pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6466-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! positive regulation of epithelial cell proliferation GO:0050679 14 14 4,000 1,519E-07 2,799E-04 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 3,000 1,06E-06 9,766E-04 ! positive regulation of cell migration GO:0030335 36 36 5,000 1,149E-06 7,061E-04 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 4,000 1,463E-06 6,74E-04 ! cytokine-mediated signaling pathway GO:0019221 39 39 5,000 1,881E-06 6,933E-04 ! positive regulation of cell motion GO:0051272 39 39 5,000 1,881E-06 5,778E-04 ! gland development GO:0048732 51 49 5,000 7,461E-06 1,964E-03 ! regulation of epithelial cell proliferation GO:0050678 29 29 4,000 8,031E-06 1,85E-03 ! positive regulation of protein transport GO:0051222 29 29 4,000 8,031E-06 1,645E-03 ! hemoglobin biosynthetic process GO:0042541 5 5 2,000 9,107E-06 1,678E-03 ! prostate gland development GO:0030850 5 5 2,000 9,107E-06 1,526E-03 ! endocrine pancreas development GO:0031018 5 5 2,000 9,107E-06 1,399E-03 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 2,000 9,107E-06 1,291E-03 ! response to hypoxia GO:0001666 53 53 5,000 1,187E-05 1,563E-03 ! regulation of protein transport GO:0051223 53 53 5,000 1,187E-05 1,459E-03 GO:0070201|regulation of establishment of protein localization, ! response to oxygen levels GO:0070482 55 54 5,000 1,326E-05 1,527E-03 ! regulation of angiogenesis GO:0045765 35 34 4,000 1,811E-05 1,963E-03 ! regulation of protein localization GO:0032880 58 57 5,000 1,82E-05 1,863E-03 ! lung development GO:0030324 38 37 4,000 2,773E-05 2,69E-03 ! negative regulation of growth GO:0045926 37 37 4,000 2,773E-05 2,555E-03 ! regulation of endothelial cell proliferation GO:0001936 19 19 3,000 3,026E-05 2,655E-03 ! multicellular organismal metabolic process GO:0044236 19 19 3,000 3,026E-05 2,535E-03 ! regulation of chemokine production GO:0032642 7 7 2,000 3,142E-05 2,518E-03 ! hemoglobin metabolic process GO:0020027 7 7 2,000 3,142E-05 2,413E-03 ! cranial nerve development GO:0021545 7 7 2,000 3,142E-05 2,317E-03 ! urogenital system development GO:0001655 38 38 4,000 3,169E-05 2,246E-03 ! respiratory tube development GO:0030323 40 39 4,000 3,607E-05 2,462E-03 ! respiratory system development GO:0060541 40 39 4,000 3,607E-05 2,374E-03 ! positive regulation of leukocyte migration GO:0002687 8 8 2,000 4,992E-05 3,173E-03 ! positive regulation of translation GO:0045727 8 8 2,000 4,992E-05 3,067E-03 ! pancreas development GO:0031016 8 8 2,000 4,992E-05 2,968E-03 ! regulation of cell size GO:0008361 68 68 5,000 5,041E-05 2,903E-03 ! regulation of cell migration GO:0030334 71 71 5,000 6,444E-05 3,599E-03 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 2,000 7,435E-05 4,03E-03 ! pigmentation during development GO:0048066 9 9 2,000 7,435E-05 3,915E-03 ! regulation of leukocyte migration GO:0002685 9 9 2,000 7,435E-05 3,807E-03 ! regulation of intracellular protein transport GO:0033157 25 25 3,000 9,443E-05 4,704E-03 ! cell-substrate junction assembly GO:0007044 11 10 2,000 1,055E-04 5,115E-03 ! nerve development GO:0021675 10 10 2,000 1,055E-04 4,984E-03 ! positive regulation of MAP kinase activity GO:0043406 50 49 4,000 1,107E-04 5,1E-03 ! regulation of locomotion GO:0040012 79 79 5,000 1,176E-04 5,285E-03 ! regulation of cell motion GO:0051270 79 79 5,000 1,176E-04 5,159E-03 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 3,000 1,291E-04 5,532E-03 ! interphase of mitotic cell cycle GO:0051329 52 51 4,000 1,343E-04 5,625E-03 GO:0051325|interphase, ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 2,000 1,44E-04 5,897E-03 GO:0032388|positive regulation of intracellular transport, ! regulation of monooxygenase activity GO:0032768 11 11 2,000 1,44E-04 5,769E-03 ! regulation of cellular localization GO:0060341 86 85 5,000 1,766E-04 6,925E-03 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 5,000 1,884E-04 7,233E-03 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 2,000 1,906E-04 7,17E-03 ! heterophilic cell adhesion GO:0007157 12 12 2,000 1,906E-04 7,027E-03 ! collagen metabolic process GO:0032963 12 12 2,000 1,906E-04 6,889E-03 ! heart development GO:0007507 90 87 5,000 2,008E-04 7,116E-03 ! regulation of intracellular transport GO:0032386 31 31 3,000 2,246E-04 7,811E-03 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 2,000 2,461E-04 8,399E-03 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 2,000 2,461E-04 8,246E-03 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 2,000 2,461E-04 8,099E-03 ! positive regulation of locomotion GO:0040017 13 13 2,000 2,461E-04 7,957E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! negative regulation of cell growth GO:0030308 32 32 3,000 2,548E-04 8,097E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 3,000 2,548E-04 7,96E-03 ! negative regulation of cell size GO:0045792 33 33 3,000 2,878E-04 8,841E-03 ! regulation of behavior GO:0050795 14 14 2,000 3,11E-04 9,396E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 3,000 3,629E-04 0,01078637 ! positive regulation of phosphorylation GO:0042327 35 35 3,000 3,629E-04 0,01061516 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 2,000 3,86E-04 0,01111495 ! angiogenesis GO:0001525 65 64 4,000 3,947E-04 0,01119205 ! positive regulation of protein metabolic process GO:0051247 64 64 4,000 3,947E-04 0,01102247 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 3,000 4,052E-04 0,01114601 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of MAP kinase activity GO:0043405 67 66 4,000 4,557E-04 0,01235023 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 2,000 4,717E-04 0,01259908 ! positive regulation of catabolic process GO:0009896 16 16 2,000 4,717E-04 0,0124191 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 2,000 5,687E-04 0,01476304 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 2,000 5,687E-04 0,014558 ! cell junction assembly GO:0034329 18 17 2,000 5,687E-04 0,01435857 ! tissue remodeling GO:0048771 17 17 2,000 5,687E-04 0,01416454 ! embryonic skeletal system morphogenesis GO:0048704 17 17 2,000 5,687E-04 0,01397568 ! regulation of oxidoreductase activity GO:0051341 17 17 2,000 5,687E-04 0,01379179 ! positive regulation of protein secretion GO:0050714 17 17 2,000 5,687E-04 0,01361267 ! pigmentation GO:0043473 17 17 2,000 5,687E-04 0,01343815 ! embryonic organ development GO:0048568 17 17 2,000 5,687E-04 0,01326805 ! positive regulation of transport GO:0051050 71 70 4,000 5,986E-04 0,01379032 ! wound healing GO:0042060 74 70 4,000 5,986E-04 0,01362007 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 2,000 6,777E-04 0,01523098 ! regulation of JAK-STAT cascade GO:0046425 19 19 2,000 7,991E-04 0,0177429 ! dorsal/ventral pattern formation GO:0009953 19 19 2,000 7,991E-04 0,01753168 ! homeostasis of number of cells GO:0048872 44 43 3,000 8,059E-04 0,01747487 ! positive regulation of gene-specific transcription GO:0043193 20 20 2,000 9,334E-04 0,02000387 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 1,000 9,443E-04 0,02000416 ! neuron fate specification GO:0048665 5 5 1,000 9,443E-04 0,01977684 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 9,443E-04 0,01955463 ! forebrain regionalization GO:0021871 5 5 1,000 9,443E-04 0,01933735 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 1,000 9,443E-04 0,01912486 GO:0010469|regulation of receptor activity, ! mRNA stabilization GO:0048255 5 5 1,000 9,443E-04 0,01891698 GO:0043489|RNA stabilization, ! macrophage chemotaxis GO:0048246 6 5 1,000 9,443E-04 0,01871357 ! memory GO:0007613 5 5 1,000 9,443E-04 0,01851449 ! erythrocyte maturation GO:0043249 5 5 1,000 9,443E-04 0,0183196 ! heart looping GO:0001947 5 5 1,000 9,443E-04 0,01812877 ! melanocyte differentiation GO:0030318 5 5 1,000 9,443E-04 0,01794187 GO:0050931|pigment cell differentiation, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 1,000 9,443E-04 0,01775879 GO:0033135|regulation of peptidyl-serine phosphorylation, ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 9,443E-04 0,01757941 ! maintenance of protein location in nucleus GO:0051457 5 5 1,000 9,443E-04 0,01740362 ! substrate-bound cell migration, cell extension GO:0006930 5 5 1,000 9,443E-04 0,01723131 ! wound healing, spreading of epidermal cells GO:0035313 5 5 1,000 9,443E-04 0,01706237 ! activated T cell proliferation GO:0050798 5 5 1,000 9,443E-04 0,01689672 ! enucleate erythrocyte differentiation GO:0043353 6 5 1,000 9,443E-04 0,01673425 ! positive regulation of interleukin-6 production GO:0032755 5 5 1,000 9,443E-04 0,01657487 ! positive regulation of monooxygenase activity GO:0032770 5 5 1,000 9,443E-04 0,01641851 ! spinal cord motor neuron differentiation GO:0021522 5 5 1,000 9,443E-04 0,01626506 GO:0021517|ventral spinal cord development, ! regulation of hormone metabolic process GO:0032350 5 5 1,000 9,443E-04 0,01611446 ! peptidyl-lysine modification GO:0018205 5 5 1,000 9,443E-04 0,01596662 ! positive regulation of erythrocyte differentiation GO:0045648 5 5 1,000 9,443E-04 0,01582147 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 1,000 9,443E-04 0,01567894 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 1,000 9,443E-04 0,01553895 GO:0045622|regulation of T-helper cell differentiation, ! leukocyte mediated cytotoxicity GO:0001909 5 5 1,000 9,443E-04 0,01540143 ! myeloid cell homeostasis GO:0002262 5 5 1,000 9,443E-04 0,01526633 ! ectodermal gut morphogenesis GO:0048567 5 5 1,000 9,443E-04 0,01513358 GO:0007439|ectodermal gut development, ! embryonic gut development GO:0048566 5 5 1,000 9,443E-04 0,01500312 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 9,443E-04 0,01487489 ! Wnt receptor signaling pathway GO:0016055 46 45 3,000 9,587E-04 0,01497383 ! mammary gland development GO:0030879 23 21 2,000 1,081E-03 0,01674719 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 2,000 1,081E-03 0,01660763 ! tube development GO:0035295 83 81 4,000 1,166E-03 0,01775245 ! positive regulation of transcription factor activity GO:0051091 22 22 2,000 1,243E-03 0,01878145 GO:0090047|positive regulation of transcription regulator activity, ! cell junction organization GO:0034330 23 22 2,000 1,243E-03 0,01862876 ! embryonic skeletal system development GO:0048706 22 22 2,000 1,243E-03 0,01847853 ! cell chemotaxis GO:0060326 23 22 2,000 1,243E-03 0,0183307 GO:0030595|leukocyte chemotaxis, ! erythrocyte differentiation GO:0030218 23 22 2,000 1,243E-03 0,01818522 ! blood vessel morphogenesis GO:0048514 84 83 4,000 1,301E-03 0,01887757 ! cell cycle arrest GO:0007050 49 49 3,000 1,324E-03 0,01905659 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 1,000 1,407E-03 0,02010758 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 1,407E-03 0,0199529 GO:0018409|peptide or protein amino-terminal blocking, ! regulation of lipid kinase activity GO:0043550 6 6 1,000 1,407E-03 0,01980059 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 1,407E-03 0,01965059 GO:0050927|positive regulation of positive chemotaxis, ! regulation of chemokine biosynthetic process GO:0045073 6 6 1,000 1,407E-03 0,01950284 ! oligodendrocyte differentiation GO:0048709 6 6 1,000 1,407E-03 0,0193573 ! ER overload response GO:0006983 6 6 1,000 1,407E-03 0,01921391 ! focal adhesion formation GO:0048041 7 6 1,000 1,407E-03 0,01907263 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 1,407E-03 0,01893341 GO:0070667|negative regulation of mast cell proliferation, ! regulation of vascular permeability GO:0043114 6 6 1,000 1,407E-03 0,01879621 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 1,407E-03 0,01866099 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 1,000 1,407E-03 0,0185277 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 1,000 1,407E-03 0,01839629 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 1,407E-03 0,01826674 ! DNA unwinding during replication GO:0006268 6 6 1,000 1,407E-03 0,018139 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 1,407E-03 0,01801304 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 1,407E-03 0,01788881 ! erythrocyte development GO:0048821 6 6 1,000 1,407E-03 0,01776628 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 1,000 1,407E-03 0,01764543 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! regulation of T-helper 2 type immune response GO:0002828 6 6 1,000 1,407E-03 0,0175262 ! salivary gland morphogenesis GO:0007435 6 6 1,000 1,407E-03 0,01740857 ! serine family amino acid biosynthetic process GO:0009070 6 6 1,000 1,407E-03 0,01729252 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 1,407E-03 0,017178 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! localization within membrane GO:0051668 6 6 1,000 1,407E-03 0,01706498 ! viral infectious cycle GO:0019058 23 23 2,000 1,42E-03 0,01710124 ! endocrine system development GO:0035270 23 23 2,000 1,42E-03 0,01699019 ! cell projection assembly GO:0030031 25 23 2,000 1,42E-03 0,01688058 ! anterior/posterior pattern formation GO:0009952 51 50 3,000 1,428E-03 0,01687047 ! positive regulation of protein kinase activity GO:0045860 89 86 4,000 1,525E-03 0,01790389 ! glucose homeostasis GO:0042593 24 24 2,000 1,611E-03 0,01879261 GO:0033500|carbohydrate homeostasis, ! erythrocyte homeostasis GO:0034101 25 24 2,000 1,611E-03 0,01867442 ! androgen receptor signaling pathway GO:0030521 24 24 2,000 1,611E-03 0,0185577 ! positive regulation of transferase activity GO:0051347 91 88 4,000 1,69E-03 0,01934351 GO:0033674|positive regulation of kinase activity, ! chemotaxis GO:0006935 90 89 4,000 1,777E-03 0,02021434 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 4,000 1,777E-03 0,02009033 ! regulation of gene-specific transcription GO:0032583 25 25 2,000 1,818E-03 0,02042924 ! regulation of T cell proliferation GO:0042129 25 25 2,000 1,818E-03 0,02030543 ! positive regulation of DNA binding GO:0043388 26 25 2,000 1,818E-03 0,0201831 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 2,000 1,818E-03 0,02006225 ! JAK-STAT cascade GO:0007259 26 25 2,000 1,818E-03 0,01994283 ! positive regulation of cytokine production GO:0001819 25 25 2,000 1,818E-03 0,01982482 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 1,000 1,958E-03 0,02122507 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 1,000 1,958E-03 0,02110095 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 1,958E-03 0,02097827 ! digestive system development GO:0055123 7 7 1,000 1,958E-03 0,02085701 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! cell differentiation in spinal cord GO:0021515 7 7 1,000 1,958E-03 0,02073714 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 1,000 1,958E-03 0,02061864 ! regulation of mRNA processing GO:0050684 7 7 1,000 1,958E-03 0,02050149 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 1,958E-03 0,02038566 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 1,958E-03 0,02027114 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! autonomic nervous system development GO:0048483 7 7 1,000 1,958E-03 0,02015789 ! platelet activation GO:0030168 8 7 1,000 1,958E-03 0,0200459 ! regulation of macrophage differentiation GO:0045649 8 7 1,000 1,958E-03 0,01993515 ! positive regulation of acute inflammatory response GO:0002675 7 7 1,000 1,958E-03 0,01982562 ! regulation of mRNA stability GO:0043488 7 7 1,000 1,958E-03 0,01971728 ! cell killing GO:0001906 7 7 1,000 1,958E-03 0,01961012 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 1,000 1,958E-03 0,01950412 ! negative regulation of T cell activation GO:0050868 7 7 1,000 1,958E-03 0,01939926 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 4,000 1,961E-03 0,01932441 ! positive regulation of binding GO:0051099 27 26 2,000 2,041E-03 0,02000412 ! positive regulation of defense response GO:0031349 26 26 2,000 2,041E-03 0,01989827 ! regulation of T cell differentiation GO:0045580 26 26 2,000 2,041E-03 0,01979355 ! regulation of protein secretion GO:0050708 26 26 2,000 2,041E-03 0,01968991 ! blood vessel development GO:0001568 95 94 4,000 2,262E-03 0,02171535 ! vasculature development GO:0001944 97 96 4,000 2,481E-03 0,02369371 ! histone modification GO:0016570 28 28 2,000 2,535E-03 0,02408357 ! protein amino acid autophosphorylation GO:0046777 28 28 2,000 2,535E-03 0,02396007 ! regulation of mast cell proliferation GO:0070666 28 28 2,000 2,535E-03 0,02383782 ! positive regulation of cell killing GO:0031343 8 8 1,000 2,594E-03 0,02426572 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 2,594E-03 0,02414317 ! DNA duplex unwinding GO:0032508 8 8 1,000 2,594E-03 0,02402184 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 1,000 2,594E-03 0,02390174 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 2,594E-03 0,02378282 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 2,594E-03 0,02366508 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 1,000 2,594E-03 0,02354851 ! salivary gland development GO:0007431 8 8 1,000 2,594E-03 0,02343307 ! peptidyl-serine modification GO:0018209 8 8 1,000 2,594E-03 0,02331877 ! regulation of acute inflammatory response GO:0002673 8 8 1,000 2,594E-03 0,02320557 ! regulation of immunoglobulin production GO:0002637 8 8 1,000 2,594E-03 0,02309346 ! regulation of RNA stability GO:0043487 8 8 1,000 2,594E-03 0,02298244 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 2,594E-03 0,02287247 ! peptide hormone secretion GO:0030072 8 8 1,000 2,594E-03 0,02276356 ! peptidyl-amino acid modification GO:0018193 61 59 3,000 2,64E-03 0,02306212 ! posttranscriptional regulation of gene expression GO:0010608 98 98 4,000 2,715E-03 0,0236045 ! positive regulation of cell cycle GO:0045787 29 29 2,000 2,808E-03 0,02429444 ! viral reproductive process GO:0022415 29 29 2,000 2,808E-03 0,02418091 ! leukocyte migration GO:0050900 30 29 2,000 2,808E-03 0,02406845 ! branching morphogenesis of a tube GO:0048754 29 29 2,000 2,808E-03 0,02395702 ! regulation of lymphocyte proliferation GO:0050670 29 29 2,000 2,808E-03 0,02384662 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! covalent chromatin modification GO:0016569 29 29 2,000 2,808E-03 0,02373723 ! hemopoiesis GO:0030097 104 100 4,000 2,965E-03 0,02495085 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 3,000 2,983E-03 0,02498972 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 3,000 2,983E-03 0,02487664 ! positive regulation of response to external stimulus GO:0032103 30 30 2,000 3,098E-03 0,02571766 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 2,000 3,098E-03 0,02560233 ! skeletal system morphogenesis GO:0048705 31 30 2,000 3,098E-03 0,02548804 ! morphogenesis of an epithelium GO:0002009 63 62 3,000 3,165E-03 0,02592737 GO:0060429|epithelium development, ! positive regulation of cell size GO:0045793 9 9 1,000 3,314E-03 0,02702216 ! viral genome replication GO:0019079 9 9 1,000 3,314E-03 0,02690312 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 1,000 3,314E-03 0,02678512 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 1,000 3,314E-03 0,02666815 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 3,314E-03 0,02655221 ! substrate-bound cell migration GO:0006929 9 9 1,000 3,314E-03 0,02643726 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 1,000 3,314E-03 0,02632331 GO:0060675|ureteric bud morphogenesis, ! peptide secretion GO:0002790 9 9 1,000 3,314E-03 0,02621033 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 1,000 3,314E-03 0,02609832 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 3,314E-03 0,02598727 ! DNA replication initiation GO:0006270 9 9 1,000 3,314E-03 0,02587715 ! histone acetylation GO:0016573 9 9 1,000 3,314E-03 0,02576796 ! positive regulation of oxidoreductase activity GO:0051353 9 9 1,000 3,314E-03 0,02565969 ! positive regulation of cytokine secretion GO:0050715 9 9 1,000 3,314E-03 0,02555233 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 3,314E-03 0,02544586 ! collagen catabolic process GO:0030574 9 9 1,000 3,314E-03 0,02534028 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 1,000 3,314E-03 0,02523557 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 3,314E-03 0,02513172 ! defense response to virus GO:0051607 9 9 1,000 3,314E-03 0,02502872 ! regulation of myeloid cell differentiation GO:0045637 32 31 2,000 3,406E-03 0,02561908 ! cell maturation GO:0048469 32 32 2,000 3,732E-03 0,02795692 ! morphogenesis of a branching structure GO:0001763 32 32 2,000 3,732E-03 0,02784374 ! regulation of lymphocyte differentiation GO:0045619 32 32 2,000 3,732E-03 0,02773146 ! kidney development GO:0001822 32 32 2,000 3,732E-03 0,02762009 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 4,116E-03 0,03034066 ! regulation of cell killing GO:0031341 10 10 1,000 4,116E-03 0,03021978 ! positive regulation of anti-apoptosis GO:0045768 10 10 1,000 4,116E-03 0,03009986 GO:0045767|regulation of anti-apoptosis, ! hormone secretion GO:0046879 10 10 1,000 4,116E-03 0,02998088 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 4,116E-03 0,02986285 ! exocrine system development GO:0035272 10 10 1,000 4,116E-03 0,02974574 ! neuromuscular junction development GO:0007528 10 10 1,000 4,116E-03 0,02962955 ! embryo implantation GO:0007566 11 10 1,000 4,116E-03 0,02951426 ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 1,000 4,116E-03 0,02939986 ! histone deacetylation GO:0016575 10 10 1,000 4,116E-03 0,02928635 ! gland morphogenesis GO:0022612 10 10 1,000 4,116E-03 0,02917371 ! regulation of erythrocyte differentiation GO:0045646 10 10 1,000 4,116E-03 0,02906193 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 4,116E-03 0,02895101 ! gut development GO:0048565 10 10 1,000 4,116E-03 0,02884093 ! embryonic organ morphogenesis GO:0048562 10 10 1,000 4,116E-03 0,02873168 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 4,116E-03 0,02862326 ! striated muscle tissue development GO:0014706 69 67 3,000 4,192E-03 0,02904183 ! response to radiation GO:0009314 70 68 3,000 4,421E-03 0,03051554 ! regulation of bone remodeling GO:0046850 34 34 2,000 4,439E-03 0,03052733 ! viral reproduction GO:0016032 34 34 2,000 4,439E-03 0,03041385 ! regulation of translation GO:0006417 69 69 3,000 4,658E-03 0,03179822 ! regionalization GO:0003002 70 69 3,000 4,658E-03 0,03168088 ! regulation of tissue remodeling GO:0034103 35 35 2,000 4,821E-03 0,03266775 ! regulation of immune effector process GO:0002697 35 35 2,000 4,821E-03 0,03254809 ! muscle tissue development GO:0060537 72 70 3,000 4,904E-03 0,03298902 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 1,000 4,998E-03 0,03349739 ! protein amino acid acetylation GO:0006473 11 11 1,000 4,998E-03 0,03337602 ! T cell proliferation GO:0042098 11 11 1,000 4,998E-03 0,03325553 ! spinal cord development GO:0021510 11 11 1,000 4,998E-03 0,0331359 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 4,998E-03 0,03301714 ! G1/S transition checkpoint GO:0031575 12 11 1,000 4,998E-03 0,03289922 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 1,000 4,998E-03 0,03278214 ! negative regulation of angiogenesis GO:0016525 11 11 1,000 4,998E-03 0,03266589 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 4,998E-03 0,03255046 GO:0006109|regulation of carbohydrate metabolic process, ! muscle maintenance GO:0046716 12 11 1,000 4,998E-03 0,03243585 ! hindbrain development GO:0030902 11 11 1,000 4,998E-03 0,03232204 ! proximal/distal pattern formation GO:0009954 11 11 1,000 4,998E-03 0,03220903 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 4,998E-03 0,0320968 ! calcium ion homeostasis GO:0055074 71 71 3,000 5,159E-03 0,03301499 GO:0006874|cellular calcium ion homeostasis, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 2,000 5,223E-03 0,03330631 ! regulation of cytokine production GO:0001817 72 72 3,000 5,423E-03 0,03446118 ! regulation of transcription factor activity GO:0051090 38 37 2,000 5,644E-03 0,03574399 GO:0090046|regulation of transcription regulator activity, ! adaptive immune response GO:0002250 37 37 2,000 5,644E-03 0,03562158 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 5,96E-03 0,03748761 ! positive regulation of angiogenesis GO:0045766 12 12 1,000 5,96E-03 0,0373601 ! initiation of viral infection GO:0019059 12 12 1,000 5,96E-03 0,03723345 ! positive regulation of innate immune response GO:0045089 12 12 1,000 5,96E-03 0,03710766 ! acute-phase response GO:0006953 12 12 1,000 5,96E-03 0,03698272 ! regulation of alpha-beta T cell activation GO:0046634 12 12 1,000 5,96E-03 0,03685862 ! regulation of interleukin-6 production GO:0032675 12 12 1,000 5,96E-03 0,03673535 ! somitogenesis GO:0001756 13 12 1,000 5,96E-03 0,0366129 ! G1 phase GO:0051318 13 12 1,000 5,96E-03 0,03649126 ! hormone transport GO:0009914 12 12 1,000 5,96E-03 0,03637043 ! neurotransmitter secretion GO:0007269 14 12 1,000 5,96E-03 0,03625039 ! positive regulation of secretion GO:0051047 39 38 2,000 6,085E-03 0,03688825 ! RNA elongation GO:0006354 38 38 2,000 6,085E-03 0,03676731 ! steroid hormone receptor signaling pathway GO:0030518 38 38 2,000 6,085E-03 0,03664715 ! regulation of homeostatic process GO:0032844 38 38 2,000 6,085E-03 0,03652778 ! positive regulation of protein modification process GO:0031401 39 39 2,000 6,546E-03 0,03916737 ! nucleotide-excision repair GO:0006289 40 39 2,000 6,546E-03 0,03904061 ! developmental maturation GO:0021700 39 39 2,000 6,546E-03 0,03891467 ! cellular metal ion homeostasis GO:0006875 77 77 3,000 6,875E-03 0,04074206 ! positive regulation of DNA replication GO:0045740 14 13 1,000 6,999E-03 0,04134127 ! negative regulation of hormone secretion GO:0046888 13 13 1,000 6,999E-03 0,04120919 ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 1,000 6,999E-03 0,04107795 ! vasculogenesis GO:0001570 13 13 1,000 6,999E-03 0,04094755 ! regulation of innate immune response GO:0045088 13 13 1,000 6,999E-03 0,04081797 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 6,999E-03 0,0406892 ! response to corticosteroid stimulus GO:0031960 13 13 1,000 6,999E-03 0,04056125 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 1,000 6,999E-03 0,0404341 ! actin filament bundle formation GO:0051017 13 13 1,000 6,999E-03 0,04030774 ! ureteric bud development GO:0001657 13 13 1,000 6,999E-03 0,04018217 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 6,999E-03 0,04005738 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 6,999E-03 0,03993337 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 1,000 6,999E-03 0,03981012 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 1,000 6,999E-03 0,03968762 ! neural crest cell migration GO:0001755 14 13 1,000 6,999E-03 0,03956588 ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 1,000 6,999E-03 0,03944488 ! negative regulation of intracellular transport GO:0032387 13 13 1,000 6,999E-03 0,03932463 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 6,999E-03 0,0392051 ! response to cytokine stimulus GO:0034097 13 13 1,000 6,999E-03 0,03908629 ! camera-type eye morphogenesis GO:0048593 13 13 1,000 6,999E-03 0,03896821 ! tissue homeostasis GO:0001894 13 13 1,000 6,999E-03 0,03885084 GO:0048871|multicellular organismal homeostasis, ! DNA catabolic process GO:0006308 41 40 2,000 7,027E-03 0,03889033 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 2,000 7,027E-03 0,03877389 ! myeloid cell differentiation GO:0030099 42 40 2,000 7,027E-03 0,03865815 ! regulation of protein modification process GO:0031399 79 78 3,000 7,194E-03 0,03945777 ! metal ion homeostasis GO:0055065 78 78 3,000 7,194E-03 0,03934069 ! cell cycle checkpoint GO:0000075 42 41 2,000 7,529E-03 0,04105095 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 2,000 7,529E-03 0,04092986 ! leukocyte mediated immunity GO:0002443 41 41 2,000 7,529E-03 0,04080947 ! cytosolic calcium ion homeostasis GO:0051480 42 42 2,000 8,051E-03 0,04351362 ! neuron fate commitment GO:0048663 14 14 1,000 8,113E-03 0,04372135 ! cellular iron ion homeostasis GO:0006879 14 14 1,000 8,113E-03 0,04359388 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 1,000 8,113E-03 0,04346716 ! protein amino acid acylation GO:0043543 14 14 1,000 8,113E-03 0,04334116 ! protein amino acid deacetylation GO:0006476 14 14 1,000 8,113E-03 0,0432159 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 1,000 8,113E-03 0,04309136 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 1,000 8,113E-03 0,04296753 ! positive regulation of inflammatory response GO:0050729 14 14 1,000 8,113E-03 0,04284442 ! positive regulation of osteoblast differentiation GO:0045669 14 14 1,000 8,113E-03 0,042722 ! response to molecule of bacterial origin GO:0002237 14 14 1,000 8,113E-03 0,04260029 ! reproductive structure development GO:0048608 43 43 2,000 8,594E-03 0,04499887 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 2,000 8,594E-03 0,0448714 ! humoral immune response GO:0006959 44 44 2,000 9,159E-03 0,04768341 ! striated muscle cell differentiation GO:0051146 16 15 1,000 9,302E-03 0,04829205 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 1,000 9,302E-03 0,0481564 ! leukocyte homeostasis GO:0001776 15 15 1,000 9,302E-03 0,04802151 ! regulation of cytokine secretion GO:0050707 15 15 1,000 9,302E-03 0,04788737 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 9,302E-03 0,04775398 ! positive regulation of fibroblast proliferation GO:0048146 15 15 1,000 9,302E-03 0,04762133 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 9,302E-03 0,04748941 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 9,302E-03 0,04735823 ! response to ionizing radiation GO:0010212 16 15 1,000 9,302E-03 0,04722776 ! regulation of production of molecular mediator of immune response GO:0002700 15 15 1,000 9,302E-03 0,04709802 ! glutathione metabolic process GO:0006749 16 15 1,000 9,302E-03 0,04696898 ! positive regulation of B cell activation GO:0050871 15 15 1,000 9,302E-03 0,04684065 ! negative regulation of cell activation GO:0050866 15 15 1,000 9,302E-03 0,04671302 ! positive regulation of immune effector process GO:0002699 15 15 1,000 9,302E-03 0,04658608 ! positive regulation of cell differentiation GO:0045597 87 85 3,000 9,699E-03 0,04844363 ! positive regulation of response to stimulus GO:0048584 86 85 3,000 9,699E-03 0,0483127 ! regulation of DNA binding GO:0051101 47 45 2,000 9,745E-03 0,04840816 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 2,000 0,01035182 0,05128601 ! tube morphogenesis GO:0035239 47 46 2,000 0,01035182 0,05114851 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 2,000 0,01035182 0,05101175 ! circadian rhythm GO:0007623 16 16 1,000 0,01056353 0,05191622 ! positive regulation of mitosis GO:0045840 16 16 1,000 0,01056353 0,05177815 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 0,01056353 0,0516408 ! segmentation GO:0035282 17 16 1,000 0,01056353 0,05150419 ! iron ion homeostasis GO:0055072 16 16 1,000 0,01056353 0,05136829 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 1,000 0,01056353 0,05123311 ! lymphocyte proliferation GO:0046651 16 16 1,000 0,01056353 0,05109864 ! cell fate specification GO:0001708 16 16 1,000 0,01056353 0,05096488 ! positive regulation of MAPKKK cascade GO:0043410 17 16 1,000 0,01056353 0,05083181 ! serine family amino acid metabolic process GO:0009069 16 16 1,000 0,01056353 0,05069944 ! male gamete generation GO:0048232 90 88 3,000 0,01092711 0,05230821 GO:0007283|spermatogenesis, ! regulation of catabolic process GO:0009894 48 47 2,000 0,01098052 0,05242772 ! protein localization in nucleus GO:0034504 48 48 2,000 0,01163092 0,05538963 ! brain development GO:0007420 91 90 3,000 0,01179913 0,05604587 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 0,01189617 0,05636154 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 1,000 0,01189617 0,05621702 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 0,01189617 0,05607324 ! myelination GO:0042552 17 17 1,000 0,01189617 0,0559302 ! leukocyte adhesion GO:0007159 17 17 1,000 0,01189617 0,05578788 ! glucose transport GO:0015758 17 17 1,000 0,01189617 0,05564629 ! neural crest cell development GO:0014032 19 17 1,000 0,01189617 0,05550541 GO:0014033|neural crest cell differentiation, ! cell recognition GO:0008037 18 17 1,000 0,01189617 0,05536525 ! regulation of osteoblast differentiation GO:0045667 17 17 1,000 0,01189617 0,05522579 ! negative regulation of cell cycle GO:0045786 92 91 3,000 0,01225147 0,05673231 ! skeletal muscle tissue development GO:0007519 50 49 2,000 0,01230314 0,0568288 GO:0060538|skeletal muscle organ development, ! response to bacterium GO:0009617 50 49 2,000 0,01230314 0,05668673 ! positive regulation of immune system process GO:0002684 92 92 3,000 0,01271482 0,05843744 ! regulation of defense response GO:0031347 50 50 2,000 0,0129973 0,05958713 ! negative regulation of transport GO:0051051 51 50 2,000 0,0129973 0,05943927 ! transcription initiation GO:0006352 50 50 2,000 0,0129973 0,05929214 ! anatomical structure homeostasis GO:0060249 51 50 2,000 0,0129973 0,05914574 ! tissue morphogenesis GO:0048729 94 93 3,000 0,01318927 0,0598715 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 0,01329848 0,06021892 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 1,000 0,01329848 0,06007132 ! mononuclear cell proliferation GO:0032943 18 18 1,000 0,01329848 0,05992445 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 1,000 0,01329848 0,05977829 ! hexose transport GO:0008645 18 18 1,000 0,01329848 0,05963285 GO:0015749|monosaccharide transport, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 0,01329848 0,05948811 ! telencephalon development GO:0021537 19 18 1,000 0,01329848 0,05934407 ! ensheathment of neurons GO:0007272 18 18 1,000 0,01329848 0,05920072 GO:0008366|axon ensheathment, ! pattern specification process GO:0007389 96 94 3,000 0,01367492 0,06072981 ! regulation of cell growth GO:0001558 97 96 3,000 0,01468013 0,06503721 ! DNA damage checkpoint GO:0000077 19 19 1,000 0,014769 0,06527403 ! glial cell differentiation GO:0010001 19 19 1,000 0,014769 0,06511787 ! positive regulation of T cell proliferation GO:0042102 19 19 1,000 0,014769 0,06496246 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 0,014769 0,06480778 ! metanephros development GO:0001656 19 19 1,000 0,014769 0,06465385 ! cellular response to oxidative stress GO:0034599 19 19 1,000 0,014769 0,06450064 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 1,000 0,014769 0,06434815 ! positive regulation of T cell differentiation GO:0045582 19 19 1,000 0,014769 0,06419639 ! peripheral nervous system development GO:0007422 19 19 1,000 0,014769 0,06404534 ! eye morphogenesis GO:0048592 19 19 1,000 0,014769 0,063895 ! regulation of cell shape GO:0008360 21 19 1,000 0,014769 0,06374536 ! placenta development GO:0001890 19 19 1,000 0,014769 0,06359642 ! response to heat GO:0009408 19 19 1,000 0,014769 0,06344818 ! regulation of T cell activation GO:0050863 53 53 2,000 0,0152124 0,06520106 ! blood circulation GO:0008015 99 98 3,000 0,01573113 0,0672679 GO:0003013|circulatory system process, ! response to virus GO:0009615 54 54 2,000 0,01599526 0,06823905 ! negative regulation of multicellular organismal process GO:0051241 55 54 2,000 0,01599526 0,06808145 ! anti-apoptosis GO:0006916 100 99 3,000 0,01627399 0,06910822 ! ectoderm development GO:0007398 99 99 3,000 0,01627399 0,06894935 ! neural tube development GO:0021915 21 20 1,000 0,01630629 0,06892772 ! nucleus organization GO:0006997 20 20 1,000 0,01630629 0,06876999 ! protein targeting to membrane GO:0006612 22 20 1,000 0,01630629 0,06861298 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 0,01630629 0,06845668 ! lipid oxidation GO:0034440 20 20 1,000 0,01630629 0,0683011 GO:0019395|fatty acid oxidation, ! regulation of B cell activation GO:0050864 20 20 1,000 0,01630629 0,06814622 ! muscle organ development GO:0007517 102 100 3,000 0,01682854 0,07016968 ! response to other organism GO:0051707 101 100 3,000 0,01682854 0,07001128 ! reproductive developmental process GO:0003006 56 56 2,000 0,01762815 0,07317271 ! DNA integrity checkpoint GO:0031570 21 21 1,000 0,01790891 0,07417106 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 0,01790891 0,07400476 ! regulation of leukocyte mediated immunity GO:0002703 21 21 1,000 0,01790891 0,0738392 ! regulation of action potential in neuron GO:0019228 21 21 1,000 0,01790891 0,07367438 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 1,000 0,01790891 0,0735103 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 0,01790891 0,07334694 ! negative regulation of protein transport GO:0051224 21 21 1,000 0,01790891 0,07318431 ! regulation of binding GO:0051098 60 57 2,000 0,01847829 0,07534399 ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 0,01957548 0,07964151 ! odontogenesis GO:0042476 22 22 1,000 0,01957548 0,07946608 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 1,000 0,01957548 0,07929143 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! maintenance of protein location in cell GO:0032507 23 22 1,000 0,01957548 0,07911755 ! respiratory gaseous exchange GO:0007585 22 22 1,000 0,01957548 0,07894442 ! regulation of adaptive immune response GO:0002819 22 22 1,000 0,01957548 0,07877206 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 1,000 0,01957548 0,07860044 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 1,000 0,01957548 0,07842957 ! fatty acid catabolic process GO:0009062 23 22 1,000 0,01957548 0,07825944 ! protein localization in organelle GO:0033365 59 59 2,000 0,02024616 0,08076552 ! immune effector process GO:0002252 59 59 2,000 0,02024616 0,08059108 ! protein polymerization GO:0051258 65 60 2,000 0,02116395 0,08406285 ! epithelial cell differentiation GO:0030855 23 23 1,000 0,0213046 0,08443952 ! regulation of hormone secretion GO:0046883 23 23 1,000 0,0213046 0,08425831 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 0,0213046 0,08407789 ! calcium-mediated signaling GO:0019722 23 23 1,000 0,0213046 0,08389824 ! regulation of lymphocyte activation GO:0051249 62 62 2,000 0,02306734 0,0906463 ! regulation of action potential GO:0001508 24 24 1,000 0,02309492 0,09056156 ! gliogenesis GO:0042063 24 24 1,000 0,02309492 0,09036928 ! cellular amino acid biosynthetic process GO:0008652 24 24 1,000 0,02309492 0,09017782 ! maintenance of protein location GO:0045185 25 24 1,000 0,02309492 0,08998717 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 0,02309492 0,08979733 ! glucan metabolic process GO:0044042 25 24 1,000 0,02309492 0,08960828 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of secretion GO:0051046 65 63 2,000 0,02405296 0,09312942 ! negative regulation of secretion GO:0051048 26 25 1,000 0,02494509 0,09638114 ! heart morphogenesis GO:0003007 25 25 1,000 0,02494509 0,09617951 ! negative regulation of immune system process GO:0002683 25 25 1,000 0,02494509 0,09597872 ! regulation of response to external stimulus GO:0032101 65 64 2,000 0,02506118 0,09622451 ! regulation of hormone levels GO:0010817 66 65 2,000 0,02609201 0,09997416 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 1,000 0,0268538 0,10267958 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 0,0268538 0,10246699 ! cellular defense response GO:0006968 26 26 1,000 0,0268538 0,10225529 ! response to insulin stimulus GO:0032868 28 26 1,000 0,0268538 0,10204445 ! maintenance of location in cell GO:0051651 27 26 1,000 0,0268538 0,10183448 ! synapse organization GO:0050808 26 26 1,000 0,0268538 0,10162538 ! Ras protein signal transduction GO:0007265 69 67 2,000 0,02822137 0,10658194 ! regulation of neurotransmitter levels GO:0001505 31 27 1,000 0,02881975 0,10861921 ! energy reserve metabolic process GO:0006112 28 27 1,000 0,02881975 0,10839754 ! learning or memory GO:0007611 28 27 1,000 0,02881975 0,10817677 ! peptide metabolic process GO:0006518 29 27 1,000 0,02881975 0,1079569 ! mesenchymal cell development GO:0014031 29 27 1,000 0,02881975 0,10773792 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! defense response to bacterium GO:0042742 27 27 1,000 0,02881975 0,10751982 ! cell growth GO:0016049 27 27 1,000 0,02881975 0,10730261 ! regulation of leukocyte activation GO:0002694 69 69 2,000 0,03044083 0,11310977 ! regulation of mitotic cell cycle GO:0007346 72 69 2,000 0,03044083 0,11288219 ! carbohydrate transport GO:0008643 28 28 1,000 0,03084164 0,11413884 ! developmental growth GO:0048589 28 28 1,000 0,03084164 0,11391011 ! cartilage development GO:0051216 29 28 1,000 0,03084164 0,11368229 ! growth GO:0040007 70 70 2,000 0,03158425 0,11618716 ! negative regulation of signal transduction GO:0009968 71 71 2,000 0,03275006 0,12023577 ! regulation of cell activation GO:0050865 71 71 2,000 0,03275006 0,11999674 ! DNA-dependent DNA replication GO:0006261 29 29 1,000 0,03291822 0,12037359 ! response to UV GO:0009411 29 29 1,000 0,03291822 0,12013522 ! secretion by cell GO:0032940 75 72 2,000 0,03393821 0,12361289 ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,03504825 0,1274042 GO:0010863|positive regulation of phospholipase C activity, ! response to temperature stimulus GO:0009266 30 30 1,000 0,03504825 0,1271534 ! regulation of ossification GO:0030278 30 30 1,000 0,03504825 0,12690359 ! vascular process in circulatory system GO:0003018 31 30 1,000 0,03504825 0,12665476 ! regulation of inflammatory response GO:0050727 30 30 1,000 0,03504825 0,1264069 ! regulation of translational initiation GO:0006446 31 31 1,000 0,0372305 0,13401525 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,0372305 0,13375401 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,0372305 0,13349379 ! regulation of DNA replication GO:0006275 32 31 1,000 0,0372305 0,13323458 ! camera-type eye development GO:0043010 31 31 1,000 0,0372305 0,13297637 ! negative regulation of cell communication GO:0010648 76 76 2,000 0,03891292 0,13871667 ! positive regulation of multicellular organismal process GO:0051240 76 76 2,000 0,03891292 0,13844888 ! muscle fiber development GO:0048747 32 32 1,000 0,03946376 0,14013815 ! lipid modification GO:0030258 32 32 1,000 0,03946376 0,13986866 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,03946376 0,13960019 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,03946376 0,13933276 ! maintenance of location GO:0051235 33 32 1,000 0,03946376 0,13906635 ! cell morphogenesis involved in differentiation GO:0000904 82 77 2,000 0,04021176 0,1414318 ! microtubule-based movement GO:0007018 82 78 2,000 0,04153248 0,14579879 ! positive regulation of protein kinase cascade GO:0010740 79 78 2,000 0,04153248 0,1455216 ! regulation of immune response GO:0050776 78 78 2,000 0,04153248 0,14524547 ! response to metal ion GO:0010038 34 34 1,000 0,04407857 0,15385757 ! muscle cell differentiation GO:0042692 35 34 1,000 0,04407857 0,15356673 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 0,04407857 0,15327698 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,04407857 0,15298832 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 0,04407857 0,15270075 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 0,04407857 0,15241426 ! detection of stimulus GO:0051606 36 34 1,000 0,04407857 0,15212884 ! neuron projection development GO:0031175 85 80 2,000 0,04423925 0,152398 ! acute inflammatory response GO:0002526 35 35 1,000 0,0464578 0,15974201 ! regulation of cytokine biosynthetic process GO:0042035 35 35 1,000 0,0464578 0,15944454 ! mesoderm development GO:0007498 35 35 1,000 0,0464578 0,15914817 ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,0464578 0,15885291 ! response to steroid hormone stimulus GO:0048545 35 35 1,000 0,0464578 0,15855874 ! rRNA transcription GO:0009303 5 5 0,000 0,04846515 0,165104 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,04846515 0,16479938 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,04846515 0,16449588 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! reproductive cellular process GO:0048610 5 5 0,000 0,04846515 0,1641935 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,04846515 0,16389222 ! metencephalon development GO:0022037 5 5 0,000 0,04846515 0,16359206 ! water transport GO:0006833 5 5 0,000 0,04846515 0,16329298 GO:0042044|fluid transport, ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,04846515 0,162995 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,04846515 0,16269811 ! glycerol metabolic process GO:0006071 5 5 0,000 0,04846515 0,1624023 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,04846515 0,16210755 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,04846515 0,16181388 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,04846515 0,16152127 ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,04846515 0,16122972 ! filopodium assembly GO:0046847 7 5 0,000 0,04846515 0,16093921 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,04846515 0,16064975 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,04846515 0,16036133 ! GTP metabolic process GO:0046039 5 5 0,000 0,04846515 0,16007395 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,04846515 0,15978759 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,04846515 0,15950225 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,04846515 0,15921794 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,04846515 0,15893463 ! social behavior GO:0035176 5 5 0,000 0,04846515 0,15865233 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,04846515 0,15837103 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,04846515 0,15809073 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,04846515 0,15781142 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,04846515 0,15753309 ! response to lipid GO:0033993 5 5 0,000 0,04846515 0,15725574 ! hippocampus development GO:0021766 6 5 0,000 0,04846515 0,15697937 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,04846515 0,15670397 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,04846515 0,15642953 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,04846515 0,15615605 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,04846515 0,15588353 ! mechanosensory behavior GO:0007638 5 5 0,000 0,04846515 0,15561196 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,04846515 0,15534133 ! response to interferon-gamma GO:0034341 5 5 0,000 0,04846515 0,15507164 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,04846515 0,15480288 ! pH reduction GO:0045851 5 5 0,000 0,04846515 0,15453506 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,04846515 0,15426816 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,04846515 0,15400218 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,04846515 0,15373711 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,04846515 0,15347296 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,04846515 0,15320971 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,04846515 0,15294737 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,04846515 0,15268592 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,04846515 0,15242536 ! adrenal gland development GO:0030325 5 5 0,000 0,04846515 0,15216569 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,04846515 0,15190691 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! ovulation GO:0030728 5 5 0,000 0,04846515 0,151649 ! astrocyte differentiation GO:0048708 5 5 0,000 0,04846515 0,15139197 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,04846515 0,15113581 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,04846515 0,15088051 ! tyrosine metabolic process GO:0006570 5 5 0,000 0,04846515 0,15062607 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,04846515 0,1503725 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,04846515 0,15011977 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,04846515 0,14986789 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,04846515 0,14961685 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,04846515 0,14936666 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,04846515 0,1491173 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,04846515 0,14886877 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,04846515 0,14862107 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,04846515 0,14837419 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,04846515 0,14812813 ! response to ATP GO:0033198 5 5 0,000 0,04846515 0,14788288 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,04846515 0,14763845 ! regulation of appetite GO:0032098 5 5 0,000 0,04846515 0,14739482 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,04846515 0,147152 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,04846515 0,14690997 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,04846515 0,14666874 ! receptor clustering GO:0043113 5 5 0,000 0,04846515 0,1464283 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,04846515 0,14618865 ! fear response GO:0042596 5 5 0,000 0,04846515 0,14594978 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,04846515 0,14571168 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,04846515 0,14547437 ! retinol metabolic process GO:0042572 5 5 0,000 0,04846515 0,14523783 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,04846515 0,14500205 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,04846515 0,14476704 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,04846515 0,14453279 ! parturition GO:0007567 5 5 0,000 0,04846515 0,14429929 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,04846515 0,14406655 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,04846515 0,14383456 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,04846515 0,14360332 ! protein heterooligomerization GO:0051291 5 5 0,000 0,04846515 0,14337281 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,04846515 0,14314305 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,04846515 0,14291402 ! response to UV-B GO:0010224 5 5 0,000 0,04846515 0,14268572 ! oligodendrocyte development GO:0014003 5 5 0,000 0,04846515 0,14245815 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,04846515 0,14223131 ! interaction with symbiont GO:0051702 5 5 0,000 0,04846515 0,14200519 ! cellular extravasation GO:0045123 5 5 0,000 0,04846515 0,14177978 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,04846515 0,14155509 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,04846515 0,14133111 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,04846515 0,14110784 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,04846515 0,14088527 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,04846515 0,14066341 ! response to amine stimulus GO:0014075 5 5 0,000 0,04846515 0,14044224 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,04846515 0,14022176 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,04846515 0,14000198 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,04846515 0,13978288 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,04846515 0,13956447 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,04846515 0,13934674 ! neuron recognition GO:0008038 5 5 0,000 0,04846515 0,13912969 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,04846515 0,13891332 ! decidualization GO:0046697 5 5 0,000 0,04846515 0,13869761 ! hair follicle maturation GO:0048820 5 5 0,000 0,04846515 0,13848258 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,04846515 0,13826821 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,04846515 0,1380545 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,04846515 0,13784145 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,04846515 0,13762906 ! postreplication repair GO:0006301 5 5 0,000 0,04846515 0,13741733 ! cellular pigmentation GO:0033059 5 5 0,000 0,04846515 0,13720624 ! histone methylation GO:0016571 5 5 0,000 0,04846515 0,1369958 ! DNA methylation GO:0006306 5 5 0,000 0,04846515 0,13678601 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,04846515 0,13657685 ! T cell lineage commitment GO:0002360 5 5 0,000 0,04846515 0,13636834 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,04846515 0,13616046 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,04846515 0,13595322 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,04846515 0,1357466 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,04846515 0,13554061 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,04846515 0,13533525 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,04846515 0,1351305 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,04846515 0,13492638 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,04846515 0,13472287 ! sterol catabolic process GO:0016127 5 5 0,000 0,04846515 0,13451997 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,04846515 0,13431769 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,04846515 0,13411601 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,04846515 0,13391494 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,04846515 0,13371446 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,04846515 0,13351459 ! zymogen activation GO:0031638 5 5 0,000 0,04846515 0,13331532 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,04846515 0,13311664 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,04846515 0,13291855 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,04846515 0,13272104 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,04846515 0,13252413 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,04846515 0,1323278 ! nucleosome positioning GO:0016584 5 5 0,000 0,04846515 0,13213204 ! regulation of isotype switching GO:0045191 5 5 0,000 0,04846515 0,13193687 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,04846515 0,13174227 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,04846515 0,13154825 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,04846515 0,1313548 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,04846515 0,13116191 ! NADPH regeneration GO:0006740 5 5 0,000 0,04846515 0,13096959 GO:0006098|pentose-phosphate shunt, ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,04846515 0,13077784 ! musculoskeletal movement GO:0050881 5 5 0,000 0,04846515 0,13058664 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,04846515 0,130396 ! sarcomere organization GO:0045214 5 5 0,000 0,04846515 0,13020592 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,04846515 0,13001639 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,04846515 0,12982742 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,04846515 0,12963899 GO:0046325|negative regulation of glucose import, ! oocyte differentiation GO:0009994 5 5 0,000 0,04846515 0,1294511 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,04846515 0,12926377 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,04846515 0,12907697 ! spleen development GO:0048536 5 5 0,000 0,04846515 0,12889071 ! male genitalia development GO:0030539 5 5 0,000 0,04846515 0,12870499 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,04846515 0,1285198 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,04846515 0,12833515 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,04846515 0,12815102 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,04846515 0,12796742 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,04846515 0,12778435 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,04846515 0,1276018 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,04846515 0,12741978 ! ATP catabolic process GO:0006200 5 5 0,000 0,04846515 0,12723827 ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,04846515 0,12705727 ! blastocyst formation GO:0001825 5 5 0,000 0,04846515 0,12687679 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,04846515 0,12669683 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,04846515 0,12651737 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,04846515 0,12633842 ! activation of innate immune response GO:0002218 5 5 0,000 0,04846515 0,12615998 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,04846515 0,12598203 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,04846515 0,12580459 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,04846515 0,12562765 ! muscle adaptation GO:0043500 5 5 0,000 0,04846515 0,12545121 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,04846515 0,12527526 ! embryonic heart tube development GO:0035050 5 5 0,000 0,04846515 0,12509981 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,04846515 0,12492484 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,04846515 0,12475037 ! defense response to fungus GO:0050832 5 5 0,000 0,04846515 0,12457638 ! lysogeny GO:0030069 5 5 0,000 0,04846515 0,12440287 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,04846515 0,12422985 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,04846515 0,12405731 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,04846515 0,12388525 ! response to nicotine GO:0035094 5 5 0,000 0,04846515 0,12371366 ! establishment of cell polarity GO:0030010 5 5 0,000 0,04846515 0,12354255 ! mitochondrion localization GO:0051646 5 5 0,000 0,04846515 0,12337191 ! nucleus localization GO:0051647 5 5 0,000 0,04846515 0,12320174 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,04846515 0,12303204 ! response to inorganic substance GO:0010035 36 36 1,000 0,04888339 0,12392308 ! regulation of mitosis GO:0007088 37 36 1,000 0,04888339 0,12375286 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 1,000 0,04888339 0,1235831 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 1,000 0,04888339 0,12341381 ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,04888339 0,12324498 ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 0,04888339 0,12307661 ! regulation of lipase activity GO:0060191 36 36 1,000 0,04888339 0,12290871 ! coagulation GO:0050817 39 36 1,000 0,04888339 0,12274126 GO:0007596|blood coagulation, ! meiosis GO:0007126 37 37 1,000 0,05135422 0,12876984 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 0,05135422 0,12859488 ! lymphocyte mediated immunity GO:0002449 37 37 1,000 0,05135422 0,12842039 ! eye development GO:0001654 37 37 1,000 0,05135422 0,12824638 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,05135422 0,12807284 ! neurotransmitter transport GO:0006836 40 38 1,000 0,0538692 0,13416342 ! exocytosis GO:0006887 40 38 1,000 0,0538692 0,13398236 ! negative regulation of kinase activity GO:0033673 38 38 1,000 0,0538692 0,13380179 ! cell-matrix adhesion GO:0007160 39 38 1,000 0,0538692 0,13362171 ! meiotic cell cycle GO:0051321 38 38 1,000 0,0538692 0,13344211 ! axon guidance GO:0007411 39 38 1,000 0,0538692 0,13326299 ! hemostasis GO:0007599 42 39 1,000 0,05642723 0,139404 ! activation of MAPK activity GO:0000187 39 39 1,000 0,05642723 0,13921738 ! response to unfolded protein GO:0006986 39 39 1,000 0,05642723 0,13903126 ! regulation of MAPKKK cascade GO:0043408 41 39 1,000 0,05642723 0,13884564 ! positive regulation of T cell activation GO:0050870 39 39 1,000 0,05642723 0,13866051 ! limb development GO:0060173 39 39 1,000 0,05642723 0,13847588 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! axon extension GO:0048675 7 6 0,000 0,05787669 0,14184407 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,05787669 0,1416557 ! tRNA modification GO:0006400 6 6 0,000 0,05787669 0,14146782 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,05787669 0,14128045 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,05787669 0,14109357 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,05787669 0,14090719 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,05787669 0,14072129 ! virus-host interaction GO:0019048 6 6 0,000 0,05787669 0,14053589 ! regulation of S phase GO:0033261 6 6 0,000 0,05787669 0,14035097 ! myotube differentiation GO:0014902 6 6 0,000 0,05787669 0,14016654 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,05787669 0,1399826 ! bone remodeling GO:0046849 6 6 0,000 0,05787669 0,13979913 ! N-glycan processing GO:0006491 6 6 0,000 0,05787669 0,13961615 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,05787669 0,13943365 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,05787669 0,13925162 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,05787669 0,13907006 ! RNA methylation GO:0001510 6 6 0,000 0,05787669 0,13888898 ! cartilage condensation GO:0001502 7 6 0,000 0,05787669 0,13870837 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,05787669 0,13852823 ! succinate metabolic process GO:0006105 7 6 0,000 0,05787669 0,13834856 ! artery development GO:0060840 6 6 0,000 0,05787669 0,13816935 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,05787669 0,13799061 ! bile acid metabolic process GO:0008206 6 6 0,000 0,05787669 0,13781232 ! androgen metabolic process GO:0008209 6 6 0,000 0,05787669 0,1376345 ! estrogen metabolic process GO:0008210 6 6 0,000 0,05787669 0,13745714 ! limbic system development GO:0021761 7 6 0,000 0,05787669 0,13728023 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,05787669 0,13710378 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,05787669 0,13692778 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,05787669 0,13675223 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,05787669 0,13657713 ! pathogenesis GO:0009405 6 6 0,000 0,05787669 0,13640248 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,05787669 0,13622828 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,05787669 0,13605451 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,05787669 0,1358812 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,05787669 0,13570832 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,05787669 0,13553588 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,05787669 0,13536388 ! arginine metabolic process GO:0006525 6 6 0,000 0,05787669 0,13519232 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,05787669 0,13502119 ! glutamate catabolic process GO:0006538 7 6 0,000 0,05787669 0,13485049 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,05787669 0,13468023 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,05787669 0,13451039 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,05787669 0,13434098 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,05787669 0,134172 ! V(D)J recombination GO:0033151 6 6 0,000 0,05787669 0,13400344 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,05787669 0,13383531 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,05787669 0,13366759 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,05787669 0,1335003 ! regulation of heart rate GO:0002027 6 6 0,000 0,05787669 0,13333342 ! lipid digestion GO:0044241 6 6 0,000 0,05787669 0,13316697 ! asymmetric protein localization GO:0008105 6 6 0,000 0,05787669 0,13300092 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,05787669 0,13283529 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,05787669 0,13267007 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,05787669 0,13250527 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,05787669 0,13234087 ! ruffle organization GO:0031529 6 6 0,000 0,05787669 0,13217688 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,05787669 0,13201329 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,05787669 0,13185011 ! neutral amino acid transport GO:0015804 6 6 0,000 0,05787669 0,13168733 ! L-amino acid transport GO:0015807 6 6 0,000 0,05787669 0,13152496 ! bone mineralization GO:0030282 6 6 0,000 0,05787669 0,13136298 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,05787669 0,1312014 ! negative regulation of ossification GO:0030279 6 6 0,000 0,05787669 0,13104022 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,05787669 0,13087943 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,05787669 0,13071904 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,05787669 0,13055904 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,05787669 0,13039944 ! regulation of organ growth GO:0046620 6 6 0,000 0,05787669 0,13024022 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,05787669 0,13008139 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,05787669 0,12992295 ! response to dsRNA GO:0043331 6 6 0,000 0,05787669 0,12976489 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,05787669 0,12960722 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,05787669 0,12944993 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,05787669 0,12929302 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,05787669 0,12913649 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,05787669 0,12898034 ! multicellular organismal aging GO:0010259 6 6 0,000 0,05787669 0,12882456 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,05787669 0,12866917 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,05787669 0,12851414 ! renal water homeostasis GO:0003091 6 6 0,000 0,05787669 0,12835949 ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,05787669 0,12820522 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,05787669 0,12805131 ! ribosome assembly GO:0042255 6 6 0,000 0,05787669 0,12789777 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,05787669 0,1277446 ! diencephalon development GO:0021536 6 6 0,000 0,05787669 0,12759179 ! fucose catabolic process GO:0019317 6 6 0,000 0,05787669 0,12743935 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,05787669 0,12728728 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,05787669 0,12713557 ! regulation of lipid transport GO:0032368 6 6 0,000 0,05787669 0,12698421 ! regulation of cell division GO:0051302 6 6 0,000 0,05787669 0,12683322 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,05787669 0,12668259 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,05787669 0,12653231 ! neuroblast proliferation GO:0007405 6 6 0,000 0,05787669 0,12638239 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,05787669 0,12623283 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,05787669 0,12608362 ! regulation of glucose transport GO:0010827 6 6 0,000 0,05787669 0,12593476 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,05787669 0,12578625 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,05787669 0,12563809 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,05787669 0,12549028 ! thymus development GO:0048538 6 6 0,000 0,05787669 0,12534282 ! lymph node development GO:0048535 6 6 0,000 0,05787669 0,1251957 ! organic cation transport GO:0015695 6 6 0,000 0,05787669 0,12504893 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,05787669 0,12490251 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,05787669 0,12475642 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,05787669 0,12461068 ! sperm-egg recognition GO:0035036 7 6 0,000 0,05787669 0,12446527 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,05787669 0,12432021 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,05787669 0,12417548 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,05787669 0,12403109 ! alditol metabolic process GO:0019400 6 6 0,000 0,05787669 0,12388704 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,05787669 0,12374332 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,05787669 0,12359993 ! maternal placenta development GO:0001893 6 6 0,000 0,05787669 0,12345687 ! regulation of embryonic development GO:0045995 6 6 0,000 0,05787669 0,12331415 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,05787669 0,12317175 ! negative regulation of transferase activity GO:0051348 40 40 1,000 0,05902725 0,12547546 ! cell-substrate adhesion GO:0031589 43 42 1,000 0,06434906 0,13663055 ! protein ubiquitination GO:0016567 43 42 1,000 0,06434906 0,13647333 ! response to protein stimulus GO:0051789 42 42 1,000 0,06434906 0,13631646 ! forebrain development GO:0030900 43 42 1,000 0,06434906 0,13615995 ! one-carbon metabolic process GO:0006730 42 42 1,000 0,06434906 0,13600381 ! regulation of response to stress GO:0080134 97 94 2,000 0,06555378 0,13839132 ! respiratory burst GO:0045730 7 7 0,000 0,0671965 0,14169697 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,0671965 0,14153503 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,0671965 0,14137346 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,0671965 0,14121226 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,0671965 0,14105143 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,0671965 0,14089096 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,0671965 0,14073085 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,0671965 0,14057111 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,0671965 0,14041174 ! gene silencing by RNA GO:0031047 7 7 0,000 0,0671965 0,14025272 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,0671965 0,14009406 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,0671965 0,13993577 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,0671965 0,13977782 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,0671965 0,13962024 ! axis specification GO:0009798 7 7 0,000 0,0671965 0,13946301 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,0671965 0,13930613 ! visual behavior GO:0007632 7 7 0,000 0,0671965 0,13914961 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,0671965 0,13899344 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,0671965 0,13883761 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,0671965 0,13868214 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,0671965 0,13852702 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,0671965 0,13837224 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,0671965 0,1382178 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,0671965 0,13806371 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,0671965 0,13790997 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,0671965 0,13775657 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,0671965 0,1376035 ! protein targeting to ER GO:0045047 8 7 0,000 0,0671965 0,13745078 ! endoderm development GO:0007492 7 7 0,000 0,0671965 0,13729839 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,0671965 0,13714635 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,0671965 0,13699464 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,0671965 0,13684326 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,0671965 0,13669222 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,0671965 0,13654151 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,0671965 0,13639114 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,0671965 0,13624109 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,0671965 0,13609138 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,0671965 0,13594199 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,0671965 0,13579293 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,0671965 0,1356442 ! response to X-ray GO:0010165 7 7 0,000 0,0671965 0,13549579 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,0671965 0,13534771 ! UV protection GO:0009650 7 7 0,000 0,0671965 0,13519995 ! DNA integration GO:0015074 7 7 0,000 0,0671965 0,13505251 ! myofibril assembly GO:0030239 7 7 0,000 0,0671965 0,13490539 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,0671965 0,1347586 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,0671965 0,13461212 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,0671965 0,13446596 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,0671965 0,13432012 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,0671965 0,1341746 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,0671965 0,13402939 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,0671965 0,13388449 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,0671965 0,13373991 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,0671965 0,13359563 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,0671965 0,13345167 ! axon cargo transport GO:0008088 7 7 0,000 0,0671965 0,13330802 ! eating behavior GO:0042755 7 7 0,000 0,0671965 0,13316468 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,0671965 0,13302165 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,0671965 0,13287892 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,0671965 0,1327365 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,0671965 0,13259438 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,0671965 0,13245257 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,0671965 0,13231106 ! induction of an organ GO:0001759 7 7 0,000 0,0671965 0,13216985 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,0671965 0,13202895 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,0671965 0,13188834 ! intracellular lipid transport GO:0032365 7 7 0,000 0,0671965 0,13174803 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,0671965 0,13160803 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,0671965 0,13146831 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,0671965 0,1313289 ! natural killer cell activation GO:0030101 7 7 0,000 0,0671965 0,13118978 ! response to gamma radiation GO:0010332 8 7 0,000 0,0671965 0,13105095 ! NADP metabolic process GO:0006739 7 7 0,000 0,0671965 0,13091242 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,0671965 0,13077418 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,0671965 0,13063624 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,0671965 0,13049858 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,0671965 0,13036121 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,0671965 0,13022413 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,0671965 0,13008734 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,0671965 0,12995084 ! cell-cell recognition GO:0009988 8 7 0,000 0,0671965 0,12981462 ! hormone catabolic process GO:0042447 7 7 0,000 0,0671965 0,12967869 ! dopamine metabolic process GO:0042417 7 7 0,000 0,0671965 0,12954305 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,0671965 0,12940768 ! oxygen transport GO:0015671 7 7 0,000 0,0671965 0,1292726 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,0671965 0,1291378 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,0671965 0,12900328 ! regulation of axon extension GO:0030516 7 7 0,000 0,0671965 0,12886904 ! adult feeding behavior GO:0008343 7 7 0,000 0,0671965 0,12873509 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,0671965 0,1286014 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,0671965 0,128468 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,0671965 0,12833487 ! response to cold GO:0009409 7 7 0,000 0,0671965 0,12820202 ! protein import into nucleus GO:0006606 44 44 1,000 0,06982641 0,13308177 ! positive regulation of lymphocyte activation GO:0051251 44 44 1,000 0,06982641 0,13294429 ! amine biosynthetic process GO:0009309 46 45 1,000 0,07262091 0,13812212 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,07262091 0,13797973 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,07262091 0,13783763 ! nuclear import GO:0051170 45 45 1,000 0,07262091 0,13769582 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 0,07545132 0,14291551 ! regulation of membrane potential GO:0042391 46 46 1,000 0,07545132 0,14276878 ! response to hormone stimulus GO:0009725 102 100 2,000 0,07589815 0,14346696 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 2,000 0,07589815 0,14331996 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,07642546 0,14416799 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,07642546 0,14402058 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,07642546 0,14387347 ! superoxide anion generation GO:0042554 8 8 0,000 0,07642546 0,14372666 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,07642546 0,14358015 ! cGMP metabolic process GO:0046068 8 8 0,000 0,07642546 0,14343394 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,07642546 0,14328802 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,07642546 0,1431424 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,07642546 0,14299708 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,07642546 0,14285205 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,07642546 0,14270732 ! zinc ion transport GO:0006829 8 8 0,000 0,07642546 0,14256288 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,07642546 0,14241873 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,07642546 0,14227487 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,07642546 0,14213131 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,07642546 0,14198803 ! lipid localization GO:0010876 8 8 0,000 0,07642546 0,14184504 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,07642546 0,14170234 ! response to cAMP GO:0051591 8 8 0,000 0,07642546 0,14155992 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,07642546 0,1414178 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,07642546 0,14127595 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,07642546 0,14113439 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,07642546 0,14099312 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,07642546 0,14085212 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,07642546 0,14071141 ! sensory perception of taste GO:0050909 8 8 0,000 0,07642546 0,14057098 ! organelle fusion GO:0048284 8 8 0,000 0,07642546 0,14043083 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,07642546 0,14029096 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,07642546 0,14015137 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,07642546 0,14001205 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,07642546 0,13987301 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,07642546 0,13973425 ! sperm motility GO:0030317 8 8 0,000 0,07642546 0,13959576 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,07642546 0,13945755 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,07642546 0,13931961 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,07642546 0,13918194 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,07642546 0,13904455 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,07642546 0,13890742 ! Golgi organization GO:0007030 8 8 0,000 0,07642546 0,13877057 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,07642546 0,13863398 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,07642546 0,13849766 ! fructose metabolic process GO:0006000 8 8 0,000 0,07642546 0,13836162 ! mannose metabolic process GO:0006013 9 8 0,000 0,07642546 0,13822583 ! NAD metabolic process GO:0019674 8 8 0,000 0,07642546 0,13809032 ! sex determination GO:0007530 8 8 0,000 0,07642546 0,13795507 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,07642546 0,13782008 ! plasma membrane fusion GO:0045026 8 8 0,000 0,07642546 0,13768536 ! response to fungus GO:0009620 8 8 0,000 0,07642546 0,1375509 ! stem cell differentiation GO:0048863 8 8 0,000 0,07642546 0,13741671 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,07642546 0,13728277 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,07642546 0,1371491 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,07642546 0,13701569 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,07642546 0,13688253 ! regulation of vasodilation GO:0042312 8 8 0,000 0,07642546 0,13674964 ! vasoconstriction GO:0042310 8 8 0,000 0,07642546 0,136617 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,07642546 0,13648462 ! muscle cell development GO:0055001 8 8 0,000 0,07642546 0,13635249 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,07642546 0,13622062 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,07642546 0,13608901 ! sensory perception of pain GO:0019233 8 8 0,000 0,07642546 0,13595765 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,07642546 0,13582654 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,07642546 0,13569569 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,07642546 0,13556509 ! chromatin silencing GO:0006342 8 8 0,000 0,07642546 0,13543473 ! tissue regeneration GO:0042246 8 8 0,000 0,07642546 0,13530463 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,07642546 0,13517478 ! T cell homeostasis GO:0043029 8 8 0,000 0,07642546 0,13504518 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,07642546 0,13491583 ! water homeostasis GO:0030104 8 8 0,000 0,07642546 0,13478672 ! cofactor transport GO:0051181 8 8 0,000 0,07642546 0,13465786 ! acid secretion GO:0046717 8 8 0,000 0,07642546 0,13452925 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,07642546 0,13440088 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,07642546 0,13427276 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,07642546 0,13414488 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,07642546 0,13401724 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,07642546 0,13388985 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,07642546 0,1337627 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 0,07642546 0,13363579 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,07642546 0,13350912 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,07642546 0,13338269 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,07642546 0,1332565 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,07642546 0,13313055 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,07642546 0,13300484 ! developmental induction GO:0031128 8 8 0,000 0,07642546 0,13287936 GO:0045168|cell-cell signaling involved in cell fate specification, ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,07642546 0,13275412 ! actin filament polymerization GO:0030041 9 8 0,000 0,07642546 0,13262912 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,07642546 0,13250435 ! peptide hormone processing GO:0016486 8 8 0,000 0,07642546 0,13237982 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,07642546 0,13225552 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,07642546 0,13213145 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 1,000 0,07831669 0,13527428 ! sex differentiation GO:0007548 47 47 1,000 0,07831669 0,13514762 ! rhythmic process GO:0048511 47 47 1,000 0,07831669 0,1350212 ! actin filament organization GO:0007015 50 48 1,000 0,08121607 0,13988899 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,08121607 0,13975838 ! ossification GO:0001503 50 49 1,000 0,08414854 0,14466955 GO:0060348|bone development, ! cellular lipid catabolic process GO:0044242 50 49 1,000 0,08414854 0,14453472 ! positive regulation of cell activation GO:0050867 49 49 1,000 0,08414854 0,14440014 GO:0002696|positive regulation of leukocyte activation, ! lactation GO:0007595 10 9 0,000 0,08556444 0,14669327 ! embryonic pattern specification GO:0009880 10 9 0,000 0,08556444 0,14655694 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,08556444 0,14642086 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,08556444 0,14628503 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,08556444 0,14614946 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,08556444 0,14601413 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,08556444 0,14587906 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,08556444 0,14574424 ! copper ion transport GO:0006825 9 9 0,000 0,08556444 0,14560966 ! lipid phosphorylation GO:0046834 9 9 0,000 0,08556444 0,14547534 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,08556444 0,14534126 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,08556444 0,14520743 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,08556444 0,14507384 ! RNA polyadenylation GO:0043631 9 9 0,000 0,08556444 0,1449405 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,08556444 0,1448074 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,08556444 0,14467455 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,08556444 0,14454195 ! phospholipid efflux GO:0033700 9 9 0,000 0,08556444 0,14440958 ! response to alkaloid GO:0043279 10 9 0,000 0,08556444 0,14427746 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,08556444 0,14414558 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,08556444 0,14401394 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,08556444 0,14388254 ! response to ethanol GO:0045471 9 9 0,000 0,08556444 0,14375138 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,08556444 0,14362046 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,08556444 0,14348978 ! methionine metabolic process GO:0006555 9 9 0,000 0,08556444 0,14335933 ! glutamine metabolic process GO:0006541 9 9 0,000 0,08556444 0,14322912 ! cerebral cortex development GO:0021987 9 9 0,000 0,08556444 0,14309915 ! response to osmotic stress GO:0006970 9 9 0,000 0,08556444 0,14296941 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,08556444 0,14283991 ! central nervous system neuron development GO:0021954 10 9 0,000 0,08556444 0,14271065 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,08556444 0,14258161 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,08556444 0,14245281 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,08556444 0,14232425 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,08556444 0,14219591 ! L-glutamate transport GO:0015813 9 9 0,000 0,08556444 0,14206781 GO:0015800|acidic amino acid transport, ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,08556444 0,14193993 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,08556444 0,14181229 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,08556444 0,14168487 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,08556444 0,14155769 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,08556444 0,14143073 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,08556444 0,141304 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,08556444 0,1411775 ! regulation of cellular pH GO:0030641 9 9 0,000 0,08556444 0,14105122 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,08556444 0,14092517 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,08556444 0,14079934 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,08556444 0,14067374 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,08556444 0,14054836 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,08556444 0,14042321 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,08556444 0,14029828 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,08556444 0,14017357 ! purine base metabolic process GO:0006144 9 9 0,000 0,08556444 0,14004908 ! gas transport GO:0015669 9 9 0,000 0,08556444 0,13992481 ! cholesterol efflux GO:0033344 9 9 0,000 0,08556444 0,13980077 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,08556444 0,13967694 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,08556444 0,13955333 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,08556444 0,13942994 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,08556444 0,13930677 ! actin filament-based movement GO:0030048 9 9 0,000 0,08556444 0,13918382 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,08556444 0,13906108 ! regulation of DNA metabolic process GO:0051052 51 50 1,000 0,08711317 0,14145337 ! chromatin assembly GO:0031497 50 50 1,000 0,08711317 0,14132885 GO:0006334|nucleosome assembly, ! T cell activation GO:0042110 51 50 1,000 0,08711317 0,14120455 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,09010908 0,14593236 ! positive regulation of immune response GO:0050778 51 51 1,000 0,09010908 0,14580424 ! protein-DNA complex assembly GO:0065004 51 51 1,000 0,09010908 0,14567634 ! cell fate commitment GO:0045165 52 52 1,000 0,09313537 0,15043688 ! regulation of body fluid levels GO:0050878 55 52 1,000 0,09313537 0,15030515 ! response to light stimulus GO:0009416 53 52 1,000 0,09313537 0,15017365 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,0946143 0,15242497 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,0946143 0,15229185 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,0946143 0,15215896 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,0946143 0,1520263 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,0946143 0,15189387 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! neuron maturation GO:0042551 10 10 0,000 0,0946143 0,15176167 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,0946143 0,15162971 ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,0946143 0,15149797 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,0946143 0,15136646 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,0946143 0,15123518 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,0946143 0,15110413 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,0946143 0,1509733 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,0946143 0,1508427 ! cAMP metabolic process GO:0046058 10 10 0,000 0,0946143 0,15071233 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,0946143 0,15058218 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,0946143 0,15045226 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,0946143 0,15032256 ! glial cell development GO:0021782 10 10 0,000 0,0946143 0,15019308 ! phototransduction GO:0007602 11 10 0,000 0,0946143 0,15006382 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,0946143 0,14993479 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,0946143 0,14980598 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,0946143 0,14967739 ! fat cell differentiation GO:0045444 10 10 0,000 0,0946143 0,14954903 ! myoblast differentiation GO:0045445 10 10 0,000 0,0946143 0,14942088 ! centrosome cycle GO:0007098 10 10 0,000 0,0946143 0,14929295 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,0946143 0,14916524 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,0946143 0,14903775 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,0946143 0,14891047 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,0946143 0,14878342 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,0946143 0,14865658 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,0946143 0,14852995 ! protein polyubiquitination GO:0000209 10 10 0,000 0,0946143 0,14840354 ! glutamate metabolic process GO:0006536 11 10 0,000 0,0946143 0,14827735 ! plasma membrane organization GO:0007009 10 10 0,000 0,0946143 0,14815137 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,0946143 0,14802561 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,0946143 0,14790005 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,0946143 0,14777472 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,0946143 0,14764959 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,0946143 0,14752467 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,0946143 0,14739997 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,0946143 0,14727548 ! regulation of protein binding GO:0043393 11 10 0,000 0,0946143 0,14715119 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,0946143 0,14702712 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,0946143 0,14690326 GO:0070585|protein localization in mitochondrion, ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,0946143 0,1467796 ! protein export from nucleus GO:0006611 10 10 0,000 0,0946143 0,14665615 ! negative regulation of immune response GO:0050777 10 10 0,000 0,0946143 0,14653291 ! cytolysis GO:0019835 10 10 0,000 0,0946143 0,14640988 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,0946143 0,14628705 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,0946143 0,14616443 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,0946143 0,14604201 ! mRNA splice site selection GO:0006376 11 10 0,000 0,0946143 0,1459198 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,0946143 0,1457978 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,0946143 0,14567599 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,0946143 0,14555439 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,0946143 0,145433 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,0946143 0,1453118 ! regulation of epidermis development GO:0045682 10 10 0,000 0,0946143 0,14519081 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,0946143 0,14507002 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,0946143 0,14494943 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,0946143 0,14482904 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,0946143 0,14470885 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,0946143 0,14458886 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,0946143 0,14446907 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,0946143 0,14434947 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,0946143 0,14423008 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,0946143 0,14411088 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,0946143 0,14399188 ! protein stabilization GO:0050821 10 10 0,000 0,0946143 0,14387307 ! hormone metabolic process GO:0042445 55 54 1,000 0,09927563 0,15083675 ! sulfur metabolic process GO:0006790 55 54 1,000 0,09927563 0,15071251 ! nucleosome organization GO:0034728 55 55 1,000 0,1023879 0,15530938 ! in utero embryonic development GO:0001701 55 55 1,000 0,1023879 0,15518166 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,1023879 0,15505414 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,1023879 0,15492684 ! protein secretion GO:0009306 11 11 0,000 0,10357591 0,1565959 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,10357591 0,15646754 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,10357591 0,1563394 ! negative regulation of defense response GO:0031348 11 11 0,000 0,10357591 0,15621146 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,10357591 0,15608373 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,10357591 0,15595621 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,10357591 0,1558289 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,10357591 0,1557018 ! skin development GO:0043588 11 11 0,000 0,10357591 0,1555749 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,10357591 0,15544821 ! signal complex assembly GO:0007172 11 11 0,000 0,10357591 0,15532173 ! microtubule-based transport GO:0010970 11 11 0,000 0,10357591 0,15519545 ! endothelial cell migration GO:0043542 11 11 0,000 0,10357591 0,15506938 ! peroxisomal transport GO:0043574 11 11 0,000 0,10357591 0,15494351 ! protein amino acid methylation GO:0006479 11 11 0,000 0,10357591 0,15481784 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,10357591 0,15469238 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,10357591 0,15456713 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,10357591 0,15444207 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,10357591 0,15431722 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,10357591 0,15419257 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,10357591 0,15406812 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,10357591 0,15394387 ! smooth muscle contraction GO:0006939 11 11 0,000 0,10357591 0,15381982 ! cellular response to starvation GO:0009267 11 11 0,000 0,10357591 0,15369598 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,10357591 0,15357233 ! digestive system process GO:0022600 11 11 0,000 0,10357591 0,15344888 ! mitotic spindle organization GO:0007052 11 11 0,000 0,10357591 0,15332562 ! fucose metabolic process GO:0006004 11 11 0,000 0,10357591 0,15320257 ! membrane budding GO:0006900 11 11 0,000 0,10357591 0,15307971 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,10357591 0,15295705 ! monoamine transport GO:0015844 11 11 0,000 0,10357591 0,15283459 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,10357591 0,15271232 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,10357591 0,15259025 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,10357591 0,15246837 ! body fluid secretion GO:0007589 11 11 0,000 0,10357591 0,15234669 ! intermediate filament-based process GO:0045103 11 11 0,000 0,10357591 0,1522252 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,10357591 0,15210391 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,10357591 0,1519828 ! membrane depolarization GO:0051899 11 11 0,000 0,10357591 0,1518619 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,10357591 0,15174118 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,10357591 0,15162065 ! oogenesis GO:0048477 11 11 0,000 0,10357591 0,15150032 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,10357591 0,15138018 ! vitamin transport GO:0051180 11 11 0,000 0,10357591 0,15126022 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,10357591 0,15114046 ! steroid catabolic process GO:0006706 11 11 0,000 0,10357591 0,15102089 ! endocrine process GO:0050886 11 11 0,000 0,10357591 0,1509015 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,10357591 0,15078231 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,10357591 0,1506633 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,10357591 0,15054448 ! extracellular structure organization GO:0043062 56 56 1,000 0,10552715 0,15325968 ! translational initiation GO:0006413 12 12 0,000 0,1124501 0,16318547 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,1124501 0,16305707 ! iron ion transport GO:0006826 13 12 0,000 0,1124501 0,16292888 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,1124501 0,1628009 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,1124501 0,16267311 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,1124501 0,16254552 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,1124501 0,16241814 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,1124501 0,16229095 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,1124501 0,16216396 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,1124501 0,16203717 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,1124501 0,16191058 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,1124501 0,16178419 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,1124501 0,16165799 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,1124501 0,16153199 ! actomyosin structure organization GO:0031032 12 12 0,000 0,1124501 0,16140619 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,1124501 0,16128058 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,1124501 0,16115516 ! retinoid metabolic process GO:0001523 12 12 0,000 0,1124501 0,16102995 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,1124501 0,16090492 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,1124501 0,16078009 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,1124501 0,16065546 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,1124501 0,16053102 ! vacuolar transport GO:0007034 12 12 0,000 0,1124501 0,16040677 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,1124501 0,16028271 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,1124501 0,16015884 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,1124501 0,16003517 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,1124501 0,15991168 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,1124501 0,15978839 ! male gonad development GO:0008584 12 12 0,000 0,1124501 0,15966529 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,1124501 0,15954237 ! renal system process GO:0003014 12 12 0,000 0,1124501 0,15941965 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,1124501 0,15929711 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,1124501 0,15917476 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,1124501 0,1590526 ! pallium development GO:0021543 13 12 0,000 0,1124501 0,15893063 ! cell fate determination GO:0001709 12 12 0,000 0,1124501 0,15880884 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,1124501 0,15868724 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,1124501 0,15856583 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,1124501 0,1584446 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,1124501 0,15832356 ! detection of light stimulus GO:0009583 13 12 0,000 0,1124501 0,1582027 ! synaptogenesis GO:0007416 12 12 0,000 0,1124501 0,15808203 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,1124501 0,15796154 ! heme biosynthetic process GO:0006783 12 12 0,000 0,1124501 0,15784124 ! spermatid differentiation GO:0048515 13 12 0,000 0,1124501 0,15772111 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,1124501 0,15760117 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,1124501 0,15748141 ! neural tube closure GO:0001843 13 12 0,000 0,1124501 0,15736184 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,1124501 0,15724244 ! negative regulation of translation GO:0017148 12 12 0,000 0,1124501 0,15712323 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,1124501 0,1570042 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,1124501 0,15688535 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,12123773 0,1690175 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,12123773 0,16888974 ! phenol metabolic process GO:0018958 13 13 0,000 0,12123773 0,16876218 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,12123773 0,16863482 ! gluconeogenesis GO:0006094 13 13 0,000 0,12123773 0,16850764 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,12123773 0,16838066 GO:0019692|deoxyribose phosphate metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,12123773 0,16825386 ! regeneration GO:0031099 13 13 0,000 0,12123773 0,16812726 ! keratinization GO:0031424 13 13 0,000 0,12123773 0,16800085 ! post-embryonic development GO:0009791 14 13 0,000 0,12123773 0,16787463 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,12123773 0,1677486 ! patterning of blood vessels GO:0001569 13 13 0,000 0,12123773 0,16762275 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,12123773 0,1674971 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,12123773 0,16737163 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,12123773 0,16724636 ! autophagy GO:0006914 13 13 0,000 0,12123773 0,16712126 ! receptor metabolic process GO:0043112 14 13 0,000 0,12123773 0,16699636 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,12123773 0,16687164 ! cell aging GO:0007569 13 13 0,000 0,12123773 0,16674711 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,12123773 0,16662277 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,12123773 0,16649861 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,12123773 0,16637463 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,12123773 0,16625084 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,12123773 0,16612723 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,12123773 0,16600381 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,12123773 0,16588057 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,12123773 0,16575752 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,12123773 0,16563464 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,12123773 0,16551195 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,12123773 0,16538944 ! vasodilation GO:0042311 14 13 0,000 0,12123773 0,16526711 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,12123773 0,16514496 GO:0006664|glycolipid metabolic process, ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,12123773 0,16502299 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,12123773 0,1649012 ! immunoglobulin production GO:0002377 13 13 0,000 0,12123773 0,16477959 GO:0002440|production of molecular mediator of immune response, ! cell-cell junction organization GO:0045216 13 13 0,000 0,12123773 0,16465817 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,12123773 0,16453691 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,12123773 0,16441584 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,12123773 0,16429495 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,12123773 0,16417423 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,12123773 0,16405369 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,12123773 0,16393333 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,12123773 0,16381315 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,12123773 0,16369314 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,12123773 0,1635733 ! blastocyst development GO:0001824 13 13 0,000 0,12123773 0,16345364 ! telomere organization GO:0032200 13 13 0,000 0,12123773 0,16333416 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,12123773 0,16321485 ! regulation of amine transport GO:0051952 13 13 0,000 0,12123773 0,16309572 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,12123773 0,16297675 ! protein tetramerization GO:0051262 13 13 0,000 0,12123773 0,16285797 ! carboxylic acid catabolic process GO:0046395 63 61 1,000 0,12159995 0,16322557 GO:0016054|organic acid catabolic process, ! axonogenesis GO:0007409 66 62 1,000 0,12488437 0,1675123 ! protein import GO:0017038 62 62 1,000 0,12488437 0,16739047 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,12993961 0,17403975 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,12993961 0,17391336 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,12993961 0,17378716 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,12993961 0,17366113 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,12993961 0,17353529 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,12993961 0,17340963 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,12993961 0,17328415 ! vesicle docking GO:0048278 14 14 0,000 0,12993961 0,17315886 ! superoxide metabolic process GO:0006801 15 14 0,000 0,12993961 0,17303374 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,12993961 0,17290881 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,12993961 0,17278406 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,12993961 0,17265948 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,12993961 0,17253509 ! hair cycle GO:0042633 14 14 0,000 0,12993961 0,17241087 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,12993961 0,17228684 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,12993961 0,17216298 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,12993961 0,1720393 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,12993961 0,17191579 ! lysosome organization GO:0007040 14 14 0,000 0,12993961 0,17179247 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,12993961 0,17166932 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,12993961 0,17154635 ! primary neural tube formation GO:0014020 15 14 0,000 0,12993961 0,17142355 ! peptide cross-linking GO:0018149 14 14 0,000 0,12993961 0,17130093 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,12993961 0,17117849 ! base-excision repair GO:0006284 14 14 0,000 0,12993961 0,17105622 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,12993961 0,17093412 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,12993961 0,1708122 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,12993961 0,17069045 ! formation of primary germ layer GO:0001704 14 14 0,000 0,12993961 0,17056888 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,12993961 0,17044747 ! collagen fibril organization GO:0030199 14 14 0,000 0,12993961 0,17032625 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,12993961 0,17020519 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,12993961 0,17008431 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,12993961 0,16996359 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,12993961 0,16984305 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,12993961 0,16972268 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,12993961 0,16960248 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,13486389 0,17590527 ! DNA packaging GO:0006323 66 66 1,000 0,13823009 0,18016836 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,13823009 0,18004103 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,13855658 0,18033882 ! positive regulation of ossification GO:0045778 15 15 0,000 0,13855658 0,18021156 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,13855658 0,18008447 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,13855658 0,17995756 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,13855658 0,17983083 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,13855658 0,17970428 ! response to vitamin GO:0033273 15 15 0,000 0,13855658 0,1795779 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,13855658 0,1794517 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,13855658 0,17932568 ! ovarian follicle development GO:0001541 15 15 0,000 0,13855658 0,17919984 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,13855658 0,17907418 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,13855658 0,17894869 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,13855658 0,17882337 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,13855658 0,17869823 ! heme metabolic process GO:0042168 15 15 0,000 0,13855658 0,17857327 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,13855658 0,17844848 ! chromosome condensation GO:0030261 15 15 0,000 0,13855658 0,17832387 ! response to starvation GO:0042594 15 15 0,000 0,13855658 0,17819942 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,13855658 0,17807516 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,13855658 0,17795106 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,13855658 0,17782714 GO:0030500|regulation of bone mineralization, ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,13855658 0,17770339 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,13855658 0,17757982 ! phospholipid transport GO:0015914 15 15 0,000 0,13855658 0,17745641 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,13855658 0,17733318 GO:0046496|nicotinamide nucleotide metabolic process, ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,13855658 0,17721011 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,13855658 0,17708722 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,13855658 0,1769645 ! protein homooligomerization GO:0051260 15 15 0,000 0,13855658 0,17684195 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,14161498 0,18062035 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 1,000 0,14161498 0,18049544 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,14161498 0,1803707 ! chromatin assembly or disassembly GO:0006333 68 68 1,000 0,14501786 0,18457729 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,14708945 0,18708479 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,14708945 0,18695576 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,14708945 0,18682692 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,14708945 0,18669825 ! learning GO:0007612 16 16 0,000 0,14708945 0,18656976 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,14708945 0,18644144 ! vacuole organization GO:0007033 16 16 0,000 0,14708945 0,1863133 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,14708945 0,18618534 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,14708945 0,18605755 ! vesicle targeting GO:0006903 17 16 0,000 0,14708945 0,18592994 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,14708945 0,1858025 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,14708945 0,18567524 ! positive regulation of cell development GO:0010720 16 16 0,000 0,14708945 0,18554815 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,14708945 0,18542124 ! pentose metabolic process GO:0019321 16 16 0,000 0,14708945 0,1852945 ! fatty acid transport GO:0015908 16 16 0,000 0,14708945 0,18516793 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,14708945 0,18504154 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,14708945 0,18491532 ! cofactor catabolic process GO:0051187 16 16 0,000 0,14708945 0,18478927 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,14708945 0,18466339 ! polyol metabolic process GO:0019751 16 16 0,000 0,14708945 0,18453768 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,14708945 0,18441215 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,14708945 0,18428678 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,14708945 0,18416159 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,14708945 0,18403656 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,14708945 0,18391171 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,14708945 0,18378702 ! regulation of coagulation GO:0050818 17 16 0,000 0,14708945 0,1836625 ! sensory perception of sound GO:0007605 71 69 1,000 0,14843807 0,18522096 GO:0050954|sensory perception of mechanical stimulus, ! cell part morphogenesis GO:0032990 75 70 1,000 0,15187495 0,18938128 ! carboxylic acid biosynthetic process GO:0046394 70 70 1,000 0,15187495 0,18925323 GO:0016053|organic acid biosynthetic process, ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,15553903 0,19368813 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,15553903 0,19355735 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,15553903 0,19342674 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,15553903 0,19329631 ! sensory perception of smell GO:0007608 17 17 0,000 0,15553903 0,19316606 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,15553903 0,19303598 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,15553903 0,19290608 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,15553903 0,19277635 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,15553903 0,19264679 ! response to toxin GO:0009636 18 17 0,000 0,15553903 0,19251741 ! negative regulation of cell development GO:0010721 18 17 0,000 0,15553903 0,19238821 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,15553903 0,19225918 GO:0002764|immune response-regulating signal transduction, ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,15553903 0,19213032 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,15553903 0,19200163 ! adult locomotory behavior GO:0008344 17 17 0,000 0,15553903 0,19187311 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,15553903 0,19174477 ! liver development GO:0001889 17 17 0,000 0,15553903 0,1916166 ! gene silencing GO:0016458 17 17 0,000 0,15553903 0,1914886 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,15879612 0,19536799 ! sensory organ development GO:0007423 72 72 1,000 0,15879612 0,19523766 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,16390612 0,20138599 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,16390612 0,20125182 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,16390612 0,20111783 ! meiosis I GO:0007127 18 18 0,000 0,16390612 0,20098402 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,16390612 0,20085039 ! membrane docking GO:0022406 18 18 0,000 0,16390612 0,20071693 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,16390612 0,20058365 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,16390612 0,20045055 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,16390612 0,20031763 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,16390612 0,20018488 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,16390612 0,2000523 ! ceramide metabolic process GO:0006672 18 18 0,000 0,16390612 0,19991991 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,16390612 0,19978768 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! hexose biosynthetic process GO:0019319 18 18 0,000 0,16390612 0,19965564 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,16390612 0,19952376 ! B cell differentiation GO:0030183 18 18 0,000 0,16390612 0,19939207 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,16390612 0,19926054 ! BMP signaling pathway GO:0030509 18 18 0,000 0,16390612 0,19912919 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,16390612 0,19899801 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,16390612 0,198867 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,16390612 0,19873617 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,16390612 0,19860551 ! coenzyme metabolic process GO:0006732 75 74 1,000 0,16577631 0,20073964 ! response to oxidative stress GO:0006979 76 75 1,000 0,169287 0,20485617 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,17219152 0,20823423 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,17219152 0,20809768 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,17219152 0,20796131 ! regulation of pH GO:0006885 19 19 0,000 0,17219152 0,20782512 ! feeding behavior GO:0007631 19 19 0,000 0,17219152 0,20768911 ! peroxisome organization GO:0007031 19 19 0,000 0,17219152 0,20755328 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,17219152 0,20741762 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,17219152 0,20728214 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,17219152 0,20714684 ! regulation of protein stability GO:0031647 19 19 0,000 0,17219152 0,20701172 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,17219152 0,20687677 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,17219152 0,206742 ! vesicle localization GO:0051648 20 19 0,000 0,17219152 0,2066074 ! regulation of muscle development GO:0048634 21 20 0,000 0,180396 0,21631089 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,180396 0,21617024 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,180396 0,21602978 ! negative regulation of binding GO:0051100 21 20 0,000 0,180396 0,2158895 ! organic ether metabolic process GO:0018904 20 20 0,000 0,180396 0,2157494 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,180396 0,21560949 ! phagocytosis GO:0006909 21 20 0,000 0,180396 0,21546975 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,180396 0,2153302 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,180396 0,21519083 ! chromatin remodeling GO:0006338 20 20 0,000 0,180396 0,21505164 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,180396 0,21491262 ! female gamete generation GO:0007292 20 20 0,000 0,180396 0,21477379 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,180396 0,21463514 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,180396 0,21449666 ! RNA modification GO:0009451 20 20 0,000 0,180396 0,21435837 ! single fertilization GO:0007338 21 20 0,000 0,180396 0,21422025 ! nuclear transport GO:0051169 79 79 1,000 0,18345328 0,21771049 GO:0006913|nucleocytoplasmic transport, ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,18852036 0,2235798 ! mRNA catabolic process GO:0006402 21 21 0,000 0,18852036 0,22343602 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,18852036 0,22329243 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,18852036 0,22314901 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,18852036 0,22300579 ! Notch signaling pathway GO:0007219 22 21 0,000 0,18852036 0,22286274 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,18852036 0,22271988 ! ear morphogenesis GO:0042471 21 21 0,000 0,18852036 0,2225772 ! organic anion transport GO:0015711 21 21 0,000 0,18852036 0,22243471 ! cholesterol transport GO:0030301 21 21 0,000 0,18852036 0,2222924 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,18852036 0,22215027 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,18852036 0,22200832 GO:0032313|regulation of Rab GTPase activity, ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,18852036 0,22186655 ! regulation of proteolysis GO:0030162 21 21 0,000 0,18852036 0,22172496 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,18852036 0,22158356 ! MAPKKK cascade GO:0000165 82 81 1,000 0,19060256 0,22388815 ! lymphocyte activation GO:0046649 82 81 1,000 0,19060256 0,22374555 ! lipid catabolic process GO:0016042 82 81 1,000 0,19060256 0,22360313 ! RNA export from nucleus GO:0006405 22 22 0,000 0,19656535 0,23045162 ! sister chromatid segregation GO:0000819 22 22 0,000 0,19656535 0,23030511 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,19656535 0,23015879 ! regulation of ion transport GO:0043269 22 22 0,000 0,19656535 0,23001266 ! hormone-mediated signaling GO:0009755 22 22 0,000 0,19656535 0,22986671 ! ovulation cycle process GO:0022602 22 22 0,000 0,19656535 0,22972095 ! spindle organization GO:0007051 22 22 0,000 0,19656535 0,22957537 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,19656535 0,22942998 ! male sex differentiation GO:0046661 22 22 0,000 0,19656535 0,22928477 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,19656535 0,22913975 ! biopolymer methylation GO:0043414 22 22 0,000 0,19656535 0,22899491 GO:0032259|methylation, ! detection of external stimulus GO:0009581 23 22 0,000 0,19656535 0,22885025 ! neuron migration GO:0001764 22 22 0,000 0,19656535 0,22870577 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,19656535 0,22856148 ! aerobic respiration GO:0009060 22 22 0,000 0,19656535 0,22841736 ! cytokine production GO:0001816 22 22 0,000 0,19656535 0,22827343 ! cytokinesis GO:0000910 23 22 0,000 0,19656535 0,22812969 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,19656535 0,22798612 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,2013969 0,23344308 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,20453175 0,23692773 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,20453175 0,2367789 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,20453175 0,23663026 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,20453175 0,23648181 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,20453175 0,23633355 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,20453175 0,23618547 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,20453175 0,23603758 ! positive regulation of growth GO:0045927 23 23 0,000 0,20453175 0,23588987 ! female gonad development GO:0008585 23 23 0,000 0,20453175 0,23574235 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,20453175 0,23559501 ! lipid homeostasis GO:0055088 23 23 0,000 0,20453175 0,23544785 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,20453175 0,23530088 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,20453175 0,23515409 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,20501171 0,23555897 ! mitochondrial transport GO:0006839 24 24 0,000 0,21242031 0,24391939 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,21242031 0,24376751 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,21242031 0,24361582 ! T cell differentiation GO:0030217 24 24 0,000 0,21242031 0,24346432 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,21242031 0,243313 ! ovulation cycle GO:0042698 24 24 0,000 0,21242031 0,24316188 ! fertilization GO:0009566 25 24 0,000 0,21242031 0,24301094 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,21242031 0,24286019 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,22023177 0,25163494 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,22023177 0,25147903 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,22023177 0,25132332 ! cellular component disassembly GO:0022411 26 25 0,000 0,22023177 0,2511678 ! endosome transport GO:0016197 25 25 0,000 0,22023177 0,25101247 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,22023177 0,25085733 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,22023177 0,25070238 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,22023177 0,25054763 ! excretion GO:0007588 25 25 0,000 0,22023177 0,25039306 ! gastrulation GO:0007369 25 25 0,000 0,22023177 0,25023869 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,22023177 0,25008451 ! regulation of endocytosis GO:0030100 25 25 0,000 0,22023177 0,24993052 ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 0,22318862 0,25313023 ! DNA replication GO:0006260 91 91 1,000 0,22684124 0,25711464 ! glycolysis GO:0006096 26 26 0,000 0,22796689 0,2582317 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,22796689 0,25807308 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,22796689 0,25791466 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,22796689 0,25775643 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,22796689 0,25759839 ! double-strand break repair GO:0006302 27 26 0,000 0,22796689 0,25744055 ! germ cell development GO:0007281 27 26 0,000 0,22796689 0,2572829 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,22796689 0,25712545 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,22796689 0,25696818 ! fatty acid metabolic process GO:0006631 93 92 1,000 0,23049855 0,2596631 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,23049855 0,25950448 ! chloride transport GO:0006821 27 27 0,000 0,2356264 0,26511566 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,2356264 0,26495391 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,2356264 0,26479235 ! activation of caspase activity GO:0006919 27 27 0,000 0,2356264 0,26463099 ! inner ear development GO:0048839 27 27 0,000 0,2356264 0,26446982 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,2356264 0,26430886 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,2356264 0,26414808 ! epidermis development GO:0008544 94 94 1,000 0,23782546 0,26645126 ! cofactor metabolic process GO:0051186 95 94 1,000 0,23782546 0,26628938 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,24321102 0,27215416 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,24321102 0,27198902 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,24321102 0,27182408 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,24321102 0,27165934 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,24321102 0,27149479 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,24321102 0,27133045 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,24321102 0,27116631 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,25072147 0,27937103 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,25072147 0,27920222 ! antigen processing and presentation GO:0019882 29 29 0,000 0,25072147 0,27903362 ! tRNA processing GO:0008033 29 29 0,000 0,25072147 0,27886523 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,25072147 0,27869703 ! adult behavior GO:0030534 30 29 0,000 0,25072147 0,27852904 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,25072147 0,27836125 ! glycoprotein metabolic process GO:0009100 99 98 1,000 0,25251654 0,28018542 ! transition metal ion transport GO:0000041 31 30 0,000 0,25815848 0,28627322 ! RNA catabolic process GO:0006401 30 30 0,000 0,25815848 0,28610107 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,25815848 0,28592914 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,25815848 0,28575741 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,25815848 0,28558588 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,25815848 0,28541457 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,25815848 0,28524346 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,25815848 0,28507255 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,25815848 0,28490185 GO:0019724|B cell mediated immunity, ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,25815848 0,28473135 ! vesicle organization GO:0016050 30 30 0,000 0,25815848 0,28456105 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,25815848 0,28439096 ! establishment of organelle localization GO:0051656 31 30 0,000 0,25815848 0,28422108 ! membrane fusion GO:0006944 31 31 0,000 0,26552275 0,29215428 ! B cell activation GO:0042113 31 31 0,000 0,26552275 0,29197997 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,26552275 0,29180586 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,26552275 0,29163196 ! ion transmembrane transport GO:0034220 31 31 0,000 0,26552275 0,29145826 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,26552275 0,29128478 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,26552275 0,2911115 ! digestion GO:0007586 31 31 0,000 0,26552275 0,29093842 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,26552275 0,29076555 ! regulation of heart contraction GO:0008016 31 31 0,000 0,26552275 0,29059289 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,26552275 0,29042043 ! extracellular matrix organization GO:0030198 31 31 0,000 0,26552275 0,29024818 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,26552275 0,29007613 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,26552275 0,28990428 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,26552275 0,28973264 ! cell redox homeostasis GO:0045454 32 32 0,000 0,27281497 0,29751361 ! glucose catabolic process GO:0006007 32 32 0,000 0,27281497 0,29733767 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,27281497 0,29716194 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,27281497 0,29698641 ! nuclear export GO:0051168 32 32 0,000 0,27281497 0,2968111 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,27281497 0,29663599 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,28003585 0,30430783 ! amino acid transport GO:0006865 33 33 0,000 0,28003585 0,30412851 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,28003585 0,3039494 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,28003585 0,3037705 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,28003585 0,30359181 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,28003585 0,30341333 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,28003585 0,30323506 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,28003585 0,303057 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,28003585 0,30287915 ! regulation of actin filament length GO:0030832 34 34 0,000 0,28718607 0,31043046 ! ear development GO:0043583 34 34 0,000 0,28718607 0,3102485 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,28718607 0,31006675 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,28718607 0,30988521 ! secondary metabolic process GO:0019748 34 34 0,000 0,28718607 0,30970388 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,28718607 0,30952277 ! regulation of cellular component size GO:0032535 35 35 0,000 0,29426632 0,31696834 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,29426632 0,31678319 GO:0048609|reproductive process in a multicellular organism, ! inorganic anion transport GO:0015698 35 35 0,000 0,29426632 0,31659826 ! hydrogen transport GO:0006818 36 36 0,000 0,30127726 0,32395215 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,30127726 0,32376326 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,30127726 0,32357459 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,30127726 0,32338613 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,30127726 0,3231979 ! gonad development GO:0008406 36 36 0,000 0,30127726 0,32300988 ! activation of immune response GO:0002253 36 36 0,000 0,30127726 0,32282209 ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,30821957 0,33006895 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! response to drug GO:0042493 37 37 0,000 0,30821957 0,32987727 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,30821957 0,32968581 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,30821957 0,32949458 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,30821957 0,32930357 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,3150939 0,3364531 ! chromosome segregation GO:0007059 38 38 0,000 0,3150939 0,33625828 ! hexose catabolic process GO:0019320 38 38 0,000 0,3150939 0,33606369 ! regulation of neurological system process GO:0031644 38 38 0,000 0,3150939 0,33586932 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,32190092 0,34292682 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,32190092 0,34272871 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,32190092 0,34253083 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,32190092 0,34233317 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,32190092 0,34213575 ! protein oligomerization GO:0051259 39 39 0,000 0,32190092 0,34193855 ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,32864127 0,34889738 ! organelle localization GO:0051640 41 40 0,000 0,32864127 0,34869652 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,33531559 0,35557344 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,33531559 0,35536897 ! regulation of caspase activity GO:0043281 41 41 0,000 0,33531559 0,35516474 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,33531559 0,35496074 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,33531559 0,35475697 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,33531559 0,35455344 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,34192453 0,36133424 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,34192453 0,36112717 ! regulation of endopeptidase activity GO:0052548 42 42 0,000 0,34192453 0,36092034 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,34192453 0,36071375 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,34192453 0,36050739 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,34192453 0,36030127 ! mitochondrion organization GO:0007005 44 43 0,000 0,34846872 0,36698734 ! alcohol catabolic process GO:0046164 43 43 0,000 0,34846872 0,36677775 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,34846872 0,36656841 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,35494877 0,37317204 ! mRNA transport GO:0051028 44 44 0,000 0,35494877 0,37295929 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,35494877 0,37274677 ! vitamin metabolic process GO:0006766 44 44 0,000 0,35494877 0,3725345 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,36136531 0,37905309 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,36136531 0,37883747 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,36136531 0,3786221 ! protein processing GO:0016485 45 45 0,000 0,36136531 0,37840697 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,36771896 0,38484159 ! regulation of peptidase activity GO:0052547 46 46 0,000 0,36771896 0,38462318 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,36771896 0,38440501 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,36771896 0,3841871 ! regulation of blood pressure GO:0008217 48 47 0,000 0,37401031 0,39053881 ! amine transport GO:0015837 47 47 0,000 0,37401031 0,39031767 ! calcium ion transport GO:0006816 48 48 0,000 0,38023998 0,39659438 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,38023998 0,39637007 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,38023998 0,396146 ! DNA recombination GO:0006310 48 48 0,000 0,38023998 0,39592219 ! leukocyte differentiation GO:0002521 50 49 0,000 0,38640855 0,40211799 ! divalent metal ion transport GO:0070838 49 49 0,000 0,38640855 0,40189106 ! response to nutrient GO:0007584 49 49 0,000 0,38640855 0,40166439 ! regulation of ligase activity GO:0051340 50 49 0,000 0,38640855 0,40143797 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,38640855 0,40121181 ! RNA transport GO:0050658 50 50 0,000 0,39251662 0,4073244 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,39251662 0,40709518 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,39251662 0,40686621 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,39251662 0,40663751 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,39856477 0,41267127 ! rRNA metabolic process GO:0016072 51 51 0,000 0,39856477 0,41243957 GO:0006364|rRNA processing, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,39856477 0,41220812 ! protein maturation GO:0051604 51 51 0,000 0,39856477 0,41197693 ! RNA localization GO:0006403 52 52 0,000 0,40455358 0,41793287 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,40455358 0,41769874 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,40455358 0,41746486 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,40455358 0,41723125 ! sodium ion transport GO:0006814 53 53 0,000 0,41048363 0,42311036 ! tRNA metabolic process GO:0006399 53 53 0,000 0,41048363 0,42287385 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,41048363 0,42263761 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,41048363 0,42240163 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,41048363 0,42216592 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,41635548 0,42796606 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,42216969 0,43370052 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! microtubule cytoskeleton organization GO:0000226 55 55 0,000 0,42216969 0,43345891 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,42792683 0,43912536 ! regulation of nervous system development GO:0051960 57 56 0,000 0,42792683 0,43888099 ! ATP metabolic process GO:0046034 57 57 0,000 0,43362744 0,44448018 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,43362744 0,44423311 ! innate immune response GO:0045087 58 58 0,000 0,43927207 0,44976579 ! dephosphorylation GO:0016311 60 59 0,000 0,44486127 0,4552356 ! carboxylic acid transport GO:0046942 59 59 0,000 0,44486127 0,45498297 GO:0015849|organic acid transport, ! regulation of cell development GO:0060284 60 59 0,000 0,44486127 0,45473063 ! sterol metabolic process GO:0016125 59 59 0,000 0,44486127 0,45447856 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,44486127 0,45422677 ! potassium ion transport GO:0006813 60 60 0,000 0,45039557 0,45962294 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,45039557 0,45936858 ! cellular respiration GO:0045333 62 61 0,000 0,45587549 0,46470052 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,45587549 0,46444363 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,46130158 0,46971205 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,46130158 0,46945268 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,46130158 0,4691936 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,46130158 0,46893481 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,46667434 0,47413495 ! glucose metabolic process GO:0006006 63 63 0,000 0,46667434 0,47387372 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,46667434 0,47361278 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,46667434 0,47335212 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,4719943 0,47848487 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,4719943 0,47822182 ! anion transport GO:0006820 65 65 0,000 0,47726196 0,48329329 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,48247783 0,48830678 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,48247783 0,48803877 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,48247783 0,48777106 ! muscle contraction GO:0006936 67 67 0,000 0,48764242 0,49272203 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,49275622 0,49761628 ! response to nutrient levels GO:0031667 69 69 0,000 0,49781972 0,50245441 ! translational elongation GO:0006414 71 71 0,000 0,50779778 0,51224483 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,50779778 0,51196461 ! ribosome biogenesis GO:0042254 71 71 0,000 0,50779778 0,5116847 ! muscle system process GO:0003012 72 72 0,000 0,5127133 0,51635552 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,5127133 0,51607352 ! electron transport chain GO:0022900 75 74 0,000 0,52239967 0,52553635 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,52717147 0,53004747 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,52717147 0,52975846 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,55033475 0,55273403 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,56369221 0,56584136 ! ncRNA processing GO:0034470 83 83 0,000 0,56369221 0,56553334 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,57665854 0,57822725 GO:0006644|phospholipid metabolic process, ! hexose metabolic process GO:0019318 87 86 0,000 0,57665854 0,57791282 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,58509105 0,586045 ! visual perception GO:0007601 93 92 0,000 0,60146265 0,60211606 GO:0050953|sensory perception of light stimulus, ! endocytosis GO:0006897 99 98 0,000 0,62483359 0,6251728 GO:0010324|membrane invagination, ! regulation of system process GO:0044057 98 98 0,000 0,62483359 0,62483359