pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6461-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of intracellular protein transport GO:0033157 25 25 4,000 2,589E-08 4,772E-05 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 4,000 3,914E-08 3,607E-05 ! regulation of intracellular transport GO:0032386 31 31 4,000 8,154E-08 5,009E-05 ! regulation of protein transport GO:0051223 53 53 4,000 1,302E-06 5,999E-04 GO:0070201|regulation of establishment of protein localization, ! regulation of protein localization GO:0032880 58 57 4,000 1,88E-06 6,931E-04 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 2,000 5,651E-06 1,736E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 2,000 7,75E-06 2,04E-03 GO:0032388|positive regulation of intracellular transport, ! activation of MAPKK activity GO:0000186 12 11 2,000 7,75E-06 1,785E-03 ! negative regulation of intracellular transport GO:0032387 13 13 2,000 1,337E-05 2,737E-03 ! regulation of cellular localization GO:0060341 86 85 4,000 1,371E-05 2,527E-03 ! positive regulation of protein kinase activity GO:0045860 89 86 4,000 1,452E-05 2,433E-03 ! positive regulation of transferase activity GO:0051347 91 88 4,000 1,625E-05 2,496E-03 GO:0033674|positive regulation of kinase activity, ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 1,697E-05 2,406E-03 ! regulation of transcription factor import into nucleus GO:0042990 15 15 2,000 2,116E-05 2,785E-03 ! Wnt receptor signaling pathway GO:0016055 46 45 3,000 2,15E-05 2,641E-03 ! regulation of protein import into nucleus GO:0042306 21 21 2,000 6,092E-05 7,017E-03 ! negative regulation of protein transport GO:0051224 21 21 2,000 6,092E-05 6,605E-03 ! spindle organization GO:0007051 22 22 2,000 7,036E-05 7,205E-03 ! androgen receptor signaling pathway GO:0030521 24 24 2,000 9,202E-05 8,926E-03 ! learning or memory GO:0007611 28 27 2,000 1,32E-04 0,01216209 ! memory GO:0007613 5 5 1,000 1,364E-04 0,01196938 ! central nervous system neuron axonogenesis GO:0021955 6 5 1,000 1,364E-04 0,01142532 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 1,364E-04 0,01092857 ! wound healing, spreading of epidermal cells GO:0035313 5 5 1,000 1,364E-04 0,01047321 ! peptidyl-lysine modification GO:0018205 5 5 1,000 1,364E-04 0,01005428 ! nucleus localization GO:0051647 5 5 1,000 1,364E-04 9,668E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 2,000 1,474E-04 0,01006475 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 1,641E-04 0,01079802 ! positive regulation of protein transport GO:0051222 29 29 2,000 1,641E-04 0,01042567 ! cell morphogenesis involved in differentiation GO:0000904 82 77 3,000 1,799E-04 0,01105044 ! axon extension GO:0048675 7 6 1,000 2,041E-04 0,01213416 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 2,041E-04 0,01175497 GO:0018409|peptide or protein amino-terminal blocking, ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 1,000 2,041E-04 0,01139876 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 2,041E-04 0,0110635 ! ER overload response GO:0006983 6 6 1,000 2,041E-04 0,0107474 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 2,041E-04 0,01044886 GO:0070667|negative regulation of mast cell proliferation, ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 2,041E-04 0,01016646 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 2,041E-04 9,899E-03 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 2,041E-04 9,645E-03 ! localization within membrane GO:0051668 6 6 1,000 2,041E-04 9,404E-03 ! activation of protein kinase activity GO:0032147 35 33 2,000 2,425E-04 0,01090103 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 1,000 2,851E-04 0,01250949 ! regulation of mRNA processing GO:0050684 7 7 1,000 2,851E-04 0,01221857 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 2,851E-04 0,01194087 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! negative regulation of T cell activation GO:0050868 7 7 1,000 2,851E-04 0,01167552 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 2,895E-04 0,01159714 ! meiosis GO:0007126 37 37 2,000 3,419E-04 0,0134074 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of protein kinase activity GO:0006469 37 37 2,000 3,419E-04 0,01312808 ! negative regulation of kinase activity GO:0033673 38 38 2,000 3,703E-04 0,0139275 ! meiotic cell cycle GO:0051321 38 38 2,000 3,703E-04 0,01364895 ! steroid hormone receptor signaling pathway GO:0030518 38 38 2,000 3,703E-04 0,01338133 ! zinc ion transport GO:0006829 8 8 1,000 3,792E-04 0,01344045 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 1,000 3,792E-04 0,01318685 ! peptidyl-serine modification GO:0018209 8 8 1,000 3,792E-04 0,01294265 ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 3,792E-04 0,01270733 ! negative regulation of transferase activity GO:0051348 40 40 2,000 4,315E-04 0,01420118 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 2,000 4,315E-04 0,01395204 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 4,864E-04 0,01545693 ! cerebral cortex development GO:0021987 9 9 1,000 4,864E-04 0,01519494 ! central nervous system neuron development GO:0021954 10 9 1,000 4,864E-04 0,0149417 ! negative regulation of protein import into nucleus GO:0042308 9 9 1,000 4,864E-04 0,01469675 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 4,864E-04 0,01445971 ! histone acetylation GO:0016573 9 9 1,000 4,864E-04 0,01423019 ! forebrain development GO:0030900 43 42 2,000 4,989E-04 0,01436615 ! cell-substrate junction assembly GO:0007044 11 10 1,000 6,066E-04 0,01720036 ! central nervous system neuron differentiation GO:0021953 11 10 1,000 6,066E-04 0,01693975 ! neuromuscular junction development GO:0007528 10 10 1,000 6,066E-04 0,01668692 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 6,066E-04 0,01644152 ! phosphoinositide-mediated signaling GO:0048015 45 45 2,000 6,12E-04 0,01634733 ! protein amino acid acetylation GO:0006473 11 11 1,000 7,397E-04 0,0194757 ! dendrite development GO:0016358 11 11 1,000 7,397E-04 0,0192014 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 7,397E-04 0,01893471 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 7,397E-04 0,01867533 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 7,397E-04 0,01842296 ! skeletal muscle tissue development GO:0007519 50 49 2,000 7,867E-04 0,01933231 GO:0060538|skeletal muscle organ development, ! positive regulation of MAP kinase activity GO:0043406 50 49 2,000 7,867E-04 0,01907793 ! negative regulation of transport GO:0051051 51 50 2,000 8,348E-04 0,01998197 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 8,856E-04 0,02092512 ! heterophilic cell adhesion GO:0007157 12 12 1,000 8,856E-04 0,02066025 ! pallium development GO:0021543 13 12 1,000 8,856E-04 0,020402 ! somitogenesis GO:0001756 13 12 1,000 8,856E-04 0,02015012 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 1,044E-03 0,02346875 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 1,044E-03 0,02318599 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 1,044E-03 0,02290997 ! tissue homeostasis GO:0001894 13 13 1,000 1,044E-03 0,02264044 GO:0048871|multicellular organismal homeostasis, ! microtubule cytoskeleton organization GO:0000226 55 55 2,000 1,104E-03 0,02364922 ! protein amino acid acylation GO:0043543 14 14 1,000 1,215E-03 0,02574672 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 1,354E-03 0,0283534 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 1,399E-03 0,02897275 ! negative regulation of cell activation GO:0050866 15 15 1,000 1,399E-03 0,02865083 ! protein homooligomerization GO:0051260 15 15 1,000 1,399E-03 0,02833599 ! axonogenesis GO:0007409 66 62 2,000 1,563E-03 0,03131527 ! segmentation GO:0035282 17 16 1,000 1,595E-03 0,03161402 ! positive regulation of catabolic process GO:0009896 16 16 1,000 1,595E-03 0,0312777 ! angiogenesis GO:0001525 65 64 2,000 1,713E-03 0,03324189 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 1,804E-03 0,03462903 ! myelination GO:0042552 17 17 1,000 1,804E-03 0,03427203 ! leukocyte adhesion GO:0007159 17 17 1,000 1,804E-03 0,03392231 ! glucose transport GO:0015758 17 17 1,000 1,804E-03 0,03357966 ! cell junction assembly GO:0034329 18 17 1,000 1,804E-03 0,03324387 ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 1,804E-03 0,03291472 ! regulation of MAP kinase activity GO:0043405 67 66 2,000 1,873E-03 0,03383454 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 2,000 1,955E-03 0,03498897 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! striated muscle tissue development GO:0014706 69 67 2,000 1,955E-03 0,03465254 ! meiosis I GO:0007127 18 18 1,000 2,025E-03 0,0355358 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 2,025E-03 0,03520056 ! hexose transport GO:0008645 18 18 1,000 2,025E-03 0,03487158 GO:0015749|monosaccharide transport, ! telencephalon development GO:0021537 19 18 1,000 2,025E-03 0,03454869 ! ensheathment of neurons GO:0007272 18 18 1,000 2,025E-03 0,03423173 GO:0008366|axon ensheathment, ! regulation of microtubule-based process GO:0032886 18 18 1,000 2,025E-03 0,03392054 ! positive regulation of transport GO:0051050 71 70 2,000 2,218E-03 0,03682216 ! cell part morphogenesis GO:0032990 75 70 2,000 2,218E-03 0,03649339 ! wound healing GO:0042060 74 70 2,000 2,218E-03 0,03617044 ! muscle tissue development GO:0060537 72 70 2,000 2,218E-03 0,03585316 ! peripheral nervous system development GO:0007422 19 19 1,000 2,257E-03 0,03617877 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 2,76E-03 0,04384302 ! mammary gland development GO:0030879 23 21 1,000 2,76E-03 0,04346829 ! regulation of action potential in neuron GO:0019228 21 21 1,000 2,76E-03 0,04309991 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 3,028E-03 0,04690253 GO:0090047|positive regulation of transcription regulator activity, ! cell junction organization GO:0034330 23 22 1,000 3,028E-03 0,04651167 ! maintenance of protein location in cell GO:0032507 23 22 1,000 3,028E-03 0,04612728 ! neuron migration GO:0001764 22 22 1,000 3,028E-03 0,04574918 ! neuron projection development GO:0031175 85 80 2,000 3,246E-03 0,04864297 ! calcium-mediated signaling GO:0019722 23 23 1,000 3,309E-03 0,04918383 ! cell projection assembly GO:0030031 25 23 1,000 3,309E-03 0,04879036 ! MAPKKK cascade GO:0000165 82 81 2,000 3,363E-03 0,04918801 ! regulation of action potential GO:0001508 24 24 1,000 3,602E-03 0,05226625 ! T cell differentiation GO:0030217 24 24 1,000 3,602E-03 0,05185792 ! maintenance of protein location GO:0045185 25 24 1,000 3,602E-03 0,05145592 ! glucan metabolic process GO:0044042 25 24 1,000 3,602E-03 0,05106011 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! blood vessel morphogenesis GO:0048514 84 83 2,000 3,603E-03 0,05069461 ! endosome transport GO:0016197 25 25 1,000 3,906E-03 0,05453257 ! regulation of T cell proliferation GO:0042129 25 25 1,000 3,906E-03 0,05412255 ! positive regulation of DNA binding GO:0043388 26 25 1,000 3,906E-03 0,05371865 ! negative regulation of immune system process GO:0002683 25 25 1,000 3,906E-03 0,05332074 ! heart development GO:0007507 90 87 2,000 4,116E-03 0,05577141 ! positive regulation of binding GO:0051099 27 26 1,000 4,221E-03 0,05678901 ! glycolysis GO:0006096 26 26 1,000 4,221E-03 0,0563775 ! regulation of T cell differentiation GO:0045580 26 26 1,000 4,221E-03 0,0559719 ! maintenance of location in cell GO:0051651 27 26 1,000 4,221E-03 0,0555721 ! synapse organization GO:0050808 26 26 1,000 4,221E-03 0,05517798 ! brain development GO:0007420 91 90 2,000 4,527E-03 0,0587604 ! energy reserve metabolic process GO:0006112 28 27 1,000 4,549E-03 0,05862268 ! mesenchymal cell development GO:0014031 29 27 1,000 4,549E-03 0,05821557 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! carbohydrate transport GO:0008643 28 28 1,000 4,887E-03 0,06211716 ! histone modification GO:0016570 28 28 1,000 4,887E-03 0,0616917 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 4,887E-03 0,06127203 ! blood vessel development GO:0001568 95 94 2,000 5,114E-03 0,06368756 ! positive regulation of cell cycle GO:0045787 29 29 1,000 5,237E-03 0,06477703 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 5,237E-03 0,06434518 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! covalent chromatin modification GO:0016569 29 29 1,000 5,237E-03 0,06391905 ! response to UV GO:0009411 29 29 1,000 5,237E-03 0,06349853 ! vasculature development GO:0001944 97 96 2,000 5,424E-03 0,06534002 ! transition metal ion transport GO:0000041 31 30 1,000 5,598E-03 0,06699516 ! activation of phospholipase C activity GO:0007202 30 30 1,000 5,598E-03 0,06656293 GO:0010863|positive regulation of phospholipase C activity, ! skeletal muscle fiber development GO:0048741 31 31 1,000 5,97E-03 0,07053376 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 5,97E-03 0,0700845 ! muscle organ development GO:0007517 102 100 2,000 6,078E-03 0,07089468 ! hemopoiesis GO:0030097 104 100 2,000 6,078E-03 0,07044881 ! muscle fiber development GO:0048747 32 32 1,000 6,354E-03 0,07318539 ! glucose catabolic process GO:0006007 32 32 1,000 6,354E-03 0,07273082 ! regulation of phospholipase activity GO:0010517 32 32 1,000 6,354E-03 0,07228187 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 6,354E-03 0,07183842 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 6,354E-03 0,07140038 ! positive regulation of lipase activity GO:0060193 32 32 1,000 6,354E-03 0,07096765 ! maintenance of location GO:0051235 33 32 1,000 6,354E-03 0,07054013 ! regulation of angiogenesis GO:0045765 35 34 1,000 7,153E-03 0,0789401 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 7,153E-03 0,07847022 ! regulation of protein catabolic process GO:0042176 35 34 1,000 7,153E-03 0,0780059 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 7,569E-03 0,08205668 ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 7,996E-03 0,08617576 ! regulation of lipase activity GO:0060191 36 36 1,000 7,996E-03 0,08567473 ! positive regulation of cell migration GO:0030335 36 36 1,000 7,996E-03 0,08517951 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 7,996E-03 0,08468997 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of transcription factor activity GO:0051090 38 37 1,000 8,433E-03 0,08881204 GO:0090046|regulation of transcription regulator activity, ! lung development GO:0030324 38 37 1,000 8,433E-03 0,08830742 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 8,433E-03 0,08780851 ! hexose catabolic process GO:0019320 38 38 1,000 8,881E-03 0,09195305 ! axon guidance GO:0007411 39 38 1,000 8,881E-03 0,09143935 ! respiratory system development GO:0060541 40 39 1,000 9,339E-03 0,0956251 ! lymphocyte differentiation GO:0030098 39 39 1,000 9,339E-03 0,09509678 ! protein oligomerization GO:0051259 39 39 1,000 9,339E-03 0,09457427 ! positive regulation of cell motion GO:0051272 39 39 1,000 9,339E-03 0,09405747 ! respiratory tube development GO:0030323 40 39 1,000 9,339E-03 0,09354629 ! organelle localization GO:0051640 41 40 1,000 9,808E-03 0,09771126 ! regulation of caspase activity GO:0043281 41 41 1,000 0,01028741 0,10193384 ! monosaccharide catabolic process GO:0046365 41 41 1,000 0,01028741 0,10138874 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,01077684 0,10564738 ! protein ubiquitination GO:0016567 43 42 1,000 0,01077684 0,1050884 ! alcohol catabolic process GO:0046164 43 43 1,000 0,01127644 0,10938146 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,01230587 0,11874198 ! regulation of DNA binding GO:0051101 47 45 1,000 0,01230587 0,11812353 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,01283554 0,12256945 ! regulation of membrane potential GO:0042391 46 46 1,000 0,01283554 0,12193765 ! regulation of catabolic process GO:0009894 48 47 1,000 0,01337508 0,12641168 ! leukocyte differentiation GO:0002521 50 49 1,000 0,01448347 0,13618893 ! ossification GO:0001503 50 49 1,000 0,01448347 0,13549762 GO:0060348|bone development, ! gland development GO:0048732 51 49 1,000 0,01448347 0,13481328 ! cell cycle arrest GO:0007050 49 49 1,000 0,01448347 0,13413583 ! T cell activation GO:0042110 51 50 1,000 0,01505216 0,13870566 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,01505216 0,13801558 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,01505216 0,13733233 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,01563042 0,14190573 ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 0,01563042 0,14121012 GO:0051325|interphase, ! response to light stimulus GO:0009416 53 52 1,000 0,01621817 0,14580532 ! response to hypoxia GO:0001666 53 53 1,000 0,01681534 0,15044017 ! carbohydrate catabolic process GO:0016052 53 53 1,000 0,01681534 0,1497134 ! regulation of T cell activation GO:0050863 53 53 1,000 0,01681534 0,14899363 ! response to oxygen levels GO:0070482 55 54 1,000 0,01742186 0,1536291 ! regulation of cell adhesion GO:0030155 56 55 1,000 0,01803764 0,15830178 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,01803764 0,15755153 ! extracellular structure organization GO:0043062 56 56 1,000 0,01866262 0,16224159 ! rRNA transcription GO:0009303 5 5 0,000 0,01875849 0,16230935 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,01875849 0,16155089 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,01875849 0,16079949 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,01875849 0,16005505 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,01875849 0,15931747 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,01875849 0,15858665 ! reproductive cellular process GO:0048610 5 5 0,000 0,01875849 0,15786251 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,01875849 0,15714496 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,01875849 0,15643389 ! prostate gland development GO:0030850 5 5 0,000 0,01875849 0,15572924 ! metencephalon development GO:0022037 5 5 0,000 0,01875849 0,1550309 ! water transport GO:0006833 5 5 0,000 0,01875849 0,1543388 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,01875849 0,15365285 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,01875849 0,15297297 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,01875849 0,15229908 ! glycerol metabolic process GO:0006071 5 5 0,000 0,01875849 0,1516311 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,01875849 0,15096895 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,01875849 0,15031257 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,01875849 0,14966186 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,01875849 0,14901677 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,01875849 0,14837721 ! filopodium assembly GO:0046847 7 5 0,000 0,01875849 0,14774312 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,01875849 0,14711443 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,01875849 0,14649106 ! GTP metabolic process GO:0046039 5 5 0,000 0,01875849 0,14587296 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,01875849 0,14526004 ! mRNA stabilization GO:0048255 5 5 0,000 0,01875849 0,14465226 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,01875849 0,14404954 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,01875849 0,14345183 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,01875849 0,14285905 ! social behavior GO:0035176 5 5 0,000 0,01875849 0,14227115 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,01875849 0,14168808 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,01875849 0,14110976 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,01875849 0,14053614 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,01875849 0,13996717 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,01875849 0,13940278 ! response to lipid GO:0033993 5 5 0,000 0,01875849 0,13884293 ! erythrocyte maturation GO:0043249 5 5 0,000 0,01875849 0,13828756 ! hippocampus development GO:0021766 6 5 0,000 0,01875849 0,13773662 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,01875849 0,13719004 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,01875849 0,13664779 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,01875849 0,13610981 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,01875849 0,13557604 ! mechanosensory behavior GO:0007638 5 5 0,000 0,01875849 0,13504645 ! heart looping GO:0001947 5 5 0,000 0,01875849 0,13452097 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,01875849 0,13399958 ! response to interferon-gamma GO:0034341 5 5 0,000 0,01875849 0,1334822 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,01875849 0,13296881 ! endocrine pancreas development GO:0031018 5 5 0,000 0,01875849 0,13245935 ! pH reduction GO:0045851 5 5 0,000 0,01875849 0,13195378 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,01875849 0,13145206 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,01875849 0,13095413 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,01875849 0,13045996 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,01875849 0,12996951 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,01875849 0,12948274 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,01875849 0,12899959 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,01875849 0,12852004 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,01875849 0,12804404 ! adrenal gland development GO:0030325 5 5 0,000 0,01875849 0,12757155 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,01875849 0,12710254 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,01875849 0,12663696 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,01875849 0,12617478 ! astrocyte differentiation GO:0048708 5 5 0,000 0,01875849 0,12571597 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,01875849 0,12526047 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,01875849 0,12480827 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,01875849 0,12435932 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,01875849 0,12391359 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,01875849 0,12347104 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,01875849 0,12303164 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,01875849 0,12259536 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,01875849 0,12216216 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,01875849 0,12173201 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,01875849 0,12130488 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,01875849 0,12088074 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,01875849 0,12045955 ! sister chromatid cohesion GO:0007062 5 5 0,000 0,01875849 0,12004129 ! response to ATP GO:0033198 5 5 0,000 0,01875849 0,11962592 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,01875849 0,11921342 ! regulation of appetite GO:0032098 5 5 0,000 0,01875849 0,11880375 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,01875849 0,11839689 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,01875849 0,1179928 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,01875849 0,11759146 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,01875849 0,11719285 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01875849 0,11679693 ! receptor clustering GO:0043113 5 5 0,000 0,01875849 0,11640367 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,01875849 0,11601306 ! fear response GO:0042596 5 5 0,000 0,01875849 0,11562505 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,01875849 0,11523964 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,01875849 0,11485678 ! retinol metabolic process GO:0042572 5 5 0,000 0,01875849 0,11447646 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,01875849 0,11409865 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,01875849 0,11372332 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,01875849 0,11335046 ! parturition GO:0007567 5 5 0,000 0,01875849 0,11298003 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01875849 0,11261202 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,01875849 0,1122464 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,01875849 0,11188314 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,01875849 0,11152223 ! protein heterooligomerization GO:0051291 5 5 0,000 0,01875849 0,11116364 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,01875849 0,11080734 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,01875849 0,11045332 ! response to UV-B GO:0010224 5 5 0,000 0,01875849 0,11010156 ! oligodendrocyte development GO:0014003 5 5 0,000 0,01875849 0,10975203 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,01875849 0,10940472 ! activated T cell proliferation GO:0050798 5 5 0,000 0,01875849 0,10905959 ! interaction with symbiont GO:0051702 5 5 0,000 0,01875849 0,10871664 ! cellular extravasation GO:0045123 5 5 0,000 0,01875849 0,10837583 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,01875849 0,10803716 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,01875849 0,10770059 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,01875849 0,10736612 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,01875849 0,10703372 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,01875849 0,10670337 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,01875849 0,10637505 ! response to amine stimulus GO:0014075 5 5 0,000 0,01875849 0,10604874 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,01875849 0,10572444 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,01875849 0,10540211 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,01875849 0,10508173 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,01875849 0,1047633 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,01875849 0,1044468 ! neuron recognition GO:0008038 5 5 0,000 0,01875849 0,1041322 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,01875849 0,10381949 ! decidualization GO:0046697 5 5 0,000 0,01875849 0,10350865 ! hair follicle maturation GO:0048820 5 5 0,000 0,01875849 0,10319967 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,01875849 0,10289253 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,01875849 0,10258721 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,01875849 0,1022837 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,01875849 0,10198198 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,01875849 0,10168203 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,01875849 0,10138384 ! postreplication repair GO:0006301 5 5 0,000 0,01875849 0,1010874 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,01875849 0,10079268 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,01875849 0,10049968 ! histone methylation GO:0016571 5 5 0,000 0,01875849 0,10020838 ! DNA methylation GO:0006306 5 5 0,000 0,01875849 0,09991876 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01875849 0,09963081 ! T cell lineage commitment GO:0002360 5 5 0,000 0,01875849 0,09934451 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,01875849 0,09905986 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,01875849 0,09877683 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,01875849 0,09849541 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,01875849 0,0982156 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,01875849 0,09793737 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,01875849 0,09766071 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,01875849 0,09738561 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,01875849 0,09711205 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,01875849 0,09684003 ! sterol catabolic process GO:0016127 5 5 0,000 0,01875849 0,09656953 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,01875849 0,09630053 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,01875849 0,09603303 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,01875849 0,09576701 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,01875849 0,09550246 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,01875849 0,09523937 ! zymogen activation GO:0031638 5 5 0,000 0,01875849 0,09497772 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,01875849 0,09471751 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,01875849 0,09445872 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,01875849 0,09420134 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,01875849 0,09394535 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,01875849 0,09369076 ! nucleosome positioning GO:0016584 5 5 0,000 0,01875849 0,09343754 ! regulation of isotype switching GO:0045191 5 5 0,000 0,01875849 0,09318569 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,01875849 0,09293519 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,01875849 0,09268603 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,01875849 0,09243821 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,01875849 0,09219171 ! NADPH regeneration GO:0006740 5 5 0,000 0,01875849 0,09194652 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,01875849 0,09170263 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,01875849 0,09146003 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,01875849 0,09121871 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,01875849 0,09097866 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,01875849 0,09073987 ! sarcomere organization GO:0045214 5 5 0,000 0,01875849 0,09050233 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,01875849 0,09026603 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,01875849 0,09003096 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,01875849 0,08979712 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,01875849 0,08956448 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,01875849 0,08933305 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,01875849 0,08910281 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,01875849 0,08887375 ! spleen development GO:0048536 5 5 0,000 0,01875849 0,08864587 ! male genitalia development GO:0030539 5 5 0,000 0,01875849 0,08841916 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,01875849 0,0881936 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,01875849 0,08796919 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,01875849 0,08774592 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,01875849 0,08752377 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,01875849 0,08730275 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,01875849 0,08708285 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,01875849 0,08686405 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,01875849 0,08664634 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,01875849 0,08642973 ! ATP catabolic process GO:0006200 5 5 0,000 0,01875849 0,08621419 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01875849 0,08599973 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,01875849 0,08578633 ! blastocyst formation GO:0001825 5 5 0,000 0,01875849 0,08557399 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,01875849 0,08536269 ! embryonic gut development GO:0048566 5 5 0,000 0,01875849 0,08515244 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,01875849 0,08494322 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,01875849 0,08473503 ! activation of innate immune response GO:0002218 5 5 0,000 0,01875849 0,08452785 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,01875849 0,08432168 ! catecholamine transport GO:0051937 5 5 0,000 0,01875849 0,08411652 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,01875849 0,08391236 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,01875849 0,08370918 ! muscle adaptation GO:0043500 5 5 0,000 0,01875849 0,08350698 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,01875849 0,08330576 ! embryonic heart tube development GO:0035050 5 5 0,000 0,01875849 0,08310551 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,01875849 0,08290621 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,01875849 0,08270787 ! defense response to fungus GO:0050832 5 5 0,000 0,01875849 0,08251048 ! lysogeny GO:0030069 5 5 0,000 0,01875849 0,08231403 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,01875849 0,0821185 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,01875849 0,08192391 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,01875849 0,08173024 ! response to nicotine GO:0035094 5 5 0,000 0,01875849 0,08153748 ! establishment of cell polarity GO:0030010 5 5 0,000 0,01875849 0,08134562 ! mitochondrion localization GO:0051646 5 5 0,000 0,01875849 0,08115467 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,01875849 0,08096461 ! regulation of binding GO:0051098 60 57 1,000 0,01929673 0,08309318 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,02192298 0,09418195 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,02246936 0,09630474 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,02246936 0,09608129 ! tRNA modification GO:0006400 6 6 0,000 0,02246936 0,09585888 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,02246936 0,0956375 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,02246936 0,09541714 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,02246936 0,09519779 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,02246936 0,09497944 ! virus-host interaction GO:0019048 6 6 0,000 0,02246936 0,0947621 ! regulation of S phase GO:0033261 6 6 0,000 0,02246936 0,09454575 ! myotube differentiation GO:0014902 6 6 0,000 0,02246936 0,09433038 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,02246936 0,09411599 ! bone remodeling GO:0046849 6 6 0,000 0,02246936 0,09390258 ! N-glycan processing GO:0006491 6 6 0,000 0,02246936 0,09369013 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,02246936 0,09347864 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,02246936 0,0932681 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,02246936 0,09305851 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,02246936 0,09284986 ! RNA methylation GO:0001510 6 6 0,000 0,02246936 0,09264214 ! cartilage condensation GO:0001502 7 6 0,000 0,02246936 0,09243535 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,02246936 0,09222948 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,02246936 0,09202453 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,02246936 0,09182048 ! artery development GO:0060840 6 6 0,000 0,02246936 0,09161734 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,02246936 0,09141509 ! bile acid metabolic process GO:0008206 6 6 0,000 0,02246936 0,09121374 ! androgen metabolic process GO:0008209 6 6 0,000 0,02246936 0,09101327 ! estrogen metabolic process GO:0008210 6 6 0,000 0,02246936 0,09081368 ! limbic system development GO:0021761 7 6 0,000 0,02246936 0,09061496 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,02246936 0,09041711 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,02246936 0,09022012 ! pathogenesis GO:0009405 6 6 0,000 0,02246936 0,09002399 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,02246936 0,08982871 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,02246936 0,08963428 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,02246936 0,08944068 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,02246936 0,08924792 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,02246936 0,08905599 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,02246936 0,08886489 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,02246936 0,0886746 ! arginine metabolic process GO:0006525 6 6 0,000 0,02246936 0,08848512 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,02246936 0,08829645 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,02246936 0,08810859 ! glutamate catabolic process GO:0006538 7 6 0,000 0,02246936 0,08792152 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,02246936 0,08773525 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,02246936 0,08754976 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,02246936 0,08736506 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,02246936 0,08718113 ! V(D)J recombination GO:0033151 6 6 0,000 0,02246936 0,08699798 ! focal adhesion formation GO:0048041 7 6 0,000 0,02246936 0,08681559 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,02246936 0,08663397 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,02246936 0,0864531 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,02246936 0,08627299 ! regulation of heart rate GO:0002027 6 6 0,000 0,02246936 0,08609363 ! lipid digestion GO:0044241 6 6 0,000 0,02246936 0,08591501 ! asymmetric protein localization GO:0008105 6 6 0,000 0,02246936 0,08573714 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,02246936 0,08555999 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,02246936 0,08538358 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,02246936 0,08520789 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,02246936 0,08503293 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,02246936 0,08485868 ! ruffle organization GO:0031529 6 6 0,000 0,02246936 0,08468515 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,02246936 0,08451232 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,02246936 0,0843402 ! neutral amino acid transport GO:0015804 6 6 0,000 0,02246936 0,08416877 ! L-amino acid transport GO:0015807 6 6 0,000 0,02246936 0,08399805 ! bone mineralization GO:0030282 6 6 0,000 0,02246936 0,08382801 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,02246936 0,08365866 ! negative regulation of ossification GO:0030279 6 6 0,000 0,02246936 0,08348999 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,02246936 0,08332201 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,02246936 0,08315469 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,02246936 0,08298805 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,02246936 0,08282207 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,02246936 0,08265676 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,02246936 0,08249211 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,02246936 0,08232811 ! regulation of organ growth GO:0046620 6 6 0,000 0,02246936 0,08216476 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,02246936 0,08200205 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,02246936 0,08183999 ! response to dsRNA GO:0043331 6 6 0,000 0,02246936 0,08167857 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,02246936 0,08151779 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,02246936 0,08135764 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,02246936 0,08119811 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,02246936 0,08103921 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,02246936 0,08088093 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,02246936 0,08072327 ! multicellular organismal aging GO:0010259 6 6 0,000 0,02246936 0,08056622 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,02246936 0,08040978 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,02246936 0,08025395 ! erythrocyte development GO:0048821 6 6 0,000 0,02246936 0,08009872 ! renal water homeostasis GO:0003091 6 6 0,000 0,02246936 0,07994409 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,02246936 0,07979005 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,02246936 0,07963661 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,02246936 0,07948376 ! ribosome assembly GO:0042255 6 6 0,000 0,02246936 0,07933149 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,02246936 0,0791798 ! diencephalon development GO:0021536 6 6 0,000 0,02246936 0,0790287 ! fucose catabolic process GO:0019317 6 6 0,000 0,02246936 0,07887817 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,02246936 0,07872821 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,02246936 0,07857882 ! regulation of lipid transport GO:0032368 6 6 0,000 0,02246936 0,07842999 ! regulation of cell division GO:0051302 6 6 0,000 0,02246936 0,07828173 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,02246936 0,07813403 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,02246936 0,07798689 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,02246936 0,07784029 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,02246936 0,07769425 ! neuroblast proliferation GO:0007405 6 6 0,000 0,02246936 0,07754876 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,02246936 0,07740381 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,02246936 0,0772594 ! regulation of glucose transport GO:0010827 6 6 0,000 0,02246936 0,07711552 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,02246936 0,07697219 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,02246936 0,07682938 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,02246936 0,07668711 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,02246936 0,07654535 ! thymus development GO:0048538 6 6 0,000 0,02246936 0,07640413 ! lymph node development GO:0048535 6 6 0,000 0,02246936 0,07626342 ! organic cation transport GO:0015695 6 6 0,000 0,02246936 0,07612323 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,02246936 0,07598355 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,02246936 0,07584439 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,02246936 0,07570573 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,02246936 0,07556759 ! sperm-egg recognition GO:0035036 7 6 0,000 0,02246936 0,07542994 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,02246936 0,07529279 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,02246936 0,07515615 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,02246936 0,07501999 ! alditol metabolic process GO:0019400 6 6 0,000 0,02246936 0,07488433 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,02246936 0,07474916 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,02246936 0,07461448 ! maternal placenta development GO:0001893 6 6 0,000 0,02246936 0,07448028 ! regulation of embryonic development GO:0045995 6 6 0,000 0,02246936 0,07434657 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,02246936 0,07421333 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,02260164 0,07451668 ! glucose metabolic process GO:0006006 63 63 1,000 0,023289 0,07664575 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,02398498 0,07879558 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,02540255 0,0833041 ! respiratory burst GO:0045730 7 7 0,000 0,02616674 0,08565774 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,02616674 0,08550587 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,02616674 0,08535453 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,02616674 0,08520373 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,02616674 0,08505346 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,02616674 0,08490371 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,02616674 0,0847545 ! regulation of chemokine production GO:0032642 7 7 0,000 0,02616674 0,08460581 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,02616674 0,08445764 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,02616674 0,08430998 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,02616674 0,08416284 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,02616674 0,08401622 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,02616674 0,0838701 ! gene silencing by RNA GO:0031047 7 7 0,000 0,02616674 0,0837245 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,02616674 0,08357939 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,02616674 0,08343479 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,02616674 0,08329069 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,02616674 0,08314709 ! axis specification GO:0009798 7 7 0,000 0,02616674 0,08300398 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,02616674 0,08286136 ! visual behavior GO:0007632 7 7 0,000 0,02616674 0,08271923 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,02616674 0,08257759 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,02616674 0,08243643 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,02616674 0,08229575 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,02616674 0,08215555 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,02616674 0,08201583 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,02616674 0,08187659 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,02616674 0,08173781 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,02616674 0,08159951 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,02616674 0,08146167 ! digestive system development GO:0055123 7 7 0,000 0,02616674 0,0813243 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,02616674 0,08118739 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,02616674 0,08105094 ! protein targeting to ER GO:0045047 8 7 0,000 0,02616674 0,08091495 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,02616674 0,08077941 ! endoderm development GO:0007492 7 7 0,000 0,02616674 0,08064433 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,02616674 0,0805097 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,02616674 0,08037552 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,02616674 0,08024178 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,02616674 0,08010849 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,02616674 0,07997564 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,02616674 0,07984323 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,02616674 0,07971126 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,02616674 0,07957972 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,02616674 0,07944862 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,02616674 0,07931794 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,02616674 0,0791877 ! response to X-ray GO:0010165 7 7 0,000 0,02616674 0,07905789 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,02616674 0,07892849 ! UV protection GO:0009650 7 7 0,000 0,02616674 0,07879953 ! DNA integration GO:0015074 7 7 0,000 0,02616674 0,07867098 ! myofibril assembly GO:0030239 7 7 0,000 0,02616674 0,07854285 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,02616674 0,07841514 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,02616674 0,07828784 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,02616674 0,07816096 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,02616674 0,07803448 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,02616674 0,07790842 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,02616674 0,07778276 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,02616674 0,0776575 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,02616674 0,07753265 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,02616674 0,0774082 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,02616674 0,07728415 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,02616674 0,0771605 ! axon cargo transport GO:0008088 7 7 0,000 0,02616674 0,07703724 ! eating behavior GO:0042755 7 7 0,000 0,02616674 0,07691437 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,02616674 0,07679189 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,02616674 0,07666981 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,02616674 0,07654811 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,02616674 0,0764268 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,02616674 0,07630587 ! cranial nerve development GO:0021545 7 7 0,000 0,02616674 0,07618532 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,02616674 0,07606516 ! induction of an organ GO:0001759 7 7 0,000 0,02616674 0,07594537 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,02616674 0,07582596 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,02616674 0,07570692 ! autonomic nervous system development GO:0048483 7 7 0,000 0,02616674 0,07558826 ! intracellular lipid transport GO:0032365 7 7 0,000 0,02616674 0,07546997 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,02616674 0,07535205 ! platelet activation GO:0030168 8 7 0,000 0,02616674 0,07523449 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,02616674 0,07511731 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,02616674 0,07500048 ! natural killer cell activation GO:0030101 7 7 0,000 0,02616674 0,07488402 ! response to gamma radiation GO:0010332 8 7 0,000 0,02616674 0,07476792 ! NADP metabolic process GO:0006739 7 7 0,000 0,02616674 0,07465218 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,02616674 0,0745368 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,02616674 0,07442177 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,02616674 0,0743071 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,02616674 0,07419278 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,02616674 0,07407882 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,02616674 0,0739652 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,02616674 0,07385193 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,02616674 0,07373901 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,02616674 0,07362643 ! cell-cell recognition GO:0009988 8 7 0,000 0,02616674 0,07351419 ! hormone catabolic process GO:0042447 7 7 0,000 0,02616674 0,0734023 ! dopamine metabolic process GO:0042417 7 7 0,000 0,02616674 0,07329074 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,02616674 0,07317953 ! oxygen transport GO:0015671 7 7 0,000 0,02616674 0,07306865 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,02616674 0,07295811 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,02616674 0,0728479 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,02616674 0,07273802 ! regulation of axon extension GO:0030516 7 7 0,000 0,02616674 0,07262848 ! cell killing GO:0001906 7 7 0,000 0,02616674 0,07251926 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,02616674 0,07241038 ! adult feeding behavior GO:0008343 7 7 0,000 0,02616674 0,07230181 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,02616674 0,07219358 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,02616674 0,07208567 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,02616674 0,07197807 ! response to cold GO:0009409 7 7 0,000 0,02616674 0,0718708 ! response to radiation GO:0009314 70 68 1,000 0,0268538 0,07364815 ! regionalization GO:0003002 70 69 1,000 0,02759189 0,07555995 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,02759189 0,07544784 ! regulation of cell migration GO:0030334 71 71 1,000 0,02909263 0,07943366 ! regulation of cell activation GO:0050865 71 71 1,000 0,02909263 0,07931616 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,02985068 0,08126262 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,02985068 0,08114277 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,02985068 0,08102326 ! positive regulation of translation GO:0045727 8 8 0,000 0,02985068 0,08090411 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,02985068 0,08078531 ! superoxide anion generation GO:0042554 8 8 0,000 0,02985068 0,08066686 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,02985068 0,08054875 ! cGMP metabolic process GO:0046068 8 8 0,000 0,02985068 0,08043099 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,02985068 0,08031357 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,02985068 0,0801965 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,02985068 0,08007976 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,02985068 0,07996337 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,02985068 0,07984731 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,02985068 0,07973159 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,02985068 0,0796162 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,02985068 0,07950115 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,02985068 0,07938643 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,02985068 0,07927204 ! lipid localization GO:0010876 8 8 0,000 0,02985068 0,07915798 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,02985068 0,07904425 ! response to cAMP GO:0051591 8 8 0,000 0,02985068 0,07893084 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,02985068 0,07881776 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,02985068 0,078705 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,02985068 0,07859257 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,02985068 0,07848045 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,02985068 0,07836866 ! sensory perception of taste GO:0050909 8 8 0,000 0,02985068 0,07825718 ! organelle fusion GO:0048284 8 8 0,000 0,02985068 0,07814602 ! pancreas development GO:0031016 8 8 0,000 0,02985068 0,07803517 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,02985068 0,07792464 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,02985068 0,07781442 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,02985068 0,07770451 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,02985068 0,07759492 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,02985068 0,07748563 ! sperm motility GO:0030317 8 8 0,000 0,02985068 0,07737665 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,02985068 0,07726797 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,02985068 0,0771596 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,02985068 0,07705154 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,02985068 0,07694377 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,02985068 0,07683631 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,02985068 0,07672914 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,02985068 0,07662228 ! Golgi organization GO:0007030 8 8 0,000 0,02985068 0,07651571 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,02985068 0,07640944 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,02985068 0,07630346 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,02985068 0,07619778 ! fructose metabolic process GO:0006000 8 8 0,000 0,02985068 0,07609239 ! mannose metabolic process GO:0006013 9 8 0,000 0,02985068 0,07598729 ! NAD metabolic process GO:0019674 8 8 0,000 0,02985068 0,07588248 ! sex determination GO:0007530 8 8 0,000 0,02985068 0,07577796 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,02985068 0,07567372 ! plasma membrane fusion GO:0045026 8 8 0,000 0,02985068 0,07556978 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,02985068 0,07546611 ! response to fungus GO:0009620 8 8 0,000 0,02985068 0,07536274 ! stem cell differentiation GO:0048863 8 8 0,000 0,02985068 0,07525964 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,02985068 0,07515683 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,02985068 0,07505429 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,02985068 0,07495204 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,02985068 0,07485006 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,02985068 0,07474836 ! regulation of vasodilation GO:0042312 8 8 0,000 0,02985068 0,07464694 ! vasoconstriction GO:0042310 8 8 0,000 0,02985068 0,07454579 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,02985068 0,07444492 ! muscle cell development GO:0055001 8 8 0,000 0,02985068 0,07434432 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,02985068 0,07424399 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,02985068 0,07414393 ! sensory perception of pain GO:0019233 8 8 0,000 0,02985068 0,07404414 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,02985068 0,07394462 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,02985068 0,07384536 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,02985068 0,07374638 ! chromatin silencing GO:0006342 8 8 0,000 0,02985068 0,07364765 ! tissue regeneration GO:0042246 8 8 0,000 0,02985068 0,07354919 ! salivary gland development GO:0007431 8 8 0,000 0,02985068 0,073451 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,02985068 0,07335306 ! T cell homeostasis GO:0043029 8 8 0,000 0,02985068 0,07325539 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,02985068 0,07315797 ! water homeostasis GO:0030104 8 8 0,000 0,02985068 0,07306082 ! cofactor transport GO:0051181 8 8 0,000 0,02985068 0,07296392 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,02985068 0,07286728 ! acid secretion GO:0046717 8 8 0,000 0,02985068 0,07277089 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,02985068 0,07267476 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,02985068 0,07257889 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,02985068 0,07248326 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,02985068 0,07238789 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,02985068 0,07229277 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,02985068 0,0721979 ! regulation of RNA stability GO:0043487 8 8 0,000 0,02985068 0,07210327 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,02985068 0,0720089 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,02985068 0,07191477 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,02985068 0,07182088 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 0,02985068 0,07172724 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,02985068 0,07163385 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,02985068 0,0715407 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,02985068 0,07144779 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,02985068 0,07135512 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,02985068 0,07126269 ! developmental induction GO:0031128 8 8 0,000 0,02985068 0,0711705 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,02985068 0,07107855 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,02985068 0,07098683 ! actin filament polymerization GO:0030041 9 8 0,000 0,02985068 0,07089536 ! peptide hormone processing GO:0016486 8 8 0,000 0,02985068 0,07080411 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,02985068 0,07071311 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,02985068 0,07062233 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,02985516 0,07054238 ! lactation GO:0007595 10 9 0,000 0,03352121 0,07910318 ! embryonic pattern specification GO:0009880 10 9 0,000 0,03352121 0,07900202 ! positive regulation of cell size GO:0045793 9 9 0,000 0,03352121 0,07890113 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,03352121 0,07880049 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,03352121 0,07870011 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,03352121 0,07859998 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,03352121 0,07850011 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,03352121 0,07840049 ! viral genome replication GO:0019079 9 9 0,000 0,03352121 0,07830112 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,03352121 0,078202 ! copper ion transport GO:0006825 9 9 0,000 0,03352121 0,07810314 ! lipid phosphorylation GO:0046834 9 9 0,000 0,03352121 0,07800452 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,03352121 0,07790616 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,03352121 0,07780804 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,03352121 0,07771017 ! RNA polyadenylation GO:0043631 9 9 0,000 0,03352121 0,07761254 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,03352121 0,07751516 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,03352121 0,07741802 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,03352121 0,07732113 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,03352121 0,07722448 ! phospholipid efflux GO:0033700 9 9 0,000 0,03352121 0,07712807 ! response to alkaloid GO:0043279 10 9 0,000 0,03352121 0,0770319 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,03352121 0,07693597 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,03352121 0,07684028 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,03352121 0,07674482 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,03352121 0,07664961 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,03352121 0,07655463 ! response to ethanol GO:0045471 9 9 0,000 0,03352121 0,07645988 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,03352121 0,07636537 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,03352121 0,07627109 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,03352121 0,07617704 ! methionine metabolic process GO:0006555 9 9 0,000 0,03352121 0,07608323 ! glutamine metabolic process GO:0006541 9 9 0,000 0,03352121 0,07598965 ! response to osmotic stress GO:0006970 9 9 0,000 0,03352121 0,07589629 ! pigmentation during development GO:0048066 9 9 0,000 0,03352121 0,07580317 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,03352121 0,07571027 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,03352121 0,07561761 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,03352121 0,07552516 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,03352121 0,07543295 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,03352121 0,07534096 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,03352121 0,07524919 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,03352121 0,07515764 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,03352121 0,07506632 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,03352121 0,07497522 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,03352121 0,07488434 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,03352121 0,07479368 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,03352121 0,07470324 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,03352121 0,07461302 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,03352121 0,07452302 ! DNA replication initiation GO:0006270 9 9 0,000 0,03352121 0,07443323 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,03352121 0,07434366 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,03352121 0,07425431 ! regulation of cellular pH GO:0030641 9 9 0,000 0,03352121 0,07416517 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,03352121 0,07407624 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,03352121 0,07398753 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,03352121 0,07389902 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,03352121 0,07381073 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,03352121 0,07372265 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,03352121 0,07363478 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,03352121 0,07354712 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,03352121 0,07345967 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,03352121 0,07337243 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,03352121 0,07328539 ! collagen catabolic process GO:0030574 9 9 0,000 0,03352121 0,07319856 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,03352121 0,07311193 ! purine base metabolic process GO:0006144 9 9 0,000 0,03352121 0,07302551 ! gas transport GO:0015669 9 9 0,000 0,03352121 0,0729393 ! cholesterol efflux GO:0033344 9 9 0,000 0,03352121 0,07285328 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,03352121 0,07276747 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,03352121 0,07268186 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,03352121 0,07259646 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,03352121 0,07251125 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,03352121 0,07242624 ! defense response to virus GO:0051607 9 9 0,000 0,03352121 0,07234143 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,03352121 0,07225682 ! actin filament-based movement GO:0030048 9 9 0,000 0,03352121 0,07217241 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,03352121 0,0720882 ! regulation of protein modification process GO:0031399 79 78 1,000 0,0345963 0,0743135 ! regulation of locomotion GO:0040012 79 79 1,000 0,03541355 0,0759804 ! regulation of cell motion GO:0051270 79 79 1,000 0,03541355 0,07589205 ! tube development GO:0035295 83 81 1,000 0,03707064 0,07935097 ! lymphocyte activation GO:0046649 82 81 1,000 0,03707064 0,07925891 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,03717838 0,07939717 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,03717838 0,07930527 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,03717838 0,07921359 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,03717838 0,07912212 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,03717838 0,07903086 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,03717838 0,07893981 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,03717838 0,07884897 ! neuron maturation GO:0042551 10 10 0,000 0,03717838 0,07875834 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,03717838 0,07866792 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,03717838 0,0785777 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,03717838 0,07848769 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,03717838 0,07839789 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,03717838 0,07830829 ! hormone secretion GO:0046879 10 10 0,000 0,03717838 0,0782189 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,03717838 0,07812971 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,03717838 0,07804073 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,03717838 0,07795194 ! cAMP metabolic process GO:0046058 10 10 0,000 0,03717838 0,07786336 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,03717838 0,07777498 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,03717838 0,0776868 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,03717838 0,07759882 ! glial cell development GO:0021782 10 10 0,000 0,03717838 0,07751104 ! phototransduction GO:0007602 11 10 0,000 0,03717838 0,07742345 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,03717838 0,07733607 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,03717838 0,07724888 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,03717838 0,07716189 ! fat cell differentiation GO:0045444 10 10 0,000 0,03717838 0,07707509 ! myoblast differentiation GO:0045445 10 10 0,000 0,03717838 0,07698849 ! centrosome cycle GO:0007098 10 10 0,000 0,03717838 0,07690208 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,03717838 0,07681587 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,03717838 0,07672985 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,03717838 0,07664402 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,03717838 0,07655839 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,03717838 0,07647294 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,03717838 0,07638769 ! protein polyubiquitination GO:0000209 10 10 0,000 0,03717838 0,07630262 ! glutamate metabolic process GO:0006536 11 10 0,000 0,03717838 0,07621775 ! plasma membrane organization GO:0007009 10 10 0,000 0,03717838 0,07613306 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,03717838 0,07604856 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,03717838 0,07596425 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,03717838 0,07588013 GO:0030968|endoplasmic reticulum unfolded protein response, ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,03717838 0,07579619 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,03717838 0,07571244 ! exocrine system development GO:0035272 10 10 0,000 0,03717838 0,07562887 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,03717838 0,07554549 ! embryo implantation GO:0007566 11 10 0,000 0,03717838 0,07546229 ! regulation of protein binding GO:0043393 11 10 0,000 0,03717838 0,07537927 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,03717838 0,07529644 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,03717838 0,07521378 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,03717838 0,07513131 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,03717838 0,07504902 ! protein export from nucleus GO:0006611 10 10 0,000 0,03717838 0,07496691 ! negative regulation of immune response GO:0050777 10 10 0,000 0,03717838 0,07488498 ! cytolysis GO:0019835 10 10 0,000 0,03717838 0,07480323 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,03717838 0,07472165 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,03717838 0,07464026 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,03717838 0,07455904 ! histone deacetylation GO:0016575 10 10 0,000 0,03717838 0,074478 ! mRNA splice site selection GO:0006376 11 10 0,000 0,03717838 0,07439713 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,03717838 0,07431644 ! gland morphogenesis GO:0022612 10 10 0,000 0,03717838 0,07423592 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,03717838 0,07415558 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,03717838 0,07407541 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,03717838 0,07399542 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,03717838 0,0739156 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,03717838 0,07383594 ! regulation of epidermis development GO:0045682 10 10 0,000 0,03717838 0,07375647 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,03717838 0,07367716 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,03717838 0,07359802 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,03717838 0,07351905 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,03717838 0,07344025 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,03717838 0,07336162 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,03717838 0,07328316 ! nerve development GO:0021675 10 10 0,000 0,03717838 0,07320487 ! gut development GO:0048565 10 10 0,000 0,03717838 0,07312674 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,03717838 0,07304878 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,03717838 0,07297099 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,03717838 0,07289336 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,03717838 0,07281589 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,03717838 0,0727386 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,03717838 0,07266146 ! protein stabilization GO:0050821 10 10 0,000 0,03717838 0,07258449 ! protein secretion GO:0009306 11 11 0,000 0,04082225 0,07961418 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,04082225 0,07953002 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,04082225 0,07944604 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,04082225 0,07936224 ! negative regulation of defense response GO:0031348 11 11 0,000 0,04082225 0,07927861 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,04082225 0,07919516 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,04082225 0,07911188 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,04082225 0,07902878 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,04082225 0,07894586 ! skin development GO:0043588 11 11 0,000 0,04082225 0,07886311 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,04082225 0,07878053 ! signal complex assembly GO:0007172 11 11 0,000 0,04082225 0,07869812 ! microtubule-based transport GO:0010970 11 11 0,000 0,04082225 0,07861589 ! endothelial cell migration GO:0043542 11 11 0,000 0,04082225 0,07853382 ! peroxisomal transport GO:0043574 11 11 0,000 0,04082225 0,07845193 ! protein amino acid methylation GO:0006479 11 11 0,000 0,04082225 0,07837021 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,04082225 0,07828866 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,04082225 0,07820728 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! T cell proliferation GO:0042098 11 11 0,000 0,04082225 0,07812607 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,04082225 0,07804502 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,04082225 0,07796415 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,04082225 0,07788344 ! spinal cord development GO:0021510 11 11 0,000 0,04082225 0,0778029 ! smooth muscle contraction GO:0006939 11 11 0,000 0,04082225 0,07772252 ! cellular response to starvation GO:0009267 11 11 0,000 0,04082225 0,07764231 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,04082225 0,07756227 ! digestive system process GO:0022600 11 11 0,000 0,04082225 0,07748239 ! mitotic spindle organization GO:0007052 11 11 0,000 0,04082225 0,07740268 ! fucose metabolic process GO:0006004 11 11 0,000 0,04082225 0,07732313 ! membrane budding GO:0006900 11 11 0,000 0,04082225 0,07724374 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,04082225 0,07716452 ! monoamine transport GO:0015844 11 11 0,000 0,04082225 0,07708545 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,04082225 0,07700655 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,04082225 0,07692781 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,04082225 0,07684924 ! body fluid secretion GO:0007589 11 11 0,000 0,04082225 0,07677082 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,04082225 0,07669256 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,04082225 0,07661446 ! intermediate filament-based process GO:0045103 11 11 0,000 0,04082225 0,07653652 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,04082225 0,07645874 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,04082225 0,07638112 ! membrane depolarization GO:0051899 11 11 0,000 0,04082225 0,07630365 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,04082225 0,07622635 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,04082225 0,07614919 ! oogenesis GO:0048477 11 11 0,000 0,04082225 0,0760722 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,04082225 0,07599536 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,04082225 0,07591867 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,04082225 0,07584214 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,04082225 0,07576576 ! muscle maintenance GO:0046716 12 11 0,000 0,04082225 0,07568954 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,04082225 0,07561347 ! hindbrain development GO:0030902 11 11 0,000 0,04082225 0,07553755 ! steroid catabolic process GO:0006706 11 11 0,000 0,04082225 0,07546179 ! endocrine process GO:0050886 11 11 0,000 0,04082225 0,07538617 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,04082225 0,07531071 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,04082225 0,0752354 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,04082225 0,07516024 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,04082225 0,07508523 ! hexose metabolic process GO:0019318 87 86 1,000 0,04134227 0,0759659 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 1,000 0,04134227 0,07589024 ! male gamete generation GO:0048232 90 88 1,000 0,04310117 0,07904025 GO:0007283|spermatogenesis, ! translational initiation GO:0006413 12 12 0,000 0,04445285 0,08143798 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,04445285 0,08135711 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,04445285 0,0812764 ! initiation of viral infection GO:0019059 12 12 0,000 0,04445285 0,08119584 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,04445285 0,08111545 ! iron ion transport GO:0006826 13 12 0,000 0,04445285 0,08103522 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,04445285 0,08095514 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,04445285 0,08087523 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,04445285 0,08079547 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,04445285 0,08071587 ! collagen metabolic process GO:0032963 12 12 0,000 0,04445285 0,08063642 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,04445285 0,08055714 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,04445285 0,080478 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,04445285 0,08039902 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,04445285 0,0803202 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,04445285 0,08024153 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,04445285 0,08016302 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,04445285 0,08008466 ! actomyosin structure organization GO:0031032 12 12 0,000 0,04445285 0,08000645 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,04445285 0,0799284 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,04445285 0,07985049 ! retinoid metabolic process GO:0001523 12 12 0,000 0,04445285 0,07977274 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,04445285 0,07969514 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,04445285 0,07961769 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,04445285 0,07954039 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,04445285 0,07946325 ! acute-phase response GO:0006953 12 12 0,000 0,04445285 0,07938625 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,04445285 0,0793094 ! vacuolar transport GO:0007034 12 12 0,000 0,04445285 0,07923269 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,04445285 0,07915614 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,04445285 0,07907974 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,04445285 0,07900348 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,04445285 0,07892737 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,04445285 0,0788514 ! male gonad development GO:0008584 12 12 0,000 0,04445285 0,07877558 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,04445285 0,07869991 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,04445285 0,07862438 ! renal system process GO:0003014 12 12 0,000 0,04445285 0,078549 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,04445285 0,07847376 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,04445285 0,07839867 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,04445285 0,07832372 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,04445285 0,07824891 ! cell fate determination GO:0001709 12 12 0,000 0,04445285 0,07817424 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,04445285 0,07809972 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,04445285 0,07802534 ! G1 phase GO:0051318 13 12 0,000 0,04445285 0,0779511 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,04445285 0,077877 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,04445285 0,07780305 ! detection of light stimulus GO:0009583 13 12 0,000 0,04445285 0,07772923 ! synaptogenesis GO:0007416 12 12 0,000 0,04445285 0,07765555 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,04445285 0,07758201 ! hormone transport GO:0009914 12 12 0,000 0,04445285 0,07750862 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,04445285 0,07743536 ! heme biosynthetic process GO:0006783 12 12 0,000 0,04445285 0,07736223 ! spermatid differentiation GO:0048515 13 12 0,000 0,04445285 0,07728925 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,04445285 0,07721641 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,04445285 0,0771437 ! neural tube closure GO:0001843 13 12 0,000 0,04445285 0,07707113 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,04445285 0,07699869 ! negative regulation of translation GO:0017148 12 12 0,000 0,04445285 0,07692639 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,04445285 0,07685423 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,04445285 0,0767822 ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 0,04488804 0,0774613 ! negative regulation of cell cycle GO:0045786 92 91 1,000 0,04579182 0,07894698 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,04670241 0,08044162 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,04807024 0,08272031 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,04807024 0,08264315 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,04807024 0,08256613 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,04807024 0,08248925 ! phenol metabolic process GO:0018958 13 13 0,000 0,04807024 0,08241252 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,04807024 0,08233592 ! gluconeogenesis GO:0006094 13 13 0,000 0,04807024 0,08225947 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,04807024 0,08218317 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,04807024 0,082107 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,04807024 0,08203098 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,04807024 0,08195509 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,04807024 0,08187935 ! regeneration GO:0031099 13 13 0,000 0,04807024 0,08180374 ! keratinization GO:0031424 13 13 0,000 0,04807024 0,08172828 ! post-embryonic development GO:0009791 14 13 0,000 0,04807024 0,08165295 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,04807024 0,08157777 ! patterning of blood vessels GO:0001569 13 13 0,000 0,04807024 0,08150272 ! vasculogenesis GO:0001570 13 13 0,000 0,04807024 0,08142781 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,04807024 0,08135303 ! regulation of innate immune response GO:0045088 13 13 0,000 0,04807024 0,0812784 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,04807024 0,0812039 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,04807024 0,08112954 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,04807024 0,08105531 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,04807024 0,08098122 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,04807024 0,08090726 ! autophagy GO:0006914 13 13 0,000 0,04807024 0,08083344 ! receptor metabolic process GO:0043112 14 13 0,000 0,04807024 0,08075976 ! actin filament bundle formation GO:0051017 13 13 0,000 0,04807024 0,08068621 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,04807024 0,08061279 ! ureteric bud development GO:0001657 13 13 0,000 0,04807024 0,0805395 ! cell aging GO:0007569 13 13 0,000 0,04807024 0,08046635 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,04807024 0,08039333 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,04807024 0,08032045 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,04807024 0,08024769 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,04807024 0,08017507 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,04807024 0,08010258 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,04807024 0,08003022 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,04807024 0,07995799 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,04807024 0,07988589 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,04807024 0,07981392 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,04807024 0,07974208 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,04807024 0,07967037 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,04807024 0,07959879 ! vasodilation GO:0042311 14 13 0,000 0,04807024 0,07952734 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,04807024 0,07945601 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,04807024 0,07938482 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,04807024 0,07931375 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,04807024 0,0792428 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,04807024 0,07917199 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,04807024 0,0791013 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,04807024 0,07903073 ! immunoglobulin production GO:0002377 13 13 0,000 0,04807024 0,0789603 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,04807024 0,07888999 ! cell-cell junction organization GO:0045216 13 13 0,000 0,04807024 0,0788198 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,04807024 0,07874974 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,04807024 0,0786798 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,04807024 0,07860999 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,04807024 0,0785403 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,04807024 0,07847073 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,04807024 0,07840129 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,04807024 0,07833197 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,04807024 0,07826277 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,04807024 0,07819369 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,04807024 0,07812474 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,04807024 0,07805591 ! blastocyst development GO:0001824 13 13 0,000 0,04807024 0,0779872 ! telomere organization GO:0032200 13 13 0,000 0,04807024 0,0779186 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,04807024 0,07785014 ! regulation of amine transport GO:0051952 13 13 0,000 0,04807024 0,07778179 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,04807024 0,07771356 ! protein tetramerization GO:0051262 13 13 0,000 0,04807024 0,07764545 ! pattern specification process GO:0007389 96 94 1,000 0,04854377 0,07834166 ! neuron fate commitment GO:0048663 14 14 0,000 0,05167446 0,08332111 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,05167446 0,08324828 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,05167446 0,08317557 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,05167446 0,08310299 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,05167446 0,08303054 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,05167446 0,08295821 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,05167446 0,08288601 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,05167446 0,08281394 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,05167446 0,08274199 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,05167446 0,08267016 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,05167446 0,08259846 ! vesicle docking GO:0048278 14 14 0,000 0,05167446 0,08252689 ! superoxide metabolic process GO:0006801 15 14 0,000 0,05167446 0,08245544 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,05167446 0,08238411 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,05167446 0,0823129 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,05167446 0,08224182 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,05167446 0,08217086 ! hair cycle GO:0042633 14 14 0,000 0,05167446 0,08210003 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,05167446 0,08202931 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,05167446 0,08195872 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,05167446 0,08188825 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,05167446 0,0818179 ! lysosome organization GO:0007040 14 14 0,000 0,05167446 0,08174767 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,05167446 0,08167756 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,05167446 0,08160757 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,05167446 0,0815377 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,05167446 0,08146795 ! primary neural tube formation GO:0014020 15 14 0,000 0,05167446 0,08139832 ! peptide cross-linking GO:0018149 14 14 0,000 0,05167446 0,0813288 ! regulation of behavior GO:0050795 14 14 0,000 0,05167446 0,08125941 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,05167446 0,08119014 ! base-excision repair GO:0006284 14 14 0,000 0,05167446 0,08112098 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,05167446 0,08105194 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,05167446 0,08098302 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,05167446 0,08091421 ! formation of primary germ layer GO:0001704 14 14 0,000 0,05167446 0,08084553 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,05167446 0,08077696 ! collagen fibril organization GO:0030199 14 14 0,000 0,05167446 0,0807085 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,05167446 0,08064016 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,05167446 0,08057194 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,05167446 0,08050383 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,05167446 0,08043584 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,05167446 0,08036796 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,05167446 0,08030019 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,05167446 0,08023254 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,05167446 0,08016501 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,05167446 0,08009759 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,05422519 0,08398069 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,05526556 0,08552008 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,05526556 0,08544834 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,05526556 0,08537671 ! positive regulation of ossification GO:0045778 15 15 0,000 0,05526556 0,08530521 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,05526556 0,08523382 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,05526556 0,08516256 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,05526556 0,08509141 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,05526556 0,08502038 ! response to vitamin GO:0033273 15 15 0,000 0,05526556 0,08494947 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,05526556 0,08487868 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,05526556 0,08480801 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,05526556 0,08473745 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,05526556 0,08466702 ! ovarian follicle development GO:0001541 15 15 0,000 0,05526556 0,08459669 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,05526556 0,08452649 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,05526556 0,0844564 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,05526556 0,08438643 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,05526556 0,08431657 ! heme metabolic process GO:0042168 15 15 0,000 0,05526556 0,08424683 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,05526556 0,08417721 ! chromosome condensation GO:0030261 15 15 0,000 0,05526556 0,0841077 ! response to starvation GO:0042594 15 15 0,000 0,05526556 0,0840383 ! response to ionizing radiation GO:0010212 16 15 0,000 0,05526556 0,08396902 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,05526556 0,08389985 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,05526556 0,0838308 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,05526556 0,08376186 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,05526556 0,08369303 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,05526556 0,08362432 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,05526556 0,08355572 ! phospholipid transport GO:0015914 15 15 0,000 0,05526556 0,08348723 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,05526556 0,08341885 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,05526556 0,08335059 ! glutathione metabolic process GO:0006749 16 15 0,000 0,05526556 0,08328244 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,05526556 0,0832144 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,05526556 0,08314646 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,05526556 0,08307865 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,05526556 0,08301094 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,05526556 0,08294334 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,05526556 0,08287585 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,05526556 0,08280847 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,05884357 0,08809806 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,05884357 0,08802655 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,05884357 0,08795516 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,05884357 0,08788388 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,05884357 0,08781272 ! learning GO:0007612 16 16 0,000 0,05884357 0,08774167 ! circadian rhythm GO:0007623 16 16 0,000 0,05884357 0,08767074 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,05884357 0,08759993 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,05884357 0,08752922 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,05884357 0,08745863 ! vacuole organization GO:0007033 16 16 0,000 0,05884357 0,08738816 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,05884357 0,0873178 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,05884357 0,08724755 ! vesicle targeting GO:0006903 17 16 0,000 0,05884357 0,08717742 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,05884357 0,0871074 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,05884357 0,08703749 ! iron ion homeostasis GO:0055072 16 16 0,000 0,05884357 0,08696769 ! positive regulation of cell development GO:0010720 16 16 0,000 0,05884357 0,086898 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,05884357 0,08682843 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,05884357 0,08675897 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,05884357 0,08668961 ! cell fate specification GO:0001708 16 16 0,000 0,05884357 0,08662037 ! pentose metabolic process GO:0019321 16 16 0,000 0,05884357 0,08655124 ! fatty acid transport GO:0015908 16 16 0,000 0,05884357 0,08648222 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,05884357 0,08641331 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,05884357 0,08634451 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,05884357 0,08627582 ! cofactor catabolic process GO:0051187 16 16 0,000 0,05884357 0,08620724 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,05884357 0,08613877 ! polyol metabolic process GO:0019751 16 16 0,000 0,05884357 0,0860704 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,05884357 0,08600215 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,05884357 0,085934 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,05884357 0,08586596 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,05884357 0,08579803 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,05884357 0,0857302 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,05884357 0,08566249 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,05884357 0,08559488 ! regulation of coagulation GO:0050818 17 16 0,000 0,05884357 0,08552737 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,06240856 0,09063749 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,06240856 0,09056612 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,06240856 0,09049487 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,06240856 0,09042372 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,06240856 0,09035269 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,06240856 0,09028177 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,06240856 0,09021096 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,06240856 0,09014026 ! sensory perception of smell GO:0007608 17 17 0,000 0,06240856 0,09006968 ! tissue remodeling GO:0048771 17 17 0,000 0,06240856 0,0899992 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,06240856 0,08992883 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,06240856 0,08985858 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,06240856 0,08978843 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,06240856 0,08971839 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,06240856 0,08964846 ! neural crest cell development GO:0014032 19 17 0,000 0,06240856 0,08957864 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,06240856 0,08950893 ! negative regulation of cell development GO:0010721 18 17 0,000 0,06240856 0,08943933 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,06240856 0,08936983 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,06240856 0,08930045 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,06240856 0,08923117 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,06240856 0,089162 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,06240856 0,08909293 ! pigmentation GO:0043473 17 17 0,000 0,06240856 0,08902398 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,06240856 0,08895513 ! adult locomotory behavior GO:0008344 17 17 0,000 0,06240856 0,08888638 ! embryonic organ development GO:0048568 17 17 0,000 0,06240856 0,08881774 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,06240856 0,08874921 ! liver development GO:0001889 17 17 0,000 0,06240856 0,08868078 ! gene silencing GO:0016458 17 17 0,000 0,06240856 0,08861246 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,06596056 0,09358377 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,06596056 0,09351178 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,06596056 0,0934399 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,06596056 0,09336814 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,06596056 0,09329648 ! membrane docking GO:0022406 18 18 0,000 0,06596056 0,09322493 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,06596056 0,0931535 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,06596056 0,09308217 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,06596056 0,09301095 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,06596056 0,09293984 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,06596056 0,09286884 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,06596056 0,09279795 ! striated muscle contraction GO:0006941 18 18 0,000 0,06596056 0,09272717 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,06596056 0,09265649 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,06596056 0,09258592 ! ceramide metabolic process GO:0006672 18 18 0,000 0,06596056 0,09251546 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,06596056 0,09244511 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! hexose biosynthetic process GO:0019319 18 18 0,000 0,06596056 0,09237486 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,06596056 0,09230472 ! B cell differentiation GO:0030183 18 18 0,000 0,06596056 0,09223468 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,06596056 0,09216476 ! BMP signaling pathway GO:0030509 18 18 0,000 0,06596056 0,09209493 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,06596056 0,09202522 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,06596056 0,09195561 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,06596056 0,0918861 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,06949962 0,09674305 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,06949962 0,09667004 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,06949962 0,09659713 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,06949962 0,09652434 ! glial cell differentiation GO:0010001 19 19 0,000 0,06949962 0,09645166 ! regulation of pH GO:0006885 19 19 0,000 0,06949962 0,09637908 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,06949962 0,09630662 ! feeding behavior GO:0007631 19 19 0,000 0,06949962 0,09623426 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,06949962 0,09616201 ! peroxisome organization GO:0007031 19 19 0,000 0,06949962 0,09608987 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,06949962 0,09601784 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,06949962 0,09594592 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,06949962 0,0958741 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,06949962 0,09580239 ! metanephros development GO:0001656 19 19 0,000 0,06949962 0,09573079 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,06949962 0,0956593 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,06949962 0,09558791 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,06949962 0,09551663 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,06949962 0,09544545 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,06949962 0,09537439 ! regulation of protein stability GO:0031647 19 19 0,000 0,06949962 0,09530342 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,06949962 0,09523257 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,06949962 0,09516181 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,06949962 0,09509117 ! eye morphogenesis GO:0048592 19 19 0,000 0,06949962 0,09502062 ! regulation of cell shape GO:0008360 21 19 0,000 0,06949962 0,09495019 ! placenta development GO:0001890 19 19 0,000 0,06949962 0,09487985 ! response to heat GO:0009408 19 19 0,000 0,06949962 0,09480962 ! vesicle localization GO:0051648 20 19 0,000 0,06949962 0,0947395 ! regulation of muscle development GO:0048634 21 20 0,000 0,07302578 0,09947267 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,07302578 0,0993992 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,07302578 0,09932585 ! negative regulation of binding GO:0051100 21 20 0,000 0,07302578 0,0992526 ! organic ether metabolic process GO:0018904 20 20 0,000 0,07302578 0,09917945 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,07302578 0,09910642 ! neural tube development GO:0021915 21 20 0,000 0,07302578 0,0990335 ! nucleus organization GO:0006997 20 20 0,000 0,07302578 0,09896068 ! phagocytosis GO:0006909 21 20 0,000 0,07302578 0,09888796 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,07302578 0,09881536 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,07302578 0,09874286 ! protein targeting to membrane GO:0006612 22 20 0,000 0,07302578 0,09867047 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,07302578 0,09859818 ! chromatin remodeling GO:0006338 20 20 0,000 0,07302578 0,098526 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,07302578 0,09845393 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,07302578 0,09838196 ! lipid oxidation GO:0034440 20 20 0,000 0,07302578 0,0983101 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,07302578 0,09823834 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,07302578 0,09816668 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,07302578 0,09809513 ! RNA modification GO:0009451 20 20 0,000 0,07302578 0,09802369 ! single fertilization GO:0007338 21 20 0,000 0,07302578 0,09795234 ! regulation of B cell activation GO:0050864 20 20 0,000 0,07302578 0,09788111 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,0765391 0,10251567 ! mRNA catabolic process GO:0006402 21 21 0,000 0,0765391 0,10244122 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,0765391 0,10236688 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,0765391 0,10229264 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,0765391 0,10221852 ! Notch signaling pathway GO:0007219 22 21 0,000 0,0765391 0,1021445 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,0765391 0,10207059 ! ear morphogenesis GO:0042471 21 21 0,000 0,0765391 0,10199679 ! organic anion transport GO:0015711 21 21 0,000 0,0765391 0,10192309 ! cholesterol transport GO:0030301 21 21 0,000 0,0765391 0,1018495 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,0765391 0,10177601 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,0765391 0,10170264 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,0765391 0,10162936 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,0765391 0,1015562 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,0765391 0,10148313 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,0765391 0,10141018 ! regulation of proteolysis GO:0030162 21 21 0,000 0,0765391 0,10133733 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,0765391 0,10126458 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,0765391 0,10119193 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,0765391 0,1011194 ! RNA export from nucleus GO:0006405 22 22 0,000 0,08003961 0,10566833 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,08003961 0,10559269 ! sister chromatid segregation GO:0000819 22 22 0,000 0,08003961 0,10551716 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,08003961 0,10544174 ! regulation of ion transport GO:0043269 22 22 0,000 0,08003961 0,10536642 ! odontogenesis GO:0042476 22 22 0,000 0,08003961 0,10529122 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,08003961 0,10521611 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,08003961 0,10514112 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,08003961 0,10506623 ! ovulation cycle process GO:0022602 22 22 0,000 0,08003961 0,10499145 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,08003961 0,10491678 ! cell chemotaxis GO:0060326 23 22 0,000 0,08003961 0,10484221 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,08003961 0,10476775 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,08003961 0,10469339 ! male sex differentiation GO:0046661 22 22 0,000 0,08003961 0,10461914 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,08003961 0,104545 ! biopolymer methylation GO:0043414 22 22 0,000 0,08003961 0,10447096 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,08003961 0,10439702 ! detection of external stimulus GO:0009581 23 22 0,000 0,08003961 0,10432319 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,08003961 0,10424946 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,08003961 0,10417584 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,08003961 0,10410232 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,08003961 0,10402891 ! aerobic respiration GO:0009060 22 22 0,000 0,08003961 0,1039556 ! cytokine production GO:0001816 22 22 0,000 0,08003961 0,10388239 ! cytokinesis GO:0000910 23 22 0,000 0,08003961 0,10380928 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,08003961 0,10373628 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,08352735 0,10818054 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,08352735 0,10810457 ! viral infectious cycle GO:0019058 23 23 0,000 0,08352735 0,10802871 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,08352735 0,10795295 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,08352735 0,1078773 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,08352735 0,10780176 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,08352735 0,10772632 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,08352735 0,10765099 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,08352735 0,10757576 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,08352735 0,10750064 ! endocrine system development GO:0035270 23 23 0,000 0,08352735 0,10742562 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,08352735 0,1073507 ! positive regulation of growth GO:0045927 23 23 0,000 0,08352735 0,1072759 ! female gonad development GO:0008585 23 23 0,000 0,08352735 0,10720119 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,08352735 0,10712659 ! lipid homeostasis GO:0055088 23 23 0,000 0,08352735 0,10705209 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,08352735 0,1069777 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,08352735 0,10690341 ! mitochondrial transport GO:0006839 24 24 0,000 0,08700238 0,11127369 ! gliogenesis GO:0042063 24 24 0,000 0,08700238 0,11119653 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,08700238 0,11111947 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,08700238 0,11104252 ! glucose homeostasis GO:0042593 24 24 0,000 0,08700238 0,11096567 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,08700238 0,11088893 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,08700238 0,1108123 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,08700238 0,11073577 ! ovulation cycle GO:0042698 24 24 0,000 0,08700238 0,11065935 ! fertilization GO:0009566 25 24 0,000 0,08700238 0,11058303 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,08700238 0,11050682 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,08700238 0,11043071 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,09046474 0,1147464 ! negative regulation of secretion GO:0051048 26 25 0,000 0,09046474 0,11466748 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,09046474 0,11458867 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,09046474 0,11450997 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,09046474 0,11443138 ! cellular component disassembly GO:0022411 26 25 0,000 0,09046474 0,1143529 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,09046474 0,11427452 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,09046474 0,11419625 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,09046474 0,11411808 ! excretion GO:0007588 25 25 0,000 0,09046474 0,11404003 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,09046474 0,11396208 ! gastrulation GO:0007369 25 25 0,000 0,09046474 0,11388424 ! heart morphogenesis GO:0003007 25 25 0,000 0,09046474 0,1138065 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,09046474 0,11372887 ! regulation of endocytosis GO:0030100 25 25 0,000 0,09046474 0,11365134 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,09046474 0,11357393 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,09046474 0,11349661 ! positive regulation of defense response GO:0031349 26 26 0,000 0,09391448 0,11774448 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,09391448 0,11766443 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,09391448 0,1175845 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,09391448 0,11750467 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,09391448 0,11742495 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,09391448 0,11734534 ! cellular defense response GO:0006968 26 26 0,000 0,09391448 0,11726584 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,09391448 0,11718644 ! double-strand break repair GO:0006302 27 26 0,000 0,09391448 0,11710716 ! regulation of protein secretion GO:0050708 26 26 0,000 0,09391448 0,11702798 ! germ cell development GO:0007281 27 26 0,000 0,09391448 0,1169489 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,09391448 0,11686994 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,09391448 0,11679108 ! response to insulin stimulus GO:0032868 28 26 0,000 0,09391448 0,11671233 ! chloride transport GO:0006821 27 27 0,000 0,09735163 0,12090232 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,09735163 0,12082091 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,09735163 0,1207396 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,09735163 0,1206584 ! peptide metabolic process GO:0006518 29 27 0,000 0,09735163 0,12057732 ! activation of caspase activity GO:0006919 27 27 0,000 0,09735163 0,12049634 ! inner ear development GO:0048839 27 27 0,000 0,09735163 0,12041547 ! defense response to bacterium GO:0042742 27 27 0,000 0,09735163 0,12033471 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,09735163 0,12025405 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,09735163 0,12017351 ! cell growth GO:0016049 27 27 0,000 0,09735163 0,12009307 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,10077624 0,12423452 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,10077624 0,12415147 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,10077624 0,12406854 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,10077624 0,12398572 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,10077624 0,123903 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,10077624 0,1238204 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,10077624 0,12373791 ! developmental growth GO:0048589 28 28 0,000 0,10077624 0,12365553 ! cartilage development GO:0051216 29 28 0,000 0,10077624 0,12357326 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,10418835 0,1276723 ! viral reproductive process GO:0022415 29 29 0,000 0,10418835 0,12758746 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,10418835 0,12750274 ! leukocyte migration GO:0050900 30 29 0,000 0,10418835 0,12741814 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,10418835 0,12733364 ! antigen processing and presentation GO:0019882 29 29 0,000 0,10418835 0,12724926 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,10418835 0,12716499 ! tRNA processing GO:0008033 29 29 0,000 0,10418835 0,12708083 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,10418835 0,12699678 ! adult behavior GO:0030534 30 29 0,000 0,10418835 0,12691284 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,10418835 0,12682902 ! RNA catabolic process GO:0006401 30 30 0,000 0,10758802 0,130881 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,10758802 0,13079467 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,10758802 0,13070845 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,10758802 0,13062234 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,10758802 0,13053635 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,10758802 0,13045047 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,10758802 0,1303647 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,10758802 0,13027905 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,10758802 0,13019351 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,10758802 0,13010808 ! response to temperature stimulus GO:0009266 30 30 0,000 0,10758802 0,13002276 ! regulation of ossification GO:0030278 30 30 0,000 0,10758802 0,12993756 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,10758802 0,12985247 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,10758802 0,12976748 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,10758802 0,12968261 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,10758802 0,12959785 ! vesicle organization GO:0016050 30 30 0,000 0,10758802 0,1295132 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,10758802 0,12942867 ! establishment of organelle localization GO:0051656 31 30 0,000 0,10758802 0,12934424 ! regulation of translational initiation GO:0006446 31 31 0,000 0,11097527 0,13332949 ! membrane fusion GO:0006944 31 31 0,000 0,11097527 0,13324263 ! B cell activation GO:0042113 31 31 0,000 0,11097527 0,13315588 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,11097527 0,13306925 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,11097527 0,13298272 ! ion transmembrane transport GO:0034220 31 31 0,000 0,11097527 0,13289632 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,11097527 0,13281002 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,11097527 0,13272384 ! digestion GO:0007586 31 31 0,000 0,11097527 0,13263776 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,11097527 0,1325518 ! regulation of DNA replication GO:0006275 32 31 0,000 0,11097527 0,13246595 ! regulation of heart contraction GO:0008016 31 31 0,000 0,11097527 0,13238021 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,11097527 0,13229459 ! camera-type eye development GO:0043010 31 31 0,000 0,11097527 0,13220907 ! extracellular matrix organization GO:0030198 31 31 0,000 0,11097527 0,13212366 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,11097527 0,13203837 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,11097527 0,13195318 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,11097527 0,1318681 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,11097527 0,13178314 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,11435017 0,13570339 ! cell redox homeostasis GO:0045454 32 32 0,000 0,11435017 0,13561606 ! lipid modification GO:0030258 32 32 0,000 0,11435017 0,13552885 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,11435017 0,13544175 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,11435017 0,13535476 ! cell maturation GO:0048469 32 32 0,000 0,11435017 0,13526788 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,11435017 0,13518111 ! nuclear export GO:0051168 32 32 0,000 0,11435017 0,13509446 ! kidney development GO:0001822 32 32 0,000 0,11435017 0,13500792 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,11435017 0,13492148 ! negative regulation of cell size GO:0045792 33 33 0,000 0,11771274 0,13880011 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,11771274 0,13871137 ! amino acid transport GO:0006865 33 33 0,000 0,11771274 0,13862273 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,11771274 0,13853421 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,11771274 0,13844581 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,11771274 0,13835751 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,11771274 0,13826933 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,11771274 0,13818126 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,11771274 0,1380933 ! regulation of actin filament length GO:0030832 34 34 0,000 0,12106303 0,14193332 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,12106303 0,14184308 ! response to metal ion GO:0010038 34 34 0,000 0,12106303 0,14175297 ! ear development GO:0043583 34 34 0,000 0,12106303 0,14166297 ! muscle cell differentiation GO:0042692 35 34 0,000 0,12106303 0,14157308 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,12106303 0,14148331 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,12106303 0,14139365 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,12106303 0,1413041 ! secondary metabolic process GO:0019748 34 34 0,000 0,12106303 0,14121467 ! response to peptide hormone stimulus GO:0043434 36 34 0,000 0,12106303 0,14112535 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,12106303 0,14103614 ! viral reproduction GO:0016032 34 34 0,000 0,12106303 0,14094705 ! detection of stimulus GO:0051606 36 34 0,000 0,12106303 0,14085806 ! acute inflammatory response GO:0002526 35 35 0,000 0,12440109 0,14465061 ! regulation of cellular component size GO:0032535 35 35 0,000 0,12440109 0,14455941 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,12440109 0,14446832 ! mesoderm development GO:0007498 35 35 0,000 0,12440109 0,14437734 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,12440109 0,14428648 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,12440109 0,14419573 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,12440109 0,1441051 ! inorganic anion transport GO:0015698 35 35 0,000 0,12440109 0,14401458 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,12440109 0,14392418 ! regulation of immune effector process GO:0002697 35 35 0,000 0,12440109 0,14383389 ! hydrogen transport GO:0006818 36 36 0,000 0,12772696 0,1475867 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,12772696 0,14749423 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,12772696 0,14740187 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,12772696 0,14730963 ! regulation of mitosis GO:0007088 37 36 0,000 0,12772696 0,14721751 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,12772696 0,1471255 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,12772696 0,1470336 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,12772696 0,14694182 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,12772696 0,14685015 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,12772696 0,1467586 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,12772696 0,14666716 ! gonad development GO:0008406 36 36 0,000 0,12772696 0,14657584 ! activation of immune response GO:0002253 36 36 0,000 0,12772696 0,14648463 ! coagulation GO:0050817 39 36 0,000 0,12772696 0,14639353 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,13104068 0,15009818 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! response to drug GO:0042493 37 37 0,000 0,13104068 0,15000496 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,13104068 0,14991184 ! eye development GO:0001654 37 37 0,000 0,13104068 0,14981885 ! negative regulation of growth GO:0045926 37 37 0,000 0,13104068 0,14972596 ! DNA damage response, signal transduction GO:0042770 37 37 0,000 0,13104068 0,1496332 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,13104068 0,14954054 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,13104068 0,14944801 ! adaptive immune response GO:0002250 37 37 0,000 0,13104068 0,14935558 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,1343423 0,15302401 ! neurotransmitter transport GO:0006836 40 38 0,000 0,1343423 0,1529295 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,1343423 0,15283509 ! exocytosis GO:0006887 40 38 0,000 0,1343423 0,15274081 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,1343423 0,15264664 ! chromosome segregation GO:0007059 38 38 0,000 0,1343423 0,15255259 ! urogenital system development GO:0001655 38 38 0,000 0,1343423 0,15245865 ! RNA elongation GO:0006354 38 38 0,000 0,1343423 0,15236483 ! regulation of neurological system process GO:0031644 38 38 0,000 0,1343423 0,15227113 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,1343423 0,15217754 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,13763185 0,15580804 ! hemostasis GO:0007599 42 39 0,000 0,13763185 0,1557124 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,13763185 0,15561687 ! activation of MAPK activity GO:0000187 39 39 0,000 0,13763185 0,15552146 ! response to unfolded protein GO:0006986 39 39 0,000 0,13763185 0,15542616 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,13763185 0,15533098 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,13763185 0,15523592 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,13763185 0,15514097 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,13763185 0,15504615 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,13763185 0,15495143 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,13763185 0,15485683 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,13763185 0,15476235 ! developmental maturation GO:0021700 39 39 0,000 0,13763185 0,15466798 ! limb development GO:0060173 39 39 0,000 0,13763185 0,15457373 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,14090938 0,15815833 ! DNA catabolic process GO:0006308 41 40 0,000 0,14090938 0,15806207 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,14090938 0,15796592 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,14417492 0,1615285 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 0,000 0,14417492 0,16143037 ! amine catabolic process GO:0009310 42 41 0,000 0,14417492 0,16133235 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,14417492 0,16123446 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,14417492 0,16113668 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,14417492 0,16103902 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,14417492 0,16094148 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,14742854 0,16447385 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,14742854 0,16437435 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,14742854 0,16427497 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,14742854 0,16417571 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,14742854 0,16407657 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,14742854 0,16397755 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 0,000 0,14742854 0,16387864 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,14742854 0,16377986 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,14742854 0,1636812 ! reproductive structure development GO:0048608 43 43 0,000 0,15067025 0,16717958 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,15067025 0,16707899 ! mitochondrion organization GO:0007005 44 43 0,000 0,15067025 0,16697852 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,15067025 0,16687817 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,15067025 0,16677794 ! humoral immune response GO:0006959 44 44 0,000 0,15390012 0,17025085 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,15390012 0,17014872 ! mRNA transport GO:0051028 44 44 0,000 0,15390012 0,17004671 ! protein import into nucleus GO:0006606 44 44 0,000 0,15390012 0,16994483 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,15390012 0,16984306 ! vitamin metabolic process GO:0006766 44 44 0,000 0,15390012 0,16974142 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,15390012 0,1696399 ! amine biosynthetic process GO:0009309 46 45 0,000 0,15711817 0,17308355 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,15711817 0,17298016 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,15711817 0,17287688 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,15711817 0,17277374 ! nuclear import GO:0051170 45 45 0,000 0,15711817 0,17267071 ! protein processing GO:0016485 45 45 0,000 0,15711817 0,17256781 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,16032445 0,17598449 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,16032445 0,17587974 ! tube morphogenesis GO:0035239 47 46 0,000 0,16032445 0,17577511 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,16032445 0,1756706 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,16032445 0,17556623 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,16032445 0,17546197 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,16032445 0,17535784 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,163519 0,17874586 ! regulation of blood pressure GO:0008217 48 47 0,000 0,163519 0,1786399 ! sex differentiation GO:0007548 47 47 0,000 0,163519 0,17853407 ! amine transport GO:0015837 47 47 0,000 0,163519 0,17842837 ! rhythmic process GO:0048511 47 47 0,000 0,163519 0,17832279 ! calcium ion transport GO:0006816 48 48 0,000 0,16670186 0,1816863 ! actin filament organization GO:0007015 50 48 0,000 0,16670186 0,18157892 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,16670186 0,18147167 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,16670186 0,18136454 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,16670186 0,18125754 ! protein localization in nucleus GO:0034504 48 48 0,000 0,16670186 0,18115067 ! DNA recombination GO:0006310 48 48 0,000 0,16670186 0,18104392 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,16987308 0,18437932 ! divalent metal ion transport GO:0070838 49 49 0,000 0,16987308 0,1842708 ! response to nutrient GO:0007584 49 49 0,000 0,16987308 0,1841624 ! response to bacterium GO:0009617 50 49 0,000 0,16987308 0,18405414 ! regulation of ligase activity GO:0051340 50 49 0,000 0,16987308 0,183946 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,16987308 0,18383798 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,16987308 0,1837301 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,17303269 0,18703768 ! regulation of DNA metabolic process GO:0051052 51 50 0,000 0,17303269 0,18692805 ! chromatin assembly GO:0031497 50 50 0,000 0,17303269 0,18681854 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,17303269 0,18670916 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,17303269 0,18659991 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,17303269 0,18649079 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,17303269 0,18638179 ! transcription initiation GO:0006352 50 50 0,000 0,17303269 0,18627292 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,17618074 0,18955114 ! positive regulation of immune response GO:0050778 51 51 0,000 0,17618074 0,18944055 ! rRNA metabolic process GO:0016072 51 51 0,000 0,17618074 0,18933008 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,17618074 0,18921975 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,17618074 0,18910955 ! protein maturation GO:0051604 51 51 0,000 0,17618074 0,18899947 ! RNA localization GO:0006403 52 52 0,000 0,17931726 0,1922523 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,17931726 0,19214052 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,17931726 0,19202888 ! cell fate commitment GO:0045165 52 52 0,000 0,17931726 0,19191737 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,17931726 0,19180598 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,17931726 0,19169472 ! sodium ion transport GO:0006814 53 53 0,000 0,18244229 0,1949224 ! tRNA metabolic process GO:0006399 53 53 0,000 0,18244229 0,19480947 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,18244229 0,19469667 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,18244229 0,194584 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,18555589 0,19779034 ! response to virus GO:0009615 54 54 0,000 0,18555589 0,19767601 ! hormone metabolic process GO:0042445 55 54 0,000 0,18555589 0,19756181 ! sulfur metabolic process GO:0006790 55 54 0,000 0,18555589 0,19744775 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,18555589 0,19733381 ! nucleosome organization GO:0034728 55 55 0,000 0,18865808 0,2005172 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,18865808 0,20040163 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! in utero embryonic development GO:0001701 55 55 0,000 0,18865808 0,20028619 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,1917489 0,20345033 ! reproductive developmental process GO:0003006 56 56 0,000 0,1917489 0,20333327 ! regulation of nervous system development GO:0051960 57 56 0,000 0,1917489 0,20321635 ! ATP metabolic process GO:0046034 57 57 0,000 0,1948284 0,20636135 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,1948284 0,20624282 ! innate immune response GO:0045087 58 58 0,000 0,19789662 0,20937054 ! dephosphorylation GO:0016311 60 59 0,000 0,2009536 0,21248278 ! carboxylic acid transport GO:0046942 59 59 0,000 0,2009536 0,21236094 GO:0015849|organic acid transport, ! regulation of cell development GO:0060284 60 59 0,000 0,2009536 0,21223925 ! sterol metabolic process GO:0016125 59 59 0,000 0,2009536 0,21211769 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,2009536 0,21199627 ! protein localization in organelle GO:0033365 59 59 0,000 0,2009536 0,21187499 ! immune effector process GO:0002252 59 59 0,000 0,2009536 0,21175385 ! potassium ion transport GO:0006813 60 60 0,000 0,20399937 0,21484048 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,20399937 0,21471779 ! protein polymerization GO:0051258 65 60 0,000 0,20399937 0,21459523 ! cellular respiration GO:0045333 62 61 0,000 0,20703398 0,21766322 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,20703398 0,21753912 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,20703398 0,21741517 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,20703398 0,21729136 ! lipid transport GO:0006869 62 62 0,000 0,21005746 0,22033916 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,21005746 0,22021382 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,21005746 0,22008863 GO:0060429|epithelium development, ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,21005746 0,21996358 ! protein import GO:0017038 62 62 0,000 0,21005746 0,21983867 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,21005746 0,2197139 ! regulation of secretion GO:0051046 65 63 0,000 0,21306985 0,22273837 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,21306985 0,2226121 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,21306985 0,22248597 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,21306985 0,22235999 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,2160712 0,22536459 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,2160712 0,22523712 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,2160712 0,22510979 ! anion transport GO:0006820 65 65 0,000 0,21906154 0,22809628 ! positive regulation of cellular component organization GO:0051130 65 65 0,000 0,21906154 0,22796749 ! regulation of hormone levels GO:0010817 66 65 0,000 0,21906154 0,22783884 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,22204091 0,23080733 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,22204091 0,23067722 ! DNA packaging GO:0006323 66 66 0,000 0,22204091 0,23054726 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,22204091 0,23041745 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,22500935 0,23336647 ! muscle contraction GO:0006936 67 67 0,000 0,22500935 0,23323522 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,22500935 0,23310412 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,22500935 0,23297316 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,22796689 0,23590285 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,22796689 0,23577047 ! regulation of cell size GO:0008361 68 68 0,000 0,22796689 0,23563824 ! regulation of translation GO:0006417 69 69 0,000 0,23091358 0,2385503 ! sensory perception of sound GO:0007605 71 69 0,000 0,23091358 0,23841666 GO:0050954|sensory perception of mechanical stimulus, ! response to nutrient levels GO:0031667 69 69 0,000 0,23091358 0,23828317 ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,23091358 0,23814982 ! growth GO:0040007 70 70 0,000 0,23384946 0,24104281 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,23384946 0,24090808 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,23677456 0,2437852 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,23677456 0,24364908 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,23677456 0,24351312 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,23677456 0,2433773 ! negative regulation of signal transduction GO:0009968 71 71 0,000 0,23677456 0,24324164 ! secretion by cell GO:0032940 75 72 0,000 0,23968891 0,24609842 ! muscle system process GO:0003012 72 72 0,000 0,23968891 0,2459614 ! sensory organ development GO:0007423 72 72 0,000 0,23968891 0,24582452 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,23968891 0,2456878 ! regulation of cytokine production GO:0001817 72 72 0,000 0,23968891 0,24555123 ! electron transport chain GO:0022900 75 74 0,000 0,24548556 0,25134994 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,24548556 0,25121038 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,24836793 0,25401892 ! response to oxidative stress GO:0006979 76 75 0,000 0,24836793 0,25387803 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,24836793 0,2537373 ! negative regulation of cell communication GO:0010648 76 76 0,000 0,2512397 0,25652896 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,2512397 0,25638692 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,25410093 0,25916326 ! microtubule-based movement GO:0007018 82 78 0,000 0,25695163 0,26192581 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,25695163 0,26178102 ! metal ion homeostasis GO:0055065 78 78 0,000 0,25695163 0,26163639 ! regulation of immune response GO:0050776 78 78 0,000 0,25695163 0,26149192 ! nuclear transport GO:0051169 79 79 0,000 0,25979187 0,26423643 GO:0006913|nucleocytoplasmic transport, ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,26262166 0,2669673 ! lipid catabolic process GO:0016042 82 81 0,000 0,26544105 0,26968459 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,27104876 0,27523023 ! ncRNA processing GO:0034470 83 83 0,000 0,27104876 0,27507867 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,27383715 0,27775557 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,27661529 0,28041913 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,27661529 0,28026497 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,27661529 0,28011098 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,27938321 0,28275852 GO:0006644|phospholipid metabolic process, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,28488853 0,28817209 ! chemotaxis GO:0006935 90 89 0,000 0,287626 0,29078152 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,287626 0,2906221 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,29307074 0,2959613 ! DNA replication GO:0006260 91 91 0,000 0,29307074 0,29579922 ! visual perception GO:0007601 93 92 0,000 0,29577809 0,29836837 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,29577809 0,29820515 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,29577809 0,29804211 ! tissue morphogenesis GO:0048729 94 93 0,000 0,29847546 0,30059578 ! regulation of response to stress GO:0080134 97 94 0,000 0,3011629 0,30313666 ! epidermis development GO:0008544 94 94 0,000 0,3011629 0,30297119 ! cofactor metabolic process GO:0051186 95 94 0,000 0,3011629 0,3028059 ! regulation of cell growth GO:0001558 97 96 0,000 0,3065081 0,30801223 ! endocytosis GO:0006897 99 98 0,000 0,31181399 0,3131734 GO:0010324|membrane invagination, ! posttranscriptional regulation of gene expression GO:0010608 98 98 0,000 0,31181399 0,31300282 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,31181399 0,31283243 ! blood circulation GO:0008015 99 98 0,000 0,31181399 0,31266223 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,31181399 0,31249221 ! anti-apoptosis GO:0006916 100 99 0,000 0,31445227 0,31496497 ! ectoderm development GO:0007398 99 99 0,000 0,31445227 0,31479388 ! response to hormone stimulus GO:0009725 102 100 0,000 0,31708083 0,31725297 ! response to other organism GO:0051707 101 100 0,000 0,31708083 0,31708083