pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6505-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! release of cytochrome c from mitochondria GO:0001836 9 8 2,000 2,65E-06 4,884E-03 ! apoptotic mitochondrial changes GO:0008637 11 10 2,000 5,651E-06 5,207E-03 ! cellular response to starvation GO:0009267 11 11 2,000 7,75E-06 4,761E-03 ! negative regulation of protein kinase activity GO:0006469 37 37 3,000 9,727E-06 4,482E-03 ! negative regulation of kinase activity GO:0033673 38 38 3,000 1,084E-05 3,997E-03 ! negative regulation of transferase activity GO:0051348 40 40 3,000 1,336E-05 4,103E-03 ! protein tetramerization GO:0051262 13 13 2,000 1,337E-05 3,519E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 3,000 1,627E-05 3,749E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 3,000 1,964E-05 4,021E-03 ! response to starvation GO:0042594 15 15 2,000 2,116E-05 3,899E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 3,000 2,15E-05 3,602E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 3,000 2,349E-05 3,607E-03 ! positive regulation of ligase activity GO:0051351 47 46 3,000 2,349E-05 3,329E-03 ! cellular response to nutrient levels GO:0031669 16 16 2,000 2,598E-05 3,419E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 3,000 2,786E-05 3,423E-03 ! regulation of ligase activity GO:0051340 50 49 3,000 3,026E-05 3,485E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 2,000 3,766E-05 4,083E-03 ! cellular response to extracellular stimulus GO:0031668 18 18 2,000 3,766E-05 3,856E-03 ! cholesterol metabolic process GO:0008203 52 52 3,000 3,837E-05 3,722E-03 ! reproductive developmental process GO:0003006 56 56 3,000 5,152E-05 4,748E-03 ! negative regulation of hydrolase activity GO:0051346 21 21 2,000 6,092E-05 5,347E-03 ! sterol metabolic process GO:0016125 59 59 3,000 6,335E-05 5,307E-03 ! proteasomal protein catabolic process GO:0010498 62 61 3,000 7,227E-05 5,791E-03 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! positive regulation of growth GO:0045927 23 23 2,000 8,072E-05 6,198E-03 ! androgen receptor signaling pathway GO:0030521 24 24 2,000 9,202E-05 6,783E-03 ! regulation of gene-specific transcription GO:0032583 25 25 2,000 1,043E-04 7,393E-03 ! regulation of cell size GO:0008361 68 68 3,000 1,108E-04 7,561E-03 ! response to nutrient levels GO:0031667 69 69 3,000 1,173E-04 7,72E-03 ! induction of apoptosis by intracellular signals GO:0008629 26 26 2,000 1,176E-04 7,474E-03 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 1,364E-04 8,379E-03 ! prostate gland development GO:0030850 5 5 1,000 1,364E-04 8,108E-03 ! ovulation GO:0030728 5 5 1,000 1,364E-04 7,855E-03 ! indolalkylamine metabolic process GO:0006586 5 5 1,000 1,364E-04 7,617E-03 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! protein heterooligomerization GO:0051291 5 5 1,000 1,364E-04 7,393E-03 ! T cell lineage commitment GO:0002360 5 5 1,000 1,364E-04 7,182E-03 ! peptidyl-lysine modification GO:0018205 5 5 1,000 1,364E-04 6,982E-03 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 1,364E-04 6,793E-03 ! response to extracellular stimulus GO:0009991 72 72 3,000 1,385E-04 6,718E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 2,000 1,474E-04 6,968E-03 ! B cell activation GO:0042113 31 31 2,000 2,008E-04 9,252E-03 ! regulation of DNA replication GO:0006275 32 31 2,000 2,008E-04 9,026E-03 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 2,041E-04 8,956E-03 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 2,041E-04 8,748E-03 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 1,000 2,041E-04 8,549E-03 ! positive regulation of cell growth GO:0030307 6 6 1,000 2,041E-04 8,359E-03 ! ER overload response GO:0006983 6 6 1,000 2,041E-04 8,177E-03 ! lipid digestion GO:0044241 6 6 1,000 2,041E-04 8,003E-03 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 2,041E-04 7,837E-03 ! intestinal absorption GO:0050892 6 6 1,000 2,041E-04 7,677E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 2,041E-04 7,523E-03 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 2,041E-04 7,376E-03 ! response to peptide hormone stimulus GO:0043434 36 34 2,000 2,653E-04 9,403E-03 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 2,851E-04 9,913E-03 ! keratinocyte proliferation GO:0043616 7 7 1,000 2,851E-04 9,73E-03 ! axis specification GO:0009798 7 7 1,000 2,851E-04 9,553E-03 ! response to X-ray GO:0010165 7 7 1,000 2,851E-04 9,382E-03 ! regulation of intracellular pH GO:0051453 7 7 1,000 2,851E-04 9,218E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 2,851E-04 9,059E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! response to gamma radiation GO:0010332 8 7 1,000 2,851E-04 8,905E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 2,895E-04 8,891E-03 ! response to drug GO:0042493 37 37 2,000 3,419E-04 0,0103303 ! DNA damage response, signal transduction GO:0042770 37 37 2,000 3,419E-04 0,01016368 ! steroid hormone receptor signaling pathway GO:0030518 38 38 2,000 3,703E-04 0,0108325 ! lipid localization GO:0010876 8 8 1,000 3,792E-04 0,01092036 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 1,000 3,792E-04 0,01075236 ! sex determination GO:0007530 8 8 1,000 3,792E-04 0,01058944 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 3,792E-04 0,01043139 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 3,792E-04 0,01027799 ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 3,792E-04 0,01012903 ! activation of MAPK activity GO:0000187 39 39 2,000 4,001E-04 0,01053525 ! nucleotide-excision repair GO:0006289 40 39 2,000 4,001E-04 0,01038687 ! protein oligomerization GO:0051259 39 39 2,000 4,001E-04 0,0102426 ! regulation of cell growth GO:0001558 97 96 3,000 4,206E-04 0,01061746 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 2,000 4,315E-04 0,01074684 ! regulation of caspase activity GO:0043281 41 41 2,000 4,644E-04 0,01141203 ! positive regulation of cell size GO:0045793 9 9 1,000 4,864E-04 0,01179608 ! negative regulation of caspase activity GO:0043154 9 9 1,000 4,864E-04 0,01164288 ! negative regulation of protein import into nucleus GO:0042308 9 9 1,000 4,864E-04 0,01149361 ! regulation of cellular pH GO:0030641 9 9 1,000 4,864E-04 0,01134812 ! histone acetylation GO:0016573 9 9 1,000 4,864E-04 0,01120627 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 3,000 4,913E-04 0,01117968 ! regulation of endopeptidase activity GO:0052548 42 42 2,000 4,989E-04 0,01121261 ! negative regulation of ligase activity GO:0051352 43 42 2,000 4,989E-04 0,01107751 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! reproductive structure development GO:0048608 43 43 2,000 5,35E-04 0,01173711 ! mitochondrion organization GO:0007005 44 43 2,000 5,35E-04 0,01159903 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 6,066E-04 0,01300027 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 6,066E-04 0,01285085 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 6,066E-04 0,01270481 ! regulation of DNA binding GO:0051101 47 45 2,000 6,12E-04 0,01267377 ! regulation of peptidase activity GO:0052547 46 46 2,000 6,531E-04 0,01337379 ! sex differentiation GO:0007548 47 47 2,000 6,959E-04 0,0140933 ! rhythmic process GO:0048511 47 47 2,000 6,959E-04 0,01394011 ! skin development GO:0043588 11 11 1,000 7,397E-04 0,01465913 ! protein amino acid acetylation GO:0006473 11 11 1,000 7,397E-04 0,01450318 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 7,397E-04 0,01435052 ! digestive system process GO:0022600 11 11 1,000 7,397E-04 0,01420103 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 7,397E-04 0,01405463 ! G1/S transition checkpoint GO:0031575 12 11 1,000 7,397E-04 0,01391122 ! interaction with host GO:0051701 11 11 1,000 7,397E-04 0,0137707 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 7,397E-04 0,01363299 GO:0006109|regulation of carbohydrate metabolic process, ! positive regulation of MAP kinase activity GO:0043406 50 49 2,000 7,867E-04 0,01435567 ! regulation of DNA metabolic process GO:0051052 51 50 2,000 8,348E-04 0,01508443 ! regulation of neurogenesis GO:0050767 51 50 2,000 8,348E-04 0,01493798 ! negative regulation of peptidase activity GO:0010466 12 12 1,000 8,856E-04 0,01569384 ! somitogenesis GO:0001756 13 12 1,000 8,856E-04 0,01554438 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 8,856E-04 0,01539773 ! positive regulation of DNA replication GO:0045740 14 13 1,000 1,044E-03 0,01798539 ! mitochondrial membrane organization GO:0007006 13 13 1,000 1,044E-03 0,01781886 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 1,044E-03 0,01765539 ! negative regulation of DNA replication GO:0008156 13 13 1,000 1,044E-03 0,01749488 ! cell aging GO:0007569 13 13 1,000 1,044E-03 0,01733727 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 1,044E-03 0,01718247 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 1,044E-03 0,01703042 ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 1,000 1,044E-03 0,01688103 ! negative regulation of intracellular transport GO:0032387 13 13 1,000 1,044E-03 0,01673424 ! activation of JUN kinase activity GO:0007257 13 13 1,000 1,044E-03 0,01658998 ! regulation of nervous system development GO:0051960 57 56 2,000 1,163E-03 0,0183212 ! protein amino acid acylation GO:0043543 14 14 1,000 1,215E-03 0,01898275 ! macromolecular complex disassembly GO:0032984 15 14 1,000 1,215E-03 0,01882323 ! isoprenoid biosynthetic process GO:0008299 14 14 1,000 1,215E-03 0,01866637 ! base-excision repair GO:0006284 14 14 1,000 1,215E-03 0,0185121 ! regulation of binding GO:0051098 60 57 2,000 1,225E-03 0,01850008 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 1,354E-03 0,02028536 ! regulation of cell development GO:0060284 60 59 2,000 1,354E-03 0,02012177 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 1,399E-03 0,0206286 ! protein amino acid O-linked glycosylation GO:0006493 15 15 1,000 1,399E-03 0,02046488 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 1,399E-03 0,02030374 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 1,399E-03 0,02014512 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 1,399E-03 0,01998895 ! response to ionizing radiation GO:0010212 16 15 1,000 1,399E-03 0,01983519 ! cholesterol biosynthetic process GO:0006695 15 15 1,000 1,399E-03 0,01968378 ! regulation of synaptic plasticity GO:0048167 16 16 1,000 1,595E-03 0,02227352 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 1,595E-03 0,02210605 ! segmentation GO:0035282 17 16 1,000 1,595E-03 0,02194107 ! positive regulation of catabolic process GO:0009896 16 16 1,000 1,595E-03 0,02177855 ! regulation of JUN kinase activity GO:0043506 17 16 1,000 1,595E-03 0,02161841 GO:0043507|positive regulation of JUN kinase activity, ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 1,804E-03 0,0242656 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 1,000 1,804E-03 0,02408976 ! negative regulation of cell development GO:0010721 18 17 1,000 1,804E-03 0,02391645 GO:0050768|negative regulation of neurogenesis, ! regulation of MAP kinase activity GO:0043405 67 66 2,000 1,873E-03 0,02465088 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 2,025E-03 0,02646283 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 2,025E-03 0,02627647 ! cholesterol homeostasis GO:0042632 18 18 1,000 2,025E-03 0,02609272 GO:0055092|sterol homeostasis, ! negative regulation of DNA binding GO:0043392 19 18 1,000 2,025E-03 0,02591152 ! B cell differentiation GO:0030183 18 18 1,000 2,025E-03 0,02573282 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 2,025E-03 0,02555657 ! regionalization GO:0003002 70 69 2,000 2,128E-03 0,02667954 ! regulation of mitotic cell cycle GO:0007346 72 69 2,000 2,128E-03 0,02649927 ! DNA damage checkpoint GO:0000077 19 19 1,000 2,257E-03 0,02792321 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 2,257E-03 0,02773705 ! regulation of pH GO:0006885 19 19 1,000 2,257E-03 0,02755336 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 2,257E-03 0,02737209 ! hormone biosynthetic process GO:0042446 19 19 1,000 2,257E-03 0,02719319 ! biogenic amine biosynthetic process GO:0042401 20 19 1,000 2,257E-03 0,02701661 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 2,257E-03 0,02684231 ! negative regulation of binding GO:0051100 21 20 1,000 2,503E-03 0,02956489 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 2,503E-03 0,02937657 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 2,503E-03 0,02919065 ! female gamete generation GO:0007292 20 20 1,000 2,503E-03 0,02900706 ! cholesterol transport GO:0030301 21 21 1,000 2,76E-03 0,03178619 GO:0015918|sterol transport, ! DNA integrity checkpoint GO:0031570 21 21 1,000 2,76E-03 0,03158876 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 2,76E-03 0,03139376 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 2,76E-03 0,03120116 ! negative regulation of protein transport GO:0051224 21 21 1,000 2,76E-03 0,03101091 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 3,028E-03 0,03382667 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 3,028E-03 0,03362289 ! maintenance of protein location in cell GO:0032507 23 22 1,000 3,028E-03 0,03342156 ! ovulation cycle process GO:0022602 22 22 1,000 3,028E-03 0,03322262 ! sterol biosynthetic process GO:0016126 22 22 1,000 3,028E-03 0,03302604 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 1,000 3,028E-03 0,03283177 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 3,309E-03 0,03566547 ! female gonad development GO:0008585 23 23 1,000 3,309E-03 0,03545811 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 3,309E-03 0,03525315 ! lipid homeostasis GO:0055088 23 23 1,000 3,309E-03 0,03505054 ! regulation of JNK cascade GO:0046328 25 23 1,000 3,309E-03 0,03485026 ! cell projection assembly GO:0030031 25 23 1,000 3,309E-03 0,03465224 ! MAPKKK cascade GO:0000165 82 81 2,000 3,363E-03 0,03501519 ! lymphocyte activation GO:0046649 82 81 2,000 3,363E-03 0,03481848 ! mitochondrial transport GO:0006839 24 24 1,000 3,602E-03 0,03708276 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 1,000 3,602E-03 0,03687674 ! glucose homeostasis GO:0042593 24 24 1,000 3,602E-03 0,036673 GO:0033500|carbohydrate homeostasis, ! T cell differentiation GO:0030217 24 24 1,000 3,602E-03 0,0364715 ! ovulation cycle GO:0042698 24 24 1,000 3,602E-03 0,03627221 ! maintenance of protein location GO:0045185 25 24 1,000 3,602E-03 0,03607507 ! cellular component disassembly GO:0022411 26 25 1,000 3,906E-03 0,03890973 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 3,906E-03 0,03870053 ! development of primary female sexual characteristics GO:0046545 25 25 1,000 3,906E-03 0,03849358 GO:0046660|female sex differentiation, ! positive regulation of DNA binding GO:0043388 26 25 1,000 3,906E-03 0,03828883 ! heart morphogenesis GO:0003007 25 25 1,000 3,906E-03 0,03808624 ! positive regulation of protein kinase activity GO:0045860 89 86 2,000 3,984E-03 0,03864047 ! heart development GO:0007507 90 87 2,000 4,116E-03 0,03971158 ! positive regulation of binding GO:0051099 27 26 1,000 4,221E-03 0,04052133 ! double-strand break repair GO:0006302 27 26 1,000 4,221E-03 0,04031137 ! response to insulin stimulus GO:0032868 28 26 1,000 4,221E-03 0,04010358 ! maintenance of location in cell GO:0051651 27 26 1,000 4,221E-03 0,03989792 ! positive regulation of transferase activity GO:0051347 91 88 2,000 4,25E-03 0,03996435 GO:0033674|positive regulation of kinase activity, ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 4,549E-03 0,04255352 ! activation of caspase activity GO:0006919 27 27 1,000 4,549E-03 0,0423386 ! isoprenoid metabolic process GO:0006720 27 27 1,000 4,549E-03 0,04212584 ! cell growth GO:0016049 27 27 1,000 4,549E-03 0,04191521 ! negative regulation of cell cycle GO:0045786 92 91 2,000 4,67E-03 0,04282039 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 1,000 4,887E-03 0,04458905 GO:0007254|JNK cascade, ! keratinocyte differentiation GO:0030216 28 28 1,000 4,887E-03 0,0443694 ! histone modification GO:0016570 28 28 1,000 4,887E-03 0,0441519 ! pattern specification process GO:0007389 96 94 2,000 5,114E-03 0,04597931 ! viral reproductive process GO:0022415 29 29 1,000 5,237E-03 0,04685329 ! covalent chromatin modification GO:0016569 29 29 1,000 5,237E-03 0,04662694 ! response to UV GO:0009411 29 29 1,000 5,237E-03 0,04640277 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 5,598E-03 0,04936485 GO:0043280|positive regulation of caspase activity, ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 1,000 5,598E-03 0,04912978 ! lipoprotein metabolic process GO:0042157 31 31 1,000 5,97E-03 0,05214818 ! aging GO:0007568 32 31 1,000 5,97E-03 0,0519022 ! digestion GO:0007586 31 31 1,000 5,97E-03 0,05165853 ! regulation of intracellular transport GO:0032386 31 31 1,000 5,97E-03 0,05141713 ! epidermal cell differentiation GO:0009913 31 31 1,000 5,97E-03 0,05117798 ! response to hormone stimulus GO:0009725 102 100 2,000 6,078E-03 0,05185815 ! negative regulation of cell growth GO:0030308 32 32 1,000 6,354E-03 0,05396158 ! maintenance of location GO:0051235 33 32 1,000 6,354E-03 0,05371405 ! negative regulation of cell size GO:0045792 33 33 1,000 6,748E-03 0,05678671 ! regulation of cellular response to stress GO:0080135 35 33 1,000 6,748E-03 0,05652859 ! regulation of neuron differentiation GO:0045664 34 33 1,000 6,748E-03 0,0562728 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 6,748E-03 0,05601932 ! regulation of synaptic transmission GO:0050804 33 33 1,000 6,748E-03 0,05576811 ! viral reproduction GO:0016032 34 34 1,000 7,153E-03 0,05885267 ! multicellular organism reproduction GO:0032504 36 35 1,000 7,569E-03 0,06199838 GO:0048609|reproductive process in a multicellular organism, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 1,000 7,996E-03 0,06520378 ! regulation of transmission of nerve impulse GO:0051969 36 36 1,000 7,996E-03 0,06491654 ! gonad development GO:0008406 36 36 1,000 7,996E-03 0,06463182 ! regulation of mitosis GO:0007088 37 36 1,000 7,996E-03 0,06434958 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 36 36 1,000 7,996E-03 0,0640698 ! regulation of transcription factor activity GO:0051090 38 37 1,000 8,433E-03 0,06728185 GO:0090046|regulation of transcription regulator activity, ! lung development GO:0030324 38 37 1,000 8,433E-03 0,06699184 ! negative regulation of growth GO:0045926 37 37 1,000 8,433E-03 0,06670432 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 8,433E-03 0,06641926 ! cellular hormone metabolic process GO:0034754 39 38 1,000 8,881E-03 0,06964954 ! urogenital system development GO:0001655 38 38 1,000 8,881E-03 0,06935442 ! RNA elongation GO:0006354 38 38 1,000 8,881E-03 0,06906178 ! regulation of neurological system process GO:0031644 38 38 1,000 8,881E-03 0,06877161 ! respiratory system development GO:0060541 40 39 1,000 9,339E-03 0,0720189 ! lymphocyte differentiation GO:0030098 39 39 1,000 9,339E-03 0,07171882 ! positive regulation of cell motion GO:0051272 39 39 1,000 9,339E-03 0,07142123 ! respiratory tube development GO:0030323 40 39 1,000 9,339E-03 0,0711261 ! regulation of MAPKKK cascade GO:0043408 41 39 1,000 9,339E-03 0,0708334 ! DNA catabolic process GO:0006308 41 40 1,000 9,808E-03 0,07408436 ! cell cycle checkpoint GO:0000075 42 41 1,000 0,01028741 0,07738651 ! development of primary sexual characteristics GO:0045137 42 42 1,000 0,01077684 0,08073865 ! protein import into nucleus GO:0006606 44 44 1,000 0,01178614 0,08794276 ! amine biosynthetic process GO:0009309 46 45 1,000 0,01230587 0,09145048 ! steroid biosynthetic process GO:0006694 46 45 1,000 0,01230587 0,0910832 ! nuclear import GO:0051170 45 45 1,000 0,01230587 0,09071887 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 1,000 0,01283554 0,09424663 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 0,01283554 0,09387263 ! regulation of catabolic process GO:0009894 48 47 1,000 0,01337508 0,09743193 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,01392442 0,10103425 ! protein localization in nucleus GO:0034504 48 48 1,000 0,01392442 0,10063804 ! leukocyte differentiation GO:0002521 50 49 1,000 0,01448347 0,10426965 ! gland development GO:0048732 51 49 1,000 0,01448347 0,10386393 ! cell cycle arrest GO:0007050 49 49 1,000 0,01448347 0,10346136 ! skeletal muscle tissue development GO:0007519 50 49 1,000 0,01448347 0,10306189 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 1,000 0,01448347 0,1026655 ! negative regulation of transport GO:0051051 51 50 1,000 0,01505216 0,10628786 ! T cell activation GO:0042110 51 50 1,000 0,01505216 0,10588218 ! transcription initiation GO:0006352 50 50 1,000 0,01505216 0,10547959 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,01505216 0,10508004 ! biogenic amine metabolic process GO:0006576 52 51 1,000 0,01563042 0,10870515 ! cell fate commitment GO:0045165 52 52 1,000 0,01621817 0,11236876 ! response to light stimulus GO:0009416 53 52 1,000 0,01621817 0,1119479 ! response to hypoxia GO:0001666 53 53 1,000 0,01681534 0,11563685 ! regulation of protein transport GO:0051223 53 53 1,000 0,01681534 0,11520697 GO:0070201|regulation of establishment of protein localization, ! response to oxygen levels GO:0070482 55 54 1,000 0,01742186 0,1189203 ! hormone metabolic process GO:0042445 55 54 1,000 0,01742186 0,11848148 ! in utero embryonic development GO:0001701 55 55 1,000 0,01803764 0,12221828 ! rRNA transcription GO:0009303 5 5 0,000 0,01875849 0,12663696 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,01875849 0,12617478 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,01875849 0,12571597 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,01875849 0,12526047 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,01875849 0,12480827 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,01875849 0,12435932 ! reproductive cellular process GO:0048610 5 5 0,000 0,01875849 0,12391359 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,01875849 0,12347104 ! metencephalon development GO:0022037 5 5 0,000 0,01875849 0,12303164 ! water transport GO:0006833 5 5 0,000 0,01875849 0,12259536 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,01875849 0,12216216 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,01875849 0,12173201 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,01875849 0,12130488 ! glycerol metabolic process GO:0006071 5 5 0,000 0,01875849 0,12088074 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,01875849 0,12045955 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,01875849 0,12004129 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,01875849 0,11962592 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,01875849 0,11921342 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,01875849 0,11880375 ! filopodium assembly GO:0046847 7 5 0,000 0,01875849 0,11839689 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,01875849 0,1179928 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,01875849 0,11759146 ! GTP metabolic process GO:0046039 5 5 0,000 0,01875849 0,11719285 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,01875849 0,11679693 ! mRNA stabilization GO:0048255 5 5 0,000 0,01875849 0,11640367 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,01875849 0,11601306 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,01875849 0,11562505 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,01875849 0,11523964 ! social behavior GO:0035176 5 5 0,000 0,01875849 0,11485678 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,01875849 0,11447646 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,01875849 0,11409865 ! memory GO:0007613 5 5 0,000 0,01875849 0,11372332 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,01875849 0,11335046 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,01875849 0,11298003 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,01875849 0,11261202 ! response to lipid GO:0033993 5 5 0,000 0,01875849 0,1122464 ! erythrocyte maturation GO:0043249 5 5 0,000 0,01875849 0,11188314 ! hippocampus development GO:0021766 6 5 0,000 0,01875849 0,11152223 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,01875849 0,11116364 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,01875849 0,11080734 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,01875849 0,11045332 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,01875849 0,11010156 ! mechanosensory behavior GO:0007638 5 5 0,000 0,01875849 0,10975203 ! heart looping GO:0001947 5 5 0,000 0,01875849 0,10940472 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,01875849 0,10905959 ! response to interferon-gamma GO:0034341 5 5 0,000 0,01875849 0,10871664 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,01875849 0,10837583 ! endocrine pancreas development GO:0031018 5 5 0,000 0,01875849 0,10803716 ! pH reduction GO:0045851 5 5 0,000 0,01875849 0,10770059 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,01875849 0,10736612 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,01875849 0,10703372 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,01875849 0,10670337 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,01875849 0,10637505 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,01875849 0,10604874 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,01875849 0,10572444 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,01875849 0,10540211 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,01875849 0,10508173 ! adrenal gland development GO:0030325 5 5 0,000 0,01875849 0,1047633 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,01875849 0,1044468 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,01875849 0,1041322 GO:0050931|pigment cell differentiation, ! astrocyte differentiation GO:0048708 5 5 0,000 0,01875849 0,10381949 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,01875849 0,10350865 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,01875849 0,10319967 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,01875849 0,10289253 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,01875849 0,10258721 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,01875849 0,1022837 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,01875849 0,10198198 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,01875849 0,10168203 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,01875849 0,10138384 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,01875849 0,1010874 ! muscle cell migration GO:0014812 5 5 0,000 0,01875849 0,10079268 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,01875849 0,10049968 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,01875849 0,10020838 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,01875849 0,09991876 ! response to ATP GO:0033198 5 5 0,000 0,01875849 0,09963081 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,01875849 0,09934451 ! regulation of appetite GO:0032098 5 5 0,000 0,01875849 0,09905986 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,01875849 0,09877683 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,01875849 0,09849541 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,01875849 0,0982156 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,01875849 0,09793737 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,01875849 0,09766071 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01875849 0,09738561 ! receptor clustering GO:0043113 5 5 0,000 0,01875849 0,09711205 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,01875849 0,09684003 ! fear response GO:0042596 5 5 0,000 0,01875849 0,09656953 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,01875849 0,09630053 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,01875849 0,09603303 ! retinol metabolic process GO:0042572 5 5 0,000 0,01875849 0,09576701 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,01875849 0,09550246 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,01875849 0,09523937 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,01875849 0,09497772 ! parturition GO:0007567 5 5 0,000 0,01875849 0,09471751 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01875849 0,09445872 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,01875849 0,09420134 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,01875849 0,09394535 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,01875849 0,09369076 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,01875849 0,09343754 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,01875849 0,09318569 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,01875849 0,09293519 ! response to UV-B GO:0010224 5 5 0,000 0,01875849 0,09268603 ! oligodendrocyte development GO:0014003 5 5 0,000 0,01875849 0,09243821 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,01875849 0,09219171 ! activated T cell proliferation GO:0050798 5 5 0,000 0,01875849 0,09194652 ! interaction with symbiont GO:0051702 5 5 0,000 0,01875849 0,09170263 ! cellular extravasation GO:0045123 5 5 0,000 0,01875849 0,09146003 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,01875849 0,09121871 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,01875849 0,09097866 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,01875849 0,09073987 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,01875849 0,09050233 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,01875849 0,09026603 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,01875849 0,09003096 ! response to amine stimulus GO:0014075 5 5 0,000 0,01875849 0,08979712 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,01875849 0,08956448 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,01875849 0,08933305 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,01875849 0,08910281 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,01875849 0,08887375 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,01875849 0,08864587 ! neuron recognition GO:0008038 5 5 0,000 0,01875849 0,08841916 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,01875849 0,0881936 ! decidualization GO:0046697 5 5 0,000 0,01875849 0,08796919 ! hair follicle maturation GO:0048820 5 5 0,000 0,01875849 0,08774592 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,01875849 0,08752377 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,01875849 0,08730275 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,01875849 0,08708285 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,01875849 0,08686405 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,01875849 0,08664634 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,01875849 0,08642973 ! postreplication repair GO:0006301 5 5 0,000 0,01875849 0,08621419 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,01875849 0,08599973 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,01875849 0,08578633 ! histone methylation GO:0016571 5 5 0,000 0,01875849 0,08557399 ! DNA methylation GO:0006306 5 5 0,000 0,01875849 0,08536269 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01875849 0,08515244 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,01875849 0,08494322 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,01875849 0,08473503 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,01875849 0,08452785 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,01875849 0,08432168 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,01875849 0,08411652 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,01875849 0,08391236 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,01875849 0,08370918 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,01875849 0,08350698 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,01875849 0,08330576 ! sterol catabolic process GO:0016127 5 5 0,000 0,01875849 0,08310551 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,01875849 0,08290621 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,01875849 0,08270787 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,01875849 0,08251048 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,01875849 0,08231403 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,01875849 0,0821185 ! zymogen activation GO:0031638 5 5 0,000 0,01875849 0,08192391 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,01875849 0,08173024 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,01875849 0,08153748 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,01875849 0,08134562 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,01875849 0,08115467 ! nucleosome positioning GO:0016584 5 5 0,000 0,01875849 0,08096461 ! regulation of isotype switching GO:0045191 5 5 0,000 0,01875849 0,08077545 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,01875849 0,08058716 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,01875849 0,08039975 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,01875849 0,0802132 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,01875849 0,08002752 ! NADPH regeneration GO:0006740 5 5 0,000 0,01875849 0,0798427 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,01875849 0,07965873 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,01875849 0,07947561 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,01875849 0,07929333 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,01875849 0,07911188 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,01875849 0,07893126 ! sarcomere organization GO:0045214 5 5 0,000 0,01875849 0,07875146 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,01875849 0,07857248 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,01875849 0,07839431 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,01875849 0,07821695 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,01875849 0,07804038 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,01875849 0,07786462 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,01875849 0,07768964 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,01875849 0,07751545 ! spleen development GO:0048536 5 5 0,000 0,01875849 0,07734204 ! male genitalia development GO:0030539 5 5 0,000 0,01875849 0,0771694 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,01875849 0,07699753 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,01875849 0,07682642 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,01875849 0,07665608 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,01875849 0,07648648 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,01875849 0,07631764 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,01875849 0,07614954 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,01875849 0,07598218 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,01875849 0,07581555 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,01875849 0,07564965 ! ATP catabolic process GO:0006200 5 5 0,000 0,01875849 0,07548448 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01875849 0,07532002 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,01875849 0,07515628 ! blastocyst formation GO:0001825 5 5 0,000 0,01875849 0,07499325 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,01875849 0,07483093 ! embryonic gut development GO:0048566 5 5 0,000 0,01875849 0,07466931 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,01875849 0,07450838 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,01875849 0,07434815 ! activation of innate immune response GO:0002218 5 5 0,000 0,01875849 0,07418861 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,01875849 0,07402974 ! catecholamine transport GO:0051937 5 5 0,000 0,01875849 0,07387156 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,01875849 0,07371405 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,01875849 0,07355721 ! muscle adaptation GO:0043500 5 5 0,000 0,01875849 0,07340104 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,01875849 0,07324553 ! embryonic heart tube development GO:0035050 5 5 0,000 0,01875849 0,07309068 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,01875849 0,07293648 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,01875849 0,07278293 ! defense response to fungus GO:0050832 5 5 0,000 0,01875849 0,07263002 ! lysogeny GO:0030069 5 5 0,000 0,01875849 0,07247776 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,01875849 0,07232613 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,01875849 0,07217514 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,01875849 0,07202477 ! response to nicotine GO:0035094 5 5 0,000 0,01875849 0,07187503 ! establishment of cell polarity GO:0030010 5 5 0,000 0,01875849 0,07172591 ! mitochondrion localization GO:0051646 5 5 0,000 0,01875849 0,07157741 ! nucleus localization GO:0051647 5 5 0,000 0,01875849 0,07142953 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,01875849 0,07128225 ! regulation of protein localization GO:0032880 58 57 1,000 0,01929673 0,07317671 ! cellular aromatic compound metabolic process GO:0006725 60 59 1,000 0,02059204 0,07792839 ! protein localization in organelle GO:0033365 59 59 1,000 0,02059204 0,0777687 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,02192298 0,08262588 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,02246936 0,08451232 ! axon extension GO:0048675 7 6 0,000 0,02246936 0,0843402 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,02246936 0,08416877 ! tRNA modification GO:0006400 6 6 0,000 0,02246936 0,08399805 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,02246936 0,08382801 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,02246936 0,08365866 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,02246936 0,08348999 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,02246936 0,08332201 ! regulation of S phase GO:0033261 6 6 0,000 0,02246936 0,08315469 ! myotube differentiation GO:0014902 6 6 0,000 0,02246936 0,08298805 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,02246936 0,08282207 ! bone remodeling GO:0046849 6 6 0,000 0,02246936 0,08265676 ! N-glycan processing GO:0006491 6 6 0,000 0,02246936 0,08249211 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,02246936 0,08232811 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,02246936 0,08216476 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,02246936 0,08200205 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,02246936 0,08183999 ! RNA methylation GO:0001510 6 6 0,000 0,02246936 0,08167857 ! cartilage condensation GO:0001502 7 6 0,000 0,02246936 0,08151779 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,02246936 0,08135764 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,02246936 0,08119811 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,02246936 0,08103921 ! artery development GO:0060840 6 6 0,000 0,02246936 0,08088093 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,02246936 0,08072327 ! bile acid metabolic process GO:0008206 6 6 0,000 0,02246936 0,08056622 ! androgen metabolic process GO:0008209 6 6 0,000 0,02246936 0,08040978 ! estrogen metabolic process GO:0008210 6 6 0,000 0,02246936 0,08025395 ! limbic system development GO:0021761 7 6 0,000 0,02246936 0,08009872 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,02246936 0,07994409 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,02246936 0,07979005 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,02246936 0,07963661 ! pathogenesis GO:0009405 6 6 0,000 0,02246936 0,07948376 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,02246936 0,07933149 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,02246936 0,0791798 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,02246936 0,0790287 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,02246936 0,07887817 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,02246936 0,07872821 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,02246936 0,07857882 ! arginine metabolic process GO:0006525 6 6 0,000 0,02246936 0,07842999 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,02246936 0,07828173 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,02246936 0,07813403 ! glutamate catabolic process GO:0006538 7 6 0,000 0,02246936 0,07798689 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,02246936 0,07784029 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,02246936 0,07769425 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,02246936 0,07754876 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,02246936 0,07740381 ! V(D)J recombination GO:0033151 6 6 0,000 0,02246936 0,0772594 ! focal adhesion formation GO:0048041 7 6 0,000 0,02246936 0,07711552 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,02246936 0,07697219 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 0,02246936 0,07682938 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,02246936 0,07668711 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,02246936 0,07654535 ! regulation of heart rate GO:0002027 6 6 0,000 0,02246936 0,07640413 ! asymmetric protein localization GO:0008105 6 6 0,000 0,02246936 0,07626342 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,02246936 0,07612323 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,02246936 0,07598355 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,02246936 0,07584439 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,02246936 0,07570573 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,02246936 0,07556759 ! ruffle organization GO:0031529 6 6 0,000 0,02246936 0,07542994 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,02246936 0,07529279 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,02246936 0,07515615 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,02246936 0,07501999 ! neutral amino acid transport GO:0015804 6 6 0,000 0,02246936 0,07488433 ! L-amino acid transport GO:0015807 6 6 0,000 0,02246936 0,07474916 ! bone mineralization GO:0030282 6 6 0,000 0,02246936 0,07461448 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,02246936 0,07448028 ! negative regulation of ossification GO:0030279 6 6 0,000 0,02246936 0,07434657 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,02246936 0,07421333 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,02246936 0,07408057 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,02246936 0,07394828 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,02246936 0,07381646 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,02246936 0,07368512 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,02246936 0,07355424 ! regulation of organ growth GO:0046620 6 6 0,000 0,02246936 0,07342382 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,02246936 0,07329387 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,02246936 0,07316438 ! response to dsRNA GO:0043331 6 6 0,000 0,02246936 0,07303534 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,02246936 0,07290676 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,02246936 0,07277862 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 0,02246936 0,07265094 ! genitalia development GO:0048806 6 6 0,000 0,02246936 0,07252371 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,02246936 0,07239692 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,02246936 0,07227057 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 0,02246936 0,07214466 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,02246936 0,07201919 ! multicellular organismal aging GO:0010259 6 6 0,000 0,02246936 0,07189416 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,02246936 0,07176956 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,02246936 0,07164539 ! erythrocyte development GO:0048821 6 6 0,000 0,02246936 0,07152165 ! renal water homeostasis GO:0003091 6 6 0,000 0,02246936 0,07139834 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,02246936 0,07127545 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,02246936 0,07115298 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,02246936 0,07103094 ! ribosome assembly GO:0042255 6 6 0,000 0,02246936 0,07090931 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,02246936 0,0707881 ! diencephalon development GO:0021536 6 6 0,000 0,02246936 0,0706673 ! fucose catabolic process GO:0019317 6 6 0,000 0,02246936 0,07054691 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,02246936 0,07042693 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,02246936 0,07030736 ! regulation of lipid transport GO:0032368 6 6 0,000 0,02246936 0,0701882 ! regulation of cell division GO:0051302 6 6 0,000 0,02246936 0,07006944 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,02246936 0,06995108 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,02246936 0,06983311 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,02246936 0,06971555 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,02246936 0,06959838 ! neuroblast proliferation GO:0007405 6 6 0,000 0,02246936 0,06948161 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,02246936 0,06936522 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,02246936 0,06924923 ! regulation of glucose transport GO:0010827 6 6 0,000 0,02246936 0,06913362 GO:0046324|regulation of glucose import, ! methionine biosynthetic process GO:0009086 6 6 0,000 0,02246936 0,06901839 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,02246936 0,06890356 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,02246936 0,0687891 ! thymus development GO:0048538 6 6 0,000 0,02246936 0,06867502 ! lymph node development GO:0048535 6 6 0,000 0,02246936 0,06856132 ! organic cation transport GO:0015695 6 6 0,000 0,02246936 0,06844799 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,02246936 0,06833504 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,02246936 0,06822247 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,02246936 0,06811026 ! sperm-egg recognition GO:0035036 7 6 0,000 0,02246936 0,06799842 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,02246936 0,06788695 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,02246936 0,06777584 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,02246936 0,06766509 ! alditol metabolic process GO:0019400 6 6 0,000 0,02246936 0,06755471 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,02246936 0,06744469 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,02246936 0,06733502 ! maternal placenta development GO:0001893 6 6 0,000 0,02246936 0,06722571 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,02246936 0,06711675 ! localization within membrane GO:0051668 6 6 0,000 0,02246936 0,06700815 ! lipid transport GO:0006869 62 62 1,000 0,02260164 0,06729374 ! protein import GO:0017038 62 62 1,000 0,02260164 0,0671852 ! angiogenesis GO:0001525 65 64 1,000 0,02398498 0,07118248 ! regulation of hormone levels GO:0010817 66 65 1,000 0,02468952 0,07315561 ! protein amino acid glycosylation GO:0006486 66 66 1,000 0,02540255 0,07514752 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! striated muscle tissue development GO:0014706 69 67 1,000 0,026124 0,07715791 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,026124 0,07703446 ! respiratory burst GO:0045730 7 7 0,000 0,02616674 0,07703724 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,02616674 0,07691437 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,02616674 0,07679189 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,02616674 0,07666981 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,02616674 0,07654811 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,02616674 0,0764268 ! regulation of chemokine production GO:0032642 7 7 0,000 0,02616674 0,07630587 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,02616674 0,07618532 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,02616674 0,07606516 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,02616674 0,07594537 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,02616674 0,07582596 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,02616674 0,07570692 ! gene silencing by RNA GO:0031047 7 7 0,000 0,02616674 0,07558826 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,02616674 0,07546997 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,02616674 0,07535205 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,02616674 0,07523449 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,02616674 0,07511731 ! visual behavior GO:0007632 7 7 0,000 0,02616674 0,07500048 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,02616674 0,07488402 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,02616674 0,07476792 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,02616674 0,07465218 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,02616674 0,0745368 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,02616674 0,07442177 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,02616674 0,0743071 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,02616674 0,07419278 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,02616674 0,07407882 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,02616674 0,0739652 ! digestive system development GO:0055123 7 7 0,000 0,02616674 0,07385193 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,02616674 0,07373901 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,02616674 0,07362643 ! protein targeting to ER GO:0045047 8 7 0,000 0,02616674 0,07351419 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,02616674 0,0734023 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,02616674 0,07329074 ! endoderm development GO:0007492 7 7 0,000 0,02616674 0,07317953 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,02616674 0,07306865 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,02616674 0,07295811 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,02616674 0,0728479 ! response to hexose stimulus GO:0009746 7 7 0,000 0,02616674 0,07273802 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,02616674 0,07262848 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,02616674 0,07251926 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,02616674 0,07241038 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 0,02616674 0,07230181 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,02616674 0,07219358 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,02616674 0,07208567 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,02616674 0,07197807 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,02616674 0,0718708 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,02616674 0,07176385 ! UV protection GO:0009650 7 7 0,000 0,02616674 0,07165722 ! DNA integration GO:0015074 7 7 0,000 0,02616674 0,0715509 ! myofibril assembly GO:0030239 7 7 0,000 0,02616674 0,0714449 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,02616674 0,07133922 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,02616674 0,07123384 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,02616674 0,07112878 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,02616674 0,07102402 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,02616674 0,07091957 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,02616674 0,07081543 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,02616674 0,0707116 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,02616674 0,07060807 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,02616674 0,07050484 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,02616674 0,07040191 ! axon cargo transport GO:0008088 7 7 0,000 0,02616674 0,07029929 ! eating behavior GO:0042755 7 7 0,000 0,02616674 0,07019696 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,02616674 0,07009493 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,02616674 0,06999319 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,02616674 0,06989175 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,02616674 0,06979061 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,02616674 0,06968975 ! cranial nerve development GO:0021545 7 7 0,000 0,02616674 0,06958919 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,02616674 0,06948892 ! induction of an organ GO:0001759 7 7 0,000 0,02616674 0,06938894 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,02616674 0,06928924 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,02616674 0,06918983 ! autonomic nervous system development GO:0048483 7 7 0,000 0,02616674 0,0690907 ! intracellular lipid transport GO:0032365 7 7 0,000 0,02616674 0,06899186 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,02616674 0,0688933 ! platelet activation GO:0030168 8 7 0,000 0,02616674 0,06879502 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,02616674 0,06869702 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,02616674 0,0685993 ! natural killer cell activation GO:0030101 7 7 0,000 0,02616674 0,06850186 ! NADP metabolic process GO:0006739 7 7 0,000 0,02616674 0,06840469 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,02616674 0,0683078 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,02616674 0,06821119 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,02616674 0,06811484 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,02616674 0,06801877 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,02616674 0,06792297 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,02616674 0,06782744 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,02616674 0,06773218 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,02616674 0,06763718 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,02616674 0,06754245 ! cell-cell recognition GO:0009988 8 7 0,000 0,02616674 0,06744799 ! hormone catabolic process GO:0042447 7 7 0,000 0,02616674 0,06735378 ! dopamine metabolic process GO:0042417 7 7 0,000 0,02616674 0,06725985 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,02616674 0,06716617 ! oxygen transport GO:0015671 7 7 0,000 0,02616674 0,06707275 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,02616674 0,0669796 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,02616674 0,0668867 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,02616674 0,06679406 ! regulation of axon extension GO:0030516 7 7 0,000 0,02616674 0,06670167 ! cell killing GO:0001906 7 7 0,000 0,02616674 0,06660954 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,02616674 0,06651767 ! adult feeding behavior GO:0008343 7 7 0,000 0,02616674 0,06642605 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,02616674 0,06633468 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,02616674 0,06624356 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,02616674 0,06615269 ! negative regulation of T cell activation GO:0050868 7 7 0,000 0,02616674 0,06606207 ! response to cold GO:0009409 7 7 0,000 0,02616674 0,0659717 ! response to radiation GO:0009314 70 68 1,000 0,0268538 0,06761142 ! growth GO:0040007 70 70 1,000 0,02833819 0,0712514 ! muscle tissue development GO:0060537 72 70 1,000 0,02833819 0,07115433 ! regulation of cell migration GO:0030334 71 71 1,000 0,02909263 0,07294928 ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,02909263 0,07285016 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,02985068 0,07464694 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,02985068 0,07454579 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,02985068 0,07444492 ! positive regulation of translation GO:0045727 8 8 0,000 0,02985068 0,07434432 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,02985068 0,07424399 ! superoxide anion generation GO:0042554 8 8 0,000 0,02985068 0,07414393 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,02985068 0,07404414 ! cGMP metabolic process GO:0046068 8 8 0,000 0,02985068 0,07394462 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,02985068 0,07384536 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,02985068 0,07374638 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,02985068 0,07364765 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,02985068 0,07354919 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,02985068 0,073451 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,02985068 0,07335306 ! zinc ion transport GO:0006829 8 8 0,000 0,02985068 0,07325539 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,02985068 0,07315797 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,02985068 0,07306082 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,02985068 0,07296392 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,02985068 0,07286728 ! response to pain GO:0048265 8 8 0,000 0,02985068 0,07277089 ! response to cAMP GO:0051591 8 8 0,000 0,02985068 0,07267476 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,02985068 0,07257889 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,02985068 0,07248326 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,02985068 0,07238789 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,02985068 0,07229277 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,02985068 0,0721979 ! sensory perception of taste GO:0050909 8 8 0,000 0,02985068 0,07210327 ! organelle fusion GO:0048284 8 8 0,000 0,02985068 0,0720089 ! pancreas development GO:0031016 8 8 0,000 0,02985068 0,07191477 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,02985068 0,07182088 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,02985068 0,07172724 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,02985068 0,07163385 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,02985068 0,0715407 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,02985068 0,07144779 ! sperm motility GO:0030317 8 8 0,000 0,02985068 0,07135512 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,02985068 0,07126269 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,02985068 0,0711705 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,02985068 0,07107855 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,02985068 0,07098683 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,02985068 0,07089536 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,02985068 0,07080411 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,02985068 0,07071311 ! Golgi organization GO:0007030 8 8 0,000 0,02985068 0,07062233 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,02985068 0,07053179 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,02985068 0,07044148 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,02985068 0,0703514 ! fructose metabolic process GO:0006000 8 8 0,000 0,02985068 0,07026155 ! mannose metabolic process GO:0006013 9 8 0,000 0,02985068 0,07017193 ! NAD metabolic process GO:0019674 8 8 0,000 0,02985068 0,07008254 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,02985068 0,06999338 ! plasma membrane fusion GO:0045026 8 8 0,000 0,02985068 0,06990444 ! response to fungus GO:0009620 8 8 0,000 0,02985068 0,06981573 ! stem cell differentiation GO:0048863 8 8 0,000 0,02985068 0,06972725 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,02985068 0,06963898 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,02985068 0,06955094 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,02985068 0,06946313 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,02985068 0,06937553 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,02985068 0,06928816 ! regulation of vasodilation GO:0042312 8 8 0,000 0,02985068 0,069201 ! vasoconstriction GO:0042310 8 8 0,000 0,02985068 0,06911407 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,02985068 0,06902735 ! muscle cell development GO:0055001 8 8 0,000 0,02985068 0,06894085 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,02985068 0,06885456 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,02985068 0,0687685 ! sensory perception of pain GO:0019233 8 8 0,000 0,02985068 0,06868264 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,02985068 0,068597 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,02985068 0,06851158 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,02985068 0,06842636 ! chromatin silencing GO:0006342 8 8 0,000 0,02985068 0,06834136 ! tissue regeneration GO:0042246 8 8 0,000 0,02985068 0,06825657 ! salivary gland development GO:0007431 8 8 0,000 0,02985068 0,06817199 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,02985068 0,06808762 ! T cell homeostasis GO:0043029 8 8 0,000 0,02985068 0,06800346 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,02985068 0,0679195 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,02985068 0,06783575 ! water homeostasis GO:0030104 8 8 0,000 0,02985068 0,06775221 ! cofactor transport GO:0051181 8 8 0,000 0,02985068 0,06766888 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,02985068 0,06758575 ! acid secretion GO:0046717 8 8 0,000 0,02985068 0,06750282 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,02985068 0,06742009 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,02985068 0,06733757 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,02985068 0,06725525 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,02985068 0,06717313 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,02985068 0,06709122 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,02985068 0,0670095 ! regulation of RNA stability GO:0043487 8 8 0,000 0,02985068 0,06692798 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,02985068 0,06684665 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,02985068 0,06676553 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,02985068 0,0666846 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,02985068 0,06660387 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,02985068 0,06652333 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,02985068 0,06644299 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,02985068 0,06636284 ! developmental induction GO:0031128 8 8 0,000 0,02985068 0,06628289 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,02985068 0,06620312 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,02985068 0,06612355 ! actin filament polymerization GO:0030041 9 8 0,000 0,02985068 0,06604417 ! peptide hormone processing GO:0016486 8 8 0,000 0,02985068 0,06596498 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,02985068 0,06588598 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,02985068 0,06580717 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,02985516 0,06573842 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,03298474 0,07254282 ! lactation GO:0007595 10 9 0,000 0,03352121 0,07363478 ! embryonic pattern specification GO:0009880 10 9 0,000 0,03352121 0,07354712 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,03352121 0,07345967 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,03352121 0,07337243 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,03352121 0,07328539 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,03352121 0,07319856 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,03352121 0,07311193 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,03352121 0,07302551 ! viral genome replication GO:0019079 9 9 0,000 0,03352121 0,0729393 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,03352121 0,07285328 ! copper ion transport GO:0006825 9 9 0,000 0,03352121 0,07276747 ! lipid phosphorylation GO:0046834 9 9 0,000 0,03352121 0,07268186 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,03352121 0,07259646 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,03352121 0,07251125 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,03352121 0,07242624 ! RNA polyadenylation GO:0043631 9 9 0,000 0,03352121 0,07234143 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,03352121 0,07225682 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,03352121 0,07217241 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,03352121 0,0720882 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,03352121 0,07200418 ! phospholipid efflux GO:0033700 9 9 0,000 0,03352121 0,07192035 ! response to alkaloid GO:0043279 10 9 0,000 0,03352121 0,07183672 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,03352121 0,07175329 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,03352121 0,07167005 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,03352121 0,071587 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,03352121 0,07150415 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,03352121 0,07142148 ! response to ethanol GO:0045471 9 9 0,000 0,03352121 0,07133901 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,03352121 0,07125673 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,03352121 0,07117464 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,03352121 0,07109273 ! methionine metabolic process GO:0006555 9 9 0,000 0,03352121 0,07101102 ! glutamine metabolic process GO:0006541 9 9 0,000 0,03352121 0,07092949 ! cerebral cortex development GO:0021987 9 9 0,000 0,03352121 0,07084815 ! response to osmotic stress GO:0006970 9 9 0,000 0,03352121 0,07076699 ! pigmentation during development GO:0048066 9 9 0,000 0,03352121 0,07068602 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,03352121 0,07060524 ! central nervous system neuron development GO:0021954 10 9 0,000 0,03352121 0,07052464 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,03352121 0,07044422 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,03352121 0,07036399 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,03352121 0,07028394 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,03352121 0,07020407 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,03352121 0,07012439 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,03352121 0,07004488 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,03352121 0,06996555 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,03352121 0,06988641 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,03352121 0,06980744 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,03352121 0,06972865 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,03352121 0,06965004 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,03352121 0,0695716 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,03352121 0,06949334 ! DNA replication initiation GO:0006270 9 9 0,000 0,03352121 0,06941526 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,03352121 0,06933736 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,03352121 0,06925962 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,03352121 0,06918206 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,03352121 0,06910468 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,03352121 0,06902747 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,03352121 0,06895043 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,03352121 0,06887356 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,03352121 0,06879686 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,03352121 0,06872034 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,03352121 0,06864398 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,03352121 0,0685678 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,03352121 0,06849178 ! collagen catabolic process GO:0030574 9 9 0,000 0,03352121 0,06841593 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,03352121 0,06834025 ! purine base metabolic process GO:0006144 9 9 0,000 0,03352121 0,06826473 ! gas transport GO:0015669 9 9 0,000 0,03352121 0,06818939 ! cholesterol efflux GO:0033344 9 9 0,000 0,03352121 0,0681142 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,03352121 0,06803919 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,03352121 0,06796434 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,03352121 0,06788965 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,03352121 0,06781513 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,03352121 0,06774077 ! defense response to virus GO:0051607 9 9 0,000 0,03352121 0,06766658 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,03352121 0,06759254 ! actin filament-based movement GO:0030048 9 9 0,000 0,03352121 0,06751867 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,03352121 0,06744496 ! regulation of protein modification process GO:0031399 79 78 1,000 0,0345963 0,06953216 ! regulation of locomotion GO:0040012 79 79 1,000 0,03541355 0,07109713 ! nuclear transport GO:0051169 79 79 1,000 0,03541355 0,07101976 GO:0006913|nucleocytoplasmic transport, ! regulation of cell motion GO:0051270 79 79 1,000 0,03541355 0,07094257 ! glycoprotein biosynthetic process GO:0009101 80 80 1,000 0,03623834 0,07251604 ! tube development GO:0035295 83 81 1,000 0,03707064 0,07410107 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,03717838 0,07423592 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,03717838 0,07415558 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,03717838 0,07407541 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,03717838 0,07399542 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,03717838 0,0739156 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,03717838 0,07383594 ! neuron maturation GO:0042551 10 10 0,000 0,03717838 0,07375647 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,03717838 0,07367716 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,03717838 0,07359802 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,03717838 0,07351905 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,03717838 0,07344025 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,03717838 0,07336162 ! hormone secretion GO:0046879 10 10 0,000 0,03717838 0,07328316 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,03717838 0,07320487 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,03717838 0,07312674 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,03717838 0,07304878 ! cAMP metabolic process GO:0046058 10 10 0,000 0,03717838 0,07297099 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,03717838 0,07289336 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,03717838 0,07281589 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,03717838 0,0727386 ! glial cell development GO:0021782 10 10 0,000 0,03717838 0,07266146 ! phototransduction GO:0007602 11 10 0,000 0,03717838 0,07258449 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,03717838 0,07250768 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,03717838 0,07243103 ! fat cell differentiation GO:0045444 10 10 0,000 0,03717838 0,07235455 ! myoblast differentiation GO:0045445 10 10 0,000 0,03717838 0,07227822 ! centrosome cycle GO:0007098 10 10 0,000 0,03717838 0,07220206 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,03717838 0,07212606 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,03717838 0,07205022 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,03717838 0,07197453 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,03717838 0,07189901 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,03717838 0,07182364 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,03717838 0,07174844 ! protein polyubiquitination GO:0000209 10 10 0,000 0,03717838 0,07167339 ! glutamate metabolic process GO:0006536 11 10 0,000 0,03717838 0,07159849 ! plasma membrane organization GO:0007009 10 10 0,000 0,03717838 0,07152375 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,03717838 0,07144917 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,03717838 0,07137475 ! lysosomal transport GO:0007041 10 10 0,000 0,03717838 0,07130048 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,03717838 0,07122636 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,03717838 0,0711524 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,03717838 0,07107859 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,03717838 0,07100493 ! exocrine system development GO:0035272 10 10 0,000 0,03717838 0,07093143 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,03717838 0,07085807 ! neuromuscular junction development GO:0007528 10 10 0,000 0,03717838 0,07078487 ! embryo implantation GO:0007566 11 10 0,000 0,03717838 0,07071182 ! regulation of protein binding GO:0043393 11 10 0,000 0,03717838 0,07063892 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,03717838 0,07056618 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,03717838 0,07049358 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,03717838 0,07042113 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,03717838 0,07034883 ! protein export from nucleus GO:0006611 10 10 0,000 0,03717838 0,07027667 ! negative regulation of immune response GO:0050777 10 10 0,000 0,03717838 0,07020467 ! cytolysis GO:0019835 10 10 0,000 0,03717838 0,07013281 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,03717838 0,0700611 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,03717838 0,06998954 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,03717838 0,06991812 ! histone deacetylation GO:0016575 10 10 0,000 0,03717838 0,06984685 ! mRNA splice site selection GO:0006376 11 10 0,000 0,03717838 0,06977572 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,03717838 0,06970474 ! gland morphogenesis GO:0022612 10 10 0,000 0,03717838 0,0696339 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,03717838 0,0695632 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,03717838 0,06949265 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,03717838 0,06942225 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,03717838 0,06935198 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,03717838 0,06928186 ! regulation of epidermis development GO:0045682 10 10 0,000 0,03717838 0,06921188 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,03717838 0,06914204 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,03717838 0,06907234 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,03717838 0,06900278 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,03717838 0,06893336 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,03717838 0,06886408 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,03717838 0,06879494 ! nerve development GO:0021675 10 10 0,000 0,03717838 0,06872593 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,03717838 0,06865707 ! gut development GO:0048565 10 10 0,000 0,03717838 0,06858835 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,03717838 0,06851976 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,03717838 0,06845131 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,03717838 0,06838299 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,03717838 0,06831481 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,03717838 0,06824677 ! protein stabilization GO:0050821 10 10 0,000 0,03717838 0,06817886 ! blood vessel morphogenesis GO:0048514 84 83 1,000 0,03875744 0,07100394 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,03961183 0,07249713 ! regulation of cellular localization GO:0060341 86 85 1,000 0,04047346 0,07400058 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,04047346 0,07392724 ! protein secretion GO:0009306 11 11 0,000 0,04082225 0,0744905 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,04082225 0,07441682 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,04082225 0,07434328 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,04082225 0,07426989 ! negative regulation of defense response GO:0031348 11 11 0,000 0,04082225 0,07419665 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,04082225 0,07412355 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,04082225 0,07405059 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,04082225 0,07397778 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,04082225 0,07390511 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,04082225 0,07383258 ! signal complex assembly GO:0007172 11 11 0,000 0,04082225 0,0737602 ! microtubule-based transport GO:0010970 11 11 0,000 0,04082225 0,07368796 ! endothelial cell migration GO:0043542 11 11 0,000 0,04082225 0,07361585 ! peroxisomal transport GO:0043574 11 11 0,000 0,04082225 0,07354389 ! protein amino acid methylation GO:0006479 11 11 0,000 0,04082225 0,07347207 GO:0008213|protein amino acid alkylation, ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,04082225 0,07340039 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,04082225 0,07332885 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,04082225 0,07325745 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,04082225 0,07318619 ! T cell proliferation GO:0042098 11 11 0,000 0,04082225 0,07311507 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,04082225 0,07304408 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,04082225 0,07297323 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,04082225 0,07290252 ! spinal cord development GO:0021510 11 11 0,000 0,04082225 0,07283195 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,04082225 0,07276151 ! smooth muscle contraction GO:0006939 11 11 0,000 0,04082225 0,07269121 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,04082225 0,07262104 ! mitotic spindle organization GO:0007052 11 11 0,000 0,04082225 0,07255101 ! fucose metabolic process GO:0006004 11 11 0,000 0,04082225 0,07248112 ! membrane budding GO:0006900 11 11 0,000 0,04082225 0,07241136 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,04082225 0,07234173 ! monoamine transport GO:0015844 11 11 0,000 0,04082225 0,07227224 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,04082225 0,07220288 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,04082225 0,07213366 ! body fluid secretion GO:0007589 11 11 0,000 0,04082225 0,07206456 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,04082225 0,0719956 ! intermediate filament-based process GO:0045103 11 11 0,000 0,04082225 0,07192677 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,04082225 0,07185807 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,04082225 0,07178951 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,04082225 0,07172107 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,04082225 0,07165276 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,04082225 0,07158459 ! oogenesis GO:0048477 11 11 0,000 0,04082225 0,07151654 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,04082225 0,07144863 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,04082225 0,07138084 ! vitamin transport GO:0051180 11 11 0,000 0,04082225 0,07131318 ! muscle maintenance GO:0046716 12 11 0,000 0,04082225 0,07124565 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,04082225 0,07117824 ! hindbrain development GO:0030902 11 11 0,000 0,04082225 0,07111097 ! steroid catabolic process GO:0006706 11 11 0,000 0,04082225 0,07104382 ! endocrine process GO:0050886 11 11 0,000 0,04082225 0,07097679 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,04082225 0,0709099 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,04082225 0,07084313 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,04082225 0,07077648 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,04082225 0,07070996 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,04082225 0,07064357 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,04445285 0,07685423 ! translational initiation GO:0006413 12 12 0,000 0,04445285 0,0767822 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,04445285 0,07671031 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,04445285 0,07663855 ! initiation of viral infection GO:0019059 12 12 0,000 0,04445285 0,07656692 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,04445285 0,07649543 ! iron ion transport GO:0006826 13 12 0,000 0,04445285 0,07642407 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,04445285 0,07635285 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,04445285 0,07628176 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,04445285 0,0762108 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,04445285 0,07613997 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,04445285 0,07606927 ! collagen metabolic process GO:0032963 12 12 0,000 0,04445285 0,07599871 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,04445285 0,07592827 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,04445285 0,07585797 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,04445285 0,0757878 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,04445285 0,07571775 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,04445285 0,07564784 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,04445285 0,07557805 GO:0042744|hydrogen peroxide catabolic process, ! actomyosin structure organization GO:0031032 12 12 0,000 0,04445285 0,07550839 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,04445285 0,07543886 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,04445285 0,07536946 ! retinoid metabolic process GO:0001523 12 12 0,000 0,04445285 0,07530019 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,04445285 0,07523104 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,04445285 0,07516202 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,04445285 0,07509313 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,04445285 0,07502436 ! acute-phase response GO:0006953 12 12 0,000 0,04445285 0,07495572 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,04445285 0,07488721 ! vacuolar transport GO:0007034 12 12 0,000 0,04445285 0,07481882 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,04445285 0,07475055 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,04445285 0,07468241 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,04445285 0,0746144 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,04445285 0,0745465 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,04445285 0,07447873 ! male gonad development GO:0008584 12 12 0,000 0,04445285 0,07441109 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,04445285 0,07434356 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,04445285 0,07427616 ! renal system process GO:0003014 12 12 0,000 0,04445285 0,07420888 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,04445285 0,07414173 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,04445285 0,07407469 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,04445285 0,07400777 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,04445285 0,07394098 ! pallium development GO:0021543 13 12 0,000 0,04445285 0,07387431 ! cell fate determination GO:0001709 12 12 0,000 0,04445285 0,07380775 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,04445285 0,07374132 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,04445285 0,07367501 ! G1 phase GO:0051318 13 12 0,000 0,04445285 0,07360881 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,04445285 0,07354273 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,04445285 0,07347678 ! detection of light stimulus GO:0009583 13 12 0,000 0,04445285 0,07341094 ! synaptogenesis GO:0007416 12 12 0,000 0,04445285 0,07334522 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,04445285 0,07327961 ! hormone transport GO:0009914 12 12 0,000 0,04445285 0,07321413 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,04445285 0,07314876 ! heme biosynthetic process GO:0006783 12 12 0,000 0,04445285 0,0730835 ! spermatid differentiation GO:0048515 13 12 0,000 0,04445285 0,07301837 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,04445285 0,07295334 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,04445285 0,07288844 ! neural tube closure GO:0001843 13 12 0,000 0,04445285 0,07282365 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,04445285 0,07275898 ! negative regulation of translation GO:0017148 12 12 0,000 0,04445285 0,07269442 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,04445285 0,07262997 ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 0,04488804 0,07327605 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,04807024 0,07840129 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,04807024 0,07833197 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,04807024 0,07826277 ! phenol metabolic process GO:0018958 13 13 0,000 0,04807024 0,07819369 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,04807024 0,07812474 ! gluconeogenesis GO:0006094 13 13 0,000 0,04807024 0,07805591 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,04807024 0,0779872 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,04807024 0,0779186 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,04807024 0,07785014 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,04807024 0,07778179 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,04807024 0,07771356 ! regeneration GO:0031099 13 13 0,000 0,04807024 0,07764545 ! keratinization GO:0031424 13 13 0,000 0,04807024 0,07757746 ! post-embryonic development GO:0009791 14 13 0,000 0,04807024 0,07750958 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,04807024 0,07744183 ! patterning of blood vessels GO:0001569 13 13 0,000 0,04807024 0,0773742 ! vasculogenesis GO:0001570 13 13 0,000 0,04807024 0,07730668 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,04807024 0,07723928 ! regulation of innate immune response GO:0045088 13 13 0,000 0,04807024 0,077172 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,04807024 0,07710483 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,04807024 0,07703779 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,04807024 0,07697085 ! autophagy GO:0006914 13 13 0,000 0,04807024 0,07690404 ! receptor metabolic process GO:0043112 14 13 0,000 0,04807024 0,07683734 ! actin filament bundle formation GO:0051017 13 13 0,000 0,04807024 0,07677076 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,04807024 0,07670429 ! ureteric bud development GO:0001657 13 13 0,000 0,04807024 0,07663794 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,04807024 0,0765717 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,04807024 0,07650557 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,04807024 0,07643956 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,04807024 0,07637367 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,04807024 0,07630788 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,04807024 0,07624222 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,04807024 0,07617666 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,04807024 0,07611121 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,04807024 0,07604588 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,04807024 0,07598066 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,04807024 0,07591556 ! vasodilation GO:0042311 14 13 0,000 0,04807024 0,07585056 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,04807024 0,07578567 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,04807024 0,0757209 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,04807024 0,07565624 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,04807024 0,07559168 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,04807024 0,07552724 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,04807024 0,07546291 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,04807024 0,07539868 ! immunoglobulin production GO:0002377 13 13 0,000 0,04807024 0,07533457 GO:0002440|production of molecular mediator of immune response, ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,04807024 0,07527056 ! cell-cell junction organization GO:0045216 13 13 0,000 0,04807024 0,07520667 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,04807024 0,07514288 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,04807024 0,0750792 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,04807024 0,07501563 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,04807024 0,07495216 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,04807024 0,0748888 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,04807024 0,07482555 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,04807024 0,07476241 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,04807024 0,07469937 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,04807024 0,07463644 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,04807024 0,07457361 ! blastocyst development GO:0001824 13 13 0,000 0,04807024 0,07451089 ! telomere organization GO:0032200 13 13 0,000 0,04807024 0,07444828 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,04807024 0,07438577 ! regulation of amine transport GO:0051952 13 13 0,000 0,04807024 0,07432337 ! tissue homeostasis GO:0001894 13 13 0,000 0,04807024 0,07426107 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,04807024 0,07419887 ! regulation of response to stress GO:0080134 97 94 1,000 0,04854377 0,07486709 ! blood vessel development GO:0001568 95 94 1,000 0,04854377 0,0748045 ! epidermis development GO:0008544 94 94 1,000 0,04854377 0,074742 ! vasculature development GO:0001944 97 96 1,000 0,05041167 0,07755318 ! neuron fate commitment GO:0048663 14 14 0,000 0,05167446 0,07942955 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,05167446 0,07936336 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,05167446 0,07929728 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,05167446 0,07923131 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,05167446 0,07916544 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,05167446 0,07909969 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,05167446 0,07903405 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,05167446 0,07896852 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,05167446 0,07890309 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,05167446 0,07883777 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,05167446 0,07877256 ! vesicle docking GO:0048278 14 14 0,000 0,05167446 0,07870746 ! superoxide metabolic process GO:0006801 15 14 0,000 0,05167446 0,07864247 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,05167446 0,07857758 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,05167446 0,0785128 ! hair cycle GO:0042633 14 14 0,000 0,05167446 0,07844813 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,05167446 0,07838356 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 0,000 0,05167446 0,0783191 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,05167446 0,07825475 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,05167446 0,0781905 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,05167446 0,07812636 ! lysosome organization GO:0007040 14 14 0,000 0,05167446 0,07806232 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,05167446 0,07799839 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,05167446 0,07793456 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,05167446 0,07787083 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,05167446 0,07780721 ! primary neural tube formation GO:0014020 15 14 0,000 0,05167446 0,0777437 ! peptide cross-linking GO:0018149 14 14 0,000 0,05167446 0,07768029 ! regulation of behavior GO:0050795 14 14 0,000 0,05167446 0,07761698 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,05167446 0,07755377 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,05167446 0,07749067 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,05167446 0,07742767 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,05167446 0,07736477 ! formation of primary germ layer GO:0001704 14 14 0,000 0,05167446 0,07730197 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,05167446 0,07723928 ! collagen fibril organization GO:0030199 14 14 0,000 0,05167446 0,07717669 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,05167446 0,07711419 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,05167446 0,0770518 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,05167446 0,07698951 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,05167446 0,07692733 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,05167446 0,07686524 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,05167446 0,07680325 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,05167446 0,07674136 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,05167446 0,07667957 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,05167446 0,07661788 ! endocytosis GO:0006897 99 98 1,000 0,05230563 0,07749139 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 1,000 0,05230563 0,07742914 ! regulation of system process GO:0044057 98 98 1,000 0,05230563 0,077367 ! anti-apoptosis GO:0006916 100 99 1,000 0,05326224 0,07871877 ! ectoderm development GO:0007398 99 99 1,000 0,05326224 0,0786557 ! muscle organ development GO:0007517 102 100 1,000 0,05422519 0,08001363 ! hemopoiesis GO:0030097 104 100 1,000 0,05422519 0,07994962 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,05526556 0,0814184 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,05526556 0,08135337 ! positive regulation of ossification GO:0045778 15 15 0,000 0,05526556 0,08128844 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,05526556 0,08122362 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,05526556 0,0811589 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,05526556 0,08109428 ! response to vitamin GO:0033273 15 15 0,000 0,05526556 0,08102977 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,05526556 0,08096536 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,05526556 0,08090105 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,05526556 0,08083684 ! ovarian follicle development GO:0001541 15 15 0,000 0,05526556 0,08077274 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,05526556 0,08070873 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,05526556 0,08064483 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,05526556 0,08058103 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,05526556 0,08051733 ! heme metabolic process GO:0042168 15 15 0,000 0,05526556 0,08045373 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,05526556 0,08039023 ! chromosome condensation GO:0030261 15 15 0,000 0,05526556 0,08032683 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,05526556 0,08026353 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,05526556 0,08020033 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,05526556 0,08013723 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,05526556 0,08007423 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,05526556 0,08001133 ! phospholipid transport GO:0015914 15 15 0,000 0,05526556 0,07994852 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,05526556 0,07988582 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,05526556 0,07982321 ! glutathione metabolic process GO:0006749 16 15 0,000 0,05526556 0,0797607 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,05526556 0,07969829 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,05526556 0,07963598 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,05526556 0,07957377 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,05526556 0,07951165 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,05526556 0,07944963 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,05526556 0,0793877 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,05526556 0,07932587 ! protein homooligomerization GO:0051260 15 15 0,000 0,05526556 0,07926414 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,05526556 0,0792025 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,05884357 0,08426473 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,05884357 0,08419931 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,05884357 0,08413399 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,05884357 0,08406877 ! learning GO:0007612 16 16 0,000 0,05884357 0,08400365 ! circadian rhythm GO:0007623 16 16 0,000 0,05884357 0,08393863 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,05884357 0,08387371 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,05884357 0,08380889 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,05884357 0,08374418 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,05884357 0,08367956 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,05884357 0,08361504 ! vesicle targeting GO:0006903 17 16 0,000 0,05884357 0,08355062 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,05884357 0,0834863 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,05884357 0,08342208 ! iron ion homeostasis GO:0055072 16 16 0,000 0,05884357 0,08335796 ! positive regulation of cell development GO:0010720 16 16 0,000 0,05884357 0,08329394 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,05884357 0,08323001 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,05884357 0,08316619 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,05884357 0,08310246 ! cell fate specification GO:0001708 16 16 0,000 0,05884357 0,08303883 ! pentose metabolic process GO:0019321 16 16 0,000 0,05884357 0,08297529 ! fatty acid transport GO:0015908 16 16 0,000 0,05884357 0,08291186 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,05884357 0,08284852 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,05884357 0,08278527 ! cofactor catabolic process GO:0051187 16 16 0,000 0,05884357 0,08272213 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,05884357 0,08265908 ! polyol metabolic process GO:0019751 16 16 0,000 0,05884357 0,08259612 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,05884357 0,08253326 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,05884357 0,0824705 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,05884357 0,08240783 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,05884357 0,08234526 GO:0001841|neural tube formation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,05884357 0,08228278 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,05884357 0,0822204 ! regulation of coagulation GO:0050818 17 16 0,000 0,05884357 0,08215811 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,06240856 0,08706963 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,06240856 0,08700377 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,06240856 0,086938 ! positive regulation of cell adhesion GO:0045785 17 17 0,000 0,06240856 0,08687234 ! myelination GO:0042552 17 17 0,000 0,06240856 0,08680678 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,06240856 0,08674131 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,06240856 0,08667594 ! leukocyte adhesion GO:0007159 17 17 0,000 0,06240856 0,08661068 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,06240856 0,08654551 ! sensory perception of smell GO:0007608 17 17 0,000 0,06240856 0,08648043 ! glucose transport GO:0015758 17 17 0,000 0,06240856 0,08641546 ! cell junction assembly GO:0034329 18 17 0,000 0,06240856 0,08635058 ! tissue remodeling GO:0048771 17 17 0,000 0,06240856 0,0862858 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,06240856 0,08622112 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,06240856 0,08615654 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,06240856 0,08609205 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,06240856 0,08602766 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,06240856 0,08596336 ! neural crest cell development GO:0014032 19 17 0,000 0,06240856 0,08589916 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,06240856 0,08583506 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,06240856 0,08577105 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,06240856 0,08570714 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,06240856 0,08564332 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,06240856 0,0855796 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,06240856 0,08551597 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,06240856 0,08545243 ! pigmentation GO:0043473 17 17 0,000 0,06240856 0,085389 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,06240856 0,08532565 ! adult locomotory behavior GO:0008344 17 17 0,000 0,06240856 0,0852624 ! embryonic organ development GO:0048568 17 17 0,000 0,06240856 0,08519924 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,06240856 0,08513618 ! liver development GO:0001889 17 17 0,000 0,06240856 0,08507321 ! gene silencing GO:0016458 17 17 0,000 0,06240856 0,08501033 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,06596056 0,08978236 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,06596056 0,0897161 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,06596056 0,08964994 ! meiosis I GO:0007127 18 18 0,000 0,06596056 0,08958387 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,06596056 0,0895179 ! membrane docking GO:0022406 18 18 0,000 0,06596056 0,08945203 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,06596056 0,08938626 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,06596056 0,08932058 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,06596056 0,089255 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,06596056 0,08918952 ! hexose transport GO:0008645 18 18 0,000 0,06596056 0,08912413 GO:0015749|monosaccharide transport, ! striated muscle contraction GO:0006941 18 18 0,000 0,06596056 0,08905884 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,06596056 0,08899364 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,06596056 0,08892854 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,06596056 0,08886353 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,06596056 0,08879862 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,06596056 0,08873381 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,06596056 0,08866908 ! ensheathment of neurons GO:0007272 18 18 0,000 0,06596056 0,08860446 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,06596056 0,08853992 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,06596056 0,08847548 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,06596056 0,08841114 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,06596056 0,08834688 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,06949962 0,09301946 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,06949962 0,09295196 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,06949962 0,09288455 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,06949962 0,09281725 ! feeding behavior GO:0007631 19 19 0,000 0,06949962 0,09275004 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,06949962 0,09268292 ! peroxisome organization GO:0007031 19 19 0,000 0,06949962 0,09261591 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,06949962 0,09254899 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,06949962 0,09248217 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,06949962 0,09241544 ! metanephros development GO:0001656 19 19 0,000 0,06949962 0,09234881 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,06949962 0,09228228 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,06949962 0,09221584 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,06949962 0,0921495 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,06949962 0,09208325 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,06949962 0,0920171 ! peripheral nervous system development GO:0007422 19 19 0,000 0,06949962 0,09195104 ! regulation of protein stability GO:0031647 19 19 0,000 0,06949962 0,09188508 ! eye morphogenesis GO:0048592 19 19 0,000 0,06949962 0,09181921 ! regulation of cell shape GO:0008360 21 19 0,000 0,06949962 0,09175344 ! placenta development GO:0001890 19 19 0,000 0,06949962 0,09168776 ! response to heat GO:0009408 19 19 0,000 0,06949962 0,09162217 ! vesicle localization GO:0051648 20 19 0,000 0,06949962 0,09155668 ! regulation of muscle development GO:0048634 21 20 0,000 0,07302578 0,09613323 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,07302578 0,09606461 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,07302578 0,09599609 ! organic ether metabolic process GO:0018904 20 20 0,000 0,07302578 0,09592767 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,07302578 0,09585934 ! neural tube development GO:0021915 21 20 0,000 0,07302578 0,09579112 ! nucleus organization GO:0006997 20 20 0,000 0,07302578 0,09572299 ! phagocytosis GO:0006909 21 20 0,000 0,07302578 0,09565495 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,07302578 0,09558702 ! protein targeting to membrane GO:0006612 22 20 0,000 0,07302578 0,09551918 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,07302578 0,09545143 ! chromatin remodeling GO:0006338 20 20 0,000 0,07302578 0,09538378 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,07302578 0,09531623 ! lipid oxidation GO:0034440 20 20 0,000 0,07302578 0,09524878 GO:0019395|fatty acid oxidation, ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,07302578 0,09518141 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,07302578 0,09511415 ! RNA modification GO:0009451 20 20 0,000 0,07302578 0,09504698 ! single fertilization GO:0007338 21 20 0,000 0,07302578 0,0949799 ! regulation of B cell activation GO:0050864 20 20 0,000 0,07302578 0,09491292 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,0765391 0,09940913 ! mRNA catabolic process GO:0006402 21 21 0,000 0,0765391 0,09933912 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 0,000 0,0765391 0,09926922 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,0765391 0,09919941 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,0765391 0,0991297 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,0765391 0,09906008 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,0765391 0,09899057 ! Notch signaling pathway GO:0007219 22 21 0,000 0,0765391 0,09892115 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,0765391 0,09885183 ! ear morphogenesis GO:0042471 21 21 0,000 0,0765391 0,0987826 ! organic anion transport GO:0015711 21 21 0,000 0,0765391 0,09871348 ! spliceosome assembly GO:0000245 22 21 0,000 0,0765391 0,09864445 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,0765391 0,09857551 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,0765391 0,09850667 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,0765391 0,09843793 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,0765391 0,09836929 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,0765391 0,09830074 ! regulation of proteolysis GO:0030162 21 21 0,000 0,0765391 0,09823228 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,0765391 0,09816392 ! RNA export from nucleus GO:0006405 22 22 0,000 0,08003961 0,10258205 ! sister chromatid segregation GO:0000819 22 22 0,000 0,08003961 0,10251077 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,08003961 0,10243958 ! regulation of ion transport GO:0043269 22 22 0,000 0,08003961 0,10236849 ! odontogenesis GO:0042476 22 22 0,000 0,08003961 0,1022975 ! cell junction organization GO:0034330 23 22 0,000 0,08003961 0,10222661 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,08003961 0,10215581 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,08003961 0,10208512 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,08003961 0,10201452 ! spindle organization GO:0007051 22 22 0,000 0,08003961 0,10194402 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,08003961 0,10187361 ! cell chemotaxis GO:0060326 23 22 0,000 0,08003961 0,10180331 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,08003961 0,1017331 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,08003961 0,10166299 ! male sex differentiation GO:0046661 22 22 0,000 0,08003961 0,10159297 ! biopolymer methylation GO:0043414 22 22 0,000 0,08003961 0,10152305 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,08003961 0,10145323 ! detection of external stimulus GO:0009581 23 22 0,000 0,08003961 0,1013835 ! neuron migration GO:0001764 22 22 0,000 0,08003961 0,10131387 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,08003961 0,10124433 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,08003961 0,10117489 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,08003961 0,10110555 ! aerobic respiration GO:0009060 22 22 0,000 0,08003961 0,1010363 ! cytokine production GO:0001816 22 22 0,000 0,08003961 0,10096714 ! cytokinesis GO:0000910 23 22 0,000 0,08003961 0,10089808 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,08003961 0,10082911 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,08352735 0,1051509 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,08352735 0,10507912 ! viral infectious cycle GO:0019058 23 23 0,000 0,08352735 0,10500744 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,08352735 0,10493586 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,08352735 0,10486438 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,08352735 0,104793 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,08352735 0,10472171 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,08352735 0,10465052 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,08352735 0,10457942 ! endocrine system development GO:0035270 23 23 0,000 0,08352735 0,10450843 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,08352735 0,10443752 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,08352735 0,10436672 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,08352735 0,10429601 ! regulation of action potential GO:0001508 24 24 0,000 0,08700238 0,10856154 ! gliogenesis GO:0042063 24 24 0,000 0,08700238 0,10848809 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,08700238 0,10841474 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,08700238 0,10834148 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,08700238 0,10826833 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,08700238 0,10819527 ! fertilization GO:0009566 25 24 0,000 0,08700238 0,10812231 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,08700238 0,10804946 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,08700238 0,1079767 ! glucan metabolic process GO:0044042 25 24 0,000 0,08700238 0,10790403 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,09046474 0,11212275 ! negative regulation of secretion GO:0051048 26 25 0,000 0,09046474 0,11204739 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,09046474 0,11197214 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,09046474 0,11189699 ! endosome transport GO:0016197 25 25 0,000 0,09046474 0,11182195 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,09046474 0,111747 ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,09046474 0,11167215 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,09046474 0,1115974 ! excretion GO:0007588 25 25 0,000 0,09046474 0,11152276 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,09046474 0,11144821 ! gastrulation GO:0007369 25 25 0,000 0,09046474 0,11137376 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,09046474 0,11129941 ! regulation of endocytosis GO:0030100 25 25 0,000 0,09046474 0,11122516 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,09046474 0,11115101 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,09046474 0,11107696 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,09046474 0,11100301 ! positive regulation of defense response GO:0031349 26 26 0,000 0,09391448 0,11515927 ! glycolysis GO:0006096 26 26 0,000 0,09391448 0,1150827 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,09391448 0,11500623 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,09391448 0,11492987 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,09391448 0,1148536 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,09391448 0,11477744 ! cellular defense response GO:0006968 26 26 0,000 0,09391448 0,11470138 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,09391448 0,11462542 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,09391448 0,11454956 ! regulation of protein secretion GO:0050708 26 26 0,000 0,09391448 0,1144738 ! germ cell development GO:0007281 27 26 0,000 0,09391448 0,11439814 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,09391448 0,11432258 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,09391448 0,11424711 ! synapse organization GO:0050808 26 26 0,000 0,09391448 0,11417175 ! chloride transport GO:0006821 27 27 0,000 0,09735163 0,11827228 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,09735163 0,11819436 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,09735163 0,11811655 ! learning or memory GO:0007611 28 27 0,000 0,09735163 0,11803885 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,09735163 0,11796124 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,09735163 0,11788374 ! peptide metabolic process GO:0006518 29 27 0,000 0,09735163 0,11780633 ! mesenchymal cell development GO:0014031 29 27 0,000 0,09735163 0,11772903 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,09735163 0,11765183 ! defense response to bacterium GO:0042742 27 27 0,000 0,09735163 0,11757474 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,09735163 0,11749774 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,10077624 0,12155144 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! neuromuscular process GO:0050905 28 28 0,000 0,10077624 0,12147194 ! carbohydrate transport GO:0008643 28 28 0,000 0,10077624 0,12139255 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,10077624 0,12131326 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,10077624 0,12123408 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,10077624 0,12115499 ! developmental growth GO:0048589 28 28 0,000 0,10077624 0,12107601 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,10077624 0,12099714 ! cartilage development GO:0051216 29 28 0,000 0,10077624 0,12091836 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,10418835 0,12493112 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,10418835 0,12484989 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,10418835 0,12476877 ! leukocyte migration GO:0050900 30 29 0,000 0,10418835 0,12468775 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,10418835 0,12460684 ! regulation of epithelial cell proliferation GO:0050678 29 29 0,000 0,10418835 0,12452603 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,10418835 0,12444532 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,10418835 0,12436472 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,10418835 0,12428423 ! tRNA processing GO:0008033 29 29 0,000 0,10418835 0,12420384 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,10418835 0,12412355 ! adult behavior GO:0030534 30 29 0,000 0,10418835 0,12404337 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,10418835 0,12396329 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,10418835 0,12388331 ! transition metal ion transport GO:0000041 31 30 0,000 0,10758802 0,12784314 ! RNA catabolic process GO:0006401 30 30 0,000 0,10758802 0,12776077 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,10758802 0,1276785 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,10758802 0,12759634 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,10758802 0,12751429 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,10758802 0,12743234 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,10758802 0,12735049 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,10758802 0,12726875 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,10758802 0,12718712 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,10758802 0,12710559 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,10758802 0,12702416 ! response to temperature stimulus GO:0009266 30 30 0,000 0,10758802 0,12694284 ! regulation of ossification GO:0030278 30 30 0,000 0,10758802 0,12686162 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,10758802 0,12678051 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,10758802 0,1266995 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,10758802 0,12661859 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,10758802 0,12653779 ! vesicle organization GO:0016050 30 30 0,000 0,10758802 0,12645709 ! establishment of organelle localization GO:0051656 31 30 0,000 0,10758802 0,12637649 ! regulation of translational initiation GO:0006446 31 31 0,000 0,11097527 0,13027225 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,11097527 0,13018933 ! membrane fusion GO:0006944 31 31 0,000 0,11097527 0,13010651 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,11097527 0,1300238 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,11097527 0,12994119 ! ion transmembrane transport GO:0034220 31 31 0,000 0,11097527 0,12985869 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,11097527 0,12977629 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,11097527 0,12969399 ! regulation of heart contraction GO:0008016 31 31 0,000 0,11097527 0,12961181 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,11097527 0,12952972 ! camera-type eye development GO:0043010 31 31 0,000 0,11097527 0,12944774 ! extracellular matrix organization GO:0030198 31 31 0,000 0,11097527 0,12936586 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,11097527 0,12928409 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,11097527 0,12920242 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,11097527 0,12912085 ! cell redox homeostasis GO:0045454 32 32 0,000 0,11435017 0,13296363 ! muscle fiber development GO:0048747 32 32 0,000 0,11435017 0,1328798 ! glucose catabolic process GO:0006007 32 32 0,000 0,11435017 0,13279607 ! lipid modification GO:0030258 32 32 0,000 0,11435017 0,13271244 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,11435017 0,13262892 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,11435017 0,13254551 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,11435017 0,1324622 ! cell maturation GO:0048469 32 32 0,000 0,11435017 0,13237899 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 0,000 0,11435017 0,13229589 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,11435017 0,1322129 ! nuclear export GO:0051168 32 32 0,000 0,11435017 0,13213001 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,11435017 0,13204722 ! kidney development GO:0001822 32 32 0,000 0,11435017 0,13196453 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,11435017 0,13188195 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,11435017 0,13179947 ! amino acid transport GO:0006865 33 33 0,000 0,11771274 0,13559036 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,11771274 0,13550567 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,11771274 0,13542109 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,11771274 0,13533661 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,11771274 0,13525223 ! regulation of actin filament length GO:0030832 34 34 0,000 0,12106303 0,13901506 ! regulation of angiogenesis GO:0045765 35 34 0,000 0,12106303 0,1389285 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,12106303 0,13884205 ! response to metal ion GO:0010038 34 34 0,000 0,12106303 0,1387557 ! ear development GO:0043583 34 34 0,000 0,12106303 0,13866947 ! muscle cell differentiation GO:0042692 35 34 0,000 0,12106303 0,13858334 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,12106303 0,13849731 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,12106303 0,1384114 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,12106303 0,13832559 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,12106303 0,13823988 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,12106303 0,13815429 ! secondary metabolic process GO:0019748 34 34 0,000 0,12106303 0,13806879 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,12106303 0,13798341 ! detection of stimulus GO:0051606 36 34 0,000 0,12106303 0,13789813 ! acute inflammatory response GO:0002526 35 35 0,000 0,12440109 0,14161286 ! regulation of cellular component size GO:0032535 35 35 0,000 0,12440109 0,14152544 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,12440109 0,14143814 ! mesoderm development GO:0007498 35 35 0,000 0,12440109 0,14135094 ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,12440109 0,14126384 ! positive regulation of phosphorylation GO:0042327 35 35 0,000 0,12440109 0,14117686 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,12440109 0,14108998 ! inorganic anion transport GO:0015698 35 35 0,000 0,12440109 0,14100321 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,12440109 0,14091654 ! regulation of immune effector process GO:0002697 35 35 0,000 0,12440109 0,14082999 ! hydrogen transport GO:0006818 36 36 0,000 0,12772696 0,14450632 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,12772696 0,14441766 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,12772696 0,14432912 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,12772696 0,14424068 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,12772696 0,14415235 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 0,000 0,12772696 0,14406413 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 0,000 0,12772696 0,14397602 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,12772696 0,14388802 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,12772696 0,14380012 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,12772696 0,14371233 ! regulation of lipase activity GO:0060191 36 36 0,000 0,12772696 0,14362465 ! activation of immune response GO:0002253 36 36 0,000 0,12772696 0,14353707 ! coagulation GO:0050817 39 36 0,000 0,12772696 0,1434496 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,13104068 0,1470816 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! meiosis GO:0007126 37 37 0,000 0,13104068 0,14699208 GO:0051327|M phase of meiotic cell cycle, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,13104068 0,14690266 ! eye development GO:0001654 37 37 0,000 0,13104068 0,14681336 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,13104068 0,14672417 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,13104068 0,14663508 ! adaptive immune response GO:0002250 37 37 0,000 0,13104068 0,1465461 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,1343423 0,15014727 ! neurotransmitter transport GO:0006836 40 38 0,000 0,1343423 0,15005627 ! exocytosis GO:0006887 40 38 0,000 0,1343423 0,14996539 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,1343423 0,14987461 ! chromosome segregation GO:0007059 38 38 0,000 0,1343423 0,14978394 ! hexose catabolic process GO:0019320 38 38 0,000 0,1343423 0,14969338 ! meiotic cell cycle GO:0051321 38 38 0,000 0,1343423 0,14960293 ! axon guidance GO:0007411 39 38 0,000 0,1343423 0,14951259 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,1343423 0,14942236 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,13763185 0,15298884 ! hemostasis GO:0007599 42 39 0,000 0,13763185 0,15289662 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,13763185 0,15280451 ! response to unfolded protein GO:0006986 39 39 0,000 0,13763185 0,15271252 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,13763185 0,15262063 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,13763185 0,15252886 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,13763185 0,1524372 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,13763185 0,15234564 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,13763185 0,1522542 ! developmental maturation GO:0021700 39 39 0,000 0,13763185 0,15216286 ! limb development GO:0060173 39 39 0,000 0,13763185 0,15207164 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,14090938 0,15559975 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,14090938 0,15550657 ! organelle localization GO:0051640 41 40 0,000 0,14090938 0,15541351 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,14417492 0,15892009 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,14417492 0,1588251 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,14417492 0,15873022 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,14417492 0,15863545 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,14417492 0,1585408 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,14417492 0,15844626 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,14417492 0,15835184 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,14742854 0,16182894 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,14742854 0,16173261 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,14742854 0,1616364 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,14742854 0,1615403 ! protein ubiquitination GO:0016567 43 42 0,000 0,14742854 0,16144432 ! response to protein stimulus GO:0051789 42 42 0,000 0,14742854 0,16134845 ! forebrain development GO:0030900 43 42 0,000 0,14742854 0,1612527 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,14742854 0,16115705 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,15067025 0,16460301 ! alcohol catabolic process GO:0046164 43 43 0,000 0,15067025 0,1645055 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,15067025 0,1644081 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,15067025 0,16431081 ! humoral immune response GO:0006959 44 44 0,000 0,15390012 0,16773383 ! mRNA transport GO:0051028 44 44 0,000 0,15390012 0,1676347 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,15390012 0,16753568 ! vitamin metabolic process GO:0006766 44 44 0,000 0,15390012 0,16743679 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,15390012 0,167338 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,15711817 0,17073631 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,15711817 0,1706357 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,15711817 0,17053521 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,15711817 0,17043483 ! protein processing GO:0016485 45 45 0,000 0,15711817 0,17033458 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,16032445 0,17370838 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,16032445 0,17360632 ! tube morphogenesis GO:0035239 47 46 0,000 0,16032445 0,17350438 ! regulation of membrane potential GO:0042391 46 46 0,000 0,16032445 0,17340256 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,163519 0,17675397 ! regulation of blood pressure GO:0008217 48 47 0,000 0,163519 0,17665036 ! amine transport GO:0015837 47 47 0,000 0,163519 0,17654687 ! calcium ion transport GO:0006816 48 48 0,000 0,16670186 0,17987795 ! actin filament organization GO:0007015 50 48 0,000 0,16670186 0,17977269 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,16670186 0,17966756 ! DNA recombination GO:0006310 48 48 0,000 0,16670186 0,17956256 ! ossification GO:0001503 50 49 0,000 0,16987308 0,18287154 GO:0060348|bone development, ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,16987308 0,18276479 ! divalent metal ion transport GO:0070838 49 49 0,000 0,16987308 0,18265816 ! response to bacterium GO:0009617 50 49 0,000 0,16987308 0,18255165 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,16987308 0,18244527 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,16987308 0,18233901 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,17303269 0,18562238 ! chromatin assembly GO:0031497 50 50 0,000 0,17303269 0,1855144 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,17303269 0,18540654 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,17303269 0,18529881 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,17303269 0,1851912 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,17303269 0,18508372 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,17618074 0,1883417 ! positive regulation of immune response GO:0050778 51 51 0,000 0,17618074 0,18823252 ! rRNA metabolic process GO:0016072 51 51 0,000 0,17618074 0,18812346 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,17618074 0,18801453 ! interphase of mitotic cell cycle GO:0051329 52 51 0,000 0,17618074 0,18790573 GO:0051325|interphase, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,17618074 0,18779705 ! protein maturation GO:0051604 51 51 0,000 0,17618074 0,18768849 ! RNA localization GO:0006403 52 52 0,000 0,17931726 0,19091953 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,17931726 0,1908093 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,17931726 0,19069919 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,17931726 0,19058922 ! sodium ion transport GO:0006814 53 53 0,000 0,18244229 0,19379893 ! tRNA metabolic process GO:0006399 53 53 0,000 0,18244229 0,1936873 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,18244229 0,19357579 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,18244229 0,19346441 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,18244229 0,19335316 ! regulation of T cell activation GO:0050863 53 53 0,000 0,18244229 0,19324204 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,18555589 0,19642705 ! response to virus GO:0009615 54 54 0,000 0,18555589 0,19631429 ! sulfur metabolic process GO:0006790 55 54 0,000 0,18555589 0,19620166 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,18555589 0,19608916 ! nucleosome organization GO:0034728 55 55 0,000 0,18865808 0,1992532 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,18865808 0,19913908 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,18865808 0,19902509 ! regulation of cell adhesion GO:0030155 56 55 0,000 0,18865808 0,19891123 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,18865808 0,1987975 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,1917489 0,20193899 ! extracellular structure organization GO:0043062 56 56 0,000 0,1917489 0,20182366 ! ATP metabolic process GO:0046034 57 57 0,000 0,1948284 0,20494792 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,1948284 0,204831 ! innate immune response GO:0045087 58 58 0,000 0,19789662 0,20793813 ! dephosphorylation GO:0016311 60 59 0,000 0,2009536 0,21102991 ! carboxylic acid transport GO:0046942 59 59 0,000 0,2009536 0,21090973 GO:0015849|organic acid transport, ! immune effector process GO:0002252 59 59 0,000 0,2009536 0,21078969 ! potassium ion transport GO:0006813 60 60 0,000 0,20399937 0,21386282 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,20399937 0,21374124 ! protein polymerization GO:0051258 65 60 0,000 0,20399937 0,2136198 ! cellular respiration GO:0045333 62 61 0,000 0,20703398 0,2166744 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,20703398 0,21655143 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,20703398 0,2164286 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,21005746 0,21946479 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,21005746 0,21934045 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 0,000 0,21005746 0,21921625 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,21005746 0,21909219 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,21005746 0,21896827 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,21005746 0,21884449 ! regulation of secretion GO:0051046 65 63 0,000 0,21306985 0,22185748 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,21306985 0,22173221 ! glucose metabolic process GO:0006006 63 63 0,000 0,21306985 0,22160708 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,21306985 0,22148209 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,21306985 0,22135724 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,2160712 0,22434886 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,2160712 0,22422254 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,2160712 0,22409635 ! positive regulation of protein metabolic process GO:0051247 64 64 0,000 0,2160712 0,22397032 ! anion transport GO:0006820 65 65 0,000 0,21906154 0,22694234 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,21906154 0,22681484 ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,22204091 0,22977058 ! DNA packaging GO:0006323 66 66 0,000 0,22204091 0,22964164 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,22204091 0,22951284 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,22204091 0,22938419 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 0,000 0,22500935 0,23232057 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 0,000 0,22500935 0,2321905 ! muscle contraction GO:0006936 67 67 0,000 0,22500935 0,23206056 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,22500935 0,23193077 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,22796689 0,23484795 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,22796689 0,23471675 ! regulation of translation GO:0006417 69 69 0,000 0,23091358 0,23761794 ! sensory perception of sound GO:0007605 71 69 0,000 0,23091358 0,23748534 GO:0050954|sensory perception of mechanical stimulus, ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,23091358 0,23735289 ! positive regulation of transport GO:0051050 71 70 0,000 0,23384946 0,24023665 ! cell part morphogenesis GO:0032990 75 70 0,000 0,23384946 0,24010281 ! wound healing GO:0042060 74 70 0,000 0,23384946 0,23996913 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,23384946 0,23983559 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,23677456 0,2427005 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,23677456 0,2425656 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,23677456 0,24243084 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,23677456 0,24229623 ! regulation of cell activation GO:0050865 71 71 0,000 0,23677456 0,24216177 ! secretion by cell GO:0032940 75 72 0,000 0,23968891 0,24500647 ! muscle system process GO:0003012 72 72 0,000 0,23968891 0,24487066 ! sensory organ development GO:0007423 72 72 0,000 0,23968891 0,244735 ! regulation of cytokine production GO:0001817 72 72 0,000 0,23968891 0,24459948 ! electron transport chain GO:0022900 75 74 0,000 0,24548556 0,25037625 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,24548556 0,25023777 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,24836793 0,25303598 ! response to oxidative stress GO:0006979 76 75 0,000 0,24836793 0,25289618 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,24836793 0,25275654 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,2512397 0,25553795 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,25410093 0,25830557 ! cell morphogenesis involved in differentiation GO:0000904 82 77 0,000 0,25410093 0,25816318 ! microtubule-based movement GO:0007018 82 78 0,000 0,25695163 0,26091563 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,25695163 0,26077195 ! metal ion homeostasis GO:0055065 78 78 0,000 0,25695163 0,26062843 ! regulation of immune response GO:0050776 78 78 0,000 0,25695163 0,26048507 ! neuron projection development GO:0031175 85 80 0,000 0,26262166 0,2660867 ! lipid catabolic process GO:0016042 82 81 0,000 0,26544105 0,26879552 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,27104876 0,27432337 ! ncRNA processing GO:0034470 83 83 0,000 0,27104876 0,27417281 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,27661529 0,27965002 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,27661529 0,2794967 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 0,000 0,27938321 0,28213877 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,27938321 0,28198426 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,27938321 0,28182992 ! male gamete generation GO:0048232 90 88 0,000 0,28488853 0,28722623 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,28488853 0,28706919 ! chemotaxis GO:0006935 90 89 0,000 0,287626 0,28966924 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,287626 0,28951104 ! brain development GO:0007420 91 90 0,000 0,29035339 0,29209678 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,29307074 0,2946696 ! DNA replication GO:0006260 91 91 0,000 0,29307074 0,29450893 ! visual perception GO:0007601 93 92 0,000 0,29577809 0,29706758 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,29577809 0,29690578 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,29577809 0,29674415 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,29577809 0,29658271 ! tissue morphogenesis GO:0048729 94 93 0,000 0,29847546 0,29912467 ! cofactor metabolic process GO:0051186 95 94 0,000 0,3011629 0,30165392 ! posttranscriptional regulation of gene expression GO:0010608 98 98 0,000 0,31181399 0,31215273 ! blood circulation GO:0008015 99 98 0,000 0,31181399 0,31198327 GO:0003013|circulatory system process, ! response to other organism GO:0051707 101 100 0,000 0,31708083 0,31708083