pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6474-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! release of cytochrome c from mitochondria GO:0001836 9 8 3,000 3,329E-07 6,135E-04 ! peptidyl-amino acid modification GO:0018193 61 59 6,000 5,708E-07 5,259E-04 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 3,000 5,954E-07 3,658E-04 GO:0060675|ureteric bud morphogenesis, ! apoptotic mitochondrial changes GO:0008637 11 10 3,000 9,86E-07 4,543E-04 ! cell-substrate junction assembly GO:0007044 11 10 3,000 9,86E-07 3,634E-04 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 3,000 1,539E-06 4,729E-04 GO:0032388|positive regulation of intracellular transport, ! apoptotic nuclear changes GO:0030262 11 11 3,000 1,539E-06 4,053E-04 ! hindbrain development GO:0030902 11 11 3,000 1,539E-06 3,547E-04 ! regulation of intracellular protein transport GO:0033157 25 25 4,000 1,819E-06 3,724E-04 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 4,000 2,727E-06 5,026E-04 ! positive regulation of MAP kinase activity GO:0043406 50 49 5,000 3,224E-06 5,401E-04 ! mitochondrial membrane organization GO:0007006 13 13 3,000 3,293E-06 5,058E-04 ! ureteric bud development GO:0001657 13 13 3,000 3,293E-06 4,669E-04 ! developmental growth GO:0048589 28 28 4,000 3,298E-06 4,342E-04 ! branching morphogenesis of a tube GO:0048754 29 29 4,000 3,96E-06 4,865E-04 ! cell fate commitment GO:0045165 52 52 5,000 4,601E-06 5,3E-04 ! regulation of intracellular transport GO:0032386 31 31 4,000 5,591E-06 6,062E-04 ! T cell lineage commitment GO:0002360 5 5 2,000 5,919E-06 6,061E-04 ! insulin receptor signaling pathway GO:0008286 17 15 3,000 6,207E-06 6,02E-04 ! morphogenesis of a branching structure GO:0001763 32 32 4,000 6,584E-06 6,067E-04 ! positive regulation of protein kinase activity GO:0045860 89 86 6,000 7,512E-06 6,593E-04 ! regulation of protein localization GO:0032880 58 57 5,000 7,934E-06 6,646E-04 ! positive regulation of transferase activity GO:0051347 91 88 6,000 8,758E-06 7,018E-04 GO:0033674|positive regulation of kinase activity, ! response to peptide hormone stimulus GO:0043434 36 34 4,000 8,979E-06 6,895E-04 ! cell junction assembly GO:0034329 18 17 3,000 1,068E-05 7,876E-04 ! N-terminal protein amino acid modification GO:0031365 6 6 2,000 1,177E-05 8,34E-04 GO:0018409|peptide or protein amino-terminal blocking, ! ER overload response GO:0006983 6 6 2,000 1,177E-05 8,031E-04 ! focal adhesion formation GO:0048041 7 6 2,000 1,177E-05 7,745E-04 ! negative regulation of T cell proliferation GO:0042130 6 6 2,000 1,177E-05 7,478E-04 GO:0070667|negative regulation of mast cell proliferation, ! peptidyl-serine phosphorylation GO:0018105 6 6 2,000 1,177E-05 7,228E-04 ! tissue morphogenesis GO:0048729 94 93 6,000 1,264E-05 7,516E-04 ! morphogenesis of an epithelium GO:0002009 63 62 5,000 1,3E-05 7,488E-04 GO:0060429|epithelium development, ! urogenital system development GO:0001655 38 38 4,000 1,578E-05 8,811E-04 ! metanephros development GO:0001656 19 19 3,000 1,718E-05 9,312E-04 ! activation of MAPK activity GO:0000187 39 39 4,000 1,798E-05 9,467E-04 ! regulation of MAP kinase activity GO:0043405 67 66 5,000 1,871E-05 9,581E-04 ! digestive system development GO:0055123 7 7 2,000 2,046E-05 1,019E-03 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! negative regulation of lymphocyte proliferation GO:0050672 7 7 2,000 2,046E-05 9,925E-04 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cranial nerve development GO:0021545 7 7 2,000 2,046E-05 9,671E-04 ! response to gamma radiation GO:0010332 8 7 2,000 2,046E-05 9,429E-04 ! negative regulation of T cell activation GO:0050868 7 7 2,000 2,046E-05 9,199E-04 ! nucleus organization GO:0006997 20 20 3,000 2,134E-05 9,362E-04 ! cellular response to insulin stimulus GO:0032869 23 21 3,000 2,619E-05 1,122E-03 ! mitochondrion organization GO:0007005 44 43 4,000 2,928E-05 1,227E-03 ! cell junction organization GO:0034330 23 22 3,000 3,18E-05 1,302E-03 ! T cell homeostasis GO:0043029 8 8 2,000 3,254E-05 1,304E-03 ! peptidyl-serine modification GO:0018209 8 8 2,000 3,254E-05 1,276E-03 ! positive regulation of growth GO:0045927 23 23 3,000 3,825E-05 1,469E-03 ! tube morphogenesis GO:0035239 47 46 4,000 4,089E-05 1,538E-03 ! cellular response to hormone stimulus GO:0032870 48 46 4,000 4,089E-05 1,507E-03 ! mitochondrial transport GO:0006839 24 24 3,000 4,561E-05 1,648E-03 ! glucose homeostasis GO:0042593 24 24 3,000 4,561E-05 1,617E-03 GO:0033500|carbohydrate homeostasis, ! T cell differentiation GO:0030217 24 24 3,000 4,561E-05 1,586E-03 ! epithelial tube morphogenesis GO:0060562 25 24 3,000 4,561E-05 1,557E-03 ! positive regulation of protein import into nucleus GO:0042307 9 9 2,000 4,852E-05 1,626E-03 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 2,000 4,852E-05 1,597E-03 ! defense response to virus GO:0051607 9 9 2,000 4,852E-05 1,569E-03 ! regulation of protein modification process GO:0031399 79 78 5,000 4,886E-05 1,553E-03 ! regulation of gene-specific transcription GO:0032583 25 25 3,000 5,395E-05 1,685E-03 ! gland development GO:0048732 51 49 4,000 5,577E-05 1,713E-03 ! tube development GO:0035295 83 81 5,000 6,053E-05 1,829E-03 ! response to insulin stimulus GO:0032868 28 26 3,000 6,335E-05 1,883E-03 ! interphase of mitotic cell cycle GO:0051329 52 51 4,000 6,781E-05 1,984E-03 GO:0051325|interphase, ! epidermis morphogenesis GO:0048730 10 10 2,000 6,889E-05 1,984E-03 ! cell structure disassembly during apoptosis GO:0006921 10 10 2,000 6,889E-05 1,953E-03 ! lymphocyte homeostasis GO:0002260 10 10 2,000 6,889E-05 1,924E-03 ! nerve development GO:0021675 10 10 2,000 6,889E-05 1,895E-03 ! gut development GO:0048565 10 10 2,000 6,889E-05 1,867E-03 ! response to hypoxia GO:0001666 53 53 4,000 8,176E-05 2,184E-03 ! regulation of protein transport GO:0051223 53 53 4,000 8,176E-05 2,153E-03 GO:0070201|regulation of establishment of protein localization, ! response to oxygen levels GO:0070482 55 54 4,000 8,952E-05 2,324E-03 ! heart development GO:0007507 90 87 5,000 9,051E-05 2,317E-03 ! G1 phase of mitotic cell cycle GO:0000080 12 11 2,000 9,415E-05 2,377E-03 ! regulation of viral genome replication GO:0045069 11 11 2,000 9,415E-05 2,345E-03 ! cellular response to starvation GO:0009267 11 11 2,000 9,415E-05 2,313E-03 ! negative regulation of lymphocyte activation GO:0051250 11 11 2,000 9,415E-05 2,283E-03 ! regulation of gene expression, epigenetic GO:0040029 29 29 3,000 9,874E-05 2,363E-03 ! covalent chromatin modification GO:0016569 29 29 3,000 9,874E-05 2,333E-03 ! positive regulation of protein transport GO:0051222 29 29 3,000 9,874E-05 2,303E-03 ! response to UV GO:0009411 29 29 3,000 9,874E-05 2,275E-03 ! brain development GO:0007420 91 90 5,000 1,094E-04 2,489E-03 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 2,000 1,248E-04 2,804E-03 ! positive regulation of multicellular organism growth GO:0040018 12 12 2,000 1,248E-04 2,77E-03 ! G1 phase GO:0051318 13 12 2,000 1,248E-04 2,737E-03 ! regulation of DNA replication GO:0006275 32 31 3,000 1,291E-04 2,8E-03 ! negative regulation of cell motion GO:0051271 31 31 3,000 1,291E-04 2,768E-03 ! kidney development GO:0001822 32 32 3,000 1,467E-04 3,107E-03 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 4,000 1,609E-04 3,369E-03 ! negative regulation of DNA replication GO:0008156 13 13 2,000 1,612E-04 3,338E-03 ! actin filament bundle formation GO:0051017 13 13 2,000 1,612E-04 3,301E-03 ! cell aging GO:0007569 13 13 2,000 1,612E-04 3,265E-03 ! response to endoplasmic reticulum stress GO:0034976 13 13 2,000 1,612E-04 3,229E-03 ! regulation of viral reproduction GO:0050792 13 13 2,000 1,612E-04 3,195E-03 ! negative regulation of leukocyte activation GO:0002695 13 13 2,000 1,612E-04 3,161E-03 ! regulation of cell-substrate adhesion GO:0010810 14 13 2,000 1,612E-04 3,127E-03 GO:0001952|regulation of cell-matrix adhesion, ! activation of JUN kinase activity GO:0007257 13 13 2,000 1,612E-04 3,095E-03 ! tissue homeostasis GO:0001894 13 13 2,000 1,612E-04 3,063E-03 GO:0048871|multicellular organismal homeostasis, ! protein tetramerization GO:0051262 13 13 2,000 1,612E-04 3,032E-03 ! response to hormone stimulus GO:0009725 102 100 5,000 1,96E-04 3,65E-03 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 5,000 1,96E-04 3,613E-03 ! positive regulation of protein metabolic process GO:0051247 64 64 4,000 2,022E-04 3,689E-03 ! protein amino acid acylation GO:0043543 14 14 2,000 2,039E-04 3,685E-03 ! hair cycle GO:0042633 14 14 2,000 2,039E-04 3,649E-03 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 3,000 2,095E-04 3,712E-03 ! protein import into nucleus, translocation GO:0000060 15 15 2,000 2,533E-04 4,447E-03 ! ER-nuclear signaling pathway GO:0006984 15 15 2,000 2,533E-04 4,405E-03 ! response to starvation GO:0042594 15 15 2,000 2,533E-04 4,364E-03 ! response to ionizing radiation GO:0010212 16 15 2,000 2,533E-04 4,323E-03 ! leukocyte homeostasis GO:0001776 15 15 2,000 2,533E-04 4,284E-03 ! negative regulation of cell activation GO:0050866 15 15 2,000 2,533E-04 4,245E-03 ! response to drug GO:0042493 37 37 3,000 2,609E-04 4,331E-03 ! lung development GO:0030324 38 37 3,000 2,609E-04 4,293E-03 ! regulation of mitotic cell cycle GO:0007346 72 69 4,000 2,884E-04 4,704E-03 ! cell-matrix adhesion GO:0007160 39 38 3,000 2,897E-04 4,684E-03 ! positive regulation of transport GO:0051050 71 70 4,000 3,086E-04 4,945E-03 ! growth GO:0040007 70 70 4,000 3,086E-04 4,902E-03 ! cellular response to nutrient levels GO:0031669 16 16 2,000 3,099E-04 4,882E-03 ! positive regulation of catabolic process GO:0009896 16 16 2,000 3,099E-04 4,84E-03 ! regulation of JUN kinase activity GO:0043506 17 16 2,000 3,099E-04 4,8E-03 GO:0043507|positive regulation of JUN kinase activity, ! response to xenobiotic stimulus GO:0009410 16 16 2,000 3,099E-04 4,76E-03 ! positive regulation of protein modification process GO:0031401 39 39 3,000 3,208E-04 4,886E-03 ! respiratory tube development GO:0030323 40 39 3,000 3,208E-04 4,846E-03 ! respiratory system development GO:0060541 40 39 3,000 3,208E-04 4,806E-03 ! lymphocyte differentiation GO:0030098 39 39 3,000 3,208E-04 4,767E-03 ! protein oligomerization GO:0051259 39 39 3,000 3,208E-04 4,729E-03 ! positive regulation of cell motion GO:0051272 39 39 3,000 3,208E-04 4,692E-03 ! regulation of fibroblast proliferation GO:0048145 17 17 2,000 3,74E-04 5,428E-03 ! positive regulation of cell adhesion GO:0045785 17 17 2,000 3,74E-04 5,386E-03 ! embryonic skeletal system morphogenesis GO:0048704 17 17 2,000 3,74E-04 5,344E-03 ! response to toxin GO:0009636 18 17 2,000 3,74E-04 5,303E-03 ! response to oxidative stress GO:0006979 76 75 4,000 4,259E-04 5,991E-03 ! cell-substrate adhesion GO:0031589 43 42 3,000 4,282E-04 5,979E-03 ! forebrain development GO:0030900 43 42 3,000 4,282E-04 5,934E-03 ! B cell differentiation GO:0030183 18 18 2,000 4,461E-04 6,136E-03 ! cellular response to extracellular stimulus GO:0031668 18 18 2,000 4,461E-04 6,09E-03 ! negative regulation of DNA metabolic process GO:0051053 19 19 2,000 5,265E-04 7,135E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 2,000 5,265E-04 7,083E-03 ! regulation of protein stability GO:0031647 19 19 2,000 5,265E-04 7,032E-03 ! dorsal/ventral pattern formation GO:0009953 19 19 2,000 5,265E-04 6,981E-03 ! regulation of cell motion GO:0051270 79 79 4,000 5,418E-04 7,132E-03 ! Wnt receptor signaling pathway GO:0016055 46 45 3,000 5,592E-04 7,31E-03 ! MAPKKK cascade GO:0000165 82 81 4,000 6,079E-04 7,89E-03 ! regulation of membrane potential GO:0042391 46 46 3,000 6,086E-04 7,844E-03 ! peptidyl-tyrosine modification GO:0018212 21 20 2,000 6,157E-04 7,88E-03 ! regulation of catabolic process GO:0009894 48 47 3,000 6,61E-04 8,401E-03 ! positive regulation of protein ubiquitination GO:0031398 5 5 1,000 7,111E-04 8,977E-03 ! neuron fate specification GO:0048665 5 5 1,000 7,111E-04 8,916E-03 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 7,111E-04 8,856E-03 ! prostate gland development GO:0030850 5 5 1,000 7,111E-04 8,796E-03 ! metencephalon development GO:0022037 5 5 1,000 7,111E-04 8,737E-03 ! forebrain regionalization GO:0021871 5 5 1,000 7,111E-04 8,68E-03 ! 2-oxoglutarate metabolic process GO:0006103 5 5 1,000 7,111E-04 8,623E-03 ! memory GO:0007613 5 5 1,000 7,111E-04 8,566E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 1,000 7,111E-04 8,511E-03 ! fear response GO:0042596 5 5 1,000 7,111E-04 8,456E-03 ! cellular glucose homeostasis GO:0001678 5 5 1,000 7,111E-04 8,401E-03 ! wound healing, spreading of epidermal cells GO:0035313 5 5 1,000 7,111E-04 8,348E-03 ! protein heterooligomerization GO:0051291 5 5 1,000 7,111E-04 8,295E-03 ! response to UV-B GO:0010224 5 5 1,000 7,111E-04 8,243E-03 ! hair follicle maturation GO:0048820 5 5 1,000 7,111E-04 8,191E-03 ! regulation of mitochondrial membrane potential GO:0051881 5 5 1,000 7,111E-04 8,141E-03 ! spinal cord motor neuron differentiation GO:0021522 5 5 1,000 7,111E-04 8,09E-03 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 1,000 7,111E-04 8,041E-03 ! DNA methylation GO:0006306 5 5 1,000 7,111E-04 7,992E-03 GO:0006305|DNA alkylation, ! regulation of DNA replication initiation GO:0030174 5 5 1,000 7,111E-04 7,943E-03 ! peptidyl-lysine modification GO:0018205 5 5 1,000 7,111E-04 7,895E-03 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 7,111E-04 7,848E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 1,000 7,111E-04 7,801E-03 ! oocyte differentiation GO:0009994 5 5 1,000 7,111E-04 7,755E-03 GO:0048599|oocyte development, ! regulation of protein homodimerization activity GO:0043496 6 5 1,000 7,111E-04 7,71E-03 ! spleen development GO:0048536 5 5 1,000 7,111E-04 7,664E-03 ! positive regulation of viral reproduction GO:0048524 5 5 1,000 7,111E-04 7,62E-03 ! ectodermal gut morphogenesis GO:0048567 5 5 1,000 7,111E-04 7,576E-03 GO:0007439|ectodermal gut development, ! embryonic gut development GO:0048566 5 5 1,000 7,111E-04 7,532E-03 ! response to nicotine GO:0035094 5 5 1,000 7,111E-04 7,489E-03 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 2,000 7,139E-04 7,476E-03 ! mammary gland development GO:0030879 23 21 2,000 7,139E-04 7,434E-03 ! DNA integrity checkpoint GO:0031570 21 21 2,000 7,139E-04 7,392E-03 ! regulation of protein import into nucleus GO:0042306 21 21 2,000 7,139E-04 7,351E-03 ! regulation of multicellular organism growth GO:0040014 21 21 2,000 7,139E-04 7,31E-03 ! actin filament organization GO:0007015 50 48 3,000 7,165E-04 7,295E-03 ! regulation of cellular localization GO:0060341 86 85 4,000 7,582E-04 7,678E-03 ! leukocyte differentiation GO:0002521 50 49 3,000 7,752E-04 7,807E-03 ! embryonic skeletal system development GO:0048706 22 22 2,000 8,216E-04 8,23E-03 ! cytokinesis GO:0000910 23 22 2,000 8,216E-04 8,185E-03 ! regulation of DNA metabolic process GO:0051052 51 50 3,000 8,373E-04 8,296E-03 ! T cell activation GO:0042110 51 50 3,000 8,373E-04 8,252E-03 ! anterior/posterior pattern formation GO:0009952 51 50 3,000 8,373E-04 8,208E-03 ! regulation of JNK cascade GO:0046328 25 23 2,000 9,392E-04 9,158E-03 ! response to light stimulus GO:0009416 53 52 3,000 9,718E-04 9,426E-03 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 1,000 1,061E-03 0,01023608 ! virus-host interaction GO:0019048 6 6 1,000 1,061E-03 0,01018277 ! regulation of B cell proliferation GO:0030888 6 6 1,000 1,061E-03 0,01013001 ! regulation of activated T cell proliferation GO:0046006 6 6 1,000 1,061E-03 0,01007779 ! succinate metabolic process GO:0006105 7 6 1,000 1,061E-03 0,01002611 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 1,061E-03 9,975E-03 ! negative regulation of ossification GO:0030279 6 6 1,000 1,061E-03 9,924E-03 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 1,000 1,061E-03 9,874E-03 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 1,061E-03 9,825E-03 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 1,061E-03 9,775E-03 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 1,061E-03 9,727E-03 ! nitric oxide metabolic process GO:0046209 6 6 1,000 1,061E-03 9,679E-03 GO:0006809|nitric oxide biosynthetic process, ! neuroblast proliferation GO:0007405 6 6 1,000 1,061E-03 9,631E-03 ! thymus development GO:0048538 6 6 1,000 1,061E-03 9,584E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 1,061E-03 9,537E-03 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 1,000 1,061E-03 9,491E-03 ! regulation of embryonic development GO:0045995 6 6 1,000 1,061E-03 9,445E-03 ! gliogenesis GO:0042063 24 24 2,000 1,067E-03 9,453E-03 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 2,000 1,067E-03 9,407E-03 ! androgen receptor signaling pathway GO:0030521 24 24 2,000 1,067E-03 9,363E-03 ! regulation of response to stress GO:0080134 97 94 4,000 1,196E-03 0,01045057 ! epidermis development GO:0008544 94 94 4,000 1,196E-03 0,01040127 ! regulation of cell adhesion GO:0030155 56 55 3,000 1,201E-03 0,01039214 ! cellular component disassembly GO:0022411 26 25 2,000 1,205E-03 0,01037699 ! regulation of T cell proliferation GO:0042129 25 25 2,000 1,205E-03 0,01032872 ! negative regulation of immune system process GO:0002683 25 25 2,000 1,205E-03 0,01028091 ! reproductive developmental process GO:0003006 56 56 3,000 1,285E-03 0,01091552 ! negative regulation of cell migration GO:0030336 26 26 2,000 1,354E-03 0,01144541 ! induction of apoptosis by intracellular signals GO:0008629 26 26 2,000 1,354E-03 0,01139315 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 1,000 1,477E-03 0,01237291 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 1,000 1,477E-03 0,01231693 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 1,477E-03 0,01226145 ! hair follicle morphogenesis GO:0031069 7 7 1,000 1,477E-03 0,01220646 ! oxaloacetate metabolic process GO:0006107 7 7 1,000 1,477E-03 0,01215197 ! protein targeting to ER GO:0045047 8 7 1,000 1,477E-03 0,01209796 ! cell differentiation in spinal cord GO:0021515 7 7 1,000 1,477E-03 0,01204443 ! regulation of mRNA processing GO:0050684 7 7 1,000 1,477E-03 0,01199137 ! regulation of skeletal muscle fiber development GO:0048742 7 7 1,000 1,477E-03 0,01193878 ! response to X-ray GO:0010165 7 7 1,000 1,477E-03 0,01188664 ! regulation of intracellular pH GO:0051453 7 7 1,000 1,477E-03 0,01183496 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 1,477E-03 0,01178373 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! alpha-beta T cell differentiation GO:0046632 7 7 1,000 1,477E-03 0,01173294 ! autonomic nervous system development GO:0048483 7 7 1,000 1,477E-03 0,01168258 ! synaptic transmission, cholinergic GO:0007271 7 7 1,000 1,477E-03 0,01163265 ! ectoderm development GO:0007398 99 99 4,000 1,509E-03 0,01183433 ! learning or memory GO:0007611 28 27 2,000 1,514E-03 0,01182188 ! mesenchymal cell development GO:0014031 29 27 2,000 1,514E-03 0,01177199 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! hemopoiesis GO:0030097 104 100 4,000 1,578E-03 0,01222026 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 2,000 1,685E-03 0,01299503 GO:0007254|JNK cascade, ! keratinocyte differentiation GO:0030216 28 28 2,000 1,685E-03 0,01294089 ! histone modification GO:0016570 28 28 2,000 1,685E-03 0,01288719 ! protein amino acid autophosphorylation GO:0046777 28 28 2,000 1,685E-03 0,01283394 ! regulation of mast cell proliferation GO:0070666 28 28 2,000 1,685E-03 0,01278112 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 3,000 1,769E-03 0,01336093 ! positive regulation of cell cycle GO:0045787 29 29 2,000 1,868E-03 0,01405379 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 1,868E-03 0,01399666 ! regulation of lymphocyte proliferation GO:0050670 29 29 2,000 1,868E-03 0,01394 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! regulation of skeletal muscle tissue development GO:0048641 8 8 1,000 1,958E-03 0,01455401 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 1,000 1,958E-03 0,01449556 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 1,958E-03 0,01443758 ! embryonic hindlimb morphogenesis GO:0035116 8 8 1,000 1,958E-03 0,01438006 ! T cell selection GO:0045058 8 8 1,000 1,958E-03 0,014323 ! phosphagen metabolic process GO:0006599 8 8 1,000 1,958E-03 0,01426638 GO:0006600|creatine metabolic process, ! sex determination GO:0007530 8 8 1,000 1,958E-03 0,01421022 ! negative regulation of mitotic cell cycle GO:0045930 9 8 1,000 1,958E-03 0,01415449 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 1,958E-03 0,0140992 ! alpha-beta T cell activation GO:0046631 8 8 1,000 1,958E-03 0,01404434 ! chromatin silencing GO:0006342 8 8 1,000 1,958E-03 0,0139899 ! negative regulation of blood coagulation GO:0030195 9 8 1,000 1,958E-03 0,01393589 ! branched chain family amino acid metabolic process GO:0009081 8 8 1,000 1,958E-03 0,01388229 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 1,958E-03 0,0138291 ! response to reactive oxygen species GO:0000302 31 30 2,000 2,063E-03 0,01451364 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 2,000 2,063E-03 0,01445846 ! skeletal system morphogenesis GO:0048705 31 30 2,000 2,063E-03 0,01440369 ! regulation of ossification GO:0030278 30 30 2,000 2,063E-03 0,01434934 ! positive regulation of cellular component organization GO:0051130 65 65 3,000 2,237E-03 0,01550114 ! B cell activation GO:0042113 31 31 2,000 2,27E-03 0,01567225 ! aging GO:0007568 32 31 2,000 2,27E-03 0,01561377 ! epidermal cell differentiation GO:0009913 31 31 2,000 2,27E-03 0,01555573 ! negative regulation of cell growth GO:0030308 32 32 2,000 2,49E-03 0,01699782 ! negative regulation of cell differentiation GO:0045596 68 67 3,000 2,501E-03 0,01700758 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 2,504E-03 0,01696729 ! response to alkaloid GO:0043279 10 9 1,000 2,504E-03 0,01690514 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 1,000 2,504E-03 0,01684344 ! response to ethanol GO:0045471 9 9 1,000 2,504E-03 0,01678219 ! activation of pro-apoptotic gene products GO:0008633 9 9 1,000 2,504E-03 0,01672139 ! response to osmotic stress GO:0006970 9 9 1,000 2,504E-03 0,01666102 ! cotranslational protein targeting to membrane GO:0006613 10 9 1,000 2,504E-03 0,01660109 ! prostaglandin metabolic process GO:0006693 9 9 1,000 2,504E-03 0,01654159 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 1,000 2,504E-03 0,01648251 ! regulation of cellular pH GO:0030641 9 9 1,000 2,504E-03 0,01642385 ! histone acetylation GO:0016573 9 9 1,000 2,504E-03 0,01636561 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 2,504E-03 0,01630778 ! response to radiation GO:0009314 70 68 3,000 2,64E-03 0,01713418 ! negative regulation of cell size GO:0045792 33 33 2,000 2,723E-03 0,01760629 ! regulation of cellular response to stress GO:0080135 35 33 2,000 2,723E-03 0,01754473 ! regulation of neuron apoptosis GO:0043523 34 33 2,000 2,723E-03 0,01748359 ! regionalization GO:0003002 70 69 3,000 2,785E-03 0,0178224 ! response to nutrient levels GO:0031667 69 69 3,000 2,785E-03 0,01776073 ! wound healing GO:0042060 74 70 3,000 2,935E-03 0,01865334 ! regulation of angiogenesis GO:0045765 35 34 2,000 2,968E-03 0,01879753 ! regulation of bone remodeling GO:0046850 34 34 2,000 2,968E-03 0,01873315 ! regulation of protein catabolic process GO:0042176 35 34 2,000 2,968E-03 0,01866922 ! regulation of cell migration GO:0030334 71 71 3,000 3,091E-03 0,01937462 ! regulation of protein ubiquitination GO:0031396 10 10 1,000 3,113E-03 0,01944792 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 3,113E-03 0,01938222 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 3,113E-03 0,01931696 ! regulation of survival gene product expression GO:0045884 10 10 1,000 3,113E-03 0,01925214 ! induction of apoptosis via death domain receptors GO:0008625 10 10 1,000 3,113E-03 0,01918775 ! protein polyubiquitination GO:0000209 10 10 1,000 3,113E-03 0,01912379 ! neuromuscular junction development GO:0007528 10 10 1,000 3,113E-03 0,01906026 ! regulation of protein binding GO:0043393 11 10 1,000 3,113E-03 0,01899714 ! histone deacetylation GO:0016575 10 10 1,000 3,113E-03 0,01893445 ! gland morphogenesis GO:0022612 10 10 1,000 3,113E-03 0,01887216 ! regulation of erythrocyte differentiation GO:0045646 10 10 1,000 3,113E-03 0,01881029 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 3,113E-03 0,01874882 ! embryonic organ morphogenesis GO:0048562 10 10 1,000 3,113E-03 0,01868774 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 3,113E-03 0,01862707 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 3,113E-03 0,01856679 ! negative regulation of coagulation GO:0050819 11 10 1,000 3,113E-03 0,0185069 ! protein stabilization GO:0050821 10 10 1,000 3,113E-03 0,01844739 ! positive regulation of phosphorylation GO:0042327 35 35 2,000 3,227E-03 0,01905996 ! regulation of tissue remodeling GO:0034103 35 35 2,000 3,227E-03 0,01899906 ! response to extracellular stimulus GO:0009991 72 72 3,000 3,252E-03 0,0190861 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 2,000 3,499E-03 0,02047011 ! positive regulation of cell migration GO:0030335 36 36 2,000 3,499E-03 0,02040533 ! embryonic limb morphogenesis GO:0030326 36 36 2,000 3,499E-03 0,02034096 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 2,000 3,499E-03 0,02027699 GO:0045937|positive regulation of phosphate metabolic process, ! integrin-mediated signaling pathway GO:0007229 36 36 2,000 3,499E-03 0,02021343 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 1,000 3,784E-03 0,02179218 ! protein amino acid acetylation GO:0006473 11 11 1,000 3,784E-03 0,0217243 ! regulation of transmembrane transporter activity GO:0022898 11 11 1,000 3,784E-03 0,02165683 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! spinal cord development GO:0021510 11 11 1,000 3,784E-03 0,02158978 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 3,784E-03 0,02152315 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 3,784E-03 0,02145692 ! G1/S transition checkpoint GO:0031575 12 11 1,000 3,784E-03 0,0213911 ! interaction with host GO:0051701 11 11 1,000 3,784E-03 0,02132569 ! oogenesis GO:0048477 11 11 1,000 3,784E-03 0,02126067 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 3,784E-03 0,02119605 GO:0006109|regulation of carbohydrate metabolic process, ! proximal/distal pattern formation GO:0009954 11 11 1,000 3,784E-03 0,02113182 ! meiosis GO:0007126 37 37 2,000 3,784E-03 0,02107133 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of growth GO:0045926 37 37 2,000 3,784E-03 0,02100786 ! chromosome segregation GO:0007059 38 38 2,000 4,084E-03 0,02260261 ! meiotic cell cycle GO:0051321 38 38 2,000 4,084E-03 0,02253493 ! steroid hormone receptor signaling pathway GO:0030518 38 38 2,000 4,084E-03 0,02246767 ! regulation of homeostatic process GO:0032844 38 38 2,000 4,084E-03 0,0224008 ! cell morphogenesis involved in differentiation GO:0000904 82 77 3,000 4,144E-03 0,022662 ! regulation of MAPKKK cascade GO:0043408 41 39 2,000 4,398E-03 0,02397819 ! developmental maturation GO:0021700 39 39 2,000 4,398E-03 0,02390745 ! limb development GO:0060173 39 39 2,000 4,398E-03 0,02383714 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 4,516E-03 0,02440531 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 1,000 4,516E-03 0,02433395 ! heterophilic cell adhesion GO:0007157 12 12 1,000 4,516E-03 0,02426301 ! hindlimb morphogenesis GO:0035137 12 12 1,000 4,516E-03 0,02419247 ! xenobiotic metabolic process GO:0006805 12 12 1,000 4,516E-03 0,02412235 ! actomyosin structure organization GO:0031032 12 12 1,000 4,516E-03 0,02405263 ! positive regulation of endocytosis GO:0045807 12 12 1,000 4,516E-03 0,02398332 ! male gonad development GO:0008584 12 12 1,000 4,516E-03 0,0239144 ! renal system process GO:0003014 12 12 1,000 4,516E-03 0,02384588 ! cell fate determination GO:0001709 12 12 1,000 4,516E-03 0,02377775 ! regulation of chromosome organization GO:0033044 12 12 1,000 4,516E-03 0,02371 ! somitogenesis GO:0001756 13 12 1,000 4,516E-03 0,02364265 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 4,516E-03 0,02357567 ! negative regulation of translation GO:0017148 12 12 1,000 4,516E-03 0,02350907 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 4,516E-03 0,02344285 ! regulation of locomotion GO:0040012 79 79 3,000 4,543E-03 0,02351794 ! DNA catabolic process GO:0006308 41 40 2,000 4,725E-03 0,02439451 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 2,000 4,725E-03 0,02432637 ! lymphocyte activation GO:0046649 82 81 3,000 4,967E-03 0,02549881 ! cell cycle checkpoint GO:0000075 42 41 2,000 5,068E-03 0,02594346 ! regulation of caspase activity GO:0043281 41 41 2,000 5,068E-03 0,0258716 ! positive regulation of DNA replication GO:0045740 14 13 1,000 5,307E-03 0,02702023 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 1,000 5,307E-03 0,02694579 ! regeneration GO:0031099 13 13 1,000 5,307E-03 0,02687177 ! post-embryonic development GO:0009791 14 13 1,000 5,307E-03 0,02679814 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 5,307E-03 0,02672493 ! response to corticosteroid stimulus GO:0031960 13 13 1,000 5,307E-03 0,02665211 GO:0051384|response to glucocorticoid stimulus, ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 5,307E-03 0,02657968 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 5,307E-03 0,02650765 ! negative regulation of intracellular transport GO:0032387 13 13 1,000 5,307E-03 0,02643601 ! response to cytokine stimulus GO:0034097 13 13 1,000 5,307E-03 0,02636475 ! camera-type eye morphogenesis GO:0048593 13 13 1,000 5,307E-03 0,02629388 ! blastocyst development GO:0001824 13 13 1,000 5,307E-03 0,02622339 ! regulation of endopeptidase activity GO:0052548 42 42 2,000 5,425E-03 0,02673094 ! protein ubiquitination GO:0016567 43 42 2,000 5,425E-03 0,02665966 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 2,000 5,425E-03 0,02658875 ! reproductive structure development GO:0048608 43 43 2,000 5,796E-03 0,02833508 ! homeostasis of number of cells GO:0048872 44 43 2,000 5,796E-03 0,02826012 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 3,000 6,142E-03 0,02986749 ! neuron fate commitment GO:0048663 14 14 1,000 6,158E-03 0,02986554 ! protein amino acid deacetylation GO:0006476 14 14 1,000 6,158E-03 0,02978715 ! negative regulation of epithelial cell proliferation GO:0050680 14 14 1,000 6,158E-03 0,02970918 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 1,000 6,158E-03 0,02963161 ! multicellular organismal response to stress GO:0033555 14 14 1,000 6,158E-03 0,02955444 ! base-excision repair GO:0006284 14 14 1,000 6,158E-03 0,02947768 ! response to organic cyclic substance GO:0014070 15 14 1,000 6,158E-03 0,02940131 ! DNA modification GO:0006304 14 14 1,000 6,158E-03 0,02932534 ! regulation of blood coagulation GO:0030193 15 14 1,000 6,158E-03 0,02924976 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 2,000 6,183E-03 0,02929257 ! protein import into nucleus GO:0006606 44 44 2,000 6,183E-03 0,02921746 ! phosphoinositide-mediated signaling GO:0048015 45 45 2,000 6,584E-03 0,03103608 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 2,000 6,584E-03 0,03095691 ! nuclear import GO:0051170 45 45 2,000 6,584E-03 0,03087814 ! regulation of peptidase activity GO:0052547 46 46 2,000 7,001E-03 0,03274998 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 2,000 7,001E-03 0,03266707 ! positive regulation of ligase activity GO:0051351 47 46 2,000 7,001E-03 0,03258457 ! positive regulation of fibroblast proliferation GO:0048146 15 15 1,000 7,066E-03 0,03280367 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 7,066E-03 0,03272125 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 1,000 7,066E-03 0,03263924 ! ovarian follicle development GO:0001541 15 15 1,000 7,066E-03 0,03255764 ! chromosome condensation GO:0030261 15 15 1,000 7,066E-03 0,03247645 ! protein homooligomerization GO:0051260 15 15 1,000 7,066E-03 0,03239567 ! negative regulation of cell cycle GO:0045786 92 91 3,000 7,49E-03 0,03425101 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 2,000 7,881E-03 0,03595429 ! protein localization in nucleus GO:0034504 48 48 2,000 7,881E-03 0,03586552 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 1,000 8,031E-03 0,03645788 ! positive regulation of mitosis GO:0045840 16 16 1,000 8,031E-03 0,0363683 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 8,031E-03 0,03627916 ! cellular response to reactive oxygen species GO:0034614 16 16 1,000 8,031E-03 0,03619046 ! segmentation GO:0035282 17 16 1,000 8,031E-03 0,03610219 ! positive regulation of cell development GO:0010720 16 16 1,000 8,031E-03 0,03601435 ! lymphocyte proliferation GO:0046651 16 16 1,000 8,031E-03 0,03592694 ! cell fate specification GO:0001708 16 16 1,000 8,031E-03 0,03583995 ! regulation of coagulation GO:0050818 17 16 1,000 8,031E-03 0,03575338 ! cell cycle arrest GO:0007050 49 49 2,000 8,345E-03 0,03705946 ! skeletal muscle tissue development GO:0007519 50 49 2,000 8,345E-03 0,03697037 GO:0060538|skeletal muscle organ development, ! regulation of ligase activity GO:0051340 50 49 2,000 8,345E-03 0,03688171 ! pattern specification process GO:0007389 96 94 3,000 8,385E-03 0,03696983 ! regulation of neurogenesis GO:0050767 51 50 2,000 8,824E-03 0,03881351 ! anatomical structure homeostasis GO:0060249 51 50 2,000 8,824E-03 0,0387211 ! regulation of cell growth GO:0001558 97 96 3,000 9,019E-03 0,0394837 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 9,052E-03 0,03953453 ! myelination GO:0042552 17 17 1,000 9,052E-03 0,03944107 ! regulation of transmembrane transport GO:0034762 17 17 1,000 9,052E-03 0,03934805 ! leukocyte adhesion GO:0007159 17 17 1,000 9,052E-03 0,03925546 ! dicarboxylic acid metabolic process GO:0043648 18 17 1,000 9,052E-03 0,03916331 ! glucose transport GO:0015758 17 17 1,000 9,052E-03 0,0390716 ! development of primary male sexual characteristics GO:0046546 17 17 1,000 9,052E-03 0,03898031 ! negative regulation of cell development GO:0010721 18 17 1,000 9,052E-03 0,03888945 GO:0050768|negative regulation of neurogenesis, ! regulation of osteoblast differentiation GO:0045667 17 17 1,000 9,052E-03 0,038799 ! pigmentation GO:0043473 17 17 1,000 9,052E-03 0,03870898 ! embryonic organ development GO:0048568 17 17 1,000 9,052E-03 0,03861938 ! gene silencing GO:0016458 17 17 1,000 9,052E-03 0,03853019 ! protein modification by small protein conjugation GO:0032446 52 51 2,000 9,319E-03 0,03957444 ! posttranscriptional regulation of gene expression GO:0010608 98 98 3,000 9,684E-03 0,04103084 ! anti-apoptosis GO:0006916 100 99 3,000 0,01002867 0,04239181 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 0,01012819 0,04271452 ! icosanoid biosynthetic process GO:0046456 18 18 1,000 0,01012819 0,042617 ! meiosis I GO:0007127 18 18 1,000 0,01012819 0,04251992 ! mononuclear cell proliferation GO:0032943 18 18 1,000 0,01012819 0,04242328 GO:0070661|leukocyte proliferation, ! hexose transport GO:0008645 18 18 1,000 0,01012819 0,04232709 GO:0015749|monosaccharide transport, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 0,01012819 0,04223132 ! telencephalon development GO:0021537 19 18 1,000 0,01012819 0,04213599 ! ensheathment of neurons GO:0007272 18 18 1,000 0,01012819 0,04204109 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 1,000 0,01012819 0,04194662 ! negative regulation of catabolic process GO:0009895 18 18 1,000 0,01012819 0,04185257 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 0,01012819 0,04175894 ! regulation of T cell activation GO:0050863 53 53 2,000 0,01035743 0,0426088 ! protein amino acid dephosphorylation GO:0006470 55 54 2,000 0,01090076 0,0447441 ! response to virus GO:0009615 54 54 2,000 0,01090076 0,04464467 ! negative regulation of multicellular organismal process GO:0051241 55 54 2,000 0,01090076 0,04454568 ! DNA damage checkpoint GO:0000077 19 19 1,000 0,01125779 0,04590289 ! glial cell differentiation GO:0010001 19 19 1,000 0,01125779 0,04580156 ! regulation of pH GO:0006885 19 19 1,000 0,01125779 0,04570068 ! regulation of JAK-STAT cascade GO:0046425 19 19 1,000 0,01125779 0,04560024 ! regulation of striated muscle tissue development GO:0016202 20 19 1,000 0,01125779 0,04550024 ! multicellular organismal metabolic process GO:0044236 19 19 1,000 0,01125779 0,04540067 ! cellular response to oxidative stress GO:0034599 19 19 1,000 0,01125779 0,04530155 ! peripheral nervous system development GO:0007422 19 19 1,000 0,01125779 0,04520285 ! eye morphogenesis GO:0048592 19 19 1,000 0,01125779 0,04510458 ! response to heat GO:0009408 19 19 1,000 0,01125779 0,04500674 ! in utero embryonic development GO:0001701 55 55 2,000 0,01146036 0,04571741 ! protein modification by small protein conjugation or removal GO:0070647 56 55 2,000 0,01146036 0,04561867 ! regulation of nervous system development GO:0051960 57 56 2,000 0,01203631 0,04780802 ! regulation of muscle development GO:0048634 21 20 1,000 0,01244025 0,04930618 ! establishment or maintenance of cell polarity GO:0007163 21 20 1,000 0,01244025 0,04920037 ! neural tube development GO:0021915 21 20 1,000 0,01244025 0,04909502 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 0,01244025 0,04899011 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 1,000 0,01244025 0,04888566 ! protein targeting to membrane GO:0006612 22 20 1,000 0,01244025 0,04878165 ! chromatin remodeling GO:0006338 20 20 1,000 0,01244025 0,04867808 ! female gamete generation GO:0007292 20 20 1,000 0,01244025 0,04857494 ! negative regulation of neuron apoptosis GO:0043524 21 20 1,000 0,01244025 0,04847225 ! regulation of B cell activation GO:0050864 20 20 1,000 0,01244025 0,04836999 ! regulation of binding GO:0051098 60 57 2,000 0,01262869 0,04899933 ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 0,01367459 0,05294596 ! protein amino acid lipidation GO:0006497 21 21 1,000 0,01367459 0,05283496 ! regulation of action potential in neuron GO:0019228 21 21 1,000 0,01367459 0,05272443 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 1,000 0,01367459 0,05261436 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 0,01367459 0,05250474 ! negative regulation of protein transport GO:0051224 21 21 1,000 0,01367459 0,05239559 ! dephosphorylation GO:0016311 60 59 2,000 0,01386303 0,05300739 ! regulation of cell development GO:0060284 60 59 2,000 0,01386303 0,05289764 ! protein localization in organelle GO:0033365 59 59 2,000 0,01386303 0,05278835 ! immune effector process GO:0002252 59 59 2,000 0,01386303 0,05267951 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 0,01495989 0,05673061 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 0,01495989 0,05661412 ! sister chromatid segregation GO:0000819 22 22 1,000 0,01495989 0,0564981 ! cellular amide metabolic process GO:0043603 22 22 1,000 0,01495989 0,05638257 ! odontogenesis GO:0042476 22 22 1,000 0,01495989 0,0562675 ! ovulation cycle process GO:0022602 22 22 1,000 0,01495989 0,0561529 ! spindle organization GO:0007051 22 22 1,000 0,01495989 0,05603877 ! male sex differentiation GO:0046661 22 22 1,000 0,01495989 0,0559251 ! biopolymer methylation GO:0043414 22 22 1,000 0,01495989 0,05581189 GO:0032259|methylation, ! neuron migration GO:0001764 22 22 1,000 0,01495989 0,05569914 ! proteasomal protein catabolic process GO:0010498 62 61 2,000 0,01516388 0,05634483 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! axonogenesis GO:0007409 66 62 2,000 0,01583939 0,05873641 ! protein import GO:0017038 62 62 2,000 0,01583939 0,05861846 ! regulation of lymphocyte activation GO:0051249 62 62 2,000 0,01583939 0,05850099 ! response to hydrogen peroxide GO:0042542 24 23 1,000 0,0162952 0,06006409 ! epithelial cell differentiation GO:0030855 23 23 1,000 0,0162952 0,0599442 ! response to estrogen stimulus GO:0043627 23 23 1,000 0,0162952 0,05982479 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 0,0162952 0,05970586 ! induction of apoptosis by extracellular signals GO:0008624 23 23 1,000 0,0162952 0,05958739 ! lipoprotein biosynthetic process GO:0042158 23 23 1,000 0,0162952 0,0594694 ! female gonad development GO:0008585 23 23 1,000 0,0162952 0,05935187 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 0,0162952 0,05923481 ! cell projection assembly GO:0030031 25 23 1,000 0,0162952 0,0591182 ! regulation of response to external stimulus GO:0032101 65 64 2,000 0,0172408 0,06242591 ! regulation of action potential GO:0001508 24 24 1,000 0,0176796 0,0638892 ! ovulation cycle GO:0042698 24 24 1,000 0,0176796 0,06376418 ! glucan metabolic process GO:0044042 25 24 1,000 0,0176796 0,06363964 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! negative regulation of protein metabolic process GO:0051248 66 66 2,000 0,01870964 0,06721612 ! development of primary female sexual characteristics GO:0046545 25 25 1,000 0,01911218 0,06852868 GO:0046660|female sex differentiation, ! positive regulation of DNA binding GO:0043388 26 25 1,000 0,01911218 0,06839561 ! heart morphogenesis GO:0003007 25 25 1,000 0,01911218 0,06826306 ! icosanoid metabolic process GO:0006690 25 25 1,000 0,01911218 0,06813102 ! regulation of endocytosis GO:0030100 25 25 1,000 0,01911218 0,0679995 ! JAK-STAT cascade GO:0007259 26 25 1,000 0,01911218 0,06786848 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 2,000 0,01946943 0,06900415 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! striated muscle tissue development GO:0014706 69 67 2,000 0,01946943 0,06887171 ! regulation of cell size GO:0008361 68 68 2,000 0,02024616 0,07148212 ! positive regulation of binding GO:0051099 27 26 1,000 0,02059204 0,07256429 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,02059204 0,07242581 ! double-strand break repair GO:0006302 27 26 1,000 0,02059204 0,07228786 ! germ cell development GO:0007281 27 26 1,000 0,02059204 0,07215043 ! pigment metabolic process GO:0042440 26 26 1,000 0,02059204 0,07201352 ! synapse organization GO:0050808 26 26 1,000 0,02059204 0,07187713 ! regulation of leukocyte activation GO:0002694 69 69 2,000 0,02103984 0,07330139 ! cell part morphogenesis GO:0032990 75 70 2,000 0,0218505 0,07598203 ! muscle tissue development GO:0060537 72 70 2,000 0,0218505 0,07583894 ! energy reserve metabolic process GO:0006112 28 27 1,000 0,0221183 0,0766241 ! activation of caspase activity GO:0006919 27 27 1,000 0,0221183 0,07648034 ! regulation of cell activation GO:0050865 71 71 2,000 0,02267814 0,07826932 ! sensory organ development GO:0007423 72 72 2,000 0,02352277 0,08103263 ! carbohydrate transport GO:0008643 28 28 1,000 0,02369007 0,08145672 ! unsaturated fatty acid metabolic process GO:0033559 28 28 1,000 0,02369007 0,08130503 ! viral reproductive process GO:0022415 29 29 1,000 0,0253065 0,08669124 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,02696674 0,09220723 GO:0043280|positive regulation of caspase activity, ! response to temperature stimulus GO:0009266 30 30 1,000 0,02696674 0,09203647 ! regulation of inflammatory response GO:0050727 30 30 1,000 0,02696674 0,09186635 ! vesicle organization GO:0016050 30 30 1,000 0,02696674 0,09169685 ! establishment of organelle localization GO:0051656 31 30 1,000 0,02696674 0,09152798 ! positive regulation of multicellular organismal process GO:0051240 76 76 2,000 0,02707107 0,0917132 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,02866993 0,0969517 ! lipoprotein metabolic process GO:0042157 31 31 1,000 0,02866993 0,09677413 ! camera-type eye development GO:0043010 31 31 1,000 0,02866993 0,09659721 ! regulation of myeloid cell differentiation GO:0045637 32 31 1,000 0,02866993 0,09642094 ! nuclear transport GO:0051169 79 79 2,000 0,02991029 0,10040922 GO:0006913|nucleocytoplasmic transport, ! muscle fiber development GO:0048747 32 32 1,000 0,03041524 0,10191871 ! regulation of vesicle-mediated transport GO:0060627 33 32 1,000 0,03041524 0,10173374 ! cell maturation GO:0048469 32 32 1,000 0,03041524 0,10154944 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,03041524 0,10136581 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,03041524 0,10118284 ! neuron projection development GO:0031175 85 80 2,000 0,03089049 0,1025787 ! activation of protein kinase activity GO:0032147 35 33 1,000 0,03220186 0,10674107 ! regulation of neuron differentiation GO:0045664 34 33 1,000 0,03220186 0,10654943 ! response to metal ion GO:0010038 34 34 1,000 0,03402898 0,1123932 ! ear development GO:0043583 34 34 1,000 0,03402898 0,11219214 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 0,03402898 0,1119918 ! secondary metabolic process GO:0019748 34 34 1,000 0,03402898 0,11179217 ! viral reproduction GO:0016032 34 34 1,000 0,03402898 0,11159325 ! multicellular organism reproduction GO:0032504 36 35 1,000 0,03589579 0,1175061 GO:0048609|reproductive process in a multicellular organism, ! inorganic anion transport GO:0015698 35 35 1,000 0,03589579 0,11729775 ! response to steroid hormone stimulus GO:0048545 35 35 1,000 0,03589579 0,11709015 ! response to inorganic substance GO:0010035 36 36 1,000 0,0378015 0,12308862 ! regulation of mitosis GO:0007088 37 36 1,000 0,0378015 0,12287153 GO:0051783|regulation of nuclear division, ! female pregnancy GO:0007565 37 36 1,000 0,0378015 0,12265521 ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,0378015 0,12243965 ! gonad development GO:0008406 36 36 1,000 0,0378015 0,12222484 ! coagulation GO:0050817 39 36 1,000 0,0378015 0,12201079 GO:0007596|blood coagulation, ! male gamete generation GO:0048232 90 88 2,000 0,03933577 0,12674094 GO:0007283|spermatogenesis, ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,03974533 0,12783708 GO:0090046|regulation of transcription regulator activity, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 0,03974533 0,12761437 ! eye development GO:0001654 37 37 1,000 0,03974533 0,12739243 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,03974533 0,12717126 ! negative regulation of kinase activity GO:0033673 38 38 1,000 0,04172652 0,133279 ! axon guidance GO:0007411 39 38 1,000 0,04172652 0,13304841 ! rRNA transcription GO:0009303 5 5 0,000 0,04216083 0,13420105 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,04216083 0,13396967 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,04216083 0,13373908 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,04216083 0,13350929 ! reproductive cellular process GO:0048610 5 5 0,000 0,04216083 0,13328029 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,04216083 0,13305207 ! water transport GO:0006833 5 5 0,000 0,04216083 0,13282463 GO:0042044|fluid transport, ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,04216083 0,13259796 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,04216083 0,13237207 ! glycerol metabolic process GO:0006071 5 5 0,000 0,04216083 0,13214695 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,04216083 0,13192259 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,04216083 0,13169899 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,04216083 0,13147615 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,04216083 0,13125406 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,04216083 0,13103273 ! filopodium assembly GO:0046847 7 5 0,000 0,04216083 0,13081213 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,04216083 0,13059228 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,04216083 0,13037316 ! GTP metabolic process GO:0046039 5 5 0,000 0,04216083 0,13015478 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,04216083 0,12993713 ! mRNA stabilization GO:0048255 5 5 0,000 0,04216083 0,12972021 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,04216083 0,12950401 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,04216083 0,12928853 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,04216083 0,12907376 ! social behavior GO:0035176 5 5 0,000 0,04216083 0,12885971 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,04216083 0,12864637 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,04216083 0,12843373 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,04216083 0,12822179 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,04216083 0,12801055 ! response to lipid GO:0033993 5 5 0,000 0,04216083 0,12780001 ! erythrocyte maturation GO:0043249 5 5 0,000 0,04216083 0,12759016 ! hippocampus development GO:0021766 6 5 0,000 0,04216083 0,12738099 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,04216083 0,12717251 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,04216083 0,12696472 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,04216083 0,1267576 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,04216083 0,12655115 ! mechanosensory behavior GO:0007638 5 5 0,000 0,04216083 0,12634538 ! heart looping GO:0001947 5 5 0,000 0,04216083 0,12614027 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,04216083 0,12593583 ! response to interferon-gamma GO:0034341 5 5 0,000 0,04216083 0,12573205 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,04216083 0,12552893 ! endocrine pancreas development GO:0031018 5 5 0,000 0,04216083 0,12532646 ! pH reduction GO:0045851 5 5 0,000 0,04216083 0,12512465 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,04216083 0,12492348 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,04216083 0,12472296 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,04216083 0,12452309 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,04216083 0,12432385 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,04216083 0,12412525 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,04216083 0,12392728 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,04216083 0,12372995 ! adrenal gland development GO:0030325 5 5 0,000 0,04216083 0,12353324 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,04216083 0,12333715 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,04216083 0,12314169 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,04216083 0,12294685 ! astrocyte differentiation GO:0048708 5 5 0,000 0,04216083 0,12275262 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,04216083 0,122559 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,04216083 0,12236599 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,04216083 0,12217359 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,04216083 0,1219818 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,04216083 0,12179061 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,04216083 0,12160001 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,04216083 0,12141001 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,04216083 0,1212206 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,04216083 0,12103179 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,04216083 0,12084356 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,04216083 0,12065591 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,04216083 0,12046885 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,04216083 0,12028236 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,04216083 0,12009645 ! response to ATP GO:0033198 5 5 0,000 0,04216083 0,11991112 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,04216083 0,11972636 ! regulation of appetite GO:0032098 5 5 0,000 0,04216083 0,11954216 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,04216083 0,11935854 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,04216083 0,11917547 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,04216083 0,11899297 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,04216083 0,11881102 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,04216083 0,11862963 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,04216083 0,11844879 ! receptor clustering GO:0043113 5 5 0,000 0,04216083 0,1182685 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,04216083 0,11808876 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,04216083 0,11790957 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,04216083 0,11773092 ! retinol metabolic process GO:0042572 5 5 0,000 0,04216083 0,11755281 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,04216083 0,11737524 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,04216083 0,1171982 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,04216083 0,1170217 ! parturition GO:0007567 5 5 0,000 0,04216083 0,11684572 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,04216083 0,11667028 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,04216083 0,11649536 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,04216083 0,11632097 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,04216083 0,11614709 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,04216083 0,11597374 ! oligodendrocyte development GO:0014003 5 5 0,000 0,04216083 0,1158009 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,04216083 0,11562858 ! activated T cell proliferation GO:0050798 5 5 0,000 0,04216083 0,11545677 ! interaction with symbiont GO:0051702 5 5 0,000 0,04216083 0,11528547 ! cellular extravasation GO:0045123 5 5 0,000 0,04216083 0,11511468 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,04216083 0,11494439 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,04216083 0,1147746 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,04216083 0,11460532 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,04216083 0,11443653 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,04216083 0,11426824 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,04216083 0,11410045 ! response to amine stimulus GO:0014075 5 5 0,000 0,04216083 0,11393315 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,04216083 0,11376633 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,04216083 0,11360001 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,04216083 0,11343417 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,04216083 0,11326881 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,04216083 0,11310394 ! neuron recognition GO:0008038 5 5 0,000 0,04216083 0,11293954 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,04216083 0,11277563 ! decidualization GO:0046697 5 5 0,000 0,04216083 0,11261218 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,04216083 0,11244921 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,04216083 0,11228671 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,04216083 0,11212468 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,04216083 0,11196312 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,04216083 0,11180202 ! postreplication repair GO:0006301 5 5 0,000 0,04216083 0,11164139 ! histone methylation GO:0016571 5 5 0,000 0,04216083 0,11148121 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,04216083 0,1113215 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,04216083 0,11116224 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,04216083 0,11100344 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,04216083 0,11084509 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,04216083 0,11068719 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,04216083 0,11052974 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,04216083 0,11037274 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,04216083 0,11021618 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,04216083 0,11006007 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,04216083 0,10990439 ! sterol catabolic process GO:0016127 5 5 0,000 0,04216083 0,10974916 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,04216083 0,10959437 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,04216083 0,10944001 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,04216083 0,10928608 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,04216083 0,10913259 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! zymogen activation GO:0031638 5 5 0,000 0,04216083 0,10897953 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,04216083 0,1088269 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,04216083 0,10867469 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,04216083 0,10852291 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,04216083 0,10837156 ! nucleosome positioning GO:0016584 5 5 0,000 0,04216083 0,10822062 ! regulation of isotype switching GO:0045191 5 5 0,000 0,04216083 0,10807011 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,04216083 0,10792001 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,04216083 0,10777033 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,04216083 0,10762106 ! NADPH regeneration GO:0006740 5 5 0,000 0,04216083 0,10747221 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,04216083 0,10732377 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,04216083 0,10717573 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,04216083 0,10702811 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,04216083 0,10688089 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,04216083 0,10673407 ! sarcomere organization GO:0045214 5 5 0,000 0,04216083 0,10658766 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,04216083 0,10644165 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,04216083 0,10629604 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,04216083 0,10615083 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,04216083 0,10600601 GO:0045622|regulation of T-helper cell differentiation, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,04216083 0,10586159 ! male genitalia development GO:0030539 5 5 0,000 0,04216083 0,10571756 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,04216083 0,10557392 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,04216083 0,10543067 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,04216083 0,10528781 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,04216083 0,10514534 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,04216083 0,10500325 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,04216083 0,10486155 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,04216083 0,10472022 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,04216083 0,10457928 ! ATP catabolic process GO:0006200 5 5 0,000 0,04216083 0,10443872 ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,04216083 0,10429853 ! blastocyst formation GO:0001825 5 5 0,000 0,04216083 0,10415872 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,04216083 0,10401929 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,04216083 0,10388022 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,04216083 0,10374153 ! activation of innate immune response GO:0002218 5 5 0,000 0,04216083 0,10360321 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,04216083 0,10346525 ! catecholamine transport GO:0051937 5 5 0,000 0,04216083 0,10332767 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,04216083 0,10319045 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,04216083 0,10305359 ! muscle adaptation GO:0043500 5 5 0,000 0,04216083 0,10291709 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,04216083 0,10278096 ! embryonic heart tube development GO:0035050 5 5 0,000 0,04216083 0,10264519 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,04216083 0,10250977 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,04216083 0,10237471 ! defense response to fungus GO:0050832 5 5 0,000 0,04216083 0,10224001 ! lysogeny GO:0030069 5 5 0,000 0,04216083 0,10210566 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,04216083 0,10197166 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,04216083 0,10183802 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,04216083 0,10170472 ! establishment of cell polarity GO:0030010 5 5 0,000 0,04216083 0,10157177 ! mitochondrion localization GO:0051646 5 5 0,000 0,04216083 0,10143917 ! nucleus localization GO:0051647 5 5 0,000 0,04216083 0,10130692 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,04216083 0,10117501 ! hemostasis GO:0007599 42 39 1,000 0,04374431 0,10483844 ! fatty acid biosynthetic process GO:0006633 39 39 1,000 0,04374431 0,10470228 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,04374431 0,10456648 ! fatty acid metabolic process GO:0006631 93 92 2,000 0,04395609 0,10493661 ! negative regulation of transferase activity GO:0051348 40 40 1,000 0,04579794 0,10919223 ! organelle localization GO:0051640 41 40 1,000 0,04579794 0,10905116 ! development of primary sexual characteristics GO:0045137 42 42 1,000 0,05000978 0,11892648 ! negative regulation of ligase activity GO:0051352 43 42 1,000 0,05000978 0,11877322 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 1,000 0,05000978 0,11862036 ! one-carbon metabolic process GO:0006730 42 42 1,000 0,05000978 0,11846789 ! axon extension GO:0048675 7 6 0,000 0,05038083 0,11919367 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,05038083 0,11904086 ! tRNA modification GO:0006400 6 6 0,000 0,05038083 0,11888844 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,05038083 0,11873641 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,05038083 0,11858476 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,05038083 0,11843351 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,05038083 0,11828264 ! regulation of S phase GO:0033261 6 6 0,000 0,05038083 0,11813215 ! myotube differentiation GO:0014902 6 6 0,000 0,05038083 0,11798204 ! bone remodeling GO:0046849 6 6 0,000 0,05038083 0,11783232 ! N-glycan processing GO:0006491 6 6 0,000 0,05038083 0,11768298 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,05038083 0,11753401 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,05038083 0,11738542 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,05038083 0,11723721 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,05038083 0,11708937 ! RNA methylation GO:0001510 6 6 0,000 0,05038083 0,1169419 ! cartilage condensation GO:0001502 7 6 0,000 0,05038083 0,1167948 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,05038083 0,11664808 GO:0050927|positive regulation of positive chemotaxis, ! artery development GO:0060840 6 6 0,000 0,05038083 0,11650172 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,05038083 0,11635573 ! bile acid metabolic process GO:0008206 6 6 0,000 0,05038083 0,1162101 ! androgen metabolic process GO:0008209 6 6 0,000 0,05038083 0,11606484 ! estrogen metabolic process GO:0008210 6 6 0,000 0,05038083 0,11591994 ! limbic system development GO:0021761 7 6 0,000 0,05038083 0,1157754 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,05038083 0,11563122 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,05038083 0,1154874 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,05038083 0,11534394 ! pathogenesis GO:0009405 6 6 0,000 0,05038083 0,11520083 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,05038083 0,11505808 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,05038083 0,11491568 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,05038083 0,11477363 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,05038083 0,11463194 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,05038083 0,11449059 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,05038083 0,11434959 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,05038083 0,11420894 ! arginine metabolic process GO:0006525 6 6 0,000 0,05038083 0,11406864 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,05038083 0,11392867 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,05038083 0,11378906 ! glutamate catabolic process GO:0006538 7 6 0,000 0,05038083 0,11364978 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,05038083 0,11351084 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,05038083 0,11337225 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,05038083 0,11323399 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,05038083 0,11309606 ! V(D)J recombination GO:0033151 6 6 0,000 0,05038083 0,11295848 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,05038083 0,11282123 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,05038083 0,11268431 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,05038083 0,11254772 ! regulation of heart rate GO:0002027 6 6 0,000 0,05038083 0,11241146 ! lipid digestion GO:0044241 6 6 0,000 0,05038083 0,11227554 ! asymmetric protein localization GO:0008105 6 6 0,000 0,05038083 0,11213994 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,05038083 0,11200467 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,05038083 0,11186972 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,05038083 0,1117351 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,05038083 0,1116008 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,05038083 0,11146683 ! ruffle organization GO:0031529 6 6 0,000 0,05038083 0,11133318 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,05038083 0,11119984 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,05038083 0,11106683 ! neutral amino acid transport GO:0015804 6 6 0,000 0,05038083 0,11093413 ! L-amino acid transport GO:0015807 6 6 0,000 0,05038083 0,11080175 ! bone mineralization GO:0030282 6 6 0,000 0,05038083 0,11066969 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,05038083 0,11053794 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,05038083 0,1104065 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,05038083 0,11027538 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,05038083 0,11014457 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,05038083 0,11001406 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,05038083 0,10988387 ! regulation of organ growth GO:0046620 6 6 0,000 0,05038083 0,10975398 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,05038083 0,1096244 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,05038083 0,10949513 ! response to dsRNA GO:0043331 6 6 0,000 0,05038083 0,10936616 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,05038083 0,10923749 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,05038083 0,10910913 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,05038083 0,10898107 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,05038083 0,10885331 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,05038083 0,10872584 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,05038083 0,10859868 ! multicellular organismal aging GO:0010259 6 6 0,000 0,05038083 0,10847181 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,05038083 0,10834524 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,05038083 0,10821896 ! erythrocyte development GO:0048821 6 6 0,000 0,05038083 0,10809298 ! renal water homeostasis GO:0003091 6 6 0,000 0,05038083 0,10796729 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,05038083 0,10784189 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,05038083 0,10771679 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,05038083 0,10759197 ! ribosome assembly GO:0042255 6 6 0,000 0,05038083 0,10746744 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,05038083 0,1073432 ! diencephalon development GO:0021536 6 6 0,000 0,05038083 0,10721925 ! fucose catabolic process GO:0019317 6 6 0,000 0,05038083 0,10709558 GO:0042355|L-fucose catabolic process, ! protein sumoylation GO:0016925 6 6 0,000 0,05038083 0,1069722 ! regulation of lipid transport GO:0032368 6 6 0,000 0,05038083 0,1068491 ! regulation of cell division GO:0051302 6 6 0,000 0,05038083 0,10672629 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,05038083 0,10660375 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,05038083 0,1064815 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,05038083 0,10635953 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,05038083 0,10623784 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,05038083 0,10611642 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,05038083 0,10599528 ! regulation of glucose transport GO:0010827 6 6 0,000 0,05038083 0,10587442 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,05038083 0,10575384 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,05038083 0,10563353 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,05038083 0,10551349 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,05038083 0,10539372 ! lymph node development GO:0048535 6 6 0,000 0,05038083 0,10527423 ! organic cation transport GO:0015695 6 6 0,000 0,05038083 0,105155 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,05038083 0,10503605 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,05038083 0,10491737 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,05038083 0,10479895 ! sperm-egg recognition GO:0035036 7 6 0,000 0,05038083 0,1046808 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,05038083 0,10456292 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,05038083 0,1044453 ! alditol metabolic process GO:0019400 6 6 0,000 0,05038083 0,10432794 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,05038083 0,10421085 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,05038083 0,10409402 ! maternal placenta development GO:0001893 6 6 0,000 0,05038083 0,10397746 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,05038083 0,10386115 ! localization within membrane GO:0051668 6 6 0,000 0,05038083 0,10374511 ! blood circulation GO:0008015 99 98 2,000 0,05137307 0,10567027 GO:0003013|circulatory system process, ! muscle organ development GO:0007517 102 100 2,000 0,05397284 0,11089403 ! response to other organism GO:0051707 101 100 2,000 0,05397284 0,11077054 ! humoral immune response GO:0006959 44 44 1,000 0,05435624 0,11143332 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,05435624 0,11130951 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,05657819 0,11573096 ! regulation of DNA binding GO:0051101 47 45 1,000 0,05657819 0,11560266 ! respiratory burst GO:0045730 7 7 0,000 0,05853147 0,11946125 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,05853147 0,1193291 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,05853147 0,11919725 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,05853147 0,11906568 ! regulation of chemokine production GO:0032642 7 7 0,000 0,05853147 0,11893441 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,05853147 0,11880342 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,05853147 0,11867273 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,05853147 0,11854232 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,05853147 0,11841219 GO:0043241|protein complex disassembly, ! gene silencing by RNA GO:0031047 7 7 0,000 0,05853147 0,11828235 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,05853147 0,1181528 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,05853147 0,11802353 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,05853147 0,11789454 ! axis specification GO:0009798 7 7 0,000 0,05853147 0,11776584 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,05853147 0,11763741 ! visual behavior GO:0007632 7 7 0,000 0,05853147 0,11750927 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,05853147 0,1173814 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,05853147 0,11725381 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,05853147 0,1171265 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,05853147 0,11699947 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,05853147 0,11687271 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,05853147 0,11674622 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,05853147 0,11662001 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,05853147 0,11649407 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,05853147 0,1163684 ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,05853147 0,116243 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,05853147 0,11611788 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,05853147 0,11599302 ! endoderm development GO:0007492 7 7 0,000 0,05853147 0,11586843 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,05853147 0,11574411 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,05853147 0,11562005 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,05853147 0,11549626 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,05853147 0,11537274 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,05853147 0,11524947 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,05853147 0,11512648 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,05853147 0,11500374 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,05853147 0,11488126 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,05853147 0,11475905 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,05853147 0,1146371 ! UV protection GO:0009650 7 7 0,000 0,05853147 0,1145154 ! DNA integration GO:0015074 7 7 0,000 0,05853147 0,11439396 ! myofibril assembly GO:0030239 7 7 0,000 0,05853147 0,11427278 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,05853147 0,11415186 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,05853147 0,11403119 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,05853147 0,11391078 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,05853147 0,11379062 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,05853147 0,11367071 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,05853147 0,11355106 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,05853147 0,11343166 GO:0019827|stem cell maintenance, ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,05853147 0,11331251 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,05853147 0,11319361 ! axon cargo transport GO:0008088 7 7 0,000 0,05853147 0,11307496 ! eating behavior GO:0042755 7 7 0,000 0,05853147 0,11295655 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,05853147 0,1128384 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,05853147 0,11272049 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,05853147 0,11260283 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,05853147 0,11248541 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,05853147 0,11236824 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,05853147 0,11225131 ! induction of an organ GO:0001759 7 7 0,000 0,05853147 0,11213462 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,05853147 0,11201818 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,05853147 0,11190198 ! intracellular lipid transport GO:0032365 7 7 0,000 0,05853147 0,11178602 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,05853147 0,1116703 ! platelet activation GO:0030168 8 7 0,000 0,05853147 0,11155482 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,05853147 0,11143957 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,05853147 0,11132457 ! natural killer cell activation GO:0030101 7 7 0,000 0,05853147 0,1112098 ! NADP metabolic process GO:0006739 7 7 0,000 0,05853147 0,11109527 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,05853147 0,11098097 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,05853147 0,11086691 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,05853147 0,11075309 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,05853147 0,11063949 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,05853147 0,11052613 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,05853147 0,11041301 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,05853147 0,11030011 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,05853147 0,11018744 ! cell-cell recognition GO:0009988 8 7 0,000 0,05853147 0,11007501 ! hormone catabolic process GO:0042447 7 7 0,000 0,05853147 0,1099628 ! dopamine metabolic process GO:0042417 7 7 0,000 0,05853147 0,10985082 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,05853147 0,10973907 ! oxygen transport GO:0015671 7 7 0,000 0,05853147 0,10962755 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,05853147 0,10951625 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,05853147 0,10940518 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,05853147 0,10929433 ! regulation of axon extension GO:0030516 7 7 0,000 0,05853147 0,10918371 ! cell killing GO:0001906 7 7 0,000 0,05853147 0,10907331 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,05853147 0,10896314 ! adult feeding behavior GO:0008343 7 7 0,000 0,05853147 0,10885319 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,05853147 0,10874345 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,05853147 0,10863394 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,05853147 0,10852466 ! response to cold GO:0009409 7 7 0,000 0,05853147 0,10841559 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 1,000 0,06111604 0,11308921 ! regulation of blood pressure GO:0008217 48 47 1,000 0,06111604 0,11297578 ! sex differentiation GO:0007548 47 47 1,000 0,06111604 0,11286258 ! rhythmic process GO:0048511 47 47 1,000 0,06111604 0,1127496 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,06343058 0,11690256 ! response to nutrient GO:0007584 49 49 1,000 0,06577465 0,12110159 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,06661334 0,12252333 ! positive regulation of translation GO:0045727 8 8 0,000 0,06661334 0,12240118 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,06661334 0,12227926 ! superoxide anion generation GO:0042554 8 8 0,000 0,06661334 0,12215759 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,06661334 0,12203616 ! cGMP metabolic process GO:0046068 8 8 0,000 0,06661334 0,12191498 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,06661334 0,12179403 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,06661334 0,12167332 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,06661334 0,12155285 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,06661334 0,12143262 ! zinc ion transport GO:0006829 8 8 0,000 0,06661334 0,12131263 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,06661334 0,12119287 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,06661334 0,12107335 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,06661334 0,12095407 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,06661334 0,12083502 ! lipid localization GO:0010876 8 8 0,000 0,06661334 0,1207162 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,06661334 0,12059762 ! response to cAMP GO:0051591 8 8 0,000 0,06661334 0,12047927 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,06661334 0,12036116 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,06661334 0,12024327 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,06661334 0,12012562 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,06661334 0,12000819 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,06661334 0,119891 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,06661334 0,11977403 ! sensory perception of taste GO:0050909 8 8 0,000 0,06661334 0,11965729 ! organelle fusion GO:0048284 8 8 0,000 0,06661334 0,11954078 ! pancreas development GO:0031016 8 8 0,000 0,06661334 0,11942449 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,06661334 0,11930844 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,06661334 0,1191926 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,06661334 0,11907699 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,06661334 0,11896161 ! sperm motility GO:0030317 8 8 0,000 0,06661334 0,11884645 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,06661334 0,11873151 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,06661334 0,11861679 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,06661334 0,1185023 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,06661334 0,11838802 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,06661334 0,11827397 GO:0031114|regulation of microtubule depolymerization, ! polyamine metabolic process GO:0006595 8 8 0,000 0,06661334 0,11816014 ! Golgi organization GO:0007030 8 8 0,000 0,06661334 0,11804652 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,06661334 0,11793312 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,06661334 0,11781994 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,06661334 0,11770698 ! fructose metabolic process GO:0006000 8 8 0,000 0,06661334 0,11759423 ! mannose metabolic process GO:0006013 9 8 0,000 0,06661334 0,1174817 ! NAD metabolic process GO:0019674 8 8 0,000 0,06661334 0,11736939 ! plasma membrane fusion GO:0045026 8 8 0,000 0,06661334 0,11725729 ! response to fungus GO:0009620 8 8 0,000 0,06661334 0,1171454 ! stem cell differentiation GO:0048863 8 8 0,000 0,06661334 0,11703373 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,06661334 0,11692227 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,06661334 0,11681102 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,06661334 0,11669998 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,06661334 0,11658916 ! regulation of vasodilation GO:0042312 8 8 0,000 0,06661334 0,11647854 ! vasoconstriction GO:0042310 8 8 0,000 0,06661334 0,11636813 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,06661334 0,11625794 ! muscle cell development GO:0055001 8 8 0,000 0,06661334 0,11614795 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,06661334 0,11603817 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,06661334 0,11592859 ! sensory perception of pain GO:0019233 8 8 0,000 0,06661334 0,11581923 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,06661334 0,11571007 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,06661334 0,11560111 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,06661334 0,11549236 ! tissue regeneration GO:0042246 8 8 0,000 0,06661334 0,11538382 ! salivary gland development GO:0007431 8 8 0,000 0,06661334 0,11527547 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,06661334 0,11516734 ! water homeostasis GO:0030104 8 8 0,000 0,06661334 0,1150594 ! cofactor transport GO:0051181 8 8 0,000 0,06661334 0,11495167 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,06661334 0,11484414 ! acid secretion GO:0046717 8 8 0,000 0,06661334 0,1147368 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,06661334 0,11462967 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,06661334 0,11452274 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,06661334 0,11441601 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,06661334 0,11430948 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,06661334 0,11420314 ! regulation of RNA stability GO:0043487 8 8 0,000 0,06661334 0,11409701 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,06661334 0,11399107 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,06661334 0,11388533 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,06661334 0,11377978 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,06661334 0,11367443 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,06661334 0,11356927 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,06661334 0,11346431 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,06661334 0,11335954 ! developmental induction GO:0031128 8 8 0,000 0,06661334 0,11325496 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,06661334 0,11315058 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,06661334 0,11304639 ! actin filament polymerization GO:0030041 9 8 0,000 0,06661334 0,11294239 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,06661334 0,11283858 ! peptide hormone processing GO:0016486 8 8 0,000 0,06661334 0,11273497 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,06661334 0,11263154 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,06661334 0,1125283 ! regulation of defense response GO:0031347 50 50 1,000 0,06814759 0,11501466 ! negative regulation of transport GO:0051051 51 50 1,000 0,06814759 0,11490944 ! regulation of body fluid levels GO:0050878 55 52 1,000 0,07297749 0,12294106 ! lactation GO:0007595 10 9 0,000 0,07462699 0,12560506 ! embryonic pattern specification GO:0009880 10 9 0,000 0,07462699 0,12549046 ! positive regulation of cell size GO:0045793 9 9 0,000 0,07462699 0,12537606 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,07462699 0,12526188 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,07462699 0,1251479 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,07462699 0,12503413 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,07462699 0,12492056 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,07462699 0,12480721 ! viral genome replication GO:0019079 9 9 0,000 0,07462699 0,12469405 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,07462699 0,12458111 ! copper ion transport GO:0006825 9 9 0,000 0,07462699 0,12446836 ! lipid phosphorylation GO:0046834 9 9 0,000 0,07462699 0,12435582 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,07462699 0,12424349 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,07462699 0,12413135 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,07462699 0,12401942 ! RNA polyadenylation GO:0043631 9 9 0,000 0,07462699 0,12390769 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,07462699 0,12379617 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,07462699 0,12368484 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,07462699 0,12357371 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,07462699 0,12346278 ! phospholipid efflux GO:0033700 9 9 0,000 0,07462699 0,12335205 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,07462699 0,12324152 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,07462699 0,12313119 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,07462699 0,12302106 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,07462699 0,12291112 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,07462699 0,12280138 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,07462699 0,12269183 ! methionine metabolic process GO:0006555 9 9 0,000 0,07462699 0,12258248 ! glutamine metabolic process GO:0006541 9 9 0,000 0,07462699 0,12247332 ! cerebral cortex development GO:0021987 9 9 0,000 0,07462699 0,12236436 ! pigmentation during development GO:0048066 9 9 0,000 0,07462699 0,12225559 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,07462699 0,12214702 ! central nervous system neuron development GO:0021954 10 9 0,000 0,07462699 0,12203863 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,07462699 0,12193044 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,07462699 0,12182244 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,07462699 0,12171464 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,07462699 0,12160702 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,07462699 0,12149959 ! L-glutamate transport GO:0015813 9 9 0,000 0,07462699 0,12139236 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,07462699 0,12128531 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,07462699 0,12117845 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,07462699 0,12107178 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,07462699 0,12096529 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,07462699 0,120859 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,07462699 0,12075289 ! DNA replication initiation GO:0006270 9 9 0,000 0,07462699 0,12064697 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,07462699 0,12054123 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,07462699 0,12043567 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,07462699 0,12033031 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,07462699 0,12022512 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,07462699 0,12012012 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,07462699 0,12001531 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,07462699 0,11991067 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,07462699 0,11980622 ! collagen catabolic process GO:0030574 9 9 0,000 0,07462699 0,11970195 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,07462699 0,11959786 ! purine base metabolic process GO:0006144 9 9 0,000 0,07462699 0,11949395 ! gas transport GO:0015669 9 9 0,000 0,07462699 0,11939023 ! cholesterol efflux GO:0033344 9 9 0,000 0,07462699 0,11928668 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,07462699 0,11918331 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,07462699 0,11908012 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,07462699 0,11897711 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,07462699 0,11887428 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,07462699 0,11877162 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,07462699 0,11866915 ! actin filament-based movement GO:0030048 9 9 0,000 0,07462699 0,11856684 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,07462699 0,11846472 ! hormone metabolic process GO:0042445 55 54 1,000 0,07791519 0,12357806 ! sulfur metabolic process GO:0006790 55 54 1,000 0,07791519 0,1234718 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,08042292 0,1273363 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,08257299 0,13062835 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,08257299 0,13051632 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,08257299 0,13040448 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,08257299 0,13029283 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,08257299 0,13018138 ! neuron maturation GO:0042551 10 10 0,000 0,08257299 0,13007011 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,08257299 0,12995903 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,08257299 0,12984815 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,08257299 0,12973745 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,08257299 0,12962694 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,08257299 0,12951662 ! hormone secretion GO:0046879 10 10 0,000 0,08257299 0,12940649 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,08257299 0,12929654 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,08257299 0,12918678 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,08257299 0,12907721 ! cAMP metabolic process GO:0046058 10 10 0,000 0,08257299 0,12896782 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,08257299 0,12885862 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,08257299 0,1287496 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,08257299 0,12864077 ! glial cell development GO:0021782 10 10 0,000 0,08257299 0,12853212 ! phototransduction GO:0007602 11 10 0,000 0,08257299 0,12842365 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,08257299 0,12831537 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,08257299 0,12820727 ! fat cell differentiation GO:0045444 10 10 0,000 0,08257299 0,12809935 ! myoblast differentiation GO:0045445 10 10 0,000 0,08257299 0,12799161 ! centrosome cycle GO:0007098 10 10 0,000 0,08257299 0,12788406 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,08257299 0,12777668 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,08257299 0,12766949 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,08257299 0,12756247 ! glutamate metabolic process GO:0006536 11 10 0,000 0,08257299 0,12745564 ! plasma membrane organization GO:0007009 10 10 0,000 0,08257299 0,12734898 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,08257299 0,1272425 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,08257299 0,1271362 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,08257299 0,12703007 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,08257299 0,12692413 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,08257299 0,12681836 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,08257299 0,12671276 ! exocrine system development GO:0035272 10 10 0,000 0,08257299 0,12660735 ! embryo implantation GO:0007566 11 10 0,000 0,08257299 0,1265021 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,08257299 0,12639703 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,08257299 0,12629214 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,08257299 0,12618742 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,08257299 0,12608287 ! protein export from nucleus GO:0006611 10 10 0,000 0,08257299 0,1259785 ! negative regulation of immune response GO:0050777 10 10 0,000 0,08257299 0,1258743 ! cytolysis GO:0019835 10 10 0,000 0,08257299 0,12577027 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,08257299 0,12566642 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,08257299 0,12556273 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,08257299 0,12545922 ! mRNA splice site selection GO:0006376 11 10 0,000 0,08257299 0,12535587 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,08257299 0,1252527 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,08257299 0,1251497 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,08257299 0,12504686 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,08257299 0,12494419 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,08257299 0,1248417 ! regulation of epidermis development GO:0045682 10 10 0,000 0,08257299 0,12473937 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,08257299 0,12463721 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,08257299 0,12453521 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,08257299 0,12443338 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,08257299 0,12433172 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,08257299 0,12423023 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,08257299 0,1241289 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,08257299 0,12402773 ! extracellular structure organization GO:0043062 56 56 1,000 0,08295576 0,1245012 ! protein secretion GO:0009306 11 11 0,000 0,09045192 0,13564108 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,09045192 0,1355308 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,09045192 0,1354207 ! negative regulation of defense response GO:0031348 11 11 0,000 0,09045192 0,13531078 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,09045192 0,13520104 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,09045192 0,13509148 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,09045192 0,13498209 ! skin development GO:0043588 11 11 0,000 0,09045192 0,13487288 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,09045192 0,13476385 ! signal complex assembly GO:0007172 11 11 0,000 0,09045192 0,13465499 ! microtubule-based transport GO:0010970 11 11 0,000 0,09045192 0,13454631 ! endothelial cell migration GO:0043542 11 11 0,000 0,09045192 0,13443781 ! peroxisomal transport GO:0043574 11 11 0,000 0,09045192 0,13432948 ! protein amino acid methylation GO:0006479 11 11 0,000 0,09045192 0,13422132 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,09045192 0,13411334 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,09045192 0,13400553 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,09045192 0,1338979 ! T cell proliferation GO:0042098 11 11 0,000 0,09045192 0,13379044 ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,09045192 0,13368315 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,09045192 0,13357603 ! smooth muscle contraction GO:0006939 11 11 0,000 0,09045192 0,13346908 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,09045192 0,13336231 ! digestive system process GO:0022600 11 11 0,000 0,09045192 0,1332557 ! mitotic spindle organization GO:0007052 11 11 0,000 0,09045192 0,13314927 ! fucose metabolic process GO:0006004 11 11 0,000 0,09045192 0,133043 ! membrane budding GO:0006900 11 11 0,000 0,09045192 0,13293691 ! monoamine transport GO:0015844 11 11 0,000 0,09045192 0,13283098 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,09045192 0,13272522 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,09045192 0,13261964 ! body fluid secretion GO:0007589 11 11 0,000 0,09045192 0,13251421 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,09045192 0,13240896 ! intermediate filament-based process GO:0045103 11 11 0,000 0,09045192 0,13230387 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,09045192 0,13219896 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,09045192 0,1320942 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,09045192 0,13198961 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,09045192 0,13188519 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,09045192 0,13178093 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,09045192 0,13167684 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,09045192 0,13157291 ! vitamin transport GO:0051180 11 11 0,000 0,09045192 0,13146915 ! muscle maintenance GO:0046716 12 11 0,000 0,09045192 0,13136555 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,09045192 0,13126211 ! steroid catabolic process GO:0006706 11 11 0,000 0,09045192 0,13115884 ! endocrine process GO:0050886 11 11 0,000 0,09045192 0,13105573 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,09045192 0,13095277 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,09045192 0,13084999 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,09045192 0,13074736 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,09332636 0,13479662 ! translational initiation GO:0006413 12 12 0,000 0,09826431 0,14181764 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,09826431 0,14170667 ! initiation of viral infection GO:0019059 12 12 0,000 0,09826431 0,14159588 ! iron ion transport GO:0006826 13 12 0,000 0,09826431 0,14148525 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,09826431 0,1413748 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,09826431 0,14126453 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,09826431 0,14115442 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,09826431 0,14104449 ! collagen metabolic process GO:0032963 12 12 0,000 0,09826431 0,14093473 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,09826431 0,14082514 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,09826431 0,14071571 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,09826431 0,14060646 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,09826431 0,14049738 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,09826431 0,14038847 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,09826431 0,14027973 GO:0051297|centrosome organization, ! retinoid metabolic process GO:0001523 12 12 0,000 0,09826431 0,14017115 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,09826431 0,14006274 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,09826431 0,1399545 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,09826431 0,13984643 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,09826431 0,13973852 ! acute-phase response GO:0006953 12 12 0,000 0,09826431 0,13963078 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,09826431 0,13952321 ! vacuolar transport GO:0007034 12 12 0,000 0,09826431 0,1394158 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,09826431 0,13930856 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,09826431 0,13920148 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,09826431 0,13909457 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,09826431 0,13898782 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,09826431 0,13888123 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,09826431 0,13877481 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,09826431 0,13866855 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,09826431 0,13856245 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,09826431 0,13845652 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,09826431 0,13835074 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,09826431 0,13824513 ! pallium development GO:0021543 13 12 0,000 0,09826431 0,13813968 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,09826431 0,13803439 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,09826431 0,13792927 ! detection of light stimulus GO:0009583 13 12 0,000 0,09826431 0,1378243 ! synaptogenesis GO:0007416 12 12 0,000 0,09826431 0,13771949 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,09826431 0,13761484 ! hormone transport GO:0009914 12 12 0,000 0,09826431 0,13751035 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,09826431 0,13740601 ! heme biosynthetic process GO:0006783 12 12 0,000 0,09826431 0,13730184 ! spermatid differentiation GO:0048515 13 12 0,000 0,09826431 0,13719782 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,09826431 0,13709396 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,09826431 0,13699026 ! neural tube closure GO:0001843 13 12 0,000 0,09826431 0,13688672 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,09826431 0,13678333 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,09864716 0,13721261 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,10133947 0,14085116 ! angiogenesis GO:0001525 65 64 1,000 0,10405233 0,14451277 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,10601073 0,14712182 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,10601073 0,14701112 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,10601073 0,14690058 ! phenol metabolic process GO:0018958 13 13 0,000 0,10601073 0,14679021 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,10601073 0,14668001 ! gluconeogenesis GO:0006094 13 13 0,000 0,10601073 0,14656997 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,10601073 0,1464601 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,10601073 0,14635039 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,10601073 0,14624085 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,10601073 0,14613147 ! keratinization GO:0031424 13 13 0,000 0,10601073 0,14602225 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,10601073 0,1459132 ! patterning of blood vessels GO:0001569 13 13 0,000 0,10601073 0,14580431 ! vasculogenesis GO:0001570 13 13 0,000 0,10601073 0,14569558 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,10601073 0,14558702 ! regulation of innate immune response GO:0045088 13 13 0,000 0,10601073 0,14547861 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,10601073 0,14537037 ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,10601073 0,14526229 ! autophagy GO:0006914 13 13 0,000 0,10601073 0,14515437 ! receptor metabolic process GO:0043112 14 13 0,000 0,10601073 0,1450466 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,10601073 0,144939 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,10601073 0,14483156 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,10601073 0,14472428 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,10601073 0,14461715 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,10601073 0,14451019 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,10601073 0,14440338 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,10601073 0,14429673 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,10601073 0,14419024 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,10601073 0,14408391 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,10601073 0,14397773 ! vasodilation GO:0042311 14 13 0,000 0,10601073 0,14387171 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,10601073 0,14376584 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,10601073 0,14366013 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,10601073 0,14355457 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,10601073 0,14344917 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,10601073 0,14334393 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,10601073 0,14323884 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,10601073 0,1431339 ! immunoglobulin production GO:0002377 13 13 0,000 0,10601073 0,14302912 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,10601073 0,14292449 ! cell-cell junction organization GO:0045216 13 13 0,000 0,10601073 0,14282001 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,10601073 0,14271569 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,10601073 0,14261151 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,10601073 0,14250749 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,10601073 0,14240363 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,10601073 0,14229991 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,10601073 0,14219634 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,10601073 0,14209293 ! telomere organization GO:0032200 13 13 0,000 0,10601073 0,14198966 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,10601073 0,14188655 ! regulation of amine transport GO:0051952 13 13 0,000 0,10601073 0,14178358 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,10601073 0,14168077 ! anion transport GO:0006820 65 65 1,000 0,1067852 0,14261241 ! regulation of hormone levels GO:0010817 66 65 1,000 0,1067852 0,14250914 ! DNA packaging GO:0006323 66 66 1,000 0,10953756 0,14607651 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,10953756 0,14597088 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,11369172 0,15139728 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,11369172 0,15128797 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,11369172 0,15117882 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,11369172 0,15106982 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,11369172 0,15096098 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,11369172 0,1508523 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,11369172 0,15074377 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,11369172 0,1506354 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,11369172 0,15052719 ! vesicle docking GO:0048278 14 14 0,000 0,11369172 0,15041913 ! superoxide metabolic process GO:0006801 15 14 0,000 0,11369172 0,15031122 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,11369172 0,15020347 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,11369172 0,15009588 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,11369172 0,14998843 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,11369172 0,14988115 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,11369172 0,14977401 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,11369172 0,14966703 GO:0033189|response to vitamin A, ! lysosome organization GO:0007040 14 14 0,000 0,11369172 0,1495602 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,11369172 0,14945353 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,11369172 0,149347 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,11369172 0,14924063 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,11369172 0,14913441 ! primary neural tube formation GO:0014020 15 14 0,000 0,11369172 0,14902834 ! peptide cross-linking GO:0018149 14 14 0,000 0,11369172 0,14892242 ! regulation of behavior GO:0050795 14 14 0,000 0,11369172 0,14881665 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,11369172 0,14871103 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,11369172 0,14860556 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,11369172 0,14850024 ! formation of primary germ layer GO:0001704 14 14 0,000 0,11369172 0,14839507 GO:0001707|mesoderm formation, ! collagen fibril organization GO:0030199 14 14 0,000 0,11369172 0,14829005 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,11369172 0,14818518 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,11369172 0,14808045 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,11369172 0,14797588 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,11369172 0,14787145 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,11369172 0,14776717 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,11369172 0,14766303 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,11369172 0,14755904 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,11369172 0,1474552 ! regulation of translation GO:0006417 69 69 1,000 0,1179064 0,15281399 ! sensory perception of sound GO:0007605 71 69 1,000 0,1179064 0,1527066 GO:0050954|sensory perception of mechanical stimulus, ! carboxylic acid biosynthetic process GO:0046394 70 70 1,000 0,12073157 0,15625582 GO:0016053|organic acid biosynthetic process, ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,12130783 0,15689146 ! positive regulation of ossification GO:0045778 15 15 0,000 0,12130783 0,15678144 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,12130783 0,15667157 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,12130783 0,15656185 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,12130783 0,15645229 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,12130783 0,15634289 ! response to vitamin GO:0033273 15 15 0,000 0,12130783 0,15623363 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,12130783 0,15612453 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,12130783 0,15601558 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,12130783 0,15590678 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,12130783 0,15579814 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,12130783 0,15568964 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,12130783 0,1555813 ! heme metabolic process GO:0042168 15 15 0,000 0,12130783 0,15547311 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,12130783 0,15536506 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,12130783 0,15525717 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,12130783 0,15514943 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,12130783 0,15504184 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,12130783 0,15493439 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,12130783 0,1548271 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,12130783 0,15471995 ! phospholipid transport GO:0015914 15 15 0,000 0,12130783 0,15461295 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,12130783 0,1545061 ! glutathione metabolic process GO:0006749 16 15 0,000 0,12130783 0,1543994 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,12130783 0,15429284 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,12130783 0,15418643 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,12130783 0,15408017 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,12130783 0,15397405 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,12130783 0,15386808 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,12130783 0,15376226 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,12130783 0,15365658 ! calcium ion homeostasis GO:0055074 71 71 1,000 0,1235737 0,15641918 GO:0006874|cellular calcium ion homeostasis, ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,1235737 0,15631182 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,1264323 0,15981805 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,12885959 0,16277466 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,12885959 0,16266317 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,12885959 0,16255183 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,12885959 0,16244064 ! learning GO:0007612 16 16 0,000 0,12885959 0,16232961 ! circadian rhythm GO:0007623 16 16 0,000 0,12885959 0,16221873 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,12885959 0,162108 ! vacuole organization GO:0007033 16 16 0,000 0,12885959 0,16199742 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,12885959 0,161887 ! vesicle targeting GO:0006903 17 16 0,000 0,12885959 0,16177672 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,12885959 0,16166659 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,12885959 0,16155661 ! iron ion homeostasis GO:0055072 16 16 0,000 0,12885959 0,16144679 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,12885959 0,16133711 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,12885959 0,16122758 ! pentose metabolic process GO:0019321 16 16 0,000 0,12885959 0,1611182 ! fatty acid transport GO:0015908 16 16 0,000 0,12885959 0,16100896 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,12885959 0,16089988 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,12885959 0,16079094 ! cofactor catabolic process GO:0051187 16 16 0,000 0,12885959 0,16068215 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,12885959 0,16057351 ! polyol metabolic process GO:0019751 16 16 0,000 0,12885959 0,16046501 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,12885959 0,16035667 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,12885959 0,16024846 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,12885959 0,16014041 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,12885959 0,16003249 GO:0001841|neural tube formation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,12885959 0,15992473 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,13634754 0,16910398 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,13634754 0,16899026 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,13634754 0,16887669 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,13634754 0,16876327 ! sensory perception of smell GO:0007608 17 17 0,000 0,13634754 0,16865001 ! tissue remodeling GO:0048771 17 17 0,000 0,13634754 0,1685369 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,13634754 0,16842394 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,13634754 0,16831113 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,13634754 0,16819847 ! neural crest cell development GO:0014032 19 17 0,000 0,13634754 0,16808596 GO:0014033|neural crest cell differentiation, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,13634754 0,1679736 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,13634754 0,1678614 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,13634754 0,16774934 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,13634754 0,16763743 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,13634754 0,16752568 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,13634754 0,16741407 ! adult locomotory behavior GO:0008344 17 17 0,000 0,13634754 0,16730261 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,13634754 0,16719129 ! liver development GO:0001889 17 17 0,000 0,13634754 0,16708013 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,13802192 0,16901953 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,14095582 0,17249773 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,14377221 0,17582759 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,14377221 0,17571099 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 0,000 0,14377221 0,17559455 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,14377221 0,17547826 ! membrane docking GO:0022406 18 18 0,000 0,14377221 0,17536213 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,14377221 0,17524615 ! response to calcium ion GO:0051592 18 18 0,000 0,14377221 0,17513032 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,14377221 0,17501465 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,14377221 0,17489913 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,14377221 0,17478376 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,14377221 0,17466854 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,14377221 0,17455348 ! ceramide metabolic process GO:0006672 18 18 0,000 0,14377221 0,17443856 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,14377221 0,1743238 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! hexose biosynthetic process GO:0019319 18 18 0,000 0,14377221 0,17420919 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,14377221 0,17409473 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,14377221 0,17398042 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,14377221 0,17386626 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,14390342 0,17391082 ! metal ion homeostasis GO:0055065 78 78 1,000 0,14390342 0,17379686 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,15113412 0,18241007 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,15113412 0,18229069 GO:0006956|complement activation, ! feeding behavior GO:0007631 19 19 0,000 0,15113412 0,18217147 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,15113412 0,1820524 ! peroxisome organization GO:0007031 19 19 0,000 0,15113412 0,18193349 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,15113412 0,18181474 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,15113412 0,18169614 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,15113412 0,18157769 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,15113412 0,1814594 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,15113412 0,18134126 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,15113412 0,18122328 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,15113412 0,18110545 ! regulation of cell shape GO:0008360 21 19 0,000 0,15113412 0,18098777 ! placenta development GO:0001890 19 19 0,000 0,15113412 0,18087025 ! vesicle localization GO:0051648 20 19 0,000 0,15113412 0,18075287 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,1584338 0,18936024 ! negative regulation of binding GO:0051100 21 20 0,000 0,1584338 0,18923751 ! organic ether metabolic process GO:0018904 20 20 0,000 0,1584338 0,18911495 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,1584338 0,18899255 ! phagocytosis GO:0006909 21 20 0,000 0,1584338 0,1888703 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,1584338 0,18874821 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,1584338 0,18862628 ! lipid oxidation GO:0034440 20 20 0,000 0,1584338 0,18850451 GO:0019395|fatty acid oxidation, ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,1584338 0,18838289 ! RNA modification GO:0009451 20 20 0,000 0,1584338 0,18826143 ! single fertilization GO:0007338 21 20 0,000 0,1584338 0,18814013 ! blood vessel morphogenesis GO:0048514 84 83 1,000 0,15883175 0,18849125 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,16185254 0,19195253 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,16488408 0,19542209 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 0,16488408 0,1952965 ! mRNA catabolic process GO:0006402 21 21 0,000 0,16567176 0,19610343 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,16567176 0,19597756 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,16567176 0,19585186 ! Notch signaling pathway GO:0007219 22 21 0,000 0,16567176 0,19572631 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,16567176 0,19560093 ! ear morphogenesis GO:0042471 21 21 0,000 0,16567176 0,1954757 ! organic anion transport GO:0015711 21 21 0,000 0,16567176 0,19535064 ! cholesterol transport GO:0030301 21 21 0,000 0,16567176 0,19522573 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,16567176 0,19510099 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,16567176 0,1949764 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,16567176 0,19485198 ! regulation of proteolysis GO:0030162 21 21 0,000 0,16567176 0,19472771 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,16567176 0,1946036 ! RNA export from nucleus GO:0006405 22 22 0,000 0,17284851 0,20290433 ! regulation of ion transport GO:0043269 22 22 0,000 0,17284851 0,20277518 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,17284851 0,20264619 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,17284851 0,20251736 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,17284851 0,20238869 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,17284851 0,20226019 ! cell chemotaxis GO:0060326 23 22 0,000 0,17284851 0,20213186 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,17284851 0,20200368 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,17284851 0,20187567 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,17284851 0,20174782 ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,17284851 0,20162013 ! detection of external stimulus GO:0009581 23 22 0,000 0,17284851 0,2014926 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,17284851 0,20136524 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,17284851 0,20123803 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,17284851 0,20111099 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,17284851 0,2009841 ! aerobic respiration GO:0009060 22 22 0,000 0,17284851 0,20085738 ! cytokine production GO:0001816 22 22 0,000 0,17284851 0,20073082 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,17284851 0,20060441 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,17710993 0,20542076 ! viral infectious cycle GO:0019058 23 23 0,000 0,17996457 0,20860044 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,17996457 0,20846933 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,17996457 0,20833838 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,17996457 0,2082076 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,17996457 0,20807698 ! endocrine system development GO:0035270 23 23 0,000 0,17996457 0,20794652 ! lipid homeostasis GO:0055088 23 23 0,000 0,17996457 0,20781623 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,17996457 0,2076861 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,17996457 0,20755614 ! DNA replication GO:0006260 91 91 1,000 0,18327733 0,2112446 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,18327733 0,21111257 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,18637336 0,21454472 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,18702044 0,21515522 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,18702044 0,215021 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,18702044 0,21488695 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,18702044 0,21475307 ! fertilization GO:0009566 25 24 0,000 0,18702044 0,21461935 ! maintenance of protein location GO:0045185 25 24 0,000 0,18702044 0,21448579 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,18702044 0,21435241 ! blood vessel development GO:0001568 95 94 1,000 0,19258828 0,22059676 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,19401662 0,2220948 ! negative regulation of secretion GO:0051048 26 25 0,000 0,19401662 0,22195694 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,19401662 0,22181925 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,19401662 0,22168173 ! endosome transport GO:0016197 25 25 0,000 0,19401662 0,22154438 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,19401662 0,2214072 ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,19401662 0,22127019 ! excretion GO:0007588 25 25 0,000 0,19401662 0,22113335 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,19401662 0,22099668 ! gastrulation GO:0007369 25 25 0,000 0,19401662 0,22086018 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,19401662 0,22072384 ! vasculature development GO:0001944 97 96 1,000 0,19883136 0,22606181 ! positive regulation of defense response GO:0031349 26 26 0,000 0,2009536 0,22833384 ! glycolysis GO:0006096 26 26 0,000 0,2009536 0,22819315 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,2009536 0,22805264 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,2009536 0,2279123 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,2009536 0,22777213 ! cellular defense response GO:0006968 26 26 0,000 0,2009536 0,22763214 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,2009536 0,22749231 ! regulation of protein secretion GO:0050708 26 26 0,000 0,2009536 0,22735266 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,2009536 0,22721318 GO:0035150|regulation of tube size, ! maintenance of location in cell GO:0051651 27 26 0,000 0,2009536 0,22707387 ! endocytosis GO:0006897 99 98 1,000 0,20509989 0,2316171 GO:0010324|membrane invagination, ! chloride transport GO:0006821 27 27 0,000 0,20783188 0,23455858 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,20783188 0,23441503 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,20783188 0,23427166 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,20783188 0,23412846 ! peptide metabolic process GO:0006518 29 27 0,000 0,20783188 0,23398543 ! inner ear development GO:0048839 27 27 0,000 0,20783188 0,23384259 ! defense response to bacterium GO:0042742 27 27 0,000 0,20783188 0,23369991 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,20783188 0,23355741 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,20783188 0,23341509 ! cell growth GO:0016049 27 27 0,000 0,20783188 0,23327293 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,21465195 0,24078122 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! neuromuscular process GO:0050905 28 28 0,000 0,21465195 0,24063476 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,21465195 0,24048847 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,21465195 0,24034237 ! cartilage development GO:0051216 29 28 0,000 0,21465195 0,24019644 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,22141429 0,24761318 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,22141429 0,24746302 ! leukocyte migration GO:0050900 30 29 0,000 0,22141429 0,24731305 ! antigen processing and presentation GO:0019882 29 29 0,000 0,22141429 0,24716325 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,22141429 0,24701364 ! tRNA processing GO:0008033 29 29 0,000 0,22141429 0,2468642 ! adult behavior GO:0030534 30 29 0,000 0,22141429 0,24671495 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,22141429 0,24656588 ! transition metal ion transport GO:0000041 31 30 0,000 0,22811937 0,25387923 ! RNA catabolic process GO:0006401 30 30 0,000 0,22811937 0,25372601 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,22811937 0,25357298 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,22811937 0,25342014 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,22811937 0,25326747 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,22811937 0,25311499 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,22811937 0,2529627 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,22811937 0,25281059 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,22811937 0,25265866 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,22811937 0,25250691 GO:0019724|B cell mediated immunity, ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,22811937 0,25235535 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,22811937 0,25220396 ! regulation of translational initiation GO:0006446 31 31 0,000 0,23476769 0,25939859 ! membrane fusion GO:0006944 31 31 0,000 0,23476769 0,25924317 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,23476769 0,25908793 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,23476769 0,25893288 ! ion transmembrane transport GO:0034220 31 31 0,000 0,23476769 0,25877802 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,23476769 0,25862334 ! digestion GO:0007586 31 31 0,000 0,23476769 0,25846885 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,23476769 0,25831454 ! regulation of heart contraction GO:0008016 31 31 0,000 0,23476769 0,25816041 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,23476769 0,25800647 ! extracellular matrix organization GO:0030198 31 31 0,000 0,23476769 0,25785271 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,23476769 0,25769914 ! cell redox homeostasis GO:0045454 32 32 0,000 0,2413597 0,26477734 ! glucose catabolic process GO:0006007 32 32 0,000 0,2413597 0,26461983 ! lipid modification GO:0030258 32 32 0,000 0,2413597 0,2644625 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,2413597 0,26430537 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,2413597 0,26414842 ! nuclear export GO:0051168 32 32 0,000 0,2413597 0,26399165 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,2413597 0,26383507 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,2413597 0,26367868 ! maintenance of location GO:0051235 33 32 0,000 0,2413597 0,26352247 ! amino acid transport GO:0006865 33 33 0,000 0,24789588 0,27049859 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,24789588 0,27033853 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,24789588 0,27017866 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,24789588 0,27001898 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,24789588 0,26985949 ! regulation of actin filament length GO:0030832 34 34 0,000 0,2543767 0,27675104 ! muscle cell differentiation GO:0042692 35 34 0,000 0,2543767 0,27658776 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,2543767 0,27642468 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,2543767 0,27626179 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,2543767 0,27609909 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,2543767 0,27593659 ! detection of stimulus GO:0051606 36 34 0,000 0,2543767 0,27577427 ! acute inflammatory response GO:0002526 35 35 0,000 0,26080261 0,28257449 ! regulation of cellular component size GO:0032535 35 35 0,000 0,26080261 0,28240847 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,26080261 0,28224264 ! mesoderm development GO:0007498 35 35 0,000 0,26080261 0,282077 ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,26080261 0,28191156 ! regulation of immune effector process GO:0002697 35 35 0,000 0,26080261 0,28174631 ! hydrogen transport GO:0006818 36 36 0,000 0,26717407 0,28846035 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,26717407 0,28829146 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,26717407 0,28812277 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,26717407 0,28795428 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,26717407 0,28778598 ! regulation of lipase activity GO:0060191 36 36 0,000 0,26717407 0,28761788 ! activation of immune response GO:0002253 36 36 0,000 0,26717407 0,28744998 ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,27349153 0,2940752 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,27349153 0,29390373 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,27349153 0,29373246 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,27349153 0,29356139 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,27349153 0,29339051 ! adaptive immune response GO:0002250 37 37 0,000 0,27349153 0,29321984 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,27975545 0,29976122 ! neurotransmitter transport GO:0006836 40 38 0,000 0,27975545 0,29958704 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,27975545 0,29941307 ! exocytosis GO:0006887 40 38 0,000 0,27975545 0,29923929 ! hexose catabolic process GO:0019320 38 38 0,000 0,27975545 0,29906572 ! RNA elongation GO:0006354 38 38 0,000 0,27975545 0,29889235 ! regulation of neurological system process GO:0031644 38 38 0,000 0,27975545 0,29871918 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,28596627 0,3051742 ! response to unfolded protein GO:0006986 39 39 0,000 0,28596627 0,30499759 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,28596627 0,30482119 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,28596627 0,304645 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,28596627 0,304469 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,28596627 0,30429321 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,29212444 0,31066667 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,29212444 0,31048751 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,29823038 0,31679458 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,29823038 0,31661209 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,29823038 0,31642982 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,29823038 0,31624775 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,29823038 0,31606589 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,29823038 0,31588425 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,29823038 0,31570281 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,30428454 0,32192676 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,30428454 0,32174206 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,30428454 0,32155757 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,31028735 0,32771323 ! alcohol catabolic process GO:0046164 43 43 0,000 0,31028735 0,32752554 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,31028735 0,32733806 ! mRNA transport GO:0051028 44 44 0,000 0,31623924 0,33342615 ! vitamin metabolic process GO:0006766 44 44 0,000 0,31623924 0,33323551 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,31623924 0,33304509 ! amine biosynthetic process GO:0009309 46 45 0,000 0,32214062 0,33906635 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,32214062 0,33887281 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,32214062 0,3386795 ! protein processing GO:0016485 45 45 0,000 0,32214062 0,33848641 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,32799193 0,34443825 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,32799193 0,3442421 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,32799193 0,34404618 ! amine transport GO:0015837 47 47 0,000 0,33379358 0,34993264 ! calcium ion transport GO:0006816 48 48 0,000 0,33954599 0,35576081 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,33954599 0,35555867 ! DNA recombination GO:0006310 48 48 0,000 0,33954599 0,35535676 ! ossification GO:0001503 50 49 0,000 0,34524956 0,36112085 GO:0060348|bone development, ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,34524956 0,36091602 ! divalent metal ion transport GO:0070838 49 49 0,000 0,34524956 0,36071142 ! response to bacterium GO:0009617 50 49 0,000 0,34524956 0,36050705 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,34524956 0,36030291 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,34524956 0,360099 GO:0002696|positive regulation of leukocyte activation, ! chromatin assembly GO:0031497 50 50 0,000 0,3509047 0,36579036 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,3509047 0,36558359 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,3509047 0,36537704 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,3509047 0,36517073 ! transcription initiation GO:0006352 50 50 0,000 0,3509047 0,36496465 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,35651182 0,3705873 ! positive regulation of immune response GO:0050778 51 51 0,000 0,35651182 0,3703784 ! rRNA metabolic process GO:0016072 51 51 0,000 0,35651182 0,37016974 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,35651182 0,36996131 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,35651182 0,36975311 ! protein maturation GO:0051604 51 51 0,000 0,35651182 0,36954515 ! RNA localization GO:0006403 52 52 0,000 0,36207132 0,37509693 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,36207132 0,3748862 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,36207132 0,37467571 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,36207132 0,37446545 ! sodium ion transport GO:0006814 53 53 0,000 0,36758359 0,3799532 ! tRNA metabolic process GO:0006399 53 53 0,000 0,36758359 0,37974022 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,36758359 0,37952748 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,36758359 0,37931498 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,36758359 0,37910272 ! nucleosome organization GO:0034728 55 55 0,000 0,37846803 0,39010995 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,37846803 0,38989188 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,38384098 0,39520611 ! ATP metabolic process GO:0046034 57 57 0,000 0,38916827 0,4004674 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,38916827 0,40024392 ! innate immune response GO:0045087 58 58 0,000 0,39445026 0,40544999 ! carboxylic acid transport GO:0046942 59 59 0,000 0,39968735 0,41060412 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,39968735 0,41037537 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,39968735 0,41014688 ! potassium ion transport GO:0006813 60 60 0,000 0,40487991 0,41524412 ! protein polymerization GO:0051258 65 60 0,000 0,40487991 0,41501317 ! cellular respiration GO:0045333 62 61 0,000 0,41002831 0,4200568 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,41002831 0,41982343 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,41513292 0,42481398 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,41513292 0,42457823 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,41513292 0,42434275 ! regulation of secretion GO:0051046 65 63 0,000 0,42019411 0,42927813 ! glucose metabolic process GO:0006006 63 63 0,000 0,42019411 0,4290403 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,42019411 0,42880273 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,42019411 0,42856543 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,42521223 0,43344366 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,42521223 0,43320406 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,43512073 0,44305387 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,43512073 0,44280923 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,44001182 0,44753962 ! muscle contraction GO:0006936 67 67 0,000 0,44001182 0,44729277 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,44001182 0,44704619 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,44486127 0,45172414 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,44486127 0,4514754 ! translational elongation GO:0006414 71 71 0,000 0,45916326 0,46573356 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,45916326 0,46547738 ! ribosome biogenesis GO:0042254 71 71 0,000 0,45916326 0,46522149 ! secretion by cell GO:0032940 75 72 0,000 0,46384961 0,46971145 ! muscle system process GO:0003012 72 72 0,000 0,46384961 0,4694535 ! regulation of cytokine production GO:0001817 72 72 0,000 0,46384961 0,46919585 ! electron transport chain GO:0022900 75 74 0,000 0,47310287 0,47829325 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,47310287 0,47803103 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,47767045 0,48238172 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,47767045 0,48211755 ! microtubule-based movement GO:0007018 82 78 0,000 0,4911409 0,49544208 ! regulation of immune response GO:0050776 78 78 0,000 0,4911409 0,49517105 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,49993087 0,50375757 ! lipid catabolic process GO:0016042 82 81 0,000 0,5042697 0,50785195 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,51283664 0,51619767 ! ncRNA processing GO:0034470 83 83 0,000 0,51283664 0,5159159 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,521258 0,52410174 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,52541485 0,52799322 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,52541485 0,52770549 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,53362238 0,53565689 ! chemotaxis GO:0006935 90 89 0,000 0,53767366 0,53942981 GO:0042330|taxis, ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,54169034 0,54316392 ! visual perception GO:0007601 93 92 0,000 0,54962105 0,55081653 GO:0050953|sensory perception of light stimulus, ! positive regulation of immune system process GO:0002684 92 92 0,000 0,54962105 0,55051717 ! cofactor metabolic process GO:0051186 95 94 0,000 0,55741681 0,55802237 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,57261248 0,57292335 ! regulation of system process GO:0044057 98 98 0,000 0,57261248 0,57261248