pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6466-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! G1/S transition of mitotic cell cycle GO:0000082 115 46 7,000 2,549E-09 6,132E-06 ! glycine biosynthetic process GO:0006545 7 5 3,000 1,827E-08 2,198E-05 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 6,000 3,144E-07 2,522E-04 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 4,000 6,689E-07 4,023E-04 ! interphase of mitotic cell cycle GO:0051329 209 95 7,000 8,538E-07 4,108E-04 ! negative regulation of protein kinase activity GO:0006469 130 67 6,000 9,678E-07 3,881E-04 ! negative regulation of kinase activity GO:0033673 131 68 6,000 1,072E-06 3,683E-04 ! interphase GO:0051325 213 98 7,000 1,083E-06 3,258E-04 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 3,000 1,162E-06 3,106E-04 ! negative regulation of transferase activity GO:0051348 140 72 6,000 1,586E-06 3,815E-04 ! serine family amino acid biosynthetic process GO:0009070 17 13 3,000 2,486E-06 5,438E-04 ! negative regulation of growth GO:0045926 155 84 6,000 4,502E-06 9,027E-04 ! hemoglobin biosynthetic process GO:0042541 7 5 2,000 4,696E-06 8,692E-04 ! positive regulation of chemokine production GO:0032722 8 5 2,000 4,696E-06 8,071E-04 ! positive regulation of cell migration GO:0030335 126 57 5,000 5,645E-06 9,055E-04 ! gland development GO:0048732 206 88 6,000 6,145E-06 9,241E-04 ! cytokine-mediated signaling pathway GO:0019221 97 59 5,000 6,918E-06 9,792E-04 ! glycine metabolic process GO:0006544 28 17 3,000 8,074E-06 1,079E-03 ! positive regulation of cell motion GO:0051272 146 64 5,000 1,114E-05 1,411E-03 ! cell cycle arrest GO:0007050 213 100 6,000 1,431E-05 1,722E-03 ! negative regulation of cell growth GO:0030308 132 67 5,000 1,454E-05 1,666E-03 ! prostate gland development GO:0030850 13 7 2,000 1,625E-05 1,777E-03 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 1,625E-05 1,7E-03 ! cranial nerve morphogenesis GO:0021602 11 7 2,000 1,625E-05 1,629E-03 ! regulation of T cell differentiation GO:0045580 70 41 4,000 1,686E-05 1,623E-03 ! negative regulation of cell size GO:0045792 134 69 5,000 1,724E-05 1,596E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 4,000 2,138E-05 1,905E-03 ! hemoglobin metabolic process GO:0020027 13 8 2,000 2,584E-05 2,221E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 2,584E-05 2,144E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 2,584E-05 2,073E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 2,000 2,584E-05 2,006E-03 ! positive regulation of protein transport GO:0051222 72 46 4,000 2,987E-05 2,246E-03 ! negative regulation of phosphorylation GO:0042326 47 24 3,000 3,453E-05 2,517E-03 ! regulation of lymphocyte differentiation GO:0045619 81 48 4,000 3,684E-05 2,607E-03 ! regulation of mast cell proliferation GO:0070666 81 48 4,000 3,684E-05 2,533E-03 ! response to hypoxia GO:0001666 171 81 5,000 4,317E-05 2,885E-03 ! regulation of endothelial cell proliferation GO:0001936 57 26 3,000 4,799E-05 3,12E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 3,000 4,799E-05 3,038E-03 GO:0045936|negative regulation of phosphate metabolic process, ! response to oxygen levels GO:0070482 176 83 5,000 4,956E-05 3,058E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 4,000 4,959E-05 2,983E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of angiogenesis GO:0045765 114 52 4,000 5,451E-05 3,199E-03 ! covalent chromatin modification GO:0016569 101 52 4,000 5,451E-05 3,123E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 5,474E-05 3,063E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 2,000 5,474E-05 2,993E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 2,000 5,474E-05 2,927E-03 ! regulation of protein transport GO:0051223 154 87 5,000 6,46E-05 3,379E-03 GO:0070201|regulation of establishment of protein localization, ! regulation of nitric-oxide synthase activity GO:0050999 26 11 2,000 7,483E-05 3,831E-03 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 2,000 7,483E-05 3,751E-03 ! regulation of leukocyte migration GO:0002685 26 11 2,000 7,483E-05 3,674E-03 ! regulation of B cell activation GO:0050864 50 30 3,000 8,583E-05 4,13E-03 ! serine family amino acid metabolic process GO:0009069 49 31 3,000 9,794E-05 4,62E-03 ! regulation of B cell proliferation GO:0030888 20 12 2,000 9,92E-05 4,59E-03 ! cranial nerve development GO:0021545 20 12 2,000 9,92E-05 4,503E-03 ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 9,92E-05 4,42E-03 GO:0042130|negative regulation of T cell proliferation, ! DNA catabolic process GO:0006308 86 59 4,000 1,004E-04 4,394E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 3,000 1,112E-04 4,779E-03 ! regulation of protein localization GO:0032880 176 97 5,000 1,185E-04 5E-03 ! regulation of chemokine production GO:0032642 18 13 2,000 1,282E-04 5,319E-03 ! endocrine pancreas development GO:0031018 22 13 2,000 1,282E-04 5,229E-03 ! regulation of monooxygenase activity GO:0032768 33 13 2,000 1,282E-04 5,141E-03 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 2,000 1,282E-04 5,057E-03 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 2,000 1,622E-04 6,296E-03 ! lung development GO:0030324 144 67 4,000 1,841E-04 7,033E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 4,000 1,841E-04 6,923E-03 ! heterophilic cell adhesion GO:0007157 39 15 2,000 2,016E-04 7,463E-03 ! regulation of T-helper cell differentiation GO:0045622 26 15 2,000 2,016E-04 7,35E-03 ! cell cycle checkpoint GO:0000075 137 69 4,000 2,116E-04 7,598E-03 ! urogenital system development GO:0001655 137 69 4,000 2,116E-04 7,486E-03 ! nucleus organization GO:0006997 67 38 3,000 2,201E-04 7,674E-03 ! respiratory tube development GO:0030323 150 70 4,000 2,264E-04 7,782E-03 ! regulation of neurotransmitter secretion GO:0046928 33 16 2,000 2,467E-04 8,361E-03 ! DNA replication initiation GO:0006270 27 16 2,000 2,467E-04 8,245E-03 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 2,000 2,467E-04 8,132E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 2,467E-04 8,022E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! respiratory system development GO:0060541 153 72 4,000 2,584E-04 8,291E-03 ! multicellular organismal metabolic process GO:0044236 57 40 3,000 2,692E-04 8,521E-03 ! regulation of T cell proliferation GO:0042129 71 41 3,000 2,964E-04 9,263E-03 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 2,979E-04 9,188E-03 ! regulation of intracellular protein transport GO:0033157 80 42 3,000 3,257E-04 9,918E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 3,554E-04 0,01068769 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 3,554E-04 0,01055574 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 2,000 3,554E-04 0,01042701 ! nerve development GO:0021675 28 18 2,000 3,554E-04 0,01030139 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 3,000 3,569E-04 0,01022143 ! JAK-STAT cascade GO:0007259 71 44 3,000 3,901E-04 0,01104345 ! positive regulation of phosphorylation GO:0042327 129 79 4,000 3,982E-04 0,0111414 ! positive regulation of translation GO:0045727 30 19 2,000 4,196E-04 0,01160312 ! pigmentation during development GO:0048066 41 19 2,000 4,196E-04 0,01147126 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 2,000 4,196E-04 0,01134237 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 4,256E-04 0,01137759 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 4,000 4,47E-04 0,0118194 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of nucleocytoplasmic transport GO:0046822 85 46 3,000 4,633E-04 0,01211588 ! pigmentation GO:0043473 100 46 3,000 4,633E-04 0,0119856 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 4,908E-04 0,0125613 ! response to alkaloid GO:0043279 38 20 2,000 4,908E-04 0,01242907 ! pancreas development GO:0031016 35 20 2,000 4,908E-04 0,0122996 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 4,908E-04 0,0121728 ! peptidyl-serine modification GO:0018209 43 20 2,000 4,908E-04 0,01204859 ! negative regulation of T cell activation GO:0050868 40 20 2,000 4,908E-04 0,01192689 ! one-carbon metabolic process GO:0006730 154 85 4,000 5,58E-04 0,01342539 ! regulation of neurotransmitter transport GO:0051588 42 21 2,000 5,692E-04 0,01356051 ! inactivation of MAPK activity GO:0000188 39 21 2,000 5,692E-04 0,01342756 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 5,692E-04 0,0132972 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 2,000 5,692E-04 0,01316934 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 2,000 5,692E-04 0,01304392 ! positive regulation of locomotion GO:0040017 39 21 2,000 5,692E-04 0,01292086 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! endocrine system development GO:0035270 104 49 3,000 5,906E-04 0,0132797 ! positive regulation of helicase activity GO:0051096 11 5 1,000 6,02E-04 0,01341159 ! negative regulation of bone resorption GO:0045779 10 5 1,000 6,02E-04 0,01328855 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 1,000 6,02E-04 0,01316774 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! cell adhesion mediated by integrin GO:0033627 8 5 1,000 6,02E-04 0,01304912 ! regulation of collagen biosynthetic process GO:0032965 6 5 1,000 6,02E-04 0,01293261 ! serotonin receptor signaling pathway GO:0007210 10 5 1,000 6,02E-04 0,01281816 ! response to protozoan GO:0001562 10 5 1,000 6,02E-04 0,01270572 ! positive regulation of glycolysis GO:0045821 14 5 1,000 6,02E-04 0,01259523 ! positive regulation of neurotransmitter secretion GO:0001956 11 5 1,000 6,02E-04 0,01248665 ! epithelial cell proliferation GO:0050673 9 5 1,000 6,02E-04 0,01237993 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 6,02E-04 0,01227502 ! neutrophil mediated immunity GO:0002446 7 5 1,000 6,02E-04 0,01217186 ! microvillus organization GO:0032528 7 5 1,000 6,02E-04 0,01207043 GO:0030033|microvillus assembly, ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 1,000 6,02E-04 0,01197068 ! mRNA transcription GO:0009299 9 5 1,000 6,02E-04 0,01187256 ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 6,02E-04 0,01177603 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 6,02E-04 0,01168106 ! substrate-bound cell migration, cell extension GO:0006930 6 5 1,000 6,02E-04 0,01158762 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 6,02E-04 0,01149565 ! positive regulation of vasoconstriction GO:0045907 9 5 1,000 6,02E-04 0,01140513 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 6,02E-04 0,01131603 ! regulation of sensory perception GO:0051931 7 5 1,000 6,02E-04 0,01122831 GO:0051930|regulation of sensory perception of pain, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 1,000 6,02E-04 0,01114194 GO:0022011|myelination in the peripheral nervous system, ! stem cell division GO:0017145 11 5 1,000 6,02E-04 0,01105688 GO:0048103|somatic stem cell division, ! organ regeneration GO:0031100 7 5 1,000 6,02E-04 0,01097312 ! histone modification GO:0016570 91 50 3,000 6,38E-04 0,01154188 ! regulation of chemotaxis GO:0050920 40 22 2,000 6,553E-04 0,0117666 ! apoptotic nuclear changes GO:0030262 32 22 2,000 6,553E-04 0,01167944 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 6,553E-04 0,01159356 ! positive regulation of B cell activation GO:0050871 38 22 2,000 6,553E-04 0,01150893 ! cellular amino acid biosynthetic process GO:0008652 75 51 3,000 6,881E-04 0,01199682 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 3,000 6,881E-04 0,01191051 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 2,000 7,493E-04 0,01287703 ! positive regulation of MAP kinase activity GO:0043406 160 93 4,000 8,405E-04 0,01434188 ! positive regulation of fibroblast proliferation GO:0048146 43 24 2,000 8,514E-04 0,01442575 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 8,514E-04 0,01432487 ! regulation of behavior GO:0050795 43 24 2,000 8,514E-04 0,01422539 ! regulation of alpha-beta T cell activation GO:0046634 42 24 2,000 8,514E-04 0,01412729 ! lymphocyte proliferation GO:0046651 48 24 2,000 8,514E-04 0,01403052 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 8,514E-04 0,01393508 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 3,000 8,55E-04 0,01389911 ! regulation of T cell activation GO:0050863 158 94 4,000 8,821E-04 0,01424402 ! regulation of hormone biosynthetic process GO:0046885 10 6 1,000 8,984E-04 0,01440963 ! forebrain regionalization GO:0021871 8 6 1,000 8,984E-04 0,0143142 ! male meiosis GO:0007140 7 6 1,000 8,984E-04 0,01422003 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 1,000 8,984E-04 0,01412709 ! erythrocyte maturation GO:0043249 7 6 1,000 8,984E-04 0,01403535 ! embryonic hemopoiesis GO:0035162 14 6 1,000 8,984E-04 0,0139448 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 1,000 8,984E-04 0,01385541 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 1,000 8,984E-04 0,01376716 GO:0033135|regulation of peptidyl-serine phosphorylation, ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 8,984E-04 0,01368003 ! T cell mediated immunity GO:0002456 16 6 1,000 8,984E-04 0,01359399 ! regulation of immunoglobulin secretion GO:0051023 6 6 1,000 8,984E-04 0,01350903 ! regulation of collagen metabolic process GO:0010712 9 6 1,000 8,984E-04 0,01342512 ! neural nucleus development GO:0048857 14 6 1,000 8,984E-04 0,01334225 ! astrocyte development GO:0014002 15 6 1,000 8,984E-04 0,01326039 ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 8,984E-04 0,01317954 ! Schwann cell development GO:0014044 15 6 1,000 8,984E-04 0,01309966 ! neutrophil homeostasis GO:0001780 10 6 1,000 8,984E-04 0,01302075 ! salivary gland morphogenesis GO:0007435 13 6 1,000 8,984E-04 0,01294278 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 1,000 8,984E-04 0,01286574 GO:0045625|regulation of T-helper 1 cell differentiation, ! ectodermal gut morphogenesis GO:0048567 12 6 1,000 8,984E-04 0,01278961 GO:0007439|ectodermal gut development, ! organ or tissue specific immune response GO:0002251 7 6 1,000 8,984E-04 0,01271438 ! negative regulation of B cell activation GO:0050869 13 6 1,000 8,984E-04 0,01264002 ! myelination GO:0042552 45 25 2,000 9,619E-04 0,01345574 ! positive regulation of protein secretion GO:0050714 36 25 2,000 9,619E-04 0,01337797 ! regulation of DNA metabolic process GO:0051052 178 97 4,000 1,016E-03 0,0140519 ! regulation of intracellular transport GO:0032386 101 57 3,000 1,049E-03 0,01441553 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 1,081E-03 0,01477958 ! leukocyte proliferation GO:0070661 52 26 2,000 1,081E-03 0,01469608 GO:0032943|mononuclear cell proliferation, ! positive regulation of secretion GO:0051047 95 59 3,000 1,193E-03 0,01613138 ! skeletal system morphogenesis GO:0048705 105 59 3,000 1,193E-03 0,01604126 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 1,209E-03 0,01616399 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 2,000 1,209E-03 0,01607469 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 1,209E-03 0,01598637 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 1,209E-03 0,01589901 ! regulation of helicase activity GO:0051095 15 7 1,000 1,251E-03 0,01636079 ! regulation of lipid kinase activity GO:0043550 13 7 1,000 1,251E-03 0,01627236 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,251E-03 0,01618487 ! mRNA stabilization GO:0048255 18 7 1,000 1,251E-03 0,01609832 GO:0043489|RNA stabilization, ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 1,251E-03 0,01601269 ! positive regulation of neurotransmitter transport GO:0051590 16 7 1,000 1,251E-03 0,01592797 ! regulation of dopamine metabolic process GO:0042053 11 7 1,000 1,251E-03 0,01584414 GO:0042069|regulation of catecholamine metabolic process, ! spinal cord patterning GO:0021511 13 7 1,000 1,251E-03 0,01576118 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 1,000 1,251E-03 0,01567909 ! maintenance of protein location in nucleus GO:0051457 19 7 1,000 1,251E-03 0,01559785 ! negative regulation of DNA recombination GO:0045910 15 7 1,000 1,251E-03 0,01551745 ! wound healing, spreading of epidermal cells GO:0035313 14 7 1,000 1,251E-03 0,01543788 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 1,251E-03 0,01535911 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 1,251E-03 0,01528115 ! oxygen homeostasis GO:0032364 12 7 1,000 1,251E-03 0,01520397 ! peptidyl-threonine modification GO:0018210 25 7 1,000 1,251E-03 0,01512757 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 1,000 1,251E-03 0,01505193 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 1,000 1,251E-03 0,01497704 ! defense response to Gram-negative bacterium GO:0050829 9 7 1,000 1,251E-03 0,0149029 ! positive regulation of T cell differentiation GO:0045582 42 28 2,000 1,347E-03 0,01596019 ! regulation of homeostatic process GO:0032844 134 62 3,000 1,436E-03 0,01693938 ! cellular iron ion homeostasis GO:0006879 51 29 2,000 1,493E-03 0,01752673 ! cell junction assembly GO:0034329 78 30 2,000 1,65E-03 0,01926823 ! ensheathment of neurons GO:0007272 57 30 2,000 1,65E-03 0,01917514 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 1,65E-03 0,01908295 ! neurotransmitter secretion GO:0007269 48 30 2,000 1,65E-03 0,01899165 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,66E-03 0,01901486 ! regulation of cellular amine metabolic process GO:0033238 12 8 1,000 1,66E-03 0,01892474 ! macrophage chemotaxis GO:0048246 12 8 1,000 1,66E-03 0,01883548 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,66E-03 0,01874705 ! T-helper 1 type immune response GO:0042088 12 8 1,000 1,66E-03 0,01865944 ! inositol phosphate-mediated signaling GO:0048016 11 8 1,000 1,66E-03 0,01857266 ! astrocyte differentiation GO:0048708 18 8 1,000 1,66E-03 0,01848667 ! ER overload response GO:0006983 12 8 1,000 1,66E-03 0,01840148 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 1,66E-03 0,01831707 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 1,66E-03 0,01823343 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,66E-03 0,01815055 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 1,000 1,66E-03 0,01806842 ! Schwann cell differentiation GO:0014037 19 8 1,000 1,66E-03 0,01798703 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 1,66E-03 0,01790637 ! regulation of T-helper 1 type immune response GO:0002825 9 8 1,000 1,66E-03 0,01782643 ! myeloid cell homeostasis GO:0002262 13 8 1,000 1,66E-03 0,0177472 ! behavioral response to nicotine GO:0035095 12 8 1,000 1,66E-03 0,01766868 ! collagen metabolic process GO:0032963 45 31 2,000 1,816E-03 0,01924795 ! iron ion homeostasis GO:0055072 54 31 2,000 1,816E-03 0,01916353 ! erythrocyte differentiation GO:0030218 55 31 2,000 1,816E-03 0,01907985 ! homeostasis of number of cells GO:0048872 114 67 3,000 1,914E-03 0,02002431 ! peripheral nervous system development GO:0007422 64 32 2,000 1,992E-03 0,02075148 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 2,000 1,992E-03 0,02066204 ! positive regulation of catabolic process GO:0009896 64 32 2,000 1,992E-03 0,02057336 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 2,123E-03 0,021827 ! cell proliferation in forebrain GO:0021846 15 9 1,000 2,123E-03 0,02173412 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 1,000 2,123E-03 0,02164203 GO:0010469|regulation of receptor activity, ! induction of positive chemotaxis GO:0050930 15 9 1,000 2,123E-03 0,02155071 ! regulation of glycolysis GO:0006110 21 9 1,000 2,123E-03 0,02146016 ! cerebral cortex cell migration GO:0021795 15 9 1,000 2,123E-03 0,02137037 ! microtubule bundle formation GO:0001578 21 9 1,000 2,123E-03 0,02128132 ! middle ear morphogenesis GO:0042474 14 9 1,000 2,123E-03 0,02119302 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 2,123E-03 0,02110545 ! motor axon guidance GO:0008045 16 9 1,000 2,123E-03 0,02101859 ! erythrocyte development GO:0048821 15 9 1,000 2,123E-03 0,02093245 ! gas homeostasis GO:0033483 16 9 1,000 2,123E-03 0,02084701 ! spinal cord motor neuron differentiation GO:0021522 15 9 1,000 2,123E-03 0,02076227 ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 2,123E-03 0,02067821 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 2,123E-03 0,02059483 ! regulation of telomere maintenance GO:0032204 14 9 1,000 2,123E-03 0,02051212 ! regulation of amino acid transport GO:0051955 11 9 1,000 2,123E-03 0,02043007 ! positive regulation of gene-specific transcription GO:0043193 65 33 2,000 2,179E-03 0,02088718 ! leukocyte chemotaxis GO:0030595 50 33 2,000 2,179E-03 0,02080429 GO:0060326|cell chemotaxis, ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 2,000 2,376E-03 0,022597 ! glial cell differentiation GO:0010001 63 34 2,000 2,376E-03 0,02250804 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 2,000 2,376E-03 0,02241977 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 3,000 2,492E-03 0,02342388 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 2,000 2,584E-03 0,02419123 ! embryonic skeletal system morphogenesis GO:0048704 59 35 2,000 2,584E-03 0,02409746 ! telencephalon development GO:0021537 68 35 2,000 2,584E-03 0,02400442 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 1,000 2,64E-03 0,02442873 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 2,64E-03 0,02433514 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 2,64E-03 0,02424225 ! smoothened signaling pathway GO:0007224 16 10 1,000 2,64E-03 0,02415008 ! lung alveolus development GO:0048286 26 10 1,000 2,64E-03 0,0240586 ! regulation of chemokine biosynthetic process GO:0045073 12 10 1,000 2,64E-03 0,02396781 ! negative regulation of striated muscle development GO:0045843 19 10 1,000 2,64E-03 0,02387771 ! myeloid leukocyte mediated immunity GO:0002444 14 10 1,000 2,64E-03 0,02378828 ! epithelial cell development GO:0002064 20 10 1,000 2,64E-03 0,02369952 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 1,000 2,64E-03 0,02361142 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 2,64E-03 0,02352397 ! regulation of bone resorption GO:0045124 25 10 1,000 2,64E-03 0,02343716 ! positive regulation of interleukin-6 production GO:0032755 14 10 1,000 2,64E-03 0,023351 ! salivary gland development GO:0007431 27 10 1,000 2,64E-03 0,02326546 ! positive regulation of acute inflammatory response GO:0002675 16 10 1,000 2,64E-03 0,02318055 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 2,64E-03 0,02309626 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 1,000 2,64E-03 0,02301258 ! positive regulation of amine transport GO:0051954 16 10 1,000 2,64E-03 0,0229295 ! response to nicotine GO:0035094 20 10 1,000 2,64E-03 0,02284702 ! localization within membrane GO:0051668 20 10 1,000 2,64E-03 0,02276513 ! regulation of transcription factor activity GO:0051090 126 74 3,000 2,754E-03 0,02366291 GO:0090046|regulation of transcription regulator activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 2,000 2,803E-03 0,02399805 ! cell junction organization GO:0034330 86 36 2,000 2,803E-03 0,02391295 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 2,803E-03 0,02382845 ! embryonic organ development GO:0048568 57 36 2,000 2,803E-03 0,02374455 ! negative regulation of cell activation GO:0050866 65 36 2,000 2,803E-03 0,02366123 ! tissue remodeling GO:0048771 76 37 2,000 3,033E-03 0,02551188 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 3,033E-03 0,02542299 ! positive regulation of lymphocyte activation GO:0051251 127 77 3,000 3,18E-03 0,02656872 ! negative regulation of muscle development GO:0048635 20 11 1,000 3,21E-03 0,02672283 ! neuron fate specification GO:0048665 17 11 1,000 3,21E-03 0,02663068 ! telencephalon cell migration GO:0022029 20 11 1,000 3,21E-03 0,02653917 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 1,000 3,21E-03 0,02644828 GO:0046579|positive regulation of Ras protein signal transduction, ! detection of mechanical stimulus GO:0050982 22 11 1,000 3,21E-03 0,02635801 ! T cell proliferation GO:0042098 26 11 1,000 3,21E-03 0,02626836 ! blood vessel remodeling GO:0001974 29 11 1,000 3,21E-03 0,02617932 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 3,21E-03 0,02609087 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 3,21E-03 0,02600302 ! ventral spinal cord development GO:0021517 21 11 1,000 3,21E-03 0,02591577 ! melanocyte differentiation GO:0030318 21 11 1,000 3,21E-03 0,02582909 GO:0050931|pigment cell differentiation, ! substrate-bound cell migration GO:0006929 13 11 1,000 3,21E-03 0,02574299 ! adult heart development GO:0007512 14 11 1,000 3,21E-03 0,02565747 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 1,000 3,21E-03 0,02557251 ! embryonic gut development GO:0048566 15 11 1,000 3,21E-03 0,02548811 ! regulation of organic acid transport GO:0032890 18 11 1,000 3,21E-03 0,02540427 ! defense response to Gram-positive bacterium GO:0050830 13 11 1,000 3,21E-03 0,02532098 ! carbohydrate homeostasis GO:0033500 53 38 2,000 3,274E-03 0,02573992 GO:0042593|glucose homeostasis, ! erythrocyte homeostasis GO:0034101 64 38 2,000 3,274E-03 0,02565608 ! positive regulation of leukocyte proliferation GO:0070665 62 38 2,000 3,274E-03 0,02557278 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 2,000 3,526E-03 0,02745603 ! regulation of action potential in neuron GO:0019228 73 39 2,000 3,526E-03 0,02736746 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 2,000 3,79E-03 0,02932247 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 3,832E-03 0,02955046 ! regulation of positive chemotaxis GO:0050926 19 12 1,000 3,832E-03 0,02945605 GO:0050927|positive regulation of positive chemotaxis, ! oligodendrocyte differentiation GO:0048709 16 12 1,000 3,832E-03 0,02936224 ! focal adhesion formation GO:0048041 35 12 1,000 3,832E-03 0,02926902 ! forebrain cell migration GO:0021885 21 12 1,000 3,832E-03 0,0291764 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 1,000 3,832E-03 0,02908436 GO:0002717|positive regulation of natural killer cell mediated immunity, ! histone acetylation GO:0016573 26 12 1,000 3,832E-03 0,0289929 ! histone methylation GO:0016571 26 12 1,000 3,832E-03 0,02890201 ! autonomic nervous system development GO:0048483 24 12 1,000 3,832E-03 0,0288117 ! gland morphogenesis GO:0022612 29 12 1,000 3,832E-03 0,02872194 ! regulation of hormone metabolic process GO:0032350 26 12 1,000 3,832E-03 0,02863274 ! peptidyl-lysine modification GO:0018205 21 12 1,000 3,832E-03 0,02854409 ! digestive tract morphogenesis GO:0048546 26 12 1,000 3,832E-03 0,028456 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! leukocyte mediated cytotoxicity GO:0001909 26 12 1,000 3,832E-03 0,02836844 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 3,832E-03 0,02828142 ! gliogenesis GO:0042063 88 41 2,000 4,066E-03 0,02991719 ! dorsal/ventral pattern formation GO:0009953 68 41 2,000 4,066E-03 0,02982598 ! positive regulation of transcription factor activity GO:0051091 62 42 2,000 4,354E-03 0,03183947 GO:0090047|positive regulation of transcription regulator activity, ! regulation of protein secretion GO:0050708 71 42 2,000 4,354E-03 0,03174298 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 4,354E-03 0,03164708 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 1,000 4,505E-03 0,03265052 ! exocrine system development GO:0035272 32 13 1,000 4,505E-03 0,03255247 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 4,505E-03 0,032455 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of natural killer cell mediated immunity GO:0002715 27 13 1,000 4,505E-03 0,03235812 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! chromatin silencing GO:0006342 26 13 1,000 4,505E-03 0,03226182 ! regulation of acute inflammatory response GO:0002673 21 13 1,000 4,505E-03 0,03216609 ! regulation of mRNA stability GO:0043488 31 13 1,000 4,505E-03 0,03207092 ! embryonic placenta development GO:0001892 23 13 1,000 4,505E-03 0,03197632 ! positive regulation of cell activation GO:0050867 145 85 3,000 4,533E-03 0,03207755 GO:0002696|positive regulation of leukocyte activation, ! positive regulation of response to external stimulus GO:0032103 77 43 2,000 4,654E-03 0,0328341 ! neural tube development GO:0021915 77 43 2,000 4,654E-03 0,03273809 ! amine biosynthetic process GO:0009309 138 86 3,000 4,725E-03 0,03314662 ! tube morphogenesis GO:0035239 176 86 3,000 4,725E-03 0,03305027 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 2,000 4,966E-03 0,03462897 ! positive regulation of protein modification process GO:0031401 136 88 3,000 5,127E-03 0,03564851 ! regulation of DNA binding GO:0051101 155 88 3,000 5,127E-03 0,03554577 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 5,229E-03 0,03615395 ! hair follicle morphogenesis GO:0031069 26 14 1,000 5,229E-03 0,03605036 ! regulation of mRNA processing GO:0050684 24 14 1,000 5,229E-03 0,03594736 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 1,000 5,229E-03 0,03584495 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 1,000 5,229E-03 0,03574311 ! regulation of T-helper 2 type immune response GO:0002828 24 14 1,000 5,229E-03 0,03564186 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 5,229E-03 0,03554117 ! regulation of RNA stability GO:0043487 32 14 1,000 5,229E-03 0,03544106 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 5,229E-03 0,03534151 ! regulation of JAK-STAT cascade GO:0046425 70 45 2,000 5,29E-03 0,03565045 ! leukocyte migration GO:0050900 68 45 2,000 5,29E-03 0,03555086 ! branching morphogenesis of a tube GO:0048754 97 45 2,000 5,29E-03 0,03545184 ! cell growth GO:0016049 84 45 2,000 5,29E-03 0,03535336 ! regulation of cell morphogenesis GO:0022604 215 89 3,000 5,335E-03 0,03555921 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 5,627E-03 0,0373961 ! response to insulin stimulus GO:0032868 95 46 2,000 5,627E-03 0,03729308 ! positive regulation of defense response GO:0031349 76 47 2,000 5,976E-03 0,03949953 ! response to calcium ion GO:0051592 81 47 2,000 5,976E-03 0,03939131 ! positive regulation of DNA binding GO:0043388 73 47 2,000 5,976E-03 0,03928368 ! regulation of adaptive immune response GO:0002819 84 47 2,000 5,976E-03 0,03917664 ! positive regulation of cell size GO:0045793 27 15 1,000 6,003E-03 0,03924612 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 6,003E-03 0,03913976 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 1,000 6,003E-03 0,03903397 ! pituitary gland development GO:0021983 29 15 1,000 6,003E-03 0,03892876 ! regulation of exocytosis GO:0017157 22 15 1,000 6,003E-03 0,03882411 ! G1/S transition checkpoint GO:0031575 40 15 1,000 6,003E-03 0,03872003 ! histone deacetylation GO:0016575 20 15 1,000 6,003E-03 0,0386165 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 6,003E-03 0,03851352 ! muscle maintenance GO:0046716 26 15 1,000 6,003E-03 0,03841109 ! dopamine metabolic process GO:0042417 35 15 1,000 6,003E-03 0,03830921 ! cell killing GO:0001906 29 15 1,000 6,003E-03 0,03820786 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 6,003E-03 0,03810705 ! positive regulation of cell cycle GO:0045787 89 48 2,000 6,338E-03 0,04012847 ! cellular component disassembly GO:0022411 86 48 2,000 6,338E-03 0,04002315 ! activation of caspase activity GO:0006919 84 48 2,000 6,338E-03 0,03991838 ! transcription initiation GO:0006352 153 94 3,000 6,465E-03 0,04061392 ! regulation of action potential GO:0001508 95 49 2,000 6,713E-03 0,04205896 ! DNA-dependent DNA replication GO:0006261 74 49 2,000 6,713E-03 0,04194971 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 6,825E-03 0,04254143 ! embryonic forelimb morphogenesis GO:0035115 28 16 1,000 6,825E-03 0,04243151 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 6,825E-03 0,04232215 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 1,000 6,825E-03 0,04221335 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 1,000 6,825E-03 0,04210511 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 6,825E-03 0,04199742 GO:0031114|regulation of microtubule depolymerization, ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 6,825E-03 0,04189029 ! positive regulation of cytokine secretion GO:0050715 26 16 1,000 6,825E-03 0,0417837 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 6,825E-03 0,04167765 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 1,000 6,825E-03 0,04157213 ! defense response to virus GO:0051607 37 16 1,000 6,825E-03 0,04146715 ! detection of stimulus GO:0051606 151 96 3,000 6,958E-03 0,04216962 ! negative regulation of immune system process GO:0002683 95 50 2,000 7,1E-03 0,04292349 ! positive regulation of cytokine production GO:0001819 86 50 2,000 7,1E-03 0,04281591 ! response to virus GO:0009615 160 98 3,000 7,475E-03 0,04496463 ! positive regulation of binding GO:0051099 78 51 2,000 7,501E-03 0,04500698 ! viral infectious cycle GO:0019058 99 51 2,000 7,501E-03 0,04489502 ! embryonic skeletal system development GO:0048706 85 51 2,000 7,501E-03 0,04478362 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 2,000 7,501E-03 0,04467277 ! chromatin remodeling GO:0006338 109 51 2,000 7,501E-03 0,04456246 ! regulation of cell shape GO:0008360 125 51 2,000 7,501E-03 0,0444527 ! epithelial tube morphogenesis GO:0060562 98 51 2,000 7,501E-03 0,04434348 ! positive regulation of cell killing GO:0031343 32 17 1,000 7,695E-03 0,04537967 ! negative regulation of hormone secretion GO:0046888 25 17 1,000 7,695E-03 0,04526872 ! glial cell development GO:0021782 27 17 1,000 7,695E-03 0,04515831 ! limbic system development GO:0021761 36 17 1,000 7,695E-03 0,04504843 ! heart looping GO:0001947 30 17 1,000 7,695E-03 0,04493909 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 1,000 7,695E-03 0,04483028 ! cell differentiation in spinal cord GO:0021515 30 17 1,000 7,695E-03 0,04472199 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 7,695E-03 0,04461423 ! regulation of survival gene product expression GO:0045884 33 17 1,000 7,695E-03 0,04450698 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 7,695E-03 0,04440025 ! DNA unwinding during replication GO:0006268 27 17 1,000 7,695E-03 0,04429403 ! neural crest cell migration GO:0001755 37 17 1,000 7,695E-03 0,04418832 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 7,695E-03 0,04408311 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 7,695E-03 0,0439784 ! morphogenesis of a branching structure GO:0001763 111 52 2,000 7,915E-03 0,04512708 ! cell maturation GO:0048469 100 53 2,000 8,342E-03 0,04744979 ! response to UV GO:0009411 104 53 2,000 8,342E-03 0,04733788 ! positive regulation of anti-apoptosis GO:0045768 39 18 1,000 8,613E-03 0,04875857 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 8,613E-03 0,04864411 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 1,000 8,613E-03 0,04853019 ! memory GO:0007613 31 18 1,000 8,613E-03 0,0484168 ! epidermis morphogenesis GO:0048730 40 18 1,000 8,613E-03 0,04830394 ! regulation of immunoglobulin production GO:0002637 43 18 1,000 8,613E-03 0,04819161 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 8,613E-03 0,0480798 ! activation of phospholipase C activity GO:0007202 103 54 2,000 8,783E-03 0,04891417 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of caspase activity GO:0043280 95 55 2,000 9,236E-03 0,05132288 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 2,000 9,236E-03 0,05120462 ! RNA elongation GO:0006354 79 55 2,000 9,236E-03 0,05108691 ! positive regulation of angiogenesis GO:0045766 44 19 1,000 9,577E-03 0,05284761 ! lipid phosphorylation GO:0046834 35 19 1,000 9,577E-03 0,05272668 ! forelimb morphogenesis GO:0035136 32 19 1,000 9,577E-03 0,0526063 ! cerebral cortex development GO:0021987 36 19 1,000 9,577E-03 0,05248647 ! actin filament bundle formation GO:0051017 42 19 1,000 9,577E-03 0,05236718 ! neuromuscular junction development GO:0007528 34 19 1,000 9,577E-03 0,05224843 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 9,577E-03 0,05213022 ! G1 phase GO:0051318 40 19 1,000 9,577E-03 0,05201255 ! proximal/distal pattern formation GO:0009954 32 19 1,000 9,577E-03 0,0518954 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 1,000 9,577E-03 0,05177878 ! embryonic organ morphogenesis GO:0048562 26 19 1,000 9,577E-03 0,05166269 ! peptide hormone secretion GO:0030072 31 19 1,000 9,577E-03 0,05154711 ! nucleotide-excision repair GO:0006289 83 56 2,000 9,704E-03 0,05211409 ! regulation of bone remodeling GO:0046850 137 57 2,000 0,01018455 0,05457466 ! lipid modification GO:0030258 97 57 2,000 0,01018455 0,05445339 ! regulation of phospholipase activity GO:0010517 106 57 2,000 0,01018455 0,05433265 ! protein amino acid deacetylation GO:0006476 29 20 1,000 0,01058626 0,05635074 ! protein amino acid acetylation GO:0006473 39 20 1,000 0,01058626 0,05622635 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 0,01058626 0,0561025 GO:0010675|regulation of cellular carbohydrate metabolic process, ! DNA duplex unwinding GO:0032508 31 20 1,000 0,01058626 0,0559792 GO:0032392|DNA geometric change, ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 0,01058626 0,05585644 ! peptide secretion GO:0002790 35 20 1,000 0,01058626 0,05573422 ! regulation of interleukin-2 production GO:0032663 35 20 1,000 0,01058626 0,05561253 ! diencephalon development GO:0021536 34 20 1,000 0,01058626 0,05549136 ! negative regulation of angiogenesis GO:0016525 45 20 1,000 0,01058626 0,05537073 ! detection of chemical stimulus GO:0009593 37 20 1,000 0,01058626 0,05525062 ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 1,000 0,01058626 0,05513103 ! camera-type eye morphogenesis GO:0048593 42 20 1,000 0,01058626 0,05501196 ! regulation of tissue remodeling GO:0034103 140 58 2,000 0,01067902 0,05537438 ! positive regulation of lipase activity GO:0060193 108 58 2,000 0,01067902 0,05525529 ! regulation of cell killing GO:0031341 42 21 1,000 0,01164068 0,06010188 ! hormone secretion GO:0046879 38 21 1,000 0,01164068 0,05997318 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 1,000 0,01164068 0,05984503 ! hindlimb morphogenesis GO:0035137 43 21 1,000 0,01164068 0,05971743 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 0,01164068 0,05959037 ! regulation of vasoconstriction GO:0019229 39 21 1,000 0,01164068 0,05946386 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 0,01164068 0,05933787 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 0,01164068 0,05921242 ! positive regulation of inflammatory response GO:0050729 35 21 1,000 0,01164068 0,0590875 ! positive regulation of osteoblast differentiation GO:0045669 49 21 1,000 0,01164068 0,05896311 ! response to cytokine stimulus GO:0034097 63 21 1,000 0,01164068 0,05883924 ! collagen catabolic process GO:0030574 28 21 1,000 0,01164068 0,05871588 ! gut development GO:0048565 39 21 1,000 0,01164068 0,05859305 ! regulation of neurotransmitter levels GO:0001505 97 60 2,000 0,01170908 0,0588143 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 0,01170908 0,05869177 ! kidney development GO:0001822 122 60 2,000 0,01170908 0,05856975 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 0,0122448 0,06112239 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 0,01273921 0,0634587 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 1,000 0,01273921 0,06332759 ! regeneration GO:0031099 41 22 1,000 0,01273921 0,06319701 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 0,01273921 0,06306698 ! ureteric bud development GO:0001657 43 22 1,000 0,01273921 0,06293748 ! response to glucocorticoid stimulus GO:0051384 38 22 1,000 0,01273921 0,06280851 ! regulation of cytokine secretion GO:0050707 37 22 1,000 0,01273921 0,06268006 ! somatic diversification of immunoglobulins GO:0016445 50 22 1,000 0,01273921 0,06255215 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 0,01273921 0,06242475 ! viral reproductive process GO:0022415 126 62 2,000 0,01279439 0,06256768 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 0,01335789 0,06519085 ! positive regulation of DNA replication GO:0045740 43 23 1,000 0,01388111 0,0676072 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 1,000 0,01388111 0,06747062 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 0,01388111 0,06733459 ! regulation of anti-apoptosis GO:0045767 53 23 1,000 0,01388111 0,06719911 ! viral genome replication GO:0019079 41 23 1,000 0,01388111 0,06706417 ! leukocyte adhesion GO:0007159 50 23 1,000 0,01388111 0,06692977 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 0,01388111 0,06679592 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 1,000 0,01388111 0,06666259 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 0,01388111 0,0665298 ! regulation of interleukin-6 production GO:0032675 29 23 1,000 0,01388111 0,06639753 ! platelet activation GO:0030168 37 23 1,000 0,01388111 0,06626579 ! hormone transport GO:0009914 40 23 1,000 0,01388111 0,06613457 ! response to molecule of bacterial origin GO:0002237 34 23 1,000 0,01388111 0,06600387 ! regulation of cytokine biosynthetic process GO:0042035 95 65 2,000 0,01452683 0,068938 ! embryonic limb morphogenesis GO:0030326 125 65 2,000 0,01452683 0,06880229 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 2,000 0,01452683 0,06866712 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 0,01506563 0,07107434 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 1,000 0,01506563 0,07093525 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 1,000 0,01506563 0,0707967 ! regulation of transmembrane transport GO:0034762 38 24 1,000 0,01506563 0,0706587 ! spinal cord development GO:0021510 47 24 1,000 0,01506563 0,07052123 ! response to corticosteroid stimulus GO:0031960 41 24 1,000 0,01506563 0,0703843 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 1,000 0,01506563 0,07024789 GO:0002708|positive regulation of lymphocyte mediated immunity, ! pallium development GO:0021543 49 24 1,000 0,01506563 0,07011202 ! leukocyte homeostasis GO:0001776 44 24 1,000 0,01506563 0,06997666 ! regulation of amine transport GO:0051952 40 24 1,000 0,01506563 0,06984183 ! developmental maturation GO:0021700 116 66 2,000 0,01513235 0,07001624 ! cell projection assembly GO:0030031 120 66 2,000 0,01513235 0,06988185 ! positive regulation of T cell activation GO:0050870 109 67 2,000 0,01575195 0,07260384 ! adaptive immune response GO:0002250 119 67 2,000 0,01575195 0,07246501 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 1,000 0,01629204 0,07480659 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 0,01629204 0,0746641 ! protein amino acid alkylation GO:0008213 53 25 1,000 0,01629204 0,07452215 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 1,000 0,01629204 0,07438075 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 0,01629204 0,07423987 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 0,01629204 0,07409953 ! neural crest cell development GO:0014032 54 25 1,000 0,01629204 0,07395972 GO:0014033|neural crest cell differentiation, ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 1,000 0,01629204 0,07382044 ! somitogenesis GO:0001756 43 25 1,000 0,01629204 0,07368168 ! immunoglobulin production GO:0002377 55 25 1,000 0,01629204 0,07354344 GO:0002440|production of molecular mediator of immune response, ! neural tube closure GO:0001843 49 25 1,000 0,01629204 0,07340572 GO:0060606|tube closure, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 2,000 0,01638567 0,07368956 ! viral reproduction GO:0016032 134 68 2,000 0,01638567 0,07355208 ! regulation of lipase activity GO:0060191 130 68 2,000 0,01638567 0,07341511 ! initiation of viral infection GO:0019059 57 26 1,000 0,01755962 0,0785287 ! molting cycle process GO:0022404 50 26 1,000 0,01755962 0,07838301 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 1,000 0,01755962 0,07823785 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 0,01755962 0,07809324 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 0,01755962 0,07794915 ! cellular response to oxidative stress GO:0034599 39 26 1,000 0,01755962 0,0778056 ! positive regulation of MAPKKK cascade GO:0043410 47 26 1,000 0,01755962 0,07766257 ! positive regulation of nuclear division GO:0051785 40 26 1,000 0,01755962 0,07752007 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 65 26 1,000 0,01755962 0,0773781 ! somatic diversification of immune receptors GO:0002200 56 26 1,000 0,01755962 0,07723664 ! appendage morphogenesis GO:0035107 135 70 2,000 0,01769554 0,07769246 GO:0035108|limb morphogenesis, ! reproductive structure development GO:0048608 113 71 2,000 0,01837175 0,08051443 ! appendage development GO:0048736 136 71 2,000 0,01837175 0,08036804 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 2,000 0,01837175 0,08022218 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 0,01837175 0,08007685 ! regulation of immune effector process GO:0002697 137 71 2,000 0,01837175 0,07993205 ! neuron fate commitment GO:0048663 48 27 1,000 0,01886765 0,08194143 ! protein amino acid acylation GO:0043543 55 27 1,000 0,01886765 0,08179379 ! positive regulation of innate immune response GO:0045089 43 27 1,000 0,01886765 0,08164668 ! multicellular organismal catabolic process GO:0044243 36 27 1,000 0,01886765 0,0815001 ! primary neural tube formation GO:0014020 51 27 1,000 0,01886765 0,08135404 ! regulation of chromosome organization GO:0033044 42 27 1,000 0,01886765 0,08120851 ! glutathione metabolic process GO:0006749 39 27 1,000 0,01886765 0,08106349 ! regulation of caspase activity GO:0043281 122 72 2,000 0,01906216 0,0817532 ! circadian rhythm GO:0007623 50 28 1,000 0,02021542 0,08654501 ! dendrite development GO:0016358 59 28 1,000 0,02021542 0,08639129 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 0,02021542 0,08623811 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 0,02021542 0,08608548 ! lipid oxidation GO:0034440 43 28 1,000 0,02021542 0,08593338 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 58 28 1,000 0,02021542 0,08578183 ! neurotransmitter transport GO:0006836 123 74 2,000 0,02048564 0,08677546 ! leukocyte mediated immunity GO:0002443 128 74 2,000 0,02048564 0,08662295 ! regulation of endopeptidase activity GO:0052548 125 74 2,000 0,02048564 0,08647098 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 2,000 0,02121874 0,08940857 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 0,02121874 0,08925226 ! catechol metabolic process GO:0009712 54 29 1,000 0,02160224 0,09070678 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! respiratory gaseous exchange GO:0007585 57 29 1,000 0,02160224 0,09054876 ! regulation of production of molecular mediator of immune response GO:0002700 61 29 1,000 0,02160224 0,09039128 ! response to organic cyclic substance GO:0014070 55 29 1,000 0,02160224 0,09023435 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 0,02160224 0,09007797 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 0,02160224 0,08992212 ! tissue homeostasis GO:0001894 48 29 1,000 0,02160224 0,08976681 GO:0048871|multicellular organismal homeostasis, ! cytosolic calcium ion homeostasis GO:0051480 135 76 2,000 0,02196608 0,09112137 ! defense response to bacterium GO:0042742 89 76 2,000 0,02196608 0,09096453 ! regulation of catabolic process GO:0009894 161 76 2,000 0,02196608 0,09080824 ! phenol metabolic process GO:0018958 55 30 1,000 0,02302742 0,09503253 ! regulation of innate immune response GO:0045088 51 30 1,000 0,02302742 0,09486981 ! acute-phase response GO:0006953 49 30 1,000 0,02302742 0,09470764 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,02302742 0,09454602 ! eye morphogenesis GO:0048592 60 30 1,000 0,02302742 0,09438495 ! response to heat GO:0009408 50 30 1,000 0,02302742 0,09422443 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 2,000 0,0235035 0,0960092 ! regulation of peptidase activity GO:0052547 134 79 2,000 0,02429357 0,09906835 ! regulation of synaptic transmission GO:0050804 134 79 2,000 0,02429357 0,09890072 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 1,000 0,02449027 0,09953311 ! positive regulation of T cell proliferation GO:0042102 52 31 1,000 0,02449027 0,09936526 ! peptide transport GO:0015833 55 31 1,000 0,02449027 0,09919798 ! fatty acid catabolic process GO:0009062 48 31 1,000 0,02449027 0,09903126 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 0,02449027 0,0988651 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 1,000 0,02449027 0,0986995 ! response to metal ion GO:0010038 140 80 2,000 0,02509787 0,10097907 ! T cell activation GO:0042110 168 81 2,000 0,0259164 0,10409827 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 1,000 0,02599014 0,10422045 ! metanephros development GO:0001656 74 32 1,000 0,02599014 0,10404703 ! response to ionizing radiation GO:0010212 65 32 1,000 0,02599014 0,1038742 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,02599014 0,10370194 ! regulation of axonogenesis GO:0050770 75 32 1,000 0,02599014 0,10353024 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,02599014 0,10335912 ! hindbrain development GO:0030902 61 32 1,000 0,02599014 0,10318856 ! gene silencing GO:0016458 65 32 1,000 0,02599014 0,10301856 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 0,02674914 0,10585269 ! DNA damage checkpoint GO:0000077 71 33 1,000 0,02752634 0,10874937 ! protein targeting to membrane GO:0006612 68 33 1,000 0,02752634 0,1085711 ! cell fate specification GO:0001708 52 33 1,000 0,02752634 0,1083934 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,02752634 0,10821629 ! negative regulation of transport GO:0051051 153 84 2,000 0,0284572 0,11169333 ! regulation of transmission of nerve impulse GO:0051969 141 84 2,000 0,0284572 0,11151142 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,02909822 0,11383793 ! mismatch repair GO:0006298 46 34 1,000 0,02909822 0,11365313 ! placenta development GO:0001890 53 34 1,000 0,02909822 0,11346893 ! response to inorganic substance GO:0010035 153 86 2,000 0,03022188 0,11765996 ! chromatin assembly GO:0031497 124 86 2,000 0,03022188 0,11746988 ! mitochondrion organization GO:0007005 148 86 2,000 0,03022188 0,11728041 ! regulation of muscle development GO:0048634 70 35 1,000 0,03070515 0,1189639 ! negative regulation of secretion GO:0051048 63 35 1,000 0,03070515 0,11877264 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,03070515 0,11858199 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,03070515 0,11839196 ! odontogenesis GO:0042476 66 35 1,000 0,03070515 0,11820253 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,03070515 0,11801371 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,03070515 0,11782549 ! neural tube formation GO:0001841 67 35 1,000 0,03070515 0,11763787 ! protein localization in nucleus GO:0034504 176 87 2,000 0,03112541 0,1190584 ! regulation of neurological system process GO:0031644 148 88 2,000 0,03204302 0,12237381 ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,03234646 0,12333691 ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,03234646 0,12314175 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 0,03234646 0,12294722 ! cellular defense response GO:0006968 114 89 2,000 0,03297468 0,12513735 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,03297468 0,12494028 ! regulation of cell cycle process GO:0010564 149 90 2,000 0,03392036 0,12832138 ! protein-DNA complex assembly GO:0065004 130 90 2,000 0,03392036 0,12811993 ! negative regulation of DNA binding GO:0043392 68 37 1,000 0,03402154 0,12830067 ! regulation of protein stability GO:0031647 73 37 1,000 0,03402154 0,12809989 ! glycogen metabolic process GO:0005977 61 37 1,000 0,03402154 0,12789973 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,03572976 0,134112 ! regulation of neuron projection development GO:0010975 91 38 1,000 0,03572976 0,13390311 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,03572976 0,13369486 ! embryonic epithelial tube formation GO:0001838 72 38 1,000 0,03572976 0,13348726 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 1,000 0,03572976 0,1332803 ! glucan metabolic process GO:0044042 62 38 1,000 0,03572976 0,13307399 GO:0006073|cellular glucan metabolic process, ! regulation of defense response GO:0031347 149 92 2,000 0,03585366 0,13332907 ! regulation of membrane potential GO:0042391 164 93 2,000 0,0368412 0,13679 ! negative regulation of multicellular organismal process GO:0051241 166 93 2,000 0,0368412 0,13657923 ! ear morphogenesis GO:0042471 60 39 1,000 0,03747049 0,13869847 ! segmentation GO:0035282 67 39 1,000 0,03747049 0,13848541 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 1,000 0,03747049 0,13827301 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,0385738 0,14212643 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,0385738 0,14190911 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,0385738 0,14169246 ! neuron fate determination GO:0048664 7 5 0,000 0,0385738 0,14147646 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0385738 0,14126112 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,0385738 0,14104644 ! polyol transport GO:0015791 12 5 0,000 0,0385738 0,14083241 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,0385738 0,14061903 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,0385738 0,14040629 ! response to superoxide GO:0000303 10 5 0,000 0,0385738 0,1401942 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,0385738 0,13998274 GO:0045940|positive regulation of steroid metabolic process, ! tongue development GO:0043586 8 5 0,000 0,0385738 0,13977193 ! female meiosis GO:0007143 7 5 0,000 0,0385738 0,13956174 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,0385738 0,13935219 ! cobalt ion transport GO:0006824 11 5 0,000 0,0385738 0,13914327 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,0385738 0,13893497 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,0385738 0,13872729 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,0385738 0,13852024 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,0385738 0,1383138 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,0385738 0,13810797 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,0385738 0,13790276 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,0385738 0,13769816 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,0385738 0,13749416 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,0385738 0,13729077 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,0385738 0,13708797 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0385738 0,13688578 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,0385738 0,13668418 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,0385738 0,13648317 ! negative chemotaxis GO:0050919 14 5 0,000 0,0385738 0,13628276 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,0385738 0,13608293 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,0385738 0,13588369 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,0385738 0,13568503 ! behavioral response to pain GO:0048266 9 5 0,000 0,0385738 0,13548695 ! clathrin coat assembly GO:0048268 14 5 0,000 0,0385738 0,13528944 ! Notch receptor processing GO:0007220 8 5 0,000 0,0385738 0,13509252 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0385738 0,13489616 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,0385738 0,13470037 ! micturition GO:0060073 9 5 0,000 0,0385738 0,13450516 ! copulation GO:0007620 9 5 0,000 0,0385738 0,1343105 ! glial cell fate commitment GO:0021781 13 5 0,000 0,0385738 0,13411641 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,0385738 0,13392288 ! spermidine metabolic process GO:0008216 7 5 0,000 0,0385738 0,13372991 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,0385738 0,13353749 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,0385738 0,13334563 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,0385738 0,13315432 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,0385738 0,13296355 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,0385738 0,13277333 ! grooming behavior GO:0007625 6 5 0,000 0,0385738 0,13258365 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,0385738 0,13239452 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,0385738 0,13220592 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0385738 0,13201786 ! lymph vessel development GO:0001945 10 5 0,000 0,0385738 0,13183034 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,0385738 0,13164335 ! endochondral ossification GO:0001958 16 5 0,000 0,0385738 0,13145688 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! parathyroid gland development GO:0060017 13 5 0,000 0,0385738 0,13127095 ! anagen GO:0042640 6 5 0,000 0,0385738 0,13108553 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,0385738 0,13090065 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,0385738 0,13071628 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,0385738 0,13053243 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,0385738 0,1303491 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,0385738 0,13016628 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,0385738 0,12998398 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,0385738 0,12980218 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,0385738 0,12962089 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,0385738 0,12944011 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,0385738 0,12925983 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,0385738 0,12908005 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,0385738 0,12890078 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,0385738 0,12872199 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,0385738 0,12854371 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,0385738 0,12836592 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,0385738 0,12818862 ! histidine catabolic process GO:0006548 6 5 0,000 0,0385738 0,1280118 GO:0009077|histidine family amino acid catabolic process, ! valine metabolic process GO:0006573 10 5 0,000 0,0385738 0,12783548 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,0385738 0,12765964 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,0385738 0,12748428 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,0385738 0,12730941 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,0385738 0,12713501 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,0385738 0,12696109 ! polyol catabolic process GO:0046174 7 5 0,000 0,0385738 0,12678765 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,0385738 0,12661468 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,0385738 0,12644218 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,0385738 0,12627015 ! muscle cell migration GO:0014812 8 5 0,000 0,0385738 0,12609858 ! mitochondrial fission GO:0000266 8 5 0,000 0,0385738 0,12592749 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,0385738 0,12575685 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,0385738 0,12558668 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,0385738 0,12541697 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,0385738 0,12524772 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,0385738 0,12507892 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,0385738 0,12491058 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,0385738 0,12474269 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,0385738 0,12457525 ! response to food GO:0032094 6 5 0,000 0,0385738 0,12440826 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,0385738 0,12424171 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,0385738 0,12407561 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0385738 0,12390996 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,0385738 0,12374474 ! forebrain neuron development GO:0021884 13 5 0,000 0,0385738 0,12357997 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,0385738 0,12341564 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,0385738 0,12325174 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0385738 0,12308827 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,0385738 0,12292524 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0385738 0,12276264 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,0385738 0,12260047 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,0385738 0,12243873 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,0385738 0,12227742 ! basic amino acid transport GO:0015802 11 5 0,000 0,0385738 0,12211652 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,0385738 0,12195606 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,0385738 0,12179601 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,0385738 0,12163638 ! depyrimidination GO:0045008 10 5 0,000 0,0385738 0,12147717 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,0385738 0,12131838 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,0385738 0,12116 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,0385738 0,12100203 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,0385738 0,12084448 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,0385738 0,12068733 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,0385738 0,1205306 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0385738 0,12037427 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,0385738 0,12021834 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,0385738 0,12006282 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,0385738 0,1199077 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,0385738 0,11975298 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,0385738 0,11959866 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0385738 0,11944473 ! response to arsenic GO:0046685 10 5 0,000 0,0385738 0,11929121 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,0385738 0,11913807 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,0385738 0,11898533 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,0385738 0,11883298 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,0385738 0,11868102 ! response to cadmium ion GO:0046686 7 5 0,000 0,0385738 0,11852945 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,0385738 0,11837826 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,0385738 0,11822746 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,0385738 0,11807705 ! decidualization GO:0046697 11 5 0,000 0,0385738 0,11792701 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,0385738 0,11777736 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,0385738 0,11762808 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,0385738 0,11747919 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,0385738 0,11733067 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,0385738 0,11718252 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,0385738 0,11703475 ! neural tube patterning GO:0021532 7 5 0,000 0,0385738 0,11688735 ! embryonic cleavage GO:0040016 6 5 0,000 0,0385738 0,11674032 ! peroxisome fission GO:0016559 5 5 0,000 0,0385738 0,11659367 ! histone demethylation GO:0016577 10 5 0,000 0,0385738 0,11644738 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,0385738 0,11630145 ! mitotic recombination GO:0006312 9 5 0,000 0,0385738 0,11615589 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,0385738 0,1160107 ! metaphase plate congression GO:0051310 7 5 0,000 0,0385738 0,11586587 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0385738 0,11572139 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,0385738 0,11557728 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,0385738 0,11543353 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,0385738 0,11529013 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,0385738 0,11514709 ! muscle cell proliferation GO:0033002 11 5 0,000 0,0385738 0,11500441 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,0385738 0,11486208 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,0385738 0,1147201 ! plasminogen activation GO:0031639 5 5 0,000 0,0385738 0,11457847 ! B cell homeostasis GO:0001782 13 5 0,000 0,0385738 0,11443719 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,0385738 0,11429625 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,0385738 0,11415567 ! metaphase GO:0051323 8 5 0,000 0,0385738 0,11401543 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,0385738 0,11387553 ! cellular response to nutrient GO:0031670 8 5 0,000 0,0385738 0,11373598 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,0385738 0,11359677 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,0385738 0,1134579 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,0385738 0,11331936 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,0385738 0,11318117 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,0385738 0,11304331 ! response to redox state GO:0051775 5 5 0,000 0,0385738 0,11290579 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,0385738 0,1127686 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,0385738 0,11263175 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,0385738 0,11249522 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,0385738 0,11235903 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0385738 0,11222317 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,0385738 0,11208763 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0385738 0,11195242 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,0385738 0,11181754 ! striatum development GO:0021756 9 5 0,000 0,0385738 0,11168298 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,0385738 0,11154875 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,0385738 0,11141484 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,0385738 0,11128125 ! glial cell migration GO:0008347 11 5 0,000 0,0385738 0,11114797 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,0385738 0,11101502 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,0385738 0,11088239 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,0385738 0,11075007 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,0385738 0,11061807 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,0385738 0,11048638 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,0385738 0,110355 ! neuroprotection GO:0043526 6 5 0,000 0,0385738 0,11022394 ! neural plate development GO:0001840 8 5 0,000 0,0385738 0,11009319 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,0385738 0,10996275 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,0385738 0,10983261 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,0385738 0,10970279 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,0385738 0,10957327 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,0385738 0,10944405 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,0385738 0,10931515 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,0385738 0,10918654 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,0385738 0,10905824 ! spindle assembly GO:0051225 6 5 0,000 0,0385738 0,10893023 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,0385738 0,10880253 GO:0016226|iron-sulfur cluster assembly, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,0385738 0,10867513 ! drug metabolic process GO:0017144 6 5 0,000 0,0385738 0,10854802 ! phospholipid scrambling GO:0017121 8 5 0,000 0,0385738 0,10842121 ! carnitine metabolic process GO:0009437 7 5 0,000 0,0385738 0,1082947 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,0385738 0,10816848 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,0385738 0,10804256 ! forebrain development GO:0030900 188 95 2,000 0,03885784 0,10871159 ! regulation of hormone secretion GO:0046883 62 40 1,000 0,03924314 0,10966201 ! feeding behavior GO:0007631 59 40 1,000 0,03924314 0,10953479 ! negative regulation of binding GO:0051100 72 40 1,000 0,03924314 0,10940787 ! mesenchymal cell development GO:0014031 87 40 1,000 0,03924314 0,10928124 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of protein location GO:0045185 91 40 1,000 0,03924314 0,1091549 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 1,000 0,04104709 0,11404076 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 0,04288176 0,11900058 ! regulation of leukocyte mediated immunity GO:0002703 79 42 1,000 0,04288176 0,11886349 ! neuron migration GO:0001764 79 42 1,000 0,04288176 0,11872671 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 2,000 0,04305616 0,11907255 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,04305616 0,11893584 GO:0060538|skeletal muscle organ development, ! epithelial cell differentiation GO:0030855 79 43 1,000 0,04474655 0,12346353 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 0,04474655 0,1233221 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,04474655 0,123181 ! glucose transport GO:0015758 65 43 1,000 0,04474655 0,12304022 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,04474655 0,12289976 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,04610889 0,12649713 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,04610889 0,12635305 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,04610889 0,12620931 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04610889 0,12606589 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,04610889 0,12592279 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,04610889 0,12578002 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,04610889 0,12563758 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,04610889 0,12549545 ! sleep GO:0030431 13 6 0,000 0,04610889 0,12535365 ! response to oxygen radical GO:0000305 11 6 0,000 0,04610889 0,12521217 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,04610889 0,125071 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,04610889 0,12493016 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,04610889 0,12478963 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,04610889 0,12464942 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,04610889 0,12450952 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,04610889 0,12436993 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,04610889 0,12423066 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,04610889 0,1240917 ! response to zinc ion GO:0010043 9 6 0,000 0,04610889 0,12395305 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,04610889 0,12381471 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,04610889 0,12367668 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,04610889 0,12353895 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,04610889 0,12340154 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,04610889 0,12326442 ! malate metabolic process GO:0006108 11 6 0,000 0,04610889 0,12312762 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,04610889 0,12299111 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,04610889 0,12285491 ! protein refolding GO:0042026 15 6 0,000 0,04610889 0,12271901 ! opsonization GO:0008228 8 6 0,000 0,04610889 0,1225834 ! mating behavior GO:0007617 7 6 0,000 0,04610889 0,1224481 ! neuron remodeling GO:0016322 15 6 0,000 0,04610889 0,1223131 ! equilibrioception GO:0050957 14 6 0,000 0,04610889 0,12217839 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,04610889 0,12204398 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,04610889 0,12190987 ! photoreceptor cell development GO:0042461 10 6 0,000 0,04610889 0,12177605 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,04610889 0,12164252 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,04610889 0,12150929 ! response to interferon-gamma GO:0034341 15 6 0,000 0,04610889 0,12137635 ! toxin metabolic process GO:0009404 11 6 0,000 0,04610889 0,1212437 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,04610889 0,12111133 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04610889 0,12097926 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,04610889 0,12084747 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,04610889 0,12071598 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,04610889 0,12058476 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,04610889 0,12045383 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,04610889 0,12032319 ! thymic T cell selection GO:0045061 12 6 0,000 0,04610889 0,12019283 ! protein lipoylation GO:0009249 10 6 0,000 0,04610889 0,12006275 ! cysteine metabolic process GO:0006534 10 6 0,000 0,04610889 0,11993295 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,04610889 0,11980344 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04610889 0,1196742 ! glutamate catabolic process GO:0006538 10 6 0,000 0,04610889 0,11954524 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,04610889 0,11941656 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,04610889 0,11928815 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,04610889 0,11916002 ! response to pH GO:0009268 10 6 0,000 0,04610889 0,11903217 ! hyperosmotic response GO:0006972 9 6 0,000 0,04610889 0,11890459 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,04610889 0,11877728 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,04610889 0,11865025 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,04610889 0,11852348 ! urea metabolic process GO:0019627 7 6 0,000 0,04610889 0,11839699 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,04610889 0,11827077 ! neutrophil activation GO:0042119 8 6 0,000 0,04610889 0,11814481 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,04610889 0,11801913 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,04610889 0,11789371 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,04610889 0,11776856 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04610889 0,11764367 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,04610889 0,11751905 ! neuron apoptosis GO:0051402 9 6 0,000 0,04610889 0,11739469 ! nucleoside salvage GO:0043174 9 6 0,000 0,04610889 0,11727059 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,04610889 0,11714676 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,04610889 0,11702319 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,04610889 0,11689987 ! carnitine transport GO:0015879 10 6 0,000 0,04610889 0,11677682 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,04610889 0,11665403 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,04610889 0,11653149 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,04610889 0,11640921 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,04610889 0,11628719 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,04610889 0,11616543 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,04610889 0,11604391 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,04610889 0,11592266 ! establishment of spindle localization GO:0051293 12 6 0,000 0,04610889 0,11580165 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,04610889 0,1156809 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,04610889 0,1155604 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,04610889 0,11544015 ! response to UV-C GO:0010225 11 6 0,000 0,04610889 0,11532015 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,04610889 0,1152004 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,04610889 0,11508089 ! interaction with symbiont GO:0051702 13 6 0,000 0,04610889 0,11496164 ! regulation of dendrite development GO:0050773 16 6 0,000 0,04610889 0,11484263 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04610889 0,11472387 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,04610889 0,11460535 ! response to copper ion GO:0046688 10 6 0,000 0,04610889 0,11448708 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,04610889 0,11436905 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04610889 0,11425127 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04610889 0,11413373 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,04610889 0,11401642 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,04610889 0,11389936 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,04610889 0,11378254 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,04610889 0,11366596 ! hair follicle maturation GO:0048820 7 6 0,000 0,04610889 0,11354962 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,04610889 0,11343352 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,04610889 0,11331765 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04610889 0,11320202 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,04610889 0,11308663 ! subpallium development GO:0021544 10 6 0,000 0,04610889 0,11297147 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,04610889 0,11285654 ! histone ubiquitination GO:0016574 8 6 0,000 0,04610889 0,11274185 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,04610889 0,11262739 ! maintenance of organ identity GO:0048496 9 6 0,000 0,04610889 0,11251317 ! G2 phase GO:0051319 16 6 0,000 0,04610889 0,11239917 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,04610889 0,11228541 ! establishment of planar polarity GO:0001736 7 6 0,000 0,04610889 0,11217187 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,04610889 0,11205857 ! membrane to membrane docking GO:0022614 14 6 0,000 0,04610889 0,11194549 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,04610889 0,11183264 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,04610889 0,11172002 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,04610889 0,11160763 ! receptor internalization GO:0031623 10 6 0,000 0,04610889 0,11149546 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,04610889 0,11138352 GO:0031272|regulation of pseudopodium assembly, ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,04610889 0,1112718 GO:0043011|myeloid dendritic cell differentiation, ! protein deubiquitination GO:0016579 14 6 0,000 0,04610889 0,1111603 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,04610889 0,11104903 ! protein destabilization GO:0031648 9 6 0,000 0,04610889 0,11093798 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,04610889 0,11082715 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,04610889 0,11071655 ! regulation of viral transcription GO:0046782 10 6 0,000 0,04610889 0,11060616 ! progesterone metabolic process GO:0042448 10 6 0,000 0,04610889 0,110496 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,04610889 0,11038605 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,04610889 0,11027632 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,04610889 0,11016681 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,04610889 0,11005752 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,04610889 0,10994845 ! determination of adult lifespan GO:0008340 15 6 0,000 0,04610889 0,10983959 ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,04610889 0,10973094 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,04610889 0,10962251 ! catecholamine transport GO:0051937 9 6 0,000 0,04610889 0,1095143 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,04610889 0,10940629 ! sensory cilium assembly GO:0035058 10 6 0,000 0,04610889 0,1092985 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,04610889 0,10919093 ! maternal placenta development GO:0001893 12 6 0,000 0,04610889 0,10908356 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,04610889 0,10897641 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,04610889 0,10886946 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,04610889 0,10876273 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04610889 0,1086562 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,04610889 0,10854988 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,04610889 0,10844377 ! hexose transport GO:0008645 67 44 1,000 0,04664088 0,10958786 GO:0015749|monosaccharide transport, ! biopolymer methylation GO:0043414 84 44 1,000 0,04664088 0,10948094 ! developmental growth GO:0048589 82 44 1,000 0,04664088 0,10937424 ! maintenance of location in cell GO:0051651 97 44 1,000 0,04664088 0,10926774 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,04856419 0,11366288 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 1,000 0,04856419 0,11355242 ! vascular process in circulatory system GO:0003018 80 47 1,000 0,05249546 0,12262532 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,05249546 0,12250638 ! methylation GO:0032259 90 47 1,000 0,05249546 0,12238768 ! protein homooligomerization GO:0051260 76 47 1,000 0,05249546 0,1222692 ! tRNA transcription GO:0009304 14 7 0,000 0,05358517 0,12468657 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,05358517 0,1245661 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,05358517 0,12444586 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,05358517 0,12432586 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,05358517 0,12420608 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,05358517 0,12408654 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,05358517 0,12396722 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,05358517 0,12384814 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,05358517 0,12372928 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,05358517 0,12361066 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,05358517 0,12349225 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,05358517 0,12337408 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,05358517 0,12325613 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,05358517 0,12313841 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,05358517 0,12302091 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,05358517 0,12290364 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,05358517 0,12278658 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,05358517 0,12266976 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,05358517 0,12255315 ! glycolipid transport GO:0046836 10 7 0,000 0,05358517 0,12243677 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,05358517 0,1223206 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,05358517 0,12220466 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,05358517 0,12208893 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,05358517 0,12197343 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,05358517 0,12185814 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,05358517 0,12174307 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,05358517 0,12162822 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,05358517 0,12151359 ! pericardium development GO:0060039 14 7 0,000 0,05358517 0,12139917 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,05358517 0,12128496 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,05358517 0,12117097 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,05358517 0,1210572 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,05358517 0,12094363 ! lipoprotein transport GO:0042953 14 7 0,000 0,05358517 0,12083028 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,05358517 0,12071715 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,05358517 0,12060422 ! rhythmic behavior GO:0007622 15 7 0,000 0,05358517 0,12049151 ! estrogen metabolic process GO:0008210 17 7 0,000 0,05358517 0,120379 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,05358517 0,12026671 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,05358517 0,12015463 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,05358517 0,12004275 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,05358517 0,11993108 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,05358517 0,11981962 ! mechanosensory behavior GO:0007638 14 7 0,000 0,05358517 0,11970837 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,05358517 0,11959732 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,05358517 0,11948648 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,05358517 0,11937585 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,05358517 0,11926542 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,05358517 0,11915519 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,05358517 0,11904517 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,05358517 0,11893534 ! adrenal gland development GO:0030325 17 7 0,000 0,05358517 0,11882573 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,05358517 0,11871631 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,05358517 0,1186071 ! ovulation GO:0030728 9 7 0,000 0,05358517 0,11849808 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,05358517 0,11838927 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,05358517 0,11828065 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,05358517 0,11817224 ! microtubule nucleation GO:0007020 20 7 0,000 0,05358517 0,11806402 ! proline biosynthetic process GO:0006561 10 7 0,000 0,05358517 0,11795601 ! thyroid hormone generation GO:0006590 13 7 0,000 0,05358517 0,11784818 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,05358517 0,11774056 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,05358517 0,11763313 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,05358517 0,1175259 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,05358517 0,11741886 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,05358517 0,11731202 ! galactose metabolic process GO:0006012 13 7 0,000 0,05358517 0,11720538 ! vesicle fusion GO:0006906 17 7 0,000 0,05358517 0,11709892 ! response to dietary excess GO:0002021 8 7 0,000 0,05358517 0,11699266 ! intracellular pH reduction GO:0051452 11 7 0,000 0,05358517 0,11688659 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,05358517 0,11678072 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,05358517 0,11667504 ! organ growth GO:0035265 15 7 0,000 0,05358517 0,11656954 ! purine salvage GO:0043101 10 7 0,000 0,05358517 0,11646424 ! nucleoside transport GO:0015858 8 7 0,000 0,05358517 0,11635913 ! parturition GO:0007567 14 7 0,000 0,05358517 0,11625421 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,05358517 0,11614947 ! rRNA modification GO:0000154 14 7 0,000 0,05358517 0,11604493 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,05358517 0,11594057 ! spindle checkpoint GO:0031577 15 7 0,000 0,05358517 0,1158364 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,05358517 0,11573242 ! macrophage differentiation GO:0030225 11 7 0,000 0,05358517 0,11562862 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,05358517 0,11552501 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,05358517 0,11542159 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,05358517 0,11531835 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,05358517 0,11521529 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,05358517 0,11511242 ! fibrinolysis GO:0042730 10 7 0,000 0,05358517 0,11500974 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,05358517 0,11490723 ! eating behavior GO:0042755 7 7 0,000 0,05358517 0,11480491 ! B cell lineage commitment GO:0002326 21 7 0,000 0,05358517 0,11470277 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,05358517 0,11460081 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,05358517 0,11449904 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,05358517 0,11439744 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,05358517 0,11429602 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,05358517 0,11419479 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,05358517 0,11409373 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,05358517 0,11399285 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,05358517 0,11389215 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,05358517 0,11379163 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,05358517 0,11369128 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,05358517 0,11359111 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,05358517 0,11349112 ! regulation of meiosis GO:0040020 12 7 0,000 0,05358517 0,1133913 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,05358517 0,11329166 ! T cell lineage commitment GO:0002360 16 7 0,000 0,05358517 0,1131922 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,05358517 0,11309291 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,05358517 0,11299379 ! transcription termination GO:0006353 13 7 0,000 0,05358517 0,11289485 ! response to tumor cell GO:0002347 13 7 0,000 0,05358517 0,11279608 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,05358517 0,11269748 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,05358517 0,11259905 ! anaphase GO:0051322 17 7 0,000 0,05358517 0,1125008 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,05358517 0,11240271 ! axonal fasciculation GO:0007413 18 7 0,000 0,05358517 0,1123048 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,05358517 0,11220706 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,05358517 0,11210949 ! diuresis GO:0030146 12 7 0,000 0,05358517 0,11201209 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,05358517 0,11191486 ! thiamin metabolic process GO:0006772 7 7 0,000 0,05358517 0,11181779 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,05358517 0,1117209 ! antibiotic transport GO:0042891 9 7 0,000 0,05358517 0,11162417 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,05358517 0,11152761 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,05358517 0,11143121 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,05358517 0,11133499 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,05358517 0,11123892 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,05358517 0,11114303 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,05358517 0,1110473 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,05358517 0,11095173 ! lymph node development GO:0048535 10 7 0,000 0,05358517 0,11085633 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,05358517 0,11076109 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,05358517 0,11066602 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,05358517 0,11057111 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,05358517 0,11047636 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,05358517 0,11038178 ! adult feeding behavior GO:0008343 9 7 0,000 0,05358517 0,11028735 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,05358517 0,11019309 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,05358517 0,11009899 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,05358517 0,11000505 ! muscle adaptation GO:0043500 14 7 0,000 0,05358517 0,10991126 ! embryonic heart tube development GO:0035050 10 7 0,000 0,05358517 0,10981764 ! retina homeostasis GO:0001895 12 7 0,000 0,05358517 0,10972418 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,05358517 0,10963088 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,05358517 0,10953773 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,05358517 0,10944475 ! protein prenylation GO:0018342 18 7 0,000 0,05358517 0,10935192 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,05358517 0,10925925 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,05358517 0,10916673 ! morphogenesis of embryonic epithelium GO:0016331 91 48 1,000 0,05450232 0,11094126 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,05450232 0,11084748 ! regulation of inflammatory response GO:0050727 75 48 1,000 0,05450232 0,11075386 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 0,05653592 0,11478938 ! peptide metabolic process GO:0006518 76 49 1,000 0,05653592 0,1146926 ! response to temperature stimulus GO:0009266 76 49 1,000 0,05653592 0,11459597 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,05653592 0,11449951 ! regulation of cell projection organization GO:0031344 121 50 1,000 0,05859573 0,11857135 ! regulation of ossification GO:0030278 117 50 1,000 0,05859573 0,11847171 ! regulation of gene expression, epigenetic GO:0040029 105 50 1,000 0,05859573 0,11837223 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 1,000 0,06068122 0,12248241 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,0610031 0,12302888 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,0610031 0,12292584 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,0610031 0,12282298 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,0610031 0,12272028 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,0610031 0,12261776 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,0610031 0,12251541 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,0610031 0,12241322 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,0610031 0,12231121 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,0610031 0,12220937 ! meiotic prophase I GO:0007128 13 8 0,000 0,0610031 0,1221077 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,0610031 0,1220062 ! oligopeptide transport GO:0006857 15 8 0,000 0,0610031 0,12190486 ! UTP metabolic process GO:0046051 8 8 0,000 0,0610031 0,1218037 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,0610031 0,1217027 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,0610031 0,12160187 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,0610031 0,1215012 ! succinate metabolic process GO:0006105 14 8 0,000 0,0610031 0,12140071 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,0610031 0,12130038 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,0610031 0,12120021 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,0610031 0,12110021 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,0610031 0,12100038 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,0610031 0,1209007 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,0610031 0,1208012 ! reflex GO:0060004 16 8 0,000 0,0610031 0,12070185 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,0610031 0,12060268 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,0610031 0,12050366 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,0610031 0,1204048 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,0610031 0,12030611 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,0610031 0,12020758 ! pigment granule organization GO:0048753 16 8 0,000 0,0610031 0,12010921 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,0610031 0,120011 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,0610031 0,11991295 ! histidine metabolic process GO:0006547 16 8 0,000 0,0610031 0,11981507 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,0610031 0,11971734 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,0610031 0,11961977 ! glycine catabolic process GO:0006546 13 8 0,000 0,0610031 0,11952236 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,0610031 0,11942511 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,0610031 0,11932801 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,0610031 0,11923108 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,0610031 0,1191343 ! melanin metabolic process GO:0006582 15 8 0,000 0,0610031 0,11903768 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,0610031 0,11894121 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,0610031 0,1188449 ! macrophage activation GO:0042116 12 8 0,000 0,0610031 0,11874875 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,0610031 0,11865275 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,0610031 0,11855691 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,0610031 0,11846122 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,0610031 0,11836569 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,0610031 0,11827031 ! osteoblast development GO:0002076 16 8 0,000 0,0610031 0,11817508 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,0610031 0,11808001 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,0610031 0,11798509 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,0610031 0,11789033 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,0610031 0,11779571 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,0610031 0,11770125 ! response to UV-B GO:0010224 16 8 0,000 0,0610031 0,11760694 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,0610031 0,11751277 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,0610031 0,11741876 ! intermediate filament organization GO:0045109 12 8 0,000 0,0610031 0,1173249 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,0610031 0,11723119 ! cellular extravasation GO:0045123 12 8 0,000 0,0610031 0,11713763 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,0610031 0,11704422 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,0610031 0,11695096 ! response to antibiotic GO:0046677 11 8 0,000 0,0610031 0,11685785 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,0610031 0,11676488 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,0610031 0,11667206 ! DNA topological change GO:0006265 12 8 0,000 0,0610031 0,11657939 ! response to tropane GO:0014073 15 8 0,000 0,0610031 0,11648687 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,0610031 0,11639449 ! melanosome transport GO:0032402 13 8 0,000 0,0610031 0,11630226 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,0610031 0,11621018 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,0610031 0,11611824 ! mast cell activation GO:0045576 14 8 0,000 0,0610031 0,11602645 ! multicellular organismal aging GO:0010259 18 8 0,000 0,0610031 0,1159348 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,0610031 0,1158433 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,0610031 0,11575194 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,0610031 0,11566072 ! nucleosome disassembly GO:0006337 14 8 0,000 0,0610031 0,11556965 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,0610031 0,11547872 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,0610031 0,11538794 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,0610031 0,11529729 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,0610031 0,11520679 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,0610031 0,11511644 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,0610031 0,11502622 ! intracellular lipid transport GO:0032365 13 8 0,000 0,0610031 0,11493614 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,0610031 0,11484621 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of macrophage activation GO:0043030 15 8 0,000 0,0610031 0,11475642 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,0610031 0,11466676 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,0610031 0,11457725 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,0610031 0,11448787 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,0610031 0,11439864 ! hormone catabolic process GO:0042447 17 8 0,000 0,0610031 0,11430954 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,0610031 0,11422059 GO:0010828|positive regulation of glucose transport, ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,0610031 0,11413177 ! ATP catabolic process GO:0006200 11 8 0,000 0,0610031 0,11404309 ! blastocyst growth GO:0001832 19 8 0,000 0,0610031 0,11395455 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,0610031 0,11386614 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,0610031 0,11377787 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,0610031 0,11368974 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,0610031 0,11360175 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,0610031 0,11351389 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,0610031 0,11342616 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,0610031 0,11333858 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,0610031 0,11325112 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,0610031 0,11316381 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,0610031 0,11307662 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,0610031 0,11298957 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,0610031 0,11290266 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,0610031 0,11281588 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,0610031 0,11272923 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,0610031 0,11264271 ! positive regulation of growth GO:0045927 90 52 1,000 0,06279187 0,11585678 ! cartilage development GO:0051216 90 52 1,000 0,06279187 0,115768 ! synapse organization GO:0050808 85 52 1,000 0,06279187 0,11567936 ! regulation of translational initiation GO:0006446 82 53 1,000 0,06492715 0,1195216 ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,06708656 0,12340234 ! cell recognition GO:0008037 85 54 1,000 0,06708656 0,12330807 ! regulation of developmental growth GO:0048638 15 9 0,000 0,06836313 0,12555855 ! axon extension GO:0048675 15 9 0,000 0,06836313 0,12546277 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,06836313 0,12536715 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,06836313 0,12527167 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,06836313 0,12517633 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,06836313 0,12508114 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,06836313 0,12498609 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,06836313 0,12489119 ! phosphate transport GO:0006817 19 9 0,000 0,06836313 0,12479643 ! reproductive behavior GO:0019098 19 9 0,000 0,06836313 0,12470182 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,06836313 0,12460735 ! CTP metabolic process GO:0046036 9 9 0,000 0,06836313 0,12451302 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,06836313 0,12441883 ! GTP metabolic process GO:0046039 9 9 0,000 0,06836313 0,12432479 ! RNA methylation GO:0001510 15 9 0,000 0,06836313 0,12423089 ! elastic fiber assembly GO:0048251 15 9 0,000 0,06836313 0,12413713 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,06836313 0,12404351 ! artery development GO:0060840 24 9 0,000 0,06836313 0,12395004 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,06836313 0,1238567 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,06836313 0,1237635 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,06836313 0,12367045 ! chemosensory behavior GO:0007635 20 9 0,000 0,06836313 0,12357753 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,06836313 0,12348476 ! leukocyte degranulation GO:0043299 16 9 0,000 0,06836313 0,12339212 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,06836313 0,12329962 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,06836313 0,12320726 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,06836313 0,12311504 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,06836313 0,12302296 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,06836313 0,12293101 ! protein targeting to ER GO:0045047 22 9 0,000 0,06836313 0,12283921 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,06836313 0,12274754 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,06836313 0,122656 ! T cell selection GO:0045058 23 9 0,000 0,06836313 0,1225646 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,06836313 0,12247334 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,06836313 0,12238222 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,06836313 0,12229123 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,06836313 0,12220037 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,06836313 0,12210965 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,06836313 0,12201906 ! mannose metabolic process GO:0006013 13 9 0,000 0,06836313 0,12192861 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,06836313 0,12183829 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,06836313 0,12174811 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,06836313 0,12165806 ! receptor clustering GO:0043113 18 9 0,000 0,06836313 0,12156814 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,06836313 0,12147836 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,06836313 0,12138871 ! ruffle organization GO:0031529 15 9 0,000 0,06836313 0,12129919 ! retinol metabolic process GO:0042572 18 9 0,000 0,06836313 0,1212098 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,06836313 0,12112054 ! behavioral fear response GO:0001662 22 9 0,000 0,06836313 0,12103142 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,06836313 0,12094242 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,06836313 0,12085356 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,06836313 0,12076483 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,06836313 0,12067623 ! oligodendrocyte development GO:0014003 10 9 0,000 0,06836313 0,12058775 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,06836313 0,12049941 ! segment specification GO:0007379 13 9 0,000 0,06836313 0,1204112 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,06836313 0,12032311 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,06836313 0,12023516 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,06836313 0,12014733 ! response to amine stimulus GO:0014075 13 9 0,000 0,06836313 0,12005963 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,06836313 0,11997206 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,06836313 0,11988462 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,06836313 0,1197973 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,06836313 0,11971011 ! renal water homeostasis GO:0003091 14 9 0,000 0,06836313 0,11962305 ! postreplication repair GO:0006301 22 9 0,000 0,06836313 0,11953612 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,06836313 0,11944931 ! icosanoid secretion GO:0032309 15 9 0,000 0,06836313 0,11936263 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,06836313 0,11927607 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,06836313 0,11918964 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,06836313 0,11910333 ! regulation of cell division GO:0051302 15 9 0,000 0,06836313 0,11901715 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,06836313 0,11893109 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,06836313 0,11884516 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,06836313 0,11875935 ! sterol catabolic process GO:0016127 11 9 0,000 0,06836313 0,11867366 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,06836313 0,1185881 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,06836313 0,11850266 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,06836313 0,11841735 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,06836313 0,11833216 GO:0000084|S phase of mitotic cell cycle, ! musculoskeletal movement GO:0050881 14 9 0,000 0,06836313 0,11824709 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,06836313 0,11816214 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,06836313 0,11807731 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,06836313 0,11799261 ! purine base metabolic process GO:0006144 21 9 0,000 0,06836313 0,11790803 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,06836313 0,11782357 ! pigment granule transport GO:0051904 17 9 0,000 0,06836313 0,11773923 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,06836313 0,11765501 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,06836313 0,11757091 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,06836313 0,11748693 ! mitochondrion localization GO:0051646 15 9 0,000 0,06836313 0,11740307 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,06926958 0,11887491 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,06926958 0,11879018 ! aging GO:0007568 103 55 1,000 0,06926958 0,11870557 ! heart morphogenesis GO:0003007 97 55 1,000 0,06926958 0,11862108 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,06926958 0,11853671 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,07147573 0,12222502 ! regulation of DNA replication GO:0006275 101 56 1,000 0,07147573 0,12213821 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,07147573 0,12205153 ! muscle fiber development GO:0048747 112 57 1,000 0,0737045 0,1257681 ! maintenance of location GO:0051235 118 57 1,000 0,0737045 0,12567897 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,07566572 0,12893182 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,07566572 0,12884057 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,07566572 0,12874945 ! synapsis GO:0007129 13 10 0,000 0,07566572 0,12865846 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,07566572 0,1285676 ! N-glycan processing GO:0006491 20 10 0,000 0,07566572 0,12847687 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,07566572 0,12838626 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,07566572 0,12829579 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,07566572 0,12820544 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,07566572 0,12811522 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,07566572 0,12802512 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,07566572 0,12793515 GO:0048200|Golgi transport vesicle coating, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,07566572 0,12784531 ! androgen metabolic process GO:0008209 17 10 0,000 0,07566572 0,1277556 ! phospholipid efflux GO:0033700 16 10 0,000 0,07566572 0,127666 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,07566572 0,12757654 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,07566572 0,1274872 ! pathogenesis GO:0009405 13 10 0,000 0,07566572 0,12739799 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,07566572 0,1273089 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,07566572 0,12721993 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,07566572 0,12713109 ! endoderm development GO:0007492 16 10 0,000 0,07566572 0,12704237 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,07566572 0,12695378 ! arginine catabolic process GO:0006527 13 10 0,000 0,07566572 0,12686531 ! proline metabolic process GO:0006560 13 10 0,000 0,07566572 0,12677697 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,07566572 0,12668874 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,07566572 0,12660064 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,07566572 0,12651266 ! V(D)J recombination GO:0033151 28 10 0,000 0,07566572 0,12642481 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,07566572 0,12633707 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,07566572 0,12624946 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,07566572 0,12616197 ! B cell proliferation GO:0042100 18 10 0,000 0,07566572 0,1260746 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,07566572 0,12598735 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,07566572 0,12590022 ! multicellular organism growth GO:0035264 18 10 0,000 0,07566572 0,12581322 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,07566572 0,12572633 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,07566572 0,12563956 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,07566572 0,12555291 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,07566572 0,12546638 ! macroautophagy GO:0016236 17 10 0,000 0,07566572 0,12537997 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,07566572 0,12529368 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,07566572 0,12520751 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,07566572 0,12512146 ! copper ion homeostasis GO:0055070 13 10 0,000 0,07566572 0,12503552 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,07566572 0,12494971 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,07566572 0,12486401 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,07566572 0,12477843 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,07566572 0,12469296 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,07566572 0,12460761 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,07566572 0,12452238 ! blastoderm segmentation GO:0007350 18 10 0,000 0,07566572 0,12443727 ! response to dsRNA GO:0043331 20 10 0,000 0,07566572 0,12435227 ! DNA ligation GO:0006266 19 10 0,000 0,07566572 0,12426739 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,07566572 0,12418262 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,07566572 0,12409797 ! melanosome localization GO:0032400 16 10 0,000 0,07566572 0,12401344 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,07566572 0,12392901 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,07566572 0,12384471 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,07566572 0,12376052 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,07566572 0,12367644 ! mRNA cleavage GO:0006379 17 10 0,000 0,07566572 0,12359248 ! protein sumoylation GO:0016925 15 10 0,000 0,07566572 0,12350863 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,07566572 0,1234249 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,07566572 0,12334128 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,07566572 0,12325777 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,07566572 0,12317437 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,07566572 0,12309109 ! prophase GO:0051324 15 10 0,000 0,07566572 0,12300792 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,07566572 0,12292486 ! apical protein localization GO:0045176 15 10 0,000 0,07566572 0,12284192 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,07566572 0,12275908 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! midbrain development GO:0030901 13 10 0,000 0,07566572 0,12267636 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,07566572 0,12259375 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,07566572 0,12251125 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,07566572 0,12242887 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,07566572 0,12234659 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,07566572 0,12226442 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,07566572 0,12218236 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,07566572 0,12210042 ! oocyte development GO:0048599 17 10 0,000 0,07566572 0,12201858 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,07566572 0,12193685 ! blastocyst formation GO:0001825 17 10 0,000 0,07566572 0,12185524 ! cerebellar cortex development GO:0021695 15 10 0,000 0,07566572 0,12177373 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,07566572 0,12169233 ! activation of innate immune response GO:0002218 12 10 0,000 0,07566572 0,12161104 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,07566572 0,12152986 GO:0042267|natural killer cell mediated cytotoxicity, ! establishment of cell polarity GO:0030010 16 10 0,000 0,07566572 0,12144878 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,07566572 0,12136782 ! adult behavior GO:0030534 99 58 1,000 0,07595541 0,12175131 ! integrin-mediated signaling pathway GO:0007229 135 59 1,000 0,07822798 0,1253106 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,08052173 0,12889906 ! camera-type eye development GO:0043010 116 60 1,000 0,08052173 0,12881336 ! respiratory burst GO:0045730 17 11 0,000 0,08291131 0,13254791 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,08291131 0,1324599 ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,08291131 0,132372 ! thyroid gland development GO:0030878 26 11 0,000 0,08291131 0,13228422 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,08291131 0,13219656 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,08291131 0,13210901 ! response to pain GO:0048265 24 11 0,000 0,08291131 0,13202158 ! bone resorption GO:0045453 16 11 0,000 0,08291131 0,13193426 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,08291131 0,13184706 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,08291131 0,13175998 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,08291131 0,13167301 ! syncytium formation GO:0006949 18 11 0,000 0,08291131 0,13158615 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,08291131 0,13149941 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,08291131 0,13141278 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,08291131 0,13132627 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,08291131 0,13123987 ! lipid digestion GO:0044241 18 11 0,000 0,08291131 0,13115359 ! UV protection GO:0009650 19 11 0,000 0,08291131 0,13106741 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,08291131 0,13098136 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,08291131 0,13089541 ! temperature homeostasis GO:0001659 17 11 0,000 0,08291131 0,13080958 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,08291131 0,13072386 ! negative regulation of ossification GO:0030279 26 11 0,000 0,08291131 0,13063825 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,08291131 0,13055275 ! regulation of organ growth GO:0046620 13 11 0,000 0,08291131 0,13046737 ! pigment granule localization GO:0051875 20 11 0,000 0,08291131 0,1303821 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,08291131 0,13029693 ! vasoconstriction GO:0042310 18 11 0,000 0,08291131 0,13021188 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,08291131 0,13012694 ! embryonic axis specification GO:0000578 18 11 0,000 0,08291131 0,13004212 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,08291131 0,1299574 ! snRNA metabolic process GO:0016073 24 11 0,000 0,08291131 0,12987279 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,08291131 0,12978829 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,08291131 0,1297039 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,08291131 0,12961963 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,08291131 0,12953546 ! zymogen activation GO:0031638 15 11 0,000 0,08291131 0,1294514 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,08291131 0,12936745 ! neuroblast proliferation GO:0007405 24 11 0,000 0,08291131 0,12928361 ! nucleosome positioning GO:0016584 15 11 0,000 0,08291131 0,12919987 ! regulation of isotype switching GO:0045191 22 11 0,000 0,08291131 0,12911625 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,08291131 0,12903273 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,08291131 0,12894932 ! acid secretion GO:0046717 18 11 0,000 0,08291131 0,12886602 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,08291131 0,12878283 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,08291131 0,12869975 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,08291131 0,12861677 ! oocyte differentiation GO:0009994 18 11 0,000 0,08291131 0,1285339 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,08291131 0,12845113 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,08291131 0,12836847 ! cholesterol efflux GO:0033344 19 11 0,000 0,08291131 0,12828592 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,08291131 0,12820347 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,08291131 0,12812113 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,08291131 0,1280389 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,08291131 0,12795677 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,08291131 0,12787475 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,08291131 0,12779283 ! defense response to fungus GO:0050832 13 11 0,000 0,08291131 0,12771102 ! developmental induction GO:0031128 19 11 0,000 0,08291131 0,12762931 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,08291131 0,1275477 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,08291131 0,1274662 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,08291131 0,12738481 ! sequestering of metal ion GO:0051238 14 11 0,000 0,08291131 0,12730351 ! lamellipodium assembly GO:0030032 20 11 0,000 0,08291131 0,12722232 ! regulation of embryonic development GO:0045995 27 11 0,000 0,08291131 0,12714124 ! nucleus localization GO:0051647 19 11 0,000 0,08291131 0,12706026 ! regulation of synapse organization GO:0050807 17 11 0,000 0,08291131 0,12697938 ! ear development GO:0043583 103 62 1,000 0,08517093 0,13035704 ! regulation of mitosis GO:0007088 105 63 1,000 0,08752546 0,13387556 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,08752546 0,1337905 ! detection of external stimulus GO:0009581 91 63 1,000 0,08752546 0,13370556 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,08989933 0,13724479 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,09010034 0,13746443 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,09010034 0,13737732 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,09010034 0,13729032 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,09010034 0,13720342 ! virus-host interaction GO:0019048 29 12 0,000 0,09010034 0,13711664 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,09010034 0,13702997 ! cartilage condensation GO:0001502 20 12 0,000 0,09010034 0,13694341 ! mating GO:0007618 17 12 0,000 0,09010034 0,13685695 ! protein complex disassembly GO:0043241 27 12 0,000 0,09010034 0,13677061 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,09010034 0,13668437 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,09010034 0,13659824 ! hippocampus development GO:0021766 26 12 0,000 0,09010034 0,13651222 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,09010034 0,13642631 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,09010034 0,13634051 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,09010034 0,13625482 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,09010034 0,13616923 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,09010034 0,13608375 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,09010034 0,13599838 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,09010034 0,13591311 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,09010034 0,13582795 ! drug transport GO:0015893 16 12 0,000 0,09010034 0,1357429 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,09010034 0,13565795 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,09010034 0,13557312 ! polyamine metabolic process GO:0006595 17 12 0,000 0,09010034 0,13548838 ! mitotic spindle organization GO:0007052 21 12 0,000 0,09010034 0,13540375 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,09010034 0,13531923 ! asymmetric protein localization GO:0008105 20 12 0,000 0,09010034 0,13523482 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,09010034 0,13515051 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,09010034 0,1350663 ! entry into host cell GO:0030260 32 12 0,000 0,09010034 0,1349822 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,09010034 0,1348982 ! monoamine transport GO:0015844 18 12 0,000 0,09010034 0,13481431 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,09010034 0,13473052 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,09010034 0,13464684 GO:0015800|acidic amino acid transport, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,09010034 0,13456326 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,09010034 0,13447978 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,09010034 0,13439641 ! protein homotetramerization GO:0051289 21 12 0,000 0,09010034 0,13431314 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,09010034 0,13422998 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,09010034 0,13414691 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,09010034 0,13406395 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,09010034 0,13398109 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,09010034 0,13389834 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,09010034 0,13381569 ! fucose catabolic process GO:0019317 22 12 0,000 0,09010034 0,13373313 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,09010034 0,13365069 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,09010034 0,13356834 ! T cell homeostasis GO:0043029 25 12 0,000 0,09010034 0,13348609 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,09010034 0,13340395 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,09010034 0,1333219 ! spleen development GO:0048536 22 12 0,000 0,09010034 0,13323996 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,09010034 0,13315811 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,09010034 0,13307637 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,09010034 0,13299473 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,09010034 0,13291319 ! response to cold GO:0009409 17 12 0,000 0,09010034 0,13283175 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,09010034 0,1327504 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,09010034 0,13266916 ! actin filament organization GO:0007015 148 66 1,000 0,09470335 0,13936163 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,09713263 0,14284908 ! activation of MAPK activity GO:0000187 115 67 1,000 0,09713263 0,14276182 ! cGMP metabolic process GO:0046068 18 13 0,000 0,09723325 0,14282247 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,09723325 0,14273533 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,09723325 0,14264829 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,09723325 0,14256136 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,09723325 0,14247454 ! lipid localization GO:0010876 28 13 0,000 0,09723325 0,14238783 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,09723325 0,14230122 ! organelle fusion GO:0048284 32 13 0,000 0,09723325 0,14221471 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,09723325 0,14212831 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,09723325 0,14204201 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,09723325 0,14195582 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,09723325 0,14186974 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,09723325 0,14178376 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,09723325 0,14169788 ! methionine metabolic process GO:0006555 27 13 0,000 0,09723325 0,14161211 ! plasma membrane organization GO:0007009 24 13 0,000 0,09723325 0,14152644 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,09723325 0,14144087 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,09723325 0,14135541 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,09723325 0,14127005 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,09723325 0,14118479 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,09723325 0,14109964 ! response to X-ray GO:0010165 25 13 0,000 0,09723325 0,14101459 ! cytokine metabolic process GO:0042107 22 13 0,000 0,09723325 0,14092964 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,09723325 0,14084479 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,09723325 0,14076005 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,09723325 0,1406754 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,09723325 0,14059086 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,09723325 0,14050643 ! regulation of DNA repair GO:0006282 21 13 0,000 0,09723325 0,14042209 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,09723325 0,14033785 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,09723325 0,14025372 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,09723325 0,14016968 ! regulation of cellular pH GO:0030641 22 13 0,000 0,09723325 0,14008575 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,09723325 0,14000191 ! ribosome assembly GO:0042255 17 13 0,000 0,09723325 0,13991818 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,09723325 0,13983455 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,09723325 0,13975101 ! regulation of epidermis development GO:0045682 19 13 0,000 0,09723325 0,13966758 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,09723325 0,13958425 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,09723325 0,13950101 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,09723325 0,13941788 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,09723325 0,13933484 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,09723325 0,1392519 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,09723325 0,13916906 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,09723325 0,13908632 ! insulin secretion GO:0030073 23 13 0,000 0,09723325 0,13900368 ! actin filament polymerization GO:0030041 24 13 0,000 0,09723325 0,13892114 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,09723325 0,13883869 ! acrosome reaction GO:0007340 18 13 0,000 0,09723325 0,13875635 ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,0995795 0,14202032 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! rRNA transcription GO:0009303 25 14 0,000 0,10431048 0,14867951 ! lactation GO:0007595 26 14 0,000 0,10431048 0,14859148 ! reproductive cellular process GO:0048610 20 14 0,000 0,10431048 0,14850356 ! tRNA modification GO:0006400 20 14 0,000 0,10431048 0,14841574 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,10431048 0,14832802 ! regulation of S phase GO:0033261 23 14 0,000 0,10431048 0,14824041 ! water transport GO:0006833 21 14 0,000 0,10431048 0,1481529 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,10431048 0,1480655 ! non-recombinational repair GO:0000726 25 14 0,000 0,10431048 0,14797819 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,10431048 0,14789099 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,10431048 0,1478039 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,10431048 0,1477169 ! RNA polyadenylation GO:0043631 30 14 0,000 0,10431048 0,14763001 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,10431048 0,14754322 ! palate development GO:0060021 31 14 0,000 0,10431048 0,14745653 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,10431048 0,14736994 ! regulated secretory pathway GO:0045055 23 14 0,000 0,10431048 0,14728346 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,10431048 0,14719708 ! arginine metabolic process GO:0006525 17 14 0,000 0,10431048 0,14711079 ! regulation of heart rate GO:0002027 24 14 0,000 0,10431048 0,14702461 ! organic alcohol transport GO:0015850 29 14 0,000 0,10431048 0,14693853 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,10431048 0,14685255 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,10431048 0,14676668 ! neutral amino acid transport GO:0015804 26 14 0,000 0,10431048 0,1466809 ! L-amino acid transport GO:0015807 30 14 0,000 0,10431048 0,14659522 ! bone mineralization GO:0030282 17 14 0,000 0,10431048 0,14650964 ! stem cell development GO:0048864 43 14 0,000 0,10431048 0,14642416 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,10431048 0,14633878 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,10431048 0,14625351 ! cerebellum development GO:0021549 21 14 0,000 0,10431048 0,14616833 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,10431048 0,14608325 ! response to gamma radiation GO:0010332 28 14 0,000 0,10431048 0,14599826 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,10431048 0,14591338 ! cofactor transport GO:0051181 26 14 0,000 0,10431048 0,1458286 ! NADP metabolic process GO:0006739 24 14 0,000 0,10431048 0,14574391 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,10431048 0,14565932 ! intestinal absorption GO:0050892 25 14 0,000 0,10431048 0,14557483 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,10431048 0,14549044 ! oxygen transport GO:0015671 21 14 0,000 0,10431048 0,14540615 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,10431048 0,14532195 ! male genitalia development GO:0030539 24 14 0,000 0,10431048 0,14523786 ! regulation of axon extension GO:0030516 37 14 0,000 0,10431048 0,14515385 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,10431048 0,14506995 ! acute inflammatory response GO:0002526 113 72 1,000 0,10953469 0,15224753 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,10953469 0,15215962 ! carbohydrate transport GO:0008643 110 72 1,000 0,10953469 0,15207182 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,11133246 0,15447861 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,11133246 0,15438957 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,11133246 0,15430064 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,11133246 0,1542118 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,11133246 0,15412307 ! copper ion transport GO:0006825 20 15 0,000 0,11133246 0,15403445 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,11133246 0,15394592 ! sulfate transport GO:0008272 23 15 0,000 0,11133246 0,1538575 ! response to cAMP GO:0051591 22 15 0,000 0,11133246 0,15376918 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,11133246 0,15368095 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,11133246 0,15359283 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,11133246 0,15350482 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,11133246 0,1534169 ! response to hexose stimulus GO:0009746 22 15 0,000 0,11133246 0,15332908 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,11133246 0,15324136 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,11133246 0,15315375 ! vesicle coating GO:0006901 33 15 0,000 0,11133246 0,15306623 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,11133246 0,15297881 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,11133246 0,1528915 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,11133246 0,15280428 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,11133246 0,15271716 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,11133246 0,15263014 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,11133246 0,15254323 ! regulation of vasodilation GO:0042312 26 15 0,000 0,11133246 0,15245641 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,11133246 0,15236968 ! mRNA splice site selection GO:0006376 38 15 0,000 0,11133246 0,15228306 ! tissue regeneration GO:0042246 26 15 0,000 0,11133246 0,15219654 ! water homeostasis GO:0030104 27 15 0,000 0,11133246 0,15211011 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,11133246 0,15202378 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,11133246 0,15193755 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,11133246 0,15185142 ! heme biosynthetic process GO:0006783 29 15 0,000 0,11133246 0,15176538 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,11133246 0,15167945 ! detection of bacterium GO:0016045 18 15 0,000 0,11133246 0,15159361 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,11133246 0,15150786 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,11133246 0,15142222 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,11133246 0,15133667 ! peptide hormone processing GO:0016486 23 15 0,000 0,11133246 0,15125122 ! learning or memory GO:0007611 147 73 1,000 0,11206337 0,15215827 ! axon guidance GO:0007411 139 73 1,000 0,11206337 0,15207245 ! meiosis GO:0007126 121 74 1,000 0,11460719 0,15543681 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 1,000 0,11460719 0,15534924 ! eye development GO:0001654 143 74 1,000 0,11460719 0,15526177 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,11716578 0,15863864 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,11716578 0,15854942 ! meiotic cell cycle GO:0051321 122 75 1,000 0,11716578 0,15846029 ! rhythmic process GO:0048511 128 75 1,000 0,11716578 0,15837127 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,11829963 0,15981409 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,11829963 0,15972441 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,11829963 0,15963483 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,11829963 0,15954535 ! bone remodeling GO:0046849 27 16 0,000 0,11829963 0,15945597 ! filopodium assembly GO:0046847 32 16 0,000 0,11829963 0,15936668 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,11829963 0,1592775 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,11829963 0,15918842 ! startle response GO:0001964 28 16 0,000 0,11829963 0,15909944 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,11829963 0,15901056 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,11829963 0,15892177 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,11829963 0,15883309 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,11829963 0,15874451 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,11829963 0,15865602 ! protein polyubiquitination GO:0000209 34 16 0,000 0,11829963 0,15856763 ! glutamate metabolic process GO:0006536 22 16 0,000 0,11829963 0,15847934 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,11829963 0,15839115 ! response to osmotic stress GO:0006970 25 16 0,000 0,11829963 0,15830306 ! lysosomal transport GO:0007041 26 16 0,000 0,11829963 0,15821506 ! fructose metabolic process GO:0006000 25 16 0,000 0,11829963 0,15812717 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,11829963 0,15803937 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,11829963 0,15795166 ! intermediate filament-based process GO:0045103 32 16 0,000 0,11829963 0,15786406 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,11829963 0,15777655 ! negative regulation of immune response GO:0050777 35 16 0,000 0,11829963 0,15768914 ! axon cargo transport GO:0008088 43 16 0,000 0,11829963 0,15760183 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,11829963 0,15751461 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,11829963 0,15742749 ! neuron recognition GO:0008038 35 16 0,000 0,11829963 0,15734046 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,11829963 0,15725353 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,11829963 0,1571667 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,11829963 0,15707997 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,11829963 0,15699332 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,11829963 0,15690678 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,11829963 0,15682033 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,11829963 0,15673397 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,11829963 0,15664771 ! blood coagulation GO:0007596 146 78 1,000 0,12492629 0,16533149 GO:0050817|coagulation, ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,12492629 0,1652406 ! response to steroid hormone stimulus GO:0048545 137 78 1,000 0,12492629 0,16514981 ! protein oligomerization GO:0051259 139 78 1,000 0,12492629 0,16505912 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,1252124 0,16534634 ! metencephalon development GO:0022037 30 17 0,000 0,1252124 0,16525563 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,1252124 0,16516503 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,1252124 0,16507453 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,1252124 0,16498413 ! signal complex assembly GO:0007172 41 17 0,000 0,1252124 0,16489383 ! endothelial cell migration GO:0043542 28 17 0,000 0,1252124 0,16480362 ! inositol metabolic process GO:0006020 28 17 0,000 0,1252124 0,16471352 ! gene silencing by RNA GO:0031047 36 17 0,000 0,1252124 0,16462351 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,1252124 0,1645336 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,1252124 0,16444379 ! adult walking behavior GO:0007628 33 17 0,000 0,1252124 0,16435408 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,1252124 0,16426446 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,1252124 0,16417494 ! myoblast differentiation GO:0045445 45 17 0,000 0,1252124 0,16408552 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,1252124 0,1639962 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,1252124 0,16390698 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,1252124 0,16381785 ! NAD metabolic process GO:0019674 29 17 0,000 0,1252124 0,16372882 ! membrane budding GO:0006900 37 17 0,000 0,1252124 0,16363988 ! DNA integration GO:0015074 29 17 0,000 0,1252124 0,16355104 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,1252124 0,1634623 ! regulation of protein binding GO:0043393 33 17 0,000 0,1252124 0,16337366 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,1252124 0,16328511 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,1252124 0,16319665 ! genitalia development GO:0048806 30 17 0,000 0,1252124 0,1631083 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,1252124 0,16302003 GO:0002712|regulation of B cell mediated immunity, ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,1252124 0,16293187 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,1252124 0,1628438 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,1252124 0,16275582 ! steroid catabolic process GO:0006706 31 17 0,000 0,1252124 0,16266794 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,1252124 0,16258015 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,1252124 0,16249246 ! gas transport GO:0015669 25 17 0,000 0,1252124 0,16240486 ! organic cation transport GO:0015695 31 17 0,000 0,1252124 0,16231736 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,1252124 0,16222995 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,1252124 0,16214264 ! microspike assembly GO:0030035 36 17 0,000 0,1252124 0,16205542 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,1252124 0,16196829 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,12754013 0,16489067 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 1,000 0,12754013 0,16480212 ! muscle cell differentiation GO:0042692 159 80 1,000 0,13016685 0,16810598 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,13016685 0,1680158 ! protein import into nucleus GO:0006606 158 80 1,000 0,13016685 0,16792571 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,13207119 0,17029115 ! neuron maturation GO:0042551 42 18 0,000 0,13207119 0,17019994 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,13207119 0,17010883 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,13207119 0,17001781 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,13207119 0,1699269 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,13207119 0,16983607 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,13207119 0,16974535 ! patterning of blood vessels GO:0001569 39 18 0,000 0,13207119 0,16965472 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,13207119 0,16956419 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,13207119 0,16947376 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,13207119 0,16938342 ! glutamine metabolic process GO:0006541 29 18 0,000 0,13207119 0,16929318 ! response to retinoic acid GO:0032526 26 18 0,000 0,13207119 0,16920303 ! response to fungus GO:0009620 21 18 0,000 0,13207119 0,16911298 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,13207119 0,16902303 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,13207119 0,16893317 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,13207119 0,16884341 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,13207119 0,16875374 ! vitamin transport GO:0051180 27 18 0,000 0,13207119 0,16866417 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,13207119 0,16857469 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,13207119 0,16848531 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,13207119 0,16839602 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,13207119 0,16830683 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,13207119 0,16821773 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,1328061 0,16906428 ! nuclear import GO:0051170 161 81 1,000 0,1328061 0,16897487 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,1328061 0,16888556 ! response to drug GO:0042493 143 82 1,000 0,13545753 0,1721663 ! protein secretion GO:0009306 39 19 0,000 0,13887644 0,17641855 ! negative regulation of defense response GO:0031348 25 19 0,000 0,13887644 0,17632545 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,13887644 0,17623245 ! skin development GO:0043588 36 19 0,000 0,13887644 0,17613955 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,13887644 0,17604675 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,13887644 0,17595404 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,13887644 0,17586143 ! bile acid metabolic process GO:0008206 29 19 0,000 0,13887644 0,17576892 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,13887644 0,17567651 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,13887644 0,1755842 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,13887644 0,17549198 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,13887644 0,17539986 ! heme metabolic process GO:0042168 36 19 0,000 0,13887644 0,17530783 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,13887644 0,1752159 ! plasma membrane fusion GO:0045026 28 19 0,000 0,13887644 0,17512407 ! peptide cross-linking GO:0018149 37 19 0,000 0,13887644 0,17503233 ! protein export from nucleus GO:0006611 36 19 0,000 0,13887644 0,17494069 ! heart process GO:0003015 30 19 0,000 0,13887644 0,17484915 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,13887644 0,1747577 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,13887644 0,17466635 ! visual learning GO:0008542 36 19 0,000 0,13887644 0,17457509 ! cellular pigmentation GO:0033059 36 19 0,000 0,13887644 0,17448393 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,13887644 0,17439286 ! cell-cell junction organization GO:0045216 35 19 0,000 0,13887644 0,17430189 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,13887644 0,17421101 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,13887644 0,17412023 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,13887644 0,17402954 ! cilium assembly GO:0042384 37 19 0,000 0,13887644 0,17393895 ! hemostasis GO:0007599 158 84 1,000 0,14079549 0,17625076 ! regulation of ligase activity GO:0051340 142 84 1,000 0,14079549 0,1761591 ! response to unfolded protein GO:0006986 131 85 1,000 0,14348135 0,17942626 ! nucleosome assembly GO:0006334 122 85 1,000 0,14348135 0,17933305 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,14562856 0,18192228 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,14562856 0,18182787 ! positive regulation of ossification GO:0045778 47 20 0,000 0,14562856 0,18173357 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,14562856 0,18163935 ! cAMP metabolic process GO:0046058 36 20 0,000 0,14562856 0,18154524 ! response to vitamin GO:0033273 31 20 0,000 0,14562856 0,18145122 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,14562856 0,18135731 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,14562856 0,18126348 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,14562856 0,18116976 ! retinoid metabolic process GO:0001523 32 20 0,000 0,14562856 0,18107613 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,14562856 0,1809826 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,14562856 0,18088917 ! cellular response to starvation GO:0009267 33 20 0,000 0,14562856 0,18079583 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,14562856 0,18070259 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,14562856 0,18060944 ! body fluid secretion GO:0007589 31 20 0,000 0,14562856 0,18051639 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,14562856 0,18042344 ! stem cell differentiation GO:0048863 53 20 0,000 0,14562856 0,18033058 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,14562856 0,18023782 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,14562856 0,18014515 ! sensory perception of pain GO:0019233 30 20 0,000 0,14562856 0,18005258 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,14562856 0,1799601 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,14562856 0,17986772 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,14562856 0,17977543 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,14562856 0,17968324 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,14562856 0,17959114 GO:0043450|alkene biosynthetic process, ! regulation of glucose import GO:0046324 29 20 0,000 0,14562856 0,17949914 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,14562856 0,17940723 ! actin filament-based movement GO:0030048 43 20 0,000 0,14562856 0,17931541 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,14562856 0,17922369 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,14562856 0,17913206 ! negative regulation of translation GO:0017148 29 20 0,000 0,14562856 0,17904053 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,14562856 0,17894909 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,14562856 0,17885774 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,15232795 0,18699033 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,15232795 0,18689498 ! glycerol metabolic process GO:0006071 34 21 0,000 0,15232795 0,18679972 ! axis specification GO:0009798 38 21 0,000 0,15232795 0,18670456 ! ovarian follicle development GO:0001541 35 21 0,000 0,15232795 0,1866095 ! smooth muscle contraction GO:0006939 46 21 0,000 0,15232795 0,18651453 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,15232795 0,18641966 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,15232795 0,18632489 ! cell aging GO:0007569 44 21 0,000 0,15232795 0,18623021 ! cytolysis GO:0019835 24 21 0,000 0,15232795 0,18613563 ! vasodilation GO:0042311 39 21 0,000 0,15232795 0,18604114 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,15232795 0,18594676 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,15232795 0,18585246 ! oogenesis GO:0048477 36 21 0,000 0,15232795 0,18575826 ! DNA modification GO:0006304 34 21 0,000 0,15232795 0,18566416 ! collagen fibril organization GO:0030199 59 21 0,000 0,15232795 0,18557015 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,15232795 0,18547624 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,15232795 0,18538243 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,15232795 0,1852887 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,15232795 0,18519508 ! sperm-egg recognition GO:0035036 21 21 0,000 0,15232795 0,18510154 ! ossification GO:0001503 188 90 1,000 0,15706603 0,19076267 ! sex differentiation GO:0007548 145 90 1,000 0,15706603 0,19066643 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,15897504 0,1928865 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,15897504 0,19278928 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,15897504 0,19269216 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,15897504 0,19259513 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,15897504 0,19249821 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,15897504 0,19240138 ! keratinization GO:0031424 28 22 0,000 0,15897504 0,19230464 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,15897504 0,19220801 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,15897504 0,19211147 ! sensory perception of taste GO:0050909 28 22 0,000 0,15897504 0,19201503 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,15897504 0,19191868 ! vacuolar transport GO:0007034 36 22 0,000 0,15897504 0,19182244 ! lysosome organization GO:0007040 41 22 0,000 0,15897504 0,19172628 ! central nervous system neuron development GO:0021954 46 22 0,000 0,15897504 0,19163023 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,15897504 0,19153427 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,15897504 0,19143841 ! fucose metabolic process GO:0006004 39 22 0,000 0,15897504 0,19134264 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,15897504 0,19124697 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,15897504 0,19115139 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,15897504 0,19105591 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,15897504 0,19096053 ! sarcomere organization GO:0045214 30 22 0,000 0,15897504 0,19086524 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,15897504 0,19077004 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,15897504 0,19067494 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,15897504 0,19057994 ! protein stabilization GO:0050821 39 22 0,000 0,15897504 0,19048503 ! bone development GO:0060348 189 91 1,000 0,15981178 0,1913923 ! response to protein stimulus GO:0051789 149 91 1,000 0,15981178 0,19129708 ! nucleosome organization GO:0034728 138 92 1,000 0,1625664 0,19449765 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,16557021 0,19799301 ! gluconeogenesis GO:0006094 33 23 0,000 0,16557021 0,19789465 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,16557021 0,19779639 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,16557021 0,19769823 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,16557021 0,19760017 GO:0006044|N-acetylglucosamine metabolic process, ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,16557021 0,1975022 ! visual behavior GO:0007632 42 23 0,000 0,16557021 0,19740433 ! response to ethanol GO:0045471 46 23 0,000 0,16557021 0,19730656 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,16557021 0,19720888 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,16557021 0,1971113 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,16557021 0,19701382 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,16557021 0,19691643 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,16557021 0,19681914 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,16557021 0,19672194 GO:0051693|actin filament capping, ! sex determination GO:0007530 47 23 0,000 0,16557021 0,19662484 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,16557021 0,19652784 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,16557021 0,19643093 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,16557021 0,19633412 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,16557021 0,19623741 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,16557021 0,19614079 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,16557021 0,19604426 ! fatty acid transport GO:0015908 44 23 0,000 0,16557021 0,19594783 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,16557021 0,19585149 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,16557021 0,19575525 ! cell-cell recognition GO:0009988 25 23 0,000 0,16557021 0,1956591 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,16557021 0,19556305 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,16557021 0,19546709 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,16557021 0,19537123 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,16557021 0,19527546 GO:0006099|tricarboxylic acid cycle, ! biogenic amine metabolic process GO:0006576 155 94 1,000 0,16810105 0,19816322 ! female pregnancy GO:0007565 164 94 1,000 0,16810105 0,19806617 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,17211389 0,20269507 ! vesicle docking GO:0048278 47 24 0,000 0,17211389 0,2025959 ! vacuole organization GO:0007033 43 24 0,000 0,17211389 0,20249683 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,17211389 0,20239786 ! digestive system process GO:0022600 39 24 0,000 0,17211389 0,20229899 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,17211389 0,20220021 ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,17211389 0,20210152 ! membrane depolarization GO:0051899 39 24 0,000 0,17211389 0,20200294 ! pentose metabolic process GO:0019321 35 24 0,000 0,17211389 0,20190445 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,17211389 0,20180605 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,17211389 0,20170776 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,17211389 0,20160955 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,17211389 0,20151145 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,17211389 0,20141344 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,17211389 0,20131552 ! protein tetramerization GO:0051262 52 24 0,000 0,17211389 0,2012177 ! positive regulation of immune response GO:0050778 156 96 1,000 0,17366757 0,20293549 ! protein ubiquitination GO:0016567 217 97 1,000 0,17646206 0,20610083 ! hormone metabolic process GO:0042445 157 97 1,000 0,17646206 0,20600083 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,17860647 0,20840309 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,17860647 0,20830207 ! phototransduction GO:0007602 33 25 0,000 0,17860647 0,20820115 ! sperm motility GO:0030317 31 25 0,000 0,17860647 0,20810032 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,17860647 0,2079996 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,17860647 0,20789897 ! receptor metabolic process GO:0043112 46 25 0,000 0,17860647 0,20779844 ! chromosome condensation GO:0030261 45 25 0,000 0,17860647 0,207698 ! response to starvation GO:0042594 42 25 0,000 0,17860647 0,20759766 ! osteoblast differentiation GO:0001649 60 25 0,000 0,17860647 0,20749742 ! coenzyme catabolic process GO:0009109 39 25 0,000 0,17860647 0,20739728 ! negative regulation of cell development GO:0010721 73 25 0,000 0,17860647 0,20729723 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,17860647 0,20719728 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,17860647 0,20709743 ! interaction with host GO:0051701 62 25 0,000 0,17860647 0,20699767 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,17860647 0,20689801 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,17860647 0,20679844 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,17860647 0,20669897 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,17860647 0,2065996 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,17860647 0,20650032 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,17860647 0,20640114 ! telomere organization GO:0032200 43 25 0,000 0,17860647 0,20630205 GO:0000723|telomere maintenance, ! liver development GO:0001889 53 25 0,000 0,17860647 0,20620305 ! carboxylic acid catabolic process GO:0046395 156 98 1,000 0,17926364 0,2068625 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 1,000 0,18207204 0,21000255 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,18504834 0,21333316 ! embryonic pattern specification GO:0009880 44 26 0,000 0,18504834 0,21323099 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,18504834 0,21312892 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,18504834 0,21302694 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,18504834 0,21292507 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,18504834 0,21282329 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,18504834 0,2127216 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,18504834 0,21262002 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,18504834 0,21251853 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,18504834 0,21241713 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,18504834 0,21231584 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,18504834 0,21221464 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,18504834 0,21211354 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,18504834 0,21201253 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,18504834 0,21191162 ! blastocyst development GO:0001824 49 26 0,000 0,18504834 0,21181081 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,18504834 0,21171009 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,18504834 0,21160946 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,19143991 0,21881445 ! iron ion transport GO:0006826 59 27 0,000 0,19143991 0,21871055 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,19143991 0,21860675 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,19143991 0,21850304 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,19143991 0,21839944 ! fat cell differentiation GO:0045444 50 27 0,000 0,19143991 0,21829593 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,19143991 0,21819252 ! autophagy GO:0006914 41 27 0,000 0,19143991 0,21808921 ! male gonad development GO:0008584 44 27 0,000 0,19143991 0,217986 ! response to toxin GO:0009636 47 27 0,000 0,19143991 0,21788288 ! base-excision repair GO:0006284 41 27 0,000 0,19143991 0,21777987 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,19143991 0,21767695 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,19143991 0,21757412 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,19143991 0,2174714 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,19143991 0,21736877 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,19143991 0,21726624 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,19778156 0,22435758 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,19778156 0,22425185 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,19778156 0,22414622 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,19778156 0,22404069 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,19778156 0,22393526 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,19778156 0,22382993 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,19778156 0,22372469 ! synaptogenesis GO:0007416 42 28 0,000 0,19778156 0,22361956 ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,19778156 0,22351452 ! translational initiation GO:0006413 65 29 0,000 0,20407367 0,23051702 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,20407367 0,23040885 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,20407367 0,23030078 ! regulation of pH GO:0006885 43 29 0,000 0,20407367 0,23019281 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,20407367 0,23008494 ! complement activation, classical pathway GO:0006958 48 29 0,000 0,20407367 0,22997717 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,20407367 0,2298695 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,20407367 0,22976194 GO:0002764|immune response-regulating signal transduction, ! cell fate determination GO:0001709 60 29 0,000 0,20407367 0,22965447 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,20407367 0,22954711 ! detection of light stimulus GO:0009583 38 29 0,000 0,20407367 0,22943984 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,20407367 0,22933268 ! regulation of coagulation GO:0050818 46 29 0,000 0,20407367 0,22922561 ! zinc ion transport GO:0006829 45 30 0,000 0,21031665 0,23612779 ! membrane docking GO:0022406 61 30 0,000 0,21031665 0,23601766 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,21031665 0,23590763 ! myofibril assembly GO:0030239 47 30 0,000 0,21031665 0,2357977 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,21031665 0,23568787 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,21031665 0,23557815 ! phospholipid transport GO:0015914 51 30 0,000 0,21031665 0,23546852 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,21031665 0,235359 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,21031665 0,23524958 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,21651086 0,24206558 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,21651086 0,24195315 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,21651086 0,24184082 GO:0009799|determination of symmetry, ! inner ear morphogenesis GO:0042472 47 31 0,000 0,21651086 0,2417286 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,21651086 0,24161648 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,21651086 0,24150447 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,21651086 0,24139255 ! ovulation cycle process GO:0022602 49 31 0,000 0,21651086 0,24128075 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,21651086 0,24116904 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,21651086 0,24105744 ! mesoderm formation GO:0001707 69 31 0,000 0,21651086 0,24094594 ! natural killer cell activation GO:0030101 45 31 0,000 0,21651086 0,24083455 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,21651086 0,24072326 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,22265669 0,24744203 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,22265669 0,24732779 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,22265669 0,24721366 ! cholesterol transport GO:0030301 56 32 0,000 0,22265669 0,24709963 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,22265669 0,24698571 ! spliceosome assembly GO:0000245 67 32 0,000 0,22265669 0,24687189 ! spindle organization GO:0007051 46 32 0,000 0,22265669 0,24675818 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,22265669 0,24664457 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,22265669 0,24653106 ! muscle cell development GO:0055001 49 32 0,000 0,22265669 0,24641766 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,22265669 0,24630437 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,22265669 0,24619118 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,22265669 0,24607809 ! ovulation cycle GO:0042698 51 32 0,000 0,22265669 0,2459651 ! BMP signaling pathway GO:0030509 64 32 0,000 0,22265669 0,24585223 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,22265669 0,24573945 ! post-embryonic development GO:0009791 69 33 0,000 0,22875451 0,25235367 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,22875451 0,25223802 ! ceramide metabolic process GO:0006672 64 33 0,000 0,22875451 0,25212247 ! formation of primary germ layer GO:0001704 72 33 0,000 0,22875451 0,25200703 ! sterol transport GO:0015918 57 33 0,000 0,22875451 0,2518917 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,22875451 0,25177647 ! adult locomotory behavior GO:0008344 59 33 0,000 0,22875451 0,25166135 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,22875451 0,25154633 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,23480471 0,25808137 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,23480471 0,25796353 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,23480471 0,25784579 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,23480471 0,25772816 ! spermatid development GO:0007286 63 34 0,000 0,23480471 0,25761063 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,23480471 0,25749322 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,23480471 0,25737591 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,23480471 0,25725871 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,24080763 0,2637156 ! female gonad development GO:0008585 58 35 0,000 0,24080763 0,26359562 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,24080763 0,26347575 GO:0006639|acylglycerol metabolic process, ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,24080763 0,26335598 ! cytokine production GO:0001816 59 35 0,000 0,24080763 0,26323633 ! vesicle localization GO:0051648 64 35 0,000 0,24080763 0,26311679 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,24676367 0,26950222 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,24676367 0,26937994 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,24676367 0,26925777 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,24676367 0,26913571 ! positive regulation of cell development GO:0010720 80 36 0,000 0,24676367 0,26901377 ! regulation of proteolysis GO:0030162 72 36 0,000 0,24676367 0,26889193 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,24676367 0,2687702 ! aerobic respiration GO:0009060 55 36 0,000 0,24676367 0,26864859 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,24676367 0,26852708 ! RNA export from nucleus GO:0006405 56 37 0,000 0,25267317 0,27483348 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,25267317 0,27470929 ! meiosis I GO:0007127 65 37 0,000 0,25267317 0,27458521 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,25267317 0,27446124 ! sister chromatid segregation GO:0000819 58 37 0,000 0,25267317 0,27433739 ! actomyosin structure organization GO:0031032 62 37 0,000 0,25267317 0,27421364 ! organic anion transport GO:0015711 68 37 0,000 0,25267317 0,27409001 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,25267317 0,27396649 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,25267317 0,27384308 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,25267317 0,27371979 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,25267317 0,2735966 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,25267317 0,27347353 ! spermatid differentiation GO:0048515 66 37 0,000 0,25267317 0,27335056 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,25853651 0,27956801 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,25853651 0,27944242 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,25853651 0,27931694 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,25853651 0,27919158 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 67 38 0,000 0,25853651 0,27906632 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,25853651 0,27894118 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,25853651 0,27881615 ! mRNA catabolic process GO:0006402 71 39 0,000 0,26435403 0,28496228 ! learning GO:0007612 77 39 0,000 0,26435403 0,28483466 ! organic ether metabolic process GO:0018904 55 39 0,000 0,26435403 0,28470716 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,26435403 0,28457978 ! ion transmembrane transport GO:0034220 66 39 0,000 0,26435403 0,28445251 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,26435403 0,28432535 ! RNA modification GO:0009451 57 39 0,000 0,26435403 0,2841983 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,26435403 0,28407137 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,27012611 0,29014438 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,27012611 0,29001491 ! cytokinesis GO:0000910 72 40 0,000 0,27012611 0,28988555 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,27585308 0,29589947 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,27585308 0,29576761 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,27585308 0,29563586 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,27585308 0,29550424 ! T cell differentiation GO:0030217 81 41 0,000 0,27585308 0,29537273 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,27585308 0,29524133 ! female gamete generation GO:0007292 61 41 0,000 0,27585308 0,29511006 ! polyol metabolic process GO:0019751 66 41 0,000 0,27585308 0,2949789 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,28153531 0,30092135 ! regulation of tube size GO:0035150 71 42 0,000 0,28153531 0,30078772 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,28153531 0,30065422 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,28153531 0,30052083 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,28153531 0,30038756 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,28717314 0,3062671 ! striated muscle contraction GO:0006941 77 43 0,000 0,28717314 0,3061314 ! phagocytosis GO:0006909 90 43 0,000 0,28717314 0,30599582 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,28717314 0,30586037 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,29276691 0,31168017 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,29276691 0,31154232 ! male sex differentiation GO:0046661 76 44 0,000 0,29276691 0,31140459 ! double-strand break repair GO:0006302 81 44 0,000 0,29276691 0,31126698 ! B cell differentiation GO:0030183 107 44 0,000 0,29276691 0,3111295 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,29831697 0,3168877 ! glycolysis GO:0006096 65 45 0,000 0,29831697 0,31674785 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,29831697 0,31660813 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,29831697 0,31646853 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,29831697 0,31632906 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,29831697 0,31618971 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,30382366 0,32188451 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,30382366 0,32174284 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,30382366 0,32160129 ! endosome transport GO:0016197 108 47 0,000 0,30928732 0,32724067 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,30928732 0,32709683 ! JNK cascade GO:0007254 91 47 0,000 0,30928732 0,32695312 ! mitochondrial transport GO:0006839 82 48 0,000 0,31470828 0,3325376 ! Notch signaling pathway GO:0007219 96 48 0,000 0,31470828 0,33239162 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,31470828 0,33224577 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,31470828 0,33210005 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,32008687 0,3376278 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,32008687 0,33747984 ! regulation of ion transport GO:0043269 77 49 0,000 0,32008687 0,33733202 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,32008687 0,33718433 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,32008687 0,33703676 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,32008687 0,33688933 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,32008687 0,33674202 ! neuromuscular process GO:0050905 99 50 0,000 0,32542342 0,34220662 ! inner ear development GO:0048839 79 50 0,000 0,32542342 0,34205712 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,33071827 0,34747081 ! excretion GO:0007588 83 51 0,000 0,33071827 0,34731914 ! vesicle organization GO:0016050 107 51 0,000 0,33071827 0,3471676 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,33597172 0,35252855 ! membrane fusion GO:0006944 110 52 0,000 0,33597172 0,35237488 ! amino acid activation GO:0043038 92 52 0,000 0,33597172 0,35222134 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,34118412 0,35753005 ! RNA catabolic process GO:0006401 93 53 0,000 0,34118412 0,3573744 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,34118412 0,35721888 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,34118412 0,3570635 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,34118412 0,35690826 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,34118412 0,35675315 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,34118412 0,35659817 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,34635577 0,36184628 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,34635577 0,36168923 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,34635577 0,36153232 ! chloride transport GO:0006821 90 55 0,000 0,351487 0,36672928 ! glucose catabolic process GO:0006007 82 55 0,000 0,351487 0,36657031 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,351487 0,36641149 ! gastrulation GO:0007369 112 55 0,000 0,351487 0,3662528 ! nuclear export GO:0051168 97 55 0,000 0,351487 0,36609425 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,351487 0,36593584 ! regulation of actin filament length GO:0030832 105 56 0,000 0,35657811 0,37107566 ! sensory perception of smell GO:0007608 80 56 0,000 0,35657811 0,37091523 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,35657811 0,37075494 ! proton transport GO:0015992 94 56 0,000 0,35657811 0,37059479 ! hydrogen transport GO:0006818 97 58 0,000 0,36664125 0,38088897 ! regulation of endocytosis GO:0030100 91 58 0,000 0,36664125 0,38072458 ! regulation of cellular component size GO:0032535 109 59 0,000 0,37161389 0,38572175 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,37161389 0,38555542 GO:0032313|regulation of Rab GTPase activity, ! establishment of organelle localization GO:0051656 109 59 0,000 0,37161389 0,38538924 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,37654766 0,39033764 ! regulation of heart contraction GO:0008016 110 60 0,000 0,37654766 0,39016954 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,37654766 0,39000158 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,38144285 0,39490168 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,38144285 0,39473183 ! mesoderm development GO:0007498 119 61 0,000 0,38144285 0,39456212 ! tRNA processing GO:0008033 89 61 0,000 0,38144285 0,39439256 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,38144285 0,39422315 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,38629977 0,39907138 ! gonad development GO:0008406 98 62 0,000 0,38629977 0,3989001 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,39111871 0,40370296 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,39111871 0,40352985 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,39589997 0,40828775 ! cell redox homeostasis GO:0045454 102 64 0,000 0,39589997 0,40811282 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,39589997 0,40793804 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,39589997 0,40776341 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,40064384 0,41247286 ! germ cell development GO:0007281 118 65 0,000 0,40064384 0,41229644 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,40535062 0,41696177 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,40535062 0,41678358 ! extracellular matrix organization GO:0030198 133 66 0,000 0,40535062 0,41660555 ! secondary metabolic process GO:0019748 116 66 0,000 0,40535062 0,41642766 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,41002059 0,42104547 ! chromosome segregation GO:0007059 113 67 0,000 0,41002059 0,42086584 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,41002059 0,42068637 ! hexose catabolic process GO:0019320 104 67 0,000 0,41002059 0,42050705 ! activation of immune response GO:0002253 105 67 0,000 0,41002059 0,42032788 ! amino acid transport GO:0006865 125 68 0,000 0,41465403 0,42489677 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,41465403 0,42471588 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,41465403 0,42453515 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,41465403 0,42435458 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,41925125 0,42887691 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,41925125 0,42869465 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,41925125 0,42851253 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,41925125 0,42833057 ! antigen processing and presentation GO:0019882 104 69 0,000 0,41925125 0,42814877 ! amine catabolic process GO:0009310 117 71 0,000 0,42833809 0,43724287 ! B cell activation GO:0042113 160 71 0,000 0,42833809 0,43705744 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,43282828 0,44145182 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,43282828 0,44126476 ! regulation of blood pressure GO:0008217 125 73 0,000 0,43728335 0,44561785 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,43728335 0,44542919 ! fertilization GO:0009566 90 73 0,000 0,43728335 0,44524068 ! transition metal ion transport GO:0000041 126 74 0,000 0,44170357 0,44955109 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,44170357 0,44936101 ! organelle localization GO:0051640 136 74 0,000 0,44170357 0,44917109 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,44608922 0,45343923 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,45044056 0,45766891 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,45044056 0,45747572 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,45044056 0,45728269 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,45475786 0,46147086 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,45475786 0,46127631 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,45475786 0,46108192 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,4632914 0,46953627 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,4632914 0,46933857 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,46750817 0,47341105 ! inorganic anion transport GO:0015698 138 80 0,000 0,46750817 0,47321188 ! digestion GO:0007586 112 81 0,000 0,47169194 0,47724592 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,47169194 0,47704532 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,47584298 0,48104127 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,47584298 0,48083923 ! response to nutrient GO:0007584 125 82 0,000 0,47584298 0,48063737 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,47584298 0,48043568 ! regulation of lyase activity GO:0051339 160 83 0,000 0,47996155 0,48439072 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,48404788 0,48830994 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,49212489 0,49624999 ! alcohol catabolic process GO:0046164 130 86 0,000 0,49212489 0,49604209 ! amine transport GO:0015837 155 86 0,000 0,49212489 0,49583437 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,49611605 0,49964638 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,49611605 0,49943733 ! cellular respiration GO:0045333 135 88 0,000 0,50007597 0,50321321 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,50007597 0,50300284 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,5079031 0,51066229 ! sterol metabolic process GO:0016125 152 91 0,000 0,51177078 0,51433605 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,51177078 0,5141213 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,51560819 0,51776015 ! vitamin metabolic process GO:0006766 139 92 0,000 0,51560819 0,51754414 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,51941557 0,5211484 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,51941557 0,52093116 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,51941557 0,52071411 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,52694115 0,52803849 ! leukocyte differentiation GO:0002521 202 96 0,000 0,53065982 0,53154352 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,53065982 0,53132232 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,53065982 0,5311013 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,53434938 0,53457156 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,53801006 0,53801006