pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6495-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of DNA replication GO:0006275 32 31 4,000 8,154E-08 1,503E-04 ! positive regulation of protein kinase activity GO:0045860 89 86 5,000 6,028E-07 5,554E-04 ! positive regulation of transferase activity GO:0051347 91 88 5,000 6,913E-07 4,247E-04 GO:0033674|positive regulation of kinase activity, ! positive regulation of MAP kinase activity GO:0043406 50 49 4,000 8,74E-07 4,027E-04 ! regulation of DNA metabolic process GO:0051052 51 50 4,000 9,687E-07 3,571E-04 ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 3,086E-06 9,479E-04 ! regulation of MAP kinase activity GO:0043405 67 66 4,000 3,922E-06 1,033E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 7,75E-06 1,785E-03 ! integrin-mediated signaling pathway GO:0007229 36 36 3,000 8,698E-06 1,781E-03 ! positive regulation of DNA replication GO:0045740 14 13 2,000 1,337E-05 2,463E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 1,337E-05 2,239E-03 ! protein tetramerization GO:0051262 13 13 2,000 1,337E-05 2,053E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 1,697E-05 2,406E-03 ! insulin receptor signaling pathway GO:0008286 17 15 2,000 2,116E-05 2,785E-03 ! regulation of DNA binding GO:0051101 47 45 3,000 2,15E-05 2,641E-03 ! cellular response to hormone stimulus GO:0032870 48 46 3,000 2,349E-05 2,705E-03 ! cell junction assembly GO:0034329 18 17 2,000 3,146E-05 3,411E-03 ! DNA damage checkpoint GO:0000077 19 19 2,000 4,461E-05 4,568E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 2,000 4,461E-05 4,327E-03 ! peptidyl-tyrosine modification GO:0018212 21 20 2,000 5,235E-05 4,824E-03 ! regulation of binding GO:0051098 60 57 3,000 5,527E-05 4,85E-03 ! DNA integrity checkpoint GO:0031570 21 21 2,000 6,092E-05 5,104E-03 ! cellular response to insulin stimulus GO:0032869 23 21 2,000 6,092E-05 4,882E-03 ! peptidyl-amino acid modification GO:0018193 61 59 3,000 6,335E-05 4,865E-03 ! positive regulation of DNA metabolic process GO:0051054 23 22 2,000 7,036E-05 5,187E-03 ! cell junction organization GO:0034330 23 22 2,000 7,036E-05 4,988E-03 ! glucose homeostasis GO:0042593 24 24 2,000 9,202E-05 6,281E-03 GO:0033500|carbohydrate homeostasis, ! regulation of gene-specific transcription GO:0032583 25 25 2,000 1,043E-04 6,865E-03 ! regulation of intracellular protein transport GO:0033157 25 25 2,000 1,043E-04 6,629E-03 ! positive regulation of DNA binding GO:0043388 26 25 2,000 1,043E-04 6,408E-03 ! positive regulation of binding GO:0051099 27 26 2,000 1,176E-04 6,992E-03 ! response to insulin stimulus GO:0032868 28 26 2,000 1,176E-04 6,774E-03 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 2,000 1,32E-04 7,371E-03 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 1,364E-04 7,393E-03 ! memory GO:0007613 5 5 1,000 1,364E-04 7,182E-03 ! dopamine receptor signaling pathway GO:0007212 5 5 1,000 1,364E-04 6,982E-03 ! endocrine pancreas development GO:0031018 5 5 1,000 1,364E-04 6,793E-03 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 1,364E-04 6,615E-03 ! receptor clustering GO:0043113 5 5 1,000 1,364E-04 6,445E-03 ! actin cytoskeleton reorganization GO:0031532 5 5 1,000 1,364E-04 6,284E-03 ! wound healing, spreading of epidermal cells GO:0035313 5 5 1,000 1,364E-04 6,131E-03 ! protein heterooligomerization GO:0051291 5 5 1,000 1,364E-04 5,985E-03 ! T cell lineage commitment GO:0002360 5 5 1,000 1,364E-04 5,846E-03 ! peptidyl-lysine modification GO:0018205 5 5 1,000 1,364E-04 5,713E-03 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 1,364E-04 5,586E-03 ! leukocyte mediated cytotoxicity GO:0001909 5 5 1,000 1,364E-04 5,464E-03 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 1,641E-04 6,433E-03 ! response to UV GO:0009411 29 29 2,000 1,641E-04 6,299E-03 ! cell morphogenesis involved in differentiation GO:0000904 82 77 3,000 1,799E-04 6,766E-03 ! positive regulation of protein kinase cascade GO:0010740 79 78 3,000 1,891E-04 6,971E-03 ! regulation of intracellular transport GO:0032386 31 31 2,000 2,008E-04 7,256E-03 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 1,000 2,041E-04 7,234E-03 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 2,041E-04 7,097E-03 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 2,041E-04 6,966E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 2,041E-04 6,839E-03 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 1,000 2,041E-04 6,717E-03 ! ER overload response GO:0006983 6 6 1,000 2,041E-04 6,599E-03 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 2,041E-04 6,486E-03 GO:0070667|negative regulation of mast cell proliferation, ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 2,041E-04 6,376E-03 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 2,041E-04 6,269E-03 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 2,041E-04 6,167E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 2,041E-04 6,067E-03 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 2,041E-04 5,971E-03 ! localization within membrane GO:0051668 6 6 1,000 2,041E-04 5,877E-03 ! MAPKKK cascade GO:0000165 82 81 3,000 2,189E-04 6,206E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 2,000 2,21E-04 6,172E-03 ! response to peptide hormone stimulus GO:0043434 36 34 2,000 2,653E-04 7,298E-03 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 1,000 2,851E-04 7,726E-03 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 2,851E-04 7,614E-03 ! positive regulation of survival gene product expression GO:0045885 7 7 1,000 2,851E-04 7,506E-03 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 2,851E-04 7,4E-03 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! response to X-ray GO:0010165 7 7 1,000 2,851E-04 7,297E-03 ! regulation of intracellular pH GO:0051453 7 7 1,000 2,851E-04 7,197E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 2,851E-04 7,1E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! axon cargo transport GO:0008088 7 7 1,000 2,851E-04 7,005E-03 ! induction of an organ GO:0001759 7 7 1,000 2,851E-04 6,913E-03 ! response to gamma radiation GO:0010332 8 7 1,000 2,851E-04 6,823E-03 ! cell killing GO:0001906 7 7 1,000 2,851E-04 6,736E-03 ! negative regulation of T cell activation GO:0050868 7 7 1,000 2,851E-04 6,651E-03 ! heart development GO:0007507 90 87 3,000 2,884E-04 6,643E-03 ! positive regulation of phosphorylation GO:0042327 35 35 2,000 2,895E-04 6,586E-03 ! positive regulation of cell migration GO:0030335 36 36 2,000 3,15E-04 7,079E-03 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 2,000 3,15E-04 6,994E-03 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of transcription factor activity GO:0051090 38 37 2,000 3,419E-04 7,502E-03 GO:0090046|regulation of transcription regulator activity, ! lung development GO:0030324 38 37 2,000 3,419E-04 7,414E-03 ! DNA damage response, signal transduction GO:0042770 37 37 2,000 3,419E-04 7,327E-03 ! pancreas development GO:0031016 8 8 1,000 3,792E-04 8,033E-03 ! cell-cell junction assembly GO:0007043 8 8 1,000 3,792E-04 7,942E-03 ! sex determination GO:0007530 8 8 1,000 3,792E-04 7,853E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 3,792E-04 7,766E-03 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 3,792E-04 7,68E-03 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 3,792E-04 7,597E-03 ! developmental induction GO:0031128 8 8 1,000 3,792E-04 7,515E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 3,792E-04 7,435E-03 ! activation of MAPK activity GO:0000187 39 39 2,000 4,001E-04 7,763E-03 ! respiratory tube development GO:0030323 40 39 2,000 4,001E-04 7,682E-03 ! cytokine-mediated signaling pathway GO:0019221 39 39 2,000 4,001E-04 7,603E-03 ! respiratory system development GO:0060541 40 39 2,000 4,001E-04 7,525E-03 ! protein oligomerization GO:0051259 39 39 2,000 4,001E-04 7,449E-03 ! positive regulation of cell motion GO:0051272 39 39 2,000 4,001E-04 7,375E-03 ! cell cycle checkpoint GO:0000075 42 41 2,000 4,644E-04 8,474E-03 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 4,864E-04 8,789E-03 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 4,864E-04 8,704E-03 ! prostaglandin metabolic process GO:0006693 9 9 1,000 4,864E-04 8,62E-03 GO:0006692|prostanoid metabolic process, ! regulation of cellular pH GO:0030641 9 9 1,000 4,864E-04 8,538E-03 ! histone acetylation GO:0016573 9 9 1,000 4,864E-04 8,458E-03 ! response to hormone stimulus GO:0009725 102 100 3,000 4,913E-04 8,463E-03 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 1,000 6,066E-04 0,01035207 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 6,066E-04 0,0102571 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 6,066E-04 0,01016385 ! regulation of survival gene product expression GO:0045884 10 10 1,000 6,066E-04 0,01007229 ! cell-substrate junction assembly GO:0007044 11 10 1,000 6,066E-04 9,982E-03 ! neuromuscular junction development GO:0007528 10 10 1,000 6,066E-04 9,894E-03 ! intermediate filament cytoskeleton organization GO:0045104 10 10 1,000 6,066E-04 9,807E-03 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 6,066E-04 9,722E-03 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 6,066E-04 9,638E-03 ! protein stabilization GO:0050821 10 10 1,000 6,066E-04 9,556E-03 ! regulation of catabolic process GO:0009894 48 47 2,000 6,959E-04 0,01086856 ! G1 phase of mitotic cell cycle GO:0000080 12 11 1,000 7,397E-04 0,0114563 ! positive regulation of hormone secretion GO:0046887 11 11 1,000 7,397E-04 0,01136083 ! signal complex assembly GO:0007172 11 11 1,000 7,397E-04 0,01126694 ! microtubule-based transport GO:0010970 11 11 1,000 7,397E-04 0,01117458 ! protein amino acid acetylation GO:0006473 11 11 1,000 7,397E-04 0,01108373 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 7,397E-04 0,01099435 GO:0032388|positive regulation of intracellular transport, ! activation of MAPKK activity GO:0000186 12 11 1,000 7,397E-04 0,01090639 ! cellular response to starvation GO:0009267 11 11 1,000 7,397E-04 0,01081984 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 7,397E-04 0,01073464 ! G1/S transition checkpoint GO:0031575 12 11 1,000 7,397E-04 0,01065078 ! intermediate filament-based process GO:0045103 11 11 1,000 7,397E-04 0,01056821 ! interaction with host GO:0051701 11 11 1,000 7,397E-04 0,01048692 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 7,397E-04 0,01040686 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 7,397E-04 0,01032802 GO:0006109|regulation of carbohydrate metabolic process, ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 7,397E-04 0,01025037 ! cell cycle arrest GO:0007050 49 49 2,000 7,867E-04 0,01082032 ! skeletal muscle tissue development GO:0007519 50 49 2,000 7,867E-04 0,01074017 GO:0060538|skeletal muscle organ development, ! negative regulation of transport GO:0051051 51 50 2,000 8,348E-04 0,01131332 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 2,000 8,348E-04 0,01123074 ! interphase of mitotic cell cycle GO:0051329 52 51 2,000 8,848E-04 0,01181656 GO:0051325|interphase, ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 1,000 8,856E-04 0,01174216 ! heterophilic cell adhesion GO:0007157 12 12 1,000 8,856E-04 0,01165828 ! regulation of insulin secretion GO:0050796 12 12 1,000 8,856E-04 0,0115756 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 1,000 8,856E-04 0,01149408 ! somitogenesis GO:0001756 13 12 1,000 8,856E-04 0,0114137 ! G1 phase GO:0051318 13 12 1,000 8,856E-04 0,01133444 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 1,000 8,856E-04 0,01125627 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 8,856E-04 0,01117918 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 2,000 9,366E-04 0,01174281 ! cell fate commitment GO:0045165 52 52 2,000 9,366E-04 0,01166347 ! response to light stimulus GO:0009416 53 52 2,000 9,366E-04 0,01158519 ! regulation of protein transport GO:0051223 53 53 2,000 9,903E-04 0,01216792 GO:0070201|regulation of establishment of protein localization, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 1,000 1,044E-03 0,01274462 ! negative regulation of hormone secretion GO:0046888 13 13 1,000 1,044E-03 0,01266077 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 1,000 1,044E-03 0,01257802 ! vasculogenesis GO:0001570 13 13 1,000 1,044E-03 0,01249634 ! mitochondrial membrane organization GO:0007006 13 13 1,000 1,044E-03 0,01241572 ! negative regulation of DNA replication GO:0008156 13 13 1,000 1,044E-03 0,01233614 ! receptor metabolic process GO:0043112 14 13 1,000 1,044E-03 0,01225756 ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 1,044E-03 0,01217998 ! cell aging GO:0007569 13 13 1,000 1,044E-03 0,01210338 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 1,044E-03 0,01202773 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 1,044E-03 0,01195303 ! regulation of peptide secretion GO:0002791 13 13 1,000 1,044E-03 0,01187924 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 1,044E-03 0,01180636 ! cell-cell junction organization GO:0045216 13 13 1,000 1,044E-03 0,01173437 ! microtubule cytoskeleton organization GO:0000226 55 55 2,000 1,104E-03 0,01232626 ! protein amino acid acylation GO:0043543 14 14 1,000 1,215E-03 0,01349376 ! base-excision repair GO:0006284 14 14 1,000 1,215E-03 0,01341296 ! positive regulation of inflammatory response GO:0050729 14 14 1,000 1,215E-03 0,01333312 ! regulation of protein localization GO:0032880 58 57 2,000 1,225E-03 0,01335509 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 1,399E-03 0,01516809 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 1,399E-03 0,01507939 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 1,399E-03 0,01499172 ! response to starvation GO:0042594 15 15 1,000 1,399E-03 0,01490506 ! response to ionizing radiation GO:0010212 16 15 1,000 1,399E-03 0,0148194 ! negative regulation of transcription factor activity GO:0043433 16 15 1,000 1,399E-03 0,01473471 GO:0090048|negative regulation of transcription regulator activity, ! negative regulation of cell activation GO:0050866 15 15 1,000 1,399E-03 0,01465099 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 2,000 1,491E-03 0,0155281 ! axonogenesis GO:0007409 66 62 2,000 1,563E-03 0,01618542 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 1,000 1,595E-03 0,01642516 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 1,000 1,595E-03 0,01633391 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 1,595E-03 0,01624367 ! segmentation GO:0035282 17 16 1,000 1,595E-03 0,01615442 ! triglyceride metabolic process GO:0006641 16 16 1,000 1,595E-03 0,01606614 ! cell fate specification GO:0001708 16 16 1,000 1,595E-03 0,01597883 ! cellular response to nutrient levels GO:0031669 16 16 1,000 1,595E-03 0,01589245 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 1,000 1,595E-03 0,01580701 ! positive regulation of catabolic process GO:0009896 16 16 1,000 1,595E-03 0,01572248 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 1,804E-03 0,01768291 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 1,804E-03 0,01758935 ! myelination GO:0042552 17 17 1,000 1,804E-03 0,01749677 ! leukocyte adhesion GO:0007159 17 17 1,000 1,804E-03 0,01740517 ! negative regulation of cell development GO:0010721 18 17 1,000 1,804E-03 0,01731451 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 1,804E-03 0,0172248 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 2,000 1,955E-03 0,01857662 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! striated muscle tissue development GO:0014706 69 67 2,000 1,955E-03 0,01848136 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 2,025E-03 0,01903704 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 2,025E-03 0,0189404 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 2,025E-03 0,01884474 ! neutral lipid metabolic process GO:0006638 18 18 1,000 2,025E-03 0,01875004 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 1,000 2,025E-03 0,01865629 ! B cell differentiation GO:0030183 18 18 1,000 2,025E-03 0,01856348 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 2,025E-03 0,01847158 ! ensheathment of neurons GO:0007272 18 18 1,000 2,025E-03 0,01838059 GO:0008366|axon ensheathment, ! regulation of microtubule-based process GO:0032886 18 18 1,000 2,025E-03 0,01829048 ! negative regulation of catabolic process GO:0009895 18 18 1,000 2,025E-03 0,01820126 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 2,025E-03 0,01811291 ! response to radiation GO:0009314 70 68 2,000 2,041E-03 0,01816799 ! regulation of mitotic cell cycle GO:0007346 72 69 2,000 2,128E-03 0,01885525 ! positive regulation of transport GO:0051050 71 70 2,000 2,218E-03 0,01955627 ! cell part morphogenesis GO:0032990 75 70 2,000 2,218E-03 0,01946314 ! wound healing GO:0042060 74 70 2,000 2,218E-03 0,0193709 ! muscle tissue development GO:0060537 72 70 2,000 2,218E-03 0,01927953 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 2,257E-03 0,01953314 ! regulation of pH GO:0006885 19 19 1,000 2,257E-03 0,01944186 ! regulation of JAK-STAT cascade GO:0046425 19 19 1,000 2,257E-03 0,01935143 ! peripheral nervous system development GO:0007422 19 19 1,000 2,257E-03 0,01926184 ! regulation of protein stability GO:0031647 19 19 1,000 2,257E-03 0,01917308 ! regulation of cell migration GO:0030334 71 71 2,000 2,31E-03 0,01952714 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 2,404E-03 0,02023242 ! negative regulation of binding GO:0051100 21 20 1,000 2,503E-03 0,02096419 ! organic ether metabolic process GO:0018904 20 20 1,000 2,503E-03 0,02086933 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 1,000 2,503E-03 0,02077533 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 2,503E-03 0,02068216 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 2,76E-03 0,02270442 ! mammary gland development GO:0030879 23 21 1,000 2,76E-03 0,02260351 ! Notch signaling pathway GO:0007219 22 21 1,000 2,76E-03 0,02250349 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 2,76E-03 0,02240436 ! regulation of action potential in neuron GO:0019228 21 21 1,000 2,76E-03 0,0223061 ! regulation of multicellular organism growth GO:0040014 21 21 1,000 2,76E-03 0,02220869 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 1,000 2,76E-03 0,02211213 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 2,76E-03 0,02201641 ! negative regulation of protein transport GO:0051224 21 21 1,000 2,76E-03 0,02192151 ! regulation of protein modification process GO:0031399 79 78 2,000 3,021E-03 0,02389618 ! microtubule-based movement GO:0007018 82 78 2,000 3,021E-03 0,02379406 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 3,028E-03 0,02375064 GO:0090047|positive regulation of transcription regulator activity, ! hormone-mediated signaling GO:0009755 22 22 1,000 3,028E-03 0,02365 ! maintenance of protein location in cell GO:0032507 23 22 1,000 3,028E-03 0,02355021 ! spindle organization GO:0007051 22 22 1,000 3,028E-03 0,02345126 ! regulation of locomotion GO:0040012 79 79 2,000 3,132E-03 0,02415539 ! regulation of cell motion GO:0051270 79 79 2,000 3,132E-03 0,02405474 ! neuron projection development GO:0031175 85 80 2,000 3,246E-03 0,02482608 ! regulation of hormone secretion GO:0046883 23 23 1,000 3,309E-03 0,02520163 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 3,309E-03 0,02509792 ! endocrine system development GO:0035270 23 23 1,000 3,309E-03 0,02499506 ! positive regulation of growth GO:0045927 23 23 1,000 3,309E-03 0,02489304 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 3,309E-03 0,02479185 ! calcium-mediated signaling GO:0019722 23 23 1,000 3,309E-03 0,02469148 ! tube development GO:0035295 83 81 2,000 3,363E-03 0,02499068 ! mitochondrial transport GO:0006839 24 24 1,000 3,602E-03 0,02665789 ! regulation of action potential GO:0001508 24 24 1,000 3,602E-03 0,02655126 ! T cell differentiation GO:0030217 24 24 1,000 3,602E-03 0,02644547 ! maintenance of protein location GO:0045185 25 24 1,000 3,602E-03 0,02634053 ! androgen receptor signaling pathway GO:0030521 24 24 1,000 3,602E-03 0,02623642 ! regulation of cellular localization GO:0060341 86 85 2,000 3,854E-03 0,02796581 ! negative regulation of secretion GO:0051048 26 25 1,000 3,906E-03 0,02822863 ! endosome transport GO:0016197 25 25 1,000 3,906E-03 0,02811836 ! regulation of T cell proliferation GO:0042129 25 25 1,000 3,906E-03 0,02800895 ! heart morphogenesis GO:0003007 25 25 1,000 3,906E-03 0,02790039 ! icosanoid metabolic process GO:0006690 25 25 1,000 3,906E-03 0,02779266 ! negative regulation of immune system process GO:0002683 25 25 1,000 3,906E-03 0,02768577 ! positive regulation of defense response GO:0031349 26 26 1,000 4,221E-03 0,02980879 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 1,000 4,221E-03 0,02969502 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 4,221E-03 0,02958211 ! regulation of T cell differentiation GO:0045580 26 26 1,000 4,221E-03 0,02947005 ! double-strand break repair GO:0006302 27 26 1,000 4,221E-03 0,02935885 ! maintenance of location in cell GO:0051651 27 26 1,000 4,221E-03 0,02924848 ! synapse organization GO:0050808 26 26 1,000 4,221E-03 0,02913893 ! learning or memory GO:0007611 28 27 1,000 4,549E-03 0,03128001 ! cAMP-mediated signaling GO:0019933 27 27 1,000 4,549E-03 0,03116373 ! activation of caspase activity GO:0006919 27 27 1,000 4,549E-03 0,03104831 ! mesenchymal cell development GO:0014031 29 27 1,000 4,549E-03 0,03093374 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! negative regulation of cell cycle GO:0045786 92 91 2,000 4,67E-03 0,03164301 ! unsaturated fatty acid metabolic process GO:0033559 28 28 1,000 4,887E-03 0,03299263 ! histone modification GO:0016570 28 28 1,000 4,887E-03 0,03287222 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 4,887E-03 0,03275269 ! positive regulation of cell cycle GO:0045787 29 29 1,000 5,237E-03 0,03497021 ! viral reproductive process GO:0022415 29 29 1,000 5,237E-03 0,03484396 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 5,237E-03 0,03471862 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! covalent chromatin modification GO:0016569 29 29 1,000 5,237E-03 0,03459418 ! positive regulation of protein transport GO:0051222 29 29 1,000 5,237E-03 0,03447063 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 5,598E-03 0,03671621 GO:0043280|positive regulation of caspase activity, ! activation of phospholipase C activity GO:0007202 30 30 1,000 5,598E-03 0,03658601 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 5,598E-03 0,03645673 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 1,000 5,598E-03 0,03632836 ! regulation of inflammatory response GO:0050727 30 30 1,000 5,598E-03 0,03620089 ! skeletal muscle fiber development GO:0048741 31 31 1,000 5,97E-03 0,03847296 ! B cell activation GO:0042113 31 31 1,000 5,97E-03 0,03833891 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 5,97E-03 0,03820579 ! aging GO:0007568 32 31 1,000 5,97E-03 0,03807359 ! muscle organ development GO:0007517 102 100 2,000 6,078E-03 0,03862538 ! negative regulation of cell growth GO:0030308 32 32 1,000 6,354E-03 0,04023939 ! muscle fiber development GO:0048747 32 32 1,000 6,354E-03 0,04010158 ! regulation of phospholipase activity GO:0010517 32 32 1,000 6,354E-03 0,03996472 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 6,354E-03 0,03982878 ! positive regulation of lipase activity GO:0060193 32 32 1,000 6,354E-03 0,03969377 ! maintenance of location GO:0051235 33 32 1,000 6,354E-03 0,03955967 ! negative regulation of cell size GO:0045792 33 33 1,000 6,748E-03 0,04187303 ! activation of protein kinase activity GO:0032147 35 33 1,000 6,748E-03 0,04173251 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 6,748E-03 0,04159294 ! regulation of angiogenesis GO:0045765 35 34 1,000 7,153E-03 0,04394332 ! regulation of protein catabolic process GO:0042176 35 34 1,000 7,153E-03 0,04379733 ! viral reproduction GO:0016032 34 34 1,000 7,153E-03 0,04365231 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 7,569E-03 0,0460384 ! multicellular organism reproduction GO:0032504 36 35 1,000 7,569E-03 0,04588696 GO:0048609|reproductive process in a multicellular organism, ! regulation of lipase activity GO:0060191 36 36 1,000 7,996E-03 0,04831493 ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 8,433E-03 0,0507912 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 8,433E-03 0,05062575 ! response to drug GO:0042493 37 37 1,000 8,433E-03 0,05046138 ! lymphocyte mediated immunity GO:0002449 37 37 1,000 8,433E-03 0,05029808 ! negative regulation of growth GO:0045926 37 37 1,000 8,433E-03 0,05013583 ! positive regulation of secretion GO:0051047 39 38 1,000 8,881E-03 0,05262908 ! negative regulation of kinase activity GO:0033673 38 38 1,000 8,881E-03 0,05246039 ! cell-matrix adhesion GO:0007160 39 38 1,000 8,881E-03 0,05229279 ! axon guidance GO:0007411 39 38 1,000 8,881E-03 0,05212625 ! steroid hormone receptor signaling pathway GO:0030518 38 38 1,000 8,881E-03 0,05196077 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 9,339E-03 0,05446999 ! positive regulation of protein modification process GO:0031401 39 39 1,000 9,339E-03 0,05429816 ! nucleotide-excision repair GO:0006289 40 39 1,000 9,339E-03 0,05412741 ! lymphocyte differentiation GO:0030098 39 39 1,000 9,339E-03 0,05395773 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 9,808E-03 0,05648932 ! negative regulation of transferase activity GO:0051348 40 40 1,000 9,808E-03 0,05631334 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 1,000 9,808E-03 0,05613846 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,01028741 0,05869875 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of caspase activity GO:0043281 41 41 1,000 0,01028741 0,05851758 ! leukocyte mediated immunity GO:0002443 41 41 1,000 0,01028741 0,05833752 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,01077684 0,06092548 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,01077684 0,06073917 ! cell-substrate adhesion GO:0031589 43 42 1,000 0,01077684 0,06055399 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 1,000 0,01127644 0,06316863 ! mitochondrion organization GO:0007005 44 43 1,000 0,01127644 0,06297721 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,01127644 0,06278694 ! protein import into nucleus GO:0006606 44 44 1,000 0,01178614 0,0654273 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,01230587 0,06810726 ! nuclear import GO:0051170 45 45 1,000 0,01230587 0,06790335 ! Wnt receptor signaling pathway GO:0016055 46 45 1,000 0,01230587 0,06770065 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 1,000 0,01283554 0,07040447 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,01283554 0,07019556 ! regulation of membrane potential GO:0042391 46 46 1,000 0,01283554 0,06998788 ! actin filament organization GO:0007015 50 48 1,000 0,01392442 0,07570118 ! protein localization in nucleus GO:0034504 48 48 1,000 0,01392442 0,07547853 ! leukocyte differentiation GO:0002521 50 49 1,000 0,01448347 0,07827868 ! ossification GO:0001503 50 49 1,000 0,01448347 0,0780498 GO:0060348|bone development, ! gland development GO:0048732 51 49 1,000 0,01448347 0,07782225 ! regulation of defense response GO:0031347 50 50 1,000 0,01505216 0,08064282 ! T cell activation GO:0042110 51 50 1,000 0,01505216 0,08040908 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,01505216 0,08017668 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,01505216 0,07994562 ! response to hypoxia GO:0001666 53 53 1,000 0,01681534 0,08905366 ! regulation of T cell activation GO:0050863 53 53 1,000 0,01681534 0,0887985 ! protein amino acid dephosphorylation GO:0006470 55 54 1,000 0,01742186 0,09173852 ! response to oxygen levels GO:0070482 55 54 1,000 0,01742186 0,09147715 ! hormone metabolic process GO:0042445 55 54 1,000 0,01742186 0,09121728 ! in utero embryonic development GO:0001701 55 55 1,000 0,01803764 0,09417386 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,01803764 0,09390783 ! reproductive developmental process GO:0003006 56 56 1,000 0,01866262 0,09688794 ! extracellular structure organization GO:0043062 56 56 1,000 0,01866262 0,09661578 ! regulation of nervous system development GO:0051960 57 56 1,000 0,01866262 0,09634515 ! rRNA transcription GO:0009303 5 5 0,000 0,01875849 0,09656953 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,01875849 0,09630053 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,01875849 0,09603303 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,01875849 0,09576701 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,01875849 0,09550246 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,01875849 0,09523937 ! reproductive cellular process GO:0048610 5 5 0,000 0,01875849 0,09497772 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,01875849 0,09471751 ! prostate gland development GO:0030850 5 5 0,000 0,01875849 0,09445872 ! metencephalon development GO:0022037 5 5 0,000 0,01875849 0,09420134 ! water transport GO:0006833 5 5 0,000 0,01875849 0,09394535 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,01875849 0,09369076 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,01875849 0,09343754 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,01875849 0,09318569 ! glycerol metabolic process GO:0006071 5 5 0,000 0,01875849 0,09293519 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,01875849 0,09268603 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,01875849 0,09243821 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,01875849 0,09219171 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,01875849 0,09194652 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,01875849 0,09170263 ! filopodium assembly GO:0046847 7 5 0,000 0,01875849 0,09146003 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,01875849 0,09121871 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,01875849 0,09097866 ! GTP metabolic process GO:0046039 5 5 0,000 0,01875849 0,09073987 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,01875849 0,09050233 ! mRNA stabilization GO:0048255 5 5 0,000 0,01875849 0,09026603 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,01875849 0,09003096 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,01875849 0,08979712 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,01875849 0,08956448 ! social behavior GO:0035176 5 5 0,000 0,01875849 0,08933305 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,01875849 0,08910281 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,01875849 0,08887375 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,01875849 0,08864587 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,01875849 0,08841916 ! response to lipid GO:0033993 5 5 0,000 0,01875849 0,0881936 ! erythrocyte maturation GO:0043249 5 5 0,000 0,01875849 0,08796919 ! hippocampus development GO:0021766 6 5 0,000 0,01875849 0,08774592 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,01875849 0,08752377 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,01875849 0,08730275 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,01875849 0,08708285 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,01875849 0,08686405 ! mechanosensory behavior GO:0007638 5 5 0,000 0,01875849 0,08664634 ! heart looping GO:0001947 5 5 0,000 0,01875849 0,08642973 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,01875849 0,08621419 ! response to interferon-gamma GO:0034341 5 5 0,000 0,01875849 0,08599973 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,01875849 0,08578633 ! pH reduction GO:0045851 5 5 0,000 0,01875849 0,08557399 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,01875849 0,08536269 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,01875849 0,08515244 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,01875849 0,08494322 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,01875849 0,08473503 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,01875849 0,08452785 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,01875849 0,08432168 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,01875849 0,08411652 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,01875849 0,08391236 ! adrenal gland development GO:0030325 5 5 0,000 0,01875849 0,08370918 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,01875849 0,08350698 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,01875849 0,08330576 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,01875849 0,08310551 ! astrocyte differentiation GO:0048708 5 5 0,000 0,01875849 0,08290621 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,01875849 0,08270787 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,01875849 0,08251048 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,01875849 0,08231403 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,01875849 0,0821185 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,01875849 0,08192391 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,01875849 0,08173024 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,01875849 0,08153748 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,01875849 0,08134562 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,01875849 0,08115467 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,01875849 0,08096461 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,01875849 0,08077545 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,01875849 0,08058716 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,01875849 0,08039975 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,01875849 0,0802132 ! response to ATP GO:0033198 5 5 0,000 0,01875849 0,08002752 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,01875849 0,0798427 ! regulation of appetite GO:0032098 5 5 0,000 0,01875849 0,07965873 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,01875849 0,07947561 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,01875849 0,07929333 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,01875849 0,07911188 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,01875849 0,07893126 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01875849 0,07875146 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,01875849 0,07857248 ! fear response GO:0042596 5 5 0,000 0,01875849 0,07839431 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,01875849 0,07821695 ! retinol metabolic process GO:0042572 5 5 0,000 0,01875849 0,07804038 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,01875849 0,07786462 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,01875849 0,07768964 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,01875849 0,07751545 ! parturition GO:0007567 5 5 0,000 0,01875849 0,07734204 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01875849 0,0771694 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,01875849 0,07699753 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,01875849 0,07682642 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,01875849 0,07665608 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,01875849 0,07648648 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,01875849 0,07631764 ! response to UV-B GO:0010224 5 5 0,000 0,01875849 0,07614954 ! oligodendrocyte development GO:0014003 5 5 0,000 0,01875849 0,07598218 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,01875849 0,07581555 ! activated T cell proliferation GO:0050798 5 5 0,000 0,01875849 0,07564965 ! interaction with symbiont GO:0051702 5 5 0,000 0,01875849 0,07548448 ! cellular extravasation GO:0045123 5 5 0,000 0,01875849 0,07532002 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,01875849 0,07515628 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,01875849 0,07499325 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,01875849 0,07483093 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,01875849 0,07466931 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,01875849 0,07450838 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,01875849 0,07434815 ! response to amine stimulus GO:0014075 5 5 0,000 0,01875849 0,07418861 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,01875849 0,07402974 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,01875849 0,07387156 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,01875849 0,07371405 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,01875849 0,07355721 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,01875849 0,07340104 ! neuron recognition GO:0008038 5 5 0,000 0,01875849 0,07324553 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,01875849 0,07309068 ! decidualization GO:0046697 5 5 0,000 0,01875849 0,07293648 ! hair follicle maturation GO:0048820 5 5 0,000 0,01875849 0,07278293 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,01875849 0,07263002 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,01875849 0,07247776 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,01875849 0,07232613 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,01875849 0,07217514 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,01875849 0,07202477 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,01875849 0,07187503 ! postreplication repair GO:0006301 5 5 0,000 0,01875849 0,07172591 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,01875849 0,07157741 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,01875849 0,07142953 ! histone methylation GO:0016571 5 5 0,000 0,01875849 0,07128225 ! DNA methylation GO:0006306 5 5 0,000 0,01875849 0,07113558 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01875849 0,07098951 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,01875849 0,07084404 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,01875849 0,07069916 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,01875849 0,07055488 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,01875849 0,07041118 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,01875849 0,07026807 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,01875849 0,07012554 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,01875849 0,06998358 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,01875849 0,0698422 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,01875849 0,06970139 ! sterol catabolic process GO:0016127 5 5 0,000 0,01875849 0,06956115 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,01875849 0,06942147 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,01875849 0,06928235 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,01875849 0,06914378 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,01875849 0,06900577 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,01875849 0,06886831 ! zymogen activation GO:0031638 5 5 0,000 0,01875849 0,06873139 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,01875849 0,06859502 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,01875849 0,06845919 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,01875849 0,06832389 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,01875849 0,06818913 ! nucleosome positioning GO:0016584 5 5 0,000 0,01875849 0,0680549 ! regulation of isotype switching GO:0045191 5 5 0,000 0,01875849 0,0679212 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,01875849 0,06778802 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,01875849 0,06765536 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,01875849 0,06752322 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,01875849 0,0673916 ! NADPH regeneration GO:0006740 5 5 0,000 0,01875849 0,06726049 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,01875849 0,06712988 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,01875849 0,06699979 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,01875849 0,06687019 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,01875849 0,0667411 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,01875849 0,06661251 ! sarcomere organization GO:0045214 5 5 0,000 0,01875849 0,0664844 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,01875849 0,0663568 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,01875849 0,06622968 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,01875849 0,06610304 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,01875849 0,06597689 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,01875849 0,06585122 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,01875849 0,06572603 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,01875849 0,06560131 ! spleen development GO:0048536 5 5 0,000 0,01875849 0,06547707 ! male genitalia development GO:0030539 5 5 0,000 0,01875849 0,06535329 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,01875849 0,06522998 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,01875849 0,06510714 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,01875849 0,06498476 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,01875849 0,06486283 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,01875849 0,06474137 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,01875849 0,06462036 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,01875849 0,0644998 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,01875849 0,06437968 ! ATP catabolic process GO:0006200 5 5 0,000 0,01875849 0,06426002 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01875849 0,0641408 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,01875849 0,06402202 ! blastocyst formation GO:0001825 5 5 0,000 0,01875849 0,06390368 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,01875849 0,06378578 ! embryonic gut development GO:0048566 5 5 0,000 0,01875849 0,06366831 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,01875849 0,06355127 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,01875849 0,06343466 ! activation of innate immune response GO:0002218 5 5 0,000 0,01875849 0,06331848 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,01875849 0,06320272 ! catecholamine transport GO:0051937 5 5 0,000 0,01875849 0,06308739 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,01875849 0,06297248 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,01875849 0,06285798 ! muscle adaptation GO:0043500 5 5 0,000 0,01875849 0,0627439 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,01875849 0,06263024 ! embryonic heart tube development GO:0035050 5 5 0,000 0,01875849 0,06251698 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,01875849 0,06240413 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,01875849 0,06229169 ! defense response to fungus GO:0050832 5 5 0,000 0,01875849 0,06217966 ! lysogeny GO:0030069 5 5 0,000 0,01875849 0,06206803 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,01875849 0,06195679 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,01875849 0,06184596 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,01875849 0,06173552 ! response to nicotine GO:0035094 5 5 0,000 0,01875849 0,06162547 ! establishment of cell polarity GO:0030010 5 5 0,000 0,01875849 0,06151582 ! mitochondrion localization GO:0051646 5 5 0,000 0,01875849 0,06140656 ! nucleus localization GO:0051647 5 5 0,000 0,01875849 0,06129768 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,01875849 0,06118919 ! innate immune response GO:0045087 58 58 1,000 0,01993989 0,06492796 ! dephosphorylation GO:0016311 60 59 1,000 0,02059204 0,0669332 ! regulation of cell development GO:0060284 60 59 1,000 0,02059204 0,06681536 ! protein localization in organelle GO:0033365 59 59 1,000 0,02059204 0,06669794 ! immune effector process GO:0002252 59 59 1,000 0,02059204 0,06658092 ! protein polymerization GO:0051258 65 60 1,000 0,02125309 0,06859798 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 0,02192298 0,07063646 ! axon extension GO:0048675 7 6 0,000 0,02246936 0,07227057 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,02246936 0,07214466 ! tRNA modification GO:0006400 6 6 0,000 0,02246936 0,07201919 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,02246936 0,07189416 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,02246936 0,07176956 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,02246936 0,07164539 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,02246936 0,07152165 ! regulation of S phase GO:0033261 6 6 0,000 0,02246936 0,07139834 ! myotube differentiation GO:0014902 6 6 0,000 0,02246936 0,07127545 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,02246936 0,07115298 ! bone remodeling GO:0046849 6 6 0,000 0,02246936 0,07103094 ! N-glycan processing GO:0006491 6 6 0,000 0,02246936 0,07090931 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,02246936 0,0707881 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,02246936 0,0706673 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,02246936 0,07054691 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,02246936 0,07042693 ! RNA methylation GO:0001510 6 6 0,000 0,02246936 0,07030736 ! cartilage condensation GO:0001502 7 6 0,000 0,02246936 0,0701882 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,02246936 0,07006944 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,02246936 0,06995108 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,02246936 0,06983311 ! artery development GO:0060840 6 6 0,000 0,02246936 0,06971555 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,02246936 0,06959838 ! bile acid metabolic process GO:0008206 6 6 0,000 0,02246936 0,06948161 ! androgen metabolic process GO:0008209 6 6 0,000 0,02246936 0,06936522 ! estrogen metabolic process GO:0008210 6 6 0,000 0,02246936 0,06924923 ! limbic system development GO:0021761 7 6 0,000 0,02246936 0,06913362 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,02246936 0,06901839 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,02246936 0,06890356 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,02246936 0,0687891 ! pathogenesis GO:0009405 6 6 0,000 0,02246936 0,06867502 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,02246936 0,06856132 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,02246936 0,06844799 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,02246936 0,06833504 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,02246936 0,06822247 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,02246936 0,06811026 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,02246936 0,06799842 ! arginine metabolic process GO:0006525 6 6 0,000 0,02246936 0,06788695 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,02246936 0,06777584 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,02246936 0,06766509 ! glutamate catabolic process GO:0006538 7 6 0,000 0,02246936 0,06755471 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,02246936 0,06744469 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,02246936 0,06733502 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,02246936 0,06722571 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,02246936 0,06711675 ! V(D)J recombination GO:0033151 6 6 0,000 0,02246936 0,06700815 ! focal adhesion formation GO:0048041 7 6 0,000 0,02246936 0,0668999 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,02246936 0,06679199 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,02246936 0,06668444 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,02246936 0,06657723 ! regulation of heart rate GO:0002027 6 6 0,000 0,02246936 0,06647036 ! lipid digestion GO:0044241 6 6 0,000 0,02246936 0,06636384 ! asymmetric protein localization GO:0008105 6 6 0,000 0,02246936 0,06625766 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,02246936 0,06615182 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,02246936 0,06604631 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,02246936 0,06594114 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,02246936 0,06583631 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,02246936 0,0657318 ! ruffle organization GO:0031529 6 6 0,000 0,02246936 0,06562763 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,02246936 0,06552379 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,02246936 0,06542028 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,02246936 0,06531709 ! neutral amino acid transport GO:0015804 6 6 0,000 0,02246936 0,06521423 ! L-amino acid transport GO:0015807 6 6 0,000 0,02246936 0,06511169 ! bone mineralization GO:0030282 6 6 0,000 0,02246936 0,06500948 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,02246936 0,06490758 ! negative regulation of ossification GO:0030279 6 6 0,000 0,02246936 0,064806 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,02246936 0,06470475 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,02246936 0,0646038 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,02246936 0,06450317 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,02246936 0,06440286 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,02246936 0,06430285 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,02246936 0,06420316 ! regulation of organ growth GO:0046620 6 6 0,000 0,02246936 0,06410377 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,02246936 0,06400469 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,02246936 0,06390592 ! response to dsRNA GO:0043331 6 6 0,000 0,02246936 0,06380745 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,02246936 0,06370929 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,02246936 0,06361142 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,02246936 0,06351386 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,02246936 0,0634166 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,02246936 0,06331963 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,02246936 0,06322296 ! multicellular organismal aging GO:0010259 6 6 0,000 0,02246936 0,06312658 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,02246936 0,0630305 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,02246936 0,06293471 ! erythrocyte development GO:0048821 6 6 0,000 0,02246936 0,06283921 ! renal water homeostasis GO:0003091 6 6 0,000 0,02246936 0,062744 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,02246936 0,06264907 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,02246936 0,06255444 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,02246936 0,06246009 ! ribosome assembly GO:0042255 6 6 0,000 0,02246936 0,06236602 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,02246936 0,06227224 ! diencephalon development GO:0021536 6 6 0,000 0,02246936 0,06217873 ! fucose catabolic process GO:0019317 6 6 0,000 0,02246936 0,06208551 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,02246936 0,06199257 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,02246936 0,06189991 ! regulation of lipid transport GO:0032368 6 6 0,000 0,02246936 0,06180752 ! regulation of cell division GO:0051302 6 6 0,000 0,02246936 0,06171541 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,02246936 0,06162357 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,02246936 0,061532 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,02246936 0,06144071 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,02246936 0,06134968 ! neuroblast proliferation GO:0007405 6 6 0,000 0,02246936 0,06125893 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,02246936 0,06116844 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,02246936 0,06107823 ! regulation of glucose transport GO:0010827 6 6 0,000 0,02246936 0,06098827 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,02246936 0,06089858 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,02246936 0,06080916 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,02246936 0,06072 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,02246936 0,06063109 ! thymus development GO:0048538 6 6 0,000 0,02246936 0,06054245 ! lymph node development GO:0048535 6 6 0,000 0,02246936 0,06045407 ! organic cation transport GO:0015695 6 6 0,000 0,02246936 0,06036594 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,02246936 0,06027807 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,02246936 0,06019046 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,02246936 0,0601031 ! sperm-egg recognition GO:0035036 7 6 0,000 0,02246936 0,060016 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,02246936 0,05992914 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,02246936 0,05984254 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,02246936 0,05975619 ! alditol metabolic process GO:0019400 6 6 0,000 0,02246936 0,05967008 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,02246936 0,05958423 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,02246936 0,05949862 ! maternal placenta development GO:0001893 6 6 0,000 0,02246936 0,05941325 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,02246936 0,05932813 ! protein import GO:0017038 62 62 1,000 0,02260164 0,05959202 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,02260164 0,05950689 ! regulation of secretion GO:0051046 65 63 1,000 0,023289 0,06122913 ! glycerolipid metabolic process GO:0046486 65 64 1,000 0,02398498 0,06296911 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,02398498 0,06287954 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 0,02398498 0,06279023 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,02398498 0,06270116 ! regulation of hormone levels GO:0010817 66 65 1,000 0,02468952 0,06445154 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 0,02540255 0,0662191 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,026124 0,06800358 ! respiratory burst GO:0045730 7 7 0,000 0,02616674 0,06801877 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,02616674 0,06792297 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,02616674 0,06782744 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,02616674 0,06773218 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,02616674 0,06763718 ! regulation of chemokine production GO:0032642 7 7 0,000 0,02616674 0,06754245 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,02616674 0,06744799 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,02616674 0,06735378 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,02616674 0,06725985 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,02616674 0,06716617 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,02616674 0,06707275 ! gene silencing by RNA GO:0031047 7 7 0,000 0,02616674 0,0669796 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,02616674 0,0668867 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,02616674 0,06679406 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,02616674 0,06670167 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,02616674 0,06660954 ! axis specification GO:0009798 7 7 0,000 0,02616674 0,06651767 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,02616674 0,06642605 ! visual behavior GO:0007632 7 7 0,000 0,02616674 0,06633468 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,02616674 0,06624356 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,02616674 0,06615269 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,02616674 0,06606207 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,02616674 0,0659717 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,02616674 0,06588157 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,02616674 0,06579169 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,02616674 0,06570206 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,02616674 0,06561267 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,02616674 0,06552352 ! digestive system development GO:0055123 7 7 0,000 0,02616674 0,06543461 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,02616674 0,06534595 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,02616674 0,06525752 ! protein targeting to ER GO:0045047 8 7 0,000 0,02616674 0,06516934 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,02616674 0,06508139 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,02616674 0,06499368 ! endoderm development GO:0007492 7 7 0,000 0,02616674 0,0649062 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,02616674 0,06481896 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,02616674 0,06473196 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,02616674 0,06464519 ! response to hexose stimulus GO:0009746 7 7 0,000 0,02616674 0,06455865 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,02616674 0,06447234 GO:0033619|membrane protein proteolysis, ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,02616674 0,06438626 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,02616674 0,06430041 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,02616674 0,06421479 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,02616674 0,0641294 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,02616674 0,06404424 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,02616674 0,0639593 ! UV protection GO:0009650 7 7 0,000 0,02616674 0,06387458 ! DNA integration GO:0015074 7 7 0,000 0,02616674 0,06379009 ! myofibril assembly GO:0030239 7 7 0,000 0,02616674 0,06370583 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,02616674 0,06362178 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,02616674 0,06353796 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,02616674 0,06345436 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,02616674 0,06337097 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,02616674 0,06328781 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,02616674 0,06320486 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,02616674 0,06312213 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,02616674 0,06303962 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,02616674 0,06295732 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,02616674 0,06287524 ! eating behavior GO:0042755 7 7 0,000 0,02616674 0,06279337 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,02616674 0,06271172 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,02616674 0,06263027 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,02616674 0,06254904 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,02616674 0,06246802 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,02616674 0,06238721 ! cranial nerve development GO:0021545 7 7 0,000 0,02616674 0,0623066 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,02616674 0,06222621 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,02616674 0,06214602 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,02616674 0,06206604 ! autonomic nervous system development GO:0048483 7 7 0,000 0,02616674 0,06198626 ! intracellular lipid transport GO:0032365 7 7 0,000 0,02616674 0,06190669 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,02616674 0,06182732 ! platelet activation GO:0030168 8 7 0,000 0,02616674 0,06174816 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,02616674 0,06166919 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,02616674 0,06159043 ! natural killer cell activation GO:0030101 7 7 0,000 0,02616674 0,06151187 ! NADP metabolic process GO:0006739 7 7 0,000 0,02616674 0,06143352 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,02616674 0,06135536 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,02616674 0,0612774 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,02616674 0,06119963 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,02616674 0,06112207 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,02616674 0,0610447 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,02616674 0,06096752 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,02616674 0,06089054 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,02616674 0,06081376 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,02616674 0,06073717 ! cell-cell recognition GO:0009988 8 7 0,000 0,02616674 0,06066077 ! hormone catabolic process GO:0042447 7 7 0,000 0,02616674 0,06058456 ! dopamine metabolic process GO:0042417 7 7 0,000 0,02616674 0,06050854 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,02616674 0,06043272 ! oxygen transport GO:0015671 7 7 0,000 0,02616674 0,06035708 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,02616674 0,06028164 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,02616674 0,06020638 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,02616674 0,06013131 ! regulation of axon extension GO:0030516 7 7 0,000 0,02616674 0,06005643 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,02616674 0,05998173 ! adult feeding behavior GO:0008343 7 7 0,000 0,02616674 0,05990722 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,02616674 0,05983289 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,02616674 0,05975875 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,02616674 0,05968479 ! response to cold GO:0009409 7 7 0,000 0,02616674 0,05961101 ! regulation of cell size GO:0008361 68 68 1,000 0,0268538 0,06110069 ! sensory perception of sound GO:0007605 71 69 1,000 0,02759189 0,06270265 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 1,000 0,02759189 0,06262543 ! response to nutrient levels GO:0031667 69 69 1,000 0,02759189 0,0625484 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,02759189 0,06247156 ! growth GO:0040007 70 70 1,000 0,02833819 0,06408255 ! regulation of cell activation GO:0050865 71 71 1,000 0,02909263 0,06570799 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,02985068 0,06733757 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,02985068 0,06725525 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,02985068 0,06717313 ! positive regulation of translation GO:0045727 8 8 0,000 0,02985068 0,06709122 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,02985068 0,0670095 ! superoxide anion generation GO:0042554 8 8 0,000 0,02985068 0,06692798 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,02985068 0,06684665 ! cGMP metabolic process GO:0046068 8 8 0,000 0,02985068 0,06676553 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,02985068 0,0666846 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,02985068 0,06660387 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,02985068 0,06652333 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,02985068 0,06644299 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,02985068 0,06636284 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,02985068 0,06628289 ! zinc ion transport GO:0006829 8 8 0,000 0,02985068 0,06620312 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,02985068 0,06612355 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,02985068 0,06604417 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,02985068 0,06596498 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,02985068 0,06588598 ! lipid localization GO:0010876 8 8 0,000 0,02985068 0,06580717 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,02985068 0,06572855 ! response to cAMP GO:0051591 8 8 0,000 0,02985068 0,06565012 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,02985068 0,06557187 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,02985068 0,06549381 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,02985068 0,06541593 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,02985068 0,06533824 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,02985068 0,06526073 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,02985068 0,06518341 ! sensory perception of taste GO:0050909 8 8 0,000 0,02985068 0,06510627 ! organelle fusion GO:0048284 8 8 0,000 0,02985068 0,06502931 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,02985068 0,06495253 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,02985068 0,06487594 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,02985068 0,06479952 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,02985068 0,06472329 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,02985068 0,06464723 ! sperm motility GO:0030317 8 8 0,000 0,02985068 0,06457136 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,02985068 0,06449566 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,02985068 0,06442014 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,02985068 0,06434479 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,02985068 0,06426962 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,02985068 0,06419463 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,02985068 0,06411981 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,02985068 0,06404516 ! Golgi organization GO:0007030 8 8 0,000 0,02985068 0,06397069 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,02985068 0,0638964 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,02985068 0,06382227 ! fructose metabolic process GO:0006000 8 8 0,000 0,02985068 0,06374832 ! mannose metabolic process GO:0006013 9 8 0,000 0,02985068 0,06367453 ! NAD metabolic process GO:0019674 8 8 0,000 0,02985068 0,06360092 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,02985068 0,06352748 ! plasma membrane fusion GO:0045026 8 8 0,000 0,02985068 0,06345421 ! response to fungus GO:0009620 8 8 0,000 0,02985068 0,0633811 ! stem cell differentiation GO:0048863 8 8 0,000 0,02985068 0,06330817 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,02985068 0,0632354 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,02985068 0,0631628 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,02985068 0,06309036 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,02985068 0,06301809 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,02985068 0,06294599 ! regulation of vasodilation GO:0042312 8 8 0,000 0,02985068 0,06287405 ! vasoconstriction GO:0042310 8 8 0,000 0,02985068 0,06280228 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,02985068 0,06273067 ! muscle cell development GO:0055001 8 8 0,000 0,02985068 0,06265922 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,02985068 0,06258794 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,02985068 0,06251681 ! sensory perception of pain GO:0019233 8 8 0,000 0,02985068 0,06244585 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,02985068 0,06237505 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,02985068 0,06230441 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,02985068 0,06223393 ! chromatin silencing GO:0006342 8 8 0,000 0,02985068 0,06216361 ! tissue regeneration GO:0042246 8 8 0,000 0,02985068 0,06209345 ! salivary gland development GO:0007431 8 8 0,000 0,02985068 0,06202345 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,02985068 0,0619536 ! T cell homeostasis GO:0043029 8 8 0,000 0,02985068 0,06188391 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,02985068 0,06181438 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,02985068 0,061745 ! water homeostasis GO:0030104 8 8 0,000 0,02985068 0,06167578 ! cofactor transport GO:0051181 8 8 0,000 0,02985068 0,06160672 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,02985068 0,0615378 ! acid secretion GO:0046717 8 8 0,000 0,02985068 0,06146905 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,02985068 0,06140044 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,02985068 0,06133199 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,02985068 0,06126369 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,02985068 0,06119555 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,02985068 0,06112755 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,02985068 0,06105971 ! regulation of RNA stability GO:0043487 8 8 0,000 0,02985068 0,06099201 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,02985068 0,06092447 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,02985068 0,06085708 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,02985068 0,06078983 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,02985068 0,06072273 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,02985068 0,06065578 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,02985068 0,06058898 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,02985068 0,06052233 ! peptide hormone secretion GO:0030072 8 8 0,000 0,02985068 0,06045582 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,02985068 0,06038946 ! actin filament polymerization GO:0030041 9 8 0,000 0,02985068 0,06032324 ! peptide hormone processing GO:0016486 8 8 0,000 0,02985068 0,06025717 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,02985068 0,06019124 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,02985068 0,06012546 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,02985516 0,06006884 ! lactation GO:0007595 10 9 0,000 0,03352121 0,06737141 ! embryonic pattern specification GO:0009880 10 9 0,000 0,03352121 0,06729802 ! positive regulation of cell size GO:0045793 9 9 0,000 0,03352121 0,06722479 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,03352121 0,06715172 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,03352121 0,06707881 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,03352121 0,06700606 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,03352121 0,06693346 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,03352121 0,06686102 ! viral genome replication GO:0019079 9 9 0,000 0,03352121 0,06678874 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,03352121 0,06671661 ! copper ion transport GO:0006825 9 9 0,000 0,03352121 0,06664464 ! lipid phosphorylation GO:0046834 9 9 0,000 0,03352121 0,06657283 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,03352121 0,06650117 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,03352121 0,06642966 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,03352121 0,06635831 ! RNA polyadenylation GO:0043631 9 9 0,000 0,03352121 0,06628711 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,03352121 0,06621606 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,03352121 0,06614516 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,03352121 0,06607442 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,03352121 0,06600383 ! phospholipid efflux GO:0033700 9 9 0,000 0,03352121 0,06593339 ! response to alkaloid GO:0043279 10 9 0,000 0,03352121 0,0658631 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,03352121 0,06579295 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,03352121 0,06572296 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,03352121 0,06565312 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,03352121 0,06558342 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,03352121 0,06551387 ! response to ethanol GO:0045471 9 9 0,000 0,03352121 0,06544447 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,03352121 0,06537522 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,03352121 0,06530611 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,03352121 0,06523715 ! methionine metabolic process GO:0006555 9 9 0,000 0,03352121 0,06516834 ! glutamine metabolic process GO:0006541 9 9 0,000 0,03352121 0,06509967 ! cerebral cortex development GO:0021987 9 9 0,000 0,03352121 0,06503114 ! response to osmotic stress GO:0006970 9 9 0,000 0,03352121 0,06496276 ! pigmentation during development GO:0048066 9 9 0,000 0,03352121 0,06489452 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,03352121 0,06482643 ! central nervous system neuron development GO:0021954 10 9 0,000 0,03352121 0,06475847 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,03352121 0,06469066 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,03352121 0,064623 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,03352121 0,06455547 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,03352121 0,06448808 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,03352121 0,06442084 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,03352121 0,06435373 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,03352121 0,06428677 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,03352121 0,06421994 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,03352121 0,06415325 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,03352121 0,0640867 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,03352121 0,06402029 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,03352121 0,06395402 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,03352121 0,06388788 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,03352121 0,06382188 ! DNA replication initiation GO:0006270 9 9 0,000 0,03352121 0,06375602 ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,03352121 0,06369029 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,03352121 0,0636247 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,03352121 0,06355924 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,03352121 0,06349392 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,03352121 0,06342873 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,03352121 0,06336368 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,03352121 0,06329875 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,03352121 0,06323396 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,03352121 0,06316931 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,03352121 0,06310478 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,03352121 0,06304039 ! collagen catabolic process GO:0030574 9 9 0,000 0,03352121 0,06297613 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,03352121 0,062912 ! purine base metabolic process GO:0006144 9 9 0,000 0,03352121 0,062848 ! gas transport GO:0015669 9 9 0,000 0,03352121 0,06278413 ! cholesterol efflux GO:0033344 9 9 0,000 0,03352121 0,06272039 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,03352121 0,06265678 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,03352121 0,0625933 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,03352121 0,06252994 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,03352121 0,06246672 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,03352121 0,06240362 ! defense response to virus GO:0051607 9 9 0,000 0,03352121 0,06234065 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,03352121 0,06227781 ! actin filament-based movement GO:0030048 9 9 0,000 0,03352121 0,06221509 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,03352121 0,0621525 ! nuclear transport GO:0051169 79 79 1,000 0,03541355 0,06559514 GO:0006913|nucleocytoplasmic transport, ! lymphocyte activation GO:0046649 82 81 1,000 0,03707064 0,06859556 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,03717838 0,06872593 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,03717838 0,06865707 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,03717838 0,06858835 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,03717838 0,06851976 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,03717838 0,06845131 ! neuron maturation GO:0042551 10 10 0,000 0,03717838 0,06838299 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,03717838 0,06831481 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,03717838 0,06824677 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,03717838 0,06817886 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,03717838 0,06811109 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,03717838 0,06804345 ! hormone secretion GO:0046879 10 10 0,000 0,03717838 0,06797595 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,03717838 0,06790858 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,03717838 0,06784134 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 0,000 0,03717838 0,06777424 ! inositol metabolic process GO:0006020 10 10 0,000 0,03717838 0,06770727 ! cAMP metabolic process GO:0046058 10 10 0,000 0,03717838 0,06764043 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,03717838 0,06757372 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,03717838 0,06750715 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,03717838 0,06744071 ! glial cell development GO:0021782 10 10 0,000 0,03717838 0,06737439 ! phototransduction GO:0007602 11 10 0,000 0,03717838 0,06730821 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,03717838 0,06724216 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,03717838 0,06717623 ! fat cell differentiation GO:0045444 10 10 0,000 0,03717838 0,06711044 ! myoblast differentiation GO:0045445 10 10 0,000 0,03717838 0,06704477 ! centrosome cycle GO:0007098 10 10 0,000 0,03717838 0,06697923 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,03717838 0,06691382 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,03717838 0,06684854 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,03717838 0,06678339 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,03717838 0,06671836 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,03717838 0,06665346 ! protein polyubiquitination GO:0000209 10 10 0,000 0,03717838 0,06658868 ! glutamate metabolic process GO:0006536 11 10 0,000 0,03717838 0,06652404 ! plasma membrane organization GO:0007009 10 10 0,000 0,03717838 0,06645951 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,03717838 0,06639511 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,03717838 0,06633084 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,03717838 0,06626669 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,03717838 0,06620266 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,03717838 0,06613876 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,03717838 0,06607498 ! exocrine system development GO:0035272 10 10 0,000 0,03717838 0,06601133 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,03717838 0,06594779 ! embryo implantation GO:0007566 11 10 0,000 0,03717838 0,06588438 ! regulation of protein binding GO:0043393 11 10 0,000 0,03717838 0,06582109 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,03717838 0,06575792 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,03717838 0,06569488 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,03717838 0,06563195 ! protein export from nucleus GO:0006611 10 10 0,000 0,03717838 0,06556915 ! negative regulation of immune response GO:0050777 10 10 0,000 0,03717838 0,06550646 ! cytolysis GO:0019835 10 10 0,000 0,03717838 0,06544389 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,03717838 0,06538145 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,03717838 0,06531912 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,03717838 0,06525691 ! histone deacetylation GO:0016575 10 10 0,000 0,03717838 0,06519482 ! mRNA splice site selection GO:0006376 11 10 0,000 0,03717838 0,06513285 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,03717838 0,06507099 ! gland morphogenesis GO:0022612 10 10 0,000 0,03717838 0,06500926 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,03717838 0,06494764 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,03717838 0,06488613 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,03717838 0,06482475 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,03717838 0,06476348 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,03717838 0,06470232 ! regulation of epidermis development GO:0045682 10 10 0,000 0,03717838 0,06464128 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,03717838 0,06458036 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,03717838 0,06451954 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,03717838 0,06445885 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,03717838 0,06439827 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,03717838 0,0643378 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,03717838 0,06427745 ! nerve development GO:0021675 10 10 0,000 0,03717838 0,0642172 ! gut development GO:0048565 10 10 0,000 0,03717838 0,06415708 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,03717838 0,06409706 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,03717838 0,06403716 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,03717838 0,06397736 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,03717838 0,06391768 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,03717838 0,06385811 ! blood vessel morphogenesis GO:0048514 84 83 1,000 0,03875744 0,06650835 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,04047346 0,06938846 ! protein secretion GO:0009306 11 11 0,000 0,04082225 0,06992138 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,04082225 0,06985646 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,04082225 0,06979165 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,04082225 0,06972697 ! negative regulation of defense response GO:0031348 11 11 0,000 0,04082225 0,06966241 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,04082225 0,06959797 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,04082225 0,06953364 ! skin development GO:0043588 11 11 0,000 0,04082225 0,06946944 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,04082225 0,06940535 ! endothelial cell migration GO:0043542 11 11 0,000 0,04082225 0,06934138 ! peroxisomal transport GO:0043574 11 11 0,000 0,04082225 0,06927753 ! protein amino acid methylation GO:0006479 11 11 0,000 0,04082225 0,0692138 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,04082225 0,06915019 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,04082225 0,06908669 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,04082225 0,06902331 ! T cell proliferation GO:0042098 11 11 0,000 0,04082225 0,06896004 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,04082225 0,06889689 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,04082225 0,06883385 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,04082225 0,06877093 ! spinal cord development GO:0021510 11 11 0,000 0,04082225 0,06870813 ! smooth muscle contraction GO:0006939 11 11 0,000 0,04082225 0,06864544 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,04082225 0,06858286 ! digestive system process GO:0022600 11 11 0,000 0,04082225 0,0685204 ! mitotic spindle organization GO:0007052 11 11 0,000 0,04082225 0,06845806 ! fucose metabolic process GO:0006004 11 11 0,000 0,04082225 0,06839582 ! membrane budding GO:0006900 11 11 0,000 0,04082225 0,0683337 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,04082225 0,06827169 ! monoamine transport GO:0015844 11 11 0,000 0,04082225 0,06820979 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,04082225 0,06814801 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,04082225 0,06808634 ! body fluid secretion GO:0007589 11 11 0,000 0,04082225 0,06802478 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,04082225 0,06796333 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,04082225 0,06790199 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,04082225 0,06784076 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,04082225 0,06777964 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,04082225 0,06771863 ! oogenesis GO:0048477 11 11 0,000 0,04082225 0,06765774 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,04082225 0,06759695 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,04082225 0,06753627 ! vitamin transport GO:0051180 11 11 0,000 0,04082225 0,0674757 ! muscle maintenance GO:0046716 12 11 0,000 0,04082225 0,06741524 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,04082225 0,06735488 ! hindbrain development GO:0030902 11 11 0,000 0,04082225 0,06729464 ! steroid catabolic process GO:0006706 11 11 0,000 0,04082225 0,0672345 ! endocrine process GO:0050886 11 11 0,000 0,04082225 0,06717447 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,04082225 0,06711454 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,04082225 0,06705473 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,04082225 0,06699502 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,04082225 0,06693541 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 1,000 0,04134227 0,06772782 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,04445285 0,07275898 ! translational initiation GO:0006413 12 12 0,000 0,04445285 0,07269442 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,04445285 0,07262997 ! initiation of viral infection GO:0019059 12 12 0,000 0,04445285 0,07256564 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,04445285 0,07250142 ! iron ion transport GO:0006826 13 12 0,000 0,04445285 0,07243732 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,04445285 0,07237333 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,04445285 0,07230945 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,04445285 0,07224568 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,04445285 0,07218203 ! collagen metabolic process GO:0032963 12 12 0,000 0,04445285 0,07211849 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,04445285 0,07205506 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,04445285 0,07199175 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,04445285 0,07192854 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,04445285 0,07186544 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,04445285 0,07180246 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,04445285 0,07173959 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,04445285 0,07167682 ! actomyosin structure organization GO:0031032 12 12 0,000 0,04445285 0,07161417 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,04445285 0,07155162 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,04445285 0,07148919 ! retinoid metabolic process GO:0001523 12 12 0,000 0,04445285 0,07142686 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,04445285 0,07136464 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,04445285 0,07130253 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,04445285 0,07124053 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,04445285 0,07117863 ! acute-phase response GO:0006953 12 12 0,000 0,04445285 0,07111685 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,04445285 0,07105517 ! vacuolar transport GO:0007034 12 12 0,000 0,04445285 0,07099359 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,04445285 0,07093213 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,04445285 0,07087077 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,04445285 0,07080951 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,04445285 0,07074836 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,04445285 0,07068732 ! male gonad development GO:0008584 12 12 0,000 0,04445285 0,07062638 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,04445285 0,07056555 ! renal system process GO:0003014 12 12 0,000 0,04445285 0,07050482 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,04445285 0,0704442 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,04445285 0,07038368 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,04445285 0,07032327 ! pallium development GO:0021543 13 12 0,000 0,04445285 0,07026296 ! cell fate determination GO:0001709 12 12 0,000 0,04445285 0,07020275 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,04445285 0,07014264 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,04445285 0,07008264 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,04445285 0,07002274 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,04445285 0,06996294 ! detection of light stimulus GO:0009583 13 12 0,000 0,04445285 0,06990325 ! synaptogenesis GO:0007416 12 12 0,000 0,04445285 0,06984365 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,04445285 0,06978416 ! hormone transport GO:0009914 12 12 0,000 0,04445285 0,06972477 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,04445285 0,06966548 ! heme biosynthetic process GO:0006783 12 12 0,000 0,04445285 0,06960629 ! spermatid differentiation GO:0048515 13 12 0,000 0,04445285 0,0695472 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,04445285 0,06948822 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,04445285 0,06942933 ! neural tube closure GO:0001843 13 12 0,000 0,04445285 0,06937054 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,04445285 0,06931185 ! negative regulation of translation GO:0017148 12 12 0,000 0,04445285 0,06925326 ! fatty acid metabolic process GO:0006631 93 92 1,000 0,04670241 0,0726964 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,04807024 0,07476241 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,04807024 0,07469937 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,04807024 0,07463644 ! phenol metabolic process GO:0018958 13 13 0,000 0,04807024 0,07457361 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,04807024 0,07451089 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,04807024 0,07444828 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,04807024 0,07438577 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,04807024 0,07432337 ! regeneration GO:0031099 13 13 0,000 0,04807024 0,07426107 ! keratinization GO:0031424 13 13 0,000 0,04807024 0,07419887 ! post-embryonic development GO:0009791 14 13 0,000 0,04807024 0,07413678 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,04807024 0,07407479 ! patterning of blood vessels GO:0001569 13 13 0,000 0,04807024 0,07401291 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,04807024 0,07395113 ! regulation of innate immune response GO:0045088 13 13 0,000 0,04807024 0,07388945 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,04807024 0,07382788 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,04807024 0,07376641 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,04807024 0,07370504 ! autophagy GO:0006914 13 13 0,000 0,04807024 0,07364377 ! actin filament bundle formation GO:0051017 13 13 0,000 0,04807024 0,0735826 ! ureteric bud development GO:0001657 13 13 0,000 0,04807024 0,07352154 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,04807024 0,07346058 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,04807024 0,07339971 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,04807024 0,07333895 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,04807024 0,07327829 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of viral reproduction GO:0050792 13 13 0,000 0,04807024 0,07321773 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,04807024 0,07315727 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,04807024 0,07309691 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,04807024 0,07303665 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,04807024 0,07297649 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,04807024 0,07291642 ! vasodilation GO:0042311 14 13 0,000 0,04807024 0,07285646 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,04807024 0,07279659 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,04807024 0,07273683 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,04807024 0,07267716 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,04807024 0,07261759 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,04807024 0,07255811 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,04807024 0,07249873 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,04807024 0,07243946 ! immunoglobulin production GO:0002377 13 13 0,000 0,04807024 0,07238027 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,04807024 0,07232119 ! negative regulation of intracellular transport GO:0032387 13 13 0,000 0,04807024 0,0722622 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,04807024 0,0722033 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,04807024 0,07214451 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,04807024 0,0720858 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,04807024 0,0720272 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,04807024 0,07196869 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,04807024 0,07191027 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,04807024 0,07185195 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,04807024 0,07179372 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,04807024 0,07173559 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,04807024 0,07167755 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,04807024 0,07161961 ! blastocyst development GO:0001824 13 13 0,000 0,04807024 0,07156176 ! telomere organization GO:0032200 13 13 0,000 0,04807024 0,071504 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,04807024 0,07144633 ! regulation of amine transport GO:0051952 13 13 0,000 0,04807024 0,07138876 ! tissue homeostasis GO:0001894 13 13 0,000 0,04807024 0,07133128 GO:0048871|multicellular organismal homeostasis, ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,04807024 0,0712739 ! regulation of response to stress GO:0080134 97 94 1,000 0,04854377 0,07191815 ! blood vessel development GO:0001568 95 94 1,000 0,04854377 0,07186038 ! pattern specification process GO:0007389 96 94 1,000 0,04854377 0,07180271 ! regulation of cell growth GO:0001558 97 96 1,000 0,05041167 0,07450579 ! vasculature development GO:0001944 97 96 1,000 0,05041167 0,07444609 ! neuron fate commitment GO:0048663 14 14 0,000 0,05167446 0,07624982 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,05167446 0,07618882 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,05167446 0,07612792 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,05167446 0,07606712 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,05167446 0,07600641 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,05167446 0,0759458 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,05167446 0,07588528 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,05167446 0,07582486 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,05167446 0,07576454 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,05167446 0,07570432 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,05167446 0,07564419 ! vesicle docking GO:0048278 14 14 0,000 0,05167446 0,07558415 ! superoxide metabolic process GO:0006801 15 14 0,000 0,05167446 0,07552421 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,05167446 0,07546437 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,05167446 0,07540462 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,05167446 0,07534496 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,05167446 0,0752854 ! hair cycle GO:0042633 14 14 0,000 0,05167446 0,07522593 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,05167446 0,07516656 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,05167446 0,07510728 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,05167446 0,07504809 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,05167446 0,074989 ! lysosome organization GO:0007040 14 14 0,000 0,05167446 0,07493 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,05167446 0,07487109 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,05167446 0,07481228 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,05167446 0,07475356 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,05167446 0,07469493 ! primary neural tube formation GO:0014020 15 14 0,000 0,05167446 0,07463639 ! peptide cross-linking GO:0018149 14 14 0,000 0,05167446 0,07457794 ! regulation of behavior GO:0050795 14 14 0,000 0,05167446 0,07451959 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,05167446 0,07446132 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,05167446 0,07440315 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,05167446 0,07434507 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,05167446 0,07428707 ! formation of primary germ layer GO:0001704 14 14 0,000 0,05167446 0,07422917 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,05167446 0,07417136 ! collagen fibril organization GO:0030199 14 14 0,000 0,05167446 0,07411364 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,05167446 0,07405601 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,05167446 0,07399847 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,05167446 0,07394102 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,05167446 0,07388365 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,05167446 0,07382638 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,05167446 0,07376919 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,05167446 0,0737121 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,05167446 0,07365509 ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 0,05230563 0,07449713 ! anti-apoptosis GO:0006916 100 99 1,000 0,05326224 0,07580101 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,05422519 0,0771119 ! hemopoiesis GO:0030097 104 100 1,000 0,05422519 0,07705245 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,05526556 0,07847028 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,05526556 0,07840987 ! positive regulation of ossification GO:0045778 15 15 0,000 0,05526556 0,07834955 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,05526556 0,07828933 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,05526556 0,0782292 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,05526556 0,07816916 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,05526556 0,07810922 ! response to vitamin GO:0033273 15 15 0,000 0,05526556 0,07804936 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,05526556 0,0779896 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,05526556 0,07792993 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,05526556 0,07787035 ! ovarian follicle development GO:0001541 15 15 0,000 0,05526556 0,07781086 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,05526556 0,07775147 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,05526556 0,07769216 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,05526556 0,07763294 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,05526556 0,07757382 ! heme metabolic process GO:0042168 15 15 0,000 0,05526556 0,07751478 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,05526556 0,07745583 ! chromosome condensation GO:0030261 15 15 0,000 0,05526556 0,07739698 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,05526556 0,07733821 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,05526556 0,07727953 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,05526556 0,07722094 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,05526556 0,07716244 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,05526556 0,07710403 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,05526556 0,0770457 ! phospholipid transport GO:0015914 15 15 0,000 0,05526556 0,07698747 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,05526556 0,07692932 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,05526556 0,07687126 ! glutathione metabolic process GO:0006749 16 15 0,000 0,05526556 0,07681329 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,05526556 0,0767554 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,05526556 0,07669761 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,05526556 0,07663989 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,05526556 0,07658227 ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,05526556 0,07652473 ! protein homooligomerization GO:0051260 15 15 0,000 0,05526556 0,07646728 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,05526556 0,07640992 ! alkaloid metabolic process GO:0009820 16 16 0,000 0,05884357 0,08129588 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,05884357 0,08123499 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,05884357 0,08117418 ! learning GO:0007612 16 16 0,000 0,05884357 0,08111347 ! circadian rhythm GO:0007623 16 16 0,000 0,05884357 0,08105285 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,05884357 0,08099231 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,05884357 0,08093187 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,05884357 0,08087152 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,05884357 0,08081126 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,05884357 0,08075109 ! vesicle targeting GO:0006903 17 16 0,000 0,05884357 0,080691 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,05884357 0,08063101 ! iron ion homeostasis GO:0055072 16 16 0,000 0,05884357 0,0805711 ! positive regulation of cell development GO:0010720 16 16 0,000 0,05884357 0,08051129 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,05884357 0,08045156 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,05884357 0,08039193 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,05884357 0,08033238 ! pentose metabolic process GO:0019321 16 16 0,000 0,05884357 0,08027291 ! fatty acid transport GO:0015908 16 16 0,000 0,05884357 0,08021354 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,05884357 0,08015426 ! cofactor catabolic process GO:0051187 16 16 0,000 0,05884357 0,08009506 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,05884357 0,08003595 ! polyol metabolic process GO:0019751 16 16 0,000 0,05884357 0,07997692 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,05884357 0,07991799 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,05884357 0,07985914 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,05884357 0,07980037 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,05884357 0,0797417 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,05884357 0,07968311 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,05884357 0,0796246 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,05884357 0,07956618 ! regulation of coagulation GO:0050818 17 16 0,000 0,05884357 0,07950785 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,06240856 0,08426299 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,06240856 0,0842013 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,06240856 0,08413971 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,06240856 0,0840782 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,06240856 0,08401678 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,06240856 0,08395546 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,06240856 0,08389422 ! sensory perception of smell GO:0007608 17 17 0,000 0,06240856 0,08383307 ! glucose transport GO:0015758 17 17 0,000 0,06240856 0,08377202 ! tissue remodeling GO:0048771 17 17 0,000 0,06240856 0,08371105 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,06240856 0,08365017 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,06240856 0,08358937 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,06240856 0,08352867 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,06240856 0,08346805 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,06240856 0,08340753 ! neural crest cell development GO:0014032 19 17 0,000 0,06240856 0,08334709 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,06240856 0,08328673 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,06240856 0,08322647 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,06240856 0,08316629 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,06240856 0,0831062 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,06240856 0,08304619 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,06240856 0,08298628 ! pigmentation GO:0043473 17 17 0,000 0,06240856 0,08292644 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,06240856 0,0828667 ! adult locomotory behavior GO:0008344 17 17 0,000 0,06240856 0,08280704 ! embryonic organ development GO:0048568 17 17 0,000 0,06240856 0,08274747 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,06240856 0,08268798 ! liver development GO:0001889 17 17 0,000 0,06240856 0,08262858 ! gene silencing GO:0016458 17 17 0,000 0,06240856 0,08256926 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,06596056 0,08720611 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,06596056 0,08714359 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,06596056 0,08708117 ! meiosis I GO:0007127 18 18 0,000 0,06596056 0,08701884 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,06596056 0,08695659 ! membrane docking GO:0022406 18 18 0,000 0,06596056 0,08689443 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,06596056 0,08683237 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,06596056 0,08677039 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,06596056 0,0867085 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,06596056 0,0866467 ! hexose transport GO:0008645 18 18 0,000 0,06596056 0,08658498 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,06596056 0,08652335 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,06596056 0,08646182 ! ceramide metabolic process GO:0006672 18 18 0,000 0,06596056 0,08640037 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,06596056 0,086339 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,06596056 0,08627772 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,06596056 0,08621653 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,06596056 0,08615543 ! BMP signaling pathway GO:0030509 18 18 0,000 0,06596056 0,08609441 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,06596056 0,08603348 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,06949962 0,09058543 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,06949962 0,09052141 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,06949962 0,09045749 ! feeding behavior GO:0007631 19 19 0,000 0,06949962 0,09039365 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,06949962 0,0903299 ! peroxisome organization GO:0007031 19 19 0,000 0,06949962 0,09026624 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,06949962 0,09020268 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,06949962 0,0901392 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,06949962 0,09007581 ! metanephros development GO:0001656 19 19 0,000 0,06949962 0,09001251 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,06949962 0,0899493 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,06949962 0,08988618 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,06949962 0,08982314 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,06949962 0,0897602 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,06949962 0,08969734 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,06949962 0,08963457 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,06949962 0,08957189 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,06949962 0,08950929 ! eye morphogenesis GO:0048592 19 19 0,000 0,06949962 0,08944679 ! regulation of cell shape GO:0008360 21 19 0,000 0,06949962 0,08938437 ! placenta development GO:0001890 19 19 0,000 0,06949962 0,08932204 ! response to heat GO:0009408 19 19 0,000 0,06949962 0,08925979 ! vesicle localization GO:0051648 20 19 0,000 0,06949962 0,08919763 ! regulation of muscle development GO:0048634 21 20 0,000 0,07302578 0,09365798 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,07302578 0,09359285 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,07302578 0,09352781 ! neural tube development GO:0021915 21 20 0,000 0,07302578 0,09346286 ! nucleus organization GO:0006997 20 20 0,000 0,07302578 0,093398 ! phagocytosis GO:0006909 21 20 0,000 0,07302578 0,09333323 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,07302578 0,09326855 ! protein targeting to membrane GO:0006612 22 20 0,000 0,07302578 0,09320396 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,07302578 0,09313946 ! chromatin remodeling GO:0006338 20 20 0,000 0,07302578 0,09307505 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,07302578 0,09301073 ! lipid oxidation GO:0034440 20 20 0,000 0,07302578 0,09294649 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,07302578 0,09288235 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,07302578 0,09281829 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,07302578 0,09275432 ! RNA modification GO:0009451 20 20 0,000 0,07302578 0,09269044 ! single fertilization GO:0007338 21 20 0,000 0,07302578 0,09262665 ! regulation of B cell activation GO:0050864 20 20 0,000 0,07302578 0,09256294 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,0765391 0,09694952 ! mRNA catabolic process GO:0006402 21 21 0,000 0,0765391 0,09688294 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,0765391 0,09681644 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,0765391 0,09675004 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,0765391 0,09668373 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,0765391 0,0966175 ! ear morphogenesis GO:0042471 21 21 0,000 0,0765391 0,09655137 ! organic anion transport GO:0015711 21 21 0,000 0,0765391 0,09648533 ! cholesterol transport GO:0030301 21 21 0,000 0,0765391 0,09641938 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,0765391 0,09635352 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,0765391 0,09628775 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,0765391 0,09622207 ! regulation of proteolysis GO:0030162 21 21 0,000 0,0765391 0,09615648 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,0765391 0,09609098 ! RNA export from nucleus GO:0006405 22 22 0,000 0,08003961 0,10041729 ! sister chromatid segregation GO:0000819 22 22 0,000 0,08003961 0,10034897 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,08003961 0,10028076 ! regulation of ion transport GO:0043269 22 22 0,000 0,08003961 0,10021263 ! odontogenesis GO:0042476 22 22 0,000 0,08003961 0,1001446 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,08003961 0,10007666 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! embryonic skeletal system development GO:0048706 22 22 0,000 0,08003961 0,10000881 ! ovulation cycle process GO:0022602 22 22 0,000 0,08003961 0,09994105 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,08003961 0,09987339 ! cell chemotaxis GO:0060326 23 22 0,000 0,08003961 0,09980581 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,08003961 0,09973833 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,08003961 0,09967094 ! male sex differentiation GO:0046661 22 22 0,000 0,08003961 0,09960364 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,08003961 0,09953643 ! biopolymer methylation GO:0043414 22 22 0,000 0,08003961 0,09946931 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,08003961 0,09940229 ! detection of external stimulus GO:0009581 23 22 0,000 0,08003961 0,09933535 ! neuron migration GO:0001764 22 22 0,000 0,08003961 0,0992685 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,08003961 0,09920174 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,08003961 0,09913508 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,08003961 0,0990685 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,08003961 0,09900201 ! aerobic respiration GO:0009060 22 22 0,000 0,08003961 0,09893561 ! cytokine production GO:0001816 22 22 0,000 0,08003961 0,0988693 ! cytokinesis GO:0000910 23 22 0,000 0,08003961 0,09880308 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,08003961 0,09873694 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,08352735 0,10297051 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,08352735 0,10290168 ! viral infectious cycle GO:0019058 23 23 0,000 0,08352735 0,10283294 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,08352735 0,10276429 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,08352735 0,10269574 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,08352735 0,10262727 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,08352735 0,1025589 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,08352735 0,10249062 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,08352735 0,10242243 ! female gonad development GO:0008585 23 23 0,000 0,08352735 0,10235433 ! lipid homeostasis GO:0055088 23 23 0,000 0,08352735 0,10228632 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,08352735 0,1022184 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,08352735 0,10215057 ! cell projection assembly GO:0030031 25 23 0,000 0,08352735 0,10208283 ! gliogenesis GO:0042063 24 24 0,000 0,08700238 0,10625937 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,08700238 0,106189 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,08700238 0,10611872 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,08700238 0,10604854 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,08700238 0,10597845 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,08700238 0,10590845 ! ovulation cycle GO:0042698 24 24 0,000 0,08700238 0,10583854 ! fertilization GO:0009566 25 24 0,000 0,08700238 0,10576873 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,08700238 0,10569901 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,08700238 0,10562938 ! glucan metabolic process GO:0044042 25 24 0,000 0,08700238 0,10555984 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,09046474 0,1096885 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,09046474 0,10961639 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,09046474 0,10954436 ! cellular component disassembly GO:0022411 26 25 0,000 0,09046474 0,10947244 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,09046474 0,10940061 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,09046474 0,10932887 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,09046474 0,10925722 ! excretion GO:0007588 25 25 0,000 0,09046474 0,10918567 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,09046474 0,10911422 ! gastrulation GO:0007369 25 25 0,000 0,09046474 0,10904285 ! regulation of endocytosis GO:0030100 25 25 0,000 0,09046474 0,10897158 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,09046474 0,10890041 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,09046474 0,10882932 ! glycolysis GO:0006096 26 26 0,000 0,09391448 0,11290566 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,09391448 0,11283206 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,09391448 0,11275855 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,09391448 0,11268514 ! cellular defense response GO:0006968 26 26 0,000 0,09391448 0,11261183 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,09391448 0,11253861 ! regulation of protein secretion GO:0050708 26 26 0,000 0,09391448 0,11246548 ! germ cell development GO:0007281 27 26 0,000 0,09391448 0,11239245 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,09391448 0,11231952 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,09391448 0,11224668 ! chloride transport GO:0006821 27 27 0,000 0,09735163 0,11627936 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,09735163 0,11620405 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,09735163 0,11612883 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,09735163 0,11605372 ! peptide metabolic process GO:0006518 29 27 0,000 0,09735163 0,1159787 ! inner ear development GO:0048839 27 27 0,000 0,09735163 0,11590378 ! defense response to bacterium GO:0042742 27 27 0,000 0,09735163 0,11582895 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,09735163 0,11575422 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,09735163 0,11567959 ! cell growth GO:0016049 27 27 0,000 0,09735163 0,11560506 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,10077624 0,11959472 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,10077624 0,11951776 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,10077624 0,1194409 ! carbohydrate transport GO:0008643 28 28 0,000 0,10077624 0,11936414 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,10077624 0,11928748 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,10077624 0,11921091 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,10077624 0,11913445 ! developmental growth GO:0048589 28 28 0,000 0,10077624 0,11905808 ! cartilage development GO:0051216 29 28 0,000 0,10077624 0,11898181 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,10418835 0,12293158 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,10418835 0,12285293 ! leukocyte migration GO:0050900 30 29 0,000 0,10418835 0,12277438 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,10418835 0,12269593 ! antigen processing and presentation GO:0019882 29 29 0,000 0,10418835 0,12261758 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,10418835 0,12253933 ! tRNA processing GO:0008033 29 29 0,000 0,10418835 0,12246118 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,10418835 0,12238313 ! adult behavior GO:0030534 30 29 0,000 0,10418835 0,12230518 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,10418835 0,12222733 ! transition metal ion transport GO:0000041 31 30 0,000 0,10758802 0,12613531 ! RNA catabolic process GO:0006401 30 30 0,000 0,10758802 0,12605513 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,10758802 0,12597504 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,10758802 0,12589506 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,10758802 0,12581517 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,10758802 0,12573539 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,10758802 0,12565571 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,10758802 0,12557613 ! response to temperature stimulus GO:0009266 30 30 0,000 0,10758802 0,12549666 ! regulation of ossification GO:0030278 30 30 0,000 0,10758802 0,12541728 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,10758802 0,125338 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,10758802 0,12525882 GO:0019724|B cell mediated immunity, ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,10758802 0,12517974 ! vesicle organization GO:0016050 30 30 0,000 0,10758802 0,12510077 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,10758802 0,12502189 ! establishment of organelle localization GO:0051656 31 30 0,000 0,10758802 0,12494311 ! regulation of translational initiation GO:0006446 31 31 0,000 0,11097527 0,12879561 ! membrane fusion GO:0006944 31 31 0,000 0,11097527 0,12871456 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,11097527 0,1286336 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,11097527 0,12855275 ! ion transmembrane transport GO:0034220 31 31 0,000 0,11097527 0,128472 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,11097527 0,12839136 ! digestion GO:0007586 31 31 0,000 0,11097527 0,12831081 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,11097527 0,12823036 ! regulation of heart contraction GO:0008016 31 31 0,000 0,11097527 0,12815002 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,11097527 0,12806977 ! camera-type eye development GO:0043010 31 31 0,000 0,11097527 0,12798963 ! extracellular matrix organization GO:0030198 31 31 0,000 0,11097527 0,12790959 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,11097527 0,12782964 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,11097527 0,1277498 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,11097527 0,12767006 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,11097527 0,12759041 ! cell redox homeostasis GO:0045454 32 32 0,000 0,11435017 0,13138863 ! glucose catabolic process GO:0006007 32 32 0,000 0,11435017 0,13130677 ! lipid modification GO:0030258 32 32 0,000 0,11435017 0,13122501 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,11435017 0,13114335 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,11435017 0,13106179 ! cell maturation GO:0048469 32 32 0,000 0,11435017 0,13098033 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,11435017 0,13089898 ! nuclear export GO:0051168 32 32 0,000 0,11435017 0,13081773 ! kidney development GO:0001822 32 32 0,000 0,11435017 0,13073657 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,11435017 0,13065552 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,11771274 0,13441424 ! amino acid transport GO:0006865 33 33 0,000 0,11771274 0,13433101 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,11771274 0,13424788 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,11771274 0,13416486 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,11771274 0,13408194 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,11771274 0,13399912 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,11771274 0,13391641 ! regulation of actin filament length GO:0030832 34 34 0,000 0,12106303 0,13764292 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,12106303 0,13755806 ! response to metal ion GO:0010038 34 34 0,000 0,12106303 0,1374733 ! ear development GO:0043583 34 34 0,000 0,12106303 0,13738865 ! muscle cell differentiation GO:0042692 35 34 0,000 0,12106303 0,13730411 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,12106303 0,13721966 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,12106303 0,13713532 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,12106303 0,13705109 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,12106303 0,13696696 ! secondary metabolic process GO:0019748 34 34 0,000 0,12106303 0,13688293 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,12106303 0,136799 ! detection of stimulus GO:0051606 36 34 0,000 0,12106303 0,13671518 ! acute inflammatory response GO:0002526 35 35 0,000 0,12440109 0,14039879 ! regulation of cellular component size GO:0032535 35 35 0,000 0,12440109 0,14031286 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,12440109 0,14022704 ! mesoderm development GO:0007498 35 35 0,000 0,12440109 0,14014133 ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,12440109 0,14005572 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,12440109 0,13997022 ! inorganic anion transport GO:0015698 35 35 0,000 0,12440109 0,13988482 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,12440109 0,13979952 ! regulation of immune effector process GO:0002697 35 35 0,000 0,12440109 0,13971433 ! hydrogen transport GO:0006818 36 36 0,000 0,12772696 0,14336224 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,12772696 0,14327498 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,12772696 0,14318783 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,12772696 0,14310079 ! regulation of mitosis GO:0007088 37 36 0,000 0,12772696 0,14301385 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,12772696 0,14292701 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,12772696 0,14284029 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,12772696 0,14275367 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,12772696 0,14266715 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,12772696 0,14258074 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,12772696 0,14249443 ! gonad development GO:0008406 36 36 0,000 0,12772696 0,14240822 ! activation of immune response GO:0002253 36 36 0,000 0,12772696 0,14232212 ! coagulation GO:0050817 39 36 0,000 0,12772696 0,14223613 GO:0007596|blood coagulation, ! meiosis GO:0007126 37 37 0,000 0,13104068 0,14583815 GO:0051327|M phase of meiotic cell cycle, ! eye development GO:0001654 37 37 0,000 0,13104068 0,14575014 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,13104068 0,14566223 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,13104068 0,14557443 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,13104068 0,14548673 ! adaptive immune response GO:0002250 37 37 0,000 0,13104068 0,14539914 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! neurotransmitter transport GO:0006836 40 38 0,000 0,1343423 0,14897284 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,1343423 0,14888326 ! exocytosis GO:0006887 40 38 0,000 0,1343423 0,14879378 ! chromosome segregation GO:0007059 38 38 0,000 0,1343423 0,14870442 ! urogenital system development GO:0001655 38 38 0,000 0,1343423 0,14861516 ! hexose catabolic process GO:0019320 38 38 0,000 0,1343423 0,14852601 ! RNA elongation GO:0006354 38 38 0,000 0,1343423 0,14843696 ! meiotic cell cycle GO:0051321 38 38 0,000 0,1343423 0,14834802 ! regulation of neurological system process GO:0031644 38 38 0,000 0,1343423 0,14825919 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,1343423 0,14817047 ! hemostasis GO:0007599 42 39 0,000 0,13763185 0,15170783 ! response to unfolded protein GO:0006986 39 39 0,000 0,13763185 0,15161715 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,13763185 0,15152658 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,13763185 0,15143612 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,13763185 0,15134576 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,13763185 0,15125551 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,13763185 0,15116537 ! developmental maturation GO:0021700 39 39 0,000 0,13763185 0,15107534 ! limb development GO:0060173 39 39 0,000 0,13763185 0,15098541 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! DNA catabolic process GO:0006308 41 40 0,000 0,14090938 0,15448898 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,14090938 0,15439713 ! organelle localization GO:0051640 41 40 0,000 0,14090938 0,15430539 ! amine catabolic process GO:0009310 42 41 0,000 0,14417492 0,15778764 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,14417492 0,157694 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,14417492 0,15760047 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,14417492 0,15750705 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,14417492 0,15741374 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,14742854 0,16087081 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,14742854 0,16077562 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,14742854 0,16068054 ! protein ubiquitination GO:0016567 43 42 0,000 0,14742854 0,16058557 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,14742854 0,16049072 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,14742854 0,16039598 ! forebrain development GO:0030900 43 42 0,000 0,14742854 0,16030135 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,14742854 0,16020684 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,14742854 0,16011243 ! reproductive structure development GO:0048608 43 43 0,000 0,15067025 0,16353668 ! alcohol catabolic process GO:0046164 43 43 0,000 0,15067025 0,16344042 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,15067025 0,16334428 ! humoral immune response GO:0006959 44 44 0,000 0,15390012 0,16674774 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,15390012 0,16664977 ! mRNA transport GO:0051028 44 44 0,000 0,15390012 0,16655192 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,15390012 0,16645417 ! vitamin metabolic process GO:0006766 44 44 0,000 0,15390012 0,16635655 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,15390012 0,16625904 ! amine biosynthetic process GO:0009309 46 45 0,000 0,15711817 0,16963608 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,15711817 0,16953676 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,15711817 0,16943756 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,15711817 0,16933847 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,15711817 0,1692395 ! protein processing GO:0016485 45 45 0,000 0,15711817 0,16914064 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,16032445 0,17249151 ! tube morphogenesis GO:0035239 47 46 0,000 0,16032445 0,17239087 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,16032445 0,17229035 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,16032445 0,17218995 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,16032445 0,17208967 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,163519 0,17541648 ! regulation of blood pressure GO:0008217 48 47 0,000 0,163519 0,17531444 ! sex differentiation GO:0007548 47 47 0,000 0,163519 0,17521251 ! amine transport GO:0015837 47 47 0,000 0,163519 0,1751107 ! rhythmic process GO:0048511 47 47 0,000 0,163519 0,17500901 ! calcium ion transport GO:0006816 48 48 0,000 0,16670186 0,17831197 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,16670186 0,17820855 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,16670186 0,17810524 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,16670186 0,17800205 ! DNA recombination GO:0006310 48 48 0,000 0,16670186 0,17789898 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,16987308 0,18117829 ! divalent metal ion transport GO:0070838 49 49 0,000 0,16987308 0,1810735 ! response to nutrient GO:0007584 49 49 0,000 0,16987308 0,18096884 ! response to bacterium GO:0009617 50 49 0,000 0,16987308 0,18086429 ! regulation of ligase activity GO:0051340 50 49 0,000 0,16987308 0,18075986 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,16987308 0,18065556 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,16987308 0,18055138 GO:0002696|positive regulation of leukocyte activation, ! chromatin assembly GO:0031497 50 50 0,000 0,17303269 0,1838036 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,17303269 0,18369772 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,17303269 0,18359197 ! transcription initiation GO:0006352 50 50 0,000 0,17303269 0,18348633 ! anatomical structure homeostasis GO:0060249 51 50 0,000 0,17303269 0,18338082 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,17618074 0,18660982 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,17618074 0,18650264 ! positive regulation of immune response GO:0050778 51 51 0,000 0,17618074 0,18639558 ! rRNA metabolic process GO:0016072 51 51 0,000 0,17618074 0,18628864 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,17618074 0,18618182 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,17618074 0,18607513 ! protein maturation GO:0051604 51 51 0,000 0,17618074 0,18596855 ! RNA localization GO:0006403 52 52 0,000 0,17931726 0,18917098 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,17931726 0,18906276 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,17931726 0,18895466 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,17931726 0,18884669 ! sodium ion transport GO:0006814 53 53 0,000 0,18244229 0,19202807 ! tRNA metabolic process GO:0006399 53 53 0,000 0,18244229 0,19191846 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,18244229 0,19180898 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,18244229 0,19169963 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,18244229 0,1915904 ! response to virus GO:0009615 54 54 0,000 0,18555589 0,19474914 ! sulfur metabolic process GO:0006790 55 54 0,000 0,18555589 0,1946383 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,18555589 0,19452759 ! nucleosome organization GO:0034728 55 55 0,000 0,18865808 0,19766733 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,18865808 0,19755502 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,18865808 0,19744284 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,1917489 0,20056369 ! ATP metabolic process GO:0046034 57 57 0,000 0,1948284 0,20366917 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,1948284 0,20355371 ! carboxylic acid transport GO:0046942 59 59 0,000 0,2009536 0,20983427 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,2009536 0,20971545 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,2009536 0,20959677 ! potassium ion transport GO:0006813 60 60 0,000 0,20399937 0,21265319 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,20399937 0,21253298 ! cellular respiration GO:0045333 62 61 0,000 0,20703398 0,21557267 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,20703398 0,21545094 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,20703398 0,21532936 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,21005746 0,21835076 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,21005746 0,21822768 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,21005746 0,21810473 GO:0060429|epithelium development, ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,21005746 0,21798192 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,21005746 0,21785926 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,21306985 0,22085925 ! glucose metabolic process GO:0006006 63 63 0,000 0,21306985 0,2207351 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,21306985 0,22061109 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,21306985 0,22048722 ! angiogenesis GO:0001525 65 64 0,000 0,2160712 0,22346758 ! anion transport GO:0006820 65 65 0,000 0,21906154 0,22643321 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,21906154 0,22630629 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,22204091 0,22925568 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,22204091 0,22912732 ! DNA packaging GO:0006323 66 66 0,000 0,22204091 0,2289991 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,22204091 0,22887103 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,22500935 0,23180113 ! muscle contraction GO:0006936 67 67 0,000 0,22500935 0,23167163 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,22500935 0,23154228 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,22796689 0,23445479 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,22796689 0,23432403 ! regulation of translation GO:0006417 69 69 0,000 0,23091358 0,23722059 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,23384946 0,24010281 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,23677456 0,24297077 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,23677456 0,24283556 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,23677456 0,2427005 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,23677456 0,2425656 ! negative regulation of signal transduction GO:0009968 71 71 0,000 0,23677456 0,24243084 ! secretion by cell GO:0032940 75 72 0,000 0,23968891 0,24527855 ! muscle system process GO:0003012 72 72 0,000 0,23968891 0,24514243 ! sensory organ development GO:0007423 72 72 0,000 0,23968891 0,24500647 ! regulation of cytokine production GO:0001817 72 72 0,000 0,23968891 0,24487066 ! electron transport chain GO:0022900 75 74 0,000 0,24548556 0,25065368 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,24548556 0,25051489 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,24836793 0,25331604 ! response to oxidative stress GO:0006979 76 75 0,000 0,24836793 0,25317593 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,24836793 0,25303598 ! negative regulation of cell communication GO:0010648 76 76 0,000 0,2512397 0,25582031 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,2512397 0,25567906 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,25410093 0,25844813 ! metal ion homeostasis GO:0055065 78 78 0,000 0,25695163 0,26120345 ! regulation of immune response GO:0050776 78 78 0,000 0,25695163 0,26105946 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,26262166 0,26667312 ! lipid catabolic process GO:0016042 82 81 0,000 0,26544105 0,26938758 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,27104876 0,27492728 ! ncRNA processing GO:0034470 83 83 0,000 0,27104876 0,27477605 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,27383715 0,27745018 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,27661529 0,28011098 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,27661529 0,27995716 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,27938321 0,28260332 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,27938321 0,2824483 ! male gamete generation GO:0048232 90 88 0,000 0,28488853 0,28785612 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,28488853 0,28769839 ! chemotaxis GO:0006935 90 89 0,000 0,287626 0,29030379 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,287626 0,29014489 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,29035339 0,29273594 ! brain development GO:0007420 91 90 0,000 0,29035339 0,29257589 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,29307074 0,29515266 ! DNA replication GO:0006260 91 91 0,000 0,29307074 0,29499147 ! visual perception GO:0007601 93 92 0,000 0,29577809 0,29755405 GO:0050953|sensory perception of light stimulus, ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,29577809 0,29739171 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,29577809 0,29722956 ! tissue morphogenesis GO:0048729 94 93 0,000 0,29847546 0,29977671 ! epidermis development GO:0008544 94 94 0,000 0,3011629 0,30231112 ! cofactor metabolic process GO:0051186 95 94 0,000 0,3011629 0,30214655 ! endocytosis GO:0006897 99 98 0,000 0,31181399 0,31266223 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,31181399 0,31249221 ! blood circulation GO:0008015 99 98 0,000 0,31181399 0,31232238 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,31181399 0,31215273 ! ectoderm development GO:0007398 99 99 0,000 0,31445227 0,31462298 ! response to other organism GO:0051707 101 100 0,000 0,31708083 0,31708083