pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6483-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 5,000 7,274E-12 1,75E-08 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 8,000 4,347E-11 5,229E-08 ! phospholipid dephosphorylation GO:0046839 12 5 3,000 5,483E-09 4,397E-06 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 1,637E-08 9,849E-06 ! auditory receptor cell differentiation GO:0042491 32 16 4,000 2,594E-08 1,248E-05 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 4,000 3,658E-08 1,467E-05 ! macrophage differentiation GO:0030225 11 7 3,000 3,803E-08 1,307E-05 ! negative regulation of focal adhesion formation GO:0051895 20 7 3,000 3,803E-08 1,144E-05 ! regulation of focal adhesion formation GO:0051893 22 8 3,000 7,572E-08 2,024E-05 ! inner ear receptor cell differentiation GO:0060113 37 20 4,000 9,036E-08 2,174E-05 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 4,000 1,18E-07 2,582E-05 ! lung development GO:0030324 144 67 6,000 1,286E-07 2,578E-05 ! mechanoreceptor differentiation GO:0042490 40 22 4,000 1,52E-07 2,814E-05 ! respiratory tube development GO:0030323 150 70 6,000 1,746E-07 3,001E-05 ! respiratory system development GO:0060541 153 72 6,000 2,125E-07 3,409E-05 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 3,000 2,251E-07 3,385E-05 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 3,000 3,521E-07 4,983E-05 GO:0010812|negative regulation of cell-substrate adhesion, ! insulin receptor signaling pathway GO:0008286 64 26 4,000 3,727E-07 4,982E-05 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 2,000 1,912E-06 2,421E-04 ! cellular response to insulin stimulus GO:0032869 82 37 4,000 2,345E-06 2,821E-04 ! endothelial cell migration GO:0043542 28 17 3,000 2,471E-06 2,831E-04 ! inositol metabolic process GO:0006020 28 17 3,000 2,471E-06 2,703E-04 ! cardiac muscle tissue development GO:0048738 31 17 3,000 2,471E-06 2,585E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 3,000 2,471E-06 2,477E-04 ! myoblast cell fate commitment GO:0048625 16 6 2,000 3,808E-06 3,665E-04 ! nuclear migration GO:0007097 12 6 2,000 3,808E-06 3,524E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 3,808E-06 3,393E-04 GO:0031272|regulation of pseudopodium assembly, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 3,000 4,962E-06 4,264E-04 ! regulation of lipid kinase activity GO:0043550 13 7 2,000 6,635E-06 5,505E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 4,000 7,07E-06 5,67E-04 ! negative regulation of cell migration GO:0030336 115 46 4,000 7,07E-06 5,487E-04 ! response to insulin stimulus GO:0032868 95 46 4,000 7,07E-06 5,316E-04 ! myeloid leukocyte differentiation GO:0002573 40 23 3,000 8,947E-06 6,523E-04 ! regulation of cell-matrix adhesion GO:0001952 78 23 3,000 8,947E-06 6,331E-04 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 1,057E-05 7,267E-04 ! positive regulation of insulin secretion GO:0032024 15 8 2,000 1,057E-05 7,065E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 1,057E-05 6,874E-04 ! inner ear development GO:0048839 79 50 4,000 1,072E-05 6,79E-04 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 4,000 1,183E-05 7,301E-04 ! vasculogenesis GO:0001570 46 25 3,000 1,267E-05 7,619E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 2,000 1,579E-05 9,265E-04 ! RNA elongation GO:0006354 79 55 4,000 1,72E-05 9,853E-04 ! negative regulation of cell motion GO:0051271 134 55 4,000 1,72E-05 9,624E-04 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 3,000 1,741E-05 9,522E-04 ! lipid modification GO:0030258 97 57 4,000 2,051E-05 1,097E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 2,638E-05 1,38E-03 ! negative regulation of protein kinase cascade GO:0010741 68 30 3,000 2,682E-05 1,373E-03 ! response to peptide hormone stimulus GO:0043434 122 61 4,000 2,86E-05 1,434E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 2,000 3,075E-05 1,51E-03 ! positive regulation of peptide secretion GO:0002793 22 11 2,000 3,075E-05 1,48E-03 ! nucleus localization GO:0051647 19 11 2,000 3,075E-05 1,451E-03 ! ear development GO:0043583 103 62 4,000 3,096E-05 1,433E-03 ! steroid hormone receptor signaling pathway GO:0030518 129 63 4,000 3,347E-05 1,52E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 2,000 4,082E-05 1,819E-03 ! regulation of cell projection assembly GO:0060491 30 12 2,000 4,082E-05 1,786E-03 ! regulation of hormone metabolic process GO:0032350 26 12 2,000 4,082E-05 1,754E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 4,000 4,85E-05 2,047E-03 ! negative regulation of cell adhesion GO:0007162 81 35 3,000 5,01E-05 2,078E-03 ! regulation of monooxygenase activity GO:0032768 33 13 2,000 5,284E-05 2,155E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 3,000 6,263E-05 2,511E-03 ! regulation of protein stability GO:0031647 73 37 3,000 6,263E-05 2,47E-03 ! phosphoinositide metabolic process GO:0030384 128 72 4,000 6,388E-05 2,479E-03 ! regulation of RNA stability GO:0043487 32 14 2,000 6,697E-05 2,558E-03 ! carbohydrate homeostasis GO:0033500 53 38 3,000 6,968E-05 2,619E-03 GO:0042593|glucose homeostasis, ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 8,335E-05 3,085E-03 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 4,000 9,372E-05 3,417E-03 ! polyol metabolic process GO:0019751 66 41 3,000 9,43E-05 3,387E-03 ! filopodium assembly GO:0046847 32 16 2,000 1,021E-04 3,614E-03 ! cellular response to hormone stimulus GO:0032870 167 82 4,000 1,189E-04 4,146E-03 ! myoblast differentiation GO:0045445 45 17 2,000 1,235E-04 4,245E-03 ! microspike assembly GO:0030035 36 17 2,000 1,235E-04 4,185E-03 ! response to retinoic acid GO:0032526 26 18 2,000 1,476E-04 4,932E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 1,476E-04 4,864E-03 ! positive regulation of hormone secretion GO:0046887 32 19 2,000 1,745E-04 5,674E-03 ! response to vitamin A GO:0033189 27 19 2,000 1,745E-04 5,598E-03 ! estrogen receptor signaling pathway GO:0030520 38 19 2,000 1,745E-04 5,524E-03 ! positive regulation of cell cycle GO:0045787 89 48 3,000 1,756E-04 5,485E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 2,044E-04 6,305E-03 ! response to vitamin GO:0033273 31 20 2,000 2,044E-04 6,226E-03 ! pancreas development GO:0031016 35 20 2,000 2,044E-04 6,148E-03 ! peptidyl-serine modification GO:0018209 43 20 2,000 2,044E-04 6,072E-03 ! regulation of cell shape GO:0008360 125 51 3,000 2,224E-04 6,526E-03 ! transcription initiation GO:0006352 153 94 4,000 2,261E-04 6,555E-03 ! hindlimb morphogenesis GO:0035137 43 21 2,000 2,375E-04 6,802E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 4,000 2,376E-04 6,725E-03 ! covalent chromatin modification GO:0016569 101 52 3,000 2,399E-04 6,711E-03 ! response to UV GO:0009411 104 53 3,000 2,583E-04 7,143E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 2,738E-04 7,486E-03 ! interphase GO:0051325 213 98 4,000 2,746E-04 7,423E-03 ! Golgi vesicle transport GO:0048193 207 99 4,000 2,879E-04 7,695E-03 ! sex determination GO:0007530 47 23 2,000 3,135E-04 8,289E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 3,319E-04 8,679E-03 ! selenocysteine incorporation GO:0001514 12 5 1,000 3,319E-04 8,586E-03 GO:0006451|translational readthrough, ! glial cell fate commitment GO:0021781 13 5 1,000 3,319E-04 8,495E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 3,319E-04 8,405E-03 ! anagen GO:0042640 6 5 1,000 3,319E-04 8,318E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 3,319E-04 8,232E-03 ! response to food GO:0032094 6 5 1,000 3,319E-04 8,148E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 3,319E-04 8,066E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 1,000 3,319E-04 7,985E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 3,319E-04 7,906E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 3,319E-04 7,828E-03 ! phospholipid scrambling GO:0017121 8 5 1,000 3,319E-04 7,752E-03 ! positive regulation of cell migration GO:0030335 126 57 3,000 3,422E-04 7,916E-03 ! regulation of cellular catabolic process GO:0031329 52 24 2,000 3,568E-04 8,175E-03 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 3,568E-04 8,098E-03 ! establishment of organelle localization GO:0051656 109 59 3,000 3,907E-04 8,786E-03 ! regulation of insulin secretion GO:0050796 37 25 2,000 4,037E-04 8,994E-03 ! interaction with host GO:0051701 62 25 2,000 4,037E-04 8,911E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 4,544E-04 9,939E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 4,959E-04 0,01074932 ! male sex determination GO:0030238 15 6 1,000 4,959E-04 0,01065334 ! establishment of spindle localization GO:0051293 12 6 1,000 4,959E-04 0,01055907 GO:0051653|spindle localization, ! hair follicle maturation GO:0048820 7 6 1,000 4,959E-04 0,01046644 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 5,09E-04 0,01065014 ! fat cell differentiation GO:0045444 50 27 2,000 5,09E-04 0,01055832 ! positive regulation of cell motion GO:0051272 146 64 3,000 5,333E-04 0,0109668 ! myeloid cell differentiation GO:0030099 111 65 3,000 5,657E-04 0,01153479 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 5,677E-04 0,01147814 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 6,305E-04 0,01264183 ! regulation of peptide secretion GO:0002791 47 29 2,000 6,305E-04 0,01253735 ! cytokinesis during cell cycle GO:0033205 11 7 1,000 6,916E-04 0,01363983 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 6,916E-04 0,01352893 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 6,916E-04 0,01341983 ! mRNA stabilization GO:0048255 18 7 1,000 6,916E-04 0,01331247 GO:0043489|RNA stabilization, ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 6,916E-04 0,01320682 ! transcription from RNA polymerase I promoter GO:0006360 13 7 1,000 6,916E-04 0,01310282 ! regulation of respiratory burst GO:0060263 11 7 1,000 6,916E-04 0,01300046 ! metanephros development GO:0001656 74 32 2,000 8,45E-04 0,01576018 ! positive regulation of catabolic process GO:0009896 64 32 2,000 8,45E-04 0,01563895 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 9,186E-04 0,01687227 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 9,186E-04 0,01674445 ! T-helper 1 type immune response GO:0042088 12 8 1,000 9,186E-04 0,01661855 ! ER overload response GO:0006983 12 8 1,000 9,186E-04 0,01649453 ! regulation of vascular permeability GO:0043114 12 8 1,000 9,186E-04 0,01637235 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 1,000 9,186E-04 0,01625196 ! blastocyst growth GO:0001832 19 8 1,000 9,186E-04 0,01613334 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 9,186E-04 0,01601643 ! organelle localization GO:0051640 136 74 3,000 9,232E-04 0,01598072 ! cell-matrix adhesion GO:0007160 163 75 3,000 9,709E-04 0,01668523 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 1,011E-03 0,01724814 ! regulation of developmental growth GO:0048638 15 9 1,000 1,177E-03 0,01993605 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,177E-03 0,01979663 ! induction of positive chemotaxis GO:0050930 15 9 1,000 1,177E-03 0,01965916 ! regulation of glycolysis GO:0006110 21 9 1,000 1,177E-03 0,01952358 ! microtubule bundle formation GO:0001578 21 9 1,000 1,177E-03 0,01938985 ! regulation of Notch signaling pathway GO:0008593 22 9 1,000 1,177E-03 0,01925795 ! motor axon guidance GO:0008045 16 9 1,000 1,177E-03 0,01912783 ! protein heterooligomerization GO:0051291 16 9 1,000 1,177E-03 0,01899945 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 1,196E-03 0,01918135 ! cell-substrate adhesion GO:0031589 171 81 3,000 1,294E-03 0,02061179 ! glycogen metabolic process GO:0005977 61 37 2,000 1,296E-03 0,02051169 ! glucan metabolic process GO:0044042 62 38 2,000 1,401E-03 0,02203037 GO:0006073|cellular glucan metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 1,465E-03 0,02289051 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,465E-03 0,02274283 ! lung alveolus development GO:0048286 26 10 1,000 1,465E-03 0,02259705 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 1,465E-03 0,02245312 ! glucan biosynthetic process GO:0009250 14 10 1,000 1,465E-03 0,02231101 GO:0005978|glycogen biosynthetic process, ! regulation of bone resorption GO:0045124 25 10 1,000 1,465E-03 0,02217069 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 1,465E-03 0,02203212 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,465E-03 0,02189527 GO:0043470|regulation of carbohydrate catabolic process, ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 1,000 1,465E-03 0,02176012 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,465E-03 0,02162662 ! localization within membrane GO:0051668 20 10 1,000 1,465E-03 0,02149475 ! regulation of hormone secretion GO:0046883 62 40 2,000 1,627E-03 0,02372226 ! mesenchymal cell development GO:0014031 87 40 2,000 1,627E-03 0,02357935 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! cytokinesis GO:0000910 72 40 2,000 1,627E-03 0,02343816 ! negative regulation of muscle development GO:0048635 20 11 1,000 1,784E-03 0,025548 ! blood vessel remodeling GO:0001974 29 11 1,000 1,784E-03 0,02539682 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 1,784E-03 0,02524743 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,784E-03 0,02509979 ! DNA methylation GO:0006306 19 11 1,000 1,784E-03 0,02495386 GO:0006305|DNA alkylation, ! regulation of leukocyte migration GO:0002685 26 11 1,000 1,784E-03 0,02480961 ! regulation of embryonic development GO:0045995 27 11 1,000 1,784E-03 0,02466703 ! regulation of cell morphogenesis GO:0022604 215 89 3,000 1,831E-03 0,0251795 ! regulation of cell adhesion GO:0030155 212 89 3,000 1,831E-03 0,02503643 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 1,874E-03 0,02547769 ! neuron migration GO:0001764 79 42 2,000 1,874E-03 0,02533456 ! energy reserve metabolic process GO:0006112 74 43 2,000 2,006E-03 0,02696769 ! virus-host interaction GO:0019048 29 12 1,000 2,133E-03 0,02850462 ! regulation of B cell proliferation GO:0030888 20 12 1,000 2,133E-03 0,02834714 ! cartilage condensation GO:0001502 20 12 1,000 2,133E-03 0,02819138 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 2,133E-03 0,02803733 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,133E-03 0,02788496 ! entry into host cell GO:0030260 32 12 1,000 2,133E-03 0,02773423 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 26 12 1,000 2,133E-03 0,02758512 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,133E-03 0,0274376 ! T cell homeostasis GO:0043029 25 12 1,000 2,133E-03 0,02729166 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 2,133E-03 0,02714726 ! developmental growth GO:0048589 82 44 2,000 2,144E-03 0,02714986 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 2,151E-03 0,02709718 ! leukocyte differentiation GO:0002521 202 96 3,000 2,415E-03 0,03025986 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 2,437E-03 0,03037589 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 2,437E-03 0,03021931 ! positive regulation of protein transport GO:0051222 72 46 2,000 2,437E-03 0,03006434 ! plasma membrane organization GO:0007009 24 13 1,000 2,511E-03 0,03081936 ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 2,511E-03 0,03066292 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,511E-03 0,03050805 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! chromatin silencing GO:0006342 26 13 1,000 2,511E-03 0,03035475 ! regulation of mRNA stability GO:0043488 31 13 1,000 2,511E-03 0,03020297 ! positive regulation of DNA binding GO:0043388 73 47 2,000 2,592E-03 0,03102362 ! skeletal muscle tissue development GO:0007519 186 99 3,000 2,7E-03 0,03215721 GO:0060538|skeletal muscle organ development, ! cell cycle arrest GO:0007050 213 100 3,000 2,8E-03 0,03318314 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 2,918E-03 0,03441425 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 2,918E-03 0,03424637 GO:0060675|ureteric bud morphogenesis, ! regulation of cell projection organization GO:0031344 121 50 2,000 3,093E-03 0,03612723 ! histone modification GO:0016570 91 50 2,000 3,093E-03 0,0359527 ! regulation of gene expression, epigenetic GO:0040029 105 50 2,000 3,093E-03 0,03577985 ! positive regulation of binding GO:0051099 78 51 2,000 3,273E-03 0,03767416 ! epithelial tube morphogenesis GO:0060562 98 51 2,000 3,273E-03 0,03749476 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 3,354E-03 0,03824517 ! embryonic hindlimb morphogenesis GO:0035116 33 15 1,000 3,354E-03 0,03806477 ! histone deacetylation GO:0016575 20 15 1,000 3,354E-03 0,03788606 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 3,354E-03 0,03770902 ! lymphocyte homeostasis GO:0002260 30 15 1,000 3,354E-03 0,03753363 ! regulation of angiogenesis GO:0045765 114 52 2,000 3,458E-03 0,03852149 ! positive regulation of growth GO:0045927 90 52 2,000 3,458E-03 0,03834397 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,819E-03 0,04214422 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 3,819E-03 0,04195178 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 3,819E-03 0,04176109 GO:0031114|regulation of microtubule depolymerization, ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 3,819E-03 0,04157213 ! DNA replication initiation GO:0006270 27 16 1,000 3,819E-03 0,04138487 ! negative regulation of inflammatory response GO:0050728 22 16 1,000 3,819E-03 0,04119928 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 3,819E-03 0,04101536 ! cellular polysaccharide metabolic process GO:0044264 86 55 2,000 4,054E-03 0,04334559 ! skeletal muscle fiber development GO:0048741 111 56 2,000 4,265E-03 0,04540387 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 4,311E-03 0,0456952 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 1,000 4,311E-03 0,04549479 ! regulation of survival gene product expression GO:0045884 33 17 1,000 4,311E-03 0,04529612 ! DNA unwinding during replication GO:0006268 27 17 1,000 4,311E-03 0,04509918 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 4,311E-03 0,04490394 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 4,311E-03 0,04471039 ! muscle fiber development GO:0048747 112 57 2,000 4,483E-03 0,04629016 ! regulation of intracellular transport GO:0032386 101 57 2,000 4,483E-03 0,04609234 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 4,832E-03 0,04946821 ! positive regulation of proteolysis GO:0045862 31 18 1,000 4,832E-03 0,0492586 ! epidermis morphogenesis GO:0048730 40 18 1,000 4,832E-03 0,04905075 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 4,832E-03 0,04884466 ! positive regulation of secretion GO:0051047 95 59 2,000 4,939E-03 0,04971665 ! integrin-mediated signaling pathway GO:0007229 135 59 2,000 4,939E-03 0,0495095 ! kidney development GO:0001822 122 60 2,000 5,177E-03 0,05168004 ! negative regulation of defense response GO:0031348 25 19 1,000 5,38E-03 0,05348465 ! lipid phosphorylation GO:0046834 35 19 1,000 5,38E-03 0,05326455 ! forelimb morphogenesis GO:0035136 32 19 1,000 5,38E-03 0,05304625 ! pigmentation during development GO:0048066 41 19 1,000 5,38E-03 0,05282974 ! plasma membrane fusion GO:0045026 28 19 1,000 5,38E-03 0,05261498 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 5,38E-03 0,05240197 ! regulation of protein complex assembly GO:0043254 117 61 2,000 5,421E-03 0,0525962 ! viral reproductive process GO:0022415 126 62 2,000 5,673E-03 0,05481648 ! regulation of mitosis GO:0007088 105 63 2,000 5,932E-03 0,0570854 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 2,000 5,932E-03 0,05685797 ! protein amino acid deacetylation GO:0006476 29 20 1,000 5,955E-03 0,05685231 ! protein amino acid acetylation GO:0006473 39 20 1,000 5,955E-03 0,05662759 ! transcription from RNA polymerase III promoter GO:0006383 41 20 1,000 5,955E-03 0,05640465 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 5,955E-03 0,05618345 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 5,955E-03 0,05596399 ! DNA duplex unwinding GO:0032508 31 20 1,000 5,955E-03 0,05574623 GO:0032392|DNA geometric change, ! negative regulation of angiogenesis GO:0016525 45 20 1,000 5,955E-03 0,05553016 ! actin filament-based movement GO:0030048 43 20 1,000 5,955E-03 0,05531576 ! embryonic limb morphogenesis GO:0030326 125 65 2,000 6,47E-03 0,05986813 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 2,000 6,47E-03 0,05963875 ! DNA modification GO:0006304 34 21 1,000 6,556E-03 0,06020886 ! positive regulation of locomotion GO:0040017 39 21 1,000 6,556E-03 0,05997993 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! cell projection assembly GO:0030031 120 66 2,000 6,749E-03 0,06150853 ! negative regulation of protein kinase activity GO:0006469 130 67 2,000 7,036E-03 0,06387863 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 7,185E-03 0,06498616 ! regulation of chemotaxis GO:0050920 40 22 1,000 7,185E-03 0,06474276 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 7,185E-03 0,06450119 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 7,185E-03 0,06426141 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 7,185E-03 0,0640234 ! ureteric bud development GO:0001657 43 22 1,000 7,185E-03 0,06378715 ! positive regulation of B cell activation GO:0050871 38 22 1,000 7,185E-03 0,06355264 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 7,185E-03 0,06331985 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 7,185E-03 0,06308875 ! negative regulation of kinase activity GO:0033673 131 68 2,000 7,329E-03 0,06412572 ! viral reproduction GO:0016032 134 68 2,000 7,329E-03 0,06389338 ! negative regulation of cell size GO:0045792 134 69 2,000 7,63E-03 0,06627638 ! urogenital system development GO:0001655 137 69 2,000 7,63E-03 0,06603797 ! positive regulation of DNA replication GO:0045740 43 23 1,000 7,839E-03 0,06760141 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 7,839E-03 0,06735998 ! platelet activation GO:0030168 37 23 1,000 7,839E-03 0,06712026 ! appendage morphogenesis GO:0035107 135 70 2,000 7,938E-03 0,06773008 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 2,000 8,254E-03 0,07017189 GO:0060173|limb development, ! protein import into nucleus, translocation GO:0000060 46 24 1,000 8,519E-03 0,07217385 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 8,519E-03 0,07192061 ! regulation of behavior GO:0050795 43 24 1,000 8,519E-03 0,07166914 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 8,519E-03 0,07141942 ! leukocyte homeostasis GO:0001776 44 24 1,000 8,519E-03 0,07117143 ! protein tetramerization GO:0051262 52 24 1,000 8,519E-03 0,07092517 ! negative regulation of transferase activity GO:0051348 140 72 2,000 8,576E-03 0,07115494 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 9,225E-03 0,07627248 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 9,225E-03 0,07601127 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 9,225E-03 0,07575185 ! somitogenesis GO:0001756 43 25 1,000 9,225E-03 0,07549419 ! neural tube closure GO:0001843 49 25 1,000 9,225E-03 0,07523827 GO:0060606|tube closure, ! eye development GO:0001654 143 74 2,000 9,244E-03 0,07513652 ! regulation of catabolic process GO:0009894 161 76 2,000 9,941E-03 0,08052849 ! initiation of viral infection GO:0019059 57 26 1,000 9,956E-03 0,08038184 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 1,000 9,956E-03 0,080113 ! molting cycle process GO:0022404 50 26 1,000 9,956E-03 0,07984596 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 1,000 9,956E-03 0,07958069 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 9,956E-03 0,07931718 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 9,956E-03 0,0790554 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 9,956E-03 0,07879535 GO:0045936|negative regulation of phosphate metabolic process, ! cellular response to oxidative stress GO:0034599 39 26 1,000 9,956E-03 0,07853701 ! positive regulation of nuclear division GO:0051785 40 26 1,000 9,956E-03 0,07828035 GO:0045840|positive regulation of mitosis, ! blastocyst development GO:0001824 49 26 1,000 9,956E-03 0,07802536 ! blood coagulation GO:0007596 146 78 2,000 0,01066715 0,08332847 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 2,000 0,01066715 0,0830588 ! protein oligomerization GO:0051259 139 78 2,000 0,01066715 0,08279087 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 0,0107116 0,08286852 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 0,0107116 0,08260291 ! protein amino acid acylation GO:0043543 55 27 1,000 0,0107116 0,08233901 ! male gonad development GO:0008584 44 27 1,000 0,0107116 0,08207678 ! primary neural tube formation GO:0014020 51 27 1,000 0,0107116 0,08181622 ! regulation of chromosome organization GO:0033044 42 27 1,000 0,0107116 0,08155731 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 0,0107116 0,08130003 ! muscle cell differentiation GO:0042692 159 80 2,000 0,01142376 0,08643263 ! dendrite development GO:0016358 59 28 1,000 0,0114919 0,08667558 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 0,0114919 0,08640472 ! response to hypoxia GO:0001666 171 81 2,000 0,01181339 0,08854519 ! response to nutrient GO:0007584 125 82 2,000 0,01221058 0,09123809 ! cell fate determination GO:0001709 60 29 1,000 0,01229645 0,0915952 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 0,01229645 0,0913125 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 0,01229645 0,09103154 ! response to oxygen levels GO:0070482 176 83 2,000 0,01261538 0,09310615 ! hemostasis GO:0007599 158 84 2,000 0,0130278 0,0958559 ! acute-phase response GO:0006953 49 30 1,000 0,01312494 0,09627621 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,01312494 0,09598357 ! regulation of B cell activation GO:0050864 50 30 1,000 0,01312494 0,09569271 ! response to heat GO:0009408 50 30 1,000 0,01312494 0,09540361 ! tube morphogenesis GO:0035239 176 86 2,000 0,01387557 0,10055606 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 1,000 0,01397707 0,10098745 ! regulation of protein transport GO:0051223 154 87 2,000 0,01431096 0,1030903 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 2,000 0,01475404 0,10596481 ! negative regulation of response to external stimulus GO:0032102 47 32 1,000 0,01485254 0,10635477 ! spindle organization GO:0007051 46 32 1,000 0,01485254 0,10603918 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01485254 0,10572546 ! hindbrain development GO:0030902 61 32 1,000 0,01485254 0,10541358 ! gene silencing GO:0016458 65 32 1,000 0,01485254 0,10510354 ! ossification GO:0001503 188 90 2,000 0,01566334 0,11051609 ! regulation of cell cycle process GO:0010564 149 90 2,000 0,01566334 0,11019294 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,01575105 0,11048698 ! bone development GO:0060348 189 91 2,000 0,01612958 0,11281329 ! glial cell differentiation GO:0010001 63 34 1,000 0,01667232 0,1162713 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,01667232 0,11593525 ! placenta development GO:0001890 53 34 1,000 0,01667232 0,11560115 ! regulation of muscle development GO:0048634 70 35 1,000 0,01761604 0,12179367 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,01761604 0,1214447 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01761604 0,12109771 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,01761604 0,1207527 ! neural tube formation GO:0001841 67 35 1,000 0,01761604 0,12040966 ! forebrain development GO:0030900 188 95 2,000 0,01807213 0,12317718 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,01858194 0,12629418 ! regulation of proteolysis GO:0030162 72 36 1,000 0,01858194 0,12593842 ! regulation of protein localization GO:0032880 176 97 2,000 0,01909007 0,12901887 ! meiosis I GO:0007127 65 37 1,000 0,01956971 0,13189001 ! sister chromatid segregation GO:0000819 58 37 1,000 0,01956971 0,1315216 ! tissue remodeling GO:0048771 76 37 1,000 0,01956971 0,13115524 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,02057909 0,13753692 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,02057909 0,13715593 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,02057909 0,13677705 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,02160979 0,1432318 ! segmentation GO:0035282 67 39 1,000 0,02160979 0,14283831 ! gliogenesis GO:0042063 88 41 1,000 0,02373402 0,15644944 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,02373402 0,15602198 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,024827 0,16276231 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 1,000 0,024827 0,16232002 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,024827 0,16188013 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 0,024827 0,16144262 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,02594021 0,16822678 ! glucose transport GO:0015758 65 43 1,000 0,02594021 0,16777456 ! positive regulation of response to external stimulus GO:0032103 77 43 1,000 0,02594021 0,16732476 ! neural tube development GO:0021915 77 43 1,000 0,02594021 0,16687737 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 0,02594021 0,16643237 ! hexose transport GO:0008645 67 44 1,000 0,02707336 0,1732407 GO:0015749|monosaccharide transport, ! male sex differentiation GO:0046661 76 44 1,000 0,02707336 0,17278117 ! biopolymer methylation GO:0043414 84 44 1,000 0,02707336 0,17232408 ! branching morphogenesis of a tube GO:0048754 97 45 1,000 0,02822619 0,17918792 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 0,02822619 0,17871637 ! polysaccharide biosynthetic process GO:0000271 70 45 1,000 0,02822619 0,1782473 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02871956 0,18088812 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02871956 0,18041583 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02871956 0,179946 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02871956 0,17947861 ! neuron fate determination GO:0048664 7 5 0,000 0,02871956 0,17901364 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02871956 0,17855107 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02871956 0,17809088 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02871956 0,17763307 ! polyol transport GO:0015791 12 5 0,000 0,02871956 0,1771776 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02871956 0,17672446 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02871956 0,17627363 ! response to superoxide GO:0000303 10 5 0,000 0,02871956 0,1758251 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02871956 0,17537884 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02871956 0,17493484 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02871956 0,17449309 ! female meiosis GO:0007143 7 5 0,000 0,02871956 0,17405356 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02871956 0,17361624 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02871956 0,17318111 ! cobalt ion transport GO:0006824 11 5 0,000 0,02871956 0,17274816 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02871956 0,17231736 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02871956 0,17188871 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02871956 0,17146219 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02871956 0,17103778 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02871956 0,17061547 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02871956 0,17019523 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02871956 0,16977706 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02871956 0,16936094 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02871956 0,16894685 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02871956 0,16853479 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02871956 0,16812473 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02871956 0,16771666 ! negative chemotaxis GO:0050919 14 5 0,000 0,02871956 0,16731057 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02871956 0,16690643 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02871956 0,16650425 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02871956 0,166104 ! behavioral response to pain GO:0048266 9 5 0,000 0,02871956 0,16570567 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02871956 0,16530924 ! Notch receptor processing GO:0007220 8 5 0,000 0,02871956 0,16491471 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02871956 0,16452206 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02871956 0,16413127 ! micturition GO:0060073 9 5 0,000 0,02871956 0,16374233 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02871956 0,16335523 ! copulation GO:0007620 9 5 0,000 0,02871956 0,16296996 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02871956 0,1625865 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02871956 0,16220484 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02871956 0,16182497 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02871956 0,16144688 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02871956 0,16107054 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02871956 0,16069596 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02871956 0,16032312 ! grooming behavior GO:0007625 6 5 0,000 0,02871956 0,159952 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02871956 0,15958259 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02871956 0,15921489 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02871956 0,15884888 ! response to protozoan GO:0001562 10 5 0,000 0,02871956 0,15848455 ! lymph vessel development GO:0001945 10 5 0,000 0,02871956 0,15812188 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02871956 0,15776088 ! endochondral ossification GO:0001958 16 5 0,000 0,02871956 0,15740151 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02871956 0,15704378 ! parathyroid gland development GO:0060017 13 5 0,000 0,02871956 0,15668767 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02871956 0,15633317 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02871956 0,15598028 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02871956 0,15562897 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02871956 0,15527924 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02871956 0,15493108 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02871956 0,15458448 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02871956 0,15423943 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02871956 0,15389591 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02871956 0,15355392 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02871956 0,15321344 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02871956 0,15287448 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02871956 0,15253701 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02871956 0,15220102 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02871956 0,15186651 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02871956 0,15153347 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02871956 0,15120189 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02871956 0,15087175 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02871956 0,15054306 ! histidine catabolic process GO:0006548 6 5 0,000 0,02871956 0,15021579 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02871956 0,14988994 ! microvillus organization GO:0032528 7 5 0,000 0,02871956 0,14956551 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,02871956 0,14924247 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02871956 0,14892083 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02871956 0,14860057 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02871956 0,14828168 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02871956 0,14796416 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02871956 0,147648 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02871956 0,14733318 ! polyol catabolic process GO:0046174 7 5 0,000 0,02871956 0,14701971 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02871956 0,14670757 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02871956 0,14639674 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02871956 0,14608724 ! muscle cell migration GO:0014812 8 5 0,000 0,02871956 0,14577904 ! mitochondrial fission GO:0000266 8 5 0,000 0,02871956 0,14547213 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02871956 0,14516652 ! mRNA transcription GO:0009299 9 5 0,000 0,02871956 0,14486219 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02871956 0,14455913 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02871956 0,14425733 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02871956 0,1439568 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02871956 0,14365751 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02871956 0,14335947 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02871956 0,14306266 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02871956 0,14276707 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02871956 0,14247271 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02871956 0,14217955 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02871956 0,1418876 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02871956 0,14159685 ! forebrain neuron development GO:0021884 13 5 0,000 0,02871956 0,14130729 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02871956 0,1410189 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02871956 0,1407317 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02871956 0,14044566 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02871956 0,14016078 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02871956 0,13987705 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02871956 0,13959447 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02871956 0,13931303 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02871956 0,13903272 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02871956 0,13875354 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02871956 0,13847548 ! basic amino acid transport GO:0015802 11 5 0,000 0,02871956 0,13819853 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02871956 0,13792268 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02871956 0,13764793 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02871956 0,13737428 ! depyrimidination GO:0045008 10 5 0,000 0,02871956 0,13710171 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02871956 0,13683022 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02871956 0,13655981 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02871956 0,13629046 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02871956 0,13602217 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02871956 0,13575494 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02871956 0,13548875 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02871956 0,13522361 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02871956 0,1349595 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02871956 0,13469642 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02871956 0,13443436 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02871956 0,13417333 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02871956 0,1339133 ! response to arsenic GO:0046685 10 5 0,000 0,02871956 0,13365428 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02871956 0,13339626 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02871956 0,13313924 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02871956 0,1328832 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02871956 0,13262814 ! response to cadmium ion GO:0046686 7 5 0,000 0,02871956 0,13237407 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02871956 0,13212096 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02871956 0,13186882 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02871956 0,13161764 ! decidualization GO:0046697 11 5 0,000 0,02871956 0,13136742 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02871956 0,13111815 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02871956 0,13086982 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02871956 0,13062243 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02871956 0,13037597 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02871956 0,13013044 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02871956 0,12988583 ! neural tube patterning GO:0021532 7 5 0,000 0,02871956 0,12964215 ! embryonic cleavage GO:0040016 6 5 0,000 0,02871956 0,12939937 ! peroxisome fission GO:0016559 5 5 0,000 0,02871956 0,1291575 ! histone demethylation GO:0016577 10 5 0,000 0,02871956 0,12891654 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02871956 0,12867647 ! mitotic recombination GO:0006312 9 5 0,000 0,02871956 0,12843729 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02871956 0,128199 ! metaphase plate congression GO:0051310 7 5 0,000 0,02871956 0,1279616 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02871956 0,12772507 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02871956 0,12748942 ! enteric nervous system development GO:0048484 8 5 0,000 0,02871956 0,12725463 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02871956 0,1270207 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02871956 0,12678764 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02871956 0,12655543 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02871956 0,12632406 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02871956 0,12609355 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02871956 0,12586387 ! plasminogen activation GO:0031639 5 5 0,000 0,02871956 0,12563502 ! B cell homeostasis GO:0001782 13 5 0,000 0,02871956 0,12540701 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02871956 0,12517982 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02871956 0,12495346 ! metaphase GO:0051323 8 5 0,000 0,02871956 0,12472791 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02871956 0,12450318 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02871956 0,12427925 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02871956 0,12405613 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02871956 0,12383381 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02871956 0,12361228 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02871956 0,12339154 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02871956 0,12317159 ! response to redox state GO:0051775 5 5 0,000 0,02871956 0,12295243 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02871956 0,12273404 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02871956 0,12251642 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02871956 0,12229958 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02871956 0,1220835 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02871956 0,12186819 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02871956 0,12165363 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02871956 0,12143983 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02871956 0,12122678 ! striatum development GO:0021756 9 5 0,000 0,02871956 0,12101447 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02871956 0,12080291 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02871956 0,12059208 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02871956 0,12038199 ! glial cell migration GO:0008347 11 5 0,000 0,02871956 0,12017263 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02871956 0,119964 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02871956 0,11975609 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02871956 0,1195489 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02871956 0,11934242 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02871956 0,11913666 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02871956 0,11893161 ! neuroprotection GO:0043526 6 5 0,000 0,02871956 0,11872726 ! neural plate development GO:0001840 8 5 0,000 0,02871956 0,11852361 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02871956 0,11832066 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02871956 0,1181184 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02871956 0,11791683 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02871956 0,11771595 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02871956 0,11751575 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02871956 0,11731624 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02871956 0,1171174 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02871956 0,11691923 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02871956 0,11672173 ! spindle assembly GO:0051225 6 5 0,000 0,02871956 0,1165249 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02871956 0,11632873 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02871956 0,11613322 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02871956 0,11593836 ! drug metabolic process GO:0017144 6 5 0,000 0,02871956 0,11574416 ! stem cell division GO:0017145 11 5 0,000 0,02871956 0,11555061 GO:0048103|somatic stem cell division, ! organ regeneration GO:0031100 7 5 0,000 0,02871956 0,1153577 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02871956 0,11516544 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02871956 0,11497382 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02871956 0,11478283 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,02939845 0,11730126 ! pigmentation GO:0043473 100 46 1,000 0,02939845 0,11710706 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,03058986 0,12165156 ! methylation GO:0032259 90 47 1,000 0,03058986 0,12145081 ! protein homooligomerization GO:0051260 76 47 1,000 0,03058986 0,12125073 ! Notch signaling pathway GO:0007219 96 48 1,000 0,03180016 0,12584077 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,03180016 0,12563413 ! regulation of inflammatory response GO:0050727 75 48 1,000 0,03180016 0,12542817 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,03180016 0,12522289 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,03302911 0,12984972 ! response to temperature stimulus GO:0009266 76 49 1,000 0,03302911 0,12963789 ! DNA-dependent DNA replication GO:0006261 74 49 1,000 0,03302911 0,12942676 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03436429 0,13443981 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03436429 0,13422156 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03436429 0,13400402 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03436429 0,13378719 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03436429 0,13357105 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03436429 0,13335561 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03436429 0,13314087 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03436429 0,13292682 ! sleep GO:0030431 13 6 0,000 0,03436429 0,13271345 ! response to oxygen radical GO:0000305 11 6 0,000 0,03436429 0,13250077 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03436429 0,13228877 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03436429 0,13207745 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03436429 0,1318668 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03436429 0,13165682 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03436429 0,13144751 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03436429 0,13123886 ! forebrain regionalization GO:0021871 8 6 0,000 0,03436429 0,13103087 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03436429 0,13082355 ! male meiosis GO:0007140 7 6 0,000 0,03436429 0,13061687 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03436429 0,13041085 ! response to zinc ion GO:0010043 9 6 0,000 0,03436429 0,13020548 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03436429 0,13000076 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03436429 0,12979667 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03436429 0,12959323 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03436429 0,12939042 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03436429 0,12918825 ! malate metabolic process GO:0006108 11 6 0,000 0,03436429 0,12898671 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03436429 0,1287858 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03436429 0,12858551 ! protein refolding GO:0042026 15 6 0,000 0,03436429 0,12838584 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03436429 0,12818679 ! opsonization GO:0008228 8 6 0,000 0,03436429 0,12798836 ! mating behavior GO:0007617 7 6 0,000 0,03436429 0,12779054 ! neuron remodeling GO:0016322 15 6 0,000 0,03436429 0,12759334 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03436429 0,12739674 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03436429 0,12720074 ! equilibrioception GO:0050957 14 6 0,000 0,03436429 0,12700535 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03436429 0,12681055 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03436429 0,12661636 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03436429 0,12642275 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03436429 0,12622974 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03436429 0,12603732 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03436429 0,12584548 ! toxin metabolic process GO:0009404 11 6 0,000 0,03436429 0,12565423 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03436429 0,12546355 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03436429 0,12527346 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03436429 0,12508394 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03436429 0,12489499 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03436429 0,12470661 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03436429 0,1245188 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03436429 0,12433155 ! thymic T cell selection GO:0045061 12 6 0,000 0,03436429 0,12414487 ! protein lipoylation GO:0009249 10 6 0,000 0,03436429 0,12395874 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03436429 0,12377318 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03436429 0,12358816 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03436429 0,1234037 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03436429 0,12321979 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03436429 0,12303643 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03436429 0,12285361 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03436429 0,12267134 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03436429 0,1224896 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03436429 0,1223084 ! hyperosmotic response GO:0006972 9 6 0,000 0,03436429 0,12212774 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03436429 0,12194761 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03436429 0,12176801 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03436429 0,12158894 ! urea metabolic process GO:0019627 7 6 0,000 0,03436429 0,1214104 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03436429 0,12123238 ! neutrophil activation GO:0042119 8 6 0,000 0,03436429 0,12105488 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03436429 0,1208779 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03436429 0,12070143 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03436429 0,12052548 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03436429 0,12035005 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03436429 0,12017512 ! neuron apoptosis GO:0051402 9 6 0,000 0,03436429 0,1200007 ! nucleoside salvage GO:0043174 9 6 0,000 0,03436429 0,11982678 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03436429 0,11965337 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03436429 0,11948046 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03436429 0,11930805 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,03436429 0,11913614 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03436429 0,11896472 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03436429 0,11879379 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03436429 0,11862336 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03436429 0,11845341 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03436429 0,11828395 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03436429 0,11811497 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03436429 0,11794648 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03436429 0,11777846 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03436429 0,11761093 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03436429 0,11744387 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03436429 0,11727728 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03436429 0,11711116 ! neural nucleus development GO:0048857 14 6 0,000 0,03436429 0,11694552 ! response to UV-C GO:0010225 11 6 0,000 0,03436429 0,11678034 ! astrocyte development GO:0014002 15 6 0,000 0,03436429 0,11661563 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03436429 0,11645138 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03436429 0,1162876 ! interaction with symbiont GO:0051702 13 6 0,000 0,03436429 0,11612427 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03436429 0,1159614 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03436429 0,11579899 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03436429 0,11563704 ! response to copper ion GO:0046688 10 6 0,000 0,03436429 0,11547553 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03436429 0,11531448 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03436429 0,11515387 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03436429 0,11499372 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03436429 0,114834 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03436429 0,11467473 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03436429 0,1145159 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03436429 0,11435751 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03436429 0,11419956 ! Schwann cell development GO:0014044 15 6 0,000 0,03436429 0,11404204 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03436429 0,11388496 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03436429 0,11372831 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03436429 0,11357209 ! subpallium development GO:0021544 10 6 0,000 0,03436429 0,1134163 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03436429 0,11326093 ! histone ubiquitination GO:0016574 8 6 0,000 0,03436429 0,11310599 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03436429 0,11295148 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03436429 0,11279738 ! G2 phase GO:0051319 16 6 0,000 0,03436429 0,11264371 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03436429 0,11249045 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03436429 0,11233761 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03436429 0,11218518 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03436429 0,11203317 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03436429 0,11188157 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03436429 0,11173038 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03436429 0,1115796 ! receptor internalization GO:0031623 10 6 0,000 0,03436429 0,11142922 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03436429 0,11127925 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03436429 0,11112968 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03436429 0,11098051 ! protein deubiquitination GO:0016579 14 6 0,000 0,03436429 0,11083174 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03436429 0,11068337 ! protein destabilization GO:0031648 9 6 0,000 0,03436429 0,1105354 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03436429 0,11038783 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03436429 0,11024064 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03436429 0,11009385 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03436429 0,10994745 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03436429 0,10980144 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03436429 0,10965581 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03436429 0,10951057 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03436429 0,10936572 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03436429 0,10922124 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03436429 0,10907715 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03436429 0,10893344 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03436429 0,10879011 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03436429 0,10864715 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03436429 0,10850457 ! catecholamine transport GO:0051937 9 6 0,000 0,03436429 0,10836236 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03436429 0,10822052 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03436429 0,10807906 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03436429 0,10793796 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03436429 0,10779724 ! maternal placenta development GO:0001893 12 6 0,000 0,03436429 0,10765688 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03436429 0,10751688 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03436429 0,10737725 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,03436429 0,10723798 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03436429 0,10709907 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03436429 0,10696052 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03436429 0,10682233 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03436429 0,10668449 ! viral infectious cycle GO:0019058 99 51 1,000 0,0355419 0,1101982 ! chromatin remodeling GO:0006338 109 51 1,000 0,0355419 0,11005638 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,0355419 0,10991492 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! membrane fusion GO:0006944 110 52 1,000 0,03682524 0,11373753 ! morphogenesis of a branching structure GO:0001763 111 52 1,000 0,03682524 0,11359171 ! amino acid activation GO:0043038 92 52 1,000 0,03682524 0,11344626 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 1,000 0,03682524 0,11330119 ! regulation of translational initiation GO:0006446 82 53 1,000 0,03812622 0,11715413 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,03944459 0,12105061 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,03944459 0,12089641 ! tRNA transcription GO:0009304 14 7 0,000 0,0399764 0,12237051 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,0399764 0,12221502 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,0399764 0,12205992 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,0399764 0,12190522 ! regulation of helicase activity GO:0051095 15 7 0,000 0,0399764 0,12175091 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,0399764 0,12159699 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,0399764 0,12144346 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,0399764 0,12129031 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,0399764 0,12113755 ! prostate gland development GO:0030850 13 7 0,000 0,0399764 0,12098518 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,0399764 0,12083319 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0399764 0,12068158 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,0399764 0,12053035 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,0399764 0,1203795 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0399764 0,12022902 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,0399764 0,12007892 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,0399764 0,1199292 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,0399764 0,11977985 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,0399764 0,11963087 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,0399764 0,11948226 ! glycolipid transport GO:0046836 10 7 0,000 0,0399764 0,11933402 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,0399764 0,11918614 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,0399764 0,11903864 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,0399764 0,11889149 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,0399764 0,11874471 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,0399764 0,1185983 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,0399764 0,11845224 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,0399764 0,11830654 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,0399764 0,1181612 ! pericardium development GO:0060039 14 7 0,000 0,0399764 0,11801622 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,0399764 0,11787159 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,0399764 0,11772732 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,0399764 0,1175834 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0399764 0,11743983 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,0399764 0,11729661 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,0399764 0,11715374 ! lipoprotein transport GO:0042953 14 7 0,000 0,0399764 0,11701121 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0399764 0,11686904 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0399764 0,11672721 ! rhythmic behavior GO:0007622 15 7 0,000 0,0399764 0,11658572 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,0399764 0,11644457 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,0399764 0,11630377 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,0399764 0,11616331 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,0399764 0,11602318 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,0399764 0,1158834 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,0399764 0,11574394 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,0399764 0,11560483 ! mechanosensory behavior GO:0007638 14 7 0,000 0,0399764 0,11546605 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,0399764 0,1153276 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0399764 0,11518948 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,0399764 0,1150517 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0399764 0,11491424 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0399764 0,11477711 ! spinal cord patterning GO:0021511 13 7 0,000 0,0399764 0,11464031 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,0399764 0,11450383 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,0399764 0,11436768 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,0399764 0,11423185 ! adrenal gland development GO:0030325 17 7 0,000 0,0399764 0,11409634 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,0399764 0,11396116 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,0399764 0,11382629 ! ovulation GO:0030728 9 7 0,000 0,0399764 0,11369175 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,0399764 0,11355752 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,0399764 0,11342361 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,0399764 0,11329001 ! microtubule nucleation GO:0007020 20 7 0,000 0,0399764 0,11315673 ! proline biosynthetic process GO:0006561 10 7 0,000 0,0399764 0,11302376 ! thyroid hormone generation GO:0006590 13 7 0,000 0,0399764 0,1128911 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,0399764 0,11275876 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,0399764 0,11262672 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,0399764 0,11249499 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0399764 0,11236357 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0399764 0,11223246 ! galactose metabolic process GO:0006012 13 7 0,000 0,0399764 0,11210165 ! vesicle fusion GO:0006906 17 7 0,000 0,0399764 0,11197115 ! response to dietary excess GO:0002021 8 7 0,000 0,0399764 0,11184095 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,0399764 0,11171105 ! intracellular pH reduction GO:0051452 11 7 0,000 0,0399764 0,11158146 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,0399764 0,11145216 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,0399764 0,11132317 ! organ growth GO:0035265 15 7 0,000 0,0399764 0,11119447 ! purine salvage GO:0043101 10 7 0,000 0,0399764 0,11106607 ! nucleoside transport GO:0015858 8 7 0,000 0,0399764 0,11093797 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,0399764 0,11081016 ! parturition GO:0007567 14 7 0,000 0,0399764 0,11068264 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,0399764 0,11055542 ! rRNA modification GO:0000154 14 7 0,000 0,0399764 0,11042849 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,0399764 0,11030186 ! spindle checkpoint GO:0031577 15 7 0,000 0,0399764 0,11017551 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,0399764 0,11004945 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,0399764 0,10992368 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0399764 0,10979819 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,0399764 0,109673 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,0399764 0,10954808 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,0399764 0,10942346 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,0399764 0,10929911 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,0399764 0,10917505 ! fibrinolysis GO:0042730 10 7 0,000 0,0399764 0,10905127 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,0399764 0,10892777 ! eating behavior GO:0042755 7 7 0,000 0,0399764 0,10880455 ! B cell lineage commitment GO:0002326 21 7 0,000 0,0399764 0,1086816 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,0399764 0,10855894 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,0399764 0,10843655 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,0399764 0,10831443 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,0399764 0,1081926 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,0399764 0,10807103 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,0399764 0,10794974 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,0399764 0,10782872 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,0399764 0,10770797 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,0399764 0,10758749 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,0399764 0,10746728 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,0399764 0,10734734 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,0399764 0,10722767 ! regulation of meiosis GO:0040020 12 7 0,000 0,0399764 0,10710826 GO:0051445|regulation of meiotic cell cycle, ! T cell lineage commitment GO:0002360 16 7 0,000 0,0399764 0,10698912 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,0399764 0,10687024 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,0399764 0,10675163 ! oxygen homeostasis GO:0032364 12 7 0,000 0,0399764 0,10663328 ! transcription termination GO:0006353 13 7 0,000 0,0399764 0,10651519 ! response to tumor cell GO:0002347 13 7 0,000 0,0399764 0,10639737 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,0399764 0,1062798 ! anaphase GO:0051322 17 7 0,000 0,0399764 0,10616249 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,0399764 0,10604544 ! axonal fasciculation GO:0007413 18 7 0,000 0,0399764 0,10592865 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,0399764 0,10581212 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,0399764 0,10569584 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,0399764 0,10557982 ! diuresis GO:0030146 12 7 0,000 0,0399764 0,10546406 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,0399764 0,10534854 ! thiamin metabolic process GO:0006772 7 7 0,000 0,0399764 0,10523328 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0399764 0,10511827 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,0399764 0,10500351 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,0399764 0,10488901 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,0399764 0,10477475 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,0399764 0,10466074 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0399764 0,10454698 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0399764 0,10443346 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,0399764 0,10432019 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,0399764 0,10420717 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,0399764 0,10409439 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,0399764 0,10398186 ! lymph node development GO:0048535 10 7 0,000 0,0399764 0,10386957 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,0399764 0,10375752 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0399764 0,10364571 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,0399764 0,10353414 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,0399764 0,10342282 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,0399764 0,10331173 ! adult feeding behavior GO:0008343 9 7 0,000 0,0399764 0,10320088 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,0399764 0,10309027 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,0399764 0,10297989 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,0399764 0,10286975 ! muscle adaptation GO:0043500 14 7 0,000 0,0399764 0,10275985 ! embryonic heart tube development GO:0035050 10 7 0,000 0,0399764 0,10265018 ! retina homeostasis GO:0001895 12 7 0,000 0,0399764 0,10254074 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,0399764 0,10243154 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,0399764 0,10232257 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,0399764 0,10221383 ! protein prenylation GO:0018342 18 7 0,000 0,0399764 0,10210533 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,0399764 0,10199705 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,0399764 0,101889 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0399764 0,10178118 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,0407801 0,10371768 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,0407801 0,10360815 ! heart morphogenesis GO:0003007 97 55 1,000 0,0407801 0,10349886 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,0407801 0,1033898 ! regulation of DNA replication GO:0006275 101 56 1,000 0,04213252 0,10670614 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,04213252 0,10659394 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,0435016 0,10994206 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,0435016 0,1098267 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,04488711 0,11320584 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,04488711 0,1130873 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04555608 0,11465264 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04555608 0,11453284 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04555608 0,11441328 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04555608 0,11429398 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04555608 0,11417492 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04555608 0,11405611 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04555608 0,11393755 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04555608 0,11381924 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04555608 0,11370117 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04555608 0,11358334 ! meiotic prophase I GO:0007128 13 8 0,000 0,04555608 0,11346576 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04555608 0,11334842 ! oligopeptide transport GO:0006857 15 8 0,000 0,04555608 0,11323133 ! UTP metabolic process GO:0046051 8 8 0,000 0,04555608 0,11311447 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04555608 0,11299786 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04555608 0,11288149 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04555608 0,11276536 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04555608 0,11264946 ! succinate metabolic process GO:0006105 14 8 0,000 0,04555608 0,1125338 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04555608 0,11241839 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04555608 0,1123032 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04555608 0,11218826 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04555608 0,11207354 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04555608 0,11195907 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04555608 0,11184482 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04555608 0,11173081 ! reflex GO:0060004 16 8 0,000 0,04555608 0,11161703 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04555608 0,11150348 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04555608 0,11139017 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04555608 0,11127708 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04555608 0,11116422 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04555608 0,1110516 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04555608 0,1109392 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04555608 0,11082702 ! pigment granule organization GO:0048753 16 8 0,000 0,04555608 0,11071508 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04555608 0,11060336 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04555608 0,11049186 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04555608 0,11038059 ! histidine metabolic process GO:0006547 16 8 0,000 0,04555608 0,11026954 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04555608 0,11015872 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04555608 0,11004812 ! glycine catabolic process GO:0006546 13 8 0,000 0,04555608 0,10993774 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04555608 0,10982758 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04555608 0,10971764 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04555608 0,10960793 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04555608 0,10949843 ! melanin metabolic process GO:0006582 15 8 0,000 0,04555608 0,10938915 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04555608 0,10928009 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04555608 0,10917124 ! macrophage activation GO:0042116 12 8 0,000 0,04555608 0,10906261 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04555608 0,1089542 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04555608 0,108846 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04555608 0,10873802 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04555608 0,10863025 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04555608 0,1085227 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04555608 0,10841536 ! osteoblast development GO:0002076 16 8 0,000 0,04555608 0,10830823 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04555608 0,10820131 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04555608 0,1080946 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04555608 0,1079881 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04555608 0,10788182 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04555608 0,10777574 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04555608 0,10766987 ! response to UV-B GO:0010224 16 8 0,000 0,04555608 0,10756421 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04555608 0,10745875 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04555608 0,1073535 ! intermediate filament organization GO:0045109 12 8 0,000 0,04555608 0,10724846 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04555608 0,10714362 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04555608 0,10703899 ! cellular extravasation GO:0045123 12 8 0,000 0,04555608 0,10693456 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04555608 0,10683034 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04555608 0,10672631 ! response to antibiotic GO:0046677 11 8 0,000 0,04555608 0,1066225 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04555608 0,10651888 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04555608 0,10641546 ! DNA topological change GO:0006265 12 8 0,000 0,04555608 0,10631225 ! response to tropane GO:0014073 15 8 0,000 0,04555608 0,10620923 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04555608 0,10610641 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,04555608 0,1060038 ! melanosome transport GO:0032402 13 8 0,000 0,04555608 0,10590138 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04555608 0,10579916 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04555608 0,10569713 ! mast cell activation GO:0045576 14 8 0,000 0,04555608 0,1055953 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04555608 0,10549367 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04555608 0,10539224 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04555608 0,10529099 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04555608 0,10518995 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04555608 0,10508909 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04555608 0,10498843 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04555608 0,10488797 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04555608 0,10478769 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04555608 0,10468761 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04555608 0,10458772 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04555608 0,10448801 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04555608 0,1043885 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04555608 0,10428918 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04555608 0,10419004 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04555608 0,1040911 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04555608 0,10399234 ! hormone catabolic process GO:0042447 17 8 0,000 0,04555608 0,10389377 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04555608 0,10379538 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04555608 0,10369719 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04555608 0,10359917 ! ATP catabolic process GO:0006200 11 8 0,000 0,04555608 0,10350135 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04555608 0,1034037 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04555608 0,10330624 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04555608 0,10320897 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04555608 0,10311188 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04555608 0,10301497 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04555608 0,10291824 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04555608 0,10282169 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04555608 0,10272533 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04555608 0,10262914 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04555608 0,10253314 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04555608 0,10243731 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04555608 0,10234167 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04555608 0,1022462 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04555608 0,10215091 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04555608 0,1020558 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04555608 0,10196086 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,04628881 0,10350453 ! cytokine-mediated signaling pathway GO:0019221 97 59 1,000 0,04628881 0,10340842 ! camera-type eye development GO:0043010 116 60 1,000 0,04770647 0,10647659 ! negative regulation of response to stimulus GO:0048585 100 60 1,000 0,04770647 0,10637791 ! mesoderm development GO:0007498 119 61 1,000 0,04913986 0,10947269 ! gonad development GO:0008406 98 62 1,000 0,05058876 0,11259625 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,05058876 0,11249219 ! axon extension GO:0048675 15 9 0,000 0,05110351 0,1135319 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05110351 0,11342717 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05110351 0,11332263 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05110351 0,11321828 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05110351 0,11311412 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05110351 0,11301016 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05110351 0,11290638 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05110351 0,1128028 ! phosphate transport GO:0006817 19 9 0,000 0,05110351 0,11269941 ! reproductive behavior GO:0019098 19 9 0,000 0,05110351 0,1125962 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05110351 0,11249319 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05110351 0,11239036 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05110351 0,11228772 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05110351 0,11218527 ! GTP metabolic process GO:0046039 9 9 0,000 0,05110351 0,112083 ! RNA methylation GO:0001510 15 9 0,000 0,05110351 0,11198092 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05110351 0,11187903 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05110351 0,11177732 ! artery development GO:0060840 24 9 0,000 0,05110351 0,1116758 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05110351 0,11157446 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05110351 0,1114733 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05110351 0,11137233 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05110351 0,11127154 ! chemosensory behavior GO:0007635 20 9 0,000 0,05110351 0,11117093 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,05110351 0,11107051 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05110351 0,11097026 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05110351 0,1108702 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05110351 0,11077032 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05110351 0,11067061 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05110351 0,11057109 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05110351 0,11047174 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05110351 0,11037258 ! protein targeting to ER GO:0045047 22 9 0,000 0,05110351 0,11027359 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05110351 0,11017478 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05110351 0,11007614 ! T cell selection GO:0045058 23 9 0,000 0,05110351 0,10997768 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05110351 0,1098794 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05110351 0,1097813 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05110351 0,10968336 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05110351 0,10958561 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05110351 0,10948802 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05110351 0,10939062 ! mannose metabolic process GO:0006013 13 9 0,000 0,05110351 0,10929338 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05110351 0,10919632 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05110351 0,10909942 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05110351 0,10900271 ! receptor clustering GO:0043113 18 9 0,000 0,05110351 0,10890616 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05110351 0,10880978 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05110351 0,10871357 ! ruffle organization GO:0031529 15 9 0,000 0,05110351 0,10861754 ! retinol metabolic process GO:0042572 18 9 0,000 0,05110351 0,10852167 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05110351 0,10842597 ! behavioral fear response GO:0001662 22 9 0,000 0,05110351 0,10833044 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05110351 0,10823508 GO:0007351|tripartite regional subdivision, ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05110351 0,10813989 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,05110351 0,10804486 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,05110351 0,10795 ! segment specification GO:0007379 13 9 0,000 0,05110351 0,10785531 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05110351 0,10776078 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05110351 0,10766642 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05110351 0,10757222 ! response to amine stimulus GO:0014075 13 9 0,000 0,05110351 0,10747819 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05110351 0,10738432 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05110351 0,10729062 ! erythrocyte development GO:0048821 15 9 0,000 0,05110351 0,10719708 ! gas homeostasis GO:0033483 16 9 0,000 0,05110351 0,1071037 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05110351 0,10701049 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,05110351 0,10691744 ! renal water homeostasis GO:0003091 14 9 0,000 0,05110351 0,10682455 ! postreplication repair GO:0006301 22 9 0,000 0,05110351 0,10673182 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05110351 0,10663925 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05110351 0,10654684 ! icosanoid secretion GO:0032309 15 9 0,000 0,05110351 0,10645459 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,05110351 0,1063625 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05110351 0,10627057 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05110351 0,1061788 ! regulation of cell division GO:0051302 15 9 0,000 0,05110351 0,10608719 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05110351 0,10599573 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05110351 0,10590444 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05110351 0,1058133 ! sterol catabolic process GO:0016127 11 9 0,000 0,05110351 0,10572231 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05110351 0,10563149 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05110351 0,10554082 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05110351 0,1054503 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05110351 0,10535994 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,05110351 0,10526974 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,05110351 0,10517968 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05110351 0,10508979 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05110351 0,10500004 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05110351 0,10491045 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05110351 0,10482102 ! purine base metabolic process GO:0006144 21 9 0,000 0,05110351 0,10473173 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05110351 0,1046426 ! pigment granule transport GO:0051904 17 9 0,000 0,05110351 0,10455362 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05110351 0,10446478 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,05110351 0,1043761 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05110351 0,10428758 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05110351 0,1041992 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05110351 0,10411097 ! mitochondrion localization GO:0051646 15 9 0,000 0,05110351 0,10402289 ! cell redox homeostasis GO:0045454 102 64 1,000 0,05353215 0,10887434 ! developmental maturation GO:0021700 116 66 1,000 0,05653486 0,11488418 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,05661889 0,11495784 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05661889 0,11486091 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05661889 0,11476415 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05661889 0,11466754 ! synapsis GO:0007129 13 10 0,000 0,05661889 0,1145711 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05661889 0,11447482 ! N-glycan processing GO:0006491 20 10 0,000 0,05661889 0,11437871 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05661889 0,11428275 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,05661889 0,11418696 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,05661889 0,11409132 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05661889 0,11399585 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05661889 0,11390054 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05661889 0,11380538 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05661889 0,11371039 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05661889 0,11361555 ! androgen metabolic process GO:0008209 17 10 0,000 0,05661889 0,11352087 ! phospholipid efflux GO:0033700 16 10 0,000 0,05661889 0,11342635 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05661889 0,11333198 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05661889 0,11323777 ! pathogenesis GO:0009405 13 10 0,000 0,05661889 0,11314372 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05661889 0,11304983 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05661889 0,11295609 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05661889 0,1128625 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,05661889 0,11276907 ! endoderm development GO:0007492 16 10 0,000 0,05661889 0,1126758 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05661889 0,11258268 ! arginine catabolic process GO:0006527 13 10 0,000 0,05661889 0,11248971 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05661889 0,1123969 ! proline metabolic process GO:0006560 13 10 0,000 0,05661889 0,11230424 ! L-serine metabolic process GO:0006563 18 10 0,000 0,05661889 0,11221173 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05661889 0,11211938 ! V(D)J recombination GO:0033151 28 10 0,000 0,05661889 0,11202717 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05661889 0,11193512 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05661889 0,11184322 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05661889 0,11175147 ! B cell proliferation GO:0042100 18 10 0,000 0,05661889 0,11165987 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05661889 0,11156842 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05661889 0,11147712 ! multicellular organism growth GO:0035264 18 10 0,000 0,05661889 0,11138597 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05661889 0,11129497 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05661889 0,11120412 ! epithelial cell development GO:0002064 20 10 0,000 0,05661889 0,11111341 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05661889 0,11102285 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05661889 0,11093244 ! macroautophagy GO:0016236 17 10 0,000 0,05661889 0,11084218 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05661889 0,11075207 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05661889 0,1106621 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05661889 0,11057227 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05661889 0,1104826 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,05661889 0,11039306 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05661889 0,11030368 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05661889 0,11021443 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05661889 0,11012534 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,05661889 0,11003638 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05661889 0,10994757 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05661889 0,1098589 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,05661889 0,10977038 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05661889 0,109682 ! response to dsRNA GO:0043331 20 10 0,000 0,05661889 0,10959376 ! DNA ligation GO:0006266 19 10 0,000 0,05661889 0,10950566 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05661889 0,1094177 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05661889 0,10932989 ! melanosome localization GO:0032400 16 10 0,000 0,05661889 0,10924221 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05661889 0,10915468 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05661889 0,10906729 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05661889 0,10898003 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05661889 0,10889292 ! mRNA cleavage GO:0006379 17 10 0,000 0,05661889 0,10880594 ! protein sumoylation GO:0016925 15 10 0,000 0,05661889 0,10871911 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05661889 0,10863241 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05661889 0,10854585 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05661889 0,10845943 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05661889 0,10837314 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05661889 0,108287 ! salivary gland development GO:0007431 27 10 0,000 0,05661889 0,10820099 ! prophase GO:0051324 15 10 0,000 0,05661889 0,10811511 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05661889 0,10802937 ! apical protein localization GO:0045176 15 10 0,000 0,05661889 0,10794377 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05661889 0,10785831 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05661889 0,10777298 ! midbrain development GO:0030901 13 10 0,000 0,05661889 0,10768778 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05661889 0,10760272 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05661889 0,10751779 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05661889 0,107433 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05661889 0,10734834 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05661889 0,10726381 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05661889 0,10717942 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05661889 0,10709516 ! detection of calcium ion GO:0005513 23 10 0,000 0,05661889 0,10701103 ! oocyte development GO:0048599 17 10 0,000 0,05661889 0,10692703 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05661889 0,10684317 ! blastocyst formation GO:0001825 17 10 0,000 0,05661889 0,10675944 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05661889 0,10667584 ! activation of innate immune response GO:0002218 12 10 0,000 0,05661889 0,10659236 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05661889 0,10650902 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05661889 0,10642581 ! response to nicotine GO:0035094 20 10 0,000 0,05661889 0,10634273 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05661889 0,10625978 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05661889 0,10617696 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,05805791 0,10879076 ! activation of MAPK activity GO:0000187 115 67 1,000 0,05805791 0,1087061 ! chromosome segregation GO:0007059 113 67 1,000 0,05805791 0,10862157 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,05805791 0,10853717 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,05805791 0,1084529 ! adaptive immune response GO:0002250 119 67 1,000 0,05805791 0,10836876 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of lipase activity GO:0060191 130 68 1,000 0,05959514 0,11115186 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,05959514 0,11106577 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,06114633 0,11386847 ! respiratory burst GO:0045730 17 11 0,000 0,06210239 0,11555943 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06210239 0,11547012 ! neuron fate specification GO:0048665 17 11 0,000 0,06210239 0,11538096 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06210239 0,11529193 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06210239 0,11520304 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06210239 0,11511428 ! thyroid gland development GO:0030878 26 11 0,000 0,06210239 0,11502567 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06210239 0,11493718 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06210239 0,11484884 ! response to pain GO:0048265 24 11 0,000 0,06210239 0,11476063 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,06210239 0,11467256 ! T cell proliferation GO:0042098 26 11 0,000 0,06210239 0,11458462 ! bone resorption GO:0045453 16 11 0,000 0,06210239 0,11449681 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06210239 0,11440914 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06210239 0,11432161 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06210239 0,1142342 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06210239 0,11414694 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06210239 0,1140598 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06210239 0,1139728 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06210239 0,11388593 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06210239 0,11379919 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06210239 0,11371259 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,06210239 0,11362611 ! lipid digestion GO:0044241 18 11 0,000 0,06210239 0,11353977 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06210239 0,11345356 ! UV protection GO:0009650 19 11 0,000 0,06210239 0,11336748 ! adult heart development GO:0007512 14 11 0,000 0,06210239 0,11328153 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,06210239 0,11319571 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06210239 0,11311002 ! temperature homeostasis GO:0001659 17 11 0,000 0,06210239 0,11302446 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06210239 0,11293903 ! negative regulation of ossification GO:0030279 26 11 0,000 0,06210239 0,11285373 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,06210239 0,11276856 ! regulation of organ growth GO:0046620 13 11 0,000 0,06210239 0,11268351 ! pigment granule localization GO:0051875 20 11 0,000 0,06210239 0,1125986 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06210239 0,11251381 ! vasoconstriction GO:0042310 18 11 0,000 0,06210239 0,11242915 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06210239 0,11234462 ! embryonic axis specification GO:0000578 18 11 0,000 0,06210239 0,11226021 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06210239 0,11217593 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06210239 0,11209178 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06210239 0,11200775 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06210239 0,11192385 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06210239 0,11184007 ! zymogen activation GO:0031638 15 11 0,000 0,06210239 0,11175642 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06210239 0,1116729 ! neuroblast proliferation GO:0007405 24 11 0,000 0,06210239 0,1115895 ! nucleosome positioning GO:0016584 15 11 0,000 0,06210239 0,11150622 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06210239 0,11142307 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06210239 0,11134004 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06210239 0,11125714 ! acid secretion GO:0046717 18 11 0,000 0,06210239 0,11117436 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06210239 0,1110917 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06210239 0,11100917 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06210239 0,11092676 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06210239 0,11084447 ! oocyte differentiation GO:0009994 18 11 0,000 0,06210239 0,1107623 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06210239 0,11068025 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,06210239 0,11059833 ! cholesterol efflux GO:0033344 19 11 0,000 0,06210239 0,11051652 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06210239 0,11043484 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06210239 0,11035328 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,06210239 0,11027184 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,06210239 0,11019052 ! embryonic gut development GO:0048566 15 11 0,000 0,06210239 0,11010931 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06210239 0,11002823 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06210239 0,10994727 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06210239 0,10986643 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06210239 0,1097857 ! defense response to fungus GO:0050832 13 11 0,000 0,06210239 0,1097051 ! developmental induction GO:0031128 19 11 0,000 0,06210239 0,10962461 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,06210239 0,10954424 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06210239 0,10946398 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06210239 0,10938385 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06210239 0,10930383 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06210239 0,10922393 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06210239 0,10914415 ! reproductive structure development GO:0048608 113 71 1,000 0,06428974 0,11290593 ! acute inflammatory response GO:0002526 113 72 1,000 0,06588155 0,11561708 ! regulation of caspase activity GO:0043281 122 72 1,000 0,06588155 0,11553281 ! carbohydrate transport GO:0008643 110 72 1,000 0,06588155 0,11544866 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,06588155 0,11536464 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,06588155 0,11528074 ! axon guidance GO:0007411 139 73 1,000 0,06748648 0,11800326 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06755419 0,11803586 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06755419 0,11795021 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06755419 0,11786467 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06755419 0,11777926 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06755419 0,11769398 ! mating GO:0007618 17 12 0,000 0,06755419 0,11760882 ! protein complex disassembly GO:0043241 27 12 0,000 0,06755419 0,11752378 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06755419 0,11743886 ! hippocampus development GO:0021766 26 12 0,000 0,06755419 0,11735407 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06755419 0,1172694 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06755419 0,11718485 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,06755419 0,11710042 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06755419 0,11701612 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06755419 0,11693193 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06755419 0,11684787 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06755419 0,11676393 ! drug transport GO:0015893 16 12 0,000 0,06755419 0,1166801 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06755419 0,1165964 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06755419 0,11651282 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06755419 0,11642936 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06755419 0,11634602 ! focal adhesion formation GO:0048041 35 12 0,000 0,06755419 0,11626279 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06755419 0,11617969 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06755419 0,1160967 ! forebrain cell migration GO:0021885 21 12 0,000 0,06755419 0,11601384 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06755419 0,11593109 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06755419 0,11584846 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06755419 0,11576594 ! fear response GO:0042596 26 12 0,000 0,06755419 0,11568355 ! monoamine transport GO:0015844 18 12 0,000 0,06755419 0,11560127 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06755419 0,11551911 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06755419 0,11543706 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06755419 0,11535514 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06755419 0,11527332 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06755419 0,11519163 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06755419 0,11511005 ! protein homotetramerization GO:0051289 21 12 0,000 0,06755419 0,11502858 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06755419 0,11494723 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06755419 0,114866 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06755419 0,11478488 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06755419 0,11470387 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06755419 0,11462298 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06755419 0,1145422 ! cranial nerve development GO:0021545 20 12 0,000 0,06755419 0,11446154 ! fucose catabolic process GO:0019317 22 12 0,000 0,06755419 0,11438099 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06755419 0,11430055 ! histone methylation GO:0016571 26 12 0,000 0,06755419 0,11422023 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06755419 0,11414002 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06755419 0,11405992 ! gland morphogenesis GO:0022612 29 12 0,000 0,06755419 0,11397993 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06755419 0,11390006 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06755419 0,1138203 ! spleen development GO:0048536 22 12 0,000 0,06755419 0,11374065 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,06755419 0,11366111 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06755419 0,11358168 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06755419 0,11350236 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06755419 0,11342316 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06755419 0,11334406 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,06755419 0,11326508 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06755419 0,1131862 ! response to cold GO:0009409 17 12 0,000 0,06755419 0,11310744 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06755419 0,11302878 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06755419 0,11295023 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,06910434 0,11546183 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 121 74 1,000 0,06910434 0,11538171 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,06910434 0,11530169 ! meiotic cell cycle GO:0051321 122 75 1,000 0,07073491 0,11794054 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,072378 0,12059659 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07297449 0,12150631 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07297449 0,12142228 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07297449 0,12133837 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07297449 0,12125457 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,07297449 0,12117089 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07297449 0,12108732 ! lipid localization GO:0010876 28 13 0,000 0,07297449 0,12100387 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,07297449 0,12092054 ! organelle fusion GO:0048284 32 13 0,000 0,07297449 0,12083731 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07297449 0,12075421 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07297449 0,12067122 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07297449 0,12058834 ! endocrine pancreas development GO:0031018 22 13 0,000 0,07297449 0,12050557 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07297449 0,12042292 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07297449 0,12034038 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07297449 0,12025796 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07297449 0,12017565 ! methionine metabolic process GO:0006555 27 13 0,000 0,07297449 0,12009345 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07297449 0,12001136 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,07297449 0,11992938 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,07297449 0,11984752 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,07297449 0,11976577 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,07297449 0,11968413 ! response to X-ray GO:0010165 25 13 0,000 0,07297449 0,1196026 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07297449 0,11952118 ! exocrine system development GO:0035272 32 13 0,000 0,07297449 0,11943988 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,07297449 0,11935868 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07297449 0,11927759 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07297449 0,11919662 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07297449 0,11911575 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07297449 0,119035 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07297449 0,11895435 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07297449 0,11887381 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,07297449 0,11879338 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07297449 0,11871306 ! regulation of cellular pH GO:0030641 22 13 0,000 0,07297449 0,11863285 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07297449 0,11855275 ! ribosome assembly GO:0042255 17 13 0,000 0,07297449 0,11847275 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07297449 0,11839286 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07297449 0,11831308 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07297449 0,11823341 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07297449 0,11815385 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07297449 0,11807439 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07297449 0,11799504 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07297449 0,11791579 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,07297449 0,11783666 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07297449 0,11775762 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07297449 0,1176787 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07297449 0,11759988 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07297449 0,11752116 ! embryonic placenta development GO:0001892 23 13 0,000 0,07297449 0,11744255 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,07297449 0,11736405 ! insulin secretion GO:0030073 23 13 0,000 0,07297449 0,11728565 ! actin filament polymerization GO:0030041 24 13 0,000 0,07297449 0,11720736 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,07297449 0,11712916 ! acrosome reaction GO:0007340 18 13 0,000 0,07297449 0,11705108 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,07403341 0,11867048 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,07403341 0,11859147 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,07738041 0,12387043 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,07738041 0,12378807 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,07738041 0,12370582 ! rRNA transcription GO:0009303 25 14 0,000 0,07836346 0,12519421 ! lactation GO:0007595 26 14 0,000 0,07836346 0,12511113 ! reproductive cellular process GO:0048610 20 14 0,000 0,07836346 0,12502817 ! tRNA modification GO:0006400 20 14 0,000 0,07836346 0,12494531 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,07836346 0,12486256 ! regulation of S phase GO:0033261 23 14 0,000 0,07836346 0,12477993 ! water transport GO:0006833 21 14 0,000 0,07836346 0,1246974 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07836346 0,12461499 ! non-recombinational repair GO:0000726 25 14 0,000 0,07836346 0,12453268 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,07836346 0,12445048 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07836346 0,12436839 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,07836346 0,1242864 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,07836346 0,12420453 ! RNA polyadenylation GO:0043631 30 14 0,000 0,07836346 0,12412276 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07836346 0,1240411 ! palate development GO:0060021 31 14 0,000 0,07836346 0,12395955 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,07836346 0,1238781 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07836346 0,12379676 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,07836346 0,12371553 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,07836346 0,12363441 ! arginine metabolic process GO:0006525 17 14 0,000 0,07836346 0,12355339 ! regulation of heart rate GO:0002027 24 14 0,000 0,07836346 0,12347248 ! organic alcohol transport GO:0015850 29 14 0,000 0,07836346 0,12339167 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,07836346 0,12331097 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,07836346 0,12323037 ! embryo implantation GO:0007566 30 14 0,000 0,07836346 0,12314988 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07836346 0,1230695 ! L-amino acid transport GO:0015807 30 14 0,000 0,07836346 0,12298922 ! bone mineralization GO:0030282 17 14 0,000 0,07836346 0,12290904 ! stem cell development GO:0048864 43 14 0,000 0,07836346 0,12282897 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,07836346 0,12274901 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,07836346 0,12266914 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07836346 0,12258938 ! cerebellum development GO:0021549 21 14 0,000 0,07836346 0,12250973 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,07836346 0,12243018 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07836346 0,12235073 ! response to gamma radiation GO:0010332 28 14 0,000 0,07836346 0,12227138 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,07836346 0,12219214 ! cofactor transport GO:0051181 26 14 0,000 0,07836346 0,122113 ! NADP metabolic process GO:0006739 24 14 0,000 0,07836346 0,12203396 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,07836346 0,12195503 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07836346 0,12187619 ! intestinal absorption GO:0050892 25 14 0,000 0,07836346 0,12179746 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,07836346 0,12171883 ! oxygen transport GO:0015671 21 14 0,000 0,07836346 0,12164031 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07836346 0,12156188 ! male genitalia development GO:0030539 24 14 0,000 0,07836346 0,12148355 ! regulation of axon extension GO:0030516 37 14 0,000 0,07836346 0,12140533 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,07836346 0,1213272 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,07836346 0,12124918 ! protein import into nucleus GO:0006606 158 80 1,000 0,0790716 0,12226625 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,08077434 0,12481893 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 161 81 1,000 0,08077434 0,12473881 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,08077434 0,1246588 ! response to drug GO:0042493 143 82 1,000 0,08248844 0,12722255 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,08372127 0,12904124 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08372127 0,12895863 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,08372127 0,12887612 ! superoxide anion generation GO:0042554 20 15 0,000 0,08372127 0,12879372 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,08372127 0,12871143 ! copper ion transport GO:0006825 20 15 0,000 0,08372127 0,12862924 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,08372127 0,12854715 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,08372127 0,12846517 ! sulfate transport GO:0008272 23 15 0,000 0,08372127 0,12838329 ! response to cAMP GO:0051591 22 15 0,000 0,08372127 0,12830152 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,08372127 0,12821985 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,08372127 0,12813828 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,08372127 0,12805682 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,08372127 0,12797547 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,08372127 0,12789421 ! response to hexose stimulus GO:0009746 22 15 0,000 0,08372127 0,12781306 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,08372127 0,12773201 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,08372127 0,12765107 ! pituitary gland development GO:0021983 29 15 0,000 0,08372127 0,12757022 ! vesicle coating GO:0006901 33 15 0,000 0,08372127 0,12748948 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,08372127 0,12740884 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,08372127 0,12732831 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,08372127 0,12724787 ! regulation of exocytosis GO:0017157 22 15 0,000 0,08372127 0,12716754 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,08372127 0,12708731 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,08372127 0,12700718 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,08372127 0,12692715 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,08372127 0,12684722 ! regulation of vasodilation GO:0042312 26 15 0,000 0,08372127 0,12676739 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,08372127 0,12668766 ! mRNA splice site selection GO:0006376 38 15 0,000 0,08372127 0,12660803 ! tissue regeneration GO:0042246 26 15 0,000 0,08372127 0,12652851 ! water homeostasis GO:0030104 27 15 0,000 0,08372127 0,12644908 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08372127 0,12636975 ! muscle maintenance GO:0046716 26 15 0,000 0,08372127 0,12629052 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,08372127 0,12621139 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,08372127 0,12613236 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,08372127 0,12605343 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08372127 0,1259746 ! heme biosynthetic process GO:0006783 29 15 0,000 0,08372127 0,12589586 ! cell killing GO:0001906 29 15 0,000 0,08372127 0,12581723 ! detection of bacterium GO:0016045 18 15 0,000 0,08372127 0,12573869 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,08372127 0,12566025 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,08372127 0,12558191 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,08372127 0,12550367 ! peptide hormone processing GO:0016486 23 15 0,000 0,08372127 0,12542552 ! negative regulation of growth GO:0045926 155 84 1,000 0,08594994 0,12868423 ! regulation of ligase activity GO:0051340 142 84 1,000 0,08594994 0,1286042 ! nucleosome assembly GO:0006334 122 85 1,000 0,08769698 0,13113669 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,08769698 0,13105524 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,08769698 0,13097388 GO:0002696|positive regulation of leukocyte activation, ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,08904812 0,13290929 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,08904812 0,13282689 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,08904812 0,1327446 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,08904812 0,1326624 ! bone remodeling GO:0046849 27 16 0,000 0,08904812 0,13258031 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,08904812 0,13249832 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,08904812 0,13241643 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,08904812 0,13233464 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,08904812 0,13225295 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,08904812 0,13217136 ! startle response GO:0001964 28 16 0,000 0,08904812 0,13208988 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,08904812 0,13200849 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,08904812 0,1319272 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,08904812 0,13184602 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,08904812 0,13176493 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,08904812 0,13168395 ! protein polyubiquitination GO:0000209 34 16 0,000 0,08904812 0,13160306 ! glutamate metabolic process GO:0006536 22 16 0,000 0,08904812 0,13152227 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,08904812 0,13144158 ! response to osmotic stress GO:0006970 25 16 0,000 0,08904812 0,13136099 ! lysosomal transport GO:0007041 26 16 0,000 0,08904812 0,1312805 ! fructose metabolic process GO:0006000 25 16 0,000 0,08904812 0,13120011 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08904812 0,13111982 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08904812 0,13103962 ! intermediate filament-based process GO:0045103 32 16 0,000 0,08904812 0,13095952 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,08904812 0,13087952 ! negative regulation of immune response GO:0050777 35 16 0,000 0,08904812 0,13079962 ! axon cargo transport GO:0008088 43 16 0,000 0,08904812 0,13071982 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,08904812 0,13064011 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,08904812 0,1305605 ! neuron recognition GO:0008038 35 16 0,000 0,08904812 0,13048099 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,08904812 0,13040157 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,08904812 0,13032225 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,08904812 0,13024303 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,08904812 0,1301639 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,08904812 0,13008487 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,08904812 0,13000593 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08904812 0,12992709 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,08904812 0,12984835 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,08904812 0,1297697 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,08904812 0,12969115 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,08904812 0,12961269 ! defense response to virus GO:0051607 37 16 0,000 0,08904812 0,12953433 ! chromatin assembly GO:0031497 124 86 1,000 0,08945463 0,13004703 ! mitochondrion organization GO:0007005 148 86 1,000 0,08945463 0,1299685 ! protein localization in nucleus GO:0034504 176 87 1,000 0,09122272 0,13245737 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,09434418 0,13690717 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,09434418 0,13682465 ! metencephalon development GO:0022037 30 17 0,000 0,09434418 0,13674222 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,09434418 0,1366599 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,09434418 0,13657767 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,09434418 0,13649554 ! signal complex assembly GO:0007172 41 17 0,000 0,09434418 0,13641352 ! gene silencing by RNA GO:0031047 36 17 0,000 0,09434418 0,13633159 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,09434418 0,13624975 ! glial cell development GO:0021782 27 17 0,000 0,09434418 0,13616802 ! limbic system development GO:0021761 36 17 0,000 0,09434418 0,13608638 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,09434418 0,13600485 ! adult walking behavior GO:0007628 33 17 0,000 0,09434418 0,13592341 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,09434418 0,13584206 ! heart looping GO:0001947 30 17 0,000 0,09434418 0,13576082 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,09434418 0,13567967 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,09434418 0,13559862 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,09434418 0,13551767 ! glycine metabolic process GO:0006544 28 17 0,000 0,09434418 0,13543681 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,09434418 0,13535605 ! NAD metabolic process GO:0019674 29 17 0,000 0,09434418 0,13527538 ! membrane budding GO:0006900 37 17 0,000 0,09434418 0,13519481 ! DNA integration GO:0015074 29 17 0,000 0,09434418 0,13511434 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,09434418 0,13503396 ! regulation of protein binding GO:0043393 33 17 0,000 0,09434418 0,13495368 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,09434418 0,13487349 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,09434418 0,1347934 ! genitalia development GO:0048806 30 17 0,000 0,09434418 0,13471341 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,09434418 0,13463351 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,09434418 0,1345537 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,09434418 0,13447399 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,09434418 0,13439437 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,09434418 0,13431485 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,09434418 0,13423542 ! steroid catabolic process GO:0006706 31 17 0,000 0,09434418 0,13415608 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,09434418 0,13407684 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,09434418 0,13399769 ! gas transport GO:0015669 25 17 0,000 0,09434418 0,13391864 ! organic cation transport GO:0015695 31 17 0,000 0,09434418 0,13383968 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,09434418 0,13376081 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,09434418 0,13368203 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,09434418 0,13360335 ! sex differentiation GO:0007548 145 90 1,000 0,0965878 0,13670014 ! protein-DNA complex assembly GO:0065004 130 90 1,000 0,0965878 0,13661978 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,09960962 0,14081125 ! neuron maturation GO:0042551 42 18 0,000 0,09960962 0,14072856 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,09960962 0,14064597 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,09960962 0,14056348 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,09960962 0,14048109 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,09960962 0,14039879 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,09960962 0,14031659 ! memory GO:0007613 31 18 0,000 0,09960962 0,14023449 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09960962 0,14015248 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,09960962 0,14007057 ! patterning of blood vessels GO:0001569 39 18 0,000 0,09960962 0,13998875 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,09960962 0,13990703 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,09960962 0,1398254 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09960962 0,13974387 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,09960962 0,13966244 ! response to fungus GO:0009620 21 18 0,000 0,09960962 0,1395811 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,09960962 0,13949985 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,09960962 0,1394187 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,09960962 0,13933764 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,09960962 0,13925668 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,09960962 0,13917581 ! vitamin transport GO:0051180 27 18 0,000 0,09960962 0,13909503 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,09960962 0,13901435 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,09960962 0,13893376 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,09960962 0,13885327 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,09960962 0,13877287 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,09960962 0,13869256 ! nerve development GO:0021675 28 18 0,000 0,09960962 0,13861234 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,09960962 0,13853222 ! regulation of defense response GO:0031347 149 92 1,000 0,10021345 0,13929149 ! nucleosome organization GO:0034728 138 92 1,000 0,10021345 0,13921107 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,10204045 0,14166723 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,10204045 0,14158553 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,10204045 0,14150393 ! protein secretion GO:0009306 39 19 0,000 0,10484462 0,14530884 ! positive regulation of translation GO:0045727 30 19 0,000 0,10484462 0,14522519 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,10484462 0,14514163 ! skin development GO:0043588 36 19 0,000 0,10484462 0,14505817 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,10484462 0,1449748 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,10484462 0,14489153 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,10484462 0,14480836 ! bile acid metabolic process GO:0008206 29 19 0,000 0,10484462 0,14472528 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,10484462 0,14464229 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,10484462 0,1445594 ! cerebral cortex development GO:0021987 36 19 0,000 0,10484462 0,14447661 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,10484462 0,14439391 GO:0030968|endoplasmic reticulum unfolded protein response, ! heme metabolic process GO:0042168 36 19 0,000 0,10484462 0,1443113 ! actin filament bundle formation GO:0051017 42 19 0,000 0,10484462 0,14422879 ! neuromuscular junction development GO:0007528 34 19 0,000 0,10484462 0,14414637 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,10484462 0,14406405 ! peptide cross-linking GO:0018149 37 19 0,000 0,10484462 0,14398182 ! protein export from nucleus GO:0006611 36 19 0,000 0,10484462 0,14389969 ! heart process GO:0003015 30 19 0,000 0,10484462 0,14381765 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,10484462 0,1437357 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,10484462 0,14365385 ! visual learning GO:0008542 36 19 0,000 0,10484462 0,14357209 ! cellular pigmentation GO:0033059 36 19 0,000 0,10484462 0,14349042 ! G1 phase GO:0051318 40 19 0,000 0,10484462 0,14340884 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,10484462 0,14332736 ! cell-cell junction organization GO:0045216 35 19 0,000 0,10484462 0,14324597 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,10484462 0,14316467 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,10484462 0,14308347 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,10484462 0,14300236 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,10484462 0,14292133 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,10484462 0,1428404 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,10484462 0,14275957 ! cilium assembly GO:0042384 37 19 0,000 0,10484462 0,14267882 ! peptide hormone secretion GO:0030072 31 19 0,000 0,10484462 0,14259817 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,10943892 0,14876274 ! protein ubiquitination GO:0016567 217 97 1,000 0,10943892 0,14867874 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,11004936 0,14942368 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,11004936 0,1493394 ! positive regulation of ossification GO:0045778 47 20 0,000 0,11004936 0,14925522 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,11004936 0,14917113 ! cAMP metabolic process GO:0046058 36 20 0,000 0,11004936 0,14908714 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,11004936 0,14900324 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,11004936 0,14891943 ! response to alkaloid GO:0043279 38 20 0,000 0,11004936 0,14883572 ! retinoid metabolic process GO:0001523 32 20 0,000 0,11004936 0,14875211 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,11004936 0,14866859 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,11004936 0,14858516 ! cellular response to starvation GO:0009267 33 20 0,000 0,11004936 0,14850182 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,11004936 0,14841858 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,11004936 0,14833544 ! body fluid secretion GO:0007589 31 20 0,000 0,11004936 0,14825238 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,11004936 0,14816942 ! peptide secretion GO:0002790 35 20 0,000 0,11004936 0,14808655 ! stem cell differentiation GO:0048863 53 20 0,000 0,11004936 0,14800377 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,11004936 0,14792109 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,11004936 0,1478385 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,11004936 0,147756 ! sensory perception of pain GO:0019233 30 20 0,000 0,11004936 0,14767359 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,11004936 0,14759128 ! diencephalon development GO:0021536 34 20 0,000 0,11004936 0,14750905 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,11004936 0,14742692 GO:0006626|protein targeting to mitochondrion, ! detection of chemical stimulus GO:0009593 37 20 0,000 0,11004936 0,14734488 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,11004936 0,14726293 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,11004936 0,14718107 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,11004936 0,14709931 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,11004936 0,14701763 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,11004936 0,14693605 ! regulation of glucose import GO:0046324 29 20 0,000 0,11004936 0,14685455 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,11004936 0,14677314 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,11004936 0,14669183 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,11004936 0,14661061 ! negative regulation of translation GO:0017148 29 20 0,000 0,11004936 0,14652947 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,11004936 0,14644843 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,11004936 0,14636747 ! response to virus GO:0009615 160 98 1,000 0,11131034 0,14796281 ! regulation of cell killing GO:0031341 42 21 0,000 0,115224 0,15308059 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,115224 0,15299611 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,115224 0,15291172 ! hormone secretion GO:0046879 38 21 0,000 0,115224 0,15282743 ! glycerol metabolic process GO:0006071 34 21 0,000 0,115224 0,15274323 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,115224 0,15265912 ! axis specification GO:0009798 38 21 0,000 0,115224 0,1525751 ! ovarian follicle development GO:0001541 35 21 0,000 0,115224 0,15249117 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,115224 0,15240734 ! smooth muscle contraction GO:0006939 46 21 0,000 0,115224 0,1523236 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,115224 0,15223995 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,115224 0,1521564 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,115224 0,15207293 ! cell aging GO:0007569 44 21 0,000 0,115224 0,15198956 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,115224 0,15190628 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,115224 0,15182309 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,115224 0,15173999 ! cytolysis GO:0019835 24 21 0,000 0,115224 0,15165698 ! vasodilation GO:0042311 39 21 0,000 0,115224 0,15157406 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,115224 0,15149123 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,115224 0,1514085 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,115224 0,15132585 ! oogenesis GO:0048477 36 21 0,000 0,115224 0,15124329 ! collagen fibril organization GO:0030199 59 21 0,000 0,115224 0,15116083 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,115224 0,15107845 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,115224 0,15099616 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,115224 0,15091397 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,115224 0,15083186 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,115224 0,15074984 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,115224 0,15066791 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,115224 0,15058607 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,115224 0,15050432 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,115224 0,15042266 ! collagen catabolic process GO:0030574 28 21 0,000 0,115224 0,15034108 ! sperm-egg recognition GO:0035036 21 21 0,000 0,115224 0,1502596 ! gut development GO:0048565 39 21 0,000 0,115224 0,1501782 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,12036873 0,15679869 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,12036873 0,15671384 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,12036873 0,15662908 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,12036873 0,15654442 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,12036873 0,15645985 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,12036873 0,15637536 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,12036873 0,15629097 ! regeneration GO:0031099 41 22 0,000 0,12036873 0,15620668 ! keratinization GO:0031424 28 22 0,000 0,12036873 0,15612247 ! sensory perception of taste GO:0050909 28 22 0,000 0,12036873 0,15603835 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,12036873 0,15595432 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,12036873 0,15587039 ! vacuolar transport GO:0007034 36 22 0,000 0,12036873 0,15578654 ! lysosome organization GO:0007040 41 22 0,000 0,12036873 0,15570278 ! central nervous system neuron development GO:0021954 46 22 0,000 0,12036873 0,15561912 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,12036873 0,15553554 ! fucose metabolic process GO:0006004 39 22 0,000 0,12036873 0,15545205 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,12036873 0,15536866 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,12036873 0,15528535 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,12036873 0,15520213 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,12036873 0,155119 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,12036873 0,15503596 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,12036873 0,15495301 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,12036873 0,15487015 ! sarcomere organization GO:0045214 30 22 0,000 0,12036873 0,15478737 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,12036873 0,15470469 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,12036873 0,15462209 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,12036873 0,15453958 ! protein stabilization GO:0050821 39 22 0,000 0,12036873 0,15445716 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,12548372 0,16093488 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,12548372 0,16084914 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,12548372 0,16076349 ! gluconeogenesis GO:0006094 33 23 0,000 0,12548372 0,16067793 ! viral genome replication GO:0019079 41 23 0,000 0,12548372 0,16059246 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,12548372 0,16050709 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,12548372 0,1604218 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,12548372 0,16033661 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,12548372 0,1602515 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,12548372 0,16016649 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,12548372 0,16008156 ! visual behavior GO:0007632 42 23 0,000 0,12548372 0,15999673 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,12548372 0,15991199 ! response to ethanol GO:0045471 46 23 0,000 0,12548372 0,15982733 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,12548372 0,15974277 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,12548372 0,15965829 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,12548372 0,15957391 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,12548372 0,15948961 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,12548372 0,1594054 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,12548372 0,15932128 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,12548372 0,15923725 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,12548372 0,15915331 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,12548372 0,15906946 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,12548372 0,15898569 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,12548372 0,15890202 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,12548372 0,15881843 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,12548372 0,15873493 ! fatty acid transport GO:0015908 44 23 0,000 0,12548372 0,15865151 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,12548372 0,15856819 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,12548372 0,15848495 ! hormone transport GO:0009914 40 23 0,000 0,12548372 0,1584018 ! cell-cell recognition GO:0009988 25 23 0,000 0,12548372 0,15831874 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,12548372 0,15823576 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,12548372 0,15815287 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,12548372 0,15807007 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,12548372 0,15798735 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,12548372 0,15790472 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,13056913 0,16421815 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,13056913 0,16413235 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,13056913 0,16404665 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,13056913 0,16396103 ! vesicle docking GO:0048278 47 24 0,000 0,13056913 0,1638755 ! spinal cord development GO:0021510 47 24 0,000 0,13056913 0,16379006 ! vacuole organization GO:0007033 43 24 0,000 0,13056913 0,1637047 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,13056913 0,16361944 ! digestive system process GO:0022600 39 24 0,000 0,13056913 0,16353427 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,13056913 0,16344918 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,13056913 0,16336418 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,13056913 0,16327928 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,13056913 0,16319446 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,13056913 0,16310972 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,13056913 0,16302508 ! membrane depolarization GO:0051899 39 24 0,000 0,13056913 0,16294052 ! pallium development GO:0021543 49 24 0,000 0,13056913 0,16285605 ! pentose metabolic process GO:0019321 35 24 0,000 0,13056913 0,16277167 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,13056913 0,16268738 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,13056913 0,16260317 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,13056913 0,16251905 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,13056913 0,16243502 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,13056913 0,16235107 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,13056913 0,16226721 ! regulation of amine transport GO:0051952 40 24 0,000 0,13056913 0,16218344 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,13562514 0,16837672 ! myelination GO:0042552 45 25 0,000 0,13562514 0,16828988 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,13562514 0,16820313 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,13562514 0,16811648 ! phototransduction GO:0007602 33 25 0,000 0,13562514 0,16802991 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,13562514 0,16794343 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,13562514 0,16785704 ! sperm motility GO:0030317 31 25 0,000 0,13562514 0,16777073 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,13562514 0,16768452 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,13562514 0,1675984 ! receptor metabolic process GO:0043112 46 25 0,000 0,13562514 0,16751236 ! chromosome condensation GO:0030261 45 25 0,000 0,13562514 0,16742641 ! response to starvation GO:0042594 42 25 0,000 0,13562514 0,16734055 ! osteoblast differentiation GO:0001649 60 25 0,000 0,13562514 0,16725478 ! neural crest cell development GO:0014032 54 25 0,000 0,13562514 0,1671691 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,13562514 0,1670835 ! negative regulation of cell development GO:0010721 73 25 0,000 0,13562514 0,16699799 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,13562514 0,16691257 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,13562514 0,16682724 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,13562514 0,16674199 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,13562514 0,16665683 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,13562514 0,16657176 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,13562514 0,16648677 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,13562514 0,16640188 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,13562514 0,16631706 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,13562514 0,16623234 ! telomere organization GO:0032200 43 25 0,000 0,13562514 0,1661477 GO:0000723|telomere maintenance, ! liver development GO:0001889 53 25 0,000 0,13562514 0,16606314 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,14065191 0,17213046 ! embryonic pattern specification GO:0009880 44 26 0,000 0,14065191 0,17204295 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,14065191 0,17195553 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,14065191 0,1718682 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,14065191 0,17178096 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,14065191 0,17169381 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,14065191 0,17160674 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,14065191 0,17151976 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,14065191 0,17143287 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,14065191 0,17134607 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,14065191 0,17125936 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,14065191 0,17117273 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,14065191 0,17108619 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,14065191 0,17099974 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,14065191 0,17091338 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,14065191 0,1708271 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,14065191 0,17074091 ! leukocyte proliferation GO:0070661 52 26 0,000 0,14065191 0,17065481 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,14065191 0,1705688 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,14065191 0,17048287 ! neuron fate commitment GO:0048663 48 27 0,000 0,14564961 0,17645164 ! iron ion transport GO:0006826 59 27 0,000 0,14564961 0,17636284 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,14564961 0,17627413 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,14564961 0,1761855 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,14564961 0,17609697 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,14564961 0,17600852 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,14564961 0,17592016 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,14564961 0,1758319 ! autophagy GO:0006914 41 27 0,000 0,14564961 0,17574371 ! response to toxin GO:0009636 47 27 0,000 0,14564961 0,17565562 ! base-excision repair GO:0006284 41 27 0,000 0,14564961 0,17556762 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,14564961 0,1754797 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,14564961 0,17539188 ! glutathione metabolic process GO:0006749 39 27 0,000 0,14564961 0,17530414 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,14564961 0,17521648 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,14564961 0,17512892 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,14564961 0,17504144 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,15061842 0,18092257 ! circadian rhythm GO:0007623 50 28 0,000 0,15061842 0,18083229 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,15061842 0,1807421 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,15061842 0,180652 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,15061842 0,18056199 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,15061842 0,18047207 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,15061842 0,18038223 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,15061842 0,18029249 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,15061842 0,18020284 ! synaptogenesis GO:0007416 42 28 0,000 0,15061842 0,18011328 ! lipid oxidation GO:0034440 43 28 0,000 0,15061842 0,1800238 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,15061842 0,17993441 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,15061842 0,17984512 ! translational initiation GO:0006413 65 29 0,000 0,15555849 0,18565165 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,15555849 0,1855596 ! regulation of pH GO:0006885 43 29 0,000 0,15555849 0,18546765 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,15555849 0,18537579 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,15555849 0,18528402 ! catechol metabolic process GO:0009712 54 29 0,000 0,15555849 0,18519234 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,15555849 0,18510075 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,15555849 0,18500925 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,15555849 0,18491785 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,15555849 0,18482653 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,15555849 0,1847353 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,15555849 0,18464416 ! detection of light stimulus GO:0009583 38 29 0,000 0,15555849 0,18455312 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,15555849 0,18446216 ! tissue homeostasis GO:0001894 48 29 0,000 0,15555849 0,18437129 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,15555849 0,18428051 ! phenol metabolic process GO:0018958 55 30 0,000 0,16046999 0,19000531 ! zinc ion transport GO:0006829 45 30 0,000 0,16046999 0,18991185 ! membrane docking GO:0022406 61 30 0,000 0,16046999 0,18981848 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,16046999 0,18972521 ! cell junction assembly GO:0034329 78 30 0,000 0,16046999 0,18963202 ! regulation of innate immune response GO:0045088 51 30 0,000 0,16046999 0,18953893 ! myofibril assembly GO:0030239 47 30 0,000 0,16046999 0,18944592 GO:0055002|striated muscle cell development, ! determination of left/right symmetry GO:0007368 47 30 0,000 0,16046999 0,18935301 ! phospholipid transport GO:0015914 51 30 0,000 0,16046999 0,18926019 ! ensheathment of neurons GO:0007272 57 30 0,000 0,16046999 0,18916746 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,16046999 0,18907482 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,16046999 0,18898228 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,16046999 0,18888982 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,16046999 0,18879745 ! eye morphogenesis GO:0048592 60 30 0,000 0,16046999 0,18870518 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,16535309 0,19435248 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,16535309 0,19425758 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,16535309 0,19416277 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,16535309 0,19406806 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,16535309 0,19397344 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,16535309 0,19387891 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,16535309 0,19378447 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,16535309 0,19369013 ! ovulation cycle process GO:0022602 49 31 0,000 0,16535309 0,19359588 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,16535309 0,19350171 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,16535309 0,19340764 ! peptide transport GO:0015833 55 31 0,000 0,16535309 0,19331367 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,16535309 0,19321978 ! iron ion homeostasis GO:0055072 54 31 0,000 0,16535309 0,19312598 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,16535309 0,19303228 ! mesoderm formation GO:0001707 69 31 0,000 0,16535309 0,19293866 ! natural killer cell activation GO:0030101 45 31 0,000 0,16535309 0,19284514 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,16535309 0,19275171 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,16535309 0,19265837 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,16535309 0,19256511 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,16535309 0,19247195 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,16535309 0,19237888 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,17020794 0,19793152 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,17020794 0,1978359 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,17020794 0,19774037 ! cholesterol transport GO:0030301 56 32 0,000 0,17020794 0,19764494 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,17020794 0,19754959 ! spliceosome assembly GO:0000245 67 32 0,000 0,17020794 0,19745434 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,17020794 0,19735919 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,17020794 0,19726412 ! response to ionizing radiation GO:0010212 65 32 0,000 0,17020794 0,19716914 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,17020794 0,19707426 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,17020794 0,19697947 ! muscle cell development GO:0055001 49 32 0,000 0,17020794 0,19688476 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,17020794 0,19679015 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,17020794 0,19669563 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,17020794 0,1966012 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,17020794 0,19650687 ! ovulation cycle GO:0042698 51 32 0,000 0,17020794 0,19641262 ! peripheral nervous system development GO:0007422 64 32 0,000 0,17020794 0,19631846 ! BMP signaling pathway GO:0030509 64 32 0,000 0,17020794 0,19622439 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,17020794 0,19613042 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,17020794 0,19603653 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,17503472 0,2014993 ! post-embryonic development GO:0009791 69 33 0,000 0,17503472 0,20140293 ! protein targeting to membrane GO:0006612 68 33 0,000 0,17503472 0,20130666 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,17503472 0,20121048 ! ceramide metabolic process GO:0006672 64 33 0,000 0,17503472 0,20111439 ! formation of primary germ layer GO:0001704 72 33 0,000 0,17503472 0,20101839 ! cell fate specification GO:0001708 52 33 0,000 0,17503472 0,20092249 ! sterol transport GO:0015918 57 33 0,000 0,17503472 0,20082667 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,17503472 0,20073095 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,17503472 0,20063532 ! adult locomotory behavior GO:0008344 59 33 0,000 0,17503472 0,20053978 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,17503472 0,20044433 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,17503472 0,20034897 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,17983358 0,20574398 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,17983358 0,2056462 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,17983358 0,2055485 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,17983358 0,2054509 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,17983358 0,20535339 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,17983358 0,20525597 ! mismatch repair GO:0006298 46 34 0,000 0,17983358 0,20515865 ! spermatid development GO:0007286 63 34 0,000 0,17983358 0,20506142 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,17983358 0,20496428 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,17983358 0,20486723 ! negative regulation of secretion GO:0051048 63 35 0,000 0,18460468 0,21020297 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,18460468 0,21010353 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,18460468 0,21000419 ! odontogenesis GO:0042476 66 35 0,000 0,18460468 0,20990495 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,18460468 0,2098058 ! female gonad development GO:0008585 58 35 0,000 0,18460468 0,20970674 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,18460468 0,20960777 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,18460468 0,2095089 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,18460468 0,20941012 ! cytokine production GO:0001816 59 35 0,000 0,18460468 0,20931144 ! vesicle localization GO:0051648 64 35 0,000 0,18460468 0,20921285 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,18934819 0,21448764 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,18934819 0,21438671 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,18934819 0,21428587 ! cell junction organization GO:0034330 86 36 0,000 0,18934819 0,21418512 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,18934819 0,21408447 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,18934819 0,21398391 ! positive regulation of cell development GO:0010720 80 36 0,000 0,18934819 0,21388345 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,18934819 0,21378308 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,18934819 0,21368281 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,18934819 0,21358263 ! aerobic respiration GO:0009060 55 36 0,000 0,18934819 0,21348254 ! embryonic organ development GO:0048568 57 36 0,000 0,18934819 0,21338255 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,18934819 0,21328265 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,18934819 0,21318285 ! RNA export from nucleus GO:0006405 56 37 0,000 0,19406426 0,21839037 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,19406426 0,21828827 ! actomyosin structure organization GO:0031032 62 37 0,000 0,19406426 0,21818627 ! organic anion transport GO:0015711 68 37 0,000 0,19406426 0,21808436 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,19406426 0,21798254 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,19406426 0,21788083 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,19406426 0,2177792 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,19406426 0,21767767 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,19406426 0,21757624 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,19406426 0,2174749 ! spermatid differentiation GO:0048515 66 37 0,000 0,19406426 0,21737366 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,19875305 0,22252203 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,19875305 0,22241853 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,19875305 0,22231513 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,19875305 0,22221182 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,19875305 0,22210861 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,19875305 0,22200549 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,19875305 0,22190248 ! lipid homeostasis GO:0055088 67 38 0,000 0,19875305 0,22179955 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,19875305 0,22169673 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,19875305 0,22159399 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,19875305 0,22149136 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,19875305 0,22138881 ! mRNA catabolic process GO:0006402 71 39 0,000 0,20341471 0,22647654 ! mammary gland development GO:0030879 86 39 0,000 0,20341471 0,22637179 ! learning GO:0007612 77 39 0,000 0,20341471 0,22626713 ! ear morphogenesis GO:0042471 60 39 0,000 0,20341471 0,22616257 ! organic ether metabolic process GO:0018904 55 39 0,000 0,20341471 0,22605811 ! ion transmembrane transport GO:0034220 66 39 0,000 0,20341471 0,22595374 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,20341471 0,22584947 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,20341471 0,2257453 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,20341471 0,22564122 ! RNA modification GO:0009451 57 39 0,000 0,20341471 0,22553724 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,20341471 0,22543335 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,20804941 0,23046357 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,20804941 0,23035752 ! feeding behavior GO:0007631 59 40 0,000 0,20804941 0,23025156 ! negative regulation of binding GO:0051100 72 40 0,000 0,20804941 0,23014569 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,20804941 0,23003993 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,20804941 0,22993426 ! maintenance of protein location GO:0045185 91 40 0,000 0,20804941 0,22982869 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,2126573 0,23481113 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,2126573 0,23470342 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,2126573 0,23459581 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,2126573 0,23448829 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,2126573 0,23438088 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,2126573 0,23427356 ! T cell differentiation GO:0030217 81 41 0,000 0,2126573 0,23416634 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,2126573 0,23405922 ! female gamete generation GO:0007292 61 41 0,000 0,2126573 0,2339522 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,2126573 0,23384527 ! regulation of tube size GO:0035150 71 42 0,000 0,21723852 0,23877382 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,21723852 0,23866479 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,21723852 0,23855586 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,21723852 0,23844703 ! regulation of protein secretion GO:0050708 71 42 0,000 0,21723852 0,2383383 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,21723852 0,23822967 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,22179324 0,24311369 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,22179324 0,24300298 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,22179324 0,24289237 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,22179324 0,24278187 ! striated muscle contraction GO:0006941 77 43 0,000 0,22179324 0,24267146 ! phagocytosis GO:0006909 90 43 0,000 0,22179324 0,24256116 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,22179324 0,24245095 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,22632161 0,24728874 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,22632161 0,24717649 ! double-strand break repair GO:0006302 81 44 0,000 0,22632161 0,24706434 ! B cell differentiation GO:0030183 107 44 0,000 0,22632161 0,24695229 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,22632161 0,24684035 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,22632161 0,2467285 ! maintenance of location in cell GO:0051651 97 44 0,000 0,22632161 0,24661676 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,23082378 0,25140879 ! glycolysis GO:0006096 65 45 0,000 0,23082378 0,25129503 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,23082378 0,25118138 ! leukocyte migration GO:0050900 68 45 0,000 0,23082378 0,25106782 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,23082378 0,25095437 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,23082378 0,25084102 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,23082378 0,25072777 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,23082378 0,25061463 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,23082378 0,25050159 ! cell growth GO:0016049 84 45 0,000 0,23082378 0,25038865 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,2352999 0,25512914 ! positive regulation of defense response GO:0031349 76 47 0,000 0,23975012 0,25983729 ! response to calcium ion GO:0051592 81 47 0,000 0,23975012 0,2597203 ! endosome transport GO:0016197 108 47 0,000 0,23975012 0,25960341 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,23975012 0,25948663 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,23975012 0,25936996 ! JNK cascade GO:0007254 91 47 0,000 0,23975012 0,25925339 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,23975012 0,25913692 ! mitochondrial transport GO:0006839 82 48 0,000 0,24417459 0,26380065 ! cellular component disassembly GO:0022411 86 48 0,000 0,24417459 0,26368225 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,24417459 0,26356396 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,24417459 0,26344576 ! activation of caspase activity GO:0006919 84 48 0,000 0,24417459 0,26332768 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,24417459 0,2632097 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,24417459 0,26309183 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,24857345 0,2677116 ! regulation of action potential GO:0001508 95 49 0,000 0,24857345 0,26759182 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,24857345 0,26747215 ! regulation of ion transport GO:0043269 77 49 0,000 0,24857345 0,26735258 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,24857345 0,26723312 ! peptide metabolic process GO:0006518 76 49 0,000 0,24857345 0,26711377 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,24857345 0,26699452 ! endocrine system development GO:0035270 104 49 0,000 0,24857345 0,26687538 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,24857345 0,26675634 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,24857345 0,26663742 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,24857345 0,26651859 ! neuromuscular process GO:0050905 99 50 0,000 0,25294686 0,27108692 ! regulation of ossification GO:0030278 117 50 0,000 0,25294686 0,27096623 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,25294686 0,27084564 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,25294686 0,27072515 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,25729496 0,27525641 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,25729496 0,27513408 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,25729496 0,27501185 ! excretion GO:0007588 83 51 0,000 0,25729496 0,27488973 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,25729496 0,27476772 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,25729496 0,27464582 ! vesicle organization GO:0016050 107 51 0,000 0,25729496 0,27452402 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,26161789 0,2790127 ! synapse organization GO:0050808 85 52 0,000 0,26161789 0,27888908 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,26591581 0,28334519 ! RNA catabolic process GO:0006401 93 53 0,000 0,26591581 0,28321976 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,26591581 0,28309444 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,26591581 0,28296924 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,26591581 0,28284414 ! cell maturation GO:0048469 100 53 0,000 0,26591581 0,28271915 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,26591581 0,28259428 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,26591581 0,28246951 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,27018885 0,2868819 ! cell recognition GO:0008037 85 54 0,000 0,27018885 0,28675535 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,27018885 0,28662892 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,27018885 0,28650259 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,27018885 0,28637638 ! chloride transport GO:0006821 90 55 0,000 0,27443716 0,29075113 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,27443716 0,29062316 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,27443716 0,2904953 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,27443716 0,29036755 ! aging GO:0007568 103 55 0,000 0,27443716 0,29023992 ! gastrulation GO:0007369 112 55 0,000 0,27443716 0,2901124 ! nuclear export GO:0051168 97 55 0,000 0,27443716 0,28998499 ! regulation of actin filament length GO:0030832 105 56 0,000 0,27866088 0,29431874 ! sensory perception of smell GO:0007608 80 56 0,000 0,27866088 0,2941896 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,27866088 0,29406056 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,27866088 0,29393165 ! proton transport GO:0015992 94 56 0,000 0,27866088 0,29380284 ! maintenance of location GO:0051235 118 57 0,000 0,28286016 0,29809967 ! hydrogen transport GO:0006818 97 58 0,000 0,28703512 0,30236712 ! regulation of endocytosis GO:0030100 91 58 0,000 0,28703512 0,30223479 ! adult behavior GO:0030534 99 58 0,000 0,28703512 0,30210258 ! regulation of cellular component size GO:0032535 109 59 0,000 0,29118592 0,30633727 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,29118592 0,30620338 GO:0032313|regulation of Rab GTPase activity, ! DNA catabolic process GO:0006308 86 59 0,000 0,29118592 0,30606961 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,29531269 0,31027176 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,29531269 0,31013633 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,29531269 0,31000102 ! regulation of heart contraction GO:0008016 110 60 0,000 0,29531269 0,30986582 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,29941557 0,31403394 ! tRNA processing GO:0008033 89 61 0,000 0,29941557 0,31389711 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,29941557 0,3137604 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,3034947 0,3178965 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,30755021 0,32200427 ! detection of external stimulus GO:0009581 91 63 0,000 0,30755021 0,32186421 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,30755021 0,32172427 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,31158225 0,32580047 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,31158225 0,32565894 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,31158225 0,32551754 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,31158225 0,32537625 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,31559093 0,32941943 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,31559093 0,32927658 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,31957641 0,33329035 ! actin filament organization GO:0007015 148 66 0,000 0,31957641 0,33314595 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,31957641 0,33300167 ! extracellular matrix organization GO:0030198 133 66 0,000 0,31957641 0,33285751 ! secondary metabolic process GO:0019748 116 66 0,000 0,31957641 0,33271348 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,32353881 0,33669307 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,32353881 0,33654751 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,32353881 0,33640207 ! hexose catabolic process GO:0019320 104 67 0,000 0,32353881 0,33625675 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,32353881 0,33611157 ! activation of immune response GO:0002253 105 67 0,000 0,32353881 0,3359665 ! amino acid transport GO:0006865 125 68 0,000 0,32747827 0,33991058 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,32747827 0,339764 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,32747827 0,33961755 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,32747827 0,33947123 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,33139492 0,34338336 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,33139492 0,34323555 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,33139492 0,34308785 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,33139492 0,34294029 ! antigen processing and presentation GO:0019882 104 69 0,000 0,33139492 0,34279285 ! amine catabolic process GO:0009310 117 71 0,000 0,3391603 0,35067455 ! humoral immune response GO:0006959 109 71 0,000 0,3391603 0,35052392 ! B cell activation GO:0042113 160 71 0,000 0,3391603 0,35037341 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,3391603 0,35022304 ! regulation of immune effector process GO:0002697 137 71 0,000 0,3391603 0,35007279 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,3430093 0,35389381 ! learning or memory GO:0007611 147 73 0,000 0,346836 0,35768856 ! regulation of blood pressure GO:0008217 125 73 0,000 0,346836 0,35753531 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,346836 0,35738219 ! fertilization GO:0009566 90 73 0,000 0,346836 0,3572292 ! transition metal ion transport GO:0000041 126 74 0,000 0,35064055 0,36099322 ! neurotransmitter transport GO:0006836 123 74 0,000 0,35064055 0,36083882 ! exocytosis GO:0006887 133 74 0,000 0,35064055 0,36068455 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,35064055 0,36053041 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,35064055 0,3603764 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,35442305 0,3641084 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,35442305 0,363953 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,35442305 0,36379773 ! rhythmic process GO:0048511 128 75 0,000 0,35442305 0,36364259 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,35442305 0,36348758 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,35818365 0,36718785 ! defense response to bacterium GO:0042742 89 76 0,000 0,35818365 0,36703146 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,35818365 0,36687521 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,35818365 0,36671909 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,36192247 0,3703894 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,36192247 0,37023192 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,36563964 0,37387546 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,36933527 0,37749391 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,36933527 0,37733361 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,36933527 0,37717345 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,36933527 0,37701343 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,37300949 0,38060256 ! response to metal ion GO:0010038 140 80 0,000 0,37300949 0,38044122 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,37300949 0,38028001 ! inorganic anion transport GO:0015698 138 80 0,000 0,37300949 0,38011895 ! T cell activation GO:0042110 168 81 0,000 0,37666243 0,383679 ! digestion GO:0007586 112 81 0,000 0,37666243 0,38351663 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,37666243 0,3833544 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,38029421 0,38688705 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,38029421 0,38672353 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,38029421 0,38656015 ! regulation of lyase activity GO:0051339 160 83 0,000 0,38390495 0,39006558 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,38749477 0,39354682 ! negative regulation of transport GO:0051051 153 84 0,000 0,38749477 0,39338076 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,38749477 0,39321485 ! response to unfolded protein GO:0006986 131 85 0,000 0,39106379 0,39666925 ! amine biosynthetic process GO:0009309 138 86 0,000 0,39461213 0,40009978 ! response to inorganic substance GO:0010035 153 86 0,000 0,39461213 0,39993125 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,39461213 0,39976286 ! alcohol catabolic process GO:0046164 130 86 0,000 0,39461213 0,39959461 ! amine transport GO:0015837 155 86 0,000 0,39461213 0,3994265 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,39813991 0,40282785 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,39813991 0,40265853 ! cellular respiration GO:0045333 135 88 0,000 0,40164726 0,406035 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,40164726 0,40586447 ! gland development GO:0048732 206 88 0,000 0,40164726 0,40569408 ! regulation of neurological system process GO:0031644 148 88 0,000 0,40164726 0,40552384 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,40164726 0,40535373 ! cellular defense response GO:0006968 114 89 0,000 0,40513428 0,4087015 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,40860109 0,41202608 ! sterol metabolic process GO:0016125 152 91 0,000 0,41204782 0,41532763 ! response to protein stimulus GO:0051789 149 91 0,000 0,41204782 0,4151537 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,41204782 0,41497993 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,41547457 0,41825599 ! vitamin metabolic process GO:0006766 139 92 0,000 0,41547457 0,41808106 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,41888146 0,42133311 ! regulation of membrane potential GO:0042391 164 93 0,000 0,41888146 0,42115704 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,42226861 0,42438524 ! female pregnancy GO:0007565 164 94 0,000 0,42226861 0,42420805 ! regulation of T cell activation GO:0050863 158 94 0,000 0,42226861 0,424031 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,42563613 0,42723426 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,42898413 0,43041527 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,42898413 0,43023585 ! positive regulation of immune response GO:0050778 156 96 0,000 0,42898413 0,43005659 ! detection of stimulus GO:0051606 151 96 0,000 0,42898413 0,42987747 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,43231272 0,43303264 ! hormone metabolic process GO:0042445 157 97 0,000 0,43231272 0,43285244 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,43562203 0,43598444 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,43562203 0,43580316 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,43891215 0,43891215