pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6485-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 5,000 2,098E-08 5,125E-05 ! negative regulation of ligase activity GO:0051352 116 68 5,000 3,96E-06 4,838E-03 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of B cell activation GO:0050869 14 6 2,000 4,49E-06 3,656E-03 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 7,821E-06 4,777E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 4,000 9,258E-06 4,524E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 5,000 9,509E-06 3,872E-03 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 1,246E-05 4,348E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 1,246E-05 3,804E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 3,000 1,328E-05 3,606E-03 ! negative regulation of phosphorylation GO:0042326 52 24 3,000 1,328E-05 3,245E-03 ! regulation of ligase activity GO:0051340 147 84 5,000 1,356E-05 3,011E-03 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 3,000 1,851E-05 3,768E-03 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of lymphocyte activation GO:0051250 55 27 3,000 2,162E-05 4,064E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 2,000 2,645E-05 4,616E-03 ! regulation of B cell activation GO:0050864 55 30 3,000 3,328E-05 5,421E-03 ! negative regulation of leukocyte activation GO:0002695 60 31 3,000 3,803E-05 5,807E-03 ! regulation of B cell proliferation GO:0030888 22 12 2,000 4,806E-05 6,906E-03 ! negative regulation of mast cell proliferation GO:0070667 24 12 2,000 4,806E-05 6,523E-03 GO:0042130|negative regulation of T cell proliferation, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 4,000 5,876E-05 7,555E-03 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 4,000 6,311E-05 7,709E-03 ! lung development GO:0030324 165 69 4,000 6,77E-05 7,876E-03 ! negative regulation of cell activation GO:0050866 69 37 3,000 7,756E-05 8,613E-03 ! cell cycle checkpoint GO:0000075 145 71 4,000 7,766E-05 8,248E-03 ! respiratory tube development GO:0030323 171 72 4,000 8,304E-05 8,453E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 4,000 8,304E-05 8,114E-03 ! respiratory system development GO:0060541 175 74 4,000 9,466E-05 8,894E-03 ! mitotic cell cycle checkpoint GO:0007093 76 39 3,000 9,567E-05 8,657E-03 ! N-terminal protein amino acid modification GO:0031365 30 15 2,000 9,805E-05 8,555E-03 ! pituitary gland development GO:0021983 30 16 2,000 1,201E-04 0,01012025 ! negative regulation of leukocyte proliferation GO:0070664 32 16 2,000 1,201E-04 9,783E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of intracellular protein transport GO:0033157 86 42 3,000 1,283E-04 0,01011353 ! negative regulation of cell cycle process GO:0010948 35 17 2,000 1,452E-04 0,01108645 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 2,000 1,452E-04 0,0107505 ! regulation of epithelial cell proliferation GO:0050678 122 45 3,000 1,684E-04 0,01209941 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 3,000 1,835E-04 0,01281157 ! embryonic organ morphogenesis GO:0048562 34 19 2,000 2,051E-04 0,01391623 ! regulation of lymphocyte differentiation GO:0045619 92 49 3,000 2,349E-04 0,0155106 ! regulation of mast cell proliferation GO:0070666 89 49 3,000 2,349E-04 0,01510243 ! regulation of cell cycle process GO:0010564 161 90 4,000 2,386E-04 0,01494351 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 2,000 2,402E-04 0,01466828 ! apoptotic mitochondrial changes GO:0008637 42 20 2,000 2,402E-04 0,01431052 ! negative regulation of T cell activation GO:0050868 41 20 2,000 2,402E-04 0,01396979 ! gland development GO:0048732 220 91 4,000 2,512E-04 0,01427055 ! endocrine system development GO:0035270 109 50 3,000 2,541E-04 0,01410945 ! negative regulation of immune system process GO:0002683 101 51 3,000 2,744E-04 0,01489852 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 4,000 2,779E-04 0,0147611 GO:0010498|proteasomal protein catabolic process, ! cell structure disassembly during apoptosis GO:0006921 32 21 2,000 2,789E-04 0,01449849 ! diencephalon development GO:0021536 36 21 2,000 2,789E-04 0,01419644 ! regulation of leukocyte proliferation GO:0070663 97 53 3,000 3,185E-04 0,01587976 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! apoptotic nuclear changes GO:0030262 34 22 2,000 3,215E-04 0,01570923 ! positive regulation of intracellular transport GO:0032388 42 22 2,000 3,215E-04 0,01540121 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 2,000 3,215E-04 0,01510503 ! interphase of mitotic cell cycle GO:0051329 224 98 4,000 3,543E-04 0,01633158 ! hemoglobin biosynthetic process GO:0042541 8 5 1,000 3,699E-04 0,0167355 ! negative regulation of bone resorption GO:0045779 10 5 1,000 3,699E-04 0,01643122 ! hypothalamus development GO:0021854 9 5 1,000 3,699E-04 0,0161378 ! apoptotic cell clearance GO:0043277 23 5 1,000 3,699E-04 0,01585469 ! lymph vessel development GO:0001945 10 5 1,000 3,699E-04 0,01558133 ! regulation of activin receptor signaling pathway GO:0032925 15 5 1,000 3,699E-04 0,01531724 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 3,699E-04 0,01506195 ! microvillus organization GO:0032528 8 5 1,000 3,699E-04 0,01481503 GO:0030033|microvillus assembly, ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 3,699E-04 0,01457608 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 1,000 3,699E-04 0,01434472 ! substrate-bound cell migration, cell extension GO:0006930 6 5 1,000 3,699E-04 0,01412058 ! meiotic chromosome segregation GO:0045132 10 5 1,000 3,699E-04 0,01390334 ! negative regulation of macrophage differentiation GO:0045650 7 5 1,000 3,699E-04 0,01369268 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 3,699E-04 0,01348831 ! protein insertion into membrane GO:0051205 17 5 1,000 3,699E-04 0,01328996 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 1,000 3,699E-04 0,01309735 GO:0022011|myelination in the peripheral nervous system, ! stem cell division GO:0017145 11 5 1,000 3,699E-04 0,01291024 GO:0048103|somatic stem cell division, ! DNA catabolic process, endonucleolytic GO:0000737 38 24 2,000 4,188E-04 0,01440883 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 4,215E-04 0,01430202 ! regulation of intracellular transport GO:0032386 108 57 3,000 4,215E-04 0,0141061 ! positive regulation of cell migration GO:0030335 137 58 3,000 4,506E-04 0,01487496 ! myelination GO:0042552 50 26 2,000 5,331E-04 0,01736453 ! myoblast cell fate commitment GO:0048625 18 6 1,000 5,526E-04 0,01776436 ! forebrain regionalization GO:0021871 9 6 1,000 5,526E-04 0,01753366 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 1,000 5,526E-04 0,01730886 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 1,000 5,526E-04 0,01708977 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 1,000 5,526E-04 0,01687614 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 1,000 5,526E-04 0,0166678 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! activation of MAPKKK activity GO:0000185 12 6 1,000 5,526E-04 0,01646453 ! vascular smooth muscle contraction GO:0014829 13 6 1,000 5,526E-04 0,01626616 ! paraxial mesoderm development GO:0048339 16 6 1,000 5,526E-04 0,01607252 ! establishment of spindle localization GO:0051293 16 6 1,000 5,526E-04 0,01588343 GO:0051653|spindle localization, ! astrocyte development GO:0014002 16 6 1,000 5,526E-04 0,01569874 ! Schwann cell development GO:0014044 15 6 1,000 5,526E-04 0,01551829 ! regulation of viral transcription GO:0046782 11 6 1,000 5,526E-04 0,01534195 ! ectodermal gut morphogenesis GO:0048567 16 6 1,000 5,526E-04 0,01516957 GO:0007439|ectodermal gut development, ! regulation of homeostatic process GO:0032844 148 62 3,000 5,812E-04 0,01577662 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 5,97E-04 0,01602779 ! regulation of chromosome organization GO:0033044 49 27 2,000 5,97E-04 0,01585357 ! regulation of mitosis GO:0007088 112 63 3,000 6,177E-04 0,01622511 GO:0051783|regulation of nuclear division, ! positive regulation of cell motion GO:0051272 157 65 3,000 6,954E-04 0,01807203 ! cellular iron ion homeostasis GO:0006879 57 29 2,000 7,391E-04 0,01900693 ! negative regulation of cellular catabolic process GO:0031330 12 7 1,000 7,706E-04 0,01960922 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 7,706E-04 0,01940706 ! mRNA stabilization GO:0048255 18 7 1,000 7,706E-04 0,01920903 GO:0043489|RNA stabilization, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 7,706E-04 0,019015 ! spinal cord patterning GO:0021511 14 7 1,000 7,706E-04 0,01882485 ! spindle checkpoint GO:0031577 16 7 1,000 7,706E-04 0,01863847 ! cranial nerve morphogenesis GO:0021602 12 7 1,000 7,706E-04 0,01845574 ! transcription from RNA polymerase I promoter GO:0006360 14 7 1,000 7,706E-04 0,01827655 ! negative regulation of nuclear division GO:0051784 15 7 1,000 7,706E-04 0,01810082 GO:0045839|negative regulation of mitosis, ! negative regulation of cell growth GO:0030308 142 67 3,000 7,797E-04 0,01814203 ! negative regulation of cell size GO:0045792 144 69 3,000 8,711E-04 0,02007656 ! negative regulation of protein kinase activity GO:0006469 144 69 3,000 8,711E-04 0,01988893 ! iron ion homeostasis GO:0055072 60 31 2,000 9,011E-04 0,0203823 ! ensheathment of neurons GO:0007272 64 31 2,000 9,011E-04 0,0201953 GO:0008366|axon ensheathment, ! negative regulation of kinase activity GO:0033673 145 70 3,000 9,195E-04 0,02042137 ! spindle organization GO:0007051 50 32 2,000 9,898E-04 0,02178446 ! peripheral nervous system development GO:0007422 68 32 2,000 9,898E-04 0,02158996 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 1,023E-03 0,02212244 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,023E-03 0,02192838 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,023E-03 0,0217377 ! hemoglobin metabolic process GO:0020027 14 8 1,000 1,023E-03 0,02155031 ! regulation of defense response to virus by virus GO:0050690 22 8 1,000 1,023E-03 0,02136612 ! astrocyte differentiation GO:0048708 19 8 1,000 1,023E-03 0,02118505 ! ER overload response GO:0006983 13 8 1,000 1,023E-03 0,02100702 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,023E-03 0,02083196 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 1,023E-03 0,0206598 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,023E-03 0,02049046 ! Schwann cell differentiation GO:0014037 21 8 1,000 1,023E-03 0,02032387 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 1,000 1,023E-03 0,02015996 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 1,023E-03 0,01999868 ! negative regulation of transferase activity GO:0051348 155 74 3,000 1,132E-03 0,02195022 ! cell fate specification GO:0001708 56 34 2,000 1,183E-03 0,02276458 ! telencephalon development GO:0021537 81 35 2,000 1,289E-03 0,02459315 ! cell proliferation in forebrain GO:0021846 18 9 1,000 1,31E-03 0,02481466 ! induction of positive chemotaxis GO:0050930 17 9 1,000 1,31E-03 0,02462377 ! cerebral cortex cell migration GO:0021795 18 9 1,000 1,31E-03 0,02443581 ! microtubule bundle formation GO:0001578 22 9 1,000 1,31E-03 0,02425069 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,31E-03 0,02406835 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,31E-03 0,02388874 ! regulation of macrophage differentiation GO:0045649 16 9 1,000 1,31E-03 0,02371178 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 1,000 1,31E-03 0,02353743 ! regulation of telomere maintenance GO:0032204 17 9 1,000 1,31E-03 0,02336562 ! negative regulation of DNA binding GO:0043392 67 36 2,000 1,399E-03 0,0247729 ! embryonic organ development GO:0048568 67 36 2,000 1,399E-03 0,02459468 ! negative regulation of organelle organization GO:0010639 181 80 3,000 1,512E-03 0,02638921 ! odontogenesis GO:0042476 74 37 2,000 1,516E-03 0,02626658 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,631E-03 0,02806484 ! smoothened signaling pathway GO:0007224 18 10 1,000 1,631E-03 0,02786858 ! lung alveolus development GO:0048286 26 10 1,000 1,631E-03 0,02767505 ! pathogenesis GO:0009405 17 10 1,000 1,631E-03 0,02748419 ! motor axon guidance GO:0008045 22 10 1,000 1,631E-03 0,02729594 ! regulation of bone resorption GO:0045124 25 10 1,000 1,631E-03 0,02711025 ! regulation of B cell differentiation GO:0045577 24 10 1,000 1,631E-03 0,02692707 ! spinal cord motor neuron differentiation GO:0021522 19 10 1,000 1,631E-03 0,02674636 ! induction of an organ GO:0001759 17 10 1,000 1,631E-03 0,02656805 ! positive regulation of viral reproduction GO:0048524 19 10 1,000 1,631E-03 0,0263921 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,631E-03 0,02621847 ! regulation of protein stability GO:0031647 77 38 2,000 1,639E-03 0,02616322 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 1,639E-03 0,02599333 ! negative regulation of binding GO:0051100 71 39 2,000 1,767E-03 0,02785211 ! negative regulation of growth GO:0045926 168 85 3,000 1,891E-03 0,02960641 ! mammary gland development GO:0030879 93 40 2,000 1,902E-03 0,02959334 ! nucleus organization GO:0006997 73 40 2,000 1,902E-03 0,02940604 ! regulation of action potential in neuron GO:0019228 80 40 2,000 1,902E-03 0,0292211 ! neuron fate specification GO:0048665 18 11 1,000 1,986E-03 0,0303197 ! telencephalon cell migration GO:0022029 23 11 1,000 1,986E-03 0,03013138 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 1,986E-03 0,02994538 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 1,986E-03 0,02976167 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,986E-03 0,02958019 ! blood vessel remodeling GO:0001974 30 11 1,000 1,986E-03 0,02940092 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 1,986E-03 0,0292238 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 1,986E-03 0,02904881 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 1,986E-03 0,0288759 ! negative regulation of proteolysis GO:0045861 25 11 1,000 1,986E-03 0,02870504 ! substrate-bound cell migration GO:0006929 14 11 1,000 1,986E-03 0,02853619 ! vasoconstriction GO:0042310 20 11 1,000 1,986E-03 0,02836931 ! nucleosome positioning GO:0016584 15 11 1,000 1,986E-03 0,02820437 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 1,986E-03 0,02804134 ! nitric oxide mediated signal transduction GO:0007263 26 11 1,000 1,986E-03 0,02788018 ! embryonic gut development GO:0048566 19 11 1,000 1,986E-03 0,02772087 ! regulation of hormone secretion GO:0046883 69 41 2,000 2,043E-03 0,02835485 ! regulation of protein transport GO:0051223 165 87 3,000 2,059E-03 0,02841404 GO:0070201|regulation of establishment of protein localization, ! regulation of T cell differentiation GO:0045580 78 42 2,000 2,19E-03 0,03005741 ! regulation of DNA binding GO:0051101 167 89 3,000 2,237E-03 0,03052808 ! glucose transport GO:0015758 66 43 2,000 2,344E-03 0,03180935 ! regulation of T cell proliferation GO:0042129 80 43 2,000 2,344E-03 0,03163361 ! regulation of positive chemotaxis GO:0050926 22 12 1,000 2,373E-03 0,03185659 GO:0050927|positive regulation of positive chemotaxis, ! ventral spinal cord development GO:0021517 25 12 1,000 2,373E-03 0,03168251 ! focal adhesion formation GO:0048041 37 12 1,000 2,373E-03 0,03151033 ! forebrain cell migration GO:0021885 24 12 1,000 2,373E-03 0,03134 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 1,000 2,373E-03 0,03117151 ! cranial nerve development GO:0021545 23 12 1,000 2,373E-03 0,03100481 ! histone acetylation GO:0016573 27 12 1,000 2,373E-03 0,03083989 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,373E-03 0,03067672 ! regulation of leukocyte migration GO:0002685 29 12 1,000 2,373E-03 0,03051526 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 2,373E-03 0,0303555 ! developmental induction GO:0031128 22 12 1,000 2,373E-03 0,0301974 GO:0045168|cell-cell signaling involved in cell fate specification, ! localization within membrane GO:0051668 26 12 1,000 2,373E-03 0,03004093 ! hexose transport GO:0008645 68 44 2,000 2,504E-03 0,03153133 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 2,000 2,504E-03 0,03136963 ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 2,671E-03 0,03328892 ! endocrine pancreas development GO:0031018 25 13 1,000 2,793E-03 0,03464182 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 1,000 2,793E-03 0,03446686 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 2,793E-03 0,03429366 ! regulation of erythrocyte differentiation GO:0045646 47 13 1,000 2,793E-03 0,03412219 ! regulation of mRNA stability GO:0043488 32 13 1,000 2,793E-03 0,03395243 ! digestive tract morphogenesis GO:0048546 31 13 1,000 2,793E-03 0,03378435 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 2,793E-03 0,03361792 ! cell growth GO:0016049 90 46 2,000 2,844E-03 0,03406152 ! positive regulation of protein transport GO:0051222 80 46 2,000 2,844E-03 0,03389537 ! response to insulin stimulus GO:0032868 98 47 2,000 3,025E-03 0,03586921 ! regulation of protein localization GO:0032880 188 97 3,000 3,056E-03 0,03606535 ! forebrain development GO:0030900 210 98 3,000 3,171E-03 0,0372422 ! positive regulation of cell cycle GO:0045787 96 48 2,000 3,212E-03 0,03754238 ! cellular component disassembly GO:0022411 89 48 2,000 3,212E-03 0,0373636 ! vascular process in circulatory system GO:0003018 85 48 2,000 3,212E-03 0,03718653 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 1,000 3,246E-03 0,03740453 GO:0060675|ureteric bud morphogenesis, ! bone mineralization GO:0030282 18 14 1,000 3,246E-03 0,03722892 ! regulation of RNA stability GO:0043487 33 14 1,000 3,246E-03 0,03705496 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 3,246E-03 0,03688261 ! response to calcium ion GO:0051592 94 49 2,000 3,406E-03 0,03852152 ! skeletal muscle tissue development GO:0007519 223 100 3,000 3,41E-03 0,03838489 GO:0060538|skeletal muscle organ development, ! regulation of action potential GO:0001508 102 50 2,000 3,607E-03 0,0404226 ! induction of apoptosis by extracellular signals GO:0008624 99 50 2,000 3,607E-03 0,04023802 ! activation of caspase activity GO:0006919 95 50 2,000 3,607E-03 0,04005512 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 3,73E-03 0,04123471 ! cardiac muscle contraction GO:0060048 28 15 1,000 3,73E-03 0,04104897 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 1,000 3,73E-03 0,04086489 ! regulation of mRNA processing GO:0050684 26 15 1,000 3,73E-03 0,04068246 ! response to hexose stimulus GO:0009746 25 15 1,000 3,73E-03 0,04050165 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 1,000 4,246E-03 0,04589727 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 4,246E-03 0,04569508 ! mRNA splice site selection GO:0006376 44 16 1,000 4,246E-03 0,04549466 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 4,246E-03 0,045296 ! biomineral formation GO:0031214 22 16 1,000 4,246E-03 0,04509906 ! response to UV GO:0009411 120 55 2,000 4,721E-03 0,04992979 ! negative regulation of hormone secretion GO:0046888 26 17 1,000 4,793E-03 0,05046775 ! endothelial cell migration GO:0043542 31 17 1,000 4,793E-03 0,05025115 ! glial cell development GO:0021782 28 17 1,000 4,793E-03 0,0500364 ! myoblast differentiation GO:0045445 50 17 1,000 4,793E-03 0,04982348 ! activation of MAPKK activity GO:0000186 43 17 1,000 4,793E-03 0,04961237 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 4,793E-03 0,04940303 ! regulation of survival gene product expression GO:0045884 38 17 1,000 4,793E-03 0,04919546 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 4,793E-03 0,04898962 GO:0031114|regulation of microtubule depolymerization, ! negative regulation of homeostatic process GO:0032845 36 17 1,000 4,793E-03 0,04878549 ! skeletal muscle fiber development GO:0048741 130 56 2,000 4,966E-03 0,050341 ! regulation of protein catabolic process GO:0042176 126 56 2,000 4,966E-03 0,05013298 ! positive regulation of caspase activity GO:0043280 108 57 2,000 5,219E-03 0,05246495 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 2,000 5,219E-03 0,05224993 ! limbic system development GO:0021761 40 18 1,000 5,37E-03 0,05354738 ! regulation of defense response to virus GO:0050688 35 18 1,000 5,37E-03 0,05332971 ! cell-substrate junction assembly GO:0007044 56 18 1,000 5,37E-03 0,0531138 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 5,37E-03 0,05289963 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 5,37E-03 0,05268718 ! nerve development GO:0021675 34 18 1,000 5,37E-03 0,05247644 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 5,37E-03 0,05226737 ! establishment of organelle localization GO:0051656 122 59 2,000 5,746E-03 0,05570795 ! positive regulation of hormone secretion GO:0046887 35 19 1,000 5,978E-03 0,05772172 ! cell differentiation in spinal cord GO:0021515 37 19 1,000 5,978E-03 0,05749447 ! cerebral cortex development GO:0021987 40 19 1,000 5,978E-03 0,057269 ! neuromuscular junction development GO:0007528 43 19 1,000 5,978E-03 0,05704529 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 5,978E-03 0,05682332 ! heart process GO:0003015 32 19 1,000 5,978E-03 0,05660308 GO:0060047|heart contraction, ! proximal/distal pattern formation GO:0009954 33 19 1,000 5,978E-03 0,05638453 ! DNA catabolic process GO:0006308 94 60 2,000 6,022E-03 0,05658198 ! camera-type eye development GO:0043010 126 61 2,000 6,305E-03 0,05901613 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 6,615E-03 0,0616833 ! protein amino acid acetylation GO:0006473 41 20 1,000 6,615E-03 0,06144876 ! response to alkaloid GO:0043279 38 20 1,000 6,615E-03 0,061216 ! pancreas development GO:0031016 40 20 1,000 6,615E-03 0,06098499 ! response to carbohydrate stimulus GO:0009743 33 20 1,000 6,615E-03 0,06075573 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 6,615E-03 0,06052818 ! actin filament bundle formation GO:0051017 47 20 1,000 6,615E-03 0,06030233 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 6,615E-03 0,06007815 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 1,000 6,615E-03 0,05985564 ! skeletal system morphogenesis GO:0048705 118 63 2,000 6,895E-03 0,06215679 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 7,202E-03 0,0646843 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 7,202E-03 0,06444736 ! lipid phosphorylation GO:0046834 43 21 1,000 7,282E-03 0,06492867 ! ovarian follicle development GO:0001541 39 21 1,000 7,282E-03 0,06469256 ! smooth muscle contraction GO:0006939 48 21 1,000 7,282E-03 0,06445817 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 1,000 7,282E-03 0,06422547 ! negative regulation of intracellular transport GO:0032387 44 21 1,000 7,282E-03 0,06399444 ! camera-type eye morphogenesis GO:0048593 47 21 1,000 7,282E-03 0,06376507 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 7,978E-03 0,06961055 ! hindlimb morphogenesis GO:0035137 47 22 1,000 7,978E-03 0,06936282 ! ureteric bud development GO:0001657 50 22 1,000 7,978E-03 0,06911686 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 7,978E-03 0,06887263 ! positive regulation of locomotion GO:0040017 44 22 1,000 7,978E-03 0,06863012 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! peptidyl-serine modification GO:0018209 50 22 1,000 7,978E-03 0,06838931 ! positive regulation of B cell activation GO:0050871 42 22 1,000 7,978E-03 0,06815019 ! gut development GO:0048565 44 22 1,000 7,978E-03 0,06791273 ! cell projection assembly GO:0030031 138 68 2,000 8,51E-03 0,07218311 ! regulation of chemotaxis GO:0050920 45 23 1,000 8,703E-03 0,07356954 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 8,703E-03 0,07331585 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 8,703E-03 0,0730639 ! vesicle targeting GO:0006903 49 23 1,000 8,703E-03 0,07281369 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 1,000 8,703E-03 0,07256518 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 2,000 8,857E-03 0,07359506 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 9,456E-03 0,07831006 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 9,456E-03 0,07804549 ! regulation of viral reproduction GO:0050792 41 24 1,000 9,456E-03 0,07778271 ! pallium development GO:0021543 56 24 1,000 9,456E-03 0,0775217 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 9,456E-03 0,07726243 ! negative regulation of catabolic process GO:0009895 52 24 1,000 9,456E-03 0,07700489 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 9,456E-03 0,07674906 ! appendage morphogenesis GO:0035107 150 72 2,000 9,948E-03 0,08047053 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 2,000 9,948E-03 0,08020495 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 2,000 9,948E-03 0,07994112 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 0,01023727 0,08199887 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 0,01023727 0,0817309 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 0,01023727 0,08146468 ! vasculogenesis GO:0001570 49 25 1,000 0,01023727 0,08120018 ! regulation of insulin secretion GO:0050796 42 25 1,000 0,01023727 0,0809374 ! regulation of behavior GO:0050795 48 25 1,000 0,01023727 0,08067631 ! appendage development GO:0048736 151 73 2,000 0,01032786 0,08112849 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 136 74 2,000 0,01071641 0,08391088 ! organelle localization GO:0051640 155 74 2,000 0,01071641 0,0836428 ! spinal cord development GO:0021510 54 26 1,000 0,01104595 0,08594034 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 0,01104595 0,08566751 ! positive regulation of nuclear division GO:0051785 41 26 1,000 0,01104595 0,08539641 GO:0045840|positive regulation of mitosis, ! regulation of multi-organism process GO:0043900 45 26 1,000 0,01104595 0,08512702 ! regulation of transcription factor activity GO:0051090 137 75 2,000 0,01111334 0,08537699 GO:0090046|regulation of transcription regulator activity, ! phosphoinositide-mediated signaling GO:0048015 141 75 2,000 0,01111334 0,08510936 ! eye development GO:0001654 155 75 2,000 0,01111334 0,08484339 ! axon guidance GO:0007411 162 75 2,000 0,01111334 0,08457908 ! regulation of interferon-gamma production GO:0032649 43 27 1,000 0,01188187 0,09014722 ! iron ion transport GO:0006826 65 27 1,000 0,01188187 0,08986812 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 1,000 0,01188187 0,08959075 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 0,01188187 0,08931509 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 0,01193243 0,08941999 ! positive regulation of ligase activity GO:0051351 130 77 2,000 0,01193243 0,08914653 ! regulation of catabolic process GO:0009894 173 77 2,000 0,01193243 0,08887475 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 0,01274465 0,09463584 ! neuron fate commitment GO:0048663 52 28 1,000 0,01274465 0,09434906 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 0,01274465 0,09406402 ! protein amino acid acylation GO:0043543 59 28 1,000 0,01274465 0,09378069 ! dendrite development GO:0016358 67 28 1,000 0,01274465 0,09349907 ! regulation of response to biotic stimulus GO:0002831 52 28 1,000 0,01274465 0,09321913 ! activation of protein kinase activity GO:0032147 170 80 2,000 0,01322456 0,09644058 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 0,01363395 0,0991302 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 0,01363395 0,09883605 ! regulation of peptide secretion GO:0002791 52 29 1,000 0,01363395 0,09854363 ! somitogenesis GO:0001756 52 29 1,000 0,01363395 0,09825294 ! response to hypoxia GO:0001666 178 81 2,000 0,0136723 0,09823949 ! regulation of peptidase activity GO:0052547 150 82 2,000 0,01412859 0,10122038 ! protein import into nucleus GO:0006606 174 82 2,000 0,01412859 0,10092441 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 1,000 0,01454941 0,10362744 ! positive regulation of multicellular organism growth GO:0040018 55 30 1,000 0,01454941 0,1033262 ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 0,01454941 0,1030267 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 1,000 0,01454941 0,10272894 GO:0048871|multicellular organismal homeostasis, ! response to oxygen levels GO:0070482 183 83 2,000 0,01459346 0,10274298 ! intracellular protein transmembrane transport GO:0065002 165 83 2,000 0,01459346 0,10244775 ! nuclear import GO:0051170 177 83 2,000 0,01459346 0,1021542 ! response to metal ion GO:0010038 158 84 2,000 0,01506691 0,10516705 ! cell junction assembly GO:0034329 85 31 1,000 0,01549068 0,10781688 ! ovulation cycle process GO:0022602 55 31 1,000 0,01549068 0,10751058 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 0,01549068 0,10720602 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 0,01549068 0,10690317 ! eye morphogenesis GO:0048592 65 31 1,000 0,01549068 0,10660204 ! negative regulation of transport GO:0051051 164 85 2,000 0,01554897 0,10670265 ! cellular response to hormone stimulus GO:0032870 182 85 2,000 0,01554897 0,10640377 ! metanephros development GO:0001656 81 32 1,000 0,0164574 0,11230568 ! response to mechanical stimulus GO:0009612 60 32 1,000 0,0164574 0,11199285 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 0,0164574 0,11168176 ! mesoderm formation GO:0001707 73 32 1,000 0,0164574 0,11137239 ! ovulation cycle GO:0042698 57 32 1,000 0,0164574 0,11106473 ! hindbrain development GO:0030902 65 32 1,000 0,0164574 0,11075877 ! positive regulation of catabolic process GO:0009896 72 32 1,000 0,0164574 0,11045449 ! mitochondrion organization GO:0007005 159 87 2,000 0,01653898 0,11069789 ! regulation of axonogenesis GO:0050770 86 33 1,000 0,01744924 0,11647131 ! negative regulation of protein transport GO:0051224 74 33 1,000 0,01744924 0,11615395 ! establishment of vesicle localization GO:0051650 67 33 1,000 0,01744924 0,11583831 ! protein localization in nucleus GO:0034504 192 89 2,000 0,01756359 0,11628141 ! response to inorganic substance GO:0010035 173 90 2,000 0,01808889 0,11943556 ! glial cell differentiation GO:0010001 67 34 1,000 0,01846586 0,12159592 ! spliceosome assembly GO:0000245 75 34 1,000 0,01846586 0,12126905 ! formation of primary germ layer GO:0001704 76 34 1,000 0,01846586 0,12094393 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,01846586 0,12062055 ! ossification GO:0001503 205 91 2,000 0,01862288 0,12132183 ! bone development GO:0060348 206 92 2,000 0,01916555 0,1245251 ! regulation of cell adhesion GO:0030155 241 92 2,000 0,01916555 0,12419479 ! negative regulation of secretion GO:0051048 68 35 1,000 0,01950691 0,12607241 ! regulation of synaptic plasticity GO:0048167 78 35 1,000 0,01950691 0,12573976 ! mesoderm morphogenesis GO:0048332 80 35 1,000 0,01950691 0,12540887 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,01950691 0,12507971 ! vesicle localization GO:0051648 70 35 1,000 0,01950691 0,12475228 ! regulation of cell morphogenesis GO:0022604 243 93 2,000 0,01971692 0,12576614 ! positive regulation of MAP kinase activity GO:0043406 174 93 2,000 0,01971692 0,12543863 ! regulation of membrane potential GO:0042391 179 94 2,000 0,02027699 0,12866671 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,02057205 0,13020085 ! protein targeting to membrane GO:0006612 75 36 1,000 0,02057205 0,12986442 ! regulation of proteolysis GO:0030162 77 36 1,000 0,02057205 0,12952971 ! regulation of T cell activation GO:0050863 175 96 2,000 0,02142325 0,13454239 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 0,02166097 0,13568655 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,02166097 0,13533952 ! sister chromatid segregation GO:0000819 65 37 1,000 0,02166097 0,13499427 ! cell junction organization GO:0034330 96 37 1,000 0,02166097 0,13465077 ! tissue remodeling GO:0048771 78 37 1,000 0,02166097 0,13430902 ! female gonad development GO:0008585 71 37 1,000 0,02166097 0,133969 ! regulation of microtubule-based process GO:0032886 86 37 1,000 0,02166097 0,13363069 ! transcription initiation GO:0006352 171 97 2,000 0,02200944 0,13543843 ! meiosis I GO:0007127 74 38 1,000 0,02277333 0,13978704 ! embryonic skeletal system morphogenesis GO:0048704 68 38 1,000 0,02277333 0,1394367 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 1,000 0,02277333 0,1390881 ! glycogen metabolic process GO:0005977 63 38 1,000 0,02277333 0,13874125 ! mRNA transport GO:0051028 185 100 2,000 0,02382028 0,14475854 ! regulation of neuron projection development GO:0010975 102 39 1,000 0,0239088 0,14493597 ! carbohydrate homeostasis GO:0033500 59 39 1,000 0,0239088 0,14457722 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,0239088 0,14422024 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 1,000 0,0239088 0,14386502 ! glucan metabolic process GO:0044042 64 39 1,000 0,0239088 0,14351154 GO:0006073|cellular glucan metabolic process, ! learning GO:0007612 82 40 1,000 0,02506706 0,15009517 ! development of primary female sexual characteristics GO:0046545 80 40 1,000 0,02506706 0,14972819 GO:0046660|female sex differentiation, ! gliogenesis GO:0042063 91 41 1,000 0,02624779 0,15639845 ! ear morphogenesis GO:0042471 64 42 1,000 0,02745068 0,16316793 ! dorsal/ventral pattern formation GO:0009953 75 42 1,000 0,02745068 0,16277189 ! cytokinesis GO:0000910 84 42 1,000 0,02745068 0,16237777 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,02867541 0,16921265 GO:0090047|positive regulation of transcription regulator activity, ! regulation of tube size GO:0035150 76 43 1,000 0,02867541 0,16880491 GO:0050880|regulation of blood vessel size, ! segmentation GO:0035282 78 43 1,000 0,02867541 0,16839913 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 0,02867541 0,16799529 ! energy reserve metabolic process GO:0006112 76 44 1,000 0,02992168 0,17487716 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,02992168 0,17445979 ! positive regulation of response to external stimulus GO:0032103 88 44 1,000 0,02992168 0,17404441 ! striated muscle contraction GO:0006941 85 44 1,000 0,02992168 0,17363101 ! phagocytosis GO:0006909 105 44 1,000 0,02992168 0,17321956 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,03029403 0,17496058 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,03029403 0,17454793 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,03029403 0,17413723 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03029403 0,17372846 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,03029403 0,1733216 ! neuron fate determination GO:0048664 7 5 0,000 0,03029403 0,17291664 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03029403 0,17251358 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,03029403 0,17211238 ! polyol transport GO:0015791 12 5 0,000 0,03029403 0,17171305 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03029403 0,17131556 ! response to superoxide GO:0000303 10 5 0,000 0,03029403 0,17091992 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,03029403 0,17052609 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,03029403 0,17013408 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03029403 0,16974386 ! female meiosis GO:0007143 10 5 0,000 0,03029403 0,16935543 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,03029403 0,16896878 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03029403 0,16858388 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,03029403 0,16820074 ! cobalt ion transport GO:0006824 11 5 0,000 0,03029403 0,16781933 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,03029403 0,16743965 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,03029403 0,16706168 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03029403 0,16668541 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,03029403 0,16631084 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,03029403 0,16593795 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,03029403 0,16556672 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03029403 0,16519715 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03029403 0,16482923 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,03029403 0,16446294 ! transposition GO:0032196 9 5 0,000 0,03029403 0,16409828 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,03029403 0,16373523 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,03029403 0,16337378 ! negative chemotaxis GO:0050919 16 5 0,000 0,03029403 0,16301393 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,03029403 0,16265566 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03029403 0,16229896 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,03029403 0,16194382 ! behavioral response to pain GO:0048266 10 5 0,000 0,03029403 0,16159023 ! clathrin coat assembly GO:0048268 15 5 0,000 0,03029403 0,16123818 ! Notch receptor processing GO:0007220 11 5 0,000 0,03029403 0,16088766 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03029403 0,16053866 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,03029403 0,16019118 ! micturition GO:0060073 9 5 0,000 0,03029403 0,15984519 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03029403 0,1595007 ! copulation GO:0007620 9 5 0,000 0,03029403 0,15915769 ! glial cell fate commitment GO:0021781 14 5 0,000 0,03029403 0,15881615 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,03029403 0,15847607 ! bioluminescence GO:0008218 9 5 0,000 0,03029403 0,15813744 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03029403 0,15780026 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03029403 0,15746452 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03029403 0,1571302 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03029403 0,1567973 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,03029403 0,1564658 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03029403 0,1561357 ! grooming behavior GO:0007625 6 5 0,000 0,03029403 0,155807 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,03029403 0,15547967 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,03029403 0,15515372 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,03029403 0,15482913 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03029403 0,1545059 ! response to protozoan GO:0001562 13 5 0,000 0,03029403 0,15418401 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,03029403 0,15386346 ! endochondral ossification GO:0001958 17 5 0,000 0,03029403 0,15354424 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03029403 0,15322634 ! single strand break repair GO:0000012 8 5 0,000 0,03029403 0,15290976 ! parathyroid gland development GO:0060017 14 5 0,000 0,03029403 0,15259448 ! anagen GO:0042640 7 5 0,000 0,03029403 0,1522805 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,03029403 0,15196781 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,03029403 0,1516564 ! cytokine secretion GO:0050663 15 5 0,000 0,03029403 0,15134627 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,03029403 0,1510374 ! ceramide catabolic process GO:0046514 7 5 0,000 0,03029403 0,15072978 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,03029403 0,15042342 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,03029403 0,1501183 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03029403 0,14981442 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03029403 0,14951177 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,03029403 0,14921033 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,03029403 0,14891011 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03029403 0,14861109 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,03029403 0,14831327 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,03029403 0,14801665 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,03029403 0,14772121 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,03029403 0,14742694 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03029403 0,14713384 ! valine metabolic process GO:0006573 12 5 0,000 0,03029403 0,14684191 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,03029403 0,14655114 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,03029403 0,14626151 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,03029403 0,14597303 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,03029403 0,14568568 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,03029403 0,14539946 ! polyol catabolic process GO:0046174 9 5 0,000 0,03029403 0,14511436 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,03029403 0,14483038 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,03029403 0,14454751 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,03029403 0,14426574 ! muscle cell migration GO:0014812 8 5 0,000 0,03029403 0,14398507 ! mitochondrial fission GO:0000266 8 5 0,000 0,03029403 0,14370548 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,03029403 0,14342698 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,03029403 0,14314956 ! mRNA transcription GO:0009299 10 5 0,000 0,03029403 0,14287321 ! nerve growth factor processing GO:0032455 9 5 0,000 0,03029403 0,14259793 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,03029403 0,1423237 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,03029403 0,14205053 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,03029403 0,1417784 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,03029403 0,14150731 ! monocyte activation GO:0042117 10 5 0,000 0,03029403 0,14123726 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03029403 0,14096824 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03029403 0,14070024 ! response to food GO:0032094 6 5 0,000 0,03029403 0,14043325 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,03029403 0,14016728 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03029403 0,13990231 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,03029403 0,13963835 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03029403 0,13937537 ! forebrain neuron development GO:0021884 13 5 0,000 0,03029403 0,13911339 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03029403 0,13885239 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,03029403 0,13859237 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03029403 0,13833332 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,03029403 0,13807523 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,03029403 0,13781811 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,03029403 0,13756194 ! lipid glycosylation GO:0030259 7 5 0,000 0,03029403 0,13730672 ! nucleobase transport GO:0015851 6 5 0,000 0,03029403 0,13705245 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03029403 0,13679912 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,03029403 0,13654672 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,03029403 0,13629526 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,03029403 0,13604471 ! basic amino acid transport GO:0015802 12 5 0,000 0,03029403 0,13579509 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,03029403 0,13554638 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,03029403 0,13529858 ! actin nucleation GO:0045010 11 5 0,000 0,03029403 0,13505169 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03029403 0,13480569 ! depurination GO:0045007 5 5 0,000 0,03029403 0,13456059 ! depyrimidination GO:0045008 10 5 0,000 0,03029403 0,13431638 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,03029403 0,13407305 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03029403 0,1338306 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,03029403 0,13358903 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,03029403 0,13334833 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,03029403 0,1331085 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,03029403 0,13286952 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03029403 0,13263141 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03029403 0,13239414 ! activated T cell proliferation GO:0050798 16 5 0,000 0,03029403 0,13215772 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03029403 0,13192215 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,03029403 0,13168741 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03029403 0,13145351 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03029403 0,13122043 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,03029403 0,13098818 ! response to arsenic GO:0046685 11 5 0,000 0,03029403 0,13075676 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,03029403 0,13052614 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,03029403 0,13029635 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,03029403 0,13006735 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,03029403 0,12983916 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,03029403 0,12961178 ! response to mercury ion GO:0046689 8 5 0,000 0,03029403 0,12938518 ! response to cadmium ion GO:0046686 7 5 0,000 0,03029403 0,12915938 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,03029403 0,12893436 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,03029403 0,12871013 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,03029403 0,12848667 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,03029403 0,12826399 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,03029403 0,12804208 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,03029403 0,12782094 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03029403 0,12760056 ! decidualization GO:0046697 11 5 0,000 0,03029403 0,12738094 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,03029403 0,12716207 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,03029403 0,12694395 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,03029403 0,12672658 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,03029403 0,12650996 ! embryonic cleavage GO:0040016 6 5 0,000 0,03029403 0,12629407 ! peroxisome fission GO:0016559 5 5 0,000 0,03029403 0,12607892 ! histone demethylation GO:0016577 13 5 0,000 0,03029403 0,1258645 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,03029403 0,1256508 ! mitotic recombination GO:0006312 9 5 0,000 0,03029403 0,12543784 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,03029403 0,12522559 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03029403 0,12501406 ! metaphase plate congression GO:0051310 7 5 0,000 0,03029403 0,12480324 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03029403 0,12459314 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,03029403 0,12438374 ! enteric nervous system development GO:0048484 8 5 0,000 0,03029403 0,12417504 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,03029403 0,12396704 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,03029403 0,12375974 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,03029403 0,12355313 ! muscle cell proliferation GO:0033002 12 5 0,000 0,03029403 0,12334721 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03029403 0,12314197 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,03029403 0,12293742 ! B cell homeostasis GO:0001782 13 5 0,000 0,03029403 0,12273354 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,03029403 0,12253034 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03029403 0,12232781 ! metaphase GO:0051323 11 5 0,000 0,03029403 0,12212595 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,03029403 0,12192475 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,03029403 0,12172422 ! cellular response to nutrient GO:0031670 8 5 0,000 0,03029403 0,12152434 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03029403 0,12132512 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,03029403 0,12112655 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,03029403 0,12092863 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,03029403 0,12073136 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,03029403 0,12053473 ! response to redox state GO:0051775 6 5 0,000 0,03029403 0,12033874 GO:0006980|redox signal response, ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,03029403 0,12014338 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,03029403 0,11994866 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,03029403 0,11975457 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,03029403 0,11956111 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03029403 0,11936826 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,03029403 0,11917605 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03029403 0,11898444 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,03029403 0,11879346 ! striatum development GO:0021756 14 5 0,000 0,03029403 0,11860308 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,03029403 0,11841332 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03029403 0,11822416 ! glial cell migration GO:0008347 10 5 0,000 0,03029403 0,1180356 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,03029403 0,11784765 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,03029403 0,11766029 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,03029403 0,11747353 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03029403 0,11728736 ! T cell activation during immune response GO:0002286 9 5 0,000 0,03029403 0,11710178 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,03029403 0,11691678 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03029403 0,11673237 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,03029403 0,11654854 ! neuroprotection GO:0043526 8 5 0,000 0,03029403 0,11636529 ! regulation of sensory perception GO:0051931 8 5 0,000 0,03029403 0,11618261 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03029403 0,11600051 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,03029403 0,11581897 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,03029403 0,11563801 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,03029403 0,1154576 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03029403 0,11527776 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,03029403 0,11509848 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03029403 0,11491976 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,03029403 0,11474159 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,03029403 0,11456397 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03029403 0,1143869 ! spindle assembly GO:0051225 6 5 0,000 0,03029403 0,11421038 ! receptor biosynthetic process GO:0032800 7 5 0,000 0,03029403 0,1140344 ! protein palmitoylation GO:0018345 12 5 0,000 0,03029403 0,11385896 ! drug metabolic process GO:0017144 7 5 0,000 0,03029403 0,11368406 ! phospholipid scrambling GO:0017121 8 5 0,000 0,03029403 0,1135097 ! organ regeneration GO:0031100 7 5 0,000 0,03029403 0,11333587 ! carnitine metabolic process GO:0009437 8 5 0,000 0,03029403 0,11316257 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03029403 0,11298981 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 0,03118916 0,1161511 ! developmental growth GO:0048589 88 45 1,000 0,03118916 0,11597431 ! pigmentation GO:0043473 103 46 1,000 0,03247756 0,1205816 ! neural tube development GO:0021915 91 47 1,000 0,03378659 0,12525134 ! regulation of JNK cascade GO:0046328 104 47 1,000 0,03378659 0,12506156 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 1,000 0,03511593 0,12978549 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,03511593 0,12958944 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03624231 0,13354445 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03624231 0,13334333 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03624231 0,13314281 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03624231 0,1329429 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03624231 0,13274358 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03624231 0,13254487 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03624231 0,13234674 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03624231 0,13214921 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03624231 0,13195227 ! response to oxygen radical GO:0000305 11 6 0,000 0,03624231 0,13175591 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03624231 0,13156013 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03624231 0,13136494 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03624231 0,13117033 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03624231 0,13097629 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03624231 0,13078282 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03624231 0,13058993 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03624231 0,1303976 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03624231 0,13020584 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03624231 0,13001464 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03624231 0,129824 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03624231 0,12963392 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03624231 0,1294444 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03624231 0,12925543 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03624231 0,12906701 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03624231 0,12887914 ! malate metabolic process GO:0006108 13 6 0,000 0,03624231 0,12869182 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03624231 0,12850504 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03624231 0,1283188 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03624231 0,1281331 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03624231 0,12794793 ! protein refolding GO:0042026 15 6 0,000 0,03624231 0,12776331 ! opsonization GO:0008228 8 6 0,000 0,03624231 0,12757921 ! mating behavior GO:0007617 7 6 0,000 0,03624231 0,12739564 ! erythrocyte maturation GO:0043249 8 6 0,000 0,03624231 0,1272126 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,03624231 0,12703009 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03624231 0,1268481 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,03624231 0,12666662 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,03624231 0,12648567 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03624231 0,12630524 ! response to interferon-gamma GO:0034341 16 6 0,000 0,03624231 0,12612531 ! toxin metabolic process GO:0009404 11 6 0,000 0,03624231 0,1259459 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03624231 0,125767 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,03624231 0,12558861 ! nuclear migration GO:0007097 13 6 0,000 0,03624231 0,12541072 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03624231 0,12523334 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03624231 0,12505646 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03624231 0,12488007 ! thymic T cell selection GO:0045061 16 6 0,000 0,03624231 0,12470418 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03624231 0,12452879 ! protein lipoylation GO:0009249 10 6 0,000 0,03624231 0,12435389 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03624231 0,12417948 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,03624231 0,12400556 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03624231 0,12383213 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,03624231 0,12365918 ! glutamate catabolic process GO:0006538 12 6 0,000 0,03624231 0,12348671 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03624231 0,12331472 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03624231 0,12314321 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,03624231 0,12297218 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03624231 0,12280162 ! hyperosmotic response GO:0006972 10 6 0,000 0,03624231 0,12263154 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,03624231 0,12246192 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03624231 0,12229278 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03624231 0,1221241 ! urea metabolic process GO:0019627 7 6 0,000 0,03624231 0,12195588 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03624231 0,12178813 ! neutrophil activation GO:0042119 7 6 0,000 0,03624231 0,12162084 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03624231 0,12145401 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,03624231 0,12128763 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03624231 0,12112171 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03624231 0,12095624 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03624231 0,12079123 ! neuron apoptosis GO:0051402 15 6 0,000 0,03624231 0,12062666 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03624231 0,12046254 ! T cell mediated immunity GO:0002456 17 6 0,000 0,03624231 0,12029887 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03624231 0,12013565 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,03624231 0,11997286 ! carnitine transport GO:0015879 10 6 0,000 0,03624231 0,11981051 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03624231 0,11964861 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03624231 0,11948714 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03624231 0,11932611 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,03624231 0,11916551 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,03624231 0,11900534 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03624231 0,1188456 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03624231 0,11868629 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,03624231 0,1185274 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,03624231 0,11836894 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03624231 0,11821091 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03624231 0,11805329 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,03624231 0,1178961 ! response to UV-C GO:0010225 14 6 0,000 0,03624231 0,11773932 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03624231 0,11758296 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03624231 0,11742702 ! interaction with symbiont GO:0051702 14 6 0,000 0,03624231 0,11727148 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03624231 0,11711636 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03624231 0,11696165 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,03624231 0,11680735 ! response to copper ion GO:0046688 10 6 0,000 0,03624231 0,11665345 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,03624231 0,11649996 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,03624231 0,11634687 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03624231 0,11619419 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,03624231 0,1160419 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03624231 0,11589001 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03624231 0,11573852 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03624231 0,11558743 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,03624231 0,11543673 ! hair follicle maturation GO:0048820 8 6 0,000 0,03624231 0,11528642 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03624231 0,1151365 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03624231 0,11498697 ! response to pheromone GO:0019236 6 6 0,000 0,03624231 0,11483783 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,03624231 0,11468908 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,03624231 0,11454071 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,03624231 0,11439273 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,03624231 0,11424512 ! subpallium development GO:0021544 15 6 0,000 0,03624231 0,1140979 ! neural tube patterning GO:0021532 8 6 0,000 0,03624231 0,11395106 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03624231 0,11380459 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03624231 0,1136585 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03624231 0,11351278 ! G2 phase GO:0051319 16 6 0,000 0,03624231 0,11336744 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03624231 0,11322247 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03624231 0,11307787 ! oxygen homeostasis GO:0032364 10 6 0,000 0,03624231 0,11293364 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03624231 0,11278977 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03624231 0,11264627 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03624231 0,11250314 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03624231 0,11236037 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03624231 0,11221796 ! receptor internalization GO:0031623 11 6 0,000 0,03624231 0,11207591 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,03624231 0,11193422 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,03624231 0,11179289 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,03624231 0,11165192 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03624231 0,1115113 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,03624231 0,11137103 ! protein deubiquitination GO:0016579 16 6 0,000 0,03624231 0,11123112 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,03624231 0,11109156 ! protein destabilization GO:0031648 9 6 0,000 0,03624231 0,11095234 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03624231 0,11081348 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03624231 0,11067496 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03624231 0,11053679 ! progesterone metabolic process GO:0042448 12 6 0,000 0,03624231 0,11039897 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,03624231 0,11026148 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,03624231 0,11012434 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03624231 0,10998754 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03624231 0,10985108 ! determination of adult lifespan GO:0008340 17 6 0,000 0,03624231 0,10971496 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03624231 0,10957917 ! neural plate development GO:0001840 9 6 0,000 0,03624231 0,10944372 ! catecholamine transport GO:0051937 9 6 0,000 0,03624231 0,10930861 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,03624231 0,10917382 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03624231 0,10903937 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,03624231 0,10890525 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,03624231 0,10877146 ! maternal placenta development GO:0001893 12 6 0,000 0,03624231 0,108638 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,03624231 0,10850487 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03624231 0,10837206 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,03624231 0,10823957 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03624231 0,10810741 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03624231 0,10797557 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,03624231 0,10784406 GO:0055081|anion homeostasis, ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,03646529 0,10837555 ! regulation of cell projection organization GO:0031344 135 51 1,000 0,03922291 0,11642961 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,03922291 0,11628831 ! positive regulation of binding GO:0051099 88 52 1,000 0,04063059 0,1203158 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,04063059 0,12017014 ! histone modification GO:0016570 104 52 1,000 0,04063059 0,12002483 ! ribonucleoprotein complex assembly GO:0022618 104 52 1,000 0,04063059 0,11987987 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 0,04063059 0,11973527 ! amino acid activation GO:0043038 98 52 1,000 0,04063059 0,11959101 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of growth GO:0045927 96 53 1,000 0,04205714 0,12364091 ! chromatin remodeling GO:0006338 122 53 1,000 0,04205714 0,1234923 ! cartilage development GO:0051216 99 53 1,000 0,04205714 0,12334405 ! synapse organization GO:0050808 102 53 1,000 0,04205714 0,12319616 ! tRNA transcription GO:0009304 17 7 0,000 0,04215427 0,1233328 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,04215427 0,12318527 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,04215427 0,12303809 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04215427 0,12289127 ! regulation of helicase activity GO:0051095 16 7 0,000 0,04215427 0,1227448 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,04215427 0,12259867 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,04215427 0,1224529 ! sleep GO:0030431 16 7 0,000 0,04215427 0,12230746 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04215427 0,12216238 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,04215427 0,12201764 ! prostate gland development GO:0030850 14 7 0,000 0,04215427 0,12187324 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,04215427 0,12172918 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04215427 0,12158546 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04215427 0,12144208 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,04215427 0,12129904 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04215427 0,12115634 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,04215427 0,12101397 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,04215427 0,12087193 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04215427 0,12073023 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,04215427 0,12058886 ! glycolipid transport GO:0046836 11 7 0,000 0,04215427 0,12044782 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04215427 0,12030711 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,04215427 0,12016673 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04215427 0,12002667 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04215427 0,11988694 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,04215427 0,11974754 ! pericardium development GO:0060039 16 7 0,000 0,04215427 0,11960846 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,04215427 0,1194697 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,04215427 0,11933127 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,04215427 0,11919315 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,04215427 0,11905536 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04215427 0,11891788 ! lipoprotein transport GO:0042953 14 7 0,000 0,04215427 0,11878072 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,04215427 0,11864388 ! rhythmic behavior GO:0007622 17 7 0,000 0,04215427 0,11850735 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,04215427 0,11837113 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,04215427 0,11823523 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,04215427 0,11809964 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,04215427 0,11796436 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04215427 0,11782939 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,04215427 0,11769473 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04215427 0,11756037 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,04215427 0,11742632 ! mechanosensory behavior GO:0007638 16 7 0,000 0,04215427 0,11729258 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,04215427 0,11715914 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,04215427 0,11702601 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,04215427 0,11689317 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,04215427 0,11676064 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04215427 0,11662841 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04215427 0,11649648 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,04215427 0,11636484 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,04215427 0,1162335 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04215427 0,11610246 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,04215427 0,11597172 ! adrenal gland development GO:0030325 17 7 0,000 0,04215427 0,11584127 ! cysteine metabolic process GO:0006534 13 7 0,000 0,04215427 0,11571111 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,04215427 0,11558124 ! ovulation GO:0030728 10 7 0,000 0,04215427 0,11545166 ! adenohypophysis development GO:0021984 11 7 0,000 0,04215427 0,11532238 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,04215427 0,11519338 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,04215427 0,11506468 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,04215427 0,11493626 ! microtubule nucleation GO:0007020 21 7 0,000 0,04215427 0,11480812 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04215427 0,11468027 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,04215427 0,11455271 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04215427 0,11442543 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,04215427 0,11429843 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,04215427 0,11417171 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04215427 0,11404528 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,04215427 0,11391912 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,04215427 0,11379324 ! galactose metabolic process GO:0006012 13 7 0,000 0,04215427 0,11366764 ! vesicle fusion GO:0006906 20 7 0,000 0,04215427 0,11354232 ! response to dietary excess GO:0002021 8 7 0,000 0,04215427 0,11341727 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04215427 0,1132925 ! intracellular pH reduction GO:0051452 13 7 0,000 0,04215427 0,11316801 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04215427 0,11304378 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,04215427 0,11291983 ! organ growth GO:0035265 15 7 0,000 0,04215427 0,11279615 ! nucleoside transport GO:0015858 11 7 0,000 0,04215427 0,11267274 ! nucleoside salvage GO:0043174 11 7 0,000 0,04215427 0,1125496 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,04215427 0,11242673 ! male sex determination GO:0030238 15 7 0,000 0,04215427 0,11230413 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,04215427 0,11218179 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,04215427 0,11205972 ! parturition GO:0007567 16 7 0,000 0,04215427 0,11193792 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,04215427 0,11181638 ! rRNA modification GO:0000154 14 7 0,000 0,04215427 0,1116951 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,04215427 0,11157409 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,04215427 0,11145334 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,04215427 0,11133285 ! monocyte differentiation GO:0030224 16 7 0,000 0,04215427 0,11121262 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,04215427 0,11109265 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04215427 0,11097294 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,04215427 0,11085348 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,04215427 0,11073428 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,04215427 0,11061534 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04215427 0,11049666 ! fibrinolysis GO:0042730 11 7 0,000 0,04215427 0,11037823 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,04215427 0,11026005 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,04215427 0,11014212 ! eating behavior GO:0042755 8 7 0,000 0,04215427 0,11002445 ! B cell lineage commitment GO:0002326 21 7 0,000 0,04215427 0,10990703 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04215427 0,10978986 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,04215427 0,10967293 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,04215427 0,10955626 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04215427 0,10943984 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,04215427 0,10932366 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04215427 0,10920773 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,04215427 0,10909204 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,04215427 0,1089766 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,04215427 0,1088614 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04215427 0,10874645 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,04215427 0,10863173 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04215427 0,10851727 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04215427 0,10840304 ! histone ubiquitination GO:0016574 9 7 0,000 0,04215427 0,10828905 ! regulation of meiosis GO:0040020 12 7 0,000 0,04215427 0,1081753 GO:0051445|regulation of meiotic cell cycle, ! T cell lineage commitment GO:0002360 16 7 0,000 0,04215427 0,10806179 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,04215427 0,10794852 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04215427 0,10783548 ! membrane to membrane docking GO:0022614 14 7 0,000 0,04215427 0,10772268 ! transcription termination GO:0006353 14 7 0,000 0,04215427 0,10761012 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04215427 0,10749779 ! anaphase GO:0051322 18 7 0,000 0,04215427 0,1073857 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,04215427 0,10727384 ! axonal fasciculation GO:0007413 19 7 0,000 0,04215427 0,10716221 ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,04215427 0,10705082 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,04215427 0,10693965 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,04215427 0,10682872 ! diuresis GO:0030146 12 7 0,000 0,04215427 0,10671802 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04215427 0,10660754 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04215427 0,1064973 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04215427 0,10638728 ! antibiotic transport GO:0042891 9 7 0,000 0,04215427 0,10627749 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04215427 0,10616792 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,04215427 0,10605858 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,04215427 0,10594947 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,04215427 0,10584058 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,04215427 0,10573191 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,04215427 0,10562347 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,04215427 0,10551525 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04215427 0,10540725 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04215427 0,10529947 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,04215427 0,10519191 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,04215427 0,10508458 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,04215427 0,10497746 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,04215427 0,10487055 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,04215427 0,10476387 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,04215427 0,1046574 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,04215427 0,10455115 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,04215427 0,10444512 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,04215427 0,1043393 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04215427 0,10423369 ! muscle adaptation GO:0043500 13 7 0,000 0,04215427 0,1041283 ! embryonic heart tube development GO:0035050 14 7 0,000 0,04215427 0,10402312 ! retina homeostasis GO:0001895 12 7 0,000 0,04215427 0,10391815 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,04215427 0,10381339 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,04215427 0,10370885 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,04215427 0,10360451 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,04215427 0,10350039 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,04350227 0,10670287 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,04350227 0,10659584 GO:0010863|positive regulation of phospholipase C activity, ! embryonic skeletal system development GO:0048706 101 54 1,000 0,04350227 0,10648903 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 1,000 0,04350227 0,10638244 ! covalent chromatin modification GO:0016569 115 54 1,000 0,04350227 0,10627605 ! regulation of cell shape GO:0008360 142 54 1,000 0,04350227 0,10616988 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 0,04350227 0,10606393 ! regulation of multicellular organism growth GO:0040014 90 55 1,000 0,04496571 0,10952267 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,04496571 0,10941358 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,04644718 0,11290593 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,0479464 0,11643445 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,0479464 0,11631883 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,04803013 0,11640636 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,04803013 0,11629099 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,04803013 0,11617585 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,04803013 0,11606094 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,04803013 0,11594625 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04803013 0,11583179 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04803013 0,11571756 ! male meiosis GO:0007140 9 8 0,000 0,04803013 0,11560355 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,04803013 0,11548977 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,04803013 0,11537621 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,04803013 0,11526287 ! meiotic prophase I GO:0007128 14 8 0,000 0,04803013 0,11514976 ! response to zinc ion GO:0010043 12 8 0,000 0,04803013 0,11503687 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,04803013 0,1149242 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04803013 0,11481175 ! oligopeptide transport GO:0006857 16 8 0,000 0,04803013 0,11469952 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,04803013 0,11458751 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,04803013 0,11447571 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,04803013 0,11436414 ! signal peptide processing GO:0006465 12 8 0,000 0,04803013 0,11425278 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,04803013 0,11414164 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,04803013 0,11403072 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04803013 0,11392001 ! succinate metabolic process GO:0006105 17 8 0,000 0,04803013 0,11380951 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,04803013 0,11369923 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,04803013 0,11358916 ! estrogen metabolic process GO:0008210 17 8 0,000 0,04803013 0,11347931 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,04803013 0,11336967 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,04803013 0,11326024 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04803013 0,11315102 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04803013 0,11304201 ! reflex GO:0060004 17 8 0,000 0,04803013 0,11293321 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04803013 0,11282462 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,04803013 0,11271624 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04803013 0,11260807 ! pigment granule organization GO:0048753 17 8 0,000 0,04803013 0,1125001 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04803013 0,11239234 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,04803013 0,11228479 ! histidine catabolic process GO:0006548 10 8 0,000 0,04803013 0,11217744 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04803013 0,1120703 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,04803013 0,11196336 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,04803013 0,11185663 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,04803013 0,1117501 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,04803013 0,11164377 ! melanin metabolic process GO:0006582 17 8 0,000 0,04803013 0,11153765 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,04803013 0,11143172 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,04803013 0,111326 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,04803013 0,11122048 ! macrophage activation GO:0042116 13 8 0,000 0,04803013 0,11111516 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04803013 0,11101003 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,04803013 0,11090511 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04803013 0,11080038 ! purine salvage GO:0043101 12 8 0,000 0,04803013 0,11069585 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,04803013 0,11059152 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,04803013 0,11048739 ! osteoblast development GO:0002076 17 8 0,000 0,04803013 0,11038345 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,04803013 0,1102797 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,04803013 0,11017616 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,04803013 0,1100728 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04803013 0,10996964 ! response to UV-B GO:0010224 17 8 0,000 0,04803013 0,10986667 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,04803013 0,1097639 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04803013 0,10966131 ! intermediate filament organization GO:0045109 12 8 0,000 0,04803013 0,10955892 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,04803013 0,10945672 ! cellular extravasation GO:0045123 13 8 0,000 0,04803013 0,10935471 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,04803013 0,10925289 ! response to antibiotic GO:0046677 11 8 0,000 0,04803013 0,10915126 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,04803013 0,10904982 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,04803013 0,10894857 ! DNA topological change GO:0006265 12 8 0,000 0,04803013 0,1088475 ! response to tropane GO:0014073 15 8 0,000 0,04803013 0,10874662 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,04803013 0,10864593 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,04803013 0,10854543 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04803013 0,10844511 ! mast cell activation GO:0045576 14 8 0,000 0,04803013 0,10834497 ! multicellular organismal aging GO:0010259 20 8 0,000 0,04803013 0,10824502 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,04803013 0,10814526 ! gas homeostasis GO:0033483 14 8 0,000 0,04803013 0,10804568 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,04803013 0,10794628 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,04803013 0,10784706 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,04803013 0,10774803 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04803013 0,10764918 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04803013 0,10755051 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,04803013 0,10745202 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04803013 0,10735371 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,04803013 0,10725558 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,04803013 0,10715763 ! intracellular lipid transport GO:0032365 16 8 0,000 0,04803013 0,10705986 ! response to tumor cell GO:0002347 16 8 0,000 0,04803013 0,10696227 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04803013 0,10686485 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,04803013 0,10676761 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,04803013 0,10667055 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04803013 0,10657367 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,04803013 0,10647696 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,04803013 0,10638042 ! hormone catabolic process GO:0042447 17 8 0,000 0,04803013 0,10628406 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,04803013 0,10618788 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,04803013 0,10609187 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,04803013 0,10599603 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,04803013 0,10590037 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04803013 0,10580487 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,04803013 0,10570956 ! adult feeding behavior GO:0008343 10 8 0,000 0,04803013 0,10561441 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,04803013 0,10551943 ! ATP catabolic process GO:0006200 11 8 0,000 0,04803013 0,10542462 ! blastocyst growth GO:0001832 19 8 0,000 0,04803013 0,10532999 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04803013 0,10523552 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04803013 0,10514122 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,04803013 0,1050471 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04803013 0,10495314 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,04803013 0,10485934 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,04803013 0,10476572 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,04803013 0,10467226 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,04803013 0,10457897 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,04803013 0,10448585 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,04803013 0,10439289 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04803013 0,10430009 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,04803013 0,10420747 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,04803013 0,104115 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04803013 0,1040227 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,04803013 0,10393056 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,04803013 0,10383859 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,04803013 0,10374678 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,04803013 0,10365513 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,04803013 0,10356364 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,04946311 0,10655941 ! aging GO:0007568 112 58 1,000 0,04946311 0,10646552 ! gastrulation GO:0007369 122 58 1,000 0,04946311 0,1063718 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,04946311 0,10627825 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,04946311 0,10618486 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,04946311 0,10609163 ! lipid modification GO:0030258 112 60 1,000 0,0525479 0,11260922 ! kidney development GO:0001822 133 60 1,000 0,0525479 0,11251053 ! axon extension GO:0048675 16 9 0,000 0,05387011 0,11524052 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,05387011 0,11513969 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,05387011 0,11503905 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,05387011 0,11493858 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05387011 0,11483828 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,05387011 0,11473816 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,05387011 0,11463821 ! reproductive behavior GO:0019098 22 9 0,000 0,05387011 0,11453844 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05387011 0,11443884 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,05387011 0,11433942 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,05387011 0,11424017 ! UTP metabolic process GO:0046051 10 9 0,000 0,05387011 0,11414108 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,05387011 0,11404218 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,05387011 0,11394344 ! artery development GO:0060840 25 9 0,000 0,05387011 0,11384487 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,05387011 0,11374647 ! regulation of glycolysis GO:0006110 20 9 0,000 0,05387011 0,11364825 ! equilibrioception GO:0050957 20 9 0,000 0,05387011 0,11355019 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,05387011 0,1134523 ! chemosensory behavior GO:0007635 21 9 0,000 0,05387011 0,11335458 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,05387011 0,11325703 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05387011 0,11315965 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,05387011 0,11306243 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,05387011 0,11296538 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,05387011 0,1128685 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,05387011 0,11277178 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05387011 0,11267523 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05387011 0,11257885 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,05387011 0,11248262 ! protein targeting to ER GO:0045047 25 9 0,000 0,05387011 0,11238657 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,05387011 0,11229067 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,05387011 0,11219495 ! T cell selection GO:0045058 27 9 0,000 0,05387011 0,11209938 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,05387011 0,11200397 ! glycine catabolic process GO:0006546 15 9 0,000 0,05387011 0,11190873 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,05387011 0,11181365 ! endosome organization GO:0007032 20 9 0,000 0,05387011 0,11171874 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05387011 0,11162398 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,05387011 0,11152938 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05387011 0,11143495 ! mannose metabolic process GO:0006013 13 9 0,000 0,05387011 0,11134067 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,05387011 0,11124655 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,05387011 0,11115259 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,05387011 0,11105879 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,05387011 0,11096515 ! receptor clustering GO:0043113 20 9 0,000 0,05387011 0,11087167 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,05387011 0,11077834 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05387011 0,11068517 ! retinol metabolic process GO:0042572 20 9 0,000 0,05387011 0,11059216 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,05387011 0,1104993 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,05387011 0,1104066 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,05387011 0,11031406 ! macrophage differentiation GO:0030225 15 9 0,000 0,05387011 0,11022167 ! oligodendrocyte development GO:0014003 11 9 0,000 0,05387011 0,11012943 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,05387011 0,11003735 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05387011 0,10994542 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,05387011 0,10985365 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05387011 0,10976203 ! response to amine stimulus GO:0014075 13 9 0,000 0,05387011 0,10967056 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05387011 0,10957924 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,05387011 0,10948808 ! erythrocyte development GO:0048821 17 9 0,000 0,05387011 0,10939707 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05387011 0,1093062 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,05387011 0,10921549 ! renal water homeostasis GO:0003091 15 9 0,000 0,05387011 0,10912493 ! postreplication repair GO:0006301 25 9 0,000 0,05387011 0,10903452 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,05387011 0,10894426 ! icosanoid secretion GO:0032309 15 9 0,000 0,05387011 0,10885415 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05387011 0,10876419 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,05387011 0,10867438 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,05387011 0,10858471 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,05387011 0,10849519 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05387011 0,10840582 ! sterol catabolic process GO:0016127 14 9 0,000 0,05387011 0,1083166 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05387011 0,10822753 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,05387011 0,1081386 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,05387011 0,10804981 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,05387011 0,10796117 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,05387011 0,10787268 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,05387011 0,10778433 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,05387011 0,10769613 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,05387011 0,10760807 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05387011 0,10752016 ! purine base metabolic process GO:0006144 25 9 0,000 0,05387011 0,10743238 ! pigment granule transport GO:0051904 17 9 0,000 0,05387011 0,10734476 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,05387011 0,10725727 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,05387011 0,10716993 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05387011 0,10708273 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,05387011 0,10699567 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,05387011 0,10690875 ! mitochondrion localization GO:0051646 18 9 0,000 0,05387011 0,10682197 ! positive regulation of secretion GO:0051047 110 61 1,000 0,05411545 0,10722145 ! mesoderm development GO:0007498 128 63 1,000 0,05729957 0,1134383 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,05967442 0,11804422 ! regulation of developmental growth GO:0048638 16 10 0,000 0,05967442 0,11794871 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,05967442 0,11785336 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05967442 0,11775817 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,05967442 0,11766312 ! associative learning GO:0008306 21 10 0,000 0,05967442 0,11756823 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05967442 0,1174735 ! phosphate transport GO:0006817 24 10 0,000 0,05967442 0,11737891 ! cell volume homeostasis GO:0006884 17 10 0,000 0,05967442 0,11728448 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,05967442 0,1171902 ! CTP metabolic process GO:0046036 11 10 0,000 0,05967442 0,11709607 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,05967442 0,1170021 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,05967442 0,11690827 ! GTP metabolic process GO:0046039 11 10 0,000 0,05967442 0,11681459 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,05967442 0,11672107 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,05967442 0,11662769 ! social behavior GO:0035176 29 10 0,000 0,05967442 0,11653446 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,05967442 0,11644138 GO:0048200|Golgi transport vesicle coating, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,05967442 0,11634845 ! androgen metabolic process GO:0008209 17 10 0,000 0,05967442 0,11625567 ! phospholipid efflux GO:0033700 19 10 0,000 0,05967442 0,11616304 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05967442 0,11607055 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,05967442 0,11597821 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,05967442 0,11588602 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,05967442 0,11579397 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05967442 0,11570207 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,05967442 0,11561032 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,05967442 0,11551871 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,05967442 0,11542725 ! endoderm development GO:0007492 18 10 0,000 0,05967442 0,11533593 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,05967442 0,11524475 ! arginine catabolic process GO:0006527 17 10 0,000 0,05967442 0,11515372 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05967442 0,11506283 ! proline metabolic process GO:0006560 13 10 0,000 0,05967442 0,11497209 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05967442 0,11488149 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,05967442 0,11479103 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,05967442 0,11470072 ! V(D)J recombination GO:0033151 34 10 0,000 0,05967442 0,11461054 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,05967442 0,11452051 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,05967442 0,11443062 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,05967442 0,11434087 ! B cell proliferation GO:0042100 19 10 0,000 0,05967442 0,11425126 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,05967442 0,11416179 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,05967442 0,11407247 ! multicellular organism growth GO:0035264 19 10 0,000 0,05967442 0,11398328 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,05967442 0,11389423 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,05967442 0,11380532 ! ruffle organization GO:0031529 17 10 0,000 0,05967442 0,11371655 ! epithelial cell development GO:0002064 21 10 0,000 0,05967442 0,11362791 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,05967442 0,11353942 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05967442 0,11345106 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,05967442 0,11336284 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,05967442 0,11327476 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,05967442 0,11318681 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,05967442 0,113099 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,05967442 0,11301133 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05967442 0,11292379 ! protein heterooligomerization GO:0051291 17 10 0,000 0,05967442 0,11283639 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05967442 0,11274912 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05967442 0,11266199 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,05967442 0,11257499 ! segment specification GO:0007379 15 10 0,000 0,05967442 0,11248813 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,05967442 0,1124014 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,05967442 0,1123148 ! blastoderm segmentation GO:0007350 19 10 0,000 0,05967442 0,11222834 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,05967442 0,11214201 ! response to dsRNA GO:0043331 23 10 0,000 0,05967442 0,11205581 ! DNA ligation GO:0006266 18 10 0,000 0,05967442 0,11196975 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,05967442 0,11188381 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05967442 0,11179801 ! melanosome localization GO:0032400 16 10 0,000 0,05967442 0,11171235 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,05967442 0,11162681 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,05967442 0,1115414 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05967442 0,11145612 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,05967442 0,11137098 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,05967442 0,11128596 ! protein sumoylation GO:0016925 17 10 0,000 0,05967442 0,11120108 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,05967442 0,11111632 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05967442 0,11103169 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05967442 0,11094719 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05967442 0,11086282 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,05967442 0,11077858 ! salivary gland development GO:0007431 28 10 0,000 0,05967442 0,11069447 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,05967442 0,11061048 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,05967442 0,11052662 ! midbrain development GO:0030901 14 10 0,000 0,05967442 0,11044289 ! musculoskeletal movement GO:0050881 16 10 0,000 0,05967442 0,11035928 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,05967442 0,1102758 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,05967442 0,11019245 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,05967442 0,11010922 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,05967442 0,11002612 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,05967442 0,10994315 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05967442 0,10986029 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05967442 0,10977757 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,05967442 0,10969497 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,05967442 0,10961249 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05967442 0,10953014 ! blastocyst formation GO:0001825 18 10 0,000 0,05967442 0,10944791 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,05967442 0,1093658 ! cerebellar cortex development GO:0021695 16 10 0,000 0,05967442 0,10928382 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,05967442 0,10920196 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,05967442 0,10912022 ! response to nicotine GO:0035094 20 10 0,000 0,05967442 0,1090386 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,05967442 0,10895711 ! multicellular organism reproduction GO:0032504 123 65 1,000 0,06054734 0,11046838 GO:0048609|reproductive process in a multicellular organism, ! ear development GO:0043583 114 66 1,000 0,06219446 0,11338886 ! regulation of cytokine biosynthetic process GO:0042035 108 66 1,000 0,06219446 0,1133043 ! gonad development GO:0008406 115 66 1,000 0,06219446 0,11321987 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,06385674 0,11615935 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 1,000 0,06385674 0,11607293 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,06544329 0,11886837 ! respiratory burst GO:0045730 17 11 0,000 0,06544329 0,11878006 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,06544329 0,11869188 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,06544329 0,11860383 ! thyroid gland development GO:0030878 26 11 0,000 0,06544329 0,11851591 ! synapsis GO:0007129 14 11 0,000 0,06544329 0,11842812 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,06544329 0,11834046 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,06544329 0,11825293 ! response to pain GO:0048265 27 11 0,000 0,06544329 0,11816553 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,06544329 0,11807825 ! bone resorption GO:0045453 16 11 0,000 0,06544329 0,11799111 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,06544329 0,1179041 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06544329 0,11781721 ! melanocyte differentiation GO:0030318 20 11 0,000 0,06544329 0,11773045 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,06544329 0,11764382 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,06544329 0,11755732 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,06544329 0,11747095 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,06544329 0,1173847 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,06544329 0,11729857 ! UV protection GO:0009650 20 11 0,000 0,06544329 0,11721258 ! adult heart development GO:0007512 16 11 0,000 0,06544329 0,11712671 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,06544329 0,11704096 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06544329 0,11695535 ! macroautophagy GO:0016236 19 11 0,000 0,06544329 0,11686985 ! temperature homeostasis GO:0001659 18 11 0,000 0,06544329 0,11678448 ! behavioral fear response GO:0001662 27 11 0,000 0,06544329 0,11669924 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,06544329 0,11661412 ! negative regulation of ossification GO:0030279 27 11 0,000 0,06544329 0,11652912 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,06544329 0,11644425 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,06544329 0,1163595 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,06544329 0,11627488 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,06544329 0,11619038 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,06544329 0,116106 ! regulation of organ growth GO:0046620 14 11 0,000 0,06544329 0,11602174 ! pigment granule localization GO:0051875 20 11 0,000 0,06544329 0,1159376 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,06544329 0,11585359 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,06544329 0,1157697 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06544329 0,11568593 ! embryonic axis specification GO:0000578 19 11 0,000 0,06544329 0,11560228 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,06544329 0,11551875 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06544329 0,11543535 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,06544329 0,11535206 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,06544329 0,11526889 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,06544329 0,11518585 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,06544329 0,11510292 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,06544329 0,11502011 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,06544329 0,11493742 ! prophase GO:0051324 17 11 0,000 0,06544329 0,11485485 ! neuroblast proliferation GO:0007405 25 11 0,000 0,06544329 0,1147724 ! regulation of isotype switching GO:0045191 24 11 0,000 0,06544329 0,11469007 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,06544329 0,11460785 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,06544329 0,11452576 ! apical protein localization GO:0045176 18 11 0,000 0,06544329 0,11444378 ! acid secretion GO:0046717 20 11 0,000 0,06544329 0,11436191 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06544329 0,11428017 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,06544329 0,11419854 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,06544329 0,11411703 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,06544329 0,11403563 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,06544329 0,11395435 ! cholesterol efflux GO:0033344 21 11 0,000 0,06544329 0,11387319 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06544329 0,11379214 ! oocyte development GO:0048599 20 11 0,000 0,06544329 0,11371121 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,06544329 0,11363039 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,06544329 0,11354969 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,06544329 0,1134691 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,06544329 0,11338862 ! activation of innate immune response GO:0002218 16 11 0,000 0,06544329 0,11330826 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,06544329 0,11322801 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,06544329 0,11314788 ! lysogeny GO:0030069 22 11 0,000 0,06544329 0,11306786 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06544329 0,11298796 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,06544329 0,11290816 ! sequestering of metal ion GO:0051238 15 11 0,000 0,06544329 0,11282848 ! regulation of embryonic development GO:0045995 35 11 0,000 0,06544329 0,11274891 ! nucleus localization GO:0051647 22 11 0,000 0,06544329 0,11266946 ! regulation of cellular response to stress GO:0080135 142 68 1,000 0,06553393 0,11274604 ! detection of external stimulus GO:0009581 102 68 1,000 0,06553393 0,1126667 ! regulation of lipase activity GO:0060191 137 68 1,000 0,06553393 0,11258747 ! adaptive immune response GO:0002250 126 68 1,000 0,06553393 0,11250835 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! urogenital system development GO:0001655 149 69 1,000 0,06722578 0,11533188 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,06722578 0,11525094 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,07117693 0,12193915 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,07117693 0,1218537 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,07117693 0,12176837 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,07117693 0,12168316 ! virus-host interaction GO:0019048 30 12 0,000 0,07117693 0,12159807 ! mating GO:0007618 17 12 0,000 0,07117693 0,12151309 ! protein complex disassembly GO:0043241 28 12 0,000 0,07117693 0,12142824 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,07117693 0,1213435 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,07117693 0,12125888 ! hippocampus development GO:0021766 29 12 0,000 0,07117693 0,12117438 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,07117693 0,12109 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,07117693 0,12100573 ! T cell proliferation GO:0042098 32 12 0,000 0,07117693 0,12092158 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,07117693 0,12083755 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,07117693 0,12075364 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,07117693 0,12066984 ! drug transport GO:0015893 16 12 0,000 0,07117693 0,12058615 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,07117693 0,12050259 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,07117693 0,12041914 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,07117693 0,1203358 ! polyamine metabolic process GO:0006595 18 12 0,000 0,07117693 0,12025258 ! mitotic spindle organization GO:0007052 23 12 0,000 0,07117693 0,12016948 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,07117693 0,12008649 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,07117693 0,12000361 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 21 12 0,000 0,07117693 0,11992085 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,07117693 0,1198382 ! entry into host cell GO:0030260 34 12 0,000 0,07117693 0,11975567 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07117693 0,11967325 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,07117693 0,11959095 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,07117693 0,11950875 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07117693 0,11942667 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,07117693 0,1193447 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,07117693 0,11926285 ! snRNA metabolic process GO:0016073 30 12 0,000 0,07117693 0,11918111 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,07117693 0,11909948 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,07117693 0,11901796 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,07117693 0,11893655 ! fucose catabolic process GO:0019317 25 12 0,000 0,07117693 0,11885525 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,07117693 0,11877407 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,07117693 0,11869299 ! autonomic nervous system development GO:0048483 24 12 0,000 0,07117693 0,11861203 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,07117693 0,11853118 ! zymogen activation GO:0031638 18 12 0,000 0,07117693 0,11845043 ! T cell homeostasis GO:0043029 28 12 0,000 0,07117693 0,1183698 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,07117693 0,11828928 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,07117693 0,11820886 ! oocyte differentiation GO:0009994 21 12 0,000 0,07117693 0,11812856 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,07117693 0,11804836 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,07117693 0,11796827 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,07117693 0,11788829 ! defense response to fungus GO:0050832 15 12 0,000 0,07117693 0,11780842 ! embryonic placenta development GO:0001892 21 12 0,000 0,07117693 0,11772866 ! lamellipodium assembly GO:0030032 24 12 0,000 0,07117693 0,11764901 ! response to cold GO:0009409 17 12 0,000 0,07117693 0,11756946 ! establishment of cell polarity GO:0030010 21 12 0,000 0,07117693 0,11749002 ! regulation of synapse organization GO:0050807 18 12 0,000 0,07117693 0,11741069 ! actin filament organization GO:0007015 167 72 1,000 0,07238697 0,11932615 ! regulation of MAPKKK cascade GO:0043408 157 72 1,000 0,07238697 0,11924569 ! humoral immune response GO:0006959 115 73 1,000 0,07413511 0,12204318 ! regulation of immune effector process GO:0002697 156 73 1,000 0,07413511 0,12196099 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,07687555 0,12638423 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07687555 0,12629924 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,07687555 0,12621436 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07687555 0,1261296 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07687555 0,12604494 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,07687555 0,12596041 ! peroxisomal transport GO:0043574 28 13 0,000 0,07687555 0,12587598 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,07687555 0,12579167 ! cartilage condensation GO:0001502 22 13 0,000 0,07687555 0,12570748 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,07687555 0,12562339 ! organelle fusion GO:0048284 36 13 0,000 0,07687555 0,12553942 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,07687555 0,12545556 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,07687555 0,12537181 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,07687555 0,12528817 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,07687555 0,12520465 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,07687555 0,12512123 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,07687555 0,12503793 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,07687555 0,12495474 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07687555 0,12487165 ! methionine metabolic process GO:0006555 31 13 0,000 0,07687555 0,12478868 ! plasma membrane organization GO:0007009 27 13 0,000 0,07687555 0,12470582 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,07687555 0,12462307 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,07687555 0,12454043 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,07687555 0,1244579 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,07687555 0,12437548 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,07687555 0,12429316 ! cytokine metabolic process GO:0042107 24 13 0,000 0,07687555 0,12421096 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,07687555 0,12412886 ! exocrine system development GO:0035272 34 13 0,000 0,07687555 0,12404687 ! asymmetric protein localization GO:0008105 24 13 0,000 0,07687555 0,123965 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,07687555 0,12388322 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,07687555 0,12380156 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,07687555 0,12372001 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,07687555 0,12363856 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,07687555 0,12355722 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,07687555 0,12347598 ! protein homotetramerization GO:0051289 24 13 0,000 0,07687555 0,12339485 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,07687555 0,12331383 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,07687555 0,12323292 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,07687555 0,12315211 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,07687555 0,12307141 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,07687555 0,12299081 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07687555 0,12291032 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,07687555 0,12282993 ! histone methylation GO:0016571 29 13 0,000 0,07687555 0,12274965 ! chromatin silencing GO:0006342 29 13 0,000 0,07687555 0,12266948 ! gland morphogenesis GO:0022612 31 13 0,000 0,07687555 0,1225894 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,07687555 0,12250944 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07687555 0,12242957 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,07687555 0,12234982 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,07687555 0,12227016 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,07687555 0,12219061 ! spleen development GO:0048536 24 13 0,000 0,07687555 0,12211116 ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,07687555 0,12203182 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,07687555 0,12195258 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,07687555 0,12187344 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,07687555 0,1217944 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,07687555 0,12171547 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,07687555 0,12163664 ! insulin secretion GO:0030073 24 13 0,000 0,07687555 0,12155791 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,07687555 0,12147928 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,07687555 0,12140075 ! acrosome reaction GO:0007340 19 13 0,000 0,07687555 0,12132233 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,07687555 0,12124401 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,07687555 0,12116579 ! transition metal ion transport GO:0000041 143 75 1,000 0,07767163 0,12234158 ! reproductive structure development GO:0048608 131 75 1,000 0,07767163 0,12226275 ! rhythmic process GO:0048511 142 75 1,000 0,07767163 0,12218403 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,07945955 0,12491614 ! learning or memory GO:0007611 161 76 1,000 0,07945955 0,1248358 ! regulation of blood pressure GO:0008217 134 76 1,000 0,07945955 0,12475557 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,08126027 0,12750086 ! rRNA transcription GO:0009303 28 14 0,000 0,08253937 0,1294247 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,08253937 0,12934168 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,08253937 0,12925877 ! water transport GO:0006833 21 14 0,000 0,08253937 0,12917596 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,08253937 0,12909326 ! non-recombinational repair GO:0000726 29 14 0,000 0,08253937 0,12901067 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,08253937 0,12892818 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,08253937 0,1288458 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,08253937 0,12876352 ! RNA polyadenylation GO:0043631 32 14 0,000 0,08253937 0,12868135 ! lipid localization GO:0010876 32 14 0,000 0,08253937 0,12859928 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,08253937 0,12851732 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,08253937 0,12843546 ! regulated secretory pathway GO:0045055 24 14 0,000 0,08253937 0,12835371 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,08253937 0,12827206 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,08253937 0,12819051 ! arginine metabolic process GO:0006525 21 14 0,000 0,08253937 0,12810907 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,08253937 0,12802773 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,08253937 0,12794649 ! regulation of heart rate GO:0002027 25 14 0,000 0,08253937 0,12786536 ! fear response GO:0042596 34 14 0,000 0,08253937 0,12778433 ! organic alcohol transport GO:0015850 29 14 0,000 0,08253937 0,1277034 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,08253937 0,12762258 ! embryo implantation GO:0007566 30 14 0,000 0,08253937 0,12754186 ! neutral amino acid transport GO:0015804 28 14 0,000 0,08253937 0,12746124 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,08253937 0,12738072 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,08253937 0,1273003 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,08253937 0,12721998 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,08253937 0,12713977 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,08253937 0,12705966 ! regulation of cellular pH GO:0030641 27 14 0,000 0,08253937 0,12697964 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,08253937 0,12689973 ! ribosome assembly GO:0042255 18 14 0,000 0,08253937 0,12681992 ! cerebellum development GO:0021549 23 14 0,000 0,08253937 0,12674021 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,08253937 0,1266606 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,08253937 0,12658109 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,08253937 0,12650168 ! response to gamma radiation GO:0010332 30 14 0,000 0,08253937 0,12642237 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,08253937 0,12634316 ! NADP metabolic process GO:0006739 24 14 0,000 0,08253937 0,12626404 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,08253937 0,12618503 ! oxygen transport GO:0015671 22 14 0,000 0,08253937 0,12610611 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08253937 0,1260273 ! male genitalia development GO:0030539 26 14 0,000 0,08253937 0,12594858 ! regulation of axon extension GO:0030516 43 14 0,000 0,08253937 0,12586996 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,08253937 0,12579144 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,08253937 0,12571302 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,08307358 0,12644782 ! blood coagulation GO:0007596 151 79 1,000 0,08489925 0,12914624 GO:0050817|coagulation, ! regulation of synaptic transmission GO:0050804 159 79 1,000 0,08489925 0,12906587 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,08673706 0,13177776 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,08816859 0,13386941 ! lactation GO:0007595 30 15 0,000 0,08816859 0,13378626 ! reproductive cellular process GO:0048610 22 15 0,000 0,08816859 0,13370321 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08816859 0,13362027 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,08816859 0,13353743 ! superoxide anion generation GO:0042554 22 15 0,000 0,08816859 0,13345469 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,08816859 0,13337206 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,08816859 0,13328953 ! copper ion transport GO:0006825 22 15 0,000 0,08816859 0,1332071 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,08816859 0,13312477 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,08816859 0,13304254 ! sulfate transport GO:0008272 27 15 0,000 0,08816859 0,13296042 ! response to cAMP GO:0051591 25 15 0,000 0,08816859 0,13287839 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,08816859 0,13279647 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,08816859 0,13271465 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,08816859 0,13263293 ! vesicle coating GO:0006901 38 15 0,000 0,08816859 0,13255131 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,08816859 0,13246979 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,08816859 0,13238837 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,08816859 0,13230705 ! regulation of exocytosis GO:0017157 26 15 0,000 0,08816859 0,13222583 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,08816859 0,13214471 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,08816859 0,13206369 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,08816859 0,13198277 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,08816859 0,13190195 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,08816859 0,13182122 ! regulation of vasodilation GO:0042312 27 15 0,000 0,08816859 0,1317406 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,08816859 0,13166007 ! histone deacetylation GO:0016575 24 15 0,000 0,08816859 0,13157964 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,08816859 0,13149931 ! water homeostasis GO:0030104 28 15 0,000 0,08816859 0,13141908 ! cofactor transport GO:0051181 30 15 0,000 0,08816859 0,13133895 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08816859 0,13125891 ! muscle maintenance GO:0046716 26 15 0,000 0,08816859 0,13117897 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,08816859 0,13109913 ! intestinal absorption GO:0050892 31 15 0,000 0,08816859 0,13101939 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08816859 0,13093974 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,08816859 0,13086019 ! heme biosynthetic process GO:0006783 33 15 0,000 0,08816859 0,13078074 ! cell killing GO:0001906 32 15 0,000 0,08816859 0,13070138 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,08816859 0,13062212 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,08816859 0,13054296 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,08816859 0,13046389 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,08816859 0,13038491 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,08816859 0,13030604 ! actin filament polymerization GO:0030041 27 15 0,000 0,08816859 0,13022725 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,08816859 0,13014857 ! meiosis GO:0007126 143 81 1,000 0,0885868 0,13068693 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 1,000 0,0885868 0,13060806 ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,0885868 0,13052928 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,09044825 0,13319173 ! meiotic cell cycle GO:0051321 144 82 1,000 0,09044825 0,1331115 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,09232121 0,1357861 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,09376344 0,13782436 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,09376344 0,13774148 ! positive regulation of cell size GO:0045793 29 16 0,000 0,09376344 0,1376587 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,09376344 0,13757603 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,09376344 0,13749345 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,09376344 0,13741097 ! bone remodeling GO:0046849 28 16 0,000 0,09376344 0,13732859 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,09376344 0,1372463 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,09376344 0,13716412 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,09376344 0,13708204 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,09376344 0,13700005 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,09376344 0,13691816 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,09376344 0,13683637 ! startle response GO:0001964 28 16 0,000 0,09376344 0,13675468 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,09376344 0,13667308 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,09376344 0,13659158 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,09376344 0,13651018 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,09376344 0,13642888 ! protein polyubiquitination GO:0000209 41 16 0,000 0,09376344 0,13634767 ! glutamate metabolic process GO:0006536 25 16 0,000 0,09376344 0,13626656 ! response to osmotic stress GO:0006970 27 16 0,000 0,09376344 0,13618554 ! lysosomal transport GO:0007041 31 16 0,000 0,09376344 0,13610462 ! fructose metabolic process GO:0006000 25 16 0,000 0,09376344 0,1360238 ! L-amino acid transport GO:0015807 33 16 0,000 0,09376344 0,13594308 ! stem cell development GO:0048864 46 16 0,000 0,09376344 0,13586245 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,09376344 0,13578191 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,09376344 0,13570147 ! intermediate filament-based process GO:0045103 36 16 0,000 0,09376344 0,13562113 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,09376344 0,13554088 ! negative regulation of immune response GO:0050777 38 16 0,000 0,09376344 0,13546072 ! axon cargo transport GO:0008088 46 16 0,000 0,09376344 0,13538066 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,09376344 0,1353007 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,09376344 0,13522083 ! DNA replication initiation GO:0006270 28 16 0,000 0,09376344 0,13514105 ! neuron recognition GO:0008038 40 16 0,000 0,09376344 0,13506137 ! tissue regeneration GO:0042246 27 16 0,000 0,09376344 0,13498178 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,09376344 0,13490229 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,09376344 0,13482289 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,09376344 0,13474358 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,09376344 0,13466436 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,09376344 0,13458524 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09376344 0,13450621 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,09376344 0,13442728 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,09376344 0,13434844 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,09376344 0,13426969 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,09376344 0,13419103 ! peptide hormone processing GO:0016486 27 16 0,000 0,09376344 0,13411246 ! hemostasis GO:0007599 165 85 1,000 0,0961008 0,13737522 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,0961008 0,13729489 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 0,0961008 0,13721464 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,09800702 0,13985464 GO:0002696|positive regulation of leukocyte activation, ! positive regulation of cell killing GO:0031343 36 17 0,000 0,09932411 0,14165138 ! metencephalon development GO:0022037 32 17 0,000 0,09932411 0,14156873 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,09932411 0,14148618 ! signal complex assembly GO:0007172 47 17 0,000 0,09932411 0,14140373 ! filopodium assembly GO:0046847 42 17 0,000 0,09932411 0,14132138 ! gene silencing by RNA GO:0031047 38 17 0,000 0,09932411 0,14123912 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,09932411 0,14115695 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,09932411 0,14107489 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,09932411 0,14099291 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,09932411 0,14091104 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,09932411 0,14082925 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,09932411 0,14074757 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,09932411 0,14066597 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,09932411 0,14058448 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,09932411 0,14050307 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,09932411 0,14042176 ! NAD metabolic process GO:0019674 33 17 0,000 0,09932411 0,14034055 ! membrane budding GO:0006900 42 17 0,000 0,09932411 0,14025943 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,09932411 0,1401784 ! regulation of protein binding GO:0043393 33 17 0,000 0,09932411 0,14009746 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,09932411 0,14001662 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,09932411 0,13993587 ! genitalia development GO:0048806 32 17 0,000 0,09932411 0,13985522 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,09932411 0,13977466 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,09932411 0,13969419 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,09932411 0,13961381 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,09932411 0,13953353 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,09932411 0,13945334 ! steroid catabolic process GO:0006706 34 17 0,000 0,09932411 0,13937324 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,09932411 0,13929323 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,09932411 0,13921331 ! gas transport GO:0015669 26 17 0,000 0,09932411 0,13913349 ! organic cation transport GO:0015695 32 17 0,000 0,09932411 0,13905376 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,09932411 0,13897412 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,09932411 0,13889457 ! neuropeptide signaling pathway GO:0007218 125 87 1,000 0,09992391 0,13965339 ! nucleosome assembly GO:0006334 126 87 1,000 0,09992391 0,13957354 ! chromatin assembly GO:0031497 128 88 1,000 0,10185128 0,14218439 ! tube morphogenesis GO:0035239 194 89 1,000 0,10378893 0,1448066 ! regulation of neurological system process GO:0031644 175 89 1,000 0,10378893 0,14472395 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,10485082 0,14612125 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,10485082 0,14603794 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,10485082 0,14595473 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,10485082 0,14587161 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,10485082 0,14578859 ! adult walking behavior GO:0007628 36 18 0,000 0,10485082 0,14570566 ! patterning of blood vessels GO:0001569 43 18 0,000 0,10485082 0,14562283 ! heart looping GO:0001947 34 18 0,000 0,10485082 0,14554009 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,10485082 0,14545744 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,10485082 0,14537489 ! centrosome cycle GO:0007098 26 18 0,000 0,10485082 0,14529243 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,10485082 0,14521006 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,10485082 0,14512779 ! glycine metabolic process GO:0006544 30 18 0,000 0,10485082 0,14504561 ! glutamine metabolic process GO:0006541 29 18 0,000 0,10485082 0,14496353 ! response to retinoic acid GO:0032526 31 18 0,000 0,10485082 0,14488153 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,10485082 0,14479963 ! DNA integration GO:0015074 32 18 0,000 0,10485082 0,14471783 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,10485082 0,14463611 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,10485082 0,14455449 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,10485082 0,14447296 ! neural crest cell migration GO:0001755 41 18 0,000 0,10485082 0,14439152 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,10485082 0,14431017 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,10485082 0,14422891 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,10485082 0,14414775 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,10485082 0,14406668 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,10485082 0,1439857 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,10485082 0,1439048 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,10485082 0,143824 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,10485082 0,1437433 ! detection of bacterium GO:0016045 22 18 0,000 0,10485082 0,14366268 ! defense response to virus GO:0051607 43 18 0,000 0,10485082 0,14358215 ! microspike assembly GO:0030035 46 18 0,000 0,10485082 0,14350171 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,10485082 0,14342136 ! defense response to bacterium GO:0042742 112 91 1,000 0,10769427 0,14722838 ! protein-DNA complex assembly GO:0065004 134 92 1,000 0,10966158 0,14983402 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,11034377 0,15068185 ! positive regulation of translation GO:0045727 31 19 0,000 0,11034377 0,15059767 ! negative regulation of defense response GO:0031348 27 19 0,000 0,11034377 0,15051358 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,11034377 0,15042959 ! neuron maturation GO:0042551 46 19 0,000 0,11034377 0,15034569 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,11034377 0,15026189 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,11034377 0,15017818 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,11034377 0,15009456 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,11034377 0,15001103 ! inositol metabolic process GO:0006020 33 19 0,000 0,11034377 0,1499276 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,11034377 0,14984426 ! memory GO:0007613 34 19 0,000 0,11034377 0,14976102 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,11034377 0,14967786 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,11034377 0,1495948 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,11034377 0,14951183 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,11034377 0,14942895 ! pigmentation during development GO:0048066 42 19 0,000 0,11034377 0,14934616 ! response to vitamin A GO:0033189 32 19 0,000 0,11034377 0,14926347 ! heme metabolic process GO:0042168 40 19 0,000 0,11034377 0,14918087 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,11034377 0,14909836 ! response to fungus GO:0009620 26 19 0,000 0,11034377 0,14901594 ! peptide cross-linking GO:0018149 39 19 0,000 0,11034377 0,14893361 ! protein export from nucleus GO:0006611 40 19 0,000 0,11034377 0,14885137 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,11034377 0,14876922 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,11034377 0,14868716 ! visual learning GO:0008542 38 19 0,000 0,11034377 0,1486052 ! cellular pigmentation GO:0033059 37 19 0,000 0,11034377 0,14852332 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,11034377 0,14844154 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,11034377 0,14835984 ! vitamin transport GO:0051180 31 19 0,000 0,11034377 0,14827823 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,11034377 0,14819672 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,11034377 0,14811529 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,11034377 0,14803395 ! cilium assembly GO:0042384 38 19 0,000 0,11034377 0,1479527 ! peptide hormone secretion GO:0030072 32 19 0,000 0,11034377 0,14787155 ! regulation of defense response GO:0031347 171 95 1,000 0,11561974 0,15485693 ! nucleosome organization GO:0034728 143 95 1,000 0,11561974 0,15477207 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,11561974 0,15468731 ! protein secretion GO:0009306 45 20 0,000 0,11580317 0,15484791 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,11580317 0,1547632 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,11580317 0,15467859 ! positive regulation of ossification GO:0045778 50 20 0,000 0,11580317 0,15459406 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,11580317 0,15450963 ! skin development GO:0043588 42 20 0,000 0,11580317 0,15442529 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,11580317 0,15434104 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,11580317 0,15425689 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,11580317 0,15417282 ! response to vitamin GO:0033273 36 20 0,000 0,11580317 0,15408885 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,11580317 0,15400497 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,11580317 0,15392118 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,11580317 0,15383748 ! bile acid metabolic process GO:0008206 34 20 0,000 0,11580317 0,15375388 ! retinoid metabolic process GO:0001523 34 20 0,000 0,11580317 0,15367036 GO:0016101|diterpenoid metabolic process, ! DNA duplex unwinding GO:0032508 30 20 0,000 0,11580317 0,15358693 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,11580317 0,1535036 GO:0030968|endoplasmic reticulum unfolded protein response, ! body fluid secretion GO:0007589 33 20 0,000 0,11580317 0,15342035 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,11580317 0,1533372 ! peptide secretion GO:0002790 38 20 0,000 0,11580317 0,15325413 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,11580317 0,15317116 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,11580317 0,15308828 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,11580317 0,15300548 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,11580317 0,15292277 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,11580317 0,15284016 ! cell-cell junction organization GO:0045216 43 20 0,000 0,11580317 0,15275763 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,11580317 0,15267519 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,11580317 0,15259284 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,11580317 0,15251058 ! regulation of glucose import GO:0046324 30 20 0,000 0,11580317 0,15242841 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,11580317 0,15234633 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,11580317 0,15226433 ! negative regulation of translation GO:0017148 32 20 0,000 0,11580317 0,15218243 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,11580317 0,15210061 ! sex differentiation GO:0007548 171 96 1,000 0,11762392 0,15440905 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 0,11963686 0,15696716 ! regulation of cell killing GO:0031341 46 21 0,000 0,12122921 0,158971 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,12122921 0,15888571 ! hormone secretion GO:0046879 39 21 0,000 0,12122921 0,15880052 ! cAMP metabolic process GO:0046058 41 21 0,000 0,12122921 0,15871542 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,12122921 0,15863041 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,12122921 0,15854549 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,12122921 0,15846066 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,12122921 0,15837592 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,12122921 0,15829127 ! plasma membrane fusion GO:0045026 33 21 0,000 0,12122921 0,15820671 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,12122921 0,15812225 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,12122921 0,15803787 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,12122921 0,15795358 ! sensory perception of pain GO:0019233 33 21 0,000 0,12122921 0,15786939 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,12122921 0,15778528 ! collagen fibril organization GO:0030199 62 21 0,000 0,12122921 0,15770126 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,12122921 0,15761733 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,12122921 0,15753349 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,12122921 0,15744974 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,12122921 0,15736608 ! collagen catabolic process GO:0030574 29 21 0,000 0,12122921 0,15728251 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,12122921 0,15719903 GO:0043450|alkene biosynthetic process, ! sperm-egg recognition GO:0035036 23 21 0,000 0,12122921 0,15711563 ! actin filament-based movement GO:0030048 47 21 0,000 0,12122921 0,15703233 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,12122921 0,15694911 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,12662211 0,16384419 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,12662211 0,16375745 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,12662211 0,16367081 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,12662211 0,16358425 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,12662211 0,16349779 ! microtubule-based transport GO:0010970 59 22 0,000 0,12662211 0,16341142 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,12662211 0,16332515 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,12662211 0,16323896 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,12662211 0,16315286 ! cellular response to starvation GO:0009267 37 22 0,000 0,12662211 0,16306686 ! vacuolar transport GO:0007034 41 22 0,000 0,12662211 0,16298094 ! central nervous system neuron development GO:0021954 47 22 0,000 0,12662211 0,16289512 ! fucose metabolic process GO:0006004 44 22 0,000 0,12662211 0,16280938 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,12662211 0,16272374 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,12662211 0,16263818 ! cell aging GO:0007569 48 22 0,000 0,12662211 0,16255272 ! stem cell differentiation GO:0048863 57 22 0,000 0,12662211 0,16246735 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,12662211 0,16238206 ! cytolysis GO:0019835 27 22 0,000 0,12662211 0,16229687 ! renal system process GO:0003014 42 22 0,000 0,12662211 0,16221176 ! vasodilation GO:0042311 40 22 0,000 0,12662211 0,16212674 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,12662211 0,16204182 ! G1 phase GO:0051318 44 22 0,000 0,12662211 0,16195698 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,12662211 0,16187223 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,12662211 0,16178757 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,12662211 0,16170299 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,12662211 0,16161851 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,12662211 0,16153411 ! sarcomere organization GO:0045214 32 22 0,000 0,12662211 0,1614498 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,12662211 0,16136558 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,12662211 0,16128145 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,12662211 0,16119741 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,12662211 0,16111345 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,12662211 0,16102958 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,12662211 0,1609458 ! protein stabilization GO:0050821 41 22 0,000 0,12662211 0,1608621 ! positive regulation of DNA replication GO:0045740 44 23 0,000 0,13198207 0,1675843 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,13198207 0,16749725 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,13198207 0,16741028 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,13198207 0,1673234 ! gluconeogenesis GO:0006094 38 23 0,000 0,13198207 0,16723662 ! glycerol metabolic process GO:0006071 40 23 0,000 0,13198207 0,16714992 ! viral genome replication GO:0019079 44 23 0,000 0,13198207 0,16706332 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,13198207 0,1669768 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,13198207 0,16689037 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,13198207 0,16680403 ! regeneration GO:0031099 42 23 0,000 0,13198207 0,16671779 ! axis specification GO:0009798 43 23 0,000 0,13198207 0,16663163 ! visual behavior GO:0007632 46 23 0,000 0,13198207 0,16654556 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,13198207 0,16645958 ! response to ethanol GO:0045471 47 23 0,000 0,13198207 0,16637368 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,13198207 0,16628788 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,13198207 0,16620216 ! peroxisome organization GO:0007031 43 23 0,000 0,13198207 0,16611654 ! lysosome organization GO:0007040 47 23 0,000 0,13198207 0,166031 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,13198207 0,16594555 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,13198207 0,16586018 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,13198207 0,16577491 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,13198207 0,16568972 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,13198207 0,16560462 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,13198207 0,16551961 ! DNA modification GO:0006304 36 23 0,000 0,13198207 0,16543468 ! fatty acid transport GO:0015908 47 23 0,000 0,13198207 0,16534985 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,13198207 0,16526509 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,13198207 0,16518043 ! hormone transport GO:0009914 41 23 0,000 0,13198207 0,16509585 ! cell-cell recognition GO:0009988 28 23 0,000 0,13198207 0,16501136 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,13198207 0,16492696 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,13198207 0,16484264 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,13198207 0,16475841 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,13730928 0,17132103 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,13730928 0,17123358 GO:0016444|somatic cell DNA recombination, ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,13730928 0,17114621 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,13730928 0,17105894 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,13730928 0,17097175 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,13730928 0,17088466 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,13730928 0,17079765 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,13730928 0,17071073 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,13730928 0,1706239 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,13730928 0,17053715 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,13730928 0,1704505 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,13730928 0,17036393 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,13730928 0,17027745 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,13730928 0,17019106 GO:0051693|actin filament capping, ! sex determination GO:0007530 48 24 0,000 0,13730928 0,17010476 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,13730928 0,17001854 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,13730928 0,16993241 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,13730928 0,16984637 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,13730928 0,16976041 ! membrane depolarization GO:0051899 45 24 0,000 0,13730928 0,16967455 ! oogenesis GO:0048477 44 24 0,000 0,13730928 0,16958877 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,13730928 0,16950307 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,13730928 0,16941746 ! platelet activation GO:0030168 41 24 0,000 0,13730928 0,16933194 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,13730928 0,16924651 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,13730928 0,16916116 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,13730928 0,1690759 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,13730928 0,16899072 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,13730928 0,16890563 ! regulation of amine transport GO:0051952 41 24 0,000 0,13730928 0,16882062 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,14260395 0,17524218 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,14260395 0,17515407 ! leukocyte adhesion GO:0007159 55 25 0,000 0,14260395 0,17506606 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,14260395 0,17497813 ! phototransduction GO:0007602 37 25 0,000 0,14260395 0,17489029 ! keratinization GO:0031424 37 25 0,000 0,14260395 0,17480253 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,14260395 0,17471487 ! vacuole organization GO:0007033 49 25 0,000 0,14260395 0,17462729 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,14260395 0,1745398 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,14260395 0,1744524 ! receptor metabolic process GO:0043112 53 25 0,000 0,14260395 0,17436509 ! chromosome condensation GO:0030261 48 25 0,000 0,14260395 0,17427786 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,14260395 0,17419073 ! interaction with host GO:0051701 66 25 0,000 0,14260395 0,17410367 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,14260395 0,17401671 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,14260395 0,17392983 ! immunoglobulin production GO:0002377 62 25 0,000 0,14260395 0,17384304 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,14260395 0,17375633 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,14260395 0,17366972 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,14260395 0,17358318 ! liver development GO:0001889 55 25 0,000 0,14260395 0,17349674 ! protein tetramerization GO:0051262 57 25 0,000 0,14260395 0,17341038 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,14786627 0,17972005 ! initiation of viral infection GO:0019059 60 26 0,000 0,14786627 0,17963068 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,14786627 0,1795414 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,14786627 0,17945221 ! molting cycle process GO:0022404 52 26 0,000 0,14786627 0,17936311 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,14786627 0,17927409 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,14786627 0,17918517 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,14786627 0,17909633 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,14786627 0,17900758 GO:0051297|centrosome organization, ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,14786627 0,17891892 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,14786627 0,17883035 ! digestive system process GO:0022600 49 26 0,000 0,14786627 0,17874186 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,14786627 0,17865346 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,14786627 0,17856515 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,14786627 0,17847693 ! osteoblast differentiation GO:0001649 63 26 0,000 0,14786627 0,17838879 ! neural crest cell development GO:0014032 59 26 0,000 0,14786627 0,17830074 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,14786627 0,17821278 ! negative regulation of cell development GO:0010721 83 26 0,000 0,14786627 0,1781249 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,14786627 0,17803711 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,14786627 0,17794941 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,14786627 0,17786179 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,14786627 0,17777426 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,14786627 0,17768682 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,14786627 0,17759946 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,14786627 0,17751219 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,14786627 0,177425 ! blastocyst development GO:0001824 50 26 0,000 0,14786627 0,1773379 ! telomere organization GO:0032200 46 26 0,000 0,14786627 0,17725088 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,14786627 0,17716395 ! neural tube closure GO:0001843 58 26 0,000 0,14786627 0,17707711 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,14786627 0,17699035 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,14786627 0,17690367 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,15309644 0,18307127 ! embryonic pattern specification GO:0009880 49 27 0,000 0,15309644 0,1829817 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,15309644 0,18289223 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,15309644 0,18280284 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,15309644 0,18271353 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,15309644 0,18262432 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,15309644 0,18253519 ! superoxide metabolic process GO:0006801 41 27 0,000 0,15309644 0,18244615 ! tube lumen formation GO:0035148 59 27 0,000 0,15309644 0,18235719 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,15309644 0,18226832 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,15309644 0,18217954 ! response to starvation GO:0042594 47 27 0,000 0,15309644 0,18209085 ! response to toxin GO:0009636 49 27 0,000 0,15309644 0,18200224 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,15309644 0,18191372 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,15309644 0,18182528 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,15309644 0,18173693 ! leukocyte proliferation GO:0070661 59 27 0,000 0,15309644 0,18164867 GO:0032943|mononuclear cell proliferation, ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,15829465 0,18772516 ! vesicle docking GO:0048278 55 28 0,000 0,15829465 0,18763408 ! circadian rhythm GO:0007623 56 28 0,000 0,15829465 0,18754308 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,15829465 0,18745218 ! fat cell differentiation GO:0045444 57 28 0,000 0,15829465 0,18736136 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,15829465 0,18727062 ! sperm motility GO:0030317 37 28 0,000 0,15829465 0,18717998 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,15829465 0,18708942 ! base-excision repair GO:0006284 41 28 0,000 0,15829465 0,18699895 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,15829465 0,18690857 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,15829465 0,18681828 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,15829465 0,18672807 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,15829465 0,18663795 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,15829465 0,18654792 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,15829465 0,18645797 ! glutathione metabolic process GO:0006749 42 28 0,000 0,15829465 0,18636812 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,15829465 0,18627834 ! lipid oxidation GO:0034440 48 28 0,000 0,15829465 0,18618866 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,15829465 0,18609906 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,15829465 0,18600954 ! translational initiation GO:0006413 66 29 0,000 0,16346111 0,19198821 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,16346111 0,19189596 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,16346111 0,19180379 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,16346111 0,19171171 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,16346111 0,19161971 ! primary neural tube formation GO:0014020 61 29 0,000 0,16346111 0,19152781 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,16346111 0,19143599 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,16346111 0,19134427 ! synaptogenesis GO:0007416 46 29 0,000 0,16346111 0,19125263 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,16346111 0,19116107 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,16346111 0,19106961 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,16346111 0,19097823 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,16346111 0,19088694 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,16859599 0,1967893 ! phenol metabolic process GO:0018958 56 30 0,000 0,16859599 0,19669533 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,16859599 0,19660144 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,16859599 0,19650764 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,16859599 0,19641393 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,16859599 0,19632031 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,16859599 0,19622678 ! acute-phase response GO:0006953 50 30 0,000 0,16859599 0,19613334 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,16859599 0,19603999 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,16859599 0,19594672 ! myofibril assembly GO:0030239 50 30 0,000 0,16859599 0,19585355 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,16859599 0,19576046 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,16859599 0,19566746 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,16859599 0,19557455 ! cell fate determination GO:0001709 64 30 0,000 0,16859599 0,19548173 ! phospholipid transport GO:0015914 65 30 0,000 0,16859599 0,195389 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,16859599 0,19529635 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,16859599 0,1952038 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,16859599 0,19511133 ! regulation of coagulation GO:0050818 52 30 0,000 0,16859599 0,19501894 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,1736995 0,20082721 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,1736995 0,20073221 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,1736995 0,2006373 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,1736995 0,20054248 ! regulation of innate immune response GO:0045088 57 31 0,000 0,1736995 0,20044775 ! peptide transport GO:0015833 60 31 0,000 0,1736995 0,20035311 ! male gonad development GO:0008584 56 31 0,000 0,1736995 0,20025856 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,1736995 0,2001641 ! detection of light stimulus GO:0009583 44 31 0,000 0,1736995 0,20006973 ! natural killer cell activation GO:0030101 50 31 0,000 0,1736995 0,19997544 ! cofactor catabolic process GO:0051187 54 31 0,000 0,1736995 0,19988125 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,1736995 0,19978714 ! response to heat GO:0009408 54 31 0,000 0,1736995 0,19969312 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,1736995 0,19959919 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,17877183 0,20533126 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,17877183 0,20523477 ! collagen metabolic process GO:0032963 49 32 0,000 0,17877183 0,20513837 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,17877183 0,20504206 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,17877183 0,20494584 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,17877183 0,20484971 ! muscle cell development GO:0055001 52 32 0,000 0,17877183 0,20475367 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,17877183 0,20465772 ! BMP signaling pathway GO:0030509 71 32 0,000 0,17877183 0,20456186 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,17877183 0,2044661 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,17877183 0,20437042 ! gene silencing GO:0016458 71 32 0,000 0,17877183 0,20427483 ! regulation of pH GO:0006885 56 33 0,000 0,18381316 0,20993714 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,18381316 0,20983904 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,18381316 0,20974103 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,18381316 0,20964311 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,18381316 0,20954529 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,18381316 0,20944755 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,18381316 0,20934991 ! response to ionizing radiation GO:0010212 74 33 0,000 0,18381316 0,20925235 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,18381316 0,20915489 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,18381316 0,20905752 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,18381316 0,20896024 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,18381316 0,20886305 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,18882368 0,21445665 ! post-embryonic development GO:0009791 76 34 0,000 0,18882368 0,214357 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,18882368 0,21425744 ! cholesterol transport GO:0030301 62 34 0,000 0,18882368 0,21415797 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,18882368 0,21405859 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,18882368 0,21395931 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,18882368 0,21386011 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,18882368 0,21376101 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,18882368 0,213662 ! adult locomotory behavior GO:0008344 62 34 0,000 0,18882368 0,21356308 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,19380359 0,21909402 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,19380359 0,21899268 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,19380359 0,21889143 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,19380359 0,21879028 ! membrane docking GO:0022406 69 35 0,000 0,19380359 0,21868922 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,19380359 0,21858826 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,19380359 0,21848739 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,19380359 0,21838661 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,19380359 0,21828592 ! ceramide metabolic process GO:0006672 72 35 0,000 0,19380359 0,21818533 ! sterol transport GO:0015918 63 35 0,000 0,19380359 0,21808483 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,19380359 0,21798442 ! placenta development GO:0001890 53 35 0,000 0,19380359 0,21788411 ! regulation of muscle development GO:0048634 82 36 0,000 0,19875306 0,22334578 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,19875306 0,2232431 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,19875306 0,2231405 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,19875306 0,223038 ! positive regulation of cell development GO:0010720 85 36 0,000 0,19875306 0,2229356 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,19875306 0,22283329 ! aerobic respiration GO:0009060 56 36 0,000 0,19875306 0,22273107 ! cytokine production GO:0001816 68 36 0,000 0,19875306 0,22262895 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,19875306 0,22252692 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,19875306 0,22242498 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,20367229 0,22782573 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,20367229 0,22772146 ! actomyosin structure organization GO:0031032 68 37 0,000 0,20367229 0,22761729 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,20367229 0,22751321 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,20367229 0,22740923 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,20367229 0,22730534 ! positive regulation of DNA metabolic process GO:0051054 77 38 0,000 0,20856145 0,23265553 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,20856145 0,23254935 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,20856145 0,23244326 ! organic anion transport GO:0015711 82 38 0,000 0,20856145 0,23233726 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,20856145 0,23223137 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,20856145 0,23212557 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,20856145 0,23201986 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,20856145 0,23191426 ! spermatid development GO:0007286 69 38 0,000 0,20856145 0,23180874 ! pigment metabolic process GO:0042440 87 38 0,000 0,20856145 0,23170333 ! neural tube formation GO:0001841 79 38 0,000 0,20856145 0,23159801 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,21342073 0,23688634 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,21342073 0,23677876 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,21342073 0,23667128 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,21342073 0,2365639 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,21342073 0,23645662 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,21825031 0,24169787 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,21825031 0,24158836 ! lipid homeostasis GO:0055088 75 40 0,000 0,21825031 0,24147894 ! mismatch repair GO:0006298 58 40 0,000 0,21825031 0,24136963 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,21825031 0,24126041 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,21825031 0,24115129 ! RNA export from nucleus GO:0006405 61 41 0,000 0,22305037 0,24634361 ! mRNA catabolic process GO:0006402 79 41 0,000 0,22305037 0,24623229 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,22305037 0,24612108 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,22305037 0,24600996 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,22305037 0,24589894 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,22305037 0,24578803 ! feeding behavior GO:0007631 69 41 0,000 0,22305037 0,24567721 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,22305037 0,2455665 ! mesenchymal cell development GO:0014031 94 41 0,000 0,22305037 0,24545588 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,22305037 0,24534537 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,22305037 0,24523495 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,22305037 0,24512463 ! spermatid differentiation GO:0048515 73 41 0,000 0,22305037 0,24501442 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,22305037 0,2449043 ! RNA modification GO:0009451 64 41 0,000 0,22305037 0,24479428 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,2278211 0,2499178 ! organic ether metabolic process GO:0018904 59 42 0,000 0,2278211 0,24980563 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,2278211 0,24969356 ! T cell differentiation GO:0030217 93 42 0,000 0,2278211 0,24958159 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,2278211 0,24946972 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,2278211 0,24935795 ! regulation of protein secretion GO:0050708 77 42 0,000 0,2278211 0,24924628 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,2278211 0,24913471 ! epithelial cell differentiation GO:0030855 83 43 0,000 0,23256266 0,25420608 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,23256266 0,25409239 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,23256266 0,2539788 ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,23256266 0,25386532 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,23256266 0,25375193 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,23256266 0,25363865 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,23256266 0,25352547 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,23256266 0,25341239 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,23256266 0,25329941 ! ion transmembrane transport GO:0034220 79 43 0,000 0,23256266 0,25318653 ! neuron migration GO:0001764 85 43 0,000 0,23256266 0,25307376 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,23727524 0,25808701 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,23727524 0,25797215 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,23727524 0,25785739 ! double-strand break repair GO:0006302 85 44 0,000 0,23727524 0,25774274 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,24195902 0,26271372 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,24195902 0,26259701 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,24195902 0,26248041 ! biopolymer methylation GO:0043414 91 45 0,000 0,24195902 0,2623639 ! B cell differentiation GO:0030183 124 45 0,000 0,24195902 0,26224751 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,24195902 0,26213121 ! female gamete generation GO:0007292 71 45 0,000 0,24195902 0,26201502 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,24195902 0,26189893 ! polyol metabolic process GO:0019751 77 45 0,000 0,24195902 0,26178294 ! maintenance of location in cell GO:0051651 101 45 0,000 0,24195902 0,26166705 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,24661416 0,26658336 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,24661416 0,26646545 ! glycolysis GO:0006096 71 46 0,000 0,24661416 0,26634765 ! regulation of gene-specific transcription GO:0032583 102 46 0,000 0,24661416 0,26622996 ! leukocyte migration GO:0050900 75 46 0,000 0,24661416 0,26611236 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,24661416 0,26599488 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,24661416 0,26587749 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,24661416 0,26576021 ! positive regulation of defense response GO:0031349 88 48 0,000 0,25583925 0,27557993 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,25583925 0,27545848 ! mitochondrial transport GO:0006839 94 48 0,000 0,25583925 0,27533713 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,25583925 0,27521589 ! endosome transport GO:0016197 127 48 0,000 0,25583925 0,27509476 ! male sex differentiation GO:0046661 93 48 0,000 0,25583925 0,27497373 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,25583925 0,27485281 ! regulation of inflammatory response GO:0050727 84 48 0,000 0,25583925 0,27473199 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,25583925 0,27461128 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,25583925 0,27449068 ! methylation GO:0032259 97 48 0,000 0,25583925 0,27437019 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,26040954 0,27914897 ! JNK cascade GO:0007254 106 49 0,000 0,26040954 0,27902654 ! protein homooligomerization GO:0051260 84 49 0,000 0,26040954 0,27890421 ! regulation of ion transport GO:0043269 86 50 0,000 0,26495189 0,28364481 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,26495189 0,28352057 ! regulation of ossification GO:0030278 123 50 0,000 0,26495189 0,28339644 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,26495189 0,28327241 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,26495189 0,2831485 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,26495189 0,28302469 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,26495189 0,28290099 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,26495189 0,2827774 ! viral infectious cycle GO:0019058 104 51 0,000 0,26946647 0,28747012 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,26946647 0,28734465 ! peptide metabolic process GO:0006518 80 51 0,000 0,26946647 0,28721928 ! response to temperature stimulus GO:0009266 84 51 0,000 0,26946647 0,28709402 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,27395345 0,29174729 ! Notch signaling pathway GO:0007219 111 52 0,000 0,27395345 0,29162016 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,27395345 0,29149315 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,27395345 0,29136625 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,27395345 0,29123946 ! excretion GO:0007588 87 52 0,000 0,27395345 0,29111278 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,27395345 0,29098621 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,27395345 0,29085974 ! respiratory electron transport chain GO:0022904 83 53 0,000 0,27841299 0,29546609 ! inner ear development GO:0048839 89 53 0,000 0,27841299 0,29533779 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,27841299 0,29520961 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,27841299 0,29508154 ! vesicle organization GO:0016050 127 53 0,000 0,27841299 0,29495357 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,27841299 0,29482572 ! regulation of translational initiation GO:0006446 87 54 0,000 0,28284527 0,29938951 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,28284527 0,29925985 ! neuromuscular process GO:0050905 107 54 0,000 0,28284527 0,2991303 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,28284527 0,29900086 ! membrane fusion GO:0006944 122 54 0,000 0,28284527 0,29887154 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,28284527 0,29874232 ! RNA catabolic process GO:0006401 103 55 0,000 0,28725045 0,30326398 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,28725045 0,30313298 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,28725045 0,30300209 ! cell recognition GO:0008037 98 55 0,000 0,28725045 0,30287132 ! cell maturation GO:0048469 107 55 0,000 0,28725045 0,30274066 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,28725045 0,30261011 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,28725045 0,30247967 ! glucose catabolic process GO:0006007 88 56 0,000 0,29162869 0,30695773 ! regulation of DNA replication GO:0006275 105 56 0,000 0,29162869 0,30682553 ! RNA elongation GO:0006354 90 56 0,000 0,29162869 0,30669345 ! chloride transport GO:0006821 102 57 0,000 0,29598016 0,31113577 ! heart morphogenesis GO:0003007 105 57 0,000 0,29598016 0,31100195 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,29598016 0,31086824 ! regulation of actin filament length GO:0030832 118 58 0,000 0,30030502 0,3152751 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,30030502 0,31513967 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,30030502 0,31500436 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,30030502 0,31486917 ! maintenance of location GO:0051235 124 58 0,000 0,30030502 0,31473409 ! nuclear export GO:0051168 110 59 0,000 0,30460343 0,31910214 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,30887556 0,32343892 ! regulation of endocytosis GO:0030100 104 60 0,000 0,30887556 0,32330034 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,30887556 0,32316188 ! adult behavior GO:0030534 104 60 0,000 0,30887556 0,32302354 ! regulation of cellular component size GO:0032535 125 61 0,000 0,31312156 0,32732391 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,31312156 0,32718391 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,31312156 0,32704402 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,31312156 0,32690426 ! regulation of heart contraction GO:0008016 123 61 0,000 0,31312156 0,32676462 ! proton transport GO:0015992 117 61 0,000 0,31312156 0,3266251 ! negative regulation of response to stimulus GO:0048585 106 61 0,000 0,31312156 0,32648569 ! viral reproductive process GO:0022415 132 62 0,000 0,3173416 0,33074467 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,3173416 0,33060363 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,3173416 0,33046271 ! tRNA processing GO:0008033 102 62 0,000 0,3173416 0,33032191 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,32153582 0,33454515 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,32153582 0,33440273 ! hydrogen transport GO:0006818 121 64 0,000 0,3257044 0,33859397 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,3257044 0,33844995 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,3257044 0,33830605 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,32984748 0,34246383 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,32984748 0,34231834 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,32984748 0,34217299 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,32984748 0,34202775 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,33396521 0,34615062 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,33396521 0,34600382 ! activation of MAPK activity GO:0000187 124 67 0,000 0,33805777 0,35009543 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,33805777 0,34994709 ! secondary metabolic process GO:0019748 125 67 0,000 0,33805777 0,34979887 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,33805777 0,34965077 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,34212529 0,35370803 ! hexose catabolic process GO:0019320 113 68 0,000 0,34212529 0,35355841 ! extracellular matrix organization GO:0030198 146 68 0,000 0,34212529 0,35340891 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,34212529 0,35325954 ! viral reproduction GO:0016032 142 68 0,000 0,34212529 0,3531103 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,34616793 0,35713186 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,34616793 0,35698111 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,34616793 0,35683048 ! developmental maturation GO:0021700 128 69 0,000 0,34616793 0,35667998 ! single fertilization GO:0007338 83 69 0,000 0,34616793 0,35652961 ! cell redox homeostasis GO:0045454 114 70 0,000 0,35018584 0,3605158 ! germ cell development GO:0007281 133 70 0,000 0,35018584 0,36036394 ! activation of immune response GO:0002253 120 70 0,000 0,35018584 0,36021221 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,35018584 0,36006061 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,35417917 0,36401334 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,35417917 0,36386027 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,35417917 0,36370732 ! B cell activation GO:0042113 179 72 0,000 0,35814807 0,36762846 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,35814807 0,36747406 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,35814807 0,36731979 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,3620927 0,37120959 ! acute inflammatory response GO:0002526 118 74 0,000 0,36601319 0,3750714 ! amino acid transport GO:0006865 148 74 0,000 0,36601319 0,37491414 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,36601319 0,37475701 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,3699097 0,37858793 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,37378237 0,38239126 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,37378237 0,38223119 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,37378237 0,38207127 ! amine catabolic process GO:0009310 136 77 0,000 0,37763134 0,38584415 ! neurotransmitter transport GO:0006836 142 77 0,000 0,37763134 0,38568285 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,37763134 0,38552168 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,37763134 0,38536064 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,37763134 0,38519974 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,38145677 0,38893943 ! antigen processing and presentation GO:0019882 117 78 0,000 0,38145677 0,38877717 ! fertilization GO:0009566 99 78 0,000 0,38145677 0,38861505 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,38525879 0,39232481 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,38525879 0,39216134 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,38525879 0,39199801 ! protein oligomerization GO:0051259 149 79 0,000 0,38525879 0,39183481 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,38903754 0,39551341 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,39279318 0,39916545 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,40023564 0,40655953 ! exocytosis GO:0006887 153 83 0,000 0,40023564 0,40639056 ! response to drug GO:0042493 149 83 0,000 0,40023564 0,40622172 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,40023564 0,40605302 ! inorganic anion transport GO:0015698 156 83 0,000 0,40023564 0,40588447 ! T cell activation GO:0042110 189 84 0,000 0,40392275 0,40945365 ! response to nutrient GO:0007584 135 84 0,000 0,40392275 0,40928382 ! digestion GO:0007586 130 84 0,000 0,40392275 0,40911413 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,4075873 0,41265469 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,4075873 0,41248375 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,41122942 0,4159973 ! regulation of lyase activity GO:0051339 169 86 0,000 0,41122942 0,41582512 ! alcohol catabolic process GO:0046164 142 87 0,000 0,41484925 0,41931184 ! cellular respiration GO:0045333 143 88 0,000 0,41844693 0,42277331 ! amine biosynthetic process GO:0009309 146 88 0,000 0,41844693 0,42259853 ! sensory perception of smell GO:0007608 117 88 0,000 0,41844693 0,42242391 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,41844693 0,42224942 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,42202259 0,42568175 ! cellular defense response GO:0006968 123 89 0,000 0,42202259 0,42550606 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,42557637 0,42891215 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,42557637 0,42873528 ! response to unfolded protein GO:0006986 139 90 0,000 0,42557637 0,42855856 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,42910839 0,43193729 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine transport GO:0015837 181 93 0,000 0,43610771 0,43880195 ! vitamin metabolic process GO:0006766 153 93 0,000 0,43610771 0,4386213 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,43957527 0,44192691 ! female pregnancy GO:0007565 166 94 0,000 0,43957527 0,44174512 ! sterol metabolic process GO:0016125 166 94 0,000 0,43957527 0,44156348 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,43957527 0,44138199 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,44302161 0,44465973 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,44302161 0,44447712 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,44302161 0,44429466 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,44302161 0,44411235 ! response to protein stimulus GO:0051789 158 96 0,000 0,44644685 0,44736245 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,44985112 0,45058888 ! leukocyte differentiation GO:0002521 232 98 0,000 0,45323455 0,4537918 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,45323455 0,4536059 ! positive regulation of immune response GO:0050778 175 100 0,000 0,45993939 0,46012774 ! hormone metabolic process GO:0042445 171 100 0,000 0,45993939 0,45993939