pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6497-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of cell migration GO:0030335 36 36 5,000 2,016E-07 3,715E-04 ! lung development GO:0030324 38 37 5,000 2,393E-07 2,205E-04 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 3,000 3,284E-07 2,018E-04 ! respiratory tube development GO:0030323 40 39 5,000 3,32E-07 1,53E-04 ! respiratory system development GO:0060541 40 39 5,000 3,32E-07 1,224E-04 ! positive regulation of cell motion GO:0051272 39 39 5,000 3,32E-07 1,02E-04 ! regulation of cell migration GO:0030334 71 71 6,000 7,443E-07 1,96E-04 ! positive regulation of MAP kinase activity GO:0043406 50 49 5,000 1,345E-06 3,099E-04 ! regulation of locomotion GO:0040012 79 79 6,000 1,551E-06 3,176E-04 ! regulation of cell motion GO:0051270 79 79 6,000 1,551E-06 2,858E-04 ! protein amino acid autophosphorylation GO:0046777 28 28 4,000 1,583E-06 2,652E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 4,000 3,171E-06 4,871E-04 ! actin cytoskeleton reorganization GO:0031532 5 5 2,000 3,798E-06 5,385E-04 ! embryonic gut development GO:0048566 5 5 2,000 3,798E-06 5E-04 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 2,000 3,798E-06 4,667E-04 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 5,000 4,992E-06 5,751E-04 ! regulation of MAP kinase activity GO:0043405 67 66 5,000 7,943E-06 8,611E-04 ! positive regulation of endothelial cell migration GO:0010595 8 8 2,000 2,094E-05 2,144E-03 ! sex determination GO:0007530 8 8 2,000 2,094E-05 2,031E-03 ! negative regulation of blood coagulation GO:0030195 9 8 2,000 2,094E-05 1,93E-03 ! regulation of protein modification process GO:0031399 79 78 5,000 2,099E-05 1,842E-03 ! regulation of catabolic process GO:0009894 48 47 4,000 2,222E-05 1,861E-03 ! tube development GO:0035295 83 81 5,000 2,607E-05 2,089E-03 ! blood vessel morphogenesis GO:0048514 84 83 5,000 2,998E-05 2,303E-03 ! regulation of intracellular protein transport GO:0033157 25 25 3,000 3,021E-05 2,227E-03 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 2,000 3,124E-05 2,215E-03 ! positive regulation of protein import into nucleus GO:0042307 9 9 2,000 3,124E-05 2,133E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 2,000 3,124E-05 2,057E-03 ! positive regulation of protein kinase activity GO:0045860 89 86 5,000 3,672E-05 2,334E-03 ! response to hypoxia GO:0001666 53 53 4,000 4,019E-05 2,469E-03 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 3,000 4,145E-05 2,465E-03 ! positive regulation of transferase activity GO:0051347 91 88 5,000 4,186E-05 2,411E-03 GO:0033674|positive regulation of kinase activity, ! response to oxygen levels GO:0070482 55 54 4,000 4,405E-05 2,46E-03 ! gut development GO:0048565 10 10 2,000 4,44E-05 2,407E-03 ! negative regulation of coagulation GO:0050819 11 10 2,000 4,44E-05 2,338E-03 ! protein stabilization GO:0050821 10 10 2,000 4,44E-05 2,273E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 2,000 6,073E-05 3,025E-03 GO:0032388|positive regulation of intracellular transport, ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 6,073E-05 2,946E-03 ! blood vessel development GO:0001568 95 94 5,000 6,08E-05 2,873E-03 ! vasculature development GO:0001944 97 96 5,000 6,845E-05 3,154E-03 ! regulation of DNA replication GO:0006275 32 31 3,000 7,272E-05 3,269E-03 ! regulation of intracellular transport GO:0032386 31 31 3,000 7,272E-05 3,191E-03 ! angiogenesis GO:0001525 65 64 4,000 1,004E-04 4,305E-03 ! positive regulation of DNA replication GO:0045740 14 13 2,000 1,042E-04 4,363E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 1,042E-04 4,266E-03 ! negative regulation of protein catabolic process GO:0042177 13 13 2,000 1,042E-04 4,174E-03 ! regulation of endothelial cell migration GO:0010594 13 13 2,000 1,042E-04 4,085E-03 ! positive regulation of locomotion GO:0040017 13 13 2,000 1,042E-04 4E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! regulation of protein catabolic process GO:0042176 35 34 3,000 1,054E-04 3,966E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 3,000 1,184E-04 4,364E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 1,319E-04 4,766E-03 ! regulation of behavior GO:0050795 14 14 2,000 1,319E-04 4,675E-03 ! regulation of blood coagulation GO:0030193 15 14 2,000 1,319E-04 4,586E-03 ! urogenital system development GO:0001655 38 38 3,000 1,642E-04 5,604E-03 ! activation of MAPK activity GO:0000187 39 39 3,000 1,82E-04 6,097E-03 ! positive regulation of catabolic process GO:0009896 16 16 2,000 2,008E-04 6,608E-03 ! regulation of coagulation GO:0050818 17 16 2,000 2,008E-04 6,492E-03 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 2,000 2,426E-04 7,707E-03 ! embryonic organ development GO:0048568 17 17 2,000 2,426E-04 7,577E-03 ! negative regulation of catabolic process GO:0009895 18 18 2,000 2,895E-04 8,894E-03 ! regulation of endothelial cell proliferation GO:0001936 19 19 2,000 3,42E-04 0,01033413 ! regulation of protein stability GO:0031647 19 19 2,000 3,42E-04 0,01016745 ! heart development GO:0007507 90 87 4,000 4,282E-04 0,01252525 ! regulation of protein import into nucleus GO:0042306 21 21 2,000 4,646E-04 0,0133786 ! negative regulation of protein transport GO:0051224 21 21 2,000 4,646E-04 0,01317278 ! regulation of DNA metabolic process GO:0051052 51 50 3,000 4,798E-04 0,01339726 ! nitrogen compound catabolic process GO:0044270 51 50 3,000 4,798E-04 0,0131973 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 1,000 5,312E-04 0,01439604 ! neuron fate specification GO:0048665 5 5 1,000 5,312E-04 0,01418741 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 5,312E-04 0,01398473 ! prostate gland development GO:0030850 5 5 1,000 5,312E-04 0,01378776 ! forebrain regionalization GO:0021871 5 5 1,000 5,312E-04 0,01359626 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 1,000 5,312E-04 0,01341001 GO:0010469|regulation of receptor activity, ! mRNA stabilization GO:0048255 5 5 1,000 5,312E-04 0,0132288 GO:0043489|RNA stabilization, ! neurotransmitter uptake GO:0001504 5 5 1,000 5,312E-04 0,01305241 ! dopamine receptor signaling pathway GO:0007212 5 5 1,000 5,312E-04 0,01288067 ! tyrosine metabolic process GO:0006570 5 5 1,000 5,312E-04 0,01271339 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 1,000 5,312E-04 0,0125504 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 1,000 5,312E-04 0,01239153 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 5,312E-04 0,01223664 ! receptor clustering GO:0043113 5 5 1,000 5,312E-04 0,01208557 ! protein heterooligomerization GO:0051291 5 5 1,000 5,312E-04 0,01193818 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 1,000 5,312E-04 0,01179435 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 1,000 5,312E-04 0,01165394 ! spinal cord motor neuron differentiation GO:0021522 5 5 1,000 5,312E-04 0,01151684 GO:0021517|ventral spinal cord development, ! DNA methylation GO:0006306 5 5 1,000 5,312E-04 0,01138292 GO:0006305|DNA alkylation, ! peptidyl-lysine modification GO:0018205 5 5 1,000 5,312E-04 0,01125208 ! positive regulation of viral reproduction GO:0048524 5 5 1,000 5,312E-04 0,01112422 ! ectodermal gut morphogenesis GO:0048567 5 5 1,000 5,312E-04 0,01099922 GO:0007439|ectodermal gut development, ! blastocyst formation GO:0001825 5 5 1,000 5,312E-04 0,01087701 ! positive regulation of DNA metabolic process GO:0051054 23 22 2,000 5,351E-04 0,01083799 ! maintenance of protein location in cell GO:0032507 23 22 2,000 5,351E-04 0,01072019 ! regulation of protein transport GO:0051223 53 53 3,000 6,001E-04 0,01189287 GO:0070201|regulation of establishment of protein localization, ! cell projection assembly GO:0030031 25 23 2,000 6,122E-04 0,01200304 ! negative regulation of multicellular organismal process GO:0051241 55 54 3,000 6,446E-04 0,01250553 ! glucose homeostasis GO:0042593 24 24 2,000 6,96E-04 0,01336199 GO:0033500|carbohydrate homeostasis, ! maintenance of protein location GO:0045185 25 24 2,000 6,96E-04 0,01322424 ! posttranscriptional regulation of gene expression GO:0010608 98 98 4,000 7,402E-04 0,01391957 ! reproductive developmental process GO:0003006 56 56 3,000 7,405E-04 0,01378584 ! ectoderm development GO:0007398 99 99 4,000 7,752E-04 0,01428702 ! regulation of protein localization GO:0032880 58 57 3,000 7,921E-04 0,01445371 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 7,93E-04 0,01432777 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 7,93E-04 0,01418867 ! cartilage condensation GO:0001502 7 6 1,000 7,93E-04 0,01405224 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 7,93E-04 0,01391841 GO:0050927|positive regulation of positive chemotaxis, ! bile acid metabolic process GO:0008206 6 6 1,000 7,93E-04 0,0137871 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 7,93E-04 0,01365825 ! L-phenylalanine metabolic process GO:0006558 6 6 1,000 7,93E-04 0,01353178 GO:0006559|L-phenylalanine catabolic process, ! regulation of vascular permeability GO:0043114 6 6 1,000 7,93E-04 0,01340764 ! L-amino acid transport GO:0015807 6 6 1,000 7,93E-04 0,01328575 ! regulation of bone resorption GO:0045124 6 6 1,000 7,93E-04 0,01316606 ! cellular metabolic compound salvage GO:0043094 6 6 1,000 7,93E-04 0,01304851 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 7,93E-04 0,01293303 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 7,93E-04 0,01281958 ! localization within membrane GO:0051668 6 6 1,000 7,93E-04 0,01270811 ! negative regulation of cell migration GO:0030336 26 26 2,000 8,848E-04 0,01405763 ! maintenance of location in cell GO:0051651 27 26 2,000 8,848E-04 0,01393748 ! synapse organization GO:0050808 26 26 2,000 8,848E-04 0,01381937 ! carboxylic acid catabolic process GO:0046395 63 61 3,000 1,024E-03 0,0158574 GO:0016054|organic acid catabolic process, ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 1,105E-03 0,01696923 ! pteridine and derivative biosynthetic process GO:0042559 7 7 1,000 1,105E-03 0,01682899 ! negative regulation of lipid metabolic process GO:0045833 7 7 1,000 1,105E-03 0,01669104 ! digestive system development GO:0055123 7 7 1,000 1,105E-03 0,01655534 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! cell differentiation in spinal cord GO:0021515 7 7 1,000 1,105E-03 0,01642183 ! regulation of mRNA processing GO:0050684 7 7 1,000 1,105E-03 0,01629046 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 1,105E-03 0,01616117 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! alpha-beta T cell differentiation GO:0046632 7 7 1,000 1,105E-03 0,01603392 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 1,000 1,105E-03 0,01590865 ! cranial nerve development GO:0021545 7 7 1,000 1,105E-03 0,01578533 ! regulation of mRNA stability GO:0043488 7 7 1,000 1,105E-03 0,0156639 ! positive regulation of cell cycle GO:0045787 29 29 2,000 1,224E-03 0,01722247 ! branching morphogenesis of a tube GO:0048754 29 29 2,000 1,224E-03 0,017092 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 1,224E-03 0,01696349 ! positive regulation of protein transport GO:0051222 29 29 2,000 1,224E-03 0,01683689 ! regulation of response to external stimulus GO:0032101 65 64 3,000 1,226E-03 0,01674293 ! positive regulation of response to external stimulus GO:0032103 30 30 2,000 1,353E-03 0,01833666 ! skeletal system morphogenesis GO:0048705 31 30 2,000 1,353E-03 0,01820282 ! negative regulation of protein metabolic process GO:0051248 66 66 3,000 1,376E-03 0,01837781 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 1,466E-03 0,01944038 ! glycine metabolic process GO:0006544 8 8 1,000 1,466E-03 0,01930152 ! alpha-beta T cell activation GO:0046631 8 8 1,000 1,466E-03 0,01916463 ! nucleoside triphosphate catabolic process GO:0009143 8 8 1,000 1,466E-03 0,01902967 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 1,466E-03 0,01889659 ! regulation of RNA stability GO:0043487 8 8 1,000 1,466E-03 0,01876537 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 1,466E-03 0,01863595 ! aromatic compound biosynthetic process GO:0019438 8 8 1,000 1,466E-03 0,01850831 ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 1,466E-03 0,0183824 ! negative regulation of cell motion GO:0051271 31 31 2,000 1,49E-03 0,01855823 ! morphogenesis of a branching structure GO:0001763 32 32 2,000 1,636E-03 0,02023486 ! maintenance of location GO:0051235 33 32 2,000 1,636E-03 0,02009996 ! positive regulation of cell projection organization GO:0031346 9 9 1,000 1,876E-03 0,02289948 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 1,876E-03 0,02274883 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 1,876E-03 0,02260014 ! regulation of cell-cell adhesion GO:0022407 9 9 1,000 1,876E-03 0,02245339 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 1,000 1,876E-03 0,02230853 ! response to osmotic stress GO:0006970 9 9 1,000 1,876E-03 0,02216552 ! substrate-bound cell migration GO:0006929 9 9 1,000 1,876E-03 0,02202434 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 1,000 1,876E-03 0,02188495 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 1,000 1,876E-03 0,0217473 GO:0015800|acidic amino acid transport, ! histone acetylation GO:0016573 9 9 1,000 1,876E-03 0,02161138 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 1,876E-03 0,02147715 ! regulation of leukocyte migration GO:0002685 9 9 1,000 1,876E-03 0,02134458 ! aromatic amino acid family catabolic process GO:0009074 9 9 1,000 1,876E-03 0,02121363 ! response to metal ion GO:0010038 34 34 2,000 1,953E-03 0,02194959 ! mesoderm development GO:0007498 35 35 2,000 2,125E-03 0,0237379 ! response to inorganic substance GO:0010035 36 36 2,000 2,306E-03 0,02560619 ! regulation of mitosis GO:0007088 37 36 2,000 2,306E-03 0,02545286 GO:0051783|regulation of nuclear division, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 2,000 2,306E-03 0,02530136 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 1,000 2,334E-03 0,02545455 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 2,334E-03 0,02530482 ! pteridine and derivative metabolic process GO:0042558 10 10 1,000 2,334E-03 0,02515684 ! regulation of lipid biosynthetic process GO:0046890 10 10 1,000 2,334E-03 0,02501057 ! reciprocal meiotic recombination GO:0007131 10 10 1,000 2,334E-03 0,024866 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 2,334E-03 0,0247231 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 1,000 2,334E-03 0,02458182 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cellular response to unfolded protein GO:0034620 10 10 1,000 2,334E-03 0,02444215 GO:0030968|endoplasmic reticulum unfolded protein response, ! purine ribonucleoside metabolic process GO:0046128 10 10 1,000 2,334E-03 0,02430406 GO:0042278|purine nucleoside metabolic process, ! nerve development GO:0021675 10 10 1,000 2,334E-03 0,02416752 ! embryonic organ morphogenesis GO:0048562 10 10 1,000 2,334E-03 0,02403251 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 2,334E-03 0,02389899 ! regulation of transcription factor activity GO:0051090 38 37 2,000 2,497E-03 0,02542356 GO:0090046|regulation of transcription regulator activity, ! cellular amino acid catabolic process GO:0009063 38 37 2,000 2,497E-03 0,02528387 ! chromosome segregation GO:0007059 38 38 2,000 2,697E-03 0,02715932 ! RNA elongation GO:0006354 38 38 2,000 2,697E-03 0,02701172 ! signal complex assembly GO:0007172 11 11 1,000 2,839E-03 0,02828597 ! protein amino acid acetylation GO:0006473 11 11 1,000 2,839E-03 0,0281339 ! regulation of viral genome replication GO:0045069 11 11 1,000 2,839E-03 0,02798345 ! spinal cord development GO:0021510 11 11 1,000 2,839E-03 0,0278346 ! apoptotic nuclear changes GO:0030262 11 11 1,000 2,839E-03 0,02768733 ! interaction with host GO:0051701 11 11 1,000 2,839E-03 0,02754161 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 2,839E-03 0,02739741 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 2,839E-03 0,02725471 GO:0006109|regulation of carbohydrate metabolic process, ! aromatic amino acid family metabolic process GO:0009072 11 11 1,000 2,839E-03 0,0271135 ! proximal/distal pattern formation GO:0009954 11 11 1,000 2,839E-03 0,02697374 ! nucleotide-excision repair GO:0006289 40 39 2,000 2,906E-03 0,02746867 ! MAPKKK cascade GO:0000165 82 81 3,000 2,928E-03 0,02753059 ! cell cycle checkpoint GO:0000075 42 41 2,000 3,355E-03 0,03138677 ! amine catabolic process GO:0009310 42 41 2,000 3,355E-03 0,03122825 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 3,391E-03 0,031406 ! heterophilic cell adhesion GO:0007157 12 12 1,000 3,391E-03 0,03124897 ! deoxyribonucleotide catabolic process GO:0009264 12 12 1,000 3,391E-03 0,0310935 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 1,000 3,391E-03 0,03093957 ! somitogenesis GO:0001756 13 12 1,000 3,391E-03 0,03078716 ! synaptogenesis GO:0007416 12 12 1,000 3,391E-03 0,03063624 ! aromatic compound catabolic process GO:0019439 13 12 1,000 3,391E-03 0,0304868 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 3,391E-03 0,03033881 ! negative regulation of translation GO:0017148 12 12 1,000 3,391E-03 0,03019224 ! regulation of cellular localization GO:0060341 86 85 3,000 3,487E-03 0,03089362 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 2,000 3,594E-03 0,03169517 ! reproductive structure development GO:0048608 43 43 2,000 3,844E-03 0,03373425 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 3,989E-03 0,03483987 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 1,000 3,989E-03 0,03467553 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 1,000 3,989E-03 0,03451273 GO:0019692|deoxyribose phosphate metabolic process, ! vasculogenesis GO:0001570 13 13 1,000 3,989E-03 0,03435146 ! response to corticosteroid stimulus GO:0031960 13 13 1,000 3,989E-03 0,03419169 GO:0051384|response to glucocorticoid stimulus, ! receptor metabolic process GO:0043112 14 13 1,000 3,989E-03 0,03403339 ! ureteric bud development GO:0001657 13 13 1,000 3,989E-03 0,03387656 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 3,989E-03 0,03372116 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 1,000 3,989E-03 0,03356718 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of viral reproduction GO:0050792 13 13 1,000 3,989E-03 0,0334146 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 1,000 3,989E-03 0,03326341 ! negative regulation of intracellular transport GO:0032387 13 13 1,000 3,989E-03 0,03311357 ! activation of JUN kinase activity GO:0007257 13 13 1,000 3,989E-03 0,03296508 ! purine nucleotide catabolic process GO:0006195 13 13 1,000 3,989E-03 0,03281791 ! camera-type eye morphogenesis GO:0048593 13 13 1,000 3,989E-03 0,03267206 ! blastocyst development GO:0001824 13 13 1,000 3,989E-03 0,03252749 ! tissue homeostasis GO:0001894 13 13 1,000 3,989E-03 0,0323842 GO:0048871|multicellular organismal homeostasis, ! protein tetramerization GO:0051262 13 13 1,000 3,989E-03 0,03224216 ! regulation of DNA binding GO:0051101 47 45 2,000 4,374E-03 0,03520251 ! phosphoinositide-mediated signaling GO:0048015 45 45 2,000 4,374E-03 0,03504946 ! negative regulation of cell cycle GO:0045786 92 91 3,000 4,455E-03 0,03554244 ! DNA replication GO:0006260 91 91 3,000 4,455E-03 0,03538924 ! neuron fate commitment GO:0048663 14 14 1,000 4,632E-03 0,03663477 ! protein amino acid acylation GO:0043543 14 14 1,000 4,632E-03 0,03647821 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 1,000 4,632E-03 0,03632299 ! D-ribose metabolic process GO:0006014 14 14 1,000 4,632E-03 0,03616908 ! base-excision repair GO:0006284 14 14 1,000 4,632E-03 0,03601646 ! response to organic cyclic substance GO:0014070 15 14 1,000 4,632E-03 0,03586513 ! DNA modification GO:0006304 14 14 1,000 4,632E-03 0,03571507 ! tube morphogenesis GO:0035239 47 46 2,000 4,655E-03 0,03574634 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 2,000 4,655E-03 0,03559801 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 2,000 4,655E-03 0,03545091 ! regulation of response to stress GO:0080134 97 94 3,000 5,001E-03 0,037929 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 2,000 5,249E-03 0,03964762 ! regulation of cell cycle process GO:0010564 50 48 2,000 5,249E-03 0,03948579 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 5,319E-03 0,03984803 ! positive regulation of fibroblast proliferation GO:0048146 15 15 1,000 5,319E-03 0,0396867 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 5,319E-03 0,03952668 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 1,000 5,319E-03 0,03936794 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 5,319E-03 0,03921046 ! deoxyribonucleotide metabolic process GO:0009262 15 15 1,000 5,319E-03 0,03905425 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 5,319E-03 0,03889927 ! chromosome condensation GO:0030261 15 15 1,000 5,319E-03 0,03874552 ! negative regulation of transcription factor activity GO:0043433 16 15 1,000 5,319E-03 0,03859298 GO:0090048|negative regulation of transcription regulator activity, ! negative regulation of cell activation GO:0050866 15 15 1,000 5,319E-03 0,03844163 ! ossification GO:0001503 50 49 2,000 5,562E-03 0,04004528 GO:0060348|bone development, ! gland development GO:0048732 51 49 2,000 5,562E-03 0,03988946 ! regulation of ligase activity GO:0051340 50 49 2,000 5,562E-03 0,03973485 ! negative regulation of transport GO:0051051 51 50 2,000 5,887E-03 0,04188999 ! T cell activation GO:0042110 51 50 2,000 5,887E-03 0,04172888 ! transcription initiation GO:0006352 50 50 2,000 5,887E-03 0,041569 ! anterior/posterior pattern formation GO:0009952 51 50 2,000 5,887E-03 0,04141034 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 1,000 6,05E-03 0,0423959 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of mitosis GO:0045840 16 16 1,000 6,05E-03 0,04223531 GO:0051785|positive regulation of nuclear division, ! cellular response to reactive oxygen species GO:0034614 16 16 1,000 6,05E-03 0,04207594 ! segmentation GO:0035282 17 16 1,000 6,05E-03 0,04191775 ! fatty acid beta-oxidation GO:0006635 16 16 1,000 6,05E-03 0,04176076 ! cell fate specification GO:0001708 16 16 1,000 6,05E-03 0,04160494 ! pentose metabolic process GO:0019321 16 16 1,000 6,05E-03 0,04145027 ! serine family amino acid metabolic process GO:0009069 16 16 1,000 6,05E-03 0,04129675 ! regulation of JUN kinase activity GO:0043506 17 16 1,000 6,05E-03 0,04114436 GO:0043507|positive regulation of JUN kinase activity, ! interphase of mitotic cell cycle GO:0051329 52 51 2,000 6,222E-03 0,04216162 GO:0051325|interphase, ! response to hormone stimulus GO:0009725 102 100 3,000 6,225E-03 0,04202301 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 6,824E-03 0,0459022 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 1,000 6,824E-03 0,04573528 ! tissue remodeling GO:0048771 17 17 1,000 6,824E-03 0,04556957 ! embryonic skeletal system morphogenesis GO:0048704 17 17 1,000 6,824E-03 0,04540506 ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 6,824E-03 0,04524174 ! liver development GO:0001889 17 17 1,000 6,824E-03 0,04507958 ! regulation of cell projection organization GO:0031344 19 18 1,000 7,641E-03 0,05029517 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 7,641E-03 0,05011619 ! meiosis I GO:0007127 18 18 1,000 7,641E-03 0,04993847 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 7,641E-03 0,04976201 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 1,000 7,641E-03 0,04958679 ! response to calcium ion GO:0051592 18 18 1,000 7,641E-03 0,0494128 ! negative regulation of DNA binding GO:0043392 19 18 1,000 7,641E-03 0,04924003 ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 1,000 7,641E-03 0,04906846 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 1,000 7,641E-03 0,04889809 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 7,641E-03 0,04872889 ! extracellular structure organization GO:0043062 56 56 2,000 8,071E-03 0,05129106 ! regulation of binding GO:0051098 60 57 2,000 8,475E-03 0,05367581 ! DNA damage checkpoint GO:0000077 19 19 1,000 8,5E-03 0,05364818 ! multicellular organismal metabolic process GO:0044236 19 19 1,000 8,5E-03 0,05346508 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 8,5E-03 0,05328323 ! metanephros development GO:0001656 19 19 1,000 8,5E-03 0,05310261 ! ribonucleoside metabolic process GO:0009119 19 19 1,000 8,5E-03 0,0529232 ! cellular response to oxidative stress GO:0034599 19 19 1,000 8,5E-03 0,05274501 ! positive regulation of T cell differentiation GO:0045582 19 19 1,000 8,5E-03 0,05256802 ! dorsal/ventral pattern formation GO:0009953 19 19 1,000 8,5E-03 0,0523922 ! eye morphogenesis GO:0048592 19 19 1,000 8,5E-03 0,05221756 ! regulation of cell shape GO:0008360 21 19 1,000 8,5E-03 0,05204408 ! placenta development GO:0001890 19 19 1,000 8,5E-03 0,05187175 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 9,319E-03 0,05668418 ! cellular aromatic compound metabolic process GO:0006725 60 59 2,000 9,319E-03 0,05649772 ! negative regulation of binding GO:0051100 21 20 1,000 9,4E-03 0,05679961 ! neural tube development GO:0021915 21 20 1,000 9,4E-03 0,05661399 ! nucleus organization GO:0006997 20 20 1,000 9,4E-03 0,05642958 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 9,4E-03 0,05624637 ! lipid oxidation GO:0034440 20 20 1,000 9,4E-03 0,05606434 GO:0019395|fatty acid oxidation, ! protein polymerization GO:0051258 65 60 2,000 9,759E-03 0,05801922 ! proteasomal protein catabolic process GO:0010498 62 61 2,000 0,01021088 0,06051016 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 0,01034038 0,06108115 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 0,01034038 0,060886 ! mammary gland development GO:0030879 23 21 1,000 0,01034038 0,06069209 ! organic anion transport GO:0015711 21 21 1,000 0,01034038 0,06049942 ! DNA integrity checkpoint GO:0031570 21 21 1,000 0,01034038 0,06030797 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 0,01034038 0,06011772 ! morphogenesis of an epithelium GO:0002009 63 62 2,000 0,01067473 0,06186645 GO:0060429|epithelium development, ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 0,0113209 0,06540572 GO:0090047|positive regulation of transcription regulator activity, ! sister chromatid segregation GO:0000819 22 22 1,000 0,0113209 0,06520132 ! odontogenesis GO:0042476 22 22 1,000 0,0113209 0,0649982 ! embryonic skeletal system development GO:0048706 22 22 1,000 0,0113209 0,06479635 ! male sex differentiation GO:0046661 22 22 1,000 0,0113209 0,06459574 ! biopolymer methylation GO:0043414 22 22 1,000 0,0113209 0,06439637 GO:0032259|methylation, ! positive regulation of lymphocyte differentiation GO:0045621 22 22 1,000 0,0113209 0,06419823 ! fatty acid catabolic process GO:0009062 23 22 1,000 0,0113209 0,0640013 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 1,000 0,0113209 0,06380558 ! positive regulation of cellular component organization GO:0051130 65 65 2,000 0,01213902 0,06820796 ! epithelial cell differentiation GO:0030855 23 23 1,000 0,01234078 0,06913087 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 0,01234078 0,06892138 ! positive regulation of growth GO:0045927 23 23 1,000 0,01234078 0,06871316 ! calcium-mediated signaling GO:0019722 23 23 1,000 0,01234078 0,06850619 ! regulation of JNK cascade GO:0046328 25 23 1,000 0,01234078 0,06830047 ! Ras protein signal transduction GO:0007265 69 67 2,000 0,01317635 0,07270663 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 1,000 0,01339939 0,07371667 ! heterocycle biosynthetic process GO:0018130 24 24 1,000 0,01339939 0,07349727 ! T cell differentiation GO:0030217 24 24 1,000 0,01339939 0,07327918 ! nucleotide catabolic process GO:0009166 24 24 1,000 0,01339939 0,07306238 ! androgen receptor signaling pathway GO:0030521 24 24 1,000 0,01339939 0,07284685 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 0,01339939 0,0726326 ! regionalization GO:0003002 70 69 2,000 0,01426303 0,07708728 ! regulation of mitotic cell cycle GO:0007346 72 69 2,000 0,01426303 0,07686188 ! regulation of gene-specific transcription GO:0032583 25 25 1,000 0,01449614 0,07789035 ! endosome transport GO:0016197 25 25 1,000 0,01449614 0,07766392 ! positive regulation of DNA binding GO:0043388 26 25 1,000 0,01449614 0,07743881 ! heart morphogenesis GO:0003007 25 25 1,000 0,01449614 0,077215 ! positive regulation of transport GO:0051050 71 70 2,000 0,01482497 0,07873897 ! growth GO:0040007 70 70 2,000 0,01482497 0,07851271 ! negative regulation of signal transduction GO:0009968 71 71 2,000 0,01539937 0,08132101 ! regulation of cell activation GO:0050865 71 71 2,000 0,01539937 0,08108866 ! positive regulation of binding GO:0051099 27 26 1,000 0,01563042 0,08207084 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 1,000 0,01563042 0,08183768 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 1,000 0,01563042 0,08160585 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 1,000 0,01563042 0,08137532 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01563042 0,08114609 ! response to insulin stimulus GO:0032868 28 26 1,000 0,01563042 0,08091816 ! regulation of neurotransmitter levels GO:0001505 31 27 1,000 0,01680164 0,08673786 ! cAMP-mediated signaling GO:0019933 27 27 1,000 0,01680164 0,08649557 ! cell growth GO:0016049 27 27 1,000 0,01680164 0,08625464 ! response to oxidative stress GO:0006979 76 75 2,000 0,01782205 0,09123897 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 1,000 0,0180092 0,09194172 GO:0007254|JNK cascade, ! histone modification GO:0016570 28 28 1,000 0,0180092 0,09168774 ! developmental growth GO:0048589 28 28 1,000 0,0180092 0,09143515 ! cartilage development GO:0051216 29 28 1,000 0,0180092 0,09118396 ! negative regulation of cell communication GO:0010648 76 76 2,000 0,01845912 0,0932059 ! viral reproductive process GO:0022415 29 29 1,000 0,01925254 0,09694652 ! regulation of gene expression, epigenetic GO:0040029 29 29 1,000 0,01925254 0,09668237 ! covalent chromatin modification GO:0016569 29 29 1,000 0,01925254 0,09641964 ! response to UV GO:0009411 29 29 1,000 0,01925254 0,09615834 ! microtubule-based movement GO:0007018 82 78 2,000 0,01977109 0,09848139 ! response to reactive oxygen species GO:0000302 31 30 1,000 0,02053107 0,10199127 ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,02053107 0,1017171 GO:0010863|positive regulation of phospholipase C activity, ! vascular process in circulatory system GO:0003018 31 30 1,000 0,02053107 0,1014444 ! lymphocyte activation GO:0046649 82 81 2,000 0,0218338 0,10759278 ! lipid catabolic process GO:0016042 82 81 2,000 0,0218338 0,10730586 ! camera-type eye development GO:0043010 31 31 1,000 0,02184423 0,10707156 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,02184423 0,10678755 ! nucleoside metabolic process GO:0009116 31 31 1,000 0,02184423 0,10650505 ! lipid modification GO:0030258 32 32 1,000 0,02319145 0,11277529 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,02319145 0,11247851 ! cell maturation GO:0048469 32 32 1,000 0,02319145 0,11218329 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,02319145 0,11188962 ! kidney development GO:0001822 32 32 1,000 0,02319145 0,11159748 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,02319145 0,11130686 ! regulation of cellular response to stress GO:0080135 35 33 1,000 0,02457217 0,11762732 ! amino acid transport GO:0006865 33 33 1,000 0,02457217 0,11732258 ! nitrogen compound biosynthetic process GO:0044271 86 85 2,000 0,0247613 0,1179201 ! positive regulation of response to stimulus GO:0048584 86 85 2,000 0,0247613 0,11761618 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 2,000 0,02552483 0,12093128 ! regulation of angiogenesis GO:0045765 35 34 1,000 0,02598586 0,12279985 ! regulation of bone remodeling GO:0046850 34 34 1,000 0,02598586 0,12248578 ! coenzyme biosynthetic process GO:0009108 34 34 1,000 0,02598586 0,12217332 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 1,000 0,02598586 0,12186245 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 0,02598586 0,12155315 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 0,02598586 0,12124542 ! viral reproduction GO:0016032 34 34 1,000 0,02598586 0,12093925 ! regulation of cytokine biosynthetic process GO:0042035 35 35 1,000 0,02743196 0,12734787 ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,02743196 0,1270279 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,02743196 0,12670953 ! regulation of tissue remodeling GO:0034103 35 35 1,000 0,02743196 0,12639276 ! response to steroid hormone stimulus GO:0048545 35 35 1,000 0,02743196 0,12607757 ! brain development GO:0007420 91 90 2,000 0,02870545 0,13160233 ! embryonic limb morphogenesis GO:0030326 36 36 1,000 0,02890994 0,13221095 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,02890994 0,1318837 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,02890994 0,13155806 ! heterocycle catabolic process GO:0046700 36 36 1,000 0,02890994 0,13123403 ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 0,02890994 0,13091158 ! gonad development GO:0008406 36 36 1,000 0,02890994 0,13059072 ! regulation of lipase activity GO:0060191 36 36 1,000 0,02890994 0,13027143 ! coagulation GO:0050817 39 36 1,000 0,02890994 0,12995369 GO:0007596|blood coagulation, ! positive regulation of immune system process GO:0002684 92 92 2,000 0,0303715 0,13619141 ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 0,03041926 0,1360745 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! meiosis GO:0007126 37 37 1,000 0,03041926 0,13574502 GO:0051327|M phase of meiotic cell cycle, ! response to drug GO:0042493 37 37 1,000 0,03041926 0,13541713 ! eye development GO:0001654 37 37 1,000 0,03041926 0,13509082 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,03041926 0,13476609 ! adaptive immune response GO:0002250 37 37 1,000 0,03041926 0,13444291 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! tissue morphogenesis GO:0048729 94 93 2,000 0,03122341 0,13766684 ! neurotransmitter transport GO:0006836 40 38 1,000 0,0319594 0,14057558 ! cell-matrix adhesion GO:0007160 39 38 1,000 0,0319594 0,14024087 ! meiotic cell cycle GO:0051321 38 38 1,000 0,0319594 0,13990776 ! axon guidance GO:0007411 39 38 1,000 0,0319594 0,13957622 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 0,0319594 0,13924626 ! regulation of homeostatic process GO:0032844 38 38 1,000 0,0319594 0,13891784 ! pattern specification process GO:0007389 96 94 2,000 0,03208788 0,13914817 ! epidermis development GO:0008544 94 94 2,000 0,03208788 0,13882153 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 0,03352983 0,14472009 ! hemostasis GO:0007599 42 39 1,000 0,03352983 0,14438196 ! response to unfolded protein GO:0006986 39 39 1,000 0,03352983 0,1440454 ! nucleoside monophosphate metabolic process GO:0009123 39 39 1,000 0,03352983 0,14371041 ! regulation of MAPKKK cascade GO:0043408 41 39 1,000 0,03352983 0,14337698 ! positive regulation of T cell activation GO:0050870 39 39 1,000 0,03352983 0,14304509 ! developmental maturation GO:0021700 39 39 1,000 0,03352983 0,14271473 ! lymphocyte differentiation GO:0030098 39 39 1,000 0,03352983 0,14238589 ! limb development GO:0060173 39 39 1,000 0,03352983 0,14205857 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! protein oligomerization GO:0051259 39 39 1,000 0,03352983 0,14173275 ! regulation of cell growth GO:0001558 97 96 2,000 0,03385445 0,14277747 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 0,03513005 0,1478189 ! DNA catabolic process GO:0006308 41 40 1,000 0,03513005 0,14748219 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 0,03513005 0,147147 ! rRNA transcription GO:0009303 5 5 0,000 0,03652898 0,15265966 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,03652898 0,15231428 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,03652898 0,15197045 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,03652898 0,15162818 ! reproductive cellular process GO:0048610 5 5 0,000 0,03652898 0,15128744 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,03652898 0,15094823 ! metencephalon development GO:0022037 5 5 0,000 0,03652898 0,15061054 ! water transport GO:0006833 5 5 0,000 0,03652898 0,15027435 GO:0042044|fluid transport, ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,03652898 0,14993967 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,03652898 0,14960647 ! glycerol metabolic process GO:0006071 5 5 0,000 0,03652898 0,14927475 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,03652898 0,14894449 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,03652898 0,1486157 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,03652898 0,14828835 ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,03652898 0,14796244 ! filopodium assembly GO:0046847 7 5 0,000 0,03652898 0,14763796 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,03652898 0,1473149 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,03652898 0,14699325 ! GTP metabolic process GO:0046039 5 5 0,000 0,03652898 0,14667301 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,03652898 0,14635415 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,03652898 0,14603668 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,03652898 0,14572058 GO:0001956|positive regulation of neurotransmitter secretion, ! social behavior GO:0035176 5 5 0,000 0,03652898 0,14540585 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,03652898 0,14509248 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,03652898 0,14478045 ! memory GO:0007613 5 5 0,000 0,03652898 0,14446976 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,03652898 0,14416041 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,03652898 0,14385237 ! response to lipid GO:0033993 5 5 0,000 0,03652898 0,14354565 ! erythrocyte maturation GO:0043249 5 5 0,000 0,03652898 0,14324023 ! hippocampus development GO:0021766 6 5 0,000 0,03652898 0,14293612 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,03652898 0,14263328 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,03652898 0,14233173 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,03652898 0,14203146 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,03652898 0,14173244 ! mechanosensory behavior GO:0007638 5 5 0,000 0,03652898 0,14143469 ! heart looping GO:0001947 5 5 0,000 0,03652898 0,14113818 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,03652898 0,14084291 ! response to interferon-gamma GO:0034341 5 5 0,000 0,03652898 0,14054887 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,03652898 0,14025606 ! endocrine pancreas development GO:0031018 5 5 0,000 0,03652898 0,13996447 ! pH reduction GO:0045851 5 5 0,000 0,03652898 0,13967409 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,03652898 0,13938491 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,03652898 0,13909692 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,03652898 0,13881012 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,03652898 0,13852451 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,03652898 0,13824006 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,03652898 0,13795678 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,03652898 0,13767466 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,03652898 0,13739369 ! adrenal gland development GO:0030325 5 5 0,000 0,03652898 0,13711387 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,03652898 0,13683518 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,03652898 0,13655763 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,03652898 0,13628119 ! astrocyte differentiation GO:0048708 5 5 0,000 0,03652898 0,13600588 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,03652898 0,13573167 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,03652898 0,13545857 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,03652898 0,13518657 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microtubule nucleation GO:0007020 5 5 0,000 0,03652898 0,13491565 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,03652898 0,13464582 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,03652898 0,13437707 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,03652898 0,13410938 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,03652898 0,13384276 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,03652898 0,1335772 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,03652898 0,13331269 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,03652898 0,13304923 ! response to ATP GO:0033198 5 5 0,000 0,03652898 0,13278681 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,03652898 0,13252541 ! regulation of appetite GO:0032098 5 5 0,000 0,03652898 0,13226505 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,03652898 0,13200571 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,03652898 0,13174738 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,03652898 0,13149006 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,03652898 0,13123374 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03652898 0,13097842 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,03652898 0,1307241 ! fear response GO:0042596 5 5 0,000 0,03652898 0,13047076 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,03652898 0,13021839 ! retinol metabolic process GO:0042572 5 5 0,000 0,03652898 0,12996701 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,03652898 0,12971659 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,03652898 0,12946713 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,03652898 0,12921864 ! parturition GO:0007567 5 5 0,000 0,03652898 0,12897109 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03652898 0,12872449 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,03652898 0,12847884 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,03652898 0,12823411 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,03652898 0,12799032 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,03652898 0,12774746 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,03652898 0,12750551 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,03652898 0,12726448 ! response to UV-B GO:0010224 5 5 0,000 0,03652898 0,12702436 ! oligodendrocyte development GO:0014003 5 5 0,000 0,03652898 0,12678514 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,03652898 0,12654682 ! activated T cell proliferation GO:0050798 5 5 0,000 0,03652898 0,1263094 ! interaction with symbiont GO:0051702 5 5 0,000 0,03652898 0,12607287 ! cellular extravasation GO:0045123 5 5 0,000 0,03652898 0,12583722 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,03652898 0,12560244 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,03652898 0,12536855 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,03652898 0,12513552 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,03652898 0,12490336 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,03652898 0,12467206 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,03652898 0,12444161 ! response to amine stimulus GO:0014075 5 5 0,000 0,03652898 0,12421201 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,03652898 0,12398326 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,03652898 0,12375535 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,03652898 0,12352828 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,03652898 0,12330203 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,03652898 0,12307662 ! neuron recognition GO:0008038 5 5 0,000 0,03652898 0,12285203 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,03652898 0,12262825 ! decidualization GO:0046697 5 5 0,000 0,03652898 0,12240529 ! hair follicle maturation GO:0048820 5 5 0,000 0,03652898 0,12218314 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,03652898 0,12196179 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,03652898 0,12174125 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,03652898 0,1215215 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,03652898 0,12130254 ! postreplication repair GO:0006301 5 5 0,000 0,03652898 0,12108437 ! cellular pigmentation GO:0033059 5 5 0,000 0,03652898 0,12086698 ! histone methylation GO:0016571 5 5 0,000 0,03652898 0,12065038 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03652898 0,12043454 ! T cell lineage commitment GO:0002360 5 5 0,000 0,03652898 0,12021948 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,03652898 0,12000519 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,03652898 0,11979166 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,03652898 0,11957888 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,03652898 0,11936686 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,03652898 0,11915559 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,03652898 0,11894507 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,03652898 0,11873529 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,03652898 0,11852625 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,03652898 0,11831794 ! sterol catabolic process GO:0016127 5 5 0,000 0,03652898 0,11811037 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,03652898 0,11790352 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,03652898 0,1176974 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,03652898 0,11749199 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,03652898 0,1172873 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,03652898 0,11708332 ! zymogen activation GO:0031638 5 5 0,000 0,03652898 0,11688005 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,03652898 0,11667749 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,03652898 0,11647562 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,03652898 0,11627446 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,03652898 0,11607398 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,03652898 0,1158742 ! nucleosome positioning GO:0016584 5 5 0,000 0,03652898 0,1156751 ! regulation of isotype switching GO:0045191 5 5 0,000 0,03652898 0,11547669 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,03652898 0,11527896 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,03652898 0,1150819 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,03652898 0,11488551 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,03652898 0,1146898 ! NADPH regeneration GO:0006740 5 5 0,000 0,03652898 0,11449475 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,03652898 0,11430036 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,03652898 0,11410663 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,03652898 0,11391355 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,03652898 0,11372113 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,03652898 0,11352936 ! sarcomere organization GO:0045214 5 5 0,000 0,03652898 0,11333823 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,03652898 0,11314775 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,03652898 0,1129579 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,03652898 0,11276869 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,03652898 0,11258012 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,03652898 0,11239217 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,03652898 0,11220485 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,03652898 0,11201815 ! spleen development GO:0048536 5 5 0,000 0,03652898 0,11183208 ! male genitalia development GO:0030539 5 5 0,000 0,03652898 0,11164662 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,03652898 0,11146177 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,03652898 0,11127754 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,03652898 0,11109391 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,03652898 0,11091089 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,03652898 0,11072847 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,03652898 0,11054665 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,03652898 0,11036543 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,03652898 0,1101848 ! ATP catabolic process GO:0006200 5 5 0,000 0,03652898 0,11000476 ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,03652898 0,1098253 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,03652898 0,10964643 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,03652898 0,10946815 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,03652898 0,10929044 ! activation of innate immune response GO:0002218 5 5 0,000 0,03652898 0,10911331 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,03652898 0,10893675 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,03652898 0,10876076 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,03652898 0,10858534 ! muscle adaptation GO:0043500 5 5 0,000 0,03652898 0,10841048 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,03652898 0,10823619 ! embryonic heart tube development GO:0035050 5 5 0,000 0,03652898 0,10806246 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,03652898 0,10788928 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,03652898 0,10771666 ! defense response to fungus GO:0050832 5 5 0,000 0,03652898 0,10754458 ! lysogeny GO:0030069 5 5 0,000 0,03652898 0,10737306 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,03652898 0,10720209 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,03652898 0,10703165 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,03652898 0,10686176 ! response to nicotine GO:0035094 5 5 0,000 0,03652898 0,10669241 ! establishment of cell polarity GO:0030010 5 5 0,000 0,03652898 0,10652359 ! mitochondrion localization GO:0051646 5 5 0,000 0,03652898 0,10635531 ! nucleus localization GO:0051647 5 5 0,000 0,03652898 0,10618756 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,03652898 0,10602033 ! anti-apoptosis GO:0006916 100 99 2,000 0,03659797 0,10605356 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,03675954 0,10635453 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,0384178 0,11097807 ! cell-substrate adhesion GO:0031589 43 42 1,000 0,0384178 0,1108044 ! development of primary sexual characteristics GO:0045137 42 42 1,000 0,0384178 0,11063127 ! protein ubiquitination GO:0016567 43 42 1,000 0,0384178 0,11045867 ! negative regulation of ligase activity GO:0051352 43 42 1,000 0,0384178 0,11028662 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 1,000 0,0384178 0,1101151 ! forebrain development GO:0030900 43 42 1,000 0,0384178 0,10994412 ! one-carbon metabolic process GO:0006730 42 42 1,000 0,0384178 0,10977366 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 1,000 0,04010434 0,11441532 ! mitochondrion organization GO:0007005 44 43 1,000 0,04010434 0,11423848 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,04010434 0,11406218 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 0,04181865 0,11875466 ! protein import into nucleus GO:0006606 44 44 1,000 0,04181865 0,11857197 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,04181865 0,11838983 ! positive regulation of lymphocyte activation GO:0051251 44 44 1,000 0,04181865 0,11820825 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,04356026 0,12294267 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 0,04356026 0,12275468 ! nuclear import GO:0051170 45 45 1,000 0,04356026 0,12256727 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,04367618 0,12270611 ! axon extension GO:0048675 7 6 0,000 0,04367618 0,12251934 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,04367618 0,12233314 ! tRNA modification GO:0006400 6 6 0,000 0,04367618 0,1221475 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,04367618 0,12196243 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,04367618 0,12177792 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,04367618 0,12159397 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,04367618 0,12141057 ! regulation of S phase GO:0033261 6 6 0,000 0,04367618 0,12122772 ! myotube differentiation GO:0014902 6 6 0,000 0,04367618 0,12104542 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,04367618 0,12086367 ! bone remodeling GO:0046849 6 6 0,000 0,04367618 0,12068247 ! N-glycan processing GO:0006491 6 6 0,000 0,04367618 0,1205018 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,04367618 0,12032168 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,04367618 0,1201421 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,04367618 0,11996305 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,04367618 0,11978453 ! RNA methylation GO:0001510 6 6 0,000 0,04367618 0,11960655 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,04367618 0,11942909 ! succinate metabolic process GO:0006105 7 6 0,000 0,04367618 0,11925216 ! artery development GO:0060840 6 6 0,000 0,04367618 0,11907575 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,04367618 0,11889986 ! androgen metabolic process GO:0008209 6 6 0,000 0,04367618 0,11872449 ! estrogen metabolic process GO:0008210 6 6 0,000 0,04367618 0,11854964 ! limbic system development GO:0021761 7 6 0,000 0,04367618 0,1183753 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,04367618 0,11820148 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,04367618 0,11802816 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,04367618 0,11785535 ! pathogenesis GO:0009405 6 6 0,000 0,04367618 0,11768305 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,04367618 0,11751125 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,04367618 0,11733995 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,04367618 0,11716915 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,04367618 0,11699885 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,04367618 0,11682904 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,04367618 0,11665972 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,04367618 0,11649089 ! arginine metabolic process GO:0006525 6 6 0,000 0,04367618 0,11632255 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,04367618 0,1161547 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,04367618 0,11598733 ! glutamate catabolic process GO:0006538 7 6 0,000 0,04367618 0,11582044 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,04367618 0,11565403 GO:0010833|telomere maintenance via telomere lengthening, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,04367618 0,1154881 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,04367618 0,11532264 ! ER overload response GO:0006983 6 6 0,000 0,04367618 0,11515766 ! V(D)J recombination GO:0033151 6 6 0,000 0,04367618 0,11499315 ! focal adhesion formation GO:0048041 7 6 0,000 0,04367618 0,11482911 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,04367618 0,11466554 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 0,04367618 0,11450243 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,04367618 0,11433978 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,04367618 0,1141776 ! regulation of heart rate GO:0002027 6 6 0,000 0,04367618 0,11401587 ! lipid digestion GO:0044241 6 6 0,000 0,04367618 0,1138546 ! asymmetric protein localization GO:0008105 6 6 0,000 0,04367618 0,11369379 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,04367618 0,11353344 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,04367618 0,11337353 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,04367618 0,11321407 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,04367618 0,11305506 ! ruffle organization GO:0031529 6 6 0,000 0,04367618 0,1128965 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,04367618 0,11273838 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,04367618 0,11258071 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,04367618 0,11242347 ! neutral amino acid transport GO:0015804 6 6 0,000 0,04367618 0,11226667 ! bone mineralization GO:0030282 6 6 0,000 0,04367618 0,11211031 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,04367618 0,11195439 ! negative regulation of ossification GO:0030279 6 6 0,000 0,04367618 0,1117989 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,04367618 0,11164384 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,04367618 0,1114892 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,04367618 0,111335 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,04367618 0,11118122 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,04367618 0,11102787 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,04367618 0,11087494 ! regulation of organ growth GO:0046620 6 6 0,000 0,04367618 0,11072243 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,04367618 0,11057034 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,04367618 0,11041866 ! response to dsRNA GO:0043331 6 6 0,000 0,04367618 0,11026741 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,04367618 0,11011656 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,04367618 0,10996613 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 0,04367618 0,10981611 ! genitalia development GO:0048806 6 6 0,000 0,04367618 0,10966649 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,04367618 0,10951729 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,04367618 0,10936849 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 0,04367618 0,10922009 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,04367618 0,10907209 ! multicellular organismal aging GO:0010259 6 6 0,000 0,04367618 0,1089245 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,04367618 0,10877731 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,04367618 0,10863051 ! erythrocyte development GO:0048821 6 6 0,000 0,04367618 0,1084841 ! renal water homeostasis GO:0003091 6 6 0,000 0,04367618 0,1083381 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,04367618 0,10819248 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,04367618 0,10804726 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,04367618 0,10790242 ! ribosome assembly GO:0042255 6 6 0,000 0,04367618 0,10775797 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,04367618 0,10761391 ! diencephalon development GO:0021536 6 6 0,000 0,04367618 0,10747023 ! fucose catabolic process GO:0019317 6 6 0,000 0,04367618 0,10732694 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,04367618 0,10718403 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,04367618 0,1070415 ! regulation of lipid transport GO:0032368 6 6 0,000 0,04367618 0,10689934 ! regulation of cell division GO:0051302 6 6 0,000 0,04367618 0,10675757 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,04367618 0,10661617 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,04367618 0,10647514 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,04367618 0,10633449 ! neuroblast proliferation GO:0007405 6 6 0,000 0,04367618 0,1061942 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,04367618 0,10605429 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,04367618 0,10591474 ! regulation of glucose transport GO:0010827 6 6 0,000 0,04367618 0,10577557 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,04367618 0,10563675 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,04367618 0,1054983 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,04367618 0,10536022 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,04367618 0,10522249 ! thymus development GO:0048538 6 6 0,000 0,04367618 0,10508512 ! lymph node development GO:0048535 6 6 0,000 0,04367618 0,10494812 ! organic cation transport GO:0015695 6 6 0,000 0,04367618 0,10481147 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,04367618 0,10467517 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,04367618 0,10453923 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,04367618 0,10440364 ! sperm-egg recognition GO:0035036 7 6 0,000 0,04367618 0,1042684 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,04367618 0,10413351 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,04367618 0,10399897 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,04367618 0,10386478 ! alditol metabolic process GO:0019400 6 6 0,000 0,04367618 0,10373094 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,04367618 0,10359743 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,04367618 0,10346427 ! maternal placenta development GO:0001893 6 6 0,000 0,04367618 0,10333146 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,04367618 0,10319898 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 1,000 0,04532868 0,10696641 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 0,04532868 0,10682962 ! positive regulation of ligase activity GO:0051351 47 46 1,000 0,04532868 0,10669319 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 1,000 0,04712344 0,11077616 ! sex differentiation GO:0007548 47 47 1,000 0,04712344 0,11063504 ! amine transport GO:0015837 47 47 1,000 0,04712344 0,11049428 ! actin filament organization GO:0007015 50 48 1,000 0,04894407 0,11461743 ! protein localization in nucleus GO:0034504 48 48 1,000 0,04894407 0,11447198 ! DNA recombination GO:0006310 48 48 1,000 0,04894407 0,11432689 ! respiratory burst GO:0045730 7 7 0,000 0,0507714 0,11844518 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,0507714 0,11829543 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,0507714 0,11814607 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,0507714 0,11799709 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,0507714 0,11784847 ! regulation of chemokine production GO:0032642 7 7 0,000 0,0507714 0,11770024 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,0507714 0,11755237 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,0507714 0,11740488 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,0507714 0,11725776 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,0507714 0,117111 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,0507714 0,11696461 ! gene silencing by RNA GO:0031047 7 7 0,000 0,0507714 0,11681859 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,0507714 0,11667293 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,0507714 0,11652763 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,0507714 0,1163827 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,0507714 0,11623812 ! axis specification GO:0009798 7 7 0,000 0,0507714 0,11609391 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,0507714 0,11595005 ! visual behavior GO:0007632 7 7 0,000 0,0507714 0,11580655 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,0507714 0,1156634 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,0507714 0,1155206 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,0507714 0,11537816 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,0507714 0,11523607 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,0507714 0,11509433 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,0507714 0,11495293 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,0507714 0,11481189 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,0507714 0,11467119 ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,0507714 0,11453083 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,0507714 0,11439082 ! protein targeting to ER GO:0045047 8 7 0,000 0,0507714 0,11425115 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,0507714 0,11411182 ! endoderm development GO:0007492 7 7 0,000 0,0507714 0,11397282 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,0507714 0,11383417 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,0507714 0,11369586 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,0507714 0,11355787 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,0507714 0,11342023 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,0507714 0,11328292 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,0507714 0,11314594 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 0,0507714 0,11300929 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,0507714 0,11287297 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,0507714 0,11273697 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,0507714 0,11260131 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,0507714 0,11246597 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,0507714 0,11233096 ! response to X-ray GO:0010165 7 7 0,000 0,0507714 0,11219627 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,0507714 0,1120619 ! UV protection GO:0009650 7 7 0,000 0,0507714 0,11192786 ! DNA integration GO:0015074 7 7 0,000 0,0507714 0,11179413 ! myofibril assembly GO:0030239 7 7 0,000 0,0507714 0,11166073 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,0507714 0,11152764 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,0507714 0,11139487 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,0507714 0,11126241 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,0507714 0,11113027 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,0507714 0,11099844 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,0507714 0,11086693 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,0507714 0,11073573 GO:0019827|stem cell maintenance, ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,0507714 0,11060483 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,0507714 0,11047425 ! axon cargo transport GO:0008088 7 7 0,000 0,0507714 0,11034397 ! eating behavior GO:0042755 7 7 0,000 0,0507714 0,110214 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,0507714 0,11008434 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,0507714 0,10995498 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,0507714 0,10982593 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,0507714 0,10969717 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,0507714 0,10956872 ! induction of an organ GO:0001759 7 7 0,000 0,0507714 0,10944057 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,0507714 0,10931272 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,0507714 0,10918517 ! autonomic nervous system development GO:0048483 7 7 0,000 0,0507714 0,10905791 ! intracellular lipid transport GO:0032365 7 7 0,000 0,0507714 0,10893095 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,0507714 0,10880429 ! platelet activation GO:0030168 8 7 0,000 0,0507714 0,10867792 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,0507714 0,10855184 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,0507714 0,10842606 ! natural killer cell activation GO:0030101 7 7 0,000 0,0507714 0,10830057 ! response to gamma radiation GO:0010332 8 7 0,000 0,0507714 0,10817536 ! NADP metabolic process GO:0006739 7 7 0,000 0,0507714 0,10805045 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,0507714 0,10792582 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,0507714 0,10780148 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,0507714 0,10767743 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,0507714 0,10755367 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,0507714 0,10743018 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,0507714 0,10730698 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,0507714 0,10718407 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,0507714 0,10706143 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,0507714 0,10693907 ! cell-cell recognition GO:0009988 8 7 0,000 0,0507714 0,106817 ! hormone catabolic process GO:0042447 7 7 0,000 0,0507714 0,1066952 ! dopamine metabolic process GO:0042417 7 7 0,000 0,0507714 0,10657368 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,0507714 0,10645243 ! oxygen transport GO:0015671 7 7 0,000 0,0507714 0,10633146 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,0507714 0,10621077 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,0507714 0,10609035 ! regulation of axon extension GO:0030516 7 7 0,000 0,0507714 0,1059702 ! cell killing GO:0001906 7 7 0,000 0,0507714 0,10585033 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,0507714 0,10573072 ! adult feeding behavior GO:0008343 7 7 0,000 0,0507714 0,10561139 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,0507714 0,10549232 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,0507714 0,10537352 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,0507714 0,10525499 ! negative regulation of T cell activation GO:0050868 7 7 0,000 0,0507714 0,10513673 ! response to cold GO:0009409 7 7 0,000 0,0507714 0,10501873 ! leukocyte differentiation GO:0002521 50 49 1,000 0,0507901 0,10493963 ! cell cycle arrest GO:0007050 49 49 1,000 0,0507901 0,10482211 ! cellular lipid catabolic process GO:0044242 50 49 1,000 0,0507901 0,10470486 ! skeletal muscle tissue development GO:0007519 50 49 1,000 0,0507901 0,10458787 GO:0060538|skeletal muscle organ development, ! cofactor biosynthetic process GO:0051188 49 49 1,000 0,0507901 0,10447114 ! positive regulation of cell activation GO:0050867 49 49 1,000 0,0507901 0,10435468 GO:0002696|positive regulation of leukocyte activation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,05266106 0,10807833 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,05266106 0,10795811 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,05455652 0,11171962 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,05647601 0,11552196 ! cell fate commitment GO:0045165 52 52 1,000 0,05647601 0,11539388 ! regulation of body fluid levels GO:0050878 55 52 1,000 0,05647601 0,11526609 ! response to light stimulus GO:0009416 53 52 1,000 0,05647601 0,11513859 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,057815 0,11773817 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,057815 0,11760821 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,057815 0,11747855 ! positive regulation of translation GO:0045727 8 8 0,000 0,057815 0,11734917 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,057815 0,11722007 ! superoxide anion generation GO:0042554 8 8 0,000 0,057815 0,11709126 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,057815 0,11696272 ! cGMP metabolic process GO:0046068 8 8 0,000 0,057815 0,11683448 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,057815 0,11670651 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,057815 0,11657882 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,057815 0,11645141 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,057815 0,11632428 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,057815 0,11619743 ! zinc ion transport GO:0006829 8 8 0,000 0,057815 0,11607085 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,057815 0,11594455 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,057815 0,11581852 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,057815 0,11569277 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,057815 0,11556729 ! lipid localization GO:0010876 8 8 0,000 0,057815 0,11544208 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,057815 0,11531715 ! response to cAMP GO:0051591 8 8 0,000 0,057815 0,11519248 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,057815 0,11506808 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,057815 0,11494395 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,057815 0,11482009 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,057815 0,11469649 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,057815 0,11457316 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,057815 0,1144501 ! sensory perception of taste GO:0050909 8 8 0,000 0,057815 0,1143273 ! organelle fusion GO:0048284 8 8 0,000 0,057815 0,11420476 ! pancreas development GO:0031016 8 8 0,000 0,057815 0,11408249 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,057815 0,11396047 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,057815 0,11383872 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,057815 0,11371723 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,057815 0,11359599 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,057815 0,11347502 ! sperm motility GO:0030317 8 8 0,000 0,057815 0,1133543 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,057815 0,11323384 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,057815 0,11311363 GO:0032392|DNA geometric change, ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,057815 0,11299368 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,057815 0,11287399 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,057815 0,11275454 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,057815 0,11263535 ! Golgi organization GO:0007030 8 8 0,000 0,057815 0,11251641 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,057815 0,11239772 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,057815 0,11227929 ! fructose metabolic process GO:0006000 8 8 0,000 0,057815 0,1121611 ! mannose metabolic process GO:0006013 9 8 0,000 0,057815 0,11204316 ! NAD metabolic process GO:0019674 8 8 0,000 0,057815 0,11192546 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,057815 0,11180802 ! plasma membrane fusion GO:0045026 8 8 0,000 0,057815 0,11169082 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,057815 0,11157387 ! response to fungus GO:0009620 8 8 0,000 0,057815 0,11145716 ! stem cell differentiation GO:0048863 8 8 0,000 0,057815 0,11134069 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,057815 0,11122447 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,057815 0,11110849 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,057815 0,11099275 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,057815 0,11087726 ! regulation of vasodilation GO:0042312 8 8 0,000 0,057815 0,110762 ! vasoconstriction GO:0042310 8 8 0,000 0,057815 0,11064698 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,057815 0,1105322 ! muscle cell development GO:0055001 8 8 0,000 0,057815 0,11041766 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,057815 0,11030336 ! sensory perception of pain GO:0019233 8 8 0,000 0,057815 0,11018929 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,057815 0,11007546 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,057815 0,10996186 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,057815 0,1098485 ! chromatin silencing GO:0006342 8 8 0,000 0,057815 0,10973537 ! tissue regeneration GO:0042246 8 8 0,000 0,057815 0,10962247 ! salivary gland development GO:0007431 8 8 0,000 0,057815 0,10950981 ! T cell homeostasis GO:0043029 8 8 0,000 0,057815 0,10939737 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,057815 0,10928517 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,057815 0,1091732 ! water homeostasis GO:0030104 8 8 0,000 0,057815 0,10906146 ! cofactor transport GO:0051181 8 8 0,000 0,057815 0,10894994 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,057815 0,10883865 ! acid secretion GO:0046717 8 8 0,000 0,057815 0,10872759 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,057815 0,10861676 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,057815 0,10850615 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,057815 0,10839577 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,057815 0,10828561 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,057815 0,10817568 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,057815 0,10806597 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 0,057815 0,10795648 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,057815 0,10784721 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,057815 0,10773816 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,057815 0,10762934 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,057815 0,10752073 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,057815 0,10741234 ! developmental induction GO:0031128 8 8 0,000 0,057815 0,10730417 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,057815 0,10719622 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,057815 0,10708848 ! actin filament polymerization GO:0030041 9 8 0,000 0,057815 0,10698097 ! peptide hormone processing GO:0016486 8 8 0,000 0,057815 0,10687366 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,057815 0,10676658 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,057815 0,1066597 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 1,000 0,05841909 0,10766638 ! regulation of T cell activation GO:0050863 53 53 1,000 0,05841909 0,10755882 ! response to virus GO:0009615 54 54 1,000 0,06038533 0,11106802 ! hormone metabolic process GO:0042445 55 54 1,000 0,06038533 0,11095728 ! in utero embryonic development GO:0001701 55 55 1,000 0,06237428 0,1144978 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,06237428 0,11438388 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,06237428 0,11427017 ! lactation GO:0007595 10 9 0,000 0,06480735 0,11860968 ! embryonic pattern specification GO:0009880 10 9 0,000 0,06480735 0,11849201 ! positive regulation of cell size GO:0045793 9 9 0,000 0,06480735 0,11837457 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,06480735 0,11825737 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,06480735 0,1181404 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,06480735 0,11802366 ! viral genome replication GO:0019079 9 9 0,000 0,06480735 0,11790715 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,06480735 0,11779087 ! copper ion transport GO:0006825 9 9 0,000 0,06480735 0,11767482 ! lipid phosphorylation GO:0046834 9 9 0,000 0,06480735 0,117559 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,06480735 0,11744341 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,06480735 0,11732804 ! RNA polyadenylation GO:0043631 9 9 0,000 0,06480735 0,1172129 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,06480735 0,11709799 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,06480735 0,1169833 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,06480735 0,11686883 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,06480735 0,11675459 ! phospholipid efflux GO:0033700 9 9 0,000 0,06480735 0,11664057 ! response to alkaloid GO:0043279 10 9 0,000 0,06480735 0,11652678 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,06480735 0,1164132 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,06480735 0,11629985 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,06480735 0,11618672 ! response to ethanol GO:0045471 9 9 0,000 0,06480735 0,1160738 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,06480735 0,11596111 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,06480735 0,11584864 ! methionine metabolic process GO:0006555 9 9 0,000 0,06480735 0,11573638 ! glutamine metabolic process GO:0006541 9 9 0,000 0,06480735 0,11562434 ! cerebral cortex development GO:0021987 9 9 0,000 0,06480735 0,11551252 ! pigmentation during development GO:0048066 9 9 0,000 0,06480735 0,11540091 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,06480735 0,11528952 ! central nervous system neuron development GO:0021954 10 9 0,000 0,06480735 0,11517835 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,06480735 0,11506738 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,06480735 0,11495664 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,06480735 0,1148461 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,06480735 0,11473578 ! peptide secretion GO:0002790 9 9 0,000 0,06480735 0,11462567 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,06480735 0,11451577 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,06480735 0,11440608 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,06480735 0,1142966 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,06480735 0,11418733 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,06480735 0,11407827 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,06480735 0,11396941 ! DNA replication initiation GO:0006270 9 9 0,000 0,06480735 0,11386077 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,06480735 0,11375233 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,06480735 0,1136441 ! regulation of cellular pH GO:0030641 9 9 0,000 0,06480735 0,11353607 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,06480735 0,11342825 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,06480735 0,11332063 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,06480735 0,11321322 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,06480735 0,11310601 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,06480735 0,112999 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,06480735 0,1128922 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,06480735 0,11278559 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,06480735 0,11267919 ! collagen catabolic process GO:0030574 9 9 0,000 0,06480735 0,11257299 ! purine base metabolic process GO:0006144 9 9 0,000 0,06480735 0,11246699 ! gas transport GO:0015669 9 9 0,000 0,06480735 0,11236119 ! cholesterol efflux GO:0033344 9 9 0,000 0,06480735 0,11225559 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,06480735 0,11215018 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,06480735 0,11204498 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,06480735 0,11193997 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,06480735 0,11183515 ! defense response to virus GO:0051607 9 9 0,000 0,06480735 0,11173054 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,06480735 0,11162612 ! actin filament-based movement GO:0030048 9 9 0,000 0,06480735 0,11152189 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,06480735 0,11141786 ! carboxylic acid transport GO:0046942 59 59 1,000 0,07054875 0,12117553 GO:0015849|organic acid transport, ! protein localization in organelle GO:0033365 59 59 1,000 0,07054875 0,12106271 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,07174882 0,12300751 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,07174882 0,12289319 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,07174882 0,12277908 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,07174882 0,12266519 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,07174882 0,1225515 ! neuron maturation GO:0042551 10 10 0,000 0,07174882 0,12243803 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,07174882 0,12232476 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,07174882 0,12221171 ! hormone secretion GO:0046879 10 10 0,000 0,07174882 0,12209886 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,07174882 0,12198623 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,07174882 0,1218738 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,07174882 0,12176157 ! cAMP metabolic process GO:0046058 10 10 0,000 0,07174882 0,12164956 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,07174882 0,12153775 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,07174882 0,12142614 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,07174882 0,12131474 ! glial cell development GO:0021782 10 10 0,000 0,07174882 0,12120355 ! phototransduction GO:0007602 11 10 0,000 0,07174882 0,12109256 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,07174882 0,12098177 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,07174882 0,12087118 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,07174882 0,12076079 ! fat cell differentiation GO:0045444 10 10 0,000 0,07174882 0,12065061 ! myoblast differentiation GO:0045445 10 10 0,000 0,07174882 0,12054063 ! centrosome cycle GO:0007098 10 10 0,000 0,07174882 0,12043085 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,07174882 0,12032126 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,07174882 0,12021188 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,07174882 0,1201027 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,07174882 0,11999371 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,07174882 0,11988492 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,07174882 0,11977633 ! protein polyubiquitination GO:0000209 10 10 0,000 0,07174882 0,11966794 ! glutamate metabolic process GO:0006536 11 10 0,000 0,07174882 0,11955974 ! plasma membrane organization GO:0007009 10 10 0,000 0,07174882 0,11945173 ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,07174882 0,11934393 ! lysosomal transport GO:0007041 10 10 0,000 0,07174882 0,11923631 ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,07174882 0,11912889 ! vesicle coating GO:0006901 10 10 0,000 0,07174882 0,11902167 ! exocrine system development GO:0035272 10 10 0,000 0,07174882 0,11891463 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,07174882 0,11880779 ! neuromuscular junction development GO:0007528 10 10 0,000 0,07174882 0,11870114 ! embryo implantation GO:0007566 11 10 0,000 0,07174882 0,11859468 ! regulation of protein binding GO:0043393 11 10 0,000 0,07174882 0,11848841 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,07174882 0,11838234 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,07174882 0,11827645 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,07174882 0,11817075 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,07174882 0,11806524 ! protein export from nucleus GO:0006611 10 10 0,000 0,07174882 0,11795992 ! negative regulation of immune response GO:0050777 10 10 0,000 0,07174882 0,11785479 ! cytolysis GO:0019835 10 10 0,000 0,07174882 0,11774984 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,07174882 0,11764508 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,07174882 0,11754051 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,07174882 0,11743612 ! histone deacetylation GO:0016575 10 10 0,000 0,07174882 0,11733192 ! mRNA splice site selection GO:0006376 11 10 0,000 0,07174882 0,1172279 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,07174882 0,11712407 ! gland morphogenesis GO:0022612 10 10 0,000 0,07174882 0,11702042 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,07174882 0,11691695 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,07174882 0,11681367 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,07174882 0,11671057 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,07174882 0,11660765 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,07174882 0,11650491 ! regulation of epidermis development GO:0045682 10 10 0,000 0,07174882 0,11640235 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,07174882 0,11629997 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,07174882 0,11619778 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,07174882 0,11609576 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,07174882 0,11599392 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,07174882 0,11589226 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,07174882 0,11579078 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,07174882 0,11568948 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,07174882 0,11558835 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,07174882 0,1154874 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,07174882 0,11538662 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,07264495 0,11672593 ! axonogenesis GO:0007409 66 62 1,000 0,07689758 0,12345142 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,07689758 0,12334398 ! protein import GO:0017038 62 62 1,000 0,07689758 0,12323673 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,07689758 0,12312966 ! protein secretion GO:0009306 11 11 0,000 0,07863976 0,12580997 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,07863976 0,12570086 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,07863976 0,12559193 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,07863976 0,12548319 ! negative regulation of defense response GO:0031348 11 11 0,000 0,07863976 0,12537464 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,07863976 0,12526628 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,07863976 0,12515811 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,07863976 0,12505012 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,07863976 0,12494232 ! skin development GO:0043588 11 11 0,000 0,07863976 0,1248347 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,07863976 0,12472727 ! microtubule-based transport GO:0010970 11 11 0,000 0,07863976 0,12462002 ! endothelial cell migration GO:0043542 11 11 0,000 0,07863976 0,12451296 ! peroxisomal transport GO:0043574 11 11 0,000 0,07863976 0,12440608 ! protein amino acid methylation GO:0006479 11 11 0,000 0,07863976 0,12429939 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,07863976 0,12419288 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,07863976 0,12408655 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,07863976 0,1239804 ! T cell proliferation GO:0042098 11 11 0,000 0,07863976 0,12387443 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,07863976 0,12376865 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,07863976 0,12366304 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,07863976 0,12355762 ! smooth muscle contraction GO:0006939 11 11 0,000 0,07863976 0,12345237 ! cellular response to starvation GO:0009267 11 11 0,000 0,07863976 0,12334731 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,07863976 0,12324242 ! digestive system process GO:0022600 11 11 0,000 0,07863976 0,12313771 ! mitotic spindle organization GO:0007052 11 11 0,000 0,07863976 0,12303318 ! fucose metabolic process GO:0006004 11 11 0,000 0,07863976 0,12292883 ! membrane budding GO:0006900 11 11 0,000 0,07863976 0,12282465 ! monoamine transport GO:0015844 11 11 0,000 0,07863976 0,12272065 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,07863976 0,12261682 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,07863976 0,12251318 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,07863976 0,1224097 ! body fluid secretion GO:0007589 11 11 0,000 0,07863976 0,1223064 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,07863976 0,12220328 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,07863976 0,12210033 ! intermediate filament-based process GO:0045103 11 11 0,000 0,07863976 0,12199755 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,07863976 0,12189494 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,07863976 0,12179251 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,07863976 0,12169025 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,07863976 0,12158816 ! oogenesis GO:0048477 11 11 0,000 0,07863976 0,12148624 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,07863976 0,12138449 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,07863976 0,12128292 ! vitamin transport GO:0051180 11 11 0,000 0,07863976 0,12118151 ! muscle maintenance GO:0046716 12 11 0,000 0,07863976 0,12108027 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,07863976 0,1209792 ! hindbrain development GO:0030902 11 11 0,000 0,07863976 0,1208783 ! steroid catabolic process GO:0006706 11 11 0,000 0,07863976 0,12077757 ! endocrine process GO:0050886 11 11 0,000 0,07863976 0,12067701 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,07863976 0,12057661 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,07863976 0,12047638 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,07863976 0,12037632 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,07905321 0,12090877 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 1,000 0,07905321 0,12080852 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,08122787 0,12402897 ! anion transport GO:0006820 65 65 1,000 0,08342117 0,12727253 ! regulation of hormone levels GO:0010817 66 65 1,000 0,08342117 0,12716726 ! translational initiation GO:0006413 12 12 0,000 0,08548055 0,13019889 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,08548055 0,13009138 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,08548055 0,12998404 ! initiation of viral infection GO:0019059 12 12 0,000 0,08548055 0,12987688 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,08548055 0,1297699 ! iron ion transport GO:0006826 13 12 0,000 0,08548055 0,12966309 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,08548055 0,12955646 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,08548055 0,12945001 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,08548055 0,12934373 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,08548055 0,12923762 ! collagen metabolic process GO:0032963 12 12 0,000 0,08548055 0,12913169 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,08548055 0,12902593 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,08548055 0,12892034 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,08548055 0,12881493 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,08548055 0,12870969 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,08548055 0,12860462 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,08548055 0,12849972 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,08548055 0,12839499 ! actomyosin structure organization GO:0031032 12 12 0,000 0,08548055 0,12829044 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,08548055 0,12818605 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,08548055 0,12808184 ! retinoid metabolic process GO:0001523 12 12 0,000 0,08548055 0,12797779 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,08548055 0,12787391 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,08548055 0,1277702 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,08548055 0,12766666 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,08548055 0,12756329 ! acute-phase response GO:0006953 12 12 0,000 0,08548055 0,12746008 ! vacuolar transport GO:0007034 12 12 0,000 0,08548055 0,12735704 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,08548055 0,12725417 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,08548055 0,12715146 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,08548055 0,12704892 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,08548055 0,12694654 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,08548055 0,12684433 ! male gonad development GO:0008584 12 12 0,000 0,08548055 0,12674228 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,08548055 0,1266404 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,08548055 0,12653868 ! renal system process GO:0003014 12 12 0,000 0,08548055 0,12643713 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,08548055 0,12633573 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,08548055 0,1262345 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,08548055 0,12613343 ! pallium development GO:0021543 13 12 0,000 0,08548055 0,12603253 ! cell fate determination GO:0001709 12 12 0,000 0,08548055 0,12593178 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,08548055 0,1258312 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,08548055 0,12573077 ! G1 phase GO:0051318 13 12 0,000 0,08548055 0,12563051 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,08548055 0,12553041 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,08548055 0,12543046 ! detection of light stimulus GO:0009583 13 12 0,000 0,08548055 0,12533068 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,08548055 0,12523105 ! hormone transport GO:0009914 12 12 0,000 0,08548055 0,12513158 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,08548055 0,12503227 ! heme biosynthetic process GO:0006783 12 12 0,000 0,08548055 0,12493312 ! spermatid differentiation GO:0048515 13 12 0,000 0,08548055 0,12483412 GO:0007286|spermatid development, ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,08548055 0,12473528 ! neural tube closure GO:0001843 13 12 0,000 0,08548055 0,1246366 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,08548055 0,12453807 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,08548055 0,1244397 ! nucleoside triphosphate metabolic process GO:0009141 66 66 1,000 0,08563272 0,12456283 ! DNA packaging GO:0006323 66 66 1,000 0,08563272 0,1244646 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,08786215 0,12760437 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! striated muscle tissue development GO:0014706 69 67 1,000 0,08786215 0,12750389 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,08786215 0,12740357 ! response to radiation GO:0009314 70 68 1,000 0,09010908 0,13055899 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 1,000 0,09010908 0,13045643 ! regulation of cell size GO:0008361 68 68 1,000 0,09010908 0,13035403 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,09227154 0,1333776 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,09227154 0,13327308 ! phenol metabolic process GO:0018958 13 13 0,000 0,09227154 0,13316871 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,09227154 0,13306451 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,09227154 0,13296047 ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,09227154 0,1328566 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,09227154 0,13275289 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,09227154 0,13264933 ! regeneration GO:0031099 13 13 0,000 0,09227154 0,13254594 ! keratinization GO:0031424 13 13 0,000 0,09227154 0,13244271 ! post-embryonic development GO:0009791 14 13 0,000 0,09227154 0,13233965 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,09227154 0,13223674 ! patterning of blood vessels GO:0001569 13 13 0,000 0,09227154 0,13213399 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,09227154 0,1320314 ! regulation of innate immune response GO:0045088 13 13 0,000 0,09227154 0,13192897 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,09227154 0,1318267 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,09227154 0,13172459 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,09227154 0,13162264 ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,09227154 0,13152084 ! autophagy GO:0006914 13 13 0,000 0,09227154 0,1314192 ! actin filament bundle formation GO:0051017 13 13 0,000 0,09227154 0,13131772 ! cell aging GO:0007569 13 13 0,000 0,09227154 0,13121639 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,09227154 0,13111522 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,09227154 0,13101421 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,09227154 0,13091335 ! regulation of peptide secretion GO:0002791 13 13 0,000 0,09227154 0,13081265 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,09227154 0,1307121 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,09227154 0,13061171 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,09227154 0,13051147 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,09227154 0,13041138 ! vasodilation GO:0042311 14 13 0,000 0,09227154 0,13031145 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,09227154 0,13021167 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,09227154 0,13011205 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,09227154 0,13001257 GO:0006664|glycolipid metabolic process, ! neural crest cell migration GO:0001755 14 13 0,000 0,09227154 0,12991325 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,09227154 0,12981408 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,09227154 0,12971506 ! immunoglobulin production GO:0002377 13 13 0,000 0,09227154 0,12961619 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,09227154 0,12951748 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,09227154 0,12941891 ! cell-cell junction organization GO:0045216 13 13 0,000 0,09227154 0,12932049 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,09227154 0,12922222 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,09227154 0,1291241 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,09227154 0,12902614 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,09227154 0,12892831 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,09227154 0,12883064 GO:0019370|leukotriene biosynthetic process, ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,09227154 0,12873312 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,09227154 0,12863574 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,09227154 0,12853851 ! telomere organization GO:0032200 13 13 0,000 0,09227154 0,12844142 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,09227154 0,12834449 ! regulation of amine transport GO:0051952 13 13 0,000 0,09227154 0,1282477 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,09227154 0,12815105 ! regulation of translation GO:0006417 69 69 1,000 0,09237314 0,12819555 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,09237314 0,12809909 ! cell part morphogenesis GO:0032990 75 70 1,000 0,09465397 0,13116335 ! wound healing GO:0042060 74 70 1,000 0,09465397 0,13106481 ! muscle tissue development GO:0060537 72 70 1,000 0,09465397 0,13096641 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,09901308 0,13689505 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,09901308 0,13679243 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,09901308 0,13668996 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,09901308 0,13658765 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,09901308 0,13648549 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,09901308 0,13638349 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,09901308 0,13628163 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,09901308 0,13617993 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,09901308 0,13607838 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,09901308 0,13597698 ! vesicle docking GO:0048278 14 14 0,000 0,09901308 0,13587573 ! superoxide metabolic process GO:0006801 15 14 0,000 0,09901308 0,13577463 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,09901308 0,13567368 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,09901308 0,13557288 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,09901308 0,13547224 ! hair cycle GO:0042633 14 14 0,000 0,09901308 0,13537174 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,09901308 0,13527139 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,09901308 0,13517119 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,09901308 0,13507113 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,09901308 0,13497123 ! lysosome organization GO:0007040 14 14 0,000 0,09901308 0,13487147 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,09901308 0,13477186 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,09901308 0,1346724 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,09901308 0,13457308 ! primary neural tube formation GO:0014020 15 14 0,000 0,09901308 0,13447392 ! peptide cross-linking GO:0018149 14 14 0,000 0,09901308 0,13437489 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,09901308 0,13427601 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,09901308 0,13417728 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,09901308 0,13407869 ! formation of primary germ layer GO:0001704 14 14 0,000 0,09901308 0,13398025 GO:0001707|mesoderm formation, ! collagen fibril organization GO:0030199 14 14 0,000 0,09901308 0,13388195 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,09901308 0,1337838 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,09901308 0,13368579 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,09901308 0,13358792 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,09901308 0,1334902 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,09901308 0,13339262 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,09901308 0,13329518 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,09901308 0,13319789 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,09901308 0,13310073 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,09926449 0,13334143 ! sensory organ development GO:0007423 72 72 1,000 0,09926449 0,13324432 ! regulation of cytokine production GO:0001817 72 72 1,000 0,09926449 0,13314734 ! coenzyme metabolic process GO:0006732 75 74 1,000 0,1039378 0,13931445 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,10570552 0,14158087 ! positive regulation of ossification GO:0045778 15 15 0,000 0,10570552 0,14147805 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,10570552 0,14137539 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,10570552 0,14127287 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,10570552 0,14117049 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,10570552 0,14106827 ! response to vitamin GO:0033273 15 15 0,000 0,10570552 0,14096619 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,10570552 0,14086427 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,10570552 0,14076249 ! ovarian follicle development GO:0001541 15 15 0,000 0,10570552 0,14066085 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,10570552 0,14055937 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,10570552 0,14045803 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,10570552 0,14035683 ! heme metabolic process GO:0042168 15 15 0,000 0,10570552 0,14025578 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,10570552 0,14015488 ! response to starvation GO:0042594 15 15 0,000 0,10570552 0,14005412 ! response to ionizing radiation GO:0010212 16 15 0,000 0,10570552 0,13995351 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,10570552 0,13985304 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,10570552 0,13975271 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,10570552 0,13965253 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,10570552 0,13955249 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,10570552 0,1394526 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,10570552 0,13935285 ! phospholipid transport GO:0015914 15 15 0,000 0,10570552 0,13925324 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,10570552 0,13915377 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,10570552 0,13905445 ! glutathione metabolic process GO:0006749 16 15 0,000 0,10570552 0,13895526 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,10570552 0,13885622 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,10570552 0,13875732 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,10570552 0,13865856 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,10570552 0,13855994 ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,10570552 0,13846146 ! protein homooligomerization GO:0051260 15 15 0,000 0,10570552 0,13836313 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,10570552 0,13826493 ! ribonucleotide biosynthetic process GO:0009260 75 75 1,000 0,10629713 0,13894016 ! purine ribonucleotide metabolic process GO:0009150 75 75 1,000 0,10629713 0,13884169 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,11105946 0,14495934 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,11234923 0,14653901 ! alkaloid metabolic process GO:0009820 16 16 0,000 0,11234923 0,14643538 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,11234923 0,14633189 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,11234923 0,14622855 ! learning GO:0007612 16 16 0,000 0,11234923 0,14612535 ! circadian rhythm GO:0007623 16 16 0,000 0,11234923 0,1460223 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,11234923 0,1459194 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,11234923 0,14581664 ! vacuole organization GO:0007033 16 16 0,000 0,11234923 0,14571402 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,11234923 0,14561155 ! vesicle targeting GO:0006903 17 16 0,000 0,11234923 0,14550922 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,11234923 0,14540704 ! iron ion homeostasis GO:0055072 16 16 0,000 0,11234923 0,145305 ! positive regulation of cell development GO:0010720 16 16 0,000 0,11234923 0,1452031 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,11234923 0,14510135 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,11234923 0,14499974 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,11234923 0,14489827 ! fatty acid transport GO:0015908 16 16 0,000 0,11234923 0,14479694 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,11234923 0,14469575 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,11234923 0,14459471 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,11234923 0,14449381 ! cofactor catabolic process GO:0051187 16 16 0,000 0,11234923 0,14439304 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,11234923 0,14429242 ! polyol metabolic process GO:0019751 16 16 0,000 0,11234923 0,14419194 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,11234923 0,1440916 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,11234923 0,14399139 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,11234923 0,14389133 GO:0001841|neural tube formation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,11234923 0,14379141 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,11234923 0,14369162 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,11346179 0,14501392 ! nuclear transport GO:0051169 79 79 1,000 0,11587778 0,14799914 GO:0006913|nucleocytoplasmic transport, ! neuron projection development GO:0031175 85 80 1,000 0,11830712 0,15099725 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,11894453 0,15170573 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,11894453 0,15160081 ! positive regulation of cell adhesion GO:0045785 17 17 0,000 0,11894453 0,15149604 ! myelination GO:0042552 17 17 0,000 0,11894453 0,15139142 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,11894453 0,15128694 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,11894453 0,1511826 ! leukocyte adhesion GO:0007159 17 17 0,000 0,11894453 0,15107841 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,11894453 0,15097436 ! sensory perception of smell GO:0007608 17 17 0,000 0,11894453 0,15087046 ! glucose transport GO:0015758 17 17 0,000 0,11894453 0,1507667 ! cell junction assembly GO:0034329 18 17 0,000 0,11894453 0,15066308 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,11894453 0,1505596 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,11894453 0,15045626 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,11894453 0,15035307 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,11894453 0,15025002 ! neural crest cell development GO:0014032 19 17 0,000 0,11894453 0,15014711 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,11894453 0,15004434 ! negative regulation of cell development GO:0010721 18 17 0,000 0,11894453 0,14994171 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,11894453 0,14983922 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,11894453 0,14973687 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,11894453 0,14963466 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,11894453 0,14953259 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,11894453 0,14943066 ! pigmentation GO:0043473 17 17 0,000 0,11894453 0,14932887 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,11894453 0,14922721 ! adult locomotory behavior GO:0008344 17 17 0,000 0,11894453 0,1491257 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,11894453 0,14902432 ! gene silencing GO:0016458 17 17 0,000 0,11894453 0,14892308 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,12549179 0,15701383 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,12549179 0,15690731 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,12549179 0,15680093 ! membrane docking GO:0022406 18 18 0,000 0,12549179 0,1566947 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,12549179 0,15658861 GO:0070661|leukocyte proliferation, ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,12549179 0,15648266 ! hexose transport GO:0008645 18 18 0,000 0,12549179 0,15637686 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,12549179 0,1562712 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,12549179 0,15616568 ! striated muscle contraction GO:0006941 18 18 0,000 0,12549179 0,1560603 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,12549179 0,15595507 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,12549179 0,15584998 GO:0046519|sphingoid metabolic process, ! hexose biosynthetic process GO:0019319 18 18 0,000 0,12549179 0,15574503 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,12549179 0,15564022 ! B cell differentiation GO:0030183 18 18 0,000 0,12549179 0,15553556 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,12549179 0,15543103 ! ensheathment of neurons GO:0007272 18 18 0,000 0,12549179 0,15532664 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,12549179 0,1552224 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,12549179 0,15511829 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,12549179 0,15501432 ! ribonucleotide metabolic process GO:0009259 83 83 1,000 0,12567202 0,15513298 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 0,1306429 0,16116123 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,13199134 0,16271575 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,13199134 0,16260698 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,13199134 0,16249836 ! glial cell differentiation GO:0010001 19 19 0,000 0,13199134 0,16238988 ! regulation of pH GO:0006885 19 19 0,000 0,13199134 0,16228155 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,13199134 0,16217336 ! feeding behavior GO:0007631 19 19 0,000 0,13199134 0,16206532 ! peroxisome organization GO:0007031 19 19 0,000 0,13199134 0,16195742 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,13199134 0,16184966 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,13199134 0,16174205 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,13199134 0,16163458 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,13199134 0,16152725 ! peripheral nervous system development GO:0007422 19 19 0,000 0,13199134 0,16142007 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,13199134 0,16131303 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,13199134 0,16120613 ! response to heat GO:0009408 19 19 0,000 0,13199134 0,16109937 ! vesicle localization GO:0051648 20 19 0,000 0,13199134 0,16099275 ! purine nucleotide biosynthetic process GO:0006164 88 88 1,000 0,13818459 0,16843531 ! regulation of muscle development GO:0048634 21 20 0,000 0,13844353 0,16863941 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,13844353 0,16852802 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,13844353 0,16841678 ! organic ether metabolic process GO:0018904 20 20 0,000 0,13844353 0,16830569 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,13844353 0,16819474 ! phagocytosis GO:0006909 21 20 0,000 0,13844353 0,16808394 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,13844353 0,16797329 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,13844353 0,16786278 ! protein targeting to membrane GO:0006612 22 20 0,000 0,13844353 0,16775241 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,13844353 0,1676422 ! chromatin remodeling GO:0006338 20 20 0,000 0,13844353 0,16753212 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,13844353 0,16742219 ! female gamete generation GO:0007292 20 20 0,000 0,13844353 0,16731241 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,13844353 0,16720277 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,13844353 0,16709327 ! RNA modification GO:0009451 20 20 0,000 0,13844353 0,16698391 ! single fertilization GO:0007338 21 20 0,000 0,13844353 0,1668747 ! regulation of B cell activation GO:0050864 20 20 0,000 0,13844353 0,16676563 ! chemotaxis GO:0006935 90 89 1,000 0,14072006 0,16939718 GO:0042330|taxis, ! mRNA catabolic process GO:0006402 21 21 0,000 0,14484868 0,17425335 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,14484868 0,17413968 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,14484868 0,17402616 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,14484868 0,17391279 ! Notch signaling pathway GO:0007219 22 21 0,000 0,14484868 0,17379956 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,14484868 0,17368648 ! ear morphogenesis GO:0042471 21 21 0,000 0,14484868 0,17357355 ! cholesterol transport GO:0030301 21 21 0,000 0,14484868 0,17346077 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,14484868 0,17334813 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,14484868 0,17323564 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,14484868 0,1731233 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,14484868 0,1730111 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,14484868 0,17289905 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,14484868 0,17278714 ! regulation of proteolysis GO:0030162 21 21 0,000 0,14484868 0,17267537 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,14484868 0,17256375 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,14484868 0,17245228 ! fatty acid metabolic process GO:0006631 93 92 1,000 0,14838722 0,1765511 ! RNA export from nucleus GO:0006405 22 22 0,000 0,15120715 0,17979018 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,15120715 0,17967426 ! regulation of ion transport GO:0043269 22 22 0,000 0,15120715 0,17955849 ! cell junction organization GO:0034330 23 22 0,000 0,15120715 0,17944287 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,15120715 0,1793274 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,15120715 0,17921208 ! ovulation cycle process GO:0022602 22 22 0,000 0,15120715 0,1790969 ! spindle organization GO:0007051 22 22 0,000 0,15120715 0,17898187 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,15120715 0,178867 ! cell chemotaxis GO:0060326 23 22 0,000 0,15120715 0,17875226 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,15120715 0,17863768 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,15120715 0,17852324 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,15120715 0,17840895 ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,15120715 0,1782948 ! detection of external stimulus GO:0009581 23 22 0,000 0,15120715 0,1781808 ! neuron migration GO:0001764 22 22 0,000 0,15120715 0,17806695 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,15120715 0,17795324 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,15120715 0,17783968 ! aerobic respiration GO:0009060 22 22 0,000 0,15120715 0,17772626 ! cytokine production GO:0001816 22 22 0,000 0,15120715 0,17761299 ! cytokinesis GO:0000910 23 22 0,000 0,15120715 0,17749986 ! cofactor metabolic process GO:0051186 95 94 1,000 0,15354648 0,18013123 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,15751926 0,1846743 ! viral infectious cycle GO:0019058 23 23 0,000 0,15751926 0,18455689 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,15751926 0,18443964 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,15751926 0,18432254 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,15751926 0,18420558 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,15751926 0,18408877 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,15751926 0,18397211 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,15751926 0,1838556 ! endocrine system development GO:0035270 23 23 0,000 0,15751926 0,18373924 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,15751926 0,18362302 ! female gonad development GO:0008585 23 23 0,000 0,15751926 0,18350695 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,15751926 0,18339103 ! lipid homeostasis GO:0055088 23 23 0,000 0,15751926 0,18327525 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,15751926 0,18315962 ! mitochondrial transport GO:0006839 24 24 0,000 0,16378534 0,19032559 ! regulation of action potential GO:0001508 24 24 0,000 0,16378534 0,19020566 ! gliogenesis GO:0042063 24 24 0,000 0,16378534 0,19008588 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,16378534 0,18996626 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,16378534 0,18984678 ! ovulation cycle GO:0042698 24 24 0,000 0,16378534 0,18972746 ! fertilization GO:0009566 25 24 0,000 0,16378534 0,18960828 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,16378534 0,18948925 ! glucan metabolic process GO:0044042 25 24 0,000 0,16378534 0,18937038 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! blood circulation GO:0008015 99 98 1,000 0,16397 0,18946502 GO:0003013|circulatory system process, ! muscle organ development GO:0007517 102 100 1,000 0,16923008 0,19542045 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,16923008 0,19529808 ! response to other organism GO:0051707 101 100 1,000 0,16923008 0,19517587 ! hemopoiesis GO:0030097 104 100 1,000 0,16923008 0,19505381 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,17000572 0,19582534 ! negative regulation of secretion GO:0051048 26 25 0,000 0,17000572 0,19570303 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,17000572 0,19558087 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,17000572 0,19545886 ! cellular component disassembly GO:0022411 26 25 0,000 0,17000572 0,195337 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,17000572 0,19521529 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,17000572 0,19509374 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,17000572 0,19497234 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,17000572 0,19485109 ! excretion GO:0007588 25 25 0,000 0,17000572 0,19472999 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,17000572 0,19460904 ! gastrulation GO:0007369 25 25 0,000 0,17000572 0,19448824 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,17000572 0,19436759 ! regulation of endocytosis GO:0030100 25 25 0,000 0,17000572 0,19424708 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,17000572 0,19412673 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,17000572 0,19400653 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,17000572 0,19388648 ! positive regulation of defense response GO:0031349 26 26 0,000 0,17618074 0,20080463 ! glycolysis GO:0006096 26 26 0,000 0,17618074 0,20068053 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,17618074 0,20055657 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,17618074 0,20043277 ! cellular defense response GO:0006968 26 26 0,000 0,17618074 0,20030913 ! double-strand break repair GO:0006302 27 26 0,000 0,17618074 0,20018563 ! regulation of protein secretion GO:0050708 26 26 0,000 0,17618074 0,20006229 ! germ cell development GO:0007281 27 26 0,000 0,17618074 0,1999391 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,17618074 0,19981606 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,17618074 0,19969317 ! chloride transport GO:0006821 27 27 0,000 0,1823107 0,20651421 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,1823107 0,20638736 ! learning or memory GO:0007611 28 27 0,000 0,1823107 0,20626066 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,1823107 0,20613412 ! peptide metabolic process GO:0006518 29 27 0,000 0,1823107 0,20600774 ! activation of caspase activity GO:0006919 27 27 0,000 0,1823107 0,20588151 ! mesenchymal cell development GO:0014031 29 27 0,000 0,1823107 0,20575543 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,1823107 0,20562951 ! defense response to bacterium GO:0042742 27 27 0,000 0,1823107 0,20550374 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,1823107 0,20537813 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,1823107 0,20525267 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,18839594 0,21197419 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! neuromuscular process GO:0050905 28 28 0,000 0,18839594 0,21184486 ! carbohydrate transport GO:0008643 28 28 0,000 0,18839594 0,21171568 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,18839594 0,21158667 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,18839594 0,21145781 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,18839594 0,2113291 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,18839594 0,21120056 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,18839594 0,21107217 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,19443678 0,21770776 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,19443678 0,21757558 ! leukocyte migration GO:0050900 30 29 0,000 0,19443678 0,21744356 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,19443678 0,21731169 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,19443678 0,21717999 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,19443678 0,21704844 ! tRNA processing GO:0008033 29 29 0,000 0,19443678 0,21691706 ! adult behavior GO:0030534 30 29 0,000 0,19443678 0,21678583 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,19443678 0,21665476 ! transition metal ion transport GO:0000041 31 30 0,000 0,20043353 0,22320181 ! RNA catabolic process GO:0006401 30 30 0,000 0,20043353 0,22306702 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,20043353 0,2229324 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,20043353 0,22279794 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,20043353 0,22266365 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,20043353 0,22252951 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,20043353 0,22239554 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,20043353 0,22226173 ! response to temperature stimulus GO:0009266 30 30 0,000 0,20043353 0,22212807 ! regulation of ossification GO:0030278 30 30 0,000 0,20043353 0,22199458 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,20043353 0,22186125 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,20043353 0,22172808 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,20043353 0,22159507 ! vesicle organization GO:0016050 30 30 0,000 0,20043353 0,22146222 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,20043353 0,22132953 ! establishment of organelle localization GO:0051656 31 30 0,000 0,20043353 0,221197 ! regulation of translational initiation GO:0006446 31 31 0,000 0,2063865 0,22763036 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,2063865 0,22749421 ! membrane fusion GO:0006944 31 31 0,000 0,2063865 0,22735823 ! B cell activation GO:0042113 31 31 0,000 0,2063865 0,22722242 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,2063865 0,22708676 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,2063865 0,22695127 ! ion transmembrane transport GO:0034220 31 31 0,000 0,2063865 0,22681594 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,2063865 0,22668076 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,2063865 0,22654576 ! digestion GO:0007586 31 31 0,000 0,2063865 0,22641091 ! regulation of heart contraction GO:0008016 31 31 0,000 0,2063865 0,22627622 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,2063865 0,22614169 ! extracellular matrix organization GO:0030198 31 31 0,000 0,2063865 0,22600732 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,2063865 0,22587311 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,2063865 0,22573906 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,2063865 0,22560517 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,21229602 0,23192742 ! cell redox homeostasis GO:0045454 32 32 0,000 0,21229602 0,23179003 ! muscle fiber development GO:0048747 32 32 0,000 0,21229602 0,23165279 ! glucose catabolic process GO:0006007 32 32 0,000 0,21229602 0,23151572 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,21229602 0,23137881 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,21229602 0,23124206 ! nuclear export GO:0051168 32 32 0,000 0,21229602 0,23110547 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,21229602 0,23096905 ! negative regulation of cell size GO:0045792 33 33 0,000 0,21816239 0,23721138 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,21816239 0,23707151 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,21816239 0,23693181 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,21816239 0,23679228 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,21816239 0,2366529 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,21816239 0,2365137 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,21816239 0,23637465 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,21816239 0,23623577 ! regulation of actin filament length GO:0030832 34 34 0,000 0,22398592 0,24239933 ! ear development GO:0043583 34 34 0,000 0,22398592 0,24225707 ! muscle cell differentiation GO:0042692 35 34 0,000 0,22398592 0,24211499 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,22398592 0,24197307 ! secondary metabolic process GO:0019748 34 34 0,000 0,22398592 0,24183131 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,22398592 0,24168973 ! detection of stimulus GO:0051606 36 34 0,000 0,22398592 0,2415483 ! acute inflammatory response GO:0002526 35 35 0,000 0,22976692 0,24763768 ! regulation of cellular component size GO:0032535 35 35 0,000 0,22976692 0,24749295 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,22976692 0,24734838 GO:0048609|reproductive process in a multicellular organism, ! inorganic anion transport GO:0015698 35 35 0,000 0,22976692 0,24720399 ! regulation of immune effector process GO:0002697 35 35 0,000 0,22976692 0,24705976 ! hydrogen transport GO:0006818 36 36 0,000 0,23550569 0,25308279 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,23550569 0,25293531 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,23550569 0,252788 ! female pregnancy GO:0007565 37 36 0,000 0,23550569 0,25264086 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,23550569 0,25249389 ! activation of immune response GO:0002253 36 36 0,000 0,23550569 0,25234709 ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,24120254 0,25830115 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,24120254 0,25815115 ! negative regulation of growth GO:0045926 37 37 0,000 0,24120254 0,25800132 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,24120254 0,25785167 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,24120254 0,25770219 ! positive regulation of secretion GO:0051047 39 38 0,000 0,24685776 0,26359145 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,24685776 0,26343882 ! exocytosis GO:0006887 40 38 0,000 0,24685776 0,26328637 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,24685776 0,26313409 ! hexose catabolic process GO:0019320 38 38 0,000 0,24685776 0,26298199 ! regulation of neurological system process GO:0031644 38 38 0,000 0,24685776 0,26283007 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,25247165 0,26865199 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,25247165 0,26849697 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,25247165 0,26834213 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,25247165 0,26818746 ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,25804451 0,27394933 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,25804451 0,27379161 ! organelle localization GO:0051640 41 40 0,000 0,25804451 0,27363408 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,26357664 0,2793397 ! regulation of caspase activity GO:0043281 41 41 0,000 0,26357664 0,27917916 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,26357664 0,2790188 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,26357664 0,27885863 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,26357664 0,27869865 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,26357664 0,27853884 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,26906831 0,28417931 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,26906831 0,28401655 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,26906831 0,28385398 ! alcohol catabolic process GO:0046164 43 43 0,000 0,27451984 0,28943939 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,27451984 0,28927391 ! humoral immune response GO:0006959 44 44 0,000 0,27993149 0,29480785 ! mRNA transport GO:0051028 44 44 0,000 0,27993149 0,29463949 ! vitamin metabolic process GO:0006766 44 44 0,000 0,27993149 0,29447131 ! amine biosynthetic process GO:0009309 46 45 0,000 0,28530357 0,29995121 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,28530357 0,2997802 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,28530357 0,29960939 ! Wnt receptor signaling pathway GO:0016055 46 45 0,000 0,28530357 0,29943877 ! protein processing GO:0016485 45 45 0,000 0,28530357 0,29926834 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,29063634 0,30468872 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,29063634 0,30451551 ! regulation of membrane potential GO:0042391 46 46 0,000 0,29063634 0,30434249 ! regulation of blood pressure GO:0008217 48 47 0,000 0,2959301 0,30970992 ! rhythmic process GO:0048511 47 47 0,000 0,2959301 0,30953415 ! calcium ion transport GO:0006816 48 48 0,000 0,30118512 0,31485206 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,30118512 0,31467357 ! divalent metal ion transport GO:0070838 49 49 0,000 0,30640168 0,31994238 ! response to nutrient GO:0007584 49 49 0,000 0,30640168 0,31976121 ! response to bacterium GO:0009617 50 49 0,000 0,30640168 0,31958025 ! regulation of defense response GO:0031347 50 50 0,000 0,31158006 0,32479755 ! chromatin assembly GO:0031497 50 50 0,000 0,31158006 0,32461394 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,31158006 0,32443054 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! regulation of neurogenesis GO:0050767 51 50 0,000 0,31158006 0,32424735 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,31672054 0,32941081 ! positive regulation of immune response GO:0050778 51 51 0,000 0,31672054 0,32922501 ! rRNA metabolic process GO:0016072 51 51 0,000 0,31672054 0,32903943 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,31672054 0,32885406 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,31672054 0,32866889 ! protein maturation GO:0051604 51 51 0,000 0,31672054 0,32848393 ! RNA localization GO:0006403 52 52 0,000 0,32182337 0,33358857 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,32182337 0,33340105 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,32182337 0,33321375 ! sodium ion transport GO:0006814 53 53 0,000 0,32688884 0,33826846 ! tRNA metabolic process GO:0006399 53 53 0,000 0,32688884 0,33807863 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,32688884 0,33788902 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,32688884 0,33769962 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,3319172 0,34270219 ! sulfur metabolic process GO:0006790 55 54 0,000 0,3319172 0,34251031 ! nucleosome organization GO:0034728 55 55 0,000 0,33690874 0,3474666 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,33690874 0,34727226 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,33690874 0,34707815 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,34186371 0,35198593 ! regulation of nervous system development GO:0051960 57 56 0,000 0,34186371 0,3517894 ! ATP metabolic process GO:0046034 57 57 0,000 0,34678237 0,35665173 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,34678237 0,35645282 ! innate immune response GO:0045087 58 58 0,000 0,35166499 0,36127011 ! dephosphorylation GO:0016311 60 59 0,000 0,35651182 0,36604528 ! regulation of cell development GO:0060284 60 59 0,000 0,35651182 0,36584147 ! sterol metabolic process GO:0016125 59 59 0,000 0,35651182 0,36563789 ! immune effector process GO:0002252 59 59 0,000 0,35651182 0,36543453 ! potassium ion transport GO:0006813 60 60 0,000 0,36132312 0,37016038 ! cellular respiration GO:0045333 62 61 0,000 0,36609915 0,37484485 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,36609915 0,37463672 ! lipid transport GO:0006869 62 62 0,000 0,37084016 0,3792777 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,37084016 0,37906734 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,37084016 0,37885722 ! regulation of secretion GO:0051046 65 63 0,000 0,3755464 0,38345264 ! glucose metabolic process GO:0006006 63 63 0,000 0,3755464 0,38324032 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,3755464 0,38302823 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,38021813 0,38757854 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,38021813 0,38736429 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,38945901 0,39655964 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,38945901 0,39634067 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,39402866 0,40076976 ! muscle contraction GO:0006936 67 67 0,000 0,39402866 0,40054871 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,39856477 0,40493653 ! sensory perception of sound GO:0007605 71 69 0,000 0,40306759 0,40928571 GO:0050954|sensory perception of mechanical stimulus, ! response to nutrient levels GO:0031667 69 69 0,000 0,40306759 0,40906033 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,40753735 0,41336892 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,41197429 0,41763951 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,41197429 0,41740991 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,41197429 0,41718056 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,41197429 0,41695147 ! secretion by cell GO:0032940 75 72 0,000 0,41637866 0,42117775 ! muscle system process GO:0003012 72 72 0,000 0,41637866 0,42094672 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,41637866 0,42071594 ! electron transport chain GO:0022900 75 74 0,000 0,42509058 0,42928325 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,43367496 0,43771246 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,4379199 0,441755 ! metal ion homeostasis GO:0055065 78 78 0,000 0,44213364 0,44576166 ! regulation of immune response GO:0050776 78 78 0,000 0,44213364 0,44551794 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,45046843 0,45366848 ! ncRNA processing GO:0034470 83 83 0,000 0,46274218 0,4657749 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,46677339 0,46957607 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,47474705 0,47733705 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,47474705 0,47707678 ! male gamete generation GO:0048232 90 88 0,000 0,48260378 0,48470778 GO:0007283|spermatogenesis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,48648883 0,48834363 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,49034526 0,49194683 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,4941733 0,49551763 ! visual perception GO:0007601 93 92 0,000 0,49797315 0,49905629 GO:0050953|sensory perception of light stimulus, ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,49797315 0,49878506 ! endocytosis GO:0006897 99 98 0,000 0,52019148 0,5207566 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,52019148 0,52047388 ! regulation of system process GO:0044057 98 98 0,000 0,52019148 0,52019148