pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6447-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of phosphorylation GO:0042326 47 24 6,000 6,571E-11 1,581E-07 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 6,000 1,237E-10 1,488E-07 GO:0045936|negative regulation of phosphate metabolic process, ! cell cycle arrest GO:0007050 213 100 7,000 1,365E-07 1,095E-04 ! regulation of epithelial cell proliferation GO:0050678 111 43 5,000 1,863E-07 1,121E-04 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 3,000 2,303E-07 1,108E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 5,000 2,821E-07 1,131E-04 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 4,000 3,111E-07 1,069E-04 ! cellular response to extracellular stimulus GO:0031668 48 29 4,000 6,824E-07 2,052E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 5,000 1,036E-06 2,771E-04 ! interphase of mitotic cell cycle GO:0051329 209 95 6,000 1,48E-06 3,562E-04 ! interphase GO:0051325 213 98 6,000 1,826E-06 3,995E-04 ! cellular response to nutrient GO:0031670 8 5 2,000 1,945E-06 3,9E-04 ! androgen receptor signaling pathway GO:0030521 74 36 4,000 2,096E-06 3,879E-04 ! negative regulation of protein kinase activity GO:0006469 130 67 5,000 2,716E-06 4,667E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 5,000 2,716E-06 4,356E-04 ! negative regulation of kinase activity GO:0033673 131 68 5,000 2,964E-06 4,458E-04 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 3,000 4,079E-06 5,773E-04 ! negative regulation of transferase activity GO:0051348 140 72 5,000 4,15E-06 5,548E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 4,000 6,509E-06 8,243E-04 ! positive regulation of protein ubiquitination GO:0031398 12 7 2,000 6,75E-06 8,12E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 6,75E-06 7,733E-04 ! positive regulation of phosphorylation GO:0042327 129 79 5,000 7,139E-06 7,807E-04 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 5,000 8,255E-06 8,635E-04 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 1,075E-05 1,078E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,075E-05 1,035E-03 ! vasculogenesis GO:0001570 46 25 3,000 1,295E-05 1,199E-03 ! cellular response to nutrient levels GO:0031669 41 25 3,000 1,295E-05 1,154E-03 ! induction of positive chemotaxis GO:0050930 15 9 2,000 1,606E-05 1,38E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 2,000 2,284E-05 1,895E-03 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 2,284E-05 1,832E-03 ! chondrocyte differentiation GO:0002062 24 11 2,000 3,128E-05 2,427E-03 ! negative regulation of glucose import GO:0046325 17 11 2,000 3,128E-05 2,352E-03 GO:0010829|negative regulation of glucose transport, ! steroid hormone receptor signaling pathway GO:0030518 129 63 4,000 3,44E-05 2,508E-03 ! regulation of B cell proliferation GO:0030888 20 12 2,000 4,152E-05 2,938E-03 ! regulation of positive chemotaxis GO:0050926 19 12 2,000 4,152E-05 2,854E-03 GO:0050927|positive regulation of positive chemotaxis, ! negative regulation of mast cell proliferation GO:0070667 23 12 2,000 4,152E-05 2,775E-03 GO:0042130|negative regulation of T cell proliferation, ! negative regulation of cell growth GO:0030308 132 67 4,000 4,638E-05 3,016E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 4,000 4,983E-05 3,155E-03 ! negative regulation of cell size GO:0045792 134 69 4,000 5,347E-05 3,298E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 4,000 6,563E-05 3,948E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 6,811E-05 3,997E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 8,477E-05 4,856E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 8,477E-05 4,743E-03 ! regulation of protein ubiquitination GO:0031396 25 16 2,000 1,039E-04 5,681E-03 ! axon cargo transport GO:0008088 43 16 2,000 1,039E-04 5,554E-03 ! negative regulation of leukocyte proliferation GO:0070664 31 16 2,000 1,039E-04 5,434E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! DNA fragmentation involved in apoptosis GO:0006309 25 17 2,000 1,256E-04 6,43E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 1,256E-04 6,296E-03 ! negative regulation of growth GO:0045926 155 84 4,000 1,369E-04 6,72E-03 ! cell growth GO:0016049 84 45 3,000 1,393E-04 6,702E-03 ! phosphoinositide phosphorylation GO:0046854 33 18 2,000 1,501E-04 7,08E-03 ! positive regulation of protein modification process GO:0031401 136 88 4,000 1,704E-04 7,886E-03 ! lipid phosphorylation GO:0046834 35 19 2,000 1,775E-04 8,056E-03 ! regulation of mast cell proliferation GO:0070666 81 48 3,000 1,794E-04 7,994E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 2,079E-04 9,094E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 2,079E-04 8,931E-03 ! regulation of glucose import GO:0046324 29 20 2,000 2,079E-04 8,774E-03 GO:0010827|regulation of glucose transport, ! inner ear receptor cell differentiation GO:0060113 37 20 2,000 2,079E-04 8,623E-03 ! negative regulation of T cell activation GO:0050868 40 20 2,000 2,079E-04 8,477E-03 ! regulation of leukocyte proliferation GO:0070663 88 51 3,000 2,273E-04 9,115E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! inactivation of MAPK activity GO:0000188 39 21 2,000 2,415E-04 9,525E-03 ! cell structure disassembly during apoptosis GO:0006921 30 21 2,000 2,415E-04 9,371E-03 ! positive regulation of locomotion GO:0040017 39 21 2,000 2,415E-04 9,222E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 35 21 2,000 2,415E-04 9,078E-03 ! response to UV GO:0009411 104 53 3,000 2,64E-04 9,77E-03 ! microtubule-based transport GO:0010970 54 22 2,000 2,784E-04 0,01014928 ! regulation of chemotaxis GO:0050920 40 22 2,000 2,784E-04 9,998E-03 ! mechanoreceptor differentiation GO:0042490 40 22 2,000 2,784E-04 9,851E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 2,784E-04 9,708E-03 ! apoptotic nuclear changes GO:0030262 32 22 2,000 2,784E-04 9,569E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 2,784E-04 9,435E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 3,357E-04 0,01121706 ! microvillus organization GO:0032528 7 5 1,000 3,357E-04 0,0110634 GO:0030033|microvillus assembly, ! mRNA transcription GO:0009299 9 5 1,000 3,357E-04 0,01091389 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 3,357E-04 0,01076837 ! peptidyl-histidine phosphorylation GO:0018106 9 5 1,000 3,357E-04 0,01062668 ! early endosome to late endosome transport GO:0045022 12 5 1,000 3,357E-04 0,01048868 ! meiotic chromosome segregation GO:0045132 7 5 1,000 3,357E-04 0,01035421 ! negative regulation of fibrinolysis GO:0051918 11 5 1,000 3,357E-04 0,01022314 ! stem cell division GO:0017145 11 5 1,000 3,357E-04 0,01009535 GO:0048103|somatic stem cell division, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 2,000 3,628E-04 0,01077589 ! regulation of behavior GO:0050795 43 24 2,000 3,628E-04 0,01064447 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 2,000 4,105E-04 0,01189905 ! ear development GO:0043583 103 62 3,000 4,827E-04 0,01382624 ! male meiosis GO:0007140 7 6 1,000 5,016E-04 0,01419744 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 1,000 5,016E-04 0,01403235 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 1,000 5,016E-04 0,01387106 ! establishment of spindle localization GO:0051293 12 6 1,000 5,016E-04 0,01371343 GO:0051653|spindle localization, ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 5,016E-04 0,01355935 ! cytoplasmic microtubule organization GO:0031122 14 6 1,000 5,016E-04 0,01340869 ! negative regulation of B cell activation GO:0050869 13 6 1,000 5,016E-04 0,01326134 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 5,176E-04 0,01353545 ! regulation of chromosome organization GO:0033044 42 27 2,000 5,176E-04 0,01338991 ! negative regulation of lymphocyte activation GO:0051250 53 27 2,000 5,176E-04 0,01324746 ! negative regulation of protein modification process GO:0031400 60 28 2,000 5,772E-04 0,01461812 ! regulation of lipid kinase activity GO:0043550 13 7 1,000 6,995E-04 0,01753124 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 6,995E-04 0,01735051 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 6,995E-04 0,01717346 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 6,995E-04 0,01699999 ! anterograde axon cargo transport GO:0008089 18 7 1,000 6,995E-04 0,01682999 ! coenzyme A metabolic process GO:0015936 12 7 1,000 6,995E-04 0,01666336 ! peptidyl-histidine modification GO:0018202 16 7 1,000 6,995E-04 0,01649999 ! negative regulation of leukocyte activation GO:0002695 56 30 2,000 7,092E-04 0,01656667 ! regulation of B cell activation GO:0050864 50 30 2,000 7,092E-04 0,01640737 ! cell cycle checkpoint GO:0000075 137 69 3,000 7,247E-04 0,01660609 ! negative regulation of transcription regulator activity GO:0090048 58 31 2,000 7,818E-04 0,01774632 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 8,59E-04 0,01931618 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 9,291E-04 0,02069792 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 9,291E-04 0,02050803 ! ER overload response GO:0006983 12 8 1,000 9,291E-04 0,02032159 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 9,291E-04 0,02013851 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 9,291E-04 0,01995871 ! ATP catabolic process GO:0006200 11 8 1,000 9,291E-04 0,01978208 ! leukocyte chemotaxis GO:0030595 50 33 2,000 9,409E-04 0,01985784 GO:0060326|cell chemotaxis, ! regulation of transcription factor activity GO:0051090 126 74 3,000 9,43E-04 0,01972861 GO:0090046|regulation of transcription regulator activity, ! middle ear morphogenesis GO:0042474 14 9 1,000 1,19E-03 0,02468115 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 1,000 1,19E-03 0,0244702 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,19E-03 0,02426283 ! receptor clustering GO:0043113 18 9 1,000 1,19E-03 0,02405894 ! regulation of Notch signaling pathway GO:0008593 22 9 1,000 1,19E-03 0,02385845 ! motor axon guidance GO:0008045 16 9 1,000 1,19E-03 0,02366127 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 1,19E-03 0,02346732 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 1,000 1,19E-03 0,02327653 ! induction of an organ GO:0001759 14 9 1,000 1,19E-03 0,02308882 ! synaptic vesicle endocytosis GO:0048488 20 9 1,000 1,19E-03 0,02290411 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 1,19E-03 0,02272233 ! regulation of fibrinolysis GO:0051917 16 9 1,000 1,19E-03 0,02254341 ! regulation of telomere maintenance GO:0032204 14 9 1,000 1,19E-03 0,02236729 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 2,000 1,216E-03 0,02267211 ! negative regulation of cell activation GO:0050866 65 36 2,000 1,216E-03 0,02249771 ! negative regulation of DNA binding GO:0043392 68 37 2,000 1,317E-03 0,02419215 ! regulation of protein stability GO:0031647 73 37 2,000 1,317E-03 0,02400888 ! nucleus organization GO:0006997 67 38 2,000 1,424E-03 0,02576033 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,482E-03 0,02660467 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 1,000 1,482E-03 0,0264076 ! alpha-beta T cell activation GO:0046631 23 10 1,000 1,482E-03 0,02621343 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 1,000 1,482E-03 0,02602209 ! midbrain development GO:0030901 13 10 1,000 1,482E-03 0,02583352 ! localization within membrane GO:0051668 20 10 1,000 1,482E-03 0,02564767 ! negative regulation of transport GO:0051051 153 84 3,000 1,511E-03 0,02597417 ! negative regulation of binding GO:0051100 72 40 2,000 1,654E-03 0,02821562 ! mesenchymal cell development GO:0014031 87 40 2,000 1,654E-03 0,02801692 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of T cell proliferation GO:0042129 71 41 2,000 1,776E-03 0,02988933 ! T cell differentiation GO:0030217 81 41 2,000 1,776E-03 0,02968177 ! regulation of T cell differentiation GO:0045580 70 41 2,000 1,776E-03 0,02947707 ! regulation of DNA binding GO:0051101 155 88 3,000 1,794E-03 0,02956213 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,804E-03 0,02952743 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,804E-03 0,02932792 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 1,000 1,804E-03 0,02913109 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,804E-03 0,02893688 ! purine ribonucleotide catabolic process GO:0009154 17 11 1,000 1,804E-03 0,02874525 ! developmental induction GO:0031128 19 11 1,000 1,804E-03 0,02855613 GO:0045168|cell-cell signaling involved in cell fate specification, ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 2,000 1,905E-03 0,02995638 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 1,905E-03 0,02976186 ! positive regulation of response to external stimulus GO:0032103 77 43 2,000 2,039E-03 0,03165206 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 2,157E-03 0,03326063 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 2,157E-03 0,03304878 ! oligodendrocyte differentiation GO:0048709 16 12 1,000 2,157E-03 0,03283961 ! regulation of interleukin-12 production GO:0032655 19 12 1,000 2,157E-03 0,03263307 ! histone acetylation GO:0016573 26 12 1,000 2,157E-03 0,03242912 ! histone methylation GO:0016571 26 12 1,000 2,157E-03 0,03222769 ! peptidyl-lysine modification GO:0018205 21 12 1,000 2,157E-03 0,03202876 ! JAK-STAT cascade GO:0007259 71 44 2,000 2,179E-03 0,03216324 ! leukocyte migration GO:0050900 68 45 2,000 2,325E-03 0,03410454 ! ATP synthesis coupled electron transport GO:0042773 64 45 2,000 2,325E-03 0,03389784 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 2,476E-03 0,03589081 ! positive regulation of protein transport GO:0051222 72 46 2,000 2,476E-03 0,03567589 ! ribonucleotide catabolic process GO:0009261 20 13 1,000 2,539E-03 0,03636036 ! nucleoside triphosphate catabolic process GO:0009143 21 13 1,000 2,539E-03 0,03614521 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 2,539E-03 0,03593259 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 2,539E-03 0,03572246 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 2,539E-03 0,03551477 ! positive regulation of defense response GO:0031349 76 47 2,000 2,634E-03 0,03662999 ! positive regulation of cell cycle GO:0045787 89 48 2,000 2,797E-03 0,03868204 ! Notch signaling pathway GO:0007219 96 48 2,000 2,797E-03 0,038461 ! cellular component disassembly GO:0022411 86 48 2,000 2,797E-03 0,03824247 ! activation of caspase activity GO:0006919 84 48 2,000 2,797E-03 0,03802641 ! regulation of inflammatory response GO:0050727 75 48 2,000 2,797E-03 0,03781278 ! regulation of lymphocyte differentiation GO:0045619 81 48 2,000 2,797E-03 0,03760154 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 2,951E-03 0,03944066 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 2,951E-03 0,03922275 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 2,951E-03 0,03900724 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 2,967E-03 0,03901156 ! inner ear development GO:0048839 79 50 2,000 3,143E-03 0,04110046 ! histone modification GO:0016570 91 50 2,000 3,143E-03 0,0408783 ! negative regulation of immune system process GO:0002683 95 50 2,000 3,143E-03 0,04065852 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 2,000 3,325E-03 0,04278587 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 3,392E-03 0,04340501 ! G1/S transition checkpoint GO:0031575 40 15 1,000 3,392E-03 0,04317536 ! intermediate filament cytoskeleton organization GO:0045104 31 15 1,000 3,392E-03 0,04294812 ! regulation of muscle contraction GO:0006937 81 52 2,000 3,514E-03 0,04426545 ! covalent chromatin modification GO:0016569 101 52 2,000 3,514E-03 0,0440349 ! cartilage development GO:0051216 90 52 2,000 3,514E-03 0,04380674 ! respiratory electron transport chain GO:0022904 76 53 2,000 3,709E-03 0,04599938 ! intermediate filament-based process GO:0045103 32 16 1,000 3,861E-03 0,0476419 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 3,861E-03 0,04739883 ! neuromuscular synaptic transmission GO:0007274 33 16 1,000 3,861E-03 0,04715822 ! positive regulation of caspase activity GO:0043280 95 55 2,000 4,119E-03 0,05004632 GO:0010952|positive regulation of peptidase activity, ! signal complex assembly GO:0007172 41 17 1,000 4,359E-03 0,05270636 ! regulation of survival gene product expression GO:0045884 33 17 1,000 4,359E-03 0,05244283 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 4,359E-03 0,05218192 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 4,359E-03 0,05192359 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 4,359E-03 0,05166781 ! lipid modification GO:0030258 97 57 2,000 4,554E-03 0,05371594 ! regulation of intracellular transport GO:0032386 101 57 2,000 4,554E-03 0,05345391 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 4,885E-03 0,05706068 ! DNA catabolic process GO:0006308 86 59 2,000 5,017E-03 0,05831727 ! integrin-mediated signaling pathway GO:0007229 135 59 2,000 5,017E-03 0,0580369 ! regulation of heart contraction GO:0008016 110 60 2,000 5,259E-03 0,06054118 ! protein amino acid autophosphorylation GO:0046777 141 60 2,000 5,259E-03 0,06025289 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 5,259E-03 0,05996733 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 1,000 5,439E-03 0,06173185 ! neuromuscular junction development GO:0007528 34 19 1,000 5,439E-03 0,06144203 ! G1 phase GO:0051318 40 19 1,000 5,439E-03 0,06115491 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 1,000 5,439E-03 0,06087047 ! purine nucleotide catabolic process GO:0006195 29 19 1,000 5,439E-03 0,06058866 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 6,021E-03 0,06675441 ! protein amino acid acetylation GO:0006473 39 20 1,000 6,021E-03 0,0664482 ! response to alkaloid GO:0043279 38 20 1,000 6,021E-03 0,06614478 ! cellular response to starvation GO:0009267 33 20 1,000 6,021E-03 0,06584413 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 6,021E-03 0,06554619 ! peptidyl-serine modification GO:0018209 43 20 1,000 6,021E-03 0,06525094 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 6,629E-03 0,0715218 ! lung development GO:0030324 144 67 2,000 7,146E-03 0,07676041 ! positive regulation of B cell activation GO:0050871 38 22 1,000 7,264E-03 0,07767694 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 7,264E-03 0,07733324 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 7,264E-03 0,07699256 ! protein stabilization GO:0050821 39 22 1,000 7,264E-03 0,07665488 ! positive regulation of DNA replication GO:0045740 43 23 1,000 7,926E-03 0,08326973 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 7,926E-03 0,08290769 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 7,926E-03 0,08254878 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 7,926E-03 0,08219296 ! purine ribonucleoside metabolic process GO:0046128 34 23 1,000 7,926E-03 0,0818402 GO:0042278|purine nucleoside metabolic process, ! sex determination GO:0007530 47 23 1,000 7,926E-03 0,08149046 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 7,926E-03 0,08114369 ! synaptic vesicle transport GO:0048489 46 23 1,000 7,926E-03 0,08079986 ! nerve-nerve synaptic transmission GO:0007270 49 23 1,000 7,926E-03 0,08045893 ! negative regulation of catabolic process GO:0009895 50 23 1,000 7,926E-03 0,08012087 ! respiratory tube development GO:0030323 150 70 2,000 8,063E-03 0,08116808 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 8,613E-03 0,08634559 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 8,613E-03 0,08598731 ! regulation of caspase activity GO:0043281 122 72 2,000 8,71E-03 0,08660027 ! phosphoinositide metabolic process GO:0030384 128 72 2,000 8,71E-03 0,08624389 ! respiratory system development GO:0060541 153 72 2,000 8,71E-03 0,08589043 ! learning or memory GO:0007611 147 73 2,000 9,045E-03 0,08882873 ! myelination GO:0042552 45 25 1,000 9,326E-03 0,09121568 ! protein amino acid alkylation GO:0008213 53 25 1,000 9,326E-03 0,09084638 GO:0006479|protein amino acid methylation, ! receptor metabolic process GO:0043112 46 25 1,000 9,326E-03 0,09048007 ! response to starvation GO:0042594 42 25 1,000 9,326E-03 0,09011669 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 9,326E-03 0,08975623 ! somitogenesis GO:0001756 43 25 1,000 9,326E-03 0,08939863 ! meiosis GO:0007126 121 74 2,000 9,388E-03 0,08962992 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 2,000 9,388E-03 0,08927565 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 9,738E-03 0,09223798 ! meiotic cell cycle GO:0051321 122 75 2,000 9,738E-03 0,09187626 ! lymphocyte differentiation GO:0030098 167 75 2,000 9,738E-03 0,09151737 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 0,01006498 0,094227 ! insulin receptor signaling pathway GO:0008286 64 26 1,000 0,01006498 0,09386178 ! positive regulation of nuclear division GO:0051785 40 26 1,000 0,01006498 0,09349938 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 1,000 0,01006498 0,09313977 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 0,01082877 0,09982386 ! protein amino acid acylation GO:0043543 55 27 1,000 0,01082877 0,09944285 ! male gonad development GO:0008584 44 27 1,000 0,01082877 0,09906474 ! regulation of peptidase activity GO:0052547 134 79 2,000 0,01121229 0,10218476 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 2,000 0,01121229 0,10179916 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 0,01161736 0,10508029 ! T cell activation GO:0042110 168 81 2,000 0,01199533 0,10809279 ! response to hypoxia GO:0001666 171 81 2,000 0,01199533 0,10768946 ! response to nutrient GO:0007584 125 82 2,000 0,01239835 0,11089383 ! cellular iron ion homeostasis GO:0006879 51 29 1,000 0,01243042 0,11076882 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 0,01243042 0,11036008 ! response to oxygen levels GO:0070482 176 83 2,000 0,01280907 0,11330376 ! regulation of ligase activity GO:0051340 142 84 2,000 0,0132275 0,11657646 ! ensheathment of neurons GO:0007272 57 30 1,000 0,01326765 0,11650348 GO:0008366|axon ensheathment, ! response to heat GO:0009408 50 30 1,000 0,01326765 0,11607983 ! oxidative phosphorylation GO:0006119 133 86 2,000 0,0140876 0,1228071 ! mitochondrion organization GO:0007005 148 86 2,000 0,0140876 0,12236375 ! iron ion homeostasis GO:0055072 54 31 1,000 0,01412874 0,12227963 ! erythrocyte differentiation GO:0030218 55 31 1,000 0,01412874 0,12184135 ! regulation of protein transport GO:0051223 154 87 2,000 0,01452929 0,12484815 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 135 88 2,000 0,01497878 0,12825247 ! spindle organization GO:0007051 46 32 1,000 0,01501338 0,1280929 ! metanephros development GO:0001656 74 32 1,000 0,01501338 0,12764027 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,01501338 0,12719083 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 0,01501338 0,12674455 ! regulation of ARF GTPase activity GO:0032312 65 32 1,000 0,01501338 0,12630139 ! peripheral nervous system development GO:0007422 64 32 1,000 0,01501338 0,12586131 ! BMP signaling pathway GO:0030509 64 32 1,000 0,01501338 0,1254243 ! hindbrain development GO:0030902 61 32 1,000 0,01501338 0,1249903 ! regulation of cell adhesion GO:0030155 212 89 2,000 0,01543607 0,12806614 ! ossification GO:0001503 188 90 2,000 0,01590117 0,13147156 ! regulation of cell cycle process GO:0010564 149 90 2,000 0,01590117 0,13102132 ! sex differentiation GO:0007548 145 90 2,000 0,01590117 0,13057415 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 0,01592128 0,13029459 ! cell fate specification GO:0001708 52 33 1,000 0,01592128 0,12985292 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01592128 0,12941422 ! bone development GO:0060348 189 91 2,000 0,01637411 0,13264683 ! glial cell differentiation GO:0010001 63 34 1,000 0,01685214 0,13606127 ! regulation of defense response GO:0031347 149 92 2,000 0,01685489 0,13562829 ! positive regulation of MAP kinase activity GO:0043406 160 93 2,000 0,01734352 0,13909501 ! regulation of synaptic plasticity GO:0048167 64 35 1,000 0,01780566 0,142327 ! negative regulation of cell adhesion GO:0007162 81 35 1,000 0,01780566 0,14185571 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01780566 0,14138754 ! regulation of microtubule-based process GO:0032886 78 35 1,000 0,01780566 0,14092245 ! regulation of T cell activation GO:0050863 158 94 2,000 0,01784001 0,14073135 ! forebrain development GO:0030900 188 95 2,000 0,01834437 0,14423711 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,01878155 0,14719352 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 0,01878155 0,14671561 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! maintenance of protein location in cell GO:0032507 86 36 1,000 0,01878155 0,14624081 ! leukocyte differentiation GO:0002521 202 96 2,000 0,01885661 0,14635162 ! regulation of DNA metabolic process GO:0051052 178 97 2,000 0,01937673 0,14990489 ! regulation of protein localization GO:0032880 176 97 2,000 0,01937673 0,14942442 ! meiosis I GO:0007127 65 37 1,000 0,01977951 0,15204316 ! sister chromatid segregation GO:0000819 58 37 1,000 0,01977951 0,15155894 ! glycogen metabolic process GO:0005977 61 37 1,000 0,01977951 0,1510778 ! cellular response to insulin stimulus GO:0032869 82 37 1,000 0,01977951 0,15059971 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,02044065 0,15514262 GO:0060538|skeletal muscle organ development, ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,02079926 0,15736802 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,02079926 0,1568747 ! carbohydrate homeostasis GO:0033500 53 38 1,000 0,02079926 0,15638447 GO:0042593|glucose homeostasis, ! lipid homeostasis GO:0055088 67 38 1,000 0,02079926 0,15589729 ! nucleotide catabolic process GO:0009166 61 38 1,000 0,02079926 0,15541314 ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,02079926 0,15493198 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,02079926 0,1544538 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 62 38 1,000 0,02079926 0,15397855 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 0,02184052 0,16119106 ! learning GO:0007612 77 39 1,000 0,02184052 0,16069812 ! ear morphogenesis GO:0042471 60 39 1,000 0,02184052 0,16020819 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,02184052 0,15972123 ! segmentation GO:0035282 67 39 1,000 0,02184052 0,15923723 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,02184052 0,15875615 ! ribonucleoside metabolic process GO:0009119 55 40 1,000 0,02290299 0,1659777 ! maintenance of protein location GO:0045185 91 40 1,000 0,02290299 0,16547927 ! cytokinesis GO:0000910 72 40 1,000 0,02290299 0,16498382 ! gliogenesis GO:0042063 88 41 1,000 0,0239864 0,17227249 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,02509047 0,17966572 GO:0090047|positive regulation of transcription regulator activity, ! regulation of myeloid cell differentiation GO:0045637 98 42 1,000 0,02509047 0,17913259 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,02621493 0,18660688 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 0,02621493 0,18605642 ! energy reserve metabolic process GO:0006112 74 43 1,000 0,02621493 0,1855092 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,02621493 0,18496518 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 1,000 0,0273595 0,19247649 ! male sex differentiation GO:0046661 76 44 1,000 0,0273595 0,19191534 ! biopolymer methylation GO:0043414 84 44 1,000 0,0273595 0,19135744 ! maintenance of location in cell GO:0051651 97 44 1,000 0,0273595 0,19080278 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 0,02852391 0,19834836 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 1,000 0,02852391 0,19777675 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02888175 0,19968247 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02888175 0,19911032 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02888175 0,19854143 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02888175 0,19797579 ! neuron fate determination GO:0048664 7 5 0,000 0,02888175 0,19741336 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02888175 0,19685411 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02888175 0,19629803 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02888175 0,19574507 ! polyol transport GO:0015791 12 5 0,000 0,02888175 0,19519523 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02888175 0,19464846 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02888175 0,19410475 ! response to superoxide GO:0000303 10 5 0,000 0,02888175 0,19356407 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02888175 0,19302639 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02888175 0,19249169 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02888175 0,19195995 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02888175 0,19143113 ! female meiosis GO:0007143 7 5 0,000 0,02888175 0,19090522 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02888175 0,1903822 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02888175 0,18986203 ! cobalt ion transport GO:0006824 11 5 0,000 0,02888175 0,18934469 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02888175 0,18883017 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02888175 0,18831843 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02888175 0,18780946 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02888175 0,18730324 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02888175 0,18679973 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02888175 0,18629893 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02888175 0,18580081 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02888175 0,18530534 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02888175 0,1848125 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02888175 0,18432228 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02888175 0,18383466 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02888175 0,18334961 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02888175 0,18286711 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,02888175 0,18238714 ! negative chemotaxis GO:0050919 14 5 0,000 0,02888175 0,18190969 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02888175 0,18143473 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02888175 0,18096224 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02888175 0,18049221 ! behavioral response to pain GO:0048266 9 5 0,000 0,02888175 0,18002461 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02888175 0,17955943 ! Notch receptor processing GO:0007220 8 5 0,000 0,02888175 0,17909665 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02888175 0,17863625 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02888175 0,17817821 ! micturition GO:0060073 9 5 0,000 0,02888175 0,17772251 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02888175 0,17726914 ! copulation GO:0007620 9 5 0,000 0,02888175 0,17681807 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02888175 0,17636929 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02888175 0,17592279 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02888175 0,17547854 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02888175 0,17503653 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02888175 0,17459674 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02888175 0,17415915 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02888175 0,17372375 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02888175 0,17329053 ! grooming behavior GO:0007625 6 5 0,000 0,02888175 0,17285946 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02888175 0,17243052 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02888175 0,17200372 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02888175 0,17157902 ! response to protozoan GO:0001562 10 5 0,000 0,02888175 0,17115641 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02888175 0,17073588 ! lymph vessel development GO:0001945 10 5 0,000 0,02888175 0,17031741 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02888175 0,16990098 ! endochondral ossification GO:0001958 16 5 0,000 0,02888175 0,16948659 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02888175 0,16907421 ! parathyroid gland development GO:0060017 13 5 0,000 0,02888175 0,16866384 ! anagen GO:0042640 6 5 0,000 0,02888175 0,16825545 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02888175 0,16784904 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02888175 0,16744458 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02888175 0,16704207 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02888175 0,16664149 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02888175 0,16624283 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02888175 0,16584607 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02888175 0,16545119 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02888175 0,1650582 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02888175 0,16466706 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02888175 0,16427778 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02888175 0,16389033 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02888175 0,16350471 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02888175 0,16312089 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02888175 0,16273888 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02888175 0,16235865 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02888175 0,16198019 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02888175 0,16160349 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02888175 0,16122854 ! histidine catabolic process GO:0006548 6 5 0,000 0,02888175 0,16085533 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02888175 0,16048384 ! valine metabolic process GO:0006573 10 5 0,000 0,02888175 0,16011406 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02888175 0,15974598 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02888175 0,15937959 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02888175 0,15901488 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02888175 0,15865183 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02888175 0,15829044 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02888175 0,15793068 ! polyol catabolic process GO:0046174 7 5 0,000 0,02888175 0,15757257 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02888175 0,15721607 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02888175 0,15686118 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02888175 0,15650789 ! muscle cell migration GO:0014812 8 5 0,000 0,02888175 0,15615618 ! mitochondrial fission GO:0000266 8 5 0,000 0,02888175 0,15580606 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02888175 0,1554575 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02888175 0,15511049 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02888175 0,15476504 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02888175 0,15442111 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02888175 0,15407872 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02888175 0,15373783 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02888175 0,15339846 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02888175 0,15306058 ! response to food GO:0032094 6 5 0,000 0,02888175 0,15272418 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02888175 0,15238926 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02888175 0,1520558 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02888175 0,1517238 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02888175 0,15139325 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02888175 0,15106413 ! forebrain neuron development GO:0021884 13 5 0,000 0,02888175 0,15073645 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02888175 0,15041018 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02888175 0,15008532 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02888175 0,14976186 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02888175 0,14943979 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02888175 0,1491191 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02888175 0,14879979 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02888175 0,14848184 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02888175 0,14816525 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02888175 0,14785 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02888175 0,1475361 ! basic amino acid transport GO:0015802 11 5 0,000 0,02888175 0,14722352 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02888175 0,14691226 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02888175 0,14660232 ! depyrimidination GO:0045008 10 5 0,000 0,02888175 0,14629369 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02888175 0,14598635 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02888175 0,1456803 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02888175 0,14537553 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02888175 0,14507203 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02888175 0,14476979 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02888175 0,14446882 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02888175 0,14416909 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02888175 0,1438706 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02888175 0,14357335 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02888175 0,14327732 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02888175 0,14298251 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02888175 0,14268891 ! response to arsenic GO:0046685 10 5 0,000 0,02888175 0,14239652 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02888175 0,14210532 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02888175 0,14181531 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02888175 0,14152648 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02888175 0,14123882 ! response to cadmium ion GO:0046686 7 5 0,000 0,02888175 0,14095234 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02888175 0,14066701 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02888175 0,14038283 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02888175 0,1400998 ! decidualization GO:0046697 11 5 0,000 0,02888175 0,13981791 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02888175 0,13953715 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02888175 0,13925752 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02888175 0,138979 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02888175 0,1387016 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02888175 0,1384253 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02888175 0,1381501 ! neural tube patterning GO:0021532 7 5 0,000 0,02888175 0,13787599 ! embryonic cleavage GO:0040016 6 5 0,000 0,02888175 0,13760297 ! peroxisome fission GO:0016559 5 5 0,000 0,02888175 0,13733103 ! histone demethylation GO:0016577 10 5 0,000 0,02888175 0,13706016 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02888175 0,13679036 ! mitotic recombination GO:0006312 9 5 0,000 0,02888175 0,13652161 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02888175 0,13625392 ! metaphase plate congression GO:0051310 7 5 0,000 0,02888175 0,13598728 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02888175 0,13572168 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02888175 0,13545712 ! enteric nervous system development GO:0048484 8 5 0,000 0,02888175 0,13519358 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02888175 0,13493107 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02888175 0,13466958 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02888175 0,13440909 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02888175 0,13414962 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02888175 0,13389114 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02888175 0,13363366 ! plasminogen activation GO:0031639 5 5 0,000 0,02888175 0,13337716 ! B cell homeostasis GO:0001782 13 5 0,000 0,02888175 0,13312165 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02888175 0,13286712 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02888175 0,13261355 ! metaphase GO:0051323 8 5 0,000 0,02888175 0,13236095 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02888175 0,13210932 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02888175 0,13185864 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02888175 0,1316089 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02888175 0,13136012 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02888175 0,13111227 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02888175 0,13086535 ! response to redox state GO:0051775 5 5 0,000 0,02888175 0,13061936 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02888175 0,1303743 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02888175 0,13013015 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02888175 0,12988692 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02888175 0,12964459 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02888175 0,12940317 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02888175 0,12916264 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02888175 0,12892301 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02888175 0,12868426 ! striatum development GO:0021756 9 5 0,000 0,02888175 0,1284464 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02888175 0,12820941 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02888175 0,1279733 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02888175 0,12773805 ! glial cell migration GO:0008347 11 5 0,000 0,02888175 0,12750367 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02888175 0,12727015 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02888175 0,12703748 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02888175 0,12680566 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02888175 0,12657468 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02888175 0,12634455 ! neuroprotection GO:0043526 6 5 0,000 0,02888175 0,12611525 ! neural plate development GO:0001840 8 5 0,000 0,02888175 0,12588678 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02888175 0,12565913 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02888175 0,12543231 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02888175 0,12520631 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02888175 0,12498112 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02888175 0,12475673 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02888175 0,12453316 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02888175 0,12431038 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02888175 0,1240884 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02888175 0,1238672 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02888175 0,1236468 ! spindle assembly GO:0051225 6 5 0,000 0,02888175 0,12342718 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02888175 0,12320834 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02888175 0,12299027 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02888175 0,12277297 ! drug metabolic process GO:0017144 6 5 0,000 0,02888175 0,12255644 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02888175 0,12234067 ! organ regeneration GO:0031100 7 5 0,000 0,02888175 0,12212566 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02888175 0,12191141 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02888175 0,1216979 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02888175 0,12148514 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,0297079 0,12474206 ! pigmentation GO:0043473 100 46 1,000 0,0297079 0,12452474 ! response to insulin stimulus GO:0032868 95 46 1,000 0,0297079 0,12430817 ! endosome transport GO:0016197 108 47 1,000 0,03091119 0,12911861 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,03091119 0,12889484 ! methylation GO:0032259 90 47 1,000 0,03091119 0,12867183 ! regulation of ARF protein signal transduction GO:0032012 102 48 1,000 0,03213353 0,13352895 ! regulation of action potential GO:0001508 95 49 1,000 0,03337464 0,13844723 ! response to temperature stimulus GO:0009266 76 49 1,000 0,03337464 0,13820894 ! detection of abiotic stimulus GO:0009582 74 49 1,000 0,03337464 0,13797147 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03455779 0,14261757 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03455779 0,14237336 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03455779 0,14212999 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03455779 0,14188745 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03455779 0,14164573 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03455779 0,14140484 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03455779 0,14116476 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03455779 0,1409255 ! sleep GO:0030431 13 6 0,000 0,03455779 0,14068705 ! response to oxygen radical GO:0000305 11 6 0,000 0,03455779 0,1404494 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03455779 0,14021255 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03455779 0,13997651 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03455779 0,13974125 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03455779 0,13950679 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03455779 0,13927311 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03455779 0,13904021 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03455779 0,13880809 ! forebrain regionalization GO:0021871 8 6 0,000 0,03455779 0,13857674 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03455779 0,13834616 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03455779 0,13811635 ! response to zinc ion GO:0010043 9 6 0,000 0,03455779 0,13788731 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03455779 0,13765902 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03455779 0,13743148 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03455779 0,13720469 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03455779 0,13697866 ! malate metabolic process GO:0006108 11 6 0,000 0,03455779 0,13675336 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03455779 0,13652881 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03455779 0,13630499 ! protein refolding GO:0042026 15 6 0,000 0,03455779 0,13608191 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03455779 0,13585955 ! opsonization GO:0008228 8 6 0,000 0,03455779 0,13563792 ! mating behavior GO:0007617 7 6 0,000 0,03455779 0,13541701 ! neuron remodeling GO:0016322 15 6 0,000 0,03455779 0,13519682 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03455779 0,13497735 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,03455779 0,13475858 ! equilibrioception GO:0050957 14 6 0,000 0,03455779 0,13454053 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03455779 0,13432317 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03455779 0,13410652 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03455779 0,13389057 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,03455779 0,13367531 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03455779 0,13346075 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03455779 0,13324687 ! toxin metabolic process GO:0009404 11 6 0,000 0,03455779 0,13303367 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03455779 0,13282116 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03455779 0,13260932 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03455779 0,13239816 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03455779 0,13218767 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03455779 0,13197785 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03455779 0,13176869 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03455779 0,1315602 ! thymic T cell selection GO:0045061 12 6 0,000 0,03455779 0,13135236 ! protein lipoylation GO:0009249 10 6 0,000 0,03455779 0,13114518 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03455779 0,13093865 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03455779 0,13073278 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03455779 0,13052754 ! glutamate catabolic process GO:0006538 10 6 0,000 0,03455779 0,13032295 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03455779 0,13011901 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03455779 0,1299157 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03455779 0,12971302 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03455779 0,12951097 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03455779 0,12930956 ! hyperosmotic response GO:0006972 9 6 0,000 0,03455779 0,12910877 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03455779 0,1289086 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03455779 0,12870905 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03455779 0,12851012 ! urea metabolic process GO:0019627 7 6 0,000 0,03455779 0,1283118 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03455779 0,12811409 ! neutrophil activation GO:0042119 8 6 0,000 0,03455779 0,12791699 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03455779 0,1277205 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03455779 0,12752461 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03455779 0,12732932 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03455779 0,12713463 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03455779 0,12694053 ! neuron apoptosis GO:0051402 9 6 0,000 0,03455779 0,12674702 ! nucleoside salvage GO:0043174 9 6 0,000 0,03455779 0,1265541 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03455779 0,12636177 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03455779 0,12617002 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03455779 0,12597886 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03455779 0,12578827 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,03455779 0,12559826 ! carnitine transport GO:0015879 10 6 0,000 0,03455779 0,12540882 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03455779 0,12521995 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03455779 0,12503165 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03455779 0,12484391 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03455779 0,12465674 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03455779 0,12447013 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03455779 0,12428407 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03455779 0,12409857 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03455779 0,12391363 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03455779 0,12372923 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03455779 0,12354539 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03455779 0,12336208 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,03455779 0,12317933 ! neural nucleus development GO:0048857 14 6 0,000 0,03455779 0,12299711 ! response to UV-C GO:0010225 11 6 0,000 0,03455779 0,12281543 ! astrocyte development GO:0014002 15 6 0,000 0,03455779 0,12263428 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03455779 0,12245367 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03455779 0,1222736 ! interaction with symbiont GO:0051702 13 6 0,000 0,03455779 0,12209405 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03455779 0,12191502 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03455779 0,12173652 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03455779 0,12155855 ! response to copper ion GO:0046688 10 6 0,000 0,03455779 0,12138109 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03455779 0,12120415 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03455779 0,12102772 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03455779 0,12085181 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03455779 0,12067641 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03455779 0,12050151 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03455779 0,12032713 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03455779 0,12015324 ! hair follicle maturation GO:0048820 7 6 0,000 0,03455779 0,11997986 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03455779 0,11980698 ! Schwann cell development GO:0014044 15 6 0,000 0,03455779 0,1196346 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03455779 0,11946271 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03455779 0,11929131 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,03455779 0,11912041 ! subpallium development GO:0021544 10 6 0,000 0,03455779 0,11894999 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03455779 0,11878006 ! histone ubiquitination GO:0016574 8 6 0,000 0,03455779 0,11861062 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03455779 0,11844166 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03455779 0,11827318 ! G2 phase GO:0051319 16 6 0,000 0,03455779 0,11810518 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03455779 0,11793765 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03455779 0,1177706 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03455779 0,11760402 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03455779 0,11743792 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03455779 0,11727228 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03455779 0,11710711 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03455779 0,1169424 ! receptor internalization GO:0031623 10 6 0,000 0,03455779 0,11677815 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03455779 0,11661437 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03455779 0,11645104 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03455779 0,11628817 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03455779 0,11612576 ! protein deubiquitination GO:0016579 14 6 0,000 0,03455779 0,1159638 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03455779 0,11580229 ! protein destabilization GO:0031648 9 6 0,000 0,03455779 0,11564123 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03455779 0,11548062 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03455779 0,11532045 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03455779 0,11516073 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03455779 0,11500145 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03455779 0,1148426 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03455779 0,1146842 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03455779 0,11452623 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03455779 0,1143687 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03455779 0,1142116 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03455779 0,11405493 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03455779 0,11389869 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03455779 0,11374288 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03455779 0,11358749 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03455779 0,11343253 ! catecholamine transport GO:0051937 9 6 0,000 0,03455779 0,11327799 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03455779 0,11312387 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03455779 0,11297017 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03455779 0,11281689 ! maternal placenta development GO:0001893 12 6 0,000 0,03455779 0,11266402 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03455779 0,11251156 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03455779 0,11235952 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03455779 0,11220789 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03455779 0,11205666 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03455779 0,11190585 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03455779 0,11175544 ! positive regulation of binding GO:0051099 78 51 1,000 0,0359122 0,11597954 ! viral infectious cycle GO:0019058 99 51 1,000 0,0359122 0,11582407 ! chromatin remodeling GO:0006338 109 51 1,000 0,0359122 0,11566902 ! vesicle organization GO:0016050 107 51 1,000 0,0359122 0,11551438 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,03720813 0,11952305 ! synapse organization GO:0050808 85 52 1,000 0,03720813 0,11936368 ! regulation of translational initiation GO:0006446 82 53 1,000 0,03852182 0,12341345 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,03985303 0,12750848 GO:0010863|positive regulation of phospholipase C activity, ! heterocycle catabolic process GO:0046700 85 54 1,000 0,03985303 0,12733915 ! tRNA transcription GO:0009304 14 7 0,000 0,04020084 0,12828013 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04020084 0,12811022 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04020084 0,12794077 ! regulation of helicase activity GO:0051095 15 7 0,000 0,04020084 0,12777176 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,04020084 0,12760319 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04020084 0,12743507 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04020084 0,12726739 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04020084 0,12710016 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04020084 0,12693336 ! prostate gland development GO:0030850 13 7 0,000 0,04020084 0,126767 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04020084 0,12660107 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04020084 0,12643558 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04020084 0,12627052 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04020084 0,12610589 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04020084 0,12594169 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04020084 0,12577792 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04020084 0,12561457 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04020084 0,12545165 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04020084 0,12528914 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04020084 0,12512706 ! glycolipid transport GO:0046836 10 7 0,000 0,04020084 0,1249654 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04020084 0,12480415 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,04020084 0,12464332 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04020084 0,12448291 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04020084 0,1243229 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04020084 0,12416331 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04020084 0,12400413 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04020084 0,12384535 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04020084 0,12368698 ! mRNA stabilization GO:0048255 18 7 0,000 0,04020084 0,12352902 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,04020084 0,12337145 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04020084 0,12321429 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04020084 0,12305753 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,04020084 0,12290117 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04020084 0,1227452 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04020084 0,12258963 ! lipoprotein transport GO:0042953 14 7 0,000 0,04020084 0,12243445 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04020084 0,12227967 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04020084 0,12212528 ! rhythmic behavior GO:0007622 15 7 0,000 0,04020084 0,12197127 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04020084 0,12181766 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04020084 0,12166443 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04020084 0,12151158 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04020084 0,12135912 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,04020084 0,12120704 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04020084 0,12105534 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04020084 0,12090402 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04020084 0,12075308 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04020084 0,12060252 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04020084 0,12045233 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04020084 0,12030251 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04020084 0,12015307 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04020084 0,12000399 ! spinal cord patterning GO:0021511 13 7 0,000 0,04020084 0,11985529 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04020084 0,11970695 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04020084 0,11955899 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04020084 0,11941138 ! adrenal gland development GO:0030325 17 7 0,000 0,04020084 0,11926414 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04020084 0,11911727 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04020084 0,11897075 ! ovulation GO:0030728 9 7 0,000 0,04020084 0,11882459 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04020084 0,1186788 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04020084 0,11853336 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,04020084 0,11838827 ! microtubule nucleation GO:0007020 20 7 0,000 0,04020084 0,11824354 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04020084 0,11809917 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04020084 0,11795515 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04020084 0,11781147 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04020084 0,11766815 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04020084 0,11752518 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04020084 0,11738255 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04020084 0,11724027 ! galactose metabolic process GO:0006012 13 7 0,000 0,04020084 0,11709833 ! vesicle fusion GO:0006906 17 7 0,000 0,04020084 0,11695673 ! response to dietary excess GO:0002021 8 7 0,000 0,04020084 0,11681548 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04020084 0,11667457 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04020084 0,116534 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,04020084 0,11639377 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,04020084 0,11625387 ! organ growth GO:0035265 15 7 0,000 0,04020084 0,11611431 ! purine salvage GO:0043101 10 7 0,000 0,04020084 0,11597508 ! nucleoside transport GO:0015858 8 7 0,000 0,04020084 0,11583619 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04020084 0,11569763 ! parturition GO:0007567 14 7 0,000 0,04020084 0,1155594 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,04020084 0,1154215 ! rRNA modification GO:0000154 14 7 0,000 0,04020084 0,11528393 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04020084 0,11514669 ! spindle checkpoint GO:0031577 15 7 0,000 0,04020084 0,11500977 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,04020084 0,11487318 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04020084 0,11473692 ! macrophage differentiation GO:0030225 11 7 0,000 0,04020084 0,11460097 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04020084 0,11446535 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04020084 0,11433005 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,04020084 0,11419506 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04020084 0,1140604 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,04020084 0,11392605 ! fibrinolysis GO:0042730 10 7 0,000 0,04020084 0,11379202 ! eating behavior GO:0042755 7 7 0,000 0,04020084 0,11365831 ! B cell lineage commitment GO:0002326 21 7 0,000 0,04020084 0,11352491 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04020084 0,11339182 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04020084 0,11325904 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04020084 0,11312657 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04020084 0,11299442 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04020084 0,11286257 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04020084 0,11273102 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,04020084 0,11259979 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04020084 0,11246886 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04020084 0,11233823 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04020084 0,11220791 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04020084 0,11207789 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04020084 0,11194817 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04020084 0,11181875 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04020084 0,11168963 ! regulation of meiosis GO:0040020 12 7 0,000 0,04020084 0,11156081 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04020084 0,11143228 ! T cell lineage commitment GO:0002360 16 7 0,000 0,04020084 0,11130405 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04020084 0,11117611 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04020084 0,11104847 ! oxygen homeostasis GO:0032364 12 7 0,000 0,04020084 0,11092112 ! transcription termination GO:0006353 13 7 0,000 0,04020084 0,11079407 ! response to tumor cell GO:0002347 13 7 0,000 0,04020084 0,1106673 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,04020084 0,11054082 ! anaphase GO:0051322 17 7 0,000 0,04020084 0,11041463 GO:0000090|mitotic anaphase, ! axonal fasciculation GO:0007413 18 7 0,000 0,04020084 0,11028873 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,04020084 0,11016312 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04020084 0,11003779 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,04020084 0,10991275 ! diuresis GO:0030146 12 7 0,000 0,04020084 0,10978799 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04020084 0,10966351 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04020084 0,10953932 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04020084 0,10941541 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,04020084 0,10929177 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,04020084 0,10916842 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04020084 0,10904534 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04020084 0,10892254 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04020084 0,10880002 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04020084 0,10867777 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04020084 0,1085558 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04020084 0,1084341 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04020084 0,10831268 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,04020084 0,10819152 ! lymph node development GO:0048535 10 7 0,000 0,04020084 0,10807064 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04020084 0,10795002 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04020084 0,10782968 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04020084 0,1077096 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04020084 0,10758979 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04020084 0,10747024 ! adult feeding behavior GO:0008343 9 7 0,000 0,04020084 0,10735096 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,04020084 0,10723195 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04020084 0,1071132 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04020084 0,10699471 ! muscle adaptation GO:0043500 14 7 0,000 0,04020084 0,10687649 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04020084 0,10675852 ! retina homeostasis GO:0001895 12 7 0,000 0,04020084 0,10664082 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04020084 0,10652337 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04020084 0,10640618 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04020084 0,10628925 ! protein prenylation GO:0018342 18 7 0,000 0,04020084 0,10617258 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04020084 0,10605616 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04020084 0,10594 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04020084 0,10582409 ! chloride transport GO:0006821 90 55 1,000 0,0412015 0,10833968 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,0412015 0,1082214 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,0412015 0,10810338 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,0412015 0,10798562 ! aging GO:0007568 103 55 1,000 0,0412015 0,10786812 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,04256699 0,11132194 ! regulation of DNA replication GO:0006275 101 56 1,000 0,04256699 0,11120107 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,04256699 0,11108046 ! muscle fiber development GO:0048747 112 57 1,000 0,04394926 0,11456331 ! positive regulation of cell migration GO:0030335 126 57 1,000 0,04394926 0,11443932 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,04394926 0,1143156 ! maintenance of location GO:0051235 118 57 1,000 0,04394926 0,11419215 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,04534808 0,11769954 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,04581109 0,11877315 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,04581109 0,1186453 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,04581109 0,11851772 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,04581109 0,11839042 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,04581109 0,11826339 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04581109 0,11813664 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04581109 0,11801015 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,04581109 0,11788394 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,04581109 0,11775799 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,04581109 0,11763232 ! meiotic prophase I GO:0007128 13 8 0,000 0,04581109 0,11750691 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04581109 0,11738177 ! oligopeptide transport GO:0006857 15 8 0,000 0,04581109 0,1172569 ! UTP metabolic process GO:0046051 8 8 0,000 0,04581109 0,11713229 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,04581109 0,11700794 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,04581109 0,11688386 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,04581109 0,11676005 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04581109 0,11663649 ! succinate metabolic process GO:0006105 14 8 0,000 0,04581109 0,1165132 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04581109 0,11639016 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,04581109 0,11626739 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04581109 0,11614487 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,04581109 0,11602261 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04581109 0,11590061 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04581109 0,11577887 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,04581109 0,11565738 ! reflex GO:0060004 16 8 0,000 0,04581109 0,11553615 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,04581109 0,11541517 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,04581109 0,11529444 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04581109 0,11517396 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,04581109 0,11505374 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,04581109 0,11493377 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,04581109 0,11481404 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04581109 0,11469457 ! pigment granule organization GO:0048753 16 8 0,000 0,04581109 0,11457535 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04581109 0,11445637 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,04581109 0,11433764 ! astrocyte differentiation GO:0048708 18 8 0,000 0,04581109 0,11421915 ! histidine metabolic process GO:0006547 16 8 0,000 0,04581109 0,11410091 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04581109 0,11398292 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,04581109 0,11386517 ! glycine catabolic process GO:0006546 13 8 0,000 0,04581109 0,11374766 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,04581109 0,11363039 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,04581109 0,11351337 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,04581109 0,11339659 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,04581109 0,11328004 ! melanin metabolic process GO:0006582 15 8 0,000 0,04581109 0,11316374 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,04581109 0,11304767 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04581109 0,11293185 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04581109 0,11281626 ! macrophage activation GO:0042116 12 8 0,000 0,04581109 0,1127009 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04581109 0,11258578 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,04581109 0,1124709 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04581109 0,11235625 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,04581109 0,11224184 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,04581109 0,11212765 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04581109 0,1120137 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,04581109 0,11189998 ! osteoblast development GO:0002076 16 8 0,000 0,04581109 0,11178649 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,04581109 0,11167323 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,04581109 0,11156021 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,04581109 0,1114474 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,04581109 0,11133483 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,04581109 0,11122249 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04581109 0,11111037 ! response to UV-B GO:0010224 16 8 0,000 0,04581109 0,11099847 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,04581109 0,1108868 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04581109 0,11077536 ! intermediate filament organization GO:0045109 12 8 0,000 0,04581109 0,11066414 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,04581109 0,11055314 ! cellular extravasation GO:0045123 12 8 0,000 0,04581109 0,11044237 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,04581109 0,11033181 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,04581109 0,11022148 ! response to antibiotic GO:0046677 11 8 0,000 0,04581109 0,11011137 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,04581109 0,11000148 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,04581109 0,10989181 ! DNA topological change GO:0006265 12 8 0,000 0,04581109 0,10978235 ! response to tropane GO:0014073 15 8 0,000 0,04581109 0,10967312 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,04581109 0,1095641 ! melanosome transport GO:0032402 13 8 0,000 0,04581109 0,1094553 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,04581109 0,10934671 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04581109 0,10923834 ! mast cell activation GO:0045576 14 8 0,000 0,04581109 0,10913018 ! multicellular organismal aging GO:0010259 18 8 0,000 0,04581109 0,10902224 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,04581109 0,10891451 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,04581109 0,10880699 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,04581109 0,10869969 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04581109 0,10859259 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04581109 0,10848571 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,04581109 0,10837904 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04581109 0,10827258 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04581109 0,10816632 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,04581109 0,10806028 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,04581109 0,10795444 ! intracellular lipid transport GO:0032365 13 8 0,000 0,04581109 0,10784881 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04581109 0,10774339 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,04581109 0,10763817 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,04581109 0,10753315 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,04581109 0,10742835 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04581109 0,10732374 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,04581109 0,10721934 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,04581109 0,10711514 ! hormone catabolic process GO:0042447 17 8 0,000 0,04581109 0,10701115 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04581109 0,10690735 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,04581109 0,10680376 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,04581109 0,10670037 ! blastocyst growth GO:0001832 19 8 0,000 0,04581109 0,10659718 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04581109 0,10649419 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04581109 0,10639139 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,04581109 0,1062888 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04581109 0,1061864 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04581109 0,1060842 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,04581109 0,1059822 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,04581109 0,10588039 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,04581109 0,10577877 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,04581109 0,10567736 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,04581109 0,10557613 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,04581109 0,1054751 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04581109 0,10537427 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,04581109 0,10527362 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04581109 0,10517317 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04581109 0,10507291 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04581109 0,10497284 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,04581109 0,10487296 ! skeletal system morphogenesis GO:0048705 105 59 1,000 0,04676319 0,1069508 ! establishment of organelle localization GO:0051656 109 59 1,000 0,04676319 0,10684923 ! nucleoside metabolic process GO:0009116 81 60 1,000 0,04819437 0,11001486 ! camera-type eye development GO:0043010 116 60 1,000 0,04819437 0,10991058 ! kidney development GO:0001822 122 60 1,000 0,04819437 0,1098065 ! response to peptide hormone stimulus GO:0043434 122 61 1,000 0,04964138 0,11299638 ! viral reproductive process GO:0022415 126 62 1,000 0,051104 0,1162157 ! gonad development GO:0008406 98 62 1,000 0,051104 0,11610596 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,051104 0,11599643 ! regulation of developmental growth GO:0048638 15 9 0,000 0,05138873 0,11653279 ! axon extension GO:0048675 15 9 0,000 0,05138873 0,11642306 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05138873 0,11631354 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,05138873 0,11620422 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05138873 0,11609511 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,05138873 0,1159862 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05138873 0,1158775 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05138873 0,115769 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05138873 0,1156607 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05138873 0,11555261 ! phosphate transport GO:0006817 19 9 0,000 0,05138873 0,11544472 ! reproductive behavior GO:0019098 19 9 0,000 0,05138873 0,11533703 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05138873 0,11522954 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05138873 0,11512225 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05138873 0,11501515 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05138873 0,11490826 ! GTP metabolic process GO:0046039 9 9 0,000 0,05138873 0,11480157 ! RNA methylation GO:0001510 15 9 0,000 0,05138873 0,11469508 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05138873 0,11458878 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05138873 0,11448268 ! artery development GO:0060840 24 9 0,000 0,05138873 0,11437677 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05138873 0,11427106 ! regulation of glycolysis GO:0006110 21 9 0,000 0,05138873 0,11416555 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05138873 0,11406023 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05138873 0,11395511 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05138873 0,11385018 ! chemosensory behavior GO:0007635 20 9 0,000 0,05138873 0,11374544 ! microtubule bundle formation GO:0001578 21 9 0,000 0,05138873 0,11364089 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05138873 0,11353654 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05138873 0,11343238 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05138873 0,11332841 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,05138873 0,11322463 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05138873 0,11312104 ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05138873 0,11301763 ! protein targeting to ER GO:0045047 22 9 0,000 0,05138873 0,11291442 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05138873 0,1128114 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05138873 0,11270856 ! T cell selection GO:0045058 23 9 0,000 0,05138873 0,11260591 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,05138873 0,11250345 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05138873 0,11240117 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05138873 0,11229908 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05138873 0,11219718 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05138873 0,11209546 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05138873 0,11199392 ! mannose metabolic process GO:0006013 13 9 0,000 0,05138873 0,11189257 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05138873 0,1117914 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05138873 0,11169042 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05138873 0,11158961 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05138873 0,11148899 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05138873 0,11138855 ! ruffle organization GO:0031529 15 9 0,000 0,05138873 0,11128829 ! retinol metabolic process GO:0042572 18 9 0,000 0,05138873 0,11118821 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05138873 0,11108831 ! behavioral fear response GO:0001662 22 9 0,000 0,05138873 0,11098859 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05138873 0,11088905 GO:0007351|tripartite regional subdivision, ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05138873 0,11078969 GO:0030204|chondroitin sulfate metabolic process, ! protein heterooligomerization GO:0051291 16 9 0,000 0,05138873 0,1106905 ! oligodendrocyte development GO:0014003 10 9 0,000 0,05138873 0,1105915 ! segment specification GO:0007379 13 9 0,000 0,05138873 0,11049266 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05138873 0,11039401 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05138873 0,11029553 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05138873 0,11019723 ! response to amine stimulus GO:0014075 13 9 0,000 0,05138873 0,1100991 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05138873 0,11000115 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05138873 0,10990337 ! erythrocyte development GO:0048821 15 9 0,000 0,05138873 0,10980577 ! gas homeostasis GO:0033483 16 9 0,000 0,05138873 0,10970833 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,05138873 0,10961107 ! renal water homeostasis GO:0003091 14 9 0,000 0,05138873 0,10951399 ! postreplication repair GO:0006301 22 9 0,000 0,05138873 0,10941707 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05138873 0,10932033 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05138873 0,10922376 ! icosanoid secretion GO:0032309 15 9 0,000 0,05138873 0,10912735 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05138873 0,10903112 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 15 9 0,000 0,05138873 0,10893506 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05138873 0,10883917 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05138873 0,10874344 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05138873 0,10864788 ! sterol catabolic process GO:0016127 11 9 0,000 0,05138873 0,10855249 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05138873 0,10845727 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05138873 0,10836222 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05138873 0,10826733 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,05138873 0,10817261 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,05138873 0,10807805 ! musculoskeletal movement GO:0050881 14 9 0,000 0,05138873 0,10798366 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05138873 0,10788943 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05138873 0,10779537 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05138873 0,10770147 ! purine base metabolic process GO:0006144 21 9 0,000 0,05138873 0,10760774 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05138873 0,10751417 ! pigment granule transport GO:0051904 17 9 0,000 0,05138873 0,10742076 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05138873 0,10732751 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05138873 0,10723442 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05138873 0,1071415 ! mitochondrion localization GO:0051646 15 9 0,000 0,05138873 0,10704874 ! regulation of mitosis GO:0007088 105 63 1,000 0,05258198 0,10943965 GO:0051783|regulation of nuclear division, ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,05258198 0,10934506 ! detection of external stimulus GO:0009581 91 63 1,000 0,05258198 0,10925064 ! positive regulation of cell motion GO:0051272 146 64 1,000 0,0540751 0,112256 ! regulation of cytokine biosynthetic process GO:0042035 95 65 1,000 0,05558315 0,11528712 ! germ cell development GO:0007281 118 65 1,000 0,05558315 0,11518782 ! myeloid cell differentiation GO:0030099 111 65 1,000 0,05558315 0,11508869 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,05693396 0,11778426 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,05693396 0,11768307 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,05693396 0,11758206 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,05693396 0,11748122 ! synapsis GO:0007129 13 10 0,000 0,05693396 0,11738055 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,05693396 0,11728005 ! N-glycan processing GO:0006491 20 10 0,000 0,05693396 0,11717973 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,05693396 0,11707957 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,05693396 0,11697959 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,05693396 0,11687978 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,05693396 0,11678014 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,05693396 0,11668066 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,05693396 0,11658136 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,05693396 0,11648223 ! androgen metabolic process GO:0008209 17 10 0,000 0,05693396 0,11638326 ! phospholipid efflux GO:0033700 16 10 0,000 0,05693396 0,11628446 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,05693396 0,11618583 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,05693396 0,11608737 ! lung alveolus development GO:0048286 26 10 0,000 0,05693396 0,11598908 ! pathogenesis GO:0009405 13 10 0,000 0,05693396 0,11589095 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05693396 0,11579298 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,05693396 0,11569518 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,05693396 0,11559755 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,05693396 0,11550008 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,05693396 0,11540278 ! endoderm development GO:0007492 16 10 0,000 0,05693396 0,11530564 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,05693396 0,11520866 ! arginine catabolic process GO:0006527 13 10 0,000 0,05693396 0,11511185 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,05693396 0,1150152 ! proline metabolic process GO:0006560 13 10 0,000 0,05693396 0,11491871 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,05693396 0,11482238 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,05693396 0,11472621 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,05693396 0,11463021 ! V(D)J recombination GO:0033151 28 10 0,000 0,05693396 0,11453436 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05693396 0,11443868 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,05693396 0,11434315 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,05693396 0,11424779 ! B cell proliferation GO:0042100 18 10 0,000 0,05693396 0,11415258 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,05693396 0,11405753 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,05693396 0,11396264 ! multicellular organism growth GO:0035264 18 10 0,000 0,05693396 0,11386791 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,05693396 0,11377334 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,05693396 0,11367892 ! epithelial cell development GO:0002064 20 10 0,000 0,05693396 0,11358466 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,05693396 0,11349055 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,05693396 0,1133966 ! macroautophagy GO:0016236 17 10 0,000 0,05693396 0,11330281 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,05693396 0,11320917 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,05693396 0,11311569 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,05693396 0,11302236 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,05693396 0,11292918 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,05693396 0,11283616 ! copper ion homeostasis GO:0055070 13 10 0,000 0,05693396 0,11274329 ! regulation of bone resorption GO:0045124 25 10 0,000 0,05693396 0,11265057 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,05693396 0,11255801 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,05693396 0,1124656 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,05693396 0,11237334 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,05693396 0,11228123 ! blastoderm segmentation GO:0007350 18 10 0,000 0,05693396 0,11218927 ! response to dsRNA GO:0043331 20 10 0,000 0,05693396 0,11209746 ! DNA ligation GO:0006266 19 10 0,000 0,05693396 0,1120058 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05693396 0,1119143 ! melanosome localization GO:0032400 16 10 0,000 0,05693396 0,11182294 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,05693396 0,11173173 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,05693396 0,11164067 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,05693396 0,11154975 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,05693396 0,11145899 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,05693396 0,11136837 ! mRNA cleavage GO:0006379 17 10 0,000 0,05693396 0,1112779 ! protein sumoylation GO:0016925 15 10 0,000 0,05693396 0,11118758 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,05693396 0,1110974 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05693396 0,11100737 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,05693396 0,11091749 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,05693396 0,11082775 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,05693396 0,11073816 ! salivary gland development GO:0007431 27 10 0,000 0,05693396 0,11064871 ! prophase GO:0051324 15 10 0,000 0,05693396 0,1105594 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05693396 0,11047024 ! apical protein localization GO:0045176 15 10 0,000 0,05693396 0,11038122 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,05693396 0,11029235 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,05693396 0,11020362 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,05693396 0,11011503 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05693396 0,11002659 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,05693396 0,10993828 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,05693396 0,10985012 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,05693396 0,1097621 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,05693396 0,10967422 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,05693396 0,10958648 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,05693396 0,10949888 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,05693396 0,10941142 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 23 10 0,000 0,05693396 0,1093241 ! oocyte development GO:0048599 17 10 0,000 0,05693396 0,10923692 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,05693396 0,10914988 ! blastocyst formation GO:0001825 17 10 0,000 0,05693396 0,10906298 ! cerebellar cortex development GO:0021695 15 10 0,000 0,05693396 0,10897621 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,05693396 0,10888959 ! activation of innate immune response GO:0002218 12 10 0,000 0,05693396 0,1088031 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,05693396 0,10871675 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,05693396 0,10863053 ! response to nicotine GO:0035094 20 10 0,000 0,05693396 0,10854445 ! establishment of cell polarity GO:0030010 16 10 0,000 0,05693396 0,10845851 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,05693396 0,1083727 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,05693396 0,10828703 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,05710589 0,10852825 ! actin filament organization GO:0007015 148 66 1,000 0,05710589 0,10844259 ! developmental maturation GO:0021700 116 66 1,000 0,05710589 0,10835707 ! cell projection assembly GO:0030031 120 66 1,000 0,05710589 0,10827168 ! chromosome segregation GO:0007059 113 67 1,000 0,0586431 0,11109866 ! homeostasis of number of cells GO:0048872 114 67 1,000 0,0586431 0,11101125 ! negative regulation of ligase activity GO:0051352 112 68 1,000 0,06019457 0,1138586 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 134 68 1,000 0,06019457 0,11376916 ! regulation of lipase activity GO:0060191 130 68 1,000 0,06019457 0,11367986 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 1,000 0,06019457 0,1135907 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,06176008 0,11645356 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 1,000 0,06176008 0,11636237 ! urogenital system development GO:0001655 137 69 1,000 0,06176008 0,11627132 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,06244695 0,11747252 ! respiratory burst GO:0045730 17 11 0,000 0,06244695 0,11738075 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06244695 0,11728911 ! neuron fate specification GO:0048665 17 11 0,000 0,06244695 0,11719763 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06244695 0,11710628 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06244695 0,11701507 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06244695 0,11692401 ! thyroid gland development GO:0030878 26 11 0,000 0,06244695 0,11683309 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06244695 0,11674231 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06244695 0,11665167 ! response to pain GO:0048265 24 11 0,000 0,06244695 0,11656118 ! T cell proliferation GO:0042098 26 11 0,000 0,06244695 0,11647082 ! blood vessel remodeling GO:0001974 29 11 0,000 0,06244695 0,1163806 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,06244695 0,11629052 ! bone resorption GO:0045453 16 11 0,000 0,06244695 0,11620058 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06244695 0,11611078 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06244695 0,11602112 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06244695 0,1159316 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06244695 0,11584222 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06244695 0,11575297 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06244695 0,11566386 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,06244695 0,11557489 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06244695 0,11548605 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06244695 0,11539735 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,06244695 0,11530879 ! lipid digestion GO:0044241 18 11 0,000 0,06244695 0,11522036 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06244695 0,11513207 ! UV protection GO:0009650 19 11 0,000 0,06244695 0,11504392 ! adult heart development GO:0007512 14 11 0,000 0,06244695 0,1149559 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06244695 0,11486801 ! temperature homeostasis GO:0001659 17 11 0,000 0,06244695 0,11478026 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06244695 0,11469264 ! negative regulation of ossification GO:0030279 26 11 0,000 0,06244695 0,11460515 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,06244695 0,1145178 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06244695 0,11443058 ! regulation of organ growth GO:0046620 13 11 0,000 0,06244695 0,1143435 ! pigment granule localization GO:0051875 20 11 0,000 0,06244695 0,11425654 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06244695 0,11416972 ! vasoconstriction GO:0042310 18 11 0,000 0,06244695 0,11408303 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06244695 0,11399648 ! embryonic axis specification GO:0000578 18 11 0,000 0,06244695 0,11391005 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06244695 0,11382375 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06244695 0,11373759 GO:0016180|snRNA processing, ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06244695 0,11365155 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,06244695 0,11356565 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06244695 0,11347988 ! zymogen activation GO:0031638 15 11 0,000 0,06244695 0,11339423 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06244695 0,11330871 ! neuroblast proliferation GO:0007405 24 11 0,000 0,06244695 0,11322333 ! nucleosome positioning GO:0016584 15 11 0,000 0,06244695 0,11313807 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06244695 0,11305294 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06244695 0,11296794 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06244695 0,11288306 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,06244695 0,11279831 ! acid secretion GO:0046717 18 11 0,000 0,06244695 0,1127137 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06244695 0,1126292 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06244695 0,11254484 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06244695 0,1124606 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06244695 0,11237648 ! oocyte differentiation GO:0009994 18 11 0,000 0,06244695 0,11229249 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06244695 0,11220863 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,06244695 0,11212489 ! cholesterol efflux GO:0033344 19 11 0,000 0,06244695 0,11204128 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06244695 0,11195779 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06244695 0,11187443 ! germ cell migration GO:0008354 25 11 0,000 0,06244695 0,11179119 ! embryonic gut development GO:0048566 15 11 0,000 0,06244695 0,11170807 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06244695 0,11162508 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06244695 0,11154221 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,06244695 0,11145946 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06244695 0,11137684 ! defense response to fungus GO:0050832 13 11 0,000 0,06244695 0,11129434 ! lysogeny GO:0030069 21 11 0,000 0,06244695 0,11121196 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06244695 0,1111297 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06244695 0,11104756 ! sequestering of metal ion GO:0051238 14 11 0,000 0,06244695 0,11096555 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06244695 0,11088366 ! regulation of embryonic development GO:0045995 27 11 0,000 0,06244695 0,11080188 ! nucleus localization GO:0051647 19 11 0,000 0,06244695 0,11072023 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06244695 0,1106387 ! reproductive structure development GO:0048608 113 71 1,000 0,06493235 0,11495749 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 1,000 0,06653869 0,11771477 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 1,000 0,06653869 0,11762828 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,06792789 0,11999597 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,06792789 0,11990793 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,06792789 0,11982002 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,06792789 0,11973224 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,06792789 0,11964459 ! virus-host interaction GO:0019048 29 12 0,000 0,06792789 0,11955707 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,06792789 0,11946967 ! cartilage condensation GO:0001502 20 12 0,000 0,06792789 0,1193824 ! mating GO:0007618 17 12 0,000 0,06792789 0,11929526 ! protein complex disassembly GO:0043241 27 12 0,000 0,06792789 0,11920825 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,06792789 0,11912136 ! hippocampus development GO:0021766 26 12 0,000 0,06792789 0,1190346 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,06792789 0,11894797 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06792789 0,11886146 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,06792789 0,11877508 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,06792789 0,11868882 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,06792789 0,11860269 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,06792789 0,11851669 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,06792789 0,1184308 ! drug transport GO:0015893 16 12 0,000 0,06792789 0,11834505 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,06792789 0,11825941 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,06792789 0,1181739 ! polyamine metabolic process GO:0006595 17 12 0,000 0,06792789 0,11808852 ! focal adhesion formation GO:0048041 35 12 0,000 0,06792789 0,11800326 ! mitotic spindle organization GO:0007052 21 12 0,000 0,06792789 0,11791812 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,06792789 0,1178331 ! forebrain cell migration GO:0021885 21 12 0,000 0,06792789 0,11774821 ! asymmetric protein localization GO:0008105 20 12 0,000 0,06792789 0,11766343 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,06792789 0,11757878 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,06792789 0,11749426 ! entry into host cell GO:0030260 32 12 0,000 0,06792789 0,11740985 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,06792789 0,11732556 ! monoamine transport GO:0015844 18 12 0,000 0,06792789 0,1172414 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06792789 0,11715735 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,06792789 0,11707343 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,06792789 0,11698963 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,06792789 0,11690594 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06792789 0,11682238 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,06792789 0,11673894 ! protein homotetramerization GO:0051289 21 12 0,000 0,06792789 0,11665561 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,06792789 0,1165724 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,06792789 0,11648932 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06792789 0,11640635 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,06792789 0,11632349 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,06792789 0,11624076 ! cranial nerve development GO:0021545 20 12 0,000 0,06792789 0,11615814 ! fucose catabolic process GO:0019317 22 12 0,000 0,06792789 0,11607565 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,06792789 0,11599326 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,06792789 0,115911 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06792789 0,11582885 ! gland morphogenesis GO:0022612 29 12 0,000 0,06792789 0,11574682 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,06792789 0,1156649 ! T cell homeostasis GO:0043029 25 12 0,000 0,06792789 0,1155831 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,06792789 0,11550142 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,06792789 0,11541985 ! spleen development GO:0048536 22 12 0,000 0,06792789 0,1153384 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,06792789 0,11525706 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,06792789 0,11517583 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,06792789 0,11509473 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,06792789 0,11501373 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,06792789 0,11493285 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,06792789 0,11485208 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,06792789 0,11477143 ! response to cold GO:0009409 17 12 0,000 0,06792789 0,11469088 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,06792789 0,11461046 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,06792789 0,11453014 ! axon guidance GO:0007411 139 73 1,000 0,06815822 0,11483801 ! eye development GO:0001654 143 74 1,000 0,06979074 0,11750631 ! organelle localization GO:0051640 136 74 1,000 0,06979074 0,11742414 ! cell-matrix adhesion GO:0007160 163 75 1,000 0,07143603 0,12010838 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,0730939 0,12281 ! regulation of catabolic process GO:0009894 161 76 1,000 0,0730939 0,1227243 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07337698 0,12311367 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,07337698 0,12302788 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07337698 0,12294221 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07337698 0,12285665 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,07337698 0,12277121 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,07337698 0,1226859 ! lipid localization GO:0010876 28 13 0,000 0,07337698 0,1226007 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,07337698 0,12251562 ! organelle fusion GO:0048284 32 13 0,000 0,07337698 0,12243066 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,07337698 0,12234581 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,07337698 0,12226109 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,07337698 0,12217648 ! endocrine pancreas development GO:0031018 22 13 0,000 0,07337698 0,12209198 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,07337698 0,12200761 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,07337698 0,12192335 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,07337698 0,1218392 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07337698 0,12175518 ! methionine metabolic process GO:0006555 27 13 0,000 0,07337698 0,12167127 ! plasma membrane organization GO:0007009 24 13 0,000 0,07337698 0,12158747 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,07337698 0,12150379 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,07337698 0,12142023 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,07337698 0,12133677 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,07337698 0,12125344 ! response to X-ray GO:0010165 25 13 0,000 0,07337698 0,12117022 ! cytokine metabolic process GO:0042107 22 13 0,000 0,07337698 0,12108711 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,07337698 0,12100412 ! exocrine system development GO:0035272 32 13 0,000 0,07337698 0,12092124 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,07337698 0,12083847 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,07337698 0,12075582 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,07337698 0,12067328 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,07337698 0,12059085 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,07337698 0,12050854 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,07337698 0,12042634 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,07337698 0,12034424 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,07337698 0,12026227 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,07337698 0,1201804 ! regulation of cellular pH GO:0030641 22 13 0,000 0,07337698 0,12009864 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07337698 0,120017 ! ribosome assembly GO:0042255 17 13 0,000 0,07337698 0,11993547 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,07337698 0,11985404 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,07337698 0,11977273 ! chromatin silencing GO:0006342 26 13 0,000 0,07337698 0,11969153 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,07337698 0,11961044 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07337698 0,11952946 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,07337698 0,11944858 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,07337698 0,11936782 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,07337698 0,11928717 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,07337698 0,11920662 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,07337698 0,11912619 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,07337698 0,11904586 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,07337698 0,11896564 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,07337698 0,11888553 ! embryonic placenta development GO:0001892 23 13 0,000 0,07337698 0,11880552 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,07337698 0,11872563 ! insulin secretion GO:0030073 23 13 0,000 0,07337698 0,11864584 ! actin filament polymerization GO:0030041 24 13 0,000 0,07337698 0,11856616 ! acrosome reaction GO:0007340 18 13 0,000 0,07337698 0,11848658 ! positive regulation of ligase activity GO:0051351 124 77 1,000 0,07476415 0,12064556 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,07476415 0,1205647 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,07644656 0,1231952 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 1,000 0,07814096 0,12584147 ! regulation of synaptic transmission GO:0050804 134 79 1,000 0,07814096 0,12575729 ! rRNA transcription GO:0009303 25 14 0,000 0,07879439 0,12672412 ! lactation GO:0007595 26 14 0,000 0,07879439 0,12663947 ! reproductive cellular process GO:0048610 20 14 0,000 0,07879439 0,12655493 ! tRNA modification GO:0006400 20 14 0,000 0,07879439 0,12647051 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,07879439 0,12638619 ! regulation of S phase GO:0033261 23 14 0,000 0,07879439 0,12630199 ! water transport GO:0006833 21 14 0,000 0,07879439 0,1262179 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,07879439 0,12613393 ! non-recombinational repair GO:0000726 25 14 0,000 0,07879439 0,12605006 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,07879439 0,12596631 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,07879439 0,12588266 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,07879439 0,12579913 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,07879439 0,12571571 ! RNA polyadenylation GO:0043631 30 14 0,000 0,07879439 0,1256324 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,07879439 0,1255492 ! palate development GO:0060021 31 14 0,000 0,07879439 0,12546611 ! regulated secretory pathway GO:0045055 23 14 0,000 0,07879439 0,12538313 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,07879439 0,12530026 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,07879439 0,1252175 ! arginine metabolic process GO:0006525 17 14 0,000 0,07879439 0,12513485 ! regulation of heart rate GO:0002027 24 14 0,000 0,07879439 0,1250523 ! organic alcohol transport GO:0015850 29 14 0,000 0,07879439 0,12496987 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,07879439 0,12488754 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,07879439 0,12480533 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,07879439 0,12472322 ! neutral amino acid transport GO:0015804 26 14 0,000 0,07879439 0,12464122 ! L-amino acid transport GO:0015807 30 14 0,000 0,07879439 0,12455932 ! bone mineralization GO:0030282 17 14 0,000 0,07879439 0,12447754 ! stem cell development GO:0048864 43 14 0,000 0,07879439 0,12439586 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,07879439 0,12431429 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,07879439 0,12423282 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,07879439 0,12415147 ! cerebellum development GO:0021549 21 14 0,000 0,07879439 0,12407022 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,07879439 0,12398907 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,07879439 0,12390803 ! response to gamma radiation GO:0010332 28 14 0,000 0,07879439 0,1238271 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,07879439 0,12374627 ! cofactor transport GO:0051181 26 14 0,000 0,07879439 0,12366555 ! NADP metabolic process GO:0006739 24 14 0,000 0,07879439 0,12358494 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,07879439 0,12350442 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,07879439 0,12342402 ! intestinal absorption GO:0050892 25 14 0,000 0,07879439 0,12334372 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,07879439 0,12326352 ! oxygen transport GO:0015671 21 14 0,000 0,07879439 0,12318342 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07879439 0,12310344 ! male genitalia development GO:0030539 24 14 0,000 0,07879439 0,12302355 ! regulation of RNA stability GO:0043487 32 14 0,000 0,07879439 0,12294377 ! regulation of axon extension GO:0030516 37 14 0,000 0,07879439 0,12286409 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,07879439 0,12278451 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,07984714 0,12434448 ! muscle cell differentiation GO:0042692 159 80 1,000 0,07984714 0,12426405 ! inorganic anion transport GO:0015698 138 80 1,000 0,07984714 0,12418372 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,08156491 0,12677336 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,08329407 0,12937736 ! cholesterol metabolic process GO:0008203 136 82 1,000 0,08329407 0,12929389 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,08329407 0,12921053 ! cellular response to hormone stimulus GO:0032870 167 82 1,000 0,08329407 0,12912728 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,0841803 0,13041713 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,0841803 0,13033321 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,0841803 0,13024939 ! superoxide anion generation GO:0042554 20 15 0,000 0,0841803 0,13016568 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,0841803 0,13008208 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,0841803 0,12999859 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,0841803 0,1299152 ! copper ion transport GO:0006825 20 15 0,000 0,0841803 0,12983192 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,0841803 0,12974875 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,0841803 0,12966569 ! sulfate transport GO:0008272 23 15 0,000 0,0841803 0,12958273 ! response to cAMP GO:0051591 22 15 0,000 0,0841803 0,12949987 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,0841803 0,12941713 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,0841803 0,12933448 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,0841803 0,12925195 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,0841803 0,12916952 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,0841803 0,12908719 ! response to hexose stimulus GO:0009746 22 15 0,000 0,0841803 0,12900497 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,0841803 0,12892285 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,0841803 0,12884084 ! pituitary gland development GO:0021983 29 15 0,000 0,0841803 0,12875893 ! vesicle coating GO:0006901 33 15 0,000 0,0841803 0,12867713 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,0841803 0,12859543 ! regulation of exocytosis GO:0017157 22 15 0,000 0,0841803 0,12851383 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,0841803 0,12843234 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,0841803 0,12835095 ! regulation of vasodilation GO:0042312 26 15 0,000 0,0841803 0,12826967 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,0841803 0,12818848 ! histone deacetylation GO:0016575 20 15 0,000 0,0841803 0,1281074 ! mRNA splice site selection GO:0006376 38 15 0,000 0,0841803 0,12802642 ! tissue regeneration GO:0042246 26 15 0,000 0,0841803 0,12794555 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,0841803 0,12786477 ! water homeostasis GO:0030104 27 15 0,000 0,0841803 0,1277841 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,0841803 0,12770353 ! muscle maintenance GO:0046716 26 15 0,000 0,0841803 0,12762306 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,0841803 0,1275427 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,0841803 0,12746243 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,0841803 0,12738227 ! dopamine metabolic process GO:0042417 35 15 0,000 0,0841803 0,1273022 ! heme biosynthetic process GO:0006783 29 15 0,000 0,0841803 0,12722224 ! cell killing GO:0001906 29 15 0,000 0,0841803 0,12714237 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,0841803 0,12706261 ! detection of bacterium GO:0016045 18 15 0,000 0,0841803 0,12698295 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,0841803 0,12690338 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,0841803 0,12682392 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,0841803 0,12674456 ! peptide hormone processing GO:0016486 23 15 0,000 0,0841803 0,12666529 ! regulation of lyase activity GO:0051339 160 83 1,000 0,08503444 0,12787054 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,08678583 0,13042268 ! regulation of transmission of nerve impulse GO:0051969 141 84 1,000 0,08678583 0,13034126 ! response to unfolded protein GO:0006986 131 85 1,000 0,08854805 0,13290493 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,08854805 0,13282208 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,08854805 0,13273932 GO:0002696|positive regulation of leukocyte activation, ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,0895349 0,1341351 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,0895349 0,13405163 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,0895349 0,13396827 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,0895349 0,13388501 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,0895349 0,13380185 ! bone remodeling GO:0046849 27 16 0,000 0,0895349 0,13371879 ! filopodium assembly GO:0046847 32 16 0,000 0,0895349 0,13363584 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,0895349 0,13355299 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,0895349 0,13347025 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,0895349 0,1333876 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,0895349 0,13330506 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,0895349 0,13322262 ! startle response GO:0001964 28 16 0,000 0,0895349 0,13314028 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,0895349 0,13305805 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,0895349 0,13297591 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,0895349 0,13289388 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,0895349 0,13281195 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,0895349 0,13273012 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,0895349 0,13264838 ! protein polyubiquitination GO:0000209 34 16 0,000 0,0895349 0,13256676 ! glutamate metabolic process GO:0006536 22 16 0,000 0,0895349 0,13248523 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,0895349 0,1324038 ! response to osmotic stress GO:0006970 25 16 0,000 0,0895349 0,13232247 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,0895349 0,13224124 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,0895349 0,13216011 ! fructose metabolic process GO:0006000 25 16 0,000 0,0895349 0,13207908 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,0895349 0,13199815 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,0895349 0,13191732 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,0895349 0,13183658 ! negative regulation of immune response GO:0050777 35 16 0,000 0,0895349 0,13175595 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,0895349 0,13167541 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,0895349 0,13159498 ! DNA replication initiation GO:0006270 27 16 0,000 0,0895349 0,13151464 ! neuron recognition GO:0008038 35 16 0,000 0,0895349 0,1314344 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,0895349 0,13135425 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,0895349 0,13127421 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,0895349 0,13119426 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,0895349 0,13111441 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,0895349 0,13103466 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,0895349 0,130955 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,0895349 0,13087544 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,0895349 0,13079598 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,0895349 0,13071661 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,0895349 0,13063734 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,0895349 0,13055817 ! defense response to virus GO:0051607 37 16 0,000 0,0895349 0,13047909 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,09210425 0,13414215 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! gland development GO:0048732 206 88 1,000 0,09389787 0,13667167 ! regulation of neurological system process GO:0031644 148 88 1,000 0,09389787 0,13658904 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,09485838 0,13790287 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,09485838 0,1378196 ! metencephalon development GO:0022037 30 17 0,000 0,09485838 0,13773642 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,09485838 0,13765335 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,09485838 0,13757038 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,09485838 0,1374875 ! endothelial cell migration GO:0043542 28 17 0,000 0,09485838 0,13740473 ! inositol metabolic process GO:0006020 28 17 0,000 0,09485838 0,13732205 ! gene silencing by RNA GO:0031047 36 17 0,000 0,09485838 0,13723948 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,09485838 0,137157 ! glial cell development GO:0021782 27 17 0,000 0,09485838 0,13707463 ! limbic system development GO:0021761 36 17 0,000 0,09485838 0,13699235 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,09485838 0,13691017 ! adult walking behavior GO:0007628 33 17 0,000 0,09485838 0,13682809 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,09485838 0,13674611 ! heart looping GO:0001947 30 17 0,000 0,09485838 0,13666422 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,09485838 0,13658244 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,09485838 0,13650075 ! myoblast differentiation GO:0045445 45 17 0,000 0,09485838 0,13641916 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,09485838 0,13633767 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,09485838 0,13625627 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,09485838 0,13617497 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,09485838 0,13609377 ! glycine metabolic process GO:0006544 28 17 0,000 0,09485838 0,13601267 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,09485838 0,13593166 ! NAD metabolic process GO:0019674 29 17 0,000 0,09485838 0,13585075 ! membrane budding GO:0006900 37 17 0,000 0,09485838 0,13576993 ! DNA integration GO:0015074 29 17 0,000 0,09485838 0,13568921 ! regulation of protein binding GO:0043393 33 17 0,000 0,09485838 0,13560859 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,09485838 0,13552806 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,09485838 0,13544763 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,09485838 0,13536729 ! genitalia development GO:0048806 30 17 0,000 0,09485838 0,13528705 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,09485838 0,1352069 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,09485838 0,13512685 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,09485838 0,1350469 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,09485838 0,13496703 ! steroid catabolic process GO:0006706 31 17 0,000 0,09485838 0,13488727 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,09485838 0,13480759 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,09485838 0,13472801 ! gas transport GO:0015669 25 17 0,000 0,09485838 0,13464853 ! organic cation transport GO:0015695 31 17 0,000 0,09485838 0,13456913 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,09485838 0,13448984 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,09485838 0,13441063 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,09485838 0,13433152 ! microspike assembly GO:0030035 36 17 0,000 0,09485838 0,1342525 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,09485838 0,13417358 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,09485838 0,13409474 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,09751523 0,13776961 ! sterol metabolic process GO:0016125 152 91 1,000 0,09933863 0,14026334 ! response to protein stimulus GO:0051789 149 91 1,000 0,09933863 0,14018108 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,1001509 0,14124447 ! neuron maturation GO:0042551 42 18 0,000 0,1001509 0,14116172 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,1001509 0,14107908 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,1001509 0,14099653 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,1001509 0,14091407 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,1001509 0,14083171 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,1001509 0,14074945 ! memory GO:0007613 31 18 0,000 0,1001509 0,14066729 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,1001509 0,14058522 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,1001509 0,14050324 ! patterning of blood vessels GO:0001569 39 18 0,000 0,1001509 0,14042136 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,1001509 0,14033958 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,1001509 0,14025789 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,1001509 0,1401763 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,1001509 0,1400948 ! glutamine metabolic process GO:0006541 29 18 0,000 0,1001509 0,1400134 ! response to retinoic acid GO:0032526 26 18 0,000 0,1001509 0,13993209 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,1001509 0,13985088 ! response to fungus GO:0009620 21 18 0,000 0,1001509 0,13976976 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,1001509 0,13968873 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,1001509 0,1396078 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,1001509 0,13952696 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,1001509 0,13944622 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,1001509 0,13936556 ! vitamin transport GO:0051180 27 18 0,000 0,1001509 0,13928501 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,1001509 0,13920454 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,1001509 0,13912417 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,1001509 0,13904389 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,1001509 0,1389637 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,1001509 0,13888361 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,1001509 0,13880361 ! nerve development GO:0021675 28 18 0,000 0,1001509 0,1387237 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,1001509 0,13864388 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 1,000 0,10301397 0,14252537 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,10301397 0,14244346 ! regulation of membrane potential GO:0042391 164 93 1,000 0,10301397 0,14236164 ! transcription initiation GO:0006352 153 94 1,000 0,10486558 0,14483731 ! protein secretion GO:0009306 39 19 0,000 0,10541265 0,14550937 ! positive regulation of translation GO:0045727 30 19 0,000 0,10541265 0,14542594 ! negative regulation of defense response GO:0031348 25 19 0,000 0,10541265 0,1453426 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,10541265 0,14525936 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,10541265 0,14517621 ! skin development GO:0043588 36 19 0,000 0,10541265 0,14509315 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,10541265 0,1450102 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,10541265 0,14492733 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,10541265 0,14484457 ! bile acid metabolic process GO:0008206 29 19 0,000 0,10541265 0,14476189 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,10541265 0,14467931 ! cerebral cortex development GO:0021987 36 19 0,000 0,10541265 0,14459683 ! pigmentation during development GO:0048066 41 19 0,000 0,10541265 0,14451444 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,10541265 0,14443214 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,10541265 0,14434993 ! heme metabolic process GO:0042168 36 19 0,000 0,10541265 0,14426782 ! actin filament bundle formation GO:0051017 42 19 0,000 0,10541265 0,14418581 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,10541265 0,14410388 ! plasma membrane fusion GO:0045026 28 19 0,000 0,10541265 0,14402205 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,10541265 0,14394031 ! peptide cross-linking GO:0018149 37 19 0,000 0,10541265 0,14385867 ! protein export from nucleus GO:0006611 36 19 0,000 0,10541265 0,14377712 ! heart process GO:0003015 30 19 0,000 0,10541265 0,14369566 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,10541265 0,14361429 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,10541265 0,14353301 ! visual learning GO:0008542 36 19 0,000 0,10541265 0,14345183 ! cellular pigmentation GO:0033059 36 19 0,000 0,10541265 0,14337074 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,10541265 0,14328974 ! cell-cell junction organization GO:0045216 35 19 0,000 0,10541265 0,14320883 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,10541265 0,14312801 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,10541265 0,14304728 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,10541265 0,14296665 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,10541265 0,1428861 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,10541265 0,14280565 ! cilium assembly GO:0042384 37 19 0,000 0,10541265 0,14272529 ! peptide hormone secretion GO:0030072 31 19 0,000 0,10541265 0,14264501 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,10672625 0,14434141 ! detection of stimulus GO:0051606 151 96 1,000 0,10859582 0,14678738 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,11064381 0,14947164 ! positive regulation of ossification GO:0045778 47 20 0,000 0,11064381 0,14938777 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,11064381 0,14930398 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,11064381 0,14922029 ! cAMP metabolic process GO:0046058 36 20 0,000 0,11064381 0,14913669 ! response to vitamin GO:0033273 31 20 0,000 0,11064381 0,14905319 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,11064381 0,14896978 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,11064381 0,14888646 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,11064381 0,14880324 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,11064381 0,14872011 ! retinoid metabolic process GO:0001523 32 20 0,000 0,11064381 0,14863707 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,11064381 0,14855413 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,11064381 0,14847128 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,11064381 0,14838852 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,11064381 0,14830585 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,11064381 0,14822327 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,11064381 0,14814079 ! body fluid secretion GO:0007589 31 20 0,000 0,11064381 0,1480584 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,11064381 0,1479761 ! peptide secretion GO:0002790 35 20 0,000 0,11064381 0,14789389 ! stem cell differentiation GO:0048863 53 20 0,000 0,11064381 0,14781177 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,11064381 0,14772974 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,11064381 0,14764781 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,11064381 0,14756596 ! sensory perception of pain GO:0019233 30 20 0,000 0,11064381 0,14748421 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,11064381 0,14740255 ! diencephalon development GO:0021536 34 20 0,000 0,11064381 0,14732097 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,11064381 0,14723949 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,11064381 0,1471581 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,11064381 0,1470768 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,11064381 0,14699558 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,11064381 0,14691446 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,11064381 0,14683342 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,11064381 0,14675248 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,11064381 0,14667162 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,11064381 0,14659086 ! actin filament-based movement GO:0030048 43 20 0,000 0,11064381 0,14651018 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,11064381 0,14642959 ! negative regulation of translation GO:0017148 29 20 0,000 0,11064381 0,14634909 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,11064381 0,14626868 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,11064381 0,14618836 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,11425624 0,15087844 ! regulation of cell killing GO:0031341 42 21 0,000 0,11584455 0,15289193 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,11584455 0,1528081 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,11584455 0,15272437 ! hormone secretion GO:0046879 38 21 0,000 0,11584455 0,15264073 ! glycerol metabolic process GO:0006071 34 21 0,000 0,11584455 0,15255719 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,11584455 0,15247373 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,11584455 0,15239037 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,11584455 0,15230709 ! axis specification GO:0009798 38 21 0,000 0,11584455 0,15222391 ! ovarian follicle development GO:0001541 35 21 0,000 0,11584455 0,15214082 ! smooth muscle contraction GO:0006939 46 21 0,000 0,11584455 0,15205782 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,11584455 0,15197491 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,11584455 0,15189209 ! cell aging GO:0007569 44 21 0,000 0,11584455 0,15180936 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,11584455 0,15172672 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,11584455 0,15164417 ! cytolysis GO:0019835 24 21 0,000 0,11584455 0,15156171 ! vasodilation GO:0042311 39 21 0,000 0,11584455 0,15147934 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,11584455 0,15139706 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,11584455 0,15131486 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,11584455 0,15123276 ! oogenesis GO:0048477 36 21 0,000 0,11584455 0,15115075 ! DNA modification GO:0006304 34 21 0,000 0,11584455 0,15106882 ! collagen fibril organization GO:0030199 59 21 0,000 0,11584455 0,15098699 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,11584455 0,15090524 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,11584455 0,15082358 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,11584455 0,15074201 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,11584455 0,15066053 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,11584455 0,15057914 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,11584455 0,15049783 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,11584455 0,15041661 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,11584455 0,15033548 ! collagen catabolic process GO:0030574 28 21 0,000 0,11584455 0,15025444 ! sperm-egg recognition GO:0035036 21 21 0,000 0,11584455 0,15017348 ! gut development GO:0048565 39 21 0,000 0,11584455 0,15009261 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,12101505 0,15670732 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,12101505 0,15662302 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,12101505 0,15653882 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,12101505 0,1564547 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,12101505 0,15637068 GO:0034105|positive regulation of tissue remodeling, ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,12101505 0,15628674 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,12101505 0,1562029 ! regeneration GO:0031099 41 22 0,000 0,12101505 0,15611914 ! keratinization GO:0031424 28 22 0,000 0,12101505 0,15603548 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,12101505 0,1559519 ! sensory perception of taste GO:0050909 28 22 0,000 0,12101505 0,15586842 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,12101505 0,15578502 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,12101505 0,15570171 ! vacuolar transport GO:0007034 36 22 0,000 0,12101505 0,15561849 ! lysosome organization GO:0007040 41 22 0,000 0,12101505 0,15553537 ! central nervous system neuron development GO:0021954 46 22 0,000 0,12101505 0,15545232 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,12101505 0,15536937 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,12101505 0,15528651 ! fucose metabolic process GO:0006004 39 22 0,000 0,12101505 0,15520373 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,12101505 0,15512105 ! ureteric bud development GO:0001657 43 22 0,000 0,12101505 0,15503845 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,12101505 0,15495594 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,12101505 0,15487351 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,12101505 0,15479118 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,12101505 0,15470893 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,12101505 0,15462677 ! sarcomere organization GO:0045214 30 22 0,000 0,12101505 0,15454469 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,12101505 0,15446271 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,12101505 0,15438081 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,12101505 0,15429899 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,12615548 0,16076805 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,12615548 0,16068295 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,12615548 0,16059793 ! gluconeogenesis GO:0006094 33 23 0,000 0,12615548 0,160513 ! viral genome replication GO:0019079 41 23 0,000 0,12615548 0,16042816 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,12615548 0,16034342 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,12615548 0,16025876 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,12615548 0,16017419 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,12615548 0,16008971 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,12615548 0,16000532 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,12615548 0,15992102 ! visual behavior GO:0007632 42 23 0,000 0,12615548 0,1598368 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,12615548 0,15975268 ! response to ethanol GO:0045471 46 23 0,000 0,12615548 0,15966864 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,12615548 0,15958469 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,12615548 0,15950083 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,12615548 0,15941706 ! vesicle targeting GO:0006903 43 23 0,000 0,12615548 0,15933338 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,12615548 0,15924978 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,12615548 0,15916628 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,12615548 0,15908285 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,12615548 0,15899952 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,12615548 0,15891628 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,12615548 0,15883312 ! fatty acid transport GO:0015908 44 23 0,000 0,12615548 0,15875005 ! platelet activation GO:0030168 37 23 0,000 0,12615548 0,15866706 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,12615548 0,15858416 ! hormone transport GO:0009914 40 23 0,000 0,12615548 0,15850135 ! cell-cell recognition GO:0009988 25 23 0,000 0,12615548 0,15841863 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,12615548 0,15833599 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,12615548 0,15825343 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,12615548 0,15817097 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,12615548 0,15808859 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,13126602 0,16440711 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,13126602 0,16432157 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,13126602 0,16423612 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,13126602 0,16415075 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,13126602 0,16406548 ! vesicle docking GO:0048278 47 24 0,000 0,13126602 0,1639803 ! spinal cord development GO:0021510 47 24 0,000 0,13126602 0,1638952 ! vacuole organization GO:0007033 43 24 0,000 0,13126602 0,16381019 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,13126602 0,16372527 ! digestive system process GO:0022600 39 24 0,000 0,13126602 0,16364044 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,13126602 0,1635557 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,13126602 0,16347104 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,13126602 0,16338647 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,13126602 0,16330199 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,13126602 0,1632176 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,13126602 0,16313329 ! membrane depolarization GO:0051899 39 24 0,000 0,13126602 0,16304907 ! pallium development GO:0021543 49 24 0,000 0,13126602 0,16296494 ! pentose metabolic process GO:0019321 35 24 0,000 0,13126602 0,16288089 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,13126602 0,16279693 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,13126602 0,16271306 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,13126602 0,16262927 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,13126602 0,16254557 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,13126602 0,16246196 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,13126602 0,16237843 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,13126602 0,16229499 ! regulation of amine transport GO:0051952 40 24 0,000 0,13126602 0,16221163 ! protein tetramerization GO:0051262 52 24 0,000 0,13126602 0,16212836 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,13634684 0,16831735 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,13634684 0,16823103 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,13634684 0,1681448 ! phototransduction GO:0007602 33 25 0,000 0,13634684 0,16805866 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,13634684 0,16797261 ! sperm motility GO:0030317 31 25 0,000 0,13634684 0,16788665 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,13634684 0,16780077 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,13634684 0,16771498 ! chromosome condensation GO:0030261 45 25 0,000 0,13634684 0,16762928 ! osteoblast differentiation GO:0001649 60 25 0,000 0,13634684 0,16754367 ! neural crest cell development GO:0014032 54 25 0,000 0,13634684 0,16745815 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,13634684 0,16737271 ! negative regulation of cell development GO:0010721 73 25 0,000 0,13634684 0,16728736 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,13634684 0,16720209 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,13634684 0,16711692 ! interaction with host GO:0051701 62 25 0,000 0,13634684 0,16703183 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,13634684 0,16694682 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,13634684 0,16686191 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,13634684 0,16677708 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,13634684 0,16669233 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,13634684 0,16660767 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,13634684 0,1665231 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,13634684 0,16643861 ! telomere organization GO:0032200 43 25 0,000 0,13634684 0,16635421 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,13634684 0,1662699 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,13634684 0,16618567 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,14139812 0,17225513 ! embryonic pattern specification GO:0009880 44 26 0,000 0,14139812 0,17216795 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,14139812 0,17208087 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,14139812 0,17199387 ! initiation of viral infection GO:0019059 57 26 0,000 0,14139812 0,17190696 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,14139812 0,17182014 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,14139812 0,1717334 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,14139812 0,17164676 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,14139812 0,1715602 ! molting cycle process GO:0022404 50 26 0,000 0,14139812 0,17147373 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,14139812 0,17138734 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,14139812 0,17130104 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,14139812 0,17121483 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,14139812 0,17112871 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,14139812 0,17104267 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,14139812 0,17095672 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,14139812 0,17087086 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,14139812 0,17078508 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,14139812 0,17069938 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,14139812 0,17061378 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,14139812 0,17052826 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,14139812 0,17044282 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,14139812 0,17035747 ! blastocyst development GO:0001824 49 26 0,000 0,14139812 0,17027221 ! leukocyte proliferation GO:0070661 52 26 0,000 0,14139812 0,17018703 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,14139812 0,17010194 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,14139812 0,17001693 ! neuron fate commitment GO:0048663 48 27 0,000 0,14642002 0,17596731 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,14642002 0,17587946 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,14642002 0,1757917 ! iron ion transport GO:0006826 59 27 0,000 0,14642002 0,17570402 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,14642002 0,17561643 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,14642002 0,17552893 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,14642002 0,17544151 ! fat cell differentiation GO:0045444 50 27 0,000 0,14642002 0,17535419 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,14642002 0,17526695 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,14642002 0,17517979 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,14642002 0,17509272 ! autophagy GO:0006914 41 27 0,000 0,14642002 0,17500574 ! response to toxin GO:0009636 47 27 0,000 0,14642002 0,17491885 ! primary neural tube formation GO:0014020 51 27 0,000 0,14642002 0,17483204 ! base-excision repair GO:0006284 41 27 0,000 0,14642002 0,17474532 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,14642002 0,17465868 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,14642002 0,17457213 ! glutathione metabolic process GO:0006749 39 27 0,000 0,14642002 0,17448567 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,14642002 0,17439929 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,14642002 0,17431299 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,14642002 0,17422679 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,15141271 0,18007858 ! circadian rhythm GO:0007623 50 28 0,000 0,15141271 0,17998961 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,15141271 0,17990073 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,15141271 0,17981193 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,15141271 0,17972322 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,15141271 0,1796346 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,15141271 0,17954607 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,15141271 0,17945762 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,15141271 0,17936926 ! synaptogenesis GO:0007416 42 28 0,000 0,15141271 0,17928099 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,15141271 0,17919281 ! lipid oxidation GO:0034440 43 28 0,000 0,15141271 0,17910471 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,15141271 0,1790167 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,15141271 0,17892877 ! translational initiation GO:0006413 65 29 0,000 0,15637636 0,18470374 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,15637636 0,18461311 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,15637636 0,18452257 ! regulation of pH GO:0006885 43 29 0,000 0,15637636 0,18443212 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,15637636 0,18434176 ! catechol metabolic process GO:0009712 54 29 0,000 0,15637636 0,18425148 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,15637636 0,18416129 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,15637636 0,1840712 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,15637636 0,18398119 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,15637636 0,18389126 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,15637636 0,18380143 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,15637636 0,18371168 ! cell fate determination GO:0001709 60 29 0,000 0,15637636 0,18362202 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,15637636 0,18353245 ! detection of light stimulus GO:0009583 38 29 0,000 0,15637636 0,18344297 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,15637636 0,18335357 ! tissue homeostasis GO:0001894 48 29 0,000 0,15637636 0,18326426 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,15637636 0,18317504 ! phenol metabolic process GO:0018958 55 30 0,000 0,16131114 0,18886356 ! zinc ion transport GO:0006829 45 30 0,000 0,16131114 0,1887717 ! membrane docking GO:0022406 61 30 0,000 0,16131114 0,18867993 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,16131114 0,18858825 ! cell junction assembly GO:0034329 78 30 0,000 0,16131114 0,18849666 ! regulation of innate immune response GO:0045088 51 30 0,000 0,16131114 0,18840515 ! acute-phase response GO:0006953 49 30 0,000 0,16131114 0,18831374 ! myofibril assembly GO:0030239 47 30 0,000 0,16131114 0,18822241 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,16131114 0,18813118 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,16131114 0,18804003 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,16131114 0,18794897 ! phospholipid transport GO:0015914 51 30 0,000 0,16131114 0,18785799 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,16131114 0,18776711 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,16131114 0,18767631 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,16131114 0,1875856 ! eye morphogenesis GO:0048592 60 30 0,000 0,16131114 0,18749498 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,16621723 0,19310413 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,16621723 0,19301093 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,16621723 0,19291782 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,16621723 0,1928248 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,16621723 0,19273188 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,16621723 0,19263904 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,16621723 0,19254629 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,16621723 0,19245363 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,16621723 0,19236106 ! ovulation cycle process GO:0022602 49 31 0,000 0,16621723 0,19226858 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,16621723 0,19217619 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,16621723 0,19208388 ! peptide transport GO:0015833 55 31 0,000 0,16621723 0,19199167 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,16621723 0,19189954 ! mesoderm formation GO:0001707 69 31 0,000 0,16621723 0,1918075 ! natural killer cell activation GO:0030101 45 31 0,000 0,16621723 0,19171555 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,16621723 0,19162369 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,16621723 0,19153192 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,16621723 0,19144023 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,16621723 0,19134863 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,17109477 0,19686945 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,17109477 0,19677534 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,17109477 0,19668132 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,17109477 0,1965874 ! cholesterol transport GO:0030301 56 32 0,000 0,17109477 0,19649356 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,17109477 0,19639982 ! spliceosome assembly GO:0000245 67 32 0,000 0,17109477 0,19630616 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,17109477 0,19621259 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,17109477 0,19611911 ! response to ionizing radiation GO:0010212 65 32 0,000 0,17109477 0,19602572 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,17109477 0,19593242 ! muscle cell development GO:0055001 49 32 0,000 0,17109477 0,19583921 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,17109477 0,19574608 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,17109477 0,19565305 ! ovulation cycle GO:0042698 51 32 0,000 0,17109477 0,1955601 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,17109477 0,19546724 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,17109477 0,19537447 ! positive regulation of catabolic process GO:0009896 64 32 0,000 0,17109477 0,19528179 ! gene silencing GO:0016458 65 32 0,000 0,17109477 0,1951892 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,17594394 0,20062612 ! post-embryonic development GO:0009791 69 33 0,000 0,17594394 0,20053108 ! protein targeting to membrane GO:0006612 68 33 0,000 0,17594394 0,20043614 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,17594394 0,20034128 ! ceramide metabolic process GO:0006672 64 33 0,000 0,17594394 0,20024651 ! formation of primary germ layer GO:0001704 72 33 0,000 0,17594394 0,20015183 ! sterol transport GO:0015918 57 33 0,000 0,17594394 0,20005724 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,17594394 0,19996274 ! adult locomotory behavior GO:0008344 59 33 0,000 0,17594394 0,19986833 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,17594394 0,19977401 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,1807649 0,20515111 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,1807649 0,20505439 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,1807649 0,20495776 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,1807649 0,20486121 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,1807649 0,20476476 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,1807649 0,2046684 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,1807649 0,20457213 ! mismatch repair GO:0006298 46 34 0,000 0,1807649 0,20447596 ! spermatid development GO:0007286 63 34 0,000 0,1807649 0,20437987 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,1807649 0,20428387 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,1807649 0,20418796 ! placenta development GO:0001890 53 34 0,000 0,1807649 0,20409214 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,1807649 0,20399642 ! regulation of muscle development GO:0048634 70 35 0,000 0,18555782 0,20930714 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,18555782 0,20920905 ! negative regulation of secretion GO:0051048 63 35 0,000 0,18555782 0,20911106 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,18555782 0,20901316 ! odontogenesis GO:0042476 66 35 0,000 0,18555782 0,20891536 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,18555782 0,20881764 ! female gonad development GO:0008585 58 35 0,000 0,18555782 0,20872002 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,18555782 0,20862249 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,18555782 0,20852504 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,18555782 0,20842769 ! cytokine production GO:0001816 59 35 0,000 0,18555782 0,20833043 ! neural tube formation GO:0001841 67 35 0,000 0,18555782 0,20823326 ! vesicle localization GO:0051648 64 35 0,000 0,18555782 0,20813619 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,19032286 0,21338155 ! cell junction organization GO:0034330 86 36 0,000 0,19032286 0,21328216 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,19032286 0,21318287 ! positive regulation of cell development GO:0010720 80 36 0,000 0,19032286 0,21308367 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,19032286 0,21298456 ! regulation of proteolysis GO:0030162 72 36 0,000 0,19032286 0,21288554 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,19032286 0,21278662 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,19032286 0,21268778 ! aerobic respiration GO:0009060 55 36 0,000 0,19032286 0,21258904 ! embryonic organ development GO:0048568 57 36 0,000 0,19032286 0,21249039 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,19032286 0,21239184 ! RNA export from nucleus GO:0006405 56 37 0,000 0,19506017 0,21757755 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,19506017 0,21747673 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,19506017 0,217376 ! actomyosin structure organization GO:0031032 62 37 0,000 0,19506017 0,21727536 ! organic anion transport GO:0015711 68 37 0,000 0,19506017 0,21717482 ! tissue remodeling GO:0048771 76 37 0,000 0,19506017 0,21707437 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,19506017 0,21697401 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,19506017 0,21687374 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,19506017 0,21677357 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,19506017 0,21667349 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,19506017 0,2165735 ! spermatid differentiation GO:0048515 66 37 0,000 0,19506017 0,21647361 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,19976993 0,22159818 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,19976993 0,22149606 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,19976993 0,22139403 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,19976993 0,2212921 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,19976993 0,22119027 GO:0046660|female sex differentiation, ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,19976993 0,22108852 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,19976993 0,22098687 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,19976993 0,22088532 ! mRNA catabolic process GO:0006402 71 39 0,000 0,20445228 0,22595874 ! organic ether metabolic process GO:0018904 55 39 0,000 0,20445228 0,225855 ! ion transmembrane transport GO:0034220 66 39 0,000 0,20445228 0,22575135 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,20445228 0,22564779 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,20445228 0,22554433 ! RNA modification GO:0009451 57 39 0,000 0,20445228 0,22544097 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,20445228 0,22533769 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,20910739 0,23036281 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,20910739 0,23025738 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,20910739 0,23015205 ! feeding behavior GO:0007631 59 40 0,000 0,20910739 0,23004681 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,20910739 0,22994167 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,21373542 0,23492344 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,21373542 0,23481617 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,21373542 0,234709 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,21373542 0,23460192 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,21373542 0,23449494 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,21373542 0,23438806 ! female gamete generation GO:0007292 61 41 0,000 0,21373542 0,23428128 ! polyol metabolic process GO:0019751 66 41 0,000 0,21373542 0,23417459 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,21373542 0,23406801 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,21833651 0,23899802 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,21833651 0,23888933 ! regulation of tube size GO:0035150 71 42 0,000 0,21833651 0,23878075 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,21833651 0,23867226 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,21833651 0,23856387 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,21833651 0,23845558 ! neuron migration GO:0001764 79 42 0,000 0,21833651 0,23834739 ! regulation of protein secretion GO:0050708 71 42 0,000 0,21833651 0,2382393 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,22291083 0,24312034 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,22291083 0,24301018 ! glucose transport GO:0015758 65 43 0,000 0,22291083 0,24290012 ! neural tube development GO:0021915 77 43 0,000 0,22291083 0,24279016 ! striated muscle contraction GO:0006941 77 43 0,000 0,22291083 0,2426803 ! phagocytosis GO:0006909 90 43 0,000 0,22291083 0,24257054 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,22291083 0,24246088 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,22745854 0,24729564 ! hexose transport GO:0008645 67 44 0,000 0,22745854 0,24718394 GO:0015749|monosaccharide transport, ! double-strand break repair GO:0006302 81 44 0,000 0,22745854 0,24707235 ! B cell differentiation GO:0030183 107 44 0,000 0,22745854 0,24696085 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,22745854 0,24684946 ! developmental growth GO:0048589 82 44 0,000 0,22745854 0,24673816 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,23197978 0,25152923 ! glycolysis GO:0006096 65 45 0,000 0,23197978 0,25141593 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,23197978 0,25130273 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,23197978 0,25118963 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,23197978 0,25107663 ! icosanoid metabolic process GO:0006690 80 45 0,000 0,23197978 0,25096374 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,23197978 0,25085095 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,23647471 0,25559666 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,23647471 0,25548189 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,23647471 0,25536722 ! response to calcium ion GO:0051592 81 47 0,000 0,24094348 0,26007628 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,24094348 0,25995965 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,24094348 0,25984313 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,24094348 0,25972671 ! JNK cascade GO:0007254 91 47 0,000 0,24094348 0,2596104 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,24094348 0,25949419 ! protein homooligomerization GO:0051260 76 47 0,000 0,24094348 0,25937809 ! mitochondrial transport GO:0006839 82 48 0,000 0,24538625 0,26404263 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,24538625 0,26392459 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,24538625 0,26380667 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,24538625 0,26368884 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,24980316 0,26831536 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,24980316 0,26819563 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,24980316 0,268076 ! regulation of ion transport GO:0043269 77 49 0,000 0,24980316 0,26795649 ! peptide metabolic process GO:0006518 76 49 0,000 0,24980316 0,26783708 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,24980316 0,26771777 ! endocrine system development GO:0035270 104 49 0,000 0,24980316 0,26759857 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,24980316 0,26747948 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,24980316 0,2673605 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,24980316 0,26724162 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,25419436 0,2718185 ! neuromuscular process GO:0050905 99 50 0,000 0,25419436 0,27169775 ! regulation of ossification GO:0030278 117 50 0,000 0,25419436 0,2715771 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,25419436 0,27145656 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,25419436 0,27133613 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,25856 0,27587378 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,25856 0,27575149 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,25856 0,27562932 ! excretion GO:0007588 83 51 0,000 0,25856 0,27550725 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,25856 0,27538529 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,25856 0,27526344 ! regulation of cell shape GO:0008360 125 51 0,000 0,25856 0,27514169 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,25856 0,27502006 ! membrane fusion GO:0006944 110 52 0,000 0,26290024 0,27951302 ! positive regulation of growth GO:0045927 90 52 0,000 0,26290024 0,27938956 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,26290024 0,27926621 ! amino acid activation GO:0043038 92 52 0,000 0,26290024 0,27914297 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! RNA catabolic process GO:0006401 93 53 0,000 0,26721521 0,28359938 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,26721521 0,28347433 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,26721521 0,2833494 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,26721521 0,28322457 ! cell maturation GO:0048469 100 53 0,000 0,26721521 0,28309986 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,26721521 0,28297526 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,26721521 0,28285076 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,27150506 0,28726525 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,27150506 0,28713898 ! cell recognition GO:0008037 85 54 0,000 0,27150506 0,28701282 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,27150506 0,28688677 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,27150506 0,28676083 ! glucose catabolic process GO:0006007 82 55 0,000 0,27576994 0,29113755 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,27576994 0,29100986 ! gastrulation GO:0007369 112 55 0,000 0,27576994 0,29088228 ! heart morphogenesis GO:0003007 97 55 0,000 0,27576994 0,29075481 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,27576994 0,29062745 ! RNA elongation GO:0006354 79 55 0,000 0,27576994 0,29050021 ! nuclear export GO:0051168 97 55 0,000 0,27576994 0,29037307 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,27576994 0,29024605 ! regulation of actin filament length GO:0030832 105 56 0,000 0,28000999 0,29457982 ! sensory perception of smell GO:0007608 80 56 0,000 0,28000999 0,29445107 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,28000999 0,29432243 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,28000999 0,2941939 ! proton transport GO:0015992 94 56 0,000 0,28000999 0,29406549 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,28422536 0,29836223 ! hydrogen transport GO:0006818 97 58 0,000 0,28841619 0,30262946 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,28841619 0,30249754 ! regulation of endocytosis GO:0030100 91 58 0,000 0,28841619 0,30236573 ! adult behavior GO:0030534 99 58 0,000 0,28841619 0,30223404 ! positive regulation of secretion GO:0051047 95 59 0,000 0,29258262 0,3064666 ! regulation of cellular component size GO:0032535 109 59 0,000 0,29258262 0,30633324 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,29258262 0,3062 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,29258262 0,30606687 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,2967248 0,31026504 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,2967248 0,31013026 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,30084285 0,31429783 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,30084285 0,31416142 ! mesoderm development GO:0007498 119 61 0,000 0,30084285 0,31402512 ! tRNA processing GO:0008033 89 61 0,000 0,30084285 0,31388894 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,30084285 0,31375288 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,30493693 0,31788486 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,30900717 0,32198842 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,30900717 0,32184903 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,31305372 0,32592265 ! cell redox homeostasis GO:0045454 102 64 0,000 0,31305372 0,32578168 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,31305372 0,32564083 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,31305372 0,3255001 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,31305372 0,3253595 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,31707669 0,32939833 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,31707669 0,32925616 GO:0035113|embryonic appendage morphogenesis, ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,32107624 0,33326551 ! extracellular matrix organization GO:0030198 133 66 0,000 0,32107624 0,33312179 ! secondary metabolic process GO:0019748 116 66 0,000 0,32107624 0,33297821 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,3250525 0,33695662 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,3250525 0,33681151 ! activation of MAPK activity GO:0000187 115 67 0,000 0,3250525 0,33666652 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,3250525 0,33652165 ! hexose catabolic process GO:0019320 104 67 0,000 0,3250525 0,33637691 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,3250525 0,3362323 ! adaptive immune response GO:0002250 119 67 0,000 0,3250525 0,33608781 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,3250525 0,33594344 ! amino acid transport GO:0006865 125 68 0,000 0,32900561 0,33988299 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,32900561 0,33973712 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,32900561 0,33959137 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,33293569 0,34350054 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,33293569 0,34335331 ! antigen processing and presentation GO:0019882 104 69 0,000 0,33293569 0,3432062 ! appendage morphogenesis GO:0035107 135 70 0,000 0,33684288 0,34708521 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,34072732 0,35093747 ! appendage development GO:0048736 136 71 0,000 0,34072732 0,3507873 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,34072732 0,35063726 ! B cell activation GO:0042113 160 71 0,000 0,34072732 0,35048736 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,34072732 0,35033757 ! regulation of immune effector process GO:0002697 137 71 0,000 0,34072732 0,35018792 ! acute inflammatory response GO:0002526 113 72 0,000 0,34458913 0,35400574 ! carbohydrate transport GO:0008643 110 72 0,000 0,34458913 0,35385465 ! regulation of blood pressure GO:0008217 125 73 0,000 0,34842845 0,35764456 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,34842845 0,35749204 ! fertilization GO:0009566 90 73 0,000 0,34842845 0,35733966 ! transition metal ion transport GO:0000041 126 74 0,000 0,3522454 0,36110031 ! neurotransmitter transport GO:0006836 123 74 0,000 0,3522454 0,36094652 ! exocytosis GO:0006887 133 74 0,000 0,3522454 0,36079286 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,3522454 0,36063933 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,3522454 0,36048594 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,35604012 0,36421451 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,35604012 0,36405973 ! rhythmic process GO:0048511 128 75 0,000 0,35604012 0,36390507 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,35981274 0,36760486 ! defense response to bacterium GO:0042742 89 76 0,000 0,35981274 0,36744883 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,35981274 0,36729294 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,35981274 0,36713717 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,36356338 0,3708069 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,36356338 0,37064978 ! blood coagulation GO:0007596 146 78 0,000 0,36729217 0,37429265 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,36729217 0,37413419 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,36729217 0,37397586 ! protein oligomerization GO:0051259 139 78 0,000 0,36729217 0,37381766 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,37099923 0,37743093 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,37099923 0,37727141 ! response to metal ion GO:0010038 140 80 0,000 0,3746847 0,38085822 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,3746847 0,38069738 ! protein import into nucleus GO:0006606 158 80 0,000 0,3746847 0,38053668 ! digestion GO:0007586 112 81 0,000 0,3783487 0,38409577 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,3783487 0,38393377 ! nuclear import GO:0051170 161 81 0,000 0,3783487 0,38377191 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,3783487 0,38361019 ! response to drug GO:0042493 143 82 0,000 0,38199135 0,38714035 ! hemostasis GO:0007599 158 84 0,000 0,3892131 0,39429336 ! nucleosome assembly GO:0006334 122 85 0,000 0,39279245 0,39775195 ! amine biosynthetic process GO:0009309 138 86 0,000 0,39635094 0,40118652 ! response to inorganic substance GO:0010035 153 86 0,000 0,39635094 0,40101781 ! chromatin assembly GO:0031497 124 86 0,000 0,39635094 0,40084924 ! tube morphogenesis GO:0035239 176 86 0,000 0,39635094 0,40068082 ! alcohol catabolic process GO:0046164 130 86 0,000 0,39635094 0,40051254 ! amine transport GO:0015837 155 86 0,000 0,39635094 0,4003444 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,39988869 0,40374829 ! protein localization in nucleus GO:0034504 176 87 0,000 0,39988869 0,40357894 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,40340582 0,40695783 ! cellular defense response GO:0006968 114 89 0,000 0,40690246 0,41031321 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,40690246 0,41014132 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,41037872 0,41347203 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,41383473 0,41677955 ! nucleosome organization GO:0034728 138 92 0,000 0,41727058 0,42006403 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,41727058 0,41988834 ! vitamin metabolic process GO:0006766 139 92 0,000 0,41727058 0,4197128 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,42068642 0,4229718 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,42068642 0,42279512 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,42408234 0,42603011 ! female pregnancy GO:0007565 164 94 0,000 0,42408234 0,4258523 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,43081492 0,4324325 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,43081492 0,43225216 ! positive regulation of immune response GO:0050778 156 96 0,000 0,43081492 0,43207198 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,4341518 0,43523718 ! protein ubiquitination GO:0016567 217 97 0,000 0,4341518 0,43505591 ! hormone metabolic process GO:0042445 157 97 0,000 0,4341518 0,43487478 ! response to virus GO:0009615 160 98 0,000 0,43746923 0,43801539 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,43746923 0,43783318 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,43746923 0,43765113 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,44076732 0,44076732