pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6483-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 5,000 9,738E-12 2,379E-08 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 8,000 2,124E-11 2,594E-08 ! phospholipid dephosphorylation GO:0046839 12 5 3,000 3,939E-09 3,208E-06 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 3,000 1,177E-08 7,187E-06 ! auditory receptor cell differentiation GO:0042491 36 17 4,000 2,432E-08 1,188E-05 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 4,000 2,432E-08 9,901E-06 ! negative regulation of focal adhesion formation GO:0051895 21 7 3,000 2,734E-08 9,542E-06 ! regulation of focal adhesion formation GO:0051893 23 8 3,000 5,445E-08 1,663E-05 ! lung development GO:0030324 165 69 6,000 9,103E-08 2,471E-05 ! macrophage differentiation GO:0030225 15 9 3,000 9,761E-08 2,385E-05 ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 4,000 1,013E-07 2,249E-05 ! inner ear receptor cell differentiation GO:0060113 42 22 4,000 1,013E-07 2,062E-05 ! respiratory tube development GO:0030323 171 72 6,000 1,226E-07 2,304E-05 ! respiratory system development GO:0060541 175 74 6,000 1,485E-07 2,59E-05 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 3,000 1,62E-07 2,638E-05 ! mechanoreceptor differentiation GO:0042490 48 24 4,000 1,62E-07 2,474E-05 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 3,000 2,535E-07 3,643E-05 GO:0010812|negative regulation of cell-substrate adhesion, ! insulin receptor signaling pathway GO:0008286 66 27 4,000 3,038E-07 4,123E-05 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 2,000 1,492E-06 1,918E-04 ! endothelial cell migration GO:0043542 31 17 3,000 1,783E-06 2,178E-04 ! cardiac muscle tissue development GO:0048738 34 17 3,000 1,783E-06 2,074E-04 ! cellular response to insulin stimulus GO:0032869 85 38 4,000 1,801E-06 2E-04 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 3,000 2,283E-06 2,425E-04 ! inositol metabolic process GO:0006020 33 19 3,000 2,879E-06 2,931E-04 ! myoblast cell fate commitment GO:0048625 18 6 2,000 2,972E-06 2,904E-04 ! nuclear migration GO:0007097 13 6 2,000 2,972E-06 2,792E-04 ! positive regulation of pseudopodium assembly GO:0031274 15 6 2,000 2,972E-06 2,689E-04 GO:0031272|regulation of pseudopodium assembly, ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 3,000 4,409E-06 3,847E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 4,000 4,75E-06 4,002E-04 ! negative regulation of cell migration GO:0030336 122 46 4,000 4,75E-06 3,868E-04 ! response to insulin stimulus GO:0032868 98 47 4,000 5,293E-06 4,171E-04 ! regulation of cell-matrix adhesion GO:0001952 81 23 3,000 6,469E-06 4,939E-04 GO:0010810|regulation of cell-substrate adhesion, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 2,000 8,255E-06 6,111E-04 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 8,255E-06 5,931E-04 ! positive regulation of insulin secretion GO:0032024 17 8 2,000 8,255E-06 5,762E-04 ! establishment of nucleus localization GO:0040023 18 8 2,000 8,255E-06 5,602E-04 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 4,000 8,776E-06 5,794E-04 ! myeloid leukocyte differentiation GO:0002573 46 25 3,000 9,164E-06 5,892E-04 ! vasculogenesis GO:0001570 49 25 3,000 9,164E-06 5,741E-04 ! inner ear development GO:0048839 89 53 4,000 9,648E-06 5,893E-04 ! negative regulation of cell motion GO:0051271 142 55 4,000 1,16E-05 6,909E-04 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 2,000 1,233E-05 7,174E-04 ! RNA elongation GO:0006354 90 56 4,000 1,268E-05 7,202E-04 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 3,000 1,465E-05 8,133E-04 ! lipid modification GO:0030258 112 60 4,000 1,781E-05 9,671E-04 ! negative regulation of protein kinase cascade GO:0010741 72 30 3,000 1,944E-05 1,033E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 2,000 2,404E-05 1,249E-03 ! positive regulation of peptide secretion GO:0002793 24 11 2,000 2,404E-05 1,223E-03 ! nucleus localization GO:0051647 22 11 2,000 2,404E-05 1,198E-03 ! protein amino acid autophosphorylation GO:0046777 157 64 4,000 2,444E-05 1,194E-03 ! response to peptide hormone stimulus GO:0043434 129 64 4,000 2,444E-05 1,171E-03 ! ear development GO:0043583 114 66 4,000 2,84E-05 1,334E-03 ! steroid hormone receptor signaling pathway GO:0030518 146 66 4,000 2,84E-05 1,309E-03 ! positive regulation of cellular catabolic process GO:0031331 34 12 2,000 3,192E-05 1,444E-03 ! regulation of cell projection assembly GO:0060491 33 12 2,000 3,192E-05 1,418E-03 ! regulation of hormone metabolic process GO:0032350 28 12 2,000 3,192E-05 1,393E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 4,000 4,05E-05 1,736E-03 ! regulation of monooxygenase activity GO:0032768 35 13 2,000 4,134E-05 1,741E-03 ! negative regulation of cell adhesion GO:0007162 94 37 3,000 4,551E-05 1,884E-03 ! regulation of protein stability GO:0031647 77 38 3,000 5,065E-05 2,062E-03 ! regulation of RNA stability GO:0043487 33 14 2,000 5,24E-05 2,099E-03 ! carbohydrate homeostasis GO:0033500 59 39 3,000 5,62E-05 2,215E-03 GO:0042593|glucose homeostasis, ! phosphoinositide metabolic process GO:0030384 146 77 4,000 5,988E-05 2,322E-03 ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 6,524E-05 2,491E-03 ! establishment or maintenance of cell polarity GO:0007163 96 41 3,000 6,862E-05 2,579E-03 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 4,000 7,633E-05 2,825E-03 ! cellular response to hormone stimulus GO:0032870 182 85 4,000 9,605E-05 3,502E-03 ! filopodium assembly GO:0046847 42 17 2,000 9,674E-05 3,476E-03 ! myoblast differentiation GO:0045445 50 17 2,000 9,674E-05 3,425E-03 ! polyol metabolic process GO:0019751 77 45 3,000 9,929E-05 3,465E-03 ! response to retinoic acid GO:0032526 31 18 2,000 1,156E-04 3,979E-03 ! microspike assembly GO:0030035 46 18 2,000 1,156E-04 3,924E-03 ! positive regulation of cell cycle GO:0045787 96 48 3,000 1,281E-04 4,286E-03 ! positive regulation of hormone secretion GO:0046887 35 19 2,000 1,368E-04 4,515E-03 ! response to vitamin A GO:0033189 32 19 2,000 1,368E-04 4,455E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 2,000 1,603E-04 5,152E-03 ! response to vitamin GO:0033273 36 20 2,000 1,603E-04 5,085E-03 ! pancreas development GO:0031016 40 20 2,000 1,603E-04 5,02E-03 ! peptidyl-serine phosphorylation GO:0018105 44 20 2,000 1,603E-04 4,957E-03 ! estrogen receptor signaling pathway GO:0030520 45 20 2,000 1,603E-04 4,895E-03 ! transcription initiation GO:0006352 171 97 4,000 1,792E-04 5,405E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 4,000 1,88E-04 5,602E-03 ! covalent chromatin modification GO:0016569 115 54 3,000 2,03E-04 5,975E-03 ! regulation of cell shape GO:0008360 142 54 3,000 2,03E-04 5,904E-03 ! hindlimb morphogenesis GO:0035137 47 22 2,000 2,148E-04 6,174E-03 ! positive regulation of intracellular transport GO:0032388 42 22 2,000 2,148E-04 6,102E-03 ! peptidyl-serine modification GO:0018209 50 22 2,000 2,148E-04 6,032E-03 ! response to UV GO:0009411 120 55 3,000 2,18E-04 6,052E-03 ! positive regulation of cell migration GO:0030335 137 58 3,000 2,678E-04 7,352E-03 ! regulation of cellular catabolic process GO:0031329 55 24 2,000 2,801E-04 7,604E-03 ! sex determination GO:0007530 48 24 2,000 2,801E-04 7,52E-03 ! regulation of oxidoreductase activity GO:0051341 48 24 2,000 2,801E-04 7,438E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,813E-04 7,388E-03 ! selenocysteine incorporation GO:0001514 12 5 1,000 2,813E-04 7,31E-03 GO:0006451|translational readthrough, ! glial cell fate commitment GO:0021781 14 5 1,000 2,813E-04 7,233E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 2,813E-04 7,157E-03 ! anagen GO:0042640 7 5 1,000 2,813E-04 7,083E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 2,813E-04 7,011E-03 ! response to food GO:0032094 6 5 1,000 2,813E-04 6,94E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 2,813E-04 6,871E-03 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 1,000 2,813E-04 6,803E-03 ! meiotic chromosome segregation GO:0045132 10 5 1,000 2,813E-04 6,736E-03 ! ATP-dependent chromatin remodeling GO:0043044 10 5 1,000 2,813E-04 6,671E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 2,813E-04 6,607E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 2,813E-04 6,544E-03 ! phospholipid scrambling GO:0017121 8 5 1,000 2,813E-04 6,482E-03 ! establishment of organelle localization GO:0051656 122 59 3,000 2,861E-04 6,533E-03 ! regulation of insulin secretion GO:0050796 42 25 2,000 3,171E-04 7,172E-03 ! interaction with host GO:0051701 66 25 2,000 3,171E-04 7,106E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 2,000 3,57E-04 7,929E-03 ! positive regulation of cell projection organization GO:0031346 66 27 2,000 4,001E-04 8,805E-03 ! positive regulation of cell motion GO:0051272 157 65 3,000 4,152E-04 9,055E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 4,204E-04 9,089E-03 ! establishment of spindle localization GO:0051293 16 6 1,000 4,204E-04 9,009E-03 GO:0051653|spindle localization, ! hair follicle maturation GO:0048820 8 6 1,000 4,204E-04 8,931E-03 ! fat cell differentiation GO:0045444 57 28 2,000 4,463E-04 9,4E-03 ! peptidyl-tyrosine modification GO:0018212 57 28 2,000 4,463E-04 9,319E-03 ! myeloid cell differentiation GO:0030099 126 67 3,000 4,661E-04 9,65E-03 ! regulation of peptide secretion GO:0002791 52 29 2,000 4,959E-04 0,01017995 ! negative regulation of protein complex assembly GO:0031333 68 30 2,000 5,488E-04 0,01117282 ! cytokinesis during cell cycle GO:0033205 14 7 1,000 5,865E-04 0,01184099 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 5,865E-04 0,01174393 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 5,865E-04 0,01164845 ! mRNA stabilization GO:0048255 18 7 1,000 5,865E-04 0,01155451 GO:0043489|RNA stabilization, ! male sex determination GO:0030238 15 7 1,000 5,865E-04 0,01146208 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 5,865E-04 0,01137111 ! transcription from RNA polymerase I promoter GO:0006360 14 7 1,000 5,865E-04 0,01128157 ! metanephros development GO:0001656 81 32 2,000 6,652E-04 0,01269634 ! positive regulation of catabolic process GO:0009896 72 32 2,000 6,652E-04 0,01259791 ! organelle localization GO:0051640 155 74 3,000 6,797E-04 0,01277247 ! cell-matrix adhesion GO:0007160 181 76 3,000 7,516E-04 0,01401611 ! T-helper 1 type immune response GO:0042088 12 8 1,000 7,792E-04 0,01442139 ! ER overload response GO:0006983 13 8 1,000 7,792E-04 0,01431296 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 7,792E-04 0,01420615 ! regulation of vascular permeability GO:0043114 12 8 1,000 7,792E-04 0,01410092 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 7,792E-04 0,01399724 ! regulation of respiratory burst GO:0060263 12 8 1,000 7,792E-04 0,01389507 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 1,000 7,792E-04 0,01379438 ! blastocyst growth GO:0001832 19 8 1,000 7,792E-04 0,01369514 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 7,792E-04 0,01359731 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 2,000 7,963E-04 0,01379652 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 9,983E-04 0,01717541 ! induction of positive chemotaxis GO:0050930 17 9 1,000 9,983E-04 0,0170553 ! regulation of glycolysis GO:0006110 20 9 1,000 9,983E-04 0,01693686 ! microtubule bundle formation GO:0001578 22 9 1,000 9,983E-04 0,01682005 ! regulation of Notch signaling pathway GO:0008593 24 9 1,000 9,983E-04 0,01670485 ! cell-substrate adhesion GO:0031589 189 82 3,000 9,994E-04 0,0166098 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 1,022E-03 0,0168673 ! glycogen metabolic process GO:0005977 63 38 2,000 1,105E-03 0,01811898 ! glucan metabolic process GO:0044042 64 39 2,000 1,192E-03 0,01942176 GO:0006073|cellular glucan metabolic process, ! regulation of developmental growth GO:0048638 16 10 1,000 1,244E-03 0,02011865 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 1,244E-03 0,01998629 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,244E-03 0,01985566 ! lung alveolus development GO:0048286 26 10 1,000 1,244E-03 0,01972673 ! negative regulation of striated muscle development GO:0045843 26 10 1,000 1,244E-03 0,01959946 ! glucan biosynthetic process GO:0009250 14 10 1,000 1,244E-03 0,01947382 GO:0005978|glycogen biosynthetic process, ! motor axon guidance GO:0008045 22 10 1,000 1,244E-03 0,01934978 ! regulation of bone resorption GO:0045124 25 10 1,000 1,244E-03 0,01922732 ! protein heterooligomerization GO:0051291 17 10 1,000 1,244E-03 0,01910639 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 1,244E-03 0,01898697 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,244E-03 0,01886904 ! regulation of hormone secretion GO:0046883 69 41 2,000 1,38E-03 0,02081229 ! mesenchymal cell development GO:0014031 94 41 2,000 1,38E-03 0,02068461 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of intracellular protein transport GO:0033157 86 42 2,000 1,48E-03 0,02205336 ! cytokinesis GO:0000910 84 42 2,000 1,48E-03 0,0219197 ! negative regulation of muscle development GO:0048635 27 11 1,000 1,515E-03 0,02228891 ! blood vessel remodeling GO:0001974 30 11 1,000 1,515E-03 0,02215544 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 1,515E-03 0,02202357 ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 1,515E-03 0,02189325 ! DNA methylation GO:0006306 19 11 1,000 1,515E-03 0,02176447 GO:0006305|DNA alkylation, ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 1,515E-03 0,02163719 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 1,000 1,515E-03 0,02151139 ! regulation of embryonic development GO:0045995 35 11 1,000 1,515E-03 0,02138705 ! regulation of cell adhesion GO:0030155 241 92 3,000 1,532E-03 0,02150783 ! neuron migration GO:0001764 85 43 2,000 1,585E-03 0,02213035 ! regulation of cell morphogenesis GO:0022604 243 93 3,000 1,594E-03 0,02212736 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 1,594E-03 0,02200235 ! energy reserve metabolic process GO:0006112 76 44 2,000 1,695E-03 0,02325814 ! developmental growth GO:0048589 88 45 2,000 1,809E-03 0,02468342 ! virus-host interaction GO:0019048 30 12 1,000 1,811E-03 0,02457974 ! regulation of B cell proliferation GO:0030888 22 12 1,000 1,811E-03 0,02444394 ! regulation of positive chemotaxis GO:0050926 22 12 1,000 1,811E-03 0,02430964 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 1,811E-03 0,0241768 ! entry into host cell GO:0030260 34 12 1,000 1,811E-03 0,0240454 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 27 12 1,000 1,811E-03 0,02391543 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,811E-03 0,02378685 ! T cell homeostasis GO:0043029 28 12 1,000 1,811E-03 0,02365965 ! regulation of leukocyte migration GO:0002685 29 12 1,000 1,811E-03 0,0235338 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 1,811E-03 0,02340928 ! localization within membrane GO:0051668 26 12 1,000 1,811E-03 0,02328607 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 2,000 1,927E-03 0,0246499 ! regulation of gene-specific transcription GO:0032583 102 46 2,000 1,927E-03 0,02452151 ! positive regulation of protein transport GO:0051222 80 46 2,000 1,927E-03 0,02439446 ! leukocyte differentiation GO:0002521 232 98 3,000 1,932E-03 0,02432768 ! skeletal muscle tissue development GO:0007519 223 100 3,000 2,08E-03 0,02605669 GO:0060538|skeletal muscle organ development, ! cartilage condensation GO:0001502 22 13 1,000 2,133E-03 0,02658378 ! plasma membrane organization GO:0007009 27 13 1,000 2,133E-03 0,02644884 ! cellular carbohydrate catabolic process GO:0044275 17 13 1,000 2,133E-03 0,02631526 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 2,133E-03 0,02618302 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! chromatin silencing GO:0006342 29 13 1,000 2,133E-03 0,02605211 ! regulation of mRNA stability GO:0043488 32 13 1,000 2,133E-03 0,02592249 ! positive regulation of DNA binding GO:0043388 83 48 2,000 2,179E-03 0,02634958 ! regulation of gene expression, epigenetic GO:0040029 116 50 2,000 2,45E-03 0,02948111 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 1,000 2,48E-03 0,02969357 GO:0060675|ureteric bud morphogenesis, ! regulation of cell projection organization GO:0031344 135 51 2,000 2,593E-03 0,0308971 ! positive regulation of binding GO:0051099 88 52 2,000 2,741E-03 0,03250236 ! histone modification GO:0016570 104 52 2,000 2,741E-03 0,03234535 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 2,851E-03 0,03348504 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 2,851E-03 0,03332482 ! histone deacetylation GO:0016575 24 15 1,000 2,851E-03 0,03316613 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 2,851E-03 0,03300895 ! lymphocyte homeostasis GO:0002260 33 15 1,000 2,851E-03 0,03285324 ! positive regulation of growth GO:0045927 96 53 2,000 2,894E-03 0,03319037 ! regulation of angiogenesis GO:0045765 125 54 2,000 3,052E-03 0,03484221 ! epithelial tube morphogenesis GO:0060562 114 54 2,000 3,052E-03 0,03468015 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,247E-03 0,03672202 ! embryonic hindlimb morphogenesis GO:0035116 36 16 1,000 3,247E-03 0,0365528 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 3,247E-03 0,03638512 ! DNA replication initiation GO:0006270 28 16 1,000 3,247E-03 0,03621898 ! negative regulation of inflammatory response GO:0050728 24 16 1,000 3,247E-03 0,03605435 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 3,247E-03 0,03589121 ! skeletal muscle fiber development GO:0048741 130 56 2,000 3,384E-03 0,03724325 ! muscle fiber development GO:0048747 131 57 2,000 3,558E-03 0,03898363 ! regulation of intracellular transport GO:0032386 108 57 2,000 3,558E-03 0,0388096 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 3,667E-03 0,03981351 ! embryonic forelimb morphogenesis GO:0035115 31 17 1,000 3,667E-03 0,03963734 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 1,000 3,667E-03 0,03946273 ! regulation of survival gene product expression GO:0045884 38 17 1,000 3,667E-03 0,03928965 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 3,667E-03 0,03911807 GO:0031114|regulation of microtubule depolymerization, ! DNA unwinding during replication GO:0006268 26 17 1,000 3,667E-03 0,038948 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 3,667E-03 0,03877939 ! cellular polysaccharide metabolic process GO:0044264 93 58 2,000 3,738E-03 0,03936139 ! positive regulation of proteolysis GO:0045862 36 18 1,000 4,111E-03 0,04310078 ! epidermis morphogenesis GO:0048730 43 18 1,000 4,111E-03 0,04291659 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 4,111E-03 0,04273397 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 4,111E-03 0,04255289 ! kidney development GO:0001822 133 60 2,000 4,113E-03 0,04239978 ! positive regulation of secretion GO:0051047 110 61 2,000 4,309E-03 0,04423276 ! viral reproductive process GO:0022415 132 62 2,000 4,511E-03 0,04610738 ! negative regulation of defense response GO:0031348 27 19 1,000 4,578E-03 0,04660266 ! pigmentation during development GO:0048066 42 19 1,000 4,578E-03 0,04640929 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 4,578E-03 0,04621752 ! regulation of protein complex assembly GO:0043254 132 63 2,000 4,718E-03 0,0474307 ! regulation of mitosis GO:0007088 112 63 2,000 4,718E-03 0,04723631 GO:0051783|regulation of nuclear division, ! integrin-mediated signaling pathway GO:0007229 160 64 2,000 4,931E-03 0,04916527 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 5,069E-03 0,05034093 ! protein amino acid deacetylation GO:0006476 34 20 1,000 5,069E-03 0,05013713 ! protein amino acid acetylation GO:0006473 41 20 1,000 5,069E-03 0,04993496 ! transcription from RNA polymerase III promoter GO:0006383 46 20 1,000 5,069E-03 0,04973442 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 5,069E-03 0,04953548 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 1,000 5,069E-03 0,04933813 ! apoptotic mitochondrial changes GO:0008637 42 20 1,000 5,069E-03 0,04914234 ! DNA duplex unwinding GO:0032508 30 20 1,000 5,069E-03 0,0489481 GO:0032392|DNA geometric change, ! regulation of lipid metabolic process GO:0019216 132 66 2,000 5,373E-03 0,0516814 ! lipid phosphorylation GO:0046834 43 21 1,000 5,583E-03 0,05348838 ! plasma membrane fusion GO:0045026 33 21 1,000 5,583E-03 0,05327944 ! negative regulation of angiogenesis GO:0016525 49 21 1,000 5,583E-03 0,05307213 ! actin filament-based movement GO:0030048 47 21 1,000 5,583E-03 0,05286642 ! embryonic limb morphogenesis GO:0030326 139 67 2,000 5,603E-03 0,0528534 GO:0035113|embryonic appendage morphogenesis, ! viral reproduction GO:0016032 142 68 2,000 5,839E-03 0,05486625 ! cell projection assembly GO:0030031 138 68 2,000 5,839E-03 0,05465603 ! negative regulation of cell size GO:0045792 144 69 2,000 6,081E-03 0,05670133 ! negative regulation of protein kinase activity GO:0006469 144 69 2,000 6,081E-03 0,05648573 ! urogenital system development GO:0001655 149 69 2,000 6,081E-03 0,05627177 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 6,12E-03 0,05641891 ! ureteric bud development GO:0001657 50 22 1,000 6,12E-03 0,05620681 ! positive regulation of locomotion GO:0040017 44 22 1,000 6,12E-03 0,05599629 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of B cell activation GO:0050871 42 22 1,000 6,12E-03 0,05578735 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 6,12E-03 0,05557996 ! negative regulation of kinase activity GO:0033673 145 70 2,000 6,329E-03 0,05726183 ! germ cell development GO:0007281 133 70 2,000 6,329E-03 0,05705053 ! positive regulation of DNA replication GO:0045740 44 23 1,000 6,679E-03 0,05999141 ! regulation of chemotaxis GO:0050920 45 23 1,000 6,679E-03 0,05977166 ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 6,679E-03 0,05955351 ! cellular response to reactive oxygen species GO:0034614 35 23 1,000 6,679E-03 0,05933696 ! DNA modification GO:0006304 36 23 1,000 6,679E-03 0,05912197 ! appendage morphogenesis GO:0035107 150 72 2,000 6,842E-03 0,06034008 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 151 73 2,000 7,107E-03 0,06245658 GO:0060173|limb development, ! calcium-independent cell-cell adhesion GO:0016338 36 24 1,000 7,261E-03 0,06358019 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 7,261E-03 0,06335312 ! negative regulation of phosphorylation GO:0042326 52 24 1,000 7,261E-03 0,06312767 ! platelet activation GO:0030168 41 24 1,000 7,261E-03 0,06290381 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 7,261E-03 0,06268153 ! negative regulation of transferase activity GO:0051348 155 74 2,000 7,379E-03 0,0634733 ! eye development GO:0001654 155 75 2,000 7,656E-03 0,06563066 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 7,865E-03 0,06718191 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 7,865E-03 0,06694783 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 7,865E-03 0,06671537 ! regulation of behavior GO:0050795 48 25 1,000 7,865E-03 0,06648452 ! leukocyte homeostasis GO:0001776 50 25 1,000 7,865E-03 0,06625527 ! protein tetramerization GO:0051262 57 25 1,000 7,865E-03 0,06602759 ! regulation of catabolic process GO:0009894 173 77 2,000 8,23E-03 0,06885679 ! initiation of viral infection GO:0019059 60 26 1,000 8,491E-03 0,07079356 ! molting cycle process GO:0022404 52 26 1,000 8,491E-03 0,07055276 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 8,491E-03 0,0703136 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 1,000 8,491E-03 0,07007606 GO:0045936|negative regulation of phosphate metabolic process, ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 8,491E-03 0,06984011 ! positive regulation of nuclear division GO:0051785 41 26 1,000 8,491E-03 0,06960575 GO:0045840|positive regulation of mitosis, ! blastocyst development GO:0001824 50 26 1,000 8,491E-03 0,06937295 ! neural tube closure GO:0001843 58 26 1,000 8,491E-03 0,06914171 GO:0060606|tube closure, ! blood coagulation GO:0007596 151 79 2,000 8,828E-03 0,07165393 GO:0050817|coagulation, ! protein oligomerization GO:0051259 149 79 2,000 8,828E-03 0,07141666 ! negative regulation of organelle organization GO:0010639 181 80 2,000 9,137E-03 0,07366799 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 1,000 9,138E-03 0,0734333 ! tube lumen formation GO:0035148 59 27 1,000 9,138E-03 0,07319254 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 9,138E-03 0,07295334 ! cellular response to oxidative stress GO:0034599 43 27 1,000 9,138E-03 0,07271571 ! regulation of chromosome organization GO:0033044 49 27 1,000 9,138E-03 0,07247962 ! muscle cell differentiation GO:0042692 178 81 2,000 9,452E-03 0,07472562 ! response to hypoxia GO:0001666 178 81 2,000 9,452E-03 0,07448457 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 9,806E-03 0,07703234 ! protein amino acid acylation GO:0043543 59 28 1,000 9,806E-03 0,07678544 ! dendrite development GO:0016358 67 28 1,000 9,806E-03 0,07654012 ! response to oxygen levels GO:0070482 183 83 2,000 0,01009981 0,07857907 ! response to nutrient GO:0007584 135 84 2,000 0,01043338 0,08091663 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 0,01049608 0,08114532 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 0,01049608 0,08088934 ! primary neural tube formation GO:0014020 61 29 1,000 0,01049608 0,08063497 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 1,000 0,01049608 0,0803822 ! somitogenesis GO:0001756 52 29 1,000 0,01049608 0,080131 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 0,01049608 0,07988137 ! hemostasis GO:0007599 165 85 2,000 0,01077328 0,0817364 ! acute-phase response GO:0006953 50 30 1,000 0,0112066 0,08476074 ! cell fate determination GO:0001709 64 30 1,000 0,0112066 0,08449913 ! positive regulation of multicellular organism growth GO:0040018 55 30 1,000 0,0112066 0,08423914 ! regulation of B cell activation GO:0050864 55 30 1,000 0,0112066 0,08398073 ! regulation of protein transport GO:0051223 165 87 2,000 0,01147217 0,08570797 GO:0070201|regulation of establishment of protein localization, ! male gonad development GO:0008584 56 31 1,000 0,01193773 0,08891423 ! cellular response to extracellular stimulus GO:0031668 52 31 1,000 0,01193773 0,08864397 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 0,01193773 0,08837536 ! response to heat GO:0009408 54 31 1,000 0,01193773 0,08810836 ! regulation of DNA binding GO:0051101 167 89 2,000 0,01219663 0,0897481 ! tube morphogenesis GO:0035239 194 89 2,000 0,01219663 0,08947858 ! regulation of cell cycle process GO:0010564 161 90 2,000 0,0125685 0,09193065 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 1,000 0,01268923 0,09253667 ! spindle organization GO:0007051 50 32 1,000 0,01268923 0,09226126 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 0,01268923 0,09198749 ! hindbrain development GO:0030902 65 32 1,000 0,01268923 0,09171534 ! gene silencing GO:0016458 71 32 1,000 0,01268923 0,09144479 ! ossification GO:0001503 205 91 2,000 0,01294681 0,09302663 ! bone development GO:0060348 206 92 2,000 0,01333158 0,09551043 ! negative regulation of response to external stimulus GO:0032102 50 33 1,000 0,01346086 0,09615465 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 0,01346086 0,09587431 ! glial cell differentiation GO:0010001 67 34 1,000 0,0142524 0,1012169 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 0,0150636 0,10666779 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,0150636 0,1063595 ! placenta development GO:0001890 53 35 1,000 0,0150636 0,10605299 ! regulation of protein localization GO:0032880 188 97 2,000 0,01535285 0,10777878 ! forebrain development GO:0030900 210 98 2,000 0,01577667 0,1104367 ! regulation of muscle development GO:0048634 82 36 1,000 0,01589425 0,11094185 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,01589425 0,11062577 ! regulation of proteolysis GO:0030162 77 36 1,000 0,01589425 0,1103115 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 0,0167441 0,11588055 ! sister chromatid segregation GO:0000819 65 37 1,000 0,0167441 0,1155532 ! tissue remodeling GO:0048771 78 37 1,000 0,0167441 0,1152277 ! regulation of microtubule-based process GO:0032886 86 37 1,000 0,0167441 0,11490403 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 0,01761293 0,12052772 ! meiosis I GO:0007127 74 38 1,000 0,01761293 0,12019105 ! neural tube formation GO:0001841 79 38 1,000 0,01761293 0,11985626 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,01850052 0,12554662 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! gliogenesis GO:0042063 91 41 1,000 0,02033109 0,13758684 ! embryonic epithelial tube formation GO:0001838 85 41 1,000 0,02033109 0,13720676 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,02223403 0,14963562 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 1,000 0,02223403 0,14922453 ! glucose transport GO:0015758 66 43 1,000 0,02223403 0,1488157 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 1,000 0,02223403 0,1484091 ! development of primary male sexual characteristics GO:0046546 80 43 1,000 0,02223403 0,14800471 ! segmentation GO:0035282 78 43 1,000 0,02223403 0,14760252 ! response to reactive oxygen species GO:0000302 75 44 1,000 0,02321209 0,15367791 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,02321209 0,15326256 ! positive regulation of response to external stimulus GO:0032103 88 44 1,000 0,02321209 0,15284945 ! hexose transport GO:0008645 68 44 1,000 0,02321209 0,15243857 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 102 45 1,000 0,02420761 0,15855009 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 0,02420761 0,15812616 ! induction of apoptosis by intracellular signals GO:0008629 95 45 1,000 0,02420761 0,15770449 ! keratinocyte differentiation GO:0030216 81 45 1,000 0,02420761 0,15728507 ! biopolymer methylation GO:0043414 91 45 1,000 0,02420761 0,15686786 ! polysaccharide biosynthetic process GO:0000271 79 46 1,000 0,02522035 0,16299821 ! pigmentation GO:0043473 103 46 1,000 0,02522035 0,16256814 ! neural tube development GO:0021915 91 47 1,000 0,02625012 0,16876066 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02644469 0,16956529 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02644469 0,1691214 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02644469 0,16867983 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02644469 0,16824056 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02644469 0,16780358 ! neuron fate determination GO:0048664 7 5 0,000 0,02644469 0,16736885 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02644469 0,16693637 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02644469 0,16650613 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02644469 0,16607809 ! polyol transport GO:0015791 12 5 0,000 0,02644469 0,16565225 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02644469 0,16522858 ! response to superoxide GO:0000303 10 5 0,000 0,02644469 0,16480708 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02644469 0,16438773 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02644469 0,1639705 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02644469 0,16355538 ! female meiosis GO:0007143 10 5 0,000 0,02644469 0,16314237 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02644469 0,16273143 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02644469 0,16232255 ! hypothalamus development GO:0021854 9 5 0,000 0,02644469 0,16191573 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02644469 0,16151094 ! cobalt ion transport GO:0006824 11 5 0,000 0,02644469 0,16110817 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02644469 0,1607074 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02644469 0,16030863 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02644469 0,15991182 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02644469 0,15951698 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02644469 0,15912408 GO:0048596|embryonic camera-type eye morphogenesis, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02644469 0,15873311 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02644469 0,15834406 ! transposition GO:0032196 9 5 0,000 0,02644469 0,15795691 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02644469 0,15757165 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,02644469 0,15718826 ! negative chemotaxis GO:0050919 16 5 0,000 0,02644469 0,15680674 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02644469 0,15642706 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02644469 0,15604922 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02644469 0,1556732 ! behavioral response to pain GO:0048266 10 5 0,000 0,02644469 0,15529898 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02644469 0,15492656 ! Notch receptor processing GO:0007220 11 5 0,000 0,02644469 0,15455592 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02644469 0,15418706 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02644469 0,15381994 ! micturition GO:0060073 9 5 0,000 0,02644469 0,15345458 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02644469 0,15309094 ! copulation GO:0007620 9 5 0,000 0,02644469 0,15272902 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02644469 0,15236881 ! bioluminescence GO:0008218 9 5 0,000 0,02644469 0,1520103 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02644469 0,15165347 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02644469 0,15129831 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02644469 0,15094481 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02644469 0,15059295 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02644469 0,15024274 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02644469 0,14989415 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02644469 0,14954717 ! grooming behavior GO:0007625 6 5 0,000 0,02644469 0,14920179 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02644469 0,14885801 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02644469 0,14851581 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02644469 0,14817518 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02644469 0,1478361 ! response to protozoan GO:0001562 13 5 0,000 0,02644469 0,14749858 ! lymph vessel development GO:0001945 10 5 0,000 0,02644469 0,14716259 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02644469 0,14682813 ! endochondral ossification GO:0001958 17 5 0,000 0,02644469 0,14649519 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02644469 0,14616375 ! single strand break repair GO:0000012 8 5 0,000 0,02644469 0,14583381 ! parathyroid gland development GO:0060017 14 5 0,000 0,02644469 0,14550535 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02644469 0,14517837 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02644469 0,14485286 ! cytokine secretion GO:0050663 15 5 0,000 0,02644469 0,14452881 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02644469 0,1442062 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02644469 0,14388503 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02644469 0,14356528 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02644469 0,14324695 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02644469 0,14293004 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02644469 0,14261452 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02644469 0,14230039 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02644469 0,14198764 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,02644469 0,14167626 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02644469 0,14136625 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02644469 0,14105759 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02644469 0,14075028 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02644469 0,1404443 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02644469 0,14013965 ! microvillus organization GO:0032528 8 5 0,000 0,02644469 0,13983631 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,02644469 0,13953429 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02644469 0,13923357 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02644469 0,13893414 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02644469 0,138636 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02644469 0,13833914 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02644469 0,13804354 ! polyol catabolic process GO:0046174 9 5 0,000 0,02644469 0,1377492 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02644469 0,13745612 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02644469 0,13716428 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02644469 0,13687368 ! muscle cell migration GO:0014812 8 5 0,000 0,02644469 0,13658431 ! mitochondrial fission GO:0000266 8 5 0,000 0,02644469 0,13629615 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02644469 0,13600921 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02644469 0,13572348 ! mRNA transcription GO:0009299 10 5 0,000 0,02644469 0,13543894 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02644469 0,1351556 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02644469 0,13487344 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02644469 0,13459245 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02644469 0,13431263 ! monocyte activation GO:0042117 10 5 0,000 0,02644469 0,13403398 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02644469 0,13375647 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02644469 0,13348012 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02644469 0,1332049 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02644469 0,13293082 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02644469 0,13265786 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02644469 0,13238602 ! forebrain neuron development GO:0021884 13 5 0,000 0,02644469 0,13211529 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02644469 0,13184567 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02644469 0,13157714 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02644469 0,13130971 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02644469 0,13104336 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02644469 0,13077809 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02644469 0,13051389 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02644469 0,13025076 ! lipid glycosylation GO:0030259 7 5 0,000 0,02644469 0,12998869 ! nucleobase transport GO:0015851 6 5 0,000 0,02644469 0,12972766 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02644469 0,12946769 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02644469 0,12920875 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02644469 0,12895085 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02644469 0,12869398 ! basic amino acid transport GO:0015802 12 5 0,000 0,02644469 0,12843812 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02644469 0,12818329 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02644469 0,12792946 ! actin nucleation GO:0045010 11 5 0,000 0,02644469 0,12767663 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02644469 0,12742481 ! depurination GO:0045007 5 5 0,000 0,02644469 0,12717397 ! depyrimidination GO:0045008 10 5 0,000 0,02644469 0,12692412 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02644469 0,12667525 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02644469 0,12642735 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02644469 0,12618042 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02644469 0,12593446 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02644469 0,12568945 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02644469 0,12544539 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02644469 0,12520228 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02644469 0,12496011 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02644469 0,12471887 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02644469 0,12447857 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02644469 0,12423919 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02644469 0,12400072 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02644469 0,12376317 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02644469 0,12352653 ! response to arsenic GO:0046685 11 5 0,000 0,02644469 0,1232908 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02644469 0,12305596 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02644469 0,12282201 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02644469 0,12258895 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02644469 0,12235677 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02644469 0,12212548 ! response to mercury ion GO:0046689 8 5 0,000 0,02644469 0,12189505 ! response to cadmium ion GO:0046686 7 5 0,000 0,02644469 0,12166549 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02644469 0,1214368 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02644469 0,12120896 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02644469 0,12098198 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02644469 0,12075584 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02644469 0,12053055 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02644469 0,1203061 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02644469 0,12008248 ! decidualization GO:0046697 11 5 0,000 0,02644469 0,1198597 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02644469 0,11963773 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02644469 0,11941659 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02644469 0,11919627 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02644469 0,11897675 ! embryonic cleavage GO:0040016 6 5 0,000 0,02644469 0,11875805 ! peroxisome fission GO:0016559 5 5 0,000 0,02644469 0,11854014 ! histone demethylation GO:0016577 13 5 0,000 0,02644469 0,11832303 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02644469 0,11810672 ! mitotic recombination GO:0006312 9 5 0,000 0,02644469 0,1178912 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02644469 0,11767646 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02644469 0,1174625 ! metaphase plate congression GO:0051310 7 5 0,000 0,02644469 0,11724932 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02644469 0,11703691 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02644469 0,11682527 ! enteric nervous system development GO:0048484 8 5 0,000 0,02644469 0,1166144 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02644469 0,11640428 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02644469 0,11619492 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02644469 0,11598631 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02644469 0,11577845 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02644469 0,11557134 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02644469 0,11536496 ! B cell homeostasis GO:0001782 13 5 0,000 0,02644469 0,11515932 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02644469 0,11495441 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02644469 0,11475022 ! metaphase GO:0051323 11 5 0,000 0,02644469 0,11454677 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02644469 0,11434403 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02644469 0,11414201 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02644469 0,1139407 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02644469 0,1137401 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02644469 0,1135402 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02644469 0,11334101 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02644469 0,11314252 ! response to redox state GO:0051775 6 5 0,000 0,02644469 0,11294471 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02644469 0,1127476 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02644469 0,11255118 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02644469 0,11235544 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02644469 0,11216038 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02644469 0,11196599 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02644469 0,11177228 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02644469 0,11157923 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02644469 0,11138686 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02644469 0,11119514 ! striatum development GO:0021756 14 5 0,000 0,02644469 0,11100408 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02644469 0,11081368 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02644469 0,11062393 ! glial cell migration GO:0008347 10 5 0,000 0,02644469 0,11043483 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02644469 0,11024638 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02644469 0,11005856 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02644469 0,10987139 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02644469 0,10968485 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02644469 0,10949894 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02644469 0,10931367 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02644469 0,10912901 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02644469 0,10894499 ! neuroprotection GO:0043526 8 5 0,000 0,02644469 0,10876158 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02644469 0,10857878 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02644469 0,10839661 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02644469 0,10821504 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02644469 0,10803407 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02644469 0,10785372 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02644469 0,10767396 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02644469 0,1074948 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02644469 0,10731624 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02644469 0,10713827 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02644469 0,10696089 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02644469 0,10678409 ! spindle assembly GO:0051225 6 5 0,000 0,02644469 0,10660788 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02644469 0,10643225 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02644469 0,1062572 ! protein palmitoylation GO:0018345 12 5 0,000 0,02644469 0,10608272 ! drug metabolic process GO:0017144 7 5 0,000 0,02644469 0,10590881 ! stem cell division GO:0017145 11 5 0,000 0,02644469 0,10573548 GO:0048103|somatic stem cell division, ! organ regeneration GO:0031100 7 5 0,000 0,02644469 0,10556271 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02644469 0,1053905 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02644469 0,10521885 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,02729671 0,10843228 ! male sex differentiation GO:0046661 93 48 1,000 0,02729671 0,10825625 ! regulation of inflammatory response GO:0050727 84 48 1,000 0,02729671 0,10808079 ! methylation GO:0032259 97 48 1,000 0,02729671 0,10790591 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 0,02835989 0,11192766 ! protein homooligomerization GO:0051260 84 49 1,000 0,02835989 0,11174713 ! epidermal cell differentiation GO:0009913 87 50 1,000 0,02943949 0,11581427 ! viral infectious cycle GO:0019058 104 51 1,000 0,03053527 0,11993195 ! response to temperature stimulus GO:0009266 84 51 1,000 0,03053527 0,11973944 ! Notch signaling pathway GO:0007219 111 52 1,000 0,03164706 0,12390026 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,03164706 0,12370202 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 0,03164706 0,12350441 ! DNA-dependent DNA replication GO:0006261 82 52 1,000 0,03164706 0,12330743 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 0,03164706 0,12311108 ! amino acid activation GO:0043038 98 52 1,000 0,03164706 0,12291536 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03164955 0,12272992 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03164955 0,12253542 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03164955 0,12234153 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03164955 0,12214826 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03164955 0,1219556 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03164955 0,12176354 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03164955 0,12157209 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03164955 0,12138124 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03164955 0,12119099 ! response to oxygen radical GO:0000305 11 6 0,000 0,03164955 0,12100133 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03164955 0,12081226 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03164955 0,12062379 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03164955 0,1204359 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03164955 0,1202486 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03164955 0,12006188 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03164955 0,11987573 ! forebrain regionalization GO:0021871 9 6 0,000 0,03164955 0,11969017 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03164955 0,11950518 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03164955 0,11932075 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03164955 0,1191369 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03164955 0,11895361 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,03164955 0,11877089 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03164955 0,11858873 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03164955 0,11840712 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03164955 0,11822607 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03164955 0,11804557 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03164955 0,11786562 ! malate metabolic process GO:0006108 13 6 0,000 0,03164955 0,11768622 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03164955 0,11750737 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03164955 0,11732906 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03164955 0,11715129 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03164955 0,11697405 ! protein refolding GO:0042026 15 6 0,000 0,03164955 0,11679735 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03164955 0,11662119 ! opsonization GO:0008228 8 6 0,000 0,03164955 0,11644556 ! mating behavior GO:0007617 7 6 0,000 0,03164955 0,11627045 ! erythrocyte maturation GO:0043249 8 6 0,000 0,03164955 0,11609587 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,03164955 0,11592181 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03164955 0,11574828 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,03164955 0,11557526 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,03164955 0,11540276 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03164955 0,11523077 ! response to interferon-gamma GO:0034341 16 6 0,000 0,03164955 0,1150593 ! toxin metabolic process GO:0009404 11 6 0,000 0,03164955 0,11488833 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03164955 0,11471788 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,03164955 0,11454792 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,03164955 0,11437847 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,03164955 0,11420953 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03164955 0,11404107 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03164955 0,11387312 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03164955 0,11370566 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03164955 0,11353869 ! thymic T cell selection GO:0045061 16 6 0,000 0,03164955 0,11337221 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03164955 0,11320622 ! protein lipoylation GO:0009249 10 6 0,000 0,03164955 0,11304071 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03164955 0,11287569 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,03164955 0,11271115 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03164955 0,11254709 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,03164955 0,1123835 ! glutamate catabolic process GO:0006538 12 6 0,000 0,03164955 0,11222039 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03164955 0,11205775 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03164955 0,11189558 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,03164955 0,11173389 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03164955 0,11157265 ! hyperosmotic response GO:0006972 10 6 0,000 0,03164955 0,11141189 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,03164955 0,11125158 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03164955 0,11109174 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03164955 0,11093235 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03164955 0,11077342 ! urea metabolic process GO:0019627 7 6 0,000 0,03164955 0,11061495 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03164955 0,11045693 ! neutrophil activation GO:0042119 7 6 0,000 0,03164955 0,11029936 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03164955 0,11014223 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,03164955 0,10998556 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03164955 0,10982933 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,03164955 0,10967354 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03164955 0,1095182 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03164955 0,10936329 ! neuron apoptosis GO:0051402 15 6 0,000 0,03164955 0,10920883 ! T cell mediated immunity GO:0002456 17 6 0,000 0,03164955 0,10905479 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03164955 0,1089012 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,03164955 0,10874803 ! carnitine transport GO:0015879 10 6 0,000 0,03164955 0,10859529 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03164955 0,10844299 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03164955 0,1082911 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03164955 0,10813965 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,03164955 0,10798862 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,03164955 0,107838 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03164955 0,10768781 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03164955 0,10753804 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,03164955 0,10738868 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,03164955 0,10723973 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03164955 0,1070912 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03164955 0,10694308 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,03164955 0,10679537 ! response to UV-C GO:0010225 14 6 0,000 0,03164955 0,10664807 ! astrocyte development GO:0014002 16 6 0,000 0,03164955 0,10650117 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03164955 0,10635468 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03164955 0,10620858 ! interaction with symbiont GO:0051702 14 6 0,000 0,03164955 0,10606289 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03164955 0,1059176 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03164955 0,10577271 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,03164955 0,10562821 ! response to copper ion GO:0046688 10 6 0,000 0,03164955 0,1054841 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,03164955 0,10534039 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,03164955 0,10519707 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03164955 0,10505414 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,03164955 0,1049116 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03164955 0,10476944 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03164955 0,10462767 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,03164955 0,10448628 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03164955 0,10434528 ! Schwann cell development GO:0014044 15 6 0,000 0,03164955 0,10420465 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03164955 0,1040644 ! response to pheromone GO:0019236 6 6 0,000 0,03164955 0,10392453 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,03164955 0,10378503 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,03164955 0,10364591 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,03164955 0,10350716 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,03164955 0,10336878 ! subpallium development GO:0021544 15 6 0,000 0,03164955 0,10323077 ! neural tube patterning GO:0021532 8 6 0,000 0,03164955 0,10309313 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03164955 0,10295586 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03164955 0,10281895 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03164955 0,1026824 ! G2 phase GO:0051319 16 6 0,000 0,03164955 0,10254622 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03164955 0,1024104 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03164955 0,10227493 ! oxygen homeostasis GO:0032364 10 6 0,000 0,03164955 0,10213983 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03164955 0,10200508 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03164955 0,10187068 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03164955 0,10173664 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03164955 0,10160296 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03164955 0,10146962 ! receptor internalization GO:0031623 11 6 0,000 0,03164955 0,10133663 ! plasminogen activation GO:0031639 9 6 0,000 0,03164955 0,10120399 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,03164955 0,1010717 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03164955 0,10093975 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,03164955 0,10080815 ! protein deubiquitination GO:0016579 16 6 0,000 0,03164955 0,10067689 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,03164955 0,10054597 ! protein destabilization GO:0031648 9 6 0,000 0,03164955 0,10041539 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03164955 0,10028515 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03164955 0,10015524 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03164955 0,10002568 ! regulation of viral transcription GO:0046782 11 6 0,000 0,03164955 0,09989645 ! progesterone metabolic process GO:0042448 12 6 0,000 0,03164955 0,09976755 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,03164955 0,09963898 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,03164955 0,09951074 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03164955 0,09938284 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03164955 0,09925526 ! determination of adult lifespan GO:0008340 17 6 0,000 0,03164955 0,09912801 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,03164955 0,09900109 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03164955 0,09887449 ! neural plate development GO:0001840 9 6 0,000 0,03164955 0,09874821 ! catecholamine transport GO:0051937 9 6 0,000 0,03164955 0,09862226 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,03164955 0,09849662 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03164955 0,09837131 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,03164955 0,09824631 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,03164955 0,09812164 ! maternal placenta development GO:0001893 12 6 0,000 0,03164955 0,09799727 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,03164955 0,09787323 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03164955 0,09774949 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,03164955 0,09762607 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,03164955 0,09750296 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03164955 0,09738016 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03164955 0,09725767 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,03164955 0,09713549 GO:0055081|anion homeostasis, ! chromatin remodeling GO:0006338 122 53 1,000 0,03277464 0,10046228 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 0,03277464 0,10033638 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 1,000 0,03277464 0,10021081 ! regulation of translational initiation GO:0006446 87 54 1,000 0,03391781 0,10357651 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,03391781 0,10344721 GO:0010863|positive regulation of phospholipase C activity, ! membrane fusion GO:0006944 122 54 1,000 0,03391781 0,10331822 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,03507639 0,10671433 ! regulation of multicellular organism growth GO:0040014 90 55 1,000 0,03507639 0,1065816 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,03625016 0,11001137 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,03625016 0,10987488 ! regulation of DNA replication GO:0006275 105 56 1,000 0,03625016 0,10973872 ! tRNA transcription GO:0009304 17 7 0,000 0,03682673 0,11134616 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03682673 0,11120853 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03682673 0,11107123 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03682673 0,11093428 ! regulation of helicase activity GO:0051095 16 7 0,000 0,03682673 0,11079766 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03682673 0,11066137 ! sleep GO:0030431 16 7 0,000 0,03682673 0,11052543 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03682673 0,11038981 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03682673 0,11025453 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03682673 0,11011958 ! prostate gland development GO:0030850 14 7 0,000 0,03682673 0,10998496 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03682673 0,10985067 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03682673 0,1097167 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03682673 0,10958307 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03682673 0,10944975 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03682673 0,10931676 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03682673 0,1091841 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03682673 0,10905175 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03682673 0,10891973 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03682673 0,10878803 ! glycolipid transport GO:0046836 11 7 0,000 0,03682673 0,10865664 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03682673 0,10852557 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,03682673 0,10839482 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03682673 0,10826438 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03682673 0,10813425 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03682673 0,10800444 ! pericardium development GO:0060039 16 7 0,000 0,03682673 0,10787494 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03682673 0,10774574 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03682673 0,10761686 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03682673 0,10748829 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03682673 0,10736002 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03682673 0,10723206 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03682673 0,1071044 ! lipoprotein transport GO:0042953 14 7 0,000 0,03682673 0,10697705 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03682673 0,10685 ! rhythmic behavior GO:0007622 17 7 0,000 0,03682673 0,10672325 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03682673 0,1065968 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03682673 0,10647065 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03682673 0,1063448 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03682673 0,10621924 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03682673 0,10609398 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03682673 0,10596902 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03682673 0,10584435 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03682673 0,10571997 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03682673 0,10559589 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03682673 0,10547209 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03682673 0,10534859 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03682673 0,10522538 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03682673 0,10510245 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03682673 0,10497981 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03682673 0,10485746 ! spinal cord patterning GO:0021511 14 7 0,000 0,03682673 0,10473539 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03682673 0,1046136 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03682673 0,1044921 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03682673 0,10437088 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03682673 0,10424994 ! adrenal gland development GO:0030325 17 7 0,000 0,03682673 0,10412928 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03682673 0,1040089 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03682673 0,1038888 ! ovulation GO:0030728 10 7 0,000 0,03682673 0,10376897 ! adenohypophysis development GO:0021984 11 7 0,000 0,03682673 0,10364942 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03682673 0,10353015 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03682673 0,10341115 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03682673 0,10329242 ! microtubule nucleation GO:0007020 21 7 0,000 0,03682673 0,10317396 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03682673 0,10305578 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03682673 0,10293787 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03682673 0,10282023 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03682673 0,10270285 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03682673 0,10258574 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03682673 0,1024689 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03682673 0,10235233 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03682673 0,10223602 ! galactose metabolic process GO:0006012 13 7 0,000 0,03682673 0,10211997 ! vesicle fusion GO:0006906 20 7 0,000 0,03682673 0,10200419 ! response to dietary excess GO:0002021 8 7 0,000 0,03682673 0,10188867 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03682673 0,10177341 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03682673 0,10165841 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03682673 0,10154368 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03682673 0,1014292 ! organ growth GO:0035265 15 7 0,000 0,03682673 0,10131497 ! nucleoside transport GO:0015858 11 7 0,000 0,03682673 0,10120101 ! nucleoside salvage GO:0043174 11 7 0,000 0,03682673 0,1010873 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03682673 0,10097385 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03682673 0,10086065 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03682673 0,1007477 ! parturition GO:0007567 16 7 0,000 0,03682673 0,10063501 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03682673 0,10052257 ! rRNA modification GO:0000154 14 7 0,000 0,03682673 0,10041038 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03682673 0,10029844 ! spindle checkpoint GO:0031577 16 7 0,000 0,03682673 0,10018675 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,03682673 0,1000753 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03682673 0,09996411 ! monocyte differentiation GO:0030224 16 7 0,000 0,03682673 0,09985316 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03682673 0,09974246 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03682673 0,099632 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03682673 0,09952179 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03682673 0,09941182 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,03682673 0,09930209 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03682673 0,09919261 ! fibrinolysis GO:0042730 11 7 0,000 0,03682673 0,09908337 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 0,000 0,03682673 0,09897436 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03682673 0,0988656 ! eating behavior GO:0042755 8 7 0,000 0,03682673 0,09875708 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03682673 0,09864879 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03682673 0,09854074 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03682673 0,09843293 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03682673 0,09832535 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03682673 0,09821801 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03682673 0,0981109 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03682673 0,09800403 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03682673 0,09789739 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03682673 0,09779098 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03682673 0,0976848 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03682673 0,09757885 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03682673 0,09747313 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03682673 0,09736764 ! histone ubiquitination GO:0016574 9 7 0,000 0,03682673 0,09726238 ! regulation of meiosis GO:0040020 12 7 0,000 0,03682673 0,09715734 GO:0051445|regulation of meiotic cell cycle, ! T cell lineage commitment GO:0002360 16 7 0,000 0,03682673 0,09705253 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03682673 0,09694795 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03682673 0,09684359 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03682673 0,09673946 ! transcription termination GO:0006353 14 7 0,000 0,03682673 0,09663555 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03682673 0,09653186 ! anaphase GO:0051322 18 7 0,000 0,03682673 0,0964284 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03682673 0,09632516 ! axonal fasciculation GO:0007413 19 7 0,000 0,03682673 0,09622214 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03682673 0,09611933 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03682673 0,09601675 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03682673 0,09591439 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03682673 0,09581224 ! diuresis GO:0030146 12 7 0,000 0,03682673 0,09571032 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03682673 0,0956086 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03682673 0,09550711 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03682673 0,09540583 ! antibiotic transport GO:0042891 9 7 0,000 0,03682673 0,09530476 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03682673 0,09520391 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03682673 0,09510327 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03682673 0,09500285 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03682673 0,09490263 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03682673 0,09480263 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03682673 0,09470284 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03682673 0,09460326 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03682673 0,09450388 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03682673 0,09440472 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03682673 0,09430576 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03682673 0,09420701 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03682673 0,09410847 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03682673 0,09401013 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03682673 0,093912 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03682673 0,09381407 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03682673 0,09371635 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03682673 0,09361883 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03682673 0,09352151 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03682673 0,0934244 ! muscle adaptation GO:0043500 13 7 0,000 0,03682673 0,09332749 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03682673 0,09323077 ! retina homeostasis GO:0001895 12 7 0,000 0,03682673 0,09313426 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03682673 0,09303795 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03682673 0,09294184 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03682673 0,09284592 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03682673 0,0927502 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,03743895 0,09419502 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,03743895 0,09409811 ! heart morphogenesis GO:0003007 105 57 1,000 0,03743895 0,0940014 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,03864256 0,09692379 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,03864256 0,09682438 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,03864256 0,09672518 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,04197637 0,10496241 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,04197637 0,10485509 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,04197637 0,10474799 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,04197637 0,1046411 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,04197637 0,10453443 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04197637 0,10442798 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04197637 0,10432175 ! male meiosis GO:0007140 9 8 0,000 0,04197637 0,10421573 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,04197637 0,10410993 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,04197637 0,10400434 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,04197637 0,10389897 ! meiotic prophase I GO:0007128 14 8 0,000 0,04197637 0,1037938 ! response to zinc ion GO:0010043 12 8 0,000 0,04197637 0,10368886 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04197637 0,10358412 ! oligopeptide transport GO:0006857 16 8 0,000 0,04197637 0,1034796 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,04197637 0,10337528 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,04197637 0,10327118 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,04197637 0,10316728 ! signal peptide processing GO:0006465 12 8 0,000 0,04197637 0,1030636 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,04197637 0,10296012 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,04197637 0,10285685 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04197637 0,10275379 ! succinate metabolic process GO:0006105 17 8 0,000 0,04197637 0,10265093 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,04197637 0,10254828 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,04197637 0,10244583 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,04197637 0,10234359 ! estrogen metabolic process GO:0008210 17 8 0,000 0,04197637 0,10224155 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,04197637 0,10213972 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,04197637 0,10203809 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04197637 0,10193666 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04197637 0,10183543 ! reflex GO:0060004 17 8 0,000 0,04197637 0,1017344 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04197637 0,10163358 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,04197637 0,10153295 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,04197637 0,10143252 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04197637 0,10133229 ! pigment granule organization GO:0048753 17 8 0,000 0,04197637 0,10123226 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04197637 0,10113242 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,04197637 0,10103279 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,04197637 0,10093335 ! astrocyte differentiation GO:0048708 19 8 0,000 0,04197637 0,1008341 ! histidine catabolic process GO:0006548 10 8 0,000 0,04197637 0,10073505 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04197637 0,10063619 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,04197637 0,10053753 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,04197637 0,10043906 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,04197637 0,10034078 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,04197637 0,1002427 ! melanin metabolic process GO:0006582 17 8 0,000 0,04197637 0,1001448 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,04197637 0,1000471 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,04197637 0,09994959 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,04197637 0,09985227 ! macrophage activation GO:0042116 13 8 0,000 0,04197637 0,09975514 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04197637 0,09965819 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04197637 0,09956144 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04197637 0,09946487 ! purine salvage GO:0043101 12 8 0,000 0,04197637 0,09936849 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,04197637 0,09927229 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,04197637 0,09917629 ! osteoblast development GO:0002076 17 8 0,000 0,04197637 0,09908046 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,04197637 0,09898483 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,04197637 0,09888937 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,04197637 0,0987941 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,04197637 0,09869902 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04197637 0,09860411 ! response to UV-B GO:0010224 17 8 0,000 0,04197637 0,09850939 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,04197637 0,09841485 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04197637 0,0983205 ! intermediate filament organization GO:0045109 12 8 0,000 0,04197637 0,09822632 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,04197637 0,09813232 ! cellular extravasation GO:0045123 13 8 0,000 0,04197637 0,09803851 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,04197637 0,09794487 ! response to antibiotic GO:0046677 11 8 0,000 0,04197637 0,09785141 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,04197637 0,09775813 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,04197637 0,09766503 ! DNA topological change GO:0006265 12 8 0,000 0,04197637 0,0975721 ! response to tropane GO:0014073 15 8 0,000 0,04197637 0,09747935 GO:0042220|response to cocaine, ! regulation of T cell differentiation in the thymus GO:0033081 14 8 0,000 0,04197637 0,09738678 ! melanosome transport GO:0032402 13 8 0,000 0,04197637 0,09729438 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,04197637 0,09720216 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04197637 0,09711011 ! mast cell activation GO:0045576 14 8 0,000 0,04197637 0,09701824 ! multicellular organismal aging GO:0010259 20 8 0,000 0,04197637 0,09692654 ! gas homeostasis GO:0033483 14 8 0,000 0,04197637 0,09683501 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,04197637 0,09674366 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,04197637 0,09665248 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,04197637 0,09656147 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04197637 0,09647063 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04197637 0,09637996 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04197637 0,09628946 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,04197637 0,09619914 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,04197637 0,09610898 ! intracellular lipid transport GO:0032365 16 8 0,000 0,04197637 0,09601899 ! response to tumor cell GO:0002347 16 8 0,000 0,04197637 0,09592917 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04197637 0,09583951 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,04197637 0,09575003 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04197637 0,09566071 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,04197637 0,09557156 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,04197637 0,09548257 ! hormone catabolic process GO:0042447 17 8 0,000 0,04197637 0,09539375 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,04197637 0,09530509 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,04197637 0,0952166 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,04197637 0,09512827 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,04197637 0,09504011 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04197637 0,09495211 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,04197637 0,09486427 ! adult feeding behavior GO:0008343 10 8 0,000 0,04197637 0,0947766 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,04197637 0,09468908 ! ATP catabolic process GO:0006200 11 8 0,000 0,04197637 0,09460173 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04197637 0,09451454 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04197637 0,09442751 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,04197637 0,09434064 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04197637 0,09425393 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,04197637 0,09416738 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,04197637 0,09408099 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,04197637 0,09399476 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,04197637 0,09390868 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,04197637 0,09382276 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,04197637 0,093737 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04197637 0,0936514 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,04197637 0,09356595 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,04197637 0,09348066 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04197637 0,09339552 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,04197637 0,09331054 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,04197637 0,09322571 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,04197637 0,09314103 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,04197637 0,09305651 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,04197637 0,09297215 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,04234039 0,09369345 ! camera-type eye development GO:0043010 126 61 1,000 0,04234039 0,09360866 ! negative regulation of response to stimulus GO:0048585 106 61 1,000 0,04234039 0,09352403 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,04360138 0,09622238 ! mesoderm development GO:0007498 128 63 1,000 0,04487625 0,09894646 ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,04487625 0,09885724 ! axon extension GO:0048675 16 9 0,000 0,04709863 0,10365941 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,04709863 0,10356611 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,04709863 0,10347298 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04709863 0,10338001 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,04709863 0,10328721 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,04709863 0,10319457 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,04709863 0,10310211 ! reproductive behavior GO:0019098 22 9 0,000 0,04709863 0,1030098 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04709863 0,10291767 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,04709863 0,10282569 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,04709863 0,10273388 ! UTP metabolic process GO:0046051 10 9 0,000 0,04709863 0,10264224 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,04709863 0,10255076 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,04709863 0,10245944 ! artery development GO:0060840 25 9 0,000 0,04709863 0,10236828 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,04709863 0,10227729 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,04709863 0,10218646 ! equilibrioception GO:0050957 20 9 0,000 0,04709863 0,10209579 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,04709863 0,10200528 ! chemosensory behavior GO:0007635 21 9 0,000 0,04709863 0,10191492 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,04709863 0,10182473 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,04709863 0,1017347 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04709863 0,10164483 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,04709863 0,10155512 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,04709863 0,10146556 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,04709863 0,10137617 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,04709863 0,10128693 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04709863 0,10119785 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04709863 0,10110892 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,04709863 0,10102015 ! protein targeting to ER GO:0045047 25 9 0,000 0,04709863 0,10093154 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,04709863 0,10084308 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,04709863 0,10075477 ! T cell selection GO:0045058 27 9 0,000 0,04709863 0,10066662 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,04709863 0,10057863 ! glycine catabolic process GO:0006546 15 9 0,000 0,04709863 0,10049079 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,04709863 0,1004031 ! endosome organization GO:0007032 20 9 0,000 0,04709863 0,10031556 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04709863 0,10022818 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,04709863 0,10014095 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04709863 0,10005387 ! mannose metabolic process GO:0006013 13 9 0,000 0,04709863 0,09996694 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,04709863 0,09988017 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,04709863 0,09979354 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,04709863 0,09970706 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,04709863 0,09962074 ! receptor clustering GO:0043113 20 9 0,000 0,04709863 0,09953456 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,04709863 0,09944853 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04709863 0,09936265 ! retinol metabolic process GO:0042572 20 9 0,000 0,04709863 0,09927692 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,04709863 0,09919134 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,04709863 0,0991059 GO:0007351|tripartite regional subdivision, ! oligodendrocyte development GO:0014003 11 9 0,000 0,04709863 0,09902061 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,04709863 0,09893547 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04709863 0,09885047 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,04709863 0,09876562 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04709863 0,09868092 ! response to amine stimulus GO:0014075 13 9 0,000 0,04709863 0,09859636 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04709863 0,09851194 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,04709863 0,09842767 ! erythrocyte development GO:0048821 17 9 0,000 0,04709863 0,09834355 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04709863 0,09825956 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,04709863 0,09817573 ! renal water homeostasis GO:0003091 15 9 0,000 0,04709863 0,09809203 ! postreplication repair GO:0006301 25 9 0,000 0,04709863 0,09800848 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,04709863 0,09792506 ! icosanoid secretion GO:0032309 15 9 0,000 0,04709863 0,09784179 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04709863 0,09775867 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,04709863 0,09767568 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,04709863 0,09759283 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,04709863 0,09751013 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04709863 0,09742756 ! sterol catabolic process GO:0016127 14 9 0,000 0,04709863 0,09734514 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04709863 0,09726285 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,04709863 0,0971807 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,04709863 0,09709869 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,04709863 0,09701682 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,04709863 0,09693509 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,04709863 0,09685349 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,04709863 0,09677204 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,04709863 0,09669071 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,04709863 0,09660953 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,04709863 0,09652848 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04709863 0,09644757 ! purine base metabolic process GO:0006144 25 9 0,000 0,04709863 0,09636679 ! pigment granule transport GO:0051904 17 9 0,000 0,04709863 0,09628615 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,04709863 0,09620564 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,04709863 0,09612527 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,04709863 0,09604503 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04709863 0,09596493 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,04709863 0,09588496 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,04709863 0,09580512 ! mitochondrion localization GO:0051646 18 9 0,000 0,04709863 0,09572542 ! gonad development GO:0008406 115 66 1,000 0,04878233 0,09906503 ! negative regulation of cell growth GO:0030308 142 67 1,000 0,05011091 0,10167854 ! activation of MAPK activity GO:0000187 124 67 1,000 0,05011091 0,10159416 ! chromosome segregation GO:0007059 127 67 1,000 0,05011091 0,10150992 ! regulation of lipase activity GO:0060191 137 68 1,000 0,05145248 0,10414118 ! adaptive immune response GO:0002250 126 68 1,000 0,05145248 0,10405497 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,05145248 0,10396891 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,05219364 0,10537939 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,05219364 0,10529237 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05219364 0,1052055 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,05219364 0,10511877 ! associative learning GO:0008306 21 10 0,000 0,05219364 0,10503218 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05219364 0,10494573 ! phosphate transport GO:0006817 24 10 0,000 0,05219364 0,10485943 ! cell volume homeostasis GO:0006884 17 10 0,000 0,05219364 0,10477327 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,05219364 0,10468725 ! CTP metabolic process GO:0046036 11 10 0,000 0,05219364 0,10460137 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,05219364 0,10451563 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,05219364 0,10443003 ! GTP metabolic process GO:0046039 11 10 0,000 0,05219364 0,10434457 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,05219364 0,10425925 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,05219364 0,10417407 ! social behavior GO:0035176 29 10 0,000 0,05219364 0,10408903 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,05219364 0,10400413 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,05219364 0,10391937 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,05219364 0,10383474 ! androgen metabolic process GO:0008209 17 10 0,000 0,05219364 0,10375026 ! phospholipid efflux GO:0033700 19 10 0,000 0,05219364 0,10366591 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05219364 0,10358169 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,05219364 0,10349762 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,05219364 0,10341368 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,05219364 0,10332987 ! pathogenesis GO:0009405 17 10 0,000 0,05219364 0,10324621 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05219364 0,10316267 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,05219364 0,10307928 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,05219364 0,10299601 ! endoderm development GO:0007492 18 10 0,000 0,05219364 0,10291289 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,05219364 0,10282989 ! arginine catabolic process GO:0006527 17 10 0,000 0,05219364 0,10274703 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05219364 0,1026643 ! proline metabolic process GO:0006560 13 10 0,000 0,05219364 0,10258171 ! phosphagen metabolic process GO:0006599 17 10 0,000 0,05219364 0,10249925 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,05219364 0,10241692 ! V(D)J recombination GO:0033151 34 10 0,000 0,05219364 0,10233472 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,05219364 0,10225266 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,05219364 0,10217073 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,05219364 0,10208892 ! B cell proliferation GO:0042100 19 10 0,000 0,05219364 0,10200725 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,05219364 0,10192571 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,05219364 0,1018443 ! multicellular organism growth GO:0035264 19 10 0,000 0,05219364 0,10176302 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,05219364 0,10168187 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,05219364 0,10160085 ! ruffle organization GO:0031529 17 10 0,000 0,05219364 0,10151996 ! epithelial cell development GO:0002064 21 10 0,000 0,05219364 0,10143919 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,05219364 0,10135856 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05219364 0,10127805 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,05219364 0,10119767 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,05219364 0,10111742 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,05219364 0,10103729 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,05219364 0,1009573 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,05219364 0,10087743 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05219364 0,10079768 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05219364 0,10071806 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05219364 0,10063857 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,05219364 0,1005592 ! segment specification GO:0007379 15 10 0,000 0,05219364 0,10047996 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,05219364 0,10040084 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 0,000 0,05219364 0,10032185 ! blastoderm segmentation GO:0007350 19 10 0,000 0,05219364 0,10024298 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,05219364 0,10016423 ! response to dsRNA GO:0043331 23 10 0,000 0,05219364 0,10008561 ! DNA ligation GO:0006266 18 10 0,000 0,05219364 0,10000711 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,05219364 0,09992873 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,05219364 0,09985048 ! melanosome localization GO:0032400 16 10 0,000 0,05219364 0,09977235 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,05219364 0,09969434 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,05219364 0,09961646 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05219364 0,09953869 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,05219364 0,09946105 ! induction of an organ GO:0001759 17 10 0,000 0,05219364 0,09938353 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,05219364 0,09930613 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,05219364 0,09922884 ! protein sumoylation GO:0016925 17 10 0,000 0,05219364 0,09915168 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,05219364 0,09907464 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05219364 0,09899772 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05219364 0,09892092 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05219364 0,09884424 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,05219364 0,09876767 ! salivary gland development GO:0007431 28 10 0,000 0,05219364 0,09869123 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,05219364 0,0986149 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,05219364 0,09853869 ! midbrain development GO:0030901 14 10 0,000 0,05219364 0,0984626 ! musculoskeletal movement GO:0050881 16 10 0,000 0,05219364 0,09838662 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,05219364 0,09831077 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,05219364 0,09823503 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,05219364 0,0981594 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,05219364 0,0980839 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,05219364 0,09800851 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05219364 0,09793323 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05219364 0,09785807 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,05219364 0,09778303 ! detection of calcium ion GO:0005513 24 10 0,000 0,05219364 0,0977081 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05219364 0,09763328 ! blastocyst formation GO:0001825 18 10 0,000 0,05219364 0,09755858 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,05219364 0,09748399 ! cerebellar cortex development GO:0021695 16 10 0,000 0,05219364 0,09740952 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,05219364 0,09733516 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,05219364 0,09726092 ! response to nicotine GO:0035094 20 10 0,000 0,05219364 0,09718679 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,05219364 0,09711277 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,05280685 0,09817895 ! homeostasis of number of cells GO:0048872 131 69 1,000 0,05280685 0,09810429 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 1,000 0,05280685 0,09802974 ! developmental maturation GO:0021700 128 69 1,000 0,05280685 0,09795531 ! cell redox homeostasis GO:0045454 114 70 1,000 0,05417386 0,10041483 ! carbohydrate transport GO:0008643 114 72 1,000 0,05694509 0,10547147 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,05694509 0,10539156 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,05694509 0,10531178 ! respiratory burst GO:0045730 17 11 0,000 0,05726155 0,10581693 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,05726155 0,10573694 ! neuron fate specification GO:0048665 18 11 0,000 0,05726155 0,10565708 ! telencephalon cell migration GO:0022029 23 11 0,000 0,05726155 0,10557734 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,05726155 0,10549772 ! thyroid gland development GO:0030878 26 11 0,000 0,05726155 0,10541822 ! synapsis GO:0007129 14 11 0,000 0,05726155 0,10533884 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,05726155 0,10525958 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,05726155 0,10518043 ! response to pain GO:0048265 27 11 0,000 0,05726155 0,10510141 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,05726155 0,1050225 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,05726155 0,10494372 ! bone resorption GO:0045453 16 11 0,000 0,05726155 0,10486505 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,05726155 0,1047865 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05726155 0,10470807 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05726155 0,10462975 ! melanocyte differentiation GO:0030318 20 11 0,000 0,05726155 0,10455155 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,05726155 0,10447347 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,05726155 0,1043955 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,05726155 0,10431766 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,05726155 0,10423992 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,05726155 0,10416231 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,05726155 0,1040848 ! UV protection GO:0009650 20 11 0,000 0,05726155 0,10400742 ! adult heart development GO:0007512 16 11 0,000 0,05726155 0,10393015 ! chondrocyte differentiation GO:0002062 27 11 0,000 0,05726155 0,10385299 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05726155 0,10377595 ! macroautophagy GO:0016236 19 11 0,000 0,05726155 0,10369902 ! temperature homeostasis GO:0001659 18 11 0,000 0,05726155 0,1036222 ! behavioral fear response GO:0001662 27 11 0,000 0,05726155 0,1035455 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,05726155 0,10346892 ! negative regulation of ossification GO:0030279 27 11 0,000 0,05726155 0,10339244 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,05726155 0,10331608 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,05726155 0,10323983 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,05726155 0,1031637 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,05726155 0,10308768 ! regulation of organ growth GO:0046620 14 11 0,000 0,05726155 0,10301176 ! pigment granule localization GO:0051875 20 11 0,000 0,05726155 0,10293596 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,05726155 0,10286028 ! vasoconstriction GO:0042310 20 11 0,000 0,05726155 0,1027847 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,05726155 0,10270923 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05726155 0,10263388 ! embryonic axis specification GO:0000578 19 11 0,000 0,05726155 0,10255863 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,05726155 0,1024835 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05726155 0,10240847 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,05726155 0,10233356 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,05726155 0,10225875 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,05726155 0,10218406 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,05726155 0,10210947 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,05726155 0,10203499 ! prophase GO:0051324 17 11 0,000 0,05726155 0,10196062 ! neuroblast proliferation GO:0007405 25 11 0,000 0,05726155 0,10188636 ! nucleosome positioning GO:0016584 15 11 0,000 0,05726155 0,10181221 ! regulation of isotype switching GO:0045191 24 11 0,000 0,05726155 0,10173816 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,05726155 0,10166423 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,05726155 0,1015904 ! apical protein localization GO:0045176 18 11 0,000 0,05726155 0,10151667 ! acid secretion GO:0046717 20 11 0,000 0,05726155 0,10144306 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05726155 0,10136955 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,05726155 0,10129614 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,05726155 0,10122285 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,05726155 0,10114966 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,05726155 0,10107657 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,05726155 0,10100359 ! cholesterol efflux GO:0033344 21 11 0,000 0,05726155 0,10093072 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05726155 0,10085795 ! oocyte development GO:0048599 20 11 0,000 0,05726155 0,10078529 ! negative regulation of glucose import GO:0046325 18 11 0,000 0,05726155 0,10071273 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 26 11 0,000 0,05726155 0,10064027 ! embryonic gut development GO:0048566 19 11 0,000 0,05726155 0,10056792 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,05726155 0,10049567 ! activation of innate immune response GO:0002218 16 11 0,000 0,05726155 0,10042353 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,05726155 0,10035149 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,05726155 0,10027955 ! lysogeny GO:0030069 22 11 0,000 0,05726155 0,10020772 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05726155 0,10013599 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,05726155 0,10006436 ! sequestering of metal ion GO:0051238 15 11 0,000 0,05726155 0,09999283 ! acute inflammatory response GO:0002526 118 74 1,000 0,05976482 0,1042896 ! regulation of caspase activity GO:0043281 136 74 1,000 0,05976482 0,10421516 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,06119244 0,10662848 GO:0090046|regulation of transcription regulator activity, ! reproductive structure development GO:0048608 131 75 1,000 0,06119244 0,10655248 ! axon guidance GO:0007411 162 75 1,000 0,06119244 0,10647659 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,06230251 0,10833098 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,06230251 0,10825393 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,06230251 0,108177 ! mating GO:0007618 17 12 0,000 0,06230251 0,10810017 ! protein complex disassembly GO:0043241 28 12 0,000 0,06230251 0,10802344 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06230251 0,10794683 ! hippocampus development GO:0021766 29 12 0,000 0,06230251 0,10787033 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,06230251 0,10779393 ! T cell proliferation GO:0042098 32 12 0,000 0,06230251 0,10771765 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06230251 0,10764147 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,06230251 0,10756539 ! ventral spinal cord development GO:0021517 25 12 0,000 0,06230251 0,10748943 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,06230251 0,10741357 ! drug transport GO:0015893 16 12 0,000 0,06230251 0,10733782 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,06230251 0,10726218 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,06230251 0,10718664 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,06230251 0,10711121 ! polyamine metabolic process GO:0006595 18 12 0,000 0,06230251 0,10703589 ! focal adhesion formation GO:0048041 37 12 0,000 0,06230251 0,10696067 ! mitotic spindle organization GO:0007052 23 12 0,000 0,06230251 0,10688556 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,06230251 0,10681055 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,06230251 0,10673565 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,06230251 0,10666085 ! lipid digestion GO:0044241 21 12 0,000 0,06230251 0,10658616 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,06230251 0,10651157 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06230251 0,10643709 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,06230251 0,10636271 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,06230251 0,10628843 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06230251 0,10621426 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,06230251 0,10614019 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,06230251 0,10606622 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,06230251 0,10599236 ! snRNA metabolic process GO:0016073 30 12 0,000 0,06230251 0,1059186 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,06230251 0,10584495 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,06230251 0,10577139 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06230251 0,10569794 ! cranial nerve development GO:0021545 23 12 0,000 0,06230251 0,10562459 ! fucose catabolic process GO:0019317 25 12 0,000 0,06230251 0,10555134 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,06230251 0,10547819 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,06230251 0,10540515 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06230251 0,1053322 ! zymogen activation GO:0031638 18 12 0,000 0,06230251 0,10525936 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,06230251 0,10518662 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,06230251 0,10511397 ! oocyte differentiation GO:0009994 21 12 0,000 0,06230251 0,10504143 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,06230251 0,10496899 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,06230251 0,10489665 ! negative regulation of mast cell proliferation GO:0070667 24 12 0,000 0,06230251 0,1048244 GO:0042130|negative regulation of T cell proliferation, ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,06230251 0,10475226 ! defense response to fungus GO:0050832 15 12 0,000 0,06230251 0,10468021 ! developmental induction GO:0031128 22 12 0,000 0,06230251 0,10460827 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,06230251 0,10453642 ! lamellipodium assembly GO:0030032 24 12 0,000 0,06230251 0,10446468 ! response to cold GO:0009409 17 12 0,000 0,06230251 0,10439303 ! establishment of cell polarity GO:0030010 21 12 0,000 0,06230251 0,10432148 ! regulation of synapse organization GO:0050807 18 12 0,000 0,06230251 0,10425002 ! regulation of endopeptidase activity GO:0052548 141 77 1,000 0,0640824 0,1071549 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,0640824 0,1070816 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,06554441 0,10944975 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 1,000 0,06701755 0,11183324 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,06731665 0,11225569 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06731665 0,11217912 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,06731665 0,11210265 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06731665 0,11202628 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06731665 0,11195002 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,06731665 0,11187387 ! peroxisomal transport GO:0043574 28 13 0,000 0,06731665 0,11179781 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,06731665 0,11172186 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,06731665 0,11164602 ! organelle fusion GO:0048284 36 13 0,000 0,06731665 0,11157027 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,06731665 0,11149463 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,06731665 0,11141909 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,06731665 0,11134366 ! endocrine pancreas development GO:0031018 25 13 0,000 0,06731665 0,11126832 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,06731665 0,11119309 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,06731665 0,11111796 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,06731665 0,11104293 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,06731665 0,110968 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,06731665 0,11089318 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06731665 0,11081845 ! methionine metabolic process GO:0006555 31 13 0,000 0,06731665 0,11074383 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,06731665 0,1106693 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,06731665 0,11059488 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,06731665 0,11052055 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,06731665 0,11044633 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,06731665 0,1103722 ! cytokine metabolic process GO:0042107 24 13 0,000 0,06731665 0,11029818 ! exocrine system development GO:0035272 34 13 0,000 0,06731665 0,11022425 ! asymmetric protein localization GO:0008105 24 13 0,000 0,06731665 0,11015042 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,06731665 0,1100767 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,06731665 0,11000307 ! L-glutamate transport GO:0015813 30 13 0,000 0,06731665 0,10992953 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,06731665 0,1098561 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,06731665 0,10978277 ! protein homotetramerization GO:0051289 24 13 0,000 0,06731665 0,10970953 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,06731665 0,10963639 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,06731665 0,10956335 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,06731665 0,1094904 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,06731665 0,10941755 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,06731665 0,1093448 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06731665 0,10927215 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,06731665 0,10919959 ! histone methylation GO:0016571 29 13 0,000 0,06731665 0,10912713 ! gland morphogenesis GO:0022612 31 13 0,000 0,06731665 0,10905476 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,06731665 0,10898249 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,06731665 0,10891032 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06731665 0,10883824 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,06731665 0,10876626 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,06731665 0,10869437 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,06731665 0,10862258 ! spleen development GO:0048536 24 13 0,000 0,06731665 0,10855088 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,06731665 0,10847928 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,06731665 0,10840777 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,06731665 0,10833635 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,06731665 0,10826503 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06731665 0,1081938 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,06731665 0,10812267 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,06731665 0,10805163 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,06731665 0,10798069 ! insulin secretion GO:0030073 24 13 0,000 0,06731665 0,10790983 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,06731665 0,10783907 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,06731665 0,1077684 ! acrosome reaction GO:0007340 19 13 0,000 0,06731665 0,10769783 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,06731665 0,10762735 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,06731665 0,10755695 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,06850167 0,10937881 ! meiosis GO:0007126 143 81 1,000 0,06999661 0,11169282 GO:0051327|M phase of meiotic cell cycle, ! positive regulation of phosphorylation GO:0042327 149 81 1,000 0,06999661 0,11161992 ! regulation of peptidase activity GO:0052547 150 82 1,000 0,07150221 0,11394644 ! protein import into nucleus GO:0006606 174 82 1,000 0,07150221 0,11387216 ! meiotic cell cycle GO:0051321 144 82 1,000 0,07150221 0,11379798 ! rRNA transcription GO:0009303 28 14 0,000 0,07230412 0,11499933 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,07230412 0,11492451 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,07230412 0,11484979 ! water transport GO:0006833 21 14 0,000 0,07230412 0,11477516 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,07230412 0,11470063 ! non-recombinational repair GO:0000726 29 14 0,000 0,07230412 0,1146262 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,07230412 0,11455186 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,07230412 0,11447762 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,07230412 0,11440348 ! RNA polyadenylation GO:0043631 32 14 0,000 0,07230412 0,11432943 ! lipid localization GO:0010876 32 14 0,000 0,07230412 0,11425548 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,07230412 0,11418163 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 0,000 0,07230412 0,11410787 ! regulated secretory pathway GO:0045055 24 14 0,000 0,07230412 0,1140342 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,07230412 0,11396063 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,07230412 0,11388715 ! arginine metabolic process GO:0006525 21 14 0,000 0,07230412 0,11381377 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,07230412 0,11374049 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,07230412 0,11366729 ! regulation of heart rate GO:0002027 25 14 0,000 0,07230412 0,1135942 ! fear response GO:0042596 34 14 0,000 0,07230412 0,11352119 ! organic alcohol transport GO:0015850 29 14 0,000 0,07230412 0,11344828 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,07230412 0,11337547 ! embryo implantation GO:0007566 30 14 0,000 0,07230412 0,11330274 ! neutral amino acid transport GO:0015804 28 14 0,000 0,07230412 0,11323011 ! bone mineralization GO:0030282 18 14 0,000 0,07230412 0,11315758 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,07230412 0,11308513 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,07230412 0,11301278 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,07230412 0,11294052 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,07230412 0,11286835 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,07230412 0,11279628 ! regulation of cellular pH GO:0030641 27 14 0,000 0,07230412 0,1127243 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,07230412 0,11265241 ! ribosome assembly GO:0042255 18 14 0,000 0,07230412 0,11258061 ! cerebellum development GO:0021549 23 14 0,000 0,07230412 0,1125089 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,07230412 0,11243729 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,07230412 0,11236576 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,07230412 0,11229433 ! response to gamma radiation GO:0010332 30 14 0,000 0,07230412 0,11222298 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,07230412 0,11215173 ! NADP metabolic process GO:0006739 24 14 0,000 0,07230412 0,11208057 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,07230412 0,1120095 ! oxygen transport GO:0015671 22 14 0,000 0,07230412 0,11193851 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07230412 0,11186762 ! male genitalia development GO:0030539 26 14 0,000 0,07230412 0,11179682 ! regulation of axon extension GO:0030516 43 14 0,000 0,07230412 0,11172611 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,07230412 0,11165548 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,07230412 0,11158495 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,07230412 0,1115145 ! response to drug GO:0042493 149 83 1,000 0,07301832 0,11254495 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 1,000 0,07301832 0,11247399 GO:0045937|positive regulation of phosphate metabolic process, ! nuclear import GO:0051170 177 83 1,000 0,07301832 0,11240312 ! regulation of ligase activity GO:0051340 147 84 1,000 0,07454478 0,11468066 ! negative regulation of growth GO:0045926 168 85 1,000 0,07608144 0,11697103 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,07608144 0,11689746 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07726506 0,11864145 ! lactation GO:0007595 30 15 0,000 0,07726506 0,11856693 ! reproductive cellular process GO:0048610 22 15 0,000 0,07726506 0,1184925 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07726506 0,11841816 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,07726506 0,11834392 ! superoxide anion generation GO:0042554 22 15 0,000 0,07726506 0,11826977 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,07726506 0,11819571 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,07726506 0,11812175 ! copper ion transport GO:0006825 22 15 0,000 0,07726506 0,11804788 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,07726506 0,1179741 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,07726506 0,11790041 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,07726506 0,11782681 ! sulfate transport GO:0008272 27 15 0,000 0,07726506 0,11775331 ! response to cAMP GO:0051591 25 15 0,000 0,07726506 0,1176799 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,07726506 0,11760658 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,07726506 0,11753335 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,07726506 0,11746021 ! response to hexose stimulus GO:0009746 25 15 0,000 0,07726506 0,11738716 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,07726506 0,1173142 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,07726506 0,11724134 ! vesicle coating GO:0006901 38 15 0,000 0,07726506 0,11716856 ! regulation of the force of heart contraction GO:0002026 31 15 0,000 0,07726506 0,11709588 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,07726506 0,11702328 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,07726506 0,11695078 ! regulation of exocytosis GO:0017157 26 15 0,000 0,07726506 0,11687836 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,07726506 0,11680604 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,07726506 0,1167338 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,07726506 0,11666165 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,07726506 0,11658959 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,07726506 0,11651763 ! regulation of vasodilation GO:0042312 27 15 0,000 0,07726506 0,11644575 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,07726506 0,11637395 ! water homeostasis GO:0030104 28 15 0,000 0,07726506 0,11630225 ! cofactor transport GO:0051181 30 15 0,000 0,07726506 0,11623064 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07726506 0,11615911 ! muscle maintenance GO:0046716 26 15 0,000 0,07726506 0,11608767 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,07726506 0,11601632 ! intestinal absorption GO:0050892 31 15 0,000 0,07726506 0,11594506 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07726506 0,11587388 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,07726506 0,11580279 ! heme biosynthetic process GO:0006783 33 15 0,000 0,07726506 0,11573179 ! cell killing GO:0001906 32 15 0,000 0,07726506 0,11566088 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,07726506 0,11559005 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,07726506 0,11551931 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,07726506 0,11544866 ! actin filament polymerization GO:0030041 27 15 0,000 0,07726506 0,11537809 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,07726506 0,11530761 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,07762815 0,11577874 GO:0002696|positive regulation of leukocyte activation, ! mitochondrion organization GO:0007005 159 87 1,000 0,07918476 0,1180283 ! nucleosome assembly GO:0006334 126 87 1,000 0,07918476 0,11795633 ! chromatin assembly GO:0031497 128 88 1,000 0,08075113 0,12021633 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,08075113 0,12014312 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,08219961 0,12222377 ! positive regulation of cell size GO:0045793 29 16 0,000 0,08219961 0,12214943 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,08219961 0,12207517 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,08219961 0,12200101 ! bone remodeling GO:0046849 28 16 0,000 0,08219961 0,12192693 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,08219961 0,12185295 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,08219961 0,12177905 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08219961 0,12170525 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,08219961 0,12163153 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,08219961 0,12155791 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,08219961 0,12148437 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,08219961 0,12141092 ! startle response GO:0001964 28 16 0,000 0,08219961 0,12133756 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,08219961 0,12126429 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,08219961 0,1211911 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,08219961 0,12111801 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,08219961 0,121045 ! protein polyubiquitination GO:0000209 41 16 0,000 0,08219961 0,12097208 ! glutamate metabolic process GO:0006536 25 16 0,000 0,08219961 0,12089925 ! pituitary gland development GO:0021983 30 16 0,000 0,08219961 0,12082651 ! response to osmotic stress GO:0006970 27 16 0,000 0,08219961 0,12075385 ! lysosomal transport GO:0007041 31 16 0,000 0,08219961 0,12068129 ! fructose metabolic process GO:0006000 25 16 0,000 0,08219961 0,1206088 ! L-amino acid transport GO:0015807 33 16 0,000 0,08219961 0,12053641 ! stem cell development GO:0048864 46 16 0,000 0,08219961 0,1204641 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08219961 0,12039188 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08219961 0,12031975 ! intermediate filament-based process GO:0045103 36 16 0,000 0,08219961 0,1202477 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,08219961 0,12017574 ! negative regulation of immune response GO:0050777 38 16 0,000 0,08219961 0,12010386 ! axon cargo transport GO:0008088 46 16 0,000 0,08219961 0,12003207 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,08219961 0,11996037 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,08219961 0,11988875 ! neuron recognition GO:0008038 40 16 0,000 0,08219961 0,11981722 ! mRNA splice site selection GO:0006376 44 16 0,000 0,08219961 0,11974577 ! tissue regeneration GO:0042246 27 16 0,000 0,08219961 0,11967441 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,08219961 0,11960313 ! biomineral formation GO:0031214 22 16 0,000 0,08219961 0,11953194 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,08219961 0,11946083 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,08219961 0,11938981 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,08219961 0,11931887 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08219961 0,11924802 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,08219961 0,11917725 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,08219961 0,11910656 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,08219961 0,11903596 ! negative regulation of leukocyte proliferation GO:0070664 32 16 0,000 0,08219961 0,11896544 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,08219961 0,118895 ! peptide hormone processing GO:0016486 27 16 0,000 0,08219961 0,11882465 ! protein localization in nucleus GO:0034504 192 89 1,000 0,08232709 0,11893855 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,08710791 0,12577106 ! metencephalon development GO:0022037 32 17 0,000 0,08710791 0,12569677 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,08710791 0,12562257 ! signal complex assembly GO:0007172 47 17 0,000 0,08710791 0,12554846 ! gene silencing by RNA GO:0031047 38 17 0,000 0,08710791 0,12547443 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,08710791 0,12540049 ! glial cell development GO:0021782 28 17 0,000 0,08710791 0,12532664 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,08710791 0,12525288 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,08710791 0,1251792 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,08710791 0,12510561 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,08710791 0,1250321 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,08710791 0,12495868 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,08710791 0,12488535 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,08710791 0,1248121 ! NAD metabolic process GO:0019674 33 17 0,000 0,08710791 0,12473894 ! membrane budding GO:0006900 42 17 0,000 0,08710791 0,12466587 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,08710791 0,12459288 ! regulation of protein binding GO:0043393 33 17 0,000 0,08710791 0,12451997 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,08710791 0,12444716 ! genitalia development GO:0048806 32 17 0,000 0,08710791 0,12437442 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,08710791 0,12430177 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,08710791 0,12422921 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,08710791 0,12415673 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,08710791 0,12408434 ! neutrophil chemotaxis GO:0030593 29 17 0,000 0,08710791 0,12401203 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,08710791 0,1239398 ! steroid catabolic process GO:0006706 34 17 0,000 0,08710791 0,12386766 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,08710791 0,1237956 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,08710791 0,12372363 ! gas transport GO:0015669 26 17 0,000 0,08710791 0,12365173 ! organic cation transport GO:0015695 32 17 0,000 0,08710791 0,12357993 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,08710791 0,1235082 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,08710791 0,12343656 ! protein-DNA complex assembly GO:0065004 134 92 1,000 0,08711115 0,12336959 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,08872408 0,12558108 GO:0010498|proteasomal protein catabolic process, ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,0903459 0,12780257 ! regulation of defense response GO:0031347 171 95 1,000 0,09197646 0,13003385 ! nucleosome organization GO:0034728 143 95 1,000 0,09197646 0,12995864 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,09197646 0,12988352 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,0919901 0,12982774 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,0919901 0,12975278 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,0919901 0,12967791 ! limbic system development GO:0021761 40 18 0,000 0,0919901 0,12960313 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,0919901 0,12952843 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,0919901 0,12945381 ! adult walking behavior GO:0007628 36 18 0,000 0,0919901 0,12937929 ! patterning of blood vessels GO:0001569 43 18 0,000 0,0919901 0,12930485 ! heart looping GO:0001947 34 18 0,000 0,0919901 0,12923049 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,0919901 0,12915622 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,0919901 0,12908203 ! centrosome cycle GO:0007098 26 18 0,000 0,0919901 0,12900793 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,0919901 0,12893392 ! glycine metabolic process GO:0006544 30 18 0,000 0,0919901 0,12885999 ! glutamine metabolic process GO:0006541 29 18 0,000 0,0919901 0,12878614 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,0919901 0,12871238 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,0919901 0,12863871 ! DNA integration GO:0015074 32 18 0,000 0,0919901 0,12856512 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,0919901 0,12849161 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,0919901 0,12841818 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,0919901 0,12834484 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,0919901 0,12827159 ! neural crest cell migration GO:0001755 41 18 0,000 0,0919901 0,12819841 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,0919901 0,12812533 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,0919901 0,12805232 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,0919901 0,1279794 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,0919901 0,12790656 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,0919901 0,1278338 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,0919901 0,12776113 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,0919901 0,12768853 ! detection of bacterium GO:0016045 22 18 0,000 0,0919901 0,12761603 ! nerve development GO:0021675 34 18 0,000 0,0919901 0,1275436 ! defense response to virus GO:0051607 43 18 0,000 0,0919901 0,12747125 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,0919901 0,12739899 ! sex differentiation GO:0007548 171 96 1,000 0,09361563 0,12957676 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 0,09526327 0,13178265 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,09684632 0,13389675 ! positive regulation of translation GO:0045727 31 19 0,000 0,09684632 0,13382101 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,09684632 0,13374537 ! neuron maturation GO:0042551 46 19 0,000 0,09684632 0,1336698 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,09684632 0,13359433 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,09684632 0,13351894 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,09684632 0,13344363 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,09684632 0,13336841 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,09684632 0,13329327 ! memory GO:0007613 34 19 0,000 0,09684632 0,13321822 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,09684632 0,13314325 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,09684632 0,13306837 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,09684632 0,13299357 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,09684632 0,13291885 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,09684632 0,13284422 ! cerebral cortex development GO:0021987 40 19 0,000 0,09684632 0,13276967 ! heme metabolic process GO:0042168 40 19 0,000 0,09684632 0,13269521 ! neuromuscular junction development GO:0007528 43 19 0,000 0,09684632 0,13262083 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,09684632 0,13254653 ! response to fungus GO:0009620 26 19 0,000 0,09684632 0,13247231 ! peptide cross-linking GO:0018149 39 19 0,000 0,09684632 0,13239818 ! protein export from nucleus GO:0006611 40 19 0,000 0,09684632 0,13232414 ! heart process GO:0003015 32 19 0,000 0,09684632 0,13225017 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,09684632 0,13217629 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,09684632 0,13210249 ! visual learning GO:0008542 38 19 0,000 0,09684632 0,13202877 ! cellular pigmentation GO:0033059 37 19 0,000 0,09684632 0,13195513 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,09684632 0,13188158 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,09684632 0,13180811 ! vitamin transport GO:0051180 31 19 0,000 0,09684632 0,13173472 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,09684632 0,13166141 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,09684632 0,13158818 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,09684632 0,13151504 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,09684632 0,13144197 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,09684632 0,13136899 ! cilium assembly GO:0042384 38 19 0,000 0,09684632 0,13129609 ! peptide hormone secretion GO:0030072 32 19 0,000 0,09684632 0,13122327 ! protein secretion GO:0009306 45 20 0,000 0,1016767 0,13769189 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,1016767 0,13761561 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,1016767 0,13753941 ! positive regulation of ossification GO:0045778 50 20 0,000 0,1016767 0,13746329 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,1016767 0,13738726 ! skin development GO:0043588 42 20 0,000 0,1016767 0,13731131 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,1016767 0,13723545 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,1016767 0,13715967 ! bile acid metabolic process GO:0008206 34 20 0,000 0,1016767 0,13708398 ! response to alkaloid GO:0043279 38 20 0,000 0,1016767 0,13700837 ! retinoid metabolic process GO:0001523 34 20 0,000 0,1016767 0,13693284 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,1016767 0,13685739 ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,1016767 0,13678203 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,1016767 0,13670675 ! body fluid secretion GO:0007589 33 20 0,000 0,1016767 0,13663156 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,1016767 0,13655644 ! peptide secretion GO:0002790 38 20 0,000 0,1016767 0,13648141 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,1016767 0,13640646 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,1016767 0,1363316 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,1016767 0,13625681 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,1016767 0,13618211 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,1016767 0,13610749 ! cell-cell junction organization GO:0045216 43 20 0,000 0,1016767 0,13603295 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,1016767 0,13595849 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,1016767 0,13588412 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,1016767 0,13580982 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,1016767 0,13573561 ! regulation of glucose import GO:0046324 30 20 0,000 0,1016767 0,13566148 GO:0010827|regulation of glucose transport, ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,1016767 0,13558743 ! negative regulation of T cell activation GO:0050868 41 20 0,000 0,1016767 0,13551346 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,1016767 0,13543957 ! negative regulation of translation GO:0017148 32 20 0,000 0,1016767 0,13536576 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,1016767 0,13529203 ! regulation of cell killing GO:0031341 46 21 0,000 0,10648138 0,14160806 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,10648138 0,14153101 ! hormone secretion GO:0046879 39 21 0,000 0,10648138 0,14145405 ! cAMP metabolic process GO:0046058 41 21 0,000 0,10648138 0,14137717 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,10648138 0,14130038 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,10648138 0,14122367 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,10648138 0,14114704 ! ovarian follicle development GO:0001541 39 21 0,000 0,10648138 0,1410705 ! smooth muscle contraction GO:0006939 48 21 0,000 0,10648138 0,14099404 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,10648138 0,14091766 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,10648138 0,14084136 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,10648138 0,14076515 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,10648138 0,14068902 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,10648138 0,14061297 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,10648138 0,14053701 ! sensory perception of pain GO:0019233 33 21 0,000 0,10648138 0,14046112 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,10648138 0,14038532 ! diencephalon development GO:0021536 36 21 0,000 0,10648138 0,1403096 ! collagen fibril organization GO:0030199 62 21 0,000 0,10648138 0,14023396 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,10648138 0,14015841 ! positive regulation of inflammatory response GO:0050729 41 21 0,000 0,10648138 0,14008293 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,10648138 0,14000753 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,10648138 0,13993222 ! collagen catabolic process GO:0030574 29 21 0,000 0,10648138 0,13985699 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,10648138 0,13978184 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,10648138 0,13970677 ! sperm-egg recognition GO:0035036 23 21 0,000 0,10648138 0,13963178 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,10648138 0,13955687 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,11126049 0,1457423 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,11126049 0,14566419 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,11126049 0,14558617 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,11126049 0,14550823 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 59 22 0,000 0,11126049 0,14543038 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,11126049 0,14535261 ! inactivation of MAPK activity GO:0000188 45 22 0,000 0,11126049 0,14527492 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,11126049 0,14519732 ! cellular response to starvation GO:0009267 37 22 0,000 0,11126049 0,1451198 ! vacuolar transport GO:0007034 41 22 0,000 0,11126049 0,14504236 ! central nervous system neuron development GO:0021954 47 22 0,000 0,11126049 0,144965 ! fucose metabolic process GO:0006004 44 22 0,000 0,11126049 0,14488773 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,11126049 0,14481054 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,11126049 0,14473343 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,11126049 0,1446564 ! cell aging GO:0007569 48 22 0,000 0,11126049 0,14457946 ! stem cell differentiation GO:0048863 57 22 0,000 0,11126049 0,14450259 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,11126049 0,14442581 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,11126049 0,14434911 ! cytolysis GO:0019835 27 22 0,000 0,11126049 0,14427249 ! renal system process GO:0003014 42 22 0,000 0,11126049 0,14419596 ! vasodilation GO:0042311 40 22 0,000 0,11126049 0,1441195 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,11126049 0,14404313 ! G1 phase GO:0051318 44 22 0,000 0,11126049 0,14396683 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,11126049 0,14389062 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,11126049 0,14381449 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,11126049 0,14373843 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,11126049 0,14366246 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,11126049 0,14358657 ! sarcomere organization GO:0045214 32 22 0,000 0,11126049 0,14351076 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,11126049 0,14343503 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,11126049 0,14335938 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,11126049 0,14328381 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,11126049 0,14320831 ! gut development GO:0048565 44 22 0,000 0,11126049 0,1431329 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,11126049 0,14305757 ! protein stabilization GO:0050821 41 22 0,000 0,11126049 0,14298231 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,11601418 0,14901295 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,11601418 0,14893465 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,11601418 0,14885643 ! gluconeogenesis GO:0006094 38 23 0,000 0,11601418 0,14877829 ! glycerol metabolic process GO:0006071 40 23 0,000 0,11601418 0,14870023 ! viral genome replication GO:0019079 44 23 0,000 0,11601418 0,14862225 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,11601418 0,14854436 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,11601418 0,14846655 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,11601418 0,14838882 ! regeneration GO:0031099 42 23 0,000 0,11601418 0,14831117 ! axis specification GO:0009798 43 23 0,000 0,11601418 0,1482336 ! visual behavior GO:0007632 46 23 0,000 0,11601418 0,14815611 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,11601418 0,1480787 ! response to ethanol GO:0045471 47 23 0,000 0,11601418 0,14800138 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,11601418 0,14792413 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,11601418 0,14784697 ! peroxisome organization GO:0007031 43 23 0,000 0,11601418 0,14776989 ! lysosome organization GO:0007040 47 23 0,000 0,11601418 0,14769288 ! vesicle targeting GO:0006903 49 23 0,000 0,11601418 0,14761596 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,11601418 0,14753912 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,11601418 0,14746235 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,11601418 0,14738567 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,11601418 0,14730906 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,11601418 0,14723254 ! fatty acid transport GO:0015908 47 23 0,000 0,11601418 0,1471561 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,11601418 0,14707973 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,11601418 0,14700344 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,11601418 0,14692724 ! hormone transport GO:0009914 41 23 0,000 0,11601418 0,14685111 ! cell-cell recognition GO:0009988 28 23 0,000 0,11601418 0,14677506 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,11601418 0,14669909 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,11601418 0,1466232 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,11601418 0,14654738 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,12074257 0,1524414 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,12074257 0,15236266 GO:0016444|somatic cell DNA recombination, ! positive regulation of cell adhesion GO:0045785 61 24 0,000 0,12074257 0,152284 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,12074257 0,15220542 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,12074257 0,15212693 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,12074257 0,15204851 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,12074257 0,15197017 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,12074257 0,15189192 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,12074257 0,15181375 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,12074257 0,15173565 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,12074257 0,15165764 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,12074257 0,15157971 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,12074257 0,15150185 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,12074257 0,15142408 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,12074257 0,15134639 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,12074257 0,15126877 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,12074257 0,15119124 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,12074257 0,15111378 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,12074257 0,15103641 ! membrane depolarization GO:0051899 45 24 0,000 0,12074257 0,15095911 ! pallium development GO:0021543 56 24 0,000 0,12074257 0,1508819 ! oogenesis GO:0048477 44 24 0,000 0,12074257 0,15080476 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,12074257 0,1507277 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,12074257 0,15065072 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,12074257 0,15057382 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,12074257 0,15049699 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,12074257 0,15042025 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,12074257 0,15034358 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,12074257 0,15026699 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,12074257 0,15019048 ! regulation of amine transport GO:0051952 41 24 0,000 0,12074257 0,15011405 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,12544581 0,15588205 ! leukocyte adhesion GO:0007159 55 25 0,000 0,12544581 0,1558028 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,12544581 0,15572363 ! phototransduction GO:0007602 37 25 0,000 0,12544581 0,15564455 ! keratinization GO:0031424 37 25 0,000 0,12544581 0,15556554 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,12544581 0,15548661 ! vacuole organization GO:0007033 49 25 0,000 0,12544581 0,15540776 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,12544581 0,155329 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,12544581 0,15525031 ! receptor metabolic process GO:0043112 53 25 0,000 0,12544581 0,1551717 ! chromosome condensation GO:0030261 48 25 0,000 0,12544581 0,15509317 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,12544581 0,15501473 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,12544581 0,15493636 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,12544581 0,15485807 ! immunoglobulin production GO:0002377 62 25 0,000 0,12544581 0,15477985 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,12544581 0,15470172 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,12544581 0,15462367 ! liver development GO:0001889 55 25 0,000 0,12544581 0,15454569 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,13012402 0,16022831 ! myelination GO:0042552 50 26 0,000 0,13012402 0,16014759 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,13012402 0,16006696 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,13012402 0,1599864 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,13012402 0,15990592 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,13012402 0,15982553 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,13012402 0,15974521 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,13012402 0,15966498 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,13012402 0,15958483 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,13012402 0,15950475 ! digestive system process GO:0022600 49 26 0,000 0,13012402 0,15942476 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,13012402 0,15934485 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,13012402 0,15926502 ! osteoblast differentiation GO:0001649 63 26 0,000 0,13012402 0,15918527 ! neural crest cell development GO:0014032 59 26 0,000 0,13012402 0,15910559 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,13012402 0,159026 ! negative regulation of cell development GO:0010721 83 26 0,000 0,13012402 0,15894649 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,13012402 0,15886705 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,13012402 0,1587877 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,13012402 0,15870843 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,13012402 0,15862923 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,13012402 0,15855011 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,13012402 0,15847107 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,13012402 0,15839212 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,13012402 0,15831323 ! telomere organization GO:0032200 46 26 0,000 0,13012402 0,15823443 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,13012402 0,15815571 ! alditol metabolic process GO:0019400 44 26 0,000 0,13012402 0,15807706 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,13012402 0,1579985 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,13012402 0,15792001 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,13477733 0,16348611 ! embryonic pattern specification GO:0009880 49 27 0,000 0,13477733 0,16340497 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,13477733 0,16332392 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,13477733 0,16324295 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,13477733 0,16316205 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,13477733 0,16308124 ! iron ion transport GO:0006826 65 27 0,000 0,13477733 0,16300051 ! superoxide metabolic process GO:0006801 41 27 0,000 0,13477733 0,16291985 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,13477733 0,16283928 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,13477733 0,16275879 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,13477733 0,16267837 ! response to starvation GO:0042594 47 27 0,000 0,13477733 0,16259804 ! response to toxin GO:0009636 49 27 0,000 0,13477733 0,16251778 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,13477733 0,1624376 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,13477733 0,16235751 ! leukocyte proliferation GO:0070661 59 27 0,000 0,13477733 0,16227749 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 55 27 0,000 0,13477733 0,16219755 ! neuron fate commitment GO:0048663 52 28 0,000 0,13940589 0,16768517 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,13940589 0,16760265 ! vesicle docking GO:0048278 55 28 0,000 0,13940589 0,16752021 ! circadian rhythm GO:0007623 56 28 0,000 0,13940589 0,16743785 ! negative regulation of protein modification process GO:0031400 66 28 0,000 0,13940589 0,16735557 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,13940589 0,16727337 ! sperm motility GO:0030317 37 28 0,000 0,13940589 0,16719125 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,13940589 0,16710921 ! base-excision repair GO:0006284 41 28 0,000 0,13940589 0,16702726 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,13940589 0,16694538 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,13940589 0,16686359 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,13940589 0,16678187 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,13940589 0,16670023 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,13940589 0,16661868 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,13940589 0,1665372 ! glutathione metabolic process GO:0006749 42 28 0,000 0,13940589 0,16645581 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,13940589 0,16637449 ! lipid oxidation GO:0034440 48 28 0,000 0,13940589 0,16629325 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,13940589 0,16621209 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,13940589 0,16613101 ! translational initiation GO:0006413 66 29 0,000 0,14400981 0,17153387 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,14400981 0,17145027 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,14400981 0,17136676 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,14400981 0,17128333 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,14400981 0,17119998 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,14400981 0,17111671 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,14400981 0,17103352 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,14400981 0,17095042 ! synaptogenesis GO:0007416 46 29 0,000 0,14400981 0,17086739 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,14400981 0,17078445 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,14400981 0,17070158 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,14400981 0,1706188 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,14858923 0,17595903 ! phenol metabolic process GO:0018958 56 30 0,000 0,14858923 0,17587378 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,14858923 0,17578861 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,14858923 0,17570353 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,14858923 0,17561852 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,14858923 0,1755336 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,14858923 0,17544876 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,14858923 0,175364 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,14858923 0,17527933 ! myofibril assembly GO:0030239 50 30 0,000 0,14858923 0,17519473 GO:0055002|striated muscle cell development, ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,14858923 0,17511022 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,14858923 0,17502579 ! phospholipid transport GO:0015914 65 30 0,000 0,14858923 0,17494144 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,14858923 0,17485717 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,14858923 0,17477298 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,14858923 0,17468888 ! negative regulation of transcription regulator activity GO:0090048 57 30 0,000 0,14858923 0,17460485 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 0,000 0,14858923 0,17452091 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,14858923 0,17443704 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,15314428 0,17969811 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,15314428 0,17961184 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,15314428 0,17952566 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,15314428 0,17943955 ! cell junction assembly GO:0034329 85 31 0,000 0,15314428 0,17935353 ! regulation of innate immune response GO:0045088 57 31 0,000 0,15314428 0,1792676 ! ovulation cycle process GO:0022602 55 31 0,000 0,15314428 0,17918174 ! peptide transport GO:0015833 60 31 0,000 0,15314428 0,17909597 ! iron ion homeostasis GO:0055072 60 31 0,000 0,15314428 0,17901027 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,15314428 0,17892466 ! detection of light stimulus GO:0009583 44 31 0,000 0,15314428 0,17883914 ! natural killer cell activation GO:0030101 50 31 0,000 0,15314428 0,17875369 ! ensheathment of neurons GO:0007272 64 31 0,000 0,15314428 0,17866832 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 54 31 0,000 0,15314428 0,17858304 ! negative regulation of leukocyte activation GO:0002695 60 31 0,000 0,15314428 0,17849784 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,15314428 0,17841272 ! eye morphogenesis GO:0048592 65 31 0,000 0,15314428 0,17832768 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,15314428 0,17824272 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,15767509 0,18342868 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,15767509 0,18334138 ! collagen metabolic process GO:0032963 49 32 0,000 0,15767509 0,18325416 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,15767509 0,18316702 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,15767509 0,18307996 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,15767509 0,18299299 ! muscle cell development GO:0055001 52 32 0,000 0,15767509 0,18290609 ! mesoderm formation GO:0001707 73 32 0,000 0,15767509 0,18281929 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,15767509 0,18273256 ! ovulation cycle GO:0042698 57 32 0,000 0,15767509 0,18264592 ! peripheral nervous system development GO:0007422 68 32 0,000 0,15767509 0,18255935 ! BMP signaling pathway GO:0030509 71 32 0,000 0,15767509 0,18247287 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,15767509 0,18238648 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,15767509 0,18230016 ! regulation of pH GO:0006885 56 33 0,000 0,16218178 0,18742199 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,16218178 0,18733338 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,16218178 0,18724484 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,16218178 0,1871564 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,16218178 0,18706803 ! response to ionizing radiation GO:0010212 74 33 0,000 0,16218178 0,18697975 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,16218178 0,18689155 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,16218178 0,18680344 ! leukocyte chemotaxis GO:0030595 55 33 0,000 0,16218178 0,18671541 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,16218178 0,18662746 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,16218178 0,18653959 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,16218178 0,18645181 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,16218178 0,18636411 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,16666449 0,19142517 ! post-embryonic development GO:0009791 76 34 0,000 0,16666449 0,19133522 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,16666449 0,19124535 ! cholesterol transport GO:0030301 62 34 0,000 0,16666449 0,19115556 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,16666449 0,19106586 ! spliceosome assembly GO:0000245 75 34 0,000 0,16666449 0,19097624 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,16666449 0,19088671 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,16666449 0,19079726 ! formation of primary germ layer GO:0001704 76 34 0,000 0,16666449 0,19070789 ! cell fate specification GO:0001708 56 34 0,000 0,16666449 0,19061861 ! negative regulation of MAP kinase activity GO:0043407 78 34 0,000 0,16666449 0,19052941 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,16666449 0,19044029 ! adult locomotory behavior GO:0008344 62 34 0,000 0,16666449 0,19035126 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,17112334 0,19535248 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,17112334 0,19526124 ! negative regulation of secretion GO:0051048 68 35 0,000 0,17112334 0,19517008 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,17112334 0,19507901 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,17112334 0,19498802 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,17112334 0,19489712 ! membrane docking GO:0022406 69 35 0,000 0,17112334 0,1948063 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,17112334 0,19471556 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,17112334 0,19462491 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,17112334 0,19453435 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,17112334 0,19444387 ! ceramide metabolic process GO:0006672 72 35 0,000 0,17112334 0,19435347 ! telencephalon development GO:0021537 81 35 0,000 0,17112334 0,19426316 ! sterol transport GO:0015918 63 35 0,000 0,17112334 0,19417293 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,17112334 0,19408278 ! vesicle localization GO:0051648 70 35 0,000 0,17112334 0,19399272 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,17555846 0,19892825 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,17555846 0,19883603 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,17555846 0,19874389 ! negative regulation of DNA binding GO:0043392 67 36 0,000 0,17555846 0,19865183 ! positive regulation of cell development GO:0010720 85 36 0,000 0,17555846 0,19855986 ! protein targeting to membrane GO:0006612 75 36 0,000 0,17555846 0,19846798 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,17555846 0,19837618 ! aerobic respiration GO:0009060 56 36 0,000 0,17555846 0,19828447 ! cytokine production GO:0001816 68 36 0,000 0,17555846 0,19819284 ! embryonic organ development GO:0048568 67 36 0,000 0,17555846 0,1981013 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,17555846 0,19800984 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,17555846 0,19791846 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,17996997 0,20279826 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,17996997 0,20270476 ! odontogenesis GO:0042476 74 37 0,000 0,17996997 0,20261135 ! actomyosin structure organization GO:0031032 68 37 0,000 0,17996997 0,20251802 ! cell junction organization GO:0034330 96 37 0,000 0,17996997 0,20242478 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,17996997 0,20233163 ! female gonad development GO:0008585 71 37 0,000 0,17996997 0,20223856 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,17996997 0,20214557 ! negative regulation of cell activation GO:0050866 69 37 0,000 0,17996997 0,20205268 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,18435799 0,20688405 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,18435799 0,20678906 ! organic anion transport GO:0015711 82 38 0,000 0,18435799 0,20669416 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,18435799 0,20659935 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,18435799 0,20650462 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,18435799 0,20640998 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,18435799 0,20631543 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,18435799 0,20622096 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,18435799 0,20612658 ! spermatid development GO:0007286 69 38 0,000 0,18435799 0,20603229 ! pigment metabolic process GO:0042440 87 38 0,000 0,18435799 0,20593808 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,18872266 0,21071731 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,18872266 0,21062104 ! negative regulation of binding GO:0051100 71 39 0,000 0,18872266 0,21052487 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,18872266 0,21042878 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,18872266 0,21033279 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,18872266 0,21023688 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,18872266 0,21014105 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,18872266 0,21004532 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,18872266 0,20994967 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,1930641 0,21468165 GO:0006956|complement activation, ! mammary gland development GO:0030879 93 40 0,000 0,1930641 0,21458398 ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,1930641 0,2144864 ! learning GO:0007612 82 40 0,000 0,1930641 0,21438891 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,1930641 0,2142915 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,1930641 0,21419419 ! lipid homeostasis GO:0055088 75 40 0,000 0,1930641 0,21409696 ! mismatch repair GO:0006298 58 40 0,000 0,1930641 0,21399982 ! regulation of action potential in neuron GO:0019228 80 40 0,000 0,1930641 0,21390276 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,1930641 0,2138058 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,1930641 0,21370892 ! RNA export from nucleus GO:0006405 61 41 0,000 0,19738243 0,21839007 ! mRNA catabolic process GO:0006402 79 41 0,000 0,19738243 0,2182912 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,19738243 0,21819243 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,19738243 0,21809374 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,19738243 0,21799515 ! feeding behavior GO:0007631 69 41 0,000 0,19738243 0,21789664 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,19738243 0,21779822 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,19738243 0,21769989 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,19738243 0,21760165 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,19738243 0,2175035 ! spermatid differentiation GO:0048515 73 41 0,000 0,19738243 0,21740544 ! RNA modification GO:0009451 64 41 0,000 0,19738243 0,21730746 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,20167776 0,22193638 ! ear morphogenesis GO:0042471 64 42 0,000 0,20167776 0,22183646 ! organic ether metabolic process GO:0018904 59 42 0,000 0,20167776 0,22173662 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,20167776 0,22163687 ! T cell differentiation GO:0030217 93 42 0,000 0,20167776 0,22153722 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,20167776 0,22143765 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,20167776 0,22133817 ! regulation of T cell differentiation GO:0045580 78 42 0,000 0,20167776 0,22123878 ! regulation of protein secretion GO:0050708 77 42 0,000 0,20167776 0,22113948 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,20167776 0,22104027 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,20167776 0,22094115 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,20595023 0,22552058 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,20595023 0,22541954 ! regulation of tube size GO:0035150 76 43 0,000 0,20595023 0,22531859 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,20595023 0,22521773 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,20595023 0,22511696 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,20595023 0,22501629 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,20595023 0,2249157 ! regulation of T cell proliferation GO:0042129 80 43 0,000 0,20595023 0,2248152 ! ion transmembrane transport GO:0034220 79 43 0,000 0,20595023 0,22471479 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,20595023 0,22461447 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,21019996 0,22914703 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,21019996 0,22904482 ! striated muscle contraction GO:0006941 85 44 0,000 0,21019996 0,22894271 ! phagocytosis GO:0006909 105 44 0,000 0,21019996 0,22884068 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,21019996 0,22873875 ! double-strand break repair GO:0006302 85 44 0,000 0,21019996 0,22863691 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,21442705 0,23313097 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,21442705 0,23302727 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! B cell differentiation GO:0030183 124 45 0,000 0,21442705 0,23292365 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,21442705 0,23282013 ! female gamete generation GO:0007292 71 45 0,000 0,21442705 0,2327167 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,21442705 0,23261336 ! maintenance of location in cell GO:0051651 101 45 0,000 0,21442705 0,23251012 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,21863165 0,23696412 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,21863165 0,23685903 ! glycolysis GO:0006096 71 46 0,000 0,21863165 0,23675404 ! leukocyte migration GO:0050900 75 46 0,000 0,21863165 0,23664914 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,21863165 0,23654434 ! cell growth GO:0016049 90 46 0,000 0,21863165 0,23643963 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,22281386 0,24085586 ! positive regulation of defense response GO:0031349 88 48 0,000 0,22697379 0,24524413 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,22697379 0,24513571 ! mitochondrial transport GO:0006839 94 48 0,000 0,22697379 0,24502739 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,22697379 0,24491916 ! cellular component disassembly GO:0022411 89 48 0,000 0,22697379 0,24481103 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,22697379 0,24470299 ! endosome transport GO:0016197 127 48 0,000 0,22697379 0,24459505 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,22697379 0,2444872 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,22697379 0,24437945 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,22697379 0,2442718 ! response to calcium ion GO:0051592 94 49 0,000 0,23111158 0,24861541 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,23111158 0,24850599 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,23111158 0,24839666 ! regulation of lymphocyte differentiation GO:0045619 92 49 0,000 0,23111158 0,24828742 ! JNK cascade GO:0007254 106 49 0,000 0,23111158 0,24817829 ! regulation of action potential GO:0001508 102 50 0,000 0,23522734 0,25248699 ! regulation of ion transport GO:0043269 86 50 0,000 0,23522734 0,25237611 ! induction of apoptosis by extracellular signals GO:0008624 99 50 0,000 0,23522734 0,25226532 ! endocrine system development GO:0035270 109 50 0,000 0,23522734 0,25215463 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,23522734 0,25204403 ! activation of caspase activity GO:0006919 95 50 0,000 0,23522734 0,25193354 ! regulation of ossification GO:0030278 123 50 0,000 0,23522734 0,25182314 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,23522734 0,25171283 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,23522734 0,25160262 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,23522734 0,25149251 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,23932118 0,2557575 ! peptide metabolic process GO:0006518 80 51 0,000 0,23932118 0,25564567 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,23932118 0,25553394 ! negative regulation of immune system process GO:0002683 101 51 0,000 0,23932118 0,2554223 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,24339322 0,25965487 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,24339322 0,25954153 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,24339322 0,25942829 ! excretion GO:0007588 87 52 0,000 0,24339322 0,25931515 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,24339322 0,25920211 ! respiratory electron transport chain GO:0022904 83 53 0,000 0,24744358 0,26340073 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,24744358 0,26328601 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,24744358 0,26317138 ! vesicle organization GO:0016050 127 53 0,000 0,24744358 0,26305686 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,24744358 0,26294244 ! synapse organization GO:0050808 102 53 0,000 0,24744358 0,26282812 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,25147237 0,26699131 ! neuromuscular process GO:0050905 107 54 0,000 0,25147237 0,26687533 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,25147237 0,26675944 ! regulation of muscle contraction GO:0006937 94 54 0,000 0,25147237 0,26664366 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,25147237 0,26652798 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,25147237 0,2664124 ! RNA catabolic process GO:0006401 103 55 0,000 0,2554797 0,27054049 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,2554797 0,27042327 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,2554797 0,27030616 ! cell recognition GO:0008037 98 55 0,000 0,2554797 0,27018914 ! cell maturation GO:0048469 107 55 0,000 0,2554797 0,27007223 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,2554797 0,26995541 ! glucose catabolic process GO:0006007 88 56 0,000 0,25946569 0,27404872 ! chloride transport GO:0006821 102 57 0,000 0,26343046 0,27811608 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,26343046 0,27799594 GO:0010952|positive regulation of peptidase activity, ! nucleotide-excision repair GO:0006289 91 57 0,000 0,26343046 0,27787591 ! regulation of actin filament length GO:0030832 118 58 0,000 0,26737411 0,28191409 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,26737411 0,28179247 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,26737411 0,28167095 ! aging GO:0007568 112 58 0,000 0,26737411 0,28154954 ! gastrulation GO:0007369 122 58 0,000 0,26737411 0,28142824 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,26737411 0,28130704 ! maintenance of location GO:0051235 124 58 0,000 0,26737411 0,28118594 ! nuclear export GO:0051168 110 59 0,000 0,27129675 0,28518845 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,2751985 0,28916556 ! DNA catabolic process GO:0006308 94 60 0,000 0,2751985 0,28904124 ! regulation of endocytosis GO:0030100 104 60 0,000 0,2751985 0,28891703 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,2751985 0,28879293 ! adult behavior GO:0030534 104 60 0,000 0,2751985 0,28866893 ! regulation of cellular component size GO:0032535 125 61 0,000 0,27907947 0,29261422 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,27907947 0,29248869 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,27907947 0,29236327 ! regulation of heart contraction GO:0008016 123 61 0,000 0,27907947 0,29223795 ! proton transport GO:0015992 117 61 0,000 0,27907947 0,29211274 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,28293976 0,29602649 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,28293976 0,29589976 ! tRNA processing GO:0008033 102 62 0,000 0,28293976 0,29577315 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,2867795 0,29965882 ! hydrogen transport GO:0006818 121 64 0,000 0,29059878 0,3035198 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,29059878 0,30339009 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,29439771 0,30722495 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,29439771 0,30709377 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,29439771 0,3069627 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,29439771 0,30683175 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,29439771 0,3067009 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,29817641 0,3105051 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,30193498 0,31428511 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,30193498 0,31415126 ! secondary metabolic process GO:0019748 125 67 0,000 0,30193498 0,31401752 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,30567353 0,31777039 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,30567353 0,31763523 ! hexose catabolic process GO:0019320 113 68 0,000 0,30567353 0,31750018 ! extracellular matrix organization GO:0030198 146 68 0,000 0,30567353 0,31736525 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,30567353 0,31723043 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,30567353 0,31709572 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,30567353 0,31696113 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,30939215 0,32068096 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,30939215 0,32054497 ! single fertilization GO:0007338 83 69 0,000 0,30939215 0,32040908 ! activation of immune response GO:0002253 120 70 0,000 0,31309097 0,32410222 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,31309097 0,32396495 ! cell cycle checkpoint GO:0000075 145 71 0,000 0,31677008 0,32763307 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,31677008 0,32749441 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,31677008 0,32735588 ! actin filament organization GO:0007015 167 72 0,000 0,32042958 0,33099766 ! B cell activation GO:0042113 179 72 0,000 0,32042958 0,33085777 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,32042958 0,33071799 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,32042958 0,33057833 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,32042958 0,33043878 ! humoral immune response GO:0006959 115 73 0,000 0,32406959 0,33405148 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,32406959 0,33391059 ! regulation of immune effector process GO:0002697 156 73 0,000 0,32406959 0,33376982 ! amino acid transport GO:0006865 148 74 0,000 0,32769021 0,33735658 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 0,000 0,32769021 0,33721448 ! transition metal ion transport GO:0000041 143 75 0,000 0,33129153 0,34077693 ! phosphoinositide-mediated signaling GO:0048015 141 75 0,000 0,33129153 0,3406335 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,33129153 0,3404902 ! rhythmic process GO:0048511 142 75 0,000 0,33129153 0,34034701 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,33487366 0,34388245 ! learning or memory GO:0007611 161 76 0,000 0,33487366 0,34373796 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,33487366 0,34359359 ! regulation of blood pressure GO:0008217 134 76 0,000 0,33487366 0,34344935 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,33487366 0,34330522 ! amine catabolic process GO:0009310 136 77 0,000 0,3384367 0,34681244 ! neurotransmitter transport GO:0006836 142 77 0,000 0,3384367 0,34666703 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,3384367 0,34652174 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,3384367 0,34637657 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,3384367 0,34623152 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,34198076 0,34971075 ! antigen processing and presentation GO:0019882 117 78 0,000 0,34198076 0,34956443 ! fertilization GO:0009566 99 78 0,000 0,34198076 0,34941823 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,34550593 0,35287248 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,34550593 0,35272502 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,34550593 0,35257769 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,34550593 0,35243047 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,34901231 0,35585854 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,34901231 0,35571008 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,35941973 0,36616447 ! exocytosis GO:0006887 153 83 0,000 0,35941973 0,36601184 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,35941973 0,36585934 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,35941973 0,36570696 ! inorganic anion transport GO:0015698 156 83 0,000 0,35941973 0,36555471 ! response to metal ion GO:0010038 158 84 0,000 0,36285196 0,36889195 ! T cell activation GO:0042110 189 84 0,000 0,36285196 0,3687385 ! digestion GO:0007586 130 84 0,000 0,36285196 0,36858517 ! negative regulation of transport GO:0051051 164 85 0,000 0,3662659 0,37189842 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,3662659 0,37174391 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,3662659 0,37158953 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,3662659 0,37143528 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,36966164 0,37472339 ! regulation of lyase activity GO:0051339 169 86 0,000 0,36966164 0,37456797 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,37303927 0,37783373 ! alcohol catabolic process GO:0046164 142 87 0,000 0,37303927 0,37767714 ! cellular respiration GO:0045333 143 88 0,000 0,37639891 0,38092068 ! amine biosynthetic process GO:0009309 146 88 0,000 0,37639891 0,38076295 ! sensory perception of smell GO:0007608 117 88 0,000 0,37639891 0,38060535 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,37974063 0,38382555 ! cellular defense response GO:0006968 123 89 0,000 0,37974063 0,38366682 ! regulation of neurological system process GO:0031644 175 89 0,000 0,37974063 0,38350821 ! response to inorganic substance GO:0010035 173 90 0,000 0,38306454 0,38670524 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,38306454 0,38654551 ! positive regulation of protein modification process GO:0031401 156 90 0,000 0,38306454 0,38638591 ! response to unfolded protein GO:0006986 139 90 0,000 0,38306454 0,38622645 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,38637074 0,38939922 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! gland development GO:0048732 220 91 0,000 0,38637074 0,38923864 ! defense response to bacterium GO:0042742 112 91 0,000 0,38637074 0,3890782 ! amine transport GO:0015837 181 93 0,000 0,39293034 0,39552073 ! vitamin metabolic process GO:0006766 153 93 0,000 0,39293034 0,39535783 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,39618393 0,39846741 ! female pregnancy GO:0007565 166 94 0,000 0,39618393 0,39830344 ! sterol metabolic process GO:0016125 166 94 0,000 0,39618393 0,39813959 ! regulation of membrane potential GO:0042391 179 94 0,000 0,39618393 0,39797588 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,39942018 0,40106186 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,39942018 0,40089709 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,39942018 0,40073245 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,39942018 0,40056794 ! response to protein stimulus GO:0051789 158 96 0,000 0,40263918 0,40363049 ! regulation of T cell activation GO:0050863 175 96 0,000 0,40263918 0,40346494 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,40584101 0,4065066 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,40902577 0,40952867 ! mRNA transport GO:0051028 185 100 0,000 0,41534444 0,41568475 ! positive regulation of immune response GO:0050778 175 100 0,000 0,41534444 0,41551452 ! hormone metabolic process GO:0042445 171 100 0,000 0,41534444 0,41534444