pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6447-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of phosphorylation GO:0042326 41 23 6,000 2,372E-10 5,456E-07 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 6,000 4,594E-10 5,284E-07 GO:0045936|negative regulation of phosphate metabolic process, ! cell cycle arrest GO:0007050 150 86 7,000 2,456E-07 1,883E-04 ! regulation of epithelial cell proliferation GO:0050678 71 39 5,000 4,017E-07 2,31E-04 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 5,000 7,326E-07 3,37E-04 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 4,000 7,987E-07 3,062E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 5,000 2,061E-06 6,773E-04 ! interphase of mitotic cell cycle GO:0051329 156 86 6,000 3,526E-06 1,014E-03 ! negative regulation of protein kinase activity GO:0006469 99 57 5,000 4,005E-06 1,023E-03 ! interphase GO:0051325 159 88 6,000 4,115E-06 9,465E-04 ! negative regulation of kinase activity GO:0033673 100 58 5,000 4,44E-06 9,283E-04 ! negative regulation of transferase activity GO:0051348 105 61 5,000 5,981E-06 1,146E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 5,000 7,23E-06 1,279E-03 ! positive regulation of protein ubiquitination GO:0031398 8 6 2,000 7,906E-06 1,299E-03 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 3,000 1,038E-05 1,591E-03 ! induction of apoptosis by intracellular signals GO:0008629 67 40 4,000 1,124E-05 1,616E-03 ! positive regulation of phosphorylation GO:0042327 102 70 5,000 1,337E-05 1,809E-03 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 2,000 1,376E-05 1,758E-03 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 5,000 1,574E-05 1,906E-03 GO:0045937|positive regulation of phosphate metabolic process, ! cellular response to extracellular stimulus GO:0031668 32 21 3,000 1,584E-05 1,822E-03 ! vasculogenesis GO:0001570 33 22 3,000 1,925E-05 2,108E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 2,000 2,19E-05 2,289E-03 ! induction of positive chemotaxis GO:0050930 14 8 2,000 2,19E-05 2,19E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 2,000 2,19E-05 2,098E-03 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 2,000 2,19E-05 2,014E-03 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 2,19E-05 1,937E-03 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 2,000 3,267E-05 2,783E-03 ! regulation of B cell proliferation GO:0030888 15 10 2,000 4,641E-05 3,812E-03 ! regulation of positive chemotaxis GO:0050926 17 11 2,000 6,347E-05 5,034E-03 GO:0050927|positive regulation of positive chemotaxis, ! chondrocyte differentiation GO:0002062 17 11 2,000 6,347E-05 4,866E-03 ! negative regulation of glucose import GO:0046325 14 11 2,000 6,347E-05 4,709E-03 GO:0010829|negative regulation of glucose transport, ! negative regulation of mast cell proliferation GO:0070667 17 11 2,000 6,347E-05 4,562E-03 GO:0042130|negative regulation of T cell proliferation, ! negative regulation of cell growth GO:0030308 106 62 4,000 9,699E-05 6,76E-03 ! androgen receptor signaling pathway GO:0030521 54 33 3,000 1,011E-04 6,837E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 2,000 1,088E-04 7,151E-03 ! negative regulation of cell size GO:0045792 108 64 4,000 1,129E-04 7,215E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 4,000 1,129E-04 7,02E-03 ! phosphoinositide phosphorylation GO:0046854 21 14 2,000 1,377E-04 8,337E-03 ! axon cargo transport GO:0008088 27 14 2,000 1,377E-04 8,124E-03 ! regulation of protein ubiquitination GO:0031396 19 15 2,000 1,712E-04 9,847E-03 ! lipid phosphorylation GO:0046834 23 15 2,000 1,712E-04 9,607E-03 ! regulation of the force of heart contraction GO:0002026 21 15 2,000 1,712E-04 9,378E-03 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 2,000 1,712E-04 9,16E-03 ! negative regulation of leukocyte proliferation GO:0070664 25 15 2,000 1,712E-04 8,952E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! cell growth GO:0016049 61 39 3,000 1,963E-04 0,01003152 ! neutrophil chemotaxis GO:0030593 21 16 2,000 2,096E-04 0,01048121 ! inner ear receptor cell differentiation GO:0060113 30 16 2,000 2,096E-04 0,01025821 ! negative regulation of growth GO:0045926 123 75 4,000 2,395E-04 0,01147601 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 2,000 2,532E-04 0,01188313 ! inactivation of MAPK activity GO:0000188 27 17 2,000 2,532E-04 0,01164547 ! positive regulation of protein modification process GO:0031401 107 78 4,000 2,878E-04 0,0129787 ! mechanoreceptor differentiation GO:0042490 32 18 2,000 3,021E-04 0,01336419 ! apoptotic mitochondrial changes GO:0008637 29 18 2,000 3,021E-04 0,01311203 ! cellular response to nutrient levels GO:0031669 27 18 2,000 3,021E-04 0,01286922 ! regulation of glucose import GO:0046324 21 18 2,000 3,021E-04 0,01263523 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 25 18 2,000 3,021E-04 0,0124096 ! regulation of mast cell proliferation GO:0070666 64 44 3,000 3,148E-04 0,01270107 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 3,569E-04 0,01415109 ! cell structure disassembly during apoptosis GO:0006921 24 19 2,000 3,569E-04 0,01391124 ! apoptotic nuclear changes GO:0030262 24 19 2,000 3,569E-04 0,01367939 ! positive regulation of intracellular transport GO:0032388 29 19 2,000 3,569E-04 0,01345514 ! regulation of leukocyte proliferation GO:0070663 71 47 3,000 4,065E-04 0,01508053 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! microtubule-based transport GO:0010970 37 20 2,000 4,176E-04 0,01524396 ! positive regulation of locomotion GO:0040017 35 20 2,000 4,176E-04 0,01500577 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 30 20 2,000 4,176E-04 0,01477491 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 2,000 4,845E-04 0,01688422 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 2,000 4,845E-04 0,01663222 ! regulation of chemotaxis GO:0050920 36 21 2,000 4,845E-04 0,01638763 ! ear development GO:0043583 72 50 3,000 5,159E-04 0,01719787 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 5,408E-04 0,01776778 ! microvillus organization GO:0032528 7 5 1,000 5,408E-04 0,01751753 GO:0030033|microvillus assembly, ! peptidyl-histidine phosphorylation GO:0018106 7 5 1,000 5,408E-04 0,01727423 ! early endosome to late endosome transport GO:0045022 11 5 1,000 5,408E-04 0,0170376 ! regulation of behavior GO:0050795 38 22 2,000 5,58E-04 0,01734216 ! male meiosis GO:0007140 7 6 1,000 8,072E-04 0,02475367 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 1,000 8,072E-04 0,02442796 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 8,072E-04 0,02411071 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 8,072E-04 0,0238016 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 1,000 8,072E-04 0,02350032 ! anterograde axon cargo transport GO:0008089 8 6 1,000 8,072E-04 0,02320656 ! enucleate erythrocyte differentiation GO:0043353 9 6 1,000 8,072E-04 0,02292006 ! ER overload response GO:0006983 7 6 1,000 8,072E-04 0,02264055 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 1,000 8,072E-04 0,02236777 ! coenzyme A metabolic process GO:0015936 9 6 1,000 8,072E-04 0,02210149 ! peptidyl-histidine modification GO:0018202 9 6 1,000 8,072E-04 0,02184147 ! midbrain development GO:0030901 6 6 1,000 8,072E-04 0,0215875 ! negative regulation of B cell activation GO:0050869 9 6 1,000 8,072E-04 0,02133937 ! regulation of chromosome organization GO:0033044 35 25 2,000 8,199E-04 0,02142823 ! negative regulation of lymphocyte activation GO:0051250 37 25 2,000 8,199E-04 0,02118746 ! steroid hormone receptor signaling pathway GO:0030518 96 58 3,000 9,079E-04 0,0232026 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 2,000 9,218E-04 0,02329791 ! negative regulation of protein modification process GO:0031400 50 26 2,000 9,218E-04 0,02304467 ! negative regulation of leukocyte activation GO:0002695 39 27 2,000 1,031E-03 0,02550778 ! negative regulation of transcription regulator activity GO:0090048 47 27 2,000 1,031E-03 0,02523642 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 1,125E-03 0,02722606 ! regulation of lipid kinase activity GO:0043550 12 7 1,000 1,125E-03 0,02694245 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 1,000 1,125E-03 0,0266647 ! synaptic vesicle endocytosis GO:0048488 16 7 1,000 1,125E-03 0,02639261 ! ATP catabolic process GO:0006200 10 7 1,000 1,125E-03 0,02612602 ! negative regulation of MAP kinase activity GO:0043407 54 28 2,000 1,149E-03 0,02642525 ! regulation of B cell activation GO:0050864 42 28 2,000 1,149E-03 0,02616361 ! regulation of transcription factor activity GO:0051090 97 63 3,000 1,239E-03 0,02793334 GO:0090046|regulation of transcription regulator activity, ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 3,000 1,239E-03 0,02766215 ! cell cycle checkpoint GO:0000075 108 64 3,000 1,314E-03 0,02905607 ! negative regulation of cell activation GO:0050866 44 30 2,000 1,409E-03 0,03085356 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 1,492E-03 0,03237591 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 1,000 1,492E-03 0,03207333 ! middle ear morphogenesis GO:0042474 9 8 1,000 1,492E-03 0,03177636 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 1,000 1,492E-03 0,03148483 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 1,492E-03 0,03119861 ! regulation of Notch signaling pathway GO:0008593 18 8 1,000 1,492E-03 0,03091754 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 1,000 1,492E-03 0,03064149 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 1,000 1,492E-03 0,03037033 ! induction of an organ GO:0001759 11 8 1,000 1,492E-03 0,03010392 ! regulation of macrophage differentiation GO:0045649 14 8 1,000 1,492E-03 0,02984215 ! regulation of telomere maintenance GO:0032204 10 8 1,000 1,492E-03 0,02958489 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 2,000 1,551E-03 0,0304902 ! leukocyte chemotaxis GO:0030595 43 31 2,000 1,551E-03 0,03023181 GO:0060326|cell chemotaxis, ! regulation of protein stability GO:0031647 48 32 2,000 1,702E-03 0,03290029 ! nucleus organization GO:0006997 49 33 2,000 1,862E-03 0,03569502 ! negative regulation of DNA binding GO:0043392 54 33 2,000 1,862E-03 0,03540002 ! receptor clustering GO:0043113 15 9 1,000 1,909E-03 0,03599105 ! motor axon guidance GO:0008045 14 9 1,000 1,909E-03 0,03569844 ! alpha-beta T cell differentiation GO:0046632 14 9 1,000 1,909E-03 0,03541055 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 1,000 1,909E-03 0,03512727 ! localization within membrane GO:0051668 15 9 1,000 1,909E-03 0,03484848 ! negative regulation of transport GO:0051051 116 73 3,000 2,138E-03 0,03871926 ! Notch signaling pathway GO:0007219 56 35 2,000 2,21E-03 0,03971142 ! regulation of intracellular protein transport GO:0033157 59 35 2,000 2,21E-03 0,03940358 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 1,000 2,375E-03 0,04201499 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 2,375E-03 0,04169426 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 1,000 2,375E-03 0,0413784 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 2,375E-03 0,04106728 ! alpha-beta T cell activation GO:0046631 16 10 1,000 2,375E-03 0,04076081 ! purine ribonucleotide catabolic process GO:0009154 14 10 1,000 2,375E-03 0,04045888 ! developmental induction GO:0031128 13 10 1,000 2,375E-03 0,04016139 GO:0045168|cell-cell signaling involved in cell fate specification, ! cytoplasmic sequestering of protein GO:0051220 14 10 1,000 2,375E-03 0,03986824 ! negative regulation of binding GO:0051100 58 36 2,000 2,398E-03 0,03996564 ! regulation of DNA binding GO:0051101 119 77 3,000 2,598E-03 0,04299328 ! regulation of T cell proliferation GO:0042129 58 38 2,000 2,803E-03 0,04604497 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 2,888E-03 0,04711542 ! detection of mechanical stimulus GO:0050982 15 11 1,000 2,888E-03 0,04678363 ! dopamine receptor signaling pathway GO:0007212 22 11 1,000 2,888E-03 0,04645647 ! oligodendrocyte differentiation GO:0048709 14 11 1,000 2,888E-03 0,04613385 ! ribonucleotide catabolic process GO:0009261 16 11 1,000 2,888E-03 0,04581569 ! actin cytoskeleton reorganization GO:0031532 21 11 1,000 2,888E-03 0,04550188 ! nucleoside triphosphate catabolic process GO:0009143 15 11 1,000 2,888E-03 0,04519235 ! positive regulation of response to external stimulus GO:0032103 65 40 2,000 3,247E-03 0,0504636 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 2,000 3,247E-03 0,05012492 ! inner ear development GO:0048839 57 40 2,000 3,247E-03 0,04979075 ! ATP synthesis coupled electron transport GO:0042773 48 40 2,000 3,247E-03 0,04946101 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 2,000 3,247E-03 0,04913561 ! JAK-STAT cascade GO:0007259 53 40 2,000 3,247E-03 0,04881446 ! positive regulation of protein transport GO:0051222 55 40 2,000 3,247E-03 0,04849749 ! regulation of interleukin-12 production GO:0032655 16 12 1,000 3,449E-03 0,05118202 ! histone acetylation GO:0016573 23 12 1,000 3,449E-03 0,05085393 ! histone methylation GO:0016571 15 12 1,000 3,449E-03 0,05053002 ! peptidyl-lysine modification GO:0018205 18 12 1,000 3,449E-03 0,05021021 ! regulation of T cell differentiation GO:0045580 59 41 2,000 3,485E-03 0,05040794 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 2,000 3,733E-03 0,05365589 ! cellular component disassembly GO:0022411 64 42 2,000 3,733E-03 0,05332263 ! leukocyte migration GO:0050900 60 43 2,000 3,991E-03 0,05666153 ! activation of caspase activity GO:0006919 65 43 2,000 3,991E-03 0,05631392 ! Wnt receptor signaling pathway GO:0016055 130 87 3,000 4,037E-03 0,05662092 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 4,057E-03 0,05654611 ! intermediate filament cytoskeleton organization GO:0045104 23 13 1,000 4,057E-03 0,05620548 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 4,057E-03 0,05586892 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 4,057E-03 0,05553636 ! neuromuscular synaptic transmission GO:0007274 20 13 1,000 4,057E-03 0,05520774 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 1,000 4,057E-03 0,05488299 ! induction of apoptosis by extracellular signals GO:0008624 74 44 2,000 4,26E-03 0,05729732 ! regulation of inflammatory response GO:0050727 60 44 2,000 4,26E-03 0,0569642 ! positive regulation of cell cycle GO:0045787 77 45 2,000 4,54E-03 0,06035408 ! positive regulation of defense response GO:0031349 59 45 2,000 4,54E-03 0,06000722 ! protein amino acid autophosphorylation GO:0046777 80 45 2,000 4,54E-03 0,05966432 ! cellular response to starvation GO:0009267 21 14 1,000 4,71E-03 0,06154729 ! G1/S transition checkpoint GO:0031575 33 14 1,000 4,71E-03 0,06119957 ! intermediate filament-based process GO:0045103 24 14 1,000 4,71E-03 0,06085575 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 4,71E-03 0,06051578 ! epithelial to mesenchymal transition GO:0001837 22 14 1,000 4,71E-03 0,06017958 ! histone modification GO:0016570 68 46 2,000 4,83E-03 0,06137952 ! response to UV GO:0009411 75 46 2,000 4,83E-03 0,06104227 ! peptidyl-amino acid modification GO:0018193 147 93 3,000 5,118E-03 0,06432911 ! respiratory electron transport chain GO:0022904 59 47 2,000 5,132E-03 0,06414903 ! covalent chromatin modification GO:0016569 75 47 2,000 5,132E-03 0,06380228 ! negative regulation of immune system process GO:0002683 73 47 2,000 5,132E-03 0,06345926 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 5,408E-03 0,06651465 ! regulation of survival gene product expression GO:0045884 20 15 1,000 5,408E-03 0,06616085 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 5,408E-03 0,06581079 ! positive regulation of caspase activity GO:0043280 72 48 2,000 5,445E-03 0,06590898 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 2,000 5,445E-03 0,06556391 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 2,000 5,445E-03 0,06522243 ! regulation of lymphocyte differentiation GO:0045619 69 48 2,000 5,445E-03 0,06488449 ! regulation of binding GO:0051098 151 95 3,000 5,518E-03 0,06541771 ! regulation of intracellular transport GO:0032386 78 49 2,000 5,769E-03 0,06803998 ! integrin-mediated signaling pathway GO:0007229 81 49 2,000 5,769E-03 0,06769284 ! cartilage development GO:0051216 70 49 2,000 5,769E-03 0,06734922 ! lipid modification GO:0030258 73 50 2,000 6,104E-03 0,0709037 ! protein amino acid acetylation GO:0006473 28 16 1,000 6,151E-03 0,0710867 ! G1 phase GO:0051318 27 16 1,000 6,151E-03 0,07073127 ! signal complex assembly GO:0007172 29 17 1,000 6,937E-03 0,07937704 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 1,000 6,937E-03 0,07898408 ! neuromuscular junction development GO:0007528 23 17 1,000 6,937E-03 0,078595 ! negative regulation of protein catabolic process GO:0042177 26 17 1,000 6,937E-03 0,07820973 ! peptidyl-serine modification GO:0018209 27 17 1,000 6,937E-03 0,07782822 ! DNA catabolic process GO:0006308 67 54 2,000 7,56E-03 0,08440989 ! positive regulation of DNA replication GO:0045740 29 18 1,000 7,766E-03 0,08629114 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 1,000 7,766E-03 0,08587628 ! somitogenesis GO:0001756 24 18 1,000 7,766E-03 0,08546539 ! synaptic vesicle transport GO:0048489 33 18 1,000 7,766E-03 0,08505841 ! purine nucleotide catabolic process GO:0006195 26 18 1,000 7,766E-03 0,08465529 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 1,000 7,766E-03 0,08425597 ! negative regulation of response to stimulus GO:0048585 80 56 2,000 8,359E-03 0,09025844 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 8,638E-03 0,09283714 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 1,000 8,638E-03 0,09240534 ! response to alkaloid GO:0043279 32 19 1,000 8,638E-03 0,09197754 ! sex determination GO:0007530 29 19 1,000 8,638E-03 0,09155368 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 1,000 8,638E-03 0,09113371 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 8,638E-03 0,09071757 ! protein stabilization GO:0050821 26 19 1,000 8,638E-03 0,09030522 ! response to starvation GO:0042594 30 19 1,000 8,638E-03 0,0898966 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 1,000 9,551E-03 0,09895451 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 1,000 9,551E-03 0,09851077 ! regulation of ARF GTPase activity GO:0032312 31 20 1,000 9,551E-03 0,09807099 ! positive regulation of B cell activation GO:0050871 31 20 1,000 9,551E-03 0,09763512 ! lung development GO:0030324 94 59 2,000 9,646E-03 0,09816996 ! phosphoinositide metabolic process GO:0030384 87 60 2,000 0,01009967 0,10233142 ! regulation of heart contraction GO:0008016 91 60 2,000 0,01009967 0,1018826 ! protein amino acid acylation GO:0043543 37 21 1,000 0,01050566 0,10551533 ! activation of pro-apoptotic gene products GO:0008633 36 21 1,000 0,01050566 0,10505657 ! purine ribonucleoside metabolic process GO:0046128 28 21 1,000 0,01050566 0,10460178 GO:0042278|purine nucleoside metabolic process, ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 0,01050566 0,10415091 ! nerve-nerve synaptic transmission GO:0007270 36 21 1,000 0,01050566 0,10370391 ! meiosis GO:0007126 96 61 2,000 0,01056528 0,10384679 GO:0051327|M phase of meiotic cell cycle, ! respiratory tube development GO:0030323 99 62 2,000 0,01104317 0,10808211 ! meiotic cell cycle GO:0051321 97 62 2,000 0,01104317 0,10762413 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 0,01150043 0,11160751 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 0,01150043 0,11113857 GO:0010810|regulation of cell-substrate adhesion, ! respiratory system development GO:0060541 100 64 2,000 0,01203599 0,11582754 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 0,01253493 0,12012637 ! myelination GO:0042552 35 23 1,000 0,01253493 0,11962792 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 0,01253493 0,11913359 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 0,01253493 0,11864333 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 0,01253493 0,11815709 ! group transfer coenzyme metabolic process GO:0006752 28 23 1,000 0,01253493 0,11767481 ! negative regulation of catabolic process GO:0009895 34 23 1,000 0,01253493 0,11719646 ! regulation of caspase activity GO:0043281 97 65 2,000 0,01255102 0,11687187 ! insulin receptor signaling pathway GO:0008286 40 24 1,000 0,01360852 0,12620803 ! receptor metabolic process GO:0043112 37 24 1,000 0,01360852 0,12570117 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 0,01360852 0,12519837 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 0,01361855 0,12479153 ! learning or memory GO:0007611 123 68 2,000 0,01417113 0,12933972 ! protein amino acid alkylation GO:0008213 39 25 1,000 0,01472058 0,13382341 GO:0006479|protein amino acid methylation, ! male gonad development GO:0008584 33 25 1,000 0,01472058 0,13329655 ! iron ion homeostasis GO:0055072 39 25 1,000 0,01472058 0,13277382 ! positive regulation of nuclear division GO:0051785 39 25 1,000 0,01472058 0,13225517 GO:0045840|positive regulation of mitosis, ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 0,01587047 0,14203148 ! phosphoinositide-mediated signaling GO:0048015 109 71 2,000 0,01590456 0,14178487 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 2,000 0,01590456 0,14123744 ! lymphocyte differentiation GO:0030098 113 71 2,000 0,01590456 0,14069422 ! regulation of peptidase activity GO:0052547 106 72 2,000 0,0165077 0,14547017 ! negative regulation of protein transport GO:0051224 49 27 1,000 0,0170576 0,14974229 ! mitochondrion organization GO:0007005 104 73 2,000 0,01712355 0,14974965 ! erythrocyte differentiation GO:0030218 38 28 1,000 0,01828134 0,15926929 ! ensheathment of neurons GO:0007272 43 28 1,000 0,01828134 0,15866827 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 1,000 0,01828134 0,15807178 ! regulation of ligase activity GO:0051340 114 75 2,000 0,01839344 0,15844538 ! regulation of protein transport GO:0051223 114 76 2,000 0,01904753 0,16346758 GO:0070201|regulation of establishment of protein localization, ! regulation of protein import into nucleus GO:0042306 53 29 1,000 0,01954111 0,16708009 ! sex differentiation GO:0007548 105 77 2,000 0,01971439 0,16793738 ! spindle organization GO:0007051 37 30 1,000 0,02083629 0,17683936 ! hindbrain development GO:0030902 45 30 1,000 0,02083629 0,17618922 ! regulation of microtubule-based process GO:0032886 58 30 1,000 0,02083629 0,17554383 ! response to heat GO:0009408 41 30 1,000 0,02083629 0,17490316 ! cellular respiration GO:0045333 107 79 2,000 0,02108648 0,17635965 ! oxidative phosphorylation GO:0006119 105 79 2,000 0,02108648 0,17572066 ! T cell activation GO:0042110 134 79 2,000 0,02108648 0,17508629 ! forebrain development GO:0030900 131 80 2,000 0,02179172 0,18029124 ! mammary gland development GO:0030879 57 31 1,000 0,02216631 0,18273301 ! glial cell differentiation GO:0010001 55 31 1,000 0,02216631 0,18208039 ! maintenance of protein location in cell GO:0032507 60 31 1,000 0,02216631 0,18143242 ! segmentation GO:0035282 41 31 1,000 0,02216631 0,18078904 ! metanephros development GO:0001656 58 31 1,000 0,02216631 0,18015021 ! response to mechanical stimulus GO:0009612 43 31 1,000 0,02216631 0,17951588 ! cell fate specification GO:0001708 37 31 1,000 0,02216631 0,178886 ! regulation of cell cycle process GO:0010564 122 81 2,000 0,02250977 0,18102265 ! ossification GO:0001503 134 82 2,000 0,02324063 0,18624893 GO:0060348|bone development, ! mitotic sister chromatid segregation GO:0000070 45 32 1,000 0,02353058 0,18791783 ! meiosis I GO:0007127 52 32 1,000 0,02353058 0,18726759 ! regulation of synaptic plasticity GO:0048167 52 32 1,000 0,02353058 0,18662184 ! regulation of ARF protein signal transduction GO:0032012 51 32 1,000 0,02353058 0,18598053 ! peripheral nervous system development GO:0007422 53 32 1,000 0,02353058 0,18534361 ! calcium-mediated signaling GO:0019722 50 32 1,000 0,02353058 0,18471104 ! regulation of cell adhesion GO:0030155 159 83 2,000 0,02398429 0,18763217 ! regulation of defense response GO:0031347 117 84 2,000 0,02474074 0,19289393 ! microtubule cytoskeleton organization GO:0000226 120 84 2,000 0,02474074 0,19224226 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 1,000 0,02492853 0,19304922 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 0,02492853 0,19240141 ! negative regulation of cell adhesion GO:0007162 67 33 1,000 0,02492853 0,19175793 ! sister chromatid segregation GO:0000819 46 33 1,000 0,02492853 0,19111873 ! ear morphogenesis GO:0042471 42 33 1,000 0,02492853 0,19048379 ! nucleotide catabolic process GO:0009166 46 33 1,000 0,02492853 0,18985305 ! cytokinesis GO:0000910 52 33 1,000 0,02492853 0,18922647 ! regulation of DNA metabolic process GO:0051052 135 85 2,000 0,02550999 0,19300325 ! positive regulation of MAP kinase activity GO:0043406 121 85 2,000 0,02550999 0,19237045 ! regulation of protein localization GO:0032880 132 85 2,000 0,02550999 0,19174179 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 0,02635959 0,19748228 ! development of primary male sexual characteristics GO:0046546 44 34 1,000 0,02635959 0,1968411 ! erythrocyte homeostasis GO:0034101 45 34 1,000 0,02635959 0,19620408 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 0,02635959 0,19557116 ! skeletal muscle tissue development GO:0007519 123 87 2,000 0,02708684 0,2003207 GO:0060538|skeletal muscle organ development, ! regulation of action potential in neuron GO:0019228 54 35 1,000 0,0278232 0,20510693 ! maintenance of protein location GO:0045185 65 35 1,000 0,0278232 0,20445164 ! glycogen metabolic process GO:0005977 48 35 1,000 0,0278232 0,20380052 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,0278232 0,20315353 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! reproductive developmental process GO:0003006 127 89 2,000 0,02871474 0,20899966 ! regulation of T cell activation GO:0050863 128 89 2,000 0,02871474 0,20834036 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,0293188 0,21205425 GO:0090047|positive regulation of transcription regulator activity, ! glucan metabolic process GO:0044042 49 36 1,000 0,0293188 0,2113895 GO:0006073|cellular glucan metabolic process, ! leukocyte differentiation GO:0002521 143 90 2,000 0,02954779 0,21237472 ! learning GO:0007612 67 37 1,000 0,03084585 0,2210139 ! ribonucleoside metabolic process GO:0009119 48 37 1,000 0,03084585 0,22032753 ! glycerophospholipid metabolic process GO:0006650 130 92 2,000 0,031252 0,22253748 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 1,000 0,0324038 0,23002701 ! gliogenesis GO:0042063 71 38 1,000 0,0324038 0,22931923 ! striated muscle cell differentiation GO:0051146 54 38 1,000 0,0324038 0,2286158 ! mesenchymal cell development GO:0014031 64 38 1,000 0,0324038 0,22791667 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 1,000 0,0324038 0,2272218 ! maintenance of location in cell GO:0051651 69 38 1,000 0,0324038 0,22653116 ! electron transport chain GO:0022900 123 94 2,000 0,03300689 0,23004802 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 1,000 0,03399212 0,23619903 ! male sex differentiation GO:0046661 53 39 1,000 0,03399212 0,23548759 ! chromatin remodeling GO:0006338 68 39 1,000 0,03399212 0,23478042 ! synapse organization GO:0050808 55 39 1,000 0,03399212 0,23407748 ! regulation of response to external stimulus GO:0032101 139 96 2,000 0,03481224 0,23900942 ! response to light stimulus GO:0009416 153 96 2,000 0,03481224 0,23829809 ! detection of stimulus involved in sensory perception GO:0050906 50 40 1,000 0,03561027 0,24303748 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 0,03561027 0,24231843 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,03663635 0,24856523 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,03663635 0,24783415 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,03663635 0,24710737 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,03663635 0,24638483 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,03663635 0,24566651 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03663635 0,24495236 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,03663635 0,24424235 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,03663635 0,24353645 ! sleep GO:0030431 11 5 0,000 0,03663635 0,24283462 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,03663635 0,24213681 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,03663635 0,24144301 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,03663635 0,24075318 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,03663635 0,24006727 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,03663635 0,23938526 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,03663635 0,23870711 ! tongue development GO:0043586 6 5 0,000 0,03663635 0,2380328 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,03663635 0,23736229 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,03663635 0,23669554 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,03663635 0,23603253 ! cobalt ion transport GO:0006824 9 5 0,000 0,03663635 0,23537322 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,03663635 0,23471758 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,03663635 0,23406559 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,03663635 0,23341721 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,03663635 0,23277241 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,03663635 0,23213116 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,03663635 0,23149344 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,03663635 0,23085921 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,03663635 0,23022845 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,03663635 0,22960112 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03663635 0,22897721 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03663635 0,22835667 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,03663635 0,22773949 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,03663635 0,22712564 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,03663635 0,22651508 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03663635 0,22590781 ! malate metabolic process GO:0006108 7 5 0,000 0,03663635 0,22530377 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,03663635 0,22470296 ! behavioral response to pain GO:0048266 7 5 0,000 0,03663635 0,22410535 ! clathrin coat assembly GO:0048268 11 5 0,000 0,03663635 0,22351091 ! phototransduction, visible light GO:0007603 6 5 0,000 0,03663635 0,22291961 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03663635 0,22233143 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,03663635 0,22174635 ! mating behavior GO:0007617 6 5 0,000 0,03663635 0,22116433 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,03663635 0,22058537 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,03663635 0,22000943 ! rhythmic behavior GO:0007622 12 5 0,000 0,03663635 0,21943649 ! copulation GO:0007620 7 5 0,000 0,03663635 0,21886652 ! glial cell fate commitment GO:0021781 12 5 0,000 0,03663635 0,21829951 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,03663635 0,21773543 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,03663635 0,21717426 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,03663635 0,21661597 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,03663635 0,21606054 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,03663635 0,21550796 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,03663635 0,21495819 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,03663635 0,21441123 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03663635 0,21386703 ! response to protozoan GO:0001562 9 5 0,000 0,03663635 0,2133256 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,03663635 0,2127869 ! lymph vessel development GO:0001945 7 5 0,000 0,03663635 0,21225091 ! endochondral ossification GO:0001958 12 5 0,000 0,03663635 0,21171762 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,03663635 0,211187 ! parathyroid gland development GO:0060017 8 5 0,000 0,03663635 0,21065903 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,03663635 0,21013369 ! anagen GO:0042640 6 5 0,000 0,03663635 0,20961097 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,03663635 0,20909085 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,03663635 0,2085733 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,03663635 0,2080583 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,03663635 0,20754584 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,03663635 0,2070359 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,03663635 0,20652846 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,03663635 0,2060235 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,03663635 0,205521 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,03663635 0,20502095 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,03663635 0,20452333 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,03663635 0,20402812 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,03663635 0,20353529 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,03663635 0,20304485 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,03663635 0,20255676 ! ovulation GO:0030728 6 5 0,000 0,03663635 0,20207101 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,03663635 0,20158759 GO:0033135|regulation of peptidyl-serine phosphorylation, ! valine metabolic process GO:0006573 8 5 0,000 0,03663635 0,20110647 ! response to pH GO:0009268 9 5 0,000 0,03663635 0,20062765 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,03663635 0,2001511 ! proline biosynthetic process GO:0006561 6 5 0,000 0,03663635 0,1996768 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03663635 0,19920476 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,03663635 0,19873493 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03663635 0,19826732 ! polyol catabolic process GO:0046174 7 5 0,000 0,03663635 0,19780191 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03663635 0,19733867 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03663635 0,1968776 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03663635 0,19641868 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,03663635 0,19596189 ! nerve growth factor processing GO:0032455 7 5 0,000 0,03663635 0,19550722 ! urea metabolic process GO:0019627 6 5 0,000 0,03663635 0,19505466 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,03663635 0,19460418 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03663635 0,19415579 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,03663635 0,19370945 ! neutrophil activation GO:0042119 5 5 0,000 0,03663635 0,19326516 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,03663635 0,19282291 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,03663635 0,19238267 ! response to food GO:0032094 5 5 0,000 0,03663635 0,19194445 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,03663635 0,19150821 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03663635 0,19107395 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,03663635 0,19064166 ! forebrain neuron development GO:0021884 7 5 0,000 0,03663635 0,19021131 ! melanosome organization GO:0032438 7 5 0,000 0,03663635 0,18978291 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,03663635 0,18935643 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03663635 0,18893186 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,03663635 0,1885092 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03663635 0,18808842 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,03663635 0,18766951 ! nucleoside transport GO:0015858 6 5 0,000 0,03663635 0,18725247 ! nucleoside salvage GO:0043174 7 5 0,000 0,03663635 0,18683728 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,03663635 0,18642392 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03663635 0,18601239 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,03663635 0,18560267 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,03663635 0,18519475 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03663635 0,18478862 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03663635 0,18438427 ! depyrimidination GO:0045008 8 5 0,000 0,03663635 0,18398168 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,03663635 0,18358085 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,03663635 0,18318176 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,03663635 0,18278441 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03663635 0,18238877 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,03663635 0,18199484 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,03663635 0,18160261 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,03663635 0,18121207 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,03663635 0,1808232 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,03663635 0,180436 ! monocyte differentiation GO:0030224 8 5 0,000 0,03663635 0,18005045 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,03663635 0,17966655 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03663635 0,17928428 ! centrosome duplication GO:0051298 5 5 0,000 0,03663635 0,17890363 ! response to UV-C GO:0010225 6 5 0,000 0,03663635 0,1785246 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,03663635 0,17814717 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,03663635 0,17777133 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,03663635 0,17739708 ! regulation of dendrite development GO:0050773 12 5 0,000 0,03663635 0,17702439 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,03663635 0,17665327 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03663635 0,17628371 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,03663635 0,17591568 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,03663635 0,17554919 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,03663635 0,17518422 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,03663635 0,17482077 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,03663635 0,17445882 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,03663635 0,17409837 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,03663635 0,17373941 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03663635 0,17338192 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,03663635 0,1730259 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03663635 0,17267134 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03663635 0,17231822 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,03663635 0,17196655 ! neural tube patterning GO:0021532 6 5 0,000 0,03663635 0,17161632 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,03663635 0,1712675 ! histone demethylation GO:0016577 9 5 0,000 0,03663635 0,1709201 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03663635 0,17057411 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03663635 0,17022952 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,03663635 0,16988631 ! enteric nervous system development GO:0048484 8 5 0,000 0,03663635 0,16954449 ! establishment of planar polarity GO:0001736 6 5 0,000 0,03663635 0,16920404 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,03663635 0,16886495 ! muscle cell proliferation GO:0033002 8 5 0,000 0,03663635 0,16852722 ! transcription termination GO:0006353 8 5 0,000 0,03663635 0,16819084 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,03663635 0,1678558 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,03663635 0,16752209 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,03663635 0,16718971 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,03663635 0,16685864 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,03663635 0,16652888 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03663635 0,16620042 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03663635 0,16587325 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,03663635 0,16554737 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,03663635 0,16522277 ! apical protein localization GO:0045176 6 5 0,000 0,03663635 0,16489944 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,03663635 0,16457737 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,03663635 0,16425655 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03663635 0,16393699 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03663635 0,16361866 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,03663635 0,16330157 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,03663635 0,16298571 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,03663635 0,16267106 ! glial cell migration GO:0008347 10 5 0,000 0,03663635 0,16235763 ! determination of adult lifespan GO:0008340 8 5 0,000 0,03663635 0,16204541 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,03663635 0,16173438 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03663635 0,16142454 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03663635 0,16111589 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,03663635 0,16080842 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,03663635 0,16050212 ! neural plate development GO:0001840 6 5 0,000 0,03663635 0,16019698 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,03663635 0,159893 ! regulation of sensory perception GO:0051931 6 5 0,000 0,03663635 0,15959017 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,03663635 0,15928849 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,03663635 0,15898795 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,03663635 0,15868853 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,03663635 0,15839025 ! sensory cilium assembly GO:0035058 6 5 0,000 0,03663635 0,15809308 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,03663635 0,15779703 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03663635 0,15750208 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,03663635 0,15720823 ! spindle assembly GO:0051225 5 5 0,000 0,03663635 0,15691548 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,03663635 0,15662381 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,03663635 0,15633323 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,03663635 0,15604373 ! organ regeneration GO:0031100 7 5 0,000 0,03663635 0,15575529 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,03663635 0,15546792 ! carnitine metabolic process GO:0009437 5 5 0,000 0,03663635 0,15518161 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,03663635 0,15489634 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,03663635 0,15461213 GO:0055081|anion homeostasis, ! epithelial cell differentiation GO:0030855 55 41 1,000 0,03725774 0,15694652 ! energy reserve metabolic process GO:0006112 59 41 1,000 0,03725774 0,15665959 ! endosome transport GO:0016197 71 41 1,000 0,03725774 0,15637372 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,03725774 0,15608888 ! biopolymer methylation GO:0043414 62 41 1,000 0,03725774 0,15580509 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 2,000 0,03761438 0,15701102 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 1,000 0,038934 0,16222498 ! positive regulation of binding GO:0051099 59 43 1,000 0,04063853 0,16902103 ! vesicle organization GO:0016050 79 43 1,000 0,04063853 0,16871594 ! response to insulin stimulus GO:0032868 63 43 1,000 0,04063853 0,16841195 ! methylation GO:0032259 64 43 1,000 0,04063853 0,16810905 ! detection of abiotic stimulus GO:0009582 58 44 1,000 0,04237085 0,17496042 ! regulation of action potential GO:0001508 71 44 1,000 0,04237085 0,17464687 ! tRNA transcription GO:0009304 11 6 0,000 0,04380219 0,18022367 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,04380219 0,17990184 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,04380219 0,17958116 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04380219 0,17926162 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,04380219 0,17894321 ! regulation of helicase activity GO:0051095 11 6 0,000 0,04380219 0,17862594 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,04380219 0,17830979 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,04380219 0,17799475 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,04380219 0,17768083 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,04380219 0,17736801 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,04380219 0,17705629 ! prostate gland development GO:0030850 9 6 0,000 0,04380219 0,17674566 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,04380219 0,17643613 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,04380219 0,17612767 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,04380219 0,17582029 GO:0021872|generation of neurons in the forebrain, ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,04380219 0,17551399 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,04380219 0,17520875 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,04380219 0,17490456 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,04380219 0,17460144 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! neuron adhesion GO:0007158 9 6 0,000 0,04380219 0,17429936 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,04380219 0,17399832 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,04380219 0,17369833 ! signal peptide processing GO:0006465 8 6 0,000 0,04380219 0,17339936 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,04380219 0,17310142 ! mRNA stabilization GO:0048255 15 6 0,000 0,04380219 0,17280451 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,04380219 0,17250861 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,04380219 0,17221372 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,04380219 0,17191984 ! opsonization GO:0008228 8 6 0,000 0,04380219 0,17162697 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,04380219 0,17133508 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,04380219 0,17104419 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,04380219 0,17075429 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,04380219 0,17046536 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,04380219 0,17017741 ! photoreceptor cell development GO:0042461 10 6 0,000 0,04380219 0,16989044 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,04380219 0,16960443 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,04380219 0,16931938 ! mechanosensory behavior GO:0007638 8 6 0,000 0,04380219 0,16903528 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,04380219 0,16875214 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,04380219 0,16846995 ! response to interferon-gamma GO:0034341 12 6 0,000 0,04380219 0,1681887 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,04380219 0,16790838 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04380219 0,167629 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,04380219 0,16735055 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,04380219 0,16707302 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,04380219 0,16679641 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,04380219 0,16652071 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,04380219 0,16624592 ! thymic T cell selection GO:0045061 12 6 0,000 0,04380219 0,16597204 ! protein lipoylation GO:0009249 10 6 0,000 0,04380219 0,16569906 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,04380219 0,16542698 ! pigment granule organization GO:0048753 11 6 0,000 0,04380219 0,16515579 ! drug transport GO:0015893 6 6 0,000 0,04380219 0,16488548 ! cysteine metabolic process GO:0006534 7 6 0,000 0,04380219 0,16461606 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,04380219 0,16434752 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,04380219 0,16407985 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04380219 0,16381306 ! histidine metabolic process GO:0006547 6 6 0,000 0,04380219 0,16354712 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,04380219 0,16328206 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,04380219 0,16301785 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,04380219 0,16275449 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,04380219 0,16249198 ! adenohypophysis development GO:0021984 10 6 0,000 0,04380219 0,16223032 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,04380219 0,1619695 ! hyperosmotic response GO:0006972 8 6 0,000 0,04380219 0,16170952 ! microtubule nucleation GO:0007020 10 6 0,000 0,04380219 0,16145037 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,04380219 0,16119205 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,04380219 0,16093455 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,04380219 0,16067788 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,04380219 0,16042202 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,04380219 0,16016698 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 0,04380219 0,15991274 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,04380219 0,15965932 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,04380219 0,15940669 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,04380219 0,15915486 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,04380219 0,15890383 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,04380219 0,15865359 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,04380219 0,15840413 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04380219 0,15815546 ! neuron apoptosis GO:0051402 8 6 0,000 0,04380219 0,15790757 ! organic alcohol transport GO:0015850 9 6 0,000 0,04380219 0,15766045 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,04380219 0,15741411 ! T cell mediated immunity GO:0002456 12 6 0,000 0,04380219 0,15716853 ! male sex determination GO:0030238 9 6 0,000 0,04380219 0,15692372 ! carnitine transport GO:0015879 8 6 0,000 0,04380219 0,15667967 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,04380219 0,15643638 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,04380219 0,15619384 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,04380219 0,15595206 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,04380219 0,15571102 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,04380219 0,15547072 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,04380219 0,15523117 ! parturition GO:0007567 12 6 0,000 0,04380219 0,15499235 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,04380219 0,15475427 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,04380219 0,15451692 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,04380219 0,15428029 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,04380219 0,15404439 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,04380219 0,1538092 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,04380219 0,15357474 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,04380219 0,15334099 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,04380219 0,15310795 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,04380219 0,15287561 ! macrophage differentiation GO:0030225 10 6 0,000 0,04380219 0,15264398 ! astrocyte development GO:0014002 14 6 0,000 0,04380219 0,15241305 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,04380219 0,15218282 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,04380219 0,15195329 ! interaction with symbiont GO:0051702 8 6 0,000 0,04380219 0,15172444 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04380219 0,15149628 ! eating behavior GO:0042755 6 6 0,000 0,04380219 0,15126881 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,04380219 0,15104202 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,04380219 0,15081591 ! response to copper ion GO:0046688 9 6 0,000 0,04380219 0,15059048 ! DNA topological change GO:0006265 8 6 0,000 0,04380219 0,15036571 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,04380219 0,15014162 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,04380219 0,1499182 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04380219 0,14969544 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04380219 0,14947334 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,04380219 0,14925189 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,04380219 0,14903111 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,04380219 0,14881097 ! gas homeostasis GO:0033483 11 6 0,000 0,04380219 0,14859149 ! hair follicle maturation GO:0048820 7 6 0,000 0,04380219 0,14837265 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,04380219 0,14815445 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,04380219 0,1479369 ! Schwann cell development GO:0014044 14 6 0,000 0,04380219 0,14771998 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,04380219 0,1475037 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,04380219 0,14728805 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04380219 0,14707303 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,04380219 0,14685864 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,04380219 0,14664487 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,04380219 0,14643173 ! histone ubiquitination GO:0016574 7 6 0,000 0,04380219 0,1462192 ! regulation of meiosis GO:0040020 10 6 0,000 0,04380219 0,14600729 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,04380219 0,14579599 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,04380219 0,1455853 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,04380219 0,14537522 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,04380219 0,14516575 ! membrane to membrane docking GO:0022614 12 6 0,000 0,04380219 0,14495688 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,04380219 0,1447486 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,04380219 0,14454093 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,04380219 0,14433385 ! receptor internalization GO:0031623 9 6 0,000 0,04380219 0,14412737 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,04380219 0,14392147 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,04380219 0,14371616 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,04380219 0,14351144 ! protein deubiquitination GO:0016579 8 6 0,000 0,04380219 0,1433073 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,04380219 0,14310373 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,04380219 0,14290075 ! axonal fasciculation GO:0007413 9 6 0,000 0,04380219 0,14269834 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,04380219 0,1424965 ! thiamin metabolic process GO:0006772 6 6 0,000 0,04380219 0,14229524 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,04380219 0,14209454 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,04380219 0,14189441 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,04380219 0,14169484 ! progesterone metabolic process GO:0042448 8 6 0,000 0,04380219 0,14149583 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,04380219 0,14129738 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,04380219 0,14109948 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,04380219 0,14090214 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,04380219 0,14070535 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,04380219 0,14050911 ! adult feeding behavior GO:0008343 6 6 0,000 0,04380219 0,14031341 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,04380219 0,14011826 ! blastocyst growth GO:0001832 15 6 0,000 0,04380219 0,13992365 ! pigment granule transport GO:0051904 12 6 0,000 0,04380219 0,13972958 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,04380219 0,13953605 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,04380219 0,13934306 ! catecholamine transport GO:0051937 7 6 0,000 0,04380219 0,13915059 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,04380219 0,13895866 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,04380219 0,13876726 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,04380219 0,13857638 ! protein prenylation GO:0018342 10 6 0,000 0,04380219 0,13838603 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04380219 0,1381962 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,04380219 0,13800689 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,04380219 0,1378181 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,04380219 0,13762982 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,04380219 0,13744206 ! regulation of translational initiation GO:0006446 64 45 1,000 0,04413044 0,13828339 ! chloride transport GO:0006821 67 48 1,000 0,04956794 0,15511056 ! response to temperature stimulus GO:0009266 62 48 1,000 0,04956794 0,15489981 ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 0,04956794 0,15468964 ! regulation of DNA replication GO:0006275 75 48 1,000 0,04956794 0,15448003 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,05091513 0,15846385 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,05091513 0,15824971 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,05091513 0,15803615 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,05091513 0,15782316 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,05091513 0,15761075 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,05091513 0,15739891 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,05091513 0,15718763 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,05091513 0,15697693 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,05091513 0,15676678 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,05091513 0,1565572 ! reproductive behavior GO:0019098 12 7 0,000 0,05091513 0,15634818 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,05091513 0,15613972 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,05091513 0,15593181 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,05091513 0,15572445 ! oligopeptide transport GO:0006857 11 7 0,000 0,05091513 0,15551765 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,05091513 0,15531139 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,05091513 0,15510568 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,05091513 0,15490051 ! RNA methylation GO:0001510 11 7 0,000 0,05091513 0,15469589 ! pericardium development GO:0060039 8 7 0,000 0,05091513 0,1544918 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,05091513 0,15428826 ! fibril organization GO:0043206 13 7 0,000 0,05091513 0,15408525 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,05091513 0,15388277 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,05091513 0,15368082 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,05091513 0,15347941 ! lipoprotein transport GO:0042953 9 7 0,000 0,05091513 0,15327852 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,05091513 0,15307815 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,05091513 0,15287831 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,05091513 0,15267899 ! estrogen metabolic process GO:0008210 14 7 0,000 0,05091513 0,15248019 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,05091513 0,15228191 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,05091513 0,15208414 ! chemosensory behavior GO:0007635 9 7 0,000 0,05091513 0,15188688 ! microtubule bundle formation GO:0001578 8 7 0,000 0,05091513 0,15169014 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,05091513 0,1514939 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,05091513 0,15129818 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,05091513 0,15110295 ! leukocyte degranulation GO:0043299 10 7 0,000 0,05091513 0,15090823 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,05091513 0,15071401 ! reflex GO:0060004 12 7 0,000 0,05091513 0,15052029 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,05091513 0,15032707 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,05091513 0,15013434 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,05091513 0,14994211 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,05091513 0,14975037 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,05091513 0,14955912 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,05091513 0,14936835 ! spinal cord patterning GO:0021511 7 7 0,000 0,05091513 0,14917807 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,05091513 0,14898828 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,05091513 0,14879897 ! adrenal gland development GO:0030325 17 7 0,000 0,05091513 0,14861014 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,05091513 0,14842178 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,05091513 0,14823391 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,05091513 0,14804651 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,05091513 0,14785958 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,05091513 0,14767312 ! endosome organization GO:0007032 10 7 0,000 0,05091513 0,14748714 ! thyroid hormone generation GO:0006590 11 7 0,000 0,05091513 0,14730162 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,05091513 0,14711657 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,05091513 0,14693198 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,05091513 0,14674785 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,05091513 0,14656419 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,05091513 0,14638098 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,05091513 0,14619824 ! galactose metabolic process GO:0006012 10 7 0,000 0,05091513 0,14601594 ! vesicle fusion GO:0006906 15 7 0,000 0,05091513 0,14583411 ! intracellular pH reduction GO:0051452 10 7 0,000 0,05091513 0,14565272 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,05091513 0,14547179 ! organ growth GO:0035265 11 7 0,000 0,05091513 0,1452913 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,05091513 0,14511126 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,05091513 0,14493167 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,05091513 0,14475252 ! retinol metabolic process GO:0042572 9 7 0,000 0,05091513 0,14457381 ! behavioral fear response GO:0001662 13 7 0,000 0,05091513 0,14439555 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,05091513 0,14421772 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,05091513 0,14404033 ! rRNA modification GO:0000154 12 7 0,000 0,05091513 0,14386338 ! protein heterooligomerization GO:0051291 10 7 0,000 0,05091513 0,14368686 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,05091513 0,14351077 ! response to UV-B GO:0010224 11 7 0,000 0,05091513 0,14333511 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,05091513 0,14315989 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,05091513 0,14298509 ! intermediate filament organization GO:0045109 11 7 0,000 0,05091513 0,14281072 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,05091513 0,14263677 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,05091513 0,14246325 ! fibrinolysis GO:0042730 9 7 0,000 0,05091513 0,14229014 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,05091513 0,14211746 ! B cell lineage commitment GO:0002326 17 7 0,000 0,05091513 0,1419452 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,05091513 0,14177335 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,05091513 0,14160192 ! response to tropane GO:0014073 13 7 0,000 0,05091513 0,1414309 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,05091513 0,1412603 ! melanosome localization GO:0032400 10 7 0,000 0,05091513 0,14109011 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,05091513 0,14092032 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,05091513 0,14075095 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,05091513 0,14058198 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,05091513 0,14041341 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,05091513 0,14024525 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,05091513 0,1400775 ! mast cell activation GO:0045576 9 7 0,000 0,05091513 0,13991014 ! multicellular organismal aging GO:0010259 11 7 0,000 0,05091513 0,13974318 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,05091513 0,13957662 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,05091513 0,13941046 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,05091513 0,13924469 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,05091513 0,13907932 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,05091513 0,13891434 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,05091513 0,13874975 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,05091513 0,13858555 ! T cell lineage commitment GO:0002360 12 7 0,000 0,05091513 0,13842173 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,05091513 0,13825831 GO:0002714|positive regulation of B cell mediated immunity, ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,05091513 0,13809527 ! regulation of lipid transport GO:0032368 13 7 0,000 0,05091513 0,13793261 ! response to tumor cell GO:0002347 12 7 0,000 0,05091513 0,13777034 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,05091513 0,13760845 ! neuroblast proliferation GO:0007405 13 7 0,000 0,05091513 0,13744693 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,05091513 0,1372858 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,05091513 0,13712504 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,05091513 0,13696466 ! diuresis GO:0030146 12 7 0,000 0,05091513 0,13680466 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,05091513 0,13664503 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,05091513 0,13648577 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,05091513 0,13632688 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,05091513 0,13616836 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,05091513 0,13601021 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,05091513 0,13585242 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,05091513 0,135695 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,05091513 0,13553795 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,05091513 0,13538126 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,05091513 0,13522493 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,05091513 0,13506896 ! lymph node development GO:0048535 9 7 0,000 0,05091513 0,13491335 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,05091513 0,1347581 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,05091513 0,1346032 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,05091513 0,13444867 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,05091513 0,13429448 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,05091513 0,13414065 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,05091513 0,13398717 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,05091513 0,13383404 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,05091513 0,13368126 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,05091513 0,13352883 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,05091513 0,13337675 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,05091513 0,13322501 ! muscle adaptation GO:0043500 12 7 0,000 0,05091513 0,13307362 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,05091513 0,13292257 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,05091513 0,13277187 ! retina homeostasis GO:0001895 9 7 0,000 0,05091513 0,1326215 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,05091513 0,13247148 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,05091513 0,13232179 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,05091513 0,13217245 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,05091513 0,13202344 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,05091513 0,13187476 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,05091513 0,13172642 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,05091513 0,13157841 ! regulation of angiogenesis GO:0045765 94 49 1,000 0,05143174 0,13276432 ! germ cell development GO:0007281 68 49 1,000 0,05143174 0,13261548 ! heterocycle catabolic process GO:0046700 72 49 1,000 0,05143174 0,13246697 ! maintenance of location GO:0051235 84 49 1,000 0,05143174 0,1323188 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,0533204 0,1370245 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,05523346 0,14178231 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 0,05523346 0,14162425 ! positive regulation of cell migration GO:0030335 92 51 1,000 0,05523346 0,14146654 ! regulation of protein catabolic process GO:0042176 77 51 1,000 0,05523346 0,14130918 ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,05523346 0,14115217 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,05717044 0,14594009 ! aging GO:0007568 79 52 1,000 0,05717044 0,14577829 ! establishment of organelle localization GO:0051656 85 52 1,000 0,05717044 0,14561685 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,05797556 0,14750418 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,05797556 0,14734119 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,05797556 0,14717856 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,05797556 0,14701629 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,05797556 0,14685438 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,05797556 0,14669283 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,05797556 0,14653163 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,05797556 0,14637078 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,05797556 0,14621028 ! phosphate transport GO:0006817 10 8 0,000 0,05797556 0,14605014 ! N-glycan processing GO:0006491 12 8 0,000 0,05797556 0,14589035 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,05797556 0,14573091 ! UTP metabolic process GO:0046051 8 8 0,000 0,05797556 0,14557181 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,05797556 0,14541306 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,05797556 0,14525466 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,05797556 0,1450966 ! succinate metabolic process GO:0006105 14 8 0,000 0,05797556 0,14493889 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,05797556 0,14478152 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,05797556 0,14462449 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,05797556 0,1444678 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,05797556 0,14431145 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,05797556 0,14415544 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05797556 0,14399976 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,05797556 0,14384442 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,05797556 0,14368942 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,05797556 0,14353475 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,05797556 0,14338041 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,05797556 0,1432264 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,05797556 0,14307272 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,05797556 0,14291938 ! astrocyte differentiation GO:0048708 16 8 0,000 0,05797556 0,14276636 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,05797556 0,14261367 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,05797556 0,1424613 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,05797556 0,14230926 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,05797556 0,14215755 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,05797556 0,14200615 ! melanin metabolic process GO:0006582 12 8 0,000 0,05797556 0,14185508 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,05797556 0,14170434 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,05797556 0,14155391 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,05797556 0,1414038 ! macrophage activation GO:0042116 12 8 0,000 0,05797556 0,141254 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,05797556 0,14110453 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,05797556 0,14095537 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,05797556 0,14080653 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,05797556 0,140658 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,05797556 0,14050978 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,05797556 0,14036187 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,05797556 0,14021428 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,05797556 0,140067 ! ruffle organization GO:0031529 11 8 0,000 0,05797556 0,13992002 ! osteoblast development GO:0002076 13 8 0,000 0,05797556 0,13977335 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,05797556 0,13962699 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,05797556 0,13948094 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,05797556 0,13933519 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,05797556 0,13918975 GO:0007351|tripartite regional subdivision, ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,05797556 0,13904461 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,05797556 0,13889977 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,05797556 0,13875523 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,05797556 0,138611 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,05797556 0,13846706 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,05797556 0,13832342 ! oligodendrocyte development GO:0014003 8 8 0,000 0,05797556 0,13818008 ! segment specification GO:0007379 10 8 0,000 0,05797556 0,13803704 ! cellular extravasation GO:0045123 11 8 0,000 0,05797556 0,13789429 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,05797556 0,13775184 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,05797556 0,13760968 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,05797556 0,13746781 ! snRNA metabolic process GO:0016073 10 8 0,000 0,05797556 0,13732624 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,05797556 0,13718496 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,05797556 0,13704397 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,05797556 0,13690326 ! nucleosome disassembly GO:0006337 12 8 0,000 0,05797556 0,13676285 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,05797556 0,13662272 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,05797556 0,13648289 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,05797556 0,13634333 ! icosanoid secretion GO:0032309 12 8 0,000 0,05797556 0,13620406 GO:0050482|arachidonic acid secretion, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,05797556 0,13606508 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,05797556 0,13592638 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,05797556 0,13578796 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,05797556 0,13564983 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,05797556 0,13551197 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,05797556 0,1353744 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,05797556 0,1352371 ! sterol catabolic process GO:0016127 9 8 0,000 0,05797556 0,13510008 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,05797556 0,13496334 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,05797556 0,13482687 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,05797556 0,13469069 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,05797556 0,13455477 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,05797556 0,13441913 ! prophase GO:0051324 11 8 0,000 0,05797556 0,13428377 ! S phase GO:0051320 8 8 0,000 0,05797556 0,13414867 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,05797556 0,13401385 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,05797556 0,1338793 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,05797556 0,13374501 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,05797556 0,133611 ! hormone catabolic process GO:0042447 13 8 0,000 0,05797556 0,13347726 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,05797556 0,13334378 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,05797556 0,13321057 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,05797556 0,13307762 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,05797556 0,13294494 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,05797556 0,13281253 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,05797556 0,13268038 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,05797556 0,13254849 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,05797556 0,13241686 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,05797556 0,1322855 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,05797556 0,13215439 ! lamellipodium assembly GO:0030032 9 8 0,000 0,05797556 0,13202354 ! regulation of embryonic development GO:0045995 16 8 0,000 0,05797556 0,13189296 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,05797556 0,13176263 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,05797556 0,13163256 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,05797556 0,13150274 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,0591309 0,13399121 ! kidney development GO:0001822 90 53 1,000 0,0591309 0,13385933 ! cell projection assembly GO:0030031 76 53 1,000 0,0591309 0,13372771 ! regulation of mitosis GO:0007088 84 54 1,000 0,06111439 0,13807771 GO:0051783|regulation of nuclear division, ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,06111439 0,1379422 ! detection of external stimulus GO:0009581 66 54 1,000 0,06111439 0,13780697 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,06111439 0,13767199 ! nucleoside metabolic process GO:0009116 69 55 1,000 0,06312046 0,14205193 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,06498386 0,14610253 ! regulation of developmental growth GO:0048638 13 9 0,000 0,06498386 0,14595985 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,06498386 0,14581745 ! telencephalon cell migration GO:0022029 16 9 0,000 0,06498386 0,14567533 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,06498386 0,14553348 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,06498386 0,14539191 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,06498386 0,14525062 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,06498386 0,1451096 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,06498386 0,14496885 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,06498386 0,14482838 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,06498386 0,14468818 ! GTP metabolic process GO:0046039 9 9 0,000 0,06498386 0,14454825 ! elastic fiber assembly GO:0048251 13 9 0,000 0,06498386 0,14440859 ! social behavior GO:0035176 14 9 0,000 0,06498386 0,1442692 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,06498386 0,14413008 ! artery development GO:0060840 19 9 0,000 0,06498386 0,14399122 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,06498386 0,14385264 ! regulation of glycolysis GO:0006110 15 9 0,000 0,06498386 0,14371432 ! response to pain GO:0048265 16 9 0,000 0,06498386 0,14357626 ! protein complex disassembly GO:0043241 17 9 0,000 0,06498386 0,14343847 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,06498386 0,14330095 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,06498386 0,14316369 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,06498386 0,14302669 ! lung alveolus development GO:0048286 17 9 0,000 0,06498386 0,14288995 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,06498386 0,14275347 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,06498386 0,14261726 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,06498386 0,1424813 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,06498386 0,14234561 ! ventral spinal cord development GO:0021517 11 9 0,000 0,06498386 0,14221017 ! protein targeting to ER GO:0045047 19 9 0,000 0,06498386 0,14207499 ! T cell selection GO:0045058 18 9 0,000 0,06498386 0,14194006 ! endoderm development GO:0007492 12 9 0,000 0,06498386 0,1418054 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,06498386 0,14167098 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,06498386 0,14153683 ! arginine catabolic process GO:0006527 10 9 0,000 0,06498386 0,14140292 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,06498386 0,14126927 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,06498386 0,14113587 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,06498386 0,14100272 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,06498386 0,14086983 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,06498386 0,14073718 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,06498386 0,14060479 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,06498386 0,14047264 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,06498386 0,14034074 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,06498386 0,14020909 ! mannose metabolic process GO:0006013 9 9 0,000 0,06498386 0,14007768 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,06498386 0,13994652 ! epithelial cell development GO:0002064 10 9 0,000 0,06498386 0,13981561 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,06498386 0,13968494 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,06498386 0,13955452 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,06498386 0,13942434 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,06498386 0,1392944 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,06498386 0,1391647 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,06498386 0,13903524 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,06498386 0,13890603 ! blastoderm segmentation GO:0007350 11 9 0,000 0,06498386 0,13877705 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,06498386 0,13864832 ! DNA ligation GO:0006266 14 9 0,000 0,06498386 0,13851982 ! response to amine stimulus GO:0014075 13 9 0,000 0,06498386 0,13839156 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,06498386 0,13826354 ! erythrocyte development GO:0048821 11 9 0,000 0,06498386 0,13813576 ! renal water homeostasis GO:0003091 14 9 0,000 0,06498386 0,13800821 ! postreplication repair GO:0006301 11 9 0,000 0,06498386 0,13788089 ! mRNA cleavage GO:0006379 13 9 0,000 0,06498386 0,13775381 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,06498386 0,13762697 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,06498386 0,13750036 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,06498386 0,13737398 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,06498386 0,13724783 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,06498386 0,13712192 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,06498386 0,13699623 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,06498386 0,13687078 ! acid secretion GO:0046717 14 9 0,000 0,06498386 0,13674555 ! musculoskeletal movement GO:0050881 11 9 0,000 0,06498386 0,13662056 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,06498386 0,13649579 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,06498386 0,13637125 ! purine base metabolic process GO:0006144 18 9 0,000 0,06498386 0,13624694 ! oocyte differentiation GO:0009994 12 9 0,000 0,06498386 0,13612285 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,06498386 0,13599899 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,06498386 0,13587535 ! spleen development GO:0048536 15 9 0,000 0,06498386 0,13575194 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,06498386 0,13562876 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,06498386 0,13550579 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,06498386 0,13538305 ! detection of calcium ion GO:0005513 13 9 0,000 0,06498386 0,13526053 ! blastocyst formation GO:0001825 12 9 0,000 0,06498386 0,13513824 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,06498386 0,13501616 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,06498386 0,1348943 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,06498386 0,13477267 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,06498386 0,13465125 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,06498386 0,13453005 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,06498386 0,13440907 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,06498386 0,13428831 ! prepulse inhibition GO:0060134 14 9 0,000 0,06498386 0,13416776 ! embryonic placenta development GO:0001892 12 9 0,000 0,06498386 0,13404743 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,06498386 0,13392732 ! insulin secretion GO:0030073 17 9 0,000 0,06498386 0,13380742 ! sequestering of metal ion GO:0051238 11 9 0,000 0,06498386 0,13368774 ! response to nicotine GO:0035094 16 9 0,000 0,06498386 0,13356826 ! establishment of cell polarity GO:0030010 12 9 0,000 0,06498386 0,13344901 ! nucleus localization GO:0051647 15 9 0,000 0,06498386 0,13332996 ! regulation of synapse organization GO:0050807 12 9 0,000 0,06498386 0,13321113 ! regulation of lipid metabolic process GO:0019216 84 56 1,000 0,06514868 0,13343006 ! positive regulation of cell motion GO:0051272 99 56 1,000 0,06514868 0,13331135 ! chromosome segregation GO:0007059 83 57 1,000 0,0671986 0,1373838 ! camera-type eye development GO:0043010 88 57 1,000 0,0671986 0,13726179 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 0,0671986 0,13714 ! developmental maturation GO:0021700 75 57 1,000 0,0671986 0,13701842 ! gonad development GO:0008406 79 57 1,000 0,0671986 0,13689706 ! regulation of cytokine biosynthetic process GO:0042035 76 58 1,000 0,0692698 0,14099162 ! actin filament organization GO:0007015 95 59 1,000 0,07136185 0,14512136 ! myeloid cell differentiation GO:0030099 85 59 1,000 0,07136185 0,14499316 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,07194043 0,14603971 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,07194043 0,14591093 ! neuron fate specification GO:0048665 11 10 0,000 0,07194043 0,14578237 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,07194043 0,14565404 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,07194043 0,14552594 ! thyroid gland development GO:0030878 19 10 0,000 0,07194043 0,14539806 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,07194043 0,14527041 ! synapsis GO:0007129 13 10 0,000 0,07194043 0,14514298 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,07194043 0,14501577 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,07194043 0,14488879 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,07194043 0,14476202 ! sulfate transport GO:0008272 12 10 0,000 0,07194043 0,14463548 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,07194043 0,14450916 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,07194043 0,14438307 ! androgen metabolic process GO:0008209 13 10 0,000 0,07194043 0,14425719 ! phospholipid efflux GO:0033700 16 10 0,000 0,07194043 0,14413153 ! hippocampus development GO:0021766 19 10 0,000 0,07194043 0,14400609 ! blood vessel remodeling GO:0001974 21 10 0,000 0,07194043 0,14388086 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,07194043 0,14375586 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,07194043 0,14363107 ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,07194043 0,1435065 ! pathogenesis GO:0009405 13 10 0,000 0,07194043 0,14338214 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,07194043 0,143258 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,07194043 0,14313408 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,07194043 0,14301037 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,07194043 0,14288687 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,07194043 0,14276358 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,07194043 0,14264051 ! melanocyte differentiation GO:0030318 15 10 0,000 0,07194043 0,14251765 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,07194043 0,142395 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,07194043 0,14227256 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,07194043 0,14215034 ! response to X-ray GO:0010165 16 10 0,000 0,07194043 0,14202832 ! B cell proliferation GO:0042100 14 10 0,000 0,07194043 0,14190651 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,07194043 0,14178491 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,07194043 0,14166352 ! forebrain cell migration GO:0021885 17 10 0,000 0,07194043 0,14154234 ! lipid digestion GO:0044241 15 10 0,000 0,07194043 0,14142136 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,07194043 0,14130059 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,07194043 0,14118003 ! UV protection GO:0009650 14 10 0,000 0,07194043 0,14105967 ! entry into host cell GO:0030260 20 10 0,000 0,07194043 0,14093952 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,07194043 0,14081957 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,07194043 0,14069982 ! negative regulation of ossification GO:0030279 19 10 0,000 0,07194043 0,14058028 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,07194043 0,14046094 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,07194043 0,14034181 ! regulation of bone resorption GO:0045124 24 10 0,000 0,07194043 0,14022288 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,07194043 0,14010414 ! regulation of organ growth GO:0046620 11 10 0,000 0,07194043 0,13998561 ! response to dsRNA GO:0043331 18 10 0,000 0,07194043 0,13986728 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,07194043 0,13974915 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,07194043 0,13963122 ! embryonic axis specification GO:0000578 12 10 0,000 0,07194043 0,13951348 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,07194043 0,13939595 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,07194043 0,13927861 ! cranial nerve development GO:0021545 12 10 0,000 0,07194043 0,13916147 ! fucose catabolic process GO:0019317 16 10 0,000 0,07194043 0,13904453 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,07194043 0,13892779 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,07194043 0,13881124 ! protein sumoylation GO:0016925 12 10 0,000 0,07194043 0,13869488 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,07194043 0,13857872 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,07194043 0,13846276 ! zymogen activation GO:0031638 14 10 0,000 0,07194043 0,13834698 ! salivary gland development GO:0007431 22 10 0,000 0,07194043 0,13823141 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,07194043 0,13811602 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,07194043 0,13800083 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,07194043 0,13788583 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,07194043 0,13777102 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,07194043 0,1376564 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,07194043 0,13754197 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,07194043 0,13742773 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,07194043 0,13731369 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,07194043 0,13719983 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,07194043 0,13708616 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,07194043 0,13697268 ! detection of bacterium GO:0016045 10 10 0,000 0,07194043 0,13685938 ! embryonic gut development GO:0048566 11 10 0,000 0,07194043 0,13674627 ! activation of innate immune response GO:0002218 10 10 0,000 0,07194043 0,13663335 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,07194043 0,13652062 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,07194043 0,13640807 ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,07194043 0,13629571 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,07194043 0,13618353 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,07194043 0,13607154 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 1,000 0,07347434 0,13885865 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,07347434 0,13874465 ! cell-matrix adhesion GO:0007160 114 61 1,000 0,07560685 0,14265444 ! urogenital system development GO:0001655 101 61 1,000 0,07560685 0,14253751 ! homeostasis of number of cells GO:0048872 84 61 1,000 0,07560685 0,14242077 ! negative regulation of ligase activity GO:0051352 91 61 1,000 0,07560685 0,14230422 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 0,07560685 0,14218786 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 0,07775897 0,14611572 ! organelle localization GO:0051640 96 62 1,000 0,07775897 0,14599644 ! rRNA transcription GO:0009303 17 11 0,000 0,07884564 0,14791596 ! respiratory burst GO:0045730 14 11 0,000 0,07884564 0,14779541 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,07884564 0,14767505 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,07884564 0,14755489 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,07884564 0,14743493 ! virus-host interaction GO:0019048 17 11 0,000 0,07884564 0,14731516 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,07884564 0,14719559 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,07884564 0,14707621 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,07884564 0,14695702 ! RNA polyadenylation GO:0043631 19 11 0,000 0,07884564 0,14683803 ! mating GO:0007618 14 11 0,000 0,07884564 0,14671923 ! T cell proliferation GO:0042098 20 11 0,000 0,07884564 0,14660062 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,07884564 0,1464822 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,07884564 0,14636397 ! bone resorption GO:0045453 16 11 0,000 0,07884564 0,14624594 ! regulated secretory pathway GO:0045055 14 11 0,000 0,07884564 0,14612809 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,07884564 0,14601044 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,07884564 0,14589297 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,07884564 0,14577569 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,07884564 0,14565861 ! syncytium formation GO:0006949 15 11 0,000 0,07884564 0,14554171 ! plasma membrane organization GO:0007009 18 11 0,000 0,07884564 0,14542499 ! focal adhesion formation GO:0048041 24 11 0,000 0,07884564 0,14530847 ! mitotic spindle organization GO:0007052 15 11 0,000 0,07884564 0,14519213 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,07884564 0,14507597 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,07884564 0,14496 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,07884564 0,14484422 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,07884564 0,14472862 ! adult heart development GO:0007512 11 11 0,000 0,07884564 0,14461321 ! temperature homeostasis GO:0001659 16 11 0,000 0,07884564 0,14449798 ! L-glutamate transport GO:0015813 16 11 0,000 0,07884564 0,14438293 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,07884564 0,14426807 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,07884564 0,14415339 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,07884564 0,14403889 ! stem cell development GO:0048864 29 11 0,000 0,07884564 0,14392457 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,07884564 0,14381044 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,07884564 0,14369649 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,07884564 0,14358271 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,07884564 0,14346912 ! vasoconstriction GO:0042310 15 11 0,000 0,07884564 0,1433557 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,07884564 0,14324247 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,07884564 0,14312941 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,07884564 0,14301653 ! ribosome assembly GO:0042255 13 11 0,000 0,07884564 0,14290383 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,07884564 0,14279131 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,07884564 0,14267896 ! chromatin silencing GO:0006342 19 11 0,000 0,07884564 0,1425668 ! nucleosome positioning GO:0016584 13 11 0,000 0,07884564 0,1424548 ! T cell homeostasis GO:0043029 20 11 0,000 0,07884564 0,14234299 ! regulation of isotype switching GO:0045191 19 11 0,000 0,07884564 0,14223134 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,07884564 0,14211988 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,07884564 0,14200859 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,07884564 0,14189747 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,07884564 0,14178652 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,07884564 0,14167575 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,07884564 0,14156516 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,07884564 0,14145473 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,07884564 0,14134448 ! male genitalia development GO:0030539 13 11 0,000 0,07884564 0,1412344 ! cholesterol efflux GO:0033344 19 11 0,000 0,07884564 0,14112449 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,07884564 0,14101475 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,07884564 0,14090518 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,07884564 0,14079578 ! germ cell migration GO:0008354 18 11 0,000 0,07884564 0,14068655 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,07884564 0,14057749 ! defense response to fungus GO:0050832 12 11 0,000 0,07884564 0,1404686 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,07884564 0,14035988 ! lysogeny GO:0030069 18 11 0,000 0,07884564 0,14025133 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,07884564 0,14014294 ! acrosome reaction GO:0007340 13 11 0,000 0,07884564 0,14003472 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,07884564 0,13992667 ! cAMP-mediated signaling GO:0019933 97 63 1,000 0,0799303 0,14174225 ! regulation of lipase activity GO:0060191 109 63 1,000 0,0799303 0,14163305 ! reproductive structure development GO:0048608 90 65 1,000 0,084329 0,14931231 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 0,084329 0,14919745 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 0,084329 0,14908278 ! lactation GO:0007595 20 12 0,000 0,08569986 0,15138991 ! reproductive cellular process GO:0048610 14 12 0,000 0,08569986 0,15127373 ! tRNA modification GO:0006400 14 12 0,000 0,08569986 0,15115772 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,08569986 0,15104189 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,08569986 0,15092624 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,08569986 0,15081076 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,08569986 0,15069547 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,08569986 0,15058034 ! non-recombinational repair GO:0000726 19 12 0,000 0,08569986 0,1504654 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,08569986 0,15035062 ! peroxisomal transport GO:0043574 21 12 0,000 0,08569986 0,15023603 ! cartilage condensation GO:0001502 18 12 0,000 0,08569986 0,15012161 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,08569986 0,15000736 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,08569986 0,14989328 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,08569986 0,14977938 ! heart looping GO:0001947 15 12 0,000 0,08569986 0,14966566 ! palate development GO:0060021 15 12 0,000 0,08569986 0,1495521 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,08569986 0,14943872 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,08569986 0,14932551 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,08569986 0,14921247 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,08569986 0,1490996 ! arginine metabolic process GO:0006525 13 12 0,000 0,08569986 0,1489869 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,08569986 0,14887437 ! methionine metabolic process GO:0006555 13 12 0,000 0,08569986 0,14876201 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,08569986 0,14864983 ! Golgi organization GO:0007030 18 12 0,000 0,08569986 0,14853781 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,08569986 0,14842596 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,08569986 0,14831427 ! monoamine transport GO:0015844 13 12 0,000 0,08569986 0,14820276 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,08569986 0,14809141 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,08569986 0,14798023 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,08569986 0,14786922 ! L-amino acid transport GO:0015807 20 12 0,000 0,08569986 0,14775837 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,08569986 0,14764769 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,08569986 0,14753718 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,08569986 0,14742683 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,08569986 0,14731664 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,08569986 0,14720662 ! cerebellum development GO:0021549 13 12 0,000 0,08569986 0,14709677 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,08569986 0,14698708 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,08569986 0,14687755 ! autonomic nervous system development GO:0048483 23 12 0,000 0,08569986 0,14676818 ! gland morphogenesis GO:0022612 23 12 0,000 0,08569986 0,14665898 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,08569986 0,14654994 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,08569986 0,14644106 ! response to gamma radiation GO:0010332 20 12 0,000 0,08569986 0,14633235 ! regulation of epidermis development GO:0045682 17 12 0,000 0,08569986 0,14622379 ! intestinal absorption GO:0050892 19 12 0,000 0,08569986 0,1461154 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,08569986 0,14600716 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,08569986 0,14589909 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,08569986 0,14579118 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,08569986 0,14568342 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,08569986 0,14557583 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,08569986 0,14546839 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,08569986 0,14536111 ! microspike assembly GO:0030035 23 12 0,000 0,08569986 0,14525399 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,08569986 0,14514703 ! response to cold GO:0009409 14 12 0,000 0,08569986 0,14504023 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,08655557 0,14638075 ! axon guidance GO:0007411 99 66 1,000 0,08655557 0,14627319 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 0,08655557 0,1461658 ! development of primary sexual characteristics GO:0045137 92 68 1,000 0,09106126 0,15366171 ! regulation of Ras GTPase activity GO:0032318 110 68 1,000 0,09106126 0,15354905 ! inorganic anion transport GO:0015698 93 68 1,000 0,09106126 0,15343656 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,09250346 0,15575254 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,09250346 0,1556386 ! cGMP metabolic process GO:0046068 16 13 0,000 0,09250346 0,15552483 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,09250346 0,15541122 ! water transport GO:0006833 17 13 0,000 0,09250346 0,15529779 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,09250346 0,15518451 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,09250346 0,1550714 ! lipid localization GO:0010876 24 13 0,000 0,09250346 0,15495846 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,09250346 0,15484568 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,09250346 0,15473307 ! organelle fusion GO:0048284 28 13 0,000 0,09250346 0,15462061 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,09250346 0,15450833 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,09250346 0,1543962 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,09250346 0,15428424 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,09250346 0,15417244 ! response to hexose stimulus GO:0009746 19 13 0,000 0,09250346 0,1540608 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,09250346 0,15394932 ! glutamate metabolic process GO:0006536 18 13 0,000 0,09250346 0,15383801 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,09250346 0,15372685 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,09250346 0,15361586 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,09250346 0,15350503 ! NAD metabolic process GO:0019674 21 13 0,000 0,09250346 0,15339435 ! exocrine system development GO:0035272 27 13 0,000 0,09250346 0,15328384 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,09250346 0,15317348 ! bone mineralization GO:0030282 15 13 0,000 0,09250346 0,15306328 ! regulation of exocytosis GO:0017157 17 13 0,000 0,09250346 0,15295325 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,09250346 0,15284337 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,09250346 0,15273364 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,09250346 0,15262408 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,09250346 0,15251467 ! genitalia development GO:0048806 15 13 0,000 0,09250346 0,15240542 ! regulation of cellular pH GO:0030641 20 13 0,000 0,09250346 0,15229632 ! cellular pigmentation GO:0033059 24 13 0,000 0,09250346 0,15218739 ! tissue regeneration GO:0042246 21 13 0,000 0,09250346 0,1520786 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,09250346 0,15196998 ! cofactor transport GO:0051181 19 13 0,000 0,09250346 0,1518615 ! NADP metabolic process GO:0006739 18 13 0,000 0,09250346 0,15175319 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,09250346 0,15164502 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,09250346 0,15153701 ! gas transport GO:0015669 18 13 0,000 0,09250346 0,15142916 ! regulation of RNA stability GO:0043487 28 13 0,000 0,09250346 0,15132146 ! heme biosynthetic process GO:0006783 20 13 0,000 0,09250346 0,15121391 ! regulation of axon extension GO:0030516 23 13 0,000 0,09250346 0,15110651 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,09250346 0,15099927 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,09250346 0,15089217 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,09250346 0,15078523 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,09250346 0,15067845 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,09250346 0,15057181 ! positive regulation of ligase activity GO:0051351 99 69 1,000 0,09333962 0,15182541 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 1,000 0,09563449 0,15544828 ! eye development GO:0001654 111 70 1,000 0,09563449 0,1553385 ! regulation of catabolic process GO:0009894 106 70 1,000 0,09563449 0,15522888 ! muscle cell differentiation GO:0042692 104 71 1,000 0,0979455 0,15886788 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,09925683 0,1608814 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,09925683 0,1607681 ! superoxide anion generation GO:0042554 18 14 0,000 0,09925683 0,16065497 ! neuron maturation GO:0042551 21 14 0,000 0,09925683 0,16054199 ! regulation of S phase GO:0033261 18 14 0,000 0,09925683 0,16042917 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,09925683 0,16031651 ! myotube differentiation GO:0014902 21 14 0,000 0,09925683 0,16020401 ! negative regulation of bone remodeling GO:0046851 26 14 0,000 0,09925683 0,16009166 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,09925683 0,15997947 ! inositol metabolic process GO:0006020 20 14 0,000 0,09925683 0,15986744 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,09925683 0,15975557 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,09925683 0,15964385 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,09925683 0,15953229 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,09925683 0,15942089 ! gene silencing by RNA GO:0031047 20 14 0,000 0,09925683 0,15930964 ! response to cAMP GO:0051591 19 14 0,000 0,09925683 0,15919854 ! limbic system development GO:0021761 25 14 0,000 0,09925683 0,1590876 ! startle response GO:0001964 21 14 0,000 0,09925683 0,15897682 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,09925683 0,15886618 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,09925683 0,15875571 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,09925683 0,15864538 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,09925683 0,15853521 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,09925683 0,1584252 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,09925683 0,15831533 ! glycine metabolic process GO:0006544 22 14 0,000 0,09925683 0,15820562 ! pituitary gland development GO:0021983 23 14 0,000 0,09925683 0,15809606 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,09925683 0,15798665 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,09925683 0,15787739 ! regulation of heart rate GO:0002027 23 14 0,000 0,09925683 0,15776828 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,09925683 0,15765933 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,09925683 0,15755052 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,09925683 0,15744187 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,09925683 0,15733336 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,09925683 0,15722501 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,09925683 0,1571168 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,09925683 0,15700874 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,09925683 0,15690083 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,09925683 0,15679307 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,09925683 0,15668545 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,09925683 0,15657799 ! mRNA splice site selection GO:0006376 26 14 0,000 0,09925683 0,15647067 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,09925683 0,1563635 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,09925683 0,15625647 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,09925683 0,15614959 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,09925683 0,15604286 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,09925683 0,15593628 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,09925683 0,15582983 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,09925683 0,15572354 ! muscle maintenance GO:0046716 19 14 0,000 0,09925683 0,15561739 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,09925683 0,15551138 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,09925683 0,15540552 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,09925683 0,1552998 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,09925683 0,15519423 ! cell killing GO:0001906 20 14 0,000 0,09925683 0,1550888 ! cilium assembly GO:0042384 20 14 0,000 0,09925683 0,15498351 ! peptide hormone secretion GO:0030072 23 14 0,000 0,09925683 0,15487836 ! response to hypoxia GO:0001666 132 72 1,000 0,10027229 0,1563568 ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,10027229 0,15625087 ! regulation of synaptic transmission GO:0050804 109 72 1,000 0,10027229 0,15614508 ! response to oxygen levels GO:0070482 137 74 1,000 0,1049718 0,1633526 ! cellular response to hormone stimulus GO:0032870 109 74 1,000 0,1049718 0,16324215 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,1049718 0,16313185 ! positive regulation of cell size GO:0045793 20 15 0,000 0,10596032 0,16455688 ! metencephalon development GO:0022037 19 15 0,000 0,10596032 0,16444584 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,10596032 0,16433496 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,10596032 0,16422422 ! skin development GO:0043588 25 15 0,000 0,10596032 0,16411363 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,10596032 0,16400319 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,10596032 0,1638929 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,10596032 0,16378276 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,10596032 0,16367276 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,10596032 0,16356291 ! bile acid metabolic process GO:0008206 22 15 0,000 0,10596032 0,16345321 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,10596032 0,16334366 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,10596032 0,16323425 ! adult walking behavior GO:0007628 25 15 0,000 0,10596032 0,16312499 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,10596032 0,16301588 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,10596032 0,16290691 ! myoblast differentiation GO:0045445 27 15 0,000 0,10596032 0,16279809 ! centrosome cycle GO:0007098 16 15 0,000 0,10596032 0,16268941 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,10596032 0,16258088 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,10596032 0,16247249 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,10596032 0,16236425 ! cerebral cortex development GO:0021987 29 15 0,000 0,10596032 0,16225615 ! response to osmotic stress GO:0006970 22 15 0,000 0,10596032 0,1621482 ! vesicle coating GO:0006901 25 15 0,000 0,10596032 0,16204039 ! DNA integration GO:0015074 22 15 0,000 0,10596032 0,16193272 ! peptide secretion GO:0002790 27 15 0,000 0,10596032 0,16182519 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,10596032 0,16171781 ! regulation of vasodilation GO:0042312 24 15 0,000 0,10596032 0,16161057 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,10596032 0,16150347 ! neuron recognition GO:0008038 22 15 0,000 0,10596032 0,16139652 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,10596032 0,1612897 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,10596032 0,16118303 ! negative regulation of tissue remodeling GO:0034104 27 15 0,000 0,10596032 0,1610765 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,10596032 0,16097011 ! biomineral formation GO:0031214 18 15 0,000 0,10596032 0,16086386 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,10596032 0,16075774 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,10596032 0,16065177 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,10596032 0,16054594 ! dopamine metabolic process GO:0042417 30 15 0,000 0,10596032 0,16044025 ! organic cation transport GO:0015695 19 15 0,000 0,10596032 0,1603347 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,10596032 0,16022928 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,10596032 0,16012401 ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,10596032 0,16001887 ! defense response to virus GO:0051607 27 15 0,000 0,10596032 0,15991387 ! peptide hormone processing GO:0016486 19 15 0,000 0,10596032 0,15980901 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,10596032 0,15970429 ! response to nutrient GO:0007584 104 75 1,000 0,10734381 0,16168354 ! response to unfolded protein GO:0006986 99 76 1,000 0,1097302 0,1651698 ! regulation of adenylate cyclase activity GO:0045761 131 77 1,000 0,11213062 0,16867261 ! cholesterol metabolic process GO:0008203 109 77 1,000 0,11213062 0,16856237 ! gland development GO:0048732 148 77 1,000 0,11213062 0,16845227 ! one-carbon metabolic process GO:0006730 110 77 1,000 0,11213062 0,16834231 ! regulation of transmission of nerve impulse GO:0051969 116 77 1,000 0,11213062 0,1682325 ! protein secretion GO:0009306 27 16 0,000 0,11261431 0,16884805 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,11261431 0,16873805 ! hormone secretion GO:0046879 25 16 0,000 0,11261431 0,16862819 ! bone remodeling GO:0046849 24 16 0,000 0,11261431 0,16851848 ! endothelial cell migration GO:0043542 22 16 0,000 0,11261431 0,16840891 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,11261431 0,16829948 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,11261431 0,1681902 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,11261431 0,16808106 ! glial cell development GO:0021782 24 16 0,000 0,11261431 0,16797205 ! patterning of blood vessels GO:0001569 24 16 0,000 0,11261431 0,16786319 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,11261431 0,16775447 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,11261431 0,16764589 ! protein polyubiquitination GO:0000209 26 16 0,000 0,11261431 0,16753746 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,11261431 0,16742916 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,11261431 0,167321 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,11261431 0,16721298 ! fructose metabolic process GO:0006000 20 16 0,000 0,11261431 0,1671051 ! regulation of protein binding GO:0043393 27 16 0,000 0,11261431 0,16699736 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,11261431 0,16688976 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,11261431 0,1667823 ! protein export from nucleus GO:0006611 24 16 0,000 0,11261431 0,16667497 ! negative regulation of immune response GO:0050777 28 16 0,000 0,11261431 0,16656779 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,11261431 0,16646074 ! DNA replication initiation GO:0006270 25 16 0,000 0,11261431 0,16635383 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,11261431 0,16624705 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,11261431 0,16614041 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,11261431 0,16603391 ! diencephalon development GO:0021536 25 16 0,000 0,11261431 0,16592755 ! oogenesis GO:0048477 23 16 0,000 0,11261431 0,16582132 ! neural crest cell migration GO:0001755 24 16 0,000 0,11261431 0,16571523 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,11261431 0,16560928 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,11261431 0,16550345 ! steroid catabolic process GO:0006706 22 16 0,000 0,11261431 0,16539777 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,11261431 0,16529222 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,11261431 0,1651868 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,11261431 0,16508152 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,11261431 0,16497637 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,11261431 0,16487136 ! sperm-egg recognition GO:0035036 16 16 0,000 0,11261431 0,16476648 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,11261431 0,16466173 ! nerve development GO:0021675 18 16 0,000 0,11261431 0,16455712 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,11261431 0,16445264 ! negative regulation of translation GO:0017148 22 16 0,000 0,11261431 0,16434829 ! regulation of cyclase activity GO:0031279 132 78 1,000 0,11454474 0,16705954 ! regulation of cAMP biosynthetic process GO:0030817 136 79 1,000 0,11697223 0,17049184 ! regulation of lyase activity GO:0051339 133 79 1,000 0,11697223 0,17038386 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,11921915 0,17354686 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,11921915 0,17343709 ! negative regulation of defense response GO:0031348 19 17 0,000 0,11921915 0,17332746 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,11921915 0,17321797 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,11921915 0,17310861 ! glycerol metabolic process GO:0006071 20 17 0,000 0,11921915 0,17299939 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,11921915 0,17289031 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,11921915 0,17278137 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,11921915 0,17267257 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,11921915 0,1725639 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,11921915 0,17245537 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,11921915 0,17234698 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,11921915 0,17223872 ! memory GO:0007613 25 17 0,000 0,11921915 0,1721306 ! keratinization GO:0031424 17 17 0,000 0,11921915 0,17202261 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,11921915 0,17191476 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,11921915 0,17180704 ! retinoid metabolic process GO:0001523 22 17 0,000 0,11921915 0,17169946 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,11921915 0,17159201 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,11921915 0,1714847 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,11921915 0,17137752 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,11921915 0,17127048 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,11921915 0,17116357 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,11921915 0,17105679 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,11921915 0,17095015 ! membrane budding GO:0006900 29 17 0,000 0,11921915 0,17084364 ! heme metabolic process GO:0042168 27 17 0,000 0,11921915 0,17073726 ! actin filament bundle formation GO:0051017 26 17 0,000 0,11921915 0,17063101 ! body fluid secretion GO:0007589 27 17 0,000 0,11921915 0,1705249 ! stem cell differentiation GO:0048863 36 17 0,000 0,11921915 0,17041892 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,11921915 0,17031307 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,11921915 0,17020735 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,11921915 0,17010176 ! sensory perception of pain GO:0019233 23 17 0,000 0,11921915 0,1699963 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,11921915 0,16989098 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,11921915 0,16978578 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,11921915 0,16968072 ! synaptogenesis GO:0007416 24 17 0,000 0,11921915 0,16957578 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,11921915 0,16947098 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,11921915 0,1693663 ! cell-cell junction organization GO:0045216 25 17 0,000 0,11921915 0,16926175 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,11921915 0,16915733 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,11921915 0,16905305 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,11921915 0,16894888 ! negative regulation of homeostatic process GO:0032845 28 17 0,000 0,11921915 0,16884485 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,11921915 0,16874095 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,11921915 0,16863717 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 0,11941275 0,16880721 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 1,000 0,11941275 0,16870352 ! regulation of cAMP metabolic process GO:0030814 141 81 1,000 0,12186599 0,17206371 ! response to protein stimulus GO:0051789 111 81 1,000 0,12186599 0,17195815 ! regulation of neurological system process GO:0031644 122 81 1,000 0,12186599 0,17185272 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,12186599 0,17174742 GO:0002696|positive regulation of leukocyte activation, ! detection of stimulus GO:0051606 108 82 1,000 0,12433163 0,17511497 ! positive regulation of translation GO:0045727 28 18 0,000 0,1257752 0,17703976 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,1257752 0,17693148 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,1257752 0,17682333 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,1257752 0,17671531 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,1257752 0,17660743 ! cAMP metabolic process GO:0046058 33 18 0,000 0,1257752 0,17649967 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,1257752 0,17639205 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,1257752 0,17628456 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,1257752 0,1761772 ! axis specification GO:0009798 26 18 0,000 0,1257752 0,17606997 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,1257752 0,17596288 GO:0050886|endocrine process, ! pancreas development GO:0031016 26 18 0,000 0,1257752 0,17585591 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,1257752 0,17574907 ! glutamine metabolic process GO:0006541 23 18 0,000 0,1257752 0,17564236 ! response to retinoic acid GO:0032526 25 18 0,000 0,1257752 0,17553578 ! pigmentation during development GO:0048066 31 18 0,000 0,1257752 0,17542933 ! central nervous system neuron development GO:0021954 30 18 0,000 0,1257752 0,17532301 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,1257752 0,17521682 ! fucose metabolic process GO:0006004 26 18 0,000 0,1257752 0,17511075 ! response to fungus GO:0009620 19 18 0,000 0,1257752 0,17500482 ! peptide cross-linking GO:0018149 31 18 0,000 0,1257752 0,17489901 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,1257752 0,17479333 ! heart process GO:0003015 27 18 0,000 0,1257752 0,17468778 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,1257752 0,17458236 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,1257752 0,17447706 ! visual learning GO:0008542 35 18 0,000 0,1257752 0,17437189 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,1257752 0,17426685 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,1257752 0,17416193 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,1257752 0,17405714 ! vitamin transport GO:0051180 24 18 0,000 0,1257752 0,17395248 ! hormone transport GO:0009914 27 18 0,000 0,1257752 0,17384794 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,1257752 0,17374352 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,1257752 0,17363924 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,1257752 0,17353507 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,1257752 0,17343104 ! cell-cell recognition GO:0009988 20 18 0,000 0,1257752 0,17332712 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,1257752 0,17322333 ! gut development GO:0048565 26 18 0,000 0,1257752 0,17311967 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,1257752 0,17301613 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 1,000 0,12680934 0,17433442 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! sterol metabolic process GO:0016125 120 84 1,000 0,12929882 0,1776507 ! rRNA metabolic process GO:0016072 107 85 1,000 0,13179975 0,18097876 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 1,000 0,13179975 0,18087078 ! anterior/posterior pattern formation GO:0009952 124 85 1,000 0,13179975 0,18076293 ! regulation of membrane potential GO:0042391 128 85 1,000 0,13179975 0,1806552 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,13228283 0,18120936 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,13228283 0,1811015 ! positive regulation of ossification GO:0045778 30 19 0,000 0,13228283 0,18099376 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,13228283 0,18088615 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,13228283 0,18077868 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,13228283 0,18067133 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,13228283 0,1805641 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,13228283 0,18045701 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,13228283 0,18035004 ! regeneration GO:0031099 32 19 0,000 0,13228283 0,18024319 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,13228283 0,18013648 ! sensory perception of taste GO:0050909 23 19 0,000 0,13228283 0,18002989 ! smooth muscle contraction GO:0006939 36 19 0,000 0,13228283 0,17992343 ! peroxisome organization GO:0007031 29 19 0,000 0,13228283 0,17981709 ! digestive system process GO:0022600 30 19 0,000 0,13228283 0,17971088 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,13228283 0,17960479 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,13228283 0,17949883 ! response to vitamin A GO:0033189 26 19 0,000 0,13228283 0,17939299 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,13228283 0,17928728 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,13228283 0,17918169 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,13228283 0,17907623 ! plasma membrane fusion GO:0045026 23 19 0,000 0,13228283 0,17897089 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,13228283 0,17886567 ! cytolysis GO:0019835 20 19 0,000 0,13228283 0,17876058 ! renal system process GO:0003014 35 19 0,000 0,13228283 0,17865562 ! vasodilation GO:0042311 33 19 0,000 0,13228283 0,17855077 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,13228283 0,17844605 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,13228283 0,17834145 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,13228283 0,17823697 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,13228283 0,17813262 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,13228283 0,17802839 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,13228283 0,17792428 ! sarcomere organization GO:0045214 23 19 0,000 0,13228283 0,17782029 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,13228283 0,17771642 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,13228283 0,17761268 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,13228283 0,17750905 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,13228283 0,17740555 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,13228283 0,17730216 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,13228283 0,1771989 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 1,000 0,13431184 0,17981213 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,13874239 0,18563554 ! iron ion transport GO:0006826 37 20 0,000 0,13874239 0,18552761 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,13874239 0,18541981 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,13874239 0,18531213 GO:0006044|N-acetylglucosamine metabolic process, ! response to vitamin GO:0033273 29 20 0,000 0,13874239 0,18520458 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,13874239 0,18509715 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,13874239 0,18498985 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,13874239 0,18488267 ! spinal cord development GO:0021510 31 20 0,000 0,13874239 0,18477562 ! response to ethanol GO:0045471 37 20 0,000 0,13874239 0,18466869 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,13874239 0,18456188 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,13874239 0,1844552 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,13874239 0,18434864 ! chromosome condensation GO:0030261 31 20 0,000 0,13874239 0,1842422 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,13874239 0,18413589 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,13874239 0,1840297 ! pallium development GO:0021543 38 20 0,000 0,13874239 0,18392363 ! DNA modification GO:0006304 28 20 0,000 0,13874239 0,18381768 ! collagen fibril organization GO:0030199 45 20 0,000 0,13874239 0,18371185 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,13874239 0,18360615 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,13874239 0,18350057 ! collagen catabolic process GO:0030574 25 20 0,000 0,13874239 0,18339511 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,13874239 0,18328977 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,13874239 0,18318455 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,13874239 0,18307946 ! alditol metabolic process GO:0019400 24 20 0,000 0,13874239 0,18297448 ! actin filament-based movement GO:0030048 34 20 0,000 0,13874239 0,18286962 ! protein processing GO:0016485 114 88 1,000 0,13936828 0,18358937 ! regulation of nucleotide metabolic process GO:0006140 150 89 1,000 0,14191204 0,18683325 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,14515422 0,1909924 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,14515422 0,1908832 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,14515422 0,19077412 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,14515422 0,19066517 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,14515422 0,19055634 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,14515422 0,19044764 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,14515422 0,19033906 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,14515422 0,19023061 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,14515422 0,19012228 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,14515422 0,19001407 ! vesicle docking GO:0048278 27 21 0,000 0,14515422 0,18990598 ! phototransduction GO:0007602 25 21 0,000 0,14515422 0,18979802 ! dendrite development GO:0016358 35 21 0,000 0,14515422 0,18969018 ! visual behavior GO:0007632 39 21 0,000 0,14515422 0,18958246 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,14515422 0,18947487 ! ovarian follicle development GO:0001541 30 21 0,000 0,14515422 0,18936739 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,14515422 0,18926004 ! autophagy GO:0006914 28 21 0,000 0,14515422 0,18915281 ! cell aging GO:0007569 32 21 0,000 0,14515422 0,18904571 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,14515422 0,18893872 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,14515422 0,18883185 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,14515422 0,18872511 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,14515422 0,18861848 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,14515422 0,18851198 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,14515422 0,1884056 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,14515422 0,18829933 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,14515422 0,18819319 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,14515422 0,18808716 ! fatty acid transport GO:0015908 30 21 0,000 0,14515422 0,18798126 ! immunoglobulin production GO:0002377 33 21 0,000 0,14515422 0,18787547 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,14515422 0,18776981 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,14515422 0,18766426 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,14515422 0,18755883 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,14515422 0,18745352 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,14515422 0,18734833 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,14515422 0,18724325 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,14515422 0,18713829 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,14515422 0,18703345 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,14515422 0,18692873 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,14515422 0,18682413 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,14515422 0,18671964 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,14515422 0,18661527 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,14515422 0,18651101 ! ATP metabolic process GO:0046034 137 91 1,000 0,14702919 0,18881471 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 1,000 0,14960202 0,19201152 ! cell fate commitment GO:0045165 141 92 1,000 0,14960202 0,19190443 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,15151869 0,19425473 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,15151869 0,19414651 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,15151869 0,19403841 ! viral genome replication GO:0019079 29 22 0,000 0,15151869 0,19393043 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,15151869 0,19382257 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,15151869 0,19371484 ! leukocyte adhesion GO:0007159 38 22 0,000 0,15151869 0,19360722 ! molting cycle process GO:0022404 40 22 0,000 0,15151869 0,19349972 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,15151869 0,19339234 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,15151869 0,19328507 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,15151869 0,19317793 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,15151869 0,19307091 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,15151869 0,192964 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,15151869 0,19285722 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,15151869 0,19275055 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,15151869 0,192644 ! lysosome organization GO:0007040 37 22 0,000 0,15151869 0,19253756 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,15151869 0,19243125 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,15151869 0,19232505 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,15151869 0,19221897 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,15151869 0,192113 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,15151869 0,19200716 ! membrane depolarization GO:0051899 35 22 0,000 0,15151869 0,19190143 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,15151869 0,19179581 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,15151869 0,19169031 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,15151869 0,19158493 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,15151869 0,19147966 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,15151869 0,19137451 ! blastocyst development GO:0001824 37 22 0,000 0,15151869 0,19126948 ! neural tube closure GO:0001843 33 22 0,000 0,15151869 0,19116456 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,15151869 0,19105975 ! protein tetramerization GO:0051262 39 22 0,000 0,15151869 0,19095506 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,15218397 0,19168846 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,15218397 0,19158355 ! response to oxidative stress GO:0006979 141 94 1,000 0,15477478 0,19473851 ! angiogenesis GO:0001525 149 95 1,000 0,15737417 0,19790081 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,15783613 0,19837328 ! neuron fate commitment GO:0048663 32 23 0,000 0,15783613 0,19826494 ! embryonic pattern specification GO:0009880 31 23 0,000 0,15783613 0,19815672 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,15783613 0,19804861 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,15783613 0,19794063 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,15783613 0,19783276 ! vesicle targeting GO:0006903 32 23 0,000 0,15783613 0,19772501 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,15783613 0,19761737 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 0,000 0,15783613 0,19750985 ! osteoblast differentiation GO:0001649 40 23 0,000 0,15783613 0,19740245 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,15783613 0,19729517 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,15783613 0,197188 ! interaction with host GO:0051701 37 23 0,000 0,15783613 0,19708095 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,15783613 0,19697402 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,15783613 0,1968672 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,15783613 0,19676049 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,15783613 0,19665391 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,15783613 0,19654743 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,15783613 0,19644108 ! cell fate determination GO:0001709 45 23 0,000 0,15783613 0,19633484 ! pentose metabolic process GO:0019321 31 23 0,000 0,15783613 0,19622871 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,15783613 0,1961227 ! spermatid development GO:0007286 33 23 0,000 0,15783613 0,1960168 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,15783613 0,19591101 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,15783613 0,19580535 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,15783613 0,19569979 ! telomere organization GO:0032200 32 23 0,000 0,15783613 0,19559435 GO:0000723|telomere maintenance, ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,15783613 0,19548902 ! regulation of amine transport GO:0051952 38 23 0,000 0,15783613 0,19538381 ! liver development GO:0001889 40 23 0,000 0,15783613 0,1952787 ! protein maturation GO:0051604 129 96 1,000 0,15998187 0,19782704 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 1,000 0,16259762 0,20095353 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,1641069 0,20270992 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,1641069 0,20260111 ! initiation of viral infection GO:0019059 42 24 0,000 0,1641069 0,20249242 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,1641069 0,20238385 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,1641069 0,20227539 ! superoxide metabolic process GO:0006801 32 24 0,000 0,1641069 0,20216704 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,1641069 0,20205882 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,1641069 0,20195071 ! fat cell differentiation GO:0045444 37 24 0,000 0,1641069 0,20184271 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,1641069 0,20173483 ! sperm motility GO:0030317 27 24 0,000 0,1641069 0,20162707 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,1641069 0,20151942 ! vacuole organization GO:0007033 39 24 0,000 0,1641069 0,20141188 ! neural crest cell development GO:0014032 39 24 0,000 0,1641069 0,20130446 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,1641069 0,20119716 ! primary neural tube formation GO:0014020 35 24 0,000 0,1641069 0,20108997 ! negative regulation of cell development GO:0010721 56 24 0,000 0,1641069 0,20098289 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,1641069 0,20087593 ! base-excision repair GO:0006284 31 24 0,000 0,1641069 0,20076908 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,1641069 0,20066235 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glutathione metabolic process GO:0006749 29 24 0,000 0,1641069 0,20055572 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,1641069 0,20044921 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,1641069 0,20034282 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,1641069 0,20023654 ! extracellular structure organization GO:0043062 156 99 1,000 0,16785222 0,20469783 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,17033133 0,20761106 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,17033133 0,20750109 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,17033133 0,20739124 ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,17033133 0,20728151 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,17033133 0,2071719 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,17033133 0,2070624 ! peptide transport GO:0015833 43 25 0,000 0,17033133 0,20695302 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,17033133 0,20684375 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,17033133 0,2067346 ! phospholipid transport GO:0015914 35 25 0,000 0,17033133 0,20662556 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,17033133 0,20651664 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,17033133 0,20640783 ! detection of light stimulus GO:0009583 30 25 0,000 0,17033133 0,20629914 ! peptidyl-tyrosine modification GO:0018212 37 25 0,000 0,17033133 0,20619056 ! leukocyte proliferation GO:0070661 39 25 0,000 0,17033133 0,20608209 GO:0032943|mononuclear cell proliferation, ! regulation of translation GO:0006417 151 100 1,000 0,17049056 0,2061663 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,17049056 0,20605796 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 1,000 0,17049056 0,20594974 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 1,000 0,17049056 0,20584163 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,17049056 0,20573363 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,17650977 0,2128854 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,17650977 0,21277383 ! translational initiation GO:0006413 43 26 0,000 0,17650977 0,21266237 ! regulation of pH GO:0006885 36 26 0,000 0,17650977 0,21255103 ! circadian rhythm GO:0007623 42 26 0,000 0,17650977 0,2124398 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,17650977 0,21232869 ! post-embryonic development GO:0009791 42 26 0,000 0,17650977 0,2122177 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,17650977 0,21210682 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,17650977 0,21199606 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,17650977 0,21188542 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,17650977 0,21177489 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,17650977 0,21166447 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,17650977 0,21155417 ! regulation of coagulation GO:0050818 39 26 0,000 0,17650977 0,21144399 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,18264254 0,21867665 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,18264254 0,21856287 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,18264254 0,21844922 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,18264254 0,21833568 ! membrane docking GO:0022406 39 27 0,000 0,18264254 0,21822226 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,18264254 0,21810895 ! catechol metabolic process GO:0009712 43 27 0,000 0,18264254 0,21799577 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,18264254 0,2178827 ! acute-phase response GO:0006953 42 27 0,000 0,18264254 0,21776975 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,18264254 0,21765691 ! myofibril assembly GO:0030239 36 27 0,000 0,18264254 0,2175442 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,18264254 0,2174316 ! response to ionizing radiation GO:0010212 47 27 0,000 0,18264254 0,21731911 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,18264254 0,21720674 ! natural killer cell activation GO:0030101 35 27 0,000 0,18264254 0,21709449 ! lipid oxidation GO:0034440 38 27 0,000 0,18264254 0,21698236 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,18264254 0,21687034 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,18264254 0,21675843 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,18264254 0,21664664 ! gene silencing GO:0016458 41 27 0,000 0,18264254 0,21653497 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,18872999 0,22363678 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,18872999 0,22352162 ! phenol metabolic process GO:0018958 44 28 0,000 0,18872999 0,22340658 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,18872999 0,22329166 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,18872999 0,22317685 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,18872999 0,22306217 ! cell junction assembly GO:0034329 56 28 0,000 0,18872999 0,2229476 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,18872999 0,22283315 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,18872999 0,22271882 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,18872999 0,22260461 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,18872999 0,22249051 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,18872999 0,22237653 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,18872999 0,22226266 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,18872999 0,22214892 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,18872999 0,22203529 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,18872999 0,22192177 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,18872999 0,22180837 ! mesoderm formation GO:0001707 46 28 0,000 0,18872999 0,22169509 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,18872999 0,22158192 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,18872999 0,22146887 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,18872999 0,22135593 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,18872999 0,22124311 ! neural tube formation GO:0001841 41 28 0,000 0,18872999 0,2211304 ! positive regulation of catabolic process GO:0009896 40 28 0,000 0,18872999 0,22101781 ! placenta development GO:0001890 37 28 0,000 0,18872999 0,22090533 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,19477245 0,22786197 ! regulation of innate immune response GO:0045088 38 29 0,000 0,19477245 0,22774613 ! ovulation cycle process GO:0022602 41 29 0,000 0,19477245 0,22763041 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,19477245 0,2275148 ! protein targeting to membrane GO:0006612 53 29 0,000 0,19477245 0,22739931 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,19477245 0,22728394 ! mismatch repair GO:0006298 34 29 0,000 0,19477245 0,22716868 ! muscle cell development GO:0055001 38 29 0,000 0,19477245 0,22705354 ! formation of primary germ layer GO:0001704 48 29 0,000 0,19477245 0,22693852 ! telencephalon development GO:0021537 52 29 0,000 0,19477245 0,22682362 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,19477245 0,22670883 ! eye morphogenesis GO:0048592 51 29 0,000 0,19477245 0,22659415 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,19477245 0,2264796 ! tissue homeostasis GO:0001894 42 29 0,000 0,19477245 0,22636515 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,20077025 0,23321797 ! collagen metabolic process GO:0032963 40 30 0,000 0,20077025 0,23310024 ! organic anion transport GO:0015711 51 30 0,000 0,20077025 0,23298263 ! cholesterol transport GO:0030301 46 30 0,000 0,20077025 0,23286514 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,20077025 0,23274777 ! spliceosome assembly GO:0000245 49 30 0,000 0,20077025 0,23263052 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,20077025 0,23251338 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,20077025 0,23239637 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,20077025 0,23227947 ! ceramide metabolic process GO:0006672 43 30 0,000 0,20077025 0,23216268 ! ovulation cycle GO:0042698 43 30 0,000 0,20077025 0,23204602 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,20077025 0,23192947 ! adult locomotory behavior GO:0008344 47 30 0,000 0,20077025 0,23181304 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,20077025 0,23169673 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,20077025 0,23158053 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,20077025 0,23146445 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,20672372 0,23820869 ! negative regulation of secretion GO:0051048 49 31 0,000 0,20672372 0,23808941 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,20672372 0,23797024 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,20672372 0,2378512 ! odontogenesis GO:0042476 50 31 0,000 0,20672372 0,23773227 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,20672372 0,23761347 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,20672372 0,23749478 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,20672372 0,23737621 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,20672372 0,23725776 ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,20672372 0,23713943 ! RNA modification GO:0009451 40 31 0,000 0,20672372 0,23702121 ! regulation of muscle development GO:0048634 48 32 0,000 0,21263317 0,24367528 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,21263317 0,24355393 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,21263317 0,2434327 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,21263317 0,24331159 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,21263317 0,2431906 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,21263317 0,24306973 ! cytokine production GO:0001816 44 32 0,000 0,21263317 0,24294898 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,21263317 0,24282835 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,21263317 0,24270784 ! vesicle localization GO:0051648 47 32 0,000 0,21263317 0,24258745 ! RNA export from nucleus GO:0006405 44 33 0,000 0,21849894 0,24915596 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,21849894 0,24903249 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,21849894 0,24890915 ! actomyosin structure organization GO:0031032 43 33 0,000 0,21849894 0,24878592 ! cell junction organization GO:0034330 63 33 0,000 0,21849894 0,24866282 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,21849894 0,24853985 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,21849894 0,24841699 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,21849894 0,24829425 GO:0042593|glucose homeostasis, ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,21849894 0,24817164 ! female gonad development GO:0008585 49 33 0,000 0,21849894 0,24804914 ! positive regulation of cell development GO:0010720 54 33 0,000 0,21849894 0,24792677 ! lipid homeostasis GO:0055088 55 33 0,000 0,21849894 0,24780452 ! regulation of proteolysis GO:0030162 50 33 0,000 0,21849894 0,24768239 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,21849894 0,24756038 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,21849894 0,24743849 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,21849894 0,24731672 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,22432135 0,25378214 ! mRNA catabolic process GO:0006402 48 34 0,000 0,22432135 0,25365737 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,22432135 0,25353273 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,22432135 0,2534082 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,22432135 0,2532838 ! feeding behavior GO:0007631 45 34 0,000 0,22432135 0,25315952 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,22432135 0,25303536 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,22432135 0,25291132 ! neuron migration GO:0001764 46 34 0,000 0,22432135 0,25278741 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,22432135 0,25266361 ! female gamete generation GO:0007292 43 34 0,000 0,22432135 0,25253994 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,22432135 0,25241639 ! polyol metabolic process GO:0019751 44 34 0,000 0,22432135 0,25229296 ! aerobic respiration GO:0009060 47 34 0,000 0,22432135 0,25216965 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,22432135 0,25204646 ! embryonic organ development GO:0048568 45 34 0,000 0,22432135 0,25192339 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,22432135 0,25180044 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,2301007 0,25816177 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,2301007 0,25803589 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,2301007 0,25791015 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,2301007 0,25778452 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,2301007 0,25765902 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,2301007 0,25753363 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 51 35 0,000 0,2301007 0,25740838 ! pigment metabolic process GO:0042440 61 35 0,000 0,2301007 0,25728324 ! protein homooligomerization GO:0051260 52 35 0,000 0,2301007 0,25715822 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,23583733 0,26344141 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,23583733 0,26331352 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,23583733 0,26318576 ! organic ether metabolic process GO:0018904 46 36 0,000 0,23583733 0,26305813 ! tissue remodeling GO:0048771 62 36 0,000 0,23583733 0,26293062 ! neural tube development GO:0021915 50 36 0,000 0,23583733 0,26280323 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,23583733 0,26267596 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,23583733 0,26254882 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,23583733 0,2624218 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,23583733 0,2622949 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,24153154 0,26849808 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,24153154 0,26836838 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,24153154 0,26823879 ! ion transmembrane transport GO:0034220 56 37 0,000 0,24153154 0,26810933 ! regulation of protein secretion GO:0050708 51 37 0,000 0,24153154 0,26798 ! amino acid activation GO:0043038 52 37 0,000 0,24153154 0,26785079 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,24153154 0,2677217 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,24718364 0,27385471 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,24718364 0,27372285 ! phagocytosis GO:0006909 60 38 0,000 0,24718364 0,27359113 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,25279394 0,27966622 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,25279394 0,27953176 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,25279394 0,27939744 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,25279394 0,27926324 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,25279394 0,27912917 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,25279394 0,27899523 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,25279394 0,27886142 ! JNK cascade GO:0007254 54 39 0,000 0,25279394 0,27872774 ! developmental growth GO:0048589 62 39 0,000 0,25279394 0,27859419 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,25836275 0,28459499 ! response to calcium ion GO:0051592 58 40 0,000 0,25836275 0,28445875 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,25836275 0,28432265 ! regulation of tube size GO:0035150 60 40 0,000 0,25836275 0,28418667 GO:0050880|regulation of blood vessel size, ! peptide metabolic process GO:0006518 56 40 0,000 0,25836275 0,28405083 ! double-strand break repair GO:0006302 67 40 0,000 0,25836275 0,28391511 ! B cell differentiation GO:0030183 62 40 0,000 0,25836275 0,28377953 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,25836275 0,28364407 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,26389038 0,28957437 ! glucose transport GO:0015758 52 41 0,000 0,26389038 0,28943628 ! striated muscle contraction GO:0006941 62 41 0,000 0,26389038 0,28929832 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,26389038 0,28916049 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,26389038 0,2890228 ! mitochondrial transport GO:0006839 60 42 0,000 0,26937712 0,29489166 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,26937712 0,29475137 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,26937712 0,29461121 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,26937712 0,29447119 ! hexose transport GO:0008645 54 42 0,000 0,26937712 0,29433129 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,26937712 0,29419154 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,26937712 0,29405191 ! excretion GO:0007588 63 42 0,000 0,26937712 0,29391242 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,26937712 0,29377306 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,26937712 0,29363383 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,26937712 0,29349473 ! regulation of cell shape GO:0008360 78 42 0,000 0,26937712 0,29335577 ! regulation of gene-specific transcription GO:0032583 69 43 0,000 0,27482328 0,29914507 ! neuromuscular process GO:0050905 79 43 0,000 0,27482328 0,29900357 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,27482328 0,29886219 ! tRNA processing GO:0008033 49 43 0,000 0,27482328 0,29872095 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,27482328 0,29857985 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,27482328 0,29843887 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,28022915 0,30416566 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,28022915 0,30402219 ! glycolysis GO:0006096 53 44 0,000 0,28022915 0,30387885 ! regulation of ion transport GO:0043269 57 44 0,000 0,28022915 0,30373564 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,28022915 0,30359258 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,28022915 0,30344964 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,28022915 0,30330684 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,28022915 0,30316418 ! RNA catabolic process GO:0006401 64 45 0,000 0,28559503 0,30882396 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,28559503 0,30867884 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,28559503 0,30853385 ! cell recognition GO:0008037 58 45 0,000 0,28559503 0,308389 ! cell maturation GO:0048469 60 45 0,000 0,28559503 0,30824428 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,29092121 0,31384558 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,29092121 0,31369844 ! cell redox homeostasis GO:0045454 63 46 0,000 0,29092121 0,31355144 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,29092121 0,31340458 ! regulation of ossification GO:0030278 71 46 0,000 0,29092121 0,31325786 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,29092121 0,31311127 ! viral infectious cycle GO:0019058 71 47 0,000 0,29620799 0,31865218 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,29620799 0,31850321 ! endocrine system development GO:0035270 83 47 0,000 0,29620799 0,31835438 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,29620799 0,31820568 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,29620799 0,31805713 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,29620799 0,31790871 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,29620799 0,31776043 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,29620799 0,31761229 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,30145565 0,32308853 ! gastrulation GO:0007369 73 48 0,000 0,30145565 0,32293805 ! heart morphogenesis GO:0003007 65 48 0,000 0,30145565 0,3227877 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,30145565 0,3226375 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,30145565 0,32248744 ! regulation of endocytosis GO:0030100 63 48 0,000 0,30145565 0,32233751 ! nuclear export GO:0051168 69 48 0,000 0,30145565 0,32218773 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,30145565 0,32203808 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,30666448 0,32745046 ! sensory perception of smell GO:0007608 61 49 0,000 0,30666448 0,32729852 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,30666448 0,32714671 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,30666448 0,32699504 ! RNA elongation GO:0006354 62 49 0,000 0,30666448 0,32684351 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,30666448 0,32669213 ! regulation of actin filament length GO:0030832 72 50 0,000 0,31183477 0,33204628 ! membrane fusion GO:0006944 80 50 0,000 0,31183477 0,33189262 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,31183477 0,33173911 ! positive regulation of growth GO:0045927 67 50 0,000 0,31183477 0,33158574 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,31183477 0,33143251 ! proton transport GO:0015992 75 50 0,000 0,31183477 0,33127943 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,31183477 0,33112648 ! positive regulation of secretion GO:0051047 71 51 0,000 0,31696679 0,33642068 ! hydrogen transport GO:0006818 77 51 0,000 0,31696679 0,33626551 ! adult behavior GO:0030534 80 51 0,000 0,31696679 0,33611048 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,31696679 0,33595559 ! transition metal ion transport GO:0000041 74 52 0,000 0,32206084 0,34119757 ! regulation of cellular component size GO:0032535 74 52 0,000 0,32206084 0,34104048 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,32206084 0,34088354 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,32206084 0,34072674 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,32711718 0,34591702 ! regulation of bone remodeling GO:0046850 90 53 0,000 0,32711718 0,34575805 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,32711718 0,34559923 ! single fertilization GO:0007338 59 53 0,000 0,32711718 0,34544055 ! amino acid transport GO:0006865 84 54 0,000 0,3321361 0,35057964 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,3321361 0,35041882 ! glucose catabolic process GO:0006007 66 54 0,000 0,3321361 0,35025816 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,3321361 0,35009763 ! regulation of tissue remodeling GO:0034103 91 54 0,000 0,3321361 0,34993726 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,3321361 0,34977703 ! exocytosis GO:0006887 74 55 0,000 0,33711787 0,35486092 ! mesoderm development GO:0007498 76 55 0,000 0,33711787 0,35469859 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,33711787 0,3545364 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,34206277 0,35957238 ! carbohydrate transport GO:0008643 74 57 0,000 0,34697106 0,3645653 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,34697106 0,36439883 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,34697106 0,36423251 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,34697106 0,36406635 ! secondary metabolic process GO:0019748 84 57 0,000 0,34697106 0,36390033 ! viral reproductive process GO:0022415 87 58 0,000 0,35184301 0,36884181 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,35184301 0,36867377 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,35667889 0,37357079 ! activation of MAPK activity GO:0000187 84 59 0,000 0,35667889 0,37340075 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,35667889 0,37323087 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,36147897 0,37808169 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,36147897 0,37790983 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,36147897 0,37773813 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,36147897 0,37756659 ! fertilization GO:0009566 68 60 0,000 0,36147897 0,3773952 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,3662435 0,38219603 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,3662435 0,3820227 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,3662435 0,38184953 ! extracellular matrix organization GO:0030198 103 61 0,000 0,3662435 0,38167651 ! amine catabolic process GO:0009310 90 62 0,000 0,37097276 0,38642996 ! neurotransmitter transport GO:0006836 81 62 0,000 0,37097276 0,38625502 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,37097276 0,38608025 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,37097276 0,38590563 ! viral reproduction GO:0016032 92 63 0,000 0,37566699 0,39061215 ! appendage morphogenesis GO:0035107 93 64 0,000 0,38032646 0,39527829 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,38032646 0,39509976 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,38032646 0,39492138 ! hexose catabolic process GO:0019320 82 64 0,000 0,38032646 0,39474317 ! adaptive immune response GO:0002250 94 64 0,000 0,38032646 0,39456512 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! appendage development GO:0048736 94 65 0,000 0,38495142 0,39918317 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,38495142 0,39900328 ! defense response to bacterium GO:0042742 73 65 0,000 0,38495142 0,39882354 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,38495142 0,39864398 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,38495142 0,39846457 ! activation of immune response GO:0002253 83 65 0,000 0,38495142 0,39828532 ! protein oligomerization GO:0051259 100 65 0,000 0,38495142 0,39810624 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,38954213 0,40267276 ! antigen processing and presentation GO:0019882 96 66 0,000 0,38954213 0,40249186 ! regulation of immune effector process GO:0002697 101 66 0,000 0,38954213 0,40231113 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,39409883 0,40683452 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,39409883 0,406652 ! acute inflammatory response GO:0002526 92 68 0,000 0,39862178 0,41113457 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,39862178 0,41095029 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,39862178 0,41076617 ! rhythmic process GO:0048511 105 68 0,000 0,39862178 0,41058222 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,40311122 0,41502051 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,40311122 0,41483481 ! response to drug GO:0042493 108 69 0,000 0,40311122 0,41464929 ! response to metal ion GO:0010038 103 70 0,000 0,40756741 0,41904561 ! humoral immune response GO:0006959 86 70 0,000 0,40756741 0,41885837 ! amine transport GO:0015837 101 70 0,000 0,40756741 0,4186713 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,40756741 0,41848439 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,41199058 0,42283727 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,41199058 0,42264867 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,41199058 0,42246024 ! regulation of blood pressure GO:0008217 107 73 0,000 0,42073884 0,43123856 ! tube morphogenesis GO:0035239 118 73 0,000 0,42073884 0,43104647 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,42073884 0,43085456 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,42073884 0,43066281 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,42506442 0,43489687 ! digestion GO:0007586 97 74 0,000 0,42506442 0,43470349 ! protein import into nucleus GO:0006606 118 74 0,000 0,42506442 0,43451029 ! blood coagulation GO:0007596 116 75 0,000 0,42935794 0,43870425 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,42935794 0,43850944 ! nuclear import GO:0051170 121 75 0,000 0,42935794 0,43831481 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,42935794 0,43812035 ! amine biosynthetic process GO:0009309 97 76 0,000 0,43361964 0,44227281 ! tRNA metabolic process GO:0006399 95 76 0,000 0,43361964 0,44207676 ! regulation of cell morphogenesis GO:0022604 140 76 0,000 0,43361964 0,44188089 ! protein ubiquitination GO:0016567 125 77 0,000 0,43784976 0,445994 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,43784976 0,44579657 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,44204853 0,4498724 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,44621617 0,45391296 ! chromatin assembly GO:0031497 102 80 0,000 0,45035292 0,45791854 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,45035292 0,45771618 ! protein localization in nucleus GO:0034504 133 80 0,000 0,45035292 0,45751401 ! hemostasis GO:0007599 125 81 0,000 0,45445901 0,46148156 ! mRNA transport GO:0051028 121 81 0,000 0,45445901 0,4612779 ! vitamin metabolic process GO:0006766 103 81 0,000 0,45445901 0,46107443 ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,46258009 0,46910679 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,46659553 0,47297034 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,47058119 0,47680032 ! negative regulation of multicellular organismal process GO:0051241 133 85 0,000 0,47058119 0,47659037 ! nucleosome organization GO:0034728 114 87 0,000 0,47846407 0,48436064 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,47846407 0,48414754 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,47846407 0,48393464 ! female pregnancy GO:0007565 130 87 0,000 0,47846407 0,48372192 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,48236173 0,48744814 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,48236173 0,48723407 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,48236173 0,48702018 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,48236173 0,48680648 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! regulation of neurogenesis GO:0050767 153 89 0,000 0,48623047 0,49049565 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,48623047 0,49028062 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,49007053 0,49393611 ! hormone metabolic process GO:0042445 121 90 0,000 0,49007053 0,49371976 ! RNA localization GO:0006403 135 91 0,000 0,4938821 0,49734186 ! response to virus GO:0009615 122 91 0,000 0,4938821 0,49712421 ! positive regulation of immune response GO:0050778 121 92 0,000 0,49766539 0,50071321 ! DNA recombination GO:0006310 146 92 0,000 0,49766539 0,50049427 ! sulfur metabolic process GO:0006790 118 92 0,000 0,49766539 0,50027553 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,50142063 0,50383025 ! carboxylic acid transport GO:0046942 147 95 0,000 0,50884772 0,51106976 GO:0015849|organic acid transport, ! in utero embryonic development GO:0001701 147 96 0,000 0,51251999 0,51453339 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,51251999 0,51430889 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,51251999 0,5140846 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,51251999 0,5138605 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,51616502 0,51728956 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,52337413 0,52428593 ! protein import GO:0017038 156 99 0,000 0,52337413 0,52405768 ! divalent metal ion transport GO:0070838 171 100 0,000 0,52693861 0,52739721 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,52693861 0,52716781 ! protein localization in organelle GO:0033365 161 100 0,000 0,52693861 0,52693861