pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6449-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! response to UV GO:0009411 104 53 4,000 2,664E-07 6,409E-04 ! regulation of helicase activity GO:0051095 15 7 2,000 5,805E-07 6,984E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 3,000 5,721E-06 4,588E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,107E-05 6,659E-03 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 1,818E-05 8,749E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 1,846E-05 7,401E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 2,484E-05 8,537E-03 ! negative regulation of cell growth GO:0030308 132 67 3,000 2,819E-05 8,477E-03 ! negative regulation of cell size GO:0045792 134 69 3,000 3,167E-05 8,466E-03 ! protein tetramerization GO:0051262 52 24 2,000 3,252E-05 7,825E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 2,000 3,689E-05 8,069E-03 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 4,674E-05 9,371E-03 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 5,817E-05 0,01076571 ! positive regulation of helicase activity GO:0051096 11 5 1,000 6,588E-05 0,01132271 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 6,588E-05 0,01056786 ! positive regulation of glycolysis GO:0045821 14 5 1,000 6,588E-05 9,907E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 6,588E-05 9,325E-03 ! negative regulation of growth GO:0045926 155 84 3,000 6,863E-05 9,174E-03 ! male sex determination GO:0030238 15 6 1,000 9,866E-05 0,01249353 ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 9,866E-05 0,01186886 ! determination of adult lifespan GO:0008340 15 6 1,000 9,866E-05 0,01130367 ! cytoplasmic microtubule organization GO:0031122 14 6 1,000 9,866E-05 0,01078987 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 1,02E-04 0,0106742 ! negative regulation of DNA metabolic process GO:0051053 61 35 2,000 1,03E-04 0,01032899 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 1,201E-04 0,01156277 ! cell cycle arrest GO:0007050 213 100 3,000 1,352E-04 0,01250884 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,379E-04 0,01228775 ! negative regulation of DNA recombination GO:0045910 15 7 1,000 1,379E-04 0,0118489 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 1,379E-04 0,01144032 ! B cell lineage commitment GO:0002326 21 7 1,000 1,379E-04 0,01105898 ! T cell lineage commitment GO:0002360 16 7 1,000 1,379E-04 0,01070223 ! response to tumor cell GO:0002347 13 7 1,000 1,379E-04 0,01036779 ! regulation of respiratory burst GO:0060263 11 7 1,000 1,379E-04 0,01005361 ! positive regulation of ATPase activity GO:0032781 11 7 1,000 1,379E-04 9,758E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,835E-04 0,01261759 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 1,000 1,835E-04 0,0122671 GO:0016446|somatic hypermutation of immunoglobulin genes, ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 1,835E-04 0,01193555 ! ER overload response GO:0006983 12 8 1,000 1,835E-04 0,01162146 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 1,835E-04 0,01132347 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 1,835E-04 0,01104039 ! multicellular organismal aging GO:0010259 18 8 1,000 1,835E-04 0,01077111 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 1,914E-04 0,01096446 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 2,341E-04 0,01309977 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 2,341E-04 0,01280205 ! regulation of developmental growth GO:0048638 15 9 1,000 2,356E-04 0,01259638 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 2,356E-04 0,01232255 ! regulation of glycolysis GO:0006110 21 9 1,000 2,356E-04 0,01206036 ! motor axon guidance GO:0008045 16 9 1,000 2,356E-04 0,01180911 ! protein heterooligomerization GO:0051291 16 9 1,000 2,356E-04 0,0115681 ! positive regulation of cell cycle GO:0045787 89 48 2,000 2,658E-04 0,01278849 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 2,658E-04 0,01253773 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 2,94E-04 0,013603 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 2,94E-04 0,01334634 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 2,94E-04 0,01309918 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 2,94E-04 0,01286102 GO:0043470|regulation of carbohydrate catabolic process, ! localization within membrane GO:0051668 20 10 1,000 2,94E-04 0,01263135 ! histone modification GO:0016570 91 50 2,000 3E-04 0,01266508 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 3,182E-04 0,01320005 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! covalent chromatin modification GO:0016569 101 52 2,000 3,371E-04 0,01374519 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 3,587E-04 0,01438489 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 3,587E-04 0,01414908 ! regulation of intracellular pH GO:0051453 19 11 1,000 3,587E-04 0,01392087 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 1,000 3,587E-04 0,0136999 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! regulation of embryonic development GO:0045995 27 11 1,000 3,587E-04 0,01348584 ! aging GO:0007568 103 55 2,000 3,979E-04 0,01472837 ! regulation of DNA replication GO:0006275 101 56 2,000 4,196E-04 0,01529778 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 4,297E-04 0,01543243 ! virus-host interaction GO:0019048 29 12 1,000 4,297E-04 0,01520548 ! regulation of B cell proliferation GO:0030888 20 12 1,000 4,297E-04 0,01498511 ! immunoglobulin production during immune response GO:0002381 23 12 1,000 4,297E-04 0,01477104 ! histone acetylation GO:0016573 26 12 1,000 4,297E-04 0,014563 ! peptidyl-lysine modification GO:0018205 21 12 1,000 4,297E-04 0,01436073 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 4,297E-04 0,01416401 GO:0042130|negative regulation of T cell proliferation, ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 4,421E-04 0,0143752 ! positive regulation of cell migration GO:0030335 126 57 2,000 4,421E-04 0,01418354 ! integrin-mediated signaling pathway GO:0007229 135 59 2,000 4,894E-04 0,01549339 ! response to X-ray GO:0010165 25 13 1,000 5,07E-04 0,01584306 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 5,07E-04 0,01563995 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of cellular pH GO:0030641 22 13 1,000 5,07E-04 0,01544197 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 5,07E-04 0,01524895 ! regulation of calcium-mediated signaling GO:0050848 25 13 1,000 5,07E-04 0,01506069 ! DNA damage response, signal transduction GO:0042770 128 60 2,000 5,142E-04 0,01508742 ! viral reproductive process GO:0022415 126 62 2,000 5,662E-04 0,01641261 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 5,905E-04 0,01691483 ! response to gamma radiation GO:0010332 28 14 1,000 5,905E-04 0,01671583 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 5,905E-04 0,01652146 ! positive regulation of cell motion GO:0051272 146 64 2,000 6,214E-04 0,01718548 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 6,803E-04 0,01859869 ! G1/S transition checkpoint GO:0031575 40 15 1,000 6,803E-04 0,01838972 ! intermediate filament cytoskeleton organization GO:0045104 31 15 1,000 6,803E-04 0,01818539 ! histone deacetylation GO:0016575 20 15 1,000 6,803E-04 0,01798555 ! regulation of ATPase activity GO:0043462 21 15 1,000 6,803E-04 0,01779005 ! viral reproduction GO:0016032 134 68 2,000 7,419E-04 0,0191949 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 7,761E-04 0,01986551 ! intermediate filament-based process GO:0045103 32 16 1,000 7,761E-04 0,0196564 ! axon cargo transport GO:0008088 43 16 1,000 7,761E-04 0,01945164 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 7,761E-04 0,01925111 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 7,761E-04 0,01905467 ! B cell activation GO:0042113 160 71 2,000 8,415E-04 0,02044993 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 9,862E-04 0,02372898 ! neuromuscular junction development GO:0007528 34 19 1,000 1,1E-03 0,026214 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 1,000 1,1E-03 0,025957 ! protein oligomerization GO:0051259 139 78 2,000 1,106E-03 0,02582498 ! protein amino acid deacetylation GO:0006476 29 20 1,000 1,221E-03 0,02823904 ! protein amino acid acetylation GO:0006473 39 20 1,000 1,221E-03 0,02797009 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 1,221E-03 0,02770622 GO:0010675|regulation of cellular carbohydrate metabolic process, ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 1,221E-03 0,02744729 ! cellular response to starvation GO:0009267 33 20 1,000 1,221E-03 0,02719315 ! negative regulation of T cell activation GO:0050868 40 20 1,000 1,221E-03 0,02694367 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 1,221E-03 0,02669872 ! cell aging GO:0007569 44 21 1,000 1,347E-03 0,02919423 ! microtubule-based transport GO:0010970 54 22 1,000 1,479E-03 0,03177357 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 1,479E-03 0,03149239 ! vesicle docking during exocytosis GO:0006904 41 22 1,000 1,479E-03 0,03121614 ! positive regulation of B cell activation GO:0050871 38 22 1,000 1,479E-03 0,0309447 ! somatic diversification of immunoglobulins GO:0016445 50 22 1,000 1,479E-03 0,03067793 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 1,479E-03 0,03041573 ! positive regulation of DNA replication GO:0045740 43 23 1,000 1,617E-03 0,03297479 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 1,617E-03 0,03269769 ! regulation of DNA recombination GO:0000018 48 23 1,000 1,617E-03 0,03242521 ! sex determination GO:0007530 47 23 1,000 1,617E-03 0,03215723 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 1,617E-03 0,03189365 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 1,761E-03 0,03445237 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 1,761E-03 0,03417453 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 1,000 1,761E-03 0,03390113 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 1,000 1,761E-03 0,03363207 ! vesicle docking GO:0048278 47 24 1,000 1,761E-03 0,03336725 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 1,761E-03 0,03310657 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 1,761E-03 0,03284993 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 1,911E-03 0,03537242 ! myelination GO:0042552 45 25 1,000 1,911E-03 0,0351024 ! negative regulation of DNA replication GO:0008156 42 25 1,000 1,911E-03 0,03483647 ! response to starvation GO:0042594 42 25 1,000 1,911E-03 0,03457454 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 1,911E-03 0,03431652 ! negative regulation of cell development GO:0010721 73 25 1,000 1,911E-03 0,03406233 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 1,911E-03 0,03381187 ! somitogenesis GO:0001756 43 25 1,000 1,911E-03 0,03356507 ! immunoglobulin production GO:0002377 55 25 1,000 1,911E-03 0,03332184 GO:0002440|production of molecular mediator of immune response, ! cellular response to nutrient levels GO:0031669 41 25 1,000 1,911E-03 0,03308212 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 1,949E-03 0,0334963 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 2,067E-03 0,03527142 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 2,067E-03 0,03502303 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 2,067E-03 0,03477811 GO:0045936|negative regulation of phosphate metabolic process, ! somatic diversification of immune receptors GO:0002200 56 26 1,000 2,067E-03 0,0345366 ! interphase GO:0051325 213 98 2,000 2,13E-03 0,03534097 ! skeletal muscle tissue development GO:0007519 186 99 2,000 2,192E-03 0,03612879 GO:0060538|skeletal muscle organ development, ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 2,229E-03 0,03647711 ! protein amino acid acylation GO:0043543 55 27 1,000 2,229E-03 0,03623064 ! mitochondrial membrane organization GO:0007006 57 27 1,000 2,229E-03 0,03598749 ! base-excision repair GO:0006284 41 27 1,000 2,229E-03 0,03574757 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 2,229E-03 0,03551083 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 2,396E-03 0,03792722 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 2,396E-03 0,03767933 ! regulation of pH GO:0006885 43 29 1,000 2,569E-03 0,04014028 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 2,569E-03 0,03988131 ! membrane docking GO:0022406 61 30 1,000 2,748E-03 0,04238499 ! ensheathment of neurons GO:0007272 57 30 1,000 2,748E-03 0,04211503 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 2,748E-03 0,04184848 ! regulation of B cell activation GO:0050864 50 30 1,000 2,748E-03 0,04158528 ! response to ionizing radiation GO:0010212 65 32 1,000 3,123E-03 0,04696284 ! peripheral nervous system development GO:0007422 64 32 1,000 3,123E-03 0,04667115 ! positive regulation of catabolic process GO:0009896 64 32 1,000 3,123E-03 0,04638306 ! DNA damage checkpoint GO:0000077 71 33 1,000 3,319E-03 0,0489905 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 3,319E-03 0,04869177 ! mismatch repair GO:0006298 46 34 1,000 3,521E-03 0,05133545 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 3,521E-03 0,0510262 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 3,728E-03 0,05370467 ! calcium-mediated signaling GO:0019722 62 35 1,000 3,728E-03 0,053385 ! regulation of microtubule-based process GO:0032886 78 35 1,000 3,728E-03 0,05306911 ! DNA integrity checkpoint GO:0031570 75 36 1,000 3,94E-03 0,05576689 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 3,94E-03 0,05544077 ! negative regulation of cell activation GO:0050866 65 36 1,000 3,94E-03 0,05511844 ! meiosis I GO:0007127 65 37 1,000 4,159E-03 0,05783441 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 4,159E-03 0,05750203 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 4,159E-03 0,05717344 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 4,382E-03 0,05990655 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 4,382E-03 0,0595681 ! carbohydrate homeostasis GO:0033500 53 38 1,000 4,382E-03 0,05923345 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 4,382E-03 0,05890253 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 1,000 4,611E-03 0,06163835 ! segmentation GO:0035282 67 39 1,000 4,611E-03 0,06129781 ! regulation of action potential in neuron GO:0019228 73 39 1,000 4,611E-03 0,06096101 ! regulation of T cell proliferation GO:0042129 71 41 1,000 5,086E-03 0,06686761 ! T cell differentiation GO:0030217 81 41 1,000 5,086E-03 0,0665042 ! regulation of T cell differentiation GO:0045580 70 41 1,000 5,086E-03 0,06614472 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 5,331E-03 0,06896319 GO:0090047|positive regulation of transcription regulator activity, ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 1,000 5,331E-03 0,0685944 ! double-strand break repair GO:0006302 81 44 1,000 5,838E-03 0,0747152 ! B cell differentiation GO:0030183 107 44 1,000 5,838E-03 0,07431988 ! glycolysis GO:0006096 65 45 1,000 6,099E-03 0,07723813 ! response to insulin stimulus GO:0032868 95 46 1,000 6,366E-03 0,08019213 ! positive regulation of DNA binding GO:0043388 73 47 1,000 6,638E-03 0,08318097 ! JNK cascade GO:0007254 91 47 1,000 6,638E-03 0,08274998 ! mitochondrial transport GO:0006839 82 48 1,000 6,915E-03 0,08575941 ! activation of caspase activity GO:0006919 84 48 1,000 6,915E-03 0,08531962 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 6,915E-03 0,08488431 ! regulation of action potential GO:0001508 95 49 1,000 7,197E-03 0,08790034 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 7,197E-03 0,0874564 ! immunoglobulin mediated immune response GO:0016064 83 49 1,000 7,197E-03 0,08701692 GO:0019724|B cell mediated immunity, ! negative regulation of immune system process GO:0002683 95 50 1,000 7,485E-03 0,09003901 ! positive regulation of binding GO:0051099 78 51 1,000 7,777E-03 0,09309237 ! regulation of angiogenesis GO:0045765 114 52 1,000 8,075E-03 0,09617618 ! positive regulation of growth GO:0045927 90 52 1,000 8,075E-03 0,09570241 ! synapse organization GO:0050808 85 52 1,000 8,075E-03 0,09523328 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 8,377E-03 0,09832101 ! activation of phospholipase C activity GO:0007202 103 54 1,000 8,685E-03 0,10143764 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of caspase activity GO:0043280 95 55 1,000 8,998E-03 0,10458242 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 1,000 8,998E-03 0,10407962 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 8,998E-03 0,10358163 ! heart morphogenesis GO:0003007 97 55 1,000 8,998E-03 0,10308839 ! nuclear export GO:0051168 97 55 1,000 8,998E-03 0,10259982 ! skeletal muscle fiber development GO:0048741 111 56 1,000 9,315E-03 0,10572154 ! nucleotide-excision repair GO:0006289 83 56 1,000 9,315E-03 0,10522519 ! muscle fiber development GO:0048747 112 57 1,000 9,638E-03 0,10836122 ! regulation of phospholipase activity GO:0010517 106 57 1,000 9,638E-03 0,10785721 ! positive regulation of lipase activity GO:0060193 108 58 1,000 9,966E-03 0,11100694 ! regulation of protein complex assembly GO:0043254 117 61 1,000 0,01097782 0,12171724 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 0,01097782 0,12115891 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,01167673 0,12828407 ! lymphocyte mediated immunity GO:0002449 114 64 1,000 0,01203335 0,13160112 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01288345 0,1402605 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01288345 0,1396287 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01288345 0,13900256 ! neuron fate determination GO:0048664 7 5 0,000 0,01288345 0,13838201 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01288345 0,13776698 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01288345 0,13715739 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01288345 0,13655317 ! polyol transport GO:0015791 12 5 0,000 0,01288345 0,13595426 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01288345 0,13536057 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01288345 0,13477205 ! response to superoxide GO:0000303 10 5 0,000 0,01288345 0,13418862 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01288345 0,13361022 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01288345 0,13303678 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01288345 0,13246825 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01288345 0,13190456 ! female meiosis GO:0007143 7 5 0,000 0,01288345 0,13134564 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01288345 0,13079144 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01288345 0,13024189 ! cobalt ion transport GO:0006824 11 5 0,000 0,01288345 0,12969695 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01288345 0,12915654 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01288345 0,12862063 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01288345 0,12808913 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01288345 0,12756202 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01288345 0,12703922 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01288345 0,1265207 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01288345 0,12600638 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01288345 0,12549624 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01288345 0,1249902 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01288345 0,12448824 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01288345 0,12399028 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01288345 0,1234963 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01288345 0,12300623 ! negative chemotaxis GO:0050919 14 5 0,000 0,01288345 0,12252004 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01288345 0,12203768 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01288345 0,1215591 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01288345 0,12108426 ! behavioral response to pain GO:0048266 9 5 0,000 0,01288345 0,12061312 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01288345 0,12014562 ! Notch receptor processing GO:0007220 8 5 0,000 0,01288345 0,11968174 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01288345 0,11922143 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01288345 0,11876464 ! micturition GO:0060073 9 5 0,000 0,01288345 0,11831134 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01288345 0,11786149 ! copulation GO:0007620 9 5 0,000 0,01288345 0,11741504 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01288345 0,11697196 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01288345 0,11653222 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01288345 0,11609577 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01288345 0,11566258 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01288345 0,1152326 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01288345 0,11480582 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01288345 0,11438218 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01288345 0,11396166 ! grooming behavior GO:0007625 6 5 0,000 0,01288345 0,11354421 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01288345 0,11312982 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01288345 0,11271844 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01288345 0,11231004 ! response to protozoan GO:0001562 10 5 0,000 0,01288345 0,11190459 ! lymph vessel development GO:0001945 10 5 0,000 0,01288345 0,11150205 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01288345 0,1111024 ! endochondral ossification GO:0001958 16 5 0,000 0,01288345 0,11070561 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01288345 0,11031164 ! parathyroid gland development GO:0060017 13 5 0,000 0,01288345 0,10992046 ! anagen GO:0042640 6 5 0,000 0,01288345 0,10953205 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01288345 0,10914638 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01288345 0,10876341 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01288345 0,10838311 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01288345 0,10800547 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01288345 0,10763045 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01288345 0,10725803 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01288345 0,10688817 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01288345 0,10652086 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01288345 0,10615606 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01288345 0,10579376 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01288345 0,10543391 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01288345 0,10507651 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01288345 0,10472152 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01288345 0,10436892 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01288345 0,10401869 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01288345 0,1036708 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01288345 0,10332524 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01288345 0,10298196 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01288345 0,10264096 ! histidine catabolic process GO:0006548 6 5 0,000 0,01288345 0,10230221 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01288345 0,10196569 ! microvillus organization GO:0032528 7 5 0,000 0,01288345 0,10163138 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01288345 0,10129925 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01288345 0,10096929 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01288345 0,10064146 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01288345 0,10031576 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01288345 0,09999216 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01288345 0,09967065 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01288345 0,09935119 ! polyol catabolic process GO:0046174 7 5 0,000 0,01288345 0,09903377 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01288345 0,09871838 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01288345 0,09840499 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01288345 0,09809358 ! muscle cell migration GO:0014812 8 5 0,000 0,01288345 0,09778413 ! mitochondrial fission GO:0000266 8 5 0,000 0,01288345 0,09747664 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01288345 0,09717107 ! mRNA transcription GO:0009299 9 5 0,000 0,01288345 0,09686741 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01288345 0,09656564 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01288345 0,09626575 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01288345 0,09596771 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01288345 0,09567151 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01288345 0,09537714 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01288345 0,09508457 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01288345 0,09479379 ! response to food GO:0032094 6 5 0,000 0,01288345 0,09450479 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01288345 0,09421754 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01288345 0,09393203 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01288345 0,09364825 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01288345 0,09336618 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01288345 0,0930858 ! forebrain neuron development GO:0021884 13 5 0,000 0,01288345 0,0928071 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01288345 0,09253006 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01288345 0,09225467 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01288345 0,09198092 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01288345 0,09170879 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01288345 0,09143826 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01288345 0,09116933 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01288345 0,09090197 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01288345 0,09063617 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01288345 0,09037193 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01288345 0,09010922 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01288345 0,08984803 ! basic amino acid transport GO:0015802 11 5 0,000 0,01288345 0,08958835 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01288345 0,08933017 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01288345 0,08907348 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01288345 0,08881825 ! depyrimidination GO:0045008 10 5 0,000 0,01288345 0,08856449 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01288345 0,08831217 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01288345 0,08806128 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01288345 0,08781181 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01288345 0,08756376 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01288345 0,0873171 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01288345 0,08707183 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01288345 0,08682793 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01288345 0,08658539 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01288345 0,08634421 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01288345 0,08610436 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01288345 0,08586585 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01288345 0,08562865 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01288345 0,08539276 ! response to arsenic GO:0046685 10 5 0,000 0,01288345 0,08515816 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01288345 0,08492485 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01288345 0,08469282 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01288345 0,08446205 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01288345 0,08423253 ! response to cadmium ion GO:0046686 7 5 0,000 0,01288345 0,08400426 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01288345 0,08377722 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01288345 0,0835514 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01288345 0,0833268 ! decidualization GO:0046697 11 5 0,000 0,01288345 0,08310341 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01288345 0,0828812 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01288345 0,08266019 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01288345 0,08244035 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01288345 0,08222167 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01288345 0,08200416 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01288345 0,08178779 ! neural tube patterning GO:0021532 7 5 0,000 0,01288345 0,08157255 ! embryonic cleavage GO:0040016 6 5 0,000 0,01288345 0,08135845 ! peroxisome fission GO:0016559 5 5 0,000 0,01288345 0,08114547 ! histone demethylation GO:0016577 10 5 0,000 0,01288345 0,0809336 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01288345 0,08072284 ! mitotic recombination GO:0006312 9 5 0,000 0,01288345 0,08051317 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01288345 0,08030459 ! metaphase plate congression GO:0051310 7 5 0,000 0,01288345 0,08009708 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01288345 0,07989065 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01288345 0,07968527 ! enteric nervous system development GO:0048484 8 5 0,000 0,01288345 0,07948095 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01288345 0,07927767 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01288345 0,07907544 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01288345 0,07887423 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01288345 0,07867404 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01288345 0,07847486 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01288345 0,07827669 ! plasminogen activation GO:0031639 5 5 0,000 0,01288345 0,07807952 ! B cell homeostasis GO:0001782 13 5 0,000 0,01288345 0,07788334 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01288345 0,07768815 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01288345 0,07749393 ! metaphase GO:0051323 8 5 0,000 0,01288345 0,07730067 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01288345 0,07710838 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01288345 0,07691705 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01288345 0,07672666 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01288345 0,07653721 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01288345 0,0763487 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01288345 0,07616111 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01288345 0,07597444 ! response to redox state GO:0051775 5 5 0,000 0,01288345 0,07578868 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01288345 0,07560383 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01288345 0,07541988 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01288345 0,07523682 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01288345 0,07505465 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01288345 0,07487336 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01288345 0,07469294 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01288345 0,07451339 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01288345 0,0743347 ! striatum development GO:0021756 9 5 0,000 0,01288345 0,07415687 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01288345 0,07397988 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01288345 0,07380374 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01288345 0,07362843 ! glial cell migration GO:0008347 11 5 0,000 0,01288345 0,07345396 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01288345 0,07328031 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01288345 0,07310748 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01288345 0,07293546 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01288345 0,07276425 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01288345 0,07259384 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01288345 0,07242423 ! neuroprotection GO:0043526 6 5 0,000 0,01288345 0,07225541 ! neural plate development GO:0001840 8 5 0,000 0,01288345 0,07208737 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01288345 0,07192012 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01288345 0,07175364 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01288345 0,07158792 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01288345 0,07142297 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01288345 0,07125878 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01288345 0,07109535 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01288345 0,07093266 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01288345 0,07077071 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01288345 0,0706095 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01288345 0,07044902 ! spindle assembly GO:0051225 6 5 0,000 0,01288345 0,07028928 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01288345 0,07013025 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01288345 0,06997194 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01288345 0,06981435 ! drug metabolic process GO:0017144 6 5 0,000 0,01288345 0,06965746 ! stem cell division GO:0017145 11 5 0,000 0,01288345 0,06950128 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01288345 0,0693458 ! organ regeneration GO:0031100 7 5 0,000 0,01288345 0,06919101 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01288345 0,06903691 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01288345 0,06888349 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01288345 0,06873076 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 0,01313158 0,06989953 ! activation of MAPK activity GO:0000187 115 67 1,000 0,01313158 0,06974523 ! lung development GO:0030324 144 67 1,000 0,01313158 0,0695916 ! hexose catabolic process GO:0019320 104 67 1,000 0,01313158 0,06943866 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,01313158 0,06928638 ! adaptive immune response GO:0002250 119 67 1,000 0,01313158 0,06913477 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of kinase activity GO:0033673 131 68 1,000 0,01350703 0,07095613 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,01350703 0,07080154 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01350703 0,07064762 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,01388711 0,07247806 ! respiratory tube development GO:0030323 150 70 1,000 0,01427181 0,07432461 ! regulation of caspase activity GO:0043281 122 72 1,000 0,01505494 0,07823367 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,01505494 0,07806506 ! respiratory system development GO:0060541 153 72 1,000 0,01505494 0,07789718 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,0154404 0,07972019 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,0154404 0,07954948 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,0154404 0,07937951 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,0154404 0,07921025 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,0154404 0,07904172 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,0154404 0,07887391 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,0154404 0,0787068 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,0154404 0,0785404 ! sleep GO:0030431 13 6 0,000 0,0154404 0,0783747 ! response to oxygen radical GO:0000305 11 6 0,000 0,0154404 0,0782097 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,0154404 0,0780454 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,0154404 0,07788178 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,0154404 0,07771885 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,0154404 0,0775566 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,0154404 0,07739502 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,0154404 0,07723412 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,0154404 0,07707388 ! forebrain regionalization GO:0021871 8 6 0,000 0,0154404 0,07691431 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,0154404 0,07675539 ! male meiosis GO:0007140 7 6 0,000 0,0154404 0,07659713 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,0154404 0,07643953 ! response to zinc ion GO:0010043 9 6 0,000 0,0154404 0,07628257 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,0154404 0,07612625 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,0154404 0,07597057 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,0154404 0,07581553 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,0154404 0,07566112 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,0154404 0,07550734 ! malate metabolic process GO:0006108 11 6 0,000 0,0154404 0,07535418 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,0154404 0,07520164 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,0154404 0,07504972 ! protein refolding GO:0042026 15 6 0,000 0,0154404 0,07489841 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,0154404 0,0747477 ! opsonization GO:0008228 8 6 0,000 0,0154404 0,07459761 ! mating behavior GO:0007617 7 6 0,000 0,0154404 0,07444811 ! neuron remodeling GO:0016322 15 6 0,000 0,0154404 0,07429922 ! erythrocyte maturation GO:0043249 7 6 0,000 0,0154404 0,07415092 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,0154404 0,07400321 ! equilibrioception GO:0050957 14 6 0,000 0,0154404 0,07385608 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,0154404 0,07370954 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,0154404 0,07356358 ! photoreceptor cell development GO:0042461 10 6 0,000 0,0154404 0,0734182 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,0154404 0,07327339 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,0154404 0,07312915 ! response to interferon-gamma GO:0034341 15 6 0,000 0,0154404 0,07298548 ! toxin metabolic process GO:0009404 11 6 0,000 0,0154404 0,07284237 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,0154404 0,07269982 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,0154404 0,07255783 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,0154404 0,07241639 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,0154404 0,0722755 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,0154404 0,07213516 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,0154404 0,07199537 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,0154404 0,07185611 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,0154404 0,07171739 ! thymic T cell selection GO:0045061 12 6 0,000 0,0154404 0,07157921 ! protein lipoylation GO:0009249 10 6 0,000 0,0154404 0,07144156 ! cysteine metabolic process GO:0006534 10 6 0,000 0,0154404 0,07130443 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,0154404 0,07116783 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,0154404 0,07103176 ! glutamate catabolic process GO:0006538 10 6 0,000 0,0154404 0,0708962 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,0154404 0,07076116 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,0154404 0,07062663 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,0154404 0,07049262 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,0154404 0,07035911 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,0154404 0,0702261 ! hyperosmotic response GO:0006972 9 6 0,000 0,0154404 0,0700936 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,0154404 0,0699616 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,0154404 0,06983009 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,0154404 0,06969908 ! urea metabolic process GO:0019627 7 6 0,000 0,0154404 0,06956856 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,0154404 0,06943852 ! neutrophil activation GO:0042119 8 6 0,000 0,0154404 0,06930897 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,0154404 0,06917991 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,0154404 0,06905132 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,0154404 0,06892321 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,0154404 0,06879557 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,0154404 0,06866841 ! neuron apoptosis GO:0051402 9 6 0,000 0,0154404 0,06854171 ! nucleoside salvage GO:0043174 9 6 0,000 0,0154404 0,06841549 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,0154404 0,06828972 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,0154404 0,06816442 ! T cell mediated immunity GO:0002456 16 6 0,000 0,0154404 0,06803958 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,0154404 0,06791519 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,0154404 0,06779126 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,0154404 0,06766778 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0154404 0,06754474 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,0154404 0,06742216 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,0154404 0,06730002 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,0154404 0,06717832 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,0154404 0,06705706 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,0154404 0,06693623 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,0154404 0,06681584 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,0154404 0,06669589 ! establishment of spindle localization GO:0051293 12 6 0,000 0,0154404 0,06657636 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,0154404 0,06645726 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,0154404 0,06633859 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,0154404 0,06622034 ! neural nucleus development GO:0048857 14 6 0,000 0,0154404 0,06610251 ! response to UV-C GO:0010225 11 6 0,000 0,0154404 0,0659851 ! astrocyte development GO:0014002 15 6 0,000 0,0154404 0,0658681 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,0154404 0,06575152 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,0154404 0,06563535 ! interaction with symbiont GO:0051702 13 6 0,000 0,0154404 0,06551959 ! regulation of dendrite development GO:0050773 16 6 0,000 0,0154404 0,06540424 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,0154404 0,0652893 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,0154404 0,06517475 ! response to copper ion GO:0046688 10 6 0,000 0,0154404 0,06506061 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,0154404 0,06494687 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,0154404 0,06483352 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0154404 0,06472057 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,0154404 0,06460802 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,0154404 0,06449585 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,0154404 0,06438407 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0154404 0,06427268 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,0154404 0,06416167 ! hair follicle maturation GO:0048820 7 6 0,000 0,0154404 0,06405105 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,0154404 0,06394081 ! Schwann cell development GO:0014044 15 6 0,000 0,0154404 0,06383094 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,0154404 0,06372146 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,0154404 0,06361234 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,0154404 0,06350361 ! subpallium development GO:0021544 10 6 0,000 0,0154404 0,06339524 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,0154404 0,06328724 ! histone ubiquitination GO:0016574 8 6 0,000 0,0154404 0,06317961 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,0154404 0,06307234 ! maintenance of organ identity GO:0048496 9 6 0,000 0,0154404 0,06296544 ! G2 phase GO:0051319 16 6 0,000 0,0154404 0,0628589 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,0154404 0,06275272 ! establishment of planar polarity GO:0001736 7 6 0,000 0,0154404 0,0626469 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,0154404 0,06254143 ! membrane to membrane docking GO:0022614 14 6 0,000 0,0154404 0,06243632 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,0154404 0,06233156 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,0154404 0,06222715 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,0154404 0,06212309 ! receptor internalization GO:0031623 10 6 0,000 0,0154404 0,06201938 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,0154404 0,06191602 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,0154404 0,06181299 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0154404 0,06171031 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,0154404 0,06160798 ! protein deubiquitination GO:0016579 14 6 0,000 0,0154404 0,06150598 ! protein destabilization GO:0031648 9 6 0,000 0,0154404 0,06140431 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,0154404 0,06130299 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,0154404 0,06120199 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,0154404 0,06110133 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,0154404 0,061001 ! progesterone metabolic process GO:0042448 10 6 0,000 0,0154404 0,060901 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,0154404 0,06080132 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,0154404 0,06070198 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,0154404 0,06060295 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,0154404 0,06050425 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,0154404 0,06040587 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,0154404 0,06030781 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,0154404 0,06021006 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,0154404 0,06011264 ! catecholamine transport GO:0051937 9 6 0,000 0,0154404 0,06001552 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,0154404 0,05991872 ! sensory cilium assembly GO:0035058 10 6 0,000 0,0154404 0,05982224 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,0154404 0,05972606 ! maternal placenta development GO:0001893 12 6 0,000 0,0154404 0,05963019 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,0154404 0,05953463 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,0154404 0,05943937 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,0154404 0,05934442 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,0154404 0,05924978 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,0154404 0,05915543 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,0154404 0,05906138 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,0154404 0,05896763 ! axon guidance GO:0007411 139 73 1,000 0,01545333 0,05892346 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,01585622 0,06036403 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 121 74 1,000 0,01585622 0,06026867 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 1,000 0,01585622 0,06017361 ! leukocyte mediated immunity GO:0002443 128 74 1,000 0,01585622 0,06007885 ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,01585622 0,05998439 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,0162636 0,06142893 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,0162636 0,06133265 ! meiotic cell cycle GO:0051321 122 75 1,000 0,0162636 0,06123667 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,0162636 0,06114099 ! monosaccharide catabolic process GO:0046365 115 76 1,000 0,01667545 0,06259146 ! regulation of catabolic process GO:0009894 161 76 1,000 0,01667545 0,06249396 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,01709173 0,06395442 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,01793749 0,0670149 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,01793749 0,066911 ! tRNA transcription GO:0009304 14 7 0,000 0,01799082 0,06700606 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01799082 0,0669025 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01799082 0,06679925 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01799082 0,06669633 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01799082 0,06659372 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01799082 0,06649142 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01799082 0,06638944 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01799082 0,06628777 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01799082 0,06618642 ! prostate gland development GO:0030850 13 7 0,000 0,01799082 0,06608537 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01799082 0,06598463 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01799082 0,06588419 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01799082 0,06578407 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01799082 0,06568424 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01799082 0,06558472 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01799082 0,0654855 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01799082 0,06538658 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01799082 0,06528796 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01799082 0,06518963 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01799082 0,0650916 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01799082 0,06499387 ! glycolipid transport GO:0046836 10 7 0,000 0,01799082 0,06489643 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01799082 0,06479928 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,01799082 0,06470242 ! neuron adhesion GO:0007158 12 7 0,000 0,01799082 0,06460584 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01799082 0,06450956 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01799082 0,06441357 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01799082 0,06431785 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01799082 0,06422243 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01799082 0,06412728 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01799082 0,06403242 ! mRNA stabilization GO:0048255 18 7 0,000 0,01799082 0,06393784 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01799082 0,06384353 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01799082 0,06374951 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01799082 0,06365576 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01799082 0,06356228 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01799082 0,06346909 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01799082 0,06337616 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01799082 0,0632835 ! lipoprotein transport GO:0042953 14 7 0,000 0,01799082 0,06319112 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01799082 0,063099 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01799082 0,06300716 ! rhythmic behavior GO:0007622 15 7 0,000 0,01799082 0,06291558 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01799082 0,06282426 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01799082 0,06273321 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01799082 0,06264243 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01799082 0,0625519 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01799082 0,06246164 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01799082 0,06237164 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01799082 0,06228189 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01799082 0,06219241 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01799082 0,06210318 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01799082 0,06201421 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01799082 0,06192549 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01799082 0,06183702 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01799082 0,06174881 ! spinal cord patterning GO:0021511 13 7 0,000 0,01799082 0,06166085 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01799082 0,06157314 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01799082 0,06148568 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01799082 0,06139846 ! adrenal gland development GO:0030325 17 7 0,000 0,01799082 0,0613115 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01799082 0,06122478 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01799082 0,0611383 ! ovulation GO:0030728 9 7 0,000 0,01799082 0,06105207 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01799082 0,06096608 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01799082 0,06088033 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01799082 0,06079483 ! microtubule nucleation GO:0007020 20 7 0,000 0,01799082 0,06070956 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01799082 0,06062453 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01799082 0,06053974 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01799082 0,06045519 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01799082 0,06037087 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01799082 0,06028679 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01799082 0,06020294 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01799082 0,06011933 ! galactose metabolic process GO:0006012 13 7 0,000 0,01799082 0,06003594 ! vesicle fusion GO:0006906 17 7 0,000 0,01799082 0,05995279 ! response to dietary excess GO:0002021 8 7 0,000 0,01799082 0,05986987 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01799082 0,05978718 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01799082 0,05970471 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01799082 0,05962247 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01799082 0,05954046 ! organ growth GO:0035265 15 7 0,000 0,01799082 0,05945868 ! purine salvage GO:0043101 10 7 0,000 0,01799082 0,05937711 ! nucleoside transport GO:0015858 8 7 0,000 0,01799082 0,05929578 ! parturition GO:0007567 14 7 0,000 0,01799082 0,05921466 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01799082 0,05913377 ! rRNA modification GO:0000154 14 7 0,000 0,01799082 0,05905309 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01799082 0,05897264 ! spindle checkpoint GO:0031577 15 7 0,000 0,01799082 0,0588924 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01799082 0,05881239 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01799082 0,05873259 ! macrophage differentiation GO:0030225 11 7 0,000 0,01799082 0,058653 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01799082 0,05857363 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01799082 0,05849448 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01799082 0,05841554 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01799082 0,05833681 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01799082 0,0582583 ! fibrinolysis GO:0042730 10 7 0,000 0,01799082 0,05817999 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01799082 0,0581019 ! eating behavior GO:0042755 7 7 0,000 0,01799082 0,05802402 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01799082 0,05794634 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01799082 0,05786887 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01799082 0,05779161 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01799082 0,05771455 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01799082 0,0576377 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01799082 0,05756106 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01799082 0,05748462 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01799082 0,05740838 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01799082 0,05733234 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01799082 0,0572565 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01799082 0,05718087 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01799082 0,05710543 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01799082 0,05703019 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01799082 0,05695515 ! regulation of meiosis GO:0040020 12 7 0,000 0,01799082 0,05688031 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01799082 0,05680566 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01799082 0,05673121 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01799082 0,05665696 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01799082 0,0565829 ! transcription termination GO:0006353 13 7 0,000 0,01799082 0,05650903 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01799082 0,05643535 ! anaphase GO:0051322 17 7 0,000 0,01799082 0,05636187 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01799082 0,05628858 ! axonal fasciculation GO:0007413 18 7 0,000 0,01799082 0,05621548 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01799082 0,05614256 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01799082 0,05606984 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01799082 0,0559973 ! diuresis GO:0030146 12 7 0,000 0,01799082 0,05592496 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01799082 0,05585279 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01799082 0,05578082 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01799082 0,05570903 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01799082 0,05563742 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01799082 0,055566 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01799082 0,05549476 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01799082 0,05542371 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01799082 0,05535283 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01799082 0,05528214 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01799082 0,05521163 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01799082 0,05514129 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01799082 0,05507114 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01799082 0,05500116 ! lymph node development GO:0048535 10 7 0,000 0,01799082 0,05493137 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01799082 0,05486174 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01799082 0,0547923 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01799082 0,05472303 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01799082 0,05465393 ! adult feeding behavior GO:0008343 9 7 0,000 0,01799082 0,05458501 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01799082 0,05451627 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01799082 0,05444769 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01799082 0,05437929 ! muscle adaptation GO:0043500 14 7 0,000 0,01799082 0,05431106 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01799082 0,054243 ! retina homeostasis GO:0001895 12 7 0,000 0,01799082 0,05417511 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01799082 0,0541074 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01799082 0,05403985 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01799082 0,05397246 ! protein prenylation GO:0018342 18 7 0,000 0,01799082 0,05390525 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01799082 0,0538382 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01799082 0,05377132 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01799082 0,05370461 ! protein import into nucleus GO:0006606 158 80 1,000 0,01836692 0,05475937 ! T cell activation GO:0042110 168 81 1,000 0,01880069 0,05598325 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,01880069 0,05591405 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 0,01880069 0,05584502 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,01880069 0,05577616 ! nuclear import GO:0051170 161 81 1,000 0,01880069 0,05570747 ! response to drug GO:0042493 143 82 1,000 0,01923877 0,05693541 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,01923877 0,05686546 ! response to oxygen levels GO:0070482 176 83 1,000 0,01968114 0,05810162 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02053472 0,06054722 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02053472 0,06047311 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02053472 0,06039918 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02053472 0,06032543 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02053472 0,06025187 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02053472 0,06017848 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02053472 0,06010527 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02053472 0,06003224 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02053472 0,05995938 ! meiotic prophase I GO:0007128 13 8 0,000 0,02053472 0,0598867 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02053472 0,0598142 ! oligopeptide transport GO:0006857 15 8 0,000 0,02053472 0,05974187 ! UTP metabolic process GO:0046051 8 8 0,000 0,02053472 0,05966972 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02053472 0,05959774 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02053472 0,05952594 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02053472 0,05945431 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02053472 0,05938285 ! succinate metabolic process GO:0006105 14 8 0,000 0,02053472 0,05931156 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02053472 0,05924044 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02053472 0,0591695 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02053472 0,05909872 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02053472 0,05902811 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02053472 0,05895767 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02053472 0,0588874 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02053472 0,0588173 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02053472 0,05874736 ! reflex GO:0060004 16 8 0,000 0,02053472 0,05867759 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02053472 0,05860798 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02053472 0,05853854 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02053472 0,05846927 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02053472 0,05840015 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02053472 0,0583312 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02053472 0,05826242 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02053472 0,05819379 ! pigment granule organization GO:0048753 16 8 0,000 0,02053472 0,05812533 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02053472 0,05805703 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02053472 0,05798889 ! histidine metabolic process GO:0006547 16 8 0,000 0,02053472 0,0579209 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02053472 0,05785308 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02053472 0,05778542 ! glycine catabolic process GO:0006546 13 8 0,000 0,02053472 0,05771791 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02053472 0,05765056 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02053472 0,05758337 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02053472 0,05751633 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02053472 0,05744945 ! melanin metabolic process GO:0006582 15 8 0,000 0,02053472 0,05738273 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02053472 0,05731616 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02053472 0,05724975 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02053472 0,05718348 ! macrophage activation GO:0042116 12 8 0,000 0,02053472 0,05711738 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02053472 0,05705142 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02053472 0,05698562 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02053472 0,05691997 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02053472 0,05685447 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02053472 0,05678912 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02053472 0,05672392 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02053472 0,05665887 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02053472 0,05659396 ! osteoblast development GO:0002076 16 8 0,000 0,02053472 0,05652921 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02053472 0,05646461 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02053472 0,05640015 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02053472 0,05633584 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02053472 0,05627167 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02053472 0,05620766 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02053472 0,05614378 ! response to UV-B GO:0010224 16 8 0,000 0,02053472 0,05608006 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02053472 0,05601647 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02053472 0,05595304 ! intermediate filament organization GO:0045109 12 8 0,000 0,02053472 0,05588974 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02053472 0,05582659 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02053472 0,05576358 ! cellular extravasation GO:0045123 12 8 0,000 0,02053472 0,05570071 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02053472 0,05563798 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02053472 0,0555754 ! response to antibiotic GO:0046677 11 8 0,000 0,02053472 0,05551296 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02053472 0,05545065 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02053472 0,05538849 ! DNA topological change GO:0006265 12 8 0,000 0,02053472 0,05532646 ! response to tropane GO:0014073 15 8 0,000 0,02053472 0,05526458 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02053472 0,05520283 ! melanosome transport GO:0032402 13 8 0,000 0,02053472 0,05514122 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02053472 0,05507974 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02053472 0,05501841 ! mast cell activation GO:0045576 14 8 0,000 0,02053472 0,05495721 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02053472 0,05489614 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02053472 0,05483522 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02053472 0,05477442 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02053472 0,05471377 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02053472 0,05465324 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02053472 0,05459285 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02053472 0,05453259 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02053472 0,05447247 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02053472 0,05441248 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02053472 0,05435262 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02053472 0,05429289 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02053472 0,05423329 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02053472 0,05417383 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02053472 0,05411449 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02053472 0,05405528 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02053472 0,05399621 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02053472 0,05393726 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02053472 0,05387844 ! hormone catabolic process GO:0042447 17 8 0,000 0,02053472 0,05381975 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02053472 0,05376119 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02053472 0,05370275 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02053472 0,05364444 ! ATP catabolic process GO:0006200 11 8 0,000 0,02053472 0,05358626 ! blastocyst growth GO:0001832 19 8 0,000 0,02053472 0,0535282 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02053472 0,05347027 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02053472 0,05341247 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02053472 0,05335478 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02053472 0,05329723 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02053472 0,0532398 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02053472 0,05318249 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02053472 0,0531253 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02053472 0,05306824 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02053472 0,0530113 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02053472 0,05295448 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02053472 0,05289778 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02053472 0,05284121 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02053472 0,05278475 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02053472 0,05272842 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02053472 0,05267221 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02053472 0,05261611 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02053472 0,05256014 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,02057863 0,05261657 GO:0002696|positive regulation of leukocyte activation, ! mitochondrion organization GO:0007005 148 86 1,000 0,02103371 0,05372305 ! alcohol catabolic process GO:0046164 130 86 1,000 0,02103371 0,05366608 ! protein localization in nucleus GO:0034504 176 87 1,000 0,02149298 0,05477978 ! regulation of DNA binding GO:0051101 155 88 1,000 0,02195641 0,05590172 ! gland development GO:0048732 206 88 1,000 0,02195641 0,05584263 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,02242398 0,0569716 ! ossification GO:0001503 188 90 1,000 0,02289567 0,05810864 ! axon extension GO:0048675 15 9 0,000 0,02307211 0,05849472 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02307211 0,05843315 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02307211 0,05837171 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02307211 0,05831039 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02307211 0,0582492 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02307211 0,05818815 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02307211 0,05812722 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02307211 0,05806641 ! phosphate transport GO:0006817 19 9 0,000 0,02307211 0,05800574 ! reproductive behavior GO:0019098 19 9 0,000 0,02307211 0,05794519 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02307211 0,05788477 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02307211 0,05782447 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02307211 0,0577643 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02307211 0,05770425 ! GTP metabolic process GO:0046039 9 9 0,000 0,02307211 0,05764433 ! RNA methylation GO:0001510 15 9 0,000 0,02307211 0,05758454 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02307211 0,05752486 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,02307211 0,05746531 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02307211 0,05740589 ! artery development GO:0060840 24 9 0,000 0,02307211 0,05734658 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02307211 0,0572874 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02307211 0,05722834 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02307211 0,0571694 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02307211 0,05711059 ! chemosensory behavior GO:0007635 20 9 0,000 0,02307211 0,05705189 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02307211 0,05699332 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02307211 0,05693486 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02307211 0,05687653 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02307211 0,05681831 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02307211 0,05676022 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02307211 0,05670224 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02307211 0,05664438 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02307211 0,05658664 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02307211 0,05652901 ! protein targeting to ER GO:0045047 22 9 0,000 0,02307211 0,05647151 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02307211 0,05641412 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02307211 0,05635684 ! T cell selection GO:0045058 23 9 0,000 0,02307211 0,05629969 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 0,000 0,02307211 0,05624265 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02307211 0,05618572 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02307211 0,05612891 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02307211 0,05607221 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02307211 0,05601563 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02307211 0,05595917 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02307211 0,05590281 ! mannose metabolic process GO:0006013 13 9 0,000 0,02307211 0,05584657 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02307211 0,05579044 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02307211 0,05573443 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02307211 0,05567853 ! receptor clustering GO:0043113 18 9 0,000 0,02307211 0,05562274 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02307211 0,05556706 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02307211 0,05551149 ! ruffle organization GO:0031529 15 9 0,000 0,02307211 0,05545604 ! retinol metabolic process GO:0042572 18 9 0,000 0,02307211 0,05540069 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02307211 0,05534546 ! behavioral fear response GO:0001662 22 9 0,000 0,02307211 0,05529033 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02307211 0,05523532 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02307211 0,05518041 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02307211 0,05512561 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,02307211 0,05507092 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02307211 0,05501634 ! segment specification GO:0007379 13 9 0,000 0,02307211 0,05496187 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02307211 0,05490751 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02307211 0,05485325 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02307211 0,0547991 ! response to amine stimulus GO:0014075 13 9 0,000 0,02307211 0,05474506 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02307211 0,05469113 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02307211 0,0546373 ! erythrocyte development GO:0048821 15 9 0,000 0,02307211 0,05458357 ! gas homeostasis GO:0033483 16 9 0,000 0,02307211 0,05452995 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02307211 0,05447644 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02307211 0,05442303 ! renal water homeostasis GO:0003091 14 9 0,000 0,02307211 0,05436973 ! postreplication repair GO:0006301 22 9 0,000 0,02307211 0,05431653 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02307211 0,05426343 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02307211 0,05421044 ! icosanoid secretion GO:0032309 15 9 0,000 0,02307211 0,05415755 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02307211 0,05410477 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02307211 0,05405209 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02307211 0,05399951 ! regulation of cell division GO:0051302 15 9 0,000 0,02307211 0,05394703 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02307211 0,05389465 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02307211 0,05384238 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02307211 0,05379021 ! sterol catabolic process GO:0016127 11 9 0,000 0,02307211 0,05373813 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02307211 0,05368616 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02307211 0,05363429 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02307211 0,05358252 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02307211 0,05353085 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02307211 0,05347928 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02307211 0,05342781 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02307211 0,05337643 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02307211 0,05332516 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02307211 0,05327398 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02307211 0,05322291 ! purine base metabolic process GO:0006144 21 9 0,000 0,02307211 0,05317193 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02307211 0,05312105 ! pigment granule transport GO:0051904 17 9 0,000 0,02307211 0,05307026 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02307211 0,05301957 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02307211 0,05296898 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02307211 0,05291849 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02307211 0,05286809 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02307211 0,05281779 ! mitochondrion localization GO:0051646 15 9 0,000 0,02307211 0,05276758 ! bone development GO:0060348 189 91 1,000 0,02337145 0,05340144 ! regulation of membrane potential GO:0042391 164 93 1,000 0,0243352 0,05555075 ! regulation of T cell activation GO:0050863 158 94 1,000 0,02482312 0,05661082 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02560301 0,05833413 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02560301 0,05827894 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02560301 0,05822386 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02560301 0,05816888 ! synapsis GO:0007129 13 10 0,000 0,02560301 0,058114 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02560301 0,05805923 ! N-glycan processing GO:0006491 20 10 0,000 0,02560301 0,05800456 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02560301 0,05794999 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02560301 0,05789553 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02560301 0,05784116 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02560301 0,0577869 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02560301 0,05773275 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,02560301 0,05767869 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02560301 0,05762473 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02560301 0,05757088 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02560301 0,05751712 ! androgen metabolic process GO:0008209 17 10 0,000 0,02560301 0,05746347 ! phospholipid efflux GO:0033700 16 10 0,000 0,02560301 0,05740992 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02560301 0,05735646 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02560301 0,05730311 ! lung alveolus development GO:0048286 26 10 0,000 0,02560301 0,05724985 ! pathogenesis GO:0009405 13 10 0,000 0,02560301 0,0571967 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02560301 0,05714364 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02560301 0,05709068 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02560301 0,05703782 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02560301 0,05698505 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02560301 0,05693238 ! endoderm development GO:0007492 16 10 0,000 0,02560301 0,05687982 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02560301 0,05682734 ! arginine catabolic process GO:0006527 13 10 0,000 0,02560301 0,05677497 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02560301 0,05672269 ! proline metabolic process GO:0006560 13 10 0,000 0,02560301 0,05667051 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02560301 0,05661842 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02560301 0,05656643 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02560301 0,05651453 ! V(D)J recombination GO:0033151 28 10 0,000 0,02560301 0,05646273 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02560301 0,05641103 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02560301 0,05635941 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02560301 0,0563079 ! B cell proliferation GO:0042100 18 10 0,000 0,02560301 0,05625648 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02560301 0,05620515 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02560301 0,05615391 ! multicellular organism growth GO:0035264 18 10 0,000 0,02560301 0,05610277 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02560301 0,05605172 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02560301 0,05600076 ! epithelial cell development GO:0002064 20 10 0,000 0,02560301 0,0559499 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02560301 0,05589913 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02560301 0,05584845 ! macroautophagy GO:0016236 17 10 0,000 0,02560301 0,05579786 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02560301 0,05574737 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02560301 0,05569696 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02560301 0,05564665 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02560301 0,05559643 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02560301 0,05554629 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02560301 0,05549625 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02560301 0,0554463 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02560301 0,05539644 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02560301 0,05534667 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02560301 0,05529698 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02560301 0,05524739 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02560301 0,05519789 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02560301 0,05514847 ! response to dsRNA GO:0043331 20 10 0,000 0,02560301 0,05509914 ! DNA ligation GO:0006266 19 10 0,000 0,02560301 0,0550499 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02560301 0,05500075 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02560301 0,05495169 ! melanosome localization GO:0032400 16 10 0,000 0,02560301 0,05490271 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02560301 0,05485382 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02560301 0,05480502 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02560301 0,0547563 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02560301 0,05470767 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02560301 0,05465913 ! mRNA cleavage GO:0006379 17 10 0,000 0,02560301 0,05461067 ! protein sumoylation GO:0016925 15 10 0,000 0,02560301 0,0545623 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02560301 0,05451402 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02560301 0,05446582 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02560301 0,0544177 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02560301 0,05436967 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02560301 0,05432173 ! salivary gland development GO:0007431 27 10 0,000 0,02560301 0,05427387 ! prophase GO:0051324 15 10 0,000 0,02560301 0,05422609 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02560301 0,0541784 ! apical protein localization GO:0045176 15 10 0,000 0,02560301 0,05413079 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02560301 0,05408327 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02560301 0,05403583 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02560301 0,05398847 ! midbrain development GO:0030901 13 10 0,000 0,02560301 0,05394119 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02560301 0,053894 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02560301 0,05384689 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02560301 0,05379986 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02560301 0,05375291 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02560301 0,05370605 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02560301 0,05365927 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02560301 0,05361257 ! detection of calcium ion GO:0005513 23 10 0,000 0,02560301 0,05356595 ! oocyte development GO:0048599 17 10 0,000 0,02560301 0,05351941 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02560301 0,05347295 ! blastocyst formation GO:0001825 17 10 0,000 0,02560301 0,05342657 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02560301 0,05338028 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02560301 0,05333406 ! activation of innate immune response GO:0002218 12 10 0,000 0,02560301 0,05328792 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02560301 0,05324187 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02560301 0,05319589 ! response to nicotine GO:0035094 20 10 0,000 0,02560301 0,05314999 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02560301 0,05310417 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02560301 0,05305843 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02560301 0,05301277 ! leukocyte differentiation GO:0002521 202 96 1,000 0,02581092 0,05339731 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02812744 0,0581397 ! respiratory burst GO:0045730 17 11 0,000 0,02812744 0,0580898 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02812744 0,05803998 ! neuron fate specification GO:0048665 17 11 0,000 0,02812744 0,05799024 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02812744 0,0579406 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02812744 0,05789103 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02812744 0,05784155 ! thyroid gland development GO:0030878 26 11 0,000 0,02812744 0,05779216 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02812744 0,05774285 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02812744 0,05769362 ! response to pain GO:0048265 24 11 0,000 0,02812744 0,05764448 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02812744 0,05759542 ! T cell proliferation GO:0042098 26 11 0,000 0,02812744 0,05754644 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02812744 0,05749755 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02812744 0,05744874 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,02812744 0,05740001 ! bone resorption GO:0045453 16 11 0,000 0,02812744 0,05735137 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02812744 0,05730281 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02812744 0,05725433 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02812744 0,05720593 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02812744 0,05715761 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02812744 0,05710938 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02812744 0,05706123 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02812744 0,05701316 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02812744 0,05696516 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02812744 0,05691725 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,02812744 0,05686942 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02812744 0,05682168 ! UV protection GO:0009650 19 11 0,000 0,02812744 0,05677401 ! adult heart development GO:0007512 14 11 0,000 0,02812744 0,05672642 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02812744 0,05667891 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02812744 0,05663148 ! temperature homeostasis GO:0001659 17 11 0,000 0,02812744 0,05658413 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02812744 0,05653685 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02812744 0,05648966 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02812744 0,05644255 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02812744 0,05639551 ! regulation of organ growth GO:0046620 13 11 0,000 0,02812744 0,05634856 ! pigment granule localization GO:0051875 20 11 0,000 0,02812744 0,05630168 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02812744 0,05625488 ! vasoconstriction GO:0042310 18 11 0,000 0,02812744 0,05620815 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02812744 0,05616151 ! embryonic axis specification GO:0000578 18 11 0,000 0,02812744 0,05611494 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02812744 0,05606845 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02812744 0,05602203 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02812744 0,05597569 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02812744 0,05592943 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02812744 0,05588325 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02812744 0,05583714 ! zymogen activation GO:0031638 15 11 0,000 0,02812744 0,05579111 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02812744 0,05574515 ! neuroblast proliferation GO:0007405 24 11 0,000 0,02812744 0,05569927 ! nucleosome positioning GO:0016584 15 11 0,000 0,02812744 0,05565347 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02812744 0,05560774 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02812744 0,05556208 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02812744 0,0555165 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,02812744 0,055471 ! acid secretion GO:0046717 18 11 0,000 0,02812744 0,05542557 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02812744 0,05538021 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02812744 0,05533493 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02812744 0,05528972 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02812744 0,05524458 ! oocyte differentiation GO:0009994 18 11 0,000 0,02812744 0,05519952 ! thymus development GO:0048538 27 11 0,000 0,02812744 0,05515454 ! cholesterol efflux GO:0033344 19 11 0,000 0,02812744 0,05510962 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02812744 0,05506478 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02812744 0,05502001 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02812744 0,05497532 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02812744 0,05493069 ! embryonic gut development GO:0048566 15 11 0,000 0,02812744 0,05488614 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02812744 0,05484167 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02812744 0,05479726 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,02812744 0,05475292 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02812744 0,05470866 ! defense response to fungus GO:0050832 13 11 0,000 0,02812744 0,05466447 ! developmental induction GO:0031128 19 11 0,000 0,02812744 0,05462035 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,02812744 0,0545763 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02812744 0,05453232 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02812744 0,05448842 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02812744 0,05444458 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02812744 0,05440082 ! nucleus localization GO:0051647 19 11 0,000 0,02812744 0,05435712 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02812744 0,0543135 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03064541 0,05912819 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03064541 0,05908081 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03064541 0,05903351 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03064541 0,05898628 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03064541 0,05893913 ! cartilage condensation GO:0001502 20 12 0,000 0,03064541 0,05889206 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,03064541 0,05884506 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,03064541 0,05879813 ! protein complex disassembly GO:0043241 27 12 0,000 0,03064541 0,05875128 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03064541 0,0587045 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,03064541 0,0586578 ! hippocampus development GO:0021766 26 12 0,000 0,03064541 0,05861117 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,03064541 0,05856462 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03064541 0,05851814 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03064541 0,05847173 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03064541 0,0584254 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03064541 0,05837914 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03064541 0,05833296 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03064541 0,05828684 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03064541 0,0582408 ! drug transport GO:0015893 16 12 0,000 0,03064541 0,05819483 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03064541 0,05814894 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03064541 0,05810312 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03064541 0,05805737 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03064541 0,05801169 ! focal adhesion formation GO:0048041 35 12 0,000 0,03064541 0,05796608 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03064541 0,05792055 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03064541 0,05787508 ! forebrain cell migration GO:0021885 21 12 0,000 0,03064541 0,05782969 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03064541 0,05778437 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03064541 0,05773912 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03064541 0,05769394 ! entry into host cell GO:0030260 32 12 0,000 0,03064541 0,05764883 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,03064541 0,05760379 ! monoamine transport GO:0015844 18 12 0,000 0,03064541 0,05755883 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03064541 0,05751393 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03064541 0,0574691 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03064541 0,05742434 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03064541 0,05737965 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03064541 0,05733504 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03064541 0,05729049 ! protein homotetramerization GO:0051289 21 12 0,000 0,03064541 0,05724601 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03064541 0,05720159 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03064541 0,05715725 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03064541 0,05711298 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03064541 0,05706877 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03064541 0,05702464 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03064541 0,05698057 ! cranial nerve development GO:0021545 20 12 0,000 0,03064541 0,05693657 ! fucose catabolic process GO:0019317 22 12 0,000 0,03064541 0,05689264 GO:0042355|L-fucose catabolic process, ! histone methylation GO:0016571 26 12 0,000 0,03064541 0,05684877 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03064541 0,05680497 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03064541 0,05676124 ! gland morphogenesis GO:0022612 29 12 0,000 0,03064541 0,05671758 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03064541 0,05667399 ! T cell homeostasis GO:0043029 25 12 0,000 0,03064541 0,05663046 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03064541 0,056587 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03064541 0,0565436 ! spleen development GO:0048536 22 12 0,000 0,03064541 0,05650027 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03064541 0,05645701 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03064541 0,05641381 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03064541 0,05637068 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03064541 0,05632762 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03064541 0,05628462 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,03064541 0,05624169 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03064541 0,05619882 ! response to cold GO:0009409 17 12 0,000 0,03064541 0,05615602 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03064541 0,05611328 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03064541 0,05607061 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03315694 0,06061976 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,03315694 0,06057373 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03315694 0,06052777 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03315694 0,06048188 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,03315694 0,06043606 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,03315694 0,06039031 ! lipid localization GO:0010876 28 13 0,000 0,03315694 0,06034463 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,03315694 0,06029902 ! organelle fusion GO:0048284 32 13 0,000 0,03315694 0,06025347 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,03315694 0,060208 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,03315694 0,06016259 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,03315694 0,06011726 ! endocrine pancreas development GO:0031018 22 13 0,000 0,03315694 0,06007199 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,03315694 0,06002679 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,03315694 0,05998165 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,03315694 0,05993659 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03315694 0,05989159 ! methionine metabolic process GO:0006555 27 13 0,000 0,03315694 0,05984666 ! plasma membrane organization GO:0007009 24 13 0,000 0,03315694 0,0598018 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,03315694 0,059757 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,03315694 0,05971228 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,03315694 0,05966761 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,03315694 0,05962302 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,03315694 0,05957849 ! cytokine metabolic process GO:0042107 22 13 0,000 0,03315694 0,05953403 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,03315694 0,05948963 ! exocrine system development GO:0035272 32 13 0,000 0,03315694 0,05944531 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,03315694 0,05940104 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,03315694 0,05935685 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,03315694 0,05931271 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,03315694 0,05926865 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,03315694 0,05922465 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,03315694 0,05918071 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,03315694 0,05913684 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,03315694 0,05909304 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,03315694 0,0590493 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03315694 0,05900562 ! ribosome assembly GO:0042255 17 13 0,000 0,03315694 0,05896201 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,03315694 0,05891846 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,03315694 0,05887498 ! chromatin silencing GO:0006342 26 13 0,000 0,03315694 0,05883156 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,03315694 0,05878821 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03315694 0,05874492 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03315694 0,05870169 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,03315694 0,05865853 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,03315694 0,05861543 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,03315694 0,05857239 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03315694 0,05852942 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,03315694 0,05848651 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,03315694 0,05844366 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,03315694 0,05840088 ! embryonic placenta development GO:0001892 23 13 0,000 0,03315694 0,05835816 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,03315694 0,0583155 ! insulin secretion GO:0030073 23 13 0,000 0,03315694 0,0582729 ! actin filament polymerization GO:0030041 24 13 0,000 0,03315694 0,05823037 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,03315694 0,05818789 ! acrosome reaction GO:0007340 18 13 0,000 0,03315694 0,05814548 ! rRNA transcription GO:0009303 25 14 0,000 0,03566205 0,062493 ! lactation GO:0007595 26 14 0,000 0,03566205 0,06244752 ! reproductive cellular process GO:0048610 20 14 0,000 0,03566205 0,0624021 ! tRNA modification GO:0006400 20 14 0,000 0,03566205 0,06235675 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03566205 0,06231147 ! regulation of S phase GO:0033261 23 14 0,000 0,03566205 0,06226625 ! water transport GO:0006833 21 14 0,000 0,03566205 0,06222109 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,03566205 0,06217601 ! non-recombinational repair GO:0000726 25 14 0,000 0,03566205 0,06213098 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03566205 0,06208603 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03566205 0,06204113 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03566205 0,06199631 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,03566205 0,06195154 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03566205 0,06190685 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03566205 0,06186221 ! palate development GO:0060021 31 14 0,000 0,03566205 0,06181764 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,03566205 0,06177314 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03566205 0,0617287 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,03566205 0,06168432 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,03566205 0,06164001 ! arginine metabolic process GO:0006525 17 14 0,000 0,03566205 0,06159576 ! regulation of heart rate GO:0002027 24 14 0,000 0,03566205 0,06155157 ! organic alcohol transport GO:0015850 29 14 0,000 0,03566205 0,06150745 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,03566205 0,06146339 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,03566205 0,06141939 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,03566205 0,06137546 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03566205 0,06133159 ! neutral amino acid transport GO:0015804 26 14 0,000 0,03566205 0,06128778 ! L-amino acid transport GO:0015807 30 14 0,000 0,03566205 0,06124403 ! bone mineralization GO:0030282 17 14 0,000 0,03566205 0,06120035 ! stem cell development GO:0048864 43 14 0,000 0,03566205 0,06115673 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,03566205 0,06111317 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,03566205 0,06106967 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03566205 0,06102624 ! cerebellum development GO:0021549 21 14 0,000 0,03566205 0,06098286 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,03566205 0,06093955 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,03566205 0,0608963 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,03566205 0,06085311 ! cofactor transport GO:0051181 26 14 0,000 0,03566205 0,06080999 ! NADP metabolic process GO:0006739 24 14 0,000 0,03566205 0,06076692 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,03566205 0,06072391 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03566205 0,06068097 ! intestinal absorption GO:0050892 25 14 0,000 0,03566205 0,06063808 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,03566205 0,06059526 ! oxygen transport GO:0015671 21 14 0,000 0,03566205 0,0605525 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03566205 0,06050979 ! male genitalia development GO:0030539 24 14 0,000 0,03566205 0,06046715 ! regulation of RNA stability GO:0043487 32 14 0,000 0,03566205 0,06042457 ! regulation of axon extension GO:0030516 37 14 0,000 0,03566205 0,06038205 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03566205 0,06033958 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03816075 0,06452197 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03816075 0,06447666 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,03816075 0,06443141 ! superoxide anion generation GO:0042554 20 15 0,000 0,03816075 0,06438623 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,03816075 0,06434111 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,03816075 0,06429605 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,03816075 0,06425106 ! copper ion transport GO:0006825 20 15 0,000 0,03816075 0,06420613 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,03816075 0,06416126 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,03816075 0,06411645 ! sulfate transport GO:0008272 23 15 0,000 0,03816075 0,06407171 ! response to cAMP GO:0051591 22 15 0,000 0,03816075 0,06402703 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,03816075 0,06398241 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,03816075 0,06393786 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,03816075 0,06389336 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,03816075 0,06384893 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,03816075 0,06380456 ! response to hexose stimulus GO:0009746 22 15 0,000 0,03816075 0,06376025 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,03816075 0,063716 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,03816075 0,06367182 ! pituitary gland development GO:0021983 29 15 0,000 0,03816075 0,06362769 ! vesicle coating GO:0006901 33 15 0,000 0,03816075 0,06358363 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,03816075 0,06353963 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,03816075 0,06349569 ! regulation of exocytosis GO:0017157 22 15 0,000 0,03816075 0,0634518 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,03816075 0,06340798 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,03816075 0,06336422 ! regulation of vasodilation GO:0042312 26 15 0,000 0,03816075 0,06332052 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,03816075 0,06327689 ! mRNA splice site selection GO:0006376 38 15 0,000 0,03816075 0,06323331 ! tissue regeneration GO:0042246 26 15 0,000 0,03816075 0,06318979 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03816075 0,06314633 ! water homeostasis GO:0030104 27 15 0,000 0,03816075 0,06310293 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03816075 0,06305959 ! muscle maintenance GO:0046716 26 15 0,000 0,03816075 0,06301631 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,03816075 0,06297309 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,03816075 0,06292993 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03816075 0,06288682 ! heme biosynthetic process GO:0006783 29 15 0,000 0,03816075 0,06284378 ! cell killing GO:0001906 29 15 0,000 0,03816075 0,06280079 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,03816075 0,06275787 ! detection of bacterium GO:0016045 18 15 0,000 0,03816075 0,062715 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,03816075 0,06267219 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,03816075 0,06262944 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,03816075 0,06258675 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,03816075 0,06254412 ! peptide hormone processing GO:0016486 23 15 0,000 0,03816075 0,06250154 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04065306 0,06653827 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,04065306 0,06649304 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04065306 0,06644786 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,04065306 0,06640275 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,04065306 0,0663577 ! bone remodeling GO:0046849 27 16 0,000 0,04065306 0,06631271 ! filopodium assembly GO:0046847 32 16 0,000 0,04065306 0,06626779 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,04065306 0,06622292 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04065306 0,06617812 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04065306 0,06613337 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04065306 0,06608869 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,04065306 0,06604406 ! startle response GO:0001964 28 16 0,000 0,04065306 0,0659995 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,04065306 0,06595499 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,04065306 0,06591055 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,04065306 0,06586616 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,04065306 0,06582184 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04065306 0,06577758 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,04065306 0,06573337 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04065306 0,06568922 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04065306 0,06564514 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04065306 0,06560111 ! response to osmotic stress GO:0006970 25 16 0,000 0,04065306 0,06555714 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,04065306 0,06551323 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,04065306 0,06546938 ! fructose metabolic process GO:0006000 25 16 0,000 0,04065306 0,06542559 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04065306 0,06538185 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04065306 0,06533818 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,04065306 0,06529456 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04065306 0,065251 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,04065306 0,0652075 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,04065306 0,06516406 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,04065306 0,06512068 ! DNA replication initiation GO:0006270 27 16 0,000 0,04065306 0,06507735 ! neuron recognition GO:0008038 35 16 0,000 0,04065306 0,06503408 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,04065306 0,06499087 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,04065306 0,06494771 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,04065306 0,06490461 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,04065306 0,06486157 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,04065306 0,06481859 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04065306 0,06477567 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,04065306 0,0647328 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04065306 0,06468998 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04065306 0,06464723 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04065306 0,06460453 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04065306 0,06456188 ! defense response to virus GO:0051607 37 16 0,000 0,04065306 0,0645193 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,04313899 0,06841952 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,04313899 0,06837445 ! metencephalon development GO:0022037 30 17 0,000 0,04313899 0,06832943 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,04313899 0,06828448 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,04313899 0,06823958 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,04313899 0,06819475 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,04313899 0,06814997 ! signal complex assembly GO:0007172 41 17 0,000 0,04313899 0,06810526 ! endothelial cell migration GO:0043542 28 17 0,000 0,04313899 0,0680606 ! inositol metabolic process GO:0006020 28 17 0,000 0,04313899 0,068016 ! gene silencing by RNA GO:0031047 36 17 0,000 0,04313899 0,06797145 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,04313899 0,06792697 ! glial cell development GO:0021782 27 17 0,000 0,04313899 0,06788254 ! limbic system development GO:0021761 36 17 0,000 0,04313899 0,06783818 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,04313899 0,06779387 ! adult walking behavior GO:0007628 33 17 0,000 0,04313899 0,06774961 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,04313899 0,06770542 ! heart looping GO:0001947 30 17 0,000 0,04313899 0,06766128 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,04313899 0,0676172 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,04313899 0,06757318 ! myoblast differentiation GO:0045445 45 17 0,000 0,04313899 0,06752922 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,04313899 0,06748531 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,04313899 0,06744146 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,04313899 0,06739767 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,04313899 0,06735393 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,04313899 0,06731025 ! glycine metabolic process GO:0006544 28 17 0,000 0,04313899 0,06726663 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,04313899 0,06722306 ! NAD metabolic process GO:0019674 29 17 0,000 0,04313899 0,06717955 ! membrane budding GO:0006900 37 17 0,000 0,04313899 0,0671361 ! DNA integration GO:0015074 29 17 0,000 0,04313899 0,0670927 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,04313899 0,06704936 ! regulation of protein binding GO:0043393 33 17 0,000 0,04313899 0,06700607 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,04313899 0,06696284 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,04313899 0,06691967 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,04313899 0,06687655 ! genitalia development GO:0048806 30 17 0,000 0,04313899 0,06683349 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,04313899 0,06679048 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,04313899 0,06674753 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,04313899 0,06670463 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,04313899 0,06666179 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,04313899 0,066619 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,04313899 0,06657627 ! steroid catabolic process GO:0006706 31 17 0,000 0,04313899 0,0665336 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,04313899 0,06649097 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,04313899 0,06644841 ! gas transport GO:0015669 25 17 0,000 0,04313899 0,06640589 ! organic cation transport GO:0015695 31 17 0,000 0,04313899 0,06636343 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,04313899 0,06632103 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,04313899 0,06627868 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,04313899 0,06623638 ! microspike assembly GO:0030035 36 17 0,000 0,04313899 0,06619414 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,04313899 0,06615195 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,04313899 0,06610981 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,04561856 0,06986522 ! neuron maturation GO:0042551 42 18 0,000 0,04561856 0,06982078 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,04561856 0,06977639 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,04561856 0,06973206 ! phosphoinositide phosphorylation GO:0046854 33 18 0,000 0,04561856 0,06968779 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,04561856 0,06964357 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,04561856 0,06959941 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,04561856 0,0695553 ! memory GO:0007613 31 18 0,000 0,04561856 0,06951125 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04561856 0,06946725 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,04561856 0,06942332 ! patterning of blood vessels GO:0001569 39 18 0,000 0,04561856 0,06937943 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,04561856 0,0693356 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,04561856 0,06929183 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,04561856 0,06924811 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,04561856 0,06920445 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04561856 0,06916085 ! response to retinoic acid GO:0032526 26 18 0,000 0,04561856 0,06911729 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,04561856 0,0690738 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,04561856 0,06903035 ! response to fungus GO:0009620 21 18 0,000 0,04561856 0,06898697 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,04561856 0,06894363 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,04561856 0,06890035 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,04561856 0,06885713 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,04561856 0,06881396 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,04561856 0,06877084 ! vitamin transport GO:0051180 27 18 0,000 0,04561856 0,06872778 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,04561856 0,06868477 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,04561856 0,06864182 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,04561856 0,06859891 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,04561856 0,06855607 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,04561856 0,06851327 ! nerve development GO:0021675 28 18 0,000 0,04561856 0,06847053 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,04561856 0,06842784 ! protein secretion GO:0009306 39 19 0,000 0,04809179 0,07209274 ! positive regulation of translation GO:0045727 30 19 0,000 0,04809179 0,07204785 ! negative regulation of defense response GO:0031348 25 19 0,000 0,04809179 0,07200302 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,04809179 0,07195824 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,04809179 0,07191352 ! skin development GO:0043588 36 19 0,000 0,04809179 0,07186885 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,04809179 0,07182424 ! lipid phosphorylation GO:0046834 35 19 0,000 0,04809179 0,07177969 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04809179 0,07173519 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,04809179 0,07169074 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,04809179 0,07164635 ! bile acid metabolic process GO:0008206 29 19 0,000 0,04809179 0,07160201 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,04809179 0,07155773 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,04809179 0,07151351 ! cerebral cortex development GO:0021987 36 19 0,000 0,04809179 0,07146934 ! pigmentation during development GO:0048066 41 19 0,000 0,04809179 0,07142522 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,04809179 0,07138116 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,04809179 0,07133715 ! heme metabolic process GO:0042168 36 19 0,000 0,04809179 0,07129319 ! actin filament bundle formation GO:0051017 42 19 0,000 0,04809179 0,07124929 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,04809179 0,07120545 ! plasma membrane fusion GO:0045026 28 19 0,000 0,04809179 0,07116166 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,04809179 0,07111792 ! peptide cross-linking GO:0018149 37 19 0,000 0,04809179 0,07107423 ! protein export from nucleus GO:0006611 36 19 0,000 0,04809179 0,0710306 ! heart process GO:0003015 30 19 0,000 0,04809179 0,07098703 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,04809179 0,0709435 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,04809179 0,07090003 ! visual learning GO:0008542 36 19 0,000 0,04809179 0,07085662 ! cellular pigmentation GO:0033059 36 19 0,000 0,04809179 0,07081325 ! G1 phase GO:0051318 40 19 0,000 0,04809179 0,07076994 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,04809179 0,07072668 ! cell-cell junction organization GO:0045216 35 19 0,000 0,04809179 0,07068348 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,04809179 0,07064033 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,04809179 0,07059723 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,04809179 0,07055418 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,04809179 0,07051118 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,04809179 0,07046824 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,04809179 0,07042535 ! cilium assembly GO:0042384 37 19 0,000 0,04809179 0,07038251 ! peptide hormone secretion GO:0030072 31 19 0,000 0,04809179 0,07033973 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,0505587 0,07390293 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,0505587 0,07385806 ! positive regulation of ossification GO:0045778 47 20 0,000 0,0505587 0,07381324 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,0505587 0,07376848 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,0505587 0,07372377 ! cAMP metabolic process GO:0046058 36 20 0,000 0,0505587 0,07367912 ! response to vitamin GO:0033273 31 20 0,000 0,0505587 0,07363452 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,0505587 0,07358997 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,0505587 0,07354548 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,0505587 0,07350104 ! response to alkaloid GO:0043279 38 20 0,000 0,0505587 0,07345666 ! retinoid metabolic process GO:0001523 32 20 0,000 0,0505587 0,07341232 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,0505587 0,07336805 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,0505587 0,07332382 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,0505587 0,07327965 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,0505587 0,07323553 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,0505587 0,07319147 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,0505587 0,07314746 ! body fluid secretion GO:0007589 31 20 0,000 0,0505587 0,0731035 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,0505587 0,07305959 ! peptide secretion GO:0002790 35 20 0,000 0,0505587 0,07301574 ! stem cell differentiation GO:0048863 53 20 0,000 0,0505587 0,07297194 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,0505587 0,07292819 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,0505587 0,07288449 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,0505587 0,07284085 ! sensory perception of pain GO:0019233 30 20 0,000 0,0505587 0,07279726 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,0505587 0,07275372 ! diencephalon development GO:0021536 34 20 0,000 0,0505587 0,07271023 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,0505587 0,0726668 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,0505587 0,07262342 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,0505587 0,07258008 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,0505587 0,0725368 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,0505587 0,07249358 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,0505587 0,0724504 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,0505587 0,07240727 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,0505587 0,0723642 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,0505587 0,07232118 ! regulation of glucose import GO:0046324 29 20 0,000 0,0505587 0,07227821 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,0505587 0,07223529 ! actin filament-based movement GO:0030048 43 20 0,000 0,0505587 0,07219242 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,0505587 0,0721496 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,0505587 0,07210683 ! negative regulation of translation GO:0017148 29 20 0,000 0,0505587 0,07206411 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,0505587 0,07202145 ! regulation of cell killing GO:0031341 42 21 0,000 0,05301929 0,0754819 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,05301929 0,07543726 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,05301929 0,07539267 ! hormone secretion GO:0046879 38 21 0,000 0,05301929 0,07534814 ! glycerol metabolic process GO:0006071 34 21 0,000 0,05301929 0,07530366 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,05301929 0,07525924 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,05301929 0,07521486 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,05301929 0,07517054 ! axis specification GO:0009798 38 21 0,000 0,05301929 0,07512627 ! ovarian follicle development GO:0001541 35 21 0,000 0,05301929 0,07508205 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,05301929 0,07503789 ! smooth muscle contraction GO:0006939 46 21 0,000 0,05301929 0,07499377 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,05301929 0,07494971 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,05301929 0,0749057 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,05301929 0,07486174 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,05301929 0,07481783 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,05301929 0,07477398 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,05301929 0,07473017 ! cytolysis GO:0019835 24 21 0,000 0,05301929 0,07468642 ! vasodilation GO:0042311 39 21 0,000 0,05301929 0,07464272 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,05301929 0,07459907 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,05301929 0,07455547 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,05301929 0,07451192 ! oogenesis GO:0048477 36 21 0,000 0,05301929 0,07446842 ! DNA modification GO:0006304 34 21 0,000 0,05301929 0,07442497 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,05301929 0,07438158 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,05301929 0,07433823 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,05301929 0,07429494 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,05301929 0,07425169 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,05301929 0,0742085 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,05301929 0,07416535 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,05301929 0,07412226 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,05301929 0,07407921 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,05301929 0,07403622 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,05301929 0,07399327 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,05301929 0,07395038 ! collagen catabolic process GO:0030574 28 21 0,000 0,05301929 0,07390753 ! sperm-egg recognition GO:0035036 21 21 0,000 0,05301929 0,07386474 ! gut development GO:0048565 39 21 0,000 0,05301929 0,07382199 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,05547358 0,07719459 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,05547358 0,07714997 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,05547358 0,0771054 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,05547358 0,07706088 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,05547358 0,07701641 GO:0034105|positive regulation of tissue remodeling, ! regulation of chemotaxis GO:0050920 40 22 0,000 0,05547358 0,076972 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,05547358 0,07692763 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,05547358 0,07688332 ! regeneration GO:0031099 41 22 0,000 0,05547358 0,07683906 ! keratinization GO:0031424 28 22 0,000 0,05547358 0,07679485 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,05547358 0,07675069 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,05547358 0,07670658 ! sensory perception of taste GO:0050909 28 22 0,000 0,05547358 0,07666252 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,05547358 0,07661851 ! vacuolar transport GO:0007034 36 22 0,000 0,05547358 0,07657455 ! lysosome organization GO:0007040 41 22 0,000 0,05547358 0,07653064 ! central nervous system neuron development GO:0021954 46 22 0,000 0,05547358 0,07648679 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,05547358 0,07644298 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,05547358 0,07639922 ! fucose metabolic process GO:0006004 39 22 0,000 0,05547358 0,07635552 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,05547358 0,07631186 ! ureteric bud development GO:0001657 43 22 0,000 0,05547358 0,07626825 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,05547358 0,0762247 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,05547358 0,07618119 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,05547358 0,07613773 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,05547358 0,07609432 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,05547358 0,07605096 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,05547358 0,07600765 ! sarcomere organization GO:0045214 30 22 0,000 0,05547358 0,07596439 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,05547358 0,07592118 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,05547358 0,07587802 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,05547358 0,07583491 ! protein stabilization GO:0050821 39 22 0,000 0,05547358 0,07579185 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,0579216 0,07909158 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,0579216 0,07904672 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,0579216 0,07900191 ! gluconeogenesis GO:0006094 33 23 0,000 0,0579216 0,07895715 ! viral genome replication GO:0019079 41 23 0,000 0,0579216 0,07891244 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,0579216 0,07886778 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,0579216 0,07882317 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,0579216 0,07877861 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,0579216 0,07873411 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,0579216 0,07868965 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,0579216 0,07864524 ! visual behavior GO:0007632 42 23 0,000 0,0579216 0,07860089 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,0579216 0,07855658 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 0,000 0,0579216 0,07851232 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,0579216 0,07846811 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,0579216 0,07842396 ! peroxisome organization GO:0007031 37 23 0,000 0,0579216 0,07837985 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,0579216 0,07833579 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,0579216 0,07829178 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,0579216 0,07824782 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,0579216 0,07820391 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,0579216 0,07816005 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,0579216 0,07811624 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,0579216 0,07807248 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,0579216 0,07802876 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,0579216 0,0779851 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,0579216 0,07794148 ! fatty acid transport GO:0015908 44 23 0,000 0,0579216 0,07789791 ! platelet activation GO:0030168 37 23 0,000 0,0579216 0,0778544 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,0579216 0,07781093 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,0579216 0,07776751 ! hormone transport GO:0009914 40 23 0,000 0,0579216 0,07772413 ! cell-cell recognition GO:0009988 25 23 0,000 0,0579216 0,07768081 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,0579216 0,07763753 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,0579216 0,0775943 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,0579216 0,07755112 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,0579216 0,07750799 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,0579216 0,07746491 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,06036335 0,08068568 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,06036335 0,08064088 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,06036335 0,08059613 ! spinal cord development GO:0021510 47 24 0,000 0,06036335 0,08055143 ! vacuole organization GO:0007033 43 24 0,000 0,06036335 0,08050678 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,06036335 0,08046218 ! digestive system process GO:0022600 39 24 0,000 0,06036335 0,08041762 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,06036335 0,08037312 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,06036335 0,08032867 ! regulation of behavior GO:0050795 43 24 0,000 0,06036335 0,08028426 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,06036335 0,0802399 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,06036335 0,0801956 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,06036335 0,08015134 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,06036335 0,08010713 ! membrane depolarization GO:0051899 39 24 0,000 0,06036335 0,08006297 ! pallium development GO:0021543 49 24 0,000 0,06036335 0,08001886 ! pentose metabolic process GO:0019321 35 24 0,000 0,06036335 0,07997479 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,06036335 0,07993078 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,06036335 0,07988681 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,06036335 0,0798429 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,06036335 0,07979903 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,06036335 0,0797552 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,06036335 0,07971143 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,06036335 0,07966771 ! regulation of amine transport GO:0051952 40 24 0,000 0,06036335 0,07962403 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,06279886 0,08279126 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,06279886 0,08274592 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,06279886 0,08270063 ! phototransduction GO:0007602 33 25 0,000 0,06279886 0,08265539 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,06279886 0,0826102 GO:0006479|protein amino acid methylation, ! vasculogenesis GO:0001570 46 25 0,000 0,06279886 0,08256506 ! sperm motility GO:0030317 31 25 0,000 0,06279886 0,08251996 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,06279886 0,08247492 ! receptor metabolic process GO:0043112 46 25 0,000 0,06279886 0,08242993 ! chromosome condensation GO:0030261 45 25 0,000 0,06279886 0,08238498 ! osteoblast differentiation GO:0001649 60 25 0,000 0,06279886 0,08234008 ! neural crest cell development GO:0014032 54 25 0,000 0,06279886 0,08229524 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,06279886 0,08225044 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,06279886 0,08220569 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,06279886 0,08216099 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,06279886 0,08211633 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,06279886 0,08207173 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,06279886 0,08202717 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,06279886 0,08198267 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,06279886 0,08193821 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,06279886 0,0818938 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,06279886 0,08184943 ! telomere organization GO:0032200 43 25 0,000 0,06279886 0,08180512 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,06279886 0,08176085 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,06279886 0,08171663 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,06522813 0,08483183 ! embryonic pattern specification GO:0009880 44 26 0,000 0,06522813 0,084786 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,06522813 0,08474022 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,06522813 0,08469449 ! initiation of viral infection GO:0019059 57 26 0,000 0,06522813 0,0846488 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,06522813 0,08460317 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,06522813 0,08455759 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,06522813 0,08451205 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,06522813 0,08446657 ! molting cycle process GO:0022404 50 26 0,000 0,06522813 0,08442113 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,06522813 0,08437574 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,06522813 0,08433041 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,06522813 0,08428511 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,06522813 0,08423987 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,06522813 0,08419468 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,06522813 0,08414954 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,06522813 0,08410444 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,06522813 0,08405939 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,06522813 0,08401439 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,06522813 0,08396944 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,06522813 0,08392454 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,06522813 0,08387968 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,06522813 0,08383487 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,06522813 0,08379011 ! blastocyst development GO:0001824 49 26 0,000 0,06522813 0,0837454 ! leukocyte proliferation GO:0070661 52 26 0,000 0,06522813 0,08370074 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,06522813 0,08365612 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,06522813 0,08361155 ! neuron fate commitment GO:0048663 48 27 0,000 0,06765119 0,08667133 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,06765119 0,0866252 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,06765119 0,08657913 ! iron ion transport GO:0006826 59 27 0,000 0,06765119 0,0865331 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,06765119 0,08648712 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,06765119 0,08644119 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,06765119 0,08639531 ! fat cell differentiation GO:0045444 50 27 0,000 0,06765119 0,08634947 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,06765119 0,08630369 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,06765119 0,08625795 ! autophagy GO:0006914 41 27 0,000 0,06765119 0,08621227 ! male gonad development GO:0008584 44 27 0,000 0,06765119 0,08616663 ! response to toxin GO:0009636 47 27 0,000 0,06765119 0,08612104 ! primary neural tube formation GO:0014020 51 27 0,000 0,06765119 0,08607549 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,06765119 0,08603 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,06765119 0,08598455 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,06765119 0,08593915 ! glutathione metabolic process GO:0006749 39 27 0,000 0,06765119 0,0858938 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,06765119 0,0858485 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,06765119 0,08580325 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,06765119 0,08575804 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,07006804 0,08877499 ! circadian rhythm GO:0007623 50 28 0,000 0,07006804 0,08872827 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,07006804 0,0886816 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,07006804 0,08863497 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,07006804 0,08858839 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,07006804 0,08854187 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,07006804 0,08849539 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,07006804 0,08844896 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,07006804 0,08840258 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,07006804 0,08835624 ! synaptogenesis GO:0007416 42 28 0,000 0,07006804 0,08830996 ! lipid oxidation GO:0034440 43 28 0,000 0,07006804 0,08826373 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,07006804 0,08821754 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,07006804 0,0881714 ! translational initiation GO:0006413 65 29 0,000 0,07247872 0,09115724 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,07247872 0,09110961 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,07247872 0,09106203 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,07247872 0,0910145 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,07247872 0,09096703 ! catechol metabolic process GO:0009712 54 29 0,000 0,07247872 0,0909196 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,07247872 0,09087222 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,07247872 0,09082489 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,07247872 0,09077761 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,07247872 0,09073038 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,07247872 0,0906832 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,07247872 0,09063607 ! cell fate determination GO:0001709 60 29 0,000 0,07247872 0,09058898 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,07247872 0,09054195 ! detection of light stimulus GO:0009583 38 29 0,000 0,07247872 0,09049496 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,07247872 0,09044802 ! tissue homeostasis GO:0001894 48 29 0,000 0,07247872 0,09040114 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,07247872 0,0903543 ! phenol metabolic process GO:0018958 55 30 0,000 0,07488322 0,09330348 ! zinc ion transport GO:0006829 45 30 0,000 0,07488322 0,09325519 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,07488322 0,09320694 ! cell junction assembly GO:0034329 78 30 0,000 0,07488322 0,09315875 ! regulation of innate immune response GO:0045088 51 30 0,000 0,07488322 0,09311061 ! acute-phase response GO:0006953 49 30 0,000 0,07488322 0,09306251 ! myofibril assembly GO:0030239 47 30 0,000 0,07488322 0,09301447 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,07488322 0,09296647 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,07488322 0,09291853 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,07488322 0,09287063 ! phospholipid transport GO:0015914 51 30 0,000 0,07488322 0,09282278 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,07488322 0,09277499 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,07488322 0,09272724 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,07488322 0,09267954 ! eye morphogenesis GO:0048592 60 30 0,000 0,07488322 0,09263189 ! response to heat GO:0009408 50 30 0,000 0,07488322 0,09258429 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,07728157 0,09550049 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,07728157 0,09545146 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,07728157 0,09540249 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,07728157 0,09535356 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,07728157 0,09530469 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,07728157 0,09525587 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,07728157 0,09520709 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,07728157 0,09515837 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,07728157 0,09510969 ! ovulation cycle process GO:0022602 49 31 0,000 0,07728157 0,09506107 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,07728157 0,09501249 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,07728157 0,09496397 ! peptide transport GO:0015833 55 31 0,000 0,07728157 0,09491549 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,07728157 0,09486707 ! iron ion homeostasis GO:0055072 54 31 0,000 0,07728157 0,09481869 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,07728157 0,09477036 ! mesoderm formation GO:0001707 69 31 0,000 0,07728157 0,09472208 ! natural killer cell activation GO:0030101 45 31 0,000 0,07728157 0,09467385 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,07728157 0,09462567 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,07728157 0,09457754 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,07728157 0,09452946 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,07728157 0,09448143 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,07728157 0,09443344 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,07967378 0,09730716 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,07967378 0,09725779 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,07967378 0,09720847 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,07967378 0,0971592 ! cholesterol transport GO:0030301 56 32 0,000 0,07967378 0,09710998 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,07967378 0,09706081 ! spliceosome assembly GO:0000245 67 32 0,000 0,07967378 0,09701169 ! spindle organization GO:0007051 46 32 0,000 0,07967378 0,09696262 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,07967378 0,0969136 ! metanephros development GO:0001656 74 32 0,000 0,07967378 0,09686463 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,07967378 0,09681571 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,07967378 0,09676684 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,07967378 0,09671802 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,07967378 0,09666924 ! muscle cell development GO:0055001 49 32 0,000 0,07967378 0,09662052 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,07967378 0,09657184 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,07967378 0,09652322 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,07967378 0,09647464 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,07967378 0,09642611 ! ovulation cycle GO:0042698 51 32 0,000 0,07967378 0,09637763 ! BMP signaling pathway GO:0030509 64 32 0,000 0,07967378 0,0963292 ! hindbrain development GO:0030902 61 32 0,000 0,07967378 0,09628082 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,07967378 0,09623248 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,07967378 0,0961842 ! gene silencing GO:0016458 65 32 0,000 0,07967378 0,09613596 ! post-embryonic development GO:0009791 69 33 0,000 0,08205986 0,09896543 ! protein targeting to membrane GO:0006612 68 33 0,000 0,08205986 0,09891585 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,08205986 0,09886632 ! ceramide metabolic process GO:0006672 64 33 0,000 0,08205986 0,09881683 ! formation of primary germ layer GO:0001704 72 33 0,000 0,08205986 0,0987674 ! cell fate specification GO:0001708 52 33 0,000 0,08205986 0,09871802 ! sterol transport GO:0015918 57 33 0,000 0,08205986 0,09866868 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,08205986 0,0986194 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,08205986 0,09857016 ! adult locomotory behavior GO:0008344 59 33 0,000 0,08205986 0,09852098 ! negative regulation of protein transport GO:0051224 69 33 0,000 0,08205986 0,09847184 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,08205986 0,09842275 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,08443984 0,10122684 ! glial cell differentiation GO:0010001 63 34 0,000 0,08443984 0,10117643 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,08443984 0,10112607 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,08443984 0,10107575 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,08443984 0,10102549 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,08443984 0,10097528 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,08443984 0,10092512 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,08443984 0,10087501 ! spermatid development GO:0007286 63 34 0,000 0,08443984 0,10082495 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,08443984 0,10077493 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,08443984 0,10072497 ! placenta development GO:0001890 53 34 0,000 0,08443984 0,10067506 ! regulation of muscle development GO:0048634 70 35 0,000 0,08681373 0,10345411 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,08681373 0,10340289 ! negative regulation of secretion GO:0051048 63 35 0,000 0,08681373 0,10335173 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,08681373 0,10330061 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,08681373 0,10324955 ! odontogenesis GO:0042476 66 35 0,000 0,08681373 0,10319854 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,08681373 0,10314758 ! female gonad development GO:0008585 58 35 0,000 0,08681373 0,10309666 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,08681373 0,1030458 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,08681373 0,10299499 ! cytokine production GO:0001816 59 35 0,000 0,08681373 0,10294423 ! neural tube formation GO:0001841 67 35 0,000 0,08681373 0,10289352 ! vesicle localization GO:0051648 64 35 0,000 0,08681373 0,10284286 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,08918155 0,10559587 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,08918155 0,10554392 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,08918155 0,10549203 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,08918155 0,1054402 ! cell junction organization GO:0034330 86 36 0,000 0,08918155 0,10538841 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,08918155 0,10533667 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,08918155 0,10528498 ! positive regulation of cell development GO:0010720 80 36 0,000 0,08918155 0,10523335 ! regulation of proteolysis GO:0030162 72 36 0,000 0,08918155 0,10518176 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,08918155 0,10513023 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,08918155 0,10507875 ! aerobic respiration GO:0009060 55 36 0,000 0,08918155 0,10502731 ! embryonic organ development GO:0048568 57 36 0,000 0,08918155 0,10497593 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,08918155 0,1049246 ! RNA export from nucleus GO:0006405 56 37 0,000 0,0915433 0,10765062 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,0915433 0,10759803 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,0915433 0,10754549 ! sister chromatid segregation GO:0000819 58 37 0,000 0,0915433 0,10749301 ! actomyosin structure organization GO:0031032 62 37 0,000 0,0915433 0,10744057 ! organic anion transport GO:0015711 68 37 0,000 0,0915433 0,10738819 ! tissue remodeling GO:0048771 76 37 0,000 0,0915433 0,10733585 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,0915433 0,10728357 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,0915433 0,10723134 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,0915433 0,10717916 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,0915433 0,10712703 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,0915433 0,10707495 ! glycogen metabolic process GO:0005977 61 37 0,000 0,0915433 0,10702292 ! pigment metabolic process GO:0042440 80 37 0,000 0,0915433 0,10697094 ! spermatid differentiation GO:0048515 66 37 0,000 0,0915433 0,10691902 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,093899 0,10961718 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,093899 0,10956402 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,093899 0,10951091 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,093899 0,10945785 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,093899 0,10940484 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,093899 0,10935189 ! lipid homeostasis GO:0055088 67 38 0,000 0,093899 0,10929898 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,093899 0,10924613 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,093899 0,10919333 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,093899 0,10914058 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,093899 0,10908788 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,093899 0,10903523 ! glucan metabolic process GO:0044042 62 38 0,000 0,093899 0,10898263 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,09624868 0,11165589 ! learning GO:0007612 77 39 0,000 0,09624868 0,11160208 ! ear morphogenesis GO:0042471 60 39 0,000 0,09624868 0,11154832 ! organic ether metabolic process GO:0018904 55 39 0,000 0,09624868 0,11149462 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,09624868 0,11144096 ! ion transmembrane transport GO:0034220 66 39 0,000 0,09624868 0,11138736 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,09624868 0,11133381 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,09624868 0,11128031 ! RNA modification GO:0009451 57 39 0,000 0,09624868 0,11122686 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,09624868 0,11117346 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,09859234 0,11382589 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,09859234 0,1137713 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,09859234 0,11371676 ! feeding behavior GO:0007631 59 40 0,000 0,09859234 0,11366227 ! negative regulation of binding GO:0051100 72 40 0,000 0,09859234 0,11360784 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,09859234 0,11355345 ! mesenchymal cell development GO:0014031 87 40 0,000 0,09859234 0,11349912 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,09859234 0,11344484 ! maintenance of protein location GO:0045185 91 40 0,000 0,09859234 0,11339061 ! cytokinesis GO:0000910 72 40 0,000 0,09859234 0,11333644 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,10093 0,11596828 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,10093 0,11591292 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,10093 0,11585762 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,10093 0,11580237 ! gliogenesis GO:0042063 88 41 0,000 0,10093 0,11574718 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,10093 0,11569203 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,10093 0,11563694 ! female gamete generation GO:0007292 61 41 0,000 0,10093 0,1155819 ! polyol metabolic process GO:0019751 66 41 0,000 0,10093 0,11552691 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,10093 0,11547198 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,10326167 0,11808345 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,10326167 0,11802736 ! regulation of tube size GO:0035150 71 42 0,000 0,10326167 0,11797131 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,10326167 0,11791532 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,10326167 0,11785939 ! regulation of intracellular protein transport GO:0033157 80 42 0,000 0,10326167 0,1178035 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,10326167 0,11774767 ! neuron migration GO:0001764 79 42 0,000 0,10326167 0,11769189 ! regulation of protein secretion GO:0050708 71 42 0,000 0,10326167 0,11763617 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,10326167 0,11758049 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,10558738 0,12017182 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,10558738 0,120115 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,10558738 0,12005824 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,10558738 0,12000153 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,10558738 0,11994487 ! glucose transport GO:0015758 65 43 0,000 0,10558738 0,11988826 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,10558738 0,11983171 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,10558738 0,11977522 ! neural tube development GO:0021915 77 43 0,000 0,10558738 0,11971877 ! striated muscle contraction GO:0006941 77 43 0,000 0,10558738 0,11966238 ! phagocytosis GO:0006909 90 43 0,000 0,10558738 0,11960604 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,10558738 0,11954976 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,10790713 0,12211879 ! hexose transport GO:0008645 67 44 0,000 0,10790713 0,12206138 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,10790713 0,12200402 ! male sex differentiation GO:0046661 76 44 0,000 0,10790713 0,12194671 ! biopolymer methylation GO:0043414 84 44 0,000 0,10790713 0,12188946 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,10790713 0,12183226 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,10790713 0,12177512 ! developmental growth GO:0048589 82 44 0,000 0,10790713 0,12171803 ! maintenance of location in cell GO:0051651 97 44 0,000 0,10790713 0,12166099 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,11022094 0,12421151 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,11022094 0,12415336 ! leukocyte migration GO:0050900 68 45 0,000 0,11022094 0,12409527 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,11022094 0,12403722 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,11022094 0,12397923 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,11022094 0,1239213 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,11022094 0,12386342 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,11022094 0,12380559 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,11022094 0,12374782 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,11022094 0,1236901 ! cell growth GO:0016049 84 45 0,000 0,11022094 0,12363244 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,11252883 0,12616233 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 0,000 0,11252883 0,12610357 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,11252883 0,12604486 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,11252883 0,12598621 ! pigmentation GO:0043473 100 46 0,000 0,11252883 0,12592761 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,11252883 0,12586906 ! positive regulation of defense response GO:0031349 76 47 0,000 0,1148308 0,12838425 ! response to calcium ion GO:0051592 81 47 0,000 0,1148308 0,12832462 ! endosome transport GO:0016197 108 47 0,000 0,1148308 0,12826505 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,1148308 0,12820553 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,1148308 0,12814606 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,1148308 0,12808665 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,1148308 0,1280273 ! methylation GO:0032259 90 47 0,000 0,1148308 0,127968 ! protein homooligomerization GO:0051260 76 47 0,000 0,1148308 0,12790876 ! Notch signaling pathway GO:0007219 96 48 0,000 0,11712689 0,13040596 ! cellular component disassembly GO:0022411 86 48 0,000 0,11712689 0,13034565 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,11712689 0,13028539 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,11712689 0,13022518 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,11712689 0,13016503 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,11712689 0,13010493 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,11712689 0,1300449 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,11941709 0,13252653 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,11941709 0,13246543 ! regulation of ion transport GO:0043269 77 49 0,000 0,11941709 0,13240438 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,11941709 0,1323434 ! peptide metabolic process GO:0006518 76 49 0,000 0,11941709 0,13228247 ! response to temperature stimulus GO:0009266 76 49 0,000 0,11941709 0,13222159 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,11941709 0,13216077 ! endocrine system development GO:0035270 104 49 0,000 0,11941709 0,13210001 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,11941709 0,1320393 ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,11941709 0,13197865 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,11941709 0,13191805 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,12170143 0,13437982 ! neuromuscular process GO:0050905 99 50 0,000 0,12170143 0,13431818 ! regulation of ossification GO:0030278 117 50 0,000 0,12170143 0,13425659 ! inner ear development GO:0048839 79 50 0,000 0,12170143 0,13419507 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,12170143 0,13413359 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,12170143 0,13407218 ! viral infectious cycle GO:0019058 99 51 0,000 0,12397991 0,13651976 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,12397991 0,13645731 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,12397991 0,13639491 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,12397991 0,13633257 ! excretion GO:0007588 83 51 0,000 0,12397991 0,13627029 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,12397991 0,13620807 ! chromatin remodeling GO:0006338 109 51 0,000 0,12397991 0,1361459 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,12397991 0,13608379 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,12397991 0,13602174 ! vesicle organization GO:0016050 107 51 0,000 0,12397991 0,13595974 ! regulation of cell shape GO:0008360 125 51 0,000 0,12397991 0,1358978 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,12397991 0,13583592 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,12625257 0,13826294 ! membrane fusion GO:0006944 110 52 0,000 0,12625257 0,13820003 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,12625257 0,13813719 ! amino acid activation GO:0043038 92 52 0,000 0,12625257 0,1380744 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,12625257 0,13801167 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,1285194 0,14042583 ! RNA catabolic process GO:0006401 93 53 0,000 0,1285194 0,14036208 ! regulation of translational initiation GO:0006446 82 53 0,000 0,1285194 0,1402984 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,1285194 0,14023477 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,1285194 0,1401712 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,1285194 0,14010769 ! cell maturation GO:0048469 100 53 0,000 0,1285194 0,14004424 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,1285194 0,13998084 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,13078042 0,14237905 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,13078042 0,14231465 ! cell recognition GO:0008037 85 54 0,000 0,13078042 0,14225032 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,13078042 0,14218604 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,13078042 0,14212182 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,13078042 0,14205765 ! chloride transport GO:0006821 90 55 0,000 0,13303566 0,14444215 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,13303566 0,14437699 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,13303566 0,1443119 ! regulation of protein catabolic process GO:0042176 116 55 0,000 0,13303566 0,14424687 ! gastrulation GO:0007369 112 55 0,000 0,13303566 0,14418189 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,13303566 0,14411697 ! RNA elongation GO:0006354 79 55 0,000 0,13303566 0,14405211 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,13303566 0,14398731 ! regulation of actin filament length GO:0030832 105 56 0,000 0,13528512 0,14635611 ! sensory perception of smell GO:0007608 80 56 0,000 0,13528512 0,14629033 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,13528512 0,14622462 ! proton transport GO:0015992 94 56 0,000 0,13528512 0,14615896 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,13528512 0,14609335 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,13752881 0,14844968 ! lipid modification GO:0030258 97 57 0,000 0,13752881 0,14838311 ! regulation of intracellular transport GO:0032386 101 57 0,000 0,13752881 0,1483166 ! maintenance of location GO:0051235 118 57 0,000 0,13752881 0,14825015 ! hydrogen transport GO:0006818 97 58 0,000 0,13976676 0,15059509 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,13976676 0,15052768 ! regulation of endocytosis GO:0030100 91 58 0,000 0,13976676 0,15046033 ! adult behavior GO:0030534 99 58 0,000 0,13976676 0,15039304 ! positive regulation of secretion GO:0051047 95 59 0,000 0,14199898 0,15272666 ! regulation of cellular component size GO:0032535 109 59 0,000 0,14199898 0,15265842 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,14199898 0,15259024 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,14199898 0,15252212 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,14199898 0,15245406 ! DNA catabolic process GO:0006308 86 59 0,000 0,14199898 0,15238606 ! establishment of organelle localization GO:0051656 109 59 0,000 0,14199898 0,15231812 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,14422548 0,15463748 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,14422548 0,1545686 ! regulation of heart contraction GO:0008016 110 60 0,000 0,14422548 0,15449978 ! camera-type eye development GO:0043010 116 60 0,000 0,14422548 0,15443102 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,14422548 0,15436232 ! kidney development GO:0001822 122 60 0,000 0,14422548 0,15429369 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,14644627 0,15659988 ! mesoderm development GO:0007498 119 61 0,000 0,14644627 0,15653031 ! tRNA processing GO:0008033 89 61 0,000 0,14644627 0,1564608 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,14644627 0,15639136 ! ear development GO:0043583 103 62 0,000 0,14866138 0,15868646 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,14866138 0,15861609 ! gonad development GO:0008406 98 62 0,000 0,14866138 0,15854578 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,14866138 0,15847553 ! regulation of mitosis GO:0007088 105 63 0,000 0,15087081 0,16075959 GO:0051783|regulation of nuclear division, ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,15087081 0,16068843 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,15087081 0,16061733 ! detection of external stimulus GO:0009581 91 63 0,000 0,15087081 0,16054629 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,15087081 0,16047531 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,15307458 0,16274743 ! cell redox homeostasis GO:0045454 102 64 0,000 0,15307458 0,16267554 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,15307458 0,16260372 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,15307458 0,16253196 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,1552727 0,16479317 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,1552727 0,16472051 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,1552727 0,16464791 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,1552727 0,16457538 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,1552727 0,16450291 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,15746519 0,16675231 ! actin filament organization GO:0007015 148 66 0,000 0,15746519 0,16667895 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,15746519 0,16660565 ! extracellular matrix organization GO:0030198 133 66 0,000 0,15746519 0,16653242 ! secondary metabolic process GO:0019748 116 66 0,000 0,15746519 0,16645925 ! developmental maturation GO:0021700 116 66 0,000 0,15746519 0,16638614 ! cell projection assembly GO:0030031 120 66 0,000 0,15746519 0,1663131 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,15965206 0,16854886 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,15965206 0,16847494 ! chromosome segregation GO:0007059 113 67 0,000 0,15965206 0,16840108 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,15965206 0,16832728 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,15965206 0,16825355 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,15965206 0,16817989 ! activation of immune response GO:0002253 105 67 0,000 0,15965206 0,16810629 ! amino acid transport GO:0006865 125 68 0,000 0,16183333 0,17032852 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,16183333 0,17025404 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,16183333 0,17017963 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,16183333 0,17010528 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,16183333 0,170031 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,16400901 0,17224168 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,16400901 0,17216653 ! urogenital system development GO:0001655 137 69 0,000 0,16400901 0,17209144 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,16400901 0,17201643 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,16400901 0,17194147 ! antigen processing and presentation GO:0019882 104 69 0,000 0,16400901 0,17186659 ! appendage morphogenesis GO:0035107 135 70 0,000 0,16617912 0,17406485 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,16834366 0,17625537 ! reproductive structure development GO:0048608 113 71 0,000 0,16834366 0,1761787 ! appendage development GO:0048736 136 71 0,000 0,16834366 0,17610211 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,16834366 0,17602557 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,16834366 0,17594911 ! regulation of immune effector process GO:0002697 137 71 0,000 0,16834366 0,17587271 ! acute inflammatory response GO:0002526 113 72 0,000 0,17050265 0,17805095 ! phosphoinositide metabolic process GO:0030384 128 72 0,000 0,17050265 0,1779737 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,17050265 0,17789653 ! carbohydrate transport GO:0008643 110 72 0,000 0,17050265 0,17781941 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,17050265 0,17774237 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,17050265 0,17766539 ! learning or memory GO:0007611 147 73 0,000 0,17265612 0,17983144 ! regulation of blood pressure GO:0008217 125 73 0,000 0,17265612 0,17975362 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,17265612 0,17967587 ! fertilization GO:0009566 90 73 0,000 0,17265612 0,17959819 ! transition metal ion transport GO:0000041 126 74 0,000 0,17480406 0,18175392 ! neurotransmitter transport GO:0006836 123 74 0,000 0,17480406 0,18167541 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,17480406 0,18159697 ! eye development GO:0001654 143 74 0,000 0,17480406 0,18151859 ! organelle localization GO:0051640 136 74 0,000 0,17480406 0,18144028 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,1769465 0,18358486 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,1769465 0,18350572 ! rhythmic process GO:0048511 128 75 0,000 0,1769465 0,18342666 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,17908345 0,18556192 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,17908345 0,18548204 ! defense response to bacterium GO:0042742 89 76 0,000 0,17908345 0,18540223 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,17908345 0,18532248 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,18121492 0,18744759 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,18121492 0,18736704 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,18121492 0,18728655 ! blood coagulation GO:0007596 146 78 0,000 0,18334092 0,18940243 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,18334092 0,18932114 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,18334092 0,18923992 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,18334092 0,18915877 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,18546148 0,1912646 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,18546148 0,19118266 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,18546148 0,19110078 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,18546148 0,19101897 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,18546148 0,19093724 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,1875766 0,19303221 ! response to metal ion GO:0010038 140 80 0,000 0,1875766 0,19294968 ! muscle cell differentiation GO:0042692 159 80 0,000 0,1875766 0,19286722 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,1875766 0,19278484 ! inorganic anion transport GO:0015698 138 80 0,000 0,1875766 0,19270252 ! digestion GO:0007586 112 81 0,000 0,1896863 0,1947867 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,1896863 0,1947036 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,1896863 0,19462057 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,19179059 0,19669572 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,19179059 0,19661191 ! response to nutrient GO:0007584 125 82 0,000 0,19179059 0,19652818 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,19179059 0,19644451 ! regulation of lyase activity GO:0051339 160 83 0,000 0,19388949 0,19850983 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,195983 0,20056789 ! hemostasis GO:0007599 158 84 0,000 0,195983 0,20048261 ! negative regulation of transport GO:0051051 153 84 0,000 0,195983 0,20039741 ! regulation of ligase activity GO:0051340 142 84 0,000 0,195983 0,20031228 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,195983 0,20022722 ! response to unfolded protein GO:0006986 131 85 0,000 0,19807115 0,2022747 ! nucleosome assembly GO:0006334 122 85 0,000 0,19807115 0,20218888 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,19807115 0,20210313 ! amine biosynthetic process GO:0009309 138 86 0,000 0,20015394 0,20414175 ! response to inorganic substance GO:0010035 153 86 0,000 0,20015394 0,20405525 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,20015394 0,20396882 ! chromatin assembly GO:0031497 124 86 0,000 0,20015394 0,20388247 ! tube morphogenesis GO:0035239 176 86 0,000 0,20015394 0,20379618 ! amine transport GO:0015837 155 86 0,000 0,20015394 0,20370998 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,2022314 0,20573731 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,2022314 0,20565035 ! regulation of protein transport GO:0051223 154 87 0,000 0,2022314 0,20556347 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 0,000 0,20430352 0,20758204 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,20430352 0,20749442 ! regulation of neurological system process GO:0031644 148 88 0,000 0,20430352 0,20740687 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,20430352 0,20731939 ! cellular defense response GO:0006968 114 89 0,000 0,20637033 0,20932843 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,20637033 0,20924021 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,20843185 0,21124138 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,20843185 0,21115243 ! sex differentiation GO:0007548 145 90 0,000 0,20843185 0,21106356 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,20843185 0,21097477 ! sterol metabolic process GO:0016125 152 91 0,000 0,21048807 0,21296649 ! response to protein stimulus GO:0051789 149 91 0,000 0,21048807 0,21287697 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,21048807 0,21278752 ! regulation of defense response GO:0031347 149 92 0,000 0,21253903 0,21477064 ! nucleosome organization GO:0034728 138 92 0,000 0,21253903 0,21468048 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,21253903 0,21459039 ! vitamin metabolic process GO:0006766 139 92 0,000 0,21253903 0,21450038 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,21458472 0,21647415 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,21458472 0,21638342 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,21458472 0,21629277 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,21458472 0,21620219 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,21662517 0,21816666 ! female pregnancy GO:0007565 164 94 0,000 0,21662517 0,21807538 ! transcription initiation GO:0006352 153 94 0,000 0,21662517 0,21798417 ! forebrain development GO:0030900 188 95 0,000 0,21866038 0,21994017 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,21866038 0,21984826 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,22069038 0,22179659 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,22069038 0,22170399 ! positive regulation of immune response GO:0050778 156 96 0,000 0,22069038 0,22161146 ! detection of stimulus GO:0051606 151 96 0,000 0,22069038 0,221519 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,22271516 0,22345817 ! protein ubiquitination GO:0016567 217 97 0,000 0,22271516 0,22336502 ! hormone metabolic process GO:0042445 157 97 0,000 0,22271516 0,22327195 ! regulation of protein localization GO:0032880 176 97 0,000 0,22271516 0,22317896 ! response to virus GO:0009615 160 98 0,000 0,22473476 0,22510901 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,22473476 0,22501533 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,22473476 0,22492173 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,22674917 0,22684346 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,22674917 0,22674917