pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6502-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of protein export from nucleus GO:0046825 10 7 4,000 6,187E-12 1,489E-08 ! regulation of intracellular protein transport GO:0033157 80 42 6,000 6,591E-11 7,929E-08 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 6,000 1,294E-10 1,038E-07 ! phospholipid dephosphorylation GO:0046839 12 5 3,000 4,835E-10 2,908E-07 ! regulation of intracellular transport GO:0032386 101 57 6,000 6,213E-10 2,99E-07 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 1,447E-09 5,802E-07 ! organ growth GO:0035265 15 7 3,000 3,368E-09 1,158E-06 ! negative regulation of peptide secretion GO:0002792 10 7 3,000 3,368E-09 1,013E-06 GO:0046676|negative regulation of insulin secretion, ! negative regulation of focal adhesion formation GO:0051895 20 7 3,000 3,368E-09 9,003E-07 ! regulation of focal adhesion formation GO:0051893 22 8 3,000 6,719E-09 1,617E-06 ! regulation of growth hormone secretion GO:0060123 16 8 3,000 6,719E-09 1,47E-06 ! negative regulation of transport GO:0051051 153 84 6,000 9,926E-09 1,99E-06 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 3,000 1,206E-08 2,233E-06 ! regulation of protein transport GO:0051223 154 87 6,000 1,271E-08 2,184E-06 GO:0070201|regulation of establishment of protein localization, ! regulation of protein kinase B signaling cascade GO:0051896 26 10 3,000 2,006E-08 3,217E-06 ! positive regulation of MAP kinase activity GO:0043406 160 93 6,000 2,028E-08 3,05E-06 ! regulation of protein localization GO:0032880 176 97 6,000 2,722E-08 3,853E-06 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 5,000 2,849E-08 3,809E-06 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 3,000 3,144E-08 3,982E-06 GO:0010812|negative regulation of cell-substrate adhesion, ! DNA damage response, signal transduction GO:0042770 128 60 5,000 3,901E-08 4,693E-06 ! DNA damage checkpoint GO:0000077 71 33 4,000 6,549E-08 7,504E-06 ! DNA integrity checkpoint GO:0031570 75 36 4,000 1,032E-07 1,129E-05 ! androgen receptor signaling pathway GO:0030521 74 36 4,000 1,032E-07 1,08E-05 ! regulation of protein stability GO:0031647 73 37 4,000 1,191E-07 1,194E-05 ! carbohydrate homeostasis GO:0033500 53 38 4,000 1,368E-07 1,316E-05 GO:0042593|glucose homeostasis, ! negative regulation of hormone secretion GO:0046888 25 17 3,000 2,235E-07 2,068E-05 ! endothelial cell migration GO:0043542 28 17 3,000 2,235E-07 1,991E-05 ! inositol metabolic process GO:0006020 28 17 3,000 2,235E-07 1,92E-05 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 3,000 2,235E-07 1,854E-05 ! cardiac muscle tissue development GO:0048738 31 17 3,000 2,235E-07 1,792E-05 ! cellular response to hormone stimulus GO:0032870 167 82 5,000 2,579E-07 2,002E-05 ! positive regulation of hormone secretion GO:0046887 32 19 3,000 3,622E-07 2,723E-05 ! negative regulation of cell migration GO:0030336 115 46 4,000 3,661E-07 2,669E-05 ! male meiosis GO:0007140 7 6 2,000 6,234E-07 4,411E-05 ! response to UV GO:0009411 104 53 4,000 7,53E-07 5,176E-05 ! regulation of cell-matrix adhesion GO:0001952 78 23 3,000 8,193E-07 5,476E-05 GO:0010810|regulation of cell-substrate adhesion, ! negative regulation of cell motion GO:0051271 134 55 4,000 9,083E-07 5,906E-05 ! lipid modification GO:0030258 97 57 4,000 1,088E-06 6,887E-05 ! regulation of insulin secretion GO:0050796 37 25 3,000 1,165E-06 7,186E-05 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,737E-06 1,045E-04 ! steroid hormone receptor signaling pathway GO:0030518 129 63 4,000 1,799E-06 1,055E-04 ! regulation of peptide secretion GO:0002791 47 29 3,000 2,166E-06 1,241E-04 ! activation of MAPK activity GO:0000187 115 67 4,000 2,447E-06 1,369E-04 ! negative regulation of protein kinase cascade GO:0010741 68 30 3,000 2,493E-06 1,363E-04 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 4,000 2,634E-06 1,408E-04 ! cell cycle checkpoint GO:0000075 137 69 4,000 2,833E-06 1,482E-04 ! triglyceride metabolic process GO:0006641 43 31 3,000 2,855E-06 1,462E-04 ! phosphoinositide metabolic process GO:0030384 128 72 4,000 3,5E-06 1,754E-04 ! negative regulation of protein transport GO:0051224 69 33 3,000 3,695E-06 1,814E-04 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 2,000 3,706E-06 1,783E-04 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 2,000 3,706E-06 1,748E-04 ! negative regulation of secretion GO:0051048 63 35 3,000 4,705E-06 2,177E-04 ! negative regulation of cell adhesion GO:0007162 81 35 3,000 4,705E-06 2,136E-04 ! neutral lipid metabolic process GO:0006638 50 35 3,000 4,705E-06 2,096E-04 GO:0006639|acylglycerol metabolic process, ! glycerol ether metabolic process GO:0006662 53 37 3,000 5,905E-06 2,583E-04 ! organic ether metabolic process GO:0018904 55 39 3,000 7,319E-06 3,144E-04 ! regulation of hormone secretion GO:0046883 62 40 3,000 8,112E-06 3,424E-04 ! double-strand break repair via homologous recombination GO:0000724 19 13 2,000 8,771E-06 3,638E-04 GO:0000725|recombinational repair, ! response to X-ray GO:0010165 25 13 2,000 8,771E-06 3,577E-04 ! cytoplasmic sequestering of protein GO:0051220 24 13 2,000 8,771E-06 3,517E-04 ! hormone-mediated signaling GO:0009755 74 41 3,000 8,967E-06 3,537E-04 ! polyol metabolic process GO:0019751 66 41 3,000 8,967E-06 3,48E-04 ! regulation of cell adhesion GO:0030155 212 89 4,000 9,949E-06 3,8E-04 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 1,087E-05 4,088E-04 ! response to gamma radiation GO:0010332 28 14 2,000 1,114E-05 4,122E-04 ! double-strand break repair GO:0006302 81 44 3,000 1,193E-05 4,35E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 1,306E-05 4,692E-04 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 1,389E-05 4,914E-04 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 2,000 1,705E-05 5,947E-04 ! signal complex assembly GO:0007172 41 17 2,000 2,066E-05 7,101E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 2,066E-05 7,001E-04 ! regulation of multicellular organism growth GO:0040014 85 55 3,000 2,919E-05 9,753E-04 ! regulation of DNA replication GO:0006275 101 56 3,000 3,135E-05 1,033E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 3,44E-05 1,118E-03 ! positive regulation of secretion GO:0051047 95 59 3,000 3,857E-05 1,237E-03 ! cell aging GO:0007569 44 21 2,000 4,004E-05 1,268E-03 ! negative regulation of intracellular transport GO:0032387 41 21 2,000 4,004E-05 1,251E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 4,122E-05 1,272E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 4,625E-05 1,409E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 2,000 4,625E-05 1,391E-03 ! multicellular organism reproduction GO:0032504 111 64 3,000 5,319E-05 1,58E-03 GO:0048609|reproductive process in a multicellular organism, ! protein tetramerization GO:0051262 52 24 2,000 6,051E-05 1,775E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 6,86E-05 1,989E-03 ! negative regulation of DNA replication GO:0008156 42 25 2,000 6,86E-05 1,965E-03 ! regulation of transcription factor import into nucleus GO:0042990 54 26 2,000 7,737E-05 2,19E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 7,737E-05 2,165E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 8,684E-05 2,402E-03 ! meiosis GO:0007126 121 74 3,000 9,401E-05 2,57E-03 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 122 75 3,000 9,907E-05 2,678E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 9,992E-05 2,671E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 9,992E-05 2,642E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 9,992E-05 2,613E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 9,992E-05 2,585E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 9,992E-05 2,558E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 9,992E-05 2,531E-03 ! regulation of catabolic process GO:0009894 161 76 3,000 1,043E-04 2,614E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 1,08E-04 2,678E-03 ! response to ionizing radiation GO:0010212 65 32 2,000 1,456E-04 3,574E-03 ! regulation of protein import into nucleus GO:0042306 63 32 2,000 1,456E-04 3,538E-03 ! positive regulation of catabolic process GO:0009896 64 32 2,000 1,456E-04 3,502E-03 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 1,000 1,496E-04 3,563E-03 ! activation of MAPKKK activity GO:0000185 12 6 1,000 1,496E-04 3,528E-03 ! male sex determination GO:0030238 15 6 1,000 1,496E-04 3,494E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 1,496E-04 3,46E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 1,000 1,496E-04 3,427E-03 ! response to UV-C GO:0010225 11 6 1,000 1,496E-04 3,395E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 1,496E-04 3,363E-03 ! cytoplasmic microtubule organization GO:0031122 14 6 1,000 1,496E-04 3,332E-03 ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 1,908E-04 4,211E-03 ! maintenance of protein location in cell GO:0032507 86 36 2,000 2,076E-04 4,541E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 2,09E-04 4,53E-03 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 2,09E-04 4,489E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 2,09E-04 4,449E-03 ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 2,09E-04 4,41E-03 ! centrosome duplication GO:0051298 13 7 1,000 2,09E-04 4,372E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 2,09E-04 4,334E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 2,09E-04 4,297E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 2,09E-04 4,261E-03 ! response to tumor cell GO:0002347 13 7 1,000 2,09E-04 4,225E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 2,09E-04 4,19E-03 ! axonal fasciculation GO:0007413 18 7 1,000 2,09E-04 4,155E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 2,254E-04 4,445E-03 ! mammary gland development GO:0030879 86 39 2,000 2,639E-04 5,162E-03 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 2,677E-04 5,194E-03 ! hormone metabolic process GO:0042445 157 97 3,000 2,677E-04 5,153E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,78E-04 5,309E-03 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 2,78E-04 5,268E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 2,78E-04 5,226E-03 ! ER overload response GO:0006983 12 8 1,000 2,78E-04 5,186E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 2,78E-04 5,146E-03 ! blastocyst growth GO:0001832 19 8 1,000 2,78E-04 5,107E-03 ! mesenchymal cell development GO:0014031 87 40 2,000 2,847E-04 5,188E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of protein location GO:0045185 91 40 2,000 2,847E-04 5,149E-03 ! cell cycle arrest GO:0007050 213 100 3,000 3,008E-04 5,4E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 3,567E-04 6,358E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 3,567E-04 6,311E-03 ! cell proliferation in forebrain GO:0021846 15 9 1,000 3,567E-04 6,265E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 3,567E-04 6,22E-03 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 1,000 3,567E-04 6,175E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 3,567E-04 6,131E-03 ! receptor clustering GO:0043113 18 9 1,000 3,567E-04 6,087E-03 ! motor axon guidance GO:0008045 16 9 1,000 3,567E-04 6,045E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 3,567E-04 6,002E-03 ! maintenance of location in cell GO:0051651 97 44 2,000 3,781E-04 6,317E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 4,313E-04 7,157E-03 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 4,313E-04 7,108E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 4,313E-04 7,06E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 4,45E-04 7,234E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 4,45E-04 7,186E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 4,45E-04 7,138E-03 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 4,45E-04 7,091E-03 ! multicellular organism growth GO:0035264 18 10 1,000 4,45E-04 7,044E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 4,45E-04 6,998E-03 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 1,000 4,45E-04 6,953E-03 ! localization within membrane GO:0051668 20 10 1,000 4,45E-04 6,908E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 4,892E-04 7,545E-03 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 4,892E-04 7,497E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 5,428E-04 8,265E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 5,428E-04 8,213E-03 ! regulation of intracellular pH GO:0051453 19 11 1,000 5,428E-04 8,162E-03 ! positive regulation of neuron differentiation GO:0045666 19 11 1,000 5,428E-04 8,111E-03 ! oocyte differentiation GO:0009994 18 11 1,000 5,428E-04 8,061E-03 ! regulation of embryonic development GO:0045995 27 11 1,000 5,428E-04 8,012E-03 ! nucleus localization GO:0051647 19 11 1,000 5,428E-04 7,963E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 5,85E-04 8,53E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! synapse organization GO:0050808 85 52 2,000 6,193E-04 8,977E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 6,5E-04 9,364E-03 ! virus-host interaction GO:0019048 29 12 1,000 6,5E-04 9,308E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 6,5E-04 9,253E-03 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 6,5E-04 9,199E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 6,5E-04 9,145E-03 ! histone acetylation GO:0016573 26 12 1,000 6,5E-04 9,092E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 6,5E-04 9,039E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 6,5E-04 8,988E-03 GO:0042130|negative regulation of T cell proliferation, ! cell maturation GO:0048469 100 53 2,000 6,55E-04 9,005E-03 ! regulation of protein catabolic process GO:0042176 116 55 2,000 7,302E-04 9,982E-03 ! aging GO:0007568 103 55 2,000 7,302E-04 9,925E-03 ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 1,000 7,666E-04 0,01036135 ! cell-cell junction assembly GO:0007043 27 13 1,000 7,666E-04 0,01030347 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 7,666E-04 0,01024623 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 7,666E-04 0,01018962 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 7,666E-04 0,01013363 ! nucleotide-excision repair GO:0006289 83 56 2,000 7,697E-04 0,01011985 ! positive regulation of cell migration GO:0030335 126 57 2,000 8,106E-04 0,01059957 ! maintenance of location GO:0051235 118 57 2,000 8,106E-04 0,01054227 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 8,925E-04 0,01154431 ! regulation of S phase GO:0033261 23 14 1,000 8,925E-04 0,01148258 ! regulation of mRNA processing GO:0050684 24 14 1,000 8,925E-04 0,0114215 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 8,925E-04 0,01136107 ! bone mineralization GO:0030282 17 14 1,000 8,925E-04 0,01130127 ! negative regulation of protein import into nucleus GO:0042308 30 14 1,000 8,925E-04 0,0112421 ! regulation of axon extension GO:0030516 37 14 1,000 8,925E-04 0,01118355 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 8,925E-04 0,0111256 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 9,879E-04 0,01225216 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 1,028E-03 0,01267921 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,028E-03 0,01261452 ! positive regulation of cell motion GO:0051272 146 64 2,000 1,136E-03 0,0138717 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,172E-03 0,01424136 ! activation of MAPKK activity GO:0000186 35 16 1,000 1,172E-03 0,0141698 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 1,172E-03 0,01409895 ! neuron recognition GO:0008038 35 16 1,000 1,172E-03 0,01402881 ! biomineral formation GO:0031214 20 16 1,000 1,172E-03 0,01395936 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 1,172E-03 0,01389059 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,172E-03 0,0138225 ! developmental maturation GO:0021700 116 66 2,000 1,242E-03 0,01457368 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 1,297E-03 0,01514788 ! negative regulation of cell growth GO:0030308 132 67 2,000 1,297E-03 0,0150747 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 1,325E-03 0,01533238 ! negative regulation of kinase activity GO:0033673 131 68 2,000 1,354E-03 0,01558367 ! negative regulation of cell size GO:0045792 134 69 2,000 1,412E-03 0,0161772 ! neuron maturation GO:0042551 42 18 1,000 1,488E-03 0,01696842 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,488E-03 0,01688838 ! centrosome cycle GO:0007098 25 18 1,000 1,488E-03 0,01680909 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 1,488E-03 0,01673055 ! negative regulation of transferase activity GO:0051348 140 72 2,000 1,596E-03 0,01786264 ! lipid phosphorylation GO:0046834 35 19 1,000 1,66E-03 0,0184873 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 1,66E-03 0,01840211 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 1,66E-03 0,01831769 ! cerebral cortex development GO:0021987 36 19 1,000 1,66E-03 0,01823405 ! neuromuscular junction development GO:0007528 34 19 1,000 1,66E-03 0,01815117 ! cell-cell junction organization GO:0045216 35 19 1,000 1,66E-03 0,01806904 ! regulation of transcription factor activity GO:0051090 126 74 2,000 1,727E-03 0,01871689 GO:0090046|regulation of transcription regulator activity, ! cell-matrix adhesion GO:0007160 163 75 2,000 1,795E-03 0,0193648 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 1,84E-03 0,01976677 ! protein amino acid acetylation GO:0006473 39 20 1,000 1,84E-03 0,01967892 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 1,84E-03 0,01959184 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 1,84E-03 0,01950554 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 1,84E-03 0,01941999 ! cellular response to starvation GO:0009267 33 20 1,000 1,84E-03 0,01933518 ! negative regulation of T cell activation GO:0050868 40 20 1,000 1,84E-03 0,01925112 ! negative regulation of translation GO:0017148 29 20 1,000 1,84E-03 0,01916778 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 1,84E-03 0,01908516 ! protein oligomerization GO:0051259 139 78 2,000 2,008E-03 0,02073733 ! oogenesis GO:0048477 36 21 1,000 2,03E-03 0,0208705 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 2,228E-03 0,0228125 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 2,228E-03 0,02271584 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 2,228E-03 0,02261999 ! positive regulation of B cell activation GO:0050871 38 22 1,000 2,228E-03 0,02252495 ! protein stabilization GO:0050821 39 22 1,000 2,228E-03 0,0224307 ! cell-substrate adhesion GO:0031589 171 81 2,000 2,237E-03 0,02242383 ! positive regulation of DNA replication GO:0045740 43 23 1,000 2,435E-03 0,02431263 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 2,435E-03 0,02421216 ! sex determination GO:0007530 47 23 1,000 2,435E-03 0,02411252 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 2,435E-03 0,0240137 ! negative regulation of catabolic process GO:0009895 50 23 1,000 2,435E-03 0,02391569 ! negative regulation of growth GO:0045926 155 84 2,000 2,481E-03 0,02426416 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 2,651E-03 0,025825 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 2,651E-03 0,02572087 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 2,651E-03 0,02561757 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 2,651E-03 0,0255151 ! pallium development GO:0021543 49 24 1,000 2,651E-03 0,02541345 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 2,651E-03 0,0253126 ! regulation of DNA binding GO:0051101 155 88 2,000 2,831E-03 0,02692308 ! gland development GO:0048732 206 88 2,000 2,831E-03 0,02681709 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 2,876E-03 0,02713372 ! myelination GO:0042552 45 25 1,000 2,876E-03 0,02702773 ! receptor metabolic process GO:0043112 46 25 1,000 2,876E-03 0,02692256 ! response to starvation GO:0042594 42 25 1,000 2,876E-03 0,02681821 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 2,876E-03 0,02671467 ! negative regulation of cell development GO:0010721 73 25 1,000 2,876E-03 0,02661192 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 2,876E-03 0,02650996 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 2,876E-03 0,02640877 ! somitogenesis GO:0001756 43 25 1,000 2,876E-03 0,02630836 ! cellular response to nutrient levels GO:0031669 41 25 1,000 2,876E-03 0,02620871 ! ossification GO:0001503 188 90 2,000 3,017E-03 0,02739195 ! microtubule organizing center organization GO:0031023 39 26 1,000 3,109E-03 0,02812097 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 3,109E-03 0,02801565 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 3,109E-03 0,02791111 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 1,000 3,109E-03 0,02780735 ! blastocyst development GO:0001824 49 26 1,000 3,109E-03 0,02770436 ! bone development GO:0060348 189 91 2,000 3,113E-03 0,02763521 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 3,351E-03 0,02963925 ! protein amino acid acylation GO:0043543 55 27 1,000 3,351E-03 0,02953069 ! mitochondrial membrane organization GO:0007006 57 27 1,000 3,351E-03 0,02942291 ! base-excision repair GO:0006284 41 27 1,000 3,351E-03 0,02931592 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 3,351E-03 0,0292097 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 3,514E-03 0,03052336 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 3,601E-03 0,03116569 ! synaptogenesis GO:0007416 42 28 1,000 3,601E-03 0,03105399 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 3,601E-03 0,03094308 ! interphase GO:0051325 213 98 2,000 3,835E-03 0,03283648 ! regulation of pH GO:0006885 43 29 1,000 3,86E-03 0,0329312 ! response to organic cyclic substance GO:0014070 55 29 1,000 3,86E-03 0,03281484 ! tissue homeostasis GO:0001894 48 29 1,000 3,86E-03 0,03269929 GO:0048871|multicellular organismal homeostasis, ! skeletal muscle tissue development GO:0007519 186 99 2,000 3,946E-03 0,033311 GO:0060538|skeletal muscle organ development, ! cell junction assembly GO:0034329 78 30 1,000 4,127E-03 0,03471803 ! ensheathment of neurons GO:0007272 57 30 1,000 4,127E-03 0,03459706 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 4,127E-03 0,03447693 ! regulation of B cell activation GO:0050864 50 30 1,000 4,127E-03 0,03435763 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 4,402E-03 0,03652482 GO:0043433|negative regulation of transcription factor activity, ! spindle organization GO:0007051 46 32 1,000 4,686E-03 0,03874569 ! regulation of axonogenesis GO:0050770 75 32 1,000 4,686E-03 0,038613 ! peripheral nervous system development GO:0007422 64 32 1,000 4,686E-03 0,03848122 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 4,978E-03 0,0407402 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 5,278E-03 0,04305062 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 5,587E-03 0,04541152 ! female gonad development GO:0008585 58 35 1,000 5,587E-03 0,04525862 ! telencephalon development GO:0021537 68 35 1,000 5,587E-03 0,04510674 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 5,587E-03 0,04495588 ! calcium-mediated signaling GO:0019722 62 35 1,000 5,587E-03 0,04480603 ! regulation of microtubule-based process GO:0032886 78 35 1,000 5,587E-03 0,04465717 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 5,903E-03 0,0470302 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! cell junction organization GO:0034330 86 36 1,000 5,903E-03 0,04687498 ! negative regulation of cell activation GO:0050866 65 36 1,000 5,903E-03 0,04672079 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 6,228E-03 0,049127 ! negative regulation of DNA binding GO:0043392 68 37 1,000 6,228E-03 0,04896646 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 6,56E-03 0,05141214 ! regulation of neuron projection development GO:0010975 91 38 1,000 6,56E-03 0,05124522 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 6,56E-03 0,05107938 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 6,56E-03 0,0509146 GO:0046660|female sex differentiation, ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 6,56E-03 0,05075089 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 6,56E-03 0,05058823 ! learning GO:0007612 77 39 1,000 6,9E-03 0,05304271 ! segmentation GO:0035282 67 39 1,000 6,9E-03 0,05287378 ! regulation of action potential in neuron GO:0019228 73 39 1,000 6,9E-03 0,05270593 ! negative regulation of binding GO:0051100 72 40 1,000 7,249E-03 0,05519029 ! cytokinesis GO:0000910 72 40 1,000 7,249E-03 0,05501619 ! regulation of T cell proliferation GO:0042129 71 41 1,000 7,605E-03 0,05753676 ! T cell differentiation GO:0030217 81 41 1,000 7,605E-03 0,0573564 ! regulation of T cell differentiation GO:0045580 70 41 1,000 7,605E-03 0,05717716 ! female gamete generation GO:0007292 61 41 1,000 7,605E-03 0,05699904 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 7,968E-03 0,05954012 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 7,968E-03 0,05935579 ! neuron migration GO:0001764 79 42 1,000 7,968E-03 0,05917259 ! B cell differentiation GO:0030183 107 44 1,000 8,719E-03 0,06454734 ! developmental growth GO:0048589 82 44 1,000 8,719E-03 0,06434934 ! cell growth GO:0016049 84 45 1,000 9,106E-03 0,06699809 ! positive regulation of protein transport GO:0051222 72 46 1,000 9,5E-03 0,06968609 ! endosome transport GO:0016197 108 47 1,000 9,902E-03 0,07241262 ! positive regulation of DNA binding GO:0043388 73 47 1,000 9,902E-03 0,07219319 ! mitochondrial transport GO:0006839 82 48 1,000 0,01031105 0,07494983 ! activation of caspase activity GO:0006919 84 48 1,000 0,01031105 0,07472407 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,01031105 0,07449968 ! regulation of action potential GO:0001508 95 49 1,000 0,0107277 0,07727796 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,0107277 0,07704728 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,01115169 0,07985408 ! histone modification GO:0016570 91 50 1,000 0,01115169 0,07961712 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,01115169 0,07938157 ! positive regulation of binding GO:0051099 78 51 1,000 0,01158299 0,08220846 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,01158299 0,08196667 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,01202153 0,08482055 ! positive regulation of growth GO:0045927 90 52 1,000 0,01202153 0,08457254 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01202153 0,08432597 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,01246728 0,08719847 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,01292018 0,0901042 GO:0010863|positive regulation of phospholipase C activity, ! cell recognition GO:0008037 85 54 1,000 0,01292018 0,08984378 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,01338018 0,09277438 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,01338018 0,09250779 ! heart morphogenesis GO:0003007 97 55 1,000 0,01338018 0,09224272 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,01384723 0,09518984 ! muscle fiber development GO:0048747 112 57 1,000 0,01432129 0,09816817 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,01432129 0,09788929 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,01480231 0,10089052 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,0158376 0,10764203 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,0158376 0,10733881 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,0158376 0,1070373 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,0158376 0,10673747 ! neuron fate determination GO:0048664 7 5 0,000 0,0158376 0,10643932 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0158376 0,10614283 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,0158376 0,10584799 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,0158376 0,10555479 ! polyol transport GO:0015791 12 5 0,000 0,0158376 0,1052632 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,0158376 0,10497322 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,0158376 0,10468483 ! response to superoxide GO:0000303 10 5 0,000 0,0158376 0,10439802 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,0158376 0,10411278 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,0158376 0,10382909 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,0158376 0,10354695 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,0158376 0,10326633 ! female meiosis GO:0007143 7 5 0,000 0,0158376 0,10298724 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,0158376 0,10270964 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,0158376 0,10243354 ! cobalt ion transport GO:0006824 11 5 0,000 0,0158376 0,10215892 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,0158376 0,10188577 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,0158376 0,10161407 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,0158376 0,10134382 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,0158376 0,10107501 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,0158376 0,10080761 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,0158376 0,10054163 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,0158376 0,10027705 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,0158376 0,10001385 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,0158376 0,09975204 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0158376 0,09949159 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,0158376 0,09923249 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,0158376 0,09897475 ! negative chemotaxis GO:0050919 14 5 0,000 0,0158376 0,09871834 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,0158376 0,09846325 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,0158376 0,09820948 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,0158376 0,09795701 ! behavioral response to pain GO:0048266 9 5 0,000 0,0158376 0,09770584 ! clathrin coat assembly GO:0048268 14 5 0,000 0,0158376 0,09745595 ! Notch receptor processing GO:0007220 8 5 0,000 0,0158376 0,09720734 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0158376 0,09695999 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,0158376 0,0967139 ! micturition GO:0060073 9 5 0,000 0,0158376 0,09646906 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,0158376 0,09622545 ! copulation GO:0007620 9 5 0,000 0,0158376 0,09598307 ! glial cell fate commitment GO:0021781 13 5 0,000 0,0158376 0,0957419 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,0158376 0,09550195 ! spermidine metabolic process GO:0008216 7 5 0,000 0,0158376 0,09526319 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,0158376 0,09502563 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,0158376 0,09478925 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,0158376 0,09455404 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,0158376 0,09431999 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,0158376 0,0940871 ! grooming behavior GO:0007625 6 5 0,000 0,0158376 0,09385536 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,0158376 0,09362476 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,0158376 0,09339529 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0158376 0,09316694 ! response to protozoan GO:0001562 10 5 0,000 0,0158376 0,0929397 ! lymph vessel development GO:0001945 10 5 0,000 0,0158376 0,09271357 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,0158376 0,09248854 ! endochondral ossification GO:0001958 16 5 0,000 0,0158376 0,09226459 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,0158376 0,09204173 ! parathyroid gland development GO:0060017 13 5 0,000 0,0158376 0,09181995 ! anagen GO:0042640 6 5 0,000 0,0158376 0,09159922 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,0158376 0,09137956 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,0158376 0,09116095 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,0158376 0,09094338 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,0158376 0,09072685 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,0158376 0,09051135 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,0158376 0,09029687 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,0158376 0,0900834 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,0158376 0,08987094 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,0158376 0,08965948 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,0158376 0,08944901 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,0158376 0,08923953 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,0158376 0,08903102 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,0158376 0,08882349 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,0158376 0,08861692 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,0158376 0,08841132 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,0158376 0,08820666 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,0158376 0,08800295 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,0158376 0,08780018 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,0158376 0,08759834 ! histidine catabolic process GO:0006548 6 5 0,000 0,0158376 0,08739743 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,0158376 0,08719743 ! microvillus organization GO:0032528 7 5 0,000 0,0158376 0,08699835 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,0158376 0,08680018 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,0158376 0,0866029 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,0158376 0,08640652 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,0158376 0,08621103 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,0158376 0,08601643 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,0158376 0,0858227 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,0158376 0,08562984 ! polyol catabolic process GO:0046174 7 5 0,000 0,0158376 0,08543784 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,0158376 0,08524671 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,0158376 0,08505642 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,0158376 0,08486699 ! muscle cell migration GO:0014812 8 5 0,000 0,0158376 0,08467839 ! mitochondrial fission GO:0000266 8 5 0,000 0,0158376 0,08449064 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,0158376 0,08430371 ! mRNA transcription GO:0009299 9 5 0,000 0,0158376 0,08411761 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,0158376 0,08393233 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,0158376 0,08374786 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,0158376 0,0835642 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,0158376 0,08338135 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,0158376 0,0831993 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,0158376 0,08301803 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,0158376 0,08283756 ! response to food GO:0032094 6 5 0,000 0,0158376 0,08265787 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,0158376 0,08247896 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,0158376 0,08230082 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,0158376 0,08212344 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0158376 0,08194683 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,0158376 0,08177098 ! forebrain neuron development GO:0021884 13 5 0,000 0,0158376 0,08159588 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,0158376 0,08142153 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,0158376 0,08124793 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,0158376 0,08107506 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0158376 0,08090292 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,0158376 0,08073152 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,0158376 0,08056084 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0158376 0,08039088 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,0158376 0,08022164 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,0158376 0,0800531 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,0158376 0,07988528 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,0158376 0,07971815 ! basic amino acid transport GO:0015802 11 5 0,000 0,0158376 0,07955173 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0158376 0,07938599 ! depyrimidination GO:0045008 10 5 0,000 0,0158376 0,07922095 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,0158376 0,07905659 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,0158376 0,07889291 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,0158376 0,07872991 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,0158376 0,07856758 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,0158376 0,07840592 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,0158376 0,07824492 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0158376 0,07808458 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,0158376 0,0779249 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,0158376 0,07776587 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,0158376 0,07760749 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,0158376 0,07744975 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,0158376 0,07729265 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0158376 0,07713619 ! response to arsenic GO:0046685 10 5 0,000 0,0158376 0,07698036 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,0158376 0,07682516 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,0158376 0,07667058 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,0158376 0,07651662 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,0158376 0,07636328 ! response to cadmium ion GO:0046686 7 5 0,000 0,0158376 0,07621055 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,0158376 0,07605844 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,0158376 0,07590693 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,0158376 0,07575602 ! decidualization GO:0046697 11 5 0,000 0,0158376 0,07560571 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,0158376 0,07545599 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,0158376 0,07530687 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,0158376 0,07515834 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,0158376 0,07501039 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,0158376 0,07486302 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,0158376 0,07471623 ! neural tube patterning GO:0021532 7 5 0,000 0,0158376 0,07457001 ! embryonic cleavage GO:0040016 6 5 0,000 0,0158376 0,07442437 ! peroxisome fission GO:0016559 5 5 0,000 0,0158376 0,07427929 ! histone demethylation GO:0016577 10 5 0,000 0,0158376 0,07413478 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,0158376 0,07399083 ! mitotic recombination GO:0006312 9 5 0,000 0,0158376 0,07384744 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,0158376 0,0737046 ! metaphase plate congression GO:0051310 7 5 0,000 0,0158376 0,07356231 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0158376 0,07342057 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,0158376 0,07327938 ! enteric nervous system development GO:0048484 8 5 0,000 0,0158376 0,07313873 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,0158376 0,07299862 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,0158376 0,07285904 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,0158376 0,07272 ! muscle cell proliferation GO:0033002 11 5 0,000 0,0158376 0,07258148 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,0158376 0,07244349 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,0158376 0,07230603 ! plasminogen activation GO:0031639 5 5 0,000 0,0158376 0,07216909 ! B cell homeostasis GO:0001782 13 5 0,000 0,0158376 0,07203266 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,0158376 0,07189675 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,0158376 0,07176135 ! metaphase GO:0051323 8 5 0,000 0,0158376 0,07162646 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,0158376 0,07149208 ! cellular response to nutrient GO:0031670 8 5 0,000 0,0158376 0,0713582 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,0158376 0,07122482 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,0158376 0,07109194 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,0158376 0,07095955 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,0158376 0,07082765 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,0158376 0,07069625 ! response to redox state GO:0051775 5 5 0,000 0,0158376 0,07056533 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,0158376 0,07043489 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,0158376 0,07030494 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,0158376 0,07017546 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,0158376 0,07004647 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0158376 0,06991794 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,0158376 0,06978989 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0158376 0,0696623 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,0158376 0,06953518 ! striatum development GO:0021756 9 5 0,000 0,0158376 0,06940852 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,0158376 0,06928232 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,0158376 0,06915658 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,0158376 0,0690313 ! glial cell migration GO:0008347 11 5 0,000 0,0158376 0,06890647 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,0158376 0,06878209 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,0158376 0,06865816 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,0158376 0,06853467 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,0158376 0,06841163 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,0158376 0,06828903 ! neuroprotection GO:0043526 6 5 0,000 0,0158376 0,06816686 ! neural plate development GO:0001840 8 5 0,000 0,0158376 0,06804514 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,0158376 0,06792385 ! regulation of sensory perception GO:0051931 7 5 0,000 0,0158376 0,06780298 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,0158376 0,06768255 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,0158376 0,06756255 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,0158376 0,06744297 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,0158376 0,06732381 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,0158376 0,06720507 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,0158376 0,06708676 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,0158376 0,06696885 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,0158376 0,06685136 ! spindle assembly GO:0051225 6 5 0,000 0,0158376 0,06673429 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,0158376 0,06661762 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,0158376 0,06650136 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,0158376 0,0663855 ! drug metabolic process GO:0017144 6 5 0,000 0,0158376 0,06627005 ! stem cell division GO:0017145 11 5 0,000 0,0158376 0,066155 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,0158376 0,06604034 ! organ regeneration GO:0031100 7 5 0,000 0,0158376 0,06592609 ! carnitine metabolic process GO:0009437 7 5 0,000 0,0158376 0,06581222 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,0158376 0,06569875 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,0158376 0,06558568 ! viral reproductive process GO:0022415 126 62 1,000 0,01679497 0,06943077 ! gonad development GO:0008406 98 62 1,000 0,01679497 0,06931168 ! germ cell development GO:0007281 118 65 1,000 0,01836018 0,07564142 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,01889513 0,07771228 ! actin filament organization GO:0007015 148 66 1,000 0,01889513 0,07757966 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01897521 0,07777574 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01897521 0,07764346 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01897521 0,07751164 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01897521 0,07738027 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01897521 0,07724934 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01897521 0,07711885 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01897521 0,0769888 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01897521 0,07685919 ! sleep GO:0030431 13 6 0,000 0,01897521 0,07673001 ! response to oxygen radical GO:0000305 11 6 0,000 0,01897521 0,07660127 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01897521 0,07647296 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01897521 0,07634508 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01897521 0,07621762 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01897521 0,0760906 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01897521 0,07596399 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01897521 0,0758378 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01897521 0,07571204 ! forebrain regionalization GO:0021871 8 6 0,000 0,01897521 0,07558668 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01897521 0,07546175 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01897521 0,07533722 ! response to zinc ion GO:0010043 9 6 0,000 0,01897521 0,07521311 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01897521 0,0750894 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01897521 0,0749661 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01897521 0,07484321 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01897521 0,07472072 ! malate metabolic process GO:0006108 11 6 0,000 0,01897521 0,07459862 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01897521 0,07447693 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01897521 0,07435563 ! protein refolding GO:0042026 15 6 0,000 0,01897521 0,07423473 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01897521 0,07411422 ! opsonization GO:0008228 8 6 0,000 0,01897521 0,0739941 ! mating behavior GO:0007617 7 6 0,000 0,01897521 0,07387436 ! neuron remodeling GO:0016322 15 6 0,000 0,01897521 0,07375502 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01897521 0,07363606 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01897521 0,07351748 ! equilibrioception GO:0050957 14 6 0,000 0,01897521 0,07339929 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01897521 0,07328147 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01897521 0,07316403 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01897521 0,07304697 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01897521 0,07293028 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01897521 0,07281397 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01897521 0,07269802 ! toxin metabolic process GO:0009404 11 6 0,000 0,01897521 0,07258244 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01897521 0,07246723 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01897521 0,07235239 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01897521 0,07223791 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01897521 0,07212379 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01897521 0,07201003 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01897521 0,07189663 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01897521 0,07178358 ! thymic T cell selection GO:0045061 12 6 0,000 0,01897521 0,07167089 ! protein lipoylation GO:0009249 10 6 0,000 0,01897521 0,07155855 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01897521 0,07144657 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01897521 0,07133493 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01897521 0,07122365 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01897521 0,07111271 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01897521 0,07100211 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01897521 0,07089186 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01897521 0,07078195 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01897521 0,07067238 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01897521 0,07056315 ! hyperosmotic response GO:0006972 9 6 0,000 0,01897521 0,07045426 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01897521 0,0703457 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01897521 0,07023747 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01897521 0,07012958 ! urea metabolic process GO:0019627 7 6 0,000 0,01897521 0,07002202 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01897521 0,06991479 ! neutrophil activation GO:0042119 8 6 0,000 0,01897521 0,06980789 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01897521 0,06970131 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01897521 0,06959506 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01897521 0,06948913 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01897521 0,06938352 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01897521 0,06927824 ! neuron apoptosis GO:0051402 9 6 0,000 0,01897521 0,06917327 ! nucleoside salvage GO:0043174 9 6 0,000 0,01897521 0,06906862 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01897521 0,06896429 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01897521 0,06886027 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01897521 0,06875656 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01897521 0,06865317 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01897521 0,06855009 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01897521 0,06844731 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01897521 0,06834485 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01897521 0,06824269 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01897521 0,06814083 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01897521 0,06803928 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01897521 0,06793803 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01897521 0,06783708 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01897521 0,06773644 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01897521 0,06763608 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01897521 0,06753603 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01897521 0,06743627 ! neural nucleus development GO:0048857 14 6 0,000 0,01897521 0,06733681 ! astrocyte development GO:0014002 15 6 0,000 0,01897521 0,06723764 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01897521 0,06713876 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01897521 0,06704017 ! interaction with symbiont GO:0051702 13 6 0,000 0,01897521 0,06694187 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01897521 0,06684386 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01897521 0,06674614 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01897521 0,0666487 ! response to copper ion GO:0046688 10 6 0,000 0,01897521 0,06655154 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01897521 0,06645467 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01897521 0,06635808 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01897521 0,06626177 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01897521 0,06616574 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01897521 0,06606998 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01897521 0,0659745 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01897521 0,0658793 ! hair follicle maturation GO:0048820 7 6 0,000 0,01897521 0,06578438 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01897521 0,06568972 ! Schwann cell development GO:0014044 15 6 0,000 0,01897521 0,06559534 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01897521 0,06550123 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01897521 0,06540739 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01897521 0,06531382 ! subpallium development GO:0021544 10 6 0,000 0,01897521 0,06522051 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01897521 0,06512747 ! histone ubiquitination GO:0016574 8 6 0,000 0,01897521 0,0650347 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01897521 0,06494219 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01897521 0,06484994 ! G2 phase GO:0051319 16 6 0,000 0,01897521 0,06475795 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01897521 0,06466623 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01897521 0,06457476 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01897521 0,06448356 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01897521 0,06439261 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01897521 0,06430191 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01897521 0,06421147 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01897521 0,06412129 ! receptor internalization GO:0031623 10 6 0,000 0,01897521 0,06403136 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01897521 0,06394168 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01897521 0,06385225 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01897521 0,06376307 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01897521 0,06367414 ! protein deubiquitination GO:0016579 14 6 0,000 0,01897521 0,06358546 ! protein destabilization GO:0031648 9 6 0,000 0,01897521 0,06349702 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01897521 0,06340883 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01897521 0,06332088 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01897521 0,06323318 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01897521 0,06314572 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01897521 0,0630585 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01897521 0,06297153 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01897521 0,06288479 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01897521 0,06279829 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01897521 0,06271203 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01897521 0,062626 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01897521 0,06254022 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01897521 0,06245466 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01897521 0,06236934 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01897521 0,06228425 ! catecholamine transport GO:0051937 9 6 0,000 0,01897521 0,0621994 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01897521 0,06211477 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01897521 0,06203038 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01897521 0,06194621 ! maternal placenta development GO:0001893 12 6 0,000 0,01897521 0,06186227 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01897521 0,06177856 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01897521 0,06169508 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01897521 0,06161182 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01897521 0,06152878 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01897521 0,06144597 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01897521 0,06136338 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01897521 0,06128102 ! lung development GO:0030324 144 67 1,000 0,01943661 0,06268698 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,01943661 0,06260306 ! viral reproduction GO:0016032 134 68 1,000 0,01998458 0,06428195 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01998458 0,06419613 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,02053899 0,06588907 ! respiratory tube development GO:0030323 150 70 1,000 0,02109978 0,06759798 ! reproductive structure development GO:0048608 113 71 1,000 0,02166693 0,06932266 ! B cell activation GO:0042113 160 71 1,000 0,02166693 0,06923059 ! tRNA transcription GO:0009304 14 7 0,000 0,02210292 0,07053 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02210292 0,07043658 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02210292 0,07034341 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02210292 0,07025049 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02210292 0,07015781 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02210292 0,07006538 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02210292 0,06997318 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02210292 0,06988124 ! prostate gland development GO:0030850 13 7 0,000 0,02210292 0,06978953 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02210292 0,06969806 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02210292 0,06960683 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02210292 0,06951584 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02210292 0,06942509 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02210292 0,06933458 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02210292 0,0692443 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02210292 0,06915425 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,02210292 0,06906444 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02210292 0,06897486 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02210292 0,06888552 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02210292 0,0687964 ! glycolipid transport GO:0046836 10 7 0,000 0,02210292 0,06870752 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02210292 0,06861886 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,02210292 0,06853044 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02210292 0,06844224 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02210292 0,06835427 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02210292 0,06826652 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02210292 0,068179 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02210292 0,0680917 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02210292 0,06800463 ! mRNA stabilization GO:0048255 18 7 0,000 0,02210292 0,06791778 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02210292 0,06783115 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02210292 0,06774474 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02210292 0,06765855 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02210292 0,06757258 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02210292 0,06748683 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02210292 0,06740129 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02210292 0,06731597 ! lipoprotein transport GO:0042953 14 7 0,000 0,02210292 0,06723087 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02210292 0,06714598 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02210292 0,06706131 ! rhythmic behavior GO:0007622 15 7 0,000 0,02210292 0,06697685 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02210292 0,0668926 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02210292 0,06680857 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02210292 0,06672474 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02210292 0,06664113 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02210292 0,06655772 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02210292 0,06647452 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02210292 0,06639154 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02210292 0,06630875 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02210292 0,06622618 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02210292 0,06614381 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02210292 0,06606164 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02210292 0,06597968 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02210292 0,06589792 ! spinal cord patterning GO:0021511 13 7 0,000 0,02210292 0,06581636 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02210292 0,06573501 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02210292 0,06565385 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02210292 0,0655729 ! adrenal gland development GO:0030325 17 7 0,000 0,02210292 0,06549214 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02210292 0,06541159 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02210292 0,06533123 ! ovulation GO:0030728 9 7 0,000 0,02210292 0,06525107 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02210292 0,0651711 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02210292 0,06509133 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02210292 0,06501176 ! microtubule nucleation GO:0007020 20 7 0,000 0,02210292 0,06493238 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02210292 0,06485319 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02210292 0,0647742 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02210292 0,0646954 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02210292 0,06461679 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02210292 0,06453837 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02210292 0,06446015 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02210292 0,06438211 ! galactose metabolic process GO:0006012 13 7 0,000 0,02210292 0,06430426 ! vesicle fusion GO:0006906 17 7 0,000 0,02210292 0,06422659 ! response to dietary excess GO:0002021 8 7 0,000 0,02210292 0,06414912 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02210292 0,06407183 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02210292 0,06399473 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02210292 0,06391781 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02210292 0,06384108 ! purine salvage GO:0043101 10 7 0,000 0,02210292 0,06376453 ! nucleoside transport GO:0015858 8 7 0,000 0,02210292 0,06368817 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02210292 0,06361199 ! parturition GO:0007567 14 7 0,000 0,02210292 0,06353599 ! rRNA modification GO:0000154 14 7 0,000 0,02210292 0,06346017 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02210292 0,06338453 ! spindle checkpoint GO:0031577 15 7 0,000 0,02210292 0,06330907 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,02210292 0,06323379 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02210292 0,06315869 ! macrophage differentiation GO:0030225 11 7 0,000 0,02210292 0,06308377 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02210292 0,06300903 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02210292 0,06293446 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02210292 0,06286007 ! fibrinolysis GO:0042730 10 7 0,000 0,02210292 0,06278586 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02210292 0,06271182 ! eating behavior GO:0042755 7 7 0,000 0,02210292 0,06263795 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02210292 0,06256426 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02210292 0,06249074 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02210292 0,06241739 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02210292 0,06234422 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02210292 0,06227122 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02210292 0,06219839 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02210292 0,06212572 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02210292 0,06205323 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02210292 0,06198091 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02210292 0,06190875 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02210292 0,06183677 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02210292 0,06176495 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02210292 0,06169329 ! regulation of meiosis GO:0040020 12 7 0,000 0,02210292 0,06162181 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02210292 0,06155049 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02210292 0,06147933 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02210292 0,06140834 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02210292 0,06133751 ! transcription termination GO:0006353 13 7 0,000 0,02210292 0,06126684 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02210292 0,06119634 ! anaphase GO:0051322 17 7 0,000 0,02210292 0,061126 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02210292 0,06105582 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02210292 0,0609858 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02210292 0,06091594 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02210292 0,06084625 ! diuresis GO:0030146 12 7 0,000 0,02210292 0,06077671 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02210292 0,06070733 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02210292 0,06063811 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02210292 0,06056904 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02210292 0,06050014 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02210292 0,06043139 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02210292 0,06036279 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02210292 0,06029435 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02210292 0,06022607 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02210292 0,06015794 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02210292 0,06008997 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02210292 0,06002214 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02210292 0,05995448 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02210292 0,05988696 ! lymph node development GO:0048535 10 7 0,000 0,02210292 0,05981959 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02210292 0,05975238 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02210292 0,05968532 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02210292 0,05961841 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02210292 0,05955165 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02210292 0,05948503 ! adult feeding behavior GO:0008343 9 7 0,000 0,02210292 0,05941857 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02210292 0,05935225 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02210292 0,05928609 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02210292 0,05922007 ! muscle adaptation GO:0043500 14 7 0,000 0,02210292 0,05915419 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02210292 0,05908847 ! retina homeostasis GO:0001895 12 7 0,000 0,02210292 0,05902289 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02210292 0,05895745 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02210292 0,05889216 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02210292 0,05882701 ! protein prenylation GO:0018342 18 7 0,000 0,02210292 0,05876201 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02210292 0,05869715 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02210292 0,05863244 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02210292 0,05856786 ! regulation of caspase activity GO:0043281 122 72 1,000 0,02224038 0,05886728 ! respiratory system development GO:0060541 153 72 1,000 0,02224038 0,05880259 ! learning or memory GO:0007611 147 73 1,000 0,02282009 0,06026908 ! axon guidance GO:0007411 139 73 1,000 0,02282009 0,06020299 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,02340601 0,06168111 ! organelle localization GO:0051640 136 74 1,000 0,02340601 0,06161362 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,02399809 0,06310319 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,02399809 0,0630343 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,0245963 0,06453512 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,02520059 0,06604862 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02522076 0,06602953 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02522076 0,06595776 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02522076 0,06588614 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02522076 0,06581468 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02522076 0,06574338 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02522076 0,06567223 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02522076 0,06560123 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02522076 0,06553039 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02522076 0,0654597 ! meiotic prophase I GO:0007128 13 8 0,000 0,02522076 0,06538916 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02522076 0,06531877 ! oligopeptide transport GO:0006857 15 8 0,000 0,02522076 0,06524854 ! UTP metabolic process GO:0046051 8 8 0,000 0,02522076 0,06517845 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02522076 0,06510852 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02522076 0,06503873 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02522076 0,0649691 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02522076 0,06489961 ! succinate metabolic process GO:0006105 14 8 0,000 0,02522076 0,06483028 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02522076 0,06476109 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02522076 0,06469205 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02522076 0,06462315 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02522076 0,0645544 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02522076 0,0644858 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02522076 0,06441735 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02522076 0,06434903 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02522076 0,06428087 ! reflex GO:0060004 16 8 0,000 0,02522076 0,06421285 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02522076 0,06414497 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02522076 0,06407723 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02522076 0,06400964 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02522076 0,06394219 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02522076 0,06387488 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02522076 0,06380772 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02522076 0,06374069 ! pigment granule organization GO:0048753 16 8 0,000 0,02522076 0,06367381 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02522076 0,06360706 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02522076 0,06354046 ! histidine metabolic process GO:0006547 16 8 0,000 0,02522076 0,063474 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02522076 0,06340767 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02522076 0,06334148 ! glycine catabolic process GO:0006546 13 8 0,000 0,02522076 0,06327543 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02522076 0,06320952 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02522076 0,06314375 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02522076 0,06307811 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02522076 0,06301261 ! melanin metabolic process GO:0006582 15 8 0,000 0,02522076 0,06294724 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02522076 0,06288201 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02522076 0,06281691 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02522076 0,06275195 ! macrophage activation GO:0042116 12 8 0,000 0,02522076 0,06268713 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02522076 0,06262244 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02522076 0,06255788 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02522076 0,06249345 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02522076 0,06242916 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02522076 0,06236499 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02522076 0,06230096 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02522076 0,06223707 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02522076 0,0621733 ! osteoblast development GO:0002076 16 8 0,000 0,02522076 0,06210966 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02522076 0,06204615 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02522076 0,06198278 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02522076 0,06191953 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02522076 0,06185641 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02522076 0,06179342 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02522076 0,06173056 ! response to UV-B GO:0010224 16 8 0,000 0,02522076 0,06166782 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02522076 0,06160522 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02522076 0,06154274 ! intermediate filament organization GO:0045109 12 8 0,000 0,02522076 0,06148038 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02522076 0,06141816 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02522076 0,06135606 ! cellular extravasation GO:0045123 12 8 0,000 0,02522076 0,06129408 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02522076 0,06123223 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02522076 0,0611705 ! response to antibiotic GO:0046677 11 8 0,000 0,02522076 0,0611089 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02522076 0,06104742 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02522076 0,06098607 ! DNA topological change GO:0006265 12 8 0,000 0,02522076 0,06092484 ! response to tropane GO:0014073 15 8 0,000 0,02522076 0,06086373 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02522076 0,06080275 ! melanosome transport GO:0032402 13 8 0,000 0,02522076 0,06074188 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02522076 0,06068114 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02522076 0,06062052 ! mast cell activation GO:0045576 14 8 0,000 0,02522076 0,06056002 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02522076 0,06049964 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02522076 0,06043938 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02522076 0,06037924 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02522076 0,06031922 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02522076 0,06025932 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02522076 0,06019954 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02522076 0,06013988 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02522076 0,06008034 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02522076 0,06002091 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02522076 0,0599616 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02522076 0,05990241 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02522076 0,05984333 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02522076 0,05978437 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02522076 0,05972553 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02522076 0,0596668 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02522076 0,05960819 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02522076 0,0595497 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02522076 0,05949131 ! hormone catabolic process GO:0042447 17 8 0,000 0,02522076 0,05943305 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02522076 0,05937489 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02522076 0,05931685 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02522076 0,05925893 ! ATP catabolic process GO:0006200 11 8 0,000 0,02522076 0,05920111 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02522076 0,05914341 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02522076 0,05908582 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02522076 0,05902835 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02522076 0,05897098 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02522076 0,05891373 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02522076 0,05885659 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02522076 0,05879955 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02522076 0,05874263 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02522076 0,05868582 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02522076 0,05862912 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02522076 0,05857253 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02522076 0,05851605 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02522076 0,05845967 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02522076 0,05840341 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02522076 0,05834725 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02522076 0,0582912 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,02581092 0,05959796 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,02642724 0,06096254 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,02642724 0,06090415 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,02642724 0,06084587 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,0270495 0,06221903 ! protein import into nucleus GO:0006606 158 80 1,000 0,0270495 0,0621596 ! T cell activation GO:0042110 168 81 1,000 0,02767767 0,06354244 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,02767767 0,06348187 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 0,02767767 0,06342141 ! nuclear import GO:0051170 161 81 1,000 0,02767767 0,06336107 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,02767767 0,06330084 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,0283117 0,06468942 ! response to drug GO:0042493 143 82 1,000 0,0283117 0,06462805 ! response to nutrient GO:0007584 125 82 1,000 0,0283117 0,06456679 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,0283117 0,06450564 ! axon extension GO:0048675 15 9 0,000 0,02832876 0,06448343 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02832876 0,06442249 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02832876 0,06436165 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02832876 0,06430093 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02832876 0,06424033 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02832876 0,06417984 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02832876 0,06411946 ! phosphate transport GO:0006817 19 9 0,000 0,02832876 0,0640592 ! reproductive behavior GO:0019098 19 9 0,000 0,02832876 0,06399905 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02832876 0,06393902 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02832876 0,06387909 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02832876 0,06381928 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02832876 0,06375958 ! GTP metabolic process GO:0046039 9 9 0,000 0,02832876 0,06369999 ! RNA methylation GO:0001510 15 9 0,000 0,02832876 0,06364051 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02832876 0,06358115 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,02832876 0,06352189 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02832876 0,06346275 ! artery development GO:0060840 24 9 0,000 0,02832876 0,06340371 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02832876 0,06334479 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02832876 0,06328597 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02832876 0,06322726 ! chemosensory behavior GO:0007635 20 9 0,000 0,02832876 0,06316867 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02832876 0,06311018 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02832876 0,06305179 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02832876 0,06299352 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02832876 0,06293536 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02832876 0,0628773 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02832876 0,06281935 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02832876 0,0627615 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02832876 0,06270376 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02832876 0,06264613 ! protein targeting to ER GO:0045047 22 9 0,000 0,02832876 0,0625886 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02832876 0,06253118 ! T cell selection GO:0045058 23 9 0,000 0,02832876 0,06247387 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02832876 0,06241666 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02832876 0,06235955 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02832876 0,06230255 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02832876 0,06224565 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02832876 0,06218886 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02832876 0,06213217 ! mannose metabolic process GO:0006013 13 9 0,000 0,02832876 0,06207558 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02832876 0,0620191 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02832876 0,06196272 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02832876 0,06190644 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02832876 0,06185026 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02832876 0,06179419 ! ruffle organization GO:0031529 15 9 0,000 0,02832876 0,06173822 ! retinol metabolic process GO:0042572 18 9 0,000 0,02832876 0,06168234 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02832876 0,06162657 ! behavioral fear response GO:0001662 22 9 0,000 0,02832876 0,0615709 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02832876 0,06151533 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02832876 0,06145987 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02832876 0,0614045 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,02832876 0,06134923 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02832876 0,06129406 ! segment specification GO:0007379 13 9 0,000 0,02832876 0,06123899 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02832876 0,06118401 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02832876 0,06112914 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02832876 0,06107436 ! response to amine stimulus GO:0014075 13 9 0,000 0,02832876 0,06101969 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02832876 0,06096511 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02832876 0,06091063 ! erythrocyte development GO:0048821 15 9 0,000 0,02832876 0,06085624 ! gas homeostasis GO:0033483 16 9 0,000 0,02832876 0,06080195 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02832876 0,06074776 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02832876 0,06069367 ! renal water homeostasis GO:0003091 14 9 0,000 0,02832876 0,06063967 ! postreplication repair GO:0006301 22 9 0,000 0,02832876 0,06058577 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02832876 0,06053196 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02832876 0,06047825 ! icosanoid secretion GO:0032309 15 9 0,000 0,02832876 0,06042464 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02832876 0,06037112 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02832876 0,06031769 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02832876 0,06026436 ! regulation of cell division GO:0051302 15 9 0,000 0,02832876 0,06021112 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02832876 0,06015798 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02832876 0,06010493 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02832876 0,06005197 ! sterol catabolic process GO:0016127 11 9 0,000 0,02832876 0,05999911 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02832876 0,05994634 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02832876 0,05989366 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02832876 0,05984108 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02832876 0,05978859 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02832876 0,05973619 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02832876 0,05968388 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02832876 0,05963166 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02832876 0,05957954 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02832876 0,0595275 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02832876 0,05947556 ! purine base metabolic process GO:0006144 21 9 0,000 0,02832876 0,05942371 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02832876 0,05937194 ! pigment granule transport GO:0051904 17 9 0,000 0,02832876 0,05932027 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02832876 0,05926869 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02832876 0,05921719 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02832876 0,05916579 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02832876 0,05911448 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02832876 0,05906325 ! mitochondrion localization GO:0051646 15 9 0,000 0,02832876 0,05901211 ! response to oxygen levels GO:0070482 176 83 1,000 0,02895155 0,0602573 ! regulation of lyase activity GO:0051339 160 83 1,000 0,02895155 0,06020522 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,02959718 0,06149466 ! nucleosome assembly GO:0006334 122 85 1,000 0,03024854 0,06279378 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,03024854 0,06273965 GO:0002696|positive regulation of leukocyte activation, ! chromatin assembly GO:0031497 124 86 1,000 0,03090559 0,06404725 ! mitochondrion organization GO:0007005 148 86 1,000 0,03090559 0,06399213 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,03142695 0,06501569 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,03142695 0,06495983 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,03142695 0,06490407 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,03142695 0,06484841 ! synapsis GO:0007129 13 10 0,000 0,03142695 0,06479284 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,03142695 0,06473737 ! N-glycan processing GO:0006491 20 10 0,000 0,03142695 0,06468199 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,03142695 0,06462671 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,03142695 0,06457152 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,03142695 0,06451642 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,03142695 0,06446142 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,03142695 0,06440651 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,03142695 0,0643517 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,03142695 0,06429698 ! androgen metabolic process GO:0008209 17 10 0,000 0,03142695 0,06424235 ! phospholipid efflux GO:0033700 16 10 0,000 0,03142695 0,06418782 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,03142695 0,06413337 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,03142695 0,06407902 ! lung alveolus development GO:0048286 26 10 0,000 0,03142695 0,06402476 ! pathogenesis GO:0009405 13 10 0,000 0,03142695 0,0639706 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03142695 0,06391652 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,03142695 0,06386254 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,03142695 0,06380865 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,03142695 0,06375485 ! endoderm development GO:0007492 16 10 0,000 0,03142695 0,06370113 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,03142695 0,06364751 ! arginine catabolic process GO:0006527 13 10 0,000 0,03142695 0,06359398 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,03142695 0,06354054 ! proline metabolic process GO:0006560 13 10 0,000 0,03142695 0,06348719 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,03142695 0,06343393 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,03142695 0,06338076 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,03142695 0,06332768 ! V(D)J recombination GO:0033151 28 10 0,000 0,03142695 0,06327468 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03142695 0,06322178 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,03142695 0,06316896 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,03142695 0,06311623 ! B cell proliferation GO:0042100 18 10 0,000 0,03142695 0,06306359 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,03142695 0,06301104 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,03142695 0,06295857 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,03142695 0,06290619 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,03142695 0,0628539 ! epithelial cell development GO:0002064 20 10 0,000 0,03142695 0,0628017 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,03142695 0,06274958 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,03142695 0,06269755 ! macroautophagy GO:0016236 17 10 0,000 0,03142695 0,06264561 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,03142695 0,06259375 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,03142695 0,06254197 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,03142695 0,06249029 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,03142695 0,06243868 ! copper ion homeostasis GO:0055070 13 10 0,000 0,03142695 0,06238717 ! regulation of bone resorption GO:0045124 25 10 0,000 0,03142695 0,06233573 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,03142695 0,06228439 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,03142695 0,06223312 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,03142695 0,06218195 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,03142695 0,06213085 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,03142695 0,06207984 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,03142695 0,06202891 ! blastoderm segmentation GO:0007350 18 10 0,000 0,03142695 0,06197807 ! response to dsRNA GO:0043331 20 10 0,000 0,03142695 0,06192731 ! DNA ligation GO:0006266 19 10 0,000 0,03142695 0,06187663 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03142695 0,06182604 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,03142695 0,06177553 ! melanosome localization GO:0032400 16 10 0,000 0,03142695 0,0617251 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,03142695 0,06167475 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,03142695 0,06162449 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,03142695 0,0615743 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,03142695 0,0615242 ! mRNA cleavage GO:0006379 17 10 0,000 0,03142695 0,06147418 ! protein sumoylation GO:0016925 15 10 0,000 0,03142695 0,06142425 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,03142695 0,06137439 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03142695 0,06132461 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,03142695 0,06127492 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,03142695 0,0612253 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,03142695 0,06117577 ! salivary gland development GO:0007431 27 10 0,000 0,03142695 0,06112631 ! prophase GO:0051324 15 10 0,000 0,03142695 0,06107694 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03142695 0,06102764 ! apical protein localization GO:0045176 15 10 0,000 0,03142695 0,06097842 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,03142695 0,06092929 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,03142695 0,06088023 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,03142695 0,06083125 ! midbrain development GO:0030901 13 10 0,000 0,03142695 0,06078235 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03142695 0,06073353 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,03142695 0,06068479 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,03142695 0,06063612 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,03142695 0,06058754 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,03142695 0,06053903 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,03142695 0,0604906 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,03142695 0,06044224 ! detection of calcium ion GO:0005513 23 10 0,000 0,03142695 0,06039397 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,03142695 0,06034577 ! blastocyst formation GO:0001825 17 10 0,000 0,03142695 0,06029764 ! cerebellar cortex development GO:0021695 15 10 0,000 0,03142695 0,0602496 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,03142695 0,06020163 ! activation of innate immune response GO:0002218 12 10 0,000 0,03142695 0,06015374 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,03142695 0,06010592 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,03142695 0,06005818 ! response to nicotine GO:0035094 20 10 0,000 0,03142695 0,06001051 ! establishment of cell polarity GO:0030010 16 10 0,000 0,03142695 0,05996292 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,03142695 0,05991541 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,03142695 0,05986797 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,03156829 0,06008964 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 1,000 0,03156829 0,06004214 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,03291047 0,0625455 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,03358987 0,06378629 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,03358987 0,06373598 ! sex differentiation GO:0007548 145 90 1,000 0,03358987 0,06368576 ! protein-DNA complex assembly GO:0065004 130 90 1,000 0,03358987 0,06363561 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03451537 0,06533751 ! respiratory burst GO:0045730 17 11 0,000 0,03451537 0,06528615 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03451537 0,06523486 ! neuron fate specification GO:0048665 17 11 0,000 0,03451537 0,06518366 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03451537 0,06513253 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03451537 0,06508149 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03451537 0,06503053 ! thyroid gland development GO:0030878 26 11 0,000 0,03451537 0,06497964 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03451537 0,06492884 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03451537 0,06487811 ! response to pain GO:0048265 24 11 0,000 0,03451537 0,06482746 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03451537 0,0647769 ! T cell proliferation GO:0042098 26 11 0,000 0,03451537 0,06472641 ! blood vessel remodeling GO:0001974 29 11 0,000 0,03451537 0,064676 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,03451537 0,06462567 ! bone resorption GO:0045453 16 11 0,000 0,03451537 0,06457541 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03451537 0,06452524 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03451537 0,06447514 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03451537 0,06442512 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03451537 0,06437518 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03451537 0,06432531 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03451537 0,06427553 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03451537 0,06422582 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03451537 0,06417618 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03451537 0,06412663 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,03451537 0,06407715 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03451537 0,06402774 ! UV protection GO:0009650 19 11 0,000 0,03451537 0,06397841 ! adult heart development GO:0007512 14 11 0,000 0,03451537 0,06392916 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03451537 0,06387999 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03451537 0,06383088 ! temperature homeostasis GO:0001659 17 11 0,000 0,03451537 0,06378186 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03451537 0,06373291 ! negative regulation of ossification GO:0030279 26 11 0,000 0,03451537 0,06368403 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03451537 0,06363523 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03451537 0,06358651 ! regulation of organ growth GO:0046620 13 11 0,000 0,03451537 0,06353786 ! pigment granule localization GO:0051875 20 11 0,000 0,03451537 0,06348928 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03451537 0,06344078 ! vasoconstriction GO:0042310 18 11 0,000 0,03451537 0,06339235 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03451537 0,063344 ! embryonic axis specification GO:0000578 18 11 0,000 0,03451537 0,06329572 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03451537 0,06324751 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03451537 0,06319938 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03451537 0,06315132 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03451537 0,06310333 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03451537 0,06305541 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03451537 0,06300757 ! zymogen activation GO:0031638 15 11 0,000 0,03451537 0,0629598 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03451537 0,06291211 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03451537 0,06286448 ! nucleosome positioning GO:0016584 15 11 0,000 0,03451537 0,06281693 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03451537 0,06276945 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03451537 0,06272204 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03451537 0,0626747 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,03451537 0,06262744 ! acid secretion GO:0046717 18 11 0,000 0,03451537 0,06258024 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03451537 0,06253312 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03451537 0,06248607 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03451537 0,06243908 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03451537 0,06239217 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03451537 0,06234533 ! cholesterol efflux GO:0033344 19 11 0,000 0,03451537 0,06229856 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03451537 0,06225186 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03451537 0,06220523 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03451537 0,06215867 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,03451537 0,06211218 ! embryonic gut development GO:0048566 15 11 0,000 0,03451537 0,06206576 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03451537 0,0620194 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03451537 0,06197312 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03451537 0,06192691 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03451537 0,06188076 ! defense response to fungus GO:0050832 13 11 0,000 0,03451537 0,06183468 ! developmental induction GO:0031128 19 11 0,000 0,03451537 0,06178868 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,03451537 0,06174274 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03451537 0,06169687 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03451537 0,06165106 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03451537 0,06160533 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03451537 0,06155966 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03451537 0,06151406 ! nucleosome organization GO:0034728 138 92 1,000 0,03496507 0,0622694 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,0356608 0,06346145 ! regulation of membrane potential GO:0042391 164 93 1,000 0,0356608 0,06341454 ! regulation of T cell activation GO:0050863 158 94 1,000 0,03636188 0,0646135 ! forebrain development GO:0030900 188 95 1,000 0,03706828 0,06582014 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03759404 0,06670447 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03759404 0,06665532 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03759404 0,06660624 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03759404 0,06655722 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03759404 0,06650829 ! cartilage condensation GO:0001502 20 12 0,000 0,03759404 0,06645942 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,03759404 0,06641062 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,03759404 0,0663619 ! protein complex disassembly GO:0043241 27 12 0,000 0,03759404 0,06631325 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,03759404 0,06626467 ! hippocampus development GO:0021766 26 12 0,000 0,03759404 0,06621616 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03759404 0,06616772 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03759404 0,06611935 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03759404 0,06607105 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03759404 0,06602282 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03759404 0,06597467 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03759404 0,06592658 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03759404 0,06587856 ! drug transport GO:0015893 16 12 0,000 0,03759404 0,06583062 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03759404 0,06578274 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03759404 0,06573493 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03759404 0,0656872 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03759404 0,06563953 ! focal adhesion formation GO:0048041 35 12 0,000 0,03759404 0,06559193 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03759404 0,0655444 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03759404 0,06549694 ! forebrain cell migration GO:0021885 21 12 0,000 0,03759404 0,06544954 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03759404 0,06540222 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03759404 0,06535496 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03759404 0,06530777 ! entry into host cell GO:0030260 32 12 0,000 0,03759404 0,06526065 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,03759404 0,0652136 ! monoamine transport GO:0015844 18 12 0,000 0,03759404 0,06516662 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03759404 0,0651197 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03759404 0,06507285 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03759404 0,06502607 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03759404 0,06497936 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03759404 0,06493271 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03759404 0,06488613 ! protein homotetramerization GO:0051289 21 12 0,000 0,03759404 0,06483962 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03759404 0,06479317 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03759404 0,06474679 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03759404 0,06470048 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03759404 0,06465423 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03759404 0,06460805 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03759404 0,06456193 ! cranial nerve development GO:0021545 20 12 0,000 0,03759404 0,06451588 ! fucose catabolic process GO:0019317 22 12 0,000 0,03759404 0,0644699 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03759404 0,06442398 ! histone methylation GO:0016571 26 12 0,000 0,03759404 0,06437813 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03759404 0,06433234 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03759404 0,06428662 ! gland morphogenesis GO:0022612 29 12 0,000 0,03759404 0,06424096 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03759404 0,06419536 ! T cell homeostasis GO:0043029 25 12 0,000 0,03759404 0,06414984 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03759404 0,06410437 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03759404 0,06405897 ! spleen development GO:0048536 22 12 0,000 0,03759404 0,06401364 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03759404 0,06396836 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03759404 0,06392316 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03759404 0,06387801 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03759404 0,06383293 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03759404 0,06378792 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,03759404 0,06374297 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03759404 0,06369808 ! response to cold GO:0009409 17 12 0,000 0,03759404 0,06365325 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03759404 0,06360849 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03759404 0,06356379 ! leukocyte differentiation GO:0002521 202 96 1,000 0,03777997 0,06383329 ! protein ubiquitination GO:0016567 217 97 1,000 0,03849689 0,06499896 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,03994629 0,06739887 ! cGMP metabolic process GO:0046068 18 13 0,000 0,040663 0,06856004 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,040663 0,06851203 ! regulation of chemokine production GO:0032642 18 13 0,000 0,040663 0,06846409 ! peroxisomal transport GO:0043574 24 13 0,000 0,040663 0,06841621 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,040663 0,0683684 ! lipid localization GO:0010876 28 13 0,000 0,040663 0,06832066 GO:0019915|lipid storage, ! organelle fusion GO:0048284 32 13 0,000 0,040663 0,06827298 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,040663 0,06822537 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,040663 0,06817783 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,040663 0,06813035 ! endocrine pancreas development GO:0031018 22 13 0,000 0,040663 0,06808294 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,040663 0,06803559 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,040663 0,06798831 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,040663 0,0679411 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,040663 0,06789395 ! methionine metabolic process GO:0006555 27 13 0,000 0,040663 0,06784687 ! plasma membrane organization GO:0007009 24 13 0,000 0,040663 0,06779985 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,040663 0,06775289 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,040663 0,06770601 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,040663 0,06765918 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,040663 0,06761243 ! cytokine metabolic process GO:0042107 22 13 0,000 0,040663 0,06756573 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,040663 0,0675191 ! exocrine system development GO:0035272 32 13 0,000 0,040663 0,06747254 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,040663 0,06742604 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,040663 0,0673796 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,040663 0,06733323 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,040663 0,06728692 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,040663 0,06724067 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,040663 0,06719449 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,040663 0,06714837 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,040663 0,06710232 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,040663 0,06705633 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,040663 0,0670104 ! ribosome assembly GO:0042255 17 13 0,000 0,040663 0,06696453 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,040663 0,06691873 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,040663 0,06687299 ! chromatin silencing GO:0006342 26 13 0,000 0,040663 0,06682731 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,040663 0,06678169 ! regulation of epidermis development GO:0045682 19 13 0,000 0,040663 0,06673614 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,040663 0,06669065 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,040663 0,06664522 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,040663 0,06659985 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,040663 0,06655454 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,040663 0,0665093 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,040663 0,06646412 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,040663 0,066419 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,040663 0,06637393 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,040663 0,06632894 ! embryonic placenta development GO:0001892 23 13 0,000 0,040663 0,066284 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,040663 0,06623912 ! insulin secretion GO:0030073 23 13 0,000 0,040663 0,0661943 ! actin filament polymerization GO:0030041 24 13 0,000 0,040663 0,06614955 ! acrosome reaction GO:0007340 18 13 0,000 0,040663 0,06610485 ! rRNA transcription GO:0009303 25 14 0,000 0,04372227 0,07103024 ! lactation GO:0007595 26 14 0,000 0,04372227 0,07098231 ! reproductive cellular process GO:0048610 20 14 0,000 0,04372227 0,07093445 ! tRNA modification GO:0006400 20 14 0,000 0,04372227 0,07088665 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,04372227 0,07083892 ! water transport GO:0006833 21 14 0,000 0,04372227 0,07079125 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,04372227 0,07074364 ! non-recombinational repair GO:0000726 25 14 0,000 0,04372227 0,0706961 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,04372227 0,07064862 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,04372227 0,0706012 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,04372227 0,07055385 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,04372227 0,07050656 ! RNA polyadenylation GO:0043631 30 14 0,000 0,04372227 0,07045934 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,04372227 0,07041218 ! palate development GO:0060021 31 14 0,000 0,04372227 0,07036508 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,04372227 0,07031804 ! regulated secretory pathway GO:0045055 23 14 0,000 0,04372227 0,07027107 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,04372227 0,07022416 ! arginine metabolic process GO:0006525 17 14 0,000 0,04372227 0,07017731 ! regulation of heart rate GO:0002027 24 14 0,000 0,04372227 0,07013053 ! organic alcohol transport GO:0015850 29 14 0,000 0,04372227 0,0700838 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,04372227 0,07003714 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,04372227 0,06999055 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,04372227 0,06994401 ! neutral amino acid transport GO:0015804 26 14 0,000 0,04372227 0,06989754 ! L-amino acid transport GO:0015807 30 14 0,000 0,04372227 0,06985112 ! stem cell development GO:0048864 43 14 0,000 0,04372227 0,06980477 GO:0019827|stem cell maintenance, ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,04372227 0,06975848 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04372227 0,06971225 ! cerebellum development GO:0021549 21 14 0,000 0,04372227 0,06966609 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,04372227 0,06961998 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,04372227 0,06957394 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,04372227 0,06952795 ! cofactor transport GO:0051181 26 14 0,000 0,04372227 0,06948203 ! NADP metabolic process GO:0006739 24 14 0,000 0,04372227 0,06943617 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,04372227 0,06939036 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,04372227 0,06934462 ! intestinal absorption GO:0050892 25 14 0,000 0,04372227 0,06929894 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,04372227 0,06925332 ! oxygen transport GO:0015671 21 14 0,000 0,04372227 0,06920776 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,04372227 0,06916226 ! male genitalia development GO:0030539 24 14 0,000 0,04372227 0,06911681 ! regulation of RNA stability GO:0043487 32 14 0,000 0,04372227 0,06907143 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,04372227 0,06902611 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04677189 0,07379224 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04677189 0,07374389 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,04677189 0,07369559 ! superoxide anion generation GO:0042554 20 15 0,000 0,04677189 0,07364736 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,04677189 0,0735992 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04677189 0,07355109 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04677189 0,07350305 ! copper ion transport GO:0006825 20 15 0,000 0,04677189 0,07345507 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,04677189 0,07340716 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04677189 0,0733593 ! sulfate transport GO:0008272 23 15 0,000 0,04677189 0,07331151 ! response to cAMP GO:0051591 22 15 0,000 0,04677189 0,07326378 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04677189 0,07321612 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04677189 0,07316851 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04677189 0,07312097 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04677189 0,07307349 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04677189 0,07302607 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04677189 0,07297871 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,04677189 0,07293141 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04677189 0,07288418 ! pituitary gland development GO:0021983 29 15 0,000 0,04677189 0,072837 ! vesicle coating GO:0006901 33 15 0,000 0,04677189 0,07278989 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,04677189 0,07274284 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04677189 0,07269585 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04677189 0,07264892 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,04677189 0,07260205 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04677189 0,07255524 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04677189 0,07250849 ! regulation of vasodilation GO:0042312 26 15 0,000 0,04677189 0,0724618 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04677189 0,07241517 ! histone deacetylation GO:0016575 20 15 0,000 0,04677189 0,0723686 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04677189 0,07232209 ! tissue regeneration GO:0042246 26 15 0,000 0,04677189 0,07227564 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04677189 0,07222925 ! water homeostasis GO:0030104 27 15 0,000 0,04677189 0,07218292 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04677189 0,07213665 ! muscle maintenance GO:0046716 26 15 0,000 0,04677189 0,07209044 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04677189 0,07204428 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04677189 0,07199819 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,04677189 0,07195216 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04677189 0,07190618 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04677189 0,07186026 ! cell killing GO:0001906 29 15 0,000 0,04677189 0,0718144 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04677189 0,0717686 ! detection of bacterium GO:0016045 18 15 0,000 0,04677189 0,07172286 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04677189 0,07167718 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04677189 0,07163155 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04677189 0,07158599 ! peptide hormone processing GO:0016486 23 15 0,000 0,04677189 0,07154048 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04981189 0,07614193 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,04981189 0,07609359 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04981189 0,0760453 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,04981189 0,07599708 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,04981189 0,07594892 ! bone remodeling GO:0046849 27 16 0,000 0,04981189 0,07590082 ! filopodium assembly GO:0046847 32 16 0,000 0,04981189 0,07585278 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04981189 0,07580481 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04981189 0,07575689 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04981189 0,07570903 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,04981189 0,07566124 ! startle response GO:0001964 28 16 0,000 0,04981189 0,0756135 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,04981189 0,07556582 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,04981189 0,07551821 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,04981189 0,07547065 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04981189 0,07542316 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,04981189 0,07537572 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04981189 0,07532835 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04981189 0,07528103 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04981189 0,07523377 ! response to osmotic stress GO:0006970 25 16 0,000 0,04981189 0,07518657 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,04981189 0,07513943 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,04981189 0,07509235 ! fructose metabolic process GO:0006000 25 16 0,000 0,04981189 0,07504533 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04981189 0,07499837 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04981189 0,07495147 ! intermediate filament-based process GO:0045103 32 16 0,000 0,04981189 0,07490462 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,04981189 0,07485784 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04981189 0,07481111 ! axon cargo transport GO:0008088 43 16 0,000 0,04981189 0,07476444 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,04981189 0,07471783 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,04981189 0,07467128 ! DNA replication initiation GO:0006270 27 16 0,000 0,04981189 0,07462478 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,04981189 0,07457834 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,04981189 0,07453196 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,04981189 0,07448564 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,04981189 0,07443938 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,04981189 0,07439317 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04981189 0,07434702 GO:0046466|membrane lipid catabolic process, ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04981189 0,07430093 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04981189 0,07425489 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04981189 0,07420892 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04981189 0,07416299 ! defense response to virus GO:0051607 37 16 0,000 0,04981189 0,07411713 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,05284229 0,07857759 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,05284229 0,07852905 ! metencephalon development GO:0022037 30 17 0,000 0,05284229 0,07848058 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,05284229 0,07843216 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,05284229 0,07838381 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,05284229 0,07833551 ! gene silencing by RNA GO:0031047 36 17 0,000 0,05284229 0,07828728 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,05284229 0,0782391 ! glial cell development GO:0021782 27 17 0,000 0,05284229 0,07819098 ! limbic system development GO:0021761 36 17 0,000 0,05284229 0,07814293 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,05284229 0,07809493 ! adult walking behavior GO:0007628 33 17 0,000 0,05284229 0,07804699 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,05284229 0,0779991 ! heart looping GO:0001947 30 17 0,000 0,05284229 0,07795128 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,05284229 0,07790352 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,05284229 0,07785581 ! myoblast differentiation GO:0045445 45 17 0,000 0,05284229 0,07780816 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,05284229 0,07776057 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,05284229 0,07771304 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,05284229 0,07766557 ! glycine metabolic process GO:0006544 28 17 0,000 0,05284229 0,07761816 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,05284229 0,0775708 ! NAD metabolic process GO:0019674 29 17 0,000 0,05284229 0,0775235 ! membrane budding GO:0006900 37 17 0,000 0,05284229 0,07747626 ! DNA integration GO:0015074 29 17 0,000 0,05284229 0,07742907 ! regulation of protein binding GO:0043393 33 17 0,000 0,05284229 0,07738195 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,05284229 0,07733488 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,05284229 0,07728787 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,05284229 0,07724091 ! genitalia development GO:0048806 30 17 0,000 0,05284229 0,07719401 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,05284229 0,07714717 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,05284229 0,07710039 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,05284229 0,07705366 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,05284229 0,07700699 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,05284229 0,07696037 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,05284229 0,07691382 ! steroid catabolic process GO:0006706 31 17 0,000 0,05284229 0,07686732 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,05284229 0,07682087 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,05284229 0,07677448 ! gas transport GO:0015669 25 17 0,000 0,05284229 0,07672815 ! organic cation transport GO:0015695 31 17 0,000 0,05284229 0,07668187 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,05284229 0,07663565 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,05284229 0,07658948 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,05284229 0,07654337 ! microspike assembly GO:0030035 36 17 0,000 0,05284229 0,07649732 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,05284229 0,07645132 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,05284229 0,07640537 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,05586312 0,08072473 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,05586312 0,08067627 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,05586312 0,08062788 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,05586312 0,08057954 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,05586312 0,08053126 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,05586312 0,08048304 ! memory GO:0007613 31 18 0,000 0,05586312 0,08043487 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05586312 0,08038676 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,05586312 0,08033871 ! patterning of blood vessels GO:0001569 39 18 0,000 0,05586312 0,08029072 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,05586312 0,08024279 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,05586312 0,08019491 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,05586312 0,08014709 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05586312 0,08009933 ! response to retinoic acid GO:0032526 26 18 0,000 0,05586312 0,08005162 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,05586312 0,08000397 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,05586312 0,07995638 ! response to fungus GO:0009620 21 18 0,000 0,05586312 0,07990884 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,05586312 0,07986136 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,05586312 0,07981394 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,05586312 0,07976657 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,05586312 0,07971926 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,05586312 0,079672 ! vitamin transport GO:0051180 27 18 0,000 0,05586312 0,0796248 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,05586312 0,07957766 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,05586312 0,07953057 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,05586312 0,07948354 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,05586312 0,07943657 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,05586312 0,07938965 ! nerve development GO:0021675 28 18 0,000 0,05586312 0,07934278 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,05586312 0,07929597 ! protein secretion GO:0009306 39 19 0,000 0,05887442 0,08352114 ! positive regulation of translation GO:0045727 30 19 0,000 0,05887442 0,08347193 ! negative regulation of defense response GO:0031348 25 19 0,000 0,05887442 0,08342277 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,05887442 0,08337367 ! skin development GO:0043588 36 19 0,000 0,05887442 0,08332462 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,05887442 0,08327564 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,05887442 0,08322671 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,05887442 0,08317784 ! bile acid metabolic process GO:0008206 29 19 0,000 0,05887442 0,08312902 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,05887442 0,08308027 ! pigmentation during development GO:0048066 41 19 0,000 0,05887442 0,08303157 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,05887442 0,08298293 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,05887442 0,08293434 ! heme metabolic process GO:0042168 36 19 0,000 0,05887442 0,08288582 ! actin filament bundle formation GO:0051017 42 19 0,000 0,05887442 0,08283734 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,05887442 0,08278893 ! plasma membrane fusion GO:0045026 28 19 0,000 0,05887442 0,08274057 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,05887442 0,08269227 ! peptide cross-linking GO:0018149 37 19 0,000 0,05887442 0,08264402 ! protein export from nucleus GO:0006611 36 19 0,000 0,05887442 0,08259584 ! heart process GO:0003015 30 19 0,000 0,05887442 0,0825477 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,05887442 0,08249963 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,05887442 0,08245161 ! visual learning GO:0008542 36 19 0,000 0,05887442 0,08240364 ! cellular pigmentation GO:0033059 36 19 0,000 0,05887442 0,08235573 ! G1 phase GO:0051318 40 19 0,000 0,05887442 0,08230788 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,05887442 0,08226008 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,05887442 0,08221234 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,05887442 0,08216465 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,05887442 0,08211702 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,05887442 0,08206944 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,05887442 0,08202192 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,05887442 0,08197446 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,05887442 0,08192704 ! cilium assembly GO:0042384 37 19 0,000 0,05887442 0,08187969 ! peptide hormone secretion GO:0030072 31 19 0,000 0,05887442 0,08183239 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,06187622 0,08595507 ! positive regulation of ossification GO:0045778 47 20 0,000 0,06187622 0,08590547 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,06187622 0,08585593 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,06187622 0,08580644 ! cAMP metabolic process GO:0046058 36 20 0,000 0,06187622 0,08575702 ! response to vitamin GO:0033273 31 20 0,000 0,06187622 0,08570765 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,06187622 0,08565833 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,06187622 0,08560907 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,06187622 0,08555987 ! response to alkaloid GO:0043279 38 20 0,000 0,06187622 0,08551073 ! retinoid metabolic process GO:0001523 32 20 0,000 0,06187622 0,08546164 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,06187622 0,08541261 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,06187622 0,08536364 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,06187622 0,08531472 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,06187622 0,08526585 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,06187622 0,08521705 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,06187622 0,0851683 ! body fluid secretion GO:0007589 31 20 0,000 0,06187622 0,0851196 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,06187622 0,08507096 ! peptide secretion GO:0002790 35 20 0,000 0,06187622 0,08502238 ! stem cell differentiation GO:0048863 53 20 0,000 0,06187622 0,08497385 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,06187622 0,08492537 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,06187622 0,08487696 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,06187622 0,08482859 ! sensory perception of pain GO:0019233 30 20 0,000 0,06187622 0,08478028 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,06187622 0,08473203 ! diencephalon development GO:0021536 34 20 0,000 0,06187622 0,08468383 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,06187622 0,08463569 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,06187622 0,0845876 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,06187622 0,08453957 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,06187622 0,08449159 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,06187622 0,08444366 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,06187622 0,08439579 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,06187622 0,08434798 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,06187622 0,08430021 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,06187622 0,08425251 ! regulation of glucose import GO:0046324 29 20 0,000 0,06187622 0,08420485 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,06187622 0,08415725 ! actin filament-based movement GO:0030048 43 20 0,000 0,06187622 0,08410971 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,06187622 0,08406221 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,06187622 0,08401477 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,06187622 0,08396739 ! regulation of cell killing GO:0031341 42 21 0,000 0,06486854 0,08797841 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,06486854 0,08792885 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,06486854 0,08787934 ! hormone secretion GO:0046879 38 21 0,000 0,06486854 0,08782988 ! glycerol metabolic process GO:0006071 34 21 0,000 0,06486854 0,08778049 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,06486854 0,08773114 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,06486854 0,08768186 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,06486854 0,08763262 ! axis specification GO:0009798 38 21 0,000 0,06486854 0,08758345 ! ovarian follicle development GO:0001541 35 21 0,000 0,06486854 0,08753433 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,06486854 0,08748526 ! smooth muscle contraction GO:0006939 46 21 0,000 0,06486854 0,08743625 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,06486854 0,08738729 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,06486854 0,08733839 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,06486854 0,08728954 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,06486854 0,08724075 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,06486854 0,08719201 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,06486854 0,08714333 ! cytolysis GO:0019835 24 21 0,000 0,06486854 0,0870947 ! vasodilation GO:0042311 39 21 0,000 0,06486854 0,08704613 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,06486854 0,08699761 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,06486854 0,08694914 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,06486854 0,08690073 ! DNA modification GO:0006304 34 21 0,000 0,06486854 0,08685237 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,06486854 0,08680406 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,06486854 0,08675581 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,06486854 0,08670761 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,06486854 0,08665947 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,06486854 0,08661138 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,06486854 0,08656334 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,06486854 0,08651536 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,06486854 0,08646743 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,06486854 0,08641955 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,06486854 0,08637172 ! collagen catabolic process GO:0030574 28 21 0,000 0,06486854 0,08632395 ! sperm-egg recognition GO:0035036 21 21 0,000 0,06486854 0,08627623 ! gut development GO:0048565 39 21 0,000 0,06486854 0,08622857 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,06785141 0,09014384 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,06785141 0,0900941 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,06785141 0,0900444 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,06785141 0,08999476 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,06785141 0,08994518 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,06785141 0,08989565 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,06785141 0,08984618 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,06785141 0,08979676 ! regeneration GO:0031099 41 22 0,000 0,06785141 0,08974739 ! keratinization GO:0031424 28 22 0,000 0,06785141 0,08969808 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,06785141 0,08964882 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,06785141 0,08959962 ! sensory perception of taste GO:0050909 28 22 0,000 0,06785141 0,08955047 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,06785141 0,08950137 ! vacuolar transport GO:0007034 36 22 0,000 0,06785141 0,08945233 ! lysosome organization GO:0007040 41 22 0,000 0,06785141 0,08940334 ! central nervous system neuron development GO:0021954 46 22 0,000 0,06785141 0,08935441 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,06785141 0,08930553 ! fucose metabolic process GO:0006004 39 22 0,000 0,06785141 0,0892567 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,06785141 0,08920792 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,06785141 0,0891592 ! ureteric bud development GO:0001657 43 22 0,000 0,06785141 0,08911054 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,06785141 0,08906192 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,06785141 0,08901336 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,06785141 0,08896485 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,06785141 0,0889164 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,06785141 0,08886799 ! sarcomere organization GO:0045214 30 22 0,000 0,06785141 0,08881964 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,06785141 0,08877134 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,06785141 0,0887231 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,06785141 0,08867491 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,06785141 0,08862677 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,06785141 0,08857868 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,07082487 0,09241033 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,07082487 0,09236024 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,07082487 0,09231021 ! gluconeogenesis GO:0006094 33 23 0,000 0,07082487 0,09226023 ! viral genome replication GO:0019079 41 23 0,000 0,07082487 0,09221031 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,07082487 0,09216044 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,07082487 0,09211062 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,07082487 0,09206086 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,07082487 0,09201115 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,07082487 0,09196149 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,07082487 0,09191189 ! visual behavior GO:0007632 42 23 0,000 0,07082487 0,09186234 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,07082487 0,09181285 ! response to ethanol GO:0045471 46 23 0,000 0,07082487 0,09176341 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,07082487 0,09171402 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,07082487 0,09166468 ! peroxisome organization GO:0007031 37 23 0,000 0,07082487 0,0916154 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,07082487 0,09156617 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,07082487 0,091517 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,07082487 0,09146787 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,07082487 0,0914188 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,07082487 0,09136978 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,07082487 0,09132082 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,07082487 0,0912719 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,07082487 0,09122304 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,07082487 0,09117424 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,07082487 0,09112548 ! fatty acid transport GO:0015908 44 23 0,000 0,07082487 0,09107677 ! platelet activation GO:0030168 37 23 0,000 0,07082487 0,09102812 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,07082487 0,09097952 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,07082487 0,09093097 ! hormone transport GO:0009914 40 23 0,000 0,07082487 0,09088248 ! cell-cell recognition GO:0009988 25 23 0,000 0,07082487 0,09083403 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,07082487 0,09078564 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,07082487 0,0907373 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,07082487 0,09068901 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,07082487 0,09064077 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,07378895 0,09438395 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,07378895 0,0943338 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,07378895 0,0942837 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,07378895 0,09423365 ! vesicle docking GO:0048278 47 24 0,000 0,07378895 0,09418366 ! spinal cord development GO:0021510 47 24 0,000 0,07378895 0,09413373 ! vacuole organization GO:0007033 43 24 0,000 0,07378895 0,09408384 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,07378895 0,09403401 ! digestive system process GO:0022600 39 24 0,000 0,07378895 0,09398423 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,07378895 0,0939345 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,07378895 0,09388483 ! regulation of behavior GO:0050795 43 24 0,000 0,07378895 0,0938352 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,07378895 0,09378563 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,07378895 0,09373612 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,07378895 0,09368665 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,07378895 0,09363724 ! membrane depolarization GO:0051899 39 24 0,000 0,07378895 0,09358788 ! pentose metabolic process GO:0019321 35 24 0,000 0,07378895 0,09353857 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,07378895 0,09348931 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,07378895 0,09344011 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,07378895 0,09339095 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,07378895 0,09334185 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,07378895 0,0932928 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,07378895 0,09324381 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,07378895 0,09319486 ! regulation of amine transport GO:0051952 40 24 0,000 0,07378895 0,09314596 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,07674366 0,09682499 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,07674366 0,09677424 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,07674366 0,09672355 ! phototransduction GO:0007602 33 25 0,000 0,07674366 0,09667291 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,07674366 0,09662232 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,07674366 0,09657178 ! sperm motility GO:0030317 31 25 0,000 0,07674366 0,0965213 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,07674366 0,09647087 ! chromosome condensation GO:0030261 45 25 0,000 0,07674366 0,0964205 ! osteoblast differentiation GO:0001649 60 25 0,000 0,07674366 0,09637017 ! neural crest cell development GO:0014032 54 25 0,000 0,07674366 0,0963199 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,07674366 0,09626968 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,07674366 0,09621952 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,07674366 0,0961694 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,07674366 0,09611934 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,07674366 0,09606933 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,07674366 0,09601937 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,07674366 0,09596947 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,07674366 0,09591961 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,07674366 0,09586981 ! telomere organization GO:0032200 43 25 0,000 0,07674366 0,09582006 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,07674366 0,09577036 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,07674366 0,09572071 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,07968905 0,09934293 ! embryonic pattern specification GO:0009880 44 26 0,000 0,07968905 0,09929148 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,07968905 0,09924009 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,07968905 0,09918875 ! initiation of viral infection GO:0019059 57 26 0,000 0,07968905 0,09913746 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,07968905 0,09908623 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,07968905 0,09903505 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,07968905 0,09898392 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,07968905 0,09893285 ! molting cycle process GO:0022404 50 26 0,000 0,07968905 0,09888182 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,07968905 0,09883085 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,07968905 0,09877994 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,07968905 0,09872907 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,07968905 0,09867826 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,07968905 0,0986275 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,07968905 0,09857679 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,07968905 0,09852613 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,07968905 0,09847553 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,07968905 0,09842498 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,07968905 0,09837448 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,07968905 0,09832403 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,07968905 0,09827363 ! leukocyte proliferation GO:0070661 52 26 0,000 0,07968905 0,09822329 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,07968905 0,09817299 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,07968905 0,09812275 ! neuron fate commitment GO:0048663 48 27 0,000 0,08262514 0,10168598 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,08262514 0,10163399 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,08262514 0,10158206 ! iron ion transport GO:0006826 59 27 0,000 0,08262514 0,10153018 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,08262514 0,10147835 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,08262514 0,10142657 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,08262514 0,10137485 ! fat cell differentiation GO:0045444 50 27 0,000 0,08262514 0,10132318 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,08262514 0,10127157 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,08262514 0,10122 ! autophagy GO:0006914 41 27 0,000 0,08262514 0,10116849 ! male gonad development GO:0008584 44 27 0,000 0,08262514 0,10111703 ! response to toxin GO:0009636 47 27 0,000 0,08262514 0,10106562 ! primary neural tube formation GO:0014020 51 27 0,000 0,08262514 0,10101427 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,08262514 0,10096297 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,08262514 0,10091172 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,08262514 0,10086052 ! glutathione metabolic process GO:0006749 39 27 0,000 0,08262514 0,10080937 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,08262514 0,10075828 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,08262514 0,10070724 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,08262514 0,10065625 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,08555196 0,10416903 ! circadian rhythm GO:0007623 50 28 0,000 0,08555196 0,10411634 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,08555196 0,10406371 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,08555196 0,10401112 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,08555196 0,10395859 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,08555196 0,10390611 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,08555196 0,10385369 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,08555196 0,10380132 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,08555196 0,103749 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,08555196 0,10369673 ! lipid oxidation GO:0034440 43 28 0,000 0,08555196 0,10364452 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,08555196 0,10359236 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,08555196 0,10354025 ! translational initiation GO:0006413 65 29 0,000 0,08846954 0,10701745 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,08846954 0,10696367 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,08846954 0,10690995 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,08846954 0,10685628 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,08846954 0,10680266 ! catechol metabolic process GO:0009712 54 29 0,000 0,08846954 0,1067491 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,08846954 0,10669559 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,08846954 0,10664214 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,08846954 0,10658874 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,08846954 0,10653539 ! cell fate determination GO:0001709 60 29 0,000 0,08846954 0,10648209 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,08846954 0,10642885 ! detection of light stimulus GO:0009583 38 29 0,000 0,08846954 0,10637566 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,08846954 0,10632253 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,08846954 0,10626945 ! regulation of coagulation GO:0050818 46 29 0,000 0,08846954 0,10621642 ! phenol metabolic process GO:0018958 55 30 0,000 0,0913779 0,10965348 ! zinc ion transport GO:0006829 45 30 0,000 0,0913779 0,10959882 ! membrane docking GO:0022406 61 30 0,000 0,0913779 0,10954421 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,0913779 0,10948966 ! regulation of innate immune response GO:0045088 51 30 0,000 0,0913779 0,10943516 ! acute-phase response GO:0006953 49 30 0,000 0,0913779 0,10938071 ! myofibril assembly GO:0030239 47 30 0,000 0,0913779 0,10932632 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,0913779 0,10927198 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,0913779 0,1092177 ! phospholipid transport GO:0015914 51 30 0,000 0,0913779 0,10916347 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,0913779 0,1091093 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,0913779 0,10905518 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,0913779 0,10900111 ! eye morphogenesis GO:0048592 60 30 0,000 0,0913779 0,10894709 ! response to heat GO:0009408 50 30 0,000 0,0913779 0,10889313 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,09427709 0,11229241 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,09427709 0,11223685 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,09427709 0,11218134 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,09427709 0,11212589 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,09427709 0,11207049 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,09427709 0,11201514 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,09427709 0,11195986 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,09427709 0,11190462 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,09427709 0,11184944 ! ovulation cycle process GO:0022602 49 31 0,000 0,09427709 0,11179432 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,09427709 0,11173925 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,09427709 0,11168423 ! peptide transport GO:0015833 55 31 0,000 0,09427709 0,11162927 ! iron ion homeostasis GO:0055072 54 31 0,000 0,09427709 0,11157436 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,09427709 0,1115195 ! mesoderm formation GO:0001707 69 31 0,000 0,09427709 0,1114647 ! natural killer cell activation GO:0030101 45 31 0,000 0,09427709 0,11140995 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,09427709 0,11135526 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,09427709 0,11130062 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,09427709 0,11124604 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,09427709 0,1111915 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,09716711 0,11454389 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,09716711 0,11448779 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,09716711 0,11443176 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,09716711 0,11437577 ! cholesterol transport GO:0030301 56 32 0,000 0,09716711 0,11431984 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,09716711 0,11426397 ! spliceosome assembly GO:0000245 67 32 0,000 0,09716711 0,11420815 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,09716711 0,11415238 ! metanephros development GO:0001656 74 32 0,000 0,09716711 0,11409667 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,09716711 0,11404101 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,09716711 0,11398541 ! muscle cell development GO:0055001 49 32 0,000 0,09716711 0,11392986 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,09716711 0,11387437 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,09716711 0,11381893 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,09716711 0,11376354 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,09716711 0,11370821 ! ovulation cycle GO:0042698 51 32 0,000 0,09716711 0,11365293 ! BMP signaling pathway GO:0030509 64 32 0,000 0,09716711 0,11359771 ! hindbrain development GO:0030902 61 32 0,000 0,09716711 0,11354253 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,09716711 0,11348742 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,09716711 0,11343235 ! gene silencing GO:0016458 65 32 0,000 0,09716711 0,11337734 ! post-embryonic development GO:0009791 69 33 0,000 0,10004802 0,11668227 ! protein targeting to membrane GO:0006612 68 33 0,000 0,10004802 0,11662574 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,10004802 0,11656926 ! ceramide metabolic process GO:0006672 64 33 0,000 0,10004802 0,11651284 ! formation of primary germ layer GO:0001704 72 33 0,000 0,10004802 0,11645647 ! cell fate specification GO:0001708 52 33 0,000 0,10004802 0,11640016 ! sterol transport GO:0015918 57 33 0,000 0,10004802 0,1163439 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,10004802 0,1162877 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,10004802 0,11623154 ! adult locomotory behavior GO:0008344 59 33 0,000 0,10004802 0,11617545 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,10004802 0,11611941 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,10291982 0,11939493 ! glial cell differentiation GO:0010001 63 34 0,000 0,10291982 0,11933739 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,10291982 0,11927991 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,10291982 0,11922248 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,10291982 0,11916511 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,10291982 0,11910779 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,10291982 0,11905053 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,10291982 0,11899332 ! mismatch repair GO:0006298 46 34 0,000 0,10291982 0,11893616 ! spermatid development GO:0007286 63 34 0,000 0,10291982 0,11887906 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,10291982 0,11882202 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,10291982 0,11876503 ! placenta development GO:0001890 53 34 0,000 0,10291982 0,1187081 ! regulation of muscle development GO:0048634 70 35 0,000 0,10578256 0,12195153 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,10578256 0,12189312 ! odontogenesis GO:0042476 66 35 0,000 0,10578256 0,12183477 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,10578256 0,12177648 ! cytokine production GO:0001816 59 35 0,000 0,10578256 0,12171824 ! neural tube formation GO:0001841 67 35 0,000 0,10578256 0,12166006 ! vesicle localization GO:0051648 64 35 0,000 0,10578256 0,12160193 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,10863625 0,12482274 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,10863625 0,12476316 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,10863625 0,12470364 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,10863625 0,12464417 ! positive regulation of cell development GO:0010720 80 36 0,000 0,10863625 0,12458476 ! regulation of proteolysis GO:0030162 72 36 0,000 0,10863625 0,12452541 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,10863625 0,12446611 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,10863625 0,12440687 ! aerobic respiration GO:0009060 55 36 0,000 0,10863625 0,12434768 ! embryonic organ development GO:0048568 57 36 0,000 0,10863625 0,12428855 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,10863625 0,12422948 ! RNA export from nucleus GO:0006405 56 37 0,000 0,11148094 0,12742192 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,11148094 0,12736141 ! meiosis I GO:0007127 65 37 0,000 0,11148094 0,12730097 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,11148094 0,12724058 ! sister chromatid segregation GO:0000819 58 37 0,000 0,11148094 0,12718024 ! actomyosin structure organization GO:0031032 62 37 0,000 0,11148094 0,12711997 ! organic anion transport GO:0015711 68 37 0,000 0,11148094 0,12705975 ! tissue remodeling GO:0048771 76 37 0,000 0,11148094 0,12699959 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,11148094 0,12693949 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,11148094 0,12687944 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,11148094 0,12681945 ! pigment metabolic process GO:0042440 80 37 0,000 0,11148094 0,12675952 ! spermatid differentiation GO:0048515 66 37 0,000 0,11148094 0,12669964 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,11431664 0,12986111 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,11431664 0,12979982 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,11431664 0,1297386 ! nucleus organization GO:0006997 67 38 0,000 0,11431664 0,12967743 ! lipid homeostasis GO:0055088 67 38 0,000 0,11431664 0,12961632 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,11431664 0,12955527 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,11431664 0,12949427 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,11431664 0,12943333 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,11431664 0,12937245 ! glucan metabolic process GO:0044042 62 38 0,000 0,11431664 0,12931163 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,11714338 0,13244689 ! ear morphogenesis GO:0042471 60 39 0,000 0,11714338 0,13238467 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,11714338 0,13232252 ! ion transmembrane transport GO:0034220 66 39 0,000 0,11714338 0,13226043 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,11714338 0,13219839 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,11714338 0,13213641 ! RNA modification GO:0009451 57 39 0,000 0,11714338 0,13207449 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,11714338 0,13201263 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,11996119 0,13512483 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,11996119 0,1350616 ! feeding behavior GO:0007631 59 40 0,000 0,11996119 0,13499843 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,11996119 0,13493531 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,11996119 0,13487226 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,12277011 0,13796585 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,12277011 0,13790144 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,12277011 0,13783709 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,12277011 0,1377728 ! gliogenesis GO:0042063 88 41 0,000 0,12277011 0,13770857 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,12277011 0,1376444 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,12277011 0,13758029 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,12557015 0,1406526 ! regulation of tube size GO:0035150 71 42 0,000 0,12557015 0,14058715 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,12557015 0,14052176 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,12557015 0,14045643 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,12557015 0,14039116 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,12557015 0,14032596 ! regulation of protein secretion GO:0050708 71 42 0,000 0,12557015 0,14026081 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,12557015 0,14019572 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,12836135 0,14324555 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,12836135 0,14317914 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,12836135 0,14311279 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,12836135 0,14304651 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,12836135 0,14298028 ! glucose transport GO:0015758 65 43 0,000 0,12836135 0,14291412 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,12836135 0,14284801 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,12836135 0,14278197 ! neural tube development GO:0021915 77 43 0,000 0,12836135 0,14271599 ! striated muscle contraction GO:0006941 77 43 0,000 0,12836135 0,14265007 ! phagocytosis GO:0006909 90 43 0,000 0,12836135 0,14258421 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,12836135 0,14251842 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,13114373 0,1455405 ! hexose transport GO:0008645 67 44 0,000 0,13114373 0,1454734 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,13114373 0,14540637 ! male sex differentiation GO:0046661 76 44 0,000 0,13114373 0,14533939 ! biopolymer methylation GO:0043414 84 44 0,000 0,13114373 0,14527247 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,13114373 0,14520562 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,13114373 0,14513883 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,13391732 0,14814026 ! glycolysis GO:0006096 65 45 0,000 0,13391732 0,14807218 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,13391732 0,14800417 ! leukocyte migration GO:0050900 68 45 0,000 0,13391732 0,14793621 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,13391732 0,14786832 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,13391732 0,14780049 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,13391732 0,14773272 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,13391732 0,14766502 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,13391732 0,14759738 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,13391732 0,1475298 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,13391732 0,14746228 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,13668215 0,1504379 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,13668215 0,15036911 ! pigmentation GO:0043473 100 46 0,000 0,13668215 0,15030039 ! positive regulation of defense response GO:0031349 76 47 0,000 0,13943824 0,15326104 ! response to calcium ion GO:0051592 81 47 0,000 0,13943824 0,15319106 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,13943824 0,15312114 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,13943824 0,15305128 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,13943824 0,15298149 ! JNK cascade GO:0007254 91 47 0,000 0,13943824 0,15291177 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,13943824 0,1528421 ! methylation GO:0032259 90 47 0,000 0,13943824 0,1527725 ! protein homooligomerization GO:0051260 76 47 0,000 0,13943824 0,15270297 ! Notch signaling pathway GO:0007219 96 48 0,000 0,14218563 0,15564087 ! cellular component disassembly GO:0022411 86 48 0,000 0,14218563 0,15557009 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,14218563 0,15549938 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,14218563 0,15542873 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,14218563 0,15535814 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,14218563 0,15528762 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,14218563 0,15521716 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,14492434 0,15813513 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,14492434 0,15806344 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,14492434 0,15799182 ! regulation of ion transport GO:0043269 77 49 0,000 0,14492434 0,15792027 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,14492434 0,15784878 ! peptide metabolic process GO:0006518 76 49 0,000 0,14492434 0,15777736 ! response to temperature stimulus GO:0009266 76 49 0,000 0,14492434 0,157706 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,14492434 0,1576347 ! endocrine system development GO:0035270 104 49 0,000 0,14492434 0,15756347 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,14492434 0,1574923 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,14492434 0,1574212 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,14492434 0,15735016 ! neuromuscular process GO:0050905 99 50 0,000 0,14765439 0,16024198 ! regulation of ossification GO:0030278 117 50 0,000 0,14765439 0,16016973 ! inner ear development GO:0048839 79 50 0,000 0,14765439 0,16009755 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,14765439 0,16002544 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,14765439 0,15995338 ! viral infectious cycle GO:0019058 99 51 0,000 0,15037582 0,16282818 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,15037582 0,16275494 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,15037582 0,16268175 ! excretion GO:0007588 83 51 0,000 0,15037582 0,16260864 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,15037582 0,16253559 ! chromatin remodeling GO:0006338 109 51 0,000 0,15037582 0,16246261 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,15037582 0,16238969 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,15037582 0,16231683 ! vesicle organization GO:0016050 107 51 0,000 0,15037582 0,16224405 ! regulation of cell shape GO:0008360 125 51 0,000 0,15037582 0,16217132 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,15037582 0,16209867 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,15308865 0,16494908 ! membrane fusion GO:0006944 110 52 0,000 0,15308865 0,16487524 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,15308865 0,16480147 ! amino acid activation GO:0043038 92 52 0,000 0,15308865 0,16472777 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,15308865 0,16465413 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,15579291 0,16748782 ! RNA catabolic process GO:0006401 93 53 0,000 0,15579291 0,16741301 ! regulation of translational initiation GO:0006446 82 53 0,000 0,15579291 0,16733827 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,15579291 0,1672636 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,15579291 0,167189 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,15579291 0,16711446 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,15579291 0,16703999 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,15848862 0,16985462 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,15848862 0,16977899 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,15848862 0,16970343 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,15848862 0,16962794 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,15848862 0,16955252 ! chloride transport GO:0006821 90 55 0,000 0,16117581 0,17235067 ! glucose catabolic process GO:0006007 82 55 0,000 0,16117581 0,1722741 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,16117581 0,1721976 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,16117581 0,17212117 ! gastrulation GO:0007369 112 55 0,000 0,16117581 0,17204481 ! RNA elongation GO:0006354 79 55 0,000 0,16117581 0,17196852 ! nuclear export GO:0051168 97 55 0,000 0,16117581 0,17189229 ! regulation of actin filament length GO:0030832 105 56 0,000 0,16385451 0,17467167 ! sensory perception of smell GO:0007608 80 56 0,000 0,16385451 0,17459431 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,16385451 0,17451702 ! proton transport GO:0015992 94 56 0,000 0,16385451 0,1744398 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,16385451 0,17436265 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,16652475 0,17712579 ! hydrogen transport GO:0006818 97 58 0,000 0,16918655 0,17987752 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,16918655 0,17979807 ! regulation of endocytosis GO:0030100 91 58 0,000 0,16918655 0,17971869 ! adult behavior GO:0030534 99 58 0,000 0,16918655 0,17963938 ! regulation of cellular component size GO:0032535 109 59 0,000 0,17183993 0,18237621 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,17183993 0,1822958 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,17183993 0,18221546 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,17183993 0,18213519 ! DNA catabolic process GO:0006308 86 59 0,000 0,17183993 0,18205499 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,17183993 0,18197486 ! establishment of organelle localization GO:0051656 109 59 0,000 0,17183993 0,1818948 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,17448493 0,18461334 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,17448493 0,18453219 ! regulation of heart contraction GO:0008016 110 60 0,000 0,17448493 0,18445112 ! camera-type eye development GO:0043010 116 60 0,000 0,17448493 0,18437011 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,17448493 0,18428917 ! kidney development GO:0001822 122 60 0,000 0,17448493 0,18420831 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,17712157 0,18690987 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,17712157 0,18682792 ! mesoderm development GO:0007498 119 61 0,000 0,17712157 0,18674605 ! tRNA processing GO:0008033 89 61 0,000 0,17712157 0,18666425 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,17712157 0,18658253 ! ear development GO:0043583 103 62 0,000 0,17974987 0,18926836 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,17974987 0,18918556 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,17974987 0,18910284 ! regulation of mitosis GO:0007088 105 63 0,000 0,18236987 0,19177531 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,18236987 0,19169153 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,18236987 0,19160782 ! detection of external stimulus GO:0009581 91 63 0,000 0,18236987 0,19152418 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,18236987 0,19144062 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,18498159 0,19409756 ! cell redox homeostasis GO:0045454 102 64 0,000 0,18498159 0,19401294 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,18498159 0,19392841 ! single fertilization GO:0007338 75 64 0,000 0,18498159 0,19384394 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,18758504 0,19648656 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,18758504 0,19640105 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,18758504 0,19631562 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 0,000 0,18758504 0,19623027 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,19018027 0,19885864 ! extracellular matrix organization GO:0030198 133 66 0,000 0,19018027 0,19877226 ! secondary metabolic process GO:0019748 116 66 0,000 0,19018027 0,19868595 ! cell projection assembly GO:0030031 120 66 0,000 0,19018027 0,19859971 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,1927673 0,20121394 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,1927673 0,20112668 ! chromosome segregation GO:0007059 113 67 0,000 0,1927673 0,2010395 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,1927673 0,20095239 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,1927673 0,20086536 ! hexose catabolic process GO:0019320 104 67 0,000 0,1927673 0,20077841 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,1927673 0,20069153 ! adaptive immune response GO:0002250 119 67 0,000 0,1927673 0,20060472 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,1927673 0,20051799 ! amino acid transport GO:0006865 125 68 0,000 0,19534615 0,20311272 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,19534615 0,20302498 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,19534615 0,20293732 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,19534615 0,20284973 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,19534615 0,20276222 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,19791684 0,20534192 ! urogenital system development GO:0001655 137 69 0,000 0,19791684 0,20525341 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,19791684 0,20516498 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,19791684 0,20507662 ! antigen processing and presentation GO:0019882 104 69 0,000 0,19791684 0,20498834 ! appendage morphogenesis GO:0035107 135 70 0,000 0,20047941 0,20755312 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,20303387 0,21010731 ! appendage development GO:0048736 136 71 0,000 0,20303387 0,21001698 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,20303387 0,20992673 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,20303387 0,20983655 ! regulation of immune effector process GO:0002697 137 71 0,000 0,20303387 0,20974645 ! acute inflammatory response GO:0002526 113 72 0,000 0,20558026 0,21228588 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,20558026 0,21219481 ! carbohydrate transport GO:0008643 110 72 0,000 0,20558026 0,21210382 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,20558026 0,2120129 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,20558026 0,21192206 ! regulation of blood pressure GO:0008217 125 73 0,000 0,20811859 0,21444682 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,20811859 0,21435502 ! fertilization GO:0009566 90 73 0,000 0,20811859 0,2142633 ! transition metal ion transport GO:0000041 126 74 0,000 0,2106489 0,21677556 ! neurotransmitter transport GO:0006836 123 74 0,000 0,2106489 0,21668288 ! exocytosis GO:0006887 133 74 0,000 0,2106489 0,21659028 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,2106489 0,21649776 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,2106489 0,21640532 ! eye development GO:0001654 143 74 0,000 0,2106489 0,21631296 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,21317121 0,2188097 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,21317121 0,21871639 ! rhythmic process GO:0048511 128 75 0,000 0,21317121 0,21862316 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,21568554 0,22110755 ! defense response to bacterium GO:0042742 89 76 0,000 0,21568554 0,22101338 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,21568554 0,22091929 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,21568554 0,22082528 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,21819192 0,22329637 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,21819192 0,22320143 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,21819192 0,22310657 ! blood coagulation GO:0007596 146 78 0,000 0,22069038 0,22556544 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,22069038 0,22546966 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,22069038 0,22537396 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,22318093 0,22782067 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,22318093 0,22772405 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,22318093 0,22762752 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,22318093 0,22753107 ! response to metal ion GO:0010038 140 80 0,000 0,22566361 0,22996469 ! muscle cell differentiation GO:0042692 159 80 0,000 0,22566361 0,22986733 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,22566361 0,22977005 ! inorganic anion transport GO:0015698 138 80 0,000 0,22566361 0,22967286 ! digestion GO:0007586 112 81 0,000 0,22813843 0,23209347 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,22813843 0,23199538 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,23060543 0,23440501 ! hemostasis GO:0007599 158 84 0,000 0,23551604 0,23929543 ! regulation of ligase activity GO:0051340 142 84 0,000 0,23551604 0,23919442 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,23551604 0,23909349 ! response to unfolded protein GO:0006986 131 85 0,000 0,2379597 0,24147239 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,2379597 0,24137059 ! amine biosynthetic process GO:0009309 138 86 0,000 0,24039563 0,24373868 ! response to inorganic substance GO:0010035 153 86 0,000 0,24039563 0,24363601 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,24039563 0,24353342 ! tube morphogenesis GO:0035239 176 86 0,000 0,24039563 0,24343093 ! alcohol catabolic process GO:0046164 130 86 0,000 0,24039563 0,24332851 ! amine transport GO:0015837 155 86 0,000 0,24039563 0,24322619 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,24282385 0,24557973 ! cellular respiration GO:0045333 135 88 0,000 0,2452444 0,24792354 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,2452444 0,24781941 ! regulation of neurological system process GO:0031644 148 88 0,000 0,2452444 0,24771537 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,2452444 0,24761142 ! cellular defense response GO:0006968 114 89 0,000 0,24765728 0,24994271 ! sterol metabolic process GO:0016125 152 91 0,000 0,25246017 0,25468309 ! response to protein stimulus GO:0051789 149 91 0,000 0,25246017 0,25457635 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,25246017 0,2544697 ! regulation of defense response GO:0031347 149 92 0,000 0,25485023 0,25677121 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,25485023 0,25666373 ! vitamin metabolic process GO:0006766 139 92 0,000 0,25485023 0,25655634 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,25723272 0,25884648 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,25723272 0,25873827 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,25723272 0,25863014 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,25960768 0,26090897 ! female pregnancy GO:0007565 164 94 0,000 0,25960768 0,26080003 ! transcription initiation GO:0006352 153 94 0,000 0,25960768 0,26069118 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,26197512 0,26295876 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,26433507 0,26521692 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,26433507 0,26510637 ! positive regulation of immune response GO:0050778 156 96 0,000 0,26433507 0,26499591 ! detection of stimulus GO:0051606 151 96 0,000 0,26433507 0,26488554 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,26668755 0,26713166 ! response to virus GO:0009615 160 98 0,000 0,26903259 0,26936846 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,26903259 0,26925641 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,26903259 0,26914445 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,2713702 0,2713702