pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6495-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of protein export from nucleus GO:0046825 10 7 3,000 2,477E-09 5,959E-06 ! organ growth GO:0035265 15 7 3,000 2,477E-09 2,979E-06 ! negative regulation of peptide secretion GO:0002792 10 7 3,000 2,477E-09 1,986E-06 GO:0046676|negative regulation of insulin secretion, ! cellular response to hormone stimulus GO:0032870 167 82 6,000 4,916E-09 2,957E-06 ! regulation of growth hormone secretion GO:0060123 16 8 3,000 4,942E-09 2,378E-06 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 3,000 8,875E-09 3,559E-06 ! positive regulation of MAP kinase activity GO:0043406 160 93 6,000 1,193E-08 4,101E-06 ! regulation of DNA replication GO:0006275 101 56 5,000 1,618E-08 4,867E-06 ! DNA damage response, signal transduction GO:0042770 128 60 5,000 2,472E-08 6,608E-06 ! DNA damage checkpoint GO:0000077 71 33 4,000 4,472E-08 1,076E-05 ! DNA integrity checkpoint GO:0031570 75 36 4,000 7,054E-08 1,543E-05 ! carbohydrate homeostasis GO:0033500 53 38 4,000 9,348E-08 1,874E-05 GO:0042593|glucose homeostasis, ! regulation of intracellular protein transport GO:0033157 80 42 4,000 1,57E-07 2,905E-05 ! negative regulation of hormone secretion GO:0046888 25 17 3,000 1,646E-07 2,83E-05 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 4,000 2,506E-07 4,019E-05 ! positive regulation of hormone secretion GO:0046887 32 19 3,000 2,669E-07 4,014E-05 ! regulation of DNA metabolic process GO:0051052 178 97 5,000 4,471E-07 6,327E-05 ! response to UV GO:0009411 104 53 4,000 5,161E-07 6,899E-05 ! regulation of intracellular transport GO:0032386 101 57 4,000 7,461E-07 9,448E-05 ! regulation of insulin secretion GO:0050796 37 25 3,000 8,594E-07 1,034E-04 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 1,013E-06 1,161E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,382E-06 1,511E-04 ! regulation of peptide secretion GO:0002791 47 29 3,000 1,599E-06 1,673E-04 ! activation of MAPK activity GO:0000187 115 67 4,000 1,681E-06 1,686E-04 ! cell cycle checkpoint GO:0000075 137 69 4,000 1,948E-06 1,874E-04 ! triglyceride metabolic process GO:0006641 43 31 3,000 2,109E-06 1,952E-04 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 2,000 2,949E-06 2,628E-04 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 2,000 2,949E-06 2,534E-04 ! negative regulation of secretion GO:0051048 63 35 3,000 3,478E-06 2,886E-04 ! neutral lipid metabolic process GO:0006638 50 35 3,000 3,478E-06 2,789E-04 GO:0006639|acylglycerol metabolic process, ! glycerol ether metabolic process GO:0006662 53 37 3,000 4,367E-06 3,39E-04 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 4,367E-06 3,284E-04 ! negative regulation of transport GO:0051051 153 84 4,000 5,167E-06 3,767E-04 ! organic ether metabolic process GO:0018904 55 39 3,000 5,414E-06 3,831E-04 ! regulation of hormone secretion GO:0046883 62 40 3,000 6,002E-06 4,126E-04 ! regulation of protein transport GO:0051223 154 87 4,000 6,141E-06 4,104E-04 GO:0070201|regulation of establishment of protein localization, ! hormone-mediated signaling GO:0009755 74 41 3,000 6,636E-06 4,315E-04 ! response to X-ray GO:0010165 25 13 2,000 6,983E-06 4,422E-04 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 8,051E-06 4,967E-04 ! response to gamma radiation GO:0010332 28 14 2,000 8,869E-06 5,335E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 9,676E-06 5,678E-04 ! regulation of protein localization GO:0032880 176 97 4,000 1,047E-05 5,995E-04 ! response to insulin stimulus GO:0032868 95 46 3,000 1,057E-05 5,916E-04 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 1,106E-05 6,049E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,646E-05 8,802E-04 ! regulation of multicellular organism growth GO:0040014 85 55 3,000 2,166E-05 1,133E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 2,742E-05 1,404E-03 ! positive regulation of secretion GO:0051047 95 59 3,000 2,864E-05 1,436E-03 ! integrin-mediated signaling pathway GO:0007229 135 59 3,000 2,864E-05 1,406E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 3,062E-05 1,473E-03 ! cell aging GO:0007569 44 21 2,000 3,192E-05 1,506E-03 ! response to peptide hormone stimulus GO:0043434 122 61 3,000 3,269E-05 1,513E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 3,688E-05 1,674E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 2,000 3,688E-05 1,643E-03 ! multicellular organism reproduction GO:0032504 111 64 3,000 3,953E-05 1,729E-03 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of DNA replication GO:0045740 43 23 2,000 4,233E-05 1,819E-03 ! protein tetramerization GO:0051262 52 24 2,000 4,827E-05 2,038E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 5,474E-05 2,271E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 5,474E-05 2,232E-03 ! negative regulation of DNA replication GO:0008156 42 25 2,000 5,474E-05 2,195E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 2,000 5,474E-05 2,159E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 6,174E-05 2,396E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 6,931E-05 2,647E-03 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 7,746E-05 2,912E-03 ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 8,585E-05 3,178E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 8,585E-05 3,13E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 8,585E-05 3,083E-03 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 1,000 8,585E-05 3,038E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 8,585E-05 2,994E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 8,585E-05 2,951E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 8,585E-05 2,909E-03 ! inner cell mass cell proliferation GO:0001833 5 5 1,000 8,585E-05 2,869E-03 ! regulation of sensory perception GO:0051931 7 5 1,000 8,585E-05 2,83E-03 GO:0051930|regulation of sensory perception of pain, ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 8,622E-05 2,803E-03 ! cell junction assembly GO:0034329 78 30 2,000 9,559E-05 3,067E-03 ! response to ionizing radiation GO:0010212 65 32 2,000 1,163E-04 3,681E-03 ! male meiosis GO:0007140 7 6 1,000 1,285E-04 4,016E-03 ! activation of MAPKKK activity GO:0000185 12 6 1,000 1,285E-04 3,965E-03 ! male sex determination GO:0030238 15 6 1,000 1,285E-04 3,914E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 1,000 1,285E-04 3,866E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! response to UV-C GO:0010225 11 6 1,000 1,285E-04 3,818E-03 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 1,285E-04 3,771E-03 ! cytoplasmic microtubule organization GO:0031122 14 6 1,000 1,285E-04 3,726E-03 ! regulation of DNA binding GO:0051101 155 88 3,000 1,375E-04 3,937E-03 ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 1,525E-04 4,316E-03 ! cell junction organization GO:0034330 86 36 2,000 1,66E-04 4,643E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 1,66E-04 4,59E-03 ! regulation of helicase activity GO:0051095 15 7 1,000 1,796E-04 4,91E-03 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 1,796E-04 4,855E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,796E-04 4,801E-03 ! positive regulation of mitotic cell cycle GO:0045931 12 7 1,000 1,796E-04 4,748E-03 ! wound healing, spreading of epidermal cells GO:0035313 14 7 1,000 1,796E-04 4,697E-03 ! centrosome duplication GO:0051298 13 7 1,000 1,796E-04 4,646E-03 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 1,796E-04 4,597E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 1,796E-04 4,549E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 1,796E-04 4,501E-03 ! response to tumor cell GO:0002347 13 7 1,000 1,796E-04 4,455E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 1,796E-04 4,409E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 1,847E-04 4,49E-03 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 1,953E-04 4,698E-03 ! hormone metabolic process GO:0042445 157 97 3,000 2,002E-04 4,768E-03 ! interphase GO:0051325 213 98 3,000 2,082E-04 4,911E-03 ! mammary gland development GO:0030879 86 39 2,000 2,111E-04 4,931E-03 ! cell cycle arrest GO:0007050 213 100 3,000 2,25E-04 5,206E-03 ! mesenchymal cell development GO:0014031 87 40 2,000 2,277E-04 5,218E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,39E-04 5,425E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 2,39E-04 5,374E-03 ! ER overload response GO:0006983 12 8 1,000 2,39E-04 5,324E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 2,39E-04 5,276E-03 ! blastocyst growth GO:0001832 19 8 1,000 2,39E-04 5,228E-03 ! double-strand break repair GO:0006302 81 44 2,000 3,026E-04 6,56E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 3,067E-04 6,589E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 3,067E-04 6,53E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 3,067E-04 6,473E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 3,067E-04 6,417E-03 ! receptor clustering GO:0043113 18 9 1,000 3,067E-04 6,361E-03 ! motor axon guidance GO:0008045 16 9 1,000 3,067E-04 6,307E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 3,067E-04 6,253E-03 ! induction of an organ GO:0001759 14 9 1,000 3,067E-04 6,201E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 3,454E-04 6,925E-03 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 3,454E-04 6,868E-03 ! positive regulation of DNA binding GO:0043388 73 47 2,000 3,682E-04 7,261E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 3,826E-04 7,485E-03 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 3,826E-04 7,424E-03 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 1,000 3,826E-04 7,365E-03 ! positive regulation of survival gene product expression GO:0045885 23 10 1,000 3,826E-04 7,306E-03 ! multicellular organism growth GO:0035264 18 10 1,000 3,826E-04 7,249E-03 ! midbrain development GO:0030901 13 10 1,000 3,826E-04 7,192E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 3,826E-04 7,137E-03 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 1,000 3,826E-04 7,082E-03 ! localization within membrane GO:0051668 20 10 1,000 3,826E-04 7,028E-03 ! positive regulation of cell cycle GO:0045787 89 48 2,000 3,919E-04 7,143E-03 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 3,919E-04 7,089E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 4,668E-04 8,381E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 4,668E-04 8,319E-03 ! regulation of intracellular pH GO:0051453 19 11 1,000 4,668E-04 8,258E-03 ! negative regulation of ossification GO:0030279 26 11 1,000 4,668E-04 8,197E-03 ! oocyte differentiation GO:0009994 18 11 1,000 4,668E-04 8,138E-03 ! developmental induction GO:0031128 19 11 1,000 4,668E-04 8,079E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of embryonic development GO:0045995 27 11 1,000 4,668E-04 8,022E-03 ! positive regulation of binding GO:0051099 78 51 2,000 4,688E-04 8E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 4,688E-04 7,944E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 5,59E-04 9,406E-03 ! virus-host interaction GO:0019048 29 12 1,000 5,59E-04 9,341E-03 ! regulation of B cell proliferation GO:0030888 20 12 1,000 5,59E-04 9,276E-03 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 5,59E-04 9,213E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 5,59E-04 9,15E-03 ! histone acetylation GO:0016573 26 12 1,000 5,59E-04 9,088E-03 ! peptidyl-lysine modification GO:0018205 21 12 1,000 5,59E-04 9,027E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 5,59E-04 8,967E-03 GO:0042130|negative regulation of T cell proliferation, ! aging GO:0007568 103 55 2,000 5,856E-04 9,331E-03 ! nucleotide-excision repair GO:0006289 83 56 2,000 6,174E-04 9,773E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 6,504E-04 0,01022708 ! positive regulation of cell migration GO:0030335 126 57 2,000 6,504E-04 0,01016067 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 6,594E-04 0,01023582 GO:0000725|recombinational repair, ! endocrine pancreas development GO:0031018 22 13 1,000 6,594E-04 0,0101702 ! cell-cell junction assembly GO:0007043 27 13 1,000 6,594E-04 0,01010543 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 6,594E-04 0,01004147 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 6,594E-04 9,978E-03 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 6,594E-04 9,916E-03 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 6,594E-04 9,854E-03 ! cytokine-mediated signaling pathway GO:0019221 97 59 2,000 7,195E-04 0,0106858 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 7,678E-04 0,01133387 ! regulation of S phase GO:0033261 23 14 1,000 7,678E-04 0,01126476 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 7,678E-04 0,01119649 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 7,678E-04 0,01112904 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 8,714E-04 0,0125549 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 8,843E-04 0,01266396 ! heterophilic cell adhesion GO:0007157 39 15 1,000 8,843E-04 0,01258902 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 8,843E-04 0,01251497 ! G1/S transition checkpoint GO:0031575 40 15 1,000 8,843E-04 0,01244178 ! intermediate filament cytoskeleton organization GO:0045104 31 15 1,000 8,843E-04 0,01236945 ! positive regulation of cell motion GO:0051272 146 64 2,000 9,123E-04 0,01268847 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 1,009E-03 0,01394718 ! G1 phase of mitotic cell cycle GO:0000080 35 16 1,000 1,009E-03 0,01386749 ! startle response GO:0001964 28 16 1,000 1,009E-03 0,01378869 ! activation of MAPKK activity GO:0000186 35 16 1,000 1,009E-03 0,01371079 ! intermediate filament-based process GO:0045103 32 16 1,000 1,009E-03 0,01363376 ! axon cargo transport GO:0008088 43 16 1,000 1,009E-03 0,0135576 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 1,009E-03 0,01348228 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 1,009E-03 0,01340779 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 1,009E-03 0,01333412 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 1,009E-03 0,01326126 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 1,042E-03 0,01362964 ! negative regulation of cell growth GO:0030308 132 67 2,000 1,042E-03 0,01355597 ! lung development GO:0030324 144 67 2,000 1,042E-03 0,01348309 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 2,000 1,042E-03 0,01341099 ! negative regulation of kinase activity GO:0033673 131 68 2,000 1,088E-03 0,01392567 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 1,088E-03 0,01385199 ! negative regulation of cell size GO:0045792 134 69 2,000 1,135E-03 0,01437479 ! signal complex assembly GO:0007172 41 17 1,000 1,141E-03 0,01437227 ! regulation of survival gene product expression GO:0045884 33 17 1,000 1,141E-03 0,01429741 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 1,141E-03 0,01422334 ! respiratory tube development GO:0030323 150 70 2,000 1,183E-03 0,01467752 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,281E-03 0,01580673 ! memory GO:0007613 31 18 1,000 1,281E-03 0,01572609 ! centrosome cycle GO:0007098 25 18 1,000 1,281E-03 0,01564626 ! cell-substrate junction assembly GO:0007044 54 18 1,000 1,281E-03 0,01556724 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 1,281E-03 0,01548901 ! negative regulation of transferase activity GO:0051348 140 72 2,000 1,284E-03 0,01544578 ! respiratory system development GO:0060541 153 72 2,000 1,284E-03 0,01536894 ! regulation of transcription factor activity GO:0051090 126 74 2,000 1,39E-03 0,01655159 GO:0090046|regulation of transcription regulator activity, ! lipid phosphorylation GO:0046834 35 19 1,000 1,429E-03 0,01693757 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 1,429E-03 0,01685454 ! neuromuscular junction development GO:0007528 34 19 1,000 1,429E-03 0,01677232 ! prostaglandin metabolic process GO:0006693 37 19 1,000 1,429E-03 0,01669091 GO:0006692|prostanoid metabolic process, ! G1 phase GO:0051318 40 19 1,000 1,429E-03 0,01661027 ! cell-cell junction organization GO:0045216 35 19 1,000 1,429E-03 0,01653042 ! regulation of catabolic process GO:0009894 161 76 2,000 1,501E-03 0,017275 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 1,585E-03 0,0181573 ! protein amino acid acetylation GO:0006473 39 20 1,000 1,585E-03 0,01807124 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 1,585E-03 0,017986 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 1,585E-03 0,01790156 GO:0010675|regulation of cellular carbohydrate metabolic process, ! pancreas development GO:0031016 35 20 1,000 1,585E-03 0,01781791 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 1,585E-03 0,01773503 ! cellular response to starvation GO:0009267 33 20 1,000 1,585E-03 0,01765293 ! negative regulation of T cell activation GO:0050868 40 20 1,000 1,585E-03 0,01757158 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 1,585E-03 0,01749097 ! protein oligomerization GO:0051259 139 78 2,000 1,617E-03 0,01776505 ! positive regulation of phosphorylation GO:0042327 129 79 2,000 1,677E-03 0,01834335 ! oogenesis GO:0048477 36 21 1,000 1,748E-03 0,01903312 ! positive regulation of inflammatory response GO:0050729 35 21 1,000 1,748E-03 0,01894738 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 2,000 1,802E-03 0,01944199 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 1,919E-03 0,02061641 ! microtubule-based transport GO:0010970 54 22 1,000 1,919E-03 0,02052478 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 1,919E-03 0,02043397 ! positive regulation of B cell activation GO:0050871 38 22 1,000 1,919E-03 0,02034395 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 1,919E-03 0,02025472 ! protein stabilization GO:0050821 39 22 1,000 1,919E-03 0,02016627 ! negative regulation of growth GO:0045926 155 84 2,000 2E-03 0,02091798 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 2,098E-03 0,02185366 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 2,098E-03 0,02175946 ! leukocyte adhesion GO:0007159 50 23 1,000 2,098E-03 0,02166607 ! sex determination GO:0007530 47 23 1,000 2,098E-03 0,02157348 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 2,098E-03 0,02148168 ! regulation of bone mineralization GO:0030500 49 23 1,000 2,098E-03 0,02139065 ! negative regulation of catabolic process GO:0009895 50 23 1,000 2,098E-03 0,0213004 ! gland development GO:0048732 206 88 2,000 2,283E-03 0,02308405 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 2,285E-03 0,02299817 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 2,285E-03 0,02290235 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 2,285E-03 0,02280732 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 2,285E-03 0,02271307 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 2,285E-03 0,0226196 ! myelination GO:0042552 45 25 1,000 2,478E-03 0,02443883 ! vasculogenesis GO:0001570 46 25 1,000 2,478E-03 0,02433908 ! receptor metabolic process GO:0043112 46 25 1,000 2,478E-03 0,02424014 ! response to starvation GO:0042594 42 25 1,000 2,478E-03 0,024142 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 2,478E-03 0,02404465 ! negative regulation of cell development GO:0010721 73 25 1,000 2,478E-03 0,02394809 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 2,478E-03 0,02385229 ! regulation of biomineral formation GO:0070167 51 25 1,000 2,478E-03 0,02375727 ! somitogenesis GO:0001756 43 25 1,000 2,478E-03 0,02366299 ! cellular response to nutrient levels GO:0031669 41 25 1,000 2,478E-03 0,02356946 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 2,68E-03 0,02538432 ! microtubule organizing center organization GO:0031023 39 26 1,000 2,68E-03 0,02528477 GO:0051297|centrosome organization, ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 2,68E-03 0,025186 GO:0045936|negative regulation of phosphate metabolic process, ! blastocyst development GO:0001824 49 26 1,000 2,68E-03 0,025088 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 2,889E-03 0,02693832 ! protein amino acid acylation GO:0043543 55 27 1,000 2,889E-03 0,02683431 ! mitochondrial membrane organization GO:0007006 57 27 1,000 2,889E-03 0,0267311 ! base-excision repair GO:0006284 41 27 1,000 2,889E-03 0,02662868 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 2,889E-03 0,02652704 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 3,105E-03 0,02840445 ! skeletal muscle tissue development GO:0007519 186 99 2,000 3,189E-03 0,02905933 GO:0060538|skeletal muscle organ development, ! regulation of pH GO:0006885 43 29 1,000 3,328E-03 0,03022025 ! response to organic cyclic substance GO:0014070 55 29 1,000 3,328E-03 0,03010664 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 3,328E-03 0,02999388 ! ensheathment of neurons GO:0007272 57 30 1,000 3,559E-03 0,03195509 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 3,559E-03 0,0318363 ! regulation of B cell activation GO:0050864 50 30 1,000 3,559E-03 0,03171838 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 3,798E-03 0,03371608 GO:0043433|negative regulation of transcription factor activity, ! regulation of protein import into nucleus GO:0042306 63 32 1,000 4,043E-03 0,03576303 ! peripheral nervous system development GO:0007422 64 32 1,000 4,043E-03 0,03563203 ! BMP signaling pathway GO:0030509 64 32 1,000 4,043E-03 0,03550198 ! hindbrain development GO:0030902 61 32 1,000 4,043E-03 0,03537288 ! positive regulation of catabolic process GO:0009896 64 32 1,000 4,043E-03 0,03524472 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 4,296E-03 0,0373116 ! cell fate specification GO:0001708 52 33 1,000 4,296E-03 0,03717739 ! adult locomotory behavior GO:0008344 59 33 1,000 4,296E-03 0,03704413 ! negative regulation of protein transport GO:0051224 69 33 1,000 4,296E-03 0,03691183 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 1,000 4,555E-03 0,0390045 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 4,555E-03 0,03886619 ! female gonad development GO:0008585 58 35 1,000 4,822E-03 0,04099749 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 4,822E-03 0,04085314 ! calcium-mediated signaling GO:0019722 62 35 1,000 4,822E-03 0,04070979 ! regulation of microtubule-based process GO:0032886 78 35 1,000 4,822E-03 0,04056745 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 5,096E-03 0,04272226 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 1,000 5,096E-03 0,04257392 ! maintenance of protein location in cell GO:0032507 86 36 1,000 5,096E-03 0,04242661 ! negative regulation of cell activation GO:0050866 65 36 1,000 5,096E-03 0,04228031 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 5,377E-03 0,04445758 ! negative regulation of DNA binding GO:0043392 68 37 1,000 5,377E-03 0,04430533 ! regulation of protein stability GO:0031647 73 37 1,000 5,377E-03 0,04415411 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 5,665E-03 0,04635982 ! development of primary female sexual characteristics GO:0046545 67 38 1,000 5,665E-03 0,04620267 GO:0046660|female sex differentiation, ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 5,665E-03 0,04604658 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! segmentation GO:0035282 67 39 1,000 5,96E-03 0,04827973 ! regulation of action potential in neuron GO:0019228 73 39 1,000 5,96E-03 0,04811772 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 1,000 6,261E-03 0,05038439 ! negative regulation of binding GO:0051100 72 40 1,000 6,261E-03 0,05021645 ! maintenance of protein location GO:0045185 91 40 1,000 6,261E-03 0,05004961 ! cytokinesis GO:0000910 72 40 1,000 6,261E-03 0,04988389 ! regulation of T cell proliferation GO:0042129 71 41 1,000 6,57E-03 0,05216913 ! T cell differentiation GO:0030217 81 41 1,000 6,57E-03 0,05199752 ! regulation of T cell differentiation GO:0045580 70 41 1,000 6,57E-03 0,05182703 ! female gamete generation GO:0007292 61 41 1,000 6,57E-03 0,05165767 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 6,885E-03 0,05396063 GO:0090047|positive regulation of transcription regulator activity, ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 6,885E-03 0,05378544 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 7,207E-03 0,05611922 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 7,207E-03 0,05593819 ! B cell differentiation GO:0030183 107 44 1,000 7,536E-03 0,05830199 ! developmental growth GO:0048589 82 44 1,000 7,536E-03 0,05811512 ! maintenance of location in cell GO:0051651 97 44 1,000 7,536E-03 0,05792945 ! regulation of JAK-STAT cascade GO:0046425 70 45 1,000 7,872E-03 0,06031546 ! icosanoid metabolic process GO:0006690 80 45 1,000 7,872E-03 0,06012398 ! cell growth GO:0016049 84 45 1,000 7,872E-03 0,05993372 ! positive regulation of protein transport GO:0051222 72 46 1,000 8,214E-03 0,06234115 ! positive regulation of defense response GO:0031349 76 47 1,000 8,562E-03 0,06478331 ! endosome transport GO:0016197 108 47 1,000 8,562E-03 0,06458023 ! mitochondrial transport GO:0006839 82 48 1,000 8,918E-03 0,06704937 ! Notch signaling pathway GO:0007219 96 48 1,000 8,918E-03 0,0668405 ! activation of caspase activity GO:0006919 84 48 1,000 8,918E-03 0,06663292 ! regulation of inflammatory response GO:0050727 75 48 1,000 8,918E-03 0,06642662 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 8,918E-03 0,0662216 ! regulation of action potential GO:0001508 95 49 1,000 9,279E-03 0,06869589 ! unsaturated fatty acid metabolic process GO:0033559 86 49 1,000 9,279E-03 0,06848517 ! endocrine system development GO:0035270 104 49 1,000 9,279E-03 0,06827573 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 9,279E-03 0,06806758 ! neuromuscular process GO:0050905 99 50 1,000 9,648E-03 0,07055347 ! histone modification GO:0016570 91 50 1,000 9,648E-03 0,07033967 ! negative regulation of immune system process GO:0002683 95 50 1,000 9,648E-03 0,07012717 ! regulation of ossification GO:0030278 117 50 1,000 9,648E-03 0,06991594 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,01002223 0,07241286 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 1,000 0,01002223 0,07219606 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,01040326 0,07471714 ! positive regulation of growth GO:0045927 90 52 1,000 0,01040326 0,07449477 ! covalent chromatin modification GO:0016569 101 52 1,000 0,01040326 0,07427372 ! synapse organization GO:0050808 85 52 1,000 0,01040326 0,07405397 ! cell maturation GO:0048469 100 53 1,000 0,01079064 0,07658488 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,01079064 0,07635963 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,01118432 0,07891342 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,01158427 0,08149638 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,01158427 0,08125878 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,01158427 0,08102256 ! heart morphogenesis GO:0003007 97 55 1,000 0,01158427 0,08078771 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,01199045 0,08337869 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,01240282 0,08599765 ! muscle fiber development GO:0048747 112 57 1,000 0,01240282 0,08575053 ! lipid modification GO:0030258 97 57 1,000 0,01240282 0,08550482 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,01240282 0,08526053 ! maintenance of location GO:0051235 118 57 1,000 0,01240282 0,08501762 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,01282134 0,08763674 ! adult behavior GO:0030534 99 58 1,000 0,01282134 0,08738848 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,01282134 0,08714162 ! viral reproductive process GO:0022415 126 62 1,000 0,01455611 0,09865353 ! gonad development GO:0008406 98 62 1,000 0,01455611 0,09837641 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01468961 0,09900054 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01468961 0,09872401 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01468961 0,09844901 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01468961 0,09817554 ! neuron fate determination GO:0048664 7 5 0,000 0,01468961 0,09790359 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01468961 0,09763313 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01468961 0,09736417 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01468961 0,09709669 ! polyol transport GO:0015791 12 5 0,000 0,01468961 0,09683067 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01468961 0,0965661 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01468961 0,09630298 ! response to superoxide GO:0000303 10 5 0,000 0,01468961 0,09604129 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01468961 0,09578101 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01468961 0,09552215 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01468961 0,09526467 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01468961 0,09500859 ! female meiosis GO:0007143 7 5 0,000 0,01468961 0,09475387 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01468961 0,09450052 ! cobalt ion transport GO:0006824 11 5 0,000 0,01468961 0,09424852 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01468961 0,09399786 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01468961 0,09374853 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01468961 0,09350051 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01468961 0,09325381 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01468961 0,09300841 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01468961 0,09276429 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01468961 0,09252145 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01468961 0,09227988 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01468961 0,09203957 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01468961 0,0918005 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01468961 0,09156268 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01468961 0,09132608 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01468961 0,09109071 ! negative chemotaxis GO:0050919 14 5 0,000 0,01468961 0,09085654 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01468961 0,09062357 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01468961 0,0903918 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01468961 0,09016121 ! behavioral response to pain GO:0048266 9 5 0,000 0,01468961 0,08993179 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01468961 0,08970354 ! Notch receptor processing GO:0007220 8 5 0,000 0,01468961 0,08947644 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01468961 0,08925049 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01468961 0,08902568 ! micturition GO:0060073 9 5 0,000 0,01468961 0,088802 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01468961 0,08857943 ! copulation GO:0007620 9 5 0,000 0,01468961 0,08835799 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01468961 0,08813764 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01468961 0,08791839 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01468961 0,08770023 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01468961 0,08748315 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01468961 0,08726715 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01468961 0,0870522 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01468961 0,08683832 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01468961 0,08662548 ! grooming behavior GO:0007625 6 5 0,000 0,01468961 0,08641368 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01468961 0,08620291 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01468961 0,08599317 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01468961 0,08578445 ! response to protozoan GO:0001562 10 5 0,000 0,01468961 0,08557674 ! lymph vessel development GO:0001945 10 5 0,000 0,01468961 0,08537003 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01468961 0,08516432 ! endochondral ossification GO:0001958 16 5 0,000 0,01468961 0,0849596 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01468961 0,08475586 ! parathyroid gland development GO:0060017 13 5 0,000 0,01468961 0,0845531 ! anagen GO:0042640 6 5 0,000 0,01468961 0,0843513 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01468961 0,08415046 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01468961 0,08395058 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01468961 0,08375165 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01468961 0,08355365 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01468961 0,08335659 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01468961 0,08316046 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01468961 0,08296524 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01468961 0,08277095 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01468961 0,08257756 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01468961 0,08238507 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01468961 0,08219347 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01468961 0,08200277 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01468961 0,08181295 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01468961 0,08162401 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01468961 0,08143593 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01468961 0,08124872 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01468961 0,08106237 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01468961 0,08087687 ! histidine catabolic process GO:0006548 6 5 0,000 0,01468961 0,08069222 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01468961 0,08050842 ! microvillus organization GO:0032528 7 5 0,000 0,01468961 0,08032544 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01468961 0,0801433 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01468961 0,07996198 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01468961 0,07978148 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01468961 0,07960179 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01468961 0,07942291 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01468961 0,07924483 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01468961 0,07906755 ! polyol catabolic process GO:0046174 7 5 0,000 0,01468961 0,07889106 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01468961 0,07871535 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01468961 0,07854043 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01468961 0,07836628 ! muscle cell migration GO:0014812 8 5 0,000 0,01468961 0,07819291 ! mitochondrial fission GO:0000266 8 5 0,000 0,01468961 0,0780203 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01468961 0,07784845 ! mRNA transcription GO:0009299 9 5 0,000 0,01468961 0,07767735 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01468961 0,077507 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01468961 0,07733741 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01468961 0,07716855 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01468961 0,07700042 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01468961 0,07683303 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01468961 0,07666636 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01468961 0,07650042 ! response to food GO:0032094 6 5 0,000 0,01468961 0,07633519 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01468961 0,07617068 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01468961 0,07600687 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01468961 0,07584376 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01468961 0,07568136 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01468961 0,07551965 ! forebrain neuron development GO:0021884 13 5 0,000 0,01468961 0,07535862 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01468961 0,07519829 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01468961 0,07503863 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01468961 0,07487965 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01468961 0,07472134 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01468961 0,0745637 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01468961 0,07440672 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01468961 0,07425041 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01468961 0,07409475 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01468961 0,07393974 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01468961 0,07378537 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01468961 0,07363165 ! basic amino acid transport GO:0015802 11 5 0,000 0,01468961 0,07347857 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01468961 0,07332613 ! depyrimidination GO:0045008 10 5 0,000 0,01468961 0,07317432 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01468961 0,07302313 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01468961 0,07287257 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01468961 0,07272262 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01468961 0,07257329 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01468961 0,07242458 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01468961 0,07227647 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01468961 0,07212897 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01468961 0,07198207 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01468961 0,07183576 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01468961 0,07169005 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01468961 0,07154493 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01468961 0,07140039 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01468961 0,07125644 ! response to arsenic GO:0046685 10 5 0,000 0,01468961 0,07111307 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01468961 0,07097027 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01468961 0,07082804 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01468961 0,07068639 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01468961 0,0705453 ! response to cadmium ion GO:0046686 7 5 0,000 0,01468961 0,07040477 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01468961 0,0702648 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01468961 0,07012539 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01468961 0,06998652 ! decidualization GO:0046697 11 5 0,000 0,01468961 0,06984821 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01468961 0,06971044 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01468961 0,06957322 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01468961 0,06943653 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01468961 0,06930038 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01468961 0,06916476 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01468961 0,06902968 ! neural tube patterning GO:0021532 7 5 0,000 0,01468961 0,06889512 ! embryonic cleavage GO:0040016 6 5 0,000 0,01468961 0,06876108 ! peroxisome fission GO:0016559 5 5 0,000 0,01468961 0,06862756 ! histone demethylation GO:0016577 10 5 0,000 0,01468961 0,06849456 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01468961 0,06836208 ! mitotic recombination GO:0006312 9 5 0,000 0,01468961 0,0682301 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01468961 0,06809864 ! metaphase plate congression GO:0051310 7 5 0,000 0,01468961 0,06796768 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01468961 0,06783722 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01468961 0,06770727 ! enteric nervous system development GO:0048484 8 5 0,000 0,01468961 0,06757781 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01468961 0,06744884 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01468961 0,06732037 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01468961 0,06719238 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01468961 0,06706488 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01468961 0,06693787 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01468961 0,06681133 ! plasminogen activation GO:0031639 5 5 0,000 0,01468961 0,06668527 ! B cell homeostasis GO:0001782 13 5 0,000 0,01468961 0,06655969 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01468961 0,06643458 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01468961 0,06630993 ! metaphase GO:0051323 8 5 0,000 0,01468961 0,06618576 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01468961 0,06606205 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01468961 0,0659388 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01468961 0,065816 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01468961 0,06569367 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01468961 0,06557179 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01468961 0,06545036 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01468961 0,06532938 ! response to redox state GO:0051775 5 5 0,000 0,01468961 0,06520885 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01468961 0,06508876 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01468961 0,06496911 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01468961 0,0648499 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01468961 0,06473112 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01468961 0,06461279 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01468961 0,06449488 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01468961 0,0643774 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01468961 0,06426035 ! striatum development GO:0021756 9 5 0,000 0,01468961 0,06414373 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01468961 0,06402753 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01468961 0,06391174 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01468961 0,06379638 ! glial cell migration GO:0008347 11 5 0,000 0,01468961 0,06368143 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01468961 0,0635669 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01468961 0,06345277 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01468961 0,06333906 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01468961 0,06322575 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01468961 0,06311285 ! neuroprotection GO:0043526 6 5 0,000 0,01468961 0,06300035 ! neural plate development GO:0001840 8 5 0,000 0,01468961 0,06288825 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01468961 0,06277654 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01468961 0,06266524 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01468961 0,06255433 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01468961 0,06244381 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01468961 0,06233368 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01468961 0,06222393 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01468961 0,06211458 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01468961 0,0620056 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01468961 0,06189701 ! spindle assembly GO:0051225 6 5 0,000 0,01468961 0,0617888 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01468961 0,06168097 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01468961 0,06157351 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01468961 0,06146642 ! drug metabolic process GO:0017144 6 5 0,000 0,01468961 0,06135971 ! stem cell division GO:0017145 11 5 0,000 0,01468961 0,06125337 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01468961 0,06114739 ! organ regeneration GO:0031100 7 5 0,000 0,01468961 0,06104179 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01468961 0,06093654 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01468961 0,06083166 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01468961 0,06072714 ! germ cell development GO:0007281 118 65 1,000 0,01591986 0,06570013 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,01638617 0,06750879 ! actin filament organization GO:0007015 148 66 1,000 0,01638617 0,06739339 ! developmental maturation GO:0021700 116 66 1,000 0,01638617 0,06727838 ! viral reproduction GO:0016032 134 68 1,000 0,01733617 0,07105764 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01733617 0,07093679 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01760182 0,0719015 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01760182 0,07177963 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01760182 0,07165818 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01760182 0,07153714 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01760182 0,0714165 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01760182 0,07129627 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01760182 0,07117644 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01760182 0,07105702 ! sleep GO:0030431 13 6 0,000 0,01760182 0,070938 ! response to oxygen radical GO:0000305 11 6 0,000 0,01760182 0,07081937 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01760182 0,07070114 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01760182 0,07058331 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01760182 0,07046586 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01760182 0,07034881 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01760182 0,07023215 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01760182 0,07011587 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01760182 0,06999997 ! forebrain regionalization GO:0021871 8 6 0,000 0,01760182 0,06988446 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01760182 0,06976933 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01760182 0,06965458 ! response to zinc ion GO:0010043 9 6 0,000 0,01760182 0,0695402 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01760182 0,0694262 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01760182 0,06931258 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01760182 0,06919932 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01760182 0,06908643 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01760182 0,06897392 ! malate metabolic process GO:0006108 11 6 0,000 0,01760182 0,06886176 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01760182 0,06874997 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01760182 0,06863855 ! protein refolding GO:0042026 15 6 0,000 0,01760182 0,06852748 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01760182 0,06841678 ! opsonization GO:0008228 8 6 0,000 0,01760182 0,06830643 ! mating behavior GO:0007617 7 6 0,000 0,01760182 0,06819643 ! neuron remodeling GO:0016322 15 6 0,000 0,01760182 0,06808679 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01760182 0,0679775 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01760182 0,06786856 ! equilibrioception GO:0050957 14 6 0,000 0,01760182 0,06775997 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01760182 0,06765173 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01760182 0,06754383 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01760182 0,06743628 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01760182 0,06732907 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01760182 0,0672222 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01760182 0,06711566 ! toxin metabolic process GO:0009404 11 6 0,000 0,01760182 0,06700947 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01760182 0,06690361 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01760182 0,06679808 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01760182 0,06669289 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,01760182 0,06658803 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,01760182 0,06648349 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01760182 0,06637929 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01760182 0,06627541 ! thymic T cell selection GO:0045061 12 6 0,000 0,01760182 0,06617185 ! protein lipoylation GO:0009249 10 6 0,000 0,01760182 0,06606862 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01760182 0,06596571 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01760182 0,06586312 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01760182 0,06576084 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01760182 0,06565889 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01760182 0,06555725 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01760182 0,06545593 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01760182 0,06535491 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01760182 0,06525421 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01760182 0,06515382 ! hyperosmotic response GO:0006972 9 6 0,000 0,01760182 0,06505374 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01760182 0,06495396 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01760182 0,06485449 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01760182 0,06475533 ! urea metabolic process GO:0019627 7 6 0,000 0,01760182 0,06465646 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01760182 0,0645579 ! neutrophil activation GO:0042119 8 6 0,000 0,01760182 0,06445964 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01760182 0,06436168 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01760182 0,06426401 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01760182 0,06416664 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01760182 0,06406957 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01760182 0,06397279 ! neuron apoptosis GO:0051402 9 6 0,000 0,01760182 0,0638763 ! nucleoside salvage GO:0043174 9 6 0,000 0,01760182 0,0637801 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01760182 0,06368419 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01760182 0,06358856 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01760182 0,06349323 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01760182 0,06339818 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01760182 0,06330341 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01760182 0,06320893 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01760182 0,06311473 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01760182 0,06302081 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01760182 0,06292717 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01760182 0,0628338 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01760182 0,06274072 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01760182 0,06264791 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01760182 0,06255537 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01760182 0,0624631 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01760182 0,06237111 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01760182 0,06227939 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01760182 0,06218794 ! neural nucleus development GO:0048857 14 6 0,000 0,01760182 0,06209675 ! astrocyte development GO:0014002 15 6 0,000 0,01760182 0,06200583 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01760182 0,06191518 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01760182 0,06182479 ! interaction with symbiont GO:0051702 13 6 0,000 0,01760182 0,06173467 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01760182 0,06164481 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01760182 0,06155521 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01760182 0,06146587 ! response to copper ion GO:0046688 10 6 0,000 0,01760182 0,06137679 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01760182 0,06128797 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01760182 0,0611994 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01760182 0,06111109 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01760182 0,06102303 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01760182 0,06093523 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01760182 0,06084768 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01760182 0,06076038 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01760182 0,06067333 ! hair follicle maturation GO:0048820 7 6 0,000 0,01760182 0,06058653 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01760182 0,06049998 ! Schwann cell development GO:0014044 15 6 0,000 0,01760182 0,06041367 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01760182 0,06032761 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01760182 0,0602418 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01760182 0,06015623 ! subpallium development GO:0021544 10 6 0,000 0,01760182 0,0600709 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01760182 0,05998581 ! histone ubiquitination GO:0016574 8 6 0,000 0,01760182 0,05990097 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01760182 0,05981636 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01760182 0,05973199 ! G2 phase GO:0051319 16 6 0,000 0,01760182 0,05964786 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01760182 0,05956397 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01760182 0,05948031 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01760182 0,05939689 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01760182 0,0593137 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01760182 0,05923075 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01760182 0,05914802 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01760182 0,05906553 ! receptor internalization GO:0031623 10 6 0,000 0,01760182 0,05898326 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01760182 0,05890123 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01760182 0,05881942 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01760182 0,05873784 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01760182 0,05865649 ! protein deubiquitination GO:0016579 14 6 0,000 0,01760182 0,05857536 ! protein destabilization GO:0031648 9 6 0,000 0,01760182 0,05849445 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01760182 0,05841377 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01760182 0,05833331 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01760182 0,05825307 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01760182 0,05817306 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01760182 0,05809326 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01760182 0,05801368 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01760182 0,05793431 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01760182 0,05785517 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01760182 0,05777624 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01760182 0,05769753 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01760182 0,05761903 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01760182 0,05754074 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01760182 0,05746266 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01760182 0,0573848 ! catecholamine transport GO:0051937 9 6 0,000 0,01760182 0,05730715 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01760182 0,05722971 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01760182 0,05715248 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01760182 0,05707545 ! maternal placenta development GO:0001893 12 6 0,000 0,01760182 0,05699863 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01760182 0,05692202 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01760182 0,05684562 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01760182 0,05676942 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01760182 0,05669342 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01760182 0,05661763 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01760182 0,05654203 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01760182 0,05646665 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,01781979 0,05708976 ! reproductive structure development GO:0048608 113 71 1,000 0,01880405 0,06016295 ! B cell activation GO:0042113 160 71 1,000 0,01880405 0,06008305 ! regulation of caspase activity GO:0043281 122 72 1,000 0,01930462 0,06160069 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,01930462 0,0615191 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 1,000 0,01930462 0,06143772 ! learning or memory GO:0007611 147 73 1,000 0,01981078 0,0629653 ! axon guidance GO:0007411 139 73 1,000 0,01981078 0,06288223 ! meiosis GO:0007126 121 74 1,000 0,02032248 0,06442144 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,02032248 0,06433668 ! tRNA transcription GO:0009304 14 7 0,000 0,02050553 0,06483088 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,02050553 0,0647458 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,02050553 0,06466094 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,02050553 0,0645763 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,02050553 0,06449189 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,02050553 0,0644077 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,02050553 0,06432372 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,02050553 0,06423997 ! prostate gland development GO:0030850 13 7 0,000 0,02050553 0,06415643 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,02050553 0,06407311 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02050553 0,06399001 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,02050553 0,06390712 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,02050553 0,06382445 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02050553 0,06374199 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,02050553 0,06365974 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,02050553 0,0635777 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,02050553 0,06349588 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,02050553 0,06341426 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,02050553 0,06333286 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,02050553 0,06325166 ! glycolipid transport GO:0046836 10 7 0,000 0,02050553 0,06317067 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,02050553 0,06308989 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,02050553 0,06300932 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,02050553 0,06292895 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,02050553 0,06284879 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,02050553 0,06276882 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,02050553 0,06268907 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,02050553 0,06260951 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,02050553 0,06253016 ! mRNA stabilization GO:0048255 18 7 0,000 0,02050553 0,06245101 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,02050553 0,06237206 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,02050553 0,0622933 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,02050553 0,06221475 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,02050553 0,06213639 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02050553 0,06205823 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,02050553 0,06198027 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,02050553 0,0619025 ! lipoprotein transport GO:0042953 14 7 0,000 0,02050553 0,06182493 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02050553 0,06174755 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02050553 0,06167037 ! rhythmic behavior GO:0007622 15 7 0,000 0,02050553 0,06159338 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,02050553 0,06151658 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,02050553 0,06143997 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,02050553 0,06136355 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,02050553 0,06128732 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,02050553 0,06121129 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,02050553 0,06113544 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,02050553 0,06105977 ! mechanosensory behavior GO:0007638 14 7 0,000 0,02050553 0,0609843 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,02050553 0,06090901 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02050553 0,0608339 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,02050553 0,06075899 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02050553 0,06068425 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02050553 0,0606097 ! spinal cord patterning GO:0021511 13 7 0,000 0,02050553 0,06053533 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,02050553 0,06046115 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,02050553 0,06038714 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,02050553 0,06031332 ! adrenal gland development GO:0030325 17 7 0,000 0,02050553 0,06023968 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,02050553 0,06016622 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,02050553 0,06009293 ! ovulation GO:0030728 9 7 0,000 0,02050553 0,06001983 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,02050553 0,0599469 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,02050553 0,05987415 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,02050553 0,05980157 ! microtubule nucleation GO:0007020 20 7 0,000 0,02050553 0,05972917 ! proline biosynthetic process GO:0006561 10 7 0,000 0,02050553 0,05965695 ! thyroid hormone generation GO:0006590 13 7 0,000 0,02050553 0,0595849 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,02050553 0,05951302 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,02050553 0,05944132 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,02050553 0,05936979 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02050553 0,05929843 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02050553 0,05922725 ! galactose metabolic process GO:0006012 13 7 0,000 0,02050553 0,05915623 ! vesicle fusion GO:0006906 17 7 0,000 0,02050553 0,05908538 ! response to dietary excess GO:0002021 8 7 0,000 0,02050553 0,05901471 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,02050553 0,0589442 ! intracellular pH reduction GO:0051452 11 7 0,000 0,02050553 0,05887386 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,02050553 0,05880369 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,02050553 0,05873369 ! purine salvage GO:0043101 10 7 0,000 0,02050553 0,05866385 ! nucleoside transport GO:0015858 8 7 0,000 0,02050553 0,05859418 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,02050553 0,05852467 ! parturition GO:0007567 14 7 0,000 0,02050553 0,05845533 ! rRNA modification GO:0000154 14 7 0,000 0,02050553 0,05838615 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,02050553 0,05831714 ! spindle checkpoint GO:0031577 15 7 0,000 0,02050553 0,05824828 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,02050553 0,05817959 ! macrophage differentiation GO:0030225 11 7 0,000 0,02050553 0,05811107 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02050553 0,0580427 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,02050553 0,0579745 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,02050553 0,05790645 ! fibrinolysis GO:0042730 10 7 0,000 0,02050553 0,05783857 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,02050553 0,05777084 ! eating behavior GO:0042755 7 7 0,000 0,02050553 0,05770327 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,02050553 0,05763586 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,02050553 0,05756861 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,02050553 0,05750151 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,02050553 0,05743457 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,02050553 0,05736779 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,02050553 0,05730116 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,02050553 0,05723468 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,02050553 0,05716836 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,02050553 0,05710219 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,02050553 0,05703618 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,02050553 0,05697032 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,02050553 0,05690461 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,02050553 0,05683905 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,02050553 0,05677364 ! regulation of meiosis GO:0040020 12 7 0,000 0,02050553 0,05670839 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,02050553 0,05664328 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,02050553 0,05657832 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,02050553 0,05651351 ! oxygen homeostasis GO:0032364 12 7 0,000 0,02050553 0,05644885 ! transcription termination GO:0006353 13 7 0,000 0,02050553 0,05638434 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,02050553 0,05631997 ! anaphase GO:0051322 17 7 0,000 0,02050553 0,05625575 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,02050553 0,05619168 ! axonal fasciculation GO:0007413 18 7 0,000 0,02050553 0,05612775 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,02050553 0,05606397 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,02050553 0,05600034 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,02050553 0,05593684 ! diuresis GO:0030146 12 7 0,000 0,02050553 0,0558735 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,02050553 0,05581029 ! thiamin metabolic process GO:0006772 7 7 0,000 0,02050553 0,05574723 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02050553 0,05568431 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,02050553 0,05562153 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,02050553 0,05555889 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,02050553 0,0554964 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02050553 0,05543404 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02050553 0,05537183 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02050553 0,05530975 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,02050553 0,05524781 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,02050553 0,05518601 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,02050553 0,05512435 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,02050553 0,05506283 ! lymph node development GO:0048535 10 7 0,000 0,02050553 0,05500145 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,02050553 0,0549402 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02050553 0,05487908 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,02050553 0,05481811 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,02050553 0,05475727 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,02050553 0,05469656 ! adult feeding behavior GO:0008343 9 7 0,000 0,02050553 0,05463599 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,02050553 0,05457555 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,02050553 0,05451524 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,02050553 0,05445507 ! muscle adaptation GO:0043500 14 7 0,000 0,02050553 0,05439503 ! embryonic heart tube development GO:0035050 10 7 0,000 0,02050553 0,05433513 ! retina homeostasis GO:0001895 12 7 0,000 0,02050553 0,05427535 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,02050553 0,05421571 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,02050553 0,0541562 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,02050553 0,05409682 ! protein prenylation GO:0018342 18 7 0,000 0,02050553 0,05403756 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,02050553 0,05397844 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,02050553 0,05391945 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02050553 0,05386059 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,02083968 0,0546786 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,02083968 0,05461904 ! meiotic cell cycle GO:0051321 122 75 1,000 0,02083968 0,0545596 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,02083968 0,0545003 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,02136236 0,05580655 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,02189047 0,05712416 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,02242398 0,05845299 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,02296286 0,0597929 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,02296286 0,05972826 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,02296286 0,05966376 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02340074 0,06073591 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02340074 0,06067046 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02340074 0,06060516 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02340074 0,06053999 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02340074 0,06047496 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02340074 0,06041008 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02340074 0,06034533 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02340074 0,06028072 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02340074 0,06021625 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02340074 0,06015191 ! meiotic prophase I GO:0007128 13 8 0,000 0,02340074 0,06008772 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02340074 0,06002366 ! oligopeptide transport GO:0006857 15 8 0,000 0,02340074 0,05995973 ! UTP metabolic process GO:0046051 8 8 0,000 0,02340074 0,05989595 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02340074 0,0598323 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02340074 0,05976878 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02340074 0,0597054 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02340074 0,05964215 ! succinate metabolic process GO:0006105 14 8 0,000 0,02340074 0,05957904 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02340074 0,05951606 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02340074 0,05945321 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02340074 0,0593905 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02340074 0,05932791 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02340074 0,05926546 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02340074 0,05920314 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02340074 0,05914096 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02340074 0,0590789 ! reflex GO:0060004 16 8 0,000 0,02340074 0,05901697 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02340074 0,05895517 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02340074 0,0588935 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02340074 0,05883196 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02340074 0,05877055 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02340074 0,05870927 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02340074 0,05864812 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02340074 0,05858709 ! pigment granule organization GO:0048753 16 8 0,000 0,02340074 0,05852619 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02340074 0,05846541 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02340074 0,05840476 ! histidine metabolic process GO:0006547 16 8 0,000 0,02340074 0,05834424 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02340074 0,05828384 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02340074 0,05822357 ! glycine catabolic process GO:0006546 13 8 0,000 0,02340074 0,05816342 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02340074 0,0581034 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02340074 0,0580435 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02340074 0,05798372 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02340074 0,05792406 ! melanin metabolic process GO:0006582 15 8 0,000 0,02340074 0,05786453 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02340074 0,05780512 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02340074 0,05774584 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02340074 0,05768667 ! macrophage activation GO:0042116 12 8 0,000 0,02340074 0,05762763 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02340074 0,0575687 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02340074 0,0575099 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02340074 0,05745121 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02340074 0,05739265 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02340074 0,05733421 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02340074 0,05727588 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02340074 0,05721767 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02340074 0,05715958 ! osteoblast development GO:0002076 16 8 0,000 0,02340074 0,05710161 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02340074 0,05704376 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02340074 0,05698602 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02340074 0,0569284 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02340074 0,0568709 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02340074 0,05681351 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02340074 0,05675624 ! response to UV-B GO:0010224 16 8 0,000 0,02340074 0,05669908 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02340074 0,05664204 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02340074 0,05658512 ! intermediate filament organization GO:0045109 12 8 0,000 0,02340074 0,0565283 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02340074 0,05647161 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02340074 0,05641502 ! cellular extravasation GO:0045123 12 8 0,000 0,02340074 0,05635855 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02340074 0,05630219 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02340074 0,05624594 ! response to antibiotic GO:0046677 11 8 0,000 0,02340074 0,05618981 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02340074 0,05613379 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02340074 0,05607788 ! DNA topological change GO:0006265 12 8 0,000 0,02340074 0,05602208 ! response to tropane GO:0014073 15 8 0,000 0,02340074 0,05596639 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02340074 0,05591081 ! melanosome transport GO:0032402 13 8 0,000 0,02340074 0,05585535 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02340074 0,05579999 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02340074 0,05574474 ! mast cell activation GO:0045576 14 8 0,000 0,02340074 0,0556896 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02340074 0,05563458 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02340074 0,05557965 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02340074 0,05552484 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02340074 0,05547014 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02340074 0,05541554 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02340074 0,05536105 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02340074 0,05530667 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02340074 0,05525239 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02340074 0,05519823 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02340074 0,05514416 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02340074 0,05509021 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02340074 0,05503635 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02340074 0,05498261 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02340074 0,05492897 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02340074 0,05487543 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02340074 0,054822 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02340074 0,05476867 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02340074 0,05471544 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02340074 0,05466232 ! hormone catabolic process GO:0042447 17 8 0,000 0,02340074 0,0546093 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02340074 0,05455639 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02340074 0,05450357 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02340074 0,05445086 ! ATP catabolic process GO:0006200 11 8 0,000 0,02340074 0,05439825 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02340074 0,05434574 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02340074 0,05429334 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02340074 0,05424103 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02340074 0,05418883 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02340074 0,05413672 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02340074 0,05408472 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02340074 0,05403281 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02340074 0,05398101 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02340074 0,0539293 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02340074 0,05387769 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02340074 0,05382619 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02340074 0,05377478 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02340074 0,05372346 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02340074 0,05367225 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02340074 0,05362113 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02340074 0,05357011 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,02350706 0,05376235 ! protein import into nucleus GO:0006606 158 80 1,000 0,02350706 0,05371129 ! T cell activation GO:0042110 168 81 1,000 0,02405656 0,05491469 ! response to hypoxia GO:0001666 171 81 1,000 0,02405656 0,05486263 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,02405656 0,05481068 ! nuclear import GO:0051170 161 81 1,000 0,02405656 0,05475883 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,02461131 0,05596863 ! response to drug GO:0042493 143 82 1,000 0,02461131 0,05591578 ! response to nutrient GO:0007584 125 82 1,000 0,02461131 0,05586303 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,02461131 0,05581038 ! response to oxygen levels GO:0070482 176 83 1,000 0,02517129 0,05702647 ! regulation of lyase activity GO:0051339 160 83 1,000 0,02517129 0,05697283 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,02573645 0,05819727 ! axon extension GO:0048675 15 9 0,000 0,0262875 0,05938754 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,0262875 0,05933182 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,0262875 0,05927622 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,0262875 0,05922072 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0262875 0,05916532 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,0262875 0,05911002 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,0262875 0,05905483 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,0262875 0,05899974 ! phosphate transport GO:0006817 19 9 0,000 0,0262875 0,05894476 ! reproductive behavior GO:0019098 19 9 0,000 0,0262875 0,05888987 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0262875 0,05883509 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,0262875 0,05878041 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,0262875 0,05872584 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,0262875 0,05867136 ! GTP metabolic process GO:0046039 9 9 0,000 0,0262875 0,05861698 ! RNA methylation GO:0001510 15 9 0,000 0,0262875 0,05856271 ! elastic fiber assembly GO:0048251 15 9 0,000 0,0262875 0,05850853 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,0262875 0,05845446 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,0262875 0,05840048 ! artery development GO:0060840 24 9 0,000 0,0262875 0,05834661 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,0262875 0,05829283 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,0262875 0,05823916 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,0262875 0,05818558 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,0262875 0,0581321 ! chemosensory behavior GO:0007635 20 9 0,000 0,0262875 0,05807872 ! microtubule bundle formation GO:0001578 21 9 0,000 0,0262875 0,05802544 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,0262875 0,05797225 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,0262875 0,05791916 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0262875 0,05786617 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,0262875 0,05781328 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,0262875 0,05776048 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,0262875 0,05770778 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,0262875 0,05765517 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0262875 0,05760266 ! protein targeting to ER GO:0045047 22 9 0,000 0,0262875 0,05755025 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,0262875 0,05749793 ! T cell selection GO:0045058 23 9 0,000 0,0262875 0,05744571 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,0262875 0,05739358 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,0262875 0,05734155 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,0262875 0,05728961 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0262875 0,05723776 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,0262875 0,05718601 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0262875 0,05713435 ! mannose metabolic process GO:0006013 13 9 0,000 0,0262875 0,05708278 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,0262875 0,05703131 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,0262875 0,05697993 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,0262875 0,05692865 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,0262875 0,05687745 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0262875 0,05682635 ! ruffle organization GO:0031529 15 9 0,000 0,0262875 0,05677534 ! retinol metabolic process GO:0042572 18 9 0,000 0,0262875 0,05672442 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,0262875 0,05667359 ! behavioral fear response GO:0001662 22 9 0,000 0,0262875 0,05662285 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,0262875 0,05657221 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,0262875 0,05652165 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,0262875 0,05647118 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,0262875 0,05642081 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,0262875 0,05637052 ! segment specification GO:0007379 13 9 0,000 0,0262875 0,05632033 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0262875 0,05627022 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,0262875 0,0562202 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0262875 0,05617027 ! response to amine stimulus GO:0014075 13 9 0,000 0,0262875 0,05612043 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0262875 0,05607068 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,0262875 0,05602101 ! erythrocyte development GO:0048821 15 9 0,000 0,0262875 0,05597144 ! gas homeostasis GO:0033483 16 9 0,000 0,0262875 0,05592195 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,0262875 0,05587255 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,0262875 0,05582323 ! renal water homeostasis GO:0003091 14 9 0,000 0,0262875 0,05577401 ! postreplication repair GO:0006301 22 9 0,000 0,0262875 0,05572487 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,0262875 0,05567581 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,0262875 0,05562685 ! icosanoid secretion GO:0032309 15 9 0,000 0,0262875 0,05557797 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0262875 0,05552917 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,0262875 0,05548046 ! regulation of cell division GO:0051302 15 9 0,000 0,0262875 0,05543184 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,0262875 0,0553833 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,0262875 0,05533484 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,0262875 0,05528647 ! sterol catabolic process GO:0016127 11 9 0,000 0,0262875 0,05523819 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,0262875 0,05518999 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,0262875 0,05514187 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,0262875 0,05509384 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,0262875 0,05504589 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,0262875 0,05499802 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,0262875 0,05495024 ! musculoskeletal movement GO:0050881 14 9 0,000 0,0262875 0,05490254 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,0262875 0,05485492 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,0262875 0,05480739 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0262875 0,05475994 ! purine base metabolic process GO:0006144 21 9 0,000 0,0262875 0,05471257 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,0262875 0,05466528 ! pigment granule transport GO:0051904 17 9 0,000 0,0262875 0,05461807 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,0262875 0,05457094 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,0262875 0,0545239 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,0262875 0,05447694 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,0262875 0,05443006 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0262875 0,05438325 ! mitochondrion localization GO:0051646 15 9 0,000 0,0262875 0,05433653 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,02630676 0,05432968 GO:0002696|positive regulation of leukocyte activation, ! mitochondrion organization GO:0007005 148 86 1,000 0,02688219 0,05547046 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,02746271 0,05661978 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 1,000 0,02746271 0,0565713 ! positive regulation of protein modification process GO:0031401 136 88 1,000 0,02804827 0,0577281 ! regulation of neurological system process GO:0031644 148 88 1,000 0,02804827 0,05767876 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,02863885 0,05884294 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02916582 0,05987454 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02916582 0,05982349 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02916582 0,05977254 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02916582 0,05972167 ! synapsis GO:0007129 13 10 0,000 0,02916582 0,05967088 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02916582 0,05962019 ! N-glycan processing GO:0006491 20 10 0,000 0,02916582 0,05956958 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02916582 0,05951905 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02916582 0,05946861 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02916582 0,05941826 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02916582 0,05936799 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02916582 0,0593178 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02916582 0,0592677 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02916582 0,05921769 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02916582 0,05916776 ! androgen metabolic process GO:0008209 17 10 0,000 0,02916582 0,05911791 ! phospholipid efflux GO:0033700 16 10 0,000 0,02916582 0,05906815 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02916582 0,05901847 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02916582 0,05896887 ! lung alveolus development GO:0048286 26 10 0,000 0,02916582 0,05891936 ! pathogenesis GO:0009405 13 10 0,000 0,02916582 0,05886993 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02916582 0,05882059 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02916582 0,05877132 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02916582 0,05872214 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02916582 0,05867304 ! endoderm development GO:0007492 16 10 0,000 0,02916582 0,05862403 ! arginine catabolic process GO:0006527 13 10 0,000 0,02916582 0,05857509 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02916582 0,05852624 ! proline metabolic process GO:0006560 13 10 0,000 0,02916582 0,05847747 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02916582 0,05842878 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02916582 0,05838017 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02916582 0,05833164 ! V(D)J recombination GO:0033151 28 10 0,000 0,02916582 0,05828319 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02916582 0,05823482 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02916582 0,05818653 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02916582 0,05813833 ! B cell proliferation GO:0042100 18 10 0,000 0,02916582 0,0580902 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02916582 0,05804215 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02916582 0,05799418 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02916582 0,05794629 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02916582 0,05789848 ! epithelial cell development GO:0002064 20 10 0,000 0,02916582 0,05785075 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02916582 0,0578031 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02916582 0,05775552 ! macroautophagy GO:0016236 17 10 0,000 0,02916582 0,05770803 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02916582 0,05766061 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02916582 0,05761327 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02916582 0,057566 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02916582 0,05751882 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02916582 0,05747171 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02916582 0,05742468 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02916582 0,05737773 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02916582 0,05733085 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02916582 0,05728405 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02916582 0,05723732 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02916582 0,05719068 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02916582 0,0571441 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02916582 0,05709761 ! response to dsRNA GO:0043331 20 10 0,000 0,02916582 0,05705119 ! DNA ligation GO:0006266 19 10 0,000 0,02916582 0,05700484 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02916582 0,05695857 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02916582 0,05691238 ! melanosome localization GO:0032400 16 10 0,000 0,02916582 0,05686626 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02916582 0,05682021 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02916582 0,05677424 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02916582 0,05672834 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02916582 0,05668252 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02916582 0,05663677 ! mRNA cleavage GO:0006379 17 10 0,000 0,02916582 0,0565911 ! protein sumoylation GO:0016925 15 10 0,000 0,02916582 0,0565455 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02916582 0,05649997 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02916582 0,05645451 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02916582 0,05640913 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02916582 0,05636382 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02916582 0,05631859 ! salivary gland development GO:0007431 27 10 0,000 0,02916582 0,05627342 ! prophase GO:0051324 15 10 0,000 0,02916582 0,05622833 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02916582 0,05618331 ! apical protein localization GO:0045176 15 10 0,000 0,02916582 0,05613837 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02916582 0,05609349 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02916582 0,05604869 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02916582 0,05600396 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02916582 0,0559593 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02916582 0,05591471 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02916582 0,05587019 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02916582 0,05582574 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02916582 0,05578137 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02916582 0,05573706 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02916582 0,05569282 ! detection of calcium ion GO:0005513 23 10 0,000 0,02916582 0,05564866 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02916582 0,05560456 ! blastocyst formation GO:0001825 17 10 0,000 0,02916582 0,05556054 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02916582 0,05551658 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02916582 0,0554727 ! activation of innate immune response GO:0002218 12 10 0,000 0,02916582 0,05542888 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02916582 0,05538513 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02916582 0,05534145 ! response to nicotine GO:0035094 20 10 0,000 0,02916582 0,05529784 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02916582 0,0552543 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02916582 0,05521083 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02916582 0,05516742 ! ossification GO:0001503 188 90 1,000 0,02923441 0,05525373 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,02923441 0,05521036 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,02923441 0,05516705 ! sex differentiation GO:0007548 145 90 1,000 0,02923441 0,05512382 ! bone development GO:0060348 189 91 1,000 0,02983492 0,05621207 ! regulation of defense response GO:0031347 149 92 1,000 0,03044034 0,05730786 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,03105063 0,05841112 ! regulation of membrane potential GO:0042391 164 93 1,000 0,03105063 0,05836549 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,03105063 0,05831993 ! regulation of T cell activation GO:0050863 158 94 1,000 0,03166578 0,05942891 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,03203572 0,06007635 ! respiratory burst GO:0045730 17 11 0,000 0,03203572 0,06002956 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,03203572 0,05998284 ! neuron fate specification GO:0048665 17 11 0,000 0,03203572 0,0599362 ! telencephalon cell migration GO:0022029 20 11 0,000 0,03203572 0,05988963 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,03203572 0,05984313 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,03203572 0,0597967 ! thyroid gland development GO:0030878 26 11 0,000 0,03203572 0,05975035 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,03203572 0,05970407 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,03203572 0,05965786 ! response to pain GO:0048265 24 11 0,000 0,03203572 0,05961172 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03203572 0,05956565 ! T cell proliferation GO:0042098 26 11 0,000 0,03203572 0,05951965 ! blood vessel remodeling GO:0001974 29 11 0,000 0,03203572 0,05947373 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,03203572 0,05942787 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,03203572 0,05938209 ! bone resorption GO:0045453 16 11 0,000 0,03203572 0,05933638 ! ventral spinal cord development GO:0021517 21 11 0,000 0,03203572 0,05929073 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03203572 0,05924516 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03203572 0,05919966 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,03203572 0,05915422 ! melanocyte differentiation GO:0030318 21 11 0,000 0,03203572 0,05910886 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,03203572 0,05906356 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,03203572 0,05901834 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,03203572 0,05897318 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,03203572 0,0589281 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,03203572 0,05888308 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,03203572 0,05883813 ! UV protection GO:0009650 19 11 0,000 0,03203572 0,05879325 ! adult heart development GO:0007512 14 11 0,000 0,03203572 0,05874844 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,03203572 0,0587037 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03203572 0,05865902 ! temperature homeostasis GO:0001659 17 11 0,000 0,03203572 0,05861441 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,03203572 0,05856987 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,03203572 0,0585254 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,03203572 0,058481 ! regulation of organ growth GO:0046620 13 11 0,000 0,03203572 0,05843666 ! pigment granule localization GO:0051875 20 11 0,000 0,03203572 0,05839239 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,03203572 0,05834818 ! vasoconstriction GO:0042310 18 11 0,000 0,03203572 0,05830405 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03203572 0,05825998 ! embryonic axis specification GO:0000578 18 11 0,000 0,03203572 0,05821598 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,03203572 0,05817204 ! snRNA metabolic process GO:0016073 24 11 0,000 0,03203572 0,05812817 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03203572 0,05808436 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,03203572 0,05804063 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03203572 0,05799695 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,03203572 0,05795335 ! zymogen activation GO:0031638 15 11 0,000 0,03203572 0,05790981 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,03203572 0,05786633 ! neuroblast proliferation GO:0007405 24 11 0,000 0,03203572 0,05782292 ! nucleosome positioning GO:0016584 15 11 0,000 0,03203572 0,05777957 ! regulation of isotype switching GO:0045191 22 11 0,000 0,03203572 0,05773629 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,03203572 0,05769308 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,03203572 0,05764993 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,03203572 0,05760684 ! acid secretion GO:0046717 18 11 0,000 0,03203572 0,05756382 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03203572 0,05752086 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,03203572 0,05747797 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,03203572 0,05743514 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,03203572 0,05739237 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,03203572 0,05734967 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,03203572 0,05730703 ! cholesterol efflux GO:0033344 19 11 0,000 0,03203572 0,05726445 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,03203572 0,05722194 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03203572 0,05717949 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,03203572 0,0571371 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,03203572 0,05709478 ! embryonic gut development GO:0048566 15 11 0,000 0,03203572 0,05705252 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,03203572 0,05701032 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,03203572 0,05696818 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,03203572 0,05692611 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,03203572 0,0568841 ! defense response to fungus GO:0050832 13 11 0,000 0,03203572 0,05684215 ! lysogeny GO:0030069 21 11 0,000 0,03203572 0,05680026 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03203572 0,05675843 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,03203572 0,05671667 ! sequestering of metal ion GO:0051238 14 11 0,000 0,03203572 0,05667496 ! lamellipodium assembly GO:0030032 20 11 0,000 0,03203572 0,05663332 ! nucleus localization GO:0051647 19 11 0,000 0,03203572 0,05659174 ! regulation of synapse organization GO:0050807 17 11 0,000 0,03203572 0,05655022 ! leukocyte differentiation GO:0002521 202 96 1,000 0,03291047 0,05805176 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,03481303 0,06136275 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03489724 0,06146615 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03489724 0,06142119 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03489724 0,06137629 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03489724 0,06133145 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03489724 0,06128669 ! cartilage condensation GO:0001502 20 12 0,000 0,03489724 0,06124198 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,03489724 0,06119735 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,03489724 0,06115278 ! protein complex disassembly GO:0043241 27 12 0,000 0,03489724 0,06110827 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,03489724 0,06106383 ! hippocampus development GO:0021766 26 12 0,000 0,03489724 0,06101945 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03489724 0,06097514 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03489724 0,06093089 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03489724 0,0608867 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03489724 0,06084258 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03489724 0,06079852 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03489724 0,06075453 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03489724 0,0607106 ! drug transport GO:0015893 16 12 0,000 0,03489724 0,06066673 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03489724 0,06062293 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03489724 0,06057919 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03489724 0,06053552 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03489724 0,0604919 ! focal adhesion formation GO:0048041 35 12 0,000 0,03489724 0,06044835 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03489724 0,06040486 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03489724 0,06036144 ! forebrain cell migration GO:0021885 21 12 0,000 0,03489724 0,06031808 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03489724 0,06027477 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03489724 0,06023154 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03489724 0,06018836 ! entry into host cell GO:0030260 32 12 0,000 0,03489724 0,06014524 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,03489724 0,06010219 ! monoamine transport GO:0015844 18 12 0,000 0,03489724 0,0600592 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03489724 0,06001627 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03489724 0,0599734 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03489724 0,05993059 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03489724 0,05988785 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03489724 0,05984516 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03489724 0,05980254 ! protein homotetramerization GO:0051289 21 12 0,000 0,03489724 0,05975997 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03489724 0,05971747 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03489724 0,05967503 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03489724 0,05963264 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03489724 0,05959032 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03489724 0,05954806 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03489724 0,05950585 ! cranial nerve development GO:0021545 20 12 0,000 0,03489724 0,05946371 ! fucose catabolic process GO:0019317 22 12 0,000 0,03489724 0,05942163 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03489724 0,0593796 ! histone methylation GO:0016571 26 12 0,000 0,03489724 0,05933764 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03489724 0,05929574 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03489724 0,05925389 ! gland morphogenesis GO:0022612 29 12 0,000 0,03489724 0,0592121 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03489724 0,05917037 ! T cell homeostasis GO:0043029 25 12 0,000 0,03489724 0,0591287 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03489724 0,05908709 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03489724 0,05904554 ! spleen development GO:0048536 22 12 0,000 0,03489724 0,05900405 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03489724 0,05896261 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03489724 0,05892124 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03489724 0,05887992 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03489724 0,05883866 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03489724 0,05879745 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,03489724 0,05875631 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03489724 0,05871522 ! response to cold GO:0009409 17 12 0,000 0,03489724 0,05867419 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03489724 0,05863321 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03489724 0,0585923 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03775039 0,06333853 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,03775039 0,06329439 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03775039 0,06325031 ! peroxisomal transport GO:0043574 24 13 0,000 0,03775039 0,06320629 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,03775039 0,06316234 ! lipid localization GO:0010876 28 13 0,000 0,03775039 0,06311845 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,03775039 0,06307461 ! organelle fusion GO:0048284 32 13 0,000 0,03775039 0,06303084 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,03775039 0,06298713 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,03775039 0,06294348 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,03775039 0,06289989 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,03775039 0,06285636 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,03775039 0,06281289 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,03775039 0,06276949 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03775039 0,06272614 ! methionine metabolic process GO:0006555 27 13 0,000 0,03775039 0,06268285 ! plasma membrane organization GO:0007009 24 13 0,000 0,03775039 0,06263962 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,03775039 0,06259645 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,03775039 0,06255334 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,03775039 0,06251029 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,03775039 0,06246729 ! cytokine metabolic process GO:0042107 22 13 0,000 0,03775039 0,06242436 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,03775039 0,06238149 ! exocrine system development GO:0035272 32 13 0,000 0,03775039 0,06233867 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,03775039 0,06229592 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,03775039 0,06225322 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,03775039 0,06221058 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,03775039 0,062168 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,03775039 0,06212548 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,03775039 0,06208301 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,03775039 0,0620406 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,03775039 0,06199826 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,03775039 0,06195597 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03775039 0,06191373 ! ribosome assembly GO:0042255 17 13 0,000 0,03775039 0,06187156 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,03775039 0,06182944 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,03775039 0,06178738 ! chromatin silencing GO:0006342 26 13 0,000 0,03775039 0,06174537 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,03775039 0,06170343 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03775039 0,06166154 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03775039 0,0616197 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,03775039 0,06157793 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,03775039 0,06153621 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,03775039 0,06149455 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03775039 0,06145294 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,03775039 0,06141139 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,03775039 0,0613699 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,03775039 0,06132846 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,03775039 0,06128707 ! embryonic placenta development GO:0001892 23 13 0,000 0,03775039 0,06124575 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,03775039 0,06120448 ! insulin secretion GO:0030073 23 13 0,000 0,03775039 0,06116326 ! actin filament polymerization GO:0030041 24 13 0,000 0,03775039 0,0611221 ! acrosome reaction GO:0007340 18 13 0,000 0,03775039 0,061081 ! rRNA transcription GO:0009303 25 14 0,000 0,0405952 0,06563983 ! lactation GO:0007595 26 14 0,000 0,0405952 0,06559574 ! reproductive cellular process GO:0048610 20 14 0,000 0,0405952 0,06555172 ! tRNA modification GO:0006400 20 14 0,000 0,0405952 0,06550775 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,0405952 0,06546385 ! water transport GO:0006833 21 14 0,000 0,0405952 0,06542 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,0405952 0,06537621 ! non-recombinational repair GO:0000726 25 14 0,000 0,0405952 0,06533248 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,0405952 0,06528881 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,0405952 0,0652452 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,0405952 0,06520164 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,0405952 0,06515815 ! RNA polyadenylation GO:0043631 30 14 0,000 0,0405952 0,06511471 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,0405952 0,06507133 ! palate development GO:0060021 31 14 0,000 0,0405952 0,065028 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,0405952 0,06498474 ! regulated secretory pathway GO:0045055 23 14 0,000 0,0405952 0,06494153 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,0405952 0,06489838 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,0405952 0,06485529 ! arginine metabolic process GO:0006525 17 14 0,000 0,0405952 0,06481225 ! regulation of heart rate GO:0002027 24 14 0,000 0,0405952 0,06476927 ! organic alcohol transport GO:0015850 29 14 0,000 0,0405952 0,06472635 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,0405952 0,06468348 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,0405952 0,06464068 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,0405952 0,06459792 ! neutral amino acid transport GO:0015804 26 14 0,000 0,0405952 0,06455523 ! L-amino acid transport GO:0015807 30 14 0,000 0,0405952 0,06451259 ! bone mineralization GO:0030282 17 14 0,000 0,0405952 0,06447001 ! stem cell development GO:0048864 43 14 0,000 0,0405952 0,06442748 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,0405952 0,06438501 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,0405952 0,0643426 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,0405952 0,06430024 ! cerebellum development GO:0021549 21 14 0,000 0,0405952 0,06425794 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,0405952 0,06421569 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,0405952 0,0641735 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,0405952 0,06413136 ! cofactor transport GO:0051181 26 14 0,000 0,0405952 0,06408928 ! NADP metabolic process GO:0006739 24 14 0,000 0,0405952 0,06404725 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,0405952 0,06400528 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,0405952 0,06396337 ! intestinal absorption GO:0050892 25 14 0,000 0,0405952 0,06392151 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,0405952 0,0638797 ! oxygen transport GO:0015671 21 14 0,000 0,0405952 0,06383795 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,0405952 0,06379625 ! male genitalia development GO:0030539 24 14 0,000 0,0405952 0,06375461 ! regulation of RNA stability GO:0043487 32 14 0,000 0,0405952 0,06371302 ! regulation of axon extension GO:0030516 37 14 0,000 0,0405952 0,06367149 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,0405952 0,06363001 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0434317 0,06803169 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0434317 0,06798742 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,0434317 0,06794322 ! superoxide anion generation GO:0042554 20 15 0,000 0,0434317 0,06789907 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,0434317 0,06785498 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0434317 0,06781095 ! copper ion transport GO:0006825 20 15 0,000 0,0434317 0,06776697 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0434317 0,06772305 ! sulfate transport GO:0008272 23 15 0,000 0,0434317 0,06767919 ! response to cAMP GO:0051591 22 15 0,000 0,0434317 0,06763539 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0434317 0,06759164 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,0434317 0,06754794 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0434317 0,06750431 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0434317 0,06746073 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0434317 0,06741721 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0434317 0,06737374 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,0434317 0,06733033 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0434317 0,06728697 ! pituitary gland development GO:0021983 29 15 0,000 0,0434317 0,06724367 ! vesicle coating GO:0006901 33 15 0,000 0,0434317 0,06720043 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,0434317 0,06715724 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0434317 0,06711411 ! regulation of exocytosis GO:0017157 22 15 0,000 0,0434317 0,06707103 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0434317 0,06702801 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0434317 0,06698505 ! regulation of vasodilation GO:0042312 26 15 0,000 0,0434317 0,06694213 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,0434317 0,06689928 ! histone deacetylation GO:0016575 20 15 0,000 0,0434317 0,06685648 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0434317 0,06681373 ! tissue regeneration GO:0042246 26 15 0,000 0,0434317 0,06677104 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0434317 0,0667284 ! water homeostasis GO:0030104 27 15 0,000 0,0434317 0,06668581 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0434317 0,06664328 ! muscle maintenance GO:0046716 26 15 0,000 0,0434317 0,06660081 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,0434317 0,06655839 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,0434317 0,06651602 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0434317 0,06647371 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0434317 0,06643145 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0434317 0,06638924 ! cell killing GO:0001906 29 15 0,000 0,0434317 0,06634709 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,0434317 0,06630499 ! detection of bacterium GO:0016045 18 15 0,000 0,0434317 0,06626295 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0434317 0,06622096 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0434317 0,06617902 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0434317 0,06613713 ! peptide hormone processing GO:0016486 23 15 0,000 0,0434317 0,0660953 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,0462599 0,07035482 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,0462599 0,07031038 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,0462599 0,07026599 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,0462599 0,07022166 ! bone remodeling GO:0046849 27 16 0,000 0,0462599 0,07017738 ! filopodium assembly GO:0046847 32 16 0,000 0,0462599 0,07013316 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,0462599 0,070089 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,0462599 0,07004489 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,0462599 0,07000084 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,0462599 0,06995684 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,0462599 0,06991289 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,0462599 0,06986901 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,0462599 0,06982517 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,0462599 0,0697814 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,0462599 0,06973767 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,0462599 0,06969401 ! protein polyubiquitination GO:0000209 34 16 0,000 0,0462599 0,06965039 ! glutamate metabolic process GO:0006536 22 16 0,000 0,0462599 0,06960683 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,0462599 0,06956333 ! response to osmotic stress GO:0006970 25 16 0,000 0,0462599 0,06951988 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,0462599 0,06947648 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,0462599 0,06943314 ! fructose metabolic process GO:0006000 25 16 0,000 0,0462599 0,06938986 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,0462599 0,06934662 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,0462599 0,06930344 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,0462599 0,06926032 ! negative regulation of immune response GO:0050777 35 16 0,000 0,0462599 0,06921724 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,0462599 0,06917422 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,0462599 0,06913126 ! DNA replication initiation GO:0006270 27 16 0,000 0,0462599 0,06908835 ! neuron recognition GO:0008038 35 16 0,000 0,0462599 0,06904549 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,0462599 0,06900268 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,0462599 0,06895993 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,0462599 0,06891723 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,0462599 0,06887458 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,0462599 0,06883199 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,0462599 0,06878945 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,0462599 0,06874696 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,0462599 0,06870452 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,0462599 0,06866214 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,0462599 0,06861981 ! defense response to virus GO:0051607 37 16 0,000 0,0462599 0,06857753 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,04907984 0,07271311 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,04907984 0,07266836 ! metencephalon development GO:0022037 30 17 0,000 0,04907984 0,07262367 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,04907984 0,07257904 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,04907984 0,07253445 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,04907984 0,07248993 ! endothelial cell migration GO:0043542 28 17 0,000 0,04907984 0,07244546 ! inositol metabolic process GO:0006020 28 17 0,000 0,04907984 0,07240104 ! gene silencing by RNA GO:0031047 36 17 0,000 0,04907984 0,07235667 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,04907984 0,07231236 ! glial cell development GO:0021782 27 17 0,000 0,04907984 0,07226811 ! limbic system development GO:0021761 36 17 0,000 0,04907984 0,07222391 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,04907984 0,07217976 ! adult walking behavior GO:0007628 33 17 0,000 0,04907984 0,07213567 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,04907984 0,07209163 ! heart looping GO:0001947 30 17 0,000 0,04907984 0,07204765 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,04907984 0,07200371 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,04907984 0,07195984 ! myoblast differentiation GO:0045445 45 17 0,000 0,04907984 0,07191601 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,04907984 0,07187224 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,04907984 0,07182852 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,04907984 0,07178486 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,04907984 0,07174125 ! glycine metabolic process GO:0006544 28 17 0,000 0,04907984 0,07169769 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,04907984 0,07165418 ! NAD metabolic process GO:0019674 29 17 0,000 0,04907984 0,07161073 ! membrane budding GO:0006900 37 17 0,000 0,04907984 0,07156733 ! DNA integration GO:0015074 29 17 0,000 0,04907984 0,07152398 ! regulation of protein binding GO:0043393 33 17 0,000 0,04907984 0,07148069 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,04907984 0,07143744 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,04907984 0,07139425 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,04907984 0,07135111 ! genitalia development GO:0048806 30 17 0,000 0,04907984 0,07130803 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,04907984 0,07126499 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,04907984 0,07122201 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,04907984 0,07117908 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,04907984 0,0711362 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,04907984 0,07109337 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,04907984 0,0710506 ! steroid catabolic process GO:0006706 31 17 0,000 0,04907984 0,07100787 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,04907984 0,0709652 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,04907984 0,07092258 ! gas transport GO:0015669 25 17 0,000 0,04907984 0,07088001 ! organic cation transport GO:0015695 31 17 0,000 0,04907984 0,07083749 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,04907984 0,07079502 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,04907984 0,0707526 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,04907984 0,07071023 ! microspike assembly GO:0030035 36 17 0,000 0,04907984 0,07066792 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,04907984 0,07062565 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,04907984 0,07058344 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,05189153 0,07458245 ! neuron maturation GO:0042551 42 18 0,000 0,05189153 0,07453792 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,05189153 0,07449345 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,05189153 0,07444903 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,05189153 0,07440466 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,05189153 0,07436035 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,05189153 0,07431608 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05189153 0,07427187 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,05189153 0,07422772 ! patterning of blood vessels GO:0001569 39 18 0,000 0,05189153 0,07418361 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,05189153 0,07413956 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,05189153 0,07409556 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,05189153 0,07405161 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05189153 0,07400772 ! response to retinoic acid GO:0032526 26 18 0,000 0,05189153 0,07396387 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,05189153 0,07392008 ! response to fungus GO:0009620 21 18 0,000 0,05189153 0,07387634 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,05189153 0,07383266 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,05189153 0,07378902 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,05189153 0,07374543 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,05189153 0,0737019 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,05189153 0,07365842 ! vitamin transport GO:0051180 27 18 0,000 0,05189153 0,07361499 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,05189153 0,07357161 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,05189153 0,07352828 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,05189153 0,073485 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,05189153 0,07344178 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,05189153 0,0733986 ! nerve development GO:0021675 28 18 0,000 0,05189153 0,07335548 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,05189153 0,0733124 ! protein secretion GO:0009306 39 19 0,000 0,054695 0,0772278 ! positive regulation of translation GO:0045727 30 19 0,000 0,054695 0,0771825 ! negative regulation of defense response GO:0031348 25 19 0,000 0,054695 0,07713726 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,054695 0,07709207 ! skin development GO:0043588 36 19 0,000 0,054695 0,07704694 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,054695 0,07700185 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,054695 0,07695682 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,054695 0,07691185 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,054695 0,07686692 ! bile acid metabolic process GO:0008206 29 19 0,000 0,054695 0,07682205 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,054695 0,07677723 ! cerebral cortex development GO:0021987 36 19 0,000 0,054695 0,07673246 ! pigmentation during development GO:0048066 41 19 0,000 0,054695 0,07668774 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,054695 0,07664308 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,054695 0,07659847 ! heme metabolic process GO:0042168 36 19 0,000 0,054695 0,07655391 ! actin filament bundle formation GO:0051017 42 19 0,000 0,054695 0,0765094 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,054695 0,07646494 ! plasma membrane fusion GO:0045026 28 19 0,000 0,054695 0,07642054 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,054695 0,07637619 ! peptide cross-linking GO:0018149 37 19 0,000 0,054695 0,07633189 ! protein export from nucleus GO:0006611 36 19 0,000 0,054695 0,07628763 ! heart process GO:0003015 30 19 0,000 0,054695 0,07624344 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,054695 0,07619929 ! visual learning GO:0008542 36 19 0,000 0,054695 0,07615519 ! cellular pigmentation GO:0033059 36 19 0,000 0,054695 0,07611115 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,054695 0,07606715 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,054695 0,07602321 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,054695 0,07597931 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,054695 0,07593547 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,054695 0,07589168 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,054695 0,07584794 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,054695 0,07580425 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,054695 0,0757606 ! cilium assembly GO:0042384 37 19 0,000 0,054695 0,07571701 ! peptide hormone secretion GO:0030072 31 19 0,000 0,054695 0,07567347 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,05749027 0,07949517 ! positive regulation of ossification GO:0045778 47 20 0,000 0,05749027 0,07944951 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,05749027 0,0794039 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,05749027 0,07935835 ! cAMP metabolic process GO:0046058 36 20 0,000 0,05749027 0,07931284 ! response to vitamin GO:0033273 31 20 0,000 0,05749027 0,07926739 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,05749027 0,07922199 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,05749027 0,07917664 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,05749027 0,07913135 ! response to alkaloid GO:0043279 38 20 0,000 0,05749027 0,07908611 ! retinoid metabolic process GO:0001523 32 20 0,000 0,05749027 0,07904091 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,05749027 0,07899577 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,05749027 0,07895068 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,05749027 0,07890565 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,05749027 0,07886066 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,05749027 0,07881573 ! body fluid secretion GO:0007589 31 20 0,000 0,05749027 0,07877084 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,05749027 0,07872601 ! peptide secretion GO:0002790 35 20 0,000 0,05749027 0,07868123 ! stem cell differentiation GO:0048863 53 20 0,000 0,05749027 0,0786365 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,05749027 0,07859182 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,05749027 0,07854719 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,05749027 0,07850261 ! sensory perception of pain GO:0019233 30 20 0,000 0,05749027 0,07845808 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,05749027 0,0784136 ! diencephalon development GO:0021536 34 20 0,000 0,05749027 0,07836918 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,05749027 0,0783248 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,05749027 0,07828047 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,05749027 0,0782362 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,05749027 0,07819197 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,05749027 0,0781478 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,05749027 0,07810367 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,05749027 0,07805959 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,05749027 0,07801557 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,05749027 0,07797159 ! regulation of glucose import GO:0046324 29 20 0,000 0,05749027 0,07792766 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,05749027 0,07788378 ! actin filament-based movement GO:0030048 43 20 0,000 0,05749027 0,07783995 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,05749027 0,07779617 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,05749027 0,07775244 ! negative regulation of translation GO:0017148 29 20 0,000 0,05749027 0,07770876 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,05749027 0,07766513 ! regulation of cell killing GO:0031341 42 21 0,000 0,06027737 0,0813846 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,06027737 0,08133896 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,06027737 0,08129336 ! hormone secretion GO:0046879 38 21 0,000 0,06027737 0,08124782 ! glycerol metabolic process GO:0006071 34 21 0,000 0,06027737 0,08120233 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,06027737 0,08115689 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,06027737 0,0811115 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,06027737 0,08106616 ! axis specification GO:0009798 38 21 0,000 0,06027737 0,08102087 ! ovarian follicle development GO:0001541 35 21 0,000 0,06027737 0,08097563 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,06027737 0,08093045 ! smooth muscle contraction GO:0006939 46 21 0,000 0,06027737 0,08088531 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,06027737 0,08084022 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,06027737 0,08079519 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,06027737 0,0807502 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,06027737 0,08070527 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,06027737 0,08066038 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,06027737 0,08061554 ! cytolysis GO:0019835 24 21 0,000 0,06027737 0,08057076 ! vasodilation GO:0042311 39 21 0,000 0,06027737 0,08052602 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,06027737 0,08048133 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,06027737 0,0804367 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,06027737 0,08039211 ! DNA modification GO:0006304 34 21 0,000 0,06027737 0,08034757 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,06027737 0,08030308 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,06027737 0,08025864 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,06027737 0,08021425 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,06027737 0,08016991 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,06027737 0,08012561 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,06027737 0,08008137 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,06027737 0,08003718 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,06027737 0,07999303 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,06027737 0,07994893 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,06027737 0,07990488 ! collagen catabolic process GO:0030574 28 21 0,000 0,06027737 0,07986088 ! sperm-egg recognition GO:0035036 21 21 0,000 0,06027737 0,07981693 ! gut development GO:0048565 39 21 0,000 0,06027737 0,07977303 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,06305633 0,0834049 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,06305633 0,08335908 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,06305633 0,0833133 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,06305633 0,08326757 GO:0034105|positive regulation of tissue remodeling, ! regulation of chemotaxis GO:0050920 40 22 0,000 0,06305633 0,0832219 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,06305633 0,08317627 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,06305633 0,0831307 ! regeneration GO:0031099 41 22 0,000 0,06305633 0,08308517 ! keratinization GO:0031424 28 22 0,000 0,06305633 0,08303969 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,06305633 0,08299427 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,06305633 0,08294889 ! sensory perception of taste GO:0050909 28 22 0,000 0,06305633 0,08290356 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,06305633 0,08285828 ! vacuolar transport GO:0007034 36 22 0,000 0,06305633 0,08281306 ! lysosome organization GO:0007040 41 22 0,000 0,06305633 0,08276788 ! central nervous system neuron development GO:0021954 46 22 0,000 0,06305633 0,08272275 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,06305633 0,08267767 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,06305633 0,08263264 ! fucose metabolic process GO:0006004 39 22 0,000 0,06305633 0,08258765 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,06305633 0,08254272 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,06305633 0,08249783 ! ureteric bud development GO:0001657 43 22 0,000 0,06305633 0,082453 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,06305633 0,08240821 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,06305633 0,08236347 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,06305633 0,08231878 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,06305633 0,08227414 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,06305633 0,08222955 ! sarcomere organization GO:0045214 30 22 0,000 0,06305633 0,082185 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,06305633 0,08214051 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,06305633 0,08209606 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,06305633 0,08205166 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,06305633 0,08200731 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,06582715 0,08556463 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,06582715 0,08551843 ! gluconeogenesis GO:0006094 33 23 0,000 0,06582715 0,08547227 ! viral genome replication GO:0019079 41 23 0,000 0,06582715 0,08542617 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,06582715 0,08538012 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,06582715 0,08533412 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,06582715 0,08528817 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,06582715 0,08524226 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,06582715 0,08519641 ! visual behavior GO:0007632 42 23 0,000 0,06582715 0,0851506 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,06582715 0,08510485 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,06582715 0,08505914 ! response to ethanol GO:0045471 46 23 0,000 0,06582715 0,08501349 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,06582715 0,08496788 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,06582715 0,08492232 ! peroxisome organization GO:0007031 37 23 0,000 0,06582715 0,08487681 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,06582715 0,08483135 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,06582715 0,08478593 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,06582715 0,08474057 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,06582715 0,08469525 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,06582715 0,08464999 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,06582715 0,08460477 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,06582715 0,0845596 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,06582715 0,08451447 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,06582715 0,0844694 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,06582715 0,08442437 ! fatty acid transport GO:0015908 44 23 0,000 0,06582715 0,08437939 ! platelet activation GO:0030168 37 23 0,000 0,06582715 0,08433446 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,06582715 0,08428958 ! hormone transport GO:0009914 40 23 0,000 0,06582715 0,08424475 ! cell-cell recognition GO:0009988 25 23 0,000 0,06582715 0,08419996 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,06582715 0,08415522 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,06582715 0,08411053 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,06582715 0,08406588 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,06582715 0,08402129 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,06858987 0,08750119 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,06858987 0,08745481 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,06858987 0,08740849 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,06858987 0,08736222 ! vesicle docking GO:0048278 47 24 0,000 0,06858987 0,087316 ! spinal cord development GO:0021510 47 24 0,000 0,06858987 0,08726982 ! vacuole organization GO:0007033 43 24 0,000 0,06858987 0,0872237 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,06858987 0,08717762 ! digestive system process GO:0022600 39 24 0,000 0,06858987 0,08713159 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,06858987 0,08708561 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,06858987 0,08703968 ! regulation of behavior GO:0050795 43 24 0,000 0,06858987 0,0869938 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,06858987 0,08694796 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,06858987 0,08690218 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,06858987 0,08685644 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,06858987 0,08681075 ! membrane depolarization GO:0051899 39 24 0,000 0,06858987 0,08676511 ! pallium development GO:0021543 49 24 0,000 0,06858987 0,08671951 ! pentose metabolic process GO:0019321 35 24 0,000 0,06858987 0,08667397 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,06858987 0,08662847 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,06858987 0,08658302 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,06858987 0,08653762 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,06858987 0,08649226 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,06858987 0,08644695 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,06858987 0,08640169 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,06858987 0,08635648 ! regulation of amine transport GO:0051952 40 24 0,000 0,06858987 0,08631132 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,07134452 0,08973074 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,07134452 0,08968386 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,07134452 0,08963703 ! phototransduction GO:0007602 33 25 0,000 0,07134452 0,08959024 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,07134452 0,08954351 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,07134452 0,08949682 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,07134452 0,08945019 ! chromosome condensation GO:0030261 45 25 0,000 0,07134452 0,0894036 ! osteoblast differentiation GO:0001649 60 25 0,000 0,07134452 0,08935706 ! neural crest cell development GO:0014032 54 25 0,000 0,07134452 0,08931057 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,07134452 0,08926412 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,07134452 0,08921773 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,07134452 0,08917138 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,07134452 0,08912508 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,07134452 0,08907883 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,07134452 0,08903263 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,07134452 0,08898647 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,07134452 0,08894037 ! telomere organization GO:0032200 43 25 0,000 0,07134452 0,08889431 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,07134452 0,0888483 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,07134452 0,08880233 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,07409111 0,09217332 ! embryonic pattern specification GO:0009880 44 26 0,000 0,07409111 0,09212569 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,07409111 0,0920781 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,07409111 0,09203056 ! initiation of viral infection GO:0019059 57 26 0,000 0,07409111 0,09198308 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,07409111 0,09193564 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,07409111 0,09188825 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,07409111 0,09184091 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,07409111 0,09179362 ! molting cycle process GO:0022404 50 26 0,000 0,07409111 0,09174637 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,07409111 0,09169918 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,07409111 0,09165203 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,07409111 0,09160493 ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,07409111 0,09155788 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,07409111 0,09151088 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,07409111 0,09146393 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,07409111 0,09141703 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,07409111 0,09137017 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,07409111 0,09132336 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,07409111 0,0912766 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,07409111 0,09122989 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,07409111 0,09118322 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,07409111 0,09113661 ! leukocyte proliferation GO:0070661 52 26 0,000 0,07409111 0,09109004 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,07409111 0,09104351 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,07409111 0,09099704 ! neuron fate commitment GO:0048663 48 27 0,000 0,07682966 0,09431233 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,07682966 0,09426424 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,07682966 0,09421619 ! iron ion transport GO:0006826 59 27 0,000 0,07682966 0,09416819 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,07682966 0,09412025 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,07682966 0,09407235 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,07682966 0,0940245 ! fat cell differentiation GO:0045444 50 27 0,000 0,07682966 0,0939767 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,07682966 0,09392895 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,07682966 0,09388124 ! autophagy GO:0006914 41 27 0,000 0,07682966 0,09383359 ! male gonad development GO:0008584 44 27 0,000 0,07682966 0,09378598 ! response to toxin GO:0009636 47 27 0,000 0,07682966 0,09373842 ! primary neural tube formation GO:0014020 51 27 0,000 0,07682966 0,09369091 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,07682966 0,09364345 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,07682966 0,09359603 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,07682966 0,09354867 ! glutathione metabolic process GO:0006749 39 27 0,000 0,07682966 0,09350135 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,07682966 0,09345408 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,07682966 0,09340686 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,07682966 0,09335968 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,07956021 0,09662891 ! circadian rhythm GO:0007623 50 28 0,000 0,07956021 0,09658015 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,07956021 0,09653145 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,07956021 0,09648279 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,07956021 0,09643419 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,07956021 0,09638563 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,07956021 0,09633712 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,07956021 0,09628866 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,07956021 0,09624025 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,07956021 0,09619189 ! synaptogenesis GO:0007416 42 28 0,000 0,07956021 0,09614358 ! lipid oxidation GO:0034440 43 28 0,000 0,07956021 0,09609531 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,07956021 0,0960471 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,07956021 0,09599893 ! translational initiation GO:0006413 65 29 0,000 0,08228277 0,09923426 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,08228277 0,09918454 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,08228277 0,09913487 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,08228277 0,09908526 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,08228277 0,09903569 ! catechol metabolic process GO:0009712 54 29 0,000 0,08228277 0,09898617 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,08228277 0,0989367 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,08228277 0,09888729 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,08228277 0,09883792 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,08228277 0,0987886 ! cell fate determination GO:0001709 60 29 0,000 0,08228277 0,09873932 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,08228277 0,0986901 ! detection of light stimulus GO:0009583 38 29 0,000 0,08228277 0,09864093 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,08228277 0,09859181 ! tissue homeostasis GO:0001894 48 29 0,000 0,08228277 0,09854273 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,08228277 0,0984937 ! phenol metabolic process GO:0018958 55 30 0,000 0,08499737 0,10169253 ! zinc ion transport GO:0006829 45 30 0,000 0,08499737 0,10164198 ! membrane docking GO:0022406 61 30 0,000 0,08499737 0,10159149 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,08499737 0,10154105 ! regulation of innate immune response GO:0045088 51 30 0,000 0,08499737 0,10149065 ! acute-phase response GO:0006953 49 30 0,000 0,08499737 0,10144031 ! myofibril assembly GO:0030239 47 30 0,000 0,08499737 0,10139002 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,08499737 0,10133978 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,08499737 0,10128958 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,08499737 0,10123944 ! phospholipid transport GO:0015914 51 30 0,000 0,08499737 0,10118935 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,08499737 0,1011393 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,08499737 0,10108931 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,08499737 0,10103936 ! eye morphogenesis GO:0048592 60 30 0,000 0,08499737 0,10098947 ! response to heat GO:0009408 50 30 0,000 0,08499737 0,10093962 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,08770403 0,10410256 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,08770403 0,10405123 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,08770403 0,10399995 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,08770403 0,10394871 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,08770403 0,10389753 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,08770403 0,1038464 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,08770403 0,10379532 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,08770403 0,10374429 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,08770403 0,10369331 ! ovulation cycle process GO:0022602 49 31 0,000 0,08770403 0,10364238 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,08770403 0,1035915 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,08770403 0,10354067 ! peptide transport GO:0015833 55 31 0,000 0,08770403 0,10348989 ! iron ion homeostasis GO:0055072 54 31 0,000 0,08770403 0,10343916 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,08770403 0,10338848 ! mesoderm formation GO:0001707 69 31 0,000 0,08770403 0,10333785 ! natural killer cell activation GO:0030101 45 31 0,000 0,08770403 0,10328727 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,08770403 0,10323674 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,08770403 0,10318625 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,08770403 0,10313582 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,08770403 0,10308544 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,09040277 0,1062056 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,09040277 0,10615376 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,09040277 0,10610198 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,09040277 0,10605025 ! cholesterol transport GO:0030301 56 32 0,000 0,09040277 0,10599857 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,09040277 0,10594694 ! spliceosome assembly GO:0000245 67 32 0,000 0,09040277 0,10589536 ! spindle organization GO:0007051 46 32 0,000 0,09040277 0,10584383 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,09040277 0,10579234 ! metanephros development GO:0001656 74 32 0,000 0,09040277 0,10574091 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,09040277 0,10568953 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,09040277 0,1056382 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,09040277 0,10558692 ! muscle cell development GO:0055001 49 32 0,000 0,09040277 0,10553569 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,09040277 0,10548451 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,09040277 0,10543338 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,09040277 0,1053823 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,09040277 0,10533126 ! ovulation cycle GO:0042698 51 32 0,000 0,09040277 0,10528028 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,09040277 0,10522935 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,09040277 0,10517846 ! gene silencing GO:0016458 65 32 0,000 0,09040277 0,10512763 ! post-embryonic development GO:0009791 69 33 0,000 0,09309362 0,10820446 ! protein targeting to membrane GO:0006612 68 33 0,000 0,09309362 0,10815222 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,09309362 0,10810002 ! ceramide metabolic process GO:0006672 64 33 0,000 0,09309362 0,10804787 ! formation of primary germ layer GO:0001704 72 33 0,000 0,09309362 0,10799578 ! sterol transport GO:0015918 57 33 0,000 0,09309362 0,10794373 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,09309362 0,10789173 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,09309362 0,10783979 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,09309362 0,10778789 ! glial cell differentiation GO:0010001 63 34 0,000 0,09577659 0,11084102 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,09577659 0,11078773 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,09577659 0,11073449 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,09577659 0,11068131 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,09577659 0,11062817 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,09577659 0,11057509 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,09577659 0,11052205 ! mismatch repair GO:0006298 46 34 0,000 0,09577659 0,11046907 ! spermatid development GO:0007286 63 34 0,000 0,09577659 0,11041614 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,09577659 0,11036326 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,09577659 0,11031043 ! placenta development GO:0001890 53 34 0,000 0,09577659 0,11025765 ! regulation of muscle development GO:0048634 70 35 0,000 0,09845172 0,11328304 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,09845172 0,11322889 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,09845172 0,11317479 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,09845172 0,11312075 ! odontogenesis GO:0042476 66 35 0,000 0,09845172 0,11306675 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,09845172 0,11301281 ! telencephalon development GO:0021537 68 35 0,000 0,09845172 0,11295891 ! cytokine production GO:0001816 59 35 0,000 0,09845172 0,11290507 ! neural tube formation GO:0001841 67 35 0,000 0,09845172 0,11285128 ! vesicle localization GO:0051648 64 35 0,000 0,09845172 0,11279754 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,10111902 0,11579837 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,10111902 0,11574328 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,10111902 0,11568824 ! positive regulation of cell development GO:0010720 80 36 0,000 0,10111902 0,11563326 ! regulation of proteolysis GO:0030162 72 36 0,000 0,10111902 0,11557832 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,10111902 0,11552344 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,10111902 0,11546861 ! aerobic respiration GO:0009060 55 36 0,000 0,10111902 0,11541384 ! embryonic organ development GO:0048568 57 36 0,000 0,10111902 0,11535911 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,10111902 0,11530444 ! RNA export from nucleus GO:0006405 56 37 0,000 0,10377852 0,11828097 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,10377852 0,11822497 ! meiosis I GO:0007127 65 37 0,000 0,10377852 0,11816901 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,10377852 0,11811312 ! sister chromatid segregation GO:0000819 58 37 0,000 0,10377852 0,11805727 ! actomyosin structure organization GO:0031032 62 37 0,000 0,10377852 0,11800148 ! organic anion transport GO:0015711 68 37 0,000 0,10377852 0,11794574 ! tissue remodeling GO:0048771 76 37 0,000 0,10377852 0,11789005 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,10377852 0,11783442 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,10377852 0,11777883 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,10377852 0,1177233 ! pigment metabolic process GO:0042440 80 37 0,000 0,10377852 0,11766783 ! spermatid differentiation GO:0048515 66 37 0,000 0,10377852 0,1176124 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,10643024 0,12056081 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,10643024 0,12050408 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,10643024 0,1204474 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,10643024 0,12039077 ! nucleus organization GO:0006997 67 38 0,000 0,10643024 0,12033419 ! lipid homeostasis GO:0055088 67 38 0,000 0,10643024 0,12027767 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,10643024 0,1202212 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,10643024 0,12016479 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,10643024 0,12010843 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,10643024 0,12005212 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,10643024 0,11999586 ! glucan metabolic process GO:0044042 62 38 0,000 0,10643024 0,11993965 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,1090742 0,12286167 ! learning GO:0007612 77 39 0,000 0,1090742 0,12280418 ! ear morphogenesis GO:0042471 60 39 0,000 0,1090742 0,12274674 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,1090742 0,12268936 ! ion transmembrane transport GO:0034220 66 39 0,000 0,1090742 0,12263203 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,1090742 0,12257475 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,1090742 0,12251752 ! RNA modification GO:0009451 57 39 0,000 0,1090742 0,12246035 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,1090742 0,12240323 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,11171043 0,12530317 ! feeding behavior GO:0007631 59 40 0,000 0,11171043 0,12524478 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,11171043 0,12518644 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,11171043 0,12512816 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,11433894 0,12801279 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,11433894 0,12795325 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,11433894 0,12789377 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,11433894 0,12783434 ! gliogenesis GO:0042063 88 41 0,000 0,11433894 0,12777496 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,11433894 0,12771564 ! polyol metabolic process GO:0019751 66 41 0,000 0,11433894 0,12765638 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,11433894 0,12759717 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,11695976 0,13046138 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,11695976 0,13040092 ! regulation of tube size GO:0035150 71 42 0,000 0,11695976 0,13034052 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,11695976 0,13028018 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,11695976 0,13021989 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,11695976 0,13015966 ! neuron migration GO:0001764 79 42 0,000 0,11695976 0,13009949 ! regulation of protein secretion GO:0050708 71 42 0,000 0,11695976 0,13003937 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,11695976 0,1299793 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,11957292 0,13282199 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,11957292 0,1327607 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,11957292 0,13269946 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,11957292 0,13263828 ! glucose transport GO:0015758 65 43 0,000 0,11957292 0,13257716 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,11957292 0,13251609 ! neural tube development GO:0021915 77 43 0,000 0,11957292 0,13245508 ! striated muscle contraction GO:0006941 77 43 0,000 0,11957292 0,13239413 ! phagocytosis GO:0006909 90 43 0,000 0,11957292 0,13233323 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,11957292 0,13227239 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,12217842 0,1350925 ! hexose transport GO:0008645 67 44 0,000 0,12217842 0,13503045 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,12217842 0,13496845 ! male sex differentiation GO:0046661 76 44 0,000 0,12217842 0,13490651 ! biopolymer methylation GO:0043414 84 44 0,000 0,12217842 0,13484463 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,12217842 0,1347828 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,12217842 0,13472103 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,12477631 0,13752258 ! glycolysis GO:0006096 65 45 0,000 0,12477631 0,13745961 ! leukocyte migration GO:0050900 68 45 0,000 0,12477631 0,1373967 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,12477631 0,13733385 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,12477631 0,13727105 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,12477631 0,13720831 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,12477631 0,13714563 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,12477631 0,13708301 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,12477631 0,13702044 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,12736659 0,1398011 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,12736659 0,13973735 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,12736659 0,13967366 ! pigmentation GO:0043473 100 46 0,000 0,12736659 0,13961003 ! response to calcium ion GO:0051592 81 47 0,000 0,12994929 0,14237613 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,12994929 0,14231133 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,12994929 0,14224658 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,12994929 0,14218189 ! JNK cascade GO:0007254 91 47 0,000 0,12994929 0,14211726 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,12994929 0,1420527 ! methylation GO:0032259 90 47 0,000 0,12994929 0,14198818 ! protein homooligomerization GO:0051260 76 47 0,000 0,12994929 0,14192373 ! cellular component disassembly GO:0022411 86 48 0,000 0,13252443 0,1446705 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,13252443 0,14460489 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,13252443 0,14453934 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,13252443 0,14447384 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,13252443 0,14440841 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,13509203 0,14713963 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,13509203 0,14707305 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,13509203 0,14700653 ! regulation of ion transport GO:0043269 77 49 0,000 0,13509203 0,14694007 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,13509203 0,14687367 ! peptide metabolic process GO:0006518 76 49 0,000 0,13509203 0,14680733 ! response to temperature stimulus GO:0009266 76 49 0,000 0,13509203 0,14674105 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,13509203 0,14667483 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,13509203 0,14660868 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,13509203 0,14654258 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,13765212 0,14925237 ! inner ear development GO:0048839 79 50 0,000 0,13765212 0,14918514 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,13765212 0,14911797 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,13765212 0,14905086 ! viral infectious cycle GO:0019058 99 51 0,000 0,14020472 0,15174654 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,14020472 0,15167831 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,14020472 0,15161014 ! excretion GO:0007588 83 51 0,000 0,14020472 0,15154203 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,14020472 0,15147398 ! chromatin remodeling GO:0006338 109 51 0,000 0,14020472 0,151406 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,14020472 0,15133807 ! vesicle organization GO:0016050 107 51 0,000 0,14020472 0,15127021 ! regulation of cell shape GO:0008360 125 51 0,000 0,14020472 0,1512024 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,14020472 0,15113466 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,14274985 0,15380929 ! membrane fusion GO:0006944 110 52 0,000 0,14274985 0,15374044 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,14274985 0,15367165 ! amino acid activation GO:0043038 92 52 0,000 0,14274985 0,15360292 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,14274985 0,15353426 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,14528753 0,15619383 ! RNA catabolic process GO:0006401 93 53 0,000 0,14528753 0,15612407 ! regulation of translational initiation GO:0006446 82 53 0,000 0,14528753 0,15605437 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,14528753 0,15598473 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,14528753 0,15591516 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,14528753 0,15584565 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,14528753 0,1557762 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,14781778 0,15841852 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,14781778 0,15834798 ! cell recognition GO:0008037 85 54 0,000 0,14781778 0,15827751 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,14781778 0,1582071 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,14781778 0,15813676 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,14781778 0,15806647 ! chloride transport GO:0006821 90 55 0,000 0,15034062 0,16069281 ! glucose catabolic process GO:0006007 82 55 0,000 0,15034062 0,16062146 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,15034062 0,16055017 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,15034062 0,16047894 ! gastrulation GO:0007369 112 55 0,000 0,15034062 0,16040777 ! RNA elongation GO:0006354 79 55 0,000 0,15034062 0,16033667 ! nuclear export GO:0051168 97 55 0,000 0,15034062 0,16026563 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,15034062 0,16019465 ! regulation of actin filament length GO:0030832 105 56 0,000 0,15285608 0,16280288 ! sensory perception of smell GO:0007608 80 56 0,000 0,15285608 0,16273085 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,15285608 0,16265888 ! proton transport GO:0015992 94 56 0,000 0,15285608 0,16258697 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,15285608 0,16251512 ! hydrogen transport GO:0006818 97 58 0,000 0,15786492 0,16776634 ! regulation of endocytosis GO:0030100 91 58 0,000 0,15786492 0,16769227 ! regulation of cellular component size GO:0032535 109 59 0,000 0,16035835 0,17026575 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,16035835 0,17019065 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,16035835 0,17011561 GO:0032313|regulation of Rab GTPase activity, ! DNA catabolic process GO:0006308 86 59 0,000 0,16035835 0,17004063 ! establishment of organelle localization GO:0051656 109 59 0,000 0,16035835 0,16996572 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,16284448 0,1725248 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,16284448 0,17244887 ! regulation of heart contraction GO:0008016 110 60 0,000 0,16284448 0,172373 ! camera-type eye development GO:0043010 116 60 0,000 0,16284448 0,1722972 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,16284448 0,17222146 ! kidney development GO:0001822 122 60 0,000 0,16284448 0,17214579 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,16532333 0,17468948 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,16532333 0,17461279 ! mesoderm development GO:0007498 119 61 0,000 0,16532333 0,17453617 ! tRNA processing GO:0008033 89 61 0,000 0,16532333 0,17445962 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,16532333 0,17438314 ! ear development GO:0043583 103 62 0,000 0,16779493 0,17691262 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,16779493 0,17683513 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,16779493 0,1767577 ! regulation of mitosis GO:0007088 105 63 0,000 0,17025928 0,1792752 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,17025928 0,17919678 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,17025928 0,17911842 ! detection of external stimulus GO:0009581 91 63 0,000 0,17025928 0,17904014 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,17025928 0,17896192 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,17271643 0,18146538 ! cell redox homeostasis GO:0045454 102 64 0,000 0,17271643 0,18138617 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,17271643 0,18130703 ! single fertilization GO:0007338 75 64 0,000 0,17271643 0,18122796 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,17516637 0,18371852 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,17516637 0,18363847 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,17516637 0,18355849 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 0,000 0,17516637 0,18347858 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,17760914 0,18595631 ! extracellular matrix organization GO:0030198 133 66 0,000 0,17760914 0,18587542 ! secondary metabolic process GO:0019748 116 66 0,000 0,17760914 0,18579461 ! cell projection assembly GO:0030031 120 66 0,000 0,17760914 0,18571386 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,18004476 0,18817884 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,18004476 0,18809713 ! chromosome segregation GO:0007059 113 67 0,000 0,18004476 0,18801549 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,18004476 0,18793393 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,18004476 0,18785243 ! hexose catabolic process GO:0019320 104 67 0,000 0,18004476 0,187771 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,18004476 0,18768964 ! adaptive immune response GO:0002250 119 67 0,000 0,18004476 0,18760836 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,18004476 0,18752714 ! amino acid transport GO:0006865 125 68 0,000 0,18247325 0,18997431 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,18247325 0,18989214 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,18247325 0,18981005 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,18247325 0,18972802 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,18247325 0,18964606 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,18489462 0,19207965 ! urogenital system development GO:0001655 137 69 0,000 0,18489462 0,19199675 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,18489462 0,19191392 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,18489462 0,19183116 ! antigen processing and presentation GO:0019882 104 69 0,000 0,18489462 0,19174848 ! appendage morphogenesis GO:0035107 135 70 0,000 0,18730891 0,19416856 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,18971612 0,19657923 ! appendage development GO:0048736 136 71 0,000 0,18971612 0,19649461 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,18971612 0,19641006 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,18971612 0,19632558 ! regulation of immune effector process GO:0002697 137 71 0,000 0,18971612 0,19624118 ! acute inflammatory response GO:0002526 113 72 0,000 0,19211628 0,19863849 ! carbohydrate transport GO:0008643 110 72 0,000 0,19211628 0,19855317 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,19211628 0,19846791 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,19211628 0,19838273 ! regulation of blood pressure GO:0008217 125 73 0,000 0,19450941 0,20076776 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,19450941 0,20068167 ! fertilization GO:0009566 90 73 0,000 0,19450941 0,20059565 ! transition metal ion transport GO:0000041 126 74 0,000 0,19689554 0,20296943 ! neurotransmitter transport GO:0006836 123 74 0,000 0,19689554 0,20288251 ! exocytosis GO:0006887 133 74 0,000 0,19689554 0,20279566 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,19689554 0,20270888 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,19689554 0,20262218 ! eye development GO:0001654 143 74 0,000 0,19689554 0,20253555 ! organelle localization GO:0051640 136 74 0,000 0,19689554 0,202449 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,19927467 0,20480771 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,19927467 0,20472026 ! rhythmic process GO:0048511 128 75 0,000 0,19927467 0,20463289 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,20164683 0,20698049 ! defense response to bacterium GO:0042742 89 76 0,000 0,20164683 0,20689223 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,20164683 0,20680404 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,20164683 0,20671593 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,20401205 0,20905153 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,20401205 0,20896253 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,20401205 0,20887361 ! blood coagulation GO:0007596 146 78 0,000 0,20637033 0,21119822 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,20637033 0,21110843 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,20637033 0,21101871 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,20872171 0,21333239 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,20872171 0,2132418 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,20872171 0,21315129 ! response to metal ion GO:0010038 140 80 0,000 0,2110662 0,21545409 ! muscle cell differentiation GO:0042692 159 80 0,000 0,2110662 0,21536271 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,2110662 0,21527142 ! inorganic anion transport GO:0015698 138 80 0,000 0,2110662 0,2151802 ! digestion GO:0007586 112 81 0,000 0,21340382 0,21747124 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,21340382 0,21737917 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,21340382 0,21728718 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,21573459 0,21956744 ! hemostasis GO:0007599 158 84 0,000 0,22037567 0,22419614 ! regulation of ligase activity GO:0051340 142 84 0,000 0,22037567 0,22410138 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,22037567 0,2240067 ! response to unfolded protein GO:0006986 131 85 0,000 0,22268601 0,22625952 ! nucleosome assembly GO:0006334 122 85 0,000 0,22268601 0,22616401 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,22268601 0,22606859 ! amine biosynthetic process GO:0009309 138 86 0,000 0,22498959 0,22831082 ! response to inorganic substance GO:0010035 153 86 0,000 0,22498959 0,22821457 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,22498959 0,22811839 ! chromatin assembly GO:0031497 124 86 0,000 0,22498959 0,2280223 ! tube morphogenesis GO:0035239 176 86 0,000 0,22498959 0,22792629 ! alcohol catabolic process GO:0046164 130 86 0,000 0,22498959 0,22783037 ! amine transport GO:0015837 155 86 0,000 0,22498959 0,22773452 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,22728641 0,22996262 ! cellular respiration GO:0045333 135 88 0,000 0,22957651 0,23218204 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,22957651 0,23208448 ! cellular defense response GO:0006968 114 89 0,000 0,23185989 0,23429437 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,23185989 0,23419601 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,23413658 0,2363964 ! sterol metabolic process GO:0016125 152 91 0,000 0,2364066 0,2385882 ! response to protein stimulus GO:0051789 149 91 0,000 0,2364066 0,23848817 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,2364066 0,23838821 ! nucleosome organization GO:0034728 138 92 0,000 0,23866996 0,24056972 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,23866996 0,24046898 ! vitamin metabolic process GO:0006766 139 92 0,000 0,23866996 0,24036833 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,2409267 0,24253959 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,2409267 0,24243816 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,24317681 0,24460009 ! female pregnancy GO:0007565 164 94 0,000 0,24317681 0,24449787 ! transcription initiation GO:0006352 153 94 0,000 0,24317681 0,24439574 ! forebrain development GO:0030900 188 95 0,000 0,24542033 0,24654753 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,24542033 0,24644463 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,24765728 0,24858716 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,24765728 0,24848349 ! positive regulation of immune response GO:0050778 156 96 0,000 0,24765728 0,24837992 ! detection of stimulus GO:0051606 151 96 0,000 0,24765728 0,24827642 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,24988767 0,25040805 ! protein ubiquitination GO:0016567 217 97 0,000 0,24988767 0,2503038 ! response to virus GO:0009615 160 98 0,000 0,25211152 0,25242627 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,25211152 0,25232126 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,25211152 0,25221635 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,25432885 0,25432885