820782 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,08454429 0,11813601 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,08454429 0,11806428 ! spinal cord development GO:0021510 31 20 0,000 0,08454429 0,11799264 ! response to ethanol GO:0045471 37 20 0,000 0,08454429 0,11792109 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,08454429 0,11784962 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,08454429 0,11777824 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,08454429 0,11770694 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,08454429 0,11763574 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,08454429 0,11756461 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,08454429 0,11749358 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,08454429 0,11742263 ! pallium development GO:0021543 38 20 0,000 0,08454429 0,11735176 ! DNA modification GO:0006304 28 20 0,000 0,08454429 0,11728098 ! collagen fibril organization GO:0030199 45 20 0,000 0,08454429 0,11721029 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,08454429 0,11713968 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,08454429 0,11706916 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,08454429 0,11699872 ! collagen catabolic process GO:0030574 25 20 0,000 0,08454429 0,11692836 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,08454429 0,11685809 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,08454429 0,11678791 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,08454429 0,11671781 ! alditol metabolic process GO:0019400 24 20 0,000 0,08454429 0,11664779 ! actin filament-based movement GO:0030048 34 20 0,000 0,08454429 0,11657786 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,08858106 0,12207097 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,08858106 0,12199787 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,08858106 0,12192486 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,08858106 0,12185194 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,08858106 0,1217791 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,08858106 0,12170636 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,08858106 0,1216337 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,08858106 0,12156112 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,08858106 0,12148864 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,08858106 0,12141624 ! protein amino acid acylation GO:0043543 37 21 0,000 0,08858106 0,12134392 ! vesicle docking GO:0048278 27 21 0,000 0,08858106 0,12127169 ! phototransduction GO:0007602 25 21 0,000 0,08858106 0,12119955 ! visual behavior GO:0007632 39 21 0,000 0,08858106 0,12112749 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,08858106 0,12105552 ! ovarian follicle development GO:0001541 30 21 0,000 0,08858106 0,12098364 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,08858106 0,12091184 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,08858106 0,12084012 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,08858106 0,12076849 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,08858106 0,12069694 ! cell aging GO:0007569 32 21 0,000 0,08858106 0,12062548 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,08858106 0,12055411 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,08858106 0,12048282 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,08858106 0,12041161 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,08858106 0,12034049 ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,08858106 0,12026945 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,08858106 0,12019849 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,08858106 0,12012762 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,08858106 0,12005683 ! fatty acid transport GO:0015908 30 21 0,000 0,08858106 0,11998613 ! immunoglobulin production GO:0002377 33 21 0,000 0,08858106 0,1199155 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,08858106 0,11984497 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,08858106 0,11977451 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,08858106 0,11970414 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,08858106 0,11963385 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,08858106 0,11956364 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,08858106 0,11949351 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,08858106 0,11942347 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,08858106 0,11935351 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,08858106 0,11928363 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,08858106 0,11921383 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,08858106 0,11914412 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,08858106 0,11907448 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,08858106 0,11900493 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,08858106 0,11893546 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,09260026 0,1242594 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,09260026 0,12418694 ! viral genome replication GO:0019079 29 22 0,000 0,09260026 0,12411457 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,09260026 0,12404229 ! leukocyte adhesion GO:0007159 38 22 0,000 0,09260026 0,12397008 ! molting cycle process GO:0022404 40 22 0,000 0,09260026 0,12389797 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! glutamate signaling pathway GO:0007215 34 22 0,000 0,09260026 0,12382593 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,09260026 0,12375398 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,09260026 0,12368212 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,09260026 0,12361033 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,09260026 0,12353863 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,09260026 0,12346702 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,09260026 0,12339548 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,09260026 0,12332403 ! lysosome organization GO:0007040 37 22 0,000 0,09260026 0,12325266 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,09260026 0,12318138 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,09260026 0,12311018 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,09260026 0,12303905 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,09260026 0,12296802 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,09260026 0,12289706 ! membrane depolarization GO:0051899 35 22 0,000 0,09260026 0,12282618 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,09260026 0,12275539 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,09260026 0,12268468 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,09260026 0,12261405 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,09260026 0,1225435 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,09260026 0,12247303 ! blastocyst development GO:0001824 37 22 0,000 0,09260026 0,12240265 ! neural tube closure GO:0001843 33 22 0,000 0,09260026 0,12233234 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,09260026 0,12226211 ! protein tetramerization GO:0051262 39 22 0,000 0,09260026 0,12219197 ! neuron fate commitment GO:0048663 32 23 0,000 0,09660197 0,12739938 ! embryonic pattern specification GO:0009880 31 23 0,000 0,09660197 0,12732638 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,09660197 0,12725345 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,09660197 0,12718061 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,09660197 0,12710785 ! vesicle targeting GO:0006903 32 23 0,000 0,09660197 0,12703518 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,09660197 0,12696259 ! osteoblast differentiation GO:0001649 40 23 0,000 0,09660197 0,12689008 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,09660197 0,12681765 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,09660197 0,12674531 ! interaction with host GO:0051701 37 23 0,000 0,09660197 0,12667305 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,09660197 0,12660087 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,09660197 0,12652877 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,09660197 0,12645676 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,09660197 0,12638483 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,09660197 0,12631298 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,09660197 0,12624121 ! cell fate determination GO:0001709 45 23 0,000 0,09660197 0,12616952 ! pentose metabolic process GO:0019321 31 23 0,000 0,09660197 0,12609792 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,09660197 0,12602639 ! spermatid development GO:0007286 33 23 0,000 0,09660197 0,12595495 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,09660197 0,12588358 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,09660197 0,1258123 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,09660197 0,1257411 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,09660197 0,12566998 ! telomere organization GO:0032200 32 23 0,000 0,09660197 0,12559894 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,09660197 0,12552798 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,09660197 0,1254571 ! regulation of amine transport GO:0051952 38 23 0,000 0,09660197 0,1253863 ! liver development GO:0001889 40 23 0,000 0,09660197 0,12531558 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,10058625 0,13041059 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,10058625 0,13033712 ! initiation of viral infection GO:0019059 42 24 0,000 0,10058625 0,13026373 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,10058625 0,13019042 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,10058625 0,1301172 ! superoxide metabolic process GO:0006801 32 24 0,000 0,10058625 0,13004406 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,10058625 0,129971 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,10058625 0,12989803 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,10058625 0,12982513 ! sperm motility GO:0030317 27 24 0,000 0,10058625 0,12975232 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,10058625 0,12967959 ! vacuole organization GO:0007033 39 24 0,000 0,10058625 0,12960694 ! receptor metabolic process GO:0043112 37 24 0,000 0,10058625 0,12953437 ! neural crest cell development GO:0014032 39 24 0,000 0,10058625 0,12946188 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,10058625 0,12938948 ! primary neural tube formation GO:0014020 35 24 0,000 0,10058625 0,12931715 ! negative regulation of cell development GO:0010721 56 24 0,000 0,10058625 0,12924491 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,10058625 0,12917274 ! base-excision repair GO:0006284 31 24 0,000 0,10058625 0,12910066 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,10058625 0,12902866 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glutathione metabolic process GO:0006749 29 24 0,000 0,10058625 0,12895674 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,10058625 0,12888489 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,10058625 0,12881313 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,10058625 0,12874145 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,1045532 0,13374435 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,1045532 0,13367001 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,1045532 0,13359575 ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,1045532 0,13352157 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,1045532 0,13344747 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,1045532 0,13337346 ! peptide transport GO:0015833 43 25 0,000 0,1045532 0,13329953 ! iron ion homeostasis GO:0055072 39 25 0,000 0,1045532 0,13322568 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,1045532 0,13315191 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,1045532 0,13307822 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,1045532 0,13300462 ! phospholipid transport GO:0015914 35 25 0,000 0,1045532 0,13293109 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,1045532 0,13285765 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,1045532 0,13278429 ! detection of light stimulus GO:0009583 30 25 0,000 0,1045532 0,13271101 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,1045532 0,13263781 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,1045532 0,13256469 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,10850287 0,13749674 ! translational initiation GO:0006413 43 26 0,000 0,10850287 0,13742103 ! regulation of pH GO:0006885 36 26 0,000 0,10850287 0,1373454 ! circadian rhythm GO:0007623 42 26 0,000 0,10850287 0,13726985 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,10850287 0,13719439 ! post-embryonic development GO:0009791 42 26 0,000 0,10850287 0,13711901 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,10850287 0,13704371 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,10850287 0,13696849 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,10850287 0,13689336 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,10850287 0,13681831 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,10850287 0,13674334 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,10850287 0,13666845 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,10850287 0,13659365 ! regulation of coagulation GO:0050818 39 26 0,000 0,10850287 0,13651892 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,11243534 0,14138944 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,11243534 0,14131218 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,11243534 0,141235 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,11243534 0,14115791 ! membrane docking GO:0022406 39 27 0,000 0,11243534 0,1410809 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,11243534 0,14100397 ! catechol metabolic process GO:0009712 43 27 0,000 0,11243534 0,14092713 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,11243534 0,14085037 ! acute-phase response GO:0006953 42 27 0,000 0,11243534 0,1407737 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,11243534 0,14069711 ! myofibril assembly GO:0030239 36 27 0,000 0,11243534 0,1406206 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,11243534 0,14054418 ! response to ionizing radiation GO:0010212 47 27 0,000 0,11243534 0,14046783 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,11243534 0,14039158 ! natural killer cell activation GO:0030101 35 27 0,000 0,11243534 0,1403154 ! lipid oxidation GO:0034440 38 27 0,000 0,11243534 0,14023931 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,11243534 0,1401633 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,11243534 0,14008737 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,11243534 0,14001152 ! negative regulation of protein transport GO:0051224 49 27 0,000 0,11243534 0,13993576 ! gene silencing GO:0016458 41 27 0,000 0,11243534 0,13986008 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,11635069 0,14465221 ! phenol metabolic process GO:0018958 44 28 0,000 0,11635069 0,14457407 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,11635069 0,144496 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,11635069 0,14441802 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,11635069 0,14434013 ! cell junction assembly GO:0034329 56 28 0,000 0,11635069 0,14426232 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,11635069 0,14418459 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,11635069 0,14410694 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,11635069 0,14402938 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,11635069 0,14395191 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,11635069 0,14387451 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,11635069 0,1437972 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,11635069 0,14371998 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,11635069 0,14364283 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,11635069 0,14356577 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,11635069 0,14348879 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,11635069 0,14341189 ! mesoderm formation GO:0001707 46 28 0,000 0,11635069 0,14333508 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,11635069 0,14325835 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,11635069 0,1431817 ! BMP signaling pathway GO:0030509 40 28 0,000 0,11635069 0,14310513 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,11635069 0,14302864 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,11635069 0,14295224 ! neural tube formation GO:0001841 41 28 0,000 0,11635069 0,14287592 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,11635069 0,14279968 ! placenta development GO:0001890 37 28 0,000 0,11635069 0,14272352 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,120249 0,14742681 ! regulation of innate immune response GO:0045088 38 29 0,000 0,120249 0,14734827 ! ovulation cycle process GO:0022602 41 29 0,000 0,120249 0,1472698 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,120249 0,14719143 ! protein targeting to membrane GO:0006612 53 29 0,000 0,120249 0,14711313 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,120249 0,14703492 ! mismatch repair GO:0006298 34 29 0,000 0,120249 0,1469568 ! muscle cell development GO:0055001 38 29 0,000 0,120249 0,14687875 ! formation of primary germ layer GO:0001704 48 29 0,000 0,120249 0,14680079 ! telencephalon development GO:0021537 52 29 0,000 0,120249 0,14672291 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,120249 0,14664512 ! eye morphogenesis GO:0048592 51 29 0,000 0,120249 0,14656741 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,120249 0,14648977 ! tissue homeostasis GO:0001894 42 29 0,000 0,120249 0,14641223 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,12413033 0,15105807 ! collagen metabolic process GO:0032963 40 30 0,000 0,12413033 0,15097819 ! organic anion transport GO:0015711 51 30 0,000 0,12413033 0,15089839 ! cholesterol transport GO:0030301 46 30 0,000 0,12413033 0,15081867 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,12413033 0,15073904 ! spindle organization GO:0007051 37 30 0,000 0,12413033 0,1506595 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,12413033 0,15058004 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,12413033 0,15050066 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,12413033 0,15042136 ! ceramide metabolic process GO:0006672 43 30 0,000 0,12413033 0,15034215 ! ovulation cycle GO:0042698 43 30 0,000 0,12413033 0,15026303 ! hindbrain development GO:0030902 45 30 0,000 0,12413033 0,15018398 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,12413033 0,15010502 ! adult locomotory behavior GO:0008344 47 30 0,000 0,12413033 0,15002614 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,12413033 0,14994735 ! response to heat GO:0009408 41 30 0,000 0,12413033 0,14986863 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,12413033 0,14979 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,12413033 0,14971146 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,12799475 0,15429137 ! negative regulation of secretion GO:0051048 49 31 0,000 0,12799475 0,15421054 ! glial cell differentiation GO:0010001 55 31 0,000 0,12799475 0,15412981 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,12799475 0,15404915 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,12799475 0,15396858 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,12799475 0,1538881 ! odontogenesis GO:0042476 50 31 0,000 0,12799475 0,1538077 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,12799475 0,15372738 ! segmentation GO:0035282 41 31 0,000 0,12799475 0,15364714 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,12799475 0,15356699 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,12799475 0,15348693 ! metanephros development GO:0001656 58 31 0,000 0,12799475 0,15340695 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,12799475 0,15332705 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,12799475 0,15324723 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,12799475 0,1531675 ! cell fate specification GO:0001708 37 31 0,000 0,12799475 0,15308785 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,12799475 0,15300828 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,12799475 0,15292879 ! RNA modification GO:0009451 40 31 0,000 0,12799475 0,15284939 ! regulation of muscle development GO:0048634 48 32 0,000 0,13184235 0,15736243 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,13184235 0,15728081 ! meiosis I GO:0007127 52 32 0,000 0,13184235 0,15719927 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,13184235 0,15711782 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,13184235 0,15703646 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,13184235 0,15695518 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,13184235 0,15687398 ! regulation of protein stability GO:0031647 48 32 0,000 0,13184235 0,15679286 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,13184235 0,15671184 ! cytokine production GO:0001816 44 32 0,000 0,13184235 0,15663089 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,13184235 0,15655003 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,13184235 0,15646925 ! vesicle localization GO:0051648 47 32 0,000 0,13184235 0,15638855 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,13567319 0,16084965 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,13567319 0,16076679 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,13567319 0,160684 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,13567319 0,1606013 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,13567319 0,16051869 ! ear morphogenesis GO:0042471 42 33 0,000 0,13567319 0,16043616 ! actomyosin structure organization GO:0031032 43 33 0,000 0,13567319 0,16035372 ! cell junction organization GO:0034330 63 33 0,000 0,13567319 0,16027136 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,13567319 0,16018908 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,13567319 0,16010689 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,13567319 0,16002478 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,13567319 0,15994276 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,13567319 0,15986082 ! female gonad development GO:0008585 49 33 0,000 0,13567319 0,15977897 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,13567319 0,1596972 ! positive regulation of cell development GO:0010720 54 33 0,000 0,13567319 0,15961551 ! lipid homeostasis GO:0055088 55 33 0,000 0,13567319 0,15953391 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,13567319 0,15945239 ! regulation of proteolysis GO:0030162 50 33 0,000 0,13567319 0,15937096 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,13567319 0,1592896 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,13567319 0,15920833 ! cytokinesis GO:0000910 52 33 0,000 0,13567319 0,15912714 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,13567319 0,15904604 ! mRNA catabolic process GO:0006402 48 34 0,000 0,13948734 0,16343397 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,13948734 0,16335076 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,13948734 0,16326763 ! feeding behavior GO:0007631 45 34 0,000 0,13948734 0,16318458 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,13948734 0,16310162 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,13948734 0,16301874 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,13948734 0,16293595 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,13948734 0,16285324 ! neuron migration GO:0001764 46 34 0,000 0,13948734 0,16277062 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,13948734 0,16268807 ! female gamete generation GO:0007292 43 34 0,000 0,13948734 0,16260562 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,13948734 0,16252324 ! polyol metabolic process GO:0019751 44 34 0,000 0,13948734 0,16244095 ! aerobic respiration GO:0009060 47 34 0,000 0,13948734 0,16235875 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,13948734 0,16227662 ! embryonic organ development GO:0048568 45 34 0,000 0,13948734 0,16219458 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,13948734 0,16211262 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,14328488 0,16644203 ! Notch signaling pathway GO:0007219 56 35 0,000 0,14328488 0,16635801 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,14328488 0,16627408 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,14328488 0,16619023 GO:0032313|regulation of Rab GTPase activity, ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,14328488 0,16610646 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,14328488 0,16602278 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,14328488 0,16593919 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,14328488 0,16585567 ! pigment metabolic process GO:0042440 61 35 0,000 0,14328488 0,16577225 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,14706588 0,1700611 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,14706588 0,16997564 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,14706588 0,16989027 ! negative regulation of binding GO:0051100 58 36 0,000 0,14706588 0,16980498 ! organic ether metabolic process GO:0018904 46 36 0,000 0,14706588 0,16971978 ! neural tube development GO:0021915 50 36 0,000 0,14706588 0,16963466 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,14706588 0,16954963 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,14706588 0,16946469 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,14706588 0,16937983 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,14706588 0,16929505 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,1508304 0,17354174 GO:0006956|complement activation, ! learning GO:0007612 67 37 0,000 0,1508304 0,17345497 ! ion transmembrane transport GO:0034220 56 37 0,000 0,1508304 0,17336828 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,1508304 0,17328168 ! regulation of protein secretion GO:0050708 51 37 0,000 0,1508304 0,17319517 ! amino acid activation GO:0043038 52 37 0,000 0,1508304 0,17310875 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,1508304 0,17302241 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,15457853 0,17723361 ! gliogenesis GO:0042063 71 38 0,000 0,15457853 0,1771453 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,15457853 0,17705708 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,15457853 0,17696895 ! phagocytosis GO:0006909 60 38 0,000 0,15457853 0,17688091 ! mesenchymal cell development GO:0014031 64 38 0,000 0,15457853 0,17679295 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,15457853 0,17670508 ! maintenance of location in cell GO:0051651 69 38 0,000 0,15457853 0,1766173 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,15831033 0,18079134 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,15831033 0,18070161 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,15831033 0,18061198 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,15831033 0,18052243 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,15831033 0,18043298 ! chromatin remodeling GO:0006338 68 39 0,000 0,15831033 0,18034361 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,15831033 0,18025433 ! JNK cascade GO:0007254 54 39 0,000 0,15831033 0,18016514 ! developmental growth GO:0048589 62 39 0,000 0,15831033 0,18007604 ! cell growth GO:0016049 61 39 0,000 0,15831033 0,17998702 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,16202586 0,1841203 ! response to calcium ion GO:0051592 58 40 0,000 0,16202586 0,18402938 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,16202586 0,18393854 ! regulation of tube size GO:0035150 60 40 0,000 0,16202586 0,1838478 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,16202586 0,18375714 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,16202586 0,18366658 ! inner ear development GO:0048839 57 40 0,000 0,16202586 0,1835761 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,16202586 0,18348571 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,16202586 0,18339542 ! double-strand break repair GO:0006302 67 40 0,000 0,16202586 0,18330521 ! B cell differentiation GO:0030183 62 40 0,000 0,16202586 0,18321509 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,16202586 0,18312505 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,16572521 0,18721414 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,16572521 0,18712223 ! glucose transport GO:0015758 52 41 0,000 0,16572521 0,18703041 ! endosome transport GO:0016197 71 41 0,000 0,16572521 0,18693869 ! striated muscle contraction GO:0006941 62 41 0,000 0,16572521 0,18684705 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,16572521 0,1867555 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,16572521 0,18666405 ! mitochondrial transport GO:0006839 60 42 0,000 0,16940844 0,19071924 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,16940844 0,19062593 ! cellular component disassembly GO:0022411 64 42 0,000 0,16940844 0,19053272 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,16940844 0,19043959 ! hexose transport GO:0008645 54 42 0,000 0,16940844 0,19034656 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,16940844 0,19025362 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,16940844 0,19016076 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,16940844 0,190068 ! excretion GO:0007588 63 42 0,000 0,16940844 0,18997533 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,16940844 0,18988275 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,16940844 0,18979026 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,16940844 0,18969786 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,17307561 0,19370993 ! leukocyte migration GO:0050900 60 43 0,000 0,17307561 0,19361571 ! neuromuscular process GO:0050905 79 43 0,000 0,17307561 0,19352159 ! activation of caspase activity GO:0006919 65 43 0,000 0,17307561 0,19342756 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,17307561 0,19333361 ! tRNA processing GO:0008033 49 43 0,000 0,17307561 0,19323976 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,17307561 0,193146 ! vesicle organization GO:0016050 79 43 0,000 0,17307561 0,19305233 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,17307561 0,19295875 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,17672681 0,19693394 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,17672681 0,19683857 ! glycolysis GO:0006096 53 44 0,000 0,17672681 0,1967433 ! regulation of ion transport GO:0043269 57 44 0,000 0,17672681 0,19664812 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,17672681 0,19655303 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,17672681 0,19645803 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,17672681 0,19636312 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,17672681 0,1962683 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,17672681 0,19617358 ! RNA catabolic process GO:0006401 64 45 0,000 0,18036209 0,2001123 ! positive regulation of defense response GO:0031349 59 45 0,000 0,18036209 0,20001582 ! regulation of translational initiation GO:0006446 64 45 0,000 0,18036209 0,19991942 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,18036209 0,19982312 ! cell recognition GO:0008037 58 45 0,000 0,18036209 0,19972692 ! cell maturation GO:0048469 60 45 0,000 0,18036209 0,1996308 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,18398153 0,20353897 ! cell redox homeostasis GO:0045454 63 46 0,000 0,18398153 0,20344111 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,18398153 0,20334335 ! regulation of ossification GO:0030278 71 46 0,000 0,18398153 0,20324568 ! histone modification GO:0016570 68 46 0,000 0,18398153 0,20314811 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,18398153 0,20305063 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,18758519 0,2069285 ! viral infectious cycle GO:0019058 71 47 0,000 0,18758519 0,2068293 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,18758519 0,2067302 ! endocrine system development GO:0035270 83 47 0,000 0,18758519 0,20663119 ! covalent chromatin modification GO:0016569 75 47 0,000 0,18758519 0,20653228 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,18758519 0,20643346 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,18758519 0,20633473 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,18758519 0,2062361 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,18758519 0,20613757 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,18758519 0,20603912 ! chloride transport GO:0006821 67 48 0,000 0,19117314 0,20987982 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,19117314 0,20977968 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 0,000 0,19117314 0,20967965 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,19117314 0,2095797 ! gastrulation GO:0007369 73 48 0,000 0,19117314 0,20947986 ! regulation of DNA replication GO:0006275 75 48 0,000 0,19117314 0,2093801 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,19117314 0,20928045 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,19117314 0,20918088 ! regulation of endocytosis GO:0030100 63 48 0,000 0,19117314 0,20908142 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,19117314 0,20898204 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,19474545 0,212786 ! sensory perception of smell GO:0007608 61 49 0,000 0,19474545 0,21268496 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,19474545 0,21258402 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,19474545 0,21248317 ! RNA elongation GO:0006354 62 49 0,000 0,19474545 0,21238242 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,19474545 0,21228177 ! germ cell development GO:0007281 68 49 0,000 0,19474545 0,21218121 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,19474545 0,21208074 ! maintenance of location GO:0051235 84 49 0,000 0,19474545 0,21198037 ! regulation of actin filament length GO:0030832 72 50 0,000 0,19830219 0,21574978 ! ear development GO:0043583 72 50 0,000 0,19830219 0,21564777 ! membrane fusion GO:0006944 80 50 0,000 0,19830219 0,21554585 ! proton transport GO:0015992 75 50 0,000 0,19830219 0,21544404 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,19830219 0,21534232 ! positive regulation of secretion GO:0051047 71 51 0,000 0,20184342 0,21908441 ! hydrogen transport GO:0006818 77 51 0,000 0,20184342 0,21898107 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,20184342 0,21887782 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,20184342 0,21877467 ! adult behavior GO:0030534 80 51 0,000 0,20184342 0,21867162 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,20184342 0,21856867 ! transition metal ion transport GO:0000041 74 52 0,000 0,20536921 0,22228197 ! regulation of cellular component size GO:0032535 74 52 0,000 0,20536921 0,22217741 ! aging GO:0007568 79 52 0,000 0,20536921 0,22207296 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,20536921 0,2219686 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,20536921 0,22186434 ! establishment of organelle localization GO:0051656 85 52 0,000 0,20536921 0,22176018 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,20887962 0,22544493 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,20887962 0,22533918 ! kidney development GO:0001822 90 53 0,000 0,20887962 0,22523354 ! single fertilization GO:0007338 59 53 0,000 0,20887962 0,22512799 ! cell projection assembly GO:0030031 76 53 0,000 0,20887962 0,22502255 ! amino acid transport GO:0006865 84 54 0,000 0,21237473 0,22868066 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,21237473 0,22857365 ! regulation of mitosis GO:0007088 84 54 0,000 0,21237473 0,22846674 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,21237473 0,22835993 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,21237473 0,22825322 ! DNA catabolic process GO:0006308 67 54 0,000 0,21237473 0,22814661 ! detection of external stimulus GO:0009581 66 54 0,000 0,21237473 0,2280401 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,21237473 0,22793369 ! exocytosis GO:0006887 74 55 0,000 0,2158546 0,23156044 ! mesoderm development GO:0007498 76 55 0,000 0,2158546 0,23145249 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,2158546 0,23134463 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,2158546 0,23123688 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,21931929 0,2348391 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,21931929 0,23472982 ! carbohydrate transport GO:0008643 74 57 0,000 0,22276888 0,23831089 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,22276888 0,2382001 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,22276888 0,23808941 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,22276888 0,23797883 ! camera-type eye development GO:0043010 88 57 0,000 0,22276888 0,23786835 ! secondary metabolic process GO:0019748 84 57 0,000 0,22276888 0,23775797 ! developmental maturation GO:0021700 75 57 0,000 0,22276888 0,23764769 ! viral reproductive process GO:0022415 87 58 0,000 0,22620341 0,24119975 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,22620341 0,24108798 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,22620341 0,24097631 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,22962297 0,24450594 ! actin filament organization GO:0007015 95 59 0,000 0,22962297 0,24439279 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,22962297 0,24427975 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,23302761 0,2477871 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,23302761 0,2476726 GO:0035113|embryonic appendage morphogenesis, ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,23302761 0,2475582 ! regulation of heart contraction GO:0008016 91 60 0,000 0,23302761 0,24744391 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,23302761 0,24732972 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,2364174 0,25081181 ! meiosis GO:0007126 96 61 0,000 0,2364174 0,25069618 GO:0051327|M phase of meiotic cell cycle, ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,2364174 0,25058065 ! urogenital system development GO:0001655 101 61 0,000 0,2364174 0,25046523 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,2364174 0,25034991 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,2364174 0,2502347 ! extracellular matrix organization GO:0030198 103 61 0,000 0,2364174 0,2501196 ! amine catabolic process GO:0009310 90 62 0,000 0,23979239 0,25357357 ! neurotransmitter transport GO:0006836 81 62 0,000 0,23979239 0,25345703 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,23979239 0,25334061 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,23979239 0,25322429 ! meiotic cell cycle GO:0051321 97 62 0,000 0,23979239 0,25310808 ! organelle localization GO:0051640 96 62 0,000 0,23979239 0,25299198 ! regulation of transcription factor activity GO:0051090 97 63 0,000 0,24315267 0,2564196 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,24315267 0,25630208 ! viral reproduction GO:0016032 92 63 0,000 0,24315267 0,25618467 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,24649828 0,25959068 ! appendage morphogenesis GO:0035107 93 64 0,000 0,24649828 0,25947188 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,24649828 0,25935318 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,24649828 0,25923459 ! hexose catabolic process GO:0019320 82 64 0,000 0,24649828 0,25911611 ! appendage development GO:0048736 94 65 0,000 0,2498293 0,26249766 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,2498293 0,2623778 ! defense response to bacterium GO:0042742 73 65 0,000 0,2498293 0,26225805 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,2498293 0,26213841 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,2498293 0,26201887 ! activation of immune response GO:0002253 83 65 0,000 0,2498293 0,26189945 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,25314578 0,26525526 ! antigen processing and presentation GO:0019882 96 66 0,000 0,25314578 0,26513447 ! regulation of immune effector process GO:0002697 101 66 0,000 0,25314578 0,26501379 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,25644779 0,26834846 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,25644779 0,26822643 ! acute inflammatory response GO:0002526 92 68 0,000 0,25973539 0,27154154 ! learning or memory GO:0007611 123 68 0,000 0,25973539 0,27141817 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,25973539 0,27129491 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,25973539 0,27117176 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,25973539 0,27104872 ! rhythmic process GO:0048511 105 68 0,000 0,25973539 0,2709258 ! inorganic anion transport GO:0015698 93 68 0,000 0,25973539 0,27080299 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,26300864 0,27409146 ! response to drug GO:0042493 108 69 0,000 0,26300864 0,27396733 ! response to metal ion GO:0010038 103 70 0,000 0,2662676 0,27723652 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,2662676 0,27711108 ! humoral immune response GO:0006959 86 70 0,000 0,2662676 0,27698574 ! eye development GO:0001654 111 70 0,000 0,2662676 0,27686052 ! amine transport GO:0015837 101 70 0,000 0,2662676 0,27673542 ! regulation of catabolic process GO:0009894 106 70 0,000 0,2662676 0,27661042 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,26951234 0,2798548 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,26951234 0,27972851 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,26951234 0,27960234 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,26951234 0,27947628 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,27274291 0,28269883 ! negative regulation of transport GO:0051051 116 73 0,000 0,27595939 0,28590387 ! regulation of blood pressure GO:0008217 107 73 0,000 0,27595939 0,28577514 ! tube morphogenesis GO:0035239 118 73 0,000 0,27595939 0,28564653 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,27595939 0,28551803 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,27595939 0,28538965 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,27916182 0,28857177 ! digestion GO:0007586 97 74 0,000 0,27916182 0,28844213 ! protein import into nucleus GO:0006606 118 74 0,000 0,27916182 0,28831261 ! blood coagulation GO:0007596 116 75 0,000 0,28235027 0,29147469 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,28235027 0,29134393 ! nuclear import GO:0051170 121 75 0,000 0,28235027 0,29121328 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,28235027 0,29108275 ! tRNA metabolic process GO:0006399 95 76 0,000 0,2855248 0,29422358 ! response to unfolded protein GO:0006986 99 76 0,000 0,2855248 0,29409182 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,28868547 0,29721422 ! protein ubiquitination GO:0016567 125 77 0,000 0,28868547 0,29708124 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,28868547 0,29694838 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,28868547 0,29681563 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,29183233 0,29991705 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,29183233 0,2997831 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,29496546 0,30286632 ! cellular respiration GO:0045333 107 79 0,000 0,29496546 0,30273117 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,29496546 0,30259614 ! T cell activation GO:0042110 134 79 0,000 0,29496546 0,30246124 ! regulation of lyase activity GO:0051339 133 79 0,000 0,29496546 0,30232645 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,29496546 0,30219178 ! chromatin assembly GO:0031497 102 80 0,000 0,2980849 0,30525168 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,2980849 0,30511583 ! protein localization in nucleus GO:0034504 133 80 0,000 0,2980849 0,3049801 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,2980849 0,3048445 ! forebrain development GO:0030900 131 80 0,000 0,2980849 0,30470901 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,30119072 0,30774707 ! hemostasis GO:0007599 125 81 0,000 0,30119072 0,30761042 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,30119072 0,30747388 ! response to protein stimulus GO:0051789 111 81 0,000 0,30119072 0,30733747 ! regulation of neurological system process GO:0031644 122 81 0,000 0,30119072 0,30720118 ! detection of stimulus GO:0051606 108 82 0,000 0,30428297 0,31021757 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,30736172 0,31321753 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,30736172 0,31307881 ! regulation of defense response GO:0031347 117 84 0,000 0,31042702 0,31606115 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,31042702 0,3159213 ! regulation of DNA metabolic process GO:0051052 135 85 0,000 0,31347893 0,31888613 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,31347893 0,31874515 ! rRNA metabolic process GO:0016072 107 85 0,000 0,31347893 0,3186043 GO:0006364|rRNA processing, ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,31651751 0,32155047 ! nucleosome organization GO:0034728 114 87 0,000 0,31954281 0,32448056 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,31954281 0,32433736 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,31954281 0,32419429 ! female pregnancy GO:0007565 130 87 0,000 0,31954281 0,32405135 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,32255489 0,32696177 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,32255489 0,32681773 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,32255489 0,32667382 GO:0016054|organic acid catabolic process, ! protein processing GO:0016485 114 88 0,000 0,32255489 0,32653004 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,32555382 0,32942093 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,32555382 0,32927607 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,32555382 0,32913133 ! leukocyte differentiation GO:0002521 143 90 0,000 0,32853964 0,33200403 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,32853964 0,33185822 ! hormone metabolic process GO:0042445 121 90 0,000 0,32853964 0,33171254 ! ATP metabolic process GO:0046034 137 91 0,000 0,33151241 0,33456715 ! response to virus GO:0009615 122 91 0,000 0,33151241 0,33442041 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,33447219 0,33725823 ! cell fate commitment GO:0045165 141 92 0,000 0,33447219 0,33711044 ! positive regulation of immune response GO:0050778 121 92 0,000 0,33447219 0,33696278 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,33741903 0,33978274 ! electron transport chain GO:0022900 123 94 0,000 0,340353 0,34258726 ! response to oxidative stress GO:0006979 141 94 0,000 0,340353 0,3424374 ! carboxylic acid transport GO:0046942 147 95 0,000 0,34327414 0,34522542 GO:0015849|organic acid transport, ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,34618252 0,34799816 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,34618252 0,34784613 ! protein maturation GO:0051604 129 96 0,000 0,34618252 0,34769423 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,34907818 0,3504495 ! calcium ion transport GO:0006816 167 99 0,000 0,35483157 0,35607008 ! protein import GO:0017038 156 99 0,000 0,35483157 0,35591479 ! regulation of translation GO:0006417 151 100 0,000 0,35768942 0,35862497 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,35768942 0,3584687 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,35768942 0,35831257 ! divalent metal ion transport GO:0070838 171 100 0,000 0,35768942 0,35815658 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,35768942 0,35800073 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,35768942 0,35784501 ! protein localization in organelle GO:0033365 161 100 0,000 0,35768942 0,35768942