pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6473-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! induction of apoptosis by intracellular signals GO:0008629 93 45 8,000 1,803E-12 4,339E-09 ! interphase of mitotic cell cycle GO:0051329 209 95 7,000 3,965E-08 4,77E-05 ! interphase GO:0051325 213 98 7,000 5,065E-08 4,062E-05 ! negative regulation of protein kinase activity GO:0006469 130 67 6,000 6,391E-08 3,844E-05 ! negative regulation of kinase activity GO:0033673 131 68 6,000 7,093E-08 3,413E-05 ! negative regulation of transferase activity GO:0051348 140 72 6,000 1,059E-07 4,247E-05 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 4,000 1,82E-07 6,257E-05 ! insulin receptor signaling pathway GO:0008286 64 26 4,000 2,244E-07 6,749E-05 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 5,000 5,514E-07 1,474E-04 ! positive regulation of cell migration GO:0030335 126 57 5,000 5,514E-07 1,327E-04 ! release of cytochrome c from mitochondria GO:0001836 30 14 3,000 7,006E-07 1,532E-04 ! positive regulation of cell motion GO:0051272 146 64 5,000 1,105E-06 2,216E-04 ! cellular response to insulin stimulus GO:0032869 82 37 4,000 1,419E-06 2,627E-04 ! apoptotic mitochondrial changes GO:0008637 41 20 3,000 3,309E-06 5,687E-04 ! positive regulation of locomotion GO:0040017 39 21 3,000 4,071E-06 6,53E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! G1/S transition of mitotic cell cycle GO:0000082 115 46 4,000 4,297E-06 6,462E-04 ! response to insulin stimulus GO:0032868 95 46 4,000 4,297E-06 6,082E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 4,882E-06 6,526E-04 ! anaphase GO:0051322 17 7 2,000 4,882E-06 6,183E-04 GO:0000090|mitotic anaphase, ! regulation of chemotaxis GO:0050920 40 22 3,000 4,955E-06 5,961E-04 ! regulation of behavior GO:0050795 43 24 3,000 7,139E-06 8,18E-04 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 7,139E-06 7,808E-04 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 2,000 7,782E-06 8,14E-04 ! ER overload response GO:0006983 12 8 2,000 7,782E-06 7,801E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 7,782E-06 7,489E-04 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 3,000 8,465E-06 7,833E-04 ! response to endoplasmic reticulum stress GO:0034976 43 25 3,000 8,465E-06 7,543E-04 ! response to UV GO:0009411 104 53 4,000 8,734E-06 7,505E-04 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 9,963E-06 8,266E-04 GO:0045936|negative regulation of phosphate metabolic process, ! induction of positive chemotaxis GO:0050930 15 9 2,000 1,163E-05 9,325E-04 ! regulation of fibroblast proliferation GO:0048145 52 27 3,000 1,165E-05 9,04E-04 ! ER-nuclear signaling pathway GO:0006984 48 28 3,000 1,353E-05 1,018E-03 ! cell cycle arrest GO:0007050 213 100 5,000 1,504E-05 1,097E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 2,000 1,655E-05 1,171E-03 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 1,655E-05 1,137E-03 ! response to peptide hormone stimulus GO:0043434 122 61 4,000 1,75E-05 1,17E-03 ! chondrocyte differentiation GO:0002062 24 11 2,000 2,266E-05 1,474E-03 ! negative regulation of glucose import GO:0046325 17 11 2,000 2,266E-05 1,435E-03 GO:0010829|negative regulation of glucose transport, ! T cell receptor signaling pathway GO:0050852 23 11 2,000 2,266E-05 1,398E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 4,000 2,771E-05 1,667E-03 ! regulation of positive chemotaxis GO:0050926 19 12 2,000 3,01E-05 1,767E-03 GO:0050927|positive regulation of positive chemotaxis, ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 4,942E-05 2,831E-03 ! positive regulation of phosphorylation GO:0042327 129 79 4,000 6,147E-05 3,439E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 6,154E-05 3,365E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 4,000 6,929E-05 3,705E-03 GO:0045937|positive regulation of phosphate metabolic process, ! cellular response to hormone stimulus GO:0032870 167 82 4,000 7,348E-05 3,843E-03 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 3,000 7,673E-05 3,928E-03 ! positive regulation of response to external stimulus GO:0032103 77 43 3,000 7,673E-05 3,846E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 3,000 7,673E-05 3,768E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 2,000 9,127E-05 4,392E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 9,127E-05 4,306E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 9,127E-05 4,223E-03 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 2,000 9,127E-05 4,143E-03 ! positive regulation of cell cycle GO:0045787 89 48 3,000 1,185E-04 5,282E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 4,000 1,336E-04 5,846E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 1,512E-04 6,498E-03 ! regulation of glucose import GO:0046324 29 20 2,000 1,512E-04 6,384E-03 GO:0010827|regulation of glucose transport, ! regulation of DNA metabolic process GO:0051052 178 97 4,000 1,629E-04 6,759E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 1,758E-04 7,168E-03 ! positive regulation of inflammatory response GO:0050729 35 21 2,000 1,758E-04 7,049E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 2,028E-04 7,997E-03 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 2,000 2,028E-04 7,868E-03 ! cellular response to reactive oxygen species GO:0034614 31 22 2,000 2,028E-04 7,743E-03 ! regulation of DNA replication GO:0006275 101 56 3,000 2,166E-04 8,142E-03 ! positive regulation of DNA replication GO:0045740 43 23 2,000 2,323E-04 8,597E-03 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 2,000 2,323E-04 8,467E-03 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 2,644E-04 9,496E-03 ! protein tetramerization GO:0051262 52 24 2,000 2,644E-04 9,356E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 2,707E-04 9,438E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 2,707E-04 9,303E-03 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 2,707E-04 9,172E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 2,707E-04 9,045E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 2,707E-04 8,921E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 2,707E-04 8,8E-03 ! DNA damage response, signal transduction GO:0042770 128 60 3,000 2,829E-04 9,076E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 2,829E-04 8,956E-03 ! myelination GO:0042552 45 25 2,000 2,993E-04 9,353E-03 ! cellular response to oxidative stress GO:0034599 39 26 2,000 3,371E-04 0,0103975 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 3,778E-04 0,01150477 ! regulation of chromosome organization GO:0033044 42 27 2,000 3,778E-04 0,01136096 ! male meiosis GO:0007140 7 6 1,000 4,046E-04 0,01201832 ! activation of MAPKKK activity GO:0000185 12 6 1,000 4,046E-04 0,01187175 ! negative regulation of platelet activation GO:0010544 9 6 1,000 4,046E-04 0,01172872 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 1,000 4,046E-04 0,01158909 ! establishment of spindle localization GO:0051293 12 6 1,000 4,046E-04 0,01145275 GO:0051653|spindle localization, ! monocyte differentiation GO:0030224 12 6 1,000 4,046E-04 0,01131958 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 4,046E-04 0,01118947 ! actin filament organization GO:0007015 148 66 3,000 4,081E-04 0,01115681 ! negative regulation of protein modification process GO:0031400 60 28 2,000 4,215E-04 0,01139365 ! activation of immune response GO:0002253 105 67 3,000 4,322E-04 0,01155448 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 3,000 4,574E-04 0,01209252 ! immune response-activating signal transduction GO:0002757 47 29 2,000 4,683E-04 0,01224672 GO:0002764|immune response-regulating signal transduction, ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 4,683E-04 0,01211504 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 3,000 4,835E-04 0,01237664 ! cell junction assembly GO:0034329 78 30 2,000 5,183E-04 0,0131272 ! ensheathment of neurons GO:0007272 57 30 2,000 5,183E-04 0,01299046 GO:0008366|axon ensheathment, ! regulation of helicase activity GO:0051095 15 7 1,000 5,645E-04 0,01400184 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 5,645E-04 0,01385896 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 5,645E-04 0,01371897 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 5,645E-04 0,01358178 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 5,645E-04 0,01344731 ! B cell lineage commitment GO:0002326 21 7 1,000 5,645E-04 0,01331547 ! T cell lineage commitment GO:0002360 16 7 1,000 5,645E-04 0,0131862 ! response to tumor cell GO:0002347 13 7 1,000 5,645E-04 0,01305941 ! regulation of respiratory burst GO:0060263 11 7 1,000 5,645E-04 0,01293503 ! coenzyme A metabolic process GO:0015936 12 7 1,000 5,645E-04 0,012813 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 1,000 5,645E-04 0,01269326 ! regulation of caspase activity GO:0043281 122 72 3,000 5,685E-04 0,01266425 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 3,000 5,685E-04 0,01254806 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 3,000 5,685E-04 0,01243399 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 3,000 5,685E-04 0,01232197 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 6,284E-04 0,01349881 ! BMP signaling pathway GO:0030509 64 32 2,000 6,284E-04 0,01337935 ! regulation of endopeptidase activity GO:0052548 125 74 3,000 6,307E-04 0,0133101 ! leukocyte chemotaxis GO:0030595 50 33 2,000 6,886E-04 0,01440589 GO:0060326|cell chemotaxis, ! positive regulation of ligase activity GO:0051351 124 77 3,000 7,328E-04 0,01519832 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 7,501E-04 0,01542447 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 7,501E-04 0,01529376 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 7,501E-04 0,01516524 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 1,000 7,501E-04 0,01503886 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 7,501E-04 0,01491457 ! ATP catabolic process GO:0006200 11 8 1,000 7,501E-04 0,01479232 ! B cell receptor signaling pathway GO:0050853 16 8 1,000 7,501E-04 0,01467206 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 3,000 8,07E-04 0,0156581 ! regulation of peptidase activity GO:0052547 134 79 3,000 8,07E-04 0,01553283 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 3,000 8,07E-04 0,01540956 ! negative regulation of hydrolase activity GO:0051346 62 35 2,000 8,197E-04 0,01552867 ! cell junction organization GO:0034330 86 36 2,000 8,908E-04 0,01674362 ! negative regulation of cell activation GO:0050866 65 36 2,000 8,908E-04 0,01661383 ! keratinocyte proliferation GO:0043616 14 9 1,000 9,611E-04 0,01778683 ! microtubule bundle formation GO:0001578 21 9 1,000 9,611E-04 0,01765106 ! middle ear morphogenesis GO:0042474 14 9 1,000 9,611E-04 0,01751734 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 1,000 9,611E-04 0,01738563 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! motor axon guidance GO:0008045 16 9 1,000 9,611E-04 0,01725588 ! protein heterooligomerization GO:0051291 16 9 1,000 9,611E-04 0,01712806 ! regulation of developmental growth GO:0048638 15 9 1,000 9,611E-04 0,01700212 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 9,611E-04 0,01687802 ! Golgi to endosome transport GO:0006895 23 9 1,000 9,611E-04 0,01675571 ! regulation of glycolysis GO:0006110 21 9 1,000 9,611E-04 0,01663517 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 1,000 9,611E-04 0,01651635 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 9,611E-04 0,01639921 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 1,000 9,611E-04 0,01628372 ! regulation of telomere maintenance GO:0032204 14 9 1,000 9,611E-04 0,01616985 ! regulation of ligase activity GO:0051340 142 84 3,000 1,016E-03 0,01696795 ! positive regulation of DNA metabolic process GO:0051054 72 38 2,000 1,044E-03 0,01732993 ! mitochondrion organization GO:0007005 148 86 3,000 1,109E-03 0,01827005 ! regulation of action potential in neuron GO:0019228 73 39 2,000 1,127E-03 0,01844777 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 1,197E-03 0,01946221 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 1,000 1,197E-03 0,01933159 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,197E-03 0,01920272 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,197E-03 0,01907555 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 1,197E-03 0,01895005 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 1,000 1,197E-03 0,01882619 ! negative regulation of BMP signaling pathway GO:0030514 19 10 1,000 1,197E-03 0,01870394 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,197E-03 0,01858327 GO:0043470|regulation of carbohydrate catabolic process, ! localization within membrane GO:0051668 20 10 1,000 1,197E-03 0,01846415 ! positive regulation of protein modification process GO:0031401 136 88 3,000 1,208E-03 0,01850636 ! cytokinesis GO:0000910 72 40 2,000 1,214E-03 0,01848404 ! response to reactive oxygen species GO:0000302 67 42 2,000 1,4E-03 0,02117932 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,458E-03 0,02192737 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,458E-03 0,02179118 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 1,458E-03 0,02165667 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,458E-03 0,0215238 ! regulation of intracellular pH GO:0051453 19 11 1,000 1,458E-03 0,02139256 ! substrate-bound cell migration GO:0006929 13 11 1,000 1,458E-03 0,02126291 ! embryonic axis specification GO:0000578 18 11 1,000 1,458E-03 0,02113482 ! purine ribonucleotide catabolic process GO:0009154 17 11 1,000 1,458E-03 0,02100826 ! DNA methylation GO:0006306 19 11 1,000 1,458E-03 0,02088321 GO:0006305|DNA alkylation, ! regulation of embryonic development GO:0045995 27 11 1,000 1,458E-03 0,02075964 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 3,000 1,482E-03 0,02097108 GO:0010498|proteasomal protein catabolic process, ! positive regulation of immune response GO:0050778 156 96 3,000 1,666E-03 0,02343452 ! leukocyte migration GO:0050900 68 45 2,000 1,71E-03 0,02392378 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 1,744E-03 0,02425185 ! virus-host interaction GO:0019048 29 12 1,000 1,744E-03 0,02411247 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,744E-03 0,02397469 ! positive regulation of cell growth GO:0030307 22 12 1,000 1,744E-03 0,02383847 ! focal adhesion formation GO:0048041 35 12 1,000 1,744E-03 0,02370379 ! histone acetylation GO:0016573 26 12 1,000 1,744E-03 0,02357062 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,744E-03 0,02343894 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 1,744E-03 0,02330872 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 1,744E-03 0,02317995 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 1,823E-03 0,02409424 ! positive regulation of defense response GO:0031349 76 47 2,000 1,939E-03 0,02549859 ! negative regulation of lipid metabolic process GO:0045833 19 13 1,000 2,054E-03 0,02685515 ! endocrine pancreas development GO:0031018 22 13 1,000 2,054E-03 0,02670999 ! ribonucleotide catabolic process GO:0009261 20 13 1,000 2,054E-03 0,02656639 ! cell-cell junction assembly GO:0007043 27 13 1,000 2,054E-03 0,02642432 ! response to X-ray GO:0010165 25 13 1,000 2,054E-03 0,02628377 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 2,054E-03 0,0261447 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! nucleoside triphosphate catabolic process GO:0009143 21 13 1,000 2,054E-03 0,02600709 ! regulation of cellular pH GO:0030641 22 13 1,000 2,054E-03 0,02587093 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 2,054E-03 0,02573619 ! actin filament polymerization GO:0030041 24 13 1,000 2,054E-03 0,02560284 ! activation of caspase activity GO:0006919 84 48 2,000 2,061E-03 0,0255583 ! regulation of inflammatory response GO:0050727 75 48 2,000 2,061E-03 0,02542723 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 2,061E-03 0,0252975 ! regulation of action potential GO:0001508 95 49 2,000 2,187E-03 0,02670816 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 2,187E-03 0,02657327 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 2,388E-03 0,02886978 ! negative regulation of caspase activity GO:0043154 22 14 1,000 2,388E-03 0,02872544 ! response to gamma radiation GO:0010332 28 14 1,000 2,388E-03 0,02858252 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 2,453E-03 0,02921713 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of muscle contraction GO:0006937 81 52 2,000 2,593E-03 0,03073545 ! positive regulation of growth GO:0045927 90 52 2,000 2,593E-03 0,03058479 ! cartilage development GO:0051216 90 52 2,000 2,593E-03 0,03043559 ! positive regulation of cell size GO:0045793 27 15 1,000 2,746E-03 0,03206877 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 2,746E-03 0,03191385 ! G1/S transition checkpoint GO:0031575 40 15 1,000 2,746E-03 0,03176042 ! positive regulation of caspase activity GO:0043280 95 55 2,000 3,043E-03 0,03503475 GO:0010952|positive regulation of peptidase activity, ! regulation of glucose metabolic process GO:0010906 28 16 1,000 3,127E-03 0,03582843 ! activation of MAPKK activity GO:0000186 35 16 1,000 3,127E-03 0,03565863 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 3,127E-03 0,03549043 GO:0031114|regulation of microtubule depolymerization, ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 3,127E-03 0,03532381 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 3,127E-03 0,03515874 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 3,532E-03 0,03952506 ! signal complex assembly GO:0007172 41 17 1,000 3,532E-03 0,03934208 ! negative regulation of peptidase activity GO:0010466 27 17 1,000 3,532E-03 0,03916078 ! regulation of survival gene product expression GO:0045884 33 17 1,000 3,532E-03 0,03898114 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 3,532E-03 0,03880314 ! negative regulation of blood coagulation GO:0030195 24 17 1,000 3,532E-03 0,03862677 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 3,532E-03 0,03845198 ! regulation of heart contraction GO:0008016 110 60 2,000 3,895E-03 0,04220859 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 3,895E-03 0,04201931 ! regulation of lipid biosynthetic process GO:0046890 25 18 1,000 3,96E-03 0,04253265 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 3,96E-03 0,04234361 ! centrosome cycle GO:0007098 25 18 1,000 3,96E-03 0,04215625 ! cell-substrate junction assembly GO:0007044 54 18 1,000 3,96E-03 0,04197054 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 3,96E-03 0,04178646 ! regulation of BMP signaling pathway GO:0030510 32 18 1,000 3,96E-03 0,04160399 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 1,000 3,96E-03 0,0414231 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 3,96E-03 0,04124378 ! skin development GO:0043588 36 19 1,000 4,41E-03 0,04573984 ! lipid phosphorylation GO:0046834 35 19 1,000 4,41E-03 0,04554353 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 1,000 4,41E-03 0,0453489 ! cellular response to unfolded protein GO:0034620 33 19 1,000 4,41E-03 0,04515592 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 42 19 1,000 4,41E-03 0,04496459 ! neuromuscular junction development GO:0007528 34 19 1,000 4,41E-03 0,04477486 ! plasma membrane fusion GO:0045026 28 19 1,000 4,41E-03 0,04458673 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 4,41E-03 0,04440018 ! cell-cell junction organization GO:0045216 35 19 1,000 4,41E-03 0,04421518 ! purine nucleotide catabolic process GO:0006195 29 19 1,000 4,41E-03 0,04403171 ! protein amino acid acetylation GO:0006473 39 20 1,000 4,884E-03 0,04855487 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 4,884E-03 0,04835506 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 4,884E-03 0,04815688 GO:0010675|regulation of cellular carbohydrate metabolic process, ! response to alkaloid GO:0043279 38 20 1,000 4,884E-03 0,04796032 ! pancreas development GO:0031016 35 20 1,000 4,884E-03 0,04776536 ! cellular response to starvation GO:0009267 33 20 1,000 4,884E-03 0,04757198 ! actin polymerization or depolymerization GO:0008154 48 20 1,000 4,884E-03 0,04738016 ! peptidyl-serine modification GO:0018209 43 20 1,000 4,884E-03 0,04718988 ! negative regulation of T cell activation GO:0050868 40 20 1,000 4,884E-03 0,04700112 ! negative regulation of coagulation GO:0050819 29 20 1,000 4,884E-03 0,04681386 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 4,884E-03 0,04662809 ! negative regulation of cell growth GO:0030308 132 67 2,000 5,308E-03 0,05048298 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 2,000 5,308E-03 0,05028423 ! axis specification GO:0009798 38 21 1,000 5,379E-03 0,05075542 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 5,379E-03 0,05055716 ! cell aging GO:0007569 44 21 1,000 5,379E-03 0,05036044 ! DNA modification GO:0006304 34 21 1,000 5,379E-03 0,05016524 ! negative regulation of ligase activity GO:0051352 112 68 2,000 5,532E-03 0,0513934 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! negative regulation of cell size GO:0045792 134 69 2,000 5,762E-03 0,05331942 ! apoptotic nuclear changes GO:0030262 32 22 1,000 5,897E-03 0,05436059 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 5,897E-03 0,05415311 ! positive regulation of B cell activation GO:0050871 38 22 1,000 5,897E-03 0,0539472 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 5,897E-03 0,05374286 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 5,897E-03 0,05354005 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 6,436E-03 0,05821858 ! myeloid leukocyte differentiation GO:0002573 40 23 1,000 6,436E-03 0,05800053 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 6,436E-03 0,05778411 ! purine ribonucleoside metabolic process GO:0046128 34 23 1,000 6,436E-03 0,0575693 GO:0042278|purine nucleoside metabolic process, ! sex determination GO:0007530 47 23 1,000 6,436E-03 0,05735608 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 6,436E-03 0,05714443 ! platelet activation GO:0030168 37 23 1,000 6,436E-03 0,05693434 ! meiosis GO:0007126 121 74 2,000 6,994E-03 0,06164376 GO:0051327|M phase of meiotic cell cycle, ! protein import into nucleus, translocation GO:0000060 46 24 1,000 6,998E-03 0,06144575 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 6,998E-03 0,06122231 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 6,998E-03 0,06100049 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 1,000 6,998E-03 0,06078027 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 6,998E-03 0,06056164 ! cell-matrix adhesion GO:0007160 163 75 2,000 7,258E-03 0,06259294 ! meiotic cell cycle GO:0051321 122 75 2,000 7,258E-03 0,06236939 ! negative regulation of DNA replication GO:0008156 42 25 1,000 7,58E-03 0,06490221 ! response to starvation GO:0042594 42 25 1,000 7,58E-03 0,06467206 ! negative regulation of cell development GO:0010721 73 25 1,000 7,58E-03 0,06444354 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 7,58E-03 0,06421662 ! somitogenesis GO:0001756 43 25 1,000 7,58E-03 0,0639913 ! regulation of blood coagulation GO:0030193 40 25 1,000 7,58E-03 0,06376756 ! cellular response to nutrient levels GO:0031669 41 25 1,000 7,58E-03 0,06354537 ! negative regulation of organelle organization GO:0010639 161 78 2,000 8,085E-03 0,06754134 ! protein oligomerization GO:0051259 139 78 2,000 8,085E-03 0,06730764 ! embryonic pattern specification GO:0009880 44 26 1,000 8,184E-03 0,06789562 ! microtubule organizing center organization GO:0031023 39 26 1,000 8,184E-03 0,0676623 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 8,184E-03 0,06743058 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 8,184E-03 0,06720045 ! positive regulation of nuclear division GO:0051785 40 26 1,000 8,184E-03 0,06697187 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 1,000 8,184E-03 0,06674485 ! protein import into nucleus GO:0006606 158 80 2,000 8,665E-03 0,07043443 ! protein amino acid acylation GO:0043543 55 27 1,000 8,808E-03 0,0713542 ! fat cell differentiation GO:0045444 50 27 1,000 8,808E-03 0,07111476 ! mitochondrial membrane organization GO:0007006 57 27 1,000 8,808E-03 0,07087692 ! base-excision repair GO:0006284 41 27 1,000 8,808E-03 0,07064066 ! glutathione metabolic process GO:0006749 39 27 1,000 8,808E-03 0,07040598 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 8,808E-03 0,07017284 ! response to hypoxia GO:0001666 171 81 2,000 8,964E-03 0,07118296 ! cell-substrate adhesion GO:0031589 171 81 2,000 8,964E-03 0,07094881 ! nuclear import GO:0051170 161 81 2,000 8,964E-03 0,07071619 ! response to drug GO:0042493 143 82 2,000 9,27E-03 0,07288464 ! dendrite development GO:0016358 59 28 1,000 9,453E-03 0,07408588 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 9,453E-03 0,07384534 ! response to oxygen levels GO:0070482 176 83 2,000 9,581E-03 0,0746001 ! negative regulation of transport GO:0051051 153 84 2,000 9,898E-03 0,07682159 ! negative regulation of growth GO:0045926 155 84 2,000 9,898E-03 0,07657458 ! regulation of pH GO:0006885 43 29 1,000 0,01011873 0,07803101 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01011873 0,07778171 ! complement activation, classical pathway GO:0006958 48 29 1,000 0,01011873 0,07753399 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 0,01011873 0,07728785 ! regulation of coagulation GO:0050818 46 29 1,000 0,01011873 0,07704327 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 0,01080448 0,08200496 ! regulation of B cell activation GO:0050864 50 30 1,000 0,01080448 0,08174709 ! protein localization in nucleus GO:0034504 176 87 2,000 0,01088619 0,0821071 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 1,000 0,01151019 0,08654224 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01151019 0,08627264 ! spindle organization GO:0007051 46 32 1,000 0,01223564 0,09142534 ! response to ionizing radiation GO:0010212 65 32 1,000 0,01223564 0,09114229 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01223564 0,09086098 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01223564 0,09058141 ! positive regulation of catabolic process GO:0009896 64 32 1,000 0,01223564 0,09030356 ! regulation of defense response GO:0031347 149 92 2,000 0,01265574 0,09311841 ! DNA damage checkpoint GO:0000077 71 33 1,000 0,01298062 0,09521757 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,01298062 0,09492816 ! regulation of membrane potential GO:0042391 164 93 2,000 0,01302821 0,0949875 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,01374489 0,09990996 ! leukocyte differentiation GO:0002521 202 96 2,000 0,01418299 0,10278396 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,01452823 0,10496975 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01452823 0,10465547 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,01452823 0,10434307 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,01533044 0,10977688 ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,01533044 0,10945113 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,01539411 0,10958054 GO:0060538|skeletal muscle organ development, ! cellular component assembly involved in morphogenesis GO:0010927 59 37 1,000 0,01615128 0,11463122 ! meiosis I GO:0007127 65 37 1,000 0,01615128 0,11429407 ! sister chromatid segregation GO:0000819 58 37 1,000 0,01615128 0,1139589 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,01615128 0,11362568 ! glycogen metabolic process GO:0005977 61 37 1,000 0,01615128 0,11329441 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 1,000 0,01699055 0,11883509 GO:0006956|complement activation, ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,01699055 0,11849064 ! carbohydrate homeostasis GO:0033500 53 38 1,000 0,01699055 0,11814818 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 67 38 1,000 0,01699055 0,11780769 ! nucleotide catabolic process GO:0009166 61 38 1,000 0,01699055 0,11746916 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,01699055 0,11713258 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 1,000 0,01699055 0,11679791 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 0,01784804 0,12234295 ! learning GO:0007612 77 39 1,000 0,01784804 0,12199538 ! segmentation GO:0035282 67 39 1,000 0,01784804 0,12164979 ! ear morphogenesis GO:0042471 60 39 1,000 0,01784804 0,12130614 ! feeding behavior GO:0007631 59 40 1,000 0,01872352 0,126898 ! ribonucleoside metabolic process GO:0009119 55 40 1,000 0,01872352 0,12654155 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,0196168 0,13220731 ! T cell differentiation GO:0030217 81 41 1,000 0,0196168 0,13183802 ! keratinocyte differentiation GO:0030216 62 41 1,000 0,0196168 0,13147078 ! regulation of T cell differentiation GO:0045580 70 41 1,000 0,0196168 0,13110559 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02052765 0,13681312 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,02052765 0,13643518 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,02052765 0,13605933 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,02145589 0,14182107 ! glucose transport GO:0015758 65 43 1,000 0,02145589 0,14143252 ! hexose transport GO:0008645 67 44 1,000 0,02240129 0,14726097 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,02240129 0,14685971 ! double-strand break repair GO:0006302 81 44 1,000 0,02240129 0,14646064 ! biopolymer methylation GO:0043414 84 44 1,000 0,02240129 0,14606372 ! B cell differentiation GO:0030183 107 44 1,000 0,02240129 0,14566896 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,02336367 0,15151748 ! cell growth GO:0016049 84 45 1,000 0,02336367 0,15111017 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,02434281 0,1570209 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,02434281 0,15660106 ! epidermal cell differentiation GO:0009913 68 46 1,000 0,02434281 0,15618345 ! pigmentation GO:0043473 100 46 1,000 0,02434281 0,15576807 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,02434281 0,1553549 ! response to calcium ion GO:0051592 81 47 1,000 0,02533851 0,16128165 ! endosome transport GO:0016197 108 47 1,000 0,02533851 0,16085611 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,02533851 0,1604328 ! methylation GO:0032259 90 47 1,000 0,02533851 0,16001172 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02595895 0,16350062 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02595895 0,16307373 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02595895 0,16264906 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02595895 0,16222659 ! neuron fate determination GO:0048664 7 5 0,000 0,02595895 0,16180631 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02595895 0,16138821 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02595895 0,16097226 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02595895 0,16055845 ! polyol transport GO:0015791 12 5 0,000 0,02595895 0,16014676 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02595895 0,15973718 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02595895 0,15932969 ! response to superoxide GO:0000303 10 5 0,000 0,02595895 0,15892427 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02595895 0,15852091 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02595895 0,15811959 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02595895 0,1577203 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02595895 0,15732302 ! female meiosis GO:0007143 7 5 0,000 0,02595895 0,15692773 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02595895 0,15653443 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02595895 0,15614309 ! cobalt ion transport GO:0006824 11 5 0,000 0,02595895 0,15575371 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02595895 0,15536626 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02595895 0,15498074 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02595895 0,15459712 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02595895 0,1542154 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02595895 0,15383556 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02595895 0,15345759 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02595895 0,15308146 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02595895 0,15270718 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02595895 0,15233472 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02595895 0,15196408 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02595895 0,15159524 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02595895 0,15122818 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02595895 0,15086289 ! negative chemotaxis GO:0050919 14 5 0,000 0,02595895 0,15049937 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02595895 0,15013759 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02595895 0,14977755 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02595895 0,14941923 ! behavioral response to pain GO:0048266 9 5 0,000 0,02595895 0,14906262 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02595895 0,14870771 ! Notch receptor processing GO:0007220 8 5 0,000 0,02595895 0,14835448 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02595895 0,14800293 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02595895 0,14765304 ! micturition GO:0060073 9 5 0,000 0,02595895 0,1473048 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02595895 0,14695821 ! copulation GO:0007620 9 5 0,000 0,02595895 0,14661323 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02595895 0,14626988 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02595895 0,14592812 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02595895 0,14558797 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02595895 0,14524939 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02595895 0,14491238 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02595895 0,14457694 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02595895 0,14424304 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02595895 0,14391068 ! grooming behavior GO:0007625 6 5 0,000 0,02595895 0,14357986 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02595895 0,14325054 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02595895 0,14292274 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02595895 0,14259643 ! response to protozoan GO:0001562 10 5 0,000 0,02595895 0,14227161 ! lymph vessel development GO:0001945 10 5 0,000 0,02595895 0,14194827 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02595895 0,14162639 ! endochondral ossification GO:0001958 16 5 0,000 0,02595895 0,14130597 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02595895 0,14098699 ! parathyroid gland development GO:0060017 13 5 0,000 0,02595895 0,14066945 ! anagen GO:0042640 6 5 0,000 0,02595895 0,14035334 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02595895 0,14003865 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02595895 0,13972536 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02595895 0,13941348 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02595895 0,13910298 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02595895 0,13879386 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02595895 0,13848611 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02595895 0,13817973 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02595895 0,1378747 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02595895 0,13757101 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02595895 0,13726865 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02595895 0,13696763 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02595895 0,13666792 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02595895 0,13636951 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02595895 0,13607241 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02595895 0,1357766 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02595895 0,13548208 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02595895 0,13518883 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02595895 0,13489684 ! histidine catabolic process GO:0006548 6 5 0,000 0,02595895 0,13460611 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02595895 0,13431664 ! microvillus organization GO:0032528 7 5 0,000 0,02595895 0,13402841 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,02595895 0,13374141 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02595895 0,13345563 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02595895 0,13317108 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02595895 0,13288774 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02595895 0,1326056 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02595895 0,13232466 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02595895 0,1320449 ! polyol catabolic process GO:0046174 7 5 0,000 0,02595895 0,13176632 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02595895 0,13148892 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02595895 0,13121268 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02595895 0,1309376 ! muscle cell migration GO:0014812 8 5 0,000 0,02595895 0,13066368 ! mitochondrial fission GO:0000266 8 5 0,000 0,02595895 0,13039089 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02595895 0,13011924 ! mRNA transcription GO:0009299 9 5 0,000 0,02595895 0,12984873 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02595895 0,12957933 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02595895 0,12931105 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02595895 0,12904388 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02595895 0,12877781 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02595895 0,12851283 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02595895 0,12824895 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02595895 0,12798614 ! response to food GO:0032094 6 5 0,000 0,02595895 0,12772441 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02595895 0,12746375 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02595895 0,12720415 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02595895 0,1269456 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02595895 0,12668811 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02595895 0,12643165 ! forebrain neuron development GO:0021884 13 5 0,000 0,02595895 0,12617624 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02595895 0,12592185 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02595895 0,12566849 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02595895 0,12541614 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02595895 0,1251648 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02595895 0,12491447 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02595895 0,12466514 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02595895 0,12441681 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02595895 0,12416946 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02595895 0,12392309 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02595895 0,1236777 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02595895 0,12343328 ! basic amino acid transport GO:0015802 11 5 0,000 0,02595895 0,12318982 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02595895 0,12294732 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02595895 0,12270577 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02595895 0,12246517 ! depyrimidination GO:0045008 10 5 0,000 0,02595895 0,12222551 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02595895 0,12198679 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02595895 0,121749 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02595895 0,12151213 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02595895 0,12127619 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02595895 0,12104116 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02595895 0,12080704 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02595895 0,12057382 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02595895 0,1203415 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02595895 0,12011007 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02595895 0,11987953 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02595895 0,11964988 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02595895 0,1194211 ! response to arsenic GO:0046685 10 5 0,000 0,02595895 0,1191932 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02595895 0,11896617 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02595895 0,11873999 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02595895 0,11851468 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02595895 0,11829022 ! response to cadmium ion GO:0046686 7 5 0,000 0,02595895 0,11806661 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02595895 0,11784384 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02595895 0,11762192 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02595895 0,11740082 ! decidualization GO:0046697 11 5 0,000 0,02595895 0,11718056 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02595895 0,11696112 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02595895 0,1167425 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02595895 0,1165247 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02595895 0,1163077 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02595895 0,11609152 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02595895 0,11587614 ! neural tube patterning GO:0021532 7 5 0,000 0,02595895 0,11566155 ! embryonic cleavage GO:0040016 6 5 0,000 0,02595895 0,11544776 ! peroxisome fission GO:0016559 5 5 0,000 0,02595895 0,11523475 ! histone demethylation GO:0016577 10 5 0,000 0,02595895 0,11502254 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02595895 0,1148111 ! mitotic recombination GO:0006312 9 5 0,000 0,02595895 0,11460044 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02595895 0,11439054 ! metaphase plate congression GO:0051310 7 5 0,000 0,02595895 0,11418142 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02595895 0,11397306 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02595895 0,11376546 ! enteric nervous system development GO:0048484 8 5 0,000 0,02595895 0,11355861 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02595895 0,11335252 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02595895 0,11314717 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02595895 0,11294256 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02595895 0,1127387 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02595895 0,11253556 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02595895 0,11233316 ! plasminogen activation GO:0031639 5 5 0,000 0,02595895 0,11213149 ! B cell homeostasis GO:0001782 13 5 0,000 0,02595895 0,11193053 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02595895 0,1117303 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02595895 0,11153078 ! metaphase GO:0051323 8 5 0,000 0,02595895 0,11133197 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02595895 0,11113387 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02595895 0,11093648 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02595895 0,11073978 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02595895 0,11054378 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02595895 0,11034848 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02595895 0,11015386 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02595895 0,10995992 ! response to redox state GO:0051775 5 5 0,000 0,02595895 0,10976667 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02595895 0,1095741 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02595895 0,1093822 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02595895 0,10919097 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02595895 0,10900041 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02595895 0,10881052 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02595895 0,10862128 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02595895 0,1084327 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02595895 0,10824478 ! striatum development GO:0021756 9 5 0,000 0,02595895 0,1080575 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02595895 0,10787088 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02595895 0,10768489 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02595895 0,10749955 ! glial cell migration GO:0008347 11 5 0,000 0,02595895 0,10731484 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02595895 0,10713077 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02595895 0,10694732 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02595895 0,10676451 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02595895 0,10658232 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02595895 0,10640074 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02595895 0,10621979 ! neuroprotection GO:0043526 6 5 0,000 0,02595895 0,10603945 ! neural plate development GO:0001840 8 5 0,000 0,02595895 0,10585972 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02595895 0,1056806 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02595895 0,10550209 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02595895 0,10532418 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02595895 0,10514686 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02595895 0,10497015 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02595895 0,10479402 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02595895 0,10461849 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02595895 0,10444354 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02595895 0,10426918 ! spindle assembly GO:0051225 6 5 0,000 0,02595895 0,1040954 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02595895 0,10392219 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02595895 0,10374956 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02595895 0,10357751 ! drug metabolic process GO:0017144 6 5 0,000 0,02595895 0,10340602 ! stem cell division GO:0017145 11 5 0,000 0,02595895 0,1032351 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02595895 0,10306475 ! organ regeneration GO:0031100 7 5 0,000 0,02595895 0,10289495 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02595895 0,10272572 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02595895 0,10255704 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02595895 0,10238891 ! mitochondrial transport GO:0006839 82 48 1,000 0,02635059 0,10376353 ! cellular component disassembly GO:0022411 86 48 1,000 0,02635059 0,10359398 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 0,02635059 0,10342498 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,02737883 0,10728579 ! peptide metabolic process GO:0006518 76 49 1,000 0,02737883 0,10711134 ! endocrine system development GO:0035270 104 49 1,000 0,02737883 0,10693746 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 0,02737883 0,10676414 GO:0019724|B cell mediated immunity, ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,02737883 0,10659138 ! histone modification GO:0016570 91 50 1,000 0,02842305 0,11047798 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,02842305 0,11029979 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,02842305 0,11012217 ! positive regulation of binding GO:0051099 78 51 1,000 0,02948306 0,1140454 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,03055865 0,11801623 ! membrane fusion GO:0006944 110 52 1,000 0,03055865 0,1178271 ! covalent chromatin modification GO:0016569 101 52 1,000 0,03055865 0,11763858 ! amino acid activation GO:0043038 92 52 1,000 0,03055865 0,11745066 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 1,000 0,03055865 0,11726334 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03106982 0,11903501 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03106982 0,11884577 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03106982 0,11865712 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03106982 0,11846908 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03106982 0,11828163 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03106982 0,11809477 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03106982 0,1179085 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03106982 0,11772282 ! sleep GO:0030431 13 6 0,000 0,03106982 0,11753772 ! response to oxygen radical GO:0000305 11 6 0,000 0,03106982 0,1173532 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03106982 0,11716926 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03106982 0,1169859 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03106982 0,11680311 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03106982 0,11662089 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03106982 0,11643923 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03106982 0,11625815 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03106982 0,11607762 ! forebrain regionalization GO:0021871 8 6 0,000 0,03106982 0,11589766 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03106982 0,11571825 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03106982 0,11553939 ! response to zinc ion GO:0010043 9 6 0,000 0,03106982 0,11536109 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03106982 0,11518334 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,03106982 0,11500614 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03106982 0,11482947 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03106982 0,11465336 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03106982 0,11447778 ! malate metabolic process GO:0006108 11 6 0,000 0,03106982 0,11430273 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03106982 0,11412823 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03106982 0,11395425 ! protein refolding GO:0042026 15 6 0,000 0,03106982 0,1137808 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03106982 0,11360788 ! opsonization GO:0008228 8 6 0,000 0,03106982 0,11343549 ! mating behavior GO:0007617 7 6 0,000 0,03106982 0,11326362 ! neuron remodeling GO:0016322 15 6 0,000 0,03106982 0,11309227 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03106982 0,11292143 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03106982 0,11275111 ! equilibrioception GO:0050957 14 6 0,000 0,03106982 0,11258131 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03106982 0,11241201 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03106982 0,11224322 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03106982 0,11207494 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03106982 0,11190717 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03106982 0,11173989 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03106982 0,11157312 ! toxin metabolic process GO:0009404 11 6 0,000 0,03106982 0,11140684 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03106982 0,11124105 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03106982 0,11107576 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03106982 0,11091096 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03106982 0,11074665 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03106982 0,11058282 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03106982 0,11041948 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03106982 0,11025662 ! thymic T cell selection GO:0045061 12 6 0,000 0,03106982 0,11009424 ! protein lipoylation GO:0009249 10 6 0,000 0,03106982 0,10993234 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03106982 0,10977091 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03106982 0,10960995 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03106982 0,10944947 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03106982 0,10928946 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03106982 0,10912991 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03106982 0,10897083 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03106982 0,10881221 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03106982 0,10865405 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03106982 0,10849635 ! hyperosmotic response GO:0006972 9 6 0,000 0,03106982 0,10833911 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03106982 0,10818233 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03106982 0,10802599 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03106982 0,10787011 ! urea metabolic process GO:0019627 7 6 0,000 0,03106982 0,10771468 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03106982 0,10755969 ! neutrophil activation GO:0042119 8 6 0,000 0,03106982 0,10740515 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03106982 0,10725106 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03106982 0,1070974 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03106982 0,10694419 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03106982 0,10679141 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03106982 0,10663907 ! neuron apoptosis GO:0051402 9 6 0,000 0,03106982 0,10648716 ! nucleoside salvage GO:0043174 9 6 0,000 0,03106982 0,10633569 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03106982 0,10618464 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03106982 0,10603403 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03106982 0,10588384 ! carnitine transport GO:0015879 10 6 0,000 0,03106982 0,10573407 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03106982 0,10558473 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03106982 0,10543581 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03106982 0,10528731 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03106982 0,10513922 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03106982 0,10499156 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03106982 0,1048443 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03106982 0,10469746 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03106982 0,10455103 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03106982 0,10440501 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03106982 0,1042594 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03106982 0,10411419 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 14 6 0,000 0,03106982 0,10396939 ! response to UV-C GO:0010225 11 6 0,000 0,03106982 0,10382498 ! astrocyte development GO:0014002 15 6 0,000 0,03106982 0,10368098 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03106982 0,10353738 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03106982 0,10339417 ! interaction with symbiont GO:0051702 13 6 0,000 0,03106982 0,10325136 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03106982 0,10310895 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03106982 0,10296693 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03106982 0,10282529 ! response to copper ion GO:0046688 10 6 0,000 0,03106982 0,10268405 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03106982 0,10254319 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,03106982 0,10240272 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03106982 0,10226264 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03106982 0,10212293 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03106982 0,10198361 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03106982 0,10184467 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03106982 0,10170611 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03106982 0,10156792 ! hair follicle maturation GO:0048820 7 6 0,000 0,03106982 0,10143011 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03106982 0,10129267 ! Schwann cell development GO:0014044 15 6 0,000 0,03106982 0,1011556 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03106982 0,1010189 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03106982 0,10088257 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03106982 0,10074661 ! subpallium development GO:0021544 10 6 0,000 0,03106982 0,10061102 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03106982 0,10047579 ! histone ubiquitination GO:0016574 8 6 0,000 0,03106982 0,10034092 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03106982 0,10020642 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03106982 0,10007227 ! G2 phase GO:0051319 16 6 0,000 0,03106982 0,09993849 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03106982 0,09980506 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03106982 0,09967198 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03106982 0,09953926 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03106982 0,0994069 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03106982 0,09927488 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03106982 0,09914322 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03106982 0,0990119 ! receptor internalization GO:0031623 10 6 0,000 0,03106982 0,09888094 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03106982 0,09875031 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03106982 0,09862004 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03106982 0,0984901 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03106982 0,09836051 ! protein deubiquitination GO:0016579 14 6 0,000 0,03106982 0,09823126 ! protein destabilization GO:0031648 9 6 0,000 0,03106982 0,09810235 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03106982 0,09797377 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03106982 0,09784553 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03106982 0,09771763 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03106982 0,09759006 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03106982 0,09746283 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03106982 0,09733592 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03106982 0,09720935 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03106982 0,0970831 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03106982 0,09695718 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03106982 0,09683159 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03106982 0,09670632 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03106982 0,09658138 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03106982 0,09645676 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03106982 0,09633246 ! catecholamine transport GO:0051937 9 6 0,000 0,03106982 0,09620848 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03106982 0,09608482 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03106982 0,09596147 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03106982 0,09583845 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03106982 0,09571573 ! maternal placenta development GO:0001893 12 6 0,000 0,03106982 0,09559333 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03106982 0,09547125 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03106982 0,09534947 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,03106982 0,09522801 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03106982 0,09510685 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03106982 0,09498601 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03106982 0,09486547 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03106982 0,09474523 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,03164964 0,09639119 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,03275585 0,09963409 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,03275585 0,09950829 ! heterocycle catabolic process GO:0046700 85 54 1,000 0,03275585 0,09938281 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,03387707 0,10265521 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,03387707 0,10252609 ! aging GO:0007568 103 55 1,000 0,03387707 0,10239729 ! heart morphogenesis GO:0003007 97 55 1,000 0,03387707 0,10226881 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,03387707 0,10214065 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,03501314 0,10543381 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,03501314 0,10530201 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,03501314 0,10517055 ! tRNA transcription GO:0009304 14 7 0,000 0,03615404 0,10846212 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03615404 0,10832705 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03615404 0,10819232 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03615404 0,10805792 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03615404 0,10792385 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03615404 0,10779011 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03615404 0,10765671 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03615404 0,10752364 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03615404 0,10739089 ! prostate gland development GO:0030850 13 7 0,000 0,03615404 0,10725847 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03615404 0,10712638 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03615404 0,10699462 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03615404 0,10686317 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03615404 0,10673205 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03615404 0,10660125 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03615404 0,10647077 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03615404 0,10634061 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,03615404 0,10621077 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03615404 0,10608125 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03615404 0,10595204 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03615404 0,10582314 ! glycolipid transport GO:0046836 10 7 0,000 0,03615404 0,10569456 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03615404 0,10556629 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03615404 0,10543833 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03615404 0,10531068 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03615404 0,10518334 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03615404 0,10505631 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03615404 0,10492958 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03615404 0,10480316 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03615404 0,10467704 ! mRNA stabilization GO:0048255 18 7 0,000 0,03615404 0,10455123 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,03615404 0,10442572 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03615404 0,10430051 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03615404 0,1041756 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03615404 0,10405098 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03615404 0,10392667 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03615404 0,10380265 ! lipoprotein transport GO:0042953 14 7 0,000 0,03615404 0,10367893 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03615404 0,1035555 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03615404 0,10343237 ! rhythmic behavior GO:0007622 15 7 0,000 0,03615404 0,10330953 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03615404 0,10318698 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03615404 0,10306472 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03615404 0,10294275 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03615404 0,10282107 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03615404 0,10269967 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03615404 0,10257856 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03615404 0,10245774 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03615404 0,1023372 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03615404 0,10221695 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03615404 0,10209698 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03615404 0,10197728 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03615404 0,10185787 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03615404 0,10173874 ! spinal cord patterning GO:0021511 13 7 0,000 0,03615404 0,10161989 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03615404 0,10150131 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03615404 0,10138301 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03615404 0,10126499 ! adrenal gland development GO:0030325 17 7 0,000 0,03615404 0,10114724 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03615404 0,10102976 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03615404 0,10091256 ! ovulation GO:0030728 9 7 0,000 0,03615404 0,10079562 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03615404 0,10067896 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03615404 0,10056257 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03615404 0,10044645 ! microtubule nucleation GO:0007020 20 7 0,000 0,03615404 0,10033059 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03615404 0,100215 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03615404 0,10009968 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03615404 0,09998462 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03615404 0,09986983 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03615404 0,0997553 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03615404 0,09964103 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03615404 0,09952703 ! galactose metabolic process GO:0006012 13 7 0,000 0,03615404 0,09941328 ! vesicle fusion GO:0006906 17 7 0,000 0,03615404 0,0992998 ! response to dietary excess GO:0002021 8 7 0,000 0,03615404 0,09918657 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03615404 0,0990736 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03615404 0,09896089 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03615404 0,09884843 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03615404 0,09873623 ! organ growth GO:0035265 15 7 0,000 0,03615404 0,09862429 ! purine salvage GO:0043101 10 7 0,000 0,03615404 0,0985126 ! nucleoside transport GO:0015858 8 7 0,000 0,03615404 0,09840116 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03615404 0,09828997 ! parturition GO:0007567 14 7 0,000 0,03615404 0,09817903 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03615404 0,09806835 ! rRNA modification GO:0000154 14 7 0,000 0,03615404 0,09795791 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03615404 0,09784772 ! spindle checkpoint GO:0031577 15 7 0,000 0,03615404 0,09773778 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03615404 0,09762808 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03615404 0,09751864 ! macrophage differentiation GO:0030225 11 7 0,000 0,03615404 0,09740943 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03615404 0,09730047 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03615404 0,09719176 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03615404 0,09708328 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03615404 0,09697505 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03615404 0,09686706 ! fibrinolysis GO:0042730 10 7 0,000 0,03615404 0,09675931 ! eating behavior GO:0042755 7 7 0,000 0,03615404 0,0966518 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03615404 0,09654453 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03615404 0,0964375 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03615404 0,0963307 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03615404 0,09622414 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03615404 0,09611782 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03615404 0,09601172 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03615404 0,09590587 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03615404 0,09580025 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03615404 0,09569485 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03615404 0,0955897 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03615404 0,09548477 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03615404 0,09538007 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03615404 0,0952756 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03615404 0,09517136 ! regulation of meiosis GO:0040020 12 7 0,000 0,03615404 0,09506735 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03615404 0,09496356 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03615404 0,09486 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03615404 0,09475667 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03615404 0,09465356 ! transcription termination GO:0006353 13 7 0,000 0,03615404 0,09455068 ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03615404 0,09444802 ! axonal fasciculation GO:0007413 18 7 0,000 0,03615404 0,09434558 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03615404 0,09424336 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03615404 0,09414137 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03615404 0,09403959 ! diuresis GO:0030146 12 7 0,000 0,03615404 0,09393804 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03615404 0,0938367 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03615404 0,09373558 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03615404 0,09363469 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03615404 0,093534 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03615404 0,09343354 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03615404 0,09333329 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03615404 0,09323325 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03615404 0,09313343 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03615404 0,09303382 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03615404 0,09293443 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03615404 0,09283524 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03615404 0,09273627 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03615404 0,09263751 ! lymph node development GO:0048535 10 7 0,000 0,03615404 0,09253896 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03615404 0,09244062 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03615404 0,09234249 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03615404 0,09224456 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03615404 0,09214685 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03615404 0,09204934 ! adult feeding behavior GO:0008343 9 7 0,000 0,03615404 0,09195203 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03615404 0,09185493 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03615404 0,09175804 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03615404 0,09166135 ! muscle adaptation GO:0043500 14 7 0,000 0,03615404 0,09156487 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03615404 0,09146858 ! retina homeostasis GO:0001895 12 7 0,000 0,03615404 0,0913725 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03615404 0,09127662 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03615404 0,09118095 ! protein prenylation GO:0018342 18 7 0,000 0,03615404 0,09108547 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03615404 0,09099019 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03615404 0,09089511 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03615404 0,09080023 ! muscle fiber development GO:0048747 112 57 1,000 0,03616386 0,09073017 ! lipid modification GO:0030258 97 57 1,000 0,03616386 0,09063566 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,03616386 0,09054135 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,03616386 0,09044723 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,03732904 0,09326446 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,03850852 0,09611151 ! DNA catabolic process GO:0006308 86 59 1,000 0,03850852 0,09601191 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,03850852 0,09591252 ! establishment of organelle localization GO:0051656 109 59 1,000 0,03850852 0,09581334 ! nucleoside metabolic process GO:0009116 81 60 1,000 0,0397021 0,09868106 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04121175 0,10232763 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04121175 0,10222214 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04121175 0,10211686 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04121175 0,1020118 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04121175 0,10190696 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04121175 0,10180233 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04121175 0,10169792 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04121175 0,10159372 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04121175 0,10148974 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04121175 0,10138597 ! meiotic prophase I GO:0007128 13 8 0,000 0,04121175 0,1012824 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04121175 0,10117906 ! oligopeptide transport GO:0006857 15 8 0,000 0,04121175 0,10107592 ! UTP metabolic process GO:0046051 8 8 0,000 0,04121175 0,10097299 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04121175 0,10087027 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04121175 0,10076776 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04121175 0,10066546 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04121175 0,10056336 ! succinate metabolic process GO:0006105 14 8 0,000 0,04121175 0,10046147 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04121175 0,10035979 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04121175 0,10025832 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04121175 0,10015704 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04121175 0,10005598 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04121175 0,09995512 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04121175 0,09985446 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04121175 0,099754 ! reflex GO:0060004 16 8 0,000 0,04121175 0,09965374 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04121175 0,09955369 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04121175 0,09945384 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04121175 0,09935418 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04121175 0,09925473 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04121175 0,09915547 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04121175 0,09905642 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04121175 0,09895756 ! pigment granule organization GO:0048753 16 8 0,000 0,04121175 0,0988589 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04121175 0,09876043 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04121175 0,09866216 ! histidine metabolic process GO:0006547 16 8 0,000 0,04121175 0,09856409 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04121175 0,09846621 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04121175 0,09836853 ! glycine catabolic process GO:0006546 13 8 0,000 0,04121175 0,09827103 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04121175 0,09817374 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04121175 0,09807663 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04121175 0,09797972 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04121175 0,097883 ! melanin metabolic process GO:0006582 15 8 0,000 0,04121175 0,09778646 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04121175 0,09769012 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04121175 0,09759397 ! macrophage activation GO:0042116 12 8 0,000 0,04121175 0,09749801 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04121175 0,09740223 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,04121175 0,09730665 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04121175 0,09721125 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04121175 0,09711604 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04121175 0,09702101 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04121175 0,09692617 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04121175 0,09683152 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04121175 0,09673705 ! osteoblast development GO:0002076 16 8 0,000 0,04121175 0,09664276 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04121175 0,09654866 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04121175 0,09645474 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04121175 0,096361 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04121175 0,09626745 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04121175 0,09617408 ! response to UV-B GO:0010224 16 8 0,000 0,04121175 0,09608089 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04121175 0,09598787 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04121175 0,09589504 ! intermediate filament organization GO:0045109 12 8 0,000 0,04121175 0,09580239 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04121175 0,09570992 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,04121175 0,09561762 ! cellular extravasation GO:0045123 12 8 0,000 0,04121175 0,0955255 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04121175 0,09543357 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04121175 0,0953418 ! response to antibiotic GO:0046677 11 8 0,000 0,04121175 0,09525022 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04121175 0,0951588 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04121175 0,09506757 ! DNA topological change GO:0006265 12 8 0,000 0,04121175 0,09497651 ! response to tropane GO:0014073 15 8 0,000 0,04121175 0,09488562 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04121175 0,09479491 ! melanosome transport GO:0032402 13 8 0,000 0,04121175 0,09470437 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04121175 0,094614 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04121175 0,09452381 ! mast cell activation GO:0045576 14 8 0,000 0,04121175 0,09443378 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04121175 0,09434393 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04121175 0,09425425 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04121175 0,09416474 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04121175 0,0940754 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04121175 0,09398623 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04121175 0,09389723 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04121175 0,0938084 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04121175 0,09371973 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04121175 0,09363123 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04121175 0,0935429 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04121175 0,09345474 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04121175 0,09336674 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04121175 0,0932789 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04121175 0,09319124 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04121175 0,09310373 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04121175 0,09301639 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04121175 0,09292922 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04121175 0,0928422 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04121175 0,09275535 ! hormone catabolic process GO:0042447 17 8 0,000 0,04121175 0,09266867 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04121175 0,09258214 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04121175 0,09249578 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04121175 0,09240958 ! blastocyst growth GO:0001832 19 8 0,000 0,04121175 0,09232353 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04121175 0,09223765 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04121175 0,09215193 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04121175 0,09206636 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04121175 0,09198096 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04121175 0,09189571 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04121175 0,09181062 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04121175 0,09172569 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04121175 0,09164092 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04121175 0,0915563 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04121175 0,09147184 GO:0006043|glucosamine catabolic process, ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04121175 0,09138753 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04121175 0,09130338 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04121175 0,09121939 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04121175 0,09113555 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04121175 0,09105186 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04121175 0,09096832 ! ear development GO:0043583 103 62 1,000 0,04213089 0,09291193 ! viral reproductive process GO:0022415 126 62 1,000 0,04213089 0,09282685 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,04213089 0,09274192 ! regulation of mitosis GO:0007088 105 63 1,000 0,04336573 0,0953729 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,04336573 0,09528581 ! detection of external stimulus GO:0009581 91 63 1,000 0,04336573 0,09519887 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,04336573 0,09511208 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,04461398 0,0977607 ! single fertilization GO:0007338 75 64 1,000 0,04461398 0,09767174 ! myeloid cell differentiation GO:0030099 111 65 1,000 0,04587547 0,10034216 ! axon extension GO:0048675 15 9 0,000 0,04624309 0,10105438 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,04624309 0,10096268 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,04624309 0,10087114 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,04624309 0,10077978 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04624309 0,10068857 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,04624309 0,10059753 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,04624309 0,10050666 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,04624309 0,10041595 ! phosphate transport GO:0006817 19 9 0,000 0,04624309 0,1003254 ! reproductive behavior GO:0019098 19 9 0,000 0,04624309 0,10023502 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04624309 0,1001448 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,04624309 0,10005474 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,04624309 0,09996484 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 9 9 0,000 0,04624309 0,09987511 ! RNA methylation GO:0001510 15 9 0,000 0,04624309 0,09978554 ! elastic fiber assembly GO:0048251 15 9 0,000 0,04624309 0,09969612 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,04624309 0,09960687 ! artery development GO:0060840 24 9 0,000 0,04624309 0,09951777 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,04624309 0,09942884 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,04624309 0,09934006 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,04624309 0,09925145 ! chemosensory behavior GO:0007635 20 9 0,000 0,04624309 0,09916299 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,04624309 0,09907469 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04624309 0,09898654 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,04624309 0,09889855 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,04624309 0,09881072 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,04624309 0,09872305 ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04624309 0,09863553 ! protein targeting to ER GO:0045047 22 9 0,000 0,04624309 0,09854816 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,04624309 0,09846095 ! T cell selection GO:0045058 23 9 0,000 0,04624309 0,09837389 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,04624309 0,09828699 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,04624309 0,09820024 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,04624309 0,09811364 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04624309 0,0980272 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,04624309 0,09794091 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04624309 0,09785477 ! mannose metabolic process GO:0006013 13 9 0,000 0,04624309 0,09776878 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,04624309 0,09768294 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,04624309 0,09759726 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,04624309 0,09751172 ! receptor clustering GO:0043113 18 9 0,000 0,04624309 0,09742633 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,04624309 0,0973411 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04624309 0,09725601 ! ruffle organization GO:0031529 15 9 0,000 0,04624309 0,09717107 ! retinol metabolic process GO:0042572 18 9 0,000 0,04624309 0,09708628 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,04624309 0,09700163 ! behavioral fear response GO:0001662 22 9 0,000 0,04624309 0,09691714 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,04624309 0,09683279 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,04624309 0,09674858 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,04624309 0,09666453 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,04624309 0,09658062 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,04624309 0,09649685 ! segment specification GO:0007379 13 9 0,000 0,04624309 0,09641323 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04624309 0,09632976 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,04624309 0,09624643 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04624309 0,09616324 ! response to amine stimulus GO:0014075 13 9 0,000 0,04624309 0,0960802 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04624309 0,0959973 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,04624309 0,09591455 ! erythrocyte development GO:0048821 15 9 0,000 0,04624309 0,09583193 ! gas homeostasis GO:0033483 16 9 0,000 0,04624309 0,09574946 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,04624309 0,09566713 ! renal water homeostasis GO:0003091 14 9 0,000 0,04624309 0,09558494 ! postreplication repair GO:0006301 22 9 0,000 0,04624309 0,09550289 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,04624309 0,09542099 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,04624309 0,09533922 ! icosanoid secretion GO:0032309 15 9 0,000 0,04624309 0,0952576 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,04624309 0,09517611 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04624309 0,09509476 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,04624309 0,09501355 ! regulation of cell division GO:0051302 15 9 0,000 0,04624309 0,09493248 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,04624309 0,09485155 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,04624309 0,09477076 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04624309 0,0946901 ! sterol catabolic process GO:0016127 11 9 0,000 0,04624309 0,09460959 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04624309 0,0945292 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,04624309 0,09444896 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,04624309 0,09436885 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,04624309 0,09428887 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,04624309 0,09420904 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,04624309 0,09412933 ! musculoskeletal movement GO:0050881 14 9 0,000 0,04624309 0,09404977 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,04624309 0,09397033 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,04624309 0,09389103 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04624309 0,09381187 ! purine base metabolic process GO:0006144 21 9 0,000 0,04624309 0,09373283 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,04624309 0,09365393 ! pigment granule transport GO:0051904 17 9 0,000 0,04624309 0,09357517 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,04624309 0,09349653 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,04624309 0,09341803 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04624309 0,09333966 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,04624309 0,09326142 ! mitochondrion localization GO:0051646 15 9 0,000 0,04624309 0,09318331 ! cell projection assembly GO:0030031 120 66 1,000 0,04715001 0,09493131 ! activation of MAPK activity GO:0000187 115 67 1,000 0,04843744 0,09744187 ! lung development GO:0030324 144 67 1,000 0,04843744 0,09736047 ! chromosome segregation GO:0007059 113 67 1,000 0,04843744 0,0972792 ! adaptive immune response GO:0002250 119 67 1,000 0,04843744 0,09719807 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,04973759 0,09972387 ! viral reproduction GO:0016032 134 68 1,000 0,04973759 0,09964084 ! regulation of lipase activity GO:0060191 130 68 1,000 0,04973759 0,09955794 ! protein maturation by peptide bond cleavage GO:0051605 105 68 1,000 0,04973759 0,09947519 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,0510503 0,1020158 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,05124819 0,10232626 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05124819 0,10224141 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05124819 0,10215671 ! synapsis GO:0007129 13 10 0,000 0,05124819 0,10207214 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05124819 0,10198771 ! N-glycan processing GO:0006491 20 10 0,000 0,05124819 0,10190343 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,05124819 0,10181928 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,05124819 0,10173527 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05124819 0,1016514 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05124819 0,10156767 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05124819 0,10148407 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05124819 0,10140061 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05124819 0,10131729 ! androgen metabolic process GO:0008209 17 10 0,000 0,05124819 0,10123411 ! phospholipid efflux GO:0033700 16 10 0,000 0,05124819 0,10115106 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05124819 0,10106815 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05124819 0,10098538 ! lung alveolus development GO:0048286 26 10 0,000 0,05124819 0,10090274 ! pathogenesis GO:0009405 13 10 0,000 0,05124819 0,10082023 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05124819 0,10073786 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05124819 0,10065563 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,05124819 0,10057353 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05124819 0,10049156 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,05124819 0,10040973 ! endoderm development GO:0007492 16 10 0,000 0,05124819 0,10032803 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05124819 0,10024646 ! arginine catabolic process GO:0006527 13 10 0,000 0,05124819 0,10016503 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05124819 0,10008372 ! proline metabolic process GO:0006560 13 10 0,000 0,05124819 0,10000255 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05124819 0,09992151 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,05124819 0,0998406 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05124819 0,09975983 ! V(D)J recombination GO:0033151 28 10 0,000 0,05124819 0,09967918 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05124819 0,09959866 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05124819 0,09951828 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05124819 0,09943802 ! B cell proliferation GO:0042100 18 10 0,000 0,05124819 0,09935789 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05124819 0,0992779 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05124819 0,09919803 ! multicellular organism growth GO:0035264 18 10 0,000 0,05124819 0,09911828 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05124819 0,09903867 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05124819 0,09895919 ! epithelial cell development GO:0002064 20 10 0,000 0,05124819 0,09887983 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05124819 0,0988006 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05124819 0,09872149 ! macroautophagy GO:0016236 17 10 0,000 0,05124819 0,09864252 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05124819 0,09856367 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05124819 0,09848494 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05124819 0,09840634 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05124819 0,09832787 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05124819 0,09824952 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05124819 0,09817129 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05124819 0,0980932 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05124819 0,09801522 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,05124819 0,09793737 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05124819 0,09785964 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05124819 0,09778204 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05124819 0,09770455 ! response to dsRNA GO:0043331 20 10 0,000 0,05124819 0,09762719 ! DNA ligation GO:0006266 19 10 0,000 0,05124819 0,09754996 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05124819 0,09747284 ! melanosome localization GO:0032400 16 10 0,000 0,05124819 0,09739585 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05124819 0,09731898 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05124819 0,09724223 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05124819 0,0971656 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05124819 0,09708909 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05124819 0,0970127 ! mRNA cleavage GO:0006379 17 10 0,000 0,05124819 0,09693644 ! protein sumoylation GO:0016925 15 10 0,000 0,05124819 0,09686029 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05124819 0,09678426 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05124819 0,09670835 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05124819 0,09663256 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05124819 0,09655689 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05124819 0,09648134 ! salivary gland development GO:0007431 27 10 0,000 0,05124819 0,0964059 ! prophase GO:0051324 15 10 0,000 0,05124819 0,09633058 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05124819 0,09625538 ! apical protein localization GO:0045176 15 10 0,000 0,05124819 0,0961803 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05124819 0,09610534 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05124819 0,09603049 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,05124819 0,09595576 ! midbrain development GO:0030901 13 10 0,000 0,05124819 0,09588114 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05124819 0,09580664 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05124819 0,09573226 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05124819 0,09565799 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05124819 0,09558383 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05124819 0,0955098 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05124819 0,09543587 ! detection of calcium ion GO:0005513 23 10 0,000 0,05124819 0,09536206 ! oocyte development GO:0048599 17 10 0,000 0,05124819 0,09528837 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05124819 0,09521478 ! blastocyst formation GO:0001825 17 10 0,000 0,05124819 0,09514132 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05124819 0,09506796 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05124819 0,09499472 ! activation of innate immune response GO:0002218 12 10 0,000 0,05124819 0,09492159 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05124819 0,09484857 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05124819 0,09477567 ! response to nicotine GO:0035094 20 10 0,000 0,05124819 0,09470288 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05124819 0,0946302 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05124819 0,09455763 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05124819 0,09448517 ! respiratory tube development GO:0030323 150 70 1,000 0,0523754 0,09648944 ! humoral immune response GO:0006959 109 71 1,000 0,05371272 0,09887743 ! B cell activation GO:0042113 160 71 1,000 0,05371272 0,09880184 ! acute inflammatory response GO:0002526 113 72 1,000 0,05506211 0,10120659 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,05506211 0,10112933 ! carbohydrate transport GO:0008643 110 72 1,000 0,05506211 0,10105219 ! respiratory system development GO:0060541 153 72 1,000 0,05506211 0,10097517 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,05622719 0,10303322 ! respiratory burst GO:0045730 17 11 0,000 0,05622719 0,10295481 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,05622719 0,10287652 ! neuron fate specification GO:0048665 17 11 0,000 0,05622719 0,10279835 ! telencephalon cell migration GO:0022029 20 11 0,000 0,05622719 0,10272029 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,05622719 0,10264235 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,05622719 0,10256454 ! thyroid gland development GO:0030878 26 11 0,000 0,05622719 0,10248684 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,05622719 0,10240925 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,05622719 0,10233179 ! response to pain GO:0048265 24 11 0,000 0,05622719 0,10225444 ! T cell proliferation GO:0042098 26 11 0,000 0,05622719 0,10217721 ! blood vessel remodeling GO:0001974 29 11 0,000 0,05622719 0,10210009 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,05622719 0,10202309 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,05622719 0,10194621 ! ventral spinal cord development GO:0021517 21 11 0,000 0,05622719 0,10186944 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05622719 0,10179279 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05622719 0,10171626 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,05622719 0,10163984 ! melanocyte differentiation GO:0030318 21 11 0,000 0,05622719 0,10156353 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,05622719 0,10148734 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,05622719 0,10141126 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,05622719 0,1013353 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,05622719 0,10125945 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,05622719 0,10118371 ! UV protection GO:0009650 19 11 0,000 0,05622719 0,10110809 ! adult heart development GO:0007512 14 11 0,000 0,05622719 0,10103258 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05622719 0,10095718 ! temperature homeostasis GO:0001659 17 11 0,000 0,05622719 0,1008819 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,05622719 0,10080672 ! negative regulation of ossification GO:0030279 26 11 0,000 0,05622719 0,10073166 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,05622719 0,10065671 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,05622719 0,10058188 ! regulation of organ growth GO:0046620 13 11 0,000 0,05622719 0,10050715 ! pigment granule localization GO:0051875 20 11 0,000 0,05622719 0,10043253 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,05622719 0,10035803 ! vasoconstriction GO:0042310 18 11 0,000 0,05622719 0,10028363 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05622719 0,10020935 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,05622719 0,10013518 ! snRNA metabolic process GO:0016073 24 11 0,000 0,05622719 0,10006111 GO:0016180|snRNA processing, ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,05622719 0,09998716 GO:0006809|nitric oxide biosynthetic process, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,05622719 0,09991331 ! zymogen activation GO:0031638 15 11 0,000 0,05622719 0,09983957 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,05622719 0,09976595 ! neuroblast proliferation GO:0007405 24 11 0,000 0,05622719 0,09969243 ! nucleosome positioning GO:0016584 15 11 0,000 0,05622719 0,09961902 ! regulation of isotype switching GO:0045191 22 11 0,000 0,05622719 0,09954571 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,05622719 0,09947252 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,05622719 0,09939943 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,05622719 0,09932645 ! acid secretion GO:0046717 18 11 0,000 0,05622719 0,09925358 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05622719 0,09918081 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,05622719 0,09910815 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,05622719 0,0990356 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,05622719 0,09896315 ! oocyte differentiation GO:0009994 18 11 0,000 0,05622719 0,09889081 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,05622719 0,09881857 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,05622719 0,09874644 ! cholesterol efflux GO:0033344 19 11 0,000 0,05622719 0,09867441 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,05622719 0,09860249 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05622719 0,09853068 ! germ cell migration GO:0008354 25 11 0,000 0,05622719 0,09845897 ! embryonic gut development GO:0048566 15 11 0,000 0,05622719 0,09838736 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,05622719 0,09831586 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,05622719 0,09824446 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,05622719 0,09817317 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,05622719 0,09810197 ! defense response to fungus GO:0050832 13 11 0,000 0,05622719 0,09803089 ! developmental induction GO:0031128 19 11 0,000 0,05622719 0,0979599 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,05622719 0,09788902 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05622719 0,09781824 ! sequestering of metal ion GO:0051238 14 11 0,000 0,05622719 0,09774756 ! lamellipodium assembly GO:0030032 20 11 0,000 0,05622719 0,09767698 ! nucleus localization GO:0051647 19 11 0,000 0,05622719 0,09760651 ! regulation of synapse organization GO:0050807 17 11 0,000 0,05622719 0,09753614 ! learning or memory GO:0007611 147 73 1,000 0,05642339 0,09780596 ! axon guidance GO:0007411 139 73 1,000 0,05642339 0,09773555 ! fertilization GO:0009566 90 73 1,000 0,05642339 0,09766524 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,05779642 0,09996993 GO:0090046|regulation of transcription regulator activity, ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,05779642 0,09989811 ! eye development GO:0001654 143 74 1,000 0,05779642 0,0998264 ! organelle localization GO:0051640 136 74 1,000 0,05779642 0,09975479 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,05918102 0,10207135 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,05918102 0,10199824 ! regulation of catabolic process GO:0009894 161 76 1,000 0,06057705 0,10432955 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06118023 0,10529301 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06118023 0,10521775 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06118023 0,10514259 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06118023 0,10506754 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06118023 0,1049926 ! cartilage condensation GO:0001502 20 12 0,000 0,06118023 0,10491777 ! mating GO:0007618 17 12 0,000 0,06118023 0,10484304 ! protein complex disassembly GO:0043241 27 12 0,000 0,06118023 0,10476842 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,06118023 0,1046939 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,06118023 0,10461949 ! hippocampus development GO:0021766 26 12 0,000 0,06118023 0,10454519 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,06118023 0,10447099 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06118023 0,1043969 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06118023 0,10432291 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06118023 0,10424903 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06118023 0,10417525 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06118023 0,10410158 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06118023 0,10402801 ! drug transport GO:0015893 16 12 0,000 0,06118023 0,10395454 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06118023 0,10388118 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,06118023 0,10380792 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06118023 0,10373476 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06118023 0,10366171 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06118023 0,10358876 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06118023 0,10351591 ! forebrain cell migration GO:0021885 21 12 0,000 0,06118023 0,10344317 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06118023 0,10337053 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06118023 0,10329798 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06118023 0,10322555 ! entry into host cell GO:0030260 32 12 0,000 0,06118023 0,10315321 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,06118023 0,10308097 ! monoamine transport GO:0015844 18 12 0,000 0,06118023 0,10300884 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06118023 0,1029368 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06118023 0,10286487 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06118023 0,10279304 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06118023 0,1027213 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06118023 0,10264967 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06118023 0,10257814 ! protein homotetramerization GO:0051289 21 12 0,000 0,06118023 0,1025067 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06118023 0,10243537 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06118023 0,10236414 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06118023 0,102293 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06118023 0,10222196 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06118023 0,10215103 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,06118023 0,10208019 ! cranial nerve development GO:0021545 20 12 0,000 0,06118023 0,10200944 ! fucose catabolic process GO:0019317 22 12 0,000 0,06118023 0,1019388 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06118023 0,10186825 ! histone methylation GO:0016571 26 12 0,000 0,06118023 0,10179781 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06118023 0,10172746 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06118023 0,1016572 ! gland morphogenesis GO:0022612 29 12 0,000 0,06118023 0,10158704 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,06118023 0,10151698 ! T cell homeostasis GO:0043029 25 12 0,000 0,06118023 0,10144702 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06118023 0,10137715 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06118023 0,10130738 ! spleen development GO:0048536 22 12 0,000 0,06118023 0,10123771 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,06118023 0,10116813 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06118023 0,10109865 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06118023 0,10102926 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06118023 0,10095996 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06118023 0,10089077 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06118023 0,10082166 ! response to cold GO:0009409 17 12 0,000 0,06118023 0,10075265 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06118023 0,10068374 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06118023 0,10061492 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,06198435 0,10186772 ! blood coagulation GO:0007596 146 78 1,000 0,06340276 0,10412767 GO:0050817|coagulation, ! activation of protein kinase activity GO:0032147 147 79 1,000 0,06483213 0,10640253 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06610743 0,1084216 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,06610743 0,10834774 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06610743 0,10827399 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06610743 0,10820033 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,06610743 0,10812677 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,06610743 0,10805332 ! lipid localization GO:0010876 28 13 0,000 0,06610743 0,10797996 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,06610743 0,10790671 ! organelle fusion GO:0048284 32 13 0,000 0,06610743 0,10783355 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,06610743 0,10776049 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,06610743 0,10768753 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,06610743 0,10761467 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,06610743 0,10754191 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,06610743 0,10746925 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,06610743 0,10739668 ! methionine metabolic process GO:0006555 27 13 0,000 0,06610743 0,10732421 ! plasma membrane organization GO:0007009 24 13 0,000 0,06610743 0,10725184 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,06610743 0,10717957 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,06610743 0,1071074 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,06610743 0,10703532 ! cytokine metabolic process GO:0042107 22 13 0,000 0,06610743 0,10696334 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,06610743 0,10689145 ! exocrine system development GO:0035272 32 13 0,000 0,06610743 0,10681967 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,06610743 0,10674798 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,06610743 0,10667638 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,06610743 0,10660488 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,06610743 0,10653348 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,06610743 0,10646217 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,06610743 0,10639096 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,06610743 0,10631984 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,06610743 0,10624882 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06610743 0,10617789 ! ribosome assembly GO:0042255 17 13 0,000 0,06610743 0,10610706 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,06610743 0,10603632 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,06610743 0,10596568 ! chromatin silencing GO:0006342 26 13 0,000 0,06610743 0,10589513 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,06610743 0,10582467 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06610743 0,10575431 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,06610743 0,10568404 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,06610743 0,10561387 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,06610743 0,10554379 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,06610743 0,1054738 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06610743 0,1054039 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,06610743 0,1053341 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,06610743 0,10526438 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,06610743 0,10519476 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,06610743 0,10512524 ! embryonic placenta development GO:0001892 23 13 0,000 0,06610743 0,1050558 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,06610743 0,10498646 ! insulin secretion GO:0030073 23 13 0,000 0,06610743 0,10491721 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,06610743 0,10484804 ! acrosome reaction GO:0007340 18 13 0,000 0,06610743 0,10477898 ! response to metal ion GO:0010038 140 80 1,000 0,06627231 0,10497114 ! T cell activation GO:0042110 168 81 1,000 0,06772314 0,1071986 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,06772314 0,10712812 ! rRNA transcription GO:0009303 25 14 0,000 0,07100894 0,11225198 ! lactation GO:0007595 26 14 0,000 0,07100894 0,11217828 ! reproductive cellular process GO:0048610 20 14 0,000 0,07100894 0,11210467 ! tRNA modification GO:0006400 20 14 0,000 0,07100894 0,11203116 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,07100894 0,11195774 ! regulation of S phase GO:0033261 23 14 0,000 0,07100894 0,11188442 ! water transport GO:0006833 21 14 0,000 0,07100894 0,1118112 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07100894 0,11173807 ! non-recombinational repair GO:0000726 25 14 0,000 0,07100894 0,11166504 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,07100894 0,11159211 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07100894 0,11151927 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,07100894 0,11144652 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,07100894 0,11137387 ! RNA polyadenylation GO:0043631 30 14 0,000 0,07100894 0,11130131 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07100894 0,11122885 ! palate development GO:0060021 31 14 0,000 0,07100894 0,11115648 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07100894 0,11108421 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,07100894 0,11101203 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,07100894 0,11093994 ! arginine metabolic process GO:0006525 17 14 0,000 0,07100894 0,11086795 ! regulation of heart rate GO:0002027 24 14 0,000 0,07100894 0,11079605 ! organic alcohol transport GO:0015850 29 14 0,000 0,07100894 0,11072425 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,07100894 0,11065254 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,07100894 0,11058092 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,07100894 0,11050939 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07100894 0,11043795 ! L-amino acid transport GO:0015807 30 14 0,000 0,07100894 0,11036661 ! bone mineralization GO:0030282 17 14 0,000 0,07100894 0,11029536 ! stem cell development GO:0048864 43 14 0,000 0,07100894 0,1102242 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,07100894 0,11015314 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,07100894 0,11008216 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07100894 0,11001128 ! cerebellum development GO:0021549 21 14 0,000 0,07100894 0,10994049 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,07100894 0,10986978 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07100894 0,10979917 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,07100894 0,10972865 ! cofactor transport GO:0051181 26 14 0,000 0,07100894 0,10965823 ! NADP metabolic process GO:0006739 24 14 0,000 0,07100894 0,10958789 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,07100894 0,10951764 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07100894 0,10944748 ! intestinal absorption GO:0050892 25 14 0,000 0,07100894 0,10937741 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,07100894 0,10930743 ! oxygen transport GO:0015671 21 14 0,000 0,07100894 0,10923754 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07100894 0,10916774 ! male genitalia development GO:0030539 24 14 0,000 0,07100894 0,10909803 ! regulation of RNA stability GO:0043487 32 14 0,000 0,07100894 0,10902841 ! regulation of axon extension GO:0030516 37 14 0,000 0,07100894 0,10895887 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,07100894 0,10888943 ! hemostasis GO:0007599 158 84 1,000 0,07213808 0,11055045 ! response to unfolded protein GO:0006986 131 85 1,000 0,07363005 0,11276505 ! nucleosome assembly GO:0006334 122 85 1,000 0,07363005 0,11269332 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,07363005 0,11262167 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,07363005 0,11255012 GO:0002696|positive regulation of leukocyte activation, ! response to inorganic substance GO:0010035 153 86 1,000 0,07513194 0,11477298 ! chromatin assembly GO:0031497 124 86 1,000 0,07513194 0,11470015 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,07588489 0,11577618 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07588489 0,11570281 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,07588489 0,11562954 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,07588489 0,11555635 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,07588489 0,11548326 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,07588489 0,11541027 ! copper ion transport GO:0006825 20 15 0,000 0,07588489 0,11533736 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,07588489 0,11526455 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,07588489 0,11519182 ! sulfate transport GO:0008272 23 15 0,000 0,07588489 0,11511919 ! response to cAMP GO:0051591 22 15 0,000 0,07588489 0,11504665 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,07588489 0,11497421 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,07588489 0,11490185 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,07588489 0,11482958 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,07588489 0,11475741 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,07588489 0,11468533 ! response to hexose stimulus GO:0009746 22 15 0,000 0,07588489 0,11461333 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,07588489 0,11454143 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,07588489 0,11446962 ! pituitary gland development GO:0021983 29 15 0,000 0,07588489 0,11439789 ! vesicle coating GO:0006901 33 15 0,000 0,07588489 0,11432626 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,07588489 0,11425472 ! regulation of exocytosis GO:0017157 22 15 0,000 0,07588489 0,11418326 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,07588489 0,1141119 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,07588489 0,11404062 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,07588489 0,11396944 ! regulation of vasodilation GO:0042312 26 15 0,000 0,07588489 0,11389834 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,07588489 0,11382733 ! histone deacetylation GO:0016575 20 15 0,000 0,07588489 0,11375641 ! mRNA splice site selection GO:0006376 38 15 0,000 0,07588489 0,11368558 ! tissue regeneration GO:0042246 26 15 0,000 0,07588489 0,11361483 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,07588489 0,11354418 ! water homeostasis GO:0030104 27 15 0,000 0,07588489 0,11347361 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07588489 0,11340313 ! muscle maintenance GO:0046716 26 15 0,000 0,07588489 0,11333274 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,07588489 0,11326243 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,07588489 0,11319221 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,07588489 0,11312208 ! dopamine metabolic process GO:0042417 35 15 0,000 0,07588489 0,11305204 ! heme biosynthetic process GO:0006783 29 15 0,000 0,07588489 0,11298208 ! cell killing GO:0001906 29 15 0,000 0,07588489 0,11291221 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,07588489 0,11284242 ! detection of bacterium GO:0016045 18 15 0,000 0,07588489 0,11277272 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,07588489 0,11270311 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,07588489 0,11263358 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,07588489 0,11256414 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,07588489 0,11249479 ! peptide hormone processing GO:0016486 23 15 0,000 0,07588489 0,11242552 ! regulation of protein transport GO:0051223 154 87 1,000 0,0766436 0,11347969 GO:0070201|regulation of establishment of protein localization, ! regulation of DNA binding GO:0051101 155 88 1,000 0,0781649 0,11566098 ! gland development GO:0048732 206 88 1,000 0,0781649 0,11558989 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,07969569 0,11778122 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,0807354 0,11924455 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,0807354 0,1191714 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,0807354 0,11909833 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,0807354 0,11902535 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,0807354 0,11895247 ! bone remodeling GO:0046849 27 16 0,000 0,0807354 0,11887967 ! filopodium assembly GO:0046847 32 16 0,000 0,0807354 0,11880696 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,0807354 0,11873434 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,0807354 0,11866181 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,0807354 0,11858936 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,0807354 0,11851701 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,0807354 0,11844474 ! startle response GO:0001964 28 16 0,000 0,0807354 0,11837256 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,0807354 0,11830047 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,0807354 0,11822847 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,0807354 0,11815656 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,0807354 0,11808473 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,0807354 0,11801299 ! protein polyubiquitination GO:0000209 34 16 0,000 0,0807354 0,11794133 ! glutamate metabolic process GO:0006536 22 16 0,000 0,0807354 0,11786977 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,0807354 0,11779829 ! response to osmotic stress GO:0006970 25 16 0,000 0,0807354 0,1177269 ! lysosomal transport GO:0007041 26 16 0,000 0,0807354 0,11765559 ! fructose metabolic process GO:0006000 25 16 0,000 0,0807354 0,11758437 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,0807354 0,11751324 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,0807354 0,11744219 ! intermediate filament-based process GO:0045103 32 16 0,000 0,0807354 0,11737123 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,0807354 0,11730035 ! negative regulation of immune response GO:0050777 35 16 0,000 0,0807354 0,11722956 ! axon cargo transport GO:0008088 43 16 0,000 0,0807354 0,11715885 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,0807354 0,11708823 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,0807354 0,1170177 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,0807354 0,11694725 ! DNA replication initiation GO:0006270 27 16 0,000 0,0807354 0,11687688 ! neuron recognition GO:0008038 35 16 0,000 0,0807354 0,1168066 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,0807354 0,1167364 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,0807354 0,11666629 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,0807354 0,11659627 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,0807354 0,11652632 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,0807354 0,11645646 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,0807354 0,11638669 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,0807354 0,11631699 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,0807354 0,11624738 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,0807354 0,11617786 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,0807354 0,11610841 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,0807354 0,11603905 ! defense response to virus GO:0051607 37 16 0,000 0,0807354 0,11596978 ! ossification GO:0001503 188 90 1,000 0,08123583 0,11661898 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,08123583 0,11654944 ! protein-DNA complex assembly GO:0065004 130 90 1,000 0,08123583 0,11647998 ! bone development GO:0060348 189 91 1,000 0,08278519 0,11863083 ! response to protein stimulus GO:0051789 149 91 1,000 0,08278519 0,11856022 ! nucleosome organization GO:0034728 138 92 1,000 0,08434362 0,12072026 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,08556062 0,12238933 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,08556062 0,1223166 ! metencephalon development GO:0022037 30 17 0,000 0,08556062 0,12224397 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,08556062 0,12217142 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,08556062 0,12209896 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,08556062 0,12202658 ! endothelial cell migration GO:0043542 28 17 0,000 0,08556062 0,12195429 ! inositol metabolic process GO:0006020 28 17 0,000 0,08556062 0,12188209 ! gene silencing by RNA GO:0031047 36 17 0,000 0,08556062 0,12180997 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,08556062 0,12173793 ! glial cell development GO:0021782 27 17 0,000 0,08556062 0,12166598 ! limbic system development GO:0021761 36 17 0,000 0,08556062 0,12159412 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,08556062 0,12152234 ! adult walking behavior GO:0007628 33 17 0,000 0,08556062 0,12145065 ! heart looping GO:0001947 30 17 0,000 0,08556062 0,12137904 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,08556062 0,12130751 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,08556062 0,12123607 ! myoblast differentiation GO:0045445 45 17 0,000 0,08556062 0,12116471 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,08556062 0,12109344 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,08556062 0,12102225 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,08556062 0,12095114 ! glycine metabolic process GO:0006544 28 17 0,000 0,08556062 0,12088012 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,08556062 0,12080918 ! NAD metabolic process GO:0019674 29 17 0,000 0,08556062 0,12073833 ! membrane budding GO:0006900 37 17 0,000 0,08556062 0,12066755 ! DNA integration GO:0015074 29 17 0,000 0,08556062 0,12059686 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,08556062 0,12052626 ! regulation of protein binding GO:0043393 33 17 0,000 0,08556062 0,12045573 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,08556062 0,12038529 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,08556062 0,12031493 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,08556062 0,12024465 ! genitalia development GO:0048806 30 17 0,000 0,08556062 0,12017446 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,08556062 0,12010434 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,08556062 0,12003431 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,08556062 0,11996436 ! steroid catabolic process GO:0006706 31 17 0,000 0,08556062 0,11989449 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,08556062 0,11982471 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,08556062 0,119755 ! gas transport GO:0015669 25 17 0,000 0,08556062 0,11968538 ! organic cation transport GO:0015695 31 17 0,000 0,08556062 0,11961583 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,08556062 0,11954637 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,08556062 0,11947699 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,08556062 0,11940768 ! microspike assembly GO:0030035 36 17 0,000 0,08556062 0,11933846 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,08591099 0,11975773 ! transcription initiation GO:0006352 153 94 1,000 0,08748717 0,12188426 ! regulation of T cell activation GO:0050863 158 94 1,000 0,08748717 0,12181373 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,09036066 0,12574191 ! neuron maturation GO:0042551 42 18 0,000 0,09036066 0,12566923 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,09036066 0,12559663 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,09036066 0,12552411 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,09036066 0,12545168 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,09036066 0,12537933 ! memory GO:0007613 31 18 0,000 0,09036066 0,12530707 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09036066 0,12523488 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,09036066 0,12516279 ! patterning of blood vessels GO:0001569 39 18 0,000 0,09036066 0,12509077 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,09036066 0,12501884 GO:0042744|hydrogen peroxide catabolic process, ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,09036066 0,12494699 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,09036066 0,12487522 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09036066 0,12480354 ! response to retinoic acid GO:0032526 26 18 0,000 0,09036066 0,12473193 ! response to fungus GO:0009620 21 18 0,000 0,09036066 0,12466041 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,09036066 0,12458897 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,09036066 0,12451762 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,09036066 0,12444634 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,09036066 0,12437515 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,09036066 0,12430404 ! vitamin transport GO:0051180 27 18 0,000 0,09036066 0,12423301 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,09036066 0,12416206 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,09036066 0,12409119 GO:0033014|tetrapyrrole biosynthetic process, ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,09036066 0,1240204 ! nerve development GO:0021675 28 18 0,000 0,09036066 0,12394969 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,09036066 0,12387907 ! mRNA transport GO:0051028 169 96 1,000 0,0906654 0,12422605 ! detection of stimulus GO:0051606 151 96 1,000 0,0906654 0,12415535 ! protein ubiquitination GO:0016567 217 97 1,000 0,09226719 0,12627693 ! regulation of protein localization GO:0032880 176 97 1,000 0,09226719 0,12620514 ! response to virus GO:0009615 160 98 1,000 0,09387725 0,12833447 ! protein secretion GO:0009306 39 19 0,000 0,09513567 0,12998094 ! positive regulation of translation GO:0045727 30 19 0,000 0,09513567 0,12990717 ! negative regulation of defense response GO:0031348 25 19 0,000 0,09513567 0,12983348 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,09513567 0,12975988 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,09513567 0,12968636 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,09513567 0,12961293 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,09513567 0,12953958 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,09513567 0,12946631 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,09513567 0,12939312 ! bile acid metabolic process GO:0008206 29 19 0,000 0,09513567 0,12932002 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,09513567 0,129247 ! cerebral cortex development GO:0021987 36 19 0,000 0,09513567 0,12917406 ! pigmentation during development GO:0048066 41 19 0,000 0,09513567 0,1291012 ! response to vitamin A GO:0033189 27 19 0,000 0,09513567 0,12902843 ! heme metabolic process GO:0042168 36 19 0,000 0,09513567 0,12895574 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,09513567 0,12888313 ! peptide cross-linking GO:0018149 37 19 0,000 0,09513567 0,1288106 ! protein export from nucleus GO:0006611 36 19 0,000 0,09513567 0,12873815 ! heart process GO:0003015 30 19 0,000 0,09513567 0,12866579 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,09513567 0,1285935 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,09513567 0,1285213 ! visual learning GO:0008542 36 19 0,000 0,09513567 0,12844918 ! cellular pigmentation GO:0033059 36 19 0,000 0,09513567 0,12837714 ! G1 phase GO:0051318 40 19 0,000 0,09513567 0,12830518 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,09513567 0,1282333 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,09513567 0,1281615 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,09513567 0,12808978 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,09513567 0,12801814 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,09513567 0,12794658 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,09513567 0,1278751 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,09513567 0,1278037 ! cilium assembly GO:0042384 37 19 0,000 0,09513567 0,12773238 ! peptide hormone secretion GO:0030072 31 19 0,000 0,09513567 0,12766114 ! Golgi vesicle transport GO:0048193 207 99 1,000 0,09549546 0,12807251 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,09988578 0,13388589 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,09988578 0,13381135 ! positive regulation of ossification GO:0045778 47 20 0,000 0,09988578 0,13373688 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,09988578 0,1336625 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,09988578 0,1335882 ! cAMP metabolic process GO:0046058 36 20 0,000 0,09988578 0,13351399 ! response to vitamin GO:0033273 31 20 0,000 0,09988578 0,13343985 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,09988578 0,1333658 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,09988578 0,13329183 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,09988578 0,13321795 ! retinoid metabolic process GO:0001523 32 20 0,000 0,09988578 0,13314414 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,09988578 0,13307042 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,09988578 0,13299678 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,09988578 0,13292322 GO:0032392|DNA geometric change, ! D-ribose metabolic process GO:0006014 29 20 0,000 0,09988578 0,13284974 ! body fluid secretion GO:0007589 31 20 0,000 0,09988578 0,13277634 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,09988578 0,13270302 ! peptide secretion GO:0002790 35 20 0,000 0,09988578 0,13262979 ! stem cell differentiation GO:0048863 53 20 0,000 0,09988578 0,13255663 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,09988578 0,13248356 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,09988578 0,13241057 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,09988578 0,13233765 ! sensory perception of pain GO:0019233 30 20 0,000 0,09988578 0,13226482 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,09988578 0,13219207 ! diencephalon development GO:0021536 34 20 0,000 0,09988578 0,13211939 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,09988578 0,1320468 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,09988578 0,13197429 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,09988578 0,13190185 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,09988578 0,1318295 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,09988578 0,13175722 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,09988578 0,13168503 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,09988578 0,13161291 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,09988578 0,13154087 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,09988578 0,13146892 ! actin filament-based movement GO:0030048 43 20 0,000 0,09988578 0,13139704 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,09988578 0,13132523 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,09988578 0,13125351 ! negative regulation of translation GO:0017148 29 20 0,000 0,09988578 0,13118187 ! regulation of cell killing GO:0031341 42 21 0,000 0,1046111 0,13731277 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,1046111 0,1372379 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,1046111 0,13716311 ! hormone secretion GO:0046879 38 21 0,000 0,1046111 0,1370884 ! glycerol metabolic process GO:0006071 34 21 0,000 0,1046111 0,13701377 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,1046111 0,13693923 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,1046111 0,13686477 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,1046111 0,13679038 ! ovarian follicle development GO:0001541 35 21 0,000 0,1046111 0,13671608 ! smooth muscle contraction GO:0006939 46 21 0,000 0,1046111 0,13664186 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,1046111 0,13656772 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,1046111 0,13649366 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,1046111 0,13641968 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,1046111 0,13634578 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,1046111 0,13627196 ! cytolysis GO:0019835 24 21 0,000 0,1046111 0,13619822 ! vasodilation GO:0042311 39 21 0,000 0,1046111 0,13612456 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,1046111 0,13605098 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,1046111 0,13597747 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,1046111 0,13590405 ! oogenesis GO:0048477 36 21 0,000 0,1046111 0,13583071 ! collagen fibril organization GO:0030199 59 21 0,000 0,1046111 0,13575745 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,1046111 0,13568426 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,1046111 0,13561116 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,1046111 0,13553813 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,1046111 0,13546518 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,1046111 0,13539231 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,1046111 0,13531952 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,1046111 0,13524681 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,1046111 0,13517417 ! collagen catabolic process GO:0030574 28 21 0,000 0,1046111 0,13510161 ! sperm-egg recognition GO:0035036 21 21 0,000 0,1046111 0,13502913 ! gut development GO:0048565 39 21 0,000 0,1046111 0,13495673 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,10931177 0,1409454 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,10931177 0,14086991 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,10931177 0,1407945 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,10931177 0,14071917 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,10931177 0,14064392 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,10931177 0,14056875 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,10931177 0,14049366 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,10931177 0,14041865 ! regeneration GO:0031099 41 22 0,000 0,10931177 0,14034372 ! keratinization GO:0031424 28 22 0,000 0,10931177 0,14026887 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,10931177 0,1401941 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,10931177 0,1401194 ! sensory perception of taste GO:0050909 28 22 0,000 0,10931177 0,14004479 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,10931177 0,13997026 ! vacuolar transport GO:0007034 36 22 0,000 0,10931177 0,13989581 ! lysosome organization GO:0007040 41 22 0,000 0,10931177 0,13982144 ! central nervous system neuron development GO:0021954 46 22 0,000 0,10931177 0,13974714 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,10931177 0,13967293 ! fucose metabolic process GO:0006004 39 22 0,000 0,10931177 0,13959879 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,10931177 0,13952473 ! ureteric bud development GO:0001657 43 22 0,000 0,10931177 0,13945075 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,10931177 0,13937685 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,10931177 0,13930303 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,10931177 0,13922929 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,10931177 0,13915562 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,10931177 0,13908203 ! sarcomere organization GO:0045214 30 22 0,000 0,10931177 0,13900852 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,10931177 0,13893509 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,10931177 0,13886173 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,10931177 0,13878846 ! protein stabilization GO:0050821 39 22 0,000 0,10931177 0,13871525 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,11398792 0,14457298 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,11398792 0,14449681 ! gluconeogenesis GO:0006094 33 23 0,000 0,11398792 0,14442072 ! viral genome replication GO:0019079 41 23 0,000 0,11398792 0,14434471 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,11398792 0,14426877 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,11398792 0,14419292 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,11398792 0,14411715 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,11398792 0,14404146 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,11398792 0,14396585 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,11398792 0,14389032 ! visual behavior GO:0007632 42 23 0,000 0,11398792 0,14381486 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,11398792 0,14373949 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,11398792 0,14366419 ! response to ethanol GO:0045471 46 23 0,000 0,11398792 0,14358897 ! peroxisome organization GO:0007031 37 23 0,000 0,11398792 0,14351384 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,11398792 0,14343878 ! vesicle targeting GO:0006903 43 23 0,000 0,11398792 0,1433638 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,11398792 0,14328889 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,11398792 0,14321407 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,11398792 0,14313932 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,11398792 0,14306465 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,11398792 0,14299006 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,11398792 0,14291555 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,11398792 0,14284111 ! fatty acid transport GO:0015908 44 23 0,000 0,11398792 0,14276676 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,11398792 0,14269248 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,11398792 0,14261827 ! hormone transport GO:0009914 40 23 0,000 0,11398792 0,14254415 ! cell-cell recognition GO:0009988 25 23 0,000 0,11398792 0,1424701 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,11398792 0,14239613 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,11398792 0,14232223 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,11398792 0,14224841 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,11398792 0,14217467 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,11398792 0,14210101 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,11863968 0,14782344 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,11863968 0,14774693 ! vesicle docking GO:0048278 47 24 0,000 0,11863968 0,14767049 ! spinal cord development GO:0021510 47 24 0,000 0,11863968 0,14759414 ! vacuole organization GO:0007033 43 24 0,000 0,11863968 0,14751786 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,11863968 0,14744166 ! digestive system process GO:0022600 39 24 0,000 0,11863968 0,14736555 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,11863968 0,14728951 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,11863968 0,14721354 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,11863968 0,14713766 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,11863968 0,14706186 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,11863968 0,14698613 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,11863968 0,14691048 ! membrane depolarization GO:0051899 39 24 0,000 0,11863968 0,14683491 ! pallium development GO:0021543 49 24 0,000 0,11863968 0,14675942 ! pentose metabolic process GO:0019321 35 24 0,000 0,11863968 0,146684 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,11863968 0,14660866 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,11863968 0,1465334 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,11863968 0,14645822 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,11863968 0,14638311 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,11863968 0,14630808 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,11863968 0,14623313 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,11863968 0,14615825 ! regulation of amine transport GO:0051952 40 24 0,000 0,11863968 0,14608345 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,12326716 0,15170373 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,12326716 0,15162617 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,12326716 0,15154869 ! phototransduction GO:0007602 33 25 0,000 0,12326716 0,15147129 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,12326716 0,15139397 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,12326716 0,15131673 ! sperm motility GO:0030317 31 25 0,000 0,12326716 0,15123957 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,12326716 0,15116248 ! receptor metabolic process GO:0043112 46 25 0,000 0,12326716 0,15108548 ! chromosome condensation GO:0030261 45 25 0,000 0,12326716 0,15100855 ! osteoblast differentiation GO:0001649 60 25 0,000 0,12326716 0,1509317 ! neural crest cell development GO:0014032 54 25 0,000 0,12326716 0,15085493 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,12326716 0,15077824 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,12326716 0,15070162 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,12326716 0,15062509 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,12326716 0,15054863 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,12326716 0,15047224 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,12326716 0,15039594 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,12326716 0,15031971 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,12326716 0,15024356 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,12326716 0,15016749 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,12326716 0,15009149 ! telomere organization GO:0032200 43 25 0,000 0,12326716 0,15001558 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,12326716 0,14993973 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,12326716 0,14986397 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,12787051 0,15538204 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,12787051 0,1553036 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,12787051 0,15522525 ! initiation of viral infection GO:0019059 57 26 0,000 0,12787051 0,15514697 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,12787051 0,15506877 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,12787051 0,15499065 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,12787051 0,15491261 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,12787051 0,15483464 ! molting cycle process GO:0022404 50 26 0,000 0,12787051 0,15475676 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,12787051 0,15467895 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,12787051 0,15460122 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,12787051 0,15452357 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,12787051 0,154446 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,12787051 0,15436851 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,12787051 0,15429109 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,12787051 0,15421375 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,12787051 0,15413649 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,12787051 0,15405931 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,12787051 0,1539822 ! blastocyst development GO:0001824 49 26 0,000 0,12787051 0,15390517 ! leukocyte proliferation GO:0070661 52 26 0,000 0,12787051 0,15382822 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,12787051 0,15375134 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,12787051 0,15367454 ! neuron fate commitment GO:0048663 48 27 0,000 0,13244983 0,1590985 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,13244983 0,15901911 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,13244983 0,1589398 ! iron ion transport GO:0006826 59 27 0,000 0,13244983 0,15886056 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,13244983 0,15878141 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,13244983 0,15870234 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,13244983 0,15862334 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,13244983 0,15854442 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,13244983 0,15846558 ! autophagy GO:0006914 41 27 0,000 0,13244983 0,15838682 ! male gonad development GO:0008584 44 27 0,000 0,13244983 0,15830814 ! response to toxin GO:0009636 47 27 0,000 0,13244983 0,15822954 ! primary neural tube formation GO:0014020 51 27 0,000 0,13244983 0,15815101 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,13244983 0,15807257 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,13244983 0,15799419 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,13244983 0,1579159 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,13244983 0,15783769 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,13244983 0,15775955 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,13700526 0,16310473 ! circadian rhythm GO:0007623 50 28 0,000 0,13700526 0,16302406 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,13700526 0,16294348 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,13700526 0,16286297 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,13700526 0,16278255 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,13700526 0,1627022 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,13700526 0,16262193 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,13700526 0,16254175 ! synaptogenesis GO:0007416 42 28 0,000 0,13700526 0,16246164 ! lipid oxidation GO:0034440 43 28 0,000 0,13700526 0,16238161 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,13700526 0,16230165 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,13700526 0,16222178 ! translational initiation GO:0006413 65 29 0,000 0,14153692 0,16750508 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,14153692 0,16742273 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,14153692 0,16734046 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,14153692 0,16725827 ! catechol metabolic process GO:0009712 54 29 0,000 0,14153692 0,16717616 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,14153692 0,16709413 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,14153692 0,16701218 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,14153692 0,16693031 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,14153692 0,16684852 ! cell fate determination GO:0001709 60 29 0,000 0,14153692 0,16676682 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,14153692 0,16668519 ! detection of light stimulus GO:0009583 38 29 0,000 0,14153692 0,16660364 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,14153692 0,16652217 ! tissue homeostasis GO:0001894 48 29 0,000 0,14153692 0,16644078 GO:0048871|multicellular organismal homeostasis, ! phenol metabolic process GO:0018958 55 30 0,000 0,14604494 0,1716581 ! zinc ion transport GO:0006829 45 30 0,000 0,14604494 0,17157428 ! membrane docking GO:0022406 61 30 0,000 0,14604494 0,17149054 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,14604494 0,17140689 ! regulation of innate immune response GO:0045088 51 30 0,000 0,14604494 0,17132332 ! acute-phase response GO:0006953 49 30 0,000 0,14604494 0,17123983 ! myofibril assembly GO:0030239 47 30 0,000 0,14604494 0,17115642 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,14604494 0,17107309 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,14604494 0,17098984 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,14604494 0,17090667 ! phospholipid transport GO:0015914 51 30 0,000 0,14604494 0,17082359 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,14604494 0,17074058 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,14604494 0,17065766 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,14604494 0,17057482 ! eye morphogenesis GO:0048592 60 30 0,000 0,14604494 0,17049205 ! response to heat GO:0009408 50 30 0,000 0,14604494 0,17040937 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,15052943 0,17555686 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,15052943 0,17547181 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,15052943 0,17538683 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,15052943 0,17530194 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,15052943 0,17521713 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,15052943 0,1751324 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,15052943 0,17504776 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,15052943 0,17496319 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,15052943 0,17487871 ! ovulation cycle process GO:0022602 49 31 0,000 0,15052943 0,17479431 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,15052943 0,17470999 ! peptide transport GO:0015833 55 31 0,000 0,15052943 0,17462575 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,15052943 0,17454159 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,15052943 0,17445752 ! mesoderm formation GO:0001707 69 31 0,000 0,15052943 0,17437352 ! natural killer cell activation GO:0030101 45 31 0,000 0,15052943 0,17428961 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,15052943 0,17420578 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,15052943 0,17412202 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,15052943 0,17403835 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,15052943 0,17395476 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,15052943 0,17387125 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,15499052 0,17893819 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,15499052 0,17885237 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,15499052 0,17876663 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,15499052 0,17868097 ! cholesterol transport GO:0030301 56 32 0,000 0,15499052 0,1785954 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,15499052 0,1785099 ! spliceosome assembly GO:0000245 67 32 0,000 0,15499052 0,17842449 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,15499052 0,17833916 ! metanephros development GO:0001656 74 32 0,000 0,15499052 0,17825392 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,15499052 0,17816875 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,15499052 0,17808366 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,15499052 0,17799866 ! muscle cell development GO:0055001 49 32 0,000 0,15499052 0,17791374 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,15499052 0,17782889 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,15499052 0,17774413 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,15499052 0,17765945 ! ovulation cycle GO:0042698 51 32 0,000 0,15499052 0,17757485 ! hindbrain development GO:0030902 61 32 0,000 0,15499052 0,17749033 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,15499052 0,17740589 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,15499052 0,17732154 ! gene silencing GO:0016458 65 32 0,000 0,15499052 0,17723726 ! post-embryonic development GO:0009791 69 33 0,000 0,15942833 0,18222544 ! protein targeting to membrane GO:0006612 68 33 0,000 0,15942833 0,18213892 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,15942833 0,18205247 ! ceramide metabolic process GO:0006672 64 33 0,000 0,15942833 0,18196611 ! formation of primary germ layer GO:0001704 72 33 0,000 0,15942833 0,18187983 ! cell fate specification GO:0001708 52 33 0,000 0,15942833 0,18179363 ! sterol transport GO:0015918 57 33 0,000 0,15942833 0,18170751 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,15942833 0,18162148 ! adult locomotory behavior GO:0008344 59 33 0,000 0,15942833 0,18153552 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,15942833 0,18144965 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,15942833 0,18136386 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,16384298 0,18629783 ! glial cell differentiation GO:0010001 63 34 0,000 0,16384298 0,18620983 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,16384298 0,18612191 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,16384298 0,18603408 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,16384298 0,18594632 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,16384298 0,18585866 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,16384298 0,18577107 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,16384298 0,18568356 ! mismatch repair GO:0006298 46 34 0,000 0,16384298 0,18559614 ! spermatid development GO:0007286 63 34 0,000 0,16384298 0,1855088 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,16384298 0,18542155 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,16384298 0,18533437 ! placenta development GO:0001890 53 34 0,000 0,16384298 0,18524728 ! regulation of muscle development GO:0048634 70 35 0,000 0,16823459 0,19012326 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,16823459 0,190034 ! negative regulation of secretion GO:0051048 63 35 0,000 0,16823459 0,18994482 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,16823459 0,18985573 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,16823459 0,18976672 ! odontogenesis GO:0042476 66 35 0,000 0,16823459 0,1896778 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,16823459 0,18958896 ! female gonad development GO:0008585 58 35 0,000 0,16823459 0,1895002 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,16823459 0,18941152 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,16823459 0,18932293 ! cytokine production GO:0001816 59 35 0,000 0,16823459 0,18923442 ! neural tube formation GO:0001841 67 35 0,000 0,16823459 0,18914599 ! vesicle localization GO:0051648 64 35 0,000 0,16823459 0,18905765 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,17260328 0,19387651 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,17260328 0,19378604 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,17260328 0,19369566 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,17260328 0,19360536 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,17260328 0,19351514 ! positive regulation of cell development GO:0010720 80 36 0,000 0,17260328 0,19342501 ! regulation of proteolysis GO:0030162 72 36 0,000 0,17260328 0,19333496 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,17260328 0,19324499 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,17260328 0,19315511 ! aerobic respiration GO:0009060 55 36 0,000 0,17260328 0,19306531 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,17260328 0,1929756 ! embryonic organ development GO:0048568 57 36 0,000 0,17260328 0,19288597 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,17260328 0,19279642 ! RNA export from nucleus GO:0006405 56 37 0,000 0,17694917 0,19755903 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,17694917 0,19746739 ! actomyosin structure organization GO:0031032 62 37 0,000 0,17694917 0,19737585 ! organic anion transport GO:0015711 68 37 0,000 0,17694917 0,19728438 ! tissue remodeling GO:0048771 76 37 0,000 0,17694917 0,19719301 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,17694917 0,19710171 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,17694917 0,1970105 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,17694917 0,19691938 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,17694917 0,19682834 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,17694917 0,19673738 ! pigment metabolic process GO:0042440 80 37 0,000 0,17694917 0,19664651 ! spermatid differentiation GO:0048515 66 37 0,000 0,17694917 0,19655572 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,18127237 0,20126504 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,18127237 0,2011722 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,18127237 0,20107945 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,18127237 0,20098679 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,18127237 0,20089421 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,18127237 0,20080172 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,18127237 0,20070931 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,18127237 0,20061699 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,18127237 0,20052475 ! mRNA catabolic process GO:0006402 71 39 0,000 0,18557301 0,20518781 ! organic ether metabolic process GO:0018904 55 39 0,000 0,18557301 0,20509356 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,18557301 0,20499939 ! ion transmembrane transport GO:0034220 66 39 0,000 0,18557301 0,20490531 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,18557301 0,20481132 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,18557301 0,20471741 ! RNA modification GO:0009451 57 39 0,000 0,18557301 0,20462359 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,18557301 0,20452985 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,18985121 0,20914927 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,18985121 0,20905355 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,18985121 0,20895792 ! negative regulation of binding GO:0051100 72 40 0,000 0,18985121 0,20886237 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,18985121 0,20876691 ! mesenchymal cell development GO:0014031 87 40 0,000 0,18985121 0,20867154 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of protein location GO:0045185 91 40 0,000 0,18985121 0,20857626 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,19410707 0,21315454 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,19410707 0,2130573 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,19410707 0,21296015 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,19410707 0,21286308 ! gliogenesis GO:0042063 88 41 0,000 0,19410707 0,21276611 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,19410707 0,21266922 ! female gamete generation GO:0007292 61 41 0,000 0,19410707 0,21257242 ! polyol metabolic process GO:0019751 66 41 0,000 0,19410707 0,21247571 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,19410707 0,21237908 ! regulation of tube size GO:0035150 71 42 0,000 0,19834071 0,21691261 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,19834071 0,21681406 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,19834071 0,2167156 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,19834071 0,21661723 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,19834071 0,21651894 ! neuron migration GO:0001764 79 42 0,000 0,19834071 0,21642075 ! regulation of protein secretion GO:0050708 71 42 0,000 0,19834071 0,21632264 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,19834071 0,21622463 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,20255225 0,22071591 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,20255225 0,22061599 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,20255225 0,22051616 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,20255225 0,22041643 ! neural tube development GO:0021915 77 43 0,000 0,20255225 0,22031678 ! striated muscle contraction GO:0006941 77 43 0,000 0,20255225 0,22021723 ! phagocytosis GO:0006909 90 43 0,000 0,20255225 0,22011776 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,20255225 0,22001839 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,20674181 0,22446787 ! male sex differentiation GO:0046661 76 44 0,000 0,20674181 0,22436662 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,20674181 0,22426546 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,20674181 0,2241644 ! developmental growth GO:0048589 82 44 0,000 0,20674181 0,22406342 ! maintenance of location in cell GO:0051651 97 44 0,000 0,20674181 0,22396254 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,2109095 0,22837455 ! glycolysis GO:0006096 65 45 0,000 0,2109095 0,22827182 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,2109095 0,22816918 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,2109095 0,22806663 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,2109095 0,22796417 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,2109095 0,22786181 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,2109095 0,22775954 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,2109095 0,22765736 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,2109095 0,22755527 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,21505542 0,23192441 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,2191797 0,23626629 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,2191797 0,23616049 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,2191797 0,23605478 ! JNK cascade GO:0007254 91 47 0,000 0,2191797 0,23594916 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,2191797 0,23584363 ! protein homooligomerization GO:0051260 76 47 0,000 0,2191797 0,23573821 ! Notch signaling pathway GO:0007219 96 48 0,000 0,22328245 0,2400436 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,22328245 0,23993639 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,22328245 0,23982928 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,22328245 0,23972226 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,22328245 0,23961533 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,22736378 0,24388642 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,22736378 0,24377774 ! regulation of ion transport GO:0043269 77 49 0,000 0,22736378 0,24366915 ! response to temperature stimulus GO:0009266 76 49 0,000 0,22736378 0,24356066 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,22736378 0,24345227 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,22736378 0,24334397 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,22736378 0,24323577 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,23142379 0,24746917 ! neuromuscular process GO:0050905 99 50 0,000 0,23142379 0,24735924 ! regulation of ossification GO:0030278 117 50 0,000 0,23142379 0,2472494 ! inner ear development GO:0048839 79 50 0,000 0,23142379 0,24713965 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,23142379 0,24703001 ! viral infectious cycle GO:0019058 99 51 0,000 0,23546261 0,25122973 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,23546261 0,25111836 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,23546261 0,2510071 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,23546261 0,25089594 ! excretion GO:0007588 83 51 0,000 0,23546261 0,25078487 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,23546261 0,25067391 ! chromatin remodeling GO:0006338 109 51 0,000 0,23546261 0,25056304 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,23546261 0,25045227 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,23546261 0,2503416 ! vesicle organization GO:0016050 107 51 0,000 0,23546261 0,25023102 ! regulation of cell shape GO:0008360 125 51 0,000 0,23546261 0,25012054 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,23546261 0,25001016 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,23948033 0,25416395 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,24347707 0,25829182 ! RNA catabolic process GO:0006401 93 53 0,000 0,24347707 0,25817798 ! regulation of translational initiation GO:0006446 82 53 0,000 0,24347707 0,25806425 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,24347707 0,25795061 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,24347707 0,25783708 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,24347707 0,25772364 ! cell maturation GO:0048469 100 53 0,000 0,24347707 0,25761031 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,24347707 0,25749707 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,24745295 0,2615869 ! cell recognition GO:0008037 85 54 0,000 0,24745295 0,26147202 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,24745295 0,26135724 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,24745295 0,26124256 ! chloride transport GO:0006821 90 55 0,000 0,25140806 0,26530166 ! glucose catabolic process GO:0006007 82 55 0,000 0,25140806 0,26518535 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,25140806 0,26506914 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,25140806 0,26495304 ! gastrulation GO:0007369 112 55 0,000 0,25140806 0,26483703 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,25140806 0,26472113 ! RNA elongation GO:0006354 79 55 0,000 0,25140806 0,26460533 ! nuclear export GO:0051168 97 55 0,000 0,25140806 0,26448963 ! regulation of actin filament length GO:0030832 105 56 0,000 0,25534251 0,2685114 ! sensory perception of smell GO:0007608 80 56 0,000 0,25534251 0,26839409 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,25534251 0,26827689 ! proton transport GO:0015992 94 56 0,000 0,25534251 0,26815979 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,25925641 0,27215137 ! maintenance of location GO:0051235 118 57 0,000 0,25925641 0,27203268 ! hydrogen transport GO:0006818 97 58 0,000 0,26314988 0,27599765 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,26314988 0,27587739 ! regulation of endocytosis GO:0030100 91 58 0,000 0,26314988 0,27575723 ! adult behavior GO:0030534 99 58 0,000 0,26314988 0,27563718 ! positive regulation of secretion GO:0051047 95 59 0,000 0,267023 0,27957239 ! regulation of cellular component size GO:0032535 109 59 0,000 0,267023 0,27945078 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,267023 0,27932928 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,267023 0,27920789 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,2708759 0,28311356 ! camera-type eye development GO:0043010 116 60 0,000 0,2708759 0,28299063 ! kidney development GO:0001822 122 60 0,000 0,2708759 0,2828678 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,27470867 0,2867458 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,27470867 0,28662145 ! mesoderm development GO:0007498 119 61 0,000 0,27470867 0,28649721 ! tRNA processing GO:0008033 89 61 0,000 0,27470867 0,28637308 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,27470867 0,28624905 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,27852142 0,29009634 ! gonad development GO:0008406 98 62 0,000 0,27852142 0,28997081 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,28231425 0,29379243 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,28231425 0,29366541 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,28608727 0,29746153 ! cell redox homeostasis GO:0045454 102 64 0,000 0,28608727 0,29733304 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,28608727 0,29720466 GO:0048609|reproductive process in a multicellular organism, ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,28984058 0,30097387 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,28984058 0,30084402 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,28984058 0,30071429 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,28984058 0,30058467 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,29357429 0,30432561 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,29357429 0,30419454 ! extracellular matrix organization GO:0030198 133 66 0,000 0,29357429 0,30406359 ! secondary metabolic process GO:0019748 116 66 0,000 0,29357429 0,30393276 ! developmental maturation GO:0021700 116 66 0,000 0,29357429 0,30380203 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,29728848 0,30751336 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,29728848 0,30738121 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,29728848 0,30724918 ! hexose catabolic process GO:0019320 104 67 0,000 0,29728848 0,30711725 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,29728848 0,30698544 ! amino acid transport GO:0006865 125 68 0,000 0,30098327 0,31066742 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,30098327 0,3105342 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,30465875 0,31419158 ! urogenital system development GO:0001655 137 69 0,000 0,30465875 0,31405697 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,30465875 0,31392247 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,30465875 0,31378808 ! antigen processing and presentation GO:0019882 104 69 0,000 0,30465875 0,31365381 ! appendage morphogenesis GO:0035107 135 70 0,000 0,30831503 0,31728228 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,31195221 0,32088799 ! reproductive structure development GO:0048608 113 71 0,000 0,31195221 0,32075086 ! appendage development GO:0048736 136 71 0,000 0,31195221 0,32061385 GO:0060173|limb development, ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,31195221 0,32047695 ! regulation of immune effector process GO:0002697 137 71 0,000 0,31195221 0,32034017 ! regulation of blood pressure GO:0008217 125 73 0,000 0,31916964 0,32761185 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,31916964 0,32747214 ! transition metal ion transport GO:0000041 126 74 0,000 0,3227501 0,33100458 ! neurotransmitter transport GO:0006836 123 74 0,000 0,3227501 0,33086355 ! exocytosis GO:0006887 133 74 0,000 0,3227501 0,33072263 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,3227501 0,33058184 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,32631184 0,33408779 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,32631184 0,33394568 ! rhythmic process GO:0048511 128 75 0,000 0,32631184 0,3338037 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,32985498 0,33728477 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,32985498 0,33714149 ! defense response to bacterium GO:0042742 89 76 0,000 0,32985498 0,33699833 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,32985498 0,33685529 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,32985498 0,33671238 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,33337959 0,34016594 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,33337959 0,34002174 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,33688578 0,3434522 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,33688578 0,34330673 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,34037365 0,34671422 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,34037365 0,3465675 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,34384329 0,34995218 ! muscle cell differentiation GO:0042692 159 80 0,000 0,34384329 0,34980421 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,34384329 0,34965636 ! inorganic anion transport GO:0015698 138 80 0,000 0,34384329 0,34950864 ! digestion GO:0007586 112 81 0,000 0,34729479 0,35286793 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,34729479 0,35271898 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,35072825 0,35605577 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,35072825 0,35590559 ! response to nutrient GO:0007584 125 82 0,000 0,35072825 0,35575555 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,35072825 0,35560563 ! regulation of lyase activity GO:0051339 160 83 0,000 0,35414376 0,35891739 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,35754142 0,36220828 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,35754142 0,36205583 ! amine biosynthetic process GO:0009309 138 86 0,000 0,36428355 0,3687279 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,36428355 0,36857284 ! tube morphogenesis GO:0035239 176 86 0,000 0,36428355 0,36841791 ! alcohol catabolic process GO:0046164 130 86 0,000 0,36428355 0,36826311 ! amine transport GO:0015837 155 86 0,000 0,36428355 0,36810845 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,3676282 0,37133226 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,3676282 0,37117643 ! cellular respiration GO:0045333 135 88 0,000 0,37095536 0,37437861 ! regulation of neurological system process GO:0031644 148 88 0,000 0,37095536 0,37422163 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,37095536 0,37406479 ! cellular defense response GO:0006968 114 89 0,000 0,37426513 0,3772442 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,37426513 0,37708622 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,37755759 0,38024427 ! sex differentiation GO:0007548 145 90 0,000 0,37755759 0,38008518 ! sterol metabolic process GO:0016125 152 91 0,000 0,38083284 0,38322201 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,38083284 0,3830618 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,38409097 0,38617754 ! vitamin metabolic process GO:0006766 139 92 0,000 0,38409097 0,38601623 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,38733205 0,38911103 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,38733205 0,38894863 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,39055619 0,39202261 ! female pregnancy GO:0007565 164 94 0,000 0,39055619 0,39185913 ! forebrain development GO:0030900 188 95 0,000 0,39376347 0,39491242 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,39376347 0,39474788 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,39695398 0,39778062 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,4001278 0,40079412 ! hormone metabolic process GO:0042445 157 97 0,000 0,4001278 0,40062733 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,40328502 0,40362053 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,40328502 0,4034527 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,40642573 0,40642573