pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6467-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! ER overload response GO:0006983 6 6 2,000 4,179E-07 7,702E-04 ! angiogenesis GO:0001525 65 64 4,000 8,276E-07 7,626E-04 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 2,000 1,746E-06 1,072E-03 ! blood vessel morphogenesis GO:0048514 84 83 4,000 3,044E-06 1,402E-03 ! negative regulation of cell cycle GO:0045786 92 91 4,000 4,804E-06 1,771E-03 ! blood vessel development GO:0001568 95 94 4,000 5,64E-06 1,732E-03 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 2,000 5,899E-06 1,553E-03 ! response to endoplasmic reticulum stress GO:0034976 13 13 2,000 5,899E-06 1,359E-03 ! vasculature development GO:0001944 97 96 4,000 6,257E-06 1,281E-03 ! ER-nuclear signaling pathway GO:0006984 15 15 2,000 9,35E-06 1,723E-03 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 2,000 1,392E-05 2,333E-03 ! regulation of cell migration GO:0030334 71 71 3,000 4,454E-05 6,84E-03 ! regulation of intracellular protein transport GO:0033157 25 25 2,000 4,64E-05 6,578E-03 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 2,000 5,878E-05 7,739E-03 ! regulation of locomotion GO:0040012 79 79 3,000 6,785E-05 8,337E-03 ! regulation of cell motion GO:0051270 79 79 3,000 6,785E-05 7,816E-03 ! response to UV GO:0009411 29 29 2,000 7,316E-05 7,932E-03 ! prostate gland development GO:0030850 5 5 1,000 7,987E-05 8,178E-03 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 7,987E-05 7,748E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 7,987E-05 7,36E-03 ! mRNA stabilization GO:0048255 5 5 1,000 7,987E-05 7,01E-03 GO:0043489|RNA stabilization, ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 7,987E-05 6,691E-03 ! negative regulation of focal adhesion formation GO:0051895 6 5 1,000 7,987E-05 6,4E-03 ! T cell lineage commitment GO:0002360 5 5 1,000 7,987E-05 6,134E-03 ! aging GO:0007568 32 31 2,000 8,967E-05 6,61E-03 ! regulation of intracellular transport GO:0032386 31 31 2,000 8,967E-05 6,356E-03 ! cartilage condensation GO:0001502 7 6 1,000 1,196E-04 8,164E-03 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 1,196E-04 7,872E-03 GO:0050927|positive regulation of positive chemotaxis, ! nerve growth factor receptor signaling pathway GO:0048011 6 6 1,000 1,196E-04 7,601E-03 ! regulation of vascular permeability GO:0043114 6 6 1,000 1,196E-04 7,347E-03 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 1,196E-04 7,11E-03 ! regulation of bone resorption GO:0045124 6 6 1,000 1,196E-04 6,888E-03 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 1,196E-04 6,679E-03 ! regulation of focal adhesion formation GO:0051893 7 6 1,000 1,196E-04 6,483E-03 ! nitric oxide metabolic process GO:0046209 6 6 1,000 1,196E-04 6,298E-03 GO:0006809|nitric oxide biosynthetic process, ! localization within membrane GO:0051668 6 6 1,000 1,196E-04 6,123E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 1,296E-04 6,455E-03 ! positive regulation of cell migration GO:0030335 36 36 2,000 1,411E-04 6,844E-03 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 1,000 1,671E-04 7,899E-03 ! regulation of defense response to virus GO:0050688 7 7 1,000 1,671E-04 7,701E-03 ! regulation of mRNA processing GO:0050684 7 7 1,000 1,671E-04 7,513E-03 ! cardiac muscle tissue development GO:0048738 7 7 1,000 1,671E-04 7,335E-03 ! response to X-ray GO:0010165 7 7 1,000 1,671E-04 7,164E-03 ! regulation of intracellular pH GO:0051453 7 7 1,000 1,671E-04 7,001E-03 ! response to gamma radiation GO:0010332 8 7 1,000 1,671E-04 6,846E-03 ! synaptic transmission, cholinergic GO:0007271 7 7 1,000 1,671E-04 6,697E-03 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 1,000 1,671E-04 6,554E-03 GO:0001953|negative regulation of cell-matrix adhesion, ! regulation of mRNA stability GO:0043488 7 7 1,000 1,671E-04 6,418E-03 ! positive regulation of cell motion GO:0051272 39 39 2,000 1,796E-04 6,756E-03 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 2,225E-04 8,2E-03 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 2,225E-04 8,04E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 2,225E-04 7,885E-03 ! peptidyl-serine modification GO:0018209 8 8 1,000 2,225E-04 7,736E-03 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 2,225E-04 7,593E-03 ! regulation of RNA stability GO:0043487 8 8 1,000 2,225E-04 7,455E-03 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 2,225E-04 7,322E-03 ! regulation of multi-organism process GO:0043900 8 8 1,000 2,225E-04 7,193E-03 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 2,855E-04 9,073E-03 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 2,855E-04 8,919E-03 ! substrate-bound cell migration GO:0006929 9 9 1,000 2,855E-04 8,771E-03 ! regulation of cellular pH GO:0030641 9 9 1,000 2,855E-04 8,627E-03 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 2,855E-04 8,488E-03 ! regulation of leukocyte migration GO:0002685 9 9 1,000 2,855E-04 8,353E-03 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 2,855E-04 8,223E-03 ! ossification GO:0001503 50 49 2,000 3,555E-04 0,01007884 GO:0060348|bone development, ! cell cycle arrest GO:0007050 49 49 2,000 3,555E-04 9,926E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 3,563E-04 9,801E-03 ! inositol metabolic process GO:0006020 10 10 1,000 3,563E-04 9,657E-03 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 3,563E-04 9,517E-03 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 3,563E-04 9,381E-03 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 3,563E-04 9,249E-03 ! regulation of neurogenesis GO:0050767 51 50 2,000 3,775E-04 9,662E-03 ! response to light stimulus GO:0009416 53 52 2,000 4,24E-04 0,01070515 ! microtubule-based transport GO:0010970 11 11 1,000 4,347E-04 0,01082689 ! endothelial cell migration GO:0043542 11 11 1,000 4,347E-04 0,01068253 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 4,347E-04 0,01054197 GO:0032388|positive regulation of intracellular transport, ! cellular response to starvation GO:0009267 11 11 1,000 4,347E-04 0,01040507 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 4,347E-04 0,01027167 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 4,347E-04 0,01014165 ! G1/S transition checkpoint GO:0031575 12 11 1,000 4,347E-04 0,01001488 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 4,347E-04 9,891E-03 ! regulation of protein transport GO:0051223 53 53 2,000 4,486E-04 0,01008329 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 5,208E-04 0,01156328 ! collagen metabolic process GO:0032963 12 12 1,000 5,208E-04 0,01142562 ! xenobiotic metabolic process GO:0006805 12 12 1,000 5,208E-04 0,0112912 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 1,000 5,208E-04 0,01115991 ! regulation of response to biotic stimulus GO:0002831 12 12 1,000 5,208E-04 0,01103164 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 5,208E-04 0,01090628 ! regulation of nervous system development GO:0051960 57 56 2,000 5,279E-04 0,01093212 ! regulation of protein localization GO:0032880 58 57 2,000 5,562E-04 0,0113901 ! vasculogenesis GO:0001570 13 13 1,000 6,144E-04 0,01244259 ! mitochondrial membrane organization GO:0007006 13 13 1,000 6,144E-04 0,01230735 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 6,144E-04 0,01217501 ! negative regulation of DNA replication GO:0008156 13 13 1,000 6,144E-04 0,01204549 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 1,000 6,144E-04 0,01191869 ! cell aging GO:0007569 13 13 1,000 6,144E-04 0,01179454 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 6,144E-04 0,01167295 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 6,144E-04 0,01155384 ! negative regulation of protein kinase cascade GO:0010741 13 13 1,000 6,144E-04 0,01143713 ! positive regulation of neurogenesis GO:0050769 13 13 1,000 6,144E-04 0,01132276 ! positive regulation of locomotion GO:0040017 13 13 1,000 6,144E-04 0,01121065 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! negative regulation of intracellular transport GO:0032387 13 13 1,000 6,144E-04 0,01110074 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 6,144E-04 0,01099297 GO:0001952|regulation of cell-matrix adhesion, ! tissue homeostasis GO:0001894 13 13 1,000 6,144E-04 0,01088727 GO:0048871|multicellular organismal homeostasis, ! protein tetramerization GO:0051262 13 13 1,000 6,144E-04 0,01078358 ! regulation of cell development GO:0060284 60 59 2,000 6,157E-04 0,0107049 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 1,000 7,155E-04 0,01232417 ! regulation of behavior GO:0050795 14 14 1,000 7,155E-04 0,01221006 ! base-excision repair GO:0006284 14 14 1,000 7,155E-04 0,01209804 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 8,242E-04 0,01380828 ! response to starvation GO:0042594 15 15 1,000 8,242E-04 0,01368388 ! response to ionizing radiation GO:0010212 16 15 1,000 8,242E-04 0,0135617 ! response to radiation GO:0009314 70 68 2,000 9,334E-04 0,01522418 ! regulation of cell size GO:0008361 68 68 2,000 9,334E-04 0,01509064 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 9,402E-04 0,01506846 ! positive regulation of cell development GO:0010720 16 16 1,000 9,402E-04 0,01493856 ! cellular response to nutrient levels GO:0031669 16 16 1,000 9,402E-04 0,01481088 ! polyol metabolic process GO:0019751 16 16 1,000 9,402E-04 0,01468537 ! positive regulation of catabolic process GO:0009896 16 16 1,000 9,402E-04 0,01456196 ! response to xenobiotic stimulus GO:0009410 16 16 1,000 9,402E-04 0,01444061 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 1,064E-03 0,0162025 ! tissue remodeling GO:0048771 17 17 1,000 1,064E-03 0,01606969 ! response to toxin GO:0009636 18 17 1,000 1,064E-03 0,01593904 ! negative regulation of cell development GO:0010721 18 17 1,000 1,064E-03 0,0158105 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 1,064E-03 0,01568402 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 1,103E-03 0,01612804 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 1,195E-03 0,0173364 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 1,195E-03 0,01720096 ! B cell differentiation GO:0030183 18 18 1,000 1,195E-03 0,01706762 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 1,195E-03 0,01693633 ! DNA damage checkpoint GO:0000077 19 19 1,000 1,333E-03 0,01875163 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 1,333E-03 0,01860957 ! regulation of pH GO:0006885 19 19 1,000 1,333E-03 0,01846965 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 1,333E-03 0,01833182 ! multicellular organismal metabolic process GO:0044236 19 19 1,000 1,333E-03 0,01819603 ! regulation of protein stability GO:0031647 19 19 1,000 1,333E-03 0,01806223 ! regulation of cell shape GO:0008360 21 19 1,000 1,333E-03 0,01793039 ! negative regulation of cell adhesion GO:0007162 21 20 1,000 1,478E-03 0,01974385 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 1,000 1,478E-03 0,01960181 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 1,478E-03 0,01946179 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 1,631E-03 0,02132066 ! morphogenesis of embryonic epithelium GO:0016331 22 21 1,000 1,631E-03 0,02117051 ! DNA integrity checkpoint GO:0031570 21 21 1,000 1,631E-03 0,02102247 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 1,631E-03 0,02087648 ! negative regulation of protein transport GO:0051224 21 21 1,000 1,631E-03 0,0207325 ! regulation of cellular localization GO:0060341 86 85 2,000 1,783E-03 0,02250186 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 1,958E-03 0,02455219 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 1,958E-03 0,02438629 ! calcium-mediated signaling GO:0019722 23 23 1,000 1,958E-03 0,02422263 ! mitochondrial transport GO:0006839 24 24 1,000 2,133E-03 0,02620283 ! T cell differentiation GO:0030217 24 24 1,000 2,133E-03 0,0260293 ! glucan metabolic process GO:0044042 25 24 1,000 2,133E-03 0,02585806 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of gene-specific transcription GO:0032583 25 25 1,000 2,314E-03 0,02787428 ! JAK-STAT cascade GO:0007259 26 25 1,000 2,314E-03 0,02769328 ! negative regulation of cell migration GO:0030336 26 26 1,000 2,503E-03 0,02975563 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 2,503E-03 0,02956489 ! double-strand break repair GO:0006302 27 26 1,000 2,503E-03 0,02937657 ! regulation of cell growth GO:0001558 97 96 2,000 2,527E-03 0,02947165 ! posttranscriptional regulation of gene expression GO:0010608 98 98 2,000 2,68E-03 0,03105995 ! energy reserve metabolic process GO:0006112 28 27 1,000 2,698E-03 0,03107765 ! activation of caspase activity GO:0006919 27 27 1,000 2,698E-03 0,03088463 ! cell growth GO:0016049 27 27 1,000 2,698E-03 0,03069398 ! protein amino acid autophosphorylation GO:0046777 28 28 1,000 2,9E-03 0,03279511 ! cartilage development GO:0051216 29 28 1,000 2,9E-03 0,03259514 ! positive regulation of cell cycle GO:0045787 29 29 1,000 3,11E-03 0,03473688 ! phosphoinositide metabolic process GO:0030384 29 29 1,000 3,11E-03 0,03452762 ! regulation of epithelial cell proliferation GO:0050678 29 29 1,000 3,11E-03 0,03432087 ! positive regulation of protein transport GO:0051222 29 29 1,000 3,11E-03 0,03411657 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 3,326E-03 0,03627397 GO:0043280|positive regulation of caspase activity, ! activation of phospholipase C activity GO:0007202 30 30 1,000 3,326E-03 0,0360606 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 3,326E-03 0,03584972 ! skeletal system morphogenesis GO:0048705 31 30 1,000 3,326E-03 0,03564129 ! vascular process in circulatory system GO:0003018 31 30 1,000 3,326E-03 0,03543527 ! B cell activation GO:0042113 31 31 1,000 3,549E-03 0,03759588 ! regulation of DNA replication GO:0006275 32 31 1,000 3,549E-03 0,03738105 ! negative regulation of cell motion GO:0051271 31 31 1,000 3,549E-03 0,03716866 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 3,549E-03 0,03695867 ! extracellular matrix organization GO:0030198 31 31 1,000 3,549E-03 0,03675103 ! negative regulation of cell growth GO:0030308 32 32 1,000 3,78E-03 0,03891431 ! lipid modification GO:0030258 32 32 1,000 3,78E-03 0,03869812 ! regulation of phospholipase activity GO:0010517 32 32 1,000 3,78E-03 0,03848432 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 3,78E-03 0,03827286 ! positive regulation of lipase activity GO:0060193 32 32 1,000 3,78E-03 0,03806372 ! negative regulation of cell size GO:0045792 33 33 1,000 4,016E-03 0,04022916 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 4,016E-03 0,0400117 ! regulation of bone remodeling GO:0046850 34 34 1,000 4,26E-03 0,04221036 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 4,26E-03 0,04198463 ! regulation of protein catabolic process GO:0042176 35 34 1,000 4,26E-03 0,04176131 ! regulation of cell morphogenesis GO:0022604 38 35 1,000 4,51E-03 0,04398136 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 4,51E-03 0,04374988 ! regulation of tissue remodeling GO:0034103 35 35 1,000 4,51E-03 0,04352082 ! regulation of immune effector process GO:0002697 35 35 1,000 4,51E-03 0,04329415 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 4,767E-03 0,04552408 GO:0045937|positive regulation of phosphate metabolic process, ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 4,767E-03 0,04528942 ! regulation of lipase activity GO:0060191 36 36 1,000 4,767E-03 0,04505716 ! meiosis GO:0007126 37 37 1,000 5,031E-03 0,04730647 GO:0051327|M phase of meiotic cell cycle, ! response to drug GO:0042493 37 37 1,000 5,031E-03 0,04706634 ! lung development GO:0030324 38 37 1,000 5,031E-03 0,04682863 ! negative regulation of growth GO:0045926 37 37 1,000 5,031E-03 0,04659331 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 5,031E-03 0,04636035 ! adaptive immune response GO:0002250 37 37 1,000 5,031E-03 0,0461297 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cell-matrix adhesion GO:0007160 39 38 1,000 5,301E-03 0,04836721 ! urogenital system development GO:0001655 38 38 1,000 5,301E-03 0,04812894 ! meiotic cell cycle GO:0051321 38 38 1,000 5,301E-03 0,04789302 ! regulation of homeostatic process GO:0032844 38 38 1,000 5,301E-03 0,04765939 ! respiratory tube development GO:0030323 40 39 1,000 5,578E-03 0,04990485 ! response to unfolded protein GO:0006986 39 39 1,000 5,578E-03 0,04966376 ! nucleotide-excision repair GO:0006289 40 39 1,000 5,578E-03 0,04942499 ! respiratory system development GO:0060541 40 39 1,000 5,578E-03 0,04918851 ! lymphocyte differentiation GO:0030098 39 39 1,000 5,578E-03 0,04895428 ! protein oligomerization GO:0051259 39 39 1,000 5,578E-03 0,04872227 ! cell cycle checkpoint GO:0000075 42 41 1,000 6,151E-03 0,05347606 ! regulation of caspase activity GO:0043281 41 41 1,000 6,151E-03 0,053225 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 6,448E-03 0,05552847 ! cell-substrate adhesion GO:0031589 43 42 1,000 6,448E-03 0,0552702 ! protein ubiquitination GO:0016567 43 42 1,000 6,448E-03 0,05501432 ! response to protein stimulus GO:0051789 42 42 1,000 6,448E-03 0,0547608 ! reproductive structure development GO:0048608 43 43 1,000 6,75E-03 0,05706932 ! mitochondrion organization GO:0007005 44 43 1,000 6,75E-03 0,05680873 ! protein import into nucleus GO:0006606 44 44 1,000 7,06E-03 0,0591405 ! nuclear import GO:0051170 45 45 1,000 7,375E-03 0,06150419 ! Wnt receptor signaling pathway GO:0016055 46 45 1,000 7,375E-03 0,06122714 ! regulation of peptidase activity GO:0052547 46 46 1,000 7,697E-03 0,06361252 ! sex differentiation GO:0007548 47 47 1,000 8,025E-03 0,06602831 ! regulation of catabolic process GO:0009894 48 47 1,000 8,025E-03 0,06573485 ! glycerophospholipid metabolic process GO:0006650 49 48 1,000 8,36E-03 0,06817084 ! protein localization in nucleus GO:0034504 48 48 1,000 8,36E-03 0,06787053 ! leukocyte differentiation GO:0002521 50 49 1,000 8,7E-03 0,07032602 ! gland development GO:0048732 51 49 1,000 8,7E-03 0,07001892 ! positive regulation of MAP kinase activity GO:0043406 50 49 1,000 8,7E-03 0,06971449 ! regulation of defense response GO:0031347 50 50 1,000 9,047E-03 0,07217941 ! regulation of DNA metabolic process GO:0051052 51 50 1,000 9,047E-03 0,0718683 ! negative regulation of transport GO:0051051 51 50 1,000 9,047E-03 0,07155985 ! T cell activation GO:0042110 51 50 1,000 9,047E-03 0,07125404 ! anatomical structure homeostasis GO:0060249 51 50 1,000 9,047E-03 0,07095083 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 9,047E-03 0,07065019 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 9,4E-03 0,07309654 ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 9,4E-03 0,07278942 GO:0051325|interphase, ! cell fate commitment GO:0045165 52 52 1,000 9,759E-03 0,07525346 ! response to hypoxia GO:0001666 53 53 1,000 0,01012397 0,07774362 ! protein amino acid dephosphorylation GO:0006470 55 54 1,000 0,01049511 0,08025931 ! response to oxygen levels GO:0070482 55 54 1,000 0,01049511 0,07992766 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,01049511 0,07959874 ! in utero embryonic development GO:0001701 55 55 1,000 0,01087227 0,08212125 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,01087227 0,08178606 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,01087227 0,0814536 ! reproductive developmental process GO:0003006 56 56 1,000 0,01125539 0,08398252 ! extracellular structure organization GO:0043062 56 56 1,000 0,01125539 0,08364388 ! dephosphorylation GO:0016311 60 59 1,000 0,01244025 0,09207781 ! peptidyl-amino acid modification GO:0018193 61 59 1,000 0,01244025 0,09170949 ! protein localization in organelle GO:0033365 59 59 1,000 0,01244025 0,09134412 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,01325938 0,09697238 ! morphogenesis of an epithelium GO:0002009 63 62 1,000 0,01367762 0,09963577 GO:0060429|epithelium development, ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,01367762 0,0992435 ! protein import GO:0017038 62 62 1,000 0,01367762 0,09885431 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,01410159 0,10152042 ! rRNA transcription GO:0009303 5 5 0,000 0,0144548 0,10365837 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,0144548 0,10325659 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,0144548 0,10285792 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,0144548 0,10246231 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,0144548 0,10206973 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,0144548 0,10168015 ! reproductive cellular process GO:0048610 5 5 0,000 0,0144548 0,10129354 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,0144548 0,10090985 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,0144548 0,10052906 ! metencephalon development GO:0022037 5 5 0,000 0,0144548 0,10015113 ! water transport GO:0006833 5 5 0,000 0,0144548 0,09977603 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,0144548 0,09940373 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,0144548 0,0990342 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,0144548 0,09866741 ! glycerol metabolic process GO:0006071 5 5 0,000 0,0144548 0,09830332 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,0144548 0,09794191 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,0144548 0,09758315 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,0144548 0,09722701 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,0144548 0,09687346 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,0144548 0,09652246 ! filopodium assembly GO:0046847 7 5 0,000 0,0144548 0,09617401 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,0144548 0,09582806 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,0144548 0,09548459 ! GTP metabolic process GO:0046039 5 5 0,000 0,0144548 0,09514357 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,0144548 0,09480498 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,0144548 0,09446879 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,0144548 0,09413498 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,0144548 0,09380352 ! social behavior GO:0035176 5 5 0,000 0,0144548 0,09347439 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,0144548 0,09314755 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,0144548 0,092823 ! memory GO:0007613 5 5 0,000 0,0144548 0,09250069 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,0144548 0,09218062 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,0144548 0,09186276 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,0144548 0,09154708 ! response to lipid GO:0033993 5 5 0,000 0,0144548 0,09123356 ! erythrocyte maturation GO:0043249 5 5 0,000 0,0144548 0,09092218 ! hippocampus development GO:0021766 6 5 0,000 0,0144548 0,09061293 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,0144548 0,09030576 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,0144548 0,09000068 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,0144548 0,08969764 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,0144548 0,08939664 ! mechanosensory behavior GO:0007638 5 5 0,000 0,0144548 0,08909766 ! heart looping GO:0001947 5 5 0,000 0,0144548 0,08880067 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,0144548 0,08850565 ! response to interferon-gamma GO:0034341 5 5 0,000 0,0144548 0,08821258 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,0144548 0,08792145 ! endocrine pancreas development GO:0031018 5 5 0,000 0,0144548 0,08763224 ! pH reduction GO:0045851 5 5 0,000 0,0144548 0,08734492 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,0144548 0,08705948 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,0144548 0,0867759 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,0144548 0,08649416 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,0144548 0,08621424 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,0144548 0,08593613 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,0144548 0,08565981 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,0144548 0,08538526 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,0144548 0,08511246 ! adrenal gland development GO:0030325 5 5 0,000 0,0144548 0,0848414 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,0144548 0,08457206 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,0144548 0,08430443 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,0144548 0,08403849 ! astrocyte differentiation GO:0048708 5 5 0,000 0,0144548 0,08377421 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,0144548 0,0835116 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,0144548 0,08325063 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,0144548 0,08299128 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,0144548 0,08273354 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,0144548 0,0824774 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,0144548 0,08222284 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,0144548 0,08196985 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,0144548 0,08171841 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,0144548 0,0814685 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,0144548 0,08122012 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,0144548 0,08097325 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,0144548 0,08072788 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,0144548 0,08048399 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,0144548 0,08024157 ! response to ATP GO:0033198 5 5 0,000 0,0144548 0,0800006 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,0144548 0,07976108 ! regulation of appetite GO:0032098 5 5 0,000 0,0144548 0,07952299 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,0144548 0,07928631 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,0144548 0,07905104 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,0144548 0,07881716 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,0144548 0,07858466 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,0144548 0,07835353 ! receptor clustering GO:0043113 5 5 0,000 0,0144548 0,07812375 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,0144548 0,07789532 ! fear response GO:0042596 5 5 0,000 0,0144548 0,07766822 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,0144548 0,07744244 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,0144548 0,07721797 ! retinol metabolic process GO:0042572 5 5 0,000 0,0144548 0,0769948 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,0144548 0,07677291 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,0144548 0,0765523 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,0144548 0,07633295 ! parturition GO:0007567 5 5 0,000 0,0144548 0,07611486 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0144548 0,07589801 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,0144548 0,07568239 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,0144548 0,07546799 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,0144548 0,0752548 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,0144548 0,07504282 ! protein heterooligomerization GO:0051291 5 5 0,000 0,0144548 0,07483202 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,0144548 0,07462241 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,0144548 0,07441397 ! response to UV-B GO:0010224 5 5 0,000 0,0144548 0,07420669 ! oligodendrocyte development GO:0014003 5 5 0,000 0,0144548 0,07400056 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,0144548 0,07379557 ! activated T cell proliferation GO:0050798 5 5 0,000 0,0144548 0,07359171 ! interaction with symbiont GO:0051702 5 5 0,000 0,0144548 0,07338898 ! cellular extravasation GO:0045123 5 5 0,000 0,0144548 0,07318736 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,0144548 0,07298685 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,0144548 0,07278743 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,0144548 0,0725891 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,0144548 0,07239185 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,0144548 0,07219566 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,0144548 0,07200054 ! response to amine stimulus GO:0014075 5 5 0,000 0,0144548 0,07180647 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,0144548 0,07161344 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,0144548 0,07142145 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,0144548 0,07123048 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,0144548 0,07104053 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,0144548 0,0708516 ! neuron recognition GO:0008038 5 5 0,000 0,0144548 0,07066366 ! decidualization GO:0046697 5 5 0,000 0,0144548 0,07047672 ! hair follicle maturation GO:0048820 5 5 0,000 0,0144548 0,07029077 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,0144548 0,07010579 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,0144548 0,06992179 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,0144548 0,06973874 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,0144548 0,06955666 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,0144548 0,06937552 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,0144548 0,06919533 ! postreplication repair GO:0006301 5 5 0,000 0,0144548 0,06901606 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,0144548 0,06883773 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,0144548 0,06866031 ! histone methylation GO:0016571 5 5 0,000 0,0144548 0,06848381 ! DNA methylation GO:0006306 5 5 0,000 0,0144548 0,06830821 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,0144548 0,0681335 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,0144548 0,06795969 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,0144548 0,06778677 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,0144548 0,06761472 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,0144548 0,06744354 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,0144548 0,06727323 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,0144548 0,06710378 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,0144548 0,06693518 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,0144548 0,06676742 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,0144548 0,0666005 ! sterol catabolic process GO:0016127 5 5 0,000 0,0144548 0,06643441 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,0144548 0,06626915 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,0144548 0,06610472 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,0144548 0,06594109 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,0144548 0,06577827 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,0144548 0,06561626 ! zymogen activation GO:0031638 5 5 0,000 0,0144548 0,06545504 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,0144548 0,06529461 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,0144548 0,06513496 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,0144548 0,0649761 ! peptidyl-lysine modification GO:0018205 5 5 0,000 0,0144548 0,06481801 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,0144548 0,06466068 ! nucleosome positioning GO:0016584 5 5 0,000 0,0144548 0,06450412 ! regulation of isotype switching GO:0045191 5 5 0,000 0,0144548 0,06434831 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,0144548 0,06419325 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,0144548 0,06403894 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,0144548 0,06388537 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,0144548 0,06373254 ! NADPH regeneration GO:0006740 5 5 0,000 0,0144548 0,06358043 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,0144548 0,06342905 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,0144548 0,06327839 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,0144548 0,06312844 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,0144548 0,0629792 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,0144548 0,06283066 ! sarcomere organization GO:0045214 5 5 0,000 0,0144548 0,06268282 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,0144548 0,06253568 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,0144548 0,06238923 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,0144548 0,06224346 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,0144548 0,06209837 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,0144548 0,06195395 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,0144548 0,06181021 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,0144548 0,06166713 ! spleen development GO:0048536 5 5 0,000 0,0144548 0,06152471 ! male genitalia development GO:0030539 5 5 0,000 0,0144548 0,06138295 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,0144548 0,06124184 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,0144548 0,06110138 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,0144548 0,06096156 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,0144548 0,06082237 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,0144548 0,06068383 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,0144548 0,06054591 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,0144548 0,06040862 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,0144548 0,06027195 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,0144548 0,06013589 ! ATP catabolic process GO:0006200 5 5 0,000 0,0144548 0,06000045 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,0144548 0,05986562 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,0144548 0,05973139 ! blastocyst formation GO:0001825 5 5 0,000 0,0144548 0,05959776 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,0144548 0,05946473 ! embryonic gut development GO:0048566 5 5 0,000 0,0144548 0,05933229 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,0144548 0,05920044 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,0144548 0,05906918 ! activation of innate immune response GO:0002218 5 5 0,000 0,0144548 0,0589385 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,0144548 0,05880839 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,0144548 0,05867885 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,0144548 0,05854989 ! muscle adaptation GO:0043500 5 5 0,000 0,0144548 0,05842149 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,0144548 0,05829365 ! embryonic heart tube development GO:0035050 5 5 0,000 0,0144548 0,05816638 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,0144548 0,05803965 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,0144548 0,05791348 ! defense response to fungus GO:0050832 5 5 0,000 0,0144548 0,05778785 ! lysogeny GO:0030069 5 5 0,000 0,0144548 0,05766277 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,0144548 0,05753823 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,0144548 0,05741422 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,0144548 0,05729075 ! response to nicotine GO:0035094 5 5 0,000 0,0144548 0,05716781 ! establishment of cell polarity GO:0030010 5 5 0,000 0,0144548 0,0570454 ! mitochondrion localization GO:0051646 5 5 0,000 0,0144548 0,0569235 ! nucleus localization GO:0051647 5 5 0,000 0,0144548 0,05680213 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,0144548 0,05668128 ! glycerolipid metabolic process GO:0046486 65 64 1,000 0,01453126 0,05686011 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,01453126 0,05673964 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,01453126 0,05661968 ! regulation of MAP kinase activity GO:0043405 67 66 1,000 0,01540757 0,05990749 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,01540757 0,05978137 ! striated muscle tissue development GO:0014706 69 67 1,000 0,01585414 0,06138484 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,01585414 0,06125616 ! Ras protein signal transduction GO:0007265 69 67 1,000 0,01585414 0,061128 ! regionalization GO:0003002 70 69 1,000 0,01676396 0,06450101 ! response to nutrient levels GO:0031667 69 69 1,000 0,01676396 0,06436664 ! regulation of mitotic cell cycle GO:0007346 72 69 1,000 0,01676396 0,06423282 ! positive regulation of transport GO:0051050 71 70 1,000 0,01722715 0,0658706 ! growth GO:0040007 70 70 1,000 0,01722715 0,06573422 ! muscle tissue development GO:0060537 72 70 1,000 0,01722715 0,06559841 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,01732184 0,065823 ! axon extension GO:0048675 7 6 0,000 0,01732184 0,06568756 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,01732184 0,06555268 ! N-terminal protein amino acid modification GO:0031365 6 6 0,000 0,01732184 0,06541835 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 0,000 0,01732184 0,06528457 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,01732184 0,06515134 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,01732184 0,06501865 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,01732184 0,0648865 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,01732184 0,06475488 ! virus-host interaction GO:0019048 6 6 0,000 0,01732184 0,0646238 ! regulation of S phase GO:0033261 6 6 0,000 0,01732184 0,06449324 ! myotube differentiation GO:0014902 6 6 0,000 0,01732184 0,06436322 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,01732184 0,06423371 ! bone remodeling GO:0046849 6 6 0,000 0,01732184 0,06410473 ! N-glycan processing GO:0006491 6 6 0,000 0,01732184 0,06397626 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,01732184 0,06384831 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,01732184 0,06372087 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,01732184 0,06359394 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,01732184 0,06346751 ! RNA methylation GO:0001510 6 6 0,000 0,01732184 0,06334158 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,01732184 0,06321615 ! succinate metabolic process GO:0006105 7 6 0,000 0,01732184 0,06309122 ! artery development GO:0060840 6 6 0,000 0,01732184 0,06296678 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,01732184 0,06284283 ! bile acid metabolic process GO:0008206 6 6 0,000 0,01732184 0,06271936 ! androgen metabolic process GO:0008209 6 6 0,000 0,01732184 0,06259638 ! estrogen metabolic process GO:0008210 6 6 0,000 0,01732184 0,06247389 ! limbic system development GO:0021761 7 6 0,000 0,01732184 0,06235187 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,01732184 0,06223032 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,01732184 0,06210925 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,01732184 0,06198865 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,01732184 0,06186852 ! pathogenesis GO:0009405 6 6 0,000 0,01732184 0,06174885 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,01732184 0,06162964 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,01732184 0,0615109 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,01732184 0,06139261 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,01732184 0,06127477 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,01732184 0,06115739 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,01732184 0,06104045 ! arginine metabolic process GO:0006525 6 6 0,000 0,01732184 0,06092396 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,01732184 0,06080792 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,01732184 0,06069231 ! glutamate catabolic process GO:0006538 7 6 0,000 0,01732184 0,06057715 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,01732184 0,06046242 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,01732184 0,06034812 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,01732184 0,06023426 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,01732184 0,06012082 ! V(D)J recombination GO:0033151 6 6 0,000 0,01732184 0,06000781 ! focal adhesion formation GO:0048041 7 6 0,000 0,01732184 0,05989523 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,01732184 0,05978306 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 0,01732184 0,05967132 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,01732184 0,05955999 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,01732184 0,05944908 ! regulation of heart rate GO:0002027 6 6 0,000 0,01732184 0,05933858 ! lipid digestion GO:0044241 6 6 0,000 0,01732184 0,05922849 ! asymmetric protein localization GO:0008105 6 6 0,000 0,01732184 0,05911881 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,01732184 0,05900953 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,01732184 0,05890066 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,01732184 0,05879218 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,01732184 0,05868411 ! ruffle organization GO:0031529 6 6 0,000 0,01732184 0,05857643 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,01732184 0,05846915 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,01732184 0,05836226 ! neutral amino acid transport GO:0015804 6 6 0,000 0,01732184 0,05825576 ! L-amino acid transport GO:0015807 6 6 0,000 0,01732184 0,05814965 ! bone mineralization GO:0030282 6 6 0,000 0,01732184 0,05804392 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,01732184 0,05793858 ! negative regulation of ossification GO:0030279 6 6 0,000 0,01732184 0,05783362 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,01732184 0,05772903 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,01732184 0,05762483 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,01732184 0,057521 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,01732184 0,05741755 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,01732184 0,05731446 ! regulation of organ growth GO:0046620 6 6 0,000 0,01732184 0,05721175 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,01732184 0,0571094 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,01732184 0,05700742 ! response to dsRNA GO:0043331 6 6 0,000 0,01732184 0,0569058 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,01732184 0,05680455 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,01732184 0,05670365 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 0,01732184 0,05660311 ! genitalia development GO:0048806 6 6 0,000 0,01732184 0,05650293 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,01732184 0,0564031 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,01732184 0,05630363 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 0,01732184 0,0562045 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,01732184 0,05610572 ! multicellular organismal aging GO:0010259 6 6 0,000 0,01732184 0,05600729 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,01732184 0,0559092 ! erythrocyte development GO:0048821 6 6 0,000 0,01732184 0,05581146 ! renal water homeostasis GO:0003091 6 6 0,000 0,01732184 0,05571406 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,01732184 0,055617 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,01732184 0,05552027 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,01732184 0,05542388 ! ribosome assembly GO:0042255 6 6 0,000 0,01732184 0,05532783 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,01732184 0,0552321 ! diencephalon development GO:0021536 6 6 0,000 0,01732184 0,05513671 ! fucose catabolic process GO:0019317 6 6 0,000 0,01732184 0,05504165 GO:0042355|L-fucose catabolic process, ! protein sumoylation GO:0016925 6 6 0,000 0,01732184 0,05494691 ! regulation of lipid transport GO:0032368 6 6 0,000 0,01732184 0,0548525 ! regulation of cell division GO:0051302 6 6 0,000 0,01732184 0,05475841 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,01732184 0,05466465 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,01732184 0,05457121 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,01732184 0,05447808 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,01732184 0,05438527 ! neuroblast proliferation GO:0007405 6 6 0,000 0,01732184 0,05429278 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,01732184 0,0542006 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,01732184 0,05410874 ! regulation of glucose transport GO:0010827 6 6 0,000 0,01732184 0,05401718 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,01732184 0,05392594 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,01732184 0,053835 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,01732184 0,05374437 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,01732184 0,05365404 ! thymus development GO:0048538 6 6 0,000 0,01732184 0,05356402 ! lymph node development GO:0048535 6 6 0,000 0,01732184 0,0534743 ! organic cation transport GO:0015695 6 6 0,000 0,01732184 0,05338488 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,01732184 0,05329575 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,01732184 0,05320693 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,01732184 0,0531184 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,01732184 0,05303016 ! sperm-egg recognition GO:0035036 7 6 0,000 0,01732184 0,05294222 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,01732184 0,05285456 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,01732184 0,0527672 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,01732184 0,05268013 ! alditol metabolic process GO:0019400 6 6 0,000 0,01732184 0,05259334 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,01732184 0,05250684 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,01732184 0,05242062 ! maternal placenta development GO:0001893 6 6 0,000 0,01732184 0,05233468 ! regulation of embryonic development GO:0045995 6 6 0,000 0,01732184 0,05224903 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,01732184 0,05216365 ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,0176958 0,05320286 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,01816989 0,05453926 ! response to oxidative stress GO:0006979 76 75 1,000 0,01962447 0,05880959 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,02011999 0,06019667 ! respiratory burst GO:0045730 7 7 0,000 0,02018096 0,06028121 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,02018096 0,06018367 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,02018096 0,06008644 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,02018096 0,05998953 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,02018096 0,05989293 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,02018096 0,05979663 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,02018096 0,05970065 ! regulation of chemokine production GO:0032642 7 7 0,000 0,02018096 0,05960498 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,02018096 0,05950961 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,02018096 0,05941455 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,02018096 0,05931979 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,02018096 0,05922533 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,02018096 0,05913117 ! gene silencing by RNA GO:0031047 7 7 0,000 0,02018096 0,05903731 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,02018096 0,05894375 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,02018096 0,05885049 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,02018096 0,05875751 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,02018096 0,05866484 ! axis specification GO:0009798 7 7 0,000 0,02018096 0,05857245 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,02018096 0,05848036 ! visual behavior GO:0007632 7 7 0,000 0,02018096 0,05838855 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,02018096 0,05829703 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,02018096 0,0582058 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,02018096 0,05811485 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,02018096 0,05802419 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,02018096 0,05793381 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,02018096 0,05784371 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,02018096 0,05775389 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,02018096 0,05766435 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,02018096 0,05757509 ! digestive system development GO:0055123 7 7 0,000 0,02018096 0,0574861 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,02018096 0,05739739 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,02018096 0,05730895 ! protein targeting to ER GO:0045047 8 7 0,000 0,02018096 0,05722078 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,02018096 0,05713288 ! endoderm development GO:0007492 7 7 0,000 0,02018096 0,05704526 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,02018096 0,0569579 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,02018096 0,05687081 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,02018096 0,05678398 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,02018096 0,05669742 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,02018096 0,05661112 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 0,02018096 0,05652509 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,02018096 0,05643931 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,02018096 0,0563538 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,02018096 0,05626854 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,02018096 0,05618354 ! UV protection GO:0009650 7 7 0,000 0,02018096 0,0560988 ! DNA integration GO:0015074 7 7 0,000 0,02018096 0,05601432 ! myofibril assembly GO:0030239 7 7 0,000 0,02018096 0,05593009 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,02018096 0,05584611 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,02018096 0,05576238 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,02018096 0,0556789 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,02018096 0,05559568 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,02018096 0,0555127 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,02018096 0,05542997 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,02018096 0,05534748 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,02018096 0,05526524 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,02018096 0,05518324 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,02018096 0,05510149 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,02018096 0,05501998 ! axon cargo transport GO:0008088 7 7 0,000 0,02018096 0,05493871 ! eating behavior GO:0042755 7 7 0,000 0,02018096 0,05485768 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,02018096 0,05477689 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,02018096 0,05469633 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,02018096 0,05461602 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,02018096 0,05453593 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,02018096 0,05445609 ! cranial nerve development GO:0021545 7 7 0,000 0,02018096 0,05437647 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,02018096 0,05429709 ! induction of an organ GO:0001759 7 7 0,000 0,02018096 0,05421794 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,02018096 0,05413902 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,02018096 0,05406033 ! autonomic nervous system development GO:0048483 7 7 0,000 0,02018096 0,05398187 ! intracellular lipid transport GO:0032365 7 7 0,000 0,02018096 0,05390363 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,02018096 0,05382562 ! platelet activation GO:0030168 8 7 0,000 0,02018096 0,05374784 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,02018096 0,05367028 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,02018096 0,05359295 ! natural killer cell activation GO:0030101 7 7 0,000 0,02018096 0,05351584 ! NADP metabolic process GO:0006739 7 7 0,000 0,02018096 0,05343895 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,02018096 0,05336228 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,02018096 0,05328583 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,02018096 0,05320959 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,02018096 0,05313358 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,02018096 0,05305778 ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,02018096 0,0529822 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,02018096 0,05290684 ! cell-cell recognition GO:0009988 8 7 0,000 0,02018096 0,05283169 ! hormone catabolic process GO:0042447 7 7 0,000 0,02018096 0,05275675 ! dopamine metabolic process GO:0042417 7 7 0,000 0,02018096 0,05268202 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,02018096 0,05260751 ! oxygen transport GO:0015671 7 7 0,000 0,02018096 0,0525332 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,02018096 0,05245911 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,02018096 0,05238522 ! regulation of axon extension GO:0030516 7 7 0,000 0,02018096 0,05231154 ! cell killing GO:0001906 7 7 0,000 0,02018096 0,05223807 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,02018096 0,05216481 ! adult feeding behavior GO:0008343 7 7 0,000 0,02018096 0,05209175 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,02018096 0,05201889 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,02018096 0,05194624 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,02018096 0,05187379 ! negative regulation of T cell activation GO:0050868 7 7 0,000 0,02018096 0,05180154 ! response to cold GO:0009409 7 7 0,000 0,02018096 0,05172949 ! regulation of protein modification process GO:0031399 79 78 1,000 0,02112684 0,05407885 ! microtubule-based movement GO:0007018 82 78 1,000 0,02112684 0,05400385 ! regulation of immune response GO:0050776 78 78 1,000 0,02112684 0,05392905 ! nuclear transport GO:0051169 79 79 1,000 0,02163811 0,05515772 GO:0006913|nucleocytoplasmic transport, ! neuron projection development GO:0031175 85 80 1,000 0,02215456 0,0563962 ! tube development GO:0035295 83 81 1,000 0,02267616 0,05764436 ! lymphocyte activation GO:0046649 82 81 1,000 0,02267616 0,05756496 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,02303217 0,0583883 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,02303217 0,05830809 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,02303217 0,05822811 ! positive regulation of translation GO:0045727 8 8 0,000 0,02303217 0,05814834 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,02303217 0,0580688 ! superoxide anion generation GO:0042554 8 8 0,000 0,02303217 0,05798947 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,02303217 0,05791036 ! cGMP metabolic process GO:0046068 8 8 0,000 0,02303217 0,05783146 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,02303217 0,05775278 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,02303217 0,05767431 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,02303217 0,05759605 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,02303217 0,05751801 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,02303217 0,05744018 ! zinc ion transport GO:0006829 8 8 0,000 0,02303217 0,05736255 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,02303217 0,05728514 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,02303217 0,05720794 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,02303217 0,05713094 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,02303217 0,05705415 ! lipid localization GO:0010876 8 8 0,000 0,02303217 0,05697757 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,02303217 0,05690119 ! response to cAMP GO:0051591 8 8 0,000 0,02303217 0,05682502 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,02303217 0,05674905 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,02303217 0,05667329 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,02303217 0,05659772 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,02303217 0,05652236 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,02303217 0,05644719 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,02303217 0,05637223 ! sensory perception of taste GO:0050909 8 8 0,000 0,02303217 0,05629747 ! organelle fusion GO:0048284 8 8 0,000 0,02303217 0,0562229 ! pancreas development GO:0031016 8 8 0,000 0,02303217 0,05614853 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,02303217 0,05607436 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,02303217 0,05600038 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,02303217 0,0559266 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,02303217 0,05585301 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,02303217 0,05577962 ! sperm motility GO:0030317 8 8 0,000 0,02303217 0,05570642 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,02303217 0,05563341 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,02303217 0,05556059 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,02303217 0,05548796 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,02303217 0,05541552 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,02303217 0,05534327 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,02303217 0,05527121 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,02303217 0,05519934 ! Golgi organization GO:0007030 8 8 0,000 0,02303217 0,05512765 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,02303217 0,05505615 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,02303217 0,05498483 ! fructose metabolic process GO:0006000 8 8 0,000 0,02303217 0,0549137 ! mannose metabolic process GO:0006013 9 8 0,000 0,02303217 0,05484275 ! NAD metabolic process GO:0019674 8 8 0,000 0,02303217 0,05477199 ! sex determination GO:0007530 8 8 0,000 0,02303217 0,05470141 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,02303217 0,054631 ! plasma membrane fusion GO:0045026 8 8 0,000 0,02303217 0,05456078 ! response to fungus GO:0009620 8 8 0,000 0,02303217 0,05449075 ! stem cell differentiation GO:0048863 8 8 0,000 0,02303217 0,05442089 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,02303217 0,0543512 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,02303217 0,0542817 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,02303217 0,05421238 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,02303217 0,05414323 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,02303217 0,05407426 ! regulation of vasodilation GO:0042312 8 8 0,000 0,02303217 0,05400546 ! vasoconstriction GO:0042310 8 8 0,000 0,02303217 0,05393684 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,02303217 0,05386839 ! muscle cell development GO:0055001 8 8 0,000 0,02303217 0,05380011 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,02303217 0,05373201 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,02303217 0,05366408 ! sensory perception of pain GO:0019233 8 8 0,000 0,02303217 0,05359633 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,02303217 0,05352874 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,02303217 0,05346132 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,02303217 0,05339408 ! chromatin silencing GO:0006342 8 8 0,000 0,02303217 0,053327 ! tissue regeneration GO:0042246 8 8 0,000 0,02303217 0,05326009 ! salivary gland development GO:0007431 8 8 0,000 0,02303217 0,05319335 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,02303217 0,05312677 ! T cell homeostasis GO:0043029 8 8 0,000 0,02303217 0,05306036 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,02303217 0,05299412 ! water homeostasis GO:0030104 8 8 0,000 0,02303217 0,05292804 ! cofactor transport GO:0051181 8 8 0,000 0,02303217 0,05286213 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,02303217 0,05279638 ! acid secretion GO:0046717 8 8 0,000 0,02303217 0,0527308 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,02303217 0,05266537 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,02303217 0,05260011 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,02303217 0,05253501 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,02303217 0,05247007 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,02303217 0,0524053 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,02303217 0,05234068 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,02303217 0,05227622 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,02303217 0,05221192 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,02303217 0,05214778 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,02303217 0,05208379 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,02303217 0,05201996 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,02303217 0,05195629 ! developmental induction GO:0031128 8 8 0,000 0,02303217 0,05189278 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,02303217 0,05182941 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,02303217 0,05176621 ! actin filament polymerization GO:0030041 9 8 0,000 0,02303217 0,05170316 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,02303217 0,05164026 ! peptide hormone processing GO:0016486 8 8 0,000 0,02303217 0,05157751 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,02303217 0,05151492 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,02303217 0,05145247 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,02481348 0,05536469 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 0,02481348 0,05529775 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,02481348 0,05523096 ! positive regulation of protein kinase activity GO:0045860 89 86 1,000 0,02536038 0,05638019 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 1,000 0,02536038 0,05631226 ! organophosphate metabolic process GO:0019637 87 86 1,000 0,02536038 0,0562445 GO:0006644|phospholipid metabolic process, ! lactation GO:0007595 10 9 0,000 0,0258755 0,05731796 ! embryonic pattern specification GO:0009880 10 9 0,000 0,0258755 0,05724915 ! positive regulation of cell size GO:0045793 9 9 0,000 0,0258755 0,05718051 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,0258755 0,05711203 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,0258755 0,05704372 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,0258755 0,05697556 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,0258755 0,05690757 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,0258755 0,05683974 ! viral genome replication GO:0019079 9 9 0,000 0,0258755 0,05677208 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,0258755 0,05670457 ! copper ion transport GO:0006825 9 9 0,000 0,0258755 0,05663723 ! lipid phosphorylation GO:0046834 9 9 0,000 0,0258755 0,05657004 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,0258755 0,05650302 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,0258755 0,05643615 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,0258755 0,05636944 ! RNA polyadenylation GO:0043631 9 9 0,000 0,0258755 0,05630289 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,0258755 0,05623649 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,0258755 0,05617025 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,0258755 0,05610417 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,0258755 0,05603824 ! phospholipid efflux GO:0033700 9 9 0,000 0,0258755 0,05597247 ! response to alkaloid GO:0043279 10 9 0,000 0,0258755 0,05590685 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,0258755 0,05584139 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,0258755 0,05577608 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,0258755 0,05571092 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,0258755 0,05564591 ! response to ethanol GO:0045471 9 9 0,000 0,0258755 0,05558106 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,0258755 0,05551635 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,0258755 0,0554518 ! methionine metabolic process GO:0006555 9 9 0,000 0,0258755 0,05538739 ! glutamine metabolic process GO:0006541 9 9 0,000 0,0258755 0,05532314 ! cerebral cortex development GO:0021987 9 9 0,000 0,0258755 0,05525903 ! response to osmotic stress GO:0006970 9 9 0,000 0,0258755 0,05519508 ! pigmentation during development GO:0048066 9 9 0,000 0,0258755 0,05513127 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,0258755 0,0550676 ! central nervous system neuron development GO:0021954 10 9 0,000 0,0258755 0,05500409 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,0258755 0,05494072 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,0258755 0,0548775 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,0258755 0,05481442 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,0258755 0,05475149 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,0258755 0,0546887 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,0258755 0,05462605 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,0258755 0,05456355 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,0258755 0,0545012 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,0258755 0,05443898 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,0258755 0,05437691 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,0258755 0,05431497 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,0258755 0,05425318 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,0258755 0,05419153 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,0258755 0,05413002 ! DNA replication initiation GO:0006270 9 9 0,000 0,0258755 0,05406865 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,0258755 0,05400741 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,0258755 0,05394632 ! histone acetylation GO:0016573 9 9 0,000 0,0258755 0,05388536 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,0258755 0,05382454 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,0258755 0,05376386 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,0258755 0,05370332 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,0258755 0,05364291 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,0258755 0,05358264 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,0258755 0,0535225 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,0258755 0,0534625 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,0258755 0,05340263 ! collagen catabolic process GO:0030574 9 9 0,000 0,0258755 0,05334289 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,0258755 0,05328329 ! purine base metabolic process GO:0006144 9 9 0,000 0,0258755 0,05322382 ! gas transport GO:0015669 9 9 0,000 0,0258755 0,05316449 ! cholesterol efflux GO:0033344 9 9 0,000 0,0258755 0,05310528 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,0258755 0,05304621 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,0258755 0,05298727 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,0258755 0,05292846 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,0258755 0,05286978 ! defense response to virus GO:0051607 9 9 0,000 0,0258755 0,05281124 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,0258755 0,05275282 ! actin filament-based movement GO:0030048 9 9 0,000 0,0258755 0,05269453 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,0258755 0,05263636 ! heart development GO:0007507 90 87 1,000 0,02591225 0,052653 ! male gamete generation GO:0048232 90 88 1,000 0,02646906 0,05372519 GO:0007283|spermatogenesis, ! positive regulation of transferase activity GO:0051347 91 88 1,000 0,02646906 0,05366609 GO:0033674|positive regulation of kinase activity, ! brain development GO:0007420 91 90 1,000 0,02759737 0,05589225 ! DNA replication GO:0006260 91 91 1,000 0,02816881 0,05698695 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,02871097 0,05802008 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,02871097 0,05795653 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,02871097 0,05789312 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,02871097 0,05782985 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,02871097 0,05776671 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,02871097 0,05770372 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,02871097 0,05764086 ! neuron maturation GO:0042551 10 10 0,000 0,02871097 0,05757814 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,02871097 0,05751555 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,02871097 0,05745311 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,02871097 0,05739079 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,02871097 0,05732861 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,02871097 0,05726657 ! hormone secretion GO:0046879 10 10 0,000 0,02871097 0,05720466 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,02871097 0,05714288 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,02871097 0,05708124 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! cAMP metabolic process GO:0046058 10 10 0,000 0,02871097 0,05701973 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,02871097 0,05695835 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,02871097 0,05689711 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,02871097 0,05683599 ! glial cell development GO:0021782 10 10 0,000 0,02871097 0,05677501 ! phototransduction GO:0007602 11 10 0,000 0,02871097 0,05671416 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,02871097 0,05665344 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,02871097 0,05659285 ! fat cell differentiation GO:0045444 10 10 0,000 0,02871097 0,05653238 ! myoblast differentiation GO:0045445 10 10 0,000 0,02871097 0,05647205 ! centrosome cycle GO:0007098 10 10 0,000 0,02871097 0,05641184 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,02871097 0,05635177 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,02871097 0,05629182 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,02871097 0,056232 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,02871097 0,0561723 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,02871097 0,05611274 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,02871097 0,0560533 ! protein polyubiquitination GO:0000209 10 10 0,000 0,02871097 0,05599398 ! glutamate metabolic process GO:0006536 11 10 0,000 0,02871097 0,05593479 ! plasma membrane organization GO:0007009 10 10 0,000 0,02871097 0,05587572 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,02871097 0,05581678 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,02871097 0,05575797 ! lysosomal transport GO:0007041 10 10 0,000 0,02871097 0,05569927 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,02871097 0,05564071 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,02871097 0,05558226 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,02871097 0,05552394 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,02871097 0,05546573 ! exocrine system development GO:0035272 10 10 0,000 0,02871097 0,05540765 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,02871097 0,0553497 ! neuromuscular junction development GO:0007528 10 10 0,000 0,02871097 0,05529186 ! embryo implantation GO:0007566 11 10 0,000 0,02871097 0,05523414 ! regulation of protein binding GO:0043393 11 10 0,000 0,02871097 0,05517655 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,02871097 0,05511907 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,02871097 0,05506172 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,02871097 0,05500448 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,02871097 0,05494736 ! protein export from nucleus GO:0006611 10 10 0,000 0,02871097 0,05489036 ! negative regulation of immune response GO:0050777 10 10 0,000 0,02871097 0,05483348 ! cytolysis GO:0019835 10 10 0,000 0,02871097 0,05477672 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,02871097 0,05472007 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,02871097 0,05466354 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,02871097 0,05460713 ! histone deacetylation GO:0016575 10 10 0,000 0,02871097 0,05455084 ! mRNA splice site selection GO:0006376 11 10 0,000 0,02871097 0,05449466 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,02871097 0,05443859 ! gland morphogenesis GO:0022612 10 10 0,000 0,02871097 0,05438264 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,02871097 0,05432681 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,02871097 0,05427109 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,02871097 0,05421548 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,02871097 0,05415999 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,02871097 0,05410461 ! regulation of epidermis development GO:0045682 10 10 0,000 0,02871097 0,05404935 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,02871097 0,05399419 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,02871097 0,05393915 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,02871097 0,05388423 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,02871097 0,05382941 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,02871097 0,05377471 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,02871097 0,05372011 ! nerve development GO:0021675 10 10 0,000 0,02871097 0,05366563 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,02871097 0,05361126 ! gut development GO:0048565 10 10 0,000 0,02871097 0,05355699 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,02871097 0,05350284 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,02871097 0,0534488 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,02871097 0,05339486 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,02871097 0,05334104 ! protein stabilization GO:0050821 10 10 0,000 0,02871097 0,05328732 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,02874506 0,05329693 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,02874506 0,05324337 ! tissue morphogenesis GO:0048729 94 93 1,000 0,02932611 0,05426508 ! regulation of response to stress GO:0080134 97 94 1,000 0,02991191 0,05529354 ! pattern specification process GO:0007389 96 94 1,000 0,02991191 0,05523813 ! epidermis development GO:0008544 94 94 1,000 0,02991191 0,05518284 ! protein secretion GO:0009306 11 11 0,000 0,03153859 0,05812562 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,03153859 0,05806756 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,03153859 0,0580096 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,03153859 0,05795177 ! negative regulation of defense response GO:0031348 11 11 0,000 0,03153859 0,05789405 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,03153859 0,05783644 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,03153859 0,05777895 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,03153859 0,05772157 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,03153859 0,05766431 ! skin development GO:0043588 11 11 0,000 0,03153859 0,05760716 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,03153859 0,05755012 ! signal complex assembly GO:0007172 11 11 0,000 0,03153859 0,0574932 ! peroxisomal transport GO:0043574 11 11 0,000 0,03153859 0,05743639 ! protein amino acid methylation GO:0006479 11 11 0,000 0,03153859 0,05737969 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 0,000 0,03153859 0,0573231 ! heart contraction GO:0060047 11 11 0,000 0,03153859 0,05726662 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,03153859 0,05721026 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,03153859 0,057154 ! T cell proliferation GO:0042098 11 11 0,000 0,03153859 0,05709786 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,03153859 0,05704183 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,03153859 0,0569859 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,03153859 0,05693009 ! spinal cord development GO:0021510 11 11 0,000 0,03153859 0,05687439 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,03153859 0,05681879 ! smooth muscle contraction GO:0006939 11 11 0,000 0,03153859 0,0567633 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,03153859 0,05670792 ! digestive system process GO:0022600 11 11 0,000 0,03153859 0,05665265 ! mitotic spindle organization GO:0007052 11 11 0,000 0,03153859 0,05659749 ! fucose metabolic process GO:0006004 11 11 0,000 0,03153859 0,05654243 ! membrane budding GO:0006900 11 11 0,000 0,03153859 0,05648749 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,03153859 0,05643264 ! monoamine transport GO:0015844 11 11 0,000 0,03153859 0,05637791 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,03153859 0,05632328 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,03153859 0,05626875 ! body fluid secretion GO:0007589 11 11 0,000 0,03153859 0,05621434 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,03153859 0,05616002 ! intermediate filament-based process GO:0045103 11 11 0,000 0,03153859 0,05610581 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,03153859 0,05605171 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,03153859 0,05599771 ! membrane depolarization GO:0051899 11 11 0,000 0,03153859 0,05594381 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,03153859 0,05589002 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,03153859 0,05583633 ! oogenesis GO:0048477 11 11 0,000 0,03153859 0,05578275 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,03153859 0,05572926 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,03153859 0,05567588 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,03153859 0,05562261 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,03153859 0,05556943 ! muscle maintenance GO:0046716 12 11 0,000 0,03153859 0,05551635 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,03153859 0,05546338 ! hindbrain development GO:0030902 11 11 0,000 0,03153859 0,05541051 ! steroid catabolic process GO:0006706 11 11 0,000 0,03153859 0,05535774 ! endocrine process GO:0050886 11 11 0,000 0,03153859 0,05530506 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,03153859 0,05525249 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,03153859 0,05520002 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,03153859 0,05514765 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,03153859 0,05509538 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,03153859 0,0550432 ! blood circulation GO:0008015 99 98 1,000 0,03230212 0,05632242 GO:0003013|circulatory system process, ! ectoderm development GO:0007398 99 99 1,000 0,03291127 0,05733031 ! muscle organ development GO:0007517 102 100 1,000 0,033525 0,05834427 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,033525 0,05828923 ! hemopoiesis GO:0030097 104 100 1,000 0,033525 0,05823429 ! translational initiation GO:0006413 12 12 0,000 0,03435839 0,05962572 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,03435839 0,05956963 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,03435839 0,05951365 ! initiation of viral infection GO:0019059 12 12 0,000 0,03435839 0,05945777 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,03435839 0,05940199 ! iron ion transport GO:0006826 13 12 0,000 0,03435839 0,05934632 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,03435839 0,05929075 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,03435839 0,05923529 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,03435839 0,05917993 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,03435839 0,05912467 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,03435839 0,05906951 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,03435839 0,05901446 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,03435839 0,05895952 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,03435839 0,05890467 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,03435839 0,05884993 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,03435839 0,05879528 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,03435839 0,05874074 ! actomyosin structure organization GO:0031032 12 12 0,000 0,03435839 0,0586863 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,03435839 0,05863196 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,03435839 0,05857772 ! retinoid metabolic process GO:0001523 12 12 0,000 0,03435839 0,05852359 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,03435839 0,05846955 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,03435839 0,05841561 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,03435839 0,05836177 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,03435839 0,05830803 ! acute-phase response GO:0006953 12 12 0,000 0,03435839 0,05825439 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,03435839 0,05820085 ! vacuolar transport GO:0007034 12 12 0,000 0,03435839 0,0581474 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,03435839 0,05809405 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,03435839 0,05804081 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,03435839 0,05798766 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,03435839 0,0579346 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,03435839 0,05788165 ! male gonad development GO:0008584 12 12 0,000 0,03435839 0,05782879 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,03435839 0,05777602 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,03435839 0,05772335 ! renal system process GO:0003014 12 12 0,000 0,03435839 0,05767078 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,03435839 0,05761831 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,03435839 0,05756593 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,03435839 0,05751364 ! pallium development GO:0021543 13 12 0,000 0,03435839 0,05746145 ! cell fate determination GO:0001709 12 12 0,000 0,03435839 0,05740936 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,03435839 0,05735735 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,03435839 0,05730545 ! somitogenesis GO:0001756 13 12 0,000 0,03435839 0,05725363 ! G1 phase GO:0051318 13 12 0,000 0,03435839 0,05720191 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,03435839 0,05715029 ! detection of light stimulus GO:0009583 13 12 0,000 0,03435839 0,05709876 ! synaptogenesis GO:0007416 12 12 0,000 0,03435839 0,05704732 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,03435839 0,05699597 ! hormone transport GO:0009914 12 12 0,000 0,03435839 0,05694471 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,03435839 0,05689355 ! heme biosynthetic process GO:0006783 12 12 0,000 0,03435839 0,05684248 ! spermatid differentiation GO:0048515 13 12 0,000 0,03435839 0,0567915 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,03435839 0,05674061 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,03435839 0,05668981 ! neural tube closure GO:0001843 13 12 0,000 0,03435839 0,05663911 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,03435839 0,05658849 ! negative regulation of translation GO:0017148 12 12 0,000 0,03435839 0,05653796 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,03435839 0,05648753 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,0371704 0,06105619 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,0371704 0,06100182 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,0371704 0,06094754 ! phenol metabolic process GO:0018958 13 13 0,000 0,0371704 0,06089337 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,0371704 0,06083929 ! gluconeogenesis GO:0006094 13 13 0,000 0,0371704 0,06078531 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,0371704 0,06073142 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,0371704 0,06067763 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,0371704 0,06062393 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,0371704 0,06057033 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,0371704 0,06051682 ! regeneration GO:0031099 13 13 0,000 0,0371704 0,06046341 ! keratinization GO:0031424 13 13 0,000 0,0371704 0,06041009 ! post-embryonic development GO:0009791 14 13 0,000 0,0371704 0,06035686 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,0371704 0,06030373 ! patterning of blood vessels GO:0001569 13 13 0,000 0,0371704 0,06025069 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,0371704 0,06019775 ! regulation of innate immune response GO:0045088 13 13 0,000 0,0371704 0,0601449 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,0371704 0,06009214 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,0371704 0,06003947 ! autophagy GO:0006914 13 13 0,000 0,0371704 0,0599869 ! receptor metabolic process GO:0043112 14 13 0,000 0,0371704 0,05993442 ! actin filament bundle formation GO:0051017 13 13 0,000 0,0371704 0,05988203 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,0371704 0,05982973 ! ureteric bud development GO:0001657 13 13 0,000 0,0371704 0,05977752 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,0371704 0,05972541 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,0371704 0,05967338 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,0371704 0,05962144 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,0371704 0,0595696 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,0371704 0,05951785 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,0371704 0,05946618 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,0371704 0,05941461 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,0371704 0,05936312 ! vasodilation GO:0042311 14 13 0,000 0,0371704 0,05931172 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,0371704 0,05926042 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,0371704 0,0592092 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,0371704 0,05915807 GO:0006664|glycolipid metabolic process, ! neural crest cell migration GO:0001755 14 13 0,000 0,0371704 0,05910702 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,0371704 0,05905607 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,0371704 0,0590052 ! immunoglobulin production GO:0002377 13 13 0,000 0,0371704 0,05895442 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,0371704 0,05890373 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,0371704 0,05885313 ! cell-cell junction organization GO:0045216 13 13 0,000 0,0371704 0,05880261 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,0371704 0,05875218 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,0371704 0,05870183 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,0371704 0,05865158 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,0371704 0,0586014 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,0371704 0,05855132 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,0371704 0,05850132 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,0371704 0,0584514 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,0371704 0,05840157 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,0371704 0,05835182 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,0371704 0,05830216 ! blastocyst development GO:0001824 13 13 0,000 0,0371704 0,05825259 ! telomere organization GO:0032200 13 13 0,000 0,0371704 0,05820309 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,0371704 0,05815368 ! regulation of amine transport GO:0051952 13 13 0,000 0,0371704 0,05810436 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,0371704 0,05805512 ! neuron fate commitment GO:0048663 14 14 0,000 0,03997462 0,06238207 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,03997462 0,06232929 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,03997462 0,0622766 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,03997462 0,062224 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,03997462 0,06217149 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,03997462 0,06211907 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,03997462 0,06206674 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,03997462 0,0620145 ! protein amino acid acylation GO:0043543 14 14 0,000 0,03997462 0,06196234 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,03997462 0,06191027 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,03997462 0,06185829 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,03997462 0,06180639 ! vesicle docking GO:0048278 14 14 0,000 0,03997462 0,06175459 ! superoxide metabolic process GO:0006801 15 14 0,000 0,03997462 0,06170287 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,03997462 0,06165123 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,03997462 0,06159968 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,03997462 0,06154822 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,03997462 0,06149685 ! hair cycle GO:0042633 14 14 0,000 0,03997462 0,06144556 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,03997462 0,06139435 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,03997462 0,06134323 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,03997462 0,0612922 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,03997462 0,06124125 ! lysosome organization GO:0007040 14 14 0,000 0,03997462 0,06119038 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,03997462 0,0611396 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,03997462 0,06108891 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,03997462 0,06103829 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,03997462 0,06098777 ! primary neural tube formation GO:0014020 15 14 0,000 0,03997462 0,06093732 ! peptide cross-linking GO:0018149 14 14 0,000 0,03997462 0,06088696 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,03997462 0,06083668 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,03997462 0,06078649 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,03997462 0,06073637 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,03997462 0,06068634 ! formation of primary germ layer GO:0001704 14 14 0,000 0,03997462 0,0606364 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,03997462 0,06058653 ! collagen fibril organization GO:0030199 14 14 0,000 0,03997462 0,06053675 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,03997462 0,06048705 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,03997462 0,06043743 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,03997462 0,06038789 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,03997462 0,06033843 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,03997462 0,06028905 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,03997462 0,06023976 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,03997462 0,06019054 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,03997462 0,06014141 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,03997462 0,06009235 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,04277108 0,06424377 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,04277108 0,06419145 ! positive regulation of ossification GO:0045778 15 15 0,000 0,04277108 0,06413922 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,04277108 0,06408707 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,04277108 0,06403501 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,04277108 0,06398304 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,04277108 0,06393114 ! response to vitamin GO:0033273 15 15 0,000 0,04277108 0,06387934 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,04277108 0,06382761 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,04277108 0,06377597 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,04277108 0,06372441 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,04277108 0,06367294 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,04277108 0,06362155 ! ovarian follicle development GO:0001541 15 15 0,000 0,04277108 0,06357024 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,04277108 0,06351902 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,04277108 0,06346787 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,04277108 0,06341681 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,04277108 0,06336584 ! heme metabolic process GO:0042168 15 15 0,000 0,04277108 0,06331494 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,04277108 0,06326413 ! chromosome condensation GO:0030261 15 15 0,000 0,04277108 0,06321339 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,04277108 0,06316274 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,04277108 0,06311217 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,04277108 0,06306168 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,04277108 0,06301127 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,04277108 0,06296094 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,04277108 0,06291069 ! phospholipid transport GO:0015914 15 15 0,000 0,04277108 0,06286053 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,04277108 0,06281044 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,04277108 0,06276043 ! glutathione metabolic process GO:0006749 16 15 0,000 0,04277108 0,0627105 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,04277108 0,06266065 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,04277108 0,06261088 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,04277108 0,06256119 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,04277108 0,06251158 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,04277108 0,06246204 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,04277108 0,06241259 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,04277108 0,06236321 ! protein homooligomerization GO:0051260 15 15 0,000 0,04277108 0,06231391 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,04277108 0,06226469 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,0455598 0,06627207 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,0455598 0,06621981 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,0455598 0,06616762 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,0455598 0,06611552 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,0455598 0,06606351 ! learning GO:0007612 16 16 0,000 0,0455598 0,06601157 ! circadian rhythm GO:0007623 16 16 0,000 0,0455598 0,06595971 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,0455598 0,06590794 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,0455598 0,06585625 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,0455598 0,06580464 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,0455598 0,06575311 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,0455598 0,06570166 ! vesicle targeting GO:0006903 17 16 0,000 0,0455598 0,06565029 ! segmentation GO:0035282 17 16 0,000 0,0455598 0,065599 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,0455598 0,06554779 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,0455598 0,06549666 ! iron ion homeostasis GO:0055072 16 16 0,000 0,0455598 0,06544561 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,0455598 0,06539464 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,0455598 0,06534375 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,0455598 0,06529294 ! cell fate specification GO:0001708 16 16 0,000 0,0455598 0,0652422 ! pentose metabolic process GO:0019321 16 16 0,000 0,0455598 0,06519155 ! fatty acid transport GO:0015908 16 16 0,000 0,0455598 0,06514097 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,0455598 0,06509048 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,0455598 0,06504006 ! cofactor catabolic process GO:0051187 16 16 0,000 0,0455598 0,06498972 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,0455598 0,06493946 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,0455598 0,06488927 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,0455598 0,06483916 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,0455598 0,06478913 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,0455598 0,06473918 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,0455598 0,0646893 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,0455598 0,0646395 ! regulation of coagulation GO:0050818 17 16 0,000 0,0455598 0,06458978 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,04834081 0,06847971 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,04834081 0,06842712 ! positive regulation of cell adhesion GO:0045785 17 17 0,000 0,04834081 0,0683746 ! myelination GO:0042552 17 17 0,000 0,04834081 0,06832217 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,04834081 0,06826981 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,04834081 0,06821754 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,04834081 0,06816534 ! leukocyte adhesion GO:0007159 17 17 0,000 0,04834081 0,06811323 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,04834081 0,06806119 ! sensory perception of smell GO:0007608 17 17 0,000 0,04834081 0,06800924 ! glucose transport GO:0015758 17 17 0,000 0,04834081 0,06795736 ! cell junction assembly GO:0034329 18 17 0,000 0,04834081 0,06790557 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,04834081 0,06785385 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,04834081 0,06780221 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,04834081 0,06775065 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,04834081 0,06769917 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,04834081 0,06764776 ! neural crest cell development GO:0014032 19 17 0,000 0,04834081 0,06759644 GO:0014033|neural crest cell differentiation, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,04834081 0,06754519 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,04834081 0,06749402 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,04834081 0,06744293 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,04834081 0,06739191 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,04834081 0,06734097 ! pigmentation GO:0043473 17 17 0,000 0,04834081 0,06729011 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,04834081 0,06723932 ! adult locomotory behavior GO:0008344 17 17 0,000 0,04834081 0,06718862 ! embryonic organ development GO:0048568 17 17 0,000 0,04834081 0,06713798 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,04834081 0,06708743 ! liver development GO:0001889 17 17 0,000 0,04834081 0,06703695 ! gene silencing GO:0016458 17 17 0,000 0,04834081 0,06698654 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,05111411 0,07077634 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,05111411 0,0707232 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,05111411 0,07067014 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,05111411 0,07061717 ! meiosis I GO:0007127 18 18 0,000 0,05111411 0,07056427 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,05111411 0,07051145 ! membrane docking GO:0022406 18 18 0,000 0,05111411 0,07045872 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,05111411 0,07040606 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,05111411 0,07035347 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,05111411 0,07030097 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,05111411 0,07024855 ! hexose transport GO:0008645 18 18 0,000 0,05111411 0,0701962 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,05111411 0,07014393 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,05111411 0,07009174 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,05111411 0,07003963 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,05111411 0,0699876 ! ceramide metabolic process GO:0006672 18 18 0,000 0,05111411 0,06993564 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,05111411 0,06988376 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,05111411 0,06983195 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,05111411 0,06978022 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,05111411 0,06972857 ! ensheathment of neurons GO:0007272 18 18 0,000 0,05111411 0,069677 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,05111411 0,0696255 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,05111411 0,06957408 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,05111411 0,06952273 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,05111411 0,06947146 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,05111411 0,06942027 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,05387973 0,0731225 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,05387973 0,07306869 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,05387973 0,07301496 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,05387973 0,07296131 ! feeding behavior GO:0007631 19 19 0,000 0,05387973 0,07290775 ! peroxisome organization GO:0007031 19 19 0,000 0,05387973 0,07285426 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,05387973 0,07280084 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,05387973 0,07274751 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,05387973 0,07269425 ! metanephros development GO:0001656 19 19 0,000 0,05387973 0,07264108 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,05387973 0,07258797 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,05387973 0,07253495 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,05387973 0,07248201 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,05387973 0,07242914 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,05387973 0,07237635 ! peripheral nervous system development GO:0007422 19 19 0,000 0,05387973 0,07232363 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,05387973 0,072271 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,05387973 0,07221844 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,05387973 0,07216595 ! eye morphogenesis GO:0048592 19 19 0,000 0,05387973 0,07211354 ! placenta development GO:0001890 19 19 0,000 0,05387973 0,07206121 ! response to heat GO:0009408 19 19 0,000 0,05387973 0,07200896 ! vesicle localization GO:0051648 20 19 0,000 0,05387973 0,07195678 ! regulation of muscle development GO:0048634 21 20 0,000 0,0566377 0,07558529 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,0566377 0,07553059 ! negative regulation of binding GO:0051100 21 20 0,000 0,0566377 0,07547598 ! organic ether metabolic process GO:0018904 20 20 0,000 0,0566377 0,07542145 GO:0006662|glycerol ether metabolic process, ! neural tube development GO:0021915 21 20 0,000 0,0566377 0,07536699 ! nucleus organization GO:0006997 20 20 0,000 0,0566377 0,07531261 ! phagocytosis GO:0006909 21 20 0,000 0,0566377 0,07525831 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,0566377 0,07520409 ! protein targeting to membrane GO:0006612 22 20 0,000 0,0566377 0,07514995 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,0566377 0,07509589 ! chromatin remodeling GO:0006338 20 20 0,000 0,0566377 0,0750419 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,0566377 0,07498799 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,0566377 0,07493416 ! lipid oxidation GO:0034440 20 20 0,000 0,0566377 0,0748804 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,0566377 0,07482672 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,0566377 0,07477312 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,0566377 0,0747196 ! RNA modification GO:0009451 20 20 0,000 0,0566377 0,07466615 ! single fertilization GO:0007338 21 20 0,000 0,0566377 0,07461278 ! regulation of B cell activation GO:0050864 20 20 0,000 0,0566377 0,07455949 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,05938803 0,07812429 ! mRNA catabolic process GO:0006402 21 21 0,000 0,05938803 0,07806857 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,05938803 0,07801293 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,05938803 0,07795736 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,05938803 0,07790188 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,05938803 0,07784647 ! Notch signaling pathway GO:0007219 22 21 0,000 0,05938803 0,07779114 ! ear morphogenesis GO:0042471 21 21 0,000 0,05938803 0,07773589 ! organic anion transport GO:0015711 21 21 0,000 0,05938803 0,07768072 ! cholesterol transport GO:0030301 21 21 0,000 0,05938803 0,07762563 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,05938803 0,07757061 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,05938803 0,07751568 GO:0032313|regulation of Rab GTPase activity, ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,05938803 0,07746082 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,05938803 0,07740604 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,05938803 0,07735133 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,05938803 0,07729671 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,05938803 0,07724216 ! regulation of proteolysis GO:0030162 21 21 0,000 0,05938803 0,07718768 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,05938803 0,07713329 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,05938803 0,07707897 ! positive regulation of transcription factor activity GO:0051091 22 22 0,000 0,06213074 0,08058195 GO:0090047|positive regulation of transcription regulator activity, ! RNA export from nucleus GO:0006405 22 22 0,000 0,06213074 0,08052528 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,06213074 0,08046869 ! sister chromatid segregation GO:0000819 22 22 0,000 0,06213074 0,08041218 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,06213074 0,08035575 ! regulation of ion transport GO:0043269 22 22 0,000 0,06213074 0,0802994 ! odontogenesis GO:0042476 22 22 0,000 0,06213074 0,08024313 ! cell junction organization GO:0034330 23 22 0,000 0,06213074 0,08018694 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,06213074 0,08013082 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,06213074 0,08007479 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,06213074 0,08001883 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,06213074 0,07996295 ! ovulation cycle process GO:0022602 22 22 0,000 0,06213074 0,07990715 ! spindle organization GO:0007051 22 22 0,000 0,06213074 0,07985143 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,06213074 0,07979578 ! cell chemotaxis GO:0060326 23 22 0,000 0,06213074 0,07974021 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,06213074 0,07968472 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,06213074 0,07962931 ! male sex differentiation GO:0046661 22 22 0,000 0,06213074 0,07957397 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,06213074 0,07951871 ! biopolymer methylation GO:0043414 22 22 0,000 0,06213074 0,07946353 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,06213074 0,07940842 ! detection of external stimulus GO:0009581 23 22 0,000 0,06213074 0,07935339 ! neuron migration GO:0001764 22 22 0,000 0,06213074 0,07929844 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,06213074 0,07924356 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,06213074 0,07918876 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,06213074 0,07913403 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,06213074 0,07907938 ! aerobic respiration GO:0009060 22 22 0,000 0,06213074 0,07902481 ! cytokine production GO:0001816 22 22 0,000 0,06213074 0,07897031 ! cytokinesis GO:0000910 23 22 0,000 0,06213074 0,07891588 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,06213074 0,07886153 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,06486585 0,0822765 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,06486585 0,08221991 ! viral infectious cycle GO:0019058 23 23 0,000 0,06486585 0,08216341 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,06486585 0,08210697 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,06486585 0,08205062 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,06486585 0,08199434 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,06486585 0,08193815 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,06486585 0,08188202 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,06486585 0,08182598 ! endocrine system development GO:0035270 23 23 0,000 0,06486585 0,08177001 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,06486585 0,08171412 ! positive regulation of growth GO:0045927 23 23 0,000 0,06486585 0,0816583 ! female gonad development GO:0008585 23 23 0,000 0,06486585 0,08160256 ! lipid homeostasis GO:0055088 23 23 0,000 0,06486585 0,0815469 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,06486585 0,08149131 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,06486585 0,0814358 ! cell projection assembly GO:0030031 25 23 0,000 0,06486585 0,08138036 ! regulation of action potential GO:0001508 24 24 0,000 0,06759338 0,08474462 ! gliogenesis GO:0042063 24 24 0,000 0,06759338 0,08468701 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,06759338 0,08462948 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,06759338 0,08457203 ! glucose homeostasis GO:0042593 24 24 0,000 0,06759338 0,08451465 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,06759338 0,08445735 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,06759338 0,08440013 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,06759338 0,08434299 ! ovulation cycle GO:0042698 24 24 0,000 0,06759338 0,08428592 ! fertilization GO:0009566 25 24 0,000 0,06759338 0,08422894 ! maintenance of protein location GO:0045185 25 24 0,000 0,06759338 0,08417202 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,06759338 0,08411519 ! androgen receptor signaling pathway GO:0030521 24 24 0,000 0,06759338 0,08405843 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,06759338 0,08400175 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,07031335 0,08732312 ! negative regulation of secretion GO:0051048 26 25 0,000 0,07031335 0,08726431 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,07031335 0,08720559 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,07031335 0,08714694 ! cellular component disassembly GO:0022411 26 25 0,000 0,07031335 0,08708838 ! endosome transport GO:0016197 25 25 0,000 0,07031335 0,08702989 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,07031335 0,08697148 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,07031335 0,08691315 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,07031335 0,0868549 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,07031335 0,08679672 ! excretion GO:0007588 25 25 0,000 0,07031335 0,08673862 ! positive regulation of DNA binding GO:0043388 26 25 0,000 0,07031335 0,08668061 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,07031335 0,08662266 ! gastrulation GO:0007369 25 25 0,000 0,07031335 0,0865648 ! heart morphogenesis GO:0003007 25 25 0,000 0,07031335 0,08650701 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,07031335 0,0864493 ! regulation of endocytosis GO:0030100 25 25 0,000 0,07031335 0,08639167 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,07031335 0,08633411 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,07031335 0,08627663 ! positive regulation of binding GO:0051099 27 26 0,000 0,07302578 0,08954526 ! positive regulation of defense response GO:0031349 26 26 0,000 0,07302578 0,08948572 ! glycolysis GO:0006096 26 26 0,000 0,07302578 0,08942626 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,07302578 0,08936688 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,07302578 0,08930758 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,07302578 0,08924836 ! cellular defense response GO:0006968 26 26 0,000 0,07302578 0,08918921 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,07302578 0,08913015 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,07302578 0,08907116 ! regulation of protein secretion GO:0050708 26 26 0,000 0,07302578 0,08901225 ! germ cell development GO:0007281 27 26 0,000 0,07302578 0,08895342 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,07302578 0,08889466 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,07302578 0,08883599 ! response to insulin stimulus GO:0032868 28 26 0,000 0,07302578 0,08877739 ! maintenance of location in cell GO:0051651 27 26 0,000 0,07302578 0,08871887 ! synapse organization GO:0050808 26 26 0,000 0,07302578 0,08866042 ! chloride transport GO:0006821 27 27 0,000 0,0757307 0,09188392 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,0757307 0,09182347 ! learning or memory GO:0007611 28 27 0,000 0,0757307 0,0917631 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,0757307 0,09170281 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,0757307 0,0916426 ! peptide metabolic process GO:0006518 29 27 0,000 0,0757307 0,09158247 ! mesenchymal cell development GO:0014031 29 27 0,000 0,0757307 0,09152241 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! inner ear development GO:0048839 27 27 0,000 0,0757307 0,09146244 ! defense response to bacterium GO:0042742 27 27 0,000 0,0757307 0,09140254 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,0757307 0,09134272 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,0757307 0,09128298 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,07842811 0,09447256 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,07842811 0,09441085 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,07842811 0,09434923 ! carbohydrate transport GO:0008643 28 28 0,000 0,07842811 0,09428768 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,07842811 0,09422621 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,07842811 0,09416483 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,07842811 0,09410352 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,07842811 0,0940423 ! histone modification GO:0016570 28 28 0,000 0,07842811 0,09398115 ! developmental growth GO:0048589 28 28 0,000 0,07842811 0,09392009 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,07842811 0,0938591 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,08111805 0,09701529 ! viral reproductive process GO:0022415 29 29 0,000 0,08111805 0,09695238 ! leukocyte migration GO:0050900 30 29 0,000 0,08111805 0,09688954 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,08111805 0,09682679 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,08111805 0,09676412 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,08111805 0,09670153 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,08111805 0,09663902 ! tRNA processing GO:0008033 29 29 0,000 0,08111805 0,09657659 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,08111805 0,09651424 ! covalent chromatin modification GO:0016569 29 29 0,000 0,08111805 0,09645198 ! adult behavior GO:0030534 30 29 0,000 0,08111805 0,09638979 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,08111805 0,09632768 ! transition metal ion transport GO:0000041 31 30 0,000 0,08380052 0,09944905 ! RNA catabolic process GO:0006401 30 30 0,000 0,08380052 0,09938505 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,08380052 0,09932114 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,08380052 0,09925731 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,08380052 0,09919356 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,08380052 0,09912989 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,08380052 0,0990663 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,08380052 0,0990028 ! response to temperature stimulus GO:0009266 30 30 0,000 0,08380052 0,09893938 ! regulation of ossification GO:0030278 30 30 0,000 0,08380052 0,09887604 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,08380052 0,09881277 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,08380052 0,0987496 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,08380052 0,0986865 ! vesicle organization GO:0016050 30 30 0,000 0,08380052 0,09862348 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,08380052 0,09856054 ! establishment of organelle localization GO:0051656 31 30 0,000 0,08380052 0,09849768 ! regulation of translational initiation GO:0006446 31 31 0,000 0,08647556 0,10157709 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,08647556 0,10151239 ! membrane fusion GO:0006944 31 31 0,000 0,08647556 0,10144778 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,08647556 0,10138324 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,08647556 0,10131879 ! ion transmembrane transport GO:0034220 31 31 0,000 0,08647556 0,10125442 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,08647556 0,10119013 ! digestion GO:0007586 31 31 0,000 0,08647556 0,10112592 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,08647556 0,1010618 ! regulation of heart contraction GO:0008016 31 31 0,000 0,08647556 0,10099775 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,08647556 0,10093379 ! camera-type eye development GO:0043010 31 31 0,000 0,08647556 0,10086991 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,08647556 0,10080611 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,08647556 0,10074239 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,08647556 0,10067875 ! cell redox homeostasis GO:0045454 32 32 0,000 0,08914317 0,10371898 ! muscle fiber development GO:0048747 32 32 0,000 0,08914317 0,10365355 ! glucose catabolic process GO:0006007 32 32 0,000 0,08914317 0,10358819 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,08914317 0,10352292 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,08914317 0,10345773 ! cell maturation GO:0048469 32 32 0,000 0,08914317 0,10339262 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,08914317 0,10332759 ! nuclear export GO:0051168 32 32 0,000 0,08914317 0,10326265 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,08914317 0,10319778 ! kidney development GO:0001822 32 32 0,000 0,08914317 0,103133 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,08914317 0,1030683 ! maintenance of location GO:0051235 33 32 0,000 0,08914317 0,10300368 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,09180339 0,10601105 ! amino acid transport GO:0006865 33 33 0,000 0,09180339 0,10594467 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,09180339 0,10587837 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,09180339 0,10581216 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,09180339 0,10574603 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,09180339 0,10567998 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,09180339 0,10561401 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,09180339 0,10554812 ! regulation of actin filament length GO:0030832 34 34 0,000 0,09445622 0,10853043 ! regulation of angiogenesis GO:0045765 35 34 0,000 0,09445622 0,10846281 ! response to metal ion GO:0010038 34 34 0,000 0,09445622 0,10839527 ! ear development GO:0043583 34 34 0,000 0,09445622 0,10832782 ! muscle cell differentiation GO:0042692 35 34 0,000 0,09445622 0,10826045 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,09445622 0,10819317 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,09445622 0,10812597 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,09445622 0,10805885 ! secondary metabolic process GO:0019748 34 34 0,000 0,09445622 0,10799182 ! response to peptide hormone stimulus GO:0043434 36 34 0,000 0,09445622 0,10792487 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,09445622 0,107858 ! viral reproduction GO:0016032 34 34 0,000 0,09445622 0,10779121 ! detection of stimulus GO:0051606 36 34 0,000 0,09445622 0,10772451 ! acute inflammatory response GO:0002526 35 35 0,000 0,09710169 0,1106731 ! regulation of cellular component size GO:0032535 35 35 0,000 0,09710169 0,1106047 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,09710169 0,11053638 ! mesoderm development GO:0007498 35 35 0,000 0,09710169 0,11046815 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,09710169 0,1104 GO:0048609|reproductive process in a multicellular organism, ! inorganic anion transport GO:0015698 35 35 0,000 0,09710169 0,11033194 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,09710169 0,11026396 ! hydrogen transport GO:0006818 36 36 0,000 0,09973981 0,11318995 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,09973981 0,11312029 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,09973981 0,11305072 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,09973981 0,11298124 ! regulation of mitosis GO:0007088 37 36 0,000 0,09973981 0,11291184 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,09973981 0,11284252 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,09973981 0,11277329 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,09973981 0,11270415 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,09973981 0,11263509 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,09973981 0,11256612 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,09973981 0,11249723 ! gonad development GO:0008406 36 36 0,000 0,09973981 0,11242842 ! activation of immune response GO:0002253 36 36 0,000 0,09973981 0,1123597 ! coagulation GO:0050817 39 36 0,000 0,09973981 0,11229106 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,10237061 0,11518256 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 0,000 0,10237061 0,11511229 GO:0090046|regulation of transcription regulator activity, ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,10237061 0,1150421 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,10237061 0,11497199 ! eye development GO:0001654 37 37 0,000 0,10237061 0,11490197 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,10237061 0,11483204 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,10237061 0,11476219 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,10237061 0,11469242 ! positive regulation of secretion GO:0051047 39 38 0,000 0,10499411 0,11756023 ! neurotransmitter transport GO:0006836 40 38 0,000 0,10499411 0,11748885 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,10499411 0,11741756 ! exocytosis GO:0006887 40 38 0,000 0,10499411 0,11734636 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,10499411 0,11727524 ! chromosome segregation GO:0007059 38 38 0,000 0,10499411 0,1172042 ! hexose catabolic process GO:0019320 38 38 0,000 0,10499411 0,11713326 ! RNA elongation GO:0006354 38 38 0,000 0,10499411 0,1170624 ! axon guidance GO:0007411 39 38 0,000 0,10499411 0,11699162 ! regulation of neurological system process GO:0031644 38 38 0,000 0,10499411 0,11692093 ! steroid hormone receptor signaling pathway GO:0030518 38 38 0,000 0,10499411 0,11685033 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,10761032 0,11968969 ! hemostasis GO:0007599 42 39 0,000 0,10761032 0,1196175 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,10761032 0,1195454 ! activation of MAPK activity GO:0000187 39 39 0,000 0,10761032 0,11947339 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,10761032 0,11940146 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,10761032 0,11932961 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,10761032 0,11925786 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,10761032 0,11918619 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,10761032 0,11911461 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,10761032 0,11904311 ! developmental maturation GO:0021700 39 39 0,000 0,10761032 0,1189717 ! limb development GO:0060173 39 39 0,000 0,10761032 0,11890037 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,11021926 0,12171007 ! DNA catabolic process GO:0006308 41 40 0,000 0,11021926 0,12163719 ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,11021926 0,1215644 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 0,000 0,11021926 0,12149169 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,11021926 0,12141907 ! organelle localization GO:0051640 41 40 0,000 0,11021926 0,12134654 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,11282096 0,12413674 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,11282096 0,12406267 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,11282096 0,12398869 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,11282096 0,1239148 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,11282096 0,123841 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,11282096 0,12376728 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,11282096 0,12369366 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,11541543 0,12646293 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,11541543 0,12638779 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,11541543 0,12631273 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,11541543 0,12623777 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,11541543 0,1261629 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! forebrain development GO:0030900 43 42 0,000 0,11541543 0,12608811 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,11541543 0,12601341 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,11541543 0,12593881 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,11800269 0,12868578 ! alcohol catabolic process GO:0046164 43 43 0,000 0,11800269 0,12860968 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,11800269 0,12853367 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,11800269 0,12845775 ! humoral immune response GO:0006959 44 44 0,000 0,12058277 0,13118892 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,12058277 0,13111153 ! mRNA transport GO:0051028 44 44 0,000 0,12058277 0,13103422 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,12058277 0,130957 ! vitamin metabolic process GO:0006766 44 44 0,000 0,12058277 0,13087988 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,12058277 0,13080285 ! amine biosynthetic process GO:0009309 46 45 0,000 0,12315567 0,13351523 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,12315567 0,13343674 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,12315567 0,13335834 ! regulation of DNA binding GO:0051101 47 45 0,000 0,12315567 0,13328003 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,12315567 0,13320181 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,12315567 0,13312369 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,12315567 0,13304566 ! protein processing GO:0016485 45 45 0,000 0,12315567 0,13296772 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,12572141 0,13565841 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,12572141 0,13557903 ! tube morphogenesis GO:0035239 47 46 0,000 0,12572141 0,13549975 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,12572141 0,13542055 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,12572141 0,13534145 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,12572141 0,13526244 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,12572141 0,13518353 ! regulation of membrane potential GO:0042391 46 46 0,000 0,12572141 0,1351047 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,12828003 0,13777395 ! regulation of blood pressure GO:0008217 48 47 0,000 0,12828003 0,1376937 ! amine transport GO:0015837 47 47 0,000 0,12828003 0,13761356 ! rhythmic process GO:0048511 47 47 0,000 0,12828003 0,1375335 ! calcium ion transport GO:0006816 48 48 0,000 0,13083153 0,1401875 ! actin filament organization GO:0007015 50 48 0,000 0,13083153 0,14010605 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,13083153 0,14002468 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,13083153 0,13994342 ! DNA recombination GO:0006310 48 48 0,000 0,13083153 0,13986224 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,13337593 0,14249962 ! divalent metal ion transport GO:0070838 49 49 0,000 0,13337593 0,14241706 ! skeletal muscle tissue development GO:0007519 50 49 0,000 0,13337593 0,14233459 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 0,000 0,13337593 0,14225222 ! response to bacterium GO:0009617 50 49 0,000 0,13337593 0,14216995 ! regulation of ligase activity GO:0051340 50 49 0,000 0,13337593 0,14208777 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,13337593 0,14200569 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,13337593 0,1419237 GO:0002696|positive regulation of leukocyte activation, ! chromatin assembly GO:0031497 50 50 0,000 0,13591326 0,14454018 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,13591326 0,14445683 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,13591326 0,14437357 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,13591326 0,1442904 ! transcription initiation GO:0006352 50 50 0,000 0,13591326 0,14420733 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,13844353 0,14680749 ! positive regulation of immune response GO:0050778 51 51 0,000 0,13844353 0,14672307 ! rRNA metabolic process GO:0016072 51 51 0,000 0,13844353 0,14663875 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,13844353 0,14655452 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,13844353 0,14647039 ! protein maturation GO:0051604 51 51 0,000 0,13844353 0,14638636 ! RNA localization GO:0006403 52 52 0,000 0,14096676 0,14896888 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,14096676 0,14888351 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,14096676 0,14879824 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,14096676 0,14871307 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,14096676 0,14862799 ! sodium ion transport GO:0006814 53 53 0,000 0,14348296 0,15119446 ! tRNA metabolic process GO:0006399 53 53 0,000 0,14348296 0,15110806 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,14348296 0,15102176 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,14348296 0,15093556 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,14348296 0,15084946 ! regulation of T cell activation GO:0050863 53 53 0,000 0,14348296 0,15076346 ! response to virus GO:0009615 54 54 0,000 0,14599217 0,15331257 ! hormone metabolic process GO:0042445 55 54 0,000 0,14599217 0,15322527 ! sulfur metabolic process GO:0006790 55 54 0,000 0,14599217 0,15313806 ! nucleosome organization GO:0034728 55 55 0,000 0,14849439 0,15567415 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,14849439 0,15558565 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,14849439 0,15549725 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,15098964 0,15802039 ! regulation of binding GO:0051098 60 57 0,000 0,15347795 0,16053341 ! ATP metabolic process GO:0046034 57 57 0,000 0,15347795 0,16044235 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,15347795 0,1603514 ! innate immune response GO:0045087 58 58 0,000 0,15595933 0,16285158 ! carboxylic acid transport GO:0046942 59 59 0,000 0,1584338 0,16534172 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,1584338 0,16524815 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,1584338 0,16515469 ! immune effector process GO:0002252 59 59 0,000 0,1584338 0,16506133 ! potassium ion transport GO:0006813 60 60 0,000 0,16090137 0,16753741 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,16090137 0,16744281 ! protein polymerization GO:0051258 65 60 0,000 0,16090137 0,16734832 ! cellular respiration GO:0045333 62 61 0,000 0,16336207 0,16981178 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,16336207 0,16971606 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,16336207 0,16962045 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,16336207 0,16952494 ! lipid transport GO:0006869 62 62 0,000 0,16581591 0,17197452 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,16581591 0,1718778 ! axonogenesis GO:0007409 66 62 0,000 0,16581591 0,17178118 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,16581591 0,17168468 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,16581591 0,17158828 ! regulation of secretion GO:0051046 65 63 0,000 0,16826292 0,17402276 ! glucose metabolic process GO:0006006 63 63 0,000 0,16826292 0,17392516 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,16826292 0,17382767 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,16826292 0,17373028 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,1707031 0,17615107 ! anion transport GO:0006820 65 65 0,000 0,17313649 0,17856214 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,17313649 0,17846227 ! regulation of hormone levels GO:0010817 66 65 0,000 0,17313649 0,17836252 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,17556308 0,18076132 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,17556308 0,18066039 ! DNA packaging GO:0006323 66 66 0,000 0,17556308 0,18055958 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,17556308 0,18045888 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 0,000 0,17798292 0,18284421 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 0,000 0,17798292 0,18274235 ! muscle contraction GO:0006936 67 67 0,000 0,17798292 0,1826406 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,180396 0,18501382 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,180396 0,18491092 ! regulation of translation GO:0006417 69 69 0,000 0,18280235 0,18727334 ! sensory perception of sound GO:0007605 71 69 0,000 0,18280235 0,1871693 GO:0050954|sensory perception of mechanical stimulus, ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,18280235 0,18706537 ! cell part morphogenesis GO:0032990 75 70 0,000 0,185202 0,1894158 ! wound healing GO:0042060 74 70 0,000 0,185202 0,18931075 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,185202 0,18920581 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,18759494 0,19154431 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,18759494 0,19143825 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,18759494 0,19133231 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,18759494 0,19122648 ! regulation of cell activation GO:0050865 71 71 0,000 0,18759494 0,19112077 ! secretion by cell GO:0032940 75 72 0,000 0,18998121 0,19344496 ! muscle system process GO:0003012 72 72 0,000 0,18998121 0,19333814 ! sensory organ development GO:0007423 72 72 0,000 0,18998121 0,19323144 ! regulation of cytokine production GO:0001817 72 72 0,000 0,18998121 0,19312486 ! electron transport chain GO:0022900 75 74 0,000 0,19473378 0,19784695 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,19473378 0,19773794 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,19710013 0,20003058 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,19710013 0,19992049 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,19945986 0,20220271 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,20181301 0,20447574 ! cell morphogenesis involved in differentiation GO:0000904 82 77 0,000 0,20181301 0,20436339 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,20415958 0,20662609 ! metal ion homeostasis GO:0055065 78 78 0,000 0,20415958 0,20651268 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,20883308 0,21112417 ! MAPKKK cascade GO:0000165 82 81 0,000 0,21116004 0,21335963 ! lipid catabolic process GO:0016042 82 81 0,000 0,21116004 0,21324272 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,21579448 0,21780351 ! ncRNA processing GO:0034470 83 83 0,000 0,21579448 0,2176843 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,21810198 0,21989166 ! hexose metabolic process GO:0019318 87 86 0,000 0,22269765 0,22440228 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,22726766 0,22888213 ! chemotaxis GO:0006935 90 89 0,000 0,22954308 0,23104746 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,22954308 0,23092134 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,23181213 0,23307679 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,23407483 0,23522351 ! visual perception GO:0007601 93 92 0,000 0,2363312 0,23736153 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,2363312 0,23723225 ! cofactor metabolic process GO:0051186 95 94 0,000 0,24082502 0,2416116 ! endocytosis GO:0006897 99 98 0,000 0,24973739 0,25041676 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,24973739 0,25028059 ! regulation of system process GO:0044057 98 98 0,000 0,24973739 0,25014457 ! anti-apoptosis GO:0006916 100 99 0,000 0,2519499 0,25222361 ! response to hormone stimulus GO:0009725 102 100 0,000 0,25415621 0,25429419 ! response to other organism GO:0051707 101 100 0,000 0,25415621 0,25415621