pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6485-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 4,000 5,574E-07 1,341E-03 ! negative regulation of B cell activation GO:0050869 13 6 2,000 5,517E-06 6,637E-03 ! negative regulation of ligase activity GO:0051352 112 68 5,000 5,837E-06 4,681E-03 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! regulation of protein export from nucleus GO:0046825 10 7 2,000 9,607E-06 5,779E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 3,000 1,208E-05 5,814E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 4,000 1,286E-05 5,156E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 5,000 1,396E-05 4,799E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 1,53E-05 4,601E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,53E-05 4,09E-03 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 1,737E-05 4,18E-03 ! regulation of ligase activity GO:0051340 142 84 5,000 1,987E-05 4,346E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 2,419E-05 4,85E-03 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of lymphocyte activation GO:0051250 53 27 3,000 2,825E-05 5,229E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 3,246E-05 5,579E-03 ! negative regulation of leukocyte activation GO:0002695 56 30 3,000 4,344E-05 6,968E-03 ! regulation of B cell activation GO:0050864 50 30 3,000 4,344E-05 6,532E-03 ! cell cycle arrest GO:0007050 213 100 5,000 5,341E-05 7,559E-03 ! regulation of B cell proliferation GO:0030888 20 12 2,000 5,894E-05 7,878E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 5,894E-05 7,464E-03 GO:0042130|negative regulation of T cell proliferation, ! lung development GO:0030324 144 67 4,000 8,101E-05 9,746E-03 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 4,000 8,101E-05 9,282E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 4,000 8,698E-05 9,512E-03 ! negative regulation of cell activation GO:0050866 65 36 3,000 9,053E-05 9,471E-03 ! cell cycle checkpoint GO:0000075 137 69 4,000 9,328E-05 9,351E-03 ! N-terminal protein amino acid modification GO:0031365 27 14 2,000 9,658E-05 9,295E-03 ! respiratory tube development GO:0030323 150 70 4,000 9,992E-05 9,246E-03 ! mitotic cell cycle checkpoint GO:0007093 76 38 3,000 1,123E-04 0,01000645 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 4,000 1,143E-04 9,821E-03 ! respiratory system development GO:0060541 153 72 4,000 1,143E-04 9,482E-03 ! pituitary gland development GO:0021983 29 15 2,000 1,201E-04 9,635E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 1,471E-04 0,0114204 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of intracellular protein transport GO:0033157 80 42 3,000 1,668E-04 0,0125424 ! negative regulation of cell cycle process GO:0010948 32 17 2,000 1,778E-04 0,01296414 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 1,778E-04 0,01258285 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 1,83E-04 0,01257879 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 2,383E-04 0,01592408 ! embryonic organ morphogenesis GO:0048562 26 19 2,000 2,509E-04 0,01631777 ! regulation of lymphocyte differentiation GO:0045619 81 48 3,000 2,812E-04 0,01780492 ! regulation of mast cell proliferation GO:0070666 81 48 3,000 2,812E-04 0,01734838 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 2,938E-04 0,01767175 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 2,938E-04 0,01724073 ! diencephalon development GO:0021536 34 20 2,000 2,938E-04 0,01683024 ! negative regulation of T cell activation GO:0050868 40 20 2,000 2,938E-04 0,01643884 ! gland development GO:0048732 206 88 4,000 2,94E-04 0,01607519 ! endocrine system development GO:0035270 104 49 3,000 3,046E-04 0,01628807 ! regulation of cell cycle process GO:0010564 149 90 4,000 3,263E-04 0,01706811 ! negative regulation of immune system process GO:0002683 95 50 3,000 3,294E-04 0,01686445 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 3,411E-04 0,01709786 ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 3,556E-04 0,01746313 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 4,000 3,798E-04 0,01827627 GO:0010498|proteasomal protein catabolic process, ! apoptotic nuclear changes GO:0030262 32 22 2,000 3,931E-04 0,01854296 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 3,931E-04 0,01818636 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 2,000 3,931E-04 0,01784322 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 4,19E-04 0,01866749 ! hemoglobin biosynthetic process GO:0042541 7 5 1,000 4,245E-04 0,01856919 ! negative regulation of bone resorption GO:0045779 10 5 1,000 4,245E-04 0,01823759 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 4,245E-04 0,01791764 ! microvillus organization GO:0032528 7 5 1,000 4,245E-04 0,01760871 GO:0030033|microvillus assembly, ! paraxial mesoderm development GO:0048339 14 5 1,000 4,245E-04 0,01731026 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 4,245E-04 0,01702175 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 4,245E-04 0,01674271 ! apoptotic cell clearance GO:0043277 20 5 1,000 4,245E-04 0,01647267 ! lymph vessel development GO:0001945 10 5 1,000 4,245E-04 0,0162112 ! regulation of activin receptor signaling pathway GO:0032925 14 5 1,000 4,245E-04 0,0159579 ! substrate-bound cell migration, cell extension GO:0006930 6 5 1,000 4,245E-04 0,01571239 ! meiotic chromosome segregation GO:0045132 7 5 1,000 4,245E-04 0,01547432 ! negative regulation of macrophage differentiation GO:0045650 6 5 1,000 4,245E-04 0,01524336 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 4,245E-04 0,0150192 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 1,000 4,245E-04 0,01480153 GO:0022011|myelination in the peripheral nervous system, ! stem cell division GO:0017145 11 5 1,000 4,245E-04 0,01459008 GO:0048103|somatic stem cell division, ! interphase GO:0051325 213 98 4,000 4,833E-04 0,01637894 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 5,116E-04 0,01709633 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 3,000 5,452E-04 0,01796813 ! positive regulation of cell migration GO:0030335 126 57 3,000 5,452E-04 0,01772531 ! regulation of intracellular transport GO:0032386 101 57 3,000 5,452E-04 0,01748898 ! myelination GO:0042552 45 25 2,000 5,786E-04 0,01831632 ! myoblast cell fate commitment GO:0048625 16 6 1,000 6,34E-04 0,01980937 ! forebrain regionalization GO:0021871 8 6 1,000 6,34E-04 0,0195554 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 1,000 6,34E-04 0,01930786 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 1,000 6,34E-04 0,01906652 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 1,000 6,34E-04 0,01883113 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 1,000 6,34E-04 0,01860148 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! activation of MAPKKK activity GO:0000185 12 6 1,000 6,34E-04 0,01837736 ! vascular smooth muscle contraction GO:0014829 13 6 1,000 6,34E-04 0,01815859 ! establishment of spindle localization GO:0051293 12 6 1,000 6,34E-04 0,01794496 GO:0051653|spindle localization, ! astrocyte development GO:0014002 15 6 1,000 6,34E-04 0,01773629 ! Schwann cell development GO:0014044 15 6 1,000 6,34E-04 0,01753243 ! regulation of viral transcription GO:0046782 10 6 1,000 6,34E-04 0,0173332 ! ectodermal gut morphogenesis GO:0048567 12 6 1,000 6,34E-04 0,01713844 GO:0007439|ectodermal gut development, ! insulin receptor signaling pathway GO:0008286 64 26 2,000 6,509E-04 0,01740022 ! regulation of chromosome organization GO:0033044 42 27 2,000 7,287E-04 0,01926677 ! regulation of homeostatic process GO:0032844 134 62 3,000 7,505E-04 0,01962654 ! regulation of mitosis GO:0007088 105 63 3,000 7,973E-04 0,02062617 GO:0051783|regulation of nuclear division, ! positive regulation of cell motion GO:0051272 146 64 3,000 8,461E-04 0,02165631 ! negative regulation of cellular catabolic process GO:0031330 12 7 1,000 8,837E-04 0,02238109 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 8,837E-04 0,02214795 ! mRNA stabilization GO:0048255 18 7 1,000 8,837E-04 0,02191962 GO:0043489|RNA stabilization, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 8,837E-04 0,02169595 ! spinal cord patterning GO:0021511 13 7 1,000 8,837E-04 0,0214768 ! spindle checkpoint GO:0031577 15 7 1,000 8,837E-04 0,02126204 ! cranial nerve morphogenesis GO:0021602 11 7 1,000 8,837E-04 0,02105152 ! transcription from RNA polymerase I promoter GO:0006360 13 7 1,000 8,837E-04 0,02084513 ! negative regulation of nuclear division GO:0051784 14 7 1,000 8,837E-04 0,02064275 GO:0045839|negative regulation of mitosis, ! cellular iron ion homeostasis GO:0006879 51 29 2,000 9,016E-04 0,02085751 ! ensheathment of neurons GO:0007272 57 30 2,000 9,969E-04 0,0228437 GO:0008366|axon ensheathment, ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 1,005E-03 0,02281523 ! negative regulation of cell growth GO:0030308 132 67 3,000 1,005E-03 0,02260201 ! negative regulation of kinase activity GO:0033673 131 68 3,000 1,063E-03 0,02367117 ! iron ion homeostasis GO:0055072 54 31 2,000 1,098E-03 0,02424577 ! negative regulation of cell size GO:0045792 134 69 3,000 1,122E-03 0,02454544 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,173E-03 0,02542945 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,173E-03 0,02520241 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,173E-03 0,02497938 ! hemoglobin metabolic process GO:0020027 13 8 1,000 1,173E-03 0,02476026 ! regulation of defense response to virus by virus GO:0050690 18 8 1,000 1,173E-03 0,02454495 ! astrocyte differentiation GO:0048708 18 8 1,000 1,173E-03 0,02433336 ! ER overload response GO:0006983 12 8 1,000 1,173E-03 0,02412538 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,173E-03 0,02392093 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 1,173E-03 0,02371991 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,173E-03 0,02352225 ! Schwann cell differentiation GO:0014037 19 8 1,000 1,173E-03 0,02332785 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 1,173E-03 0,02313664 ! spindle organization GO:0007051 46 32 2,000 1,206E-03 0,02359462 ! peripheral nervous system development GO:0007422 64 32 2,000 1,206E-03 0,02340434 ! negative regulation of transferase activity GO:0051348 140 72 3,000 1,315E-03 0,02531455 ! cell fate specification GO:0001708 52 33 2,000 1,32E-03 0,02521417 ! cell proliferation in forebrain GO:0021846 15 9 1,000 1,502E-03 0,02845236 ! induction of positive chemotaxis GO:0050930 15 9 1,000 1,502E-03 0,02823007 ! cerebral cortex cell migration GO:0021795 15 9 1,000 1,502E-03 0,02801123 ! microtubule bundle formation GO:0001578 21 9 1,000 1,502E-03 0,02779576 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,502E-03 0,02758358 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,502E-03 0,02737461 ! motor axon guidance GO:0008045 16 9 1,000 1,502E-03 0,02716879 ! spinal cord motor neuron differentiation GO:0021522 15 9 1,000 1,502E-03 0,02696604 ! induction of an organ GO:0001759 14 9 1,000 1,502E-03 0,02676629 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 1,502E-03 0,02656948 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 1,502E-03 0,02637554 ! negative regulation of lymphocyte differentiation GO:0045620 19 9 1,000 1,502E-03 0,02618441 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,502E-03 0,02599604 ! odontogenesis GO:0042476 66 35 2,000 1,569E-03 0,02696083 ! telencephalon development GO:0021537 68 35 2,000 1,569E-03 0,02676962 ! embryonic organ development GO:0048568 57 36 2,000 1,703E-03 0,02885811 ! negative regulation of organelle organization GO:0010639 161 78 3,000 1,769E-03 0,02975705 ! negative regulation of DNA binding GO:0043392 68 37 2,000 1,845E-03 0,03081936 ! regulation of protein stability GO:0031647 73 37 2,000 1,845E-03 0,03060681 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 1,845E-03 0,03039717 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,869E-03 0,03059377 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,869E-03 0,03038706 ! smoothened signaling pathway GO:0007224 16 10 1,000 1,869E-03 0,03018312 ! lung alveolus development GO:0048286 26 10 1,000 1,869E-03 0,0299819 ! pathogenesis GO:0009405 13 10 1,000 1,869E-03 0,02978334 ! regulation of bone resorption GO:0045124 25 10 1,000 1,869E-03 0,0295874 ! regulation of B cell differentiation GO:0045577 19 10 1,000 1,869E-03 0,02939402 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,869E-03 0,02920315 ! positive regulation of viral reproduction GO:0048524 18 10 1,000 1,869E-03 0,02901474 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,869E-03 0,02882875 ! localization within membrane GO:0051668 20 10 1,000 1,869E-03 0,02864513 ! nucleus organization GO:0006997 67 38 2,000 1,993E-03 0,03034955 ! mammary gland development GO:0030879 86 39 2,000 2,149E-03 0,03251492 ! regulation of action potential in neuron GO:0019228 73 39 2,000 2,149E-03 0,0323117 ! neuron fate specification GO:0048665 17 11 1,000 2,275E-03 0,03399336 ! telencephalon cell migration GO:0022029 20 11 1,000 2,275E-03 0,03378353 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,275E-03 0,03357627 ! detection of mechanical stimulus GO:0050982 22 11 1,000 2,275E-03 0,03337153 ! blood vessel remodeling GO:0001974 29 11 1,000 2,275E-03 0,03316928 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 2,275E-03 0,03296947 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 2,275E-03 0,03277204 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 2,275E-03 0,03257697 ! ventral spinal cord development GO:0021517 21 11 1,000 2,275E-03 0,03238421 ! negative regulation of proteolysis GO:0045861 25 11 1,000 2,275E-03 0,03219371 ! substrate-bound cell migration GO:0006929 13 11 1,000 2,275E-03 0,03200545 ! vasoconstriction GO:0042310 18 11 1,000 2,275E-03 0,03181937 ! nucleosome positioning GO:0016584 15 11 1,000 2,275E-03 0,03163544 ! regulation of leukocyte migration GO:0002685 26 11 1,000 2,275E-03 0,03145363 ! nitric oxide mediated signal transduction GO:0007263 23 11 1,000 2,275E-03 0,03127389 ! embryonic gut development GO:0048566 15 11 1,000 2,275E-03 0,0310962 ! developmental induction GO:0031128 19 11 1,000 2,275E-03 0,03092052 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of hormone secretion GO:0046883 62 40 2,000 2,312E-03 0,03124835 ! negative regulation of binding GO:0051100 72 40 2,000 2,312E-03 0,03107378 ! negative regulation of growth GO:0045926 155 84 3,000 2,32E-03 0,03101629 ! regulation of T cell proliferation GO:0042129 71 41 2,000 2,482E-03 0,0329973 ! regulation of T cell differentiation GO:0045580 70 41 2,000 2,482E-03 0,032816 ! regulation of protein transport GO:0051223 154 87 3,000 2,636E-03 0,03466152 GO:0070201|regulation of establishment of protein localization, ! regulation of positive chemotaxis GO:0050926 19 12 1,000 2,718E-03 0,03553889 GO:0050927|positive regulation of positive chemotaxis, ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 1,000 2,718E-03 0,03534679 ! focal adhesion formation GO:0048041 35 12 1,000 2,718E-03 0,03515675 ! forebrain cell migration GO:0021885 21 12 1,000 2,718E-03 0,03496875 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 1,000 2,718E-03 0,03478274 ! cranial nerve development GO:0021545 20 12 1,000 2,718E-03 0,03459871 ! histone acetylation GO:0016573 26 12 1,000 2,718E-03 0,03441661 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,718E-03 0,03423642 ! digestive tract morphogenesis GO:0048546 26 12 1,000 2,718E-03 0,0340581 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 2,718E-03 0,03388164 ! regulation of DNA binding GO:0051101 155 88 3,000 2,748E-03 0,03407952 ! glucose transport GO:0015758 65 43 2,000 2,846E-03 0,03511858 ! hexose transport GO:0008645 67 44 2,000 3,04E-03 0,03731607 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 2,000 3,04E-03 0,03712665 ! endocrine pancreas development GO:0031018 22 13 1,000 3,198E-03 0,03886231 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 3,198E-03 0,03866702 ! regulation of mRNA stability GO:0043488 31 13 1,000 3,198E-03 0,03847368 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 3,198E-03 0,03828227 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 3,241E-03 0,0386079 ! cell growth GO:0016049 84 45 2,000 3,241E-03 0,03841772 ! response to insulin stimulus GO:0032868 95 46 2,000 3,451E-03 0,0407005 ! positive regulation of protein transport GO:0051222 72 46 2,000 3,451E-03 0,04050197 ! forebrain development GO:0030900 188 95 3,000 3,62E-03 0,04228596 ! vascular process in circulatory system GO:0003018 80 47 2,000 3,669E-03 0,04264013 ! regulation of mRNA processing GO:0050684 24 14 1,000 3,715E-03 0,04297339 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 3,715E-03 0,04276778 GO:0060675|ureteric bud morphogenesis, ! bone mineralization GO:0030282 17 14 1,000 3,715E-03 0,04256412 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 3,715E-03 0,04236239 ! regulation of RNA stability GO:0043487 32 14 1,000 3,715E-03 0,04216257 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 3,715E-03 0,04196463 ! positive regulation of cell cycle GO:0045787 89 48 2,000 3,894E-03 0,04378427 ! cellular component disassembly GO:0022411 86 48 2,000 3,894E-03 0,04358062 ! activation of caspase activity GO:0006919 84 48 2,000 3,894E-03 0,04337886 ! regulation of protein localization GO:0032880 176 97 3,000 3,901E-03 0,04324842 ! regulation of action potential GO:0001508 95 49 2,000 4,128E-03 0,04556472 ! skeletal muscle tissue development GO:0007519 186 99 3,000 4,195E-03 0,04608844 GO:0060538|skeletal muscle organ development, ! negative regulation of bone remodeling GO:0046851 33 15 1,000 4,268E-03 0,04667793 ! cardiac muscle contraction GO:0060048 26 15 1,000 4,268E-03 0,04646672 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 1,000 4,268E-03 0,04625741 ! response to hexose stimulus GO:0009746 22 15 1,000 4,268E-03 0,04604997 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! mRNA splice site selection GO:0006376 38 15 1,000 4,268E-03 0,04584439 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 4,857E-03 0,05193595 ! activation of MAPKK activity GO:0000186 35 16 1,000 4,857E-03 0,05170615 ! regulation of defense response to virus GO:0050688 27 16 1,000 4,857E-03 0,05147837 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 4,857E-03 0,05125258 GO:0031114|regulation of microtubule depolymerization, ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 4,857E-03 0,05102877 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 4,857E-03 0,05080691 ! biomineral formation GO:0031214 20 16 1,000 4,857E-03 0,05058697 ! response to UV GO:0009411 104 53 2,000 5,15E-03 0,05340454 ! negative regulation of hormone secretion GO:0046888 25 17 1,000 5,481E-03 0,05659496 ! endothelial cell migration GO:0043542 28 17 1,000 5,481E-03 0,0563531 ! glial cell development GO:0021782 27 17 1,000 5,481E-03 0,0561133 ! limbic system development GO:0021761 36 17 1,000 5,481E-03 0,05587553 ! myoblast differentiation GO:0045445 45 17 1,000 5,481E-03 0,05563977 ! cell differentiation in spinal cord GO:0021515 30 17 1,000 5,481E-03 0,05540599 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 5,481E-03 0,05517416 ! regulation of survival gene product expression GO:0045884 33 17 1,000 5,481E-03 0,05494427 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 5,481E-03 0,05471629 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 5,481E-03 0,05449019 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 5,481E-03 0,05426595 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 5,481E-03 0,05404355 ! positive regulation of caspase activity GO:0043280 95 55 2,000 5,712E-03 0,05609452 GO:0010952|positive regulation of peptidase activity, ! regulation of protein catabolic process GO:0042176 116 55 2,000 5,712E-03 0,0558665 ! skeletal muscle fiber development GO:0048741 111 56 2,000 6,007E-03 0,05850884 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 6,139E-03 0,05956085 ! cell-substrate junction assembly GO:0007044 54 18 1,000 6,139E-03 0,05932165 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 6,139E-03 0,05908437 ! nerve development GO:0021675 28 18 1,000 6,139E-03 0,05884897 ! muscle fiber development GO:0048747 112 57 2,000 6,31E-03 0,06024478 ! positive regulation of hormone secretion GO:0046887 32 19 1,000 6,832E-03 0,06497169 ! lipid phosphorylation GO:0046834 35 19 1,000 6,832E-03 0,06471589 ! cerebral cortex development GO:0021987 36 19 1,000 6,832E-03 0,0644621 ! actin filament bundle formation GO:0051017 42 19 1,000 6,832E-03 0,0642103 ! neuromuscular junction development GO:0007528 34 19 1,000 6,832E-03 0,06396045 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 6,832E-03 0,06371254 ! heart process GO:0003015 30 19 1,000 6,832E-03 0,06346655 GO:0060047|heart contraction, ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 6,832E-03 0,06322245 ! proximal/distal pattern formation GO:0009954 32 19 1,000 6,832E-03 0,06298022 ! skeletal system morphogenesis GO:0048705 105 59 2,000 6,944E-03 0,06376624 ! DNA catabolic process GO:0006308 86 59 2,000 6,944E-03 0,06352378 ! establishment of organelle localization GO:0051656 109 59 2,000 6,944E-03 0,06328316 ! camera-type eye development GO:0043010 116 60 2,000 7,274E-03 0,06604578 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 7,274E-03 0,06579749 ! protein amino acid acetylation GO:0006473 39 20 1,000 7,558E-03 0,06811132 ! response to alkaloid GO:0043279 38 20 1,000 7,558E-03 0,06785717 ! pancreas development GO:0031016 35 20 1,000 7,558E-03 0,06760491 ! response to carbohydrate stimulus GO:0009743 29 20 1,000 7,558E-03 0,06735452 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 7,558E-03 0,06710598 ! peptidyl-serine modification GO:0018209 43 20 1,000 7,558E-03 0,06685927 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 1,000 7,558E-03 0,06661436 ! camera-type eye morphogenesis GO:0048593 42 20 1,000 7,558E-03 0,06637125 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 7,614E-03 0,06661671 ! hindlimb morphogenesis GO:0035137 43 21 1,000 8,318E-03 0,07251311 ! ovarian follicle development GO:0001541 35 21 1,000 8,318E-03 0,07225133 ! smooth muscle contraction GO:0006939 46 21 1,000 8,318E-03 0,07199143 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 8,318E-03 0,0717334 ! positive regulation of locomotion GO:0040017 39 21 1,000 8,318E-03 0,07147721 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 8,318E-03 0,07122284 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 8,318E-03 0,07097028 ! gut development GO:0048565 39 21 1,000 8,318E-03 0,0707195 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 9,111E-03 0,07718455 ! regulation of chemotaxis GO:0050920 40 22 1,000 9,111E-03 0,07691373 ! ureteric bud development GO:0001657 43 22 1,000 9,111E-03 0,0766448 ! positive regulation of B cell activation GO:0050871 38 22 1,000 9,111E-03 0,07637774 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 9,111E-03 0,07611254 ! cell projection assembly GO:0030031 120 66 2,000 9,453E-03 0,07869518 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 9,936E-03 0,08243102 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 9,936E-03 0,08214775 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 9,936E-03 0,08186642 ! vesicle targeting GO:0006903 43 23 1,000 9,936E-03 0,08158701 ! regulation of viral reproduction GO:0050792 38 23 1,000 9,936E-03 0,0813095 ! negative regulation of catabolic process GO:0009895 50 23 1,000 9,936E-03 0,08103388 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 2,000 0,01066914 0,08672285 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 0,0107923 0,08742853 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 0,0107923 0,08713514 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 0,0107923 0,08684372 ! spinal cord development GO:0021510 47 24 1,000 0,0107923 0,08655424 ! regulation of behavior GO:0050795 43 24 1,000 0,0107923 0,08626669 ! pallium development GO:0021543 49 24 1,000 0,0107923 0,08598103 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 0,0107923 0,08569727 ! regulation of multi-organism process GO:0043900 36 24 1,000 0,0107923 0,08541537 ! appendage morphogenesis GO:0035107 135 70 2,000 0,01109385 0,08751408 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 2,000 0,0115282 0,09064331 GO:0060173|limb development, ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 0,01168045 0,09154125 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 0,01168045 0,09124403 ! somitogenesis GO:0001756 43 25 1,000 0,01168045 0,09094875 ! vasculogenesis GO:0001570 46 25 1,000 0,01168045 0,09065536 ! regulation of insulin secretion GO:0050796 37 25 1,000 0,01168045 0,09036387 ! regulation of caspase activity GO:0043281 122 72 2,000 0,01197225 0,09232443 ! carbohydrate transport GO:0008643 110 72 2,000 0,01197225 0,09202947 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 2,000 0,01197225 0,09173638 ! axon guidance GO:0007411 139 73 2,000 0,01242601 0,09491107 ! regulation of interferon-gamma production GO:0032649 39 26 1,000 0,01259958 0,09593225 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 0,01259958 0,09562962 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 0,01259958 0,0953289 ! regulation of response to biotic stimulus GO:0002831 44 26 1,000 0,01259958 0,09503007 ! positive regulation of nuclear division GO:0051785 40 26 1,000 0,01259958 0,0947331 GO:0045840|positive regulation of mitosis, ! regulation of transcription factor activity GO:0051090 126 74 2,000 0,01288953 0,09661127 GO:0090046|regulation of transcription regulator activity, ! regulation of endopeptidase activity GO:0052548 125 74 2,000 0,01288953 0,09631124 ! eye development GO:0001654 143 74 2,000 0,01288953 0,09601306 ! organelle localization GO:0051640 136 74 2,000 0,01288953 0,09571673 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 0,01336284 0,09892612 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 0,01354925 0,09999845 ! neuron fate commitment GO:0048663 48 27 1,000 0,01354925 0,09969265 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 0,01354925 0,09938871 ! iron ion transport GO:0006826 59 27 1,000 0,01354925 0,09908661 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 0,01354925 0,09878635 ! protein amino acid acylation GO:0043543 55 27 1,000 0,01354925 0,0984879 ! regulation of catabolic process GO:0009894 161 76 2,000 0,01384595 0,10034146 ! positive regulation of ligase activity GO:0051351 124 77 2,000 0,01433891 0,10360183 ! dendrite development GO:0016358 59 28 1,000 0,01452902 0,10466116 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 0,01452902 0,10434874 ! activation of protein kinase activity GO:0032147 147 79 2,000 0,01535441 0,10994856 ! regulation of peptidase activity GO:0052547 134 79 2,000 0,01535441 0,1096223 ! regulation of peptide secretion GO:0002791 47 29 1,000 0,01553846 0,11060811 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 0,01553846 0,11028183 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 0,01553846 0,10995747 ! tissue homeostasis GO:0001894 48 29 1,000 0,01553846 0,10963502 GO:0048871|multicellular organismal homeostasis, ! protein import into nucleus GO:0006606 158 80 2,000 0,01587701 0,11169615 ! nuclear import GO:0051170 161 81 2,000 0,01640952 0,11510588 ! response to hypoxia GO:0001666 171 81 2,000 0,01640952 0,11477127 ! intracellular protein transmembrane transport GO:0065002 153 81 2,000 0,01640952 0,1144386 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 1,000 0,01657714 0,11527344 ! cell junction assembly GO:0034329 78 30 1,000 0,01657714 0,11494124 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,01657714 0,11461095 ! eye morphogenesis GO:0048592 60 30 1,000 0,01657714 0,11428255 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 0,01695198 0,11653274 ! response to oxygen levels GO:0070482 176 83 2,000 0,01750438 0,1199873 ! ovulation cycle process GO:0022602 49 31 1,000 0,01764464 0,12060514 ! mesoderm formation GO:0001707 69 31 1,000 0,01764464 0,12026349 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 0,01764464 0,11992376 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of transport GO:0051051 153 84 2,000 0,01806675 0,12244677 ! spliceosome assembly GO:0000245 67 32 1,000 0,01874054 0,12665656 ! metanephros development GO:0001656 74 32 1,000 0,01874054 0,12630178 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01874054 0,12594898 ! regulation of axonogenesis GO:0050770 75 32 1,000 0,01874054 0,12559815 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01874054 0,12524926 ! ovulation cycle GO:0042698 51 32 1,000 0,01874054 0,12490231 ! hindbrain development GO:0030902 61 32 1,000 0,01874054 0,12455728 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,01874054 0,12421415 ! mitochondrion organization GO:0007005 148 86 2,000 0,01922143 0,12705152 ! protein localization in nucleus GO:0034504 176 87 2,000 0,01981375 0,1306079 ! protein targeting to membrane GO:0006612 68 33 1,000 0,01986442 0,13058411 ! formation of primary germ layer GO:0001704 72 33 1,000 0,01986442 0,13022829 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01986442 0,12987441 ! establishment of vesicle localization GO:0051650 61 33 1,000 0,01986442 0,12952245 ! glial cell differentiation GO:0010001 63 34 1,000 0,02101586 0,13665991 ! mesoderm morphogenesis GO:0048332 76 34 1,000 0,02101586 0,13629155 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,02101586 0,13592518 ! regulation of cell morphogenesis GO:0022604 215 89 2,000 0,0210284 0,13564167 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,0210284 0,13527899 ! ossification GO:0001503 188 90 2,000 0,02165074 0,13891117 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,02219447 0,14202102 ! negative regulation of secretion GO:0051048 63 35 1,000 0,02219447 0,1416443 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 0,02219447 0,14126958 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,02219447 0,14089684 ! embryonic skeletal system morphogenesis GO:0048704 59 35 1,000 0,02219447 0,14052606 ! female gonad development GO:0008585 58 35 1,000 0,02219447 0,14015722 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,02219447 0,13979032 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,02219447 0,13942533 ! vesicle localization GO:0051648 64 35 1,000 0,02219447 0,13906224 ! bone development GO:0060348 189 91 2,000 0,02228309 0,13925486 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,02339984 0,14585498 ! cell junction organization GO:0034330 86 36 1,000 0,02339984 0,14547809 ! regulation of proteolysis GO:0030162 72 36 1,000 0,02339984 0,14510315 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 0,02339984 0,14473014 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 0,02357782 0,14545703 ! regulation of membrane potential GO:0042391 164 93 2,000 0,02357782 0,14508502 ! transcription initiation GO:0006352 153 94 2,000 0,0242402 0,14878042 ! regulation of T cell activation GO:0050863 158 94 2,000 0,0242402 0,14840184 ! meiosis I GO:0007127 65 37 1,000 0,02463157 0,15041515 ! sister chromatid segregation GO:0000819 58 37 1,000 0,02463157 0,15003435 ! tissue remodeling GO:0048771 76 37 1,000 0,02463157 0,14965547 ! glycogen metabolic process GO:0005977 61 37 1,000 0,02463157 0,14927851 ! mRNA transport GO:0051028 169 96 2,000 0,02559496 0,15472734 ! regulation of neuron projection development GO:0010975 91 38 1,000 0,02588927 0,15611425 ! carbohydrate homeostasis GO:0033500 53 38 1,000 0,02588927 0,15572397 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,02588927 0,15533563 GO:0046660|female sex differentiation, ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,02588927 0,15494922 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 0,02588927 0,15456473 ! glucan metabolic process GO:0044042 62 38 1,000 0,02588927 0,15418214 GO:0006073|cellular glucan metabolic process, ! learning GO:0007612 77 39 1,000 0,02717254 0,16142503 ! ear morphogenesis GO:0042471 60 39 1,000 0,02717254 0,16102743 ! segmentation GO:0035282 67 39 1,000 0,02717254 0,16063179 ! cytokinesis GO:0000910 72 40 1,000 0,028481 0,16795415 ! gliogenesis GO:0042063 88 41 1,000 0,02981427 0,17538662 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,02981427 0,17495885 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,03117196 0,1824811 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,03117196 0,18203818 ! regulation of tube size GO:0035150 71 42 1,000 0,03117196 0,18159741 GO:0050880|regulation of blood vessel size, ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,03117196 0,18115877 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,03244454 0,18810013 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,03244454 0,18764797 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03244454 0,18719797 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,03244454 0,18675013 ! neuron fate determination GO:0048664 7 5 0,000 0,03244454 0,18630443 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03244454 0,18586084 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,03244454 0,18541937 ! polyol transport GO:0015791 12 5 0,000 0,03244454 0,18497999 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,03244454 0,18454268 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03244454 0,18410744 ! response to superoxide GO:0000303 10 5 0,000 0,03244454 0,18367425 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,03244454 0,18324309 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,03244454 0,18281395 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03244454 0,18238681 ! female meiosis GO:0007143 7 5 0,000 0,03244454 0,18196167 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,03244454 0,1815385 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03244454 0,1811173 ! cobalt ion transport GO:0006824 11 5 0,000 0,03244454 0,18069804 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,03244454 0,18028073 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,03244454 0,17986533 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,03244454 0,17945185 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03244454 0,17904026 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,03244454 0,17863056 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,03244454 0,17822273 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,03244454 0,17781675 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03244454 0,17741262 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,03244454 0,17701033 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,03244454 0,17660985 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03244454 0,17621118 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03244454 0,17581431 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,03244454 0,17541922 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,03244454 0,17502591 ! negative chemotaxis GO:0050919 14 5 0,000 0,03244454 0,17463435 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03244454 0,17424454 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03244454 0,17385647 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,03244454 0,17347012 ! behavioral response to pain GO:0048266 9 5 0,000 0,03244454 0,17308549 ! clathrin coat assembly GO:0048268 14 5 0,000 0,03244454 0,17270255 ! Notch receptor processing GO:0007220 8 5 0,000 0,03244454 0,17232131 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03244454 0,17194175 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,03244454 0,17156386 ! micturition GO:0060073 9 5 0,000 0,03244454 0,17118762 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03244454 0,17081303 ! copulation GO:0007620 9 5 0,000 0,03244454 0,17044008 ! glial cell fate commitment GO:0021781 13 5 0,000 0,03244454 0,17006875 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,03244454 0,16969903 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03244454 0,16933092 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03244454 0,1689644 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03244454 0,16859947 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03244454 0,16823611 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03244454 0,16787431 ! grooming behavior GO:0007625 6 5 0,000 0,03244454 0,16751407 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,03244454 0,16715536 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,03244454 0,16679819 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03244454 0,16644255 ! response to protozoan GO:0001562 10 5 0,000 0,03244454 0,16608841 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,03244454 0,16573578 ! endochondral ossification GO:0001958 16 5 0,000 0,03244454 0,16538465 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03244454 0,165035 ! parathyroid gland development GO:0060017 13 5 0,000 0,03244454 0,16468682 ! anagen GO:0042640 6 5 0,000 0,03244454 0,16434012 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,03244454 0,16399486 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,03244454 0,16365106 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,03244454 0,16330869 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,03244454 0,16296776 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,03244454 0,16262824 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,03244454 0,16229013 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,03244454 0,16195343 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,03244454 0,16161813 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,03244454 0,1612842 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03244454 0,16095166 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03244454 0,16062048 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,03244454 0,16029067 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,03244454 0,1599622 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,03244454 0,15963508 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03244454 0,1593093 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,03244454 0,15898484 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,03244454 0,1586617 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,03244454 0,15833987 ! histidine catabolic process GO:0006548 6 5 0,000 0,03244454 0,15801934 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03244454 0,15770011 ! valine metabolic process GO:0006573 10 5 0,000 0,03244454 0,15738217 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,03244454 0,1570655 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03244454 0,15675011 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,03244454 0,15643598 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,03244454 0,15612311 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03244454 0,15581149 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,03244454 0,1555011 ! polyol catabolic process GO:0046174 7 5 0,000 0,03244454 0,15519196 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03244454 0,15488404 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03244454 0,15457734 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03244454 0,15427185 ! muscle cell migration GO:0014812 8 5 0,000 0,03244454 0,15396756 ! mitochondrial fission GO:0000266 8 5 0,000 0,03244454 0,15366448 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,03244454 0,15336258 ! mRNA transcription GO:0009299 9 5 0,000 0,03244454 0,15306187 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,03244454 0,15276234 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,03244454 0,15246397 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,03244454 0,15216677 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03244454 0,15187073 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,03244454 0,15157583 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03244454 0,15128208 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03244454 0,15098947 ! response to food GO:0032094 6 5 0,000 0,03244454 0,15069798 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,03244454 0,15040762 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03244454 0,15011837 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,03244454 0,14983024 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03244454 0,14954321 ! forebrain neuron development GO:0021884 13 5 0,000 0,03244454 0,14925727 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03244454 0,14897243 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03244454 0,14868868 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,03244454 0,148406 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,03244454 0,14812439 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03244454 0,14784385 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,03244454 0,14756438 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,03244454 0,14728595 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03244454 0,14700858 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,03244454 0,14673225 ! basic amino acid transport GO:0015802 11 5 0,000 0,03244454 0,14645695 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03244454 0,14618269 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,03244454 0,14590945 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03244454 0,14563723 ! depyrimidination GO:0045008 10 5 0,000 0,03244454 0,14536602 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,03244454 0,14509583 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03244454 0,14482663 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,03244454 0,14455843 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,03244454 0,14429123 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,03244454 0,14402501 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03244454 0,14375977 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03244454 0,1434955 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03244454 0,14323221 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,03244454 0,14296988 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,03244454 0,14270851 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03244454 0,14244809 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03244454 0,14218862 ! response to arsenic GO:0046685 10 5 0,000 0,03244454 0,1419301 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,03244454 0,14167251 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,03244454 0,14141586 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,03244454 0,14116014 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,03244454 0,14090533 ! response to cadmium ion GO:0046686 7 5 0,000 0,03244454 0,14065145 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,03244454 0,14039848 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,03244454 0,14014642 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03244454 0,13989526 ! decidualization GO:0046697 11 5 0,000 0,03244454 0,139645 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,03244454 0,13939563 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,03244454 0,13914716 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03244454 0,13889956 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03244454 0,13865285 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,03244454 0,13840701 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03244454 0,13816204 ! neural tube patterning GO:0021532 7 5 0,000 0,03244454 0,13791794 ! embryonic cleavage GO:0040016 6 5 0,000 0,03244454 0,1376747 ! peroxisome fission GO:0016559 5 5 0,000 0,03244454 0,13743231 ! histone demethylation GO:0016577 10 5 0,000 0,03244454 0,13719078 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,03244454 0,1369501 ! mitotic recombination GO:0006312 9 5 0,000 0,03244454 0,13671025 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03244454 0,13647125 ! metaphase plate congression GO:0051310 7 5 0,000 0,03244454 0,13623308 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03244454 0,13599574 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,03244454 0,13575923 ! enteric nervous system development GO:0048484 8 5 0,000 0,03244454 0,13552353 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,03244454 0,13528866 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,03244454 0,13505459 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,03244454 0,13482134 ! muscle cell proliferation GO:0033002 11 5 0,000 0,03244454 0,13458889 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03244454 0,13435724 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,03244454 0,13412638 ! plasminogen activation GO:0031639 5 5 0,000 0,03244454 0,13389632 ! B cell homeostasis GO:0001782 13 5 0,000 0,03244454 0,13366705 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,03244454 0,13343856 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03244454 0,13321084 ! metaphase GO:0051323 8 5 0,000 0,03244454 0,13298391 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,03244454 0,13275775 ! cellular response to nutrient GO:0031670 8 5 0,000 0,03244454 0,13253235 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03244454 0,13230772 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03244454 0,13208385 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03244454 0,13186073 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,03244454 0,13163837 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,03244454 0,13141676 ! response to redox state GO:0051775 5 5 0,000 0,03244454 0,13119589 GO:0006980|redox signal response, ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,03244454 0,13097576 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,03244454 0,13075637 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,03244454 0,13053772 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03244454 0,13031979 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,03244454 0,13010259 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03244454 0,12988611 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,03244454 0,12967036 ! striatum development GO:0021756 9 5 0,000 0,03244454 0,12945531 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,03244454 0,12924098 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,03244454 0,12902736 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03244454 0,12881445 ! glial cell migration GO:0008347 11 5 0,000 0,03244454 0,12860223 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,03244454 0,12839071 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,03244454 0,12817989 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03244454 0,12796976 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03244454 0,12776032 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,03244454 0,12755156 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03244454 0,12734348 ! neuroprotection GO:0043526 6 5 0,000 0,03244454 0,12713608 ! neural plate development GO:0001840 8 5 0,000 0,03244454 0,12692936 ! regulation of sensory perception GO:0051931 7 5 0,000 0,03244454 0,1267233 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03244454 0,12651792 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,03244454 0,1263132 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,03244454 0,12610914 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,03244454 0,12590573 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03244454 0,12570299 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03244454 0,12550089 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03244454 0,12529945 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03244454 0,12509865 ! spindle assembly GO:0051225 6 5 0,000 0,03244454 0,12489849 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,03244454 0,12469897 GO:0016226|iron-sulfur cluster assembly, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,03244454 0,12450009 ! drug metabolic process GO:0017144 6 5 0,000 0,03244454 0,12430184 ! phospholipid scrambling GO:0017121 8 5 0,000 0,03244454 0,12410422 ! organ regeneration GO:0031100 7 5 0,000 0,03244454 0,12390723 ! carnitine metabolic process GO:0009437 7 5 0,000 0,03244454 0,12371086 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,03244454 0,12351512 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03244454 0,12331999 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,0325537 0,12353975 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,0325537 0,1233452 ! neural tube development GO:0021915 77 43 1,000 0,0325537 0,12315126 ! striated muscle contraction GO:0006941 77 43 1,000 0,0325537 0,12295793 ! phagocytosis GO:0006909 90 43 1,000 0,0325537 0,1227652 ! developmental growth GO:0048589 82 44 1,000 0,03395912 0,12786485 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,03538785 0,1330362 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,03538785 0,13282865 ! pigmentation GO:0043473 100 46 1,000 0,03683953 0,13806216 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,0383138 0,14336391 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,0383138 0,14314129 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03880665 0,14475783 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03880665 0,14453375 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03880665 0,14431036 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03880665 0,14408766 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03880665 0,14386564 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03880665 0,14364431 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03880665 0,14342366 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03880665 0,14320368 ! sleep GO:0030431 13 6 0,000 0,03880665 0,14298438 ! response to oxygen radical GO:0000305 11 6 0,000 0,03880665 0,14276575 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03880665 0,14254779 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03880665 0,14233049 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03880665 0,14211385 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03880665 0,14189787 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03880665 0,14168255 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03880665 0,14146788 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03880665 0,14125386 ! male meiosis GO:0007140 7 6 0,000 0,03880665 0,14104049 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03880665 0,14082775 ! response to zinc ion GO:0010043 9 6 0,000 0,03880665 0,14061566 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03880665 0,14040421 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03880665 0,1401934 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03880665 0,13998321 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03880665 0,13977365 ! malate metabolic process GO:0006108 11 6 0,000 0,03880665 0,13956473 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03880665 0,13935642 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03880665 0,13914874 ! protein refolding GO:0042026 15 6 0,000 0,03880665 0,13894167 ! opsonization GO:0008228 8 6 0,000 0,03880665 0,13873522 ! mating behavior GO:0007617 7 6 0,000 0,03880665 0,13852938 ! neuron remodeling GO:0016322 15 6 0,000 0,03880665 0,13832415 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03880665 0,13811953 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03880665 0,13791551 ! equilibrioception GO:0050957 14 6 0,000 0,03880665 0,1377121 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03880665 0,13750928 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03880665 0,13730706 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03880665 0,13710544 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03880665 0,1369044 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03880665 0,13670396 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03880665 0,1365041 ! toxin metabolic process GO:0009404 11 6 0,000 0,03880665 0,13630482 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03880665 0,13610612 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03880665 0,13590801 ! nuclear migration GO:0007097 12 6 0,000 0,03880665 0,13571047 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03880665 0,1355135 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03880665 0,1353171 ! thymic T cell selection GO:0045061 12 6 0,000 0,03880665 0,13512128 ! protein lipoylation GO:0009249 10 6 0,000 0,03880665 0,13492601 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03880665 0,13473132 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03880665 0,13453718 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03880665 0,1343436 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03880665 0,13415058 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03880665 0,13395811 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03880665 0,13376619 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03880665 0,13357482 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03880665 0,133384 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03880665 0,13319373 ! hyperosmotic response GO:0006972 9 6 0,000 0,03880665 0,13300399 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03880665 0,1328148 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03880665 0,13262614 ! urea metabolic process GO:0019627 7 6 0,000 0,03880665 0,13243802 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03880665 0,13225043 ! neutrophil activation GO:0042119 8 6 0,000 0,03880665 0,13206337 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03880665 0,13187684 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03880665 0,13169083 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03880665 0,13150535 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03880665 0,1313204 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03880665 0,13113596 ! neuron apoptosis GO:0051402 9 6 0,000 0,03880665 0,13095204 ! nucleoside salvage GO:0043174 9 6 0,000 0,03880665 0,13076863 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03880665 0,13058574 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03880665 0,13040335 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03880665 0,13022148 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03880665 0,13004011 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,03880665 0,12985925 ! carnitine transport GO:0015879 10 6 0,000 0,03880665 0,12967889 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03880665 0,12949903 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03880665 0,12931967 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03880665 0,1291408 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03880665 0,12896243 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03880665 0,12878455 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03880665 0,12860716 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03880665 0,12843026 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03880665 0,12825385 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03880665 0,12807792 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03880665 0,12790247 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03880665 0,1277275 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03880665 0,12755301 ! neural nucleus development GO:0048857 14 6 0,000 0,03880665 0,12737899 ! response to UV-C GO:0010225 11 6 0,000 0,03880665 0,12720545 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03880665 0,12703238 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03880665 0,12685978 ! interaction with symbiont GO:0051702 13 6 0,000 0,03880665 0,12668765 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03880665 0,12651599 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03880665 0,12634479 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03880665 0,12617406 ! response to copper ion GO:0046688 10 6 0,000 0,03880665 0,12600378 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03880665 0,12583396 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03880665 0,1256646 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03880665 0,1254957 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03880665 0,12532725 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03880665 0,12515925 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03880665 0,1249917 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03880665 0,1248246 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03880665 0,12465795 ! hair follicle maturation GO:0048820 7 6 0,000 0,03880665 0,12449174 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03880665 0,12432597 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03880665 0,12416064 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03880665 0,12399575 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03880665 0,1238313 ! subpallium development GO:0021544 10 6 0,000 0,03880665 0,12366729 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03880665 0,12350371 ! histone ubiquitination GO:0016574 8 6 0,000 0,03880665 0,12334056 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03880665 0,12317784 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03880665 0,12301555 ! G2 phase GO:0051319 16 6 0,000 0,03880665 0,12285369 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03880665 0,12269225 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03880665 0,12253124 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03880665 0,12237064 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03880665 0,12221047 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03880665 0,12205072 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03880665 0,12189139 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03880665 0,12173247 ! receptor internalization GO:0031623 10 6 0,000 0,03880665 0,12157396 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03880665 0,12141587 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03880665 0,12125818 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03880665 0,12110091 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03880665 0,12094404 ! protein deubiquitination GO:0016579 14 6 0,000 0,03880665 0,12078758 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03880665 0,12063153 ! protein destabilization GO:0031648 9 6 0,000 0,03880665 0,12047587 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03880665 0,12032062 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03880665 0,12016577 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03880665 0,12001131 GO:0045625|regulation of T-helper 1 cell differentiation, ! progesterone metabolic process GO:0042448 10 6 0,000 0,03880665 0,11985725 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03880665 0,11970359 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03880665 0,11955032 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03880665 0,11939744 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03880665 0,11924496 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03880665 0,11909286 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03880665 0,11894115 ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03880665 0,11878982 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03880665 0,11863888 ! catecholamine transport GO:0051937 9 6 0,000 0,03880665 0,11848833 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03880665 0,11833815 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03880665 0,11818836 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03880665 0,11803894 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03880665 0,1178899 ! maternal placenta development GO:0001893 12 6 0,000 0,03880665 0,11774124 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03880665 0,11759295 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03880665 0,11744503 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03880665 0,11729749 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03880665 0,11715032 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03880665 0,11700351 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03880665 0,11685707 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,03981029 0,11972945 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,04132867 0,12414079 ! ribonucleoprotein complex assembly GO:0022618 95 49 1,000 0,04132867 0,123986 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,04132867 0,1238316 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,04286857 0,1282858 ! histone modification GO:0016570 91 50 1,000 0,04286857 0,12812644 ! positive regulation of binding GO:0051099 78 51 1,000 0,04442966 0,1326275 ! embryonic skeletal system development GO:0048706 85 51 1,000 0,04442966 0,13246315 ! chromatin remodeling GO:0006338 109 51 1,000 0,04442966 0,13229921 ! regulation of cell shape GO:0008360 125 51 1,000 0,04442966 0,13213568 ! epithelial tube morphogenesis GO:0060562 98 51 1,000 0,04442966 0,13197254 ! tRNA transcription GO:0009304 14 7 0,000 0,04512714 0,13387904 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04512714 0,13371416 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,04512714 0,13354969 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04512714 0,13338563 ! regulation of helicase activity GO:0051095 15 7 0,000 0,04512714 0,13322196 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,04512714 0,1330587 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04512714 0,13289584 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04512714 0,13273338 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04512714 0,13257131 ! prostate gland development GO:0030850 13 7 0,000 0,04512714 0,13240964 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04512714 0,13224836 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04512714 0,13208747 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04512714 0,13192698 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04512714 0,13176687 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04512714 0,13160715 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04512714 0,13144782 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04512714 0,13128888 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,04512714 0,13113032 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04512714 0,13097214 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04512714 0,13081434 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04512714 0,13065692 ! glycolipid transport GO:0046836 10 7 0,000 0,04512714 0,13049988 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04512714 0,13034322 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,04512714 0,13018693 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04512714 0,13003102 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04512714 0,12987548 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04512714 0,12972031 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04512714 0,12956551 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04512714 0,12941109 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04512714 0,12925703 ! pericardium development GO:0060039 14 7 0,000 0,04512714 0,12910333 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04512714 0,12895 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04512714 0,12879704 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,04512714 0,12864443 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04512714 0,12849219 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04512714 0,12834031 ! lipoprotein transport GO:0042953 14 7 0,000 0,04512714 0,12818879 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04512714 0,12803762 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04512714 0,12788681 ! rhythmic behavior GO:0007622 15 7 0,000 0,04512714 0,12773635 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04512714 0,12758625 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04512714 0,1274365 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04512714 0,12728711 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04512714 0,12713806 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04512714 0,12698936 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04512714 0,12684101 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04512714 0,126693 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04512714 0,12654534 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04512714 0,12639802 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04512714 0,12625105 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04512714 0,12610441 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04512714 0,12595812 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04512714 0,12581217 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04512714 0,12566655 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04512714 0,12552127 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04512714 0,12537633 ! adrenal gland development GO:0030325 17 7 0,000 0,04512714 0,12523172 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04512714 0,12508744 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04512714 0,1249435 ! ovulation GO:0030728 9 7 0,000 0,04512714 0,12479989 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04512714 0,1246566 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04512714 0,12451365 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04512714 0,12437102 ! microtubule nucleation GO:0007020 20 7 0,000 0,04512714 0,12422872 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04512714 0,12408674 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04512714 0,12394509 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04512714 0,12380376 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04512714 0,12366276 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04512714 0,12352207 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04512714 0,12338171 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04512714 0,12324166 ! galactose metabolic process GO:0006012 13 7 0,000 0,04512714 0,12310193 ! vesicle fusion GO:0006906 17 7 0,000 0,04512714 0,12296252 ! response to dietary excess GO:0002021 8 7 0,000 0,04512714 0,12282342 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04512714 0,12268463 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04512714 0,12254616 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04512714 0,12240801 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04512714 0,12227016 ! organ growth GO:0035265 15 7 0,000 0,04512714 0,12213262 ! purine salvage GO:0043101 10 7 0,000 0,04512714 0,12199539 ! nucleoside transport GO:0015858 8 7 0,000 0,04512714 0,12185847 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04512714 0,12172186 ! parturition GO:0007567 14 7 0,000 0,04512714 0,12158556 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,04512714 0,12144955 ! rRNA modification GO:0000154 14 7 0,000 0,04512714 0,12131386 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04512714 0,12117846 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,04512714 0,12104337 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04512714 0,12090858 ! macrophage differentiation GO:0030225 11 7 0,000 0,04512714 0,12077408 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04512714 0,12063989 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04512714 0,12050599 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,04512714 0,1203724 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04512714 0,12023909 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,04512714 0,12010609 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04512714 0,11997337 ! fibrinolysis GO:0042730 10 7 0,000 0,04512714 0,11984095 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,04512714 0,11970882 ! eating behavior GO:0042755 7 7 0,000 0,04512714 0,11957698 ! B cell lineage commitment GO:0002326 21 7 0,000 0,04512714 0,11944544 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04512714 0,11931418 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04512714 0,11918321 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04512714 0,11905252 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04512714 0,11892213 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04512714 0,11879201 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04512714 0,11866219 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04512714 0,11853264 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04512714 0,11840338 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04512714 0,1182744 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04512714 0,1181457 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04512714 0,11801728 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04512714 0,11788914 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04512714 0,11776128 ! regulation of meiosis GO:0040020 12 7 0,000 0,04512714 0,1176337 GO:0051445|regulation of meiotic cell cycle, ! T cell lineage commitment GO:0002360 16 7 0,000 0,04512714 0,11750639 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04512714 0,11737935 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04512714 0,11725259 ! oxygen homeostasis GO:0032364 12 7 0,000 0,04512714 0,11712611 ! transcription termination GO:0006353 13 7 0,000 0,04512714 0,11699989 ! response to tumor cell GO:0002347 13 7 0,000 0,04512714 0,11687395 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,04512714 0,11674828 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04512714 0,11662288 ! anaphase GO:0051322 17 7 0,000 0,04512714 0,11649775 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04512714 0,11637288 ! axonal fasciculation GO:0007413 18 7 0,000 0,04512714 0,11624829 ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04512714 0,11612396 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,04512714 0,11599989 ! diuresis GO:0030146 12 7 0,000 0,04512714 0,1158761 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04512714 0,11575256 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04512714 0,11562929 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04512714 0,11550628 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,04512714 0,11538353 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,04512714 0,11526104 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04512714 0,11513881 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04512714 0,11501684 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04512714 0,11489513 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04512714 0,11477368 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04512714 0,11465248 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04512714 0,11453154 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04512714 0,11441085 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04512714 0,11429042 ! lymph node development GO:0048535 10 7 0,000 0,04512714 0,11417024 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04512714 0,11405032 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04512714 0,11393064 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04512714 0,11381122 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04512714 0,11369204 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04512714 0,11357312 ! adult feeding behavior GO:0008343 9 7 0,000 0,04512714 0,11345444 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04512714 0,11333601 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04512714 0,11321783 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04512714 0,1130999 ! muscle adaptation GO:0043500 14 7 0,000 0,04512714 0,11298221 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04512714 0,11286476 ! retina homeostasis GO:0001895 12 7 0,000 0,04512714 0,11274756 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04512714 0,1126306 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04512714 0,11251389 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04512714 0,11239741 ! protein prenylation GO:0018342 18 7 0,000 0,04512714 0,11228118 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04512714 0,11216519 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04512714 0,11204943 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04512714 0,11193392 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,04601159 0,11401018 ! positive regulation of growth GO:0045927 90 52 1,000 0,04601159 0,11389288 ! covalent chromatin modification GO:0016569 101 52 1,000 0,04601159 0,11377583 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,04601159 0,11365902 ! amino acid activation GO:0043038 92 52 1,000 0,04601159 0,11354244 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 1,000 0,04601159 0,11342611 ! synapse organization GO:0050808 85 52 1,000 0,04601159 0,11331001 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,04923662 0,12112813 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,04923662 0,1210044 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,04923662 0,12088093 GO:0010863|positive regulation of phospholipase C activity, ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,05087906 0,12478595 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,05087906 0,12465888 ! aging GO:0007568 103 55 1,000 0,05087906 0,12453206 ! gastrulation GO:0007369 112 55 1,000 0,05087906 0,1244055 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,05087906 0,1242792 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,05140628 0,12543966 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,05140628 0,12531257 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,05140628 0,12518573 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,05140628 0,12505916 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,05140628 0,12493283 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,05140628 0,12480677 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,05140628 0,12468095 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,05140628 0,12455539 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,05140628 0,12443009 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,05140628 0,12430503 ! meiotic prophase I GO:0007128 13 8 0,000 0,05140628 0,12418023 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,05140628 0,12405567 ! oligopeptide transport GO:0006857 15 8 0,000 0,05140628 0,12393137 ! UTP metabolic process GO:0046051 8 8 0,000 0,05140628 0,12380731 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,05140628 0,12368351 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,05140628 0,12355995 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,05140628 0,12343663 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,05140628 0,12331356 ! succinate metabolic process GO:0006105 14 8 0,000 0,05140628 0,12319074 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,05140628 0,12306816 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,05140628 0,12294583 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,05140628 0,12282374 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,05140628 0,12270189 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05140628 0,12258028 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,05140628 0,12245892 ! reflex GO:0060004 16 8 0,000 0,05140628 0,12233779 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,05140628 0,1222169 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,05140628 0,12209625 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,05140628 0,12197584 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,05140628 0,12185567 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,05140628 0,12173573 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,05140628 0,12161603 ! pigment granule organization GO:0048753 16 8 0,000 0,05140628 0,12149657 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,05140628 0,12137734 ! histidine metabolic process GO:0006547 16 8 0,000 0,05140628 0,12125834 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,05140628 0,12113957 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,05140628 0,12102104 ! glycine catabolic process GO:0006546 13 8 0,000 0,05140628 0,12090274 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,05140628 0,12078467 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,05140628 0,12066683 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,05140628 0,12054923 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,05140628 0,12043185 ! melanin metabolic process GO:0006582 15 8 0,000 0,05140628 0,12031469 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,05140628 0,12019777 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,05140628 0,12008107 ! macrophage activation GO:0042116 12 8 0,000 0,05140628 0,1199646 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,05140628 0,11984836 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,05140628 0,11973234 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,05140628 0,11961654 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,05140628 0,11950097 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,05140628 0,11938562 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,05140628 0,1192705 ! osteoblast development GO:0002076 16 8 0,000 0,05140628 0,11915559 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,05140628 0,11904091 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,05140628 0,11892645 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,05140628 0,11881221 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,05140628 0,11869818 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,05140628 0,11858438 ! response to UV-B GO:0010224 16 8 0,000 0,05140628 0,11847079 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,05140628 0,11835742 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,05140628 0,11824427 ! intermediate filament organization GO:0045109 12 8 0,000 0,05140628 0,11813133 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,05140628 0,11801861 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,05140628 0,11790611 ! cellular extravasation GO:0045123 12 8 0,000 0,05140628 0,11779381 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,05140628 0,11768174 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,05140628 0,11756987 ! response to antibiotic GO:0046677 11 8 0,000 0,05140628 0,11745822 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,05140628 0,11734678 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,05140628 0,11723555 ! DNA topological change GO:0006265 12 8 0,000 0,05140628 0,11712453 ! response to tropane GO:0014073 15 8 0,000 0,05140628 0,11701372 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,05140628 0,11690312 ! melanosome transport GO:0032402 13 8 0,000 0,05140628 0,11679273 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,05140628 0,11668255 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,05140628 0,11657258 ! mast cell activation GO:0045576 14 8 0,000 0,05140628 0,11646281 ! multicellular organismal aging GO:0010259 18 8 0,000 0,05140628 0,11635325 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,05140628 0,1162439 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,05140628 0,11613475 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,05140628 0,1160258 ! nucleosome disassembly GO:0006337 14 8 0,000 0,05140628 0,11591706 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,05140628 0,11580853 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,05140628 0,11570019 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,05140628 0,11559206 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,05140628 0,11548413 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,05140628 0,1153764 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,05140628 0,11526888 ! intracellular lipid transport GO:0032365 13 8 0,000 0,05140628 0,11516155 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,05140628 0,11505442 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,05140628 0,1149475 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,05140628 0,11484077 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,05140628 0,11473424 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,05140628 0,1146279 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,05140628 0,11452176 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,05140628 0,11441582 ! hormone catabolic process GO:0042447 17 8 0,000 0,05140628 0,11431008 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,05140628 0,11420453 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,05140628 0,11409917 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,05140628 0,11399401 ! ATP catabolic process GO:0006200 11 8 0,000 0,05140628 0,11388905 ! blastocyst growth GO:0001832 19 8 0,000 0,05140628 0,11378427 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,05140628 0,11367969 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,05140628 0,1135753 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,05140628 0,11347111 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,05140628 0,1133671 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,05140628 0,11326328 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,05140628 0,11315966 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,05140628 0,11305622 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,05140628 0,11295297 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,05140628 0,11284991 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,05140628 0,11274704 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,05140628 0,11264436 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,05140628 0,11254186 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,05140628 0,11243955 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,05140628 0,11233743 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,05140628 0,11223549 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,05140628 0,11213373 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,052541 0,11450512 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,05422213 0,11806195 ! lipid modification GO:0030258 97 57 1,000 0,05422213 0,1179552 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,05422213 0,11784865 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,05592213 0,12143379 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,05592213 0,12132429 ! positive regulation of secretion GO:0051047 95 59 1,000 0,05764067 0,12494004 ! regulation of developmental growth GO:0048638 15 9 0,000 0,05764433 0,12483552 ! axon extension GO:0048675 15 9 0,000 0,05764433 0,12472326 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05764433 0,1246112 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,05764433 0,12449934 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05764433 0,12438768 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05764433 0,12427622 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05764433 0,12416496 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05764433 0,1240539 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05764433 0,12394304 ! phosphate transport GO:0006817 19 9 0,000 0,05764433 0,12383238 ! reproductive behavior GO:0019098 19 9 0,000 0,05764433 0,12372191 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05764433 0,12361164 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05764433 0,12350157 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05764433 0,12339169 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05764433 0,12328201 ! GTP metabolic process GO:0046039 9 9 0,000 0,05764433 0,12317252 ! RNA methylation GO:0001510 15 9 0,000 0,05764433 0,12306323 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05764433 0,12295413 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05764433 0,12284523 ! artery development GO:0060840 24 9 0,000 0,05764433 0,12273652 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05764433 0,122628 ! regulation of glycolysis GO:0006110 21 9 0,000 0,05764433 0,12251967 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05764433 0,12241153 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05764433 0,12230358 ! chemosensory behavior GO:0007635 20 9 0,000 0,05764433 0,12219583 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05764433 0,12208826 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05764433 0,12198088 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05764433 0,12187369 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05764433 0,12176669 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05764433 0,12165988 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05764433 0,12155325 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05764433 0,12144681 ! protein targeting to ER GO:0045047 22 9 0,000 0,05764433 0,12134056 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05764433 0,1212345 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05764433 0,12112861 ! T cell selection GO:0045058 23 9 0,000 0,05764433 0,12102292 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05764433 0,1209174 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05764433 0,12081208 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05764433 0,12070693 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05764433 0,12060197 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05764433 0,12049719 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05764433 0,12039259 ! mannose metabolic process GO:0006013 13 9 0,000 0,05764433 0,12028817 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05764433 0,12018394 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05764433 0,12007988 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05764433 0,11997601 ! receptor clustering GO:0043113 18 9 0,000 0,05764433 0,11987231 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05764433 0,11976879 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05764433 0,11966546 ! ruffle organization GO:0031529 15 9 0,000 0,05764433 0,1195623 ! retinol metabolic process GO:0042572 18 9 0,000 0,05764433 0,11945931 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05764433 0,11935651 ! behavioral fear response GO:0001662 22 9 0,000 0,05764433 0,11925388 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05764433 0,11915143 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05764433 0,11904915 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05764433 0,11894705 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,05764433 0,11884513 ! oligodendrocyte development GO:0014003 10 9 0,000 0,05764433 0,11874338 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,05764433 0,1186418 ! segment specification GO:0007379 13 9 0,000 0,05764433 0,1185404 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05764433 0,11843917 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05764433 0,11833811 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05764433 0,11823722 ! response to amine stimulus GO:0014075 13 9 0,000 0,05764433 0,11813651 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05764433 0,11803597 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05764433 0,1179356 ! erythrocyte development GO:0048821 15 9 0,000 0,05764433 0,1178354 ! gas homeostasis GO:0033483 16 9 0,000 0,05764433 0,11773537 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05764433 0,11763551 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,05764433 0,11753582 ! renal water homeostasis GO:0003091 14 9 0,000 0,05764433 0,11743629 ! postreplication repair GO:0006301 22 9 0,000 0,05764433 0,11733694 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05764433 0,11723775 ! icosanoid secretion GO:0032309 15 9 0,000 0,05764433 0,11713874 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05764433 0,11703988 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05764433 0,1169412 ! regulation of cell division GO:0051302 15 9 0,000 0,05764433 0,11684268 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05764433 0,11674433 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05764433 0,11664614 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05764433 0,11654812 ! sterol catabolic process GO:0016127 11 9 0,000 0,05764433 0,11645026 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05764433 0,11635257 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05764433 0,11625504 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05764433 0,11615767 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05764433 0,11606047 GO:0000084|S phase of mitotic cell cycle, ! musculoskeletal movement GO:0050881 14 9 0,000 0,05764433 0,11596343 GO:0050879|multicellular organismal movement, ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05764433 0,11586655 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05764433 0,11576984 ! purine base metabolic process GO:0006144 21 9 0,000 0,05764433 0,11567328 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05764433 0,11557689 ! pigment granule transport GO:0051904 17 9 0,000 0,05764433 0,11548065 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05764433 0,11538458 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05764433 0,11528866 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05764433 0,11519291 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05764433 0,11509731 ! mitochondrion localization GO:0051646 15 9 0,000 0,05764433 0,11500188 ! kidney development GO:0001822 122 60 1,000 0,05937744 0,11836132 ! mesoderm development GO:0007498 119 61 1,000 0,06113212 0,12175819 ! ear development GO:0043583 103 62 1,000 0,06290442 0,12518449 ! gonad development GO:0008406 98 62 1,000 0,06290442 0,12508103 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,06384157 0,12683965 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,06384157 0,126735 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,06384157 0,12663052 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,06384157 0,12652621 ! synapsis GO:0007129 13 10 0,000 0,06384157 0,12642207 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,06384157 0,1263181 ! N-glycan processing GO:0006491 20 10 0,000 0,06384157 0,12621431 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,06384157 0,12611069 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,06384157 0,12600723 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,06384157 0,12590395 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,06384157 0,12580083 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,06384157 0,12569789 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,06384157 0,12559511 GO:0048200|Golgi transport vesicle coating, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,06384157 0,1254925 ! androgen metabolic process GO:0008209 17 10 0,000 0,06384157 0,12539005 ! phospholipid efflux GO:0033700 16 10 0,000 0,06384157 0,12528778 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,06384157 0,12518567 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,06384157 0,12508373 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06384157 0,12498195 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,06384157 0,12488034 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,06384157 0,12477889 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,06384157 0,12467761 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,06384157 0,12457649 ! endoderm development GO:0007492 16 10 0,000 0,06384157 0,12447554 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,06384157 0,12437475 ! arginine catabolic process GO:0006527 13 10 0,000 0,06384157 0,12427412 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,06384157 0,12417366 ! proline metabolic process GO:0006560 13 10 0,000 0,06384157 0,12407336 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,06384157 0,12397322 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,06384157 0,12387324 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,06384157 0,12377342 ! V(D)J recombination GO:0033151 28 10 0,000 0,06384157 0,12367376 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,06384157 0,12357427 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,06384157 0,12347493 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,06384157 0,12337576 ! B cell proliferation GO:0042100 18 10 0,000 0,06384157 0,12327674 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,06384157 0,12317788 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,06384157 0,12307918 ! multicellular organism growth GO:0035264 18 10 0,000 0,06384157 0,12298064 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,06384157 0,12288225 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,06384157 0,12278403 ! epithelial cell development GO:0002064 20 10 0,000 0,06384157 0,12268595 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,06384157 0,12258804 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,06384157 0,12249028 ! macroautophagy GO:0016236 17 10 0,000 0,06384157 0,12239268 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,06384157 0,12229524 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,06384157 0,12219794 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,06384157 0,12210081 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,06384157 0,12200382 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,06384157 0,121907 ! copper ion homeostasis GO:0055070 13 10 0,000 0,06384157 0,12181032 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,06384157 0,1217138 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,06384157 0,12161743 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,06384157 0,12152121 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,06384157 0,12142515 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,06384157 0,12132924 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,06384157 0,12123348 ! blastoderm segmentation GO:0007350 18 10 0,000 0,06384157 0,12113787 ! response to dsRNA GO:0043331 20 10 0,000 0,06384157 0,12104241 ! DNA ligation GO:0006266 19 10 0,000 0,06384157 0,1209471 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,06384157 0,12085194 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,06384157 0,12075693 ! melanosome localization GO:0032400 16 10 0,000 0,06384157 0,12066207 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,06384157 0,12056736 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,06384157 0,1204728 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,06384157 0,12037838 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,06384157 0,12028412 ! mRNA cleavage GO:0006379 17 10 0,000 0,06384157 0,12019 ! protein sumoylation GO:0016925 15 10 0,000 0,06384157 0,12009602 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,06384157 0,1200022 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06384157 0,11990852 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,06384157 0,11981499 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,06384157 0,1197216 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,06384157 0,11962836 ! salivary gland development GO:0007431 27 10 0,000 0,06384157 0,11953527 ! prophase GO:0051324 15 10 0,000 0,06384157 0,11944231 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,06384157 0,11934951 ! apical protein localization GO:0045176 15 10 0,000 0,06384157 0,11925684 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,06384157 0,11916433 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,06384157 0,11907195 ! midbrain development GO:0030901 13 10 0,000 0,06384157 0,11897972 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,06384157 0,11888763 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,06384157 0,11879568 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,06384157 0,11870388 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,06384157 0,11861221 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,06384157 0,11852069 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,06384157 0,11842931 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,06384157 0,11833807 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,06384157 0,11824697 ! oocyte development GO:0048599 17 10 0,000 0,06384157 0,11815601 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,06384157 0,11806519 ! blastocyst formation GO:0001825 17 10 0,000 0,06384157 0,11797451 ! cerebellar cortex development GO:0021695 15 10 0,000 0,06384157 0,11788397 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,06384157 0,11779357 ! activation of innate immune response GO:0002218 12 10 0,000 0,06384157 0,11770331 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,06384157 0,11761318 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,06384157 0,11752319 ! response to nicotine GO:0035094 20 10 0,000 0,06384157 0,11743335 ! establishment of cell polarity GO:0030010 16 10 0,000 0,06384157 0,11734363 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,06384157 0,11725406 ! detection of external stimulus GO:0009581 91 63 1,000 0,06469403 0,11872909 ! multicellular organism reproduction GO:0032504 111 64 1,000 0,06650064 0,12195163 GO:0048609|reproductive process in a multicellular organism, ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 0,06832396 0,12519989 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,06832396 0,1251046 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of muscle development GO:0048635 20 11 0,000 0,06999826 0,12807285 ! respiratory burst GO:0045730 17 11 0,000 0,06999826 0,12797554 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06999826 0,12787836 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06999826 0,12778134 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06999826 0,12768446 ! thyroid gland development GO:0030878 26 11 0,000 0,06999826 0,12758773 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06999826 0,12749115 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06999826 0,12739471 ! response to pain GO:0048265 24 11 0,000 0,06999826 0,12729842 ! T cell proliferation GO:0042098 26 11 0,000 0,06999826 0,12720227 ! bone resorption GO:0045453 16 11 0,000 0,06999826 0,12710627 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06999826 0,12701041 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06999826 0,1269147 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06999826 0,12681913 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06999826 0,12672371 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06999826 0,12662842 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06999826 0,12653329 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06999826 0,12643829 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,06999826 0,12634344 ! lipid digestion GO:0044241 18 11 0,000 0,06999826 0,12624873 ! UV protection GO:0009650 19 11 0,000 0,06999826 0,12615416 ! adult heart development GO:0007512 14 11 0,000 0,06999826 0,12605973 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,06999826 0,12596545 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06999826 0,1258713 ! temperature homeostasis GO:0001659 17 11 0,000 0,06999826 0,1257773 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06999826 0,12568344 ! negative regulation of ossification GO:0030279 26 11 0,000 0,06999826 0,12558971 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,06999826 0,12549613 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06999826 0,12540268 ! regulation of organ growth GO:0046620 13 11 0,000 0,06999826 0,12530938 ! pigment granule localization GO:0051875 20 11 0,000 0,06999826 0,12521621 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06999826 0,12512318 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06999826 0,12503029 ! embryonic axis specification GO:0000578 18 11 0,000 0,06999826 0,12493754 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06999826 0,12484493 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06999826 0,12475245 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06999826 0,12466011 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06999826 0,1245679 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,06999826 0,12447583 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06999826 0,1243839 ! zymogen activation GO:0031638 15 11 0,000 0,06999826 0,12429211 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06999826 0,12420045 ! neuroblast proliferation GO:0007405 24 11 0,000 0,06999826 0,12410892 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06999826 0,12401753 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06999826 0,12392627 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06999826 0,12383515 ! acid secretion GO:0046717 18 11 0,000 0,06999826 0,12374416 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06999826 0,12365331 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06999826 0,12356259 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06999826 0,123472 ! oocyte differentiation GO:0009994 18 11 0,000 0,06999826 0,12338154 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06999826 0,12329122 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,06999826 0,12320103 ! cholesterol efflux GO:0033344 19 11 0,000 0,06999826 0,12311097 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06999826 0,12302104 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06999826 0,12293124 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,06999826 0,12284158 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,06999826 0,12275204 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06999826 0,12266264 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06999826 0,12257337 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06999826 0,12248422 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06999826 0,12239521 ! defense response to fungus GO:0050832 13 11 0,000 0,06999826 0,12230632 ! lysogeny GO:0030069 21 11 0,000 0,06999826 0,12221756 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06999826 0,12212894 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06999826 0,12204044 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06999826 0,12195207 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06999826 0,12186382 ! regulation of embryonic development GO:0045995 27 11 0,000 0,06999826 0,12177571 ! nucleus localization GO:0051647 19 11 0,000 0,06999826 0,12168772 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06999826 0,12159986 ! actin filament organization GO:0007015 148 66 1,000 0,07016369 0,12179931 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,07201954 0,1249308 ! chromosome segregation GO:0007059 113 67 1,000 0,07201954 0,12484079 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,07201954 0,12475091 ! adaptive immune response GO:0002250 119 67 1,000 0,07201954 0,12466116 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of lipase activity GO:0060191 130 68 1,000 0,07389122 0,12780897 ! urogenital system development GO:0001655 137 69 1,000 0,07577845 0,13097913 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,07611466 0,1314658 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,07611466 0,13137149 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,07611466 0,13127732 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,07611466 0,13118328 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,07611466 0,13108938 ! virus-host interaction GO:0019048 29 12 0,000 0,07611466 0,13099561 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,07611466 0,13090198 ! cartilage condensation GO:0001502 20 12 0,000 0,07611466 0,13080847 ! mating GO:0007618 17 12 0,000 0,07611466 0,13071511 ! protein complex disassembly GO:0043241 27 12 0,000 0,07611466 0,13062187 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,07611466 0,13052877 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,07611466 0,1304358 ! hippocampus development GO:0021766 26 12 0,000 0,07611466 0,13034296 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,07611466 0,13025026 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,07611466 0,13015769 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,07611466 0,13006524 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,07611466 0,12997293 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,07611466 0,12988075 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,07611466 0,12978871 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,07611466 0,12969679 ! drug transport GO:0015893 16 12 0,000 0,07611466 0,129605 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,07611466 0,12951334 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,07611466 0,12942181 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,07611466 0,12933041 ! polyamine metabolic process GO:0006595 17 12 0,000 0,07611466 0,12923914 ! mitotic spindle organization GO:0007052 21 12 0,000 0,07611466 0,129148 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,07611466 0,12905699 ! asymmetric protein localization GO:0008105 20 12 0,000 0,07611466 0,1289661 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,07611466 0,12887534 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,07611466 0,12878471 ! entry into host cell GO:0030260 32 12 0,000 0,07611466 0,12869421 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,07611466 0,12860384 ! monoamine transport GO:0015844 18 12 0,000 0,07611466 0,12851359 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07611466 0,12842347 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,07611466 0,12833347 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,07611466 0,1282436 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,07611466 0,12815386 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07611466 0,12806424 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,07611466 0,12797475 ! protein homotetramerization GO:0051289 21 12 0,000 0,07611466 0,12788538 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,07611466 0,12779614 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,07611466 0,12770702 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,07611466 0,12761802 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,07611466 0,12752915 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,07611466 0,12744041 ! fucose catabolic process GO:0019317 22 12 0,000 0,07611466 0,12735178 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,07611466 0,12726328 ! histone methylation GO:0016571 26 12 0,000 0,07611466 0,1271749 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,07611466 0,12708665 ! autonomic nervous system development GO:0048483 24 12 0,000 0,07611466 0,12699852 ! gland morphogenesis GO:0022612 29 12 0,000 0,07611466 0,12691051 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,07611466 0,12682262 ! T cell homeostasis GO:0043029 25 12 0,000 0,07611466 0,12673485 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,07611466 0,12664721 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,07611466 0,12655968 ! spleen development GO:0048536 22 12 0,000 0,07611466 0,12647228 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,07611466 0,126385 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,07611466 0,12629784 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,07611466 0,12621079 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,07611466 0,12612387 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,07611466 0,12603707 ! response to cold GO:0009409 17 12 0,000 0,07611466 0,12595039 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,07611466 0,12586382 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,07611466 0,12577738 ! reproductive structure development GO:0048608 113 71 1,000 0,07959841 0,13144391 ! humoral immune response GO:0006959 109 71 1,000 0,07959841 0,13135375 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,07959841 0,13126372 ! regulation of immune effector process GO:0002697 137 71 1,000 0,07959841 0,13117382 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,08153058 0,13426597 ! cGMP metabolic process GO:0046068 18 13 0,000 0,08219103 0,13526103 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,08219103 0,13516857 ! regulation of chemokine production GO:0032642 18 13 0,000 0,08219103 0,13507625 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,08219103 0,13498404 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,08219103 0,13489197 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,08219103 0,13480002 ! lipid localization GO:0010876 28 13 0,000 0,08219103 0,13470819 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,08219103 0,13461649 ! organelle fusion GO:0048284 32 13 0,000 0,08219103 0,13452491 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,08219103 0,13443346 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,08219103 0,13434214 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,08219103 0,13425093 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,08219103 0,13415985 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,08219103 0,1340689 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,08219103 0,13397806 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,08219103 0,13388736 ! methionine metabolic process GO:0006555 27 13 0,000 0,08219103 0,13379677 ! plasma membrane organization GO:0007009 24 13 0,000 0,08219103 0,1337063 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,08219103 0,13361596 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,08219103 0,13352574 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,08219103 0,13343564 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,08219103 0,13334567 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,08219103 0,13325581 ! response to X-ray GO:0010165 25 13 0,000 0,08219103 0,13316608 ! cytokine metabolic process GO:0042107 22 13 0,000 0,08219103 0,13307646 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,08219103 0,13298697 ! exocrine system development GO:0035272 32 13 0,000 0,08219103 0,1328976 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,08219103 0,13280834 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,08219103 0,13271921 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,08219103 0,1326302 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,08219103 0,1325413 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,08219103 0,13245253 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,08219103 0,13236387 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,08219103 0,13227533 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,08219103 0,13218691 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,08219103 0,13209861 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,08219103 0,13201043 ! regulation of cellular pH GO:0030641 22 13 0,000 0,08219103 0,13192236 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,08219103 0,13183442 ! ribosome assembly GO:0042255 17 13 0,000 0,08219103 0,13174658 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,08219103 0,13165887 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,08219103 0,13157127 ! chromatin silencing GO:0006342 26 13 0,000 0,08219103 0,13148379 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,08219103 0,13139643 ! regulation of epidermis development GO:0045682 19 13 0,000 0,08219103 0,13130918 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,08219103 0,13122205 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,08219103 0,13113503 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,08219103 0,13104813 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,08219103 0,13096134 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,08219103 0,13087467 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,08219103 0,13078811 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,08219103 0,13070167 ! embryonic placenta development GO:0001892 23 13 0,000 0,08219103 0,13061534 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,08219103 0,13052912 ! insulin secretion GO:0030073 23 13 0,000 0,08219103 0,13044302 ! actin filament polymerization GO:0030041 24 13 0,000 0,08219103 0,13035704 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,08219103 0,13027116 ! acrosome reaction GO:0007340 18 13 0,000 0,08219103 0,1301854 ! learning or memory GO:0007611 147 73 1,000 0,08347719 0,13213561 ! regulation of blood pressure GO:0008217 125 73 1,000 0,08347719 0,13204873 ! transition metal ion transport GO:0000041 126 74 1,000 0,08543796 0,13506158 ! meiosis GO:0007126 121 74 1,000 0,08543796 0,1349729 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 163 75 1,000 0,08741262 0,13800182 ! meiotic cell cycle GO:0051321 122 75 1,000 0,08741262 0,13791132 ! rhythmic process GO:0048511 128 75 1,000 0,08741262 0,13782095 ! rRNA transcription GO:0009303 25 14 0,000 0,08822764 0,13901487 ! lactation GO:0007595 26 14 0,000 0,08822764 0,1389239 ! reproductive cellular process GO:0048610 20 14 0,000 0,08822764 0,13883304 ! tRNA modification GO:0006400 20 14 0,000 0,08822764 0,1387423 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,08822764 0,13865167 ! regulation of S phase GO:0033261 23 14 0,000 0,08822764 0,13856117 ! water transport GO:0006833 21 14 0,000 0,08822764 0,13847078 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,08822764 0,13838052 ! non-recombinational repair GO:0000726 25 14 0,000 0,08822764 0,13829037 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,08822764 0,13820033 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,08822764 0,13811042 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,08822764 0,13802062 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,08822764 0,13793094 ! RNA polyadenylation GO:0043631 30 14 0,000 0,08822764 0,13784137 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,08822764 0,13775192 ! palate development GO:0060021 31 14 0,000 0,08822764 0,13766259 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,08822764 0,13757337 ! regulated secretory pathway GO:0045055 23 14 0,000 0,08822764 0,13748427 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,08822764 0,13739528 ! arginine metabolic process GO:0006525 17 14 0,000 0,08822764 0,13730641 ! regulation of heart rate GO:0002027 24 14 0,000 0,08822764 0,13721766 ! organic alcohol transport GO:0015850 29 14 0,000 0,08822764 0,13712901 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,08822764 0,13704049 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,08822764 0,13695207 ! embryo implantation GO:0007566 30 14 0,000 0,08822764 0,13686377 ! neutral amino acid transport GO:0015804 26 14 0,000 0,08822764 0,13677559 ! L-amino acid transport GO:0015807 30 14 0,000 0,08822764 0,13668752 ! stem cell development GO:0048864 43 14 0,000 0,08822764 0,13659956 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,08822764 0,13651171 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,08822764 0,13642398 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,08822764 0,13633636 ! cerebellum development GO:0021549 21 14 0,000 0,08822764 0,13624885 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,08822764 0,13616146 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,08822764 0,13607417 ! response to gamma radiation GO:0010332 28 14 0,000 0,08822764 0,135987 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,08822764 0,13589994 ! cofactor transport GO:0051181 26 14 0,000 0,08822764 0,135813 ! NADP metabolic process GO:0006739 24 14 0,000 0,08822764 0,13572616 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,08822764 0,13563943 ! intestinal absorption GO:0050892 25 14 0,000 0,08822764 0,13555282 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,08822764 0,13546631 ! oxygen transport GO:0015671 21 14 0,000 0,08822764 0,13537992 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08822764 0,13529363 ! male genitalia development GO:0030539 24 14 0,000 0,08822764 0,13520746 ! regulation of axon extension GO:0030516 37 14 0,000 0,08822764 0,1351214 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,08822764 0,13503544 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,08940091 0,13674418 ! defense response to bacterium GO:0042742 89 76 1,000 0,08940091 0,1366573 ! neuropeptide signaling pathway GO:0007218 107 77 1,000 0,09140256 0,1396283 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,09140256 0,1395397 ! blood coagulation GO:0007596 146 78 1,000 0,09341732 0,1425251 GO:0050817|coagulation, ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,09422475 0,14366588 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,09422475 0,14357489 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,09422475 0,14348402 ! superoxide anion generation GO:0042554 20 15 0,000 0,09422475 0,14339327 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,09422475 0,14330263 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,09422475 0,1432121 ! copper ion transport GO:0006825 20 15 0,000 0,09422475 0,14312169 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,09422475 0,14303139 ! sulfate transport GO:0008272 23 15 0,000 0,09422475 0,14294121 ! response to cAMP GO:0051591 22 15 0,000 0,09422475 0,14285114 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,09422475 0,14276118 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,09422475 0,14267134 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,09422475 0,14258161 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,09422475 0,14249199 ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,09422475 0,14240248 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,09422475 0,14231309 ! vesicle coating GO:0006901 33 15 0,000 0,09422475 0,14222381 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,09422475 0,14213464 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,09422475 0,14204558 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,09422475 0,14195664 ! regulation of exocytosis GO:0017157 22 15 0,000 0,09422475 0,14186781 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,09422475 0,14177908 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,09422475 0,14169047 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,09422475 0,14160197 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,09422475 0,14151358 ! regulation of vasodilation GO:0042312 26 15 0,000 0,09422475 0,1414253 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,09422475 0,14133713 ! histone deacetylation GO:0016575 20 15 0,000 0,09422475 0,14124907 ! tissue regeneration GO:0042246 26 15 0,000 0,09422475 0,14116112 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,09422475 0,14107328 ! water homeostasis GO:0030104 27 15 0,000 0,09422475 0,14098554 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,09422475 0,14089792 ! muscle maintenance GO:0046716 26 15 0,000 0,09422475 0,14081041 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,09422475 0,140723 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,09422475 0,1406357 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,09422475 0,14054851 ! dopamine metabolic process GO:0042417 35 15 0,000 0,09422475 0,14046143 ! heme biosynthetic process GO:0006783 29 15 0,000 0,09422475 0,14037446 ! cell killing GO:0001906 29 15 0,000 0,09422475 0,14028759 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,09422475 0,14020084 ! detection of bacterium GO:0016045 18 15 0,000 0,09422475 0,14011419 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,09422475 0,14002764 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,09422475 0,13994121 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,09422475 0,13985488 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,09422475 0,13976865 ! peptide hormone processing GO:0016486 23 15 0,000 0,09422475 0,13968253 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,09544493 0,14140425 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,09544493 0,14131723 ! muscle cell differentiation GO:0042692 159 80 1,000 0,09748513 0,14424922 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,09953768 0,14719586 GO:0045937|positive regulation of phosphate metabolic process, ! cell-substrate adhesion GO:0031589 171 81 1,000 0,09953768 0,14710544 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,09953768 0,14701514 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,10018261 0,14787691 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,10018261 0,14778624 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,10018261 0,14769569 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,10018261 0,14760524 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,10018261 0,14751491 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,10018261 0,14742469 ! bone remodeling GO:0046849 27 16 0,000 0,10018261 0,14733457 ! filopodium assembly GO:0046847 32 16 0,000 0,10018261 0,14724457 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,10018261 0,14715468 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,10018261 0,1470649 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,10018261 0,14697522 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,10018261 0,14688566 ! startle response GO:0001964 28 16 0,000 0,10018261 0,1467962 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,10018261 0,14670686 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,10018261 0,14661762 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,10018261 0,14652849 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,10018261 0,14643947 ! protein polyubiquitination GO:0000209 34 16 0,000 0,10018261 0,14635056 ! glutamate metabolic process GO:0006536 22 16 0,000 0,10018261 0,14626175 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,10018261 0,14617305 ! response to osmotic stress GO:0006970 25 16 0,000 0,10018261 0,14608446 ! lysosomal transport GO:0007041 26 16 0,000 0,10018261 0,14599598 ! fructose metabolic process GO:0006000 25 16 0,000 0,10018261 0,14590761 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,10018261 0,14581934 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,10018261 0,14573118 ! intermediate filament-based process GO:0045103 32 16 0,000 0,10018261 0,14564312 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,10018261 0,14555517 ! negative regulation of immune response GO:0050777 35 16 0,000 0,10018261 0,14546733 ! axon cargo transport GO:0008088 43 16 0,000 0,10018261 0,14537959 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,10018261 0,14529196 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,10018261 0,14520444 ! DNA replication initiation GO:0006270 27 16 0,000 0,10018261 0,14511702 ! neuron recognition GO:0008038 35 16 0,000 0,10018261 0,1450297 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,10018261 0,14494249 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,10018261 0,14485539 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,10018261 0,14476839 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,10018261 0,14468149 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,10018261 0,1445947 GO:0046466|membrane lipid catabolic process, ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,10018261 0,14450801 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,10018261 0,14442143 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,10018261 0,14433495 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,10018261 0,14424857 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,10018261 0,1441623 ! defense response to virus GO:0051607 37 16 0,000 0,10018261 0,14407613 ! hemostasis GO:0007599 158 84 1,000 0,10576691 0,15201625 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,10576691 0,15192549 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,10610148 0,15231513 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,10610148 0,15222431 ! metencephalon development GO:0022037 30 17 0,000 0,10610148 0,15213359 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,10610148 0,15204298 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,10610148 0,15195248 ! signal complex assembly GO:0007172 41 17 0,000 0,10610148 0,15186208 ! inositol metabolic process GO:0006020 28 17 0,000 0,10610148 0,1517718 ! gene silencing by RNA GO:0031047 36 17 0,000 0,10610148 0,15168162 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,10610148 0,15159154 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,10610148 0,15150158 ! adult walking behavior GO:0007628 33 17 0,000 0,10610148 0,15141172 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,10610148 0,15132197 ! heart looping GO:0001947 30 17 0,000 0,10610148 0,15123232 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,10610148 0,15114278 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,10610148 0,15105335 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,10610148 0,15096402 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,10610148 0,1508748 ! glycine metabolic process GO:0006544 28 17 0,000 0,10610148 0,15078568 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,10610148 0,15069667 ! NAD metabolic process GO:0019674 29 17 0,000 0,10610148 0,15060776 ! membrane budding GO:0006900 37 17 0,000 0,10610148 0,15051896 ! DNA integration GO:0015074 29 17 0,000 0,10610148 0,15043027 ! regulation of protein binding GO:0043393 33 17 0,000 0,10610148 0,15034167 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,10610148 0,15025318 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,10610148 0,1501648 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,10610148 0,15007652 ! genitalia development GO:0048806 30 17 0,000 0,10610148 0,14998834 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,10610148 0,14990027 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,10610148 0,1498123 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,10610148 0,14972443 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,10610148 0,14963667 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,10610148 0,14954901 ! steroid catabolic process GO:0006706 31 17 0,000 0,10610148 0,14946145 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,10610148 0,149374 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,10610148 0,14928664 ! gas transport GO:0015669 25 17 0,000 0,10610148 0,14919939 ! organic cation transport GO:0015695 31 17 0,000 0,10610148 0,14911224 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,10610148 0,1490252 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,10610148 0,14893825 ! microspike assembly GO:0030035 36 17 0,000 0,10610148 0,14885141 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,10610148 0,14876466 ! nucleosome assembly GO:0006334 122 85 1,000 0,10786638 0,15115114 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,10786638 0,15106316 GO:0002696|positive regulation of leukocyte activation, ! chromatin assembly GO:0031497 124 86 1,000 0,10997697 0,15392938 ! tube morphogenesis GO:0035239 176 86 1,000 0,10997697 0,15383988 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,11198161 0,15655302 ! neuron maturation GO:0042551 42 18 0,000 0,11198161 0,15646211 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,11198161 0,1563713 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,11198161 0,1562806 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,11198161 0,15619 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,11198161 0,15609951 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,11198161 0,15600912 ! memory GO:0007613 31 18 0,000 0,11198161 0,15591884 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,11198161 0,15582866 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,11198161 0,15573859 ! patterning of blood vessels GO:0001569 39 18 0,000 0,11198161 0,15564862 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,11198161 0,15555875 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,11198161 0,15546899 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,11198161 0,15537933 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,11198161 0,15528977 ! glutamine metabolic process GO:0006541 29 18 0,000 0,11198161 0,15520032 ! response to retinoic acid GO:0032526 26 18 0,000 0,11198161 0,15511097 ! response to fungus GO:0009620 21 18 0,000 0,11198161 0,15502172 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,11198161 0,15493258 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,11198161 0,15484354 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,11198161 0,1547546 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,11198161 0,15466576 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,11198161 0,15457702 ! vitamin transport GO:0051180 27 18 0,000 0,11198161 0,15448839 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,11198161 0,15439986 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,11198161 0,15431143 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,11198161 0,1542231 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,11198161 0,15413487 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,11198161 0,15404674 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,11198161 0,15395872 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,11198161 0,15387079 ! regulation of neurological system process GO:0031644 148 88 1,000 0,11423061 0,15687149 ! protein secretion GO:0009306 39 19 0,000 0,11782325 0,16171292 ! positive regulation of translation GO:0045727 30 19 0,000 0,11782325 0,16162072 ! negative regulation of defense response GO:0031348 25 19 0,000 0,11782325 0,16152863 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,11782325 0,16143664 ! skin development GO:0043588 36 19 0,000 0,11782325 0,16134476 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,11782325 0,16125299 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,11782325 0,16116131 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,11782325 0,16106974 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,11782325 0,16097828 ! bile acid metabolic process GO:0008206 29 19 0,000 0,11782325 0,16088692 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,11782325 0,16079566 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,11782325 0,16070451 ! pigmentation during development GO:0048066 41 19 0,000 0,11782325 0,16061345 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,11782325 0,16052251 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,11782325 0,16043166 ! heme metabolic process GO:0042168 36 19 0,000 0,11782325 0,16034092 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,11782325 0,16025028 ! plasma membrane fusion GO:0045026 28 19 0,000 0,11782325 0,16015974 ! peptide cross-linking GO:0018149 37 19 0,000 0,11782325 0,16006931 ! protein export from nucleus GO:0006611 36 19 0,000 0,11782325 0,15997898 ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,11782325 0,15988875 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,11782325 0,15979862 ! visual learning GO:0008542 36 19 0,000 0,11782325 0,15970859 ! cellular pigmentation GO:0033059 36 19 0,000 0,11782325 0,15961866 ! G1 phase GO:0051318 40 19 0,000 0,11782325 0,15952884 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,11782325 0,15943912 ! cell-cell junction organization GO:0045216 35 19 0,000 0,11782325 0,15934949 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,11782325 0,15925997 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,11782325 0,15917055 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,11782325 0,15908123 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,11782325 0,15899201 ! cilium assembly GO:0042384 37 19 0,000 0,11782325 0,15890289 ! peptide hormone secretion GO:0030072 31 19 0,000 0,11782325 0,15881386 ! sex differentiation GO:0007548 145 90 1,000 0,11852597 0,15967161 ! protein-DNA complex assembly GO:0065004 130 90 1,000 0,11852597 0,15958225 ! regulation of defense response GO:0031347 149 92 1,000 0,12286125 0,16532672 ! nucleosome organization GO:0034728 138 92 1,000 0,12286125 0,1652343 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,12362666 0,16617081 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,12362666 0,16607803 ! positive regulation of ossification GO:0045778 47 20 0,000 0,12362666 0,16598535 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,12362666 0,16589278 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,12362666 0,16580031 ! cAMP metabolic process GO:0046058 36 20 0,000 0,12362666 0,16570794 ! response to vitamin GO:0033273 31 20 0,000 0,12362666 0,16561567 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,12362666 0,16552351 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,12362666 0,16543145 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,12362666 0,16533949 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,12362666 0,16524764 ! retinoid metabolic process GO:0001523 32 20 0,000 0,12362666 0,16515589 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,12362666 0,16506423 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,12362666 0,16497268 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,12362666 0,16488124 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,12362666 0,16478989 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,12362666 0,16469864 ! body fluid secretion GO:0007589 31 20 0,000 0,12362666 0,1646075 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,12362666 0,16451645 ! peptide secretion GO:0002790 35 20 0,000 0,12362666 0,16442551 ! stem cell differentiation GO:0048863 53 20 0,000 0,12362666 0,16433467 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,12362666 0,16424393 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,12362666 0,16415328 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,12362666 0,16406274 ! sensory perception of pain GO:0019233 30 20 0,000 0,12362666 0,1639723 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,12362666 0,16388196 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,12362666 0,16379171 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,12362666 0,16370157 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,12362666 0,16361152 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,12362666 0,16352158 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,12362666 0,16343173 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,12362666 0,16334198 ! regulation of glucose import GO:0046324 29 20 0,000 0,12362666 0,16325233 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,12362666 0,16316278 ! actin filament-based movement GO:0030048 43 20 0,000 0,12362666 0,16307333 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,12362666 0,16298397 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,12362666 0,16289471 ! negative regulation of translation GO:0017148 29 20 0,000 0,12362666 0,16280556 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,12362666 0,16271649 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,12362666 0,16262753 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,1250433 0,1644012 ! regulation of cell killing GO:0031341 42 21 0,000 0,12939208 0,17002586 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,12939208 0,16993305 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,12939208 0,16984035 ! hormone secretion GO:0046879 38 21 0,000 0,12939208 0,16974774 ! glycerol metabolic process GO:0006071 34 21 0,000 0,12939208 0,16965523 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,12939208 0,16956283 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,12939208 0,16947053 ! axis specification GO:0009798 38 21 0,000 0,12939208 0,16937832 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,12939208 0,16928622 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,12939208 0,16919422 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,12939208 0,16910231 ! cell aging GO:0007569 44 21 0,000 0,12939208 0,16901051 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,12939208 0,1689188 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,12939208 0,1688272 ! cytolysis GO:0019835 24 21 0,000 0,12939208 0,16873569 ! vasodilation GO:0042311 39 21 0,000 0,12939208 0,16864429 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,12939208 0,16855298 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,12939208 0,16846177 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,12939208 0,16837066 ! oogenesis GO:0048477 36 21 0,000 0,12939208 0,16827965 ! DNA modification GO:0006304 34 21 0,000 0,12939208 0,16818874 ! collagen fibril organization GO:0030199 59 21 0,000 0,12939208 0,16809792 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,12939208 0,16800721 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,12939208 0,16791659 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,12939208 0,16782607 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,12939208 0,16773564 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,12939208 0,16764532 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,12939208 0,16755509 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,12939208 0,16746496 ! collagen catabolic process GO:0030574 28 21 0,000 0,12939208 0,16737492 ! sperm-egg recognition GO:0035036 21 21 0,000 0,12939208 0,16728498 ! detection of stimulus GO:0051606 151 96 1,000 0,13164452 0,17010564 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,13386256 0,17287887 ! protein ubiquitination GO:0016567 217 97 1,000 0,13386256 0,17278612 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,13511977 0,17431537 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,13511977 0,17422195 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,13511977 0,17412864 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,13511977 0,17403542 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,13511977 0,1739423 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,13511977 0,17384928 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,13511977 0,17375637 ! regeneration GO:0031099 41 22 0,000 0,13511977 0,17366355 ! keratinization GO:0031424 28 22 0,000 0,13511977 0,17357083 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,13511977 0,17347821 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,13511977 0,17338569 ! sensory perception of taste GO:0050909 28 22 0,000 0,13511977 0,17329326 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,13511977 0,17320094 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,13511977 0,17310871 ! vacuolar transport GO:0007034 36 22 0,000 0,13511977 0,17301658 ! lysosome organization GO:0007040 41 22 0,000 0,13511977 0,17292455 ! central nervous system neuron development GO:0021954 46 22 0,000 0,13511977 0,17283262 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,13511977 0,17274079 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,13511977 0,17264905 ! fucose metabolic process GO:0006004 39 22 0,000 0,13511977 0,17255741 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,13511977 0,17246587 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,13511977 0,17237442 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,13511977 0,17228308 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,13511977 0,17219182 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,13511977 0,17210067 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,13511977 0,17200961 ! sarcomere organization GO:0045214 30 22 0,000 0,13511977 0,17191865 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,13511977 0,17182778 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,13511977 0,17173701 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,13511977 0,17164634 ! protein stabilization GO:0050821 39 22 0,000 0,13511977 0,17155576 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,14080996 0,17868606 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,14080996 0,17859186 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,14080996 0,17849777 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,14080996 0,17840377 ! gluconeogenesis GO:0006094 33 23 0,000 0,14080996 0,17830987 ! viral genome replication GO:0019079 41 23 0,000 0,14080996 0,17821608 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,14080996 0,17812238 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,14080996 0,17802878 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,14080996 0,17793527 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,14080996 0,17784187 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,14080996 0,17774856 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,14080996 0,17765535 ! visual behavior GO:0007632 42 23 0,000 0,14080996 0,17756224 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,14080996 0,17746923 ! response to ethanol GO:0045471 46 23 0,000 0,14080996 0,17737631 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,14080996 0,1772835 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,14080996 0,17719077 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,14080996 0,17709815 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,14080996 0,17700562 GO:0042278|purine nucleoside metabolic process, ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,14080996 0,17691319 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,14080996 0,17682086 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,14080996 0,17672862 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,14080996 0,17663648 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,14080996 0,17654443 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,14080996 0,17645248 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,14080996 0,17636063 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,14080996 0,17626887 ! fatty acid transport GO:0015908 44 23 0,000 0,14080996 0,1761772 ! platelet activation GO:0030168 37 23 0,000 0,14080996 0,17608563 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,14080996 0,17599416 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,14080996 0,17590278 ! hormone transport GO:0009914 40 23 0,000 0,14080996 0,1758115 ! cell-cell recognition GO:0009988 25 23 0,000 0,14080996 0,17572031 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,14080996 0,17562922 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,14080996 0,17553822 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,14080996 0,17544731 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,14080996 0,1753565 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,1464629 0,18230199 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,1464629 0,18220772 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,1464629 0,18211356 ! vesicle docking GO:0048278 47 24 0,000 0,1464629 0,18201949 ! vacuole organization GO:0007033 43 24 0,000 0,1464629 0,18192552 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,1464629 0,18183165 ! digestive system process GO:0022600 39 24 0,000 0,1464629 0,18173787 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,1464629 0,1816442 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,1464629 0,18155061 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,1464629 0,18145713 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,1464629 0,18136374 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,1464629 0,18127044 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,1464629 0,18117724 ! membrane depolarization GO:0051899 39 24 0,000 0,1464629 0,18108414 ! pentose metabolic process GO:0019321 35 24 0,000 0,1464629 0,18099113 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,1464629 0,18089822 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,1464629 0,18080541 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,1464629 0,18071269 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,1464629 0,18062006 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,1464629 0,18052753 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,1464629 0,18043509 ! regulation of amine transport GO:0051952 40 24 0,000 0,1464629 0,18034275 ! protein tetramerization GO:0051262 52 24 0,000 0,1464629 0,18025051 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,15207884 0,1870663 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,15207884 0,18697071 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,15207884 0,18687522 ! phototransduction GO:0007602 33 25 0,000 0,15207884 0,18677983 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,15207884 0,18668453 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,15207884 0,18658933 ! sperm motility GO:0030317 31 25 0,000 0,15207884 0,18649423 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,15207884 0,18639923 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,15207884 0,18630432 ! receptor metabolic process GO:0043112 46 25 0,000 0,15207884 0,18620951 ! chromosome condensation GO:0030261 45 25 0,000 0,15207884 0,18611479 ! response to starvation GO:0042594 42 25 0,000 0,15207884 0,18602017 ! osteoblast differentiation GO:0001649 60 25 0,000 0,15207884 0,18592565 ! neural crest cell development GO:0014032 54 25 0,000 0,15207884 0,18583122 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,15207884 0,18573689 ! negative regulation of cell development GO:0010721 73 25 0,000 0,15207884 0,18564266 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,15207884 0,18554852 ! interaction with host GO:0051701 62 25 0,000 0,15207884 0,18545448 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,15207884 0,18536053 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,15207884 0,18526667 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,15207884 0,18517291 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,15207884 0,18507925 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,15207884 0,18498568 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,15207884 0,18489221 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,15207884 0,18479883 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,15207884 0,18470554 ! telomere organization GO:0032200 43 25 0,000 0,15207884 0,18461235 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,15207884 0,18451925 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,15207884 0,18442625 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,15765801 0,1910958 ! embryonic pattern specification GO:0009880 44 26 0,000 0,15765801 0,19099958 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,15765801 0,19090345 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,15765801 0,19080743 ! initiation of viral infection GO:0019059 57 26 0,000 0,15765801 0,19071149 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,15765801 0,19061566 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,15765801 0,19051992 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,15765801 0,19042428 ! molting cycle process GO:0022404 50 26 0,000 0,15765801 0,19032873 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,15765801 0,19023328 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,15765801 0,19013793 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,15765801 0,19004267 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,15765801 0,1899475 GO:0051297|centrosome organization, ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,15765801 0,18985243 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,15765801 0,18975746 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,15765801 0,18966258 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,15765801 0,1895678 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,15765801 0,18947311 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,15765801 0,18937851 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,15765801 0,18928401 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,15765801 0,18918961 ! blastocyst development GO:0001824 49 26 0,000 0,15765801 0,1890953 ! leukocyte proliferation GO:0070661 52 26 0,000 0,15765801 0,18900108 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,15765801 0,18890695 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,15765801 0,18881292 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,16320065 0,19535361 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,16320065 0,19525647 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,16320065 0,19515943 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,16320065 0,19506248 ! fat cell differentiation GO:0045444 50 27 0,000 0,16320065 0,19496562 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,16320065 0,19486887 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,16320065 0,19477221 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,16320065 0,19467564 ! autophagy GO:0006914 41 27 0,000 0,16320065 0,19457917 ! male gonad development GO:0008584 44 27 0,000 0,16320065 0,1944828 ! response to toxin GO:0009636 47 27 0,000 0,16320065 0,19438652 ! primary neural tube formation GO:0014020 51 27 0,000 0,16320065 0,19429033 ! base-excision repair GO:0006284 41 27 0,000 0,16320065 0,19419425 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,16320065 0,19409825 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,16320065 0,19400235 ! glutathione metabolic process GO:0006749 39 27 0,000 0,16320065 0,19390655 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,16320065 0,19381084 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,16320065 0,19371523 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,16320065 0,19361971 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,16870701 0,20005375 ! circadian rhythm GO:0007623 50 28 0,000 0,16870701 0,1999552 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,16870701 0,19985675 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,16870701 0,1997584 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,16870701 0,19966014 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,16870701 0,19956198 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,16870701 0,19946391 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,16870701 0,19936594 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,16870701 0,19926807 ! synaptogenesis GO:0007416 42 28 0,000 0,16870701 0,19917029 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,16870701 0,19907261 ! lipid oxidation GO:0034440 43 28 0,000 0,16870701 0,19897503 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,16870701 0,19887754 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,16870701 0,19878015 ! translational initiation GO:0006413 65 29 0,000 0,17417731 0,20512512 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,17417731 0,20502476 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,17417731 0,20492451 ! regulation of pH GO:0006885 43 29 0,000 0,17417731 0,20482435 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,17417731 0,20472429 ! catechol metabolic process GO:0009712 54 29 0,000 0,17417731 0,20462432 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,17417731 0,20452446 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,17417731 0,20442469 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,17417731 0,20432502 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,17417731 0,20422545 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,17417731 0,20412597 ! cell fate determination GO:0001709 60 29 0,000 0,17417731 0,20402659 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,17417731 0,20392731 ! detection of light stimulus GO:0009583 38 29 0,000 0,17417731 0,20382812 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,17417731 0,20372903 ! regulation of coagulation GO:0050818 46 29 0,000 0,17417731 0,20363004 ! phenol metabolic process GO:0018958 55 30 0,000 0,1796118 0,20988149 ! zinc ion transport GO:0006829 45 30 0,000 0,1796118 0,20977961 ! membrane docking GO:0022406 61 30 0,000 0,1796118 0,20967782 ! regulation of innate immune response GO:0045088 51 30 0,000 0,1796118 0,20957614 ! acute-phase response GO:0006953 49 30 0,000 0,1796118 0,20947455 ! myofibril assembly GO:0030239 47 30 0,000 0,1796118 0,20937306 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,1796118 0,20927167 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,1796118 0,20917037 ! phospholipid transport GO:0015914 51 30 0,000 0,1796118 0,20906918 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,1796118 0,20896808 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,1796118 0,20886708 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,1796118 0,20876618 ! response to heat GO:0009408 50 30 0,000 0,1796118 0,20866538 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,18501071 0,21483386 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,18501071 0,21473023 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,18501071 0,21462669 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,18501071 0,21452326 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,18501071 0,21441992 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,18501071 0,21431669 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,18501071 0,21421355 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,18501071 0,21411051 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,18501071 0,21400758 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,18501071 0,21390474 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,18501071 0,213802 ! peptide transport GO:0015833 55 31 0,000 0,18501071 0,21369936 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,18501071 0,21359681 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,18501071 0,21349437 ! natural killer cell activation GO:0030101 45 31 0,000 0,18501071 0,21339202 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,18501071 0,21328977 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,18501071 0,21318762 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,18501071 0,21308557 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,18501071 0,21298362 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,19037426 0,21905331 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,19037426 0,2189486 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,19037426 0,21884399 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,19037426 0,21873948 ! cholesterol transport GO:0030301 56 32 0,000 0,19037426 0,21863507 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,19037426 0,21853076 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,19037426 0,21842655 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,19037426 0,21832244 ! response to ionizing radiation GO:0010212 65 32 0,000 0,19037426 0,21821842 ! muscle cell development GO:0055001 49 32 0,000 0,19037426 0,21811451 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,19037426 0,2180107 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,19037426 0,21790698 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,19037426 0,21780336 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,19037426 0,21769984 ! BMP signaling pathway GO:0030509 64 32 0,000 0,19037426 0,21759642 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,19037426 0,2174931 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,19037426 0,21738988 ! gene silencing GO:0016458 65 32 0,000 0,19037426 0,21728675 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,19570269 0,22326253 ! post-embryonic development GO:0009791 69 33 0,000 0,19570269 0,22315672 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,19570269 0,22305101 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,19570269 0,2229454 ! ceramide metabolic process GO:0006672 64 33 0,000 0,19570269 0,22283989 ! sterol transport GO:0015918 57 33 0,000 0,19570269 0,22273447 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,19570269 0,22262916 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,19570269 0,22252395 ! adult locomotory behavior GO:0008344 59 33 0,000 0,19570269 0,22241884 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,20099623 0,22832717 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,20099623 0,22821941 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,20099623 0,22811176 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,20099623 0,22800421 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,20099623 0,22789677 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,20099623 0,22778942 ! mismatch repair GO:0006298 46 34 0,000 0,20099623 0,22768217 ! spermatid development GO:0007286 63 34 0,000 0,20099623 0,22757503 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,20099623 0,22746799 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,20099623 0,22736104 ! placenta development GO:0001890 53 34 0,000 0,20099623 0,2272542 ! regulation of muscle development GO:0048634 70 35 0,000 0,20625511 0,23309055 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,20625511 0,23298112 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,20625511 0,23287179 GO:0006639|acylglycerol metabolic process, ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,20625511 0,23276257 ! cytokine production GO:0001816 59 35 0,000 0,20625511 0,23265344 ! neural tube formation GO:0001841 67 35 0,000 0,20625511 0,23254442 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,21147954 0,23832308 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,21147954 0,23821151 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,21147954 0,23810004 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,21147954 0,23798867 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,21147954 0,23787741 ! positive regulation of cell development GO:0010720 80 36 0,000 0,21147954 0,23776625 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,21147954 0,2376552 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,21147954 0,23754425 ! aerobic respiration GO:0009060 55 36 0,000 0,21147954 0,2374334 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,21147954 0,23732266 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,21147954 0,23721202 ! RNA export from nucleus GO:0006405 56 37 0,000 0,21666977 0,24292053 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,21666977 0,24280739 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,21666977 0,24269435 ! actomyosin structure organization GO:0031032 62 37 0,000 0,21666977 0,24258141 ! organic anion transport GO:0015711 68 37 0,000 0,21666977 0,24246858 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,21666977 0,24235586 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,21666977 0,24224324 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,21666977 0,24213073 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,21666977 0,24201832 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,21666977 0,24190601 ! spermatid differentiation GO:0048515 66 37 0,000 0,21666977 0,24179381 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,221826 0,24743317 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,221826 0,24731851 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,221826 0,24720396 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,221826 0,24708951 ! lipid homeostasis GO:0055088 67 38 0,000 0,221826 0,24697517 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,221826 0,24686094 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,221826 0,24674681 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,221826 0,24663278 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,221826 0,24651887 ! mRNA catabolic process GO:0006402 71 39 0,000 0,22694846 0,2520951 ! organic ether metabolic process GO:0018904 55 39 0,000 0,22694846 0,25197876 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,22694846 0,25186254 ! ion transmembrane transport GO:0034220 66 39 0,000 0,22694846 0,25174642 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,22694846 0,25163041 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,22694846 0,2515145 ! RNA modification GO:0009451 57 39 0,000 0,22694846 0,2513987 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,22694846 0,25128301 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,23203736 0,2567994 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,23203736 0,25668133 ! feeding behavior GO:0007631 59 40 0,000 0,23203736 0,25656337 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,23203736 0,25644552 ! mesenchymal cell development GO:0014031 87 40 0,000 0,23203736 0,25632778 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,23203736 0,25621014 ! maintenance of protein location GO:0045185 91 40 0,000 0,23203736 0,25609261 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,23709294 0,26155232 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,23709294 0,26143246 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,23709294 0,2613127 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,23709294 0,26119305 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,23709294 0,26107351 ! T cell differentiation GO:0030217 81 41 0,000 0,23709294 0,26095408 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,23709294 0,26083476 ! female gamete generation GO:0007292 61 41 0,000 0,23709294 0,26071555 ! polyol metabolic process GO:0019751 66 41 0,000 0,23709294 0,26059644 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,2421154 0,26599528 ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,2421154 0,26587388 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,2421154 0,26575258 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,2421154 0,2656314 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,2421154 0,26551033 ! neuron migration GO:0001764 79 42 0,000 0,2421154 0,26538937 ! regulation of protein secretion GO:0050708 71 42 0,000 0,2421154 0,26526852 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,24710497 0,270612 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,24710497 0,27048888 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,24710497 0,27036587 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,24710497 0,27024298 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,24710497 0,2701202 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,24710497 0,26999753 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,25206185 0,27528861 ! male sex differentiation GO:0046661 76 44 0,000 0,25206185 0,27516371 ! double-strand break repair GO:0006302 81 44 0,000 0,25206185 0,27503892 ! biopolymer methylation GO:0043414 84 44 0,000 0,25206185 0,27491424 ! B cell differentiation GO:0030183 107 44 0,000 0,25206185 0,27478967 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,25206185 0,27466522 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,25206185 0,27454088 ! maintenance of location in cell GO:0051651 97 44 0,000 0,25206185 0,27441666 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,25698626 0,27965126 ! glycolysis GO:0006096 65 45 0,000 0,25698626 0,27952484 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,25698626 0,27939853 ! leukocyte migration GO:0050900 68 45 0,000 0,25698626 0,27927233 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,25698626 0,27914625 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,25698626 0,27902028 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,25698626 0,27889442 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,25698626 0,27876868 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,25698626 0,27864305 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,26187841 0,28381957 ! regulation of gene-specific transcription GO:0032583 96 46 0,000 0,26187841 0,28369178 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,26187841 0,28356411 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,26187841 0,28343655 ! positive regulation of defense response GO:0031349 76 47 0,000 0,26673851 0,28856693 ! response to calcium ion GO:0051592 81 47 0,000 0,26673851 0,28843724 ! endosome transport GO:0016197 108 47 0,000 0,26673851 0,28830766 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,26673851 0,2881782 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,26673851 0,28804886 ! JNK cascade GO:0007254 91 47 0,000 0,26673851 0,28791963 ! methylation GO:0032259 90 47 0,000 0,26673851 0,28779052 ! protein homooligomerization GO:0051260 76 47 0,000 0,26673851 0,28766152 ! mitochondrial transport GO:0006839 82 48 0,000 0,27156677 0,2927373 ! Notch signaling pathway GO:0007219 96 48 0,000 0,27156677 0,2926062 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,27156677 0,29247522 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,27156677 0,29234436 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,27156677 0,29221362 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,27156677 0,29208299 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,2763634 0,29710917 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,2763634 0,29697648 ! regulation of ion transport GO:0043269 77 49 0,000 0,2763634 0,2968439 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,2763634 0,29671144 ! peptide metabolic process GO:0006518 76 49 0,000 0,2763634 0,29657909 ! response to temperature stimulus GO:0009266 76 49 0,000 0,2763634 0,29644687 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,2763634 0,29631476 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,2763634 0,29618277 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,2763634 0,2960509 GO:0019724|B cell mediated immunity, ! neuromuscular process GO:0050905 99 50 0,000 0,2811286 0,30102154 ! regulation of ossification GO:0030278 117 50 0,000 0,2811286 0,30088763 ! inner ear development GO:0048839 79 50 0,000 0,2811286 0,30075385 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,2811286 0,30062018 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,2811286 0,30048663 ! viral infectious cycle GO:0019058 99 51 0,000 0,28586257 0,3054109 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,28586257 0,30527535 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,28586257 0,30513991 ! excretion GO:0007588 83 51 0,000 0,28586257 0,30500459 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,28586257 0,30486939 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,28586257 0,30473432 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,28586257 0,30459936 ! vesicle organization GO:0016050 107 51 0,000 0,28586257 0,30446452 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,29056553 0,30933658 ! membrane fusion GO:0006944 110 52 0,000 0,29056553 0,30919977 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,29523768 0,31403265 ! RNA catabolic process GO:0006401 93 53 0,000 0,29523768 0,31389388 ! regulation of translational initiation GO:0006446 82 53 0,000 0,29523768 0,31375524 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,29523768 0,31361671 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,29523768 0,31347831 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,29523768 0,31334003 ! cell maturation GO:0048469 100 53 0,000 0,29523768 0,31320188 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,29523768 0,31306384 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,29523768 0,31292593 ! cell recognition GO:0008037 85 54 0,000 0,29987921 0,31770558 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,29987921 0,31756575 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,29987921 0,31742603 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,29987921 0,31728645 ! chloride transport GO:0006821 90 55 0,000 0,30449032 0,32202361 ! glucose catabolic process GO:0006007 82 55 0,000 0,30449032 0,32188212 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,30449032 0,32174076 ! heart morphogenesis GO:0003007 97 55 0,000 0,30449032 0,32159952 ! RNA elongation GO:0006354 79 55 0,000 0,30449032 0,32145841 ! nuclear export GO:0051168 97 55 0,000 0,30449032 0,32131742 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,30449032 0,32117655 ! regulation of actin filament length GO:0030832 105 56 0,000 0,30907122 0,32586562 ! sensory perception of smell GO:0007608 80 56 0,000 0,30907122 0,32572289 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,30907122 0,32558028 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,30907122 0,32543779 ! regulation of DNA replication GO:0006275 101 56 0,000 0,30907122 0,32529543 ! proton transport GO:0015992 94 56 0,000 0,30907122 0,32515319 ! maintenance of location GO:0051235 118 57 0,000 0,3136221 0,32979666 ! hydrogen transport GO:0006818 97 58 0,000 0,31814315 0,33440472 ! regulation of endocytosis GO:0030100 91 58 0,000 0,31814315 0,3342587 ! adult behavior GO:0030534 99 58 0,000 0,31814315 0,3341128 ! regulation of cellular component size GO:0032535 109 59 0,000 0,32263457 0,33868184 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,32263457 0,33853414 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,32263457 0,33838656 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,32263457 0,33823912 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,32709656 0,34276756 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,32709656 0,34261833 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,32709656 0,34246924 ! regulation of heart contraction GO:0008016 110 60 0,000 0,32709656 0,34232027 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,32709656 0,34217144 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,3315293 0,34665775 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,3315293 0,34650716 ! tRNA processing GO:0008033 89 61 0,000 0,3315293 0,3463567 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,3315293 0,34620637 ! viral reproductive process GO:0022415 126 62 0,000 0,33593298 0,35065282 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,33593298 0,35050076 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,3403078 0,35491139 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,3403078 0,35475762 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,3403078 0,35460397 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,3403078 0,35445047 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,34465395 0,3588219 ! cell redox homeostasis GO:0045454 102 64 0,000 0,34465395 0,3586667 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,34465395 0,35851163 ! single fertilization GO:0007338 75 64 0,000 0,34465395 0,3583567 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,34897161 0,36268928 ! germ cell development GO:0007281 118 65 0,000 0,34897161 0,36253268 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,34897161 0,36237621 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,35326096 0,36667207 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,35326096 0,36651396 ! extracellular matrix organization GO:0030198 133 66 0,000 0,35326096 0,36635598 ! secondary metabolic process GO:0019748 116 66 0,000 0,35326096 0,36619813 ! developmental maturation GO:0021700 116 66 0,000 0,35326096 0,36604042 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,35752219 0,37029634 ! activation of MAPK activity GO:0000187 115 67 0,000 0,35752219 0,370137 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,35752219 0,3699778 ! hexose catabolic process GO:0019320 104 67 0,000 0,35752219 0,36981874 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,35752219 0,36965982 ! activation of immune response GO:0002253 105 67 0,000 0,35752219 0,36950103 ! amino acid transport GO:0006865 125 68 0,000 0,36175549 0,37371563 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,36175549 0,37355524 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,36175549 0,37339498 ! viral reproduction GO:0016032 134 68 0,000 0,36175549 0,37323487 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,36175549 0,37307489 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,36596103 0,37725032 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,36596103 0,37708876 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,36596103 0,37692733 ! antigen processing and presentation GO:0019882 104 69 0,000 0,36596103 0,37676605 ! amine catabolic process GO:0009310 117 71 0,000 0,37428959 0,38517568 ! B cell activation GO:0042113 160 71 0,000 0,37428959 0,38501101 ! acute inflammatory response GO:0002526 113 72 0,000 0,37841295 0,38908614 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,37841295 0,38891993 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,38250928 0,39296214 ! fertilization GO:0009566 90 73 0,000 0,38250928 0,39279442 ! neurotransmitter transport GO:0006836 123 74 0,000 0,38657875 0,39680396 ! exocytosis GO:0006887 133 74 0,000 0,38657875 0,39663475 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,38657875 0,39646568 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,38657875 0,39629675 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,39062154 0,40027062 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,39062154 0,40010022 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,39062154 0,39992997 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,39463781 0,40387009 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,39463781 0,40369838 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,39463781 0,40352681 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,39862775 0,40743346 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,40259152 0,41131007 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,40259152 0,41113549 ! protein oligomerization GO:0051259 139 78 0,000 0,40259152 0,41096105 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,4065293 0,41480471 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,4065293 0,41462887 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,41044125 0,41844138 ! response to metal ion GO:0010038 140 80 0,000 0,41044125 0,41826415 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,41044125 0,41808707 ! inorganic anion transport GO:0015698 138 80 0,000 0,41044125 0,41791014 ! T cell activation GO:0042110 168 81 0,000 0,41432755 0,4216887 ! digestion GO:0007586 112 81 0,000 0,41432755 0,42151039 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,41818835 0,42525831 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,41818835 0,42507865 ! response to drug GO:0042493 143 82 0,000 0,41818835 0,42489914 ! response to nutrient GO:0007584 125 82 0,000 0,41818835 0,42471979 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,41818835 0,42454058 ! regulation of lyase activity GO:0051339 160 83 0,000 0,42202383 0,42825362 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,42583416 0,43193802 ! response to unfolded protein GO:0006986 131 85 0,000 0,42961949 0,43559397 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,42961949 0,43541048 ! amine biosynthetic process GO:0009309 138 86 0,000 0,43337999 0,43903674 ! response to inorganic substance GO:0010035 153 86 0,000 0,43337999 0,43885196 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,43337999 0,43866733 ! alcohol catabolic process GO:0046164 130 86 0,000 0,43337999 0,43848286 ! amine transport GO:0015837 155 86 0,000 0,43337999 0,43829855 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,43711582 0,44189104 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,43711582 0,44170544 ! cellular respiration GO:0045333 135 88 0,000 0,44082714 0,44526873 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,44082714 0,44508188 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,44082714 0,44489518 ! cellular defense response GO:0006968 114 89 0,000 0,44451412 0,44842808 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,44817691 0,45193363 ! sterol metabolic process GO:0016125 152 91 0,000 0,45181567 0,45541202 ! response to protein stimulus GO:0051789 149 91 0,000 0,45181567 0,45522131 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,45181567 0,45503076 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,45543055 0,45847946 ! vitamin metabolic process GO:0006766 139 92 0,000 0,45543055 0,45828771 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,45902172 0,4617083 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,45902172 0,46151536 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,46258932 0,46490806 ! female pregnancy GO:0007565 164 94 0,000 0,46258932 0,46471395 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,46613351 0,46807898 ! leukocyte differentiation GO:0002521 202 96 0,000 0,46965445 0,47141786 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,46965445 0,47122127 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! positive regulation of immune response GO:0050778 156 96 0,000 0,46965445 0,47102485 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,47315228 0,47433516 ! hormone metabolic process GO:0042445 157 97 0,000 0,47315228 0,4741376 ! response to virus GO:0009615 160 98 0,000 0,47662716 0,47742088 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,47662716 0,4772222 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,47662716 0,47702369 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,48007923 0,48027885 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,48007923 0,48007923