pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6460-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! T cell lineage commitment GO:0002360 5 5 2,000 4,781E-06 8,811E-03 ! peptidyl-amino acid modification GO:0018193 61 59 5,000 6,423E-06 5,918E-03 ! cell junction assembly GO:0034329 18 17 3,000 8,055E-06 4,948E-03 ! focal adhesion formation GO:0048041 7 6 2,000 9,508E-06 4,381E-03 ! regulation of embryonic development GO:0045995 6 6 2,000 9,508E-06 3,505E-03 ! response to gamma radiation GO:0010332 8 7 2,000 1,654E-05 5,082E-03 ! cell junction organization GO:0034330 23 22 3,000 2,403E-05 6,327E-03 ! fructose metabolic process GO:0006000 8 8 2,000 2,632E-05 6,064E-03 ! release of cytochrome c from mitochondria GO:0001836 9 8 2,000 2,632E-05 5,39E-03 ! positive regulation of growth GO:0045927 23 23 3,000 2,892E-05 5,33E-03 ! regulation of catabolic process GO:0009894 48 47 4,000 3,224E-05 5,401E-03 ! epithelial tube morphogenesis GO:0060562 25 24 3,000 3,45E-05 5,298E-03 ! response to ethanol GO:0045471 9 9 2,000 3,926E-05 5,566E-03 ! cell cycle arrest GO:0007050 49 49 4,000 3,959E-05 5,212E-03 ! apoptotic mitochondrial changes GO:0008637 11 10 2,000 5,577E-05 6,852E-03 ! cell-substrate junction assembly GO:0007044 11 10 2,000 5,577E-05 6,423E-03 ! intermediate filament cytoskeleton organization GO:0045104 10 10 2,000 5,577E-05 6,046E-03 ! intermediate filament-based process GO:0045103 11 11 2,000 7,624E-05 7,806E-03 ! positive regulation of multicellular organism growth GO:0040018 12 12 2,000 1,011E-04 9,805E-03 ! neural tube closure GO:0001843 13 12 2,000 1,011E-04 9,315E-03 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! mitochondrial membrane organization GO:0007006 13 13 2,000 1,307E-04 0,01146724 ! actin filament bundle formation GO:0051017 13 13 2,000 1,307E-04 0,010946 ! negative regulation of protein catabolic process GO:0042177 13 13 2,000 1,307E-04 0,01047009 ! cell aging GO:0007569 13 13 2,000 1,307E-04 0,01003383 ! tissue homeostasis GO:0001894 13 13 2,000 1,307E-04 9,632E-03 GO:0048871|multicellular organismal homeostasis, ! protein tetramerization GO:0051262 13 13 2,000 1,307E-04 9,262E-03 ! response to hormone stimulus GO:0009725 102 100 5,000 1,322E-04 9,023E-03 ! regulation of protein catabolic process GO:0042176 35 34 3,000 1,419E-04 9,34E-03 ! response to peptide hormone stimulus GO:0043434 36 34 3,000 1,419E-04 9,018E-03 ! primary neural tube formation GO:0014020 15 14 2,000 1,654E-04 0,01015848 ! integrin-mediated signaling pathway GO:0007229 36 36 3,000 1,781E-04 0,01058858 ! response to drug GO:0042493 37 37 3,000 1,985E-04 0,0114331 ! insulin receptor signaling pathway GO:0008286 17 15 2,000 2,055E-04 0,01147846 ! response to ionizing radiation GO:0010212 16 15 2,000 2,055E-04 0,01114086 ! regulation of mitotic cell cycle GO:0007346 72 69 4,000 2,067E-04 0,01088413 ! cell-matrix adhesion GO:0007160 39 38 3,000 2,206E-04 0,01129128 ! activation of MAPK activity GO:0000187 39 39 3,000 2,443E-04 0,01216936 ! protein oligomerization GO:0051259 39 39 3,000 2,443E-04 0,01184911 ! positive regulation of cell motion GO:0051272 39 39 3,000 2,443E-04 0,01154529 ! regulation of synaptic plasticity GO:0048167 16 16 2,000 2,515E-04 0,01158917 ! lymphocyte proliferation GO:0046651 16 16 2,000 2,515E-04 0,0113065 ! embryonic epithelial tube formation GO:0001838 17 16 2,000 2,515E-04 0,0110373 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 2,000 2,515E-04 0,01078062 ! cell-substrate adhesion GO:0031589 43 42 3,000 3,266E-04 0,01368063 ! mononuclear cell proliferation GO:0032943 18 18 2,000 3,624E-04 0,01484157 GO:0070661|leukocyte proliferation, ! B cell differentiation GO:0030183 18 18 2,000 3,624E-04 0,01451893 ! negative regulation of catabolic process GO:0009895 18 18 2,000 3,624E-04 0,01421002 ! positive regulation of protein kinase cascade GO:0010740 79 78 4,000 3,677E-04 0,01411752 ! regulation of cell motion GO:0051270 79 79 4,000 3,902E-04 0,01467475 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 2,000 4,279E-04 0,01577234 ! tube development GO:0035295 83 81 4,000 4,382E-04 0,01583582 ! tube morphogenesis GO:0035239 47 46 3,000 4,65E-04 0,01648187 ! cellular response to hormone stimulus GO:0032870 48 46 3,000 4,65E-04 0,01617089 ! neural tube development GO:0021915 21 20 2,000 5,006E-04 0,01708418 ! peptidyl-tyrosine modification GO:0018212 21 20 2,000 5,006E-04 0,01677356 ! actin filament organization GO:0007015 50 48 3,000 5,48E-04 0,01803435 ! morphogenesis of embryonic epithelium GO:0016331 22 21 2,000 5,807E-04 0,01877592 ! regulation of multicellular organism growth GO:0040014 21 21 2,000 5,807E-04 0,0184522 ! cellular response to insulin stimulus GO:0032869 23 21 2,000 5,807E-04 0,01813945 ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 5,932E-04 0,01822015 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 6,179E-04 0,01866945 ! prostate gland development GO:0030850 5 5 1,000 6,179E-04 0,01836833 ! metencephalon development GO:0022037 5 5 1,000 6,179E-04 0,01807677 ! 2-oxoglutarate metabolic process GO:0006103 5 5 1,000 6,179E-04 0,01779432 ! memory GO:0007613 5 5 1,000 6,179E-04 0,01752056 ! amyloid precursor protein catabolic process GO:0042987 5 5 1,000 6,179E-04 0,01725509 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 1,000 6,179E-04 0,01699756 ! indolalkylamine metabolic process GO:0006586 5 5 1,000 6,179E-04 0,01674759 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! fear response GO:0042596 5 5 1,000 6,179E-04 0,01650487 ! protein heterooligomerization GO:0051291 5 5 1,000 6,179E-04 0,01626909 ! response to UV-B GO:0010224 5 5 1,000 6,179E-04 0,01603995 ! response to amine stimulus GO:0014075 5 5 1,000 6,179E-04 0,01581717 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of mitochondrial membrane potential GO:0051881 5 5 1,000 6,179E-04 0,0156005 ! cellular pigmentation GO:0033059 5 5 1,000 6,179E-04 0,01538968 ! histone methylation GO:0016571 5 5 1,000 6,179E-04 0,01518448 ! peptidyl-lysine modification GO:0018205 5 5 1,000 6,179E-04 0,01498469 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 6,179E-04 0,01479008 ! peptidyl-histidine modification GO:0018202 5 5 1,000 6,179E-04 0,01460046 ! oocyte differentiation GO:0009994 5 5 1,000 6,179E-04 0,01441565 GO:0048599|oocyte development, ! regulation of protein homodimerization activity GO:0043496 6 5 1,000 6,179E-04 0,01423545 ! spleen development GO:0048536 5 5 1,000 6,179E-04 0,01405971 ! response to nicotine GO:0035094 5 5 1,000 6,179E-04 0,01388825 ! T cell activation GO:0042110 51 50 3,000 6,409E-04 0,01423209 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 3,000 6,409E-04 0,01406266 ! regulation of neurogenesis GO:0050767 51 50 3,000 6,409E-04 0,01389722 ! anatomical structure homeostasis GO:0060249 51 50 3,000 6,409E-04 0,01373562 ! positive regulation of transcription factor activity GO:0051091 22 22 2,000 6,686E-04 0,01416342 GO:0090047|positive regulation of transcription regulator activity, ! protein modification by small protein conjugation GO:0032446 52 51 3,000 6,914E-04 0,01447999 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 3,000 7,446E-04 0,01541896 ! response to light stimulus GO:0009416 53 52 3,000 7,446E-04 0,01524764 ! response to hypoxia GO:0001666 53 53 3,000 8,006E-04 0,01621497 ! response to oxygen levels GO:0070482 55 54 3,000 8,596E-04 0,01721973 ! mitochondrial transport GO:0006839 24 24 2,000 8,688E-04 0,01721791 ! T cell differentiation GO:0030217 24 24 2,000 8,688E-04 0,01703474 ! androgen receptor signaling pathway GO:0030521 24 24 2,000 8,688E-04 0,01685543 ! glucan metabolic process GO:0044042 25 24 2,000 8,688E-04 0,01667985 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! protein modification by small protein conjugation or removal GO:0070647 56 55 3,000 9,215E-04 0,01750928 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 1,000 9,221E-04 0,01734177 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 9,221E-04 0,0171666 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 9,221E-04 0,01699493 ! succinate metabolic process GO:0006105 7 6 1,000 9,221E-04 0,01682666 ! ER overload response GO:0006983 6 6 1,000 9,221E-04 0,0166617 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 9,221E-04 0,01649993 ! negative regulation of ossification GO:0030279 6 6 1,000 9,221E-04 0,01634128 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 9,221E-04 0,01618565 ! protein sumoylation GO:0016925 6 6 1,000 9,221E-04 0,01603295 ! thymus development GO:0048538 6 6 1,000 9,221E-04 0,01588311 ! negative regulation of BMP signaling pathway GO:0030514 6 6 1,000 9,221E-04 0,01573605 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 9,221E-04 0,01559168 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of cell growth GO:0001558 97 96 4,000 9,548E-04 0,01599663 ! regulation of gene-specific transcription GO:0032583 25 25 2,000 9,817E-04 0,01630054 ! positive regulation of DNA binding GO:0043388 26 25 2,000 9,817E-04 0,016155 ! reproductive developmental process GO:0003006 56 56 3,000 9,866E-04 0,01609089 ! regulation of nervous system development GO:0051960 57 56 3,000 9,866E-04 0,01594974 ! regulation of binding GO:0051098 60 57 3,000 1,055E-03 0,01690417 ! positive regulation of binding GO:0051099 27 26 2,000 1,104E-03 0,01753304 ! glycolysis GO:0006096 26 26 2,000 1,104E-03 0,01738319 ! response to insulin stimulus GO:0032868 28 26 2,000 1,104E-03 0,01723587 ! regulation of cell development GO:0060284 60 59 3,000 1,201E-03 0,01860106 ! energy reserve metabolic process GO:0006112 28 27 2,000 1,234E-03 0,01895973 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 1,000 1,284E-03 0,01956276 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 1,000 1,284E-03 0,01940241 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 1,284E-03 0,01924466 ! hair follicle morphogenesis GO:0031069 7 7 1,000 1,284E-03 0,01908947 ! oxaloacetate metabolic process GO:0006107 7 7 1,000 1,284E-03 0,01893675 ! visual behavior GO:0007632 7 7 1,000 1,284E-03 0,01878646 GO:0008542|visual learning, ! startle response GO:0001964 7 7 1,000 1,284E-03 0,01863853 ! amyloid precursor protein metabolic process GO:0042982 7 7 1,000 1,284E-03 0,01849292 ! digestive system development GO:0055123 7 7 1,000 1,284E-03 0,01834956 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! regulation of mRNA processing GO:0050684 7 7 1,000 1,284E-03 0,01820841 ! membrane protein ectodomain proteolysis GO:0006509 7 7 1,000 1,284E-03 0,01806942 GO:0033619|membrane protein proteolysis, ! regulation of skeletal muscle fiber development GO:0048742 7 7 1,000 1,284E-03 0,01793253 ! response to X-ray GO:0010165 7 7 1,000 1,284E-03 0,0177977 ! regulation of intracellular pH GO:0051453 7 7 1,000 1,284E-03 0,01766488 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 1,284E-03 0,01753403 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! alpha-beta T cell differentiation GO:0046632 7 7 1,000 1,284E-03 0,0174051 ! axon cargo transport GO:0008088 7 7 1,000 1,284E-03 0,01727806 ! dopamine metabolic process GO:0042417 7 7 1,000 1,284E-03 0,01715285 ! histone modification GO:0016570 28 28 2,000 1,375E-03 0,018229 ! protein amino acid autophosphorylation GO:0046777 28 28 2,000 1,375E-03 0,01809879 ! morphogenesis of an epithelium GO:0002009 63 62 3,000 1,446E-03 0,01890404 GO:0060429|epithelium development, ! covalent chromatin modification GO:0016569 29 29 2,000 1,525E-03 0,01979068 ! response to UV GO:0009411 29 29 2,000 1,525E-03 0,01965229 ! glucose metabolic process GO:0006006 63 63 3,000 1,535E-03 0,01964881 ! regulation of skeletal muscle tissue development GO:0048641 8 8 1,000 1,704E-03 0,02165486 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 1,704E-03 0,02150654 ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 1,000 1,704E-03 0,02136024 ! T cell selection GO:0045058 8 8 1,000 1,704E-03 0,02121591 ! negative regulation of proteolysis GO:0045861 8 8 1,000 1,704E-03 0,02107352 ! phosphagen metabolic process GO:0006599 8 8 1,000 1,704E-03 0,02093303 GO:0006600|creatine metabolic process, ! cell-cell junction assembly GO:0007043 8 8 1,000 1,704E-03 0,0207944 ! sex determination GO:0007530 8 8 1,000 1,704E-03 0,0206576 ! negative regulation of mitotic cell cycle GO:0045930 9 8 1,000 1,704E-03 0,02052258 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 1,704E-03 0,02038932 ! alpha-beta T cell activation GO:0046631 8 8 1,000 1,704E-03 0,02025778 ! gastrulation with mouth forming second GO:0001702 8 8 1,000 1,704E-03 0,02012792 ! T cell homeostasis GO:0043029 8 8 1,000 1,704E-03 0,01999971 ! peptidyl-serine modification GO:0018209 8 8 1,000 1,704E-03 0,01987313 ! branched chain family amino acid metabolic process GO:0009081 8 8 1,000 1,704E-03 0,01974815 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 1,704E-03 0,01962472 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 1,825E-03 0,02089052 ! B cell activation GO:0042113 31 31 2,000 1,855E-03 0,02110043 ! aging GO:0007568 32 31 2,000 1,855E-03 0,02097097 ! regulation of DNA replication GO:0006275 32 31 2,000 1,855E-03 0,0208431 ! negative regulation of cell motion GO:0051271 31 31 2,000 1,855E-03 0,02071678 ! glucose catabolic process GO:0006007 32 32 2,000 2,035E-03 0,02259431 ! negative regulation of cell growth GO:0030308 32 32 2,000 2,035E-03 0,02245902 ! response to radiation GO:0009314 70 68 3,000 2,038E-03 0,0223566 ! regulation of cell size GO:0008361 68 68 3,000 2,038E-03 0,02222431 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 1,000 2,179E-03 0,02362596 ! regulation of postsynaptic membrane potential GO:0060078 9 9 1,000 2,179E-03 0,0234878 ! response to alkaloid GO:0043279 10 9 1,000 2,179E-03 0,02335124 ! activation of pro-apoptotic gene products GO:0008633 9 9 1,000 2,179E-03 0,02321626 ! response to osmotic stress GO:0006970 9 9 1,000 2,179E-03 0,02308283 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 1,000 2,179E-03 0,02295093 GO:0060675|ureteric bud morphogenesis, ! prostaglandin metabolic process GO:0006693 9 9 1,000 2,179E-03 0,02282053 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 1,000 2,179E-03 0,0226916 ! regulation of cellular pH GO:0030641 9 9 1,000 2,179E-03 0,02256412 ! histone acetylation GO:0016573 9 9 1,000 2,179E-03 0,02243806 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 2,179E-03 0,02231341 ! defense response to virus GO:0051607 9 9 1,000 2,179E-03 0,02219013 ! regulation of neuron differentiation GO:0045664 34 33 2,000 2,226E-03 0,02254126 ! regulation of neuron apoptosis GO:0043523 34 33 2,000 2,226E-03 0,02241809 ! regulation of synaptic transmission GO:0050804 33 33 2,000 2,226E-03 0,02229625 ! negative regulation of cell size GO:0045792 33 33 2,000 2,226E-03 0,02217573 ! regulation of cell migration GO:0030334 71 71 3,000 2,389E-03 0,02366974 ! cellular polysaccharide metabolic process GO:0044264 35 34 2,000 2,428E-03 0,02392631 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 2,71E-03 0,02656821 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 2,71E-03 0,02642763 ! epidermis morphogenesis GO:0048730 10 10 1,000 2,71E-03 0,02628854 ! regulation of protein binding GO:0043393 11 10 1,000 2,71E-03 0,0261509 ! gland morphogenesis GO:0022612 10 10 1,000 2,71E-03 0,0260147 ! regulation of BMP signaling pathway GO:0030510 10 10 1,000 2,71E-03 0,02587991 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 1,000 2,71E-03 0,02574651 ! lymphocyte homeostasis GO:0002260 10 10 1,000 2,71E-03 0,02561448 ! gut development GO:0048565 10 10 1,000 2,71E-03 0,02548379 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 2,71E-03 0,02535443 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 2,71E-03 0,02522638 ! regulation of mitosis GO:0007088 37 36 2,000 2,864E-03 0,02652613 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 36 36 2,000 2,864E-03 0,02639349 ! regulation of transmission of nerve impulse GO:0051969 36 36 2,000 2,864E-03 0,02626218 ! regulation of transcription factor activity GO:0051090 38 37 2,000 3,099E-03 0,02827814 GO:0090046|regulation of transcription regulator activity, ! negative regulation of protein kinase activity GO:0006469 37 37 2,000 3,099E-03 0,02813884 ! negative regulation of growth GO:0045926 37 37 2,000 3,099E-03 0,02800091 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 1,000 3,295E-03 0,02962711 ! microtubule-based transport GO:0010970 11 11 1,000 3,295E-03 0,02948329 ! protein amino acid methylation GO:0006479 11 11 1,000 3,295E-03 0,02934086 GO:0008213|protein amino acid alkylation, ! protein amino acid acetylation GO:0006473 11 11 1,000 3,295E-03 0,0291998 ! T cell proliferation GO:0042098 11 11 1,000 3,295E-03 0,02906008 ! regulation of transmembrane transporter activity GO:0022898 11 11 1,000 3,295E-03 0,0289217 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! regulation of viral genome replication GO:0045069 11 11 1,000 3,295E-03 0,02878463 ! cellular response to starvation GO:0009267 11 11 1,000 3,295E-03 0,02864886 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 3,295E-03 0,02851435 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 3,295E-03 0,02838111 ! G1/S transition checkpoint GO:0031575 12 11 1,000 3,295E-03 0,0282491 ! interaction with host GO:0051701 11 11 1,000 3,295E-03 0,02811832 ! membrane depolarization GO:0051899 11 11 1,000 3,295E-03 0,02798874 ! oogenesis GO:0048477 11 11 1,000 3,295E-03 0,02786036 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 3,295E-03 0,02773314 GO:0006109|regulation of carbohydrate metabolic process, ! muscle maintenance GO:0046716 12 11 1,000 3,295E-03 0,02760708 ! hindbrain development GO:0030902 11 11 1,000 3,295E-03 0,02748216 ! negative regulation of kinase activity GO:0033673 38 38 2,000 3,346E-03 0,02777909 ! urogenital system development GO:0001655 38 38 2,000 3,346E-03 0,02765452 ! hexose catabolic process GO:0019320 38 38 2,000 3,346E-03 0,02753107 ! regulation of neurological system process GO:0031644 38 38 2,000 3,346E-03 0,02740871 ! steroid hormone receptor signaling pathway GO:0030518 38 38 2,000 3,346E-03 0,02728743 ! regulation of locomotion GO:0040012 79 79 3,000 3,524E-03 0,02861047 ! lymphocyte differentiation GO:0030098 39 39 2,000 3,605E-03 0,0291375 ! MAPKKK cascade GO:0000165 82 81 3,000 3,856E-03 0,03103655 ! lymphocyte activation GO:0046649 82 81 3,000 3,856E-03 0,03090161 ! negative regulation of transferase activity GO:0051348 40 40 2,000 3,875E-03 0,03091634 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 2,000 3,875E-03 0,03078308 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 3,934E-03 0,03112022 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 1,000 3,934E-03 0,03098722 ! glutamate signaling pathway GO:0007215 12 12 1,000 3,934E-03 0,03085536 ! positive regulation of endocytosis GO:0045807 12 12 1,000 3,934E-03 0,03072462 ! glycoprotein catabolic process GO:0006516 13 12 1,000 3,934E-03 0,03059498 ! vesicle docking during exocytosis GO:0006904 12 12 1,000 3,934E-03 0,03046643 ! male gonad development GO:0008584 12 12 1,000 3,934E-03 0,03033896 ! renal system process GO:0003014 12 12 1,000 3,934E-03 0,03021254 ! somitogenesis GO:0001756 13 12 1,000 3,934E-03 0,03008718 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 1,000 3,934E-03 0,02996285 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 3,934E-03 0,02983955 ! monosaccharide catabolic process GO:0046365 41 41 2,000 4,157E-03 0,03140262 ! protein ubiquitination GO:0016567 43 42 2,000 4,452E-03 0,03349118 ! positive regulation of DNA replication GO:0045740 14 13 1,000 4,626E-03 0,03465688 ! phenol metabolic process GO:0018958 13 13 1,000 4,626E-03 0,03451657 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! positive regulation of JAK-STAT cascade GO:0046427 13 13 1,000 4,626E-03 0,03437739 ! regeneration GO:0031099 13 13 1,000 4,626E-03 0,03423932 ! post-embryonic development GO:0009791 14 13 1,000 4,626E-03 0,03410237 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 4,626E-03 0,0339665 ! negative regulation of DNA replication GO:0008156 13 13 1,000 4,626E-03 0,03383171 ! response to corticosteroid stimulus GO:0031960 13 13 1,000 4,626E-03 0,03369799 GO:0051384|response to glucocorticoid stimulus, ! ureteric bud development GO:0001657 13 13 1,000 4,626E-03 0,03356532 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 4,626E-03 0,03343369 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 4,626E-03 0,03330309 ! regulation of viral reproduction GO:0050792 13 13 1,000 4,626E-03 0,03317351 ! negative regulation of intracellular transport GO:0032387 13 13 1,000 4,626E-03 0,03304493 ! cell-cell junction organization GO:0045216 13 13 1,000 4,626E-03 0,03291734 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 4,626E-03 0,03279074 GO:0001952|regulation of cell-matrix adhesion, ! response to cytokine stimulus GO:0034097 13 13 1,000 4,626E-03 0,0326651 ! activation of JUN kinase activity GO:0007257 13 13 1,000 4,626E-03 0,03254043 ! reproductive structure development GO:0048608 43 43 2,000 4,759E-03 0,03335079 ! mitochondrion organization GO:0007005 44 43 2,000 4,759E-03 0,03322446 ! alcohol catabolic process GO:0046164 43 43 2,000 4,759E-03 0,03309908 ! positive regulation of protein kinase activity GO:0045860 89 86 3,000 4,78E-03 0,03311549 ! hexose metabolic process GO:0019318 87 86 3,000 4,78E-03 0,03299146 ! positive regulation of transferase activity GO:0051347 91 88 3,000 5,187E-03 0,03567106 GO:0033674|positive regulation of kinase activity, ! protein amino acid acylation GO:0043543 14 14 1,000 5,369E-03 0,03678711 ! vesicle docking GO:0048278 14 14 1,000 5,369E-03 0,03665086 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 1,000 5,369E-03 0,03651561 ! hair cycle GO:0042633 14 14 1,000 5,369E-03 0,03638137 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! multicellular organismal response to stress GO:0033555 14 14 1,000 5,369E-03 0,0362481 ! base-excision repair GO:0006284 14 14 1,000 5,369E-03 0,03611581 ! response to organic cyclic substance GO:0014070 15 14 1,000 5,369E-03 0,03598448 ! positive regulation of inflammatory response GO:0050729 14 14 1,000 5,369E-03 0,0358541 ! regulation of DNA binding GO:0051101 47 45 2,000 5,411E-03 0,03600228 ! regulation of membrane potential GO:0042391 46 46 2,000 5,756E-03 0,03816043 ! sex differentiation GO:0007548 47 47 2,000 6,114E-03 0,0403886 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 6,164E-03 0,04057099 ! ovarian follicle development GO:0001541 15 15 1,000 6,164E-03 0,04042661 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 6,164E-03 0,04028325 ! response to starvation GO:0042594 15 15 1,000 6,164E-03 0,04014091 ! leukocyte homeostasis GO:0001776 15 15 1,000 6,164E-03 0,03999956 ! tissue morphogenesis GO:0048729 94 93 3,000 6,307E-03 0,04078329 ! regulation of cell cycle process GO:0010564 50 48 2,000 6,485E-03 0,04179133 ! leukocyte differentiation GO:0002521 50 49 2,000 6,87E-03 0,04411332 ! gland development GO:0048732 51 49 2,000 6,87E-03 0,04396015 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 1,000 7,008E-03 0,04469374 ! learning GO:0007612 16 16 1,000 7,008E-03 0,04453963 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 7,008E-03 0,04438657 ! segmentation GO:0035282 17 16 1,000 7,008E-03 0,04423456 ! positive regulation of cell development GO:0010720 16 16 1,000 7,008E-03 0,04408359 ! cellular response to nutrient levels GO:0031669 16 16 1,000 7,008E-03 0,04393365 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 1,000 7,008E-03 0,04378472 ! regulation of JUN kinase activity GO:0043506 17 16 1,000 7,008E-03 0,0436368 GO:0043507|positive regulation of JUN kinase activity, ! regulation of DNA metabolic process GO:0051052 51 50 2,000 7,267E-03 0,04509509 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 7,902E-03 0,04887269 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 1,000 7,902E-03 0,04870924 ! regulation of transmembrane transport GO:0034762 17 17 1,000 7,902E-03 0,04854687 ! dicarboxylic acid metabolic process GO:0043648 18 17 1,000 7,902E-03 0,04838559 ! glucose transport GO:0015758 17 17 1,000 7,902E-03 0,04822537 ! development of primary male sexual characteristics GO:0046546 17 17 1,000 7,902E-03 0,04806621 ! response to toxin GO:0009636 18 17 1,000 7,902E-03 0,0479081 ! negative regulation of cell development GO:0010721 18 17 1,000 7,902E-03 0,04775102 GO:0050768|negative regulation of neurogenesis, ! pigmentation GO:0043473 17 17 1,000 7,902E-03 0,04759497 ! cell fate commitment GO:0045165 52 52 2,000 8,103E-03 0,04864179 ! carbohydrate catabolic process GO:0016052 53 53 2,000 8,541E-03 0,05110544 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 8,845E-03 0,05275432 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 8,845E-03 0,05258415 ! membrane docking GO:0022406 18 18 1,000 8,845E-03 0,05241507 ! hexose transport GO:0008645 18 18 1,000 8,845E-03 0,05224707 GO:0015749|monosaccharide transport, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 8,845E-03 0,05208014 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 8,845E-03 0,05191428 ! regulation of microtubule-based process GO:0032886 18 18 1,000 8,845E-03 0,05174948 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 8,845E-03 0,05158571 ! protein amino acid dephosphorylation GO:0006470 55 54 2,000 8,993E-03 0,05228138 ! microtubule cytoskeleton organization GO:0000226 55 55 2,000 9,458E-03 0,0548156 ! regulation of cell adhesion GO:0030155 56 55 2,000 9,458E-03 0,05464376 ! DNA damage checkpoint GO:0000077 19 19 1,000 9,835E-03 0,056644 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 9,835E-03 0,05646754 ! regulation of pH GO:0006885 19 19 1,000 9,835E-03 0,05629218 ! regulation of JAK-STAT cascade GO:0046425 19 19 1,000 9,835E-03 0,0561179 ! regulation of striated muscle tissue development GO:0016202 20 19 1,000 9,835E-03 0,0559447 ! multicellular organismal metabolic process GO:0044236 19 19 1,000 9,835E-03 0,05577256 ! metanephros development GO:0001656 19 19 1,000 9,835E-03 0,05560148 ! regulation of protein stability GO:0031647 19 19 1,000 9,835E-03 0,05543144 ! response to heat GO:0009408 19 19 1,000 9,835E-03 0,05526244 ! regulation of protein localization GO:0032880 58 57 2,000 0,01043116 0,05843352 ! regulation of muscle development GO:0048634 21 20 1,000 0,01087227 0,06071996 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 1,000 0,01087227 0,06053651 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 0,01087227 0,06035417 ! female gamete generation GO:0007292 20 20 1,000 0,01087227 0,06017293 ! negative regulation of neuron apoptosis GO:0043524 21 20 1,000 0,01087227 0,05999277 ! dephosphorylation GO:0016311 60 59 2,000 0,01146036 0,06304909 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 0,01195559 0,06557783 ! Notch signaling pathway GO:0007219 22 21 1,000 0,01195559 0,06538323 ! DNA integrity checkpoint GO:0031570 21 21 1,000 0,01195559 0,06518979 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 1,000 0,01195559 0,06499749 ! regulation of proteolysis GO:0030162 21 21 1,000 0,01195559 0,06480632 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 0,01195559 0,06461627 ! negative regulation of protein transport GO:0051224 21 21 1,000 0,01195559 0,06442734 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 2,000 0,01254631 0,06741353 ! ovulation cycle process GO:0022602 22 22 1,000 0,01308429 0,07009983 ! male sex differentiation GO:0046661 22 22 1,000 0,01308429 0,06989665 ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 0,01308429 0,06969463 ! cellular amide metabolic process GO:0043603 22 22 1,000 0,01308429 0,06949378 ! biopolymer methylation GO:0043414 22 22 1,000 0,01308429 0,06929409 GO:0032259|methylation, ! response to hydrogen peroxide GO:0042542 24 23 1,000 0,0142576 0,07529155 ! response to estrogen stimulus GO:0043627 23 23 1,000 0,0142576 0,07507643 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 0,0142576 0,07486254 ! female gonad development GO:0008585 23 23 1,000 0,0142576 0,07464986 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 0,0142576 0,07443839 ! regulation of JNK cascade GO:0046328 25 23 1,000 0,0142576 0,07422811 ! cell projection assembly GO:0030031 25 23 1,000 0,0142576 0,07401902 ! positive regulation of protein metabolic process GO:0051247 64 64 2,000 0,01428268 0,07394095 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 1,000 0,01547476 0,07988789 ! glucose homeostasis GO:0042593 24 24 1,000 0,01547476 0,07966474 GO:0033500|carbohydrate homeostasis, ! ovulation cycle GO:0042698 24 24 1,000 0,01547476 0,07944283 ! polysaccharide metabolic process GO:0005976 69 66 2,000 0,0155125 0,07941536 ! negative regulation of protein metabolic process GO:0051248 66 66 2,000 0,0155125 0,07919537 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 0,01673502 0,08520066 ! development of primary female sexual characteristics GO:0046545 25 25 1,000 0,01673502 0,08496595 GO:0046660|female sex differentiation, ! gastrulation GO:0007369 25 25 1,000 0,01673502 0,08473253 ! heart morphogenesis GO:0003007 25 25 1,000 0,01673502 0,08450038 ! icosanoid metabolic process GO:0006690 25 25 1,000 0,01673502 0,08426951 ! regulation of endocytosis GO:0030100 25 25 1,000 0,01673502 0,08403989 ! JAK-STAT cascade GO:0007259 26 25 1,000 0,01673502 0,08381152 ! response to nutrient levels GO:0031667 69 69 2,000 0,0174664 0,08723731 ! positive regulation of defense response GO:0031349 26 26 1,000 0,01803764 0,08984695 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 1,000 0,01803764 0,08960478 ! negative regulation of cell migration GO:0030336 26 26 1,000 0,01803764 0,08936391 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 0,01803764 0,08912433 ! double-strand break repair GO:0006302 27 26 1,000 0,01803764 0,08888602 ! germ cell development GO:0007281 27 26 1,000 0,01803764 0,088649 ! pigment metabolic process GO:0042440 26 26 1,000 0,01803764 0,08841323 ! growth GO:0040007 70 70 2,000 0,01814694 0,08871303 ! chloride transport GO:0006821 27 27 1,000 0,01938189 0,09449955 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 0,01938189 0,09425021 ! learning or memory GO:0007611 28 27 1,000 0,01938189 0,09400218 ! activation of caspase activity GO:0006919 27 27 1,000 0,01938189 0,09375546 ! mesenchymal cell development GO:0014031 29 27 1,000 0,01938189 0,09351003 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! cell growth GO:0016049 27 27 1,000 0,01938189 0,09326587 ! response to extracellular stimulus GO:0009991 72 72 2,000 0,01955205 0,09383967 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 1,000 0,02076705 0,09941215 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 1,000 0,02076705 0,0991546 ! carbohydrate transport GO:0008643 28 28 1,000 0,02076705 0,09889839 ! unsaturated fatty acid metabolic process GO:0033559 28 28 1,000 0,02076705 0,09864349 ! developmental growth GO:0048589 28 28 1,000 0,02076705 0,09838991 ! viral reproductive process GO:0022415 29 29 1,000 0,0221924 0,10487332 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 0,0221924 0,1046051 ! positive regulation of multicellular organismal process GO:0051240 76 76 2,000 0,02253884 0,10596703 ! response to reactive oxygen species GO:0000302 31 30 1,000 0,02365723 0,1109422 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,02365723 0,11066062 GO:0043280|positive regulation of caspase activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 0,02365723 0,11038046 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 1,000 0,02365723 0,11010173 ! response to temperature stimulus GO:0009266 30 30 1,000 0,02365723 0,10982439 ! regulation of ossification GO:0030278 30 30 1,000 0,02365723 0,10954845 ! regulation of inflammatory response GO:0050727 30 30 1,000 0,02365723 0,10927389 ! vesicle organization GO:0016050 30 30 1,000 0,02365723 0,10900071 ! regulation of protein modification process GO:0031399 79 78 2,000 0,02412066 0,1108588 ! microtubule-based movement GO:0007018 82 78 2,000 0,02412066 0,11058303 ! regulation of intracellular transport GO:0032386 31 31 1,000 0,02516086 0,11506565 ! regulation of vesicle-mediated transport GO:0060627 33 32 1,000 0,02670257 0,12181397 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,02670257 0,12151319 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 0,02670257 0,1212139 ! kidney development GO:0001822 32 32 1,000 0,02670257 0,12091608 ! protein maturation by peptide bond cleavage GO:0051605 32 32 1,000 0,02670257 0,12061971 ! regulation of cellular response to stress GO:0080135 35 33 1,000 0,02828171 0,12744056 ! amino acid transport GO:0006865 33 33 1,000 0,02828171 0,12712973 ! activation of protein kinase activity GO:0032147 35 33 1,000 0,02828171 0,12682041 ! cellular amino acid derivative metabolic process GO:0006575 87 84 2,000 0,02921975 0,13070872 ! regulation of bone remodeling GO:0046850 34 34 1,000 0,02989758 0,13341707 ! response to metal ion GO:0010038 34 34 1,000 0,02989758 0,1330948 ! ear development GO:0043583 34 34 1,000 0,02989758 0,13277409 ! secondary metabolic process GO:0019748 34 34 1,000 0,02989758 0,13245492 ! viral reproduction GO:0016032 34 34 1,000 0,02989758 0,13213729 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 0,03154954 0,13910478 ! multicellular organism reproduction GO:0032504 36 35 1,000 0,03154954 0,13877279 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,03154954 0,13844238 ! regulation of tissue remodeling GO:0034103 35 35 1,000 0,03154954 0,13811354 ! inorganic anion transport GO:0015698 35 35 1,000 0,03154954 0,13778625 ! response to steroid hormone stimulus GO:0048545 35 35 1,000 0,03154954 0,13746052 ! heart development GO:0007507 90 87 2,000 0,0319676 0,13895349 ! response to inorganic substance GO:0010035 36 36 1,000 0,03323691 0,14413089 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 1,000 0,03323691 0,14379255 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,03323691 0,1434558 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 1,000 0,03323691 0,14312063 ! gonad development GO:0008406 36 36 1,000 0,03323691 0,14278701 ! lung development GO:0030324 38 37 1,000 0,03495906 0,14983614 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,03495906 0,14948849 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 0,03495906 0,14914245 ! negative regulation of cell cycle GO:0045786 92 91 2,000 0,0358357 0,15252933 ! exocytosis GO:0006887 40 38 1,000 0,03671533 0,15591325 ! chromosome segregation GO:0007059 38 38 1,000 0,03671533 0,15555483 ! regulation of homeostatic process GO:0032844 38 38 1,000 0,03671533 0,15519805 ! fatty acid metabolic process GO:0006631 93 92 2,000 0,03683901 0,15536451 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 2,000 0,03683901 0,1550098 ! positive regulation of protein modification process GO:0031401 39 39 1,000 0,03850509 0,16165123 ! respiratory tube development GO:0030323 40 39 1,000 0,03850509 0,16128384 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,03850509 0,16091812 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,03850509 0,16055405 ! regulation of MAPKKK cascade GO:0043408 41 39 1,000 0,03850509 0,16019162 ! respiratory system development GO:0060541 40 39 1,000 0,03850509 0,15983083 ! regulation of response to stress GO:0080134 97 94 2,000 0,0388889 0,1610612 ! blood vessel development GO:0001568 95 94 2,000 0,0388889 0,16070008 ! epidermis development GO:0008544 94 94 2,000 0,0388889 0,16034057 ! rRNA transcription GO:0009303 5 5 0,000 0,03934821 0,16187219 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,03934821 0,16151168 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,03934821 0,16115276 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,03934821 0,16079544 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,03934821 0,1604397 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,03934821 0,16008553 ! reproductive cellular process GO:0048610 5 5 0,000 0,03934821 0,15973291 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,03934821 0,15938185 ! water transport GO:0006833 5 5 0,000 0,03934821 0,15903233 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,03934821 0,15868434 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,03934821 0,15833787 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,03934821 0,1579929 ! glycerol metabolic process GO:0006071 5 5 0,000 0,03934821 0,15764944 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,03934821 0,15730747 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,03934821 0,15696698 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,03934821 0,15662796 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,03934821 0,15629039 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,03934821 0,15595429 ! filopodium assembly GO:0046847 7 5 0,000 0,03934821 0,15561962 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,03934821 0,15528639 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,03934821 0,15495458 ! GTP metabolic process GO:0046039 5 5 0,000 0,03934821 0,15462419 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,03934821 0,1542952 ! mRNA stabilization GO:0048255 5 5 0,000 0,03934821 0,15396761 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,03934821 0,15364141 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,03934821 0,15331658 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,03934821 0,15299313 ! social behavior GO:0035176 5 5 0,000 0,03934821 0,15267104 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,03934821 0,1523503 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,03934821 0,15203091 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,03934821 0,15171285 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,03934821 0,15139612 ! response to lipid GO:0033993 5 5 0,000 0,03934821 0,15108072 ! erythrocyte maturation GO:0043249 5 5 0,000 0,03934821 0,15076662 ! hippocampus development GO:0021766 6 5 0,000 0,03934821 0,15045382 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,03934821 0,15014233 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,03934821 0,14983211 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,03934821 0,14952318 ! mechanosensory behavior GO:0007638 5 5 0,000 0,03934821 0,14921552 ! heart looping GO:0001947 5 5 0,000 0,03934821 0,14890912 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,03934821 0,14860398 ! response to interferon-gamma GO:0034341 5 5 0,000 0,03934821 0,14830009 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,03934821 0,14799744 ! endocrine pancreas development GO:0031018 5 5 0,000 0,03934821 0,14769601 ! pH reduction GO:0045851 5 5 0,000 0,03934821 0,14739582 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,03934821 0,14709684 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,03934821 0,14679908 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,03934821 0,14650251 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,03934821 0,14620714 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,03934821 0,14591296 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,03934821 0,14561997 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,03934821 0,14532814 ! adrenal gland development GO:0030325 5 5 0,000 0,03934821 0,14503749 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,03934821 0,14474799 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,03934821 0,14445965 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,03934821 0,14417245 ! astrocyte differentiation GO:0048708 5 5 0,000 0,03934821 0,1438864 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,03934821 0,14360147 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,03934821 0,14331767 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,03934821 0,143035 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,03934821 0,14275343 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,03934821 0,14247297 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,03934821 0,14219361 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,03934821 0,14191535 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,03934821 0,14163817 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,03934821 0,14136207 ! muscle cell migration GO:0014812 5 5 0,000 0,03934821 0,14108705 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,03934821 0,14081309 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,03934821 0,1405402 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,03934821 0,14026836 ! response to ATP GO:0033198 5 5 0,000 0,03934821 0,13999757 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,03934821 0,13972783 ! regulation of appetite GO:0032098 5 5 0,000 0,03934821 0,13945912 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,03934821 0,13919145 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,03934821 0,1389248 ! regulation of phospholipase A2 activity GO:0032429 5 5 0,000 0,03934821 0,13865916 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,03934821 0,13839455 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,03934821 0,13813094 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03934821 0,13786833 ! receptor clustering GO:0043113 5 5 0,000 0,03934821 0,13760672 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,03934821 0,1373461 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,03934821 0,13708647 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,03934821 0,13682782 ! retinol metabolic process GO:0042572 5 5 0,000 0,03934821 0,13657014 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,03934821 0,13631343 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,03934821 0,13605768 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,03934821 0,13580289 ! parturition GO:0007567 5 5 0,000 0,03934821 0,13554905 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03934821 0,13529616 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,03934821 0,13504421 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,03934821 0,1347932 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,03934821 0,13454312 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,03934821 0,13429397 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,03934821 0,13404574 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,03934821 0,13379842 ! oligodendrocyte development GO:0014003 5 5 0,000 0,03934821 0,13355201 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,03934821 0,13330651 ! activated T cell proliferation GO:0050798 5 5 0,000 0,03934821 0,13306191 ! interaction with symbiont GO:0051702 5 5 0,000 0,03934821 0,13281821 ! cellular extravasation GO:0045123 5 5 0,000 0,03934821 0,1325754 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,03934821 0,13233347 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,03934821 0,13209243 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,03934821 0,13185226 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,03934821 0,13161296 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,03934821 0,13137453 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,03934821 0,13113697 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,03934821 0,13090026 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,03934821 0,1306644 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,03934821 0,13042939 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,03934821 0,13019523 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,03934821 0,12996191 ! neuron recognition GO:0008038 5 5 0,000 0,03934821 0,12972942 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,03934821 0,12949776 ! decidualization GO:0046697 5 5 0,000 0,03934821 0,12926692 ! hair follicle maturation GO:0048820 5 5 0,000 0,03934821 0,12903691 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,03934821 0,12880771 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,03934821 0,12857933 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,03934821 0,12835176 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,03934821 0,12812499 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,03934821 0,12789902 ! postreplication repair GO:0006301 5 5 0,000 0,03934821 0,12767384 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,03934821 0,12744946 GO:0021517|ventral spinal cord development, ! DNA methylation GO:0006306 5 5 0,000 0,03934821 0,12722587 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03934821 0,12700305 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,03934821 0,12678102 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,03934821 0,12655976 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,03934821 0,12633927 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,03934821 0,12611955 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,03934821 0,1259006 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,03934821 0,1256824 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,03934821 0,12546495 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,03934821 0,12524826 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,03934821 0,12503232 ! sterol catabolic process GO:0016127 5 5 0,000 0,03934821 0,12481711 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,03934821 0,12460265 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,03934821 0,12438892 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,03934821 0,12417593 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,03934821 0,12396366 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,03934821 0,12375212 ! zymogen activation GO:0031638 5 5 0,000 0,03934821 0,1235413 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,03934821 0,1233312 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,03934821 0,12312181 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,03934821 0,12291312 ! nucleosome positioning GO:0016584 5 5 0,000 0,03934821 0,12270515 ! regulation of isotype switching GO:0045191 5 5 0,000 0,03934821 0,12249788 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,03934821 0,1222913 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,03934821 0,12208543 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,03934821 0,12188024 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,03934821 0,12167574 ! NADPH regeneration GO:0006740 5 5 0,000 0,03934821 0,12147193 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,03934821 0,1212688 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,03934821 0,12106635 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,03934821 0,12086457 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,03934821 0,12066347 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,03934821 0,12046303 ! sarcomere organization GO:0045214 5 5 0,000 0,03934821 0,12026326 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,03934821 0,12006414 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,03934821 0,11986569 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,03934821 0,11966789 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,03934821 0,11947075 GO:0045622|regulation of T-helper cell differentiation, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,03934821 0,11927425 ! male genitalia development GO:0030539 5 5 0,000 0,03934821 0,1190784 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,03934821 0,11888319 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,03934821 0,11868861 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,03934821 0,11849468 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,03934821 0,11830138 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,03934821 0,1181087 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,03934821 0,11791666 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,03934821 0,11772523 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,03934821 0,11753443 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,03934821 0,11734424 ! ATP catabolic process GO:0006200 5 5 0,000 0,03934821 0,11715467 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03934821 0,11696571 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,03934821 0,11677736 ! blastocyst formation GO:0001825 5 5 0,000 0,03934821 0,11658962 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,03934821 0,11640248 ! embryonic gut development GO:0048566 5 5 0,000 0,03934821 0,11621593 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,03934821 0,11602999 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,03934821 0,11584464 ! activation of innate immune response GO:0002218 5 5 0,000 0,03934821 0,11565988 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,03934821 0,11547571 ! catecholamine transport GO:0051937 5 5 0,000 0,03934821 0,11529212 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,03934821 0,11510912 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,03934821 0,11492669 ! muscle adaptation GO:0043500 5 5 0,000 0,03934821 0,11474485 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,03934821 0,11456358 ! embryonic heart tube development GO:0035050 5 5 0,000 0,03934821 0,11438288 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,03934821 0,11420275 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,03934821 0,11402318 ! defense response to fungus GO:0050832 5 5 0,000 0,03934821 0,11384418 ! lysogeny GO:0030069 5 5 0,000 0,03934821 0,11366574 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,03934821 0,11348786 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,03934821 0,11331054 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,03934821 0,11313376 ! establishment of cell polarity GO:0030010 5 5 0,000 0,03934821 0,11295754 ! mitochondrion localization GO:0051646 5 5 0,000 0,03934821 0,11278187 ! nucleus localization GO:0051647 5 5 0,000 0,03934821 0,11260674 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,03934821 0,11243216 ! vasculature development GO:0001944 97 96 2,000 0,04099621 0,11695977 ! cell cycle checkpoint GO:0000075 42 41 1,000 0,04218261 0,12015851 ! regulation of caspase activity GO:0043281 41 41 1,000 0,04218261 0,11997308 ! posttranscriptional regulation of gene expression GO:0010608 98 98 2,000 0,04316058 0,12256541 ! regulation of system process GO:0044057 98 98 2,000 0,04316058 0,12237685 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,04406914 0,12476101 ! development of primary sexual characteristics GO:0045137 42 42 1,000 0,04406914 0,12456966 ! response to protein stimulus GO:0051789 42 42 1,000 0,04406914 0,1243789 ! one-carbon metabolic process GO:0006730 42 42 1,000 0,04406914 0,12418871 ! ectoderm development GO:0007398 99 99 2,000 0,04426405 0,12454754 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 2,000 0,04538162 0,12749746 ! hemopoiesis GO:0030097 104 100 2,000 0,04538162 0,1273034 ! homeostasis of number of cells GO:0048872 44 43 1,000 0,04598669 0,12880467 ! axon extension GO:0048675 7 6 0,000 0,04703342 0,13153656 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,04703342 0,13133726 ! tRNA modification GO:0006400 6 6 0,000 0,04703342 0,13113857 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,04703342 0,13094047 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,04703342 0,13074298 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,04703342 0,13054607 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,04703342 0,13034976 ! regulation of S phase GO:0033261 6 6 0,000 0,04703342 0,13015404 ! myotube differentiation GO:0014902 6 6 0,000 0,04703342 0,12995891 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,04703342 0,12976436 ! bone remodeling GO:0046849 6 6 0,000 0,04703342 0,12957039 ! N-glycan processing GO:0006491 6 6 0,000 0,04703342 0,129377 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,04703342 0,12918419 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,04703342 0,12899195 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,04703342 0,12880029 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,04703342 0,12860919 ! RNA methylation GO:0001510 6 6 0,000 0,04703342 0,12841866 ! cartilage condensation GO:0001502 7 6 0,000 0,04703342 0,12822869 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,04703342 0,12803928 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,04703342 0,12785043 GO:0050927|positive regulation of positive chemotaxis, ! artery development GO:0060840 6 6 0,000 0,04703342 0,12766214 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,04703342 0,1274744 ! bile acid metabolic process GO:0008206 6 6 0,000 0,04703342 0,12728721 ! androgen metabolic process GO:0008209 6 6 0,000 0,04703342 0,12710058 ! estrogen metabolic process GO:0008210 6 6 0,000 0,04703342 0,12691449 ! limbic system development GO:0021761 7 6 0,000 0,04703342 0,12672894 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,04703342 0,12654393 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,04703342 0,12635947 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,04703342 0,12617554 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,04703342 0,12599214 ! pathogenesis GO:0009405 6 6 0,000 0,04703342 0,12580928 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,04703342 0,12562695 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,04703342 0,12544514 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,04703342 0,12526386 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,04703342 0,12508311 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,04703342 0,12490287 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,04703342 0,12472316 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,04703342 0,12454396 ! arginine metabolic process GO:0006525 6 6 0,000 0,04703342 0,12436527 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,04703342 0,1241871 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,04703342 0,12400943 ! glutamate catabolic process GO:0006538 7 6 0,000 0,04703342 0,12383228 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,04703342 0,12365563 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,04703342 0,12347948 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,04703342 0,12330383 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,04703342 0,12312868 ! V(D)J recombination GO:0033151 6 6 0,000 0,04703342 0,12295403 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,04703342 0,12277988 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 0,04703342 0,12260621 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,04703342 0,12243304 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,04703342 0,12226036 ! regulation of heart rate GO:0002027 6 6 0,000 0,04703342 0,12208816 ! lipid digestion GO:0044241 6 6 0,000 0,04703342 0,12191645 ! asymmetric protein localization GO:0008105 6 6 0,000 0,04703342 0,12174522 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,04703342 0,12157446 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,04703342 0,12140419 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,04703342 0,1212344 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,04703342 0,12106507 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,04703342 0,12089622 ! ruffle organization GO:0031529 6 6 0,000 0,04703342 0,12072785 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,04703342 0,12055994 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,04703342 0,12039249 ! neutral amino acid transport GO:0015804 6 6 0,000 0,04703342 0,12022551 ! L-amino acid transport GO:0015807 6 6 0,000 0,04703342 0,12005899 ! bone mineralization GO:0030282 6 6 0,000 0,04703342 0,11989294 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,04703342 0,11972734 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,04703342 0,1195622 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,04703342 0,11939751 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,04703342 0,11923328 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,04703342 0,1190695 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,04703342 0,11890616 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,04703342 0,11874328 ! regulation of organ growth GO:0046620 6 6 0,000 0,04703342 0,11858084 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,04703342 0,11841884 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,04703342 0,11825729 ! response to dsRNA GO:0043331 6 6 0,000 0,04703342 0,11809618 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,04703342 0,1179355 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,04703342 0,11777526 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 0,04703342 0,11761546 ! genitalia development GO:0048806 6 6 0,000 0,04703342 0,11745609 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,04703342 0,11729715 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,04703342 0,11713864 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 0,04703342 0,11698056 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,04703342 0,1168229 ! multicellular organismal aging GO:0010259 6 6 0,000 0,04703342 0,11666567 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,04703342 0,11650886 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,04703342 0,11635247 ! erythrocyte development GO:0048821 6 6 0,000 0,04703342 0,11619651 ! renal water homeostasis GO:0003091 6 6 0,000 0,04703342 0,11604095 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,04703342 0,11588582 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,04703342 0,1157311 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,04703342 0,11557679 ! ribosome assembly GO:0042255 6 6 0,000 0,04703342 0,11542289 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,04703342 0,11526941 ! diencephalon development GO:0021536 6 6 0,000 0,04703342 0,11511633 ! fucose catabolic process GO:0019317 6 6 0,000 0,04703342 0,11496365 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,04703342 0,11481138 GO:0006809|nitric oxide biosynthetic process, ! regulation of lipid transport GO:0032368 6 6 0,000 0,04703342 0,11465951 ! regulation of cell division GO:0051302 6 6 0,000 0,04703342 0,11450805 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,04703342 0,11435698 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,04703342 0,11420632 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,04703342 0,11405604 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,04703342 0,11390617 ! neuroblast proliferation GO:0007405 6 6 0,000 0,04703342 0,11375668 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,04703342 0,11360759 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,04703342 0,11345889 ! regulation of glucose transport GO:0010827 6 6 0,000 0,04703342 0,11331058 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,04703342 0,11316265 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,04703342 0,11301512 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,04703342 0,11286796 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,04703342 0,11272119 ! lymph node development GO:0048535 6 6 0,000 0,04703342 0,1125748 ! organic cation transport GO:0015695 6 6 0,000 0,04703342 0,11242879 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,04703342 0,11228315 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,04703342 0,1121379 ! sperm-egg recognition GO:0035036 7 6 0,000 0,04703342 0,11199301 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,04703342 0,11184851 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,04703342 0,11170437 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,04703342 0,11156061 ! alditol metabolic process GO:0019400 6 6 0,000 0,04703342 0,11141722 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,04703342 0,11127419 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,04703342 0,11113153 ! maternal placenta development GO:0001893 6 6 0,000 0,04703342 0,11098924 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,04703342 0,11084731 ! localization within membrane GO:0051668 6 6 0,000 0,04703342 0,11070574 ! protein import into nucleus GO:0006606 44 44 1,000 0,04793469 0,1126832 ! humoral immune response GO:0006959 44 44 1,000 0,04793469 0,11253965 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,04991253 0,11703409 ! nuclear import GO:0051170 45 45 1,000 0,04991253 0,11688538 ! Wnt receptor signaling pathway GO:0016055 46 45 1,000 0,04991253 0,11673705 ! protein processing GO:0016485 45 45 1,000 0,04991253 0,11658909 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,05191964 0,12112391 ! amine transport GO:0015837 47 47 1,000 0,05395544 0,12571412 ! rhythmic process GO:0048511 47 47 1,000 0,05395544 0,12555539 ! respiratory burst GO:0045730 7 7 0,000 0,05465826 0,12703049 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,05465826 0,1268705 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,05465826 0,12671091 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,05465826 0,12655173 ! regulation of chemokine production GO:0032642 7 7 0,000 0,05465826 0,12639294 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,05465826 0,12623456 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,05465826 0,12607657 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,05465826 0,12591897 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,05465826 0,12576177 GO:0043241|protein complex disassembly, ! gene silencing by RNA GO:0031047 7 7 0,000 0,05465826 0,12560496 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,05465826 0,12544854 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,05465826 0,12529251 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,05465826 0,12513687 ! axis specification GO:0009798 7 7 0,000 0,05465826 0,12498161 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,05465826 0,12482674 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,05465826 0,12467225 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,05465826 0,12451814 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,05465826 0,12436442 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,05465826 0,12421107 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,05465826 0,1240581 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,05465826 0,12390551 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,05465826 0,12375329 ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,05465826 0,12360144 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,05465826 0,12344997 ! protein targeting to ER GO:0045047 8 7 0,000 0,05465826 0,12329887 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,05465826 0,12314814 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,05465826 0,12299777 ! endoderm development GO:0007492 7 7 0,000 0,05465826 0,12284778 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,05465826 0,12269814 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,05465826 0,12254888 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,05465826 0,12239997 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,05465826 0,12225143 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 0,05465826 0,12210324 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,05465826 0,12195542 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,05465826 0,12180795 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,05465826 0,12166084 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,05465826 0,12151409 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,05465826 0,12136768 ! UV protection GO:0009650 7 7 0,000 0,05465826 0,12122163 ! DNA integration GO:0015074 7 7 0,000 0,05465826 0,12107593 ! myofibril assembly GO:0030239 7 7 0,000 0,05465826 0,12093058 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,05465826 0,12078558 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,05465826 0,12064093 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,05465826 0,12049662 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,05465826 0,12035266 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,05465826 0,12020904 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,05465826 0,12006576 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,05465826 0,11992283 GO:0019827|stem cell maintenance, ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,05465826 0,11978023 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,05465826 0,11963798 ! eating behavior GO:0042755 7 7 0,000 0,05465826 0,11949606 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,05465826 0,11935447 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,05465826 0,11921323 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,05465826 0,11907231 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,05465826 0,11893173 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,05465826 0,11879148 ! cranial nerve development GO:0021545 7 7 0,000 0,05465826 0,11865156 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,05465826 0,11851197 ! induction of an organ GO:0001759 7 7 0,000 0,05465826 0,11837271 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,05465826 0,11823378 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,05465826 0,11809517 ! autonomic nervous system development GO:0048483 7 7 0,000 0,05465826 0,11795688 ! intracellular lipid transport GO:0032365 7 7 0,000 0,05465826 0,11781892 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,05465826 0,11768128 ! platelet activation GO:0030168 8 7 0,000 0,05465826 0,11754396 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,05465826 0,11740697 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,05465826 0,11727029 ! natural killer cell activation GO:0030101 7 7 0,000 0,05465826 0,11713393 ! NADP metabolic process GO:0006739 7 7 0,000 0,05465826 0,11699788 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,05465826 0,11686215 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,05465826 0,11672674 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,05465826 0,11659164 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,05465826 0,11645685 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,05465826 0,11632237 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,05465826 0,11618821 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,05465826 0,11605435 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,05465826 0,1159208 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,05465826 0,11578756 ! cell-cell recognition GO:0009988 8 7 0,000 0,05465826 0,11565462 ! hormone catabolic process GO:0042447 7 7 0,000 0,05465826 0,11552199 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,05465826 0,11538966 ! oxygen transport GO:0015671 7 7 0,000 0,05465826 0,11525764 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,05465826 0,11512592 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,05465826 0,11499449 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,05465826 0,11486337 ! regulation of axon extension GO:0030516 7 7 0,000 0,05465826 0,11473255 ! cell killing GO:0001906 7 7 0,000 0,05465826 0,11460202 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,05465826 0,11447179 ! adult feeding behavior GO:0008343 7 7 0,000 0,05465826 0,11434186 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,05465826 0,11421222 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,05465826 0,11408287 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,05465826 0,11395382 ! negative regulation of T cell activation GO:0050868 7 7 0,000 0,05465826 0,11382506 ! response to cold GO:0009409 7 7 0,000 0,05465826 0,11369659 ! calcium ion transport GO:0006816 48 48 1,000 0,05601936 0,11639648 ! protein localization in nucleus GO:0034504 48 48 1,000 0,05601936 0,1162654 ! divalent metal ion transport GO:0070838 49 49 1,000 0,05811084 0,1204705 ! skeletal muscle tissue development GO:0007519 50 49 1,000 0,05811084 0,12033514 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 1,000 0,05811084 0,12020009 ! regulation of defense response GO:0031347 50 50 1,000 0,06022933 0,12444244 ! negative regulation of transport GO:0051051 51 50 1,000 0,06022933 0,12430308 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,06022933 0,12416404 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,0622232 0,12813112 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,0622232 0,12798812 ! positive regulation of translation GO:0045727 8 8 0,000 0,0622232 0,12784543 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,0622232 0,12770306 ! superoxide anion generation GO:0042554 8 8 0,000 0,0622232 0,12756101 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,0622232 0,12741928 ! cGMP metabolic process GO:0046068 8 8 0,000 0,0622232 0,12727786 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,0622232 0,12713675 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,0622232 0,12699596 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,0622232 0,12685548 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,0622232 0,12671531 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,0622232 0,12657544 ! zinc ion transport GO:0006829 8 8 0,000 0,0622232 0,12643589 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,0622232 0,12629664 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,0622232 0,1261577 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,0622232 0,12601907 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,0622232 0,12588074 ! lipid localization GO:0010876 8 8 0,000 0,0622232 0,12574271 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,0622232 0,12560498 ! response to cAMP GO:0051591 8 8 0,000 0,0622232 0,12546756 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,0622232 0,12533044 GO:0048200|Golgi transport vesicle coating, ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,0622232 0,12519361 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,0622232 0,12505709 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,0622232 0,12492086 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,0622232 0,12478493 ! sensory perception of taste GO:0050909 8 8 0,000 0,0622232 0,12464929 ! organelle fusion GO:0048284 8 8 0,000 0,0622232 0,12451395 ! pancreas development GO:0031016 8 8 0,000 0,0622232 0,12437891 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,0622232 0,12424415 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,0622232 0,12410969 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,0622232 0,12397551 ! sperm motility GO:0030317 8 8 0,000 0,0622232 0,12384163 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,0622232 0,12370804 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,0622232 0,12357473 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,0622232 0,12344171 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,0622232 0,12330898 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,0622232 0,12317653 GO:0031114|regulation of microtubule depolymerization, ! polyamine metabolic process GO:0006595 8 8 0,000 0,0622232 0,12304437 ! Golgi organization GO:0007030 8 8 0,000 0,0622232 0,12291249 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,0622232 0,12278089 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,0622232 0,12264957 ! mannose metabolic process GO:0006013 9 8 0,000 0,0622232 0,12251854 ! NAD metabolic process GO:0019674 8 8 0,000 0,0622232 0,12238778 ! plasma membrane fusion GO:0045026 8 8 0,000 0,0622232 0,1222573 ! response to fungus GO:0009620 8 8 0,000 0,0622232 0,1221271 ! stem cell differentiation GO:0048863 8 8 0,000 0,0622232 0,12199718 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,0622232 0,12186754 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,0622232 0,12173816 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,0622232 0,12160907 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,0622232 0,12148024 ! regulation of vasodilation GO:0042312 8 8 0,000 0,0622232 0,12135169 ! vasoconstriction GO:0042310 8 8 0,000 0,0622232 0,12122342 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,0622232 0,12109541 ! muscle cell development GO:0055001 8 8 0,000 0,0622232 0,12096767 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,0622232 0,1208402 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,0622232 0,120713 ! sensory perception of pain GO:0019233 8 8 0,000 0,0622232 0,12058607 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,0622232 0,1204594 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,0622232 0,120333 ! chromatin silencing GO:0006342 8 8 0,000 0,0622232 0,12020687 ! tissue regeneration GO:0042246 8 8 0,000 0,0622232 0,120081 ! salivary gland development GO:0007431 8 8 0,000 0,0622232 0,11995539 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,0622232 0,11983004 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,0622232 0,11970496 ! water homeostasis GO:0030104 8 8 0,000 0,0622232 0,11958014 ! cofactor transport GO:0051181 8 8 0,000 0,0622232 0,11945557 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,0622232 0,11933127 ! acid secretion GO:0046717 8 8 0,000 0,0622232 0,11920723 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,0622232 0,11908344 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,0622232 0,11895991 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,0622232 0,11883663 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,0622232 0,11871361 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,0622232 0,11859085 ! regulation of RNA stability GO:0043487 8 8 0,000 0,0622232 0,11846834 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,0622232 0,11834608 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,0622232 0,11822407 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,0622232 0,11810232 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,0622232 0,11798081 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,0622232 0,11785956 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,0622232 0,11773855 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,0622232 0,1176178 ! developmental induction GO:0031128 8 8 0,000 0,0622232 0,11749729 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,0622232 0,11737702 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,0622232 0,11725701 ! actin filament polymerization GO:0030041 9 8 0,000 0,0622232 0,11713723 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,0622232 0,11701771 ! peptide hormone processing GO:0016486 8 8 0,000 0,0622232 0,11689842 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,0622232 0,11677938 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,0622232 0,11666058 ! biogenic amine metabolic process GO:0006576 52 51 1,000 0,06237428 0,11682499 ! rRNA metabolic process GO:0016072 51 51 1,000 0,06237428 0,11670639 GO:0006364|rRNA processing, ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 0,06237428 0,11658803 GO:0051325|interphase, ! protein maturation GO:0051604 51 51 1,000 0,06237428 0,1164699 ! regulation of protein transport GO:0051223 53 53 1,000 0,0667414 0,12449838 GO:0070201|regulation of establishment of protein localization, ! response to virus GO:0009615 54 54 1,000 0,06896251 0,12851154 ! sulfur metabolic process GO:0006790 55 54 1,000 0,06896251 0,12838173 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,06896251 0,12825218 ! lactation GO:0007595 10 9 0,000 0,06972869 0,12954634 ! embryonic pattern specification GO:0009880 10 9 0,000 0,06972869 0,12941588 ! positive regulation of cell size GO:0045793 9 9 0,000 0,06972869 0,12928568 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,06972869 0,12915575 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,06972869 0,12902607 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,06972869 0,12889666 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,06972869 0,1287675 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 0,000 0,06972869 0,12863861 ! viral genome replication GO:0019079 9 9 0,000 0,06972869 0,12850997 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,06972869 0,12838159 ! copper ion transport GO:0006825 9 9 0,000 0,06972869 0,12825346 ! lipid phosphorylation GO:0046834 9 9 0,000 0,06972869 0,12812559 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,06972869 0,12799798 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,06972869 0,12787062 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,06972869 0,12774351 ! RNA polyadenylation GO:0043631 9 9 0,000 0,06972869 0,12761665 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,06972869 0,12749005 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,06972869 0,1273637 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,06972869 0,12723759 ! phospholipid efflux GO:0033700 9 9 0,000 0,06972869 0,12711174 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,06972869 0,12698613 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,06972869 0,12686078 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,06972869 0,12673567 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,06972869 0,12661081 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,06972869 0,12648619 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,06972869 0,12636182 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,06972869 0,12623769 ! methionine metabolic process GO:0006555 9 9 0,000 0,06972869 0,12611381 ! glutamine metabolic process GO:0006541 9 9 0,000 0,06972869 0,12599017 ! cerebral cortex development GO:0021987 9 9 0,000 0,06972869 0,12586677 ! pigmentation during development GO:0048066 9 9 0,000 0,06972869 0,12574361 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,06972869 0,12562069 ! central nervous system neuron development GO:0021954 10 9 0,000 0,06972869 0,12549802 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,06972869 0,12537558 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,06972869 0,12525338 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,06972869 0,12513142 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,06972869 0,1250097 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,06972869 0,12488821 ! L-glutamate transport GO:0015813 9 9 0,000 0,06972869 0,12476696 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,06972869 0,12464594 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,06972869 0,12452516 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,06972869 0,12440462 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,06972869 0,1242843 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,06972869 0,12416422 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,06972869 0,12404437 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,06972869 0,12392475 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,06972869 0,12380536 ! DNA replication initiation GO:0006270 9 9 0,000 0,06972869 0,12368621 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,06972869 0,12356728 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,06972869 0,12344858 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,06972869 0,1233301 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,06972869 0,12321186 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,06972869 0,12309384 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,06972869 0,12297605 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,06972869 0,12285848 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,06972869 0,12274113 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,06972869 0,12262402 ! collagen catabolic process GO:0030574 9 9 0,000 0,06972869 0,12250712 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,06972869 0,12239045 ! purine base metabolic process GO:0006144 9 9 0,000 0,06972869 0,12227399 ! gas transport GO:0015669 9 9 0,000 0,06972869 0,12215776 ! cholesterol efflux GO:0033344 9 9 0,000 0,06972869 0,12204176 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,06972869 0,12192597 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,06972869 0,1218104 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,06972869 0,12169505 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,06972869 0,12157991 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,06972869 0,121465 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,06972869 0,1213503 ! actin filament-based movement GO:0030048 9 9 0,000 0,06972869 0,12123582 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,06972869 0,12112155 ! in utero embryonic development GO:0001701 55 55 1,000 0,07120796 0,12357464 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,07717519 0,13380421 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,07717519 0,13367845 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,07717519 0,13355293 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,07717519 0,13342765 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,07717519 0,1333026 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,07717519 0,13317778 ! neuron maturation GO:0042551 10 10 0,000 0,07717519 0,1330532 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,07717519 0,13292885 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,07717519 0,13280474 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,07717519 0,13268085 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,07717519 0,1325572 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,07717519 0,13243377 ! hormone secretion GO:0046879 10 10 0,000 0,07717519 0,13231058 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,07717519 0,13218761 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,07717519 0,13206488 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,07717519 0,13194237 ! cAMP metabolic process GO:0046058 10 10 0,000 0,07717519 0,13182009 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,07717519 0,13169803 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,07717519 0,1315762 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,07717519 0,1314546 ! glial cell development GO:0021782 10 10 0,000 0,07717519 0,13133322 ! phototransduction GO:0007602 11 10 0,000 0,07717519 0,13121206 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,07717519 0,13109113 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,07717519 0,13097042 ! fat cell differentiation GO:0045444 10 10 0,000 0,07717519 0,13084993 ! myoblast differentiation GO:0045445 10 10 0,000 0,07717519 0,13072966 ! centrosome cycle GO:0007098 10 10 0,000 0,07717519 0,13060962 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,07717519 0,13048979 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,07717519 0,13037019 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,07717519 0,1302508 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,07717519 0,13013163 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,07717519 0,13001268 ! protein polyubiquitination GO:0000209 10 10 0,000 0,07717519 0,12989395 ! glutamate metabolic process GO:0006536 11 10 0,000 0,07717519 0,12977543 ! plasma membrane organization GO:0007009 10 10 0,000 0,07717519 0,12965713 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,07717519 0,12953905 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,07717519 0,12942118 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,07717519 0,12930352 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,07717519 0,12918608 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,07717519 0,12906885 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,07717519 0,12895183 ! exocrine system development GO:0035272 10 10 0,000 0,07717519 0,12883503 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,07717519 0,12871844 ! neuromuscular junction development GO:0007528 10 10 0,000 0,07717519 0,12860206 ! embryo implantation GO:0007566 11 10 0,000 0,07717519 0,12848588 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,07717519 0,12836992 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,07717519 0,12825417 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,07717519 0,12813862 ! protein export from nucleus GO:0006611 10 10 0,000 0,07717519 0,12802329 ! negative regulation of immune response GO:0050777 10 10 0,000 0,07717519 0,12790816 ! cytolysis GO:0019835 10 10 0,000 0,07717519 0,12779324 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,07717519 0,12767852 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,07717519 0,12756401 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,07717519 0,12744971 ! histone deacetylation GO:0016575 10 10 0,000 0,07717519 0,12733561 ! mRNA splice site selection GO:0006376 11 10 0,000 0,07717519 0,12722171 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,07717519 0,12710802 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,07717519 0,12699453 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,07717519 0,12688124 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,07717519 0,12676816 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,07717519 0,12665527 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,07717519 0,12654259 ! regulation of epidermis development GO:0045682 10 10 0,000 0,07717519 0,12643011 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,07717519 0,12631783 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,07717519 0,12620574 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,07717519 0,12609386 ! nerve development GO:0021675 10 10 0,000 0,07717519 0,12598217 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,07717519 0,12587068 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,07717519 0,12575939 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,07717519 0,1256483 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,07717519 0,1255374 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,07717519 0,1254267 ! protein stabilization GO:0050821 10 10 0,000 0,07717519 0,12531619 ! carboxylic acid transport GO:0046942 59 59 1,000 0,08042292 0,13047487 GO:0015849|organic acid transport, ! cellular aromatic compound metabolic process GO:0006725 60 59 1,000 0,08042292 0,13036011 ! protein localization in organelle GO:0033365 59 59 1,000 0,08042292 0,13024556 ! immune effector process GO:0002252 59 59 1,000 0,08042292 0,13013121 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,08278247 0,13383165 ! protein polymerization GO:0051258 65 60 1,000 0,08278247 0,13371436 ! protein secretion GO:0009306 11 11 0,000 0,08456316 0,13647102 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,08456316 0,13635162 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,08456316 0,13623243 ! negative regulation of defense response GO:0031348 11 11 0,000 0,08456316 0,13611345 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,08456316 0,13599468 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,08456316 0,13587612 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,08456316 0,13575776 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,08456316 0,1356396 ! skin development GO:0043588 11 11 0,000 0,08456316 0,13552166 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,08456316 0,13540391 ! signal complex assembly GO:0007172 11 11 0,000 0,08456316 0,13528638 ! endothelial cell migration GO:0043542 11 11 0,000 0,08456316 0,13516904 ! peroxisomal transport GO:0043574 11 11 0,000 0,08456316 0,13505191 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,08456316 0,13493498 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,08456316 0,13481826 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,08456316 0,13470173 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,08456316 0,13458541 ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,08456316 0,13446929 ! spinal cord development GO:0021510 11 11 0,000 0,08456316 0,13435337 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,08456316 0,13423764 ! smooth muscle contraction GO:0006939 11 11 0,000 0,08456316 0,13412212 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,08456316 0,1340068 ! digestive system process GO:0022600 11 11 0,000 0,08456316 0,13389167 ! mitotic spindle organization GO:0007052 11 11 0,000 0,08456316 0,13377674 ! fucose metabolic process GO:0006004 11 11 0,000 0,08456316 0,13366201 ! membrane budding GO:0006900 11 11 0,000 0,08456316 0,13354748 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,08456316 0,13343314 ! monoamine transport GO:0015844 11 11 0,000 0,08456316 0,13331899 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,08456316 0,13320505 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,08456316 0,13309129 ! body fluid secretion GO:0007589 11 11 0,000 0,08456316 0,13297773 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,08456316 0,13286437 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,08456316 0,1327512 GO:0060415|muscle tissue morphogenesis, ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,08456316 0,13263822 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,08456316 0,13252543 ! regulation of monooxygenase activity GO:0032768 11 11 0,000 0,08456316 0,13241283 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,08456316 0,13230043 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,08456316 0,13218821 ! vitamin transport GO:0051180 11 11 0,000 0,08456316 0,13207619 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,08456316 0,13196436 ! steroid catabolic process GO:0006706 11 11 0,000 0,08456316 0,13185271 ! endocrine process GO:0050886 11 11 0,000 0,08456316 0,13174126 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,08456316 0,13162999 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,08456316 0,13151891 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,08456316 0,13140801 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,08456316 0,13129731 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,08456316 0,13118679 ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 0,08516335 0,13200678 ! axonogenesis GO:0007409 66 62 1,000 0,08756511 0,13561554 ! protein import GO:0017038 62 62 1,000 0,08756511 0,13550167 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 1,000 0,08756511 0,135388 ! translational initiation GO:0006413 12 12 0,000 0,09189305 0,14196052 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,09189305 0,14184162 ! initiation of viral infection GO:0019059 12 12 0,000 0,09189305 0,14172293 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,09189305 0,14160443 ! iron ion transport GO:0006826 13 12 0,000 0,09189305 0,14148613 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,09189305 0,14136803 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,09189305 0,14125012 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,09189305 0,14113241 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,09189305 0,1410149 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,09189305 0,14089758 ! collagen metabolic process GO:0032963 12 12 0,000 0,09189305 0,14078046 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,09189305 0,14066353 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,09189305 0,1405468 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,09189305 0,14043026 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,09189305 0,14031391 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,09189305 0,14019776 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,09189305 0,1400818 ! actomyosin structure organization GO:0031032 12 12 0,000 0,09189305 0,13996603 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,09189305 0,13985045 GO:0051297|centrosome organization, ! retinoid metabolic process GO:0001523 12 12 0,000 0,09189305 0,13973506 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,09189305 0,13961986 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,09189305 0,13950486 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,09189305 0,13939004 GO:0006505|GPI anchor metabolic process, ! acute-phase response GO:0006953 12 12 0,000 0,09189305 0,13927541 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,09189305 0,13916097 ! vacuolar transport GO:0007034 12 12 0,000 0,09189305 0,13904671 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,09189305 0,13893265 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,09189305 0,13881877 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,09189305 0,13870507 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,09189305 0,13859157 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,09189305 0,13847825 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,09189305 0,13836511 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,09189305 0,13825216 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,09189305 0,13813939 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,09189305 0,13802681 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,09189305 0,13791441 ! pallium development GO:0021543 13 12 0,000 0,09189305 0,13780219 ! cell fate determination GO:0001709 12 12 0,000 0,09189305 0,13769016 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,09189305 0,13757831 ! G1 phase GO:0051318 13 12 0,000 0,09189305 0,13746664 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,09189305 0,13735515 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,09189305 0,13724384 ! detection of light stimulus GO:0009583 13 12 0,000 0,09189305 0,13713271 ! synaptogenesis GO:0007416 12 12 0,000 0,09189305 0,13702176 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,09189305 0,13691099 ! hormone transport GO:0009914 12 12 0,000 0,09189305 0,1368004 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,09189305 0,13668999 ! heme biosynthetic process GO:0006783 12 12 0,000 0,09189305 0,13657975 ! spermatid differentiation GO:0048515 13 12 0,000 0,09189305 0,1364697 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,09189305 0,13635982 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,09189305 0,13625012 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,09189305 0,13614059 ! negative regulation of translation GO:0017148 12 12 0,000 0,09189305 0,13603124 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,09242934 0,13671531 ! angiogenesis GO:0001525 65 64 1,000 0,09242934 0,13660568 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 0,09242934 0,13649622 ! anion transport GO:0006820 65 65 1,000 0,0948909 0,14001916 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,0948909 0,13990714 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,09916531 0,14609246 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,09916531 0,14597578 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,09916531 0,14585927 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,09916531 0,14574296 ! gluconeogenesis GO:0006094 13 13 0,000 0,09916531 0,14562683 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,09916531 0,14551088 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,09916531 0,14539512 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,09916531 0,14527955 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,09916531 0,14516415 ! keratinization GO:0031424 13 13 0,000 0,09916531 0,14504894 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,09916531 0,14493392 ! patterning of blood vessels GO:0001569 13 13 0,000 0,09916531 0,14481907 ! vasculogenesis GO:0001570 13 13 0,000 0,09916531 0,14470441 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,09916531 0,14458993 ! regulation of innate immune response GO:0045088 13 13 0,000 0,09916531 0,14447563 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,09916531 0,14436151 ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,09916531 0,14424757 ! autophagy GO:0006914 13 13 0,000 0,09916531 0,14413381 ! receptor metabolic process GO:0043112 14 13 0,000 0,09916531 0,14402023 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,09916531 0,14390683 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,09916531 0,1437936 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,09916531 0,14368056 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,09916531 0,14356769 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,09916531 0,143455 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,09916531 0,14334249 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,09916531 0,14323015 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,09916531 0,14311799 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,09916531 0,143006 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,09916531 0,14289419 ! vasodilation GO:0042311 14 13 0,000 0,09916531 0,14278256 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,09916531 0,14267109 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,09916531 0,14255981 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,09916531 0,14244869 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,09916531 0,14233775 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,09916531 0,14222698 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,09916531 0,14211638 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,09916531 0,14200596 ! immunoglobulin production GO:0002377 13 13 0,000 0,09916531 0,14189571 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,09916531 0,14178563 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,09916531 0,14167571 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,09916531 0,14156597 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,09916531 0,1414564 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,09916531 0,141347 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,09916531 0,14123777 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,09916531 0,1411287 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,09916531 0,14101981 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,09916531 0,14091108 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,09916531 0,14080252 ! blastocyst development GO:0001824 13 13 0,000 0,09916531 0,14069413 ! telomere organization GO:0032200 13 13 0,000 0,09916531 0,1405859 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,09916531 0,14047784 ! regulation of amine transport GO:0051952 13 13 0,000 0,09916531 0,14036995 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,09916531 0,14026222 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,09987062 0,1411515 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! striated muscle tissue development GO:0014706 69 67 1,000 0,09987062 0,14104334 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,09987062 0,14093534 ! Ras protein signal transduction GO:0007265 69 67 1,000 0,09987062 0,14082751 ! regulation of translation GO:0006417 69 69 1,000 0,10492287 0,14783857 ! regionalization GO:0003002 70 69 1,000 0,10492287 0,14772563 ! neuron fate commitment GO:0048663 14 14 0,000 0,10638039 0,1496634 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,10638039 0,14954924 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,10638039 0,14943525 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,10638039 0,14932144 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,10638039 0,1492078 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,10638039 0,14909434 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,10638039 0,14898104 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,10638039 0,14886792 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,10638039 0,14875497 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,10638039 0,14864219 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,10638039 0,14852958 ! superoxide metabolic process GO:0006801 15 14 0,000 0,10638039 0,14841715 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,10638039 0,14830488 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,10638039 0,14819278 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,10638039 0,14808085 ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,10638039 0,14796909 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 0,000 0,10638039 0,1478575 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,10638039 0,14774608 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,10638039 0,14763483 GO:0033189|response to vitamin A, ! lysosome organization GO:0007040 14 14 0,000 0,10638039 0,14752374 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,10638039 0,14741282 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,10638039 0,14730207 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,10638039 0,14719148 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,10638039 0,14708106 ! peptide cross-linking GO:0018149 14 14 0,000 0,10638039 0,1469708 ! regulation of behavior GO:0050795 14 14 0,000 0,10638039 0,14686071 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,10638039 0,14675079 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,10638039 0,14664103 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,10638039 0,14653143 ! formation of primary germ layer GO:0001704 14 14 0,000 0,10638039 0,14642199 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,10638039 0,14631272 ! collagen fibril organization GO:0030199 14 14 0,000 0,10638039 0,14620362 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,10638039 0,14609467 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,10638039 0,14598589 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,10638039 0,14587727 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,10638039 0,14576881 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,10638039 0,14566051 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,10638039 0,14555238 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,10638039 0,1454444 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,10638039 0,14533658 ! positive regulation of transport GO:0051050 71 70 1,000 0,1074751 0,14672341 ! cell part morphogenesis GO:0032990 75 70 1,000 0,1074751 0,14661481 ! muscle tissue development GO:0060537 72 70 1,000 0,1074751 0,14650637 ! translational elongation GO:0006414 71 71 1,000 0,11004417 0,14989757 ! calcium ion homeostasis GO:0055074 71 71 1,000 0,11004417 0,14978686 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 1,000 0,11004417 0,14967632 ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,11004417 0,14956593 ! secretion by cell GO:0032940 75 72 1,000 0,11262966 0,15296718 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,11262966 0,15285454 ! sensory organ development GO:0007423 72 72 1,000 0,11262966 0,15274206 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,11353871 0,15386165 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,11353871 0,1537486 ! positive regulation of ossification GO:0045778 15 15 0,000 0,11353871 0,15363572 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,11353871 0,153523 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,11353871 0,15341045 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,11353871 0,15329806 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,11353871 0,15318583 ! response to vitamin GO:0033273 15 15 0,000 0,11353871 0,15307377 ! regulation of transcription factor import into nucleus GO:0042990 15 15 0,000 0,11353871 0,15296188 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,11353871 0,15285015 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,11353871 0,15273858 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,11353871 0,15262717 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,11353871 0,15251592 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,11353871 0,15240484 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,11353871 0,15229392 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,11353871 0,15218316 ! heme metabolic process GO:0042168 15 15 0,000 0,11353871 0,15207256 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,11353871 0,15196213 ! chromosome condensation GO:0030261 15 15 0,000 0,11353871 0,15185185 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,11353871 0,15174173 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,11353871 0,15163177 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,11353871 0,15152198 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,11353871 0,15141234 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,11353871 0,15130286 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,11353871 0,15119353 ! phospholipid transport GO:0015914 15 15 0,000 0,11353871 0,15108437 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,11353871 0,15097536 ! glutathione metabolic process GO:0006749 16 15 0,000 0,11353871 0,15086651 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,11353871 0,15075782 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,11353871 0,15064928 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,11353871 0,1505409 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,11353871 0,15043267 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,11353871 0,1503246 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,11353871 0,15021669 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,11353871 0,15010893 ! protein homooligomerization GO:0051260 15 15 0,000 0,11353871 0,15000133 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,11353871 0,14989387 ! response to oxidative stress GO:0006979 76 75 1,000 0,12048052 0,1589446 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,12064073 0,15904211 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,12064073 0,15892843 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,12064073 0,15881491 ! circadian rhythm GO:0007623 16 16 0,000 0,12064073 0,15870155 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,12064073 0,15858835 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,12064073 0,15847532 GO:0051785|positive regulation of nuclear division, ! vacuole organization GO:0007033 16 16 0,000 0,12064073 0,15836244 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,12064073 0,15824973 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,12064073 0,15813718 ! vesicle targeting GO:0006903 17 16 0,000 0,12064073 0,15802479 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,12064073 0,15791255 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,12064073 0,15780048 ! iron ion homeostasis GO:0055072 16 16 0,000 0,12064073 0,15768856 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,12064073 0,15757681 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,12064073 0,15746521 ! cell fate specification GO:0001708 16 16 0,000 0,12064073 0,15735377 ! pentose metabolic process GO:0019321 16 16 0,000 0,12064073 0,15724248 ! fatty acid transport GO:0015908 16 16 0,000 0,12064073 0,15713136 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,12064073 0,15702039 ! cofactor catabolic process GO:0051187 16 16 0,000 0,12064073 0,15690958 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,12064073 0,15679892 ! polyol metabolic process GO:0019751 16 16 0,000 0,12064073 0,15668842 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,12064073 0,15657808 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,12064073 0,15646789 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,12064073 0,15635786 GO:0033013|tetrapyrrole metabolic process, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,12064073 0,15624798 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,12064073 0,15613825 ! regulation of coagulation GO:0050818 17 16 0,000 0,12064073 0,15602868 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,12312759 0,15913335 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,12578907 0,16245918 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,12578907 0,16234541 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,12768688 0,16467944 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,12768688 0,16456428 ! positive regulation of cell adhesion GO:0045785 17 17 0,000 0,12768688 0,16444928 ! myelination GO:0042552 17 17 0,000 0,12768688 0,16433444 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,12768688 0,16421977 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,12768688 0,16410525 ! leukocyte adhesion GO:0007159 17 17 0,000 0,12768688 0,16399089 ! sensory perception of smell GO:0007608 17 17 0,000 0,12768688 0,16387669 ! tissue remodeling GO:0048771 17 17 0,000 0,12768688 0,16376265 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,12768688 0,16364876 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,12768688 0,16353504 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,12768688 0,16342147 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,12768688 0,16330807 ! neural crest cell development GO:0014032 19 17 0,000 0,12768688 0,16319482 GO:0014033|neural crest cell differentiation, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,12768688 0,16308172 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,12768688 0,16296878 ! regulation of oxidoreductase activity GO:0051341 17 17 0,000 0,12768688 0,162856 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,12768688 0,16274338 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,12768688 0,16263091 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,12768688 0,16251859 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,12768688 0,16240643 ! adult locomotory behavior GO:0008344 17 17 0,000 0,12768688 0,16229443 ! embryonic organ development GO:0048568 17 17 0,000 0,12768688 0,16218258 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,12768688 0,16207088 ! liver development GO:0001889 17 17 0,000 0,12768688 0,16195934 ! gene silencing GO:0016458 17 17 0,000 0,12768688 0,16184795 ! metal ion homeostasis GO:0055065 78 78 1,000 0,12846455 0,16272176 ! nuclear transport GO:0051169 79 79 1,000 0,13115366 0,16601387 GO:0006913|nucleocytoplasmic transport, ! neuron projection development GO:0031175 85 80 1,000 0,13385603 0,16931823 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,13467759 0,1702406 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,13467759 0,17012392 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,13467759 0,17000739 ! meiosis I GO:0007127 18 18 0,000 0,13467759 0,16989103 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,13467759 0,16977483 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,13467759 0,16965878 ! response to calcium ion GO:0051592 18 18 0,000 0,13467759 0,16954289 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,13467759 0,16942716 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,13467759 0,16931159 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,13467759 0,16919618 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,13467759 0,16908092 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,13467759 0,16896582 ! ceramide metabolic process GO:0006672 18 18 0,000 0,13467759 0,16885088 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,13467759 0,1687361 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,13467759 0,16862146 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,13467759 0,16850699 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,13467759 0,16839267 ! ensheathment of neurons GO:0007272 18 18 0,000 0,13467759 0,16827851 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,13467759 0,1681645 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,13467759 0,16805064 ! lipid catabolic process GO:0016042 82 81 1,000 0,13657127 0,17029827 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,14161328 0,17646604 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,14161328 0,17634681 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,14161328 0,17622774 ! feeding behavior GO:0007631 19 19 0,000 0,14161328 0,17610883 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,14161328 0,17599007 ! peroxisome organization GO:0007031 19 19 0,000 0,14161328 0,17587148 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,14161328 0,17575305 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,14161328 0,17563478 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,14161328 0,17551666 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,14161328 0,17539871 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,14161328 0,17528091 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,14161328 0,17516328 ! peripheral nervous system development GO:0007422 19 19 0,000 0,14161328 0,17504579 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,14161328 0,17492847 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,14161328 0,17481131 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,14161328 0,1746943 ! eye morphogenesis GO:0048592 19 19 0,000 0,14161328 0,17457744 ! regulation of cell shape GO:0008360 21 19 0,000 0,14161328 0,17446075 ! placenta development GO:0001890 19 19 0,000 0,14161328 0,17434421 ! vesicle localization GO:0051648 20 19 0,000 0,14161328 0,17422782 ! ncRNA processing GO:0034470 83 83 1,000 0,14203892 0,17463491 ! blood vessel morphogenesis GO:0048514 84 83 1,000 0,14203892 0,17451849 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 0,14755373 0,18117357 ! regulation of cellular localization GO:0060341 86 85 1,000 0,14755373 0,18105295 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,14755373 0,18093248 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,14849439 0,18196487 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,14849439 0,18184396 ! negative regulation of binding GO:0051100 21 20 0,000 0,14849439 0,18172321 ! organic ether metabolic process GO:0018904 20 20 0,000 0,14849439 0,18160263 GO:0006662|glycerol ether metabolic process, ! nucleus organization GO:0006997 20 20 0,000 0,14849439 0,1814822 ! phagocytosis GO:0006909 21 20 0,000 0,14849439 0,18136193 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,14849439 0,18124183 ! protein targeting to membrane GO:0006612 22 20 0,000 0,14849439 0,18112188 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,14849439 0,18100209 ! chromatin remodeling GO:0006338 20 20 0,000 0,14849439 0,18088246 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,14849439 0,18076298 ! lipid oxidation GO:0034440 20 20 0,000 0,14849439 0,18064367 GO:0019395|fatty acid oxidation, ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,14849439 0,18052451 ! RNA modification GO:0009451 20 20 0,000 0,14849439 0,18040551 ! single fertilization GO:0007338 21 20 0,000 0,14849439 0,18028667 ! regulation of B cell activation GO:0050864 20 20 0,000 0,14849439 0,18016798 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 1,000 0,15032794 0,18227262 ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,15532133 0,18820329 ! mRNA catabolic process GO:0006402 21 21 0,000 0,15532133 0,18807964 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,15532133 0,18795615 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,15532133 0,18783281 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,15532133 0,18770965 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,15532133 0,18758664 ! ear morphogenesis GO:0042471 21 21 0,000 0,15532133 0,18746379 ! organic anion transport GO:0015711 21 21 0,000 0,15532133 0,18734111 ! cholesterol transport GO:0030301 21 21 0,000 0,15532133 0,18721858 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,15532133 0,18709622 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,15532133 0,18697401 GO:0032313|regulation of Rab GTPase activity, ! regulation of protein import into nucleus GO:0042306 21 21 0,000 0,15532133 0,18685196 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,15532133 0,18673008 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,15532133 0,18660835 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,15532133 0,18648678 ! chemotaxis GO:0006935 90 89 1,000 0,15871366 0,19043572 GO:0042330|taxis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,15871366 0,19031182 ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 0,16152881 0,19356151 ! brain development GO:0007420 91 90 1,000 0,16152881 0,19343574 ! RNA export from nucleus GO:0006405 22 22 0,000 0,16209452 0,19398714 ! sister chromatid segregation GO:0000819 22 22 0,000 0,16209452 0,19386126 ! regulation of ion transport GO:0043269 22 22 0,000 0,16209452 0,19373554 ! odontogenesis GO:0042476 22 22 0,000 0,16209452 0,19360998 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,16209452 0,19348459 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,16209452 0,19335935 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,16209452 0,19323428 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,16209452 0,19310937 ! spindle organization GO:0007051 22 22 0,000 0,16209452 0,19298463 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,16209452 0,19286004 ! cell chemotaxis GO:0060326 23 22 0,000 0,16209452 0,19273561 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,16209452 0,19261135 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,16209452 0,19248724 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,16209452 0,1923633 ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,16209452 0,19223951 ! detection of external stimulus GO:0009581 23 22 0,000 0,16209452 0,19211589 ! neuron migration GO:0001764 22 22 0,000 0,16209452 0,19199242 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,16209452 0,19186911 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,16209452 0,19174596 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,16209452 0,19162297 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,16209452 0,19150013 ! aerobic respiration GO:0009060 22 22 0,000 0,16209452 0,19137745 ! cytokine production GO:0001816 22 22 0,000 0,16209452 0,19125493 ! cytokinesis GO:0000910 23 22 0,000 0,16209452 0,19113257 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,16209452 0,19101036 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,16435337 0,19354841 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,16881438 0,19867491 ! viral infectious cycle GO:0019058 23 23 0,000 0,16881438 0,19854812 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,16881438 0,1984215 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,16881438 0,19829503 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,16881438 0,19816873 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,16881438 0,19804259 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,16881438 0,19791661 ! endocrine system development GO:0035270 23 23 0,000 0,16881438 0,19779079 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,16881438 0,19766512 ! lipid homeostasis GO:0055088 23 23 0,000 0,16881438 0,19753962 ! calcium-mediated signaling GO:0019722 23 23 0,000 0,16881438 0,19741428 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,16881438 0,1972891 ! pattern specification process GO:0007389 96 94 1,000 0,17288033 0,20191283 ! regulation of action potential GO:0001508 24 24 0,000 0,17548132 0,20482082 ! gliogenesis GO:0042063 24 24 0,000 0,17548132 0,20469119 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,17548132 0,20456172 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,17548132 0,20443241 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,17548132 0,20430327 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,17548132 0,20417429 ! fertilization GO:0009566 25 24 0,000 0,17548132 0,20404547 ! maintenance of protein location GO:0045185 25 24 0,000 0,17548132 0,20391682 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,17548132 0,20378833 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,18209575 0,21133657 ! negative regulation of secretion GO:0051048 26 25 0,000 0,18209575 0,21120357 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,18209575 0,21107074 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,18209575 0,21093807 ! cellular component disassembly GO:0022411 26 25 0,000 0,18209575 0,21080557 ! endosome transport GO:0016197 25 25 0,000 0,18209575 0,21067324 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,18209575 0,21054107 ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,18209575 0,21040907 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,18209575 0,21027724 ! excretion GO:0007588 25 25 0,000 0,18209575 0,21014557 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,18209575 0,21001406 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,18209575 0,20988272 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,18209575 0,20975154 ! endocytosis GO:0006897 99 98 1,000 0,18436233 0,21222971 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 1,000 0,18436233 0,21209723 ! anti-apoptosis GO:0006916 100 99 1,000 0,18725095 0,21528603 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,18865808 0,2167686 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,18865808 0,21663354 ! cellular defense response GO:0006968 26 26 0,000 0,18865808 0,21649865 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,18865808 0,21636393 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,18865808 0,21622937 ! regulation of protein secretion GO:0050708 26 26 0,000 0,18865808 0,21609499 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,18865808 0,21596077 GO:0035150|regulation of tube size, ! maintenance of location in cell GO:0051651 27 26 0,000 0,18865808 0,21582671 ! synapse organization GO:0050808 26 26 0,000 0,18865808 0,21569282 ! muscle organ development GO:0007517 102 100 1,000 0,19014624 0,21725947 ! response to other organism GO:0051707 101 100 1,000 0,19014624 0,21712486 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,1951687 0,22272193 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,1951687 0,2225841 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,1951687 0,22244645 ! peptide metabolic process GO:0006518 29 27 0,000 0,1951687 0,22230897 ! inner ear development GO:0048839 27 27 0,000 0,1951687 0,22217166 ! defense response to bacterium GO:0042742 27 27 0,000 0,1951687 0,22203451 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,1951687 0,22189754 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,1951687 0,22176073 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,20162802 0,22895899 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! regulation of muscle contraction GO:0006937 28 28 0,000 0,20162802 0,228818 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,20162802 0,22867719 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,20162802 0,22853655 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,20162802 0,22839609 ! cartilage development GO:0051216 29 28 0,000 0,20162802 0,2282558 ! positive regulation of cell cycle GO:0045787 29 29 0,000 0,20803643 0,23536596 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,20803643 0,23522156 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,20803643 0,23507734 ! leukocyte migration GO:0050900 30 29 0,000 0,20803643 0,2349333 ! regulation of epithelial cell proliferation GO:0050678 29 29 0,000 0,20803643 0,23478943 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,20803643 0,23464574 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,20803643 0,23450223 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,20803643 0,23435889 ! tRNA processing GO:0008033 29 29 0,000 0,20803643 0,23421573 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,20803643 0,23407274 ! adult behavior GO:0030534 30 29 0,000 0,20803643 0,23392992 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,20803643 0,23378728 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,20803643 0,23364482 ! transition metal ion transport GO:0000041 31 30 0,000 0,21439434 0,24063871 ! RNA catabolic process GO:0006401 30 30 0,000 0,21439434 0,24049225 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,21439434 0,24034596 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,21439434 0,24019986 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,21439434 0,24005393 ! activation of phospholipase C activity GO:0007202 30 30 0,000 0,21439434 0,23990817 GO:0010863|positive regulation of phospholipase C activity, ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,21439434 0,2397626 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,21439434 0,2396172 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,21439434 0,23947198 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,21439434 0,23932693 GO:0019724|B cell mediated immunity, ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,21439434 0,23918206 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,21439434 0,23903736 ! establishment of organelle localization GO:0051656 31 30 0,000 0,21439434 0,23889284 ! regulation of translational initiation GO:0006446 31 31 0,000 0,22070212 0,24577281 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,22070212 0,2456244 ! membrane fusion GO:0006944 31 31 0,000 0,22070212 0,24547617 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,22070212 0,24532811 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,22070212 0,24518023 ! positive regulation of phospholipase activity GO:0010518 31 31 0,000 0,22070212 0,24503253 ! ion transmembrane transport GO:0034220 31 31 0,000 0,22070212 0,24488501 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,22070212 0,24473767 ! digestion GO:0007586 31 31 0,000 0,22070212 0,2445905 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,22070212 0,24444351 ! regulation of heart contraction GO:0008016 31 31 0,000 0,22070212 0,2442967 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,22070212 0,24415006 ! camera-type eye development GO:0043010 31 31 0,000 0,22070212 0,2440036 ! extracellular matrix organization GO:0030198 31 31 0,000 0,22070212 0,24385732 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,22070212 0,24371121 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,22070212 0,24356527 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,22070212 0,24341951 ! cell redox homeostasis GO:0045454 32 32 0,000 0,22696017 0,250172 ! muscle fiber development GO:0048747 32 32 0,000 0,22696017 0,25002247 ! lipid modification GO:0030258 32 32 0,000 0,22696017 0,24987311 ! regulation of phospholipase activity GO:0010517 32 32 0,000 0,22696017 0,24972394 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,22696017 0,24957494 ! cell maturation GO:0048469 32 32 0,000 0,22696017 0,24942611 ! nuclear export GO:0051168 32 32 0,000 0,22696017 0,24927747 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,22696017 0,249129 ! positive regulation of lipase activity GO:0060193 32 32 0,000 0,22696017 0,24898071 ! maintenance of location GO:0051235 33 32 0,000 0,22696017 0,24883259 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,23316887 0,25548765 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,23316887 0,25533585 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,23316887 0,25518422 ! regulation of actin filament length GO:0030832 34 34 0,000 0,23932861 0,2617701 ! regulation of angiogenesis GO:0045765 35 34 0,000 0,23932861 0,26161484 ! muscle cell differentiation GO:0042692 35 34 0,000 0,23932861 0,26145976 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,23932861 0,26130487 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,23932861 0,26115016 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,23932861 0,26099563 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,23932861 0,26084129 ! detection of stimulus GO:0051606 36 34 0,000 0,23932861 0,26068713 ! acute inflammatory response GO:0002526 35 35 0,000 0,24543976 0,26718575 ! regulation of cellular component size GO:0032535 35 35 0,000 0,24543976 0,26702802 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,24543976 0,26687048 ! mesoderm development GO:0007498 35 35 0,000 0,24543976 0,26671313 ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,24543976 0,26655596 ! regulation of immune effector process GO:0002697 35 35 0,000 0,24543976 0,26639898 ! hydrogen transport GO:0006818 36 36 0,000 0,25150269 0,27281899 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,25150269 0,27265851 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,25150269 0,27249822 GO:0035113|embryonic appendage morphogenesis, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,25150269 0,27233811 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,25150269 0,27217819 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,25150269 0,27201847 ! regulation of lipase activity GO:0060191 36 36 0,000 0,25150269 0,27185892 ! activation of immune response GO:0002253 36 36 0,000 0,25150269 0,27169957 ! coagulation GO:0050817 39 36 0,000 0,25150269 0,2715404 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,2575178 0,27787195 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! meiosis GO:0007126 37 37 0,000 0,2575178 0,27770936 GO:0051327|M phase of meiotic cell cycle, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,2575178 0,27754696 ! eye development GO:0001654 37 37 0,000 0,2575178 0,27738474 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,2575178 0,27722272 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,2575178 0,27706089 ! adaptive immune response GO:0002250 37 37 0,000 0,2575178 0,27689924 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,26348543 0,28315081 ! neurotransmitter transport GO:0006836 40 38 0,000 0,26348543 0,28298581 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,26348543 0,28282099 ! RNA elongation GO:0006354 38 38 0,000 0,26348543 0,28265637 ! meiotic cell cycle GO:0051321 38 38 0,000 0,26348543 0,28249194 ! axon guidance GO:0007411 39 38 0,000 0,26348543 0,2823277 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,26940596 0,28850389 ! hemostasis GO:0007599 42 39 0,000 0,26940596 0,28833635 ! response to unfolded protein GO:0006986 39 39 0,000 0,26940596 0,288169 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,26940596 0,28800185 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,26940596 0,28783489 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,26940596 0,28766813 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,26940596 0,28750156 ! developmental maturation GO:0021700 39 39 0,000 0,26940596 0,28733518 ! limb development GO:0060173 39 39 0,000 0,26940596 0,287169 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,27527977 0,29326047 ! DNA catabolic process GO:0006308 41 40 0,000 0,27527977 0,29309105 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,27527977 0,29292183 ! organelle localization GO:0051640 41 40 0,000 0,27527977 0,2927528 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,28110719 0,29877772 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,28110719 0,29860551 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,28110719 0,2984335 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,28110719 0,29826169 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,28110719 0,29809008 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,28110719 0,29791867 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,28688861 0,3038711 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,28688861 0,30369656 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,28688861 0,30352222 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,28688861 0,30334808 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! forebrain development GO:0030900 43 42 0,000 0,28688861 0,30317415 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 0,000 0,28688861 0,30300041 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,29262437 0,30888128 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,29262437 0,30870447 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 0,000 0,29831483 0,31452759 ! mRNA transport GO:0051028 44 44 0,000 0,29831483 0,31434776 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,29831483 0,31416813 ! vitamin metabolic process GO:0006766 44 44 0,000 0,29831483 0,31398871 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,29831483 0,31380949 ! amine biosynthetic process GO:0009309 46 45 0,000 0,30396034 0,31956583 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,30396034 0,31938364 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,30396034 0,31920165 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 0,000 0,30396034 0,31901987 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,30396034 0,3188383 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,30956124 0,32452865 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,30956124 0,32434415 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 0,000 0,30956124 0,32415987 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,30956124 0,32397579 ! positive regulation of ligase activity GO:0051351 47 46 0,000 0,30956124 0,32379192 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,31511789 0,32941705 ! regulation of blood pressure GO:0008217 48 47 0,000 0,31511789 0,32923031 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 0,000 0,32063062 0,33480013 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,32063062 0,33461055 ! DNA recombination GO:0006310 48 48 0,000 0,32063062 0,33442119 ! ossification GO:0001503 50 49 0,000 0,32609978 0,3399332 GO:0060348|bone development, ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,32609978 0,33974104 ! response to bacterium GO:0009617 50 49 0,000 0,32609978 0,3395491 ! regulation of ligase activity GO:0051340 50 49 0,000 0,32609978 0,33935737 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,32609978 0,33916586 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,32609978 0,33897456 GO:0002696|positive regulation of leukocyte activation, ! chromatin assembly GO:0031497 50 50 0,000 0,33152571 0,34442045 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,33152571 0,34422642 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,33152571 0,34403259 ! transcription initiation GO:0006352 50 50 0,000 0,33152571 0,34383899 ! positive regulation of immune response GO:0050778 51 51 0,000 0,33690874 0,34922543 ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,33690874 0,34902912 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,33690874 0,34883304 ! RNA localization GO:0006403 52 52 0,000 0,3422492 0,35416355 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,3422492 0,3539648 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,3422492 0,35376628 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,3422492 0,35356798 ! sodium ion transport GO:0006814 53 53 0,000 0,34754743 0,35884029 ! tRNA metabolic process GO:0006399 53 53 0,000 0,34754743 0,35863937 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,34754743 0,35843868 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,34754743 0,35823821 ! regulation of T cell activation GO:0050863 53 53 0,000 0,34754743 0,35803796 ! hormone metabolic process GO:0042445 55 54 0,000 0,35280375 0,36324989 ! nucleosome organization GO:0034728 55 55 0,000 0,35801849 0,36841322 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,35801849 0,36820763 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,36319196 0,37332002 ! extracellular structure organization GO:0043062 56 56 0,000 0,36319196 0,37311192 ! ATP metabolic process GO:0046034 57 57 0,000 0,3683245 0,37817385 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,3683245 0,37796328 ! innate immune response GO:0045087 58 58 0,000 0,37341642 0,38297521 ! sterol metabolic process GO:0016125 59 59 0,000 0,37846803 0,38794026 ! potassium ion transport GO:0006813 60 60 0,000 0,38347965 0,39285881 ! cellular respiration GO:0045333 62 61 0,000 0,38845159 0,39773127 ! proteasomal protein catabolic process GO:0010498 62 61 0,000 0,38845159 0,39751043 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,38845159 0,39728983 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,39338415 0,40211148 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,39338415 0,40188858 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,39338415 0,40166593 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,39338415 0,40144352 ! regulation of secretion GO:0051046 65 63 0,000 0,39827765 0,40621235 ! negative regulation of cellular component organization GO:0051129 65 63 0,000 0,39827765 0,40598767 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,39827765 0,40576325 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,39827765 0,40553907 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,40313239 0,41025566 ! regulation of hormone levels GO:0010817 66 65 0,000 0,40794866 0,41492792 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,41272677 0,41955623 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,41272677 0,41932494 ! DNA packaging GO:0006323 66 66 0,000 0,41272677 0,41909391 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,41746702 0,42367385 ! muscle contraction GO:0006936 67 67 0,000 0,41746702 0,42344068 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,42216969 0,4279751 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,42216969 0,42773982 ! sensory perception of sound GO:0007605 71 69 0,000 0,42683508 0,43222915 GO:0050954|sensory perception of mechanical stimulus, ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,42683508 0,4319918 ! wound healing GO:0042060 74 70 0,000 0,43146349 0,43643645 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,43146349 0,43619704 GO:0016053|organic acid biosynthetic process, ! oxidative phosphorylation GO:0006119 71 71 0,000 0,43605519 0,44059744 ! regulation of cell activation GO:0050865 71 71 0,000 0,43605519 0,44035601 ! muscle system process GO:0003012 72 72 0,000 0,44061048 0,44471255 ! regulation of cytokine production GO:0001817 72 72 0,000 0,44061048 0,44446914 ! electron transport chain GO:0022900 75 74 0,000 0,44961295 0,45330233 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,44961295 0,45305449 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,45406068 0,45728625 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,45406068 0,4570365 ! regulation of immune response GO:0050776 78 78 0,000 0,46719322 0,46999842 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,47577541 0,47837102 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,4883948 0,49079151 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,49664153 0,49880672 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,50071581 0,50262485 GO:0006644|phospholipid metabolic process, ! male gamete generation GO:0048232 90 88 0,000 0,50876746 0,5104292 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,50876746 0,51015149 ! DNA replication GO:0006260 91 91 0,000 0,52060647 0,52173884 ! visual perception GO:0007601 93 92 0,000 0,5244902 0,52534535 GO:0050953|sensory perception of light stimulus, ! positive regulation of immune system process GO:0002684 92 92 0,000 0,5244902 0,52505999 ! cofactor metabolic process GO:0051186 95 94 0,000 0,53216522 0,53245412 ! blood circulation GO:0008015 99 98 0,000 0,54715215 0,54715215 GO:0003013|circulatory system process,