pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6485-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 4,000 1,73E-06 3,98E-03 ! regulation of protein export from nucleus GO:0046825 6 6 2,000 1,264E-05 0,01454077 ! negative regulation of B cell activation GO:0050869 9 6 2,000 1,264E-05 9,694E-03 ! negative regulation of ligase activity GO:0051352 91 61 5,000 1,465E-05 8,423E-03 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of epithelial cell proliferation GO:0050679 37 19 3,000 1,923E-05 8,847E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 4,000 3,43E-05 0,01315014 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 2,000 3,495E-05 0,01148455 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 2,000 3,495E-05 0,01004898 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 3,495E-05 8,932E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 5,000 3,518E-05 8,092E-03 ! negative regulation of phosphorylation GO:0042326 41 23 3,000 4,277E-05 8,942E-03 ! regulation of ligase activity GO:0051340 114 75 5,000 4,807E-05 9,214E-03 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 3,000 6,027E-05 0,01066386 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of lymphocyte activation GO:0051250 37 25 3,000 6,027E-05 9,902E-03 ! regulation of B cell proliferation GO:0030888 15 10 2,000 7,395E-05 0,01133848 ! negative regulation of leukocyte activation GO:0002695 39 27 3,000 8,25E-05 0,01185908 ! regulation of B cell activation GO:0050864 42 28 3,000 9,56E-05 0,01293401 ! anterior/posterior pattern formation GO:0009952 124 85 5,000 9,723E-05 0,01242372 ! negative regulation of mast cell proliferation GO:0070667 17 11 2,000 1,01E-04 0,01222973 GO:0042130|negative regulation of T cell proliferation, ! cell cycle arrest GO:0007050 150 86 5,000 1,038E-04 0,01193462 ! negative regulation of cell activation GO:0050866 44 30 3,000 1,262E-04 0,01382611 ! cell fate commitment GO:0045165 141 92 5,000 1,508E-04 0,01576705 ! lung development GO:0030324 94 59 4,000 1,596E-04 0,01595564 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 4,000 1,729E-04 0,016565 ! N-terminal protein amino acid modification GO:0031365 18 13 2,000 1,729E-04 0,01590596 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 4,000 1,87E-04 0,01654031 ! respiratory tube development GO:0030323 99 62 4,000 2,02E-04 0,01720454 ! mitotic cell cycle checkpoint GO:0007093 63 34 3,000 2,079E-04 0,01708031 ! pituitary gland development GO:0021983 23 14 2,000 2,186E-04 0,01734054 ! regulation of intracellular protein transport GO:0033157 59 35 3,000 2,332E-04 0,01787757 ! cell cycle checkpoint GO:0000075 108 64 4,000 2,347E-04 0,01741139 ! respiratory system development GO:0060541 100 64 4,000 2,347E-04 0,01686728 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 4,000 2,525E-04 0,01759616 ! negative regulation of cell cycle process GO:0010948 24 15 2,000 2,716E-04 0,01837038 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 2,000 2,716E-04 0,01784551 ! negative regulation of leukocyte proliferation GO:0070664 25 15 2,000 2,716E-04 0,0173498 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! diencephalon development GO:0021536 25 16 2,000 3,321E-04 0,02064426 ! regulation of epithelial cell proliferation GO:0050678 71 39 3,000 3,566E-04 0,02158111 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 2,000 4,007E-04 0,02363121 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 3,000 4,755E-04 0,02734166 ! apoptotic mitochondrial changes GO:0008637 29 18 2,000 4,778E-04 0,02680264 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 2,000 4,778E-04 0,02616448 ! negative regulation of T cell activation GO:0050868 25 18 2,000 4,778E-04 0,02555601 ! gland development GO:0048732 148 77 4,000 5,555E-04 0,02903896 ! cell structure disassembly during apoptosis GO:0006921 24 19 2,000 5,638E-04 0,02881465 ! apoptotic nuclear changes GO:0030262 24 19 2,000 5,638E-04 0,02818824 ! positive regulation of intracellular transport GO:0032388 29 19 2,000 5,638E-04 0,02758849 ! embryonic organ morphogenesis GO:0048562 23 19 2,000 5,638E-04 0,02701373 ! regulation of mast cell proliferation GO:0070666 64 44 3,000 5,69E-04 0,02670776 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 4,000 6,62E-04 0,03045131 GO:0010498|proteasomal protein catabolic process, ! regulation of cell cycle process GO:0010564 122 81 4,000 7,007E-04 0,03159807 ! endocrine system development GO:0035270 83 47 3,000 7,327E-04 0,03240637 ! negative regulation of immune system process GO:0002683 73 47 3,000 7,327E-04 0,03179493 ! regulation of leukocyte proliferation GO:0070663 71 47 3,000 7,327E-04 0,03120614 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! negative regulation of bone resorption GO:0045779 10 5 1,000 7,382E-04 0,03087155 ! forebrain regionalization GO:0021871 6 5 1,000 7,382E-04 0,03032027 ! cerebral cortex radially oriented cell migration GO:0021799 8 5 1,000 7,382E-04 0,02978834 ! apoptotic cell clearance GO:0043277 13 5 1,000 7,382E-04 0,02927474 ! lymph vessel development GO:0001945 7 5 1,000 7,382E-04 0,02877856 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 1,000 7,382E-04 0,02829892 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 7,382E-04 0,027835 ! microvillus organization GO:0032528 7 5 1,000 7,382E-04 0,02738605 GO:0030033|microvillus assembly, ! paraxial mesoderm development GO:0048339 9 5 1,000 7,382E-04 0,02695135 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 1,000 7,382E-04 0,02653024 ! substrate-bound cell migration, cell extension GO:0006930 5 5 1,000 7,382E-04 0,02612208 ! cranial nerve morphogenesis GO:0021602 6 5 1,000 7,382E-04 0,02572629 ! ectodermal gut morphogenesis GO:0048567 5 5 1,000 7,382E-04 0,02534231 GO:0007439|ectodermal gut development, ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 7,382E-04 0,02496963 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 1,000 7,382E-04 0,02460776 GO:0022011|myelination in the peripheral nervous system, ! DNA catabolic process, endonucleolytic GO:0000737 26 21 2,000 7,64E-04 0,0251027 ! regulation of lymphocyte differentiation GO:0045619 69 48 3,000 7,939E-04 0,02571837 ! regulation of intracellular transport GO:0032386 78 49 3,000 8,587E-04 0,02743045 ! interphase of mitotic cell cycle GO:0051329 156 86 4,000 9,199E-04 0,02898234 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 9,993E-04 0,03105853 ! positive regulation of cell migration GO:0030335 92 51 3,000 9,993E-04 0,03064442 ! myelination GO:0042552 35 23 2,000 1,004E-03 0,03039772 ! cellular iron ion homeostasis GO:0006879 37 23 2,000 1,004E-03 0,03000294 ! interphase GO:0051325 159 88 4,000 1,02E-03 0,03009161 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 1,000 1,101E-03 0,03205521 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 1,101E-03 0,03165452 ! mRNA stabilization GO:0048255 15 6 1,000 1,101E-03 0,03126373 GO:0043489|RNA stabilization, ! spinal cord dorsal/ventral patterning GO:0021513 6 6 1,000 1,101E-03 0,03088246 ! activation of MAPKKK activity GO:0000185 10 6 1,000 1,101E-03 0,03051038 ! ER overload response GO:0006983 7 6 1,000 1,101E-03 0,03014717 ! vascular smooth muscle contraction GO:0014829 10 6 1,000 1,101E-03 0,02979249 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 1,000 1,101E-03 0,02944607 ! spindle checkpoint GO:0031577 14 6 1,000 1,101E-03 0,02910761 ! astrocyte development GO:0014002 14 6 1,000 1,101E-03 0,02877684 ! Schwann cell development GO:0014044 14 6 1,000 1,101E-03 0,0284535 ! regulation of viral transcription GO:0046782 8 6 1,000 1,101E-03 0,02813735 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 1,000 1,101E-03 0,02782815 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 1,141E-03 0,02851642 ! regulation of mitosis GO:0007088 84 54 3,000 1,239E-03 0,03065103 GO:0051783|regulation of nuclear division, ! iron ion homeostasis GO:0055072 39 25 2,000 1,288E-03 0,03151445 ! regulation of chromosome organization GO:0033044 35 25 2,000 1,288E-03 0,03118272 ! positive regulation of cell motion GO:0051272 99 56 3,000 1,42E-03 0,03402548 ! regulation of binding GO:0051098 151 95 4,000 1,438E-03 0,03409249 ! negative regulation of protein kinase activity GO:0006469 99 57 3,000 1,517E-03 0,03560695 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 1,533E-03 0,03560686 ! negative regulation of cellular catabolic process GO:0031330 9 7 1,000 1,533E-03 0,0352508 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 1,000 1,533E-03 0,03490178 ! cerebral cortex cell migration GO:0021795 11 7 1,000 1,533E-03 0,0345596 ! microtubule bundle formation GO:0001578 8 7 1,000 1,533E-03 0,03422407 ! T-helper 1 type immune response GO:0042088 11 7 1,000 1,533E-03 0,033895 ! spinal cord patterning GO:0021511 7 7 1,000 1,533E-03 0,03357219 ! hemoglobin metabolic process GO:0020027 10 7 1,000 1,533E-03 0,03325547 ! regulation of defense response to virus by virus GO:0050690 16 7 1,000 1,533E-03 0,03294467 ! spinal cord motor neuron differentiation GO:0021522 9 7 1,000 1,533E-03 0,03263963 ! transcription from RNA polymerase I promoter GO:0006360 12 7 1,000 1,533E-03 0,03234018 ! negative regulation of kinase activity GO:0033673 100 58 3,000 1,619E-03 0,03384461 ! ensheathment of neurons GO:0007272 43 28 2,000 1,8E-03 0,0372949 GO:0008366|axon ensheathment, ! regulation of homeostatic process GO:0032844 105 60 3,000 1,836E-03 0,03769583 ! negative regulation of transferase activity GO:0051348 105 61 3,000 1,951E-03 0,03971708 ! telencephalon development GO:0021537 52 29 2,000 1,995E-03 0,04024705 ! cell proliferation in forebrain GO:0021846 10 8 1,000 2,032E-03 0,04063747 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 2,032E-03 0,04028714 ! induction of positive chemotaxis GO:0050930 14 8 1,000 2,032E-03 0,03994281 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 2,032E-03 0,03960431 ! smoothened signaling pathway GO:0007224 8 8 1,000 2,032E-03 0,0392715 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 1,000 2,032E-03 0,03894424 ! middle ear morphogenesis GO:0042474 9 8 1,000 2,032E-03 0,03862239 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 2,032E-03 0,03830581 ! astrocyte differentiation GO:0048708 16 8 1,000 2,032E-03 0,03799438 ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 2,032E-03 0,03768797 ! regulation of vascular permeability GO:0043114 12 8 1,000 2,032E-03 0,03738647 ! Schwann cell differentiation GO:0014037 17 8 1,000 2,032E-03 0,03708975 ! induction of an organ GO:0001759 11 8 1,000 2,032E-03 0,03679771 ! regulation of macrophage differentiation GO:0045649 14 8 1,000 2,032E-03 0,03651023 ! regulation of telomere maintenance GO:0032204 10 8 1,000 2,032E-03 0,0362272 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 2,032E-03 0,03594853 ! negative regulation of cell growth GO:0030308 106 62 3,000 2,072E-03 0,03637796 ! spindle organization GO:0007051 37 30 2,000 2,202E-03 0,03837651 ! negative regulation of cell size GO:0045792 108 64 3,000 2,329E-03 0,04026782 ! mammary gland development GO:0030879 57 31 2,000 2,423E-03 0,04158937 ! odontogenesis GO:0042476 50 31 2,000 2,423E-03 0,0412813 ! cell fate specification GO:0001708 37 31 2,000 2,423E-03 0,04097776 ! telencephalon cell migration GO:0022029 16 9 1,000 2,598E-03 0,04360807 ! lung alveolus development GO:0048286 17 9 1,000 2,598E-03 0,04329207 ! ventral spinal cord development GO:0021517 11 9 1,000 2,598E-03 0,04298062 ! substrate-bound cell migration GO:0006929 10 9 1,000 2,598E-03 0,04267361 ! motor axon guidance GO:0008045 14 9 1,000 2,598E-03 0,04237097 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 1,000 2,598E-03 0,04207258 ! negative regulation of lymphocyte differentiation GO:0045620 11 9 1,000 2,598E-03 0,04177836 ! localization within membrane GO:0051668 15 9 1,000 2,598E-03 0,04148824 ! peripheral nervous system development GO:0007422 53 32 2,000 2,657E-03 0,04214211 ! regulation of protein stability GO:0031647 48 32 2,000 2,657E-03 0,04185347 ! nucleus organization GO:0006997 49 33 2,000 2,904E-03 0,04543662 ! negative regulation of DNA binding GO:0043392 54 33 2,000 2,904E-03 0,04512961 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 3,165E-03 0,04885418 ! embryonic organ development GO:0048568 45 34 2,000 3,165E-03 0,04852849 ! pathogenesis GO:0009405 13 10 1,000 3,228E-03 0,04917459 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 1,000 3,228E-03 0,04885107 ! forebrain cell migration GO:0021885 17 10 1,000 3,228E-03 0,04853179 ! regulation of B cell differentiation GO:0045577 16 10 1,000 3,228E-03 0,04821665 ! cranial nerve development GO:0021545 12 10 1,000 3,228E-03 0,04790557 ! neuron fate specification GO:0048665 11 10 1,000 3,228E-03 0,04759848 ! blood vessel remodeling GO:0001974 21 10 1,000 3,228E-03 0,04729531 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 1,000 3,228E-03 0,04699597 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 3,228E-03 0,0467004 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 3,228E-03 0,04640852 ! regulation of bone resorption GO:0045124 24 10 1,000 3,228E-03 0,04612027 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 3,228E-03 0,04583558 ! nitric oxide mediated signal transduction GO:0007263 17 10 1,000 3,228E-03 0,04555438 ! positive regulation of viral reproduction GO:0048524 15 10 1,000 3,228E-03 0,04527661 ! embryonic gut development GO:0048566 11 10 1,000 3,228E-03 0,0450022 ! developmental induction GO:0031128 13 10 1,000 3,228E-03 0,0447311 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of action potential in neuron GO:0019228 54 35 2,000 3,44E-03 0,0473738 ! negative regulation of organelle organization GO:0010639 115 72 3,000 3,574E-03 0,04892821 ! regulation of hormone secretion GO:0046883 48 36 2,000 3,729E-03 0,05074652 ! negative regulation of binding GO:0051100 58 36 2,000 3,729E-03 0,05044801 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 3,923E-03 0,0527708 ! regulation of positive chemotaxis GO:0050926 17 11 1,000 3,923E-03 0,052464 GO:0050927|positive regulation of positive chemotaxis, ! detection of mechanical stimulus GO:0050982 15 11 1,000 3,923E-03 0,05216074 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 3,923E-03 0,05186096 ! negative regulation of proteolysis GO:0045861 16 11 1,000 3,923E-03 0,05156461 ! regulation of mRNA processing GO:0050684 18 11 1,000 3,923E-03 0,05127163 ! focal adhesion formation GO:0048041 24 11 1,000 3,923E-03 0,05098196 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 1,000 3,923E-03 0,05069555 ! vasoconstriction GO:0042310 15 11 1,000 3,923E-03 0,05041233 ! nucleosome positioning GO:0016584 13 11 1,000 3,923E-03 0,05013226 ! regulation of leukocyte migration GO:0002685 24 11 1,000 3,923E-03 0,04985529 ! digestive tract morphogenesis GO:0048546 15 11 1,000 3,923E-03 0,04958136 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! negative regulation of growth GO:0045926 123 75 3,000 4,139E-03 0,05201482 ! regulation of protein transport GO:0051223 114 76 3,000 4,339E-03 0,05424289 GO:0070201|regulation of establishment of protein localization, ! regulation of T cell proliferation GO:0042129 58 38 2,000 4,35E-03 0,05408321 ! regulation of DNA binding GO:0051101 119 77 3,000 4,547E-03 0,05622348 ! histone acetylation GO:0016573 23 12 1,000 4,681E-03 0,05757754 ! peptidyl-lysine modification GO:0018205 18 12 1,000 4,681E-03 0,05727128 ! regulation of mRNA stability GO:0043488 27 12 1,000 4,681E-03 0,05696825 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 4,681E-03 0,05666842 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 2,000 4,683E-03 0,05639181 ! cell growth GO:0016049 61 39 2,000 4,683E-03 0,05609811 ! induction of apoptosis by intracellular signals GO:0008629 67 40 2,000 5,031E-03 0,05995214 ! positive regulation of protein transport GO:0051222 55 40 2,000 5,031E-03 0,05964311 ! forebrain development GO:0030900 131 80 3,000 5,209E-03 0,06143452 ! glucose transport GO:0015758 52 41 2,000 5,394E-03 0,06329386 ! regulation of T cell differentiation GO:0045580 59 41 2,000 5,394E-03 0,06297257 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 1,000 5,501E-03 0,06390069 ! endocrine pancreas development GO:0031018 19 13 1,000 5,501E-03 0,06357958 ! cell differentiation in spinal cord GO:0021515 16 13 1,000 5,501E-03 0,06326168 ! response to hexose stimulus GO:0009746 19 13 1,000 5,501E-03 0,06294695 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! bone mineralization GO:0030282 15 13 1,000 5,501E-03 0,06263533 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 5,501E-03 0,06232678 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 5,501E-03 0,06202126 ! regulation of RNA stability GO:0043487 28 13 1,000 5,501E-03 0,06171871 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 1,000 5,501E-03 0,06141911 ! cellular component disassembly GO:0022411 64 42 2,000 5,772E-03 0,06413404 ! hexose transport GO:0008645 54 42 2,000 5,772E-03 0,0638257 GO:0015749|monosaccharide transport, ! activation of caspase activity GO:0006919 65 43 2,000 6,166E-03 0,06785452 ! response to insulin stimulus GO:0032868 63 43 2,000 6,166E-03 0,06753141 ! microtubule cytoskeleton organization GO:0000226 120 84 3,000 6,187E-03 0,06744426 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 6,381E-03 0,06923229 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 6,381E-03 0,06890726 ! cardiac muscle contraction GO:0060048 23 14 1,000 6,381E-03 0,06858526 ! limbic system development GO:0021761 25 14 1,000 6,381E-03 0,06826626 ! activation of MAPKK activity GO:0000186 21 14 1,000 6,381E-03 0,06795022 ! regulation of defense response to virus GO:0050688 24 14 1,000 6,381E-03 0,06763708 ! negative regulation of microtubule depolymerization GO:0007026 31 14 1,000 6,381E-03 0,06732682 GO:0031114|regulation of microtubule depolymerization, ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 1,000 6,381E-03 0,06701939 GO:0060675|ureteric bud morphogenesis, ! mRNA splice site selection GO:0006376 26 14 1,000 6,381E-03 0,06671476 ! regulation of erythrocyte differentiation GO:0045646 27 14 1,000 6,381E-03 0,06641288 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 6,381E-03 0,06611372 ! regulation of protein localization GO:0032880 132 85 3,000 6,45E-03 0,06652197 ! regulation of action potential GO:0001508 71 44 2,000 6,575E-03 0,0675157 ! skeletal muscle tissue development GO:0007519 123 87 3,000 6,997E-03 0,0715209 GO:0060538|skeletal muscle organ development, ! positive regulation of cell cycle GO:0045787 77 45 2,000 7,001E-03 0,07124716 ! vascular process in circulatory system GO:0003018 69 45 2,000 7,001E-03 0,0709333 ! protein amino acid autophosphorylation GO:0046777 80 45 2,000 7,001E-03 0,07062219 ! negative regulation of hormone secretion GO:0046888 20 15 1,000 7,321E-03 0,07353359 ! lipid phosphorylation GO:0046834 23 15 1,000 7,321E-03 0,07321388 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 1,000 7,321E-03 0,07289694 ! myoblast differentiation GO:0045445 27 15 1,000 7,321E-03 0,07258273 ! regulation of survival gene product expression GO:0045884 20 15 1,000 7,321E-03 0,07227122 ! cerebral cortex development GO:0021987 29 15 1,000 7,321E-03 0,07196236 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 7,321E-03 0,07165614 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 7,321E-03 0,07135251 ! biomineral formation GO:0031214 18 15 1,000 7,321E-03 0,07105145 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 1,000 7,321E-03 0,07075291 ! response to UV GO:0009411 75 46 2,000 7,442E-03 0,07161906 ! endothelial cell migration GO:0043542 22 16 1,000 8,32E-03 0,07973197 ! protein amino acid acetylation GO:0006473 28 16 1,000 8,32E-03 0,07940113 ! glial cell development GO:0021782 24 16 1,000 8,32E-03 0,07907303 ! nerve development GO:0021675 18 16 1,000 8,32E-03 0,07874762 ! positive regulation of caspase activity GO:0043280 72 48 2,000 8,373E-03 0,07892897 GO:0010952|positive regulation of peptidase activity, ! peptidyl-amino acid modification GO:0018193 147 93 3,000 8,819E-03 0,08278798 ! skeletal muscle fiber development GO:0048741 73 50 2,000 9,37E-03 0,08760562 ! positive regulation of hormone secretion GO:0046887 24 17 1,000 9,376E-03 0,08730451 ! cell-substrate junction assembly GO:0007044 39 17 1,000 9,376E-03 0,08695247 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 9,376E-03 0,08660327 ! actin filament bundle formation GO:0051017 26 17 1,000 9,376E-03 0,08625685 ! neuromuscular junction development GO:0007528 23 17 1,000 9,376E-03 0,0859132 ! negative regulation of protein catabolic process GO:0042177 26 17 1,000 9,376E-03 0,08557227 ! negative regulation of intracellular transport GO:0032387 29 17 1,000 9,376E-03 0,08523404 ! peptidyl-serine modification GO:0018209 27 17 1,000 9,376E-03 0,08489848 ! proximal/distal pattern formation GO:0009954 25 17 1,000 9,376E-03 0,08456554 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 9,376E-03 0,08423521 ! muscle fiber development GO:0048747 74 51 2,000 9,893E-03 0,08853803 ! regulation of protein catabolic process GO:0042176 77 51 2,000 9,893E-03 0,08819485 ! establishment of organelle localization GO:0051656 85 52 2,000 0,01043303 0,09264854 ! pancreas development GO:0031016 26 18 1,000 0,01048799 0,09277837 ! response to carbohydrate stimulus GO:0009743 24 18 1,000 0,01048799 0,0924229 ! heart process GO:0003015 27 18 1,000 0,01048799 0,09207014 GO:0060047|heart contraction, ! somitogenesis GO:0001756 24 18 1,000 0,01048799 0,09172006 ! gut development GO:0048565 26 18 1,000 0,01048799 0,09137264 ! skeletal system morphogenesis GO:0048705 78 53 2,000 0,0109897 0,09538226 ! cell projection assembly GO:0030031 76 53 2,000 0,0109897 0,09502368 ! DNA catabolic process GO:0006308 67 54 2,000 0,01156324 0,09960847 ! positive regulation of protein catabolic process GO:0045732 23 19 1,000 0,01165555 0,10002894 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 0,01165555 0,09965708 ! response to alkaloid GO:0043279 32 19 1,000 0,01165555 0,09928798 ! smooth muscle contraction GO:0006939 36 19 1,000 0,01165555 0,0989216 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 0,01165555 0,09855792 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 0,01165555 0,0981969 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 1,000 0,01165555 0,09783852 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 0,01165555 0,09748274 ! iron ion transport GO:0006826 37 20 1,000 0,01287738 0,1073115 ! hindlimb morphogenesis GO:0035137 32 20 1,000 0,01287738 0,10692409 ! spinal cord development GO:0021510 31 20 1,000 0,01287738 0,10653947 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 1,000 0,01287738 0,10615761 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 1,000 0,01287738 0,10577848 ! pallium development GO:0021543 38 20 1,000 0,01287738 0,10540204 ! positive regulation of locomotion GO:0040017 35 20 1,000 0,01287738 0,10502827 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of B cell activation GO:0050871 31 20 1,000 0,01287738 0,10465715 ! camera-type eye morphogenesis GO:0048593 34 20 1,000 0,01287738 0,10428864 ! carbohydrate transport GO:0008643 74 57 2,000 0,013386 0,10802733 ! camera-type eye development GO:0043010 88 57 2,000 0,013386 0,10764962 ! response to peptide hormone stimulus GO:0043434 84 57 2,000 0,013386 0,10727453 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 0,01415247 0,11302322 ! protein amino acid acylation GO:0043543 37 21 1,000 0,01415247 0,11263214 ! regulation of chemotaxis GO:0050920 36 21 1,000 0,01415247 0,11224375 ! dendrite development GO:0016358 35 21 1,000 0,01415247 0,11185803 ! ovarian follicle development GO:0001541 30 21 1,000 0,01415247 0,11147496 ! activation of pro-apoptotic gene products GO:0008633 36 21 1,000 0,01415247 0,1110945 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 0,01415247 0,11071662 ! regulation of insulin secretion GO:0050796 26 21 1,000 0,01415247 0,11034131 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 1,000 0,01415247 0,10996854 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 0,01415247 0,10959827 ! regulation of multi-organism process GO:0043900 32 21 1,000 0,01415247 0,10923049 ! protein import into nucleus, translocation GO:0000060 36 22 1,000 0,01547982 0,11907553 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 0,01547982 0,11867861 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 1,000 0,01547982 0,11828433 ! vasculogenesis GO:0001570 33 22 1,000 0,01547982 0,11789266 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 0,01547982 0,11750358 GO:0010810|regulation of cell-substrate adhesion, ! ureteric bud development GO:0001657 32 22 1,000 0,01547982 0,11711705 ! regulation of behavior GO:0050795 38 22 1,000 0,01547982 0,11673306 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 2,000 0,01676816 0,12603519 ! organelle localization GO:0051640 96 62 2,000 0,01676816 0,12562466 ! neuron fate commitment GO:0048663 32 23 1,000 0,01685843 0,12589084 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 0,01685843 0,12548343 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 0,01685843 0,12507864 ! vesicle targeting GO:0006903 32 23 1,000 0,01685843 0,12467646 ! regulation of viral reproduction GO:0050792 32 23 1,000 0,01685843 0,12427686 ! regulation of response to biotic stimulus GO:0002831 35 23 1,000 0,01685843 0,12387981 ! negative regulation of catabolic process GO:0009895 34 23 1,000 0,01685843 0,12348529 ! regulation of transcription factor activity GO:0051090 97 63 2,000 0,01749669 0,12775358 GO:0090046|regulation of transcription regulator activity, ! appendage morphogenesis GO:0035107 93 64 2,000 0,01824266 0,13277886 GO:0035108|limb morphogenesis, ! regulation of cellular catabolic process GO:0031329 36 24 1,000 0,01828731 0,13268398 ! regulation of interferon-gamma production GO:0032649 30 24 1,000 0,01828731 0,13226674 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 0,01828731 0,13185211 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 0,01828731 0,13144007 ! regulation of caspase activity GO:0043281 97 65 2,000 0,01900611 0,13618086 ! appendage development GO:0048736 94 65 2,000 0,01900611 0,13575794 GO:0060173|limb development, ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 2,000 0,01900611 0,13533764 ! regulation of peptide secretion GO:0002791 34 25 1,000 0,01976552 0,14031077 ! positive regulation of nuclear division GO:0051785 39 25 1,000 0,01976552 0,13987904 GO:0045840|positive regulation of mitosis, ! axon guidance GO:0007411 99 66 2,000 0,01978706 0,13960196 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 0,02058552 0,14479115 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 0,02129208 0,14930422 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 0,02129208 0,14885041 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 1,000 0,02129208 0,14839935 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 0,02129208 0,14795101 ! intracellular protein transmembrane transport GO:0065002 102 68 2,000 0,02140152 0,14826351 ! activation of protein kinase activity GO:0032147 102 69 2,000 0,02223504 0,15357534 ! positive regulation of ligase activity GO:0051351 99 69 2,000 0,02223504 0,15311554 ! negative regulation of transcription regulator activity GO:0090048 47 27 1,000 0,02286606 0,15699089 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of protein transport GO:0051224 49 27 1,000 0,02286606 0,15652366 ! eye development GO:0001654 111 70 2,000 0,0230861 0,15756091 ! regulation of catabolic process GO:0009894 106 70 2,000 0,0230861 0,15709476 ! phosphoinositide-mediated signaling GO:0048015 109 71 2,000 0,02395469 0,16252447 ! cell junction assembly GO:0034329 56 28 1,000 0,02448654 0,16564424 ! mesoderm formation GO:0001707 46 28 1,000 0,02448654 0,16515848 ! positive regulation of multicellular organism growth GO:0040018 38 28 1,000 0,02448654 0,16467556 ! positive regulation of catabolic process GO:0009896 40 28 1,000 0,02448654 0,16419546 ! regulation of peptidase activity GO:0052547 106 72 2,000 0,02484082 0,16608685 ! response to hypoxia GO:0001666 132 72 2,000 0,02484082 0,16560543 ! negative regulation of transport GO:0051051 116 73 2,000 0,02574445 0,17113366 ! mitochondrion organization GO:0007005 104 73 2,000 0,02574445 0,17064048 ! ovulation cycle process GO:0022602 41 29 1,000 0,02615259 0,17284758 ! protein targeting to membrane GO:0006612 53 29 1,000 0,02615259 0,17235232 ! regulation of axonogenesis GO:0050770 51 29 1,000 0,02615259 0,17185988 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 0,02615259 0,17137025 ! formation of primary germ layer GO:0001704 48 29 1,000 0,02615259 0,17088341 ! eye morphogenesis GO:0048592 51 29 1,000 0,02615259 0,17039932 ! tissue homeostasis GO:0001894 42 29 1,000 0,02615259 0,16991796 GO:0048871|multicellular organismal homeostasis, ! response to oxygen levels GO:0070482 137 74 2,000 0,0266656 0,17276302 ! protein import into nucleus GO:0006606 118 74 2,000 0,0266656 0,17227773 ! cellular response to hormone stimulus GO:0032870 109 74 2,000 0,0266656 0,17179516 ! nuclear import GO:0051170 121 75 2,000 0,02760422 0,17734556 ! embryonic skeletal system morphogenesis GO:0048704 42 30 1,000 0,02786331 0,17851148 ! spliceosome assembly GO:0000245 49 30 1,000 0,02786331 0,17801561 ! ovulation cycle GO:0042698 43 30 1,000 0,02786331 0,17752249 ! hindbrain development GO:0030902 45 30 1,000 0,02786331 0,1770321 ! regulation of microtubule-based process GO:0032886 58 30 1,000 0,02786331 0,17654441 ! establishment of vesicle localization GO:0051650 45 30 1,000 0,02786331 0,1760594 ! regulation of cell morphogenesis GO:0022604 140 76 2,000 0,02856031 0,17996908 ! negative regulation of secretion GO:0051048 49 31 1,000 0,02961782 0,18612288 ! glial cell differentiation GO:0010001 55 31 1,000 0,02961782 0,18561574 ! segmentation GO:0035282 41 31 1,000 0,02961782 0,18511135 ! mesoderm morphogenesis GO:0048332 49 31 1,000 0,02961782 0,18460969 ! metanephros development GO:0001656 58 31 1,000 0,02961782 0,18411074 ! response to mechanical stimulus GO:0009612 43 31 1,000 0,02961782 0,18361449 ! mitotic sister chromatid segregation GO:0000070 45 32 1,000 0,03141522 0,19423387 ! meiosis I GO:0007127 52 32 1,000 0,03141522 0,19371314 ! regulation of synaptic plasticity GO:0048167 52 32 1,000 0,03141522 0,19319519 ! calcium-mediated signaling GO:0019722 50 32 1,000 0,03141522 0,19268 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 0,03141522 0,19216755 ! vesicle localization GO:0051648 47 32 1,000 0,03141522 0,19165782 ! protein localization in nucleus GO:0034504 133 80 2,000 0,03255868 0,19810839 ! negative regulation of cell adhesion GO:0007162 67 33 1,000 0,03325465 0,20180923 ! sister chromatid segregation GO:0000819 46 33 1,000 0,03325465 0,20127815 ! ear morphogenesis GO:0042471 42 33 1,000 0,03325465 0,20074986 ! cell junction organization GO:0034330 63 33 1,000 0,03325465 0,20022434 ! carbohydrate homeostasis GO:0033500 39 33 1,000 0,03325465 0,19970156 GO:0042593|glucose homeostasis, ! female gonad development GO:0008585 49 33 1,000 0,03325465 0,1991815 ! regulation of proteolysis GO:0030162 50 33 1,000 0,03325465 0,19866415 ! cytokinesis GO:0000910 52 33 1,000 0,03325465 0,19814948 ! mRNA transport GO:0051028 121 81 2,000 0,0336016 0,19969945 ! ossification GO:0001503 134 82 2,000 0,03466177 0,20546926 GO:0060348|bone development, ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 0,03513526 0,20774062 ! regulation of neuron projection development GO:0010975 63 34 1,000 0,03513526 0,20720795 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 1,000 0,03513526 0,206678 ! dorsal/ventral pattern formation GO:0009953 44 34 1,000 0,03513526 0,20615076 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 1,000 0,03513526 0,20562621 ! regulation of cell adhesion GO:0030155 159 83 2,000 0,03573914 0,20862948 ! glycogen metabolic process GO:0005977 48 35 1,000 0,0370562 0,21577028 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,0370562 0,21522541 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of MAP kinase activity GO:0043406 121 85 2,000 0,03794526 0,21983398 ! transcription initiation GO:0006352 118 85 2,000 0,03794526 0,21928163 ! regulation of membrane potential GO:0042391 128 85 2,000 0,03794526 0,21873205 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,03901664 0,22434567 GO:0090047|positive regulation of transcription regulator activity, ! tissue remodeling GO:0048771 62 36 1,000 0,03901664 0,2237862 ! neural tube development GO:0021915 50 36 1,000 0,03901664 0,22322952 ! development of primary female sexual characteristics GO:0046545 52 36 1,000 0,03901664 0,2226756 GO:0046660|female sex differentiation, ! glucan metabolic process GO:0044042 49 36 1,000 0,03901664 0,22212442 GO:0006073|cellular glucan metabolic process, ! learning GO:0007612 67 37 1,000 0,04101575 0,23292895 ! amino acid activation GO:0043038 52 37 1,000 0,04101575 0,23235524 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! establishment of RNA localization GO:0051236 128 88 2,000 0,04138205 0,23385431 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 2,000 0,04138205 0,23328114 ! regulation of T cell activation GO:0050863 128 89 2,000 0,04256142 0,23934295 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,04272866 0,23969738 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,04272866 0,23911418 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,04272866 0,2385338 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,04272866 0,23795624 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,04272866 0,23738147 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,04272866 0,23680946 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,04272866 0,23624021 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,04272866 0,23567369 ! sleep GO:0030431 11 5 0,000 0,04272866 0,23510987 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,04272866 0,23454875 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,04272866 0,2339903 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,04272866 0,23343451 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,04272866 0,23288134 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 6 5 0,000 0,04272866 0,2323308 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,04272866 0,23178285 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,04272866 0,23123748 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,04272866 0,23069467 ! cobalt ion transport GO:0006824 9 5 0,000 0,04272866 0,2301544 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,04272866 0,22961665 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,04272866 0,22908142 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,04272866 0,22854867 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,04272866 0,22801839 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,04272866 0,22749057 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,04272866 0,22696519 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,04272866 0,22644223 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,04272866 0,22592167 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,04272866 0,2254035 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,04272866 0,22488771 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,04272866 0,22437426 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,04272866 0,22386316 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,04272866 0,22335438 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,04272866 0,22284791 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,04272866 0,22234373 ! malate metabolic process GO:0006108 7 5 0,000 0,04272866 0,22184182 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,04272866 0,22134218 ! behavioral response to pain GO:0048266 7 5 0,000 0,04272866 0,22084478 ! clathrin coat assembly GO:0048268 11 5 0,000 0,04272866 0,22034961 ! phototransduction, visible light GO:0007603 6 5 0,000 0,04272866 0,21985666 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,04272866 0,21936591 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! mating behavior GO:0007617 6 5 0,000 0,04272866 0,21887734 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,04272866 0,21839095 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,04272866 0,21790671 ! rhythmic behavior GO:0007622 12 5 0,000 0,04272866 0,21742462 ! copulation GO:0007620 7 5 0,000 0,04272866 0,21694465 ! glial cell fate commitment GO:0021781 12 5 0,000 0,04272866 0,2164668 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,04272866 0,21599105 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,04272866 0,21551738 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,04272866 0,21504579 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,04272866 0,21457626 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,04272866 0,21410877 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,04272866 0,21364332 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,04272866 0,21317989 ! response to protozoan GO:0001562 9 5 0,000 0,04272866 0,21271846 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,04272866 0,21225902 ! endochondral ossification GO:0001958 12 5 0,000 0,04272866 0,21180157 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,04272866 0,21134608 ! parathyroid gland development GO:0060017 8 5 0,000 0,04272866 0,21089255 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,04272866 0,21044096 ! anagen GO:0042640 6 5 0,000 0,04272866 0,2099913 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,04272866 0,20954356 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,04272866 0,20909772 ! nuclear migration GO:0007097 10 5 0,000 0,04272866 0,20865377 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,04272866 0,20821171 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,04272866 0,20777152 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,04272866 0,20733318 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,04272866 0,20689669 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,04272866 0,20646203 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,04272866 0,2060292 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,04272866 0,20559817 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,04272866 0,20516895 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,04272866 0,20474152 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,04272866 0,20431586 ! ovulation GO:0030728 6 5 0,000 0,04272866 0,20389197 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,04272866 0,20346983 GO:0033135|regulation of peptidyl-serine phosphorylation, ! valine metabolic process GO:0006573 8 5 0,000 0,04272866 0,20304944 ! response to pH GO:0009268 9 5 0,000 0,04272866 0,20263078 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,04272866 0,20221384 ! proline biosynthetic process GO:0006561 6 5 0,000 0,04272866 0,20179862 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,04272866 0,2013851 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,04272866 0,20097327 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,04272866 0,20056312 ! polyol catabolic process GO:0046174 7 5 0,000 0,04272866 0,20015464 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,04272866 0,19974782 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,04272866 0,19934265 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,04272866 0,19893912 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,04272866 0,19853723 ! nerve growth factor processing GO:0032455 7 5 0,000 0,04272866 0,19813695 ! urea metabolic process GO:0019627 6 5 0,000 0,04272866 0,19773828 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,04272866 0,19734122 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,04272866 0,19694575 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,04272866 0,19655185 ! neutrophil activation GO:0042119 5 5 0,000 0,04272866 0,19615954 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,04272866 0,19576878 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,04272866 0,19537958 ! response to food GO:0032094 5 5 0,000 0,04272866 0,19499192 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,04272866 0,1946058 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,04272866 0,1942212 ! forebrain neuron development GO:0021884 7 5 0,000 0,04272866 0,19383812 ! melanosome organization GO:0032438 7 5 0,000 0,04272866 0,19345655 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,04272866 0,19307648 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,04272866 0,1926979 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,04272866 0,1923208 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,04272866 0,19194517 ! nucleoside transport GO:0015858 6 5 0,000 0,04272866 0,19157101 ! nucleoside salvage GO:0043174 7 5 0,000 0,04272866 0,1911983 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,04272866 0,19082704 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,04272866 0,19045722 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,04272866 0,19008883 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,04272866 0,18972187 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,04272866 0,18935631 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,04272866 0,18899217 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,04272866 0,18862942 ! depyrimidination GO:0045008 8 5 0,000 0,04272866 0,18826806 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,04272866 0,18790808 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,04272866 0,18754948 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,04272866 0,18719224 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,04272866 0,18683636 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,04272866 0,18648184 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,04272866 0,18612865 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,04272866 0,1857768 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,04272866 0,18542628 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,04272866 0,18507708 ! monocyte differentiation GO:0030224 8 5 0,000 0,04272866 0,18472919 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,04272866 0,1843826 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,04272866 0,18403732 ! centrosome duplication GO:0051298 5 5 0,000 0,04272866 0,18369332 ! response to UV-C GO:0010225 6 5 0,000 0,04272866 0,18335061 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,04272866 0,18300918 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,04272866 0,18266901 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,04272866 0,18233011 ! regulation of dendrite development GO:0050773 12 5 0,000 0,04272866 0,18199246 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,04272866 0,18165606 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,04272866 0,1813209 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,04272866 0,18098698 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,04272866 0,18065428 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,04272866 0,1803228 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,04272866 0,17999254 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,04272866 0,17966349 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,04272866 0,17933563 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,04272866 0,17900898 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,04272866 0,1786835 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,04272866 0,17835921 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,04272866 0,1780361 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,04272866 0,17771415 ! neural tube patterning GO:0021532 6 5 0,000 0,04272866 0,17739337 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,04272866 0,17707374 ! histone demethylation GO:0016577 9 5 0,000 0,04272866 0,17675527 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,04272866 0,17643793 ! regulation of sterol transport GO:0032371 7 5 0,000 0,04272866 0,17612173 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,04272866 0,17580667 ! enteric nervous system development GO:0048484 8 5 0,000 0,04272866 0,17549273 ! establishment of planar polarity GO:0001736 6 5 0,000 0,04272866 0,17517991 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,04272866 0,1748682 ! muscle cell proliferation GO:0033002 8 5 0,000 0,04272866 0,1745576 ! transcription termination GO:0006353 8 5 0,000 0,04272866 0,1742481 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,04272866 0,17393969 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,04272866 0,17363238 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,04272866 0,17332615 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,04272866 0,173021 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,04272866 0,17271692 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,04272866 0,17241391 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,04272866 0,17211196 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,04272866 0,17181106 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,04272866 0,17151122 ! apical protein localization GO:0045176 6 5 0,000 0,04272866 0,17121242 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,04272866 0,17091466 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,04272866 0,17061793 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,04272866 0,17032223 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,04272866 0,17002756 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,04272866 0,1697339 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,04272866 0,16944125 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,04272866 0,16914962 ! glial cell migration GO:0008347 10 5 0,000 0,04272866 0,16885898 ! determination of adult lifespan GO:0008340 8 5 0,000 0,04272866 0,16856934 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,04272866 0,1682807 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,04272866 0,16799304 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,04272866 0,16770636 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,04272866 0,16742066 ! neural plate development GO:0001840 6 5 0,000 0,04272866 0,16713593 ! regulation of sensory perception GO:0051931 6 5 0,000 0,04272866 0,16685217 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,04272866 0,16656937 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,04272866 0,16628753 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,04272866 0,16600663 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,04272866 0,16572669 ! sensory cilium assembly GO:0035058 6 5 0,000 0,04272866 0,16544769 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,04272866 0,16516963 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,04272866 0,1648925 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,04272866 0,16461629 ! spindle assembly GO:0051225 5 5 0,000 0,04272866 0,16434102 ! receptor biosynthetic process GO:0032800 6 5 0,000 0,04272866 0,16406666 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,04272866 0,16379321 ! organ regeneration GO:0031100 7 5 0,000 0,04272866 0,16352068 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,04272866 0,16324905 ! carnitine metabolic process GO:0009437 5 5 0,000 0,04272866 0,16297832 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,04272866 0,16270849 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,04272866 0,16243955 GO:0055081|anion homeostasis, ! gliogenesis GO:0042063 71 38 1,000 0,04305273 0,16340144 ! phagocytosis GO:0006909 60 38 1,000 0,04305273 0,16313224 ! pigmentation GO:0043473 74 38 1,000 0,04305273 0,16286393 ! RNA localization GO:0006403 135 91 2,000 0,04497043 0,16983905 ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 0,04512677 0,17015011 ! chromatin remodeling GO:0006338 68 39 1,000 0,04512677 0,16987163 ! developmental growth GO:0048589 62 39 1,000 0,04512677 0,16959406 ! synapse organization GO:0050808 55 39 1,000 0,04512677 0,1693174 ! regulation of tube size GO:0035150 60 40 1,000 0,04723708 0,17694673 GO:0050880|regulation of blood vessel size, ! positive regulation of response to external stimulus GO:0032103 65 40 1,000 0,04723708 0,17665901 ! detection of stimulus involved in sensory perception GO:0050906 50 40 1,000 0,04723708 0,17637223 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 0,04723708 0,17608637 ! energy reserve metabolic process GO:0006112 59 41 1,000 0,0493829 0,18378748 ! striated muscle contraction GO:0006941 62 41 1,000 0,0493829 0,18349057 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,0493829 0,18319462 ! regulation of JNK cascade GO:0046328 58 41 1,000 0,0493829 0,18289962 ! angiogenesis GO:0001525 149 95 2,000 0,04998737 0,18484077 ! tRNA transcription GO:0009304 11 6 0,000 0,05105419 0,18848257 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,05105419 0,18818051 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,05105419 0,18787942 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,05105419 0,1875793 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,05105419 0,18728013 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,05105419 0,18698191 ! regulation of helicase activity GO:0051095 11 6 0,000 0,05105419 0,18668464 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,05105419 0,18638832 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,05105419 0,18609293 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,05105419 0,18579848 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,05105419 0,18550496 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,05105419 0,18521237 ! prostate gland development GO:0030850 9 6 0,000 0,05105419 0,18492069 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,05105419 0,18462994 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,05105419 0,1843401 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,05105419 0,18405116 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,05105419 0,18376313 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,05105419 0,183476 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,05105419 0,18318977 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,05105419 0,18290442 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,05105419 0,18261997 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! neuron adhesion GO:0007158 9 6 0,000 0,05105419 0,1823364 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,05105419 0,18205371 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,05105419 0,18177189 ! signal peptide processing GO:0006465 8 6 0,000 0,05105419 0,18149094 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,05105419 0,18121087 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,05105419 0,18093165 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,05105419 0,18065329 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,05105419 0,18037579 ! opsonization GO:0008228 8 6 0,000 0,05105419 0,18009914 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,05105419 0,17982334 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,05105419 0,17954838 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,05105419 0,17927426 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,05105419 0,17900098 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,05105419 0,17872852 ! photoreceptor cell development GO:0042461 10 6 0,000 0,05105419 0,1784569 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,05105419 0,1781861 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,05105419 0,17791612 ! mechanosensory behavior GO:0007638 8 6 0,000 0,05105419 0,17764696 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,05105419 0,17737861 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,05105419 0,17711107 ! response to interferon-gamma GO:0034341 12 6 0,000 0,05105419 0,17684434 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,05105419 0,17657841 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,05105419 0,17631327 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,05105419 0,17604894 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,05105419 0,17578539 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,05105419 0,17552263 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,05105419 0,17526066 ! thymic T cell selection GO:0045061 12 6 0,000 0,05105419 0,17499946 ! protein lipoylation GO:0009249 10 6 0,000 0,05105419 0,17473905 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,05105419 0,17447941 ! pigment granule organization GO:0048753 11 6 0,000 0,05105419 0,17422053 ! drug transport GO:0015893 6 6 0,000 0,05105419 0,17396243 ! cysteine metabolic process GO:0006534 7 6 0,000 0,05105419 0,17370509 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,05105419 0,17344851 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,05105419 0,17319269 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,05105419 0,17293761 ! histidine metabolic process GO:0006547 6 6 0,000 0,05105419 0,17268329 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,05105419 0,17242972 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,05105419 0,17217689 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,05105419 0,1719248 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,05105419 0,17167345 ! adenohypophysis development GO:0021984 10 6 0,000 0,05105419 0,17142283 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,05105419 0,17117295 ! hyperosmotic response GO:0006972 8 6 0,000 0,05105419 0,17092379 ! microtubule nucleation GO:0007020 10 6 0,000 0,05105419 0,17067535 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,05105419 0,17042764 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,05105419 0,17018064 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,05105419 0,16993436 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,05105419 0,16968879 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 0,05105419 0,16944393 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,05105419 0,16919977 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,05105419 0,16895632 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,05105419 0,16871356 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,05105419 0,16847151 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,05105419 0,16823014 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,05105419 0,16798947 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,05105419 0,16774949 ! neuron apoptosis GO:0051402 8 6 0,000 0,05105419 0,16751019 ! organic alcohol transport GO:0015850 9 6 0,000 0,05105419 0,16727157 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,05105419 0,16703363 ! T cell mediated immunity GO:0002456 12 6 0,000 0,05105419 0,16679636 ! male sex determination GO:0030238 9 6 0,000 0,05105419 0,16655977 ! carnitine transport GO:0015879 8 6 0,000 0,05105419 0,16632385 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,05105419 0,1660886 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,05105419 0,16585401 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,05105419 0,16562009 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,05105419 0,16538682 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,05105419 0,16515421 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,05105419 0,16492225 ! parturition GO:0007567 12 6 0,000 0,05105419 0,16469094 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,05105419 0,16446028 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,05105419 0,16423027 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,05105419 0,16400089 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,05105419 0,16377216 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,05105419 0,16354407 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,05105419 0,16331661 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,05105419 0,16308978 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,05105419 0,16286358 ! macrophage differentiation GO:0030225 10 6 0,000 0,05105419 0,16263801 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,05105419 0,16241306 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,05105419 0,16218873 ! interaction with symbiont GO:0051702 8 6 0,000 0,05105419 0,16196502 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,05105419 0,16174193 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,05105419 0,16151945 ! eating behavior GO:0042755 6 6 0,000 0,05105419 0,16129758 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,05105419 0,16107632 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,05105419 0,16085567 ! response to copper ion GO:0046688 9 6 0,000 0,05105419 0,16063562 ! DNA topological change GO:0006265 8 6 0,000 0,05105419 0,16041618 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,05105419 0,16019733 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,05105419 0,15997907 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,05105419 0,15976142 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,05105419 0,15954435 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,05105419 0,15932787 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,05105419 0,15911198 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,05105419 0,15889667 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,05105419 0,15868195 ! gas homeostasis GO:0033483 11 6 0,000 0,05105419 0,1584678 ! hair follicle maturation GO:0048820 7 6 0,000 0,05105419 0,15825423 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,05105419 0,15804124 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,05105419 0,15782882 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,05105419 0,15761697 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,05105419 0,15740568 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,05105419 0,15719497 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,05105419 0,15698481 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,05105419 0,15677522 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,05105419 0,15656619 ! histone ubiquitination GO:0016574 7 6 0,000 0,05105419 0,15635771 ! regulation of meiosis GO:0040020 10 6 0,000 0,05105419 0,15614979 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,05105419 0,15594242 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,05105419 0,1557356 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,05105419 0,15552933 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,05105419 0,1553236 ! membrane to membrane docking GO:0022614 12 6 0,000 0,05105419 0,15511842 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,05105419 0,15491377 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,05105419 0,15470967 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,05105419 0,15450611 ! receptor internalization GO:0031623 9 6 0,000 0,05105419 0,15430308 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,05105419 0,15410058 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,05105419 0,15389861 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,05105419 0,15369717 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,05105419 0,15349626 ! protein deubiquitination GO:0016579 8 6 0,000 0,05105419 0,15329588 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,05105419 0,15309601 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,05105419 0,15289667 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,05105419 0,15269784 ! axonal fasciculation GO:0007413 9 6 0,000 0,05105419 0,15249953 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,05105419 0,15230174 ! thiamin metabolic process GO:0006772 6 6 0,000 0,05105419 0,15210446 ! midbrain development GO:0030901 6 6 0,000 0,05105419 0,15190769 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,05105419 0,15171142 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,05105419 0,15151567 GO:0045625|regulation of T-helper 1 cell differentiation, ! progesterone metabolic process GO:0042448 8 6 0,000 0,05105419 0,15132041 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,05105419 0,15112566 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,05105419 0,15093141 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,05105419 0,15073766 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,05105419 0,15054441 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,05105419 0,15035165 ! adult feeding behavior GO:0008343 6 6 0,000 0,05105419 0,15015939 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,05105419 0,14996761 ! blastocyst growth GO:0001832 15 6 0,000 0,05105419 0,14977633 ! pigment granule transport GO:0051904 12 6 0,000 0,05105419 0,14958553 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,05105419 0,14939522 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,05105419 0,14920539 ! catecholamine transport GO:0051937 7 6 0,000 0,05105419 0,14901604 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,05105419 0,14882717 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,05105419 0,14863879 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,05105419 0,14845087 ! protein prenylation GO:0018342 10 6 0,000 0,05105419 0,14826344 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,05105419 0,14807647 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,05105419 0,14788998 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,05105419 0,14770395 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,05105419 0,14751839 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 2,000 0,05128259 0,14799241 ! protein maturation GO:0051604 129 96 2,000 0,05128259 0,14780695 ! response to light stimulus GO:0009416 153 96 2,000 0,05128259 0,14762196 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 1,000 0,05156344 0,14824488 ! branching morphogenesis of a tube GO:0048754 72 42 1,000 0,05156344 0,14805981 ! embryonic skeletal system development GO:0048706 56 42 1,000 0,05156344 0,1478752 ! regulation of cell shape GO:0008360 78 42 1,000 0,05156344 0,14769104 ! positive regulation of binding GO:0051099 59 43 1,000 0,05377795 0,1538424 ! epithelial tube morphogenesis GO:0060562 65 43 1,000 0,05377795 0,15365129 ! protein import GO:0017038 156 99 2,000 0,0552652 0,15770467 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 2,000 0,0552652 0,15750924 ! regulation of cell projection organization GO:0031344 83 44 1,000 0,05602569 0,15947907 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 1,000 0,05602569 0,15928194 ! ribonucleoprotein complex assembly GO:0022618 70 44 1,000 0,05602569 0,15908529 ! detection of abiotic stimulus GO:0009582 58 44 1,000 0,05602569 0,15888913 ! protein localization in organelle GO:0033365 161 100 2,000 0,05662476 0,16039033 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,05930778 0,1677834 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,05930778 0,16757727 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,05930778 0,16737166 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,05930778 0,16716654 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,05930778 0,16696193 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,05930778 0,16675782 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,05930778 0,16655421 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,05930778 0,1663511 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,05930778 0,16614848 ! reproductive behavior GO:0019098 12 7 0,000 0,05930778 0,16594635 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,05930778 0,16574472 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,05930778 0,16554357 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,05930778 0,16534291 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,05930778 0,16514274 ! oligopeptide transport GO:0006857 11 7 0,000 0,05930778 0,16494305 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,05930778 0,16474384 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,05930778 0,16454512 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,05930778 0,16434687 ! RNA methylation GO:0001510 11 7 0,000 0,05930778 0,1641491 ! pericardium development GO:0060039 8 7 0,000 0,05930778 0,1639518 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,05930778 0,16375498 ! fibril organization GO:0043206 13 7 0,000 0,05930778 0,16355863 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,05930778 0,16336276 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,05930778 0,16316735 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,05930778 0,1629724 ! lipoprotein transport GO:0042953 9 7 0,000 0,05930778 0,16277792 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,05930778 0,16258391 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,05930778 0,16239036 ! estrogen metabolic process GO:0008210 14 7 0,000 0,05930778 0,16219727 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,05930778 0,16200463 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,05930778 0,16181246 ! chemosensory behavior GO:0007635 9 7 0,000 0,05930778 0,16162074 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,05930778 0,16142947 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,05930778 0,16123865 ! leukocyte degranulation GO:0043299 10 7 0,000 0,05930778 0,16104829 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,05930778 0,16085837 ! reflex GO:0060004 12 7 0,000 0,05930778 0,16066891 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,05930778 0,16047988 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,05930778 0,16029131 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,05930778 0,16010317 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,05930778 0,15991548 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,05930778 0,15972822 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,05930778 0,1595414 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,05930778 0,15935502 ! adrenal gland development GO:0030325 17 7 0,000 0,05930778 0,15916908 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,05930778 0,15898357 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,05930778 0,15879849 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,05930778 0,15861384 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,05930778 0,15842962 ! endosome organization GO:0007032 10 7 0,000 0,05930778 0,15824582 ! thyroid hormone generation GO:0006590 11 7 0,000 0,05930778 0,15806246 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,05930778 0,15787951 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,05930778 0,157697 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,05930778 0,1575149 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,05930778 0,15733322 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,05930778 0,15715196 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,05930778 0,15697112 ! galactose metabolic process GO:0006012 10 7 0,000 0,05930778 0,15679069 ! vesicle fusion GO:0006906 15 7 0,000 0,05930778 0,15661068 ! intracellular pH reduction GO:0051452 10 7 0,000 0,05930778 0,15643108 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,05930778 0,15625189 ! organ growth GO:0035265 11 7 0,000 0,05930778 0,15607311 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,05930778 0,15589474 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,05930778 0,15571678 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,05930778 0,15553923 ! retinol metabolic process GO:0042572 9 7 0,000 0,05930778 0,15536207 ! behavioral fear response GO:0001662 13 7 0,000 0,05930778 0,15518533 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,05930778 0,15500898 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,05930778 0,15483303 ! rRNA modification GO:0000154 12 7 0,000 0,05930778 0,15465748 ! protein heterooligomerization GO:0051291 10 7 0,000 0,05930778 0,15448233 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,05930778 0,15430758 ! response to UV-B GO:0010224 11 7 0,000 0,05930778 0,15413322 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,05930778 0,15395926 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,05930778 0,15378568 ! intermediate filament organization GO:0045109 11 7 0,000 0,05930778 0,1536125 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,05930778 0,15343971 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,05930778 0,1532673 ! fibrinolysis GO:0042730 9 7 0,000 0,05930778 0,15309529 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,05930778 0,15292366 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,05930778 0,15275241 ! B cell lineage commitment GO:0002326 17 7 0,000 0,05930778 0,15258154 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,05930778 0,15241106 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,05930778 0,15224096 ! response to tropane GO:0014073 13 7 0,000 0,05930778 0,15207124 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,05930778 0,15190189 ! melanosome localization GO:0032400 10 7 0,000 0,05930778 0,15173293 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,05930778 0,15156433 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,05930778 0,15139612 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,05930778 0,15122827 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,05930778 0,1510608 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,05930778 0,1508937 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,05930778 0,15072696 ! mast cell activation GO:0045576 9 7 0,000 0,05930778 0,1505606 ! multicellular organismal aging GO:0010259 11 7 0,000 0,05930778 0,1503946 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,05930778 0,15022897 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,05930778 0,1500637 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,05930778 0,14989879 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,05930778 0,14973425 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,05930778 0,14957007 ! T cell lineage commitment GO:0002360 12 7 0,000 0,05930778 0,14940624 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,05930778 0,14924278 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,05930778 0,14907967 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,05930778 0,14891692 ! regulation of lipid transport GO:0032368 13 7 0,000 0,05930778 0,14875453 ! response to tumor cell GO:0002347 12 7 0,000 0,05930778 0,14859248 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,05930778 0,1484308 ! neuroblast proliferation GO:0007405 13 7 0,000 0,05930778 0,14826946 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,05930778 0,14810847 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,05930778 0,14794783 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,05930778 0,14778754 ! diuresis GO:0030146 12 7 0,000 0,05930778 0,1476276 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,05930778 0,147468 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,05930778 0,14730875 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,05930778 0,14714984 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,05930778 0,14699127 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,05930778 0,14683305 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,05930778 0,14667516 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,05930778 0,14651762 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,05930778 0,14636041 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,05930778 0,14620354 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,05930778 0,146047 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,05930778 0,1458908 ! lymph node development GO:0048535 9 7 0,000 0,05930778 0,14573494 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,05930778 0,1455794 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,05930778 0,1454242 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,05930778 0,14526933 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,05930778 0,14511479 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,05930778 0,14496057 ! ATP catabolic process GO:0006200 10 7 0,000 0,05930778 0,14480669 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,05930778 0,14465313 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,05930778 0,14449989 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,05930778 0,14434698 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,05930778 0,1441944 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,05930778 0,14404213 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,05930778 0,14389019 ! muscle adaptation GO:0043500 12 7 0,000 0,05930778 0,14373857 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,05930778 0,14358726 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,05930778 0,14343628 ! retina homeostasis GO:0001895 9 7 0,000 0,05930778 0,14328561 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,05930778 0,14313526 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,05930778 0,14298522 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,05930778 0,1428355 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,05930778 0,14268609 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,05930778 0,14253699 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,05930778 0,14238821 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,05930778 0,14223973 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 0,06061791 0,1452304 ! histone modification GO:0016570 68 46 1,000 0,06061791 0,14507928 ! covalent chromatin modification GO:0016569 75 47 1,000 0,06296094 0,15053032 ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 0,06533432 0,1560425 ! gastrulation GO:0007369 73 48 1,000 0,06533432 0,15588063 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,06749006 0,16085713 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,06749006 0,16069061 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,06749006 0,16052443 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,06749006 0,1603586 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,06749006 0,16019311 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,06749006 0,16002797 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,06749006 0,15986316 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,06749006 0,15969869 ! phosphate transport GO:0006817 10 8 0,000 0,06749006 0,15953456 ! N-glycan processing GO:0006491 12 8 0,000 0,06749006 0,15937077 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,06749006 0,15920731 ! UTP metabolic process GO:0046051 8 8 0,000 0,06749006 0,15904419 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,06749006 0,1588814 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,06749006 0,15871894 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,06749006 0,15855682 ! succinate metabolic process GO:0006105 14 8 0,000 0,06749006 0,15839503 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,06749006 0,15823357 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,06749006 0,15807243 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,06749006 0,15791163 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,06749006 0,15775115 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,06749006 0,15759099 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,06749006 0,15743116 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,06749006 0,15727166 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,06749006 0,15711248 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,06749006 0,15695362 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,06749006 0,15679508 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,06749006 0,15663686 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,06749006 0,15647896 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,06749006 0,15632138 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,06749006 0,15616411 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,06749006 0,15600716 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,06749006 0,15585053 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,06749006 0,15569421 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,06749006 0,1555382 ! melanin metabolic process GO:0006582 12 8 0,000 0,06749006 0,15538251 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,06749006 0,15522713 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,06749006 0,15507206 ! macrophage activation GO:0042116 12 8 0,000 0,06749006 0,15491729 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,06749006 0,15476284 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,06749006 0,15460869 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,06749006 0,15445485 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,06749006 0,15430132 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,06749006 0,15414809 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,06749006 0,15399517 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,06749006 0,15384255 ! ruffle organization GO:0031529 11 8 0,000 0,06749006 0,15369023 ! osteoblast development GO:0002076 13 8 0,000 0,06749006 0,15353821 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,06749006 0,15338649 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,06749006 0,15323507 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,06749006 0,15308395 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,06749006 0,15293313 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,06749006 0,15278261 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,06749006 0,15263238 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,06749006 0,15248244 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,06749006 0,1523328 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,06749006 0,15218346 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,06749006 0,15203441 ! oligodendrocyte development GO:0014003 8 8 0,000 0,06749006 0,15188564 ! segment specification GO:0007379 10 8 0,000 0,06749006 0,15173717 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,06749006 0,15158899 ! cellular extravasation GO:0045123 11 8 0,000 0,06749006 0,1514411 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,06749006 0,1512935 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,06749006 0,15114618 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,06749006 0,15099915 ! snRNA metabolic process GO:0016073 10 8 0,000 0,06749006 0,15085241 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,06749006 0,15070595 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,06749006 0,15055978 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,06749006 0,15041388 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,06749006 0,15026828 ! nucleosome disassembly GO:0006337 12 8 0,000 0,06749006 0,15012295 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,06749006 0,1499779 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,06749006 0,14983314 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,06749006 0,14968865 ! icosanoid secretion GO:0032309 12 8 0,000 0,06749006 0,14954444 GO:0050482|arachidonic acid secretion, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,06749006 0,14940051 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,06749006 0,14925685 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,06749006 0,14911348 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,06749006 0,14897037 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,06749006 0,14882754 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,06749006 0,14868499 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,06749006 0,14854271 ! sterol catabolic process GO:0016127 9 8 0,000 0,06749006 0,1484007 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,06749006 0,14825896 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,06749006 0,14811749 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,06749006 0,14797629 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,06749006 0,14783536 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,06749006 0,1476947 ! prophase GO:0051324 11 8 0,000 0,06749006 0,1475543 ! S phase GO:0051320 8 8 0,000 0,06749006 0,14741418 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,06749006 0,14727432 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,06749006 0,14713472 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,06749006 0,14699539 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,06749006 0,14685632 ! hormone catabolic process GO:0042447 13 8 0,000 0,06749006 0,14671751 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,06749006 0,14657897 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,06749006 0,14644069 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,06749006 0,14630267 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,06749006 0,1461649 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,06749006 0,1460274 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,06749006 0,14589016 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,06749006 0,14575317 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,06749006 0,14561644 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,06749006 0,14547997 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,06749006 0,14534375 ! lamellipodium assembly GO:0030032 9 8 0,000 0,06749006 0,14520779 ! regulation of embryonic development GO:0045995 16 8 0,000 0,06749006 0,14507208 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,06749006 0,14493663 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,06749006 0,14480143 ! regulation of angiogenesis GO:0045765 94 49 1,000 0,06773733 0,14519652 ! morphogenesis of a branching structure GO:0001763 86 49 1,000 0,06773733 0,14506133 ! cartilage development GO:0051216 70 49 1,000 0,06773733 0,14492639 ! ear development GO:0043583 72 50 1,000 0,0701693 0,14999015 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 0,0701693 0,14985088 ! lipid modification GO:0030258 73 50 1,000 0,0701693 0,14971188 ! positive regulation of growth GO:0045927 67 50 1,000 0,0701693 0,14957312 ! regulation of multicellular organism growth GO:0040014 65 50 1,000 0,0701693 0,14943463 ! positive regulation of secretion GO:0051047 71 51 1,000 0,07262956 0,15453097 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,07262956 0,15438815 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,07262956 0,15424559 ! transition metal ion transport GO:0000041 74 52 1,000 0,07511742 0,15938197 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,07511742 0,15923508 ! aging GO:0007568 79 52 1,000 0,07511742 0,15908845 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,07560162 0,15996663 ! regulation of developmental growth GO:0048638 13 9 0,000 0,07560162 0,15981961 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,07560162 0,15967285 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,07560162 0,15952636 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,07560162 0,15938014 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,07560162 0,15923419 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,07560162 0,1590885 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,07560162 0,15894308 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,07560162 0,15879793 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,07560162 0,15865304 ! GTP metabolic process GO:0046039 9 9 0,000 0,07560162 0,15850841 ! elastic fiber assembly GO:0048251 13 9 0,000 0,07560162 0,15836405 ! social behavior GO:0035176 14 9 0,000 0,07560162 0,15821996 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,07560162 0,15807612 ! artery development GO:0060840 19 9 0,000 0,07560162 0,15793254 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,07560162 0,15778923 ! regulation of glycolysis GO:0006110 15 9 0,000 0,07560162 0,15764617 ! response to pain GO:0048265 16 9 0,000 0,07560162 0,15750338 ! protein complex disassembly GO:0043241 17 9 0,000 0,07560162 0,15736084 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,07560162 0,15721856 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,07560162 0,15707654 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,07560162 0,15693478 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,07560162 0,15679326 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,07560162 0,15665201 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,07560162 0,15651101 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,07560162 0,15637026 ! protein targeting to ER GO:0045047 19 9 0,000 0,07560162 0,15622977 ! T cell selection GO:0045058 18 9 0,000 0,07560162 0,15608953 ! endoderm development GO:0007492 12 9 0,000 0,07560162 0,15594953 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,07560162 0,15580979 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,07560162 0,15567031 ! arginine catabolic process GO:0006527 10 9 0,000 0,07560162 0,15553107 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,07560162 0,15539207 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,07560162 0,15525333 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,07560162 0,15511484 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,07560162 0,15497659 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,07560162 0,15483858 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,07560162 0,15470083 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,07560162 0,15456332 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,07560162 0,15442605 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,07560162 0,15428902 ! mannose metabolic process GO:0006013 9 9 0,000 0,07560162 0,15415224 ! receptor clustering GO:0043113 15 9 0,000 0,07560162 0,1540157 ! epithelial cell development GO:0002064 10 9 0,000 0,07560162 0,15387941 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,07560162 0,15374335 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,07560162 0,15360754 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,07560162 0,15347196 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,07560162 0,15333662 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,07560162 0,15320153 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,07560162 0,15306666 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,07560162 0,15293204 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,07560162 0,15279765 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,07560162 0,1526635 ! blastoderm segmentation GO:0007350 11 9 0,000 0,07560162 0,15252959 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,07560162 0,15239591 ! DNA ligation GO:0006266 14 9 0,000 0,07560162 0,15226246 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,07560162 0,15212925 ! response to amine stimulus GO:0014075 13 9 0,000 0,07560162 0,15199627 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,07560162 0,15186352 ! erythrocyte development GO:0048821 11 9 0,000 0,07560162 0,151731 ! renal water homeostasis GO:0003091 14 9 0,000 0,07560162 0,15159872 ! postreplication repair GO:0006301 11 9 0,000 0,07560162 0,15146666 ! mRNA cleavage GO:0006379 13 9 0,000 0,07560162 0,15133484 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,07560162 0,15120324 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,07560162 0,15107188 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,07560162 0,15094074 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,07560162 0,15080983 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,07560162 0,15067914 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,07560162 0,15054868 ! acid secretion GO:0046717 14 9 0,000 0,07560162 0,15041845 ! musculoskeletal movement GO:0050881 11 9 0,000 0,07560162 0,15028845 GO:0050879|multicellular organismal movement, ! methionine biosynthetic process GO:0009086 10 9 0,000 0,07560162 0,15015866 ! purine base metabolic process GO:0006144 18 9 0,000 0,07560162 0,1500291 ! oocyte differentiation GO:0009994 12 9 0,000 0,07560162 0,14989977 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,07560162 0,14977066 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,07560162 0,14964176 ! spleen development GO:0048536 15 9 0,000 0,07560162 0,1495131 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,07560162 0,14938465 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,07560162 0,14925642 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,07560162 0,14912841 ! detection of calcium ion GO:0005513 13 9 0,000 0,07560162 0,14900063 ! blastocyst formation GO:0001825 12 9 0,000 0,07560162 0,14887306 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,07560162 0,14874571 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,07560162 0,14861857 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,07560162 0,14849166 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,07560162 0,14836496 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,07560162 0,14823847 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,07560162 0,14811221 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,07560162 0,14798615 ! prepulse inhibition GO:0060134 14 9 0,000 0,07560162 0,14786032 ! embryonic placenta development GO:0001892 12 9 0,000 0,07560162 0,14773469 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,07560162 0,14760928 ! insulin secretion GO:0030073 17 9 0,000 0,07560162 0,14748408 ! sequestering of metal ion GO:0051238 11 9 0,000 0,07560162 0,14735909 ! response to nicotine GO:0035094 16 9 0,000 0,07560162 0,14723432 ! establishment of cell polarity GO:0030010 12 9 0,000 0,07560162 0,14710976 ! nucleus localization GO:0051647 15 9 0,000 0,07560162 0,1469854 ! regulation of synapse organization GO:0050807 12 9 0,000 0,07560162 0,14686126 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,07763223 0,15067859 ! kidney development GO:0001822 90 53 1,000 0,07763223 0,15055154 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,08017334 0,15534852 ! detection of external stimulus GO:0009581 66 54 1,000 0,08017334 0,15521775 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,08017334 0,15508721 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,08017334 0,15495688 ! mesoderm development GO:0007498 76 55 1,000 0,08274012 0,15978361 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,08364309 0,16139187 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,08364309 0,16125658 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,08364309 0,16112153 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,08364309 0,1609867 ! thyroid gland development GO:0030878 19 10 0,000 0,08364309 0,16085209 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,08364309 0,16071772 ! synapsis GO:0007129 13 10 0,000 0,08364309 0,16058356 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,08364309 0,16044963 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,08364309 0,16031592 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,08364309 0,16018244 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,08364309 0,16004917 ! sulfate transport GO:0008272 12 10 0,000 0,08364309 0,15991613 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,08364309 0,15978331 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,08364309 0,15965071 ! androgen metabolic process GO:0008209 13 10 0,000 0,08364309 0,15951833 ! phospholipid efflux GO:0033700 16 10 0,000 0,08364309 0,15938617 ! hippocampus development GO:0021766 19 10 0,000 0,08364309 0,15925423 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,08364309 0,1591225 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,08364309 0,158991 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,08364309 0,15885971 ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,08364309 0,15872863 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,08364309 0,15859778 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,08364309 0,15846714 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,08364309 0,15833671 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,08364309 0,1582065 ! melanocyte differentiation GO:0030318 15 10 0,000 0,08364309 0,1580765 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,08364309 0,15794672 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,08364309 0,15781715 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,08364309 0,15768779 ! response to X-ray GO:0010165 16 10 0,000 0,08364309 0,15755864 ! B cell proliferation GO:0042100 14 10 0,000 0,08364309 0,15742971 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,08364309 0,15730099 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,08364309 0,15717247 ! lipid digestion GO:0044241 15 10 0,000 0,08364309 0,15704417 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,08364309 0,15691607 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,08364309 0,15678819 ! UV protection GO:0009650 14 10 0,000 0,08364309 0,15666051 ! entry into host cell GO:0030260 20 10 0,000 0,08364309 0,15653304 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,08364309 0,15640578 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,08364309 0,15627872 ! negative regulation of ossification GO:0030279 19 10 0,000 0,08364309 0,15615187 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,08364309 0,15602523 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,08364309 0,15589879 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,08364309 0,15577255 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,08364309 0,15564653 ! regulation of organ growth GO:0046620 11 10 0,000 0,08364309 0,1555207 ! response to dsRNA GO:0043331 18 10 0,000 0,08364309 0,15539508 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,08364309 0,15526966 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,08364309 0,15514444 ! embryonic axis specification GO:0000578 12 10 0,000 0,08364309 0,15501942 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,08364309 0,15489461 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,08364309 0,15477 ! fucose catabolic process GO:0019317 16 10 0,000 0,08364309 0,15464558 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,08364309 0,15452137 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,08364309 0,15439736 ! protein sumoylation GO:0016925 12 10 0,000 0,08364309 0,15427354 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,08364309 0,15414992 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,08364309 0,15402651 ! zymogen activation GO:0031638 14 10 0,000 0,08364309 0,15390328 ! salivary gland development GO:0007431 22 10 0,000 0,08364309 0,15378026 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,08364309 0,15365743 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,08364309 0,1535348 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,08364309 0,15341236 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,08364309 0,15329012 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,08364309 0,15316808 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,08364309 0,15304623 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,08364309 0,15292457 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,08364309 0,1528031 ! detection of bacterium GO:0016045 10 10 0,000 0,08364309 0,15268183 ! activation of innate immune response GO:0002218 10 10 0,000 0,08364309 0,15256075 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,08364309 0,15243986 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,08364309 0,15231916 ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,08364309 0,15219866 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,08364309 0,15207834 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,08364309 0,15195822 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,08364309 0,15183828 ! multicellular organism reproduction GO:0032504 83 57 1,000 0,08794814 0,15952739 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 1,000 0,08794814 0,15940168 ! gonad development GO:0008406 79 57 1,000 0,08794814 0,15927617 ! regulation of cytokine biosynthetic process GO:0042035 76 58 1,000 0,09058815 0,16392821 ! rRNA transcription GO:0009303 17 11 0,000 0,09161506 0,16565616 ! respiratory burst GO:0045730 14 11 0,000 0,09161506 0,16552603 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,09161506 0,1653961 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,09161506 0,16526638 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,09161506 0,16513686 ! virus-host interaction GO:0019048 17 11 0,000 0,09161506 0,16500754 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,09161506 0,16487843 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,09161506 0,16474952 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,09161506 0,16462081 ! RNA polyadenylation GO:0043631 19 11 0,000 0,09161506 0,1644923 ! mating GO:0007618 14 11 0,000 0,09161506 0,16436399 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,09161506 0,16423588 ! T cell proliferation GO:0042098 20 11 0,000 0,09161506 0,16410797 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,09161506 0,16398026 ! bone resorption GO:0045453 16 11 0,000 0,09161506 0,16385275 ! regulated secretory pathway GO:0045055 14 11 0,000 0,09161506 0,16372543 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,09161506 0,16359832 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,09161506 0,1634714 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,09161506 0,16334468 ! syncytium formation GO:0006949 15 11 0,000 0,09161506 0,16321815 ! plasma membrane organization GO:0007009 18 11 0,000 0,09161506 0,16309182 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,09161506 0,16296569 ! mitotic spindle organization GO:0007052 15 11 0,000 0,09161506 0,16283975 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,09161506 0,162714 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,09161506 0,16258845 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,09161506 0,1624631 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,09161506 0,16233793 ! adult heart development GO:0007512 11 11 0,000 0,09161506 0,16221296 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,09161506 0,16208818 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,09161506 0,16196359 ! temperature homeostasis GO:0001659 16 11 0,000 0,09161506 0,1618392 ! L-glutamate transport GO:0015813 16 11 0,000 0,09161506 0,16171499 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,09161506 0,16159098 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,09161506 0,16146715 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,09161506 0,16134352 ! stem cell development GO:0048864 29 11 0,000 0,09161506 0,16122007 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,09161506 0,16109682 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,09161506 0,16097375 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,09161506 0,16085087 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,09161506 0,16072817 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,09161506 0,16060567 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,09161506 0,16048335 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,09161506 0,16036121 ! ribosome assembly GO:0042255 13 11 0,000 0,09161506 0,16023927 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,09161506 0,1601175 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,09161506 0,15999593 ! chromatin silencing GO:0006342 19 11 0,000 0,09161506 0,15987453 ! T cell homeostasis GO:0043029 20 11 0,000 0,09161506 0,15975332 ! regulation of isotype switching GO:0045191 19 11 0,000 0,09161506 0,1596323 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,09161506 0,15951146 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,09161506 0,1593908 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,09161506 0,15927032 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,09161506 0,15915003 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,09161506 0,15902991 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,09161506 0,15890998 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,09161506 0,15879023 ! male genitalia development GO:0030539 13 11 0,000 0,09161506 0,15867066 ! cholesterol efflux GO:0033344 19 11 0,000 0,09161506 0,15855127 ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,09161506 0,15843206 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,09161506 0,15831302 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,09161506 0,15819417 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,09161506 0,15807549 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,09161506 0,157957 ! defense response to fungus GO:0050832 12 11 0,000 0,09161506 0,15783868 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,09161506 0,15772054 ! lysogeny GO:0030069 18 11 0,000 0,09161506 0,15760257 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,09161506 0,15748478 ! acrosome reaction GO:0007340 13 11 0,000 0,09161506 0,15736717 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,09161506 0,15724973 ! actin filament organization GO:0007015 95 59 1,000 0,09325135 0,15993894 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,09593715 0,16442283 ! embryonic limb morphogenesis GO:0030326 86 60 1,000 0,09593715 0,1643004 GO:0035113|embryonic appendage morphogenesis, ! regulation of cellular response to stress GO:0080135 85 61 1,000 0,09864495 0,16881204 ! meiosis GO:0007126 96 61 1,000 0,09864495 0,16868653 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 1,000 0,09864495 0,1685612 ! urogenital system development GO:0001655 101 61 1,000 0,09864495 0,16843607 ! lactation GO:0007595 20 12 0,000 0,09951813 0,16980096 ! reproductive cellular process GO:0048610 14 12 0,000 0,09951813 0,16967509 ! tRNA modification GO:0006400 14 12 0,000 0,09951813 0,1695494 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,09951813 0,1694239 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,09951813 0,16929859 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,09951813 0,16917346 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,09951813 0,16904852 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,09951813 0,16892376 ! non-recombinational repair GO:0000726 19 12 0,000 0,09951813 0,16879918 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,09951813 0,16867479 ! peroxisomal transport GO:0043574 21 12 0,000 0,09951813 0,16855058 ! cartilage condensation GO:0001502 18 12 0,000 0,09951813 0,16842656 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,09951813 0,16830272 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,09951813 0,16817905 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,09951813 0,16805557 ! heart looping GO:0001947 15 12 0,000 0,09951813 0,16793228 ! palate development GO:0060021 15 12 0,000 0,09951813 0,16780916 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,09951813 0,16768622 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,09951813 0,16756346 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,09951813 0,16744089 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,09951813 0,16731849 ! arginine metabolic process GO:0006525 13 12 0,000 0,09951813 0,16719627 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,09951813 0,16707423 ! methionine metabolic process GO:0006555 13 12 0,000 0,09951813 0,16695237 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,09951813 0,16683068 ! Golgi organization GO:0007030 18 12 0,000 0,09951813 0,16670917 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,09951813 0,16658784 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,09951813 0,16646669 ! monoamine transport GO:0015844 13 12 0,000 0,09951813 0,16634571 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,09951813 0,1662249 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,09951813 0,16610428 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,09951813 0,16598382 ! L-amino acid transport GO:0015807 20 12 0,000 0,09951813 0,16586355 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,09951813 0,16574344 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,09951813 0,16562351 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,09951813 0,16550375 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,09951813 0,16538417 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,09951813 0,16526476 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,09951813 0,16514552 ! cerebellum development GO:0021549 13 12 0,000 0,09951813 0,16502645 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,09951813 0,16490756 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,09951813 0,16478884 ! histone methylation GO:0016571 15 12 0,000 0,09951813 0,16467028 ! autonomic nervous system development GO:0048483 23 12 0,000 0,09951813 0,1645519 ! gland morphogenesis GO:0022612 23 12 0,000 0,09951813 0,16443369 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,09951813 0,16431564 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,09951813 0,16419777 ! response to gamma radiation GO:0010332 20 12 0,000 0,09951813 0,16408007 ! regulation of epidermis development GO:0045682 17 12 0,000 0,09951813 0,16396253 ! intestinal absorption GO:0050892 19 12 0,000 0,09951813 0,16384516 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,09951813 0,16372796 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,09951813 0,16361093 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,09951813 0,16349407 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,09951813 0,16337737 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,09951813 0,16326084 ! microspike assembly GO:0030035 23 12 0,000 0,09951813 0,16314447 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,09951813 0,16302827 ! response to cold GO:0009409 14 12 0,000 0,09951813 0,16291224 ! meiotic cell cycle GO:0051321 97 62 1,000 0,10137417 0,16583258 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 1,000 0,10412426 0,17021023 ! regulation of lipase activity GO:0060191 109 63 1,000 0,10412426 0,17008934 ! adaptive immune response GO:0002250 94 64 1,000 0,10689463 0,17449088 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,10735289 0,17511464 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,10735289 0,17499053 ! cGMP metabolic process GO:0046068 16 13 0,000 0,10735289 0,1748666 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,10735289 0,17474284 ! water transport GO:0006833 17 13 0,000 0,10735289 0,17461926 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,10735289 0,17449586 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,10735289 0,17437263 ! lipid localization GO:0010876 24 13 0,000 0,10735289 0,17424957 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,10735289 0,17412668 ! organelle fusion GO:0048284 28 13 0,000 0,10735289 0,17400397 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,10735289 0,17388144 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,10735289 0,17375907 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,10735289 0,17363688 ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,10735289 0,17351486 ! glutamate metabolic process GO:0006536 18 13 0,000 0,10735289 0,173393 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,10735289 0,17327133 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,10735289 0,17314982 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,10735289 0,17302848 ! NAD metabolic process GO:0019674 21 13 0,000 0,10735289 0,17290731 ! exocrine system development GO:0035272 27 13 0,000 0,10735289 0,17278631 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,10735289 0,17266548 ! regulation of exocytosis GO:0017157 17 13 0,000 0,10735289 0,17254482 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,10735289 0,17242433 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,10735289 0,172304 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,10735289 0,17218385 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,10735289 0,17206386 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,10735289 0,17194404 ! genitalia development GO:0048806 15 13 0,000 0,10735289 0,17182438 ! regulation of cellular pH GO:0030641 20 13 0,000 0,10735289 0,17170489 ! cellular pigmentation GO:0033059 24 13 0,000 0,10735289 0,17158557 ! tissue regeneration GO:0042246 21 13 0,000 0,10735289 0,17146642 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,10735289 0,17134742 ! cofactor transport GO:0051181 19 13 0,000 0,10735289 0,1712286 ! NADP metabolic process GO:0006739 18 13 0,000 0,10735289 0,17110994 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,10735289 0,17099144 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,10735289 0,17087311 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,10735289 0,17075494 ! gas transport GO:0015669 18 13 0,000 0,10735289 0,17063693 ! heme biosynthetic process GO:0006783 20 13 0,000 0,10735289 0,17051909 ! regulation of axon extension GO:0030516 23 13 0,000 0,10735289 0,17040141 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,10735289 0,17028389 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,10735289 0,17016653 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,10735289 0,17004934 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,10735289 0,1699323 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,10735289 0,16981543 ! reproductive structure development GO:0048608 90 65 1,000 0,10968474 0,17338482 ! defense response to bacterium GO:0042742 73 65 1,000 0,10968474 0,17326573 ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 0,10968474 0,17314681 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,11249404 0,17745974 ! regulation of immune effector process GO:0002697 101 66 1,000 0,11249404 0,17733811 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,11511992 0,1813533 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,11511992 0,18122917 ! superoxide anion generation GO:0042554 18 14 0,000 0,11511992 0,18110521 ! neuron maturation GO:0042551 21 14 0,000 0,11511992 0,18098142 ! regulation of S phase GO:0033261 18 14 0,000 0,11511992 0,1808578 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,11511992 0,18073435 ! myotube differentiation GO:0014902 21 14 0,000 0,11511992 0,18061107 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,11511992 0,18048795 ! inositol metabolic process GO:0006020 20 14 0,000 0,11511992 0,180365 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,11511992 0,18024222 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,11511992 0,18011961 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,11511992 0,17999716 ! gene silencing by RNA GO:0031047 20 14 0,000 0,11511992 0,17987488 ! response to cAMP GO:0051591 19 14 0,000 0,11511992 0,17975277 ! startle response GO:0001964 21 14 0,000 0,11511992 0,17963082 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,11511992 0,17950903 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,11511992 0,17938741 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,11511992 0,17926596 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,11511992 0,17914467 ! glycine metabolic process GO:0006544 22 14 0,000 0,11511992 0,17902354 ! cellular response to starvation GO:0009267 21 14 0,000 0,11511992 0,17890258 ! lysosomal transport GO:0007041 20 14 0,000 0,11511992 0,17878178 ! regulation of heart rate GO:0002027 23 14 0,000 0,11511992 0,17866115 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,11511992 0,17854068 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,11511992 0,17842037 ! embryo implantation GO:0007566 27 14 0,000 0,11511992 0,17830022 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,11511992 0,17818023 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,11511992 0,17806041 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,11511992 0,17794074 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,11511992 0,17782124 ! axon cargo transport GO:0008088 27 14 0,000 0,11511992 0,17770189 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,11511992 0,17758271 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,11511992 0,17746369 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,11511992 0,17734482 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,11511992 0,17722612 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,11511992 0,17710757 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,11511992 0,17698919 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,11511992 0,17687096 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,11511992 0,17675289 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,11511992 0,17663497 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,11511992 0,17651722 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,11511992 0,17639962 ! muscle maintenance GO:0046716 19 14 0,000 0,11511992 0,17628217 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,11511992 0,17616489 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,11511992 0,17604775 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,11511992 0,17593078 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,11511992 0,17581396 ! cell killing GO:0001906 20 14 0,000 0,11511992 0,17569729 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,11511992 0,17558078 ! cilium assembly GO:0042384 20 14 0,000 0,11511992 0,17546443 ! peptide hormone secretion GO:0030072 23 14 0,000 0,11511992 0,17534823 ! regulation of neuron differentiation GO:0045664 107 67 1,000 0,115322 0,17553977 ! learning or memory GO:0007611 123 68 1,000 0,11816807 0,17975302 ! development of primary sexual characteristics GO:0045137 92 68 1,000 0,11816807 0,17963422 ! rhythmic process GO:0048511 105 68 1,000 0,11816807 0,17951557 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,12281982 0,18645913 ! positive regulation of cell size GO:0045793 20 15 0,000 0,12281982 0,18633614 ! metencephalon development GO:0022037 19 15 0,000 0,12281982 0,1862133 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,12281982 0,18609063 ! skin development GO:0043588 25 15 0,000 0,12281982 0,18596813 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,12281982 0,18584578 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,12281982 0,18572359 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,12281982 0,18560157 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,12281982 0,1854797 ! bile acid metabolic process GO:0008206 22 15 0,000 0,12281982 0,18535799 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,12281982 0,18523645 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,12281982 0,18511506 ! adult walking behavior GO:0007628 25 15 0,000 0,12281982 0,18499383 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,12281982 0,18487276 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,12281982 0,18475185 ! centrosome cycle GO:0007098 16 15 0,000 0,12281982 0,1846311 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,12281982 0,1845105 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,12281982 0,18439007 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,12281982 0,18426979 ! response to osmotic stress GO:0006970 22 15 0,000 0,12281982 0,18414966 ! vesicle coating GO:0006901 25 15 0,000 0,12281982 0,1840297 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,12281982 0,18390988 ! DNA integration GO:0015074 22 15 0,000 0,12281982 0,18379023 ! peptide secretion GO:0002790 27 15 0,000 0,12281982 0,18367073 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,12281982 0,18355139 ! regulation of vasodilation GO:0042312 24 15 0,000 0,12281982 0,1834322 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,12281982 0,18331316 ! neuron recognition GO:0008038 22 15 0,000 0,12281982 0,18319428 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,12281982 0,18307556 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,12281982 0,18295698 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,12281982 0,18283856 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,12281982 0,1827203 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,12281982 0,18260219 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,12281982 0,18248423 ! dopamine metabolic process GO:0042417 30 15 0,000 0,12281982 0,18236642 ! organic cation transport GO:0015695 19 15 0,000 0,12281982 0,18224876 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,12281982 0,18213126 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,12281982 0,18201391 ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,12281982 0,1818967 ! defense response to virus GO:0051607 27 15 0,000 0,12281982 0,18177965 ! peptide hormone processing GO:0016486 19 15 0,000 0,12281982 0,18166275 ! humoral immune response GO:0006959 86 70 1,000 0,1239125 0,18316115 ! positive regulation of phosphorylation GO:0042327 102 70 1,000 0,1239125 0,18304352 ! muscle cell differentiation GO:0042692 104 71 1,000 0,12680983 0,18720321 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 1,000 0,12972323 0,19138129 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of synaptic transmission GO:0050804 109 72 1,000 0,12972323 0,19125861 ! protein secretion GO:0009306 27 16 0,000 0,13045315 0,19221156 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,13045315 0,1920885 ! hormone secretion GO:0046879 25 16 0,000 0,13045315 0,19196561 ! bone remodeling GO:0046849 24 16 0,000 0,13045315 0,19184287 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,13045315 0,19172028 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,13045315 0,19159786 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,13045315 0,19147559 ! patterning of blood vessels GO:0001569 24 16 0,000 0,13045315 0,19135347 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,13045315 0,19123151 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,13045315 0,19110971 ! protein polyubiquitination GO:0000209 26 16 0,000 0,13045315 0,19098806 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,13045315 0,19086657 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,13045315 0,19074523 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,13045315 0,19062404 ! fructose metabolic process GO:0006000 20 16 0,000 0,13045315 0,19050301 ! regulation of protein binding GO:0043393 27 16 0,000 0,13045315 0,19038213 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,13045315 0,19026141 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,13045315 0,19014084 ! protein export from nucleus GO:0006611 24 16 0,000 0,13045315 0,19002042 ! negative regulation of immune response GO:0050777 28 16 0,000 0,13045315 0,18990015 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,13045315 0,18978004 ! DNA replication initiation GO:0006270 25 16 0,000 0,13045315 0,18966008 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,13045315 0,18954027 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,13045315 0,18942061 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,13045315 0,1893011 ! oogenesis GO:0048477 23 16 0,000 0,13045315 0,18918174 ! neural crest cell migration GO:0001755 24 16 0,000 0,13045315 0,18906253 ! G1 phase GO:0051318 27 16 0,000 0,13045315 0,18894348 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,13045315 0,18882457 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,13045315 0,18870581 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,13045315 0,1885872 ! steroid catabolic process GO:0006706 22 16 0,000 0,13045315 0,18846875 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,13045315 0,18835043 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,13045315 0,18823227 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,13045315 0,18811426 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,13045315 0,18799639 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,13045315 0,18787867 ! sperm-egg recognition GO:0035036 16 16 0,000 0,13045315 0,1877611 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,13045315 0,18764368 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,13045315 0,1875264 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,13045315 0,18740927 ! negative regulation of translation GO:0017148 22 16 0,000 0,13045315 0,18729229 ! regulation of blood pressure GO:0008217 107 73 1,000 0,13265221 0,19033068 ! tube morphogenesis GO:0035239 118 73 1,000 0,13265221 0,19021202 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,13559628 0,19431243 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,13802049 0,19766321 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,13802049 0,19754021 ! negative regulation of defense response GO:0031348 19 17 0,000 0,13802049 0,19741736 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,13802049 0,19729467 ! glycerol metabolic process GO:0006071 20 17 0,000 0,13802049 0,19717212 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,13802049 0,19704973 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,13802049 0,19692749 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,13802049 0,19680541 ! signal complex assembly GO:0007172 29 17 0,000 0,13802049 0,19668347 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,13802049 0,19656168 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,13802049 0,19644005 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,13802049 0,19631857 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,13802049 0,19619723 ! memory GO:0007613 25 17 0,000 0,13802049 0,19607605 ! keratinization GO:0031424 17 17 0,000 0,13802049 0,19595501 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,13802049 0,19583413 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,13802049 0,19571339 ! retinoid metabolic process GO:0001523 22 17 0,000 0,13802049 0,1955928 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,13802049 0,19547236 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,13802049 0,19535207 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,13802049 0,19523193 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,13802049 0,19511194 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,13802049 0,19499209 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,13802049 0,19487239 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,13802049 0,19475283 ! membrane budding GO:0006900 29 17 0,000 0,13802049 0,19463343 ! heme metabolic process GO:0042168 27 17 0,000 0,13802049 0,19451417 ! body fluid secretion GO:0007589 27 17 0,000 0,13802049 0,19439505 ! stem cell differentiation GO:0048863 36 17 0,000 0,13802049 0,19427608 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,13802049 0,19415726 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,13802049 0,19403858 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,13802049 0,19392005 ! sensory perception of pain GO:0019233 23 17 0,000 0,13802049 0,19380166 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,13802049 0,19368342 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,13802049 0,19356532 ! synaptogenesis GO:0007416 24 17 0,000 0,13802049 0,19344736 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,13802049 0,19332955 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,13802049 0,19321188 ! cell-cell junction organization GO:0045216 25 17 0,000 0,13802049 0,19309436 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,13802049 0,19297697 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,13802049 0,19285973 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,13802049 0,19274263 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,13802049 0,19262568 ! blood coagulation GO:0007596 116 75 1,000 0,13855497 0,19325435 GO:0050817|coagulation, ! tRNA metabolic process GO:0006399 95 76 1,000 0,1415278 0,19728117 ! sex differentiation GO:0007548 105 77 1,000 0,1445143 0,20132217 ! protein ubiquitination GO:0016567 125 77 1,000 0,1445143 0,2012003 ! regulation of transmission of nerve impulse GO:0051969 116 77 1,000 0,1445143 0,20107858 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,1455224 0,20235884 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,1455224 0,20223657 ! positive regulation of translation GO:0045727 28 18 0,000 0,1455224 0,20211444 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,1455224 0,20199247 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,1455224 0,20187064 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,1455224 0,20174896 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,1455224 0,20162742 ! cAMP metabolic process GO:0046058 33 18 0,000 0,1455224 0,20150603 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,1455224 0,20138479 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,1455224 0,20126369 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,1455224 0,20114274 ! axis specification GO:0009798 26 18 0,000 0,1455224 0,20102193 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,1455224 0,20090127 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,1455224 0,20078075 ! glutamine metabolic process GO:0006541 23 18 0,000 0,1455224 0,20066038 ! response to retinoic acid GO:0032526 25 18 0,000 0,1455224 0,20054015 ! pigmentation during development GO:0048066 31 18 0,000 0,1455224 0,20042007 ! central nervous system neuron development GO:0021954 30 18 0,000 0,1455224 0,20030013 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,1455224 0,20018033 ! fucose metabolic process GO:0006004 26 18 0,000 0,1455224 0,20006068 ! response to fungus GO:0009620 19 18 0,000 0,1455224 0,19994117 ! peptide cross-linking GO:0018149 31 18 0,000 0,1455224 0,1998218 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,1455224 0,19970258 ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,1455224 0,19958349 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,1455224 0,19946455 ! visual learning GO:0008542 35 18 0,000 0,1455224 0,19934575 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,1455224 0,19922709 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,1455224 0,19910858 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,1455224 0,1989902 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,1455224 0,19887196 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,1455224 0,19875387 ! vitamin transport GO:0051180 24 18 0,000 0,1455224 0,19863591 ! hormone transport GO:0009914 27 18 0,000 0,1455224 0,1985181 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,1455224 0,19840042 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,1455224 0,19828289 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,1455224 0,19816549 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,1455224 0,19804823 ! cell-cell recognition GO:0009988 20 18 0,000 0,1455224 0,19793112 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,1455224 0,19781413 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,1455224 0,19769729 ! regulation of glucose import GO:0046324 21 18 0,000 0,1455224 0,19758059 GO:0010827|regulation of glucose transport, ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,1455224 0,19746402 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,15295945 0,20743321 ! positive regulation of ossification GO:0045778 30 19 0,000 0,15295945 0,20731098 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,15295945 0,20718888 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,15295945 0,20706694 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,15295945 0,20694513 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,15295945 0,20682347 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,15295945 0,20670195 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,15295945 0,20658058 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,15295945 0,20645935 ! regeneration GO:0031099 32 19 0,000 0,15295945 0,20633826 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,15295945 0,20621731 ! sensory perception of taste GO:0050909 23 19 0,000 0,15295945 0,2060965 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,15295945 0,20597583 ! peroxisome organization GO:0007031 29 19 0,000 0,15295945 0,20585531 ! digestive system process GO:0022600 30 19 0,000 0,15295945 0,20573493 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,15295945 0,20561468 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,15295945 0,20549458 ! response to vitamin A GO:0033189 26 19 0,000 0,15295945 0,20537462 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,15295945 0,2052548 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,15295945 0,20513512 ! response to starvation GO:0042594 30 19 0,000 0,15295945 0,20501557 ! sex determination GO:0007530 29 19 0,000 0,15295945 0,20489617 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,15295945 0,20477691 ! plasma membrane fusion GO:0045026 23 19 0,000 0,15295945 0,20465778 ! cytolysis GO:0019835 20 19 0,000 0,15295945 0,20453879 ! renal system process GO:0003014 35 19 0,000 0,15295945 0,20441994 ! vasodilation GO:0042311 33 19 0,000 0,15295945 0,20430123 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,15295945 0,20418266 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,15295945 0,20406423 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,15295945 0,20394593 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,15295945 0,20382777 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,15295945 0,20370974 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,15295945 0,20359185 ! sarcomere organization GO:0045214 23 19 0,000 0,15295945 0,2034741 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,15295945 0,20335649 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,15295945 0,20323901 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,15295945 0,20312167 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,15295945 0,20300446 ! protein stabilization GO:0050821 26 19 0,000 0,15295945 0,20288738 ! chromatin assembly GO:0031497 102 80 1,000 0,15355134 0,20355509 GO:0006334|nucleosome assembly, ! hemostasis GO:0007599 125 81 1,000 0,15658804 0,20746111 ! regulation of neurological system process GO:0031644 122 81 1,000 0,15658804 0,20734167 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,15658804 0,20722238 GO:0002696|positive regulation of leukocyte activation, ! detection of stimulus GO:0051606 108 82 1,000 0,1596362 0,2111347 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,16033219 0,21193335 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,16033219 0,21181162 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,16033219 0,21169003 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,16033219 0,21156858 ! response to vitamin GO:0033273 29 20 0,000 0,16033219 0,21144726 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,16033219 0,21132609 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,16033219 0,21120506 ! response to ethanol GO:0045471 37 20 0,000 0,16033219 0,21108416 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,16033219 0,2109634 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,16033219 0,21084278 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,16033219 0,2107223 ! chromosome condensation GO:0030261 31 20 0,000 0,16033219 0,21060196 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,16033219 0,21048175 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,16033219 0,21036168 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,16033219 0,21024175 ! DNA modification GO:0006304 28 20 0,000 0,16033219 0,21012195 ! collagen fibril organization GO:0030199 45 20 0,000 0,16033219 0,21000229 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,16033219 0,20988277 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,16033219 0,20976338 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,16033219 0,20964413 ! collagen catabolic process GO:0030574 25 20 0,000 0,16033219 0,20952502 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,16033219 0,20940604 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,16033219 0,20928719 ! alditol metabolic process GO:0019400 24 20 0,000 0,16033219 0,20916848 ! actin filament-based movement GO:0030048 34 20 0,000 0,16033219 0,2090499 ! regulation of defense response GO:0031347 117 84 1,000 0,16576518 0,21601128 ! protein-DNA complex assembly GO:0065004 107 84 1,000 0,16576518 0,21588897 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,16764117 0,21820866 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,16764117 0,21808523 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,16764117 0,21796195 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,16764117 0,21783881 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,16764117 0,21771581 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,16764117 0,21759294 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,16764117 0,21747022 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,16764117 0,21734763 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,16764117 0,21722518 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,16764117 0,21710287 ! vesicle docking GO:0048278 27 21 0,000 0,16764117 0,2169807 ! phototransduction GO:0007602 25 21 0,000 0,16764117 0,21685866 ! visual behavior GO:0007632 39 21 0,000 0,16764117 0,21673676 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,16764117 0,216615 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,16764117 0,21649337 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,16764117 0,21637188 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,16764117 0,21625053 ! cell aging GO:0007569 32 21 0,000 0,16764117 0,21612931 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,16764117 0,21600823 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,16764117 0,21588729 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,16764117 0,21576648 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,16764117 0,2156458 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,16764117 0,21552526 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,16764117 0,21540486 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,16764117 0,21528459 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,16764117 0,21516445 ! fatty acid transport GO:0015908 30 21 0,000 0,16764117 0,21504445 ! immunoglobulin production GO:0002377 33 21 0,000 0,16764117 0,21492458 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,16764117 0,21480484 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,16764117 0,21468524 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,16764117 0,21456577 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,16764117 0,21444644 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,16764117 0,21432723 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,16764117 0,21420816 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,16764117 0,21408923 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,16764117 0,21397042 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,16764117 0,21385174 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,16764117 0,2137332 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,16764117 0,21361479 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,16764117 0,21349651 GO:0006099|tricarboxylic acid cycle, ! regulation of DNA metabolic process GO:0051052 135 85 1,000 0,16884518 0,21491085 ! rRNA metabolic process GO:0016072 107 85 1,000 0,16884518 0,21479199 GO:0006364|rRNA processing, ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,16884518 0,21467325 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,17488695 0,22223204 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,17488695 0,22210932 ! viral genome replication GO:0019079 29 22 0,000 0,17488695 0,22198675 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,17488695 0,22186431 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,17488695 0,221742 ! leukocyte adhesion GO:0007159 38 22 0,000 0,17488695 0,22161983 ! molting cycle process GO:0022404 40 22 0,000 0,17488695 0,22149779 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,17488695 0,22137589 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,17488695 0,22125412 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,17488695 0,22113248 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,17488695 0,22101098 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,17488695 0,22088961 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,17488695 0,22076838 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,17488695 0,22064728 ! lysosome organization GO:0007040 37 22 0,000 0,17488695 0,22052631 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,17488695 0,22040547 GO:0051693|actin filament capping, ! coenzyme catabolic process GO:0009109 33 22 0,000 0,17488695 0,22028477 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,17488695 0,2201642 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,17488695 0,22004376 ! membrane depolarization GO:0051899 35 22 0,000 0,17488695 0,21992345 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,17488695 0,21980327 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,17488695 0,21968323 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,17488695 0,21956331 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,17488695 0,21944353 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,17488695 0,21932387 ! blastocyst development GO:0001824 37 22 0,000 0,17488695 0,21920435 ! neural tube closure GO:0001843 33 22 0,000 0,17488695 0,21908496 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,17488695 0,2189657 ! protein tetramerization GO:0051262 39 22 0,000 0,17488695 0,21884656 ! nucleosome organization GO:0034728 114 87 1,000 0,17503416 0,21891167 ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,17503416 0,2187927 ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,17814235 0,22255698 ! regulation of neurogenesis GO:0050767 153 89 1,000 0,18125915 0,22632793 ! reproductive developmental process GO:0003006 127 89 1,000 0,18125915 0,22620512 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,18207007 0,2270939 ! embryonic pattern specification GO:0009880 31 23 0,000 0,18207007 0,22697081 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,18207007 0,22684786 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,18207007 0,22672504 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,18207007 0,22660235 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,18207007 0,2264798 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,18207007 0,22635738 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,18207007 0,22623509 ! osteoblast differentiation GO:0001649 40 23 0,000 0,18207007 0,22611293 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,18207007 0,22599091 ! interaction with host GO:0051701 37 23 0,000 0,18207007 0,22586901 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,18207007 0,22574725 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,18207007 0,22562562 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,18207007 0,22550412 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,18207007 0,22538275 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,18207007 0,22526151 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,18207007 0,2251404 ! cell fate determination GO:0001709 45 23 0,000 0,18207007 0,22501943 ! pentose metabolic process GO:0019321 31 23 0,000 0,18207007 0,22489858 ! spermatid development GO:0007286 33 23 0,000 0,18207007 0,22477786 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,18207007 0,22465727 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,18207007 0,22453681 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,18207007 0,22441648 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,18207007 0,22429628 ! telomere organization GO:0032200 32 23 0,000 0,18207007 0,2241762 GO:0000723|telomere maintenance, ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,18207007 0,22405626 ! regulation of amine transport GO:0051952 38 23 0,000 0,18207007 0,22393644 ! liver development GO:0001889 40 23 0,000 0,18207007 0,22381676 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,18438419 0,2265404 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,18919105 0,23232217 ! initiation of viral infection GO:0019059 42 24 0,000 0,18919105 0,2321982 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,18919105 0,23207436 ! superoxide metabolic process GO:0006801 32 24 0,000 0,18919105 0,23195065 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,18919105 0,23182708 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,18919105 0,23170363 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,18919105 0,23158032 ! sperm motility GO:0030317 27 24 0,000 0,18919105 0,23145714 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,18919105 0,23133409 ! vacuole organization GO:0007033 39 24 0,000 0,18919105 0,23121117 ! receptor metabolic process GO:0043112 37 24 0,000 0,18919105 0,23108838 ! neural crest cell development GO:0014032 39 24 0,000 0,18919105 0,23096572 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,18919105 0,2308432 ! primary neural tube formation GO:0014020 35 24 0,000 0,18919105 0,2307208 ! negative regulation of cell development GO:0010721 56 24 0,000 0,18919105 0,23059853 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,18919105 0,23047639 ! base-excision repair GO:0006284 31 24 0,000 0,18919105 0,23035438 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,18919105 0,2302325 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glutathione metabolic process GO:0006749 29 24 0,000 0,18919105 0,23011075 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,18919105 0,22998913 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,18919105 0,22986763 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,18919105 0,22974626 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,19065746 0,23140483 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,19380497 0,23510096 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,19380497 0,23497703 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,19625045 0,23781667 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,19625045 0,23769144 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,19625045 0,23756634 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,19625045 0,23744137 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,19625045 0,23731653 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,19625045 0,23719182 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,19625045 0,23706725 ! peptide transport GO:0015833 43 25 0,000 0,19625045 0,2369428 ! male gonad development GO:0008584 33 25 0,000 0,19625045 0,23681849 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,19625045 0,2366943 ! phospholipid transport GO:0015914 35 25 0,000 0,19625045 0,23657025 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,19625045 0,23644633 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,19625045 0,23632253 ! detection of light stimulus GO:0009583 30 25 0,000 0,19625045 0,23619887 ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,19625045 0,23607533 ! leukocyte proliferation GO:0070661 39 25 0,000 0,19625045 0,23595193 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,20324879 0,24423835 ! translational initiation GO:0006413 43 26 0,000 0,20324879 0,24411081 ! regulation of pH GO:0006885 36 26 0,000 0,20324879 0,24398341 ! circadian rhythm GO:0007623 42 26 0,000 0,20324879 0,24385613 ! post-embryonic development GO:0009791 42 26 0,000 0,20324879 0,24372899 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,20324879 0,24360199 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,20324879 0,24347511 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,20324879 0,24334837 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,20324879 0,24322175 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,20324879 0,24309527 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,20324879 0,24296892 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,20324879 0,24284271 ! regulation of coagulation GO:0050818 39 26 0,000 0,20324879 0,24271662 ! regulation of response to external stimulus GO:0032101 139 96 1,000 0,20328668 0,24263589 ! in utero embryonic development GO:0001701 147 96 1,000 0,20328668 0,24251004 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,20328668 0,24238432 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,21018658 0,25048142 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,21018658 0,25035171 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,21018658 0,25022212 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,21018658 0,25009268 ! membrane docking GO:0022406 39 27 0,000 0,21018658 0,24996336 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,21018658 0,24983418 ! catechol metabolic process GO:0009712 43 27 0,000 0,21018658 0,24970514 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,21018658 0,24957622 ! acute-phase response GO:0006953 42 27 0,000 0,21018658 0,24944744 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,21018658 0,24931879 ! myofibril assembly GO:0030239 36 27 0,000 0,21018658 0,24919028 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,21018658 0,2490619 ! response to ionizing radiation GO:0010212 47 27 0,000 0,21018658 0,24893365 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,21018658 0,24880553 ! natural killer cell activation GO:0030101 35 27 0,000 0,21018658 0,24867754 ! lipid oxidation GO:0034440 38 27 0,000 0,21018658 0,24854969 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,21018658 0,24842196 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,21018658 0,24829437 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,21018658 0,24816691 ! gene silencing GO:0016458 41 27 0,000 0,21018658 0,24803958 ! extracellular structure organization GO:0043062 156 99 1,000 0,21281994 0,25101839 ! regulation of body fluid levels GO:0050878 154 100 1,000 0,2160076 0,25464761 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,2160076 0,25451715 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,21706436 0,25563135 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,21706436 0,25550053 ! phenol metabolic process GO:0018958 44 28 0,000 0,21706436 0,25536984 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,21706436 0,25523928 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,21706436 0,25510886 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,21706436 0,25497857 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,21706436 0,25484841 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,21706436 0,25471839 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,21706436 0,25458849 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,21706436 0,25445873 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,21706436 0,25432911 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,21706436 0,25419961 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,21706436 0,25407025 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,21706436 0,25394101 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,21706436 0,25381191 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,21706436 0,25368294 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,21706436 0,25355411 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,21706436 0,2534254 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,21706436 0,25329682 ! BMP signaling pathway GO:0030509 40 28 0,000 0,21706436 0,25316837 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,21706436 0,25304006 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,21706436 0,25291187 ! neural tube formation GO:0001841 41 28 0,000 0,21706436 0,25278382 ! placenta development GO:0001890 37 28 0,000 0,21706436 0,25265589 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,22388264 0,26046033 ! regulation of innate immune response GO:0045088 38 29 0,000 0,22388264 0,26032865 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,22388264 0,26019711 ! mismatch repair GO:0006298 34 29 0,000 0,22388264 0,26006569 ! muscle cell development GO:0055001 38 29 0,000 0,22388264 0,25993441 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,22388264 0,25980327 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,22388264 0,25967225 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,23064193 0,26737723 ! collagen metabolic process GO:0032963 40 30 0,000 0,23064193 0,26724254 ! organic anion transport GO:0015711 51 30 0,000 0,23064193 0,26710797 ! cholesterol transport GO:0030301 46 30 0,000 0,23064193 0,26697354 GO:0015918|sterol transport, ! pigment biosynthetic process GO:0046148 50 30 0,000 0,23064193 0,26683925 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,23064193 0,26670509 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,23064193 0,26657107 ! ceramide metabolic process GO:0006672 43 30 0,000 0,23064193 0,26643718 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,23064193 0,26630343 ! adult locomotory behavior GO:0008344 47 30 0,000 0,23064193 0,26616981 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,23064193 0,26603633 ! response to heat GO:0009408 41 30 0,000 0,23064193 0,26590297 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,23064193 0,26576976 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,23734273 0,27335417 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,23734273 0,27321736 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,23734273 0,27308068 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,23734273 0,27294414 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,23734273 0,27280774 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,23734273 0,27267147 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,23734273 0,27253534 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,23734273 0,27239934 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,23734273 0,27226348 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,23734273 0,27212776 ! RNA modification GO:0009451 40 31 0,000 0,23734273 0,27199217 ! regulation of muscle development GO:0048634 48 32 0,000 0,24398555 0,27946553 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,24398555 0,27932642 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,24398555 0,27918745 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,24398555 0,27904862 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,24398555 0,27890993 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,24398555 0,27877137 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,24398555 0,27863296 ! cytokine production GO:0001816 44 32 0,000 0,24398555 0,27849468 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,24398555 0,27835654 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,2505709 0,28572784 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,2505709 0,28558625 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,2505709 0,2854448 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,2505709 0,28530349 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,2505709 0,28516233 ! actomyosin structure organization GO:0031032 43 33 0,000 0,2505709 0,2850213 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,2505709 0,2848804 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,2505709 0,28473965 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,2505709 0,28459904 ! positive regulation of cell development GO:0010720 54 33 0,000 0,2505709 0,28445857 ! lipid homeostasis GO:0055088 55 33 0,000 0,2505709 0,28431823 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,2505709 0,28417804 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,2505709 0,28403798 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,2505709 0,28389806 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,2505709 0,28375828 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,2505709 0,28361863 ! mRNA catabolic process GO:0006402 48 34 0,000 0,25709925 0,29086486 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,25709925 0,29072186 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,25709925 0,290579 ! feeding behavior GO:0007631 45 34 0,000 0,25709925 0,29043628 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,25709925 0,2902937 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,25709925 0,29015126 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,25709925 0,29000896 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,25709925 0,2898668 ! neuron migration GO:0001764 46 34 0,000 0,25709925 0,28972478 ! female gamete generation GO:0007292 43 34 0,000 0,25709925 0,28958289 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,25709925 0,28944115 ! polyol metabolic process GO:0019751 44 34 0,000 0,25709925 0,28929955 ! aerobic respiration GO:0009060 47 34 0,000 0,25709925 0,28915808 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,2635711 0,29629205 ! Notch signaling pathway GO:0007219 56 35 0,000 0,2635711 0,29614731 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,2635711 0,2960027 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,2635711 0,29585824 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,2635711 0,29571392 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,2635711 0,29556974 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,2635711 0,2954257 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,2635711 0,2952818 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,2635711 0,29513804 ! pigment metabolic process GO:0042440 61 35 0,000 0,2635711 0,29499442 ! protein homooligomerization GO:0051260 52 35 0,000 0,2635711 0,29485094 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,26998694 0,30188137 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,26998694 0,30173468 ! organic ether metabolic process GO:0018904 46 36 0,000 0,26998694 0,30158814 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,26998694 0,30144173 ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,26998694 0,30129547 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,26998694 0,30114936 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,27634725 0,30809437 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,27634725 0,3079451 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,27634725 0,30779597 ! ion transmembrane transport GO:0034220 56 37 0,000 0,27634725 0,30764699 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,27634725 0,30749815 ! regulation of protein secretion GO:0050708 51 37 0,000 0,27634725 0,30734946 ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,27634725 0,30720091 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,28265251 0,31405835 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,28265251 0,3139067 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,28265251 0,3137552 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,28265251 0,31360385 ! mesenchymal cell development GO:0014031 64 38 0,000 0,28265251 0,31345264 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of location in cell GO:0051651 69 38 0,000 0,28265251 0,31330158 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,28890319 0,32007579 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,28890319 0,31992168 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,28890319 0,31976773 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,28890319 0,31961392 ! male sex differentiation GO:0046661 53 39 0,000 0,28890319 0,31946026 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,28890319 0,31930675 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,28890319 0,31915338 ! JNK cascade GO:0007254 54 39 0,000 0,28890319 0,31900016 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,29509976 0,32568591 ! response to calcium ion GO:0051592 58 40 0,000 0,29509976 0,32552971 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,29509976 0,32537365 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,29509976 0,32521775 ! peptide metabolic process GO:0006518 56 40 0,000 0,29509976 0,32506199 ! inner ear development GO:0048839 57 40 0,000 0,29509976 0,32490639 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,29509976 0,32475093 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,29509976 0,32459562 ! double-strand break repair GO:0006302 67 40 0,000 0,29509976 0,32444046 ! B cell differentiation GO:0030183 62 40 0,000 0,29509976 0,32428545 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,29509976 0,32413058 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,29509976 0,32397587 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,30124268 0,3305621 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,30124268 0,33040446 ! endosome transport GO:0016197 71 41 0,000 0,30124268 0,33024698 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,30124268 0,33008964 ! biopolymer methylation GO:0043414 62 41 0,000 0,30124268 0,32993246 ! mitochondrial transport GO:0006839 60 42 0,000 0,30733242 0,33644196 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,30733242 0,3362819 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,30733242 0,336122 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,30733242 0,33596224 ! excretion GO:0007588 63 42 0,000 0,30733242 0,33580264 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,30733242 0,33564319 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,30733242 0,33548389 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,30733242 0,33532474 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,31336943 0,34174949 ! leukocyte migration GO:0050900 60 43 0,000 0,31336943 0,34158753 ! neuromuscular process GO:0050905 79 43 0,000 0,31336943 0,34142571 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,31336943 0,34126405 ! tRNA processing GO:0008033 49 43 0,000 0,31336943 0,34110255 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,31336943 0,34094119 ! vesicle organization GO:0016050 79 43 0,000 0,31336943 0,34077999 ! methylation GO:0032259 64 43 0,000 0,31336943 0,34061894 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,31935416 0,34696012 ! glycolysis GO:0006096 53 44 0,000 0,31935416 0,34679631 ! regulation of ion transport GO:0043269 57 44 0,000 0,31935416 0,34663265 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,31935416 0,34646914 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,31935416 0,34630579 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,31935416 0,34614259 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,31935416 0,34597955 ! RNA catabolic process GO:0006401 64 45 0,000 0,32528708 0,35224119 ! positive regulation of defense response GO:0031349 59 45 0,000 0,32528708 0,35207543 ! regulation of translational initiation GO:0006446 64 45 0,000 0,32528708 0,35190982 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,32528708 0,35174437 ! cell recognition GO:0008037 58 45 0,000 0,32528708 0,35157908 ! cell maturation GO:0048469 60 45 0,000 0,32528708 0,35141394 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,33116862 0,35759991 ! cell redox homeostasis GO:0045454 63 46 0,000 0,33116862 0,35743211 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,33116862 0,35726446 ! regulation of ossification GO:0030278 71 46 0,000 0,33116862 0,35709696 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,33116862 0,35692962 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,33699922 0,36304365 ! viral infectious cycle GO:0019058 71 47 0,000 0,33699922 0,36287369 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,33699922 0,36270389 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,33699922 0,36253424 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,33699922 0,36236475 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,33699922 0,36219542 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,33699922 0,36202625 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,33699922 0,36185724 ! chloride transport GO:0006821 67 48 0,000 0,34277932 0,36789195 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,34277932 0,36772036 ! response to temperature stimulus GO:0009266 62 48 0,000 0,34277932 0,36754892 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,34277932 0,36737765 ! heart morphogenesis GO:0003007 65 48 0,000 0,34277932 0,36720654 ! regulation of DNA replication GO:0006275 75 48 0,000 0,34277932 0,36703559 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,34277932 0,36686479 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,34277932 0,36669416 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,34277932 0,36652368 ! regulation of endocytosis GO:0030100 63 48 0,000 0,34277932 0,36635337 ! nuclear export GO:0051168 69 48 0,000 0,34277932 0,36618321 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,34277932 0,3660132 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,34850936 0,37195895 ! sensory perception of smell GO:0007608 61 49 0,000 0,34850936 0,37178643 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,34850936 0,37161406 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,34850936 0,37144186 ! RNA elongation GO:0006354 62 49 0,000 0,34850936 0,37126982 ! germ cell development GO:0007281 68 49 0,000 0,34850936 0,37109793 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,34850936 0,37092621 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,34850936 0,37075464 ! maintenance of location GO:0051235 84 49 0,000 0,34850936 0,37058324 ! regulation of actin filament length GO:0030832 72 50 0,000 0,35418977 0,37644939 ! membrane fusion GO:0006944 80 50 0,000 0,35418977 0,37627551 ! proton transport GO:0015992 75 50 0,000 0,35418977 0,37610179 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,35418977 0,37592823 ! hydrogen transport GO:0006818 77 51 0,000 0,35982098 0,3817289 ! adult behavior GO:0030534 80 51 0,000 0,35982098 0,3815529 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,35982098 0,38137707 ! regulation of cellular component size GO:0032535 74 52 0,000 0,3654034 0,38711553 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,3654034 0,3869373 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,3654034 0,38675924 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,37093746 0,39243614 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,37093746 0,39225571 ! single fertilization GO:0007338 59 53 0,000 0,37093746 0,39207544 ! amino acid transport GO:0006865 84 54 0,000 0,37642358 0,39769142 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,37642358 0,39750883 ! glucose catabolic process GO:0006007 66 54 0,000 0,37642358 0,3973264 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,37642358 0,39714414 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,37642358 0,39696205 ! exocytosis GO:0006887 74 55 0,000 0,38186216 0,40251282 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,38186216 0,40232843 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,38186216 0,40214422 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,38725362 0,40763539 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,38725362 0,40744891 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,38725362 0,40726261 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,39259836 0,4126948 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,39259836 0,41250627 ! secondary metabolic process GO:0019748 84 57 0,000 0,39259836 0,41231791 ! developmental maturation GO:0021700 75 57 0,000 0,39259836 0,41212972 ! viral reproductive process GO:0022415 87 58 0,000 0,39789678 0,41750119 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,39789678 0,41731081 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,39789678 0,4171206 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,40314929 0,42243434 ! activation of MAPK activity GO:0000187 84 59 0,000 0,40314929 0,42224197 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,40314929 0,42204978 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,40314929 0,42185777 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,40835628 0,42711207 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,40835628 0,42691793 ! regulation of heart contraction GO:0008016 91 60 0,000 0,40835628 0,42672396 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,40835628 0,42653017 ! fertilization GO:0009566 68 60 0,000 0,40835628 0,42633656 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,41351813 0,43152981 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,41351813 0,43133411 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,41351813 0,43113858 ! extracellular matrix organization GO:0030198 103 61 0,000 0,41351813 0,43094323 ! amine catabolic process GO:0009310 90 62 0,000 0,41863525 0,43607838 ! neurotransmitter transport GO:0006836 81 62 0,000 0,41863525 0,43588097 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,41863525 0,43568374 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,41863525 0,43548669 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,423708 0,44056438 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,423708 0,4403653 ! viral reproduction GO:0016032 92 63 0,000 0,423708 0,4401664 ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,42873679 0,44518944 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,42873679 0,44498854 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 0,000 0,42873679 0,44478783 ! hexose catabolic process GO:0019320 82 64 0,000 0,42873679 0,44458729 ! B cell activation GO:0042113 104 65 0,000 0,43372198 0,4495541 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,43372198 0,4493516 ! activation of immune response GO:0002253 83 65 0,000 0,43372198 0,44914928 ! protein oligomerization GO:0051259 100 65 0,000 0,43372198 0,44894714 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,43866394 0,45385833 ! antigen processing and presentation GO:0019882 96 66 0,000 0,43866394 0,45365426 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,43866394 0,45345037 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,44356306 0,45830865 ! acute inflammatory response GO:0002526 92 68 0,000 0,44841971 0,46311869 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,44841971 0,46291083 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,44841971 0,46270315 ! inorganic anion transport GO:0015698 93 68 0,000 0,44841971 0,46249566 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,45323423 0,46725179 ! response to drug GO:0042493 108 69 0,000 0,45323423 0,46704245 ! response to metal ion GO:0010038 103 70 0,000 0,45800701 0,47174928 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,45800701 0,47153811 ! amine transport GO:0015837 101 70 0,000 0,45800701 0,47132713 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,45800701 0,47111634 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,4627384 0,47577037 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,4627384 0,47555779 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,4627384 0,47534539 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,4627384 0,47513318 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,47207843 0,48450709 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,47207843 0,48429099 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,47668778 0,48880155 ! digestion GO:0007586 97 74 0,000 0,47668778 0,48858373 ! response to inorganic substance GO:0010035 115 75 0,000 0,48125714 0,4930474 ! response to nutrient GO:0007584 104 75 0,000 0,48125714 0,49282788 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,48125714 0,49260855 ! amine biosynthetic process GO:0009309 97 76 0,000 0,48578686 0,49702392 ! response to unfolded protein GO:0006986 99 76 0,000 0,48578686 0,49680293 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,49027729 0,50117234 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,49027729 0,5009497 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,49027729 0,50072725 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,49027729 0,500505 ! positive regulation of protein modification process GO:0031401 107 78 0,000 0,49472876 0,50482527 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,49472876 0,5046014 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,49472876 0,50437773 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,49914161 0,50865118 ! cellular respiration GO:0045333 107 79 0,000 0,49914161 0,50842591 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,49914161 0,50820084 ! T cell activation GO:0042110 134 79 0,000 0,49914161 0,50797598 ! regulation of lyase activity GO:0051339 133 79 0,000 0,49914161 0,50775131 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,49914161 0,50752684 ! alcohol catabolic process GO:0046164 104 80 0,000 0,50351617 0,51174865 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,50351617 0,51152261 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,50785277 0,51570039 ! response to protein stimulus GO:0051789 111 81 0,000 0,50785277 0,51547281 ! vitamin metabolic process GO:0006766 103 81 0,000 0,50785277 0,51524542 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,51641341 0,52369966 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,51641341 0,52346886 ! sterol metabolic process GO:0016125 120 84 0,000 0,52063808 0,52751876 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,52482609 0,53152797 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,52897775 0,53549685 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,53309338 0,53942577 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,53309338 0,53918855 ! female pregnancy GO:0007565 130 87 0,000 0,53309338 0,53895155 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,53717327 0,54283767 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,53717327 0,54259927 GO:0016054|organic acid catabolic process, ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,54121775 0,54644461 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,54121775 0,54620484 ! leukocyte differentiation GO:0002521 143 90 0,000 0,54522712 0,55000981 ! hormone metabolic process GO:0042445 121 90 0,000 0,54522712 0,54976869 ! ATP metabolic process GO:0046034 137 91 0,000 0,54920168 0,55353368 ! response to virus GO:0009615 122 91 0,000 0,54920168 0,55329122 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,55314172 0,55701662 ! positive regulation of immune response GO:0050778 121 92 0,000 0,55314172 0,55677285 ! DNA recombination GO:0006310 146 92 0,000 0,55314172 0,55652929 ! sulfur metabolic process GO:0006790 118 92 0,000 0,55314172 0,55628595 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,55704756 0,55996913 ! electron transport chain GO:0022900 123 94 0,000 0,56091947 0,56361502 ! response to oxidative stress GO:0006979 141 94 0,000 0,56091947 0,5633689 ! carboxylic acid transport GO:0046942 147 95 0,000 0,56475777 0,56697637 GO:0015849|organic acid transport, ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,56856272 0,57054724 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,57233464 0,57408184 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,57233464 0,57383159 ! calcium ion transport GO:0006816 167 99 0,000 0,57978046 0,5810436 ! regulation of translation GO:0006417 151 100 0,000 0,58345493 0,58447141 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,58345493 0,58421696 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,58345493 0,58396273 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,58345493 0,58370872 ! divalent metal ion transport GO:0070838 171 100 0,000 0,58345493 0,58345493