pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6497-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 9,000 9,16E-13 2,204E-09 ! positive regulation of cell migration GO:0030335 126 57 5,000 8,76E-07 1,054E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 6,000 1,221E-06 9,793E-04 ! interphase GO:0051325 213 98 6,000 1,507E-06 9,065E-04 ! positive regulation of cell motion GO:0051272 146 64 5,000 1,751E-06 8,428E-04 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 2,000 1,784E-06 7,152E-04 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 3,000 2,254E-06 7,748E-04 ! lung development GO:0030324 144 67 5,000 2,299E-06 6,913E-04 ! respiratory tube development GO:0030323 150 70 5,000 2,978E-06 7,961E-04 ! respiratory system development GO:0060541 153 72 5,000 3,515E-06 8,458E-04 ! N-terminal protein amino acid acetylation GO:0006474 13 7 2,000 6,191E-06 1,354E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 4,000 6,318E-06 1,267E-03 ! glutamate signaling pathway GO:0007215 41 22 3,000 6,776E-06 1,254E-03 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 9,756E-06 1,677E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 9,863E-06 1,582E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 2,000 9,863E-06 1,483E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 3,000 1,156E-05 1,637E-03 ! synapse organization GO:0050808 85 52 4,000 1,165E-05 1,558E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 1,361E-05 1,723E-03 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of MAP kinase activity GO:0043406 160 93 5,000 1,554E-05 1,87E-03 ! synaptogenesis GO:0007416 42 28 3,000 1,847E-05 2,116E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 2,096E-05 2,292E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 2,000 2,096E-05 2,193E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 2,361E-05 2,367E-03 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 2,000 2,87E-05 2,762E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 2,000 2,87E-05 2,656E-03 ! embryonic gut development GO:0048566 15 11 2,000 2,87E-05 2,557E-03 ! regulation of B cell proliferation GO:0030888 20 12 2,000 3,811E-05 3,274E-03 ! histone acetylation GO:0016573 26 12 2,000 3,811E-05 3,161E-03 ! peptidyl-lysine modification GO:0018205 21 12 2,000 3,811E-05 3,056E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 2,000 3,811E-05 2,957E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 4,000 4,043E-05 3,04E-03 ! cell cycle checkpoint GO:0000075 137 69 4,000 4,662E-05 3,399E-03 ! regulation of protein stability GO:0031647 73 37 3,000 5,725E-05 4,051E-03 ! N-terminal protein amino acid modification GO:0031365 27 14 2,000 6,252E-05 4,298E-03 ! actin cytoskeleton reorganization GO:0031532 33 14 2,000 6,252E-05 4,179E-03 ! regulation of catabolic process GO:0009894 161 76 4,000 7,423E-05 4,827E-03 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 2,000 7,783E-05 4,928E-03 ! response to metal ion GO:0010038 140 80 4,000 9,484E-05 5,851E-03 ! regulation of intracellular protein transport GO:0033157 80 42 3,000 9,49E-05 5,708E-03 ! positive regulation of protein import into nucleus GO:0042307 30 16 2,000 9,539E-05 5,598E-03 ! response to hypoxia GO:0001666 171 81 4,000 1,006E-04 5,764E-03 ! response to oxygen levels GO:0070482 176 83 4,000 1,13E-04 6,322E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,153E-04 6,307E-03 ! negative regulation of protein catabolic process GO:0042177 40 17 2,000 1,153E-04 6,167E-03 ! response to inorganic substance GO:0010035 153 86 4,000 1,337E-04 6,992E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 1,359E-04 6,959E-03 ! response to calcium ion GO:0051592 81 47 3,000 1,479E-04 7,415E-03 ! positive regulation of cell cycle GO:0045787 89 48 3,000 1,607E-04 7,889E-03 ! regulation of postsynaptic membrane potential GO:0060078 32 19 2,000 1,63E-04 7,844E-03 ! cellular response to unfolded protein GO:0034620 33 19 2,000 1,63E-04 7,69E-03 GO:0030968|endoplasmic reticulum unfolded protein response, ! regulation of endothelial cell migration GO:0010594 44 19 2,000 1,63E-04 7,542E-03 ! visual learning GO:0008542 36 19 2,000 1,63E-04 7,4E-03 ! protein amino acid acetylation GO:0006473 39 20 2,000 1,91E-04 8,509E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 1,91E-04 8,354E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 1,91E-04 8,205E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 1,91E-04 8,061E-03 ! reciprocal meiotic recombination GO:0007131 39 21 2,000 2,219E-04 9,204E-03 ! positive regulation of locomotion GO:0040017 39 21 2,000 2,219E-04 9,048E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! gut development GO:0048565 39 21 2,000 2,219E-04 8,897E-03 ! response to UV GO:0009411 104 53 3,000 2,365E-04 9,328E-03 ! regulation of chemotaxis GO:0050920 40 22 2,000 2,558E-04 9,928E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 2,558E-04 9,77E-03 ! apoptotic nuclear changes GO:0030262 32 22 2,000 2,558E-04 9,617E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 2,558E-04 9,469E-03 ! protein stabilization GO:0050821 39 22 2,000 2,558E-04 9,326E-03 ! cell cycle arrest GO:0007050 213 100 4,000 2,711E-04 9,736E-03 ! regulation of protein catabolic process GO:0042176 116 55 3,000 2,73E-04 9,661E-03 ! negative regulation of cell motion GO:0051271 134 55 3,000 2,73E-04 9,521E-03 ! regulation of DNA replication GO:0006275 101 56 3,000 2,927E-04 0,01006202 ! positive regulation of DNA replication GO:0045740 43 23 2,000 2,93E-04 9,928E-03 ! visual behavior GO:0007632 42 23 2,000 2,93E-04 9,79E-03 ! response to ethanol GO:0045471 46 23 2,000 2,93E-04 9,656E-03 ! sex determination GO:0007530 47 23 2,000 2,93E-04 9,526E-03 ! negative regulation of catabolic process GO:0009895 50 23 2,000 2,93E-04 9,399E-03 ! regulation of intracellular transport GO:0032386 101 57 3,000 3,135E-04 9,923E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 3,169E-04 9,903E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 3,169E-04 9,776E-03 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 1,000 3,169E-04 9,652E-03 ! positive regulation of viral genome replication GO:0045070 9 5 1,000 3,169E-04 9,531E-03 ! regulation of retroviral genome replication GO:0045091 7 5 1,000 3,169E-04 9,414E-03 ! microvillus organization GO:0032528 7 5 1,000 3,169E-04 9,299E-03 GO:0030033|microvillus assembly, ! positive regulation of filopodium assembly GO:0051491 14 5 1,000 3,169E-04 9,187E-03 GO:0051489|regulation of filopodium assembly, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 3,169E-04 9,078E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 3,169E-04 8,971E-03 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 1,000 3,169E-04 8,866E-03 ! regulation of sensory perception GO:0051931 7 5 1,000 3,169E-04 8,765E-03 GO:0051930|regulation of sensory perception of pain, ! stem cell division GO:0017145 11 5 1,000 3,169E-04 8,665E-03 GO:0048103|somatic stem cell division, ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 3,334E-04 9,014E-03 ! regulation of behavior GO:0050795 43 24 2,000 3,334E-04 8,914E-03 ! membrane depolarization GO:0051899 39 24 2,000 3,334E-04 8,816E-03 ! skeletal system morphogenesis GO:0048705 105 59 3,000 3,58E-04 9,362E-03 ! chromosome condensation GO:0030261 45 25 2,000 3,773E-04 9,762E-03 ! response to endoplasmic reticulum stress GO:0034976 43 25 2,000 3,773E-04 9,658E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 4,248E-04 0,01075775 ! regulation of endothelial cell proliferation GO:0001936 57 26 2,000 4,248E-04 0,01064569 ! forebrain regionalization GO:0021871 8 6 1,000 4,736E-04 0,01174747 ! response to zinc ion GO:0010043 9 6 1,000 4,736E-04 0,01162759 ! regulation of respiratory gaseous exchange GO:0043576 8 6 1,000 4,736E-04 0,01151014 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 1,000 4,736E-04 0,01139504 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 1,000 4,736E-04 0,01128222 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 1,000 4,736E-04 0,01117161 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! hyperosmotic response GO:0006972 9 6 1,000 4,736E-04 0,01106315 ! negative regulation of platelet activation GO:0010544 9 6 1,000 4,736E-04 0,01095677 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 1,000 4,736E-04 0,01085242 ! deoxyribonucleoside metabolic process GO:0009120 8 6 1,000 4,736E-04 0,01075004 ! nucleoside catabolic process GO:0009164 7 6 1,000 4,736E-04 0,01064957 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 1,000 4,736E-04 0,01055096 ! ectodermal gut morphogenesis GO:0048567 12 6 1,000 4,736E-04 0,01045417 GO:0007439|ectodermal gut development, ! negative regulation of B cell activation GO:0050869 13 6 1,000 4,736E-04 0,01035913 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 4,759E-04 0,01031489 ! protein amino acid acylation GO:0043543 55 27 2,000 4,759E-04 0,01022279 ! ER-nuclear signaling pathway GO:0006984 48 28 2,000 5,308E-04 0,01130101 ! activation of MAPK activity GO:0000187 115 67 3,000 5,82E-04 0,01228363 ! urogenital system development GO:0001655 137 69 3,000 6,507E-04 0,01361372 ! regulation of B cell activation GO:0050864 50 30 2,000 6,523E-04 0,01353013 ! prostate gland development GO:0030850 13 7 1,000 6,606E-04 0,01358417 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 6,606E-04 0,01346905 ! neuron adhesion GO:0007158 12 7 1,000 6,606E-04 0,01335587 ! mRNA stabilization GO:0048255 18 7 1,000 6,606E-04 0,01324457 GO:0043489|RNA stabilization, ! spinal cord patterning GO:0021511 13 7 1,000 6,606E-04 0,01313511 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 1,000 6,606E-04 0,01302744 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! purine salvage GO:0043101 10 7 1,000 6,606E-04 0,01292153 ! spindle checkpoint GO:0031577 15 7 1,000 6,606E-04 0,01281732 ! cranial nerve morphogenesis GO:0021602 11 7 1,000 6,606E-04 0,01271478 ! regulation of respiratory burst GO:0060263 11 7 1,000 6,606E-04 0,01261387 ! axonal fasciculation GO:0007413 18 7 1,000 6,606E-04 0,01251455 ! negative regulation of nuclear division GO:0051784 14 7 1,000 6,606E-04 0,01241678 GO:0045839|negative regulation of mitosis, ! negative regulation of transcription regulator activity GO:0090048 58 31 2,000 7,192E-04 0,01341423 GO:0043433|negative regulation of transcription factor activity, ! regulation of protein import into nucleus GO:0042306 63 32 2,000 7,903E-04 0,01462703 ! positive regulation of catabolic process GO:0009896 64 32 2,000 7,903E-04 0,01451538 ! axon guidance GO:0007411 139 73 3,000 8,05E-04 0,01467223 ! regulation of transcription factor activity GO:0051090 126 74 3,000 8,472E-04 0,0153265 GO:0090046|regulation of transcription regulator activity, ! DNA damage checkpoint GO:0000077 71 33 2,000 8,657E-04 0,01554462 ! negative regulation of protein transport GO:0051224 69 33 2,000 8,657E-04 0,01542948 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 1,000 8,775E-04 0,01552368 ! neurotransmitter uptake GO:0001504 14 8 1,000 8,775E-04 0,01541037 ! glycine catabolic process GO:0006546 13 8 1,000 8,775E-04 0,0152987 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 1,000 8,775E-04 0,01518864 ! L-phenylalanine metabolic process GO:0006558 11 8 1,000 8,775E-04 0,01508015 GO:0006559|L-phenylalanine catabolic process, ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 8,775E-04 0,01497319 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 8,775E-04 0,01486775 ! T-helper 1 type immune response GO:0042088 12 8 1,000 8,775E-04 0,01476378 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 8,775E-04 0,01466125 ! regulation of vascular permeability GO:0043114 12 8 1,000 8,775E-04 0,01456014 ! DNA topological change GO:0006265 12 8 1,000 8,775E-04 0,01446041 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 8,775E-04 0,01436204 ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 1,000 8,775E-04 0,014265 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! trophectodermal cell differentiation GO:0001829 13 8 1,000 8,775E-04 0,01416926 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 8,775E-04 0,0140748 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 2,000 1,03E-03 0,01641082 ! embryonic skeletal system morphogenesis GO:0048704 59 35 2,000 1,03E-03 0,01630285 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 3,000 1,082E-03 0,01701938 ! cell junction organization GO:0034330 86 36 2,000 1,119E-03 0,01748111 ! maintenance of protein location in cell GO:0032507 86 36 2,000 1,119E-03 0,01736833 ! DNA integrity checkpoint GO:0031570 75 36 2,000 1,119E-03 0,017257 ! embryonic organ development GO:0048568 57 36 2,000 1,119E-03 0,01714708 ! negative regulation of cell activation GO:0050866 65 36 2,000 1,119E-03 0,01703855 ! regulation of developmental growth GO:0048638 15 9 1,000 1,124E-03 0,01700816 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,124E-03 0,01690186 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 1,124E-03 0,01679688 GO:0010469|regulation of receptor activity, ! induction of positive chemotaxis GO:0050930 15 9 1,000 1,124E-03 0,0166932 ! regulation of glycolysis GO:0006110 21 9 1,000 1,124E-03 0,01659079 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,124E-03 0,01648962 ! receptor clustering GO:0043113 18 9 1,000 1,124E-03 0,01638969 ! protein heterooligomerization GO:0051291 16 9 1,000 1,124E-03 0,01629095 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 1,124E-03 0,0161934 ! spinal cord motor neuron differentiation GO:0021522 15 9 1,000 1,124E-03 0,01609701 ! serine family amino acid catabolic process GO:0009071 16 9 1,000 1,124E-03 0,01600176 ! meiosis I GO:0007127 65 37 2,000 1,213E-03 0,01716162 ! negative regulation of DNA binding GO:0043392 68 37 2,000 1,213E-03 0,01706126 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 1,213E-03 0,01696207 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 1,311E-03 0,01823357 ! carbohydrate homeostasis GO:0033500 53 38 2,000 1,311E-03 0,01812878 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 67 38 2,000 1,311E-03 0,01802519 ! regulation of ligase activity GO:0051340 142 84 3,000 1,36E-03 0,01858749 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 1,4E-03 0,01902692 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 1,000 1,4E-03 0,01892003 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,4E-03 0,01881433 ! smoothened signaling pathway GO:0007224 16 10 1,000 1,4E-03 0,01870981 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 1,000 1,4E-03 0,01860644 ! lung alveolus development GO:0048286 26 10 1,000 1,4E-03 0,01850421 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 1,4E-03 0,01840309 ! epithelial cell development GO:0002064 20 10 1,000 1,4E-03 0,01830307 ! regulation of bone resorption GO:0045124 25 10 1,000 1,4E-03 0,01820414 ! alpha-beta T cell activation GO:0046631 23 10 1,000 1,4E-03 0,01810627 ! DNA ligation GO:0006266 19 10 1,000 1,4E-03 0,01800944 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 1,000 1,4E-03 0,01791365 ! cellular metabolic compound salvage GO:0043094 14 10 1,000 1,4E-03 0,01781886 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,4E-03 0,01772508 ! positive regulation of viral reproduction GO:0048524 18 10 1,000 1,4E-03 0,01763228 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,4E-03 0,01754044 GO:0043470|regulation of carbohydrate catabolic process, ! blastocyst formation GO:0001825 17 10 1,000 1,4E-03 0,01744956 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,4E-03 0,01735962 ! localization within membrane GO:0051668 20 10 1,000 1,4E-03 0,01727059 ! learning GO:0007612 77 39 2,000 1,414E-03 0,01736279 ! tube morphogenesis GO:0035239 176 86 3,000 1,483E-03 0,01811654 ! mitochondrion organization GO:0007005 148 86 3,000 1,483E-03 0,01802505 ! negative regulation of binding GO:0051100 72 40 2,000 1,523E-03 0,01841098 ! maintenance of protein location GO:0045185 91 40 2,000 1,523E-03 0,01831892 ! nitrogen compound catabolic process GO:0044270 143 87 3,000 1,548E-03 0,01853028 ! regulation of protein transport GO:0051223 154 87 3,000 1,548E-03 0,01843855 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 3,000 1,615E-03 0,01913732 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 2,000 1,636E-03 0,0192973 ! regulation of T cell differentiation GO:0045580 70 41 2,000 1,636E-03 0,01920317 ! negative regulation of muscle development GO:0048635 20 11 1,000 1,704E-03 0,01990686 ! neuron fate specification GO:0048665 17 11 1,000 1,704E-03 0,01981069 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,704E-03 0,01971545 ! blood vessel remodeling GO:0001974 29 11 1,000 1,704E-03 0,01962112 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,704E-03 0,01952768 GO:0010812|negative regulation of cell-substrate adhesion, ! ventral spinal cord development GO:0021517 21 11 1,000 1,704E-03 0,01943513 ! substrate-bound cell migration GO:0006929 13 11 1,000 1,704E-03 0,01934346 ! adult heart development GO:0007512 14 11 1,000 1,704E-03 0,01925264 ! DNA methylation GO:0006306 19 11 1,000 1,704E-03 0,01916268 GO:0006305|DNA alkylation, ! regulation of leukocyte migration GO:0002685 26 11 1,000 1,704E-03 0,01907355 ! regulation of embryonic development GO:0045995 27 11 1,000 1,704E-03 0,01898525 ! regulation of cell cycle process GO:0010564 149 90 3,000 1,754E-03 0,01944575 ! neuron migration GO:0001764 79 42 2,000 1,755E-03 0,01936653 ! epithelial cell differentiation GO:0030855 79 43 2,000 1,879E-03 0,02063813 ! positive regulation of response to external stimulus GO:0032103 77 43 2,000 1,879E-03 0,02054432 ! neural tube development GO:0021915 77 43 2,000 1,879E-03 0,02045136 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 1,879E-03 0,02035923 ! maintenance of location in cell GO:0051651 97 44 2,000 2,008E-03 0,02166089 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 2,038E-03 0,02188678 ! virus-host interaction GO:0019048 29 12 1,000 2,038E-03 0,02178951 ! cartilage condensation GO:0001502 20 12 1,000 2,038E-03 0,02169309 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 2,038E-03 0,02159753 GO:0050927|positive regulation of positive chemotaxis, ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,038E-03 0,0215028 ! regulation of cell projection assembly GO:0060491 30 12 1,000 2,038E-03 0,02140891 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,038E-03 0,02131582 ! tyrosine metabolic process GO:0006570 16 12 1,000 2,038E-03 0,02122355 ! focal adhesion formation GO:0048041 35 12 1,000 2,038E-03 0,02113207 ! L-glutamate transport GO:0015813 22 12 1,000 2,038E-03 0,02104137 GO:0015800|acidic amino acid transport, ! synaptic vesicle exocytosis GO:0016079 19 12 1,000 2,038E-03 0,02095145 ! regulation of interleukin-12 production GO:0032655 19 12 1,000 2,038E-03 0,02086229 ! cranial nerve development GO:0021545 20 12 1,000 2,038E-03 0,0207739 ! aromatic amino acid family catabolic process GO:0009074 18 12 1,000 2,038E-03 0,02068624 ! digestive tract morphogenesis GO:0048546 26 12 1,000 2,038E-03 0,02059932 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 2,038E-03 0,02051314 GO:0042130|negative regulation of T cell proliferation, ! branching morphogenesis of a tube GO:0048754 97 45 2,000 2,142E-03 0,02147492 ! negative regulation of cell migration GO:0030336 115 46 2,000 2,282E-03 0,02278317 ! response to insulin stimulus GO:0032868 95 46 2,000 2,282E-03 0,02268903 ! positive regulation of protein transport GO:0051222 72 46 2,000 2,282E-03 0,02259566 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 2,306E-03 0,02274252 ! regulation of protein localization GO:0032880 176 97 3,000 2,306E-03 0,02264969 ! carboxylic acid catabolic process GO:0046395 156 98 3,000 2,394E-03 0,02341481 GO:0016054|organic acid catabolic process, ! regulation of cell-cell adhesion GO:0022407 33 13 1,000 2,399E-03 0,02337024 ! negative regulation of lipid metabolic process GO:0045833 19 13 1,000 2,399E-03 0,023276 ! deoxyribonucleotide catabolic process GO:0009264 19 13 1,000 2,399E-03 0,02318252 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 1,000 2,399E-03 0,02308979 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,399E-03 0,0229978 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! nucleoside triphosphate catabolic process GO:0009143 21 13 1,000 2,399E-03 0,02290654 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 2,399E-03 0,022816 ! regulation of mRNA stability GO:0043488 31 13 1,000 2,399E-03 0,02272617 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 2,399E-03 0,02263705 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 2,579E-03 0,0242362 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 2,579E-03 0,0241419 ! pteridine and derivative biosynthetic process GO:0042559 19 14 1,000 2,789E-03 0,02600563 ! hair follicle morphogenesis GO:0031069 26 14 1,000 2,789E-03 0,02590522 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 1,000 2,789E-03 0,02580558 ! regulation of mRNA processing GO:0050684 24 14 1,000 2,789E-03 0,02570671 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 2,789E-03 0,02560859 GO:0060675|ureteric bud morphogenesis, ! L-amino acid transport GO:0015807 30 14 1,000 2,789E-03 0,02551122 ! regulation of RNA stability GO:0043487 32 14 1,000 2,789E-03 0,02541459 ! histone modification GO:0016570 91 50 2,000 2,898E-03 0,026313 ! embryonic skeletal system development GO:0048706 85 51 2,000 3,067E-03 0,02773735 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 2,000 3,067E-03 0,02763346 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 3,067E-03 0,02753035 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 2,000 3,067E-03 0,02742801 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 3,206E-03 0,02856617 ! heterophilic cell adhesion GO:0007157 39 15 1,000 3,206E-03 0,02846076 ! covalent chromatin modification GO:0016569 101 52 2,000 3,241E-03 0,0286673 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 3,241E-03 0,02856229 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,65E-03 0,0320508 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 3,65E-03 0,03193425 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 3,65E-03 0,03181855 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 3,65E-03 0,03170368 ! startle response GO:0001964 28 16 1,000 3,65E-03 0,03158964 ! response to osmotic stress GO:0006970 25 16 1,000 3,65E-03 0,03147641 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 1,000 3,65E-03 0,031364 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 1,000 3,65E-03 0,03125238 ! neuron recognition GO:0008038 35 16 1,000 3,65E-03 0,03114156 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 3,65E-03 0,03103152 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 3,65E-03 0,03092225 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 3,65E-03 0,03081375 ! RNA elongation GO:0006354 79 55 2,000 3,8E-03 0,03196591 ! nucleotide-excision repair GO:0006289 83 56 2,000 3,998E-03 0,0335187 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 4,121E-03 0,03443 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 1,000 4,121E-03 0,03431086 GO:0019692|deoxyribose phosphate metabolic process, ! signal complex assembly GO:0007172 41 17 1,000 4,121E-03 0,03419255 ! regulation of viral genome replication GO:0045069 28 17 1,000 4,121E-03 0,03407505 ! cell differentiation in spinal cord GO:0021515 30 17 1,000 4,121E-03 0,03395835 ! glycine metabolic process GO:0006544 28 17 1,000 4,121E-03 0,03384245 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 4,121E-03 0,03372734 ! negative regulation of blood coagulation GO:0030195 24 17 1,000 4,121E-03 0,03361301 ! aromatic compound biosynthetic process GO:0019438 24 17 1,000 4,121E-03 0,03349946 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 4,121E-03 0,03338666 ! lipid modification GO:0030258 97 57 2,000 4,203E-03 0,03393425 ! maintenance of location GO:0051235 118 57 2,000 4,203E-03 0,03382075 ! regulation of lipid biosynthetic process GO:0046890 25 18 1,000 4,619E-03 0,03704621 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 4,619E-03 0,03692314 ! epidermis morphogenesis GO:0048730 40 18 1,000 4,619E-03 0,03680087 ! cell-substrate junction assembly GO:0007044 54 18 1,000 4,619E-03 0,03667942 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 4,619E-03 0,03655876 ! aromatic compound catabolic process GO:0019439 27 18 1,000 4,619E-03 0,0364389 ! nerve development GO:0021675 28 18 1,000 4,619E-03 0,03631982 ! DNA catabolic process GO:0006308 86 59 2,000 4,631E-03 0,03629573 ! regulation of neurotransmitter levels GO:0001505 97 60 2,000 4,855E-03 0,03792498 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 4,855E-03 0,03780225 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 5,085E-03 0,03946595 ! lipid phosphorylation GO:0046834 35 19 1,000 5,143E-03 0,03979177 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 5,143E-03 0,03966423 ! forelimb morphogenesis GO:0035136 32 19 1,000 5,143E-03 0,03953751 ! bile acid metabolic process GO:0008206 29 19 1,000 5,143E-03 0,03941159 ! actin filament bundle formation GO:0051017 42 19 1,000 5,143E-03 0,03928647 ! cell-cell junction organization GO:0045216 35 19 1,000 5,143E-03 0,03916215 ! purine nucleotide catabolic process GO:0006195 29 19 1,000 5,143E-03 0,03903861 ! proximal/distal pattern formation GO:0009954 32 19 1,000 5,143E-03 0,03891585 ! embryonic organ morphogenesis GO:0048562 26 19 1,000 5,143E-03 0,03879385 ! regulation of mitosis GO:0007088 105 63 2,000 5,565E-03 0,04183862 GO:0051783|regulation of nuclear division, ! cellular amino acid catabolic process GO:0009063 101 63 2,000 5,565E-03 0,04170828 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 5,694E-03 0,04254415 ! pteridine and derivative metabolic process GO:0042558 29 20 1,000 5,694E-03 0,04241243 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 5,694E-03 0,04228153 GO:0010675|regulation of cellular carbohydrate metabolic process, ! D-ribose metabolic process GO:0006014 29 20 1,000 5,694E-03 0,04215143 ! fatty acid beta-oxidation GO:0006635 34 20 1,000 5,694E-03 0,04202213 ! camera-type eye morphogenesis GO:0048593 42 20 1,000 5,694E-03 0,04189362 ! negative regulation of T cell activation GO:0050868 40 20 1,000 5,694E-03 0,0417659 ! negative regulation of translation GO:0017148 29 20 1,000 5,694E-03 0,04163895 ! negative regulation of coagulation GO:0050819 29 20 1,000 5,694E-03 0,04151277 ! embryonic limb morphogenesis GO:0030326 125 65 2,000 6,07E-03 0,04412525 GO:0035113|embryonic appendage morphogenesis, ! hindlimb morphogenesis GO:0035137 43 21 1,000 6,27E-03 0,04543689 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 6,27E-03 0,04530044 ! DNA modification GO:0006304 34 21 1,000 6,27E-03 0,04516481 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 6,27E-03 0,04502999 ! actin filament organization GO:0007015 148 66 2,000 6,333E-03 0,04535112 ! cell projection assembly GO:0030031 120 66 2,000 6,333E-03 0,04521655 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 6,603E-03 0,04700182 ! negative regulation of cell growth GO:0030308 132 67 2,000 6,603E-03 0,04686318 ! chromosome segregation GO:0007059 113 67 2,000 6,603E-03 0,04672534 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 6,871E-03 0,04848094 ! deoxyribonucleotide metabolic process GO:0009262 32 22 1,000 6,871E-03 0,04833918 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 6,871E-03 0,04819825 ! ureteric bud development GO:0001657 43 22 1,000 6,871E-03 0,04805814 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 6,871E-03 0,04791884 ! positive regulation of B cell activation GO:0050871 38 22 1,000 6,871E-03 0,04778035 ! activation of JUN kinase activity GO:0007257 42 22 1,000 6,871E-03 0,04764265 ! aromatic amino acid family metabolic process GO:0009072 32 22 1,000 6,871E-03 0,04750575 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 6,871E-03 0,04736963 ! negative regulation of kinase activity GO:0033673 131 68 2,000 6,879E-03 0,04728993 ! negative regulation of ligase activity GO:0051352 112 68 2,000 6,879E-03 0,0471552 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 2,000 6,879E-03 0,04702124 ! negative regulation of cell size GO:0045792 134 69 2,000 7,162E-03 0,04881772 ! appendage morphogenesis GO:0035107 135 70 2,000 7,452E-03 0,0506504 GO:0035108|limb morphogenesis, ! gluconeogenesis GO:0006094 33 23 1,000 7,498E-03 0,05081506 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 1,000 7,498E-03 0,05067232 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 7,498E-03 0,05053038 GO:0010810|regulation of cell-substrate adhesion, ! purine ribonucleoside metabolic process GO:0046128 34 23 1,000 7,498E-03 0,05038923 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 1,000 7,498E-03 0,05024887 ! regulation of viral reproduction GO:0050792 38 23 1,000 7,498E-03 0,05010929 ! synaptic vesicle transport GO:0048489 46 23 1,000 7,498E-03 0,04997048 ! amine catabolic process GO:0009310 117 71 2,000 7,749E-03 0,05150368 ! reproductive structure development GO:0048608 113 71 2,000 7,749E-03 0,0513618 ! appendage development GO:0048736 136 71 2,000 7,749E-03 0,0512207 GO:0060173|limb development, ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 2,000 8,053E-03 0,05308223 ! negative regulation of transferase activity GO:0051348 140 72 2,000 8,053E-03 0,0529372 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 8,149E-03 0,05342331 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 8,149E-03 0,05327814 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 8,149E-03 0,05313375 ! spinal cord development GO:0021510 47 24 1,000 8,149E-03 0,05299015 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 8,149E-03 0,05284732 ! pentose metabolic process GO:0019321 35 24 1,000 8,149E-03 0,05270525 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 8,149E-03 0,05256395 ! protein tetramerization GO:0051262 52 24 1,000 8,149E-03 0,05242341 ! learning or memory GO:0007611 147 73 2,000 8,363E-03 0,05365965 ! neurotransmitter transport GO:0006836 123 74 2,000 8,681E-03 0,05554915 ! meiosis GO:0007126 121 74 2,000 8,681E-03 0,0554018 GO:0051327|M phase of meiotic cell cycle, ! vasculogenesis GO:0001570 46 25 1,000 8,825E-03 0,05617014 ! receptor metabolic process GO:0043112 46 25 1,000 8,825E-03 0,05602193 ! interaction with host GO:0051701 62 25 1,000 8,825E-03 0,0558745 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 8,825E-03 0,05572785 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 1,000 8,825E-03 0,05558197 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 1,000 8,825E-03 0,05543685 ! regulation of blood coagulation GO:0030193 40 25 1,000 8,825E-03 0,05529248 ! neural tube closure GO:0001843 49 25 1,000 8,825E-03 0,05514886 GO:0060606|tube closure, ! liver development GO:0001889 53 25 1,000 8,825E-03 0,05500599 ! cell-matrix adhesion GO:0007160 163 75 2,000 9,006E-03 0,05598817 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 9,006E-03 0,05584387 ! meiotic cell cycle GO:0051321 122 75 2,000 9,006E-03 0,05570032 ! pyruvate metabolic process GO:0006090 38 26 1,000 9,525E-03 0,05876027 ! molting cycle process GO:0022404 50 26 1,000 9,525E-03 0,05860999 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 1,000 9,525E-03 0,05846047 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 9,525E-03 0,05831172 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 9,525E-03 0,05816372 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 9,525E-03 0,05801647 ! cellular response to oxidative stress GO:0034599 39 26 1,000 9,525E-03 0,05786996 ! positive regulation of nuclear division GO:0051785 40 26 1,000 9,525E-03 0,0577242 GO:0045840|positive regulation of mitosis, ! blastocyst development GO:0001824 49 26 1,000 9,525E-03 0,05757916 ! positive regulation of JUN kinase activity GO:0043507 51 26 1,000 9,525E-03 0,05743485 ! positive regulation of lymphocyte activation GO:0051251 127 77 2,000 9,676E-03 0,05820027 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 2,000 0,01002161 0,06012966 ! neuron fate commitment GO:0048663 48 27 1,000 0,01024864 0,06133888 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 0,01024864 0,06118667 ! positive regulation of cell projection organization GO:0031346 58 27 1,000 0,01024864 0,06103522 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 0,01024864 0,06088452 ! fat cell differentiation GO:0045444 50 27 1,000 0,01024864 0,06073456 ! primary neural tube formation GO:0014020 51 27 1,000 0,01024864 0,06058533 ! base-excision repair GO:0006284 41 27 1,000 0,01024864 0,06043684 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 0,01024864 0,06028907 ! positive regulation of phosphorylation GO:0042327 129 79 2,000 0,01037448 0,06088048 ! negative regulation of protein modification process GO:0031400 60 28 1,000 0,01099617 0,06437174 ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 0,01099617 0,0642155 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,01099617 0,06406001 ! lipid oxidation GO:0034440 43 28 1,000 0,01099617 0,06390528 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 58 28 1,000 0,01099617 0,06375129 ! T cell activation GO:0042110 168 81 2,000 0,01110166 0,06420817 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 0,01110166 0,06405419 GO:0045937|positive regulation of phosphate metabolic process, ! cell-substrate adhesion GO:0031589 171 81 2,000 0,01110166 0,06390096 ! regulation of neuron differentiation GO:0045664 167 81 2,000 0,01110166 0,06374845 ! response to drug GO:0042493 143 82 2,000 0,01147603 0,06574124 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 0,01147603 0,06558508 ! response to organic cyclic substance GO:0014070 55 29 1,000 0,01176703 0,06708881 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 0,01176703 0,06693021 ! tissue homeostasis GO:0001894 48 29 1,000 0,01176703 0,06677235 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 1,000 0,01176703 0,06661524 ! negative regulation of transport GO:0051051 153 84 2,000 0,01224642 0,06916638 ! negative regulation of growth GO:0045926 155 84 2,000 0,01224642 0,0690044 ! cell junction assembly GO:0034329 78 30 1,000 0,01256094 0,07061126 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 0,01256094 0,07044666 ! neurotransmitter secretion GO:0007269 48 30 1,000 0,01256094 0,07028283 ! eye morphogenesis GO:0048592 60 30 1,000 0,01256094 0,07011976 ! response to unfolded protein GO:0006986 131 85 2,000 0,01264248 0,07041161 ! positive regulation of cell activation GO:0050867 145 85 2,000 0,01264248 0,07024899 GO:0002696|positive regulation of leukocyte activation, ! serine family amino acid metabolic process GO:0009069 49 31 1,000 0,01337761 0,07416251 ! fatty acid catabolic process GO:0009062 48 31 1,000 0,01337761 0,07399202 ! gland development GO:0048732 206 88 2,000 0,01387441 0,07656381 ! regulation of neurological system process GO:0031644 148 88 2,000 0,01387441 0,07638861 ! metanephros development GO:0001656 74 32 1,000 0,01421676 0,07809481 ! hexose biosynthetic process GO:0019319 48 32 1,000 0,01421676 0,07791692 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 0,01421676 0,07773984 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,01429968 0,07801593 ! ossification GO:0001503 188 90 2,000 0,01473229 0,08019434 ! cell fate specification GO:0001708 52 33 1,000 0,01507812 0,08189154 ! adult locomotory behavior GO:0008344 59 33 1,000 0,01507812 0,0817071 ! establishment of vesicle localization GO:0051650 61 33 1,000 0,01507812 0,08152349 ! bone development GO:0060348 189 91 2,000 0,01517227 0,08184859 ! response to protein stimulus GO:0051789 149 91 2,000 0,01517227 0,08166549 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,0159614 0,08572127 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 1,000 0,0159614 0,08553036 ! placenta development GO:0001890 53 34 1,000 0,0159614 0,08534029 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,0159614 0,08515107 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 2,000 0,01607433 0,08556381 GO:0010498|proteasomal protein catabolic process, ! regulation of membrane potential GO:0042391 164 93 2,000 0,01607433 0,08537493 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 0,01607433 0,08518688 ! transcription initiation GO:0006352 153 94 2,000 0,01653645 0,08744329 ! regulation of T cell activation GO:0050863 158 94 2,000 0,01653645 0,08725153 ! regulation of muscle development GO:0048634 70 35 1,000 0,01686634 0,0887974 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01686634 0,08860351 ! odontogenesis GO:0042476 66 35 1,000 0,01686634 0,08841048 ! telencephalon development GO:0021537 68 35 1,000 0,01686634 0,08821828 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01686634 0,08802692 ! neural tube formation GO:0001841 67 35 1,000 0,01686634 0,08783638 ! vesicle localization GO:0051648 64 35 1,000 0,01686634 0,08764667 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,01779266 0,09226106 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,01779266 0,09206265 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,01779266 0,09186509 ! monosaccharide biosynthetic process GO:0046364 52 36 1,000 0,01779266 0,09166838 ! sister chromatid segregation GO:0000819 58 37 1,000 0,01874009 0,09634329 ! organic anion transport GO:0015711 68 37 1,000 0,01874009 0,09613786 ! tissue remodeling GO:0048771 76 37 1,000 0,01874009 0,09593331 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,01970837 0,10067588 ! nucleotide catabolic process GO:0009166 61 38 1,000 0,01970837 0,10046258 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,01970837 0,10025019 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,01970837 0,10003869 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 1,000 0,02069723 0,10483693 ! segmentation GO:0035282 67 39 1,000 0,02069723 0,10461668 ! multicellular organismal metabolic process GO:0044236 57 40 1,000 0,02170641 0,1094877 ! ribonucleoside metabolic process GO:0009119 55 40 1,000 0,02170641 0,10925864 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,02273566 0,1142004 ! T cell differentiation GO:0030217 81 41 1,000 0,02273566 0,11396248 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,02273566 0,11372555 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,0237847 0,11872613 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 0,0237847 0,11848032 ! alcohol biosynthetic process GO:0046165 59 42 1,000 0,0237847 0,11823553 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 0,0248533 0,12329285 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 1,000 0,0248533 0,12303916 ! heterocycle biosynthetic process GO:0018130 69 43 1,000 0,0248533 0,12278651 ! male sex differentiation GO:0046661 76 44 1,000 0,02594118 0,12789855 ! biopolymer methylation GO:0043414 84 44 1,000 0,02594118 0,12763699 ! developmental growth GO:0048589 82 44 1,000 0,02594118 0,12737651 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 0,02704812 0,13254128 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 1,000 0,02704812 0,13227189 ! cell growth GO:0016049 84 45 1,000 0,02704812 0,13200359 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02807057 0,13671617 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02807057 0,13643998 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02807057 0,1361649 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02807057 0,13589093 ! neuron fate determination GO:0048664 7 5 0,000 0,02807057 0,13561805 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02807057 0,13534627 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02807057 0,13507558 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02807057 0,13480597 ! polyol transport GO:0015791 12 5 0,000 0,02807057 0,13453743 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02807057 0,13426996 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02807057 0,13400355 ! response to superoxide GO:0000303 10 5 0,000 0,02807057 0,1337382 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02807057 0,13347389 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02807057 0,13321063 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02807057 0,13294841 ! female meiosis GO:0007143 7 5 0,000 0,02807057 0,13268721 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02807057 0,13242704 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02807057 0,13216789 ! cobalt ion transport GO:0006824 11 5 0,000 0,02807057 0,13190975 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02807057 0,13165261 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02807057 0,13139648 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02807057 0,13114134 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02807057 0,13088719 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02807057 0,13063402 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02807057 0,13038183 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02807057 0,13013062 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02807057 0,12988037 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02807057 0,12963108 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02807057 0,12938274 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02807057 0,12913535 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02807057 0,12888891 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02807057 0,12864341 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02807057 0,12839884 ! negative chemotaxis GO:0050919 14 5 0,000 0,02807057 0,1281552 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02807057 0,12791248 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02807057 0,12767068 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02807057 0,12742979 ! behavioral response to pain GO:0048266 9 5 0,000 0,02807057 0,12718981 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02807057 0,12695073 ! Notch receptor processing GO:0007220 8 5 0,000 0,02807057 0,12671255 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02807057 0,12647526 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02807057 0,12623886 ! micturition GO:0060073 9 5 0,000 0,02807057 0,12600334 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02807057 0,1257687 ! copulation GO:0007620 9 5 0,000 0,02807057 0,12553493 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02807057 0,12530202 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02807057 0,12506998 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02807057 0,1248388 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02807057 0,12460847 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02807057 0,12437899 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02807057 0,12415035 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02807057 0,12392255 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02807057 0,12369559 ! grooming behavior GO:0007625 6 5 0,000 0,02807057 0,12346945 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02807057 0,12324414 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02807057 0,12301965 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02807057 0,12279598 ! response to protozoan GO:0001562 10 5 0,000 0,02807057 0,12257312 ! lymph vessel development GO:0001945 10 5 0,000 0,02807057 0,12235107 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02807057 0,12212982 ! endochondral ossification GO:0001958 16 5 0,000 0,02807057 0,12190937 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02807057 0,12168971 ! parathyroid gland development GO:0060017 13 5 0,000 0,02807057 0,12147085 ! anagen GO:0042640 6 5 0,000 0,02807057 0,12125277 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02807057 0,12103547 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02807057 0,12081894 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02807057 0,1206032 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02807057 0,12038822 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02807057 0,120174 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02807057 0,11996055 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02807057 0,11974786 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02807057 0,11953591 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02807057 0,11932472 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02807057 0,11911427 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02807057 0,11890456 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02807057 0,11869559 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02807057 0,11848735 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02807057 0,11827984 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02807057 0,11807306 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02807057 0,117867 ! histidine catabolic process GO:0006548 6 5 0,000 0,02807057 0,11766166 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02807057 0,11745703 ! valine metabolic process GO:0006573 10 5 0,000 0,02807057 0,11725311 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02807057 0,1170499 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02807057 0,11684739 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02807057 0,11664558 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02807057 0,11644447 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02807057 0,11624405 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02807057 0,11604431 ! polyol catabolic process GO:0046174 7 5 0,000 0,02807057 0,11584527 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02807057 0,1156469 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02807057 0,11544921 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02807057 0,1152522 ! muscle cell migration GO:0014812 8 5 0,000 0,02807057 0,11505586 ! mitochondrial fission GO:0000266 8 5 0,000 0,02807057 0,11486019 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02807057 0,11466518 ! mRNA transcription GO:0009299 9 5 0,000 0,02807057 0,11447083 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02807057 0,11427714 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02807057 0,11408411 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02807057 0,11389172 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02807057 0,11369998 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02807057 0,11350889 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02807057 0,11331844 ! response to food GO:0032094 6 5 0,000 0,02807057 0,11312863 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02807057 0,11293945 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02807057 0,1127509 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02807057 0,11256298 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02807057 0,11237569 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02807057 0,11218902 ! forebrain neuron development GO:0021884 13 5 0,000 0,02807057 0,11200297 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02807057 0,11181753 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02807057 0,11163271 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02807057 0,1114485 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02807057 0,11126489 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02807057 0,11108189 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02807057 0,11089949 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02807057 0,11071769 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02807057 0,11053648 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02807057 0,11035587 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02807057 0,11017584 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02807057 0,1099964 ! basic amino acid transport GO:0015802 11 5 0,000 0,02807057 0,10981755 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02807057 0,10963927 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02807057 0,10946157 ! depyrimidination GO:0045008 10 5 0,000 0,02807057 0,10928445 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02807057 0,1091079 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02807057 0,10893192 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02807057 0,10875651 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02807057 0,10858166 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,02807057 0,10840737 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02807057 0,10823364 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02807057 0,10806046 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02807057 0,10788784 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02807057 0,10771577 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02807057 0,10754425 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02807057 0,10737328 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02807057 0,10720284 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02807057 0,10703295 ! response to arsenic GO:0046685 10 5 0,000 0,02807057 0,10686359 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02807057 0,10669477 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02807057 0,10652648 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02807057 0,10635872 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02807057 0,10619149 ! response to cadmium ion GO:0046686 7 5 0,000 0,02807057 0,10602479 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02807057 0,10585861 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02807057 0,10569294 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02807057 0,1055278 ! decidualization GO:0046697 11 5 0,000 0,02807057 0,10536317 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02807057 0,10519905 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02807057 0,10503544 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02807057 0,10487235 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02807057 0,10470975 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02807057 0,10454766 ! neural tube patterning GO:0021532 7 5 0,000 0,02807057 0,10438607 ! embryonic cleavage GO:0040016 6 5 0,000 0,02807057 0,10422498 ! peroxisome fission GO:0016559 5 5 0,000 0,02807057 0,10406439 ! histone demethylation GO:0016577 10 5 0,000 0,02807057 0,10390429 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02807057 0,10374469 ! mitotic recombination GO:0006312 9 5 0,000 0,02807057 0,10358557 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02807057 0,10342694 ! metaphase plate congression GO:0051310 7 5 0,000 0,02807057 0,10326879 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02807057 0,10311113 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02807057 0,10295395 ! enteric nervous system development GO:0048484 8 5 0,000 0,02807057 0,10279725 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02807057 0,10264102 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02807057 0,10248527 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02807057 0,10232999 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02807057 0,10217517 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02807057 0,10202083 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02807057 0,10186695 ! plasminogen activation GO:0031639 5 5 0,000 0,02807057 0,10171354 ! B cell homeostasis GO:0001782 13 5 0,000 0,02807057 0,10156059 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02807057 0,10140809 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02807057 0,10125606 ! metaphase GO:0051323 8 5 0,000 0,02807057 0,10110448 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02807057 0,10095335 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02807057 0,10080267 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02807057 0,10065244 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02807057 0,10050266 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02807057 0,10035333 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02807057 0,10020444 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02807057 0,10005599 ! response to redox state GO:0051775 5 5 0,000 0,02807057 0,09990797 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02807057 0,0997604 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02807057 0,09961326 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02807057 0,09946655 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02807057 0,09932028 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02807057 0,09917443 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02807057 0,09902902 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02807057 0,09888403 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02807057 0,09873946 ! striatum development GO:0021756 9 5 0,000 0,02807057 0,09859531 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02807057 0,09845159 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02807057 0,09830828 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02807057 0,09816539 ! glial cell migration GO:0008347 11 5 0,000 0,02807057 0,09802292 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02807057 0,09788086 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02807057 0,0977392 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02807057 0,09759796 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02807057 0,09745713 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02807057 0,0973167 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02807057 0,09717668 ! neuroprotection GO:0043526 6 5 0,000 0,02807057 0,09703705 ! neural plate development GO:0001840 8 5 0,000 0,02807057 0,09689783 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02807057 0,09675901 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02807057 0,09662059 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02807057 0,09648256 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02807057 0,09634492 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02807057 0,09620768 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02807057 0,09607083 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02807057 0,09593436 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02807057 0,09579828 ! spindle assembly GO:0051225 6 5 0,000 0,02807057 0,09566259 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02807057 0,09552728 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02807057 0,09539236 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02807057 0,09525781 ! drug metabolic process GO:0017144 6 5 0,000 0,02807057 0,09512365 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02807057 0,09498986 ! organ regeneration GO:0031100 7 5 0,000 0,02807057 0,09485645 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02807057 0,09472341 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02807057 0,09459074 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02807057 0,09445845 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,02817384 0,09467356 ! endosome transport GO:0016197 108 47 1,000 0,02931812 0,09838131 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,02931812 0,09824429 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,02931812 0,09810765 ! JNK cascade GO:0007254 91 47 1,000 0,02931812 0,09797139 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,02931812 0,09783551 ! methylation GO:0032259 90 47 1,000 0,02931812 0,0977 ! cellular component disassembly GO:0022411 86 48 1,000 0,0304807 0,10143371 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,0304807 0,10129361 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,0304807 0,10115389 ! activation of caspase activity GO:0006919 84 48 1,000 0,0304807 0,10101456 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 0,03166135 0,10478295 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,03285981 0,10859988 ! neuromuscular process GO:0050905 99 50 1,000 0,03285981 0,10845091 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,03285981 0,10830235 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,03285981 0,10815419 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03358996 0,11040635 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03358996 0,11025573 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03358996 0,11010551 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03358996 0,10995571 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03358996 0,10980631 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03358996 0,10965732 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03358996 0,10950874 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03358996 0,10936055 ! sleep GO:0030431 13 6 0,000 0,03358996 0,10921277 ! response to oxygen radical GO:0000305 11 6 0,000 0,03358996 0,10906538 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03358996 0,10891839 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03358996 0,1087718 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03358996 0,1086256 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03358996 0,1084798 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03358996 0,10833438 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03358996 0,10818935 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03358996 0,10804472 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03358996 0,10790046 ! male meiosis GO:0007140 7 6 0,000 0,03358996 0,1077566 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03358996 0,10761311 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03358996 0,10747001 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03358996 0,10732729 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03358996 0,10718494 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03358996 0,10704298 ! malate metabolic process GO:0006108 11 6 0,000 0,03358996 0,10690139 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03358996 0,10676017 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03358996 0,10661932 ! protein refolding GO:0042026 15 6 0,000 0,03358996 0,10647885 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03358996 0,10633875 ! opsonization GO:0008228 8 6 0,000 0,03358996 0,10619901 ! mating behavior GO:0007617 7 6 0,000 0,03358996 0,10605964 ! neuron remodeling GO:0016322 15 6 0,000 0,03358996 0,10592064 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03358996 0,105782 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03358996 0,10564372 ! equilibrioception GO:0050957 14 6 0,000 0,03358996 0,10550581 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03358996 0,10536825 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03358996 0,10523105 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03358996 0,10509421 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03358996 0,10495772 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03358996 0,10482159 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03358996 0,10468581 ! toxin metabolic process GO:0009404 11 6 0,000 0,03358996 0,10455038 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03358996 0,10441531 ! nuclear migration GO:0007097 12 6 0,000 0,03358996 0,10428058 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03358996 0,1041462 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03358996 0,10401216 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03358996 0,10387847 ! thymic T cell selection GO:0045061 12 6 0,000 0,03358996 0,10374512 ! protein lipoylation GO:0009249 10 6 0,000 0,03358996 0,10361211 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03358996 0,10347945 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03358996 0,10334712 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03358996 0,10321513 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03358996 0,10308348 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03358996 0,10295216 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03358996 0,10282118 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03358996 0,10269053 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03358996 0,10256021 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03358996 0,10243022 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03358996 0,10230057 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03358996 0,10217124 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03358996 0,10204223 ! urea metabolic process GO:0019627 7 6 0,000 0,03358996 0,10191355 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03358996 0,1017852 ! neutrophil activation GO:0042119 8 6 0,000 0,03358996 0,10165717 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03358996 0,10152946 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03358996 0,10140207 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03358996 0,101275 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03358996 0,10114824 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03358996 0,10102181 ! neuron apoptosis GO:0051402 9 6 0,000 0,03358996 0,10089569 ! nucleoside salvage GO:0043174 9 6 0,000 0,03358996 0,10076988 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03358996 0,10064439 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03358996 0,10051921 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03358996 0,10039434 ! carnitine transport GO:0015879 10 6 0,000 0,03358996 0,10026979 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03358996 0,10014554 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03358996 0,10002159 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03358996 0,09989796 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03358996 0,09977463 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03358996 0,0996516 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03358996 0,09952888 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03358996 0,09940645 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03358996 0,09928433 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03358996 0,09916251 ! establishment of spindle localization GO:0051293 12 6 0,000 0,03358996 0,09904099 GO:0051653|spindle localization, ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03358996 0,09891976 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03358996 0,09879884 ! neural nucleus development GO:0048857 14 6 0,000 0,03358996 0,0986782 ! response to UV-C GO:0010225 11 6 0,000 0,03358996 0,09855786 ! astrocyte development GO:0014002 15 6 0,000 0,03358996 0,09843782 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03358996 0,09831806 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03358996 0,0981986 ! interaction with symbiont GO:0051702 13 6 0,000 0,03358996 0,09807943 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03358996 0,09796054 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03358996 0,09784195 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03358996 0,09772364 ! response to copper ion GO:0046688 10 6 0,000 0,03358996 0,09760561 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03358996 0,09748787 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03358996 0,09737042 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03358996 0,09725325 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03358996 0,09713636 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03358996 0,09701974 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03358996 0,09690341 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03358996 0,09678736 ! hair follicle maturation GO:0048820 7 6 0,000 0,03358996 0,09667159 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03358996 0,09655609 ! Schwann cell development GO:0014044 15 6 0,000 0,03358996 0,09644087 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03358996 0,09632592 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03358996 0,09621125 ! subpallium development GO:0021544 10 6 0,000 0,03358996 0,09609685 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03358996 0,09598272 ! histone ubiquitination GO:0016574 8 6 0,000 0,03358996 0,09586886 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03358996 0,09575527 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03358996 0,09564195 ! G2 phase GO:0051319 16 6 0,000 0,03358996 0,0955289 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03358996 0,09541611 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03358996 0,09530359 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03358996 0,09519134 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03358996 0,09507935 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03358996 0,09496762 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03358996 0,09485616 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03358996 0,09474496 ! receptor internalization GO:0031623 10 6 0,000 0,03358996 0,09463401 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03358996 0,09452333 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03358996 0,09441291 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03358996 0,09430274 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03358996 0,09419283 ! protein deubiquitination GO:0016579 14 6 0,000 0,03358996 0,09408318 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03358996 0,09397378 ! protein destabilization GO:0031648 9 6 0,000 0,03358996 0,09386463 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03358996 0,09375574 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03358996 0,0936471 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03358996 0,09353871 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03358996 0,09343058 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03358996 0,09332269 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03358996 0,09321505 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03358996 0,09310766 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03358996 0,09300051 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03358996 0,09289362 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03358996 0,09278697 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03358996 0,09268056 ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03358996 0,0925744 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03358996 0,09246848 ! catecholamine transport GO:0051937 9 6 0,000 0,03358996 0,0923628 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03358996 0,09225736 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03358996 0,09215216 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03358996 0,09204721 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03358996 0,09194249 ! maternal placenta development GO:0001893 12 6 0,000 0,03358996 0,09183801 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03358996 0,09173377 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03358996 0,09162976 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03358996 0,09152599 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03358996 0,09142245 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03358996 0,09131915 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03358996 0,09121608 ! positive regulation of binding GO:0051099 78 51 1,000 0,03407587 0,09243126 ! chromatin remodeling GO:0006338 109 51 1,000 0,03407587 0,09232718 ! regulation of cell shape GO:0008360 125 51 1,000 0,03407587 0,09222332 ! positive regulation of growth GO:0045927 90 52 1,000 0,03530927 0,09545404 ! cartilage development GO:0051216 90 52 1,000 0,03530927 0,09534691 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 1,000 0,03655978 0,09861304 ! cell maturation GO:0048469 100 53 1,000 0,03655978 0,09850261 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,03655978 0,09839243 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,03782718 0,1016896 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,03782718 0,10157611 ! cell recognition GO:0008037 85 54 1,000 0,03782718 0,10146287 ! heterocycle catabolic process GO:0046700 85 54 1,000 0,03782718 0,10134988 ! tRNA transcription GO:0009304 14 7 0,000 0,03907819 0,10458524 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03907819 0,10446903 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03907819 0,10435309 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03907819 0,1042374 ! regulation of helicase activity GO:0051095 15 7 0,000 0,03907819 0,10412196 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03907819 0,10400678 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03907819 0,10389186 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03907819 0,10377719 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03907819 0,10366277 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03907819 0,1035486 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03907819 0,10343469 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03907819 0,10332102 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03907819 0,10320761 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03907819 0,10309444 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03907819 0,10298152 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03907819 0,10286885 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03907819 0,10275643 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,03907819 0,10264425 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03907819 0,10253231 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03907819 0,10242062 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03907819 0,10230917 ! glycolipid transport GO:0046836 10 7 0,000 0,03907819 0,10219797 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03907819 0,102087 GO:0051923|sulfation, ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03907819 0,10197628 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03907819 0,1018658 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03907819 0,10175555 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03907819 0,10164555 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03907819 0,10153578 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03907819 0,10142625 ! pericardium development GO:0060039 14 7 0,000 0,03907819 0,10131695 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03907819 0,10120789 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03907819 0,10109907 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03907819 0,10099047 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03907819 0,10088211 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03907819 0,10077399 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03907819 0,10066609 ! lipoprotein transport GO:0042953 14 7 0,000 0,03907819 0,10055843 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03907819 0,10045099 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03907819 0,10034379 ! rhythmic behavior GO:0007622 15 7 0,000 0,03907819 0,10023681 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03907819 0,10013006 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03907819 0,10002354 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03907819 0,09991725 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03907819 0,09981118 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03907819 0,09970533 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03907819 0,09959971 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03907819 0,09949432 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03907819 0,09938914 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03907819 0,09928419 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03907819 0,09917946 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03907819 0,09907495 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03907819 0,09897066 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03907819 0,09886659 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03907819 0,09876274 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03907819 0,09865911 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03907819 0,09855569 ! adrenal gland development GO:0030325 17 7 0,000 0,03907819 0,09845249 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03907819 0,09834951 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03907819 0,09824674 ! ovulation GO:0030728 9 7 0,000 0,03907819 0,09814419 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03907819 0,09804185 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03907819 0,09793972 ! microtubule nucleation GO:0007020 20 7 0,000 0,03907819 0,09783781 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03907819 0,0977361 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03907819 0,09763461 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03907819 0,09753333 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03907819 0,09743226 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03907819 0,0973314 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03907819 0,09723075 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03907819 0,0971303 ! galactose metabolic process GO:0006012 13 7 0,000 0,03907819 0,09703006 ! vesicle fusion GO:0006906 17 7 0,000 0,03907819 0,09693003 ! response to dietary excess GO:0002021 8 7 0,000 0,03907819 0,09683021 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03907819 0,09673059 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03907819 0,09663117 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03907819 0,09653196 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03907819 0,09643295 ! organ growth GO:0035265 15 7 0,000 0,03907819 0,09633415 ! nucleoside transport GO:0015858 8 7 0,000 0,03907819 0,09623555 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03907819 0,09613715 ! parturition GO:0007567 14 7 0,000 0,03907819 0,09603895 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03907819 0,09594095 ! rRNA modification GO:0000154 14 7 0,000 0,03907819 0,09584315 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03907819 0,09574555 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03907819 0,09564815 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03907819 0,09555095 ! macrophage differentiation GO:0030225 11 7 0,000 0,03907819 0,09545394 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03907819 0,09535713 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03907819 0,09526052 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03907819 0,0951641 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03907819 0,09506788 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,03907819 0,09497185 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03907819 0,09487601 ! fibrinolysis GO:0042730 10 7 0,000 0,03907819 0,09478037 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,03907819 0,09468493 ! eating behavior GO:0042755 7 7 0,000 0,03907819 0,09458967 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03907819 0,0944946 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03907819 0,09439973 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03907819 0,09430505 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03907819 0,09421055 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03907819 0,09411625 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03907819 0,09402213 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03907819 0,0939282 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03907819 0,09383446 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03907819 0,09374091 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03907819 0,09364754 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03907819 0,09355436 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03907819 0,09346136 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03907819 0,09336855 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03907819 0,09327592 ! regulation of meiosis GO:0040020 12 7 0,000 0,03907819 0,09318348 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03907819 0,09309122 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03907819 0,09299914 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03907819 0,09290724 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03907819 0,09281553 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03907819 0,09272399 ! transcription termination GO:0006353 13 7 0,000 0,03907819 0,09263264 ! response to tumor cell GO:0002347 13 7 0,000 0,03907819 0,09254147 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03907819 0,09245047 ! anaphase GO:0051322 17 7 0,000 0,03907819 0,09235966 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03907819 0,09226902 ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03907819 0,09217856 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03907819 0,09208828 ! diuresis GO:0030146 12 7 0,000 0,03907819 0,09199817 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03907819 0,09190824 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03907819 0,09181849 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03907819 0,09172891 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03907819 0,0916395 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03907819 0,09155027 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03907819 0,09146122 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03907819 0,09137233 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03907819 0,09128362 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03907819 0,09119508 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03907819 0,09110672 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03907819 0,09101852 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03907819 0,09093049 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03907819 0,09084264 ! lymph node development GO:0048535 10 7 0,000 0,03907819 0,09075495 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03907819 0,09066744 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03907819 0,09058009 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03907819 0,09049291 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03907819 0,09040589 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03907819 0,09031905 ! adult feeding behavior GO:0008343 9 7 0,000 0,03907819 0,09023237 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03907819 0,09014586 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03907819 0,09005951 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03907819 0,08997333 ! muscle adaptation GO:0043500 14 7 0,000 0,03907819 0,08988731 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03907819 0,08980146 ! retina homeostasis GO:0001895 12 7 0,000 0,03907819 0,08971577 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03907819 0,08963025 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03907819 0,08954489 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03907819 0,08945969 ! protein prenylation GO:0018342 18 7 0,000 0,03907819 0,08937465 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03907819 0,08928977 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03907819 0,08920506 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03907819 0,0891205 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,03911123 0,08911139 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,03911123 0,08902708 ! aging GO:0007568 103 55 1,000 0,03911123 0,08894294 ! heart morphogenesis GO:0003007 97 55 1,000 0,03911123 0,08885895 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,04041171 0,09172696 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,04172839 0,09462631 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,04172839 0,09453721 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,04306105 0,09746462 ! adult behavior GO:0030534 99 58 1,000 0,04306105 0,09737302 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,04306105 0,09728159 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,04440947 0,10023375 ! establishment of organelle localization GO:0051656 109 59 1,000 0,04440947 0,10013981 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04453544 0,10032983 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04453544 0,10023598 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04453544 0,1001423 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04453544 0,1000488 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04453544 0,09995547 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04453544 0,09986231 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04453544 0,09976933 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04453544 0,09967652 ! meiotic prophase I GO:0007128 13 8 0,000 0,04453544 0,09958389 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04453544 0,09949142 ! oligopeptide transport GO:0006857 15 8 0,000 0,04453544 0,09939913 ! UTP metabolic process GO:0046051 8 8 0,000 0,04453544 0,09930701 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04453544 0,09921506 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04453544 0,09912328 GO:0046457|prostanoid biosynthetic process, ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04453544 0,09903166 ! succinate metabolic process GO:0006105 14 8 0,000 0,04453544 0,09894022 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04453544 0,09884895 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04453544 0,09875784 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04453544 0,09866691 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04453544 0,09857614 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04453544 0,09848553 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04453544 0,0983951 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04453544 0,09830483 ! reflex GO:0060004 16 8 0,000 0,04453544 0,09821472 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04453544 0,09812478 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04453544 0,09803501 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04453544 0,09794539 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04453544 0,09785595 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04453544 0,09776666 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04453544 0,09767754 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04453544 0,09758858 ! pigment granule organization GO:0048753 16 8 0,000 0,04453544 0,09749978 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04453544 0,09741115 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04453544 0,09732267 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04453544 0,09723436 ! histidine metabolic process GO:0006547 16 8 0,000 0,04453544 0,0971462 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04453544 0,09705821 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04453544 0,09697037 ! ER overload response GO:0006983 12 8 0,000 0,04453544 0,0968827 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04453544 0,09679518 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04453544 0,09670782 ! melanin metabolic process GO:0006582 15 8 0,000 0,04453544 0,09662061 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04453544 0,09653357 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04453544 0,09644668 ! macrophage activation GO:0042116 12 8 0,000 0,04453544 0,09635995 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04453544 0,09627337 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04453544 0,09618695 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04453544 0,09610068 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04453544 0,09601457 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04453544 0,09592861 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04453544 0,09584281 ! osteoblast development GO:0002076 16 8 0,000 0,04453544 0,09575716 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04453544 0,09567166 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04453544 0,09558632 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04453544 0,09550112 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04453544 0,09541608 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04453544 0,09533119 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04453544 0,09524645 ! response to UV-B GO:0010224 16 8 0,000 0,04453544 0,09516187 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04453544 0,09507743 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04453544 0,09499314 ! intermediate filament organization GO:0045109 12 8 0,000 0,04453544 0,094909 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04453544 0,09482501 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04453544 0,09474117 ! cellular extravasation GO:0045123 12 8 0,000 0,04453544 0,09465747 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04453544 0,09457393 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04453544 0,09449053 ! response to antibiotic GO:0046677 11 8 0,000 0,04453544 0,09440728 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04453544 0,09432417 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04453544 0,09424121 ! response to tropane GO:0014073 15 8 0,000 0,04453544 0,0941584 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04453544 0,09407573 ! melanosome transport GO:0032402 13 8 0,000 0,04453544 0,09399321 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04453544 0,09391083 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04453544 0,0938286 ! mast cell activation GO:0045576 14 8 0,000 0,04453544 0,09374651 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04453544 0,09366456 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04453544 0,09358276 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04453544 0,0935011 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04453544 0,09341958 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04453544 0,09333821 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04453544 0,09325697 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04453544 0,09317588 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04453544 0,09309493 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04453544 0,09301412 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04453544 0,09293344 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04453544 0,09285291 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04453544 0,09277252 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04453544 0,09269227 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04453544 0,09261215 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04453544 0,09253218 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04453544 0,09245234 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04453544 0,09237264 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04453544 0,09229308 ! hormone catabolic process GO:0042447 17 8 0,000 0,04453544 0,09221365 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04453544 0,09213436 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04453544 0,09205521 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04453544 0,09197619 ! ATP catabolic process GO:0006200 11 8 0,000 0,04453544 0,09189731 ! blastocyst growth GO:0001832 19 8 0,000 0,04453544 0,09181856 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04453544 0,09173995 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04453544 0,09166147 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04453544 0,09158313 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04453544 0,09150492 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04453544 0,09142684 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04453544 0,0913489 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04453544 0,09127109 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04453544 0,09119341 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04453544 0,09111587 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04453544 0,09103845 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04453544 0,09096117 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04453544 0,09088402 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04453544 0,090807 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04453544 0,09073011 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04453544 0,09065335 ! nucleoside metabolic process GO:0009116 81 60 1,000 0,04577342 0,09309454 ! camera-type eye development GO:0043010 116 60 1,000 0,04577342 0,09301591 ! kidney development GO:0001822 122 60 1,000 0,04577342 0,09293742 ! mesoderm development GO:0007498 119 61 1,000 0,04715269 0,09565713 ! viral reproductive process GO:0022415 126 62 1,000 0,04854706 0,09840288 ! gonad development GO:0008406 98 62 1,000 0,04854706 0,09832005 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,04854706 0,09823736 ! nucleoside monophosphate metabolic process GO:0009123 107 63 1,000 0,04995632 0,10100412 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,04995632 0,10091932 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,04995632 0,10083465 ! axon extension GO:0048675 15 9 0,000 0,04996187 0,10076132 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,04996187 0,10067693 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04996187 0,10059268 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,04996187 0,10050858 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04996187 0,10042461 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04996187 0,10034078 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04996187 0,10025709 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04996187 0,10017355 ! phosphate transport GO:0006817 19 9 0,000 0,04996187 0,10009014 ! reproductive behavior GO:0019098 19 9 0,000 0,04996187 0,10000687 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04996187 0,09992374 ! CTP metabolic process GO:0046036 9 9 0,000 0,04996187 0,09984074 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,04996187 0,09975789 ! GTP metabolic process GO:0046039 9 9 0,000 0,04996187 0,09967517 ! RNA methylation GO:0001510 15 9 0,000 0,04996187 0,09959259 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04996187 0,09951015 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04996187 0,09942784 ! artery development GO:0060840 24 9 0,000 0,04996187 0,09934567 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,04996187 0,09926363 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04996187 0,09918173 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,04996187 0,09909996 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,04996187 0,09901833 ! chemosensory behavior GO:0007635 20 9 0,000 0,04996187 0,09893684 ! microtubule bundle formation GO:0001578 21 9 0,000 0,04996187 0,09885547 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,04996187 0,09877424 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,04996187 0,09869315 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04996187 0,09861219 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04996187 0,09853136 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04996187 0,09845066 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04996187 0,09837009 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04996187 0,09828966 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04996187 0,09820936 ! protein targeting to ER GO:0045047 22 9 0,000 0,04996187 0,09812919 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04996187 0,09804915 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,04996187 0,09796924 ! T cell selection GO:0045058 23 9 0,000 0,04996187 0,09788946 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04996187 0,09780981 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04996187 0,09773029 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,04996187 0,0976509 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04996187 0,09757164 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04996187 0,0974925 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04996187 0,0974135 ! mannose metabolic process GO:0006013 13 9 0,000 0,04996187 0,09733462 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04996187 0,09725587 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04996187 0,09717725 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04996187 0,09709875 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04996187 0,09702038 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04996187 0,09694214 ! ruffle organization GO:0031529 15 9 0,000 0,04996187 0,09686403 ! retinol metabolic process GO:0042572 18 9 0,000 0,04996187 0,09678604 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04996187 0,09670817 ! behavioral fear response GO:0001662 22 9 0,000 0,04996187 0,09663043 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04996187 0,09655282 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04996187 0,09647533 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04996187 0,09639796 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,04996187 0,09632072 ! oligodendrocyte development GO:0014003 10 9 0,000 0,04996187 0,0962436 ! segment specification GO:0007379 13 9 0,000 0,04996187 0,0961666 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04996187 0,09608973 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04996187 0,09601298 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04996187 0,09593636 ! response to amine stimulus GO:0014075 13 9 0,000 0,04996187 0,09585985 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04996187 0,09578347 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04996187 0,09570721 ! erythrocyte development GO:0048821 15 9 0,000 0,04996187 0,09563107 ! gas homeostasis GO:0033483 16 9 0,000 0,04996187 0,09555505 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04996187 0,09547915 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,04996187 0,09540338 ! renal water homeostasis GO:0003091 14 9 0,000 0,04996187 0,09532772 ! postreplication repair GO:0006301 22 9 0,000 0,04996187 0,09525218 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04996187 0,09517677 ! icosanoid secretion GO:0032309 15 9 0,000 0,04996187 0,09510147 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,04996187 0,09502629 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04996187 0,09495123 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04996187 0,09487629 ! regulation of cell division GO:0051302 15 9 0,000 0,04996187 0,09480146 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04996187 0,09472676 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04996187 0,09465217 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04996187 0,0945777 ! sterol catabolic process GO:0016127 11 9 0,000 0,04996187 0,09450335 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04996187 0,09442911 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04996187 0,09435499 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,04996187 0,09428099 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,04996187 0,0942071 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,04996187 0,09413333 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,04996187 0,09405967 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04996187 0,09398613 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04996187 0,0939127 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04996187 0,09383939 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04996187 0,09376619 ! purine base metabolic process GO:0006144 21 9 0,000 0,04996187 0,09369311 ! pigment granule transport GO:0051904 17 9 0,000 0,04996187 0,09362014 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04996187 0,09354728 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,04996187 0,09347454 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04996187 0,09340191 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04996187 0,09332939 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04996187 0,09325699 ! mitochondrion localization GO:0051646 15 9 0,000 0,04996187 0,09318469 ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 0,05281867 0,09843665 ! myeloid cell differentiation GO:0030099 111 65 1,000 0,05281867 0,09836046 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,05427133 0,10098749 ! developmental maturation GO:0021700 116 66 1,000 0,05427133 0,10090945 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05535766 0,10284983 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05535766 0,10277047 ! synapsis GO:0007129 13 10 0,000 0,05535766 0,10269124 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05535766 0,10261212 ! N-glycan processing GO:0006491 20 10 0,000 0,05535766 0,10253313 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05535766 0,10245426 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,05535766 0,10237551 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05535766 0,10229688 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05535766 0,10221837 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,05535766 0,10213998 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05535766 0,10206171 GO:0048200|Golgi transport vesicle coating, ! androgen metabolic process GO:0008209 17 10 0,000 0,05535766 0,10198356 ! phospholipid efflux GO:0033700 16 10 0,000 0,05535766 0,10190553 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05535766 0,10182762 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05535766 0,10174983 ! pathogenesis GO:0009405 13 10 0,000 0,05535766 0,10167216 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05535766 0,10159461 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05535766 0,10151717 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05535766 0,10143986 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,05535766 0,10136266 ! endoderm development GO:0007492 16 10 0,000 0,05535766 0,10128558 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05535766 0,10120861 ! arginine catabolic process GO:0006527 13 10 0,000 0,05535766 0,10113176 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05535766 0,10105503 ! proline metabolic process GO:0006560 13 10 0,000 0,05535766 0,10097842 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05535766 0,10090192 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,05535766 0,10082554 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05535766 0,10074927 ! V(D)J recombination GO:0033151 28 10 0,000 0,05535766 0,10067312 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05535766 0,10059708 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05535766 0,10052116 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05535766 0,10044535 ! B cell proliferation GO:0042100 18 10 0,000 0,05535766 0,10036966 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05535766 0,10029408 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05535766 0,10021861 ! multicellular organism growth GO:0035264 18 10 0,000 0,05535766 0,10014326 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05535766 0,10006802 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05535766 0,09999289 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05535766 0,09991788 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05535766 0,09984298 ! macroautophagy GO:0016236 17 10 0,000 0,05535766 0,09976819 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05535766 0,09969351 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05535766 0,09961895 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05535766 0,09954449 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05535766 0,09947015 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,05535766 0,09939592 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05535766 0,0993218 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05535766 0,09924779 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05535766 0,09917389 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05535766 0,0991001 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05535766 0,09902642 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,05535766 0,09895285 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05535766 0,09887939 ! response to dsRNA GO:0043331 20 10 0,000 0,05535766 0,09880603 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05535766 0,09873279 ! melanosome localization GO:0032400 16 10 0,000 0,05535766 0,09865965 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05535766 0,09858663 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05535766 0,09851371 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05535766 0,0984409 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05535766 0,09836819 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05535766 0,0982956 ! mRNA cleavage GO:0006379 17 10 0,000 0,05535766 0,09822311 ! protein sumoylation GO:0016925 15 10 0,000 0,05535766 0,09815072 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05535766 0,09807845 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05535766 0,09800628 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05535766 0,09793422 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05535766 0,09786226 ! salivary gland development GO:0007431 27 10 0,000 0,05535766 0,09779041 ! prophase GO:0051324 15 10 0,000 0,05535766 0,09771866 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05535766 0,09764702 ! apical protein localization GO:0045176 15 10 0,000 0,05535766 0,09757548 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05535766 0,09750405 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05535766 0,09743272 ! midbrain development GO:0030901 13 10 0,000 0,05535766 0,0973615 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05535766 0,09729038 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05535766 0,09721937 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05535766 0,09714846 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05535766 0,09707765 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05535766 0,09700694 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05535766 0,09693634 ! detection of calcium ion GO:0005513 23 10 0,000 0,05535766 0,09686584 ! oocyte development GO:0048599 17 10 0,000 0,05535766 0,09679545 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05535766 0,09672515 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05535766 0,09665496 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05535766 0,09658487 ! activation of innate immune response GO:0002218 12 10 0,000 0,05535766 0,09651488 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05535766 0,09644499 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05535766 0,0963752 ! response to nicotine GO:0035094 20 10 0,000 0,05535766 0,09630552 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05535766 0,09623593 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05535766 0,09616645 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,05573805 0,0967574 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 1,000 0,05573805 0,09668764 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,05573805 0,09661798 ! adaptive immune response GO:0002250 119 67 1,000 0,05573805 0,09654842 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! amino acid transport GO:0006865 125 68 1,000 0,05721862 0,09904173 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,05721862 0,09897053 ! viral reproduction GO:0016032 134 68 1,000 0,05721862 0,09889943 ! regulation of lipase activity GO:0060191 130 68 1,000 0,05721862 0,09882843 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,05871284 0,10133651 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,05871284 0,10126387 ! coenzyme biosynthetic process GO:0009108 102 69 1,000 0,05871284 0,10119133 ! respiratory burst GO:0045730 17 11 0,000 0,06072299 0,10458089 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06072299 0,10450608 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06072299 0,10443138 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06072299 0,10435679 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06072299 0,1042823 ! thyroid gland development GO:0030878 26 11 0,000 0,06072299 0,10420792 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06072299 0,10413365 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06072299 0,10405948 ! response to pain GO:0048265 24 11 0,000 0,06072299 0,10398541 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,06072299 0,10391145 ! T cell proliferation GO:0042098 26 11 0,000 0,06072299 0,1038376 ! bone resorption GO:0045453 16 11 0,000 0,06072299 0,10376385 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06072299 0,10369021 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06072299 0,10361667 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06072299 0,10354324 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06072299 0,1034699 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06072299 0,10339668 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06072299 0,10332355 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06072299 0,10325053 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06072299 0,10317762 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,06072299 0,1031048 ! lipid digestion GO:0044241 18 11 0,000 0,06072299 0,10303209 ! UV protection GO:0009650 19 11 0,000 0,06072299 0,10295948 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,06072299 0,10288698 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06072299 0,10281457 ! temperature homeostasis GO:0001659 17 11 0,000 0,06072299 0,10274227 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06072299 0,10267007 ! negative regulation of ossification GO:0030279 26 11 0,000 0,06072299 0,10259797 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,06072299 0,10252597 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06072299 0,10245407 ! regulation of organ growth GO:0046620 13 11 0,000 0,06072299 0,10238227 ! pigment granule localization GO:0051875 20 11 0,000 0,06072299 0,10231058 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06072299 0,10223898 ! vasoconstriction GO:0042310 18 11 0,000 0,06072299 0,10216749 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06072299 0,10209609 ! embryonic axis specification GO:0000578 18 11 0,000 0,06072299 0,10202479 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06072299 0,1019536 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06072299 0,1018825 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06072299 0,1018115 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06072299 0,1017406 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06072299 0,1016698 ! zymogen activation GO:0031638 15 11 0,000 0,06072299 0,1015991 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06072299 0,1015285 ! neuroblast proliferation GO:0007405 24 11 0,000 0,06072299 0,10145799 ! nucleosome positioning GO:0016584 15 11 0,000 0,06072299 0,10138758 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06072299 0,10131727 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06072299 0,10124706 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06072299 0,10117694 ! acid secretion GO:0046717 18 11 0,000 0,06072299 0,10110692 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06072299 0,101037 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06072299 0,10096718 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06072299 0,10089745 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06072299 0,10082782 ! oocyte differentiation GO:0009994 18 11 0,000 0,06072299 0,10075828 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06072299 0,10068884 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,06072299 0,10061949 ! cholesterol efflux GO:0033344 19 11 0,000 0,06072299 0,10055024 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06072299 0,10048109 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06072299 0,10041203 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,06072299 0,10034307 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,06072299 0,1002742 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06072299 0,10020542 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06072299 0,10013674 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06072299 0,10006815 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06072299 0,09999966 ! defense response to fungus GO:0050832 13 11 0,000 0,06072299 0,09993126 ! developmental induction GO:0031128 19 11 0,000 0,06072299 0,09986296 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,06072299 0,09979474 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06072299 0,09972662 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06072299 0,0996586 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06072299 0,09959066 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06072299 0,09952282 ! nucleus localization GO:0051647 19 11 0,000 0,06072299 0,09945507 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06072299 0,09938742 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,06174141 0,10098562 ! regulation of caspase activity GO:0043281 122 72 1,000 0,06327537 0,10342429 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,06327537 0,10335407 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,06327537 0,10328396 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,06327537 0,10321393 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06605801 0,10767993 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06605801 0,10760703 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06605801 0,10753422 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06605801 0,10746152 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06605801 0,10738891 ! mating GO:0007618 17 12 0,000 0,06605801 0,1073164 ! protein complex disassembly GO:0043241 27 12 0,000 0,06605801 0,10724398 GO:0043624|cellular protein complex disassembly, ! hippocampus development GO:0021766 26 12 0,000 0,06605801 0,10717167 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06605801 0,10709945 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06605801 0,10702733 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,06605801 0,10695531 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06605801 0,10688338 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06605801 0,10681155 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06605801 0,10673981 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06605801 0,10666818 ! drug transport GO:0015893 16 12 0,000 0,06605801 0,10659664 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06605801 0,10652519 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06605801 0,10645384 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06605801 0,10638259 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06605801 0,10631143 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06605801 0,10624036 ! forebrain cell migration GO:0021885 21 12 0,000 0,06605801 0,10616939 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06605801 0,10609852 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06605801 0,10602774 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06605801 0,10595706 ! entry into host cell GO:0030260 32 12 0,000 0,06605801 0,10588646 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,06605801 0,10581597 ! monoamine transport GO:0015844 18 12 0,000 0,06605801 0,10574556 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06605801 0,10567525 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06605801 0,10560504 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06605801 0,10553492 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06605801 0,10546489 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06605801 0,10539495 ! protein homotetramerization GO:0051289 21 12 0,000 0,06605801 0,1053251 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06605801 0,10525535 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06605801 0,10518569 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06605801 0,10511613 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06605801 0,10504665 ! fucose catabolic process GO:0019317 22 12 0,000 0,06605801 0,10497727 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06605801 0,10490798 ! histone methylation GO:0016571 26 12 0,000 0,06605801 0,10483878 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06605801 0,10476967 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06605801 0,10470065 ! gland morphogenesis GO:0022612 29 12 0,000 0,06605801 0,10463172 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,06605801 0,10456288 ! T cell homeostasis GO:0043029 25 12 0,000 0,06605801 0,10449414 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06605801 0,10442548 ! spleen development GO:0048536 22 12 0,000 0,06605801 0,10435692 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06605801 0,10428844 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06605801 0,10422005 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06605801 0,10415176 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06605801 0,10408355 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06605801 0,10401543 ! response to cold GO:0009409 17 12 0,000 0,06605801 0,10394741 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06605801 0,10387947 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06605801 0,10381162 ! exocytosis GO:0006887 133 74 1,000 0,06638167 0,10425215 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,06638167 0,10418414 ! eye development GO:0001654 143 74 1,000 0,06638167 0,10411623 ! organelle localization GO:0051640 136 74 1,000 0,06638167 0,1040484 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,06795362 0,10644297 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,06953784 0,10885364 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,07113416 0,1112801 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07136292 0,11156542 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07136292 0,11149297 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07136292 0,11142062 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07136292 0,11134836 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,07136292 0,1112762 ! lipid localization GO:0010876 28 13 0,000 0,07136292 0,11120413 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,07136292 0,11113215 ! organelle fusion GO:0048284 32 13 0,000 0,07136292 0,11106027 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07136292 0,11098848 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07136292 0,11091678 ! endocrine pancreas development GO:0031018 22 13 0,000 0,07136292 0,11084518 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07136292 0,11077366 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07136292 0,11070224 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07136292 0,11063091 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07136292 0,11055968 ! methionine metabolic process GO:0006555 27 13 0,000 0,07136292 0,11048853 ! plasma membrane organization GO:0007009 24 13 0,000 0,07136292 0,11041748 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07136292 0,11034652 ! Golgi organization GO:0007030 24 13 0,000 0,07136292 0,11027564 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,07136292 0,11020486 ! response to X-ray GO:0010165 25 13 0,000 0,07136292 0,11013417 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07136292 0,11006358 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,07136292 0,10999307 ! exocrine system development GO:0035272 32 13 0,000 0,07136292 0,10992265 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,07136292 0,10985232 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07136292 0,10978208 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07136292 0,10971193 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07136292 0,10964188 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07136292 0,10957191 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07136292 0,10950203 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07136292 0,10943224 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07136292 0,10936253 ! regulation of cellular pH GO:0030641 22 13 0,000 0,07136292 0,10929292 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07136292 0,1092234 ! ribosome assembly GO:0042255 17 13 0,000 0,07136292 0,10915396 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07136292 0,10908461 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07136292 0,10901535 ! chromatin silencing GO:0006342 26 13 0,000 0,07136292 0,10894618 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07136292 0,10887709 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07136292 0,1088081 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07136292 0,10873919 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07136292 0,10867037 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07136292 0,10860163 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07136292 0,10853298 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07136292 0,10846442 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07136292 0,10839595 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07136292 0,10832756 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07136292 0,10825925 ! embryonic placenta development GO:0001892 23 13 0,000 0,07136292 0,10819104 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,07136292 0,10812291 ! insulin secretion GO:0030073 23 13 0,000 0,07136292 0,10805486 ! actin filament polymerization GO:0030041 24 13 0,000 0,07136292 0,1079869 ! acrosome reaction GO:0007340 18 13 0,000 0,07136292 0,10791903 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,07274239 0,10993605 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,07274239 0,10986703 ! protein oligomerization GO:0051259 139 78 1,000 0,07274239 0,10979811 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,07436233 0,1121729 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,07436233 0,11210262 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,07436233 0,11203242 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,07599382 0,11441873 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,07599382 0,11434717 ! protein import into nucleus GO:0006606 158 80 1,000 0,07599382 0,1142757 ! rRNA transcription GO:0009303 25 14 0,000 0,07663786 0,1151722 ! lactation GO:0007595 26 14 0,000 0,07663786 0,11510031 ! reproductive cellular process GO:0048610 20 14 0,000 0,07663786 0,11502851 ! tRNA modification GO:0006400 20 14 0,000 0,07663786 0,11495679 ! regulation of S phase GO:0033261 23 14 0,000 0,07663786 0,11488517 ! water transport GO:0006833 21 14 0,000 0,07663786 0,11481363 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07663786 0,11474219 ! non-recombinational repair GO:0000726 25 14 0,000 0,07663786 0,11467083 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,07663786 0,11459956 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07663786 0,11452838 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,07663786 0,11445729 ! RNA polyadenylation GO:0043631 30 14 0,000 0,07663786 0,11438629 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07663786 0,11431537 ! palate development GO:0060021 31 14 0,000 0,07663786 0,11424454 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07663786 0,11417381 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,07663786 0,11410315 ! arginine metabolic process GO:0006525 17 14 0,000 0,07663786 0,11403259 ! regulation of heart rate GO:0002027 24 14 0,000 0,07663786 0,11396211 ! organic alcohol transport GO:0015850 29 14 0,000 0,07663786 0,11389172 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,07663786 0,11382142 ! embryo implantation GO:0007566 30 14 0,000 0,07663786 0,1137512 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07663786 0,11368107 ! bone mineralization GO:0030282 17 14 0,000 0,07663786 0,11361103 ! stem cell development GO:0048864 43 14 0,000 0,07663786 0,11354107 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,07663786 0,1134712 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,07663786 0,11340141 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07663786 0,11333171 ! cerebellum development GO:0021549 21 14 0,000 0,07663786 0,1132621 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,07663786 0,11319257 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07663786 0,11312313 ! response to gamma radiation GO:0010332 28 14 0,000 0,07663786 0,11305377 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,07663786 0,11298449 ! cofactor transport GO:0051181 26 14 0,000 0,07663786 0,11291531 ! NADP metabolic process GO:0006739 24 14 0,000 0,07663786 0,1128462 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,07663786 0,11277718 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07663786 0,11270825 ! intestinal absorption GO:0050892 25 14 0,000 0,07663786 0,1126394 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,07663786 0,11257063 ! oxygen transport GO:0015671 21 14 0,000 0,07663786 0,11250195 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07663786 0,11243335 ! male genitalia development GO:0030539 24 14 0,000 0,07663786 0,11236484 ! regulation of axon extension GO:0030516 37 14 0,000 0,07663786 0,1122964 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,07663786 0,11222806 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,07663786 0,11215979 ! nuclear import GO:0051170 161 81 1,000 0,07763666 0,11355246 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,07929067 0,11590119 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,07929067 0,11583082 ! regulation of lyase activity GO:0051339 160 83 1,000 0,08095569 0,11819137 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,08188302 0,11947274 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08188302 0,11940033 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,08188302 0,11932801 ! superoxide anion generation GO:0042554 20 15 0,000 0,08188302 0,11925578 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,08188302 0,11918363 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,08188302 0,11911157 ! copper ion transport GO:0006825 20 15 0,000 0,08188302 0,1190396 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,08188302 0,11896772 ! sulfate transport GO:0008272 23 15 0,000 0,08188302 0,11889592 ! response to cAMP GO:0051591 22 15 0,000 0,08188302 0,11882421 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,08188302 0,11875259 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,08188302 0,11868105 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,08188302 0,1186096 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,08188302 0,11853823 ! response to hexose stimulus GO:0009746 22 15 0,000 0,08188302 0,11846695 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,08188302 0,11839576 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,08188302 0,11832465 ! pituitary gland development GO:0021983 29 15 0,000 0,08188302 0,11825363 ! vesicle coating GO:0006901 33 15 0,000 0,08188302 0,11818269 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,08188302 0,11811183 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,08188302 0,11804107 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,08188302 0,11797038 ! regulation of exocytosis GO:0017157 22 15 0,000 0,08188302 0,11789978 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,08188302 0,11782927 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,08188302 0,11775884 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,08188302 0,11768849 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,08188302 0,11761823 ! regulation of vasodilation GO:0042312 26 15 0,000 0,08188302 0,11754806 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,08188302 0,11747796 ! histone deacetylation GO:0016575 20 15 0,000 0,08188302 0,11740795 ! mRNA splice site selection GO:0006376 38 15 0,000 0,08188302 0,11733802 ! tissue regeneration GO:0042246 26 15 0,000 0,08188302 0,11726818 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,08188302 0,11719842 ! water homeostasis GO:0030104 27 15 0,000 0,08188302 0,11712874 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08188302 0,11705914 ! muscle maintenance GO:0046716 26 15 0,000 0,08188302 0,11698963 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,08188302 0,1169202 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,08188302 0,11685085 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,08188302 0,11678159 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08188302 0,11671241 ! heme biosynthetic process GO:0006783 29 15 0,000 0,08188302 0,1166433 ! cell killing GO:0001906 29 15 0,000 0,08188302 0,11657428 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,08188302 0,11650535 ! detection of bacterium GO:0016045 18 15 0,000 0,08188302 0,11643649 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,08188302 0,11636771 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,08188302 0,11629902 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,08188302 0,11623041 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,08188302 0,11616188 ! peptide hormone processing GO:0016486 23 15 0,000 0,08188302 0,11609342 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,08263152 0,11708565 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,08263152 0,11701674 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,084318 0,11933478 ! amine transport GO:0015837 155 86 1,000 0,08601496 0,1216649 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,08709855 0,12312521 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,08709855 0,12305292 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,08709855 0,1229807 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,08709855 0,12290857 ! bone remodeling GO:0046849 27 16 0,000 0,08709855 0,12283653 ! filopodium assembly GO:0046847 32 16 0,000 0,08709855 0,12276457 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,08709855 0,12269269 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,08709855 0,1226209 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,08709855 0,12254919 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,08709855 0,12247757 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,08709855 0,12240603 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,08709855 0,12233457 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,08709855 0,12226319 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,08709855 0,1221919 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,08709855 0,1221207 ! protein polyubiquitination GO:0000209 34 16 0,000 0,08709855 0,12204957 ! glutamate metabolic process GO:0006536 22 16 0,000 0,08709855 0,12197853 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,08709855 0,12190757 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,08709855 0,12183669 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,08709855 0,1217659 ! fructose metabolic process GO:0006000 25 16 0,000 0,08709855 0,12169519 ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08709855 0,12162456 ! intermediate filament-based process GO:0045103 32 16 0,000 0,08709855 0,12155401 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,08709855 0,12148354 ! negative regulation of immune response GO:0050777 35 16 0,000 0,08709855 0,12141316 ! axon cargo transport GO:0008088 43 16 0,000 0,08709855 0,12134286 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,08709855 0,12127264 ! DNA replication initiation GO:0006270 27 16 0,000 0,08709855 0,1212025 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,08709855 0,12113244 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,08709855 0,12106246 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,08709855 0,12099256 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,08709855 0,12092274 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,08709855 0,12085301 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,08709855 0,12078335 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,08709855 0,12071378 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08709855 0,12064428 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,08709855 0,12057486 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,08709855 0,12050553 ! defense response to virus GO:0051607 37 16 0,000 0,08709855 0,12043627 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,08772222 0,12122898 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 1,000 0,08772222 0,12115939 ! positive regulation of protein modification process GO:0031401 136 88 1,000 0,08943961 0,12346053 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,09116697 0,12577278 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,09228463 0,12724173 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,09228463 0,12716885 ! metencephalon development GO:0022037 30 17 0,000 0,09228463 0,12709606 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,09228463 0,12702335 ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,09228463 0,12695073 ! endothelial cell migration GO:0043542 28 17 0,000 0,09228463 0,12687818 ! inositol metabolic process GO:0006020 28 17 0,000 0,09228463 0,12680572 ! gene silencing by RNA GO:0031047 36 17 0,000 0,09228463 0,12673334 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,09228463 0,12666105 ! glial cell development GO:0021782 27 17 0,000 0,09228463 0,12658884 ! limbic system development GO:0021761 36 17 0,000 0,09228463 0,12651671 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,09228463 0,12644466 ! adult walking behavior GO:0007628 33 17 0,000 0,09228463 0,12637269 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,09228463 0,12630081 ! heart looping GO:0001947 30 17 0,000 0,09228463 0,12622901 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,09228463 0,12615728 ! myoblast differentiation GO:0045445 45 17 0,000 0,09228463 0,12608564 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,09228463 0,12601409 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,09228463 0,12594261 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,09228463 0,12587121 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,09228463 0,1257999 ! NAD metabolic process GO:0019674 29 17 0,000 0,09228463 0,12572866 ! membrane budding GO:0006900 37 17 0,000 0,09228463 0,12565751 ! DNA integration GO:0015074 29 17 0,000 0,09228463 0,12558644 ! regulation of protein binding GO:0043393 33 17 0,000 0,09228463 0,12551544 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,09228463 0,12544453 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,09228463 0,1253737 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,09228463 0,12530295 ! genitalia development GO:0048806 30 17 0,000 0,09228463 0,12523227 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,09228463 0,12516168 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,09228463 0,12509117 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,09228463 0,12502073 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,09228463 0,12495038 ! steroid catabolic process GO:0006706 31 17 0,000 0,09228463 0,1248801 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,09228463 0,1248099 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,09228463 0,12473979 ! gas transport GO:0015669 25 17 0,000 0,09228463 0,12466975 ! organic cation transport GO:0015695 31 17 0,000 0,09228463 0,12459979 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,09228463 0,1245299 ! microspike assembly GO:0030035 36 17 0,000 0,09228463 0,1244601 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,09228463 0,12439038 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,09228463 0,12432073 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,09290412 0,12508523 ! sex differentiation GO:0007548 145 90 1,000 0,09290412 0,12501527 ! cofactor biosynthetic process GO:0051188 139 91 1,000 0,0946509 0,12729462 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,09744142 0,13097433 ! neuron maturation GO:0042551 42 18 0,000 0,09744142 0,1309012 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,09744142 0,13082815 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,09744142 0,13075519 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,09744142 0,1306823 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,09744142 0,1306095 ! memory GO:0007613 31 18 0,000 0,09744142 0,13053678 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09744142 0,13046414 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,09744142 0,13039158 ! patterning of blood vessels GO:0001569 39 18 0,000 0,09744142 0,1303191 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,09744142 0,1302467 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,09744142 0,13017438 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,09744142 0,13010214 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09744142 0,13002998 ! response to retinoic acid GO:0032526 26 18 0,000 0,09744142 0,1299579 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,09744142 0,1298859 ! response to fungus GO:0009620 21 18 0,000 0,09744142 0,12981398 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,09744142 0,12974214 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,09744142 0,12967038 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,09744142 0,1295987 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,09744142 0,1295271 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,09744142 0,12945558 ! vitamin transport GO:0051180 27 18 0,000 0,09744142 0,12938413 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,09744142 0,12931277 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,09744142 0,12924148 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,09744142 0,12917028 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,09744142 0,12909915 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,09744142 0,1290281 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,09817271 0,12992494 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,09817271 0,12985351 ! forebrain development GO:0030900 188 95 1,000 0,1017311 0,13448627 ! protein secretion GO:0009306 39 19 0,000 0,10256908 0,13551961 ! positive regulation of translation GO:0045727 30 19 0,000 0,10256908 0,13544523 ! negative regulation of defense response GO:0031348 25 19 0,000 0,10256908 0,13537093 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,10256908 0,13529672 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,10256908 0,13522258 ! skin development GO:0043588 36 19 0,000 0,10256908 0,13514853 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,10256908 0,13507455 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,10256908 0,13500066 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,10256908 0,13492685 ! cerebral cortex development GO:0021987 36 19 0,000 0,10256908 0,13485312 ! pigmentation during development GO:0048066 41 19 0,000 0,10256908 0,13477947 ! response to vitamin A GO:0033189 27 19 0,000 0,10256908 0,1347059 ! heme metabolic process GO:0042168 36 19 0,000 0,10256908 0,13463241 ! neuromuscular junction development GO:0007528 34 19 0,000 0,10256908 0,134559 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,10256908 0,13448567 ! plasma membrane fusion GO:0045026 28 19 0,000 0,10256908 0,13441242 ! peptide cross-linking GO:0018149 37 19 0,000 0,10256908 0,13433925 ! protein export from nucleus GO:0006611 36 19 0,000 0,10256908 0,13426616 ! heart process GO:0003015 30 19 0,000 0,10256908 0,13419315 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,10256908 0,13412022 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,10256908 0,13404737 ! cellular pigmentation GO:0033059 36 19 0,000 0,10256908 0,1339746 ! G1 phase GO:0051318 40 19 0,000 0,10256908 0,1339019 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,10256908 0,13382929 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,10256908 0,13375675 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,10256908 0,1336843 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,10256908 0,13361192 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,10256908 0,13353962 ! cilium assembly GO:0042384 37 19 0,000 0,10256908 0,13346739 ! peptide hormone secretion GO:0030072 31 19 0,000 0,10256908 0,13339525 ! leukocyte differentiation GO:0002521 202 96 1,000 0,10352361 0,13456392 ! protein ubiquitination GO:0016567 217 97 1,000 0,1053248 0,13683124 ! hormone metabolic process GO:0042445 157 97 1,000 0,1053248 0,1367574 ! response to virus GO:0009615 160 98 1,000 0,1071345 0,13903215 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,10766778 0,13964889 ! positive regulation of ossification GO:0045778 47 20 0,000 0,10766778 0,13957364 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,10766778 0,13949848 ! cAMP metabolic process GO:0046058 36 20 0,000 0,10766778 0,1394234 ! response to vitamin GO:0033273 31 20 0,000 0,10766778 0,1393484 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,10766778 0,13927349 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,10766778 0,13919865 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,10766778 0,13912389 ! response to alkaloid GO:0043279 38 20 0,000 0,10766778 0,13904921 ! retinoid metabolic process GO:0001523 32 20 0,000 0,10766778 0,13897461 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,10766778 0,1389001 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,10766778 0,13882566 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,10766778 0,1387513 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,10766778 0,13867702 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,10766778 0,13860283 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,10766778 0,13852871 ! body fluid secretion GO:0007589 31 20 0,000 0,10766778 0,13845467 ! peptide secretion GO:0002790 35 20 0,000 0,10766778 0,13838071 ! stem cell differentiation GO:0048863 53 20 0,000 0,10766778 0,13830682 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,10766778 0,13823302 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,10766778 0,1381593 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,10766778 0,13808565 ! sensory perception of pain GO:0019233 30 20 0,000 0,10766778 0,13801208 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,10766778 0,1379386 ! diencephalon development GO:0021536 34 20 0,000 0,10766778 0,13786518 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,10766778 0,13779185 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,10766778 0,1377186 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,10766778 0,13764542 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,10766778 0,13757232 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,10766778 0,1374993 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,10766778 0,13742636 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,10766778 0,13735349 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,10766778 0,1372807 ! regulation of glucose import GO:0046324 29 20 0,000 0,10766778 0,13720799 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,10766778 0,13713535 ! actin filament-based movement GO:0030048 43 20 0,000 0,10766778 0,13706279 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,10766778 0,13699031 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,10766778 0,13691791 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,10766778 0,13684558 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,10895257 0,13840543 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,10895257 0,13833239 GO:0060538|skeletal muscle organ development, ! regulation of cell killing GO:0031341 42 21 0,000 0,11273768 0,14306269 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,11273768 0,14298728 ! hormone secretion GO:0046879 38 21 0,000 0,11273768 0,14291194 ! glycerol metabolic process GO:0006071 34 21 0,000 0,11273768 0,14283668 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,11273768 0,14276151 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,11273768 0,14268641 ! axis specification GO:0009798 38 21 0,000 0,11273768 0,14261139 ! ovarian follicle development GO:0001541 35 21 0,000 0,11273768 0,14253645 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,11273768 0,14246159 ! smooth muscle contraction GO:0006939 46 21 0,000 0,11273768 0,14238681 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,11273768 0,1423121 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,11273768 0,14223747 ! cell aging GO:0007569 44 21 0,000 0,11273768 0,14216293 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,11273768 0,14208846 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,11273768 0,14201406 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,11273768 0,14193975 ! cytolysis GO:0019835 24 21 0,000 0,11273768 0,14186551 ! vasodilation GO:0042311 39 21 0,000 0,11273768 0,14179136 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,11273768 0,14171727 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,11273768 0,14164327 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,11273768 0,14156934 ! oogenesis GO:0048477 36 21 0,000 0,11273768 0,1414955 ! collagen fibril organization GO:0030199 59 21 0,000 0,11273768 0,14142172 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,11273768 0,14134803 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,11273768 0,14127441 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,11273768 0,14120087 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,11273768 0,1411274 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,11273768 0,14105401 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,11273768 0,1409807 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,11273768 0,14090746 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,11273768 0,1408343 ! collagen catabolic process GO:0030574 28 21 0,000 0,11273768 0,14076122 ! sperm-egg recognition GO:0035036 21 21 0,000 0,11273768 0,14068821 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,11777895 0,14690313 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,11777895 0,14682702 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,11777895 0,14675098 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,11777895 0,14667502 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,11777895 0,14659914 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,11777895 0,14652334 ! regeneration GO:0031099 41 22 0,000 0,11777895 0,14644762 ! keratinization GO:0031424 28 22 0,000 0,11777895 0,14637197 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,11777895 0,14629641 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,11777895 0,14622092 ! sensory perception of taste GO:0050909 28 22 0,000 0,11777895 0,14614551 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,11777895 0,14607018 ! vacuolar transport GO:0007034 36 22 0,000 0,11777895 0,14599492 ! lysosome organization GO:0007040 41 22 0,000 0,11777895 0,14591974 ! central nervous system neuron development GO:0021954 46 22 0,000 0,11777895 0,14584464 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,11777895 0,14576962 ! fucose metabolic process GO:0006004 39 22 0,000 0,11777895 0,14569468 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,11777895 0,14561981 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,11777895 0,14554501 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,11777895 0,1454703 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,11777895 0,14539566 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,11777895 0,1453211 ! sarcomere organization GO:0045214 30 22 0,000 0,11777895 0,14524661 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,11777895 0,1451722 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,11777895 0,14509787 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,12279173 0,15119596 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,12279173 0,15111862 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,12279173 0,15104136 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,12279173 0,15096418 ! viral genome replication GO:0019079 41 23 0,000 0,12279173 0,15088708 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,12279173 0,15081006 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,12279173 0,15073312 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,12279173 0,15065625 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,12279173 0,15057946 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,12279173 0,15050275 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,12279173 0,15042612 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,12279173 0,15034957 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,12279173 0,1502731 ! peroxisome organization GO:0007031 37 23 0,000 0,12279173 0,1501967 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,12279173 0,15012038 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,12279173 0,15004414 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,12279173 0,14996797 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,12279173 0,14989189 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,12279173 0,14981588 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,12279173 0,14973994 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,12279173 0,14966409 ! fatty acid transport GO:0015908 44 23 0,000 0,12279173 0,14958831 ! platelet activation GO:0030168 37 23 0,000 0,12279173 0,1495126 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,12279173 0,14943698 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,12279173 0,14936143 ! hormone transport GO:0009914 40 23 0,000 0,12279173 0,14928596 ! cell-cell recognition GO:0009988 25 23 0,000 0,12279173 0,14921056 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,12279173 0,14913524 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,12279173 0,14905999 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,12279173 0,14898482 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,12279173 0,14890973 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,1277762 0,15487634 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,1277762 0,15479836 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,1277762 0,15472045 ! vesicle docking GO:0048278 47 24 0,000 0,1277762 0,15464263 ! vacuole organization GO:0007033 43 24 0,000 0,1277762 0,15456488 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,1277762 0,15448721 ! digestive system process GO:0022600 39 24 0,000 0,1277762 0,15440961 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,1277762 0,1543321 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,1277762 0,15425466 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,1277762 0,1541773 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,1277762 0,15410002 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,1277762 0,15402282 ! pallium development GO:0021543 49 24 0,000 0,1277762 0,15394569 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,1277762 0,15386864 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,1277762 0,15379167 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,1277762 0,15371477 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,1277762 0,15363795 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,1277762 0,15356121 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,1277762 0,15348454 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,1277762 0,15340795 ! regulation of amine transport GO:0051952 40 24 0,000 0,1277762 0,15333144 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,13273251 0,15919961 ! myelination GO:0042552 45 25 0,000 0,13273251 0,15912029 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,13273251 0,15904105 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,13273251 0,15896188 ! phototransduction GO:0007602 33 25 0,000 0,13273251 0,1588828 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,13273251 0,15880379 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,13273251 0,15872486 ! sperm motility GO:0030317 31 25 0,000 0,13273251 0,15864601 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,13273251 0,15856724 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,13273251 0,15848855 ! response to starvation GO:0042594 42 25 0,000 0,13273251 0,15840993 ! osteoblast differentiation GO:0001649 60 25 0,000 0,13273251 0,1583314 ! neural crest cell development GO:0014032 54 25 0,000 0,13273251 0,15825294 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,13273251 0,15817455 ! negative regulation of cell development GO:0010721 73 25 0,000 0,13273251 0,15809625 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,13273251 0,15801802 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,13273251 0,15793987 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,13273251 0,1578618 ! immunoglobulin production GO:0002377 55 25 0,000 0,13273251 0,15778381 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,13273251 0,15770589 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,13273251 0,15762805 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,13273251 0,15755028 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,13273251 0,1574726 ! telomere organization GO:0032200 43 25 0,000 0,13273251 0,15739498 GO:0000723|telomere maintenance, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,13766082 0,16315859 ! embryonic pattern specification GO:0009880 44 26 0,000 0,13766082 0,16307826 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,13766082 0,162998 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,13766082 0,16291783 ! initiation of viral infection GO:0019059 57 26 0,000 0,13766082 0,16283773 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,13766082 0,16275771 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,13766082 0,16267777 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,13766082 0,16259791 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,13766082 0,16251813 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,13766082 0,16243842 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,13766082 0,16235879 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,13766082 0,16227925 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,13766082 0,16219978 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,13766082 0,16212038 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,13766082 0,16204107 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,13766082 0,16196183 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,13766082 0,16188267 ! leukocyte proliferation GO:0070661 52 26 0,000 0,13766082 0,16180359 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,13766082 0,16172458 ! iron ion transport GO:0006826 59 27 0,000 0,14256129 0,16739994 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,14256129 0,16731828 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,14256129 0,1672367 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,14256129 0,1671552 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,14256129 0,16707378 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,14256129 0,16699244 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,14256129 0,16691118 ! autophagy GO:0006914 41 27 0,000 0,14256129 0,16682999 ! male gonad development GO:0008584 44 27 0,000 0,14256129 0,16674889 ! response to toxin GO:0009636 47 27 0,000 0,14256129 0,16666787 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,14256129 0,16658692 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,14256129 0,16650605 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,14256129 0,16642526 ! glutathione metabolic process GO:0006749 39 27 0,000 0,14256129 0,16634455 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,14256129 0,16626392 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,14256129 0,16618337 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,14256129 0,16610289 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,14743407 0,17169718 ! circadian rhythm GO:0007623 50 28 0,000 0,14743407 0,17161412 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,14743407 0,17153113 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,14743407 0,17144823 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,14743407 0,1713654 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,14743407 0,17128266 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,14743407 0,17119999 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,14743407 0,17111741 ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,14743407 0,1710349 ! translational initiation GO:0006413 65 29 0,000 0,15227933 0,17657063 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,15227933 0,17648558 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,15227933 0,17640061 ! regulation of pH GO:0006885 43 29 0,000 0,15227933 0,17631572 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,15227933 0,17623091 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,15227933 0,17614618 ! catechol metabolic process GO:0009712 54 29 0,000 0,15227933 0,17606154 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,15227933 0,17597697 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,15227933 0,17589249 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,15227933 0,17580809 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,15227933 0,17572377 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,15227933 0,17563953 ! cell fate determination GO:0001709 60 29 0,000 0,15227933 0,17555537 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,15227933 0,17547129 ! detection of light stimulus GO:0009583 38 29 0,000 0,15227933 0,17538729 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,15227933 0,17530338 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,15227933 0,17521954 ! phenol metabolic process GO:0018958 55 30 0,000 0,1570972 0,1806768 ! zinc ion transport GO:0006829 45 30 0,000 0,1570972 0,18059048 ! membrane docking GO:0022406 61 30 0,000 0,1570972 0,18050423 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,1570972 0,18041807 ! regulation of innate immune response GO:0045088 51 30 0,000 0,1570972 0,180332 ! acute-phase response GO:0006953 49 30 0,000 0,1570972 0,180246 ! myofibril assembly GO:0030239 47 30 0,000 0,1570972 0,18016009 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,1570972 0,18007426 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,1570972 0,17998851 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,1570972 0,17990284 ! phospholipid transport GO:0015914 51 30 0,000 0,1570972 0,17981725 ! ensheathment of neurons GO:0007272 57 30 0,000 0,1570972 0,17973175 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,1570972 0,17964632 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,1570972 0,17956098 ! response to heat GO:0009408 50 30 0,000 0,1570972 0,17947572 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,16188785 0,18486102 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,16188785 0,18477333 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,16188785 0,18468572 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,16188785 0,18459819 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,16188785 0,18451074 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,16188785 0,18442338 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,16188785 0,1843361 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,16188785 0,1842489 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,16188785 0,18416179 ! ovulation cycle process GO:0022602 49 31 0,000 0,16188785 0,18407475 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,16188785 0,1839878 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,16188785 0,18390093 ! peptide transport GO:0015833 55 31 0,000 0,16188785 0,18381415 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,16188785 0,18372744 ! iron ion homeostasis GO:0055072 54 31 0,000 0,16188785 0,18364082 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,16188785 0,18355428 ! mesoderm formation GO:0001707 69 31 0,000 0,16188785 0,18346782 ! natural killer cell activation GO:0030101 45 31 0,000 0,16188785 0,18338144 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,16188785 0,18329514 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,16188785 0,18320893 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,16665144 0,18851122 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,16665144 0,18842263 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,16665144 0,18833413 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,16665144 0,18824571 ! cholesterol transport GO:0030301 56 32 0,000 0,16665144 0,18815737 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,16665144 0,18806912 ! spliceosome assembly GO:0000245 67 32 0,000 0,16665144 0,18798095 ! spindle organization GO:0007051 46 32 0,000 0,16665144 0,18789286 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,16665144 0,18780485 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,16665144 0,18771693 ! response to ionizing radiation GO:0010212 65 32 0,000 0,16665144 0,18762909 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,16665144 0,18754133 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,16665144 0,18745365 ! muscle cell development GO:0055001 49 32 0,000 0,16665144 0,18736606 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,16665144 0,18727854 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,16665144 0,18719111 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,16665144 0,18710376 ! ovulation cycle GO:0042698 51 32 0,000 0,16665144 0,18701649 ! peripheral nervous system development GO:0007422 64 32 0,000 0,16665144 0,1869293 ! BMP signaling pathway GO:0030509 64 32 0,000 0,16665144 0,1868422 ! hindbrain development GO:0030902 61 32 0,000 0,16665144 0,18675517 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,16665144 0,18666823 ! gene silencing GO:0016458 65 32 0,000 0,16665144 0,18658137 ! post-embryonic development GO:0009791 69 33 0,000 0,1713881 0,19179525 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,1713881 0,19170608 ! protein targeting to membrane GO:0006612 68 33 0,000 0,1713881 0,191617 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,1713881 0,191528 ! ceramide metabolic process GO:0006672 64 33 0,000 0,1713881 0,19143908 ! formation of primary germ layer GO:0001704 72 33 0,000 0,1713881 0,19135025 ! sterol transport GO:0015918 57 33 0,000 0,1713881 0,19126149 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,1713881 0,19117282 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,1713881 0,19108423 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,176098 0,19624446 ! glial cell differentiation GO:0010001 63 34 0,000 0,176098 0,19615361 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,176098 0,19606284 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,176098 0,19597215 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,176098 0,19588155 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,176098 0,19579103 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,176098 0,1957006 ! mismatch repair GO:0006298 46 34 0,000 0,176098 0,19561025 ! spermatid development GO:0007286 63 34 0,000 0,176098 0,19551998 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,176098 0,1954298 ! negative regulation of secretion GO:0051048 63 35 0,000 0,18078129 0,20053471 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,18078129 0,20044229 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,18078129 0,20034997 ! female gonad development GO:0008585 58 35 0,000 0,18078129 0,20025773 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,18078129 0,20016557 GO:0006639|acylglycerol metabolic process, ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,18078129 0,2000735 ! cytokine production GO:0001816 59 35 0,000 0,18078129 0,19998151 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,18078129 0,1998896 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,18543811 0,20494446 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,18543811 0,20485036 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,18543811 0,20475635 ! positive regulation of cell development GO:0010720 80 36 0,000 0,18543811 0,20466242 ! regulation of proteolysis GO:0030162 72 36 0,000 0,18543811 0,20456858 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,18543811 0,20447483 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,18543811 0,20438117 ! aerobic respiration GO:0009060 55 36 0,000 0,18543811 0,20428758 ! RNA export from nucleus GO:0006405 56 37 0,000 0,19006861 0,20929294 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,19006861 0,20919719 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,19006861 0,20910154 ! actomyosin structure organization GO:0031032 62 37 0,000 0,19006861 0,20900597 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,19006861 0,20891049 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,19006861 0,2088151 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,19006861 0,20871979 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,19006861 0,20862457 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,19006861 0,20852944 ! pigment metabolic process GO:0042440 80 37 0,000 0,19006861 0,2084344 ! spermatid differentiation GO:0048515 66 37 0,000 0,19006861 0,20833944 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,19467294 0,2132892 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,19467294 0,21319212 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,19467294 0,21309513 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,19467294 0,21299822 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,19467294 0,2129014 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,19467294 0,21280467 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,19467294 0,21270803 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,19467294 0,21261148 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,19467294 0,21251501 ! glucan metabolic process GO:0044042 62 38 0,000 0,19467294 0,21241863 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,19925125 0,21731573 ! ear morphogenesis GO:0042471 60 39 0,000 0,19925125 0,21721726 ! organic ether metabolic process GO:0018904 55 39 0,000 0,19925125 0,21711888 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,19925125 0,2170206 ! ion transmembrane transport GO:0034220 66 39 0,000 0,19925125 0,2169224 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,19925125 0,21682429 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,19925125 0,21672626 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,19925125 0,21662833 ! RNA modification GO:0009451 57 39 0,000 0,19925125 0,21653049 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,19925125 0,21643273 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,20380368 0,22127782 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,20380368 0,22117801 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,20380368 0,22107829 ! feeding behavior GO:0007631 59 40 0,000 0,20380368 0,22097866 ! mesenchymal cell development GO:0014031 87 40 0,000 0,20380368 0,22087912 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! cytokinesis GO:0000910 72 40 0,000 0,20380368 0,22077967 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,20833038 0,22558186 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,20833038 0,22548038 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,20833038 0,225379 ! gliogenesis GO:0042063 88 41 0,000 0,20833038 0,2252777 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,20833038 0,2251765 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,20833038 0,22507539 ! female gamete generation GO:0007292 61 41 0,000 0,20833038 0,22497437 ! polyol metabolic process GO:0019751 66 41 0,000 0,20833038 0,22487344 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,21283149 0,22962895 ! regulation of tube size GO:0035150 71 42 0,000 0,21283149 0,22952603 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,21283149 0,22942319 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,21283149 0,22932045 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,21283149 0,2292178 ! regulation of protein secretion GO:0050708 71 42 0,000 0,21283149 0,22911524 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,21283149 0,22901278 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,21730716 0,2337242 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,21730716 0,23361977 ! glucose transport GO:0015758 65 43 0,000 0,21730716 0,23351542 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,21730716 0,23341118 ! striated muscle contraction GO:0006941 77 43 0,000 0,21730716 0,23330702 ! phagocytosis GO:0006909 90 43 0,000 0,21730716 0,23320296 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,22175753 0,23787277 ! hexose transport GO:0008645 67 44 0,000 0,22175753 0,23776677 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,22175753 0,23766086 ! double-strand break repair GO:0006302 81 44 0,000 0,22175753 0,23755504 ! B cell differentiation GO:0030183 107 44 0,000 0,22175753 0,23744932 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,22175753 0,2373437 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,22175753 0,23723816 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,22618275 0,24186475 ! glycolysis GO:0006096 65 45 0,000 0,22618275 0,2417573 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,22618275 0,24164995 ! leukocyte migration GO:0050900 68 45 0,000 0,22618275 0,2415427 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,22618275 0,24143553 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,22618275 0,24132847 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,22618275 0,2412215 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,22618275 0,24111462 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,22618275 0,24100784 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,23058295 0,24558768 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,23058295 0,24547901 ! pigmentation GO:0043473 100 46 0,000 0,23058295 0,24537044 ! positive regulation of defense response GO:0031349 76 47 0,000 0,23495827 0,24991582 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,23495827 0,24980539 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,23495827 0,24969505 ! protein homooligomerization GO:0051260 76 47 0,000 0,23495827 0,24958481 ! mitochondrial transport GO:0006839 82 48 0,000 0,23930886 0,25409404 ! Notch signaling pathway GO:0007219 96 48 0,000 0,23930886 0,25398196 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,23930886 0,25386998 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,23930886 0,25375809 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,23930886 0,2536463 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,24363484 0,25811776 ! regulation of action potential GO:0001508 95 49 0,000 0,24363484 0,25800415 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,24363484 0,25789065 ! regulation of ion transport GO:0043269 77 49 0,000 0,24363484 0,25777724 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,24363484 0,25766393 ! peptide metabolic process GO:0006518 76 49 0,000 0,24363484 0,25755072 ! response to temperature stimulus GO:0009266 76 49 0,000 0,24363484 0,25743761 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,24363484 0,2573246 ! endocrine system development GO:0035270 104 49 0,000 0,24363484 0,25721169 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,24363484 0,25709888 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,24363484 0,25698616 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,24363484 0,25687355 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,24363484 0,25676103 ! regulation of ossification GO:0030278 117 50 0,000 0,24793638 0,26117991 ! inner ear development GO:0048839 79 50 0,000 0,24793638 0,26106561 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,24793638 0,26095141 ! viral infectious cycle GO:0019058 99 51 0,000 0,25221359 0,26533707 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,25221359 0,26522111 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,25221359 0,26510524 ! excretion GO:0007588 83 51 0,000 0,25221359 0,26498947 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,25221359 0,26487381 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,25221359 0,26475824 ! vesicle organization GO:0016050 107 51 0,000 0,25221359 0,26464278 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,25646661 0,26898809 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,25646661 0,26887088 ! membrane fusion GO:0006944 110 52 0,000 0,25646661 0,26875378 ! amino acid activation GO:0043038 92 52 0,000 0,25646661 0,26863677 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,26069559 0,2729476 ! RNA catabolic process GO:0006401 93 53 0,000 0,26069559 0,27282888 ! regulation of translational initiation GO:0006446 82 53 0,000 0,26069559 0,27271026 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,26069559 0,27259174 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,26069559 0,27247332 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,26069559 0,27235501 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,26490065 0,27662803 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,26490065 0,27650801 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,26490065 0,27638811 ! chloride transport GO:0006821 90 55 0,000 0,26908194 0,28062902 ! glucose catabolic process GO:0006007 82 55 0,000 0,26908194 0,28050743 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,26908194 0,28038595 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,26908194 0,28026457 ! gastrulation GO:0007369 112 55 0,000 0,26908194 0,28014329 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,26908194 0,28002212 ! nuclear export GO:0051168 97 55 0,000 0,26908194 0,27990106 ! regulation of actin filament length GO:0030832 105 56 0,000 0,27323958 0,28410304 ! sensory perception of smell GO:0007608 80 56 0,000 0,27323958 0,28398032 ! skeletal muscle fiber development GO:0048741 111 56 0,000 0,27323958 0,2838577 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,27323958 0,28373519 ! proton transport GO:0015992 94 56 0,000 0,27323958 0,28361278 ! muscle fiber development GO:0048747 112 57 0,000 0,27737371 0,28777971 ! hydrogen transport GO:0006818 97 58 0,000 0,28148446 0,29191879 ! regulation of endocytosis GO:0030100 91 58 0,000 0,28148446 0,29179302 ! positive regulation of secretion GO:0051047 95 59 0,000 0,28557196 0,29590273 ! regulation of cellular component size GO:0032535 109 59 0,000 0,28557196 0,29577535 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,28557196 0,29564808 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,28557196 0,29552092 ! regulation of heart contraction GO:0008016 110 60 0,000 0,28963634 0,29959804 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,28963634 0,29946929 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,29367773 0,30351745 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,29367773 0,30338713 ! tRNA processing GO:0008033 89 61 0,000 0,29367773 0,30325692 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,29367773 0,30312682 ! ear development GO:0043583 103 62 0,000 0,29769627 0,30714289 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,29769627 0,30701124 ! detection of external stimulus GO:0009581 91 63 0,000 0,30169207 0,31099877 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,30566528 0,3149596 ! cell redox homeostasis GO:0045454 102 64 0,000 0,30566528 0,31482477 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,30566528 0,31469005 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,30566528 0,31455546 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,30566528 0,31442097 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,30961601 0,31834877 ! germ cell development GO:0007281 118 65 0,000 0,30961601 0,31821278 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,31354439 0,32211264 ! extracellular matrix organization GO:0030198 133 66 0,000 0,31354439 0,32197516 ! secondary metabolic process GO:0019748 116 66 0,000 0,31354439 0,3218378 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,31745054 0,32570832 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,31745054 0,32556948 ! hexose catabolic process GO:0019320 104 67 0,000 0,31745054 0,32543076 ! activation of immune response GO:0002253 105 67 0,000 0,31745054 0,32529217 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,3213346 0,32913199 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,3213346 0,32899194 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,32519669 0,33280443 ! antigen processing and presentation GO:0019882 104 69 0,000 0,32519669 0,33266294 ! humoral immune response GO:0006959 109 71 0,000 0,33285543 0,34035281 ! B cell activation GO:0042113 160 71 0,000 0,33285543 0,34020822 ! regulation of immune effector process GO:0002697 137 71 0,000 0,33285543 0,34006376 ! acute inflammatory response GO:0002526 113 72 0,000 0,33665233 0,3437969 ! carbohydrate transport GO:0008643 110 72 0,000 0,33665233 0,34365104 ! regulation of blood pressure GO:0008217 125 73 0,000 0,34042775 0,34735757 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,34042775 0,34721033 ! fertilization GO:0009566 90 73 0,000 0,34042775 0,3470632 ! transition metal ion transport GO:0000041 126 74 0,000 0,3441818 0,35074181 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,3441818 0,35059332 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,3441818 0,35044495 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,34791462 0,35409584 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,34791462 0,35394612 ! rhythmic process GO:0048511 128 75 0,000 0,34791462 0,35379652 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,35162631 0,3574199 ! defense response to bacterium GO:0042742 89 76 0,000 0,35162631 0,35726896 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,35162631 0,35711815 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,35162631 0,35696747 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,35531699 0,36056208 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,35531699 0,36041007 ! blood coagulation GO:0007596 146 78 0,000 0,35898679 0,36397902 GO:0050817|coagulation, ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,36263583 0,36752392 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,36263583 0,36736918 ! muscle cell differentiation GO:0042692 159 80 0,000 0,3662642 0,37088875 ! inorganic anion transport GO:0015698 138 80 0,000 0,3662642 0,37073272 ! digestion GO:0007586 112 81 0,000 0,36987205 0,37422714 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,36987205 0,37406984 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,37345947 0,37753928 ! response to nutrient GO:0007584 125 82 0,000 0,37345947 0,37738072 ! hemostasis GO:0007599 158 84 0,000 0,38057352 0,38440802 ! nucleosome assembly GO:0006334 122 85 0,000 0,38410037 0,38780759 ! amine biosynthetic process GO:0009309 138 86 0,000 0,38760726 0,39118417 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,38760726 0,39102015 ! chromatin assembly GO:0031497 124 86 0,000 0,38760726 0,39085627 ! alcohol catabolic process GO:0046164 130 86 0,000 0,38760726 0,39069253 ! cellular respiration GO:0045333 135 88 0,000 0,39456159 0,39753567 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,39456159 0,39736927 ! cellular defense response GO:0006968 114 89 0,000 0,39800926 0,40067375 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,4014374 0,40395583 ! sterol metabolic process GO:0016125 152 91 0,000 0,40484614 0,40721564 ! regulation of defense response GO:0031347 149 92 0,000 0,40823558 0,41045333 ! nucleosome organization GO:0034728 138 92 0,000 0,40823558 0,41028188 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,40823558 0,41011057 ! vitamin metabolic process GO:0006766 139 92 0,000 0,40823558 0,4099394 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,414957 0,41651503 ! female pregnancy GO:0007565 164 94 0,000 0,414957 0,41634134 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,41828919 0,41950971 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,42160251 0,42265652 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,42160251 0,42248048 ! positive regulation of immune response GO:0050778 156 96 0,000 0,42160251 0,4223046 ! detection of stimulus GO:0051606 151 96 0,000 0,42160251 0,42212885 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,42489707 0,42525056 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,42817297 0,42835101 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,43143032 0,43143032