pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6447-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of phosphorylation GO:0042326 52 24 6,000 4,952E-11 1,21E-07 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 6,000 9,323E-11 1,139E-07 GO:0045936|negative regulation of phosphate metabolic process, ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 6,000 2,181E-10 1,776E-07 ! regulation of epithelial cell proliferation GO:0050678 122 45 6,000 5,878E-09 3,59E-06 ! cellular response to extracellular stimulus GO:0031668 52 31 5,000 1,871E-08 9,142E-06 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 5,000 2,22E-07 9,038E-05 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 3,000 3,051E-07 1,065E-04 ! cellular response to nutrient levels GO:0031669 45 27 4,000 3,82E-07 1,167E-04 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 5,000 8,171E-07 2,218E-04 ! interphase of mitotic cell cycle GO:0051329 224 98 6,000 1,395E-06 3,409E-04 ! cellular response to nutrient GO:0031670 8 5 2,000 1,714E-06 3,808E-04 ! androgen receptor signaling pathway GO:0030521 81 37 4,000 1,971E-06 4,013E-04 ! negative regulation of protein kinase activity GO:0006469 144 69 5,000 2,553E-06 4,798E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 5,000 2,553E-06 4,455E-04 ! negative regulation of kinase activity GO:0033673 145 70 5,000 2,779E-06 4,527E-04 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 3,000 3,459E-06 5,282E-04 ! negative regulation of transferase activity GO:0051348 155 74 5,000 3,855E-06 5,539E-04 ! induction of apoptosis by intracellular signals GO:0008629 95 45 4,000 5,327E-06 7,23E-04 ! positive regulation of protein ubiquitination GO:0031398 14 7 2,000 5,951E-06 7,652E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 2,000 5,951E-06 7,269E-04 ! positive regulation of phosphorylation GO:0042327 149 81 5,000 6,537E-06 7,605E-04 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 5,000 7,532E-06 8,364E-04 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of epithelial cell proliferation GO:0050679 73 24 3,000 9,278E-06 9,855E-04 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 9,482E-06 9,652E-04 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 9,482E-06 9,266E-04 ! vasculogenesis GO:0001570 49 25 3,000 1,1E-05 1,033E-03 ! induction of positive chemotaxis GO:0050930 17 9 2,000 1,416E-05 1,282E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 2,000 2,015E-05 1,758E-03 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 2,000 2,015E-05 1,698E-03 ! induction of an organ GO:0001759 17 10 2,000 2,015E-05 1,641E-03 ! chondrocyte differentiation GO:0002062 27 11 2,000 2,759E-05 2,175E-03 ! negative regulation of glucose import GO:0046325 18 11 2,000 2,759E-05 2,107E-03 GO:0010829|negative regulation of glucose transport, ! steroid hormone receptor signaling pathway GO:0030518 146 66 4,000 3,543E-05 2,623E-03 ! regulation of B cell proliferation GO:0030888 22 12 2,000 3,664E-05 2,633E-03 ! regulation of positive chemotaxis GO:0050926 22 12 2,000 3,664E-05 2,558E-03 GO:0050927|positive regulation of positive chemotaxis, ! negative regulation of mast cell proliferation GO:0070667 24 12 2,000 3,664E-05 2,486E-03 GO:0042130|negative regulation of T cell proliferation, ! developmental induction GO:0031128 22 12 2,000 3,664E-05 2,419E-03 GO:0045168|cell-cell signaling involved in cell fate specification, ! negative regulation of cell growth GO:0030308 142 67 4,000 3,811E-05 2,45E-03 ! negative regulation of cell size GO:0045792 144 69 4,000 4,395E-05 2,753E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 4,000 5,046E-05 3,082E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 2,000 6,012E-05 3,583E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 4,000 6,159E-05 3,582E-03 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 7,485E-05 4,252E-03 ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 7,485E-05 4,156E-03 ! regulation of protein ubiquitination GO:0031396 28 16 2,000 9,174E-05 4,98E-03 ! axon cargo transport GO:0008088 46 16 2,000 9,174E-05 4,872E-03 ! negative regulation of leukocyte proliferation GO:0070664 32 16 2,000 9,174E-05 4,768E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! DNA fragmentation involved in apoptosis GO:0006309 27 17 2,000 1,109E-04 5,646E-03 ! neutrophil chemotaxis GO:0030593 29 17 2,000 1,109E-04 5,531E-03 ! negative regulation of growth GO:0045926 168 85 4,000 1,193E-04 5,83E-03 ! cell growth GO:0016049 90 46 3,000 1,294E-04 6,199E-03 ! positive regulation of protein modification process GO:0031401 156 90 4,000 1,563E-04 7,344E-03 ! regulation of mast cell proliferation GO:0070666 89 49 3,000 1,658E-04 7,644E-03 ! phosphoinositide phosphorylation GO:0046854 40 20 2,000 1,837E-04 8,31E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 2,000 1,837E-04 8,159E-03 ! apoptotic mitochondrial changes GO:0008637 42 20 2,000 1,837E-04 8,014E-03 ! regulation of glucose import GO:0046324 30 20 2,000 1,837E-04 7,873E-03 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 41 20 2,000 1,837E-04 7,737E-03 ! lipid phosphorylation GO:0046834 43 21 2,000 2,134E-04 8,837E-03 ! cell structure disassembly during apoptosis GO:0006921 32 21 2,000 2,134E-04 8,69E-03 ! positive regulation of inflammatory response GO:0050729 41 21 2,000 2,134E-04 8,547E-03 ! regulation of leukocyte proliferation GO:0070663 97 53 3,000 2,252E-04 8,874E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 3,000 2,252E-04 8,734E-03 ! microtubule-based transport GO:0010970 59 22 2,000 2,461E-04 9,394E-03 ! inactivation of MAPK activity GO:0000188 45 22 2,000 2,461E-04 9,25E-03 ! cellular response to starvation GO:0009267 37 22 2,000 2,461E-04 9,11E-03 ! apoptotic nuclear changes GO:0030262 34 22 2,000 2,461E-04 8,974E-03 ! positive regulation of locomotion GO:0040017 44 22 2,000 2,461E-04 8,842E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of intracellular transport GO:0032388 42 22 2,000 2,461E-04 8,714E-03 ! inner ear receptor cell differentiation GO:0060113 42 22 2,000 2,461E-04 8,589E-03 ! response to UV GO:0009411 120 55 3,000 2,6E-04 8,948E-03 ! regulation of chemotaxis GO:0050920 45 23 2,000 2,819E-04 9,564E-03 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 3,084E-04 0,01032232 ! microvillus organization GO:0032528 8 5 1,000 3,084E-04 0,01018283 GO:0030033|microvillus assembly, ! mRNA transcription GO:0009299 10 5 1,000 3,084E-04 0,01004706 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 3,084E-04 9,915E-03 ! peptidyl-histidine phosphorylation GO:0018106 10 5 1,000 3,084E-04 9,786E-03 ! meiotic chromosome segregation GO:0045132 10 5 1,000 3,084E-04 9,661E-03 ! negative regulation of fibrinolysis GO:0051918 11 5 1,000 3,084E-04 9,538E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 3,084E-04 9,419E-03 ! stem cell division GO:0017145 11 5 1,000 3,084E-04 9,303E-03 GO:0048103|somatic stem cell division, ! DNA catabolic process, endonucleolytic GO:0000737 38 24 2,000 3,208E-04 9,557E-03 ! mechanoreceptor differentiation GO:0042490 48 24 2,000 3,208E-04 9,442E-03 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 2,000 3,63E-04 0,01055847 ! regulation of behavior GO:0050795 48 25 2,000 3,63E-04 0,01043426 ! response to starvation GO:0042594 47 27 2,000 4,579E-04 0,01300771 ! regulation of chromosome organization GO:0033044 49 27 2,000 4,579E-04 0,0128582 ! negative regulation of lymphocyte activation GO:0051250 55 27 2,000 4,579E-04 0,01271208 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 1,000 4,61E-04 0,01265307 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 1,000 4,61E-04 0,01251248 ! early endosome to late endosome transport GO:0045022 16 6 1,000 4,61E-04 0,01237498 ! establishment of spindle localization GO:0051293 16 6 1,000 4,61E-04 0,01224047 GO:0051653|spindle localization, ! enucleate erythrocyte differentiation GO:0043353 14 6 1,000 4,61E-04 0,01210885 ! cytoplasmic microtubule organization GO:0031122 18 6 1,000 4,61E-04 0,01198003 ! negative regulation of B cell activation GO:0050869 14 6 1,000 4,61E-04 0,01185393 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 5,107E-04 0,01299742 ! negative regulation of protein modification process GO:0031400 66 28 2,000 5,107E-04 0,01286343 ! ear development GO:0043583 114 66 3,000 5,238E-04 0,01305739 ! lung development GO:0030324 165 69 3,000 6,201E-04 0,01530294 ! negative regulation of transcription regulator activity GO:0090048 57 30 2,000 6,278E-04 0,01533679 GO:0043433|negative regulation of transcription factor activity, ! regulation of B cell activation GO:0050864 55 30 2,000 6,278E-04 0,01518494 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 6,43E-04 0,01539958 ! N-terminal protein amino acid acetylation GO:0006474 14 7 1,000 6,43E-04 0,01525007 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 6,43E-04 0,01510343 ! anterograde axon cargo transport GO:0008089 18 7 1,000 6,43E-04 0,01495959 ! coenzyme A metabolic process GO:0015936 12 7 1,000 6,43E-04 0,01481846 ! peptidyl-histidine modification GO:0018202 17 7 1,000 6,43E-04 0,01467997 ! cell cycle checkpoint GO:0000075 145 71 3,000 6,909E-04 0,01562949 ! negative regulation of leukocyte activation GO:0002695 60 31 2,000 6,922E-04 0,01551401 ! respiratory tube development GO:0030323 171 72 3,000 7,284E-04 0,01617746 ! respiratory system development GO:0060541 175 74 3,000 8,076E-04 0,01777503 ! leukocyte chemotaxis GO:0030595 55 33 2,000 8,333E-04 0,01817623 GO:0060326|cell chemotaxis, ! regulation of transcription factor activity GO:0051090 137 75 3,000 8,494E-04 0,0183641 GO:0090046|regulation of transcription regulator activity, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 8,541E-04 0,01830369 ! male meiosis GO:0007140 9 8 1,000 8,541E-04 0,01814453 ! regulation of lipid kinase activity GO:0043550 17 8 1,000 8,541E-04 0,01798811 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 8,541E-04 0,01783437 ! ER overload response GO:0006983 13 8 1,000 8,541E-04 0,01768323 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 8,541E-04 0,01753463 ! ATP catabolic process GO:0006200 11 8 1,000 8,541E-04 0,01738851 ! cell fate specification GO:0001708 56 34 2,000 9,102E-04 0,01837671 ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 9,102E-04 0,01822608 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 2,000 1,077E-03 0,02139361 ! negative regulation of DNA binding GO:0043392 67 36 2,000 1,077E-03 0,02122108 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,094E-03 0,02138329 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 1,000 1,094E-03 0,02121358 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 1,094E-03 0,02104654 ! receptor clustering GO:0043113 20 9 1,000 1,094E-03 0,02088212 ! regulation of Notch signaling pathway GO:0008593 24 9 1,000 1,094E-03 0,02072024 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 1,000 1,094E-03 0,02056086 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 1,000 1,094E-03 0,0204039 ! regulation of macrophage differentiation GO:0045649 16 9 1,000 1,094E-03 0,02024933 ! regulation of telomere maintenance GO:0032204 17 9 1,000 1,094E-03 0,02009708 ! negative regulation of cell activation GO:0050866 69 37 2,000 1,167E-03 0,0212825 ! regulation of protein stability GO:0031647 77 38 2,000 1,262E-03 0,02284152 ! negative regulation of transport GO:0051051 164 85 3,000 1,355E-03 0,02433819 ! negative regulation of binding GO:0051100 71 39 2,000 1,362E-03 0,0242838 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 1,363E-03 0,02412197 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 1,000 1,363E-03 0,02394843 ! motor axon guidance GO:0008045 22 10 1,000 1,363E-03 0,02377737 ! alpha-beta T cell differentiation GO:0046632 24 10 1,000 1,363E-03 0,02360873 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 1,000 1,363E-03 0,02344247 ! synaptic vesicle endocytosis GO:0048488 23 10 1,000 1,363E-03 0,02327854 ! midbrain development GO:0030901 14 10 1,000 1,363E-03 0,02311688 ! regulation of fibrinolysis GO:0051917 20 10 1,000 1,363E-03 0,02295746 ! nucleus organization GO:0006997 73 40 2,000 1,466E-03 0,0245335 ! mesenchymal cell development GO:0014031 94 41 2,000 1,575E-03 0,02618259 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of DNA binding GO:0051101 167 89 3,000 1,606E-03 0,02650514 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 1,659E-03 0,02720531 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,659E-03 0,02702394 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 1,659E-03 0,02684497 GO:0010812|negative regulation of cell-substrate adhesion, ! peptide or protein amino-terminal blocking GO:0018409 22 11 1,000 1,659E-03 0,02666836 ! alpha-beta T cell activation GO:0046631 26 11 1,000 1,659E-03 0,02649406 ! purine ribonucleotide catabolic process GO:0009154 17 11 1,000 1,659E-03 0,02632202 ! regulation of intracellular protein transport GO:0033157 86 42 2,000 1,69E-03 0,02663182 ! T cell differentiation GO:0030217 93 42 2,000 1,69E-03 0,0264611 ! regulation of T cell differentiation GO:0045580 78 42 2,000 1,69E-03 0,02629256 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 2,000 1,809E-03 0,02797062 ! regulation of T cell proliferation GO:0042129 80 43 2,000 1,809E-03 0,02779471 ! positive regulation of response to external stimulus GO:0032103 88 44 2,000 1,933E-03 0,02952071 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 1,984E-03 0,0301019 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 1,984E-03 0,02991609 ! oligodendrocyte differentiation GO:0048709 17 12 1,000 1,984E-03 0,02973256 ! regulation of interleukin-12 production GO:0032655 19 12 1,000 1,984E-03 0,02955126 ! histone acetylation GO:0016573 27 12 1,000 1,984E-03 0,02937216 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,984E-03 0,02919522 ! localization within membrane GO:0051668 26 12 1,000 1,984E-03 0,0290204 ! ATP synthesis coupled electron transport GO:0042773 69 45 2,000 2,063E-03 0,02999991 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of nucleocytoplasmic transport GO:0046822 92 46 2,000 2,198E-03 0,03177252 ! leukocyte migration GO:0050900 75 46 2,000 2,198E-03 0,03158562 ! positive regulation of protein transport GO:0051222 80 46 2,000 2,198E-03 0,03140091 ! cartilage condensation GO:0001502 22 13 1,000 2,336E-03 0,03317733 ! ribonucleotide catabolic process GO:0009261 21 13 1,000 2,336E-03 0,03298556 ! nucleoside triphosphate catabolic process GO:0009143 22 13 1,000 2,336E-03 0,03279598 ! regulation of monooxygenase activity GO:0032768 35 13 1,000 2,336E-03 0,03260858 ! histone methylation GO:0016571 29 13 1,000 2,336E-03 0,0324233 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 2,336E-03 0,03224012 ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 2,336E-03 0,032059 ! positive regulation of cell cycle GO:0045787 96 48 2,000 2,484E-03 0,03390003 ! positive regulation of defense response GO:0031349 88 48 2,000 2,484E-03 0,0337117 ! cellular component disassembly GO:0022411 89 48 2,000 2,484E-03 0,03352545 ! regulation of inflammatory response GO:0050727 84 48 2,000 2,484E-03 0,03334124 ! JAK-STAT cascade GO:0007259 82 48 2,000 2,484E-03 0,03315905 ! regulation of lymphocyte differentiation GO:0045619 92 49 2,000 2,635E-03 0,03498604 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 2,715E-03 0,03585462 ! induction of apoptosis by extracellular signals GO:0008624 99 50 2,000 2,792E-03 0,03666852 ! activation of caspase activity GO:0006919 95 50 2,000 2,792E-03 0,03647243 ! negative regulation of immune system process GO:0002683 101 51 2,000 2,954E-03 0,03838836 ! N-terminal protein amino acid modification GO:0031365 30 15 1,000 3,121E-03 0,0403463 ! actin cytoskeleton reorganization GO:0031532 38 15 1,000 3,121E-03 0,04013395 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 3,121E-03 0,03992383 ! G1/S transition checkpoint GO:0031575 37 15 1,000 3,121E-03 0,03971589 ! intermediate filament cytoskeleton organization GO:0045104 34 15 1,000 3,121E-03 0,03951011 ! Notch signaling pathway GO:0007219 111 52 2,000 3,122E-03 0,03931747 ! histone modification GO:0016570 104 52 2,000 3,122E-03 0,03911584 ! respiratory electron transport chain GO:0022904 83 53 2,000 3,296E-03 0,04108281 ! inner ear development GO:0048839 89 53 2,000 3,296E-03 0,04087427 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 2,000 3,296E-03 0,04066784 ! regulation of muscle contraction GO:0006937 94 54 2,000 3,476E-03 0,04266879 ! covalent chromatin modification GO:0016569 115 54 2,000 3,476E-03 0,04245545 ! embryonic hindlimb morphogenesis GO:0035116 36 16 1,000 3,554E-03 0,04319794 ! stem cell development GO:0048864 46 16 1,000 3,554E-03 0,04298409 GO:0019827|stem cell maintenance, ! intermediate filament-based process GO:0045103 36 16 1,000 3,554E-03 0,04277234 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 3,554E-03 0,04256267 ! neuromuscular synaptic transmission GO:0007274 34 16 1,000 3,554E-03 0,04235505 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 4,013E-03 0,04759395 ! signal complex assembly GO:0007172 47 17 1,000 4,013E-03 0,04736403 ! regulation of survival gene product expression GO:0045884 38 17 1,000 4,013E-03 0,04713632 ! positive regulation of caspase activity GO:0043280 108 57 2,000 4,05E-03 0,04734165 GO:0010952|positive regulation of peptidase activity, ! regulation of intracellular transport GO:0032386 108 57 2,000 4,05E-03 0,04711621 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 4,498E-03 0,05208253 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 4,498E-03 0,05183686 ! lipid modification GO:0030258 112 60 2,000 4,679E-03 0,05366532 ! DNA catabolic process GO:0006308 94 60 2,000 4,679E-03 0,05341455 ! regulation of heart contraction GO:0008016 123 61 2,000 4,901E-03 0,05568827 ! negative regulation of response to stimulus GO:0048585 106 61 2,000 4,901E-03 0,05543045 ! regulation of neuronal synaptic plasticity GO:0048168 51 19 1,000 5,009E-03 0,05639274 ! neuromuscular junction development GO:0007528 43 19 1,000 5,009E-03 0,05613406 ! skeletal system morphogenesis GO:0048705 118 63 2,000 5,364E-03 0,05983323 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 1,000 5,545E-03 0,06157752 ! protein amino acid acetylation GO:0006473 41 20 1,000 5,545E-03 0,06129889 ! response to alkaloid GO:0043279 38 20 1,000 5,545E-03 0,06102276 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 5,545E-03 0,06074912 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 5,545E-03 0,06047792 ! purine nucleotide catabolic process GO:0006195 32 20 1,000 5,545E-03 0,06020913 ! integrin-mediated signaling pathway GO:0007229 160 64 2,000 5,605E-03 0,06058383 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 5,605E-03 0,06031694 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 1,000 6,106E-03 0,06543059 ! hindlimb morphogenesis GO:0035137 47 22 1,000 6,693E-03 0,07139681 ! stem cell differentiation GO:0048863 57 22 1,000 6,693E-03 0,07108639 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 6,693E-03 0,07077866 ! G1 phase GO:0051318 44 22 1,000 6,693E-03 0,07047358 ! peptidyl-serine modification GO:0018209 50 22 1,000 6,693E-03 0,07017111 ! positive regulation of B cell activation GO:0050871 42 22 1,000 6,693E-03 0,06987124 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 6,693E-03 0,06957391 ! protein stabilization GO:0050821 41 22 1,000 6,693E-03 0,06927911 ! positive regulation of DNA replication GO:0045740 44 23 1,000 7,303E-03 0,07528026 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 7,303E-03 0,07496395 GO:0010810|regulation of cell-substrate adhesion, ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 7,303E-03 0,0746503 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 7,303E-03 0,07433925 ! nerve-nerve synaptic transmission GO:0007270 59 23 1,000 7,303E-03 0,07403079 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 7,938E-03 0,08013274 ! purine ribonucleoside metabolic process GO:0046128 38 24 1,000 7,938E-03 0,07980297 GO:0042278|purine nucleoside metabolic process, ! sex determination GO:0007530 48 24 1,000 7,938E-03 0,07947591 ! synaptic vesicle transport GO:0048489 52 24 1,000 7,938E-03 0,07915152 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 7,938E-03 0,07882977 ! negative regulation of catabolic process GO:0009895 52 24 1,000 7,938E-03 0,07851062 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 7,938E-03 0,07819404 ! regulation of caspase activity GO:0043281 136 74 2,000 8,372E-03 0,08213953 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 8,597E-03 0,08400509 ! receptor metabolic process GO:0043112 53 25 1,000 8,597E-03 0,0836704 ! phosphoinositide-mediated signaling GO:0048015 141 75 2,000 8,685E-03 0,0842003 ! learning or memory GO:0007611 161 76 2,000 9,006E-03 0,08695985 ! lymphocyte differentiation GO:0030098 193 76 2,000 9,006E-03 0,08661749 ! myelination GO:0042552 50 26 1,000 9,279E-03 0,08889479 ! protein amino acid alkylation GO:0008213 59 26 1,000 9,279E-03 0,08854754 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 9,279E-03 0,088203 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 9,279E-03 0,08786113 ! positive regulation of nuclear division GO:0051785 41 26 1,000 9,279E-03 0,0875219 GO:0045840|positive regulation of mitosis, ! phosphoinositide metabolic process GO:0030384 146 77 2,000 9,333E-03 0,08769197 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 9,333E-03 0,08735598 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 1,000 9,984E-03 0,09309974 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 9,984E-03 0,09274575 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 0,01000755 0,09260774 ! meiosis GO:0007126 143 81 2,000 0,01071003 0,09873433 GO:0051327|M phase of meiotic cell cycle, ! response to hypoxia GO:0001666 178 81 2,000 0,01071003 0,09836315 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 0,01071325 0,09802423 ! protein amino acid acylation GO:0043543 59 28 1,000 0,01071325 0,09765847 ! group transfer coenzyme metabolic process GO:0006752 53 28 1,000 0,01071325 0,09729542 ! regulation of peptidase activity GO:0052547 150 82 2,000 0,01107171 0,10017848 ! meiotic cell cycle GO:0051321 144 82 2,000 0,01107171 0,09980881 ! response to oxygen levels GO:0070482 183 83 2,000 0,01144039 0,10275317 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 0,0114648 0,10259525 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 0,0114648 0,10222081 ! somitogenesis GO:0001756 52 29 1,000 0,0114648 0,1018491 ! T cell activation GO:0042110 189 84 2,000 0,01181608 0,1045894 ! response to nutrient GO:0007584 135 84 2,000 0,01181608 0,10421182 ! regulation of ligase activity GO:0051340 147 84 2,000 0,01181608 0,10383696 ! cholesterol metabolic process GO:0008203 148 85 2,000 0,0121988 0,10681604 ! mitochondrion organization GO:0007005 159 87 2,000 0,01298544 0,11329798 ! regulation of protein transport GO:0051223 165 87 2,000 0,01298544 0,11289478 GO:0070201|regulation of establishment of protein localization, ! male gonad development GO:0008584 56 31 1,000 0,01303519 0,11292545 ! iron ion homeostasis GO:0055072 60 31 1,000 0,01303519 0,11252642 ! erythrocyte differentiation GO:0030218 62 31 1,000 0,01303519 0,1121302 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 0,01303519 0,11173677 ! ensheathment of neurons GO:0007272 64 31 1,000 0,01303519 0,11134608 GO:0008366|axon ensheathment, ! response to heat GO:0009408 54 31 1,000 0,01303519 0,11095811 ! cellular respiration GO:0045333 143 88 2,000 0,01338939 0,11357737 ! spindle organization GO:0007051 50 32 1,000 0,0138535 0,11710758 ! metanephros development GO:0001656 81 32 1,000 0,0138535 0,11670376 ! response to mechanical stimulus GO:0009612 60 32 1,000 0,0138535 0,11630271 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 0,0138535 0,11590442 ! peripheral nervous system development GO:0007422 68 32 1,000 0,0138535 0,11550884 ! BMP signaling pathway GO:0030509 71 32 1,000 0,0138535 0,11511595 ! hindbrain development GO:0030902 65 32 1,000 0,0138535 0,11472573 ! regulation of cell cycle process GO:0010564 161 90 2,000 0,01421863 0,11735175 ! oxidative phosphorylation GO:0006119 152 90 2,000 0,01421863 0,11695663 ! ossification GO:0001503 205 91 2,000 0,01464396 0,12005095 ! positive regulation of gene-specific transcription GO:0043193 70 33 1,000 0,01469351 0,12005432 ! negative regulation of protein transport GO:0051224 74 33 1,000 0,01469351 0,11965414 ! bone development GO:0060348 206 92 2,000 0,01507643 0,12236453 ! regulation of cell adhesion GO:0030155 241 92 2,000 0,01507643 0,12195935 ! positive regulation of MAP kinase activity GO:0043406 174 93 2,000 0,01551608 0,12510156 ! glial cell differentiation GO:0010001 67 34 1,000 0,01555497 0,12500258 ! regulation of ARF GTPase activity GO:0032312 73 34 1,000 0,01555497 0,12459273 ! sterol metabolic process GO:0016125 166 94 2,000 0,0159629 0,12744235 ! regulation of defense response GO:0031347 171 95 2,000 0,01641691 0,13064009 ! regulation of synaptic plasticity GO:0048167 78 35 1,000 0,0164376 0,13038009 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,0164376 0,12995815 ! sex differentiation GO:0007548 171 96 2,000 0,01687812 0,13301047 ! regulation of T cell activation GO:0050863 175 96 2,000 0,01687812 0,13258278 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,01734116 0,13578353 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 0,01734654 0,13539167 ! regulation of protein localization GO:0032880 188 97 2,000 0,01734654 0,13496049 ! leukocyte differentiation GO:0002521 232 98 2,000 0,01782217 0,13822086 ! forebrain development GO:0030900 210 98 2,000 0,01782217 0,13778346 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 1,000 0,01826538 0,14076443 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,01826538 0,14032177 ! sister chromatid segregation GO:0000819 65 37 1,000 0,01826538 0,13988189 ! odontogenesis GO:0042476 74 37 1,000 0,01826538 0,13944476 ! maintenance of protein location in cell GO:0032507 89 37 1,000 0,01826538 0,13901035 ! regulation of microtubule-based process GO:0032886 86 37 1,000 0,01826538 0,13857864 ! skeletal muscle tissue development GO:0007519 223 100 2,000 0,01879513 0,14215632 GO:0060538|skeletal muscle organ development, ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 0,01921 0,14484577 ! meiosis I GO:0007127 74 38 1,000 0,01921 0,14440009 ! glycogen metabolic process GO:0005977 63 38 1,000 0,01921 0,14395715 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 0,01921 0,14351691 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 0,02017477 0,15026511 ! carbohydrate homeostasis GO:0033500 59 39 1,000 0,02017477 0,14980838 GO:0042593|glucose homeostasis, ! nucleotide catabolic process GO:0009166 70 39 1,000 0,02017477 0,14935442 ! erythrocyte homeostasis GO:0034101 75 39 1,000 0,02017477 0,14890319 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,02017477 0,14845469 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! glucan metabolic process GO:0044042 64 39 1,000 0,02017477 0,14800888 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 1,000 0,02115943 0,15476792 ! learning GO:0007612 82 40 1,000 0,02115943 0,15430593 ! lipid homeostasis GO:0055088 75 40 1,000 0,02115943 0,15384669 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,02115943 0,15339017 ! gliogenesis GO:0042063 91 41 1,000 0,02216374 0,16019529 ! maintenance of protein location GO:0045185 95 41 1,000 0,02216374 0,15972274 ! ear morphogenesis GO:0042471 64 42 1,000 0,02318744 0,16660856 ! ribonucleoside metabolic process GO:0009119 64 42 1,000 0,02318744 0,16611997 ! cytokinesis GO:0000910 84 42 1,000 0,02318744 0,16563424 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,02423029 0,172579 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 1,000 0,02423029 0,17207732 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 1,000 0,02423029 0,17157854 ! striated muscle cell differentiation GO:0051146 91 43 1,000 0,02423029 0,17108265 ! development of primary male sexual characteristics GO:0046546 80 43 1,000 0,02423029 0,17058962 ! segmentation GO:0035282 78 43 1,000 0,02423029 0,17009942 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 0,02423029 0,16961202 ! energy reserve metabolic process GO:0006112 76 44 1,000 0,02529205 0,17653848 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 1,000 0,02529205 0,17603552 ! biopolymer methylation GO:0043414 91 45 1,000 0,02637246 0,1830339 ! maintenance of location in cell GO:0051651 101 45 1,000 0,02637246 0,18251539 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,02747131 0,18958306 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 1,000 0,02747131 0,18904902 ! pigmentation GO:0043473 103 46 1,000 0,02747131 0,18851799 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02768331 0,18944069 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02768331 0,18891152 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02768331 0,18838531 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02768331 0,18786201 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02768331 0,18734162 ! neuron fate determination GO:0048664 7 5 0,000 0,02768331 0,1868241 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02768331 0,18630943 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02768331 0,1857976 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02768331 0,18528856 ! polyol transport GO:0015791 12 5 0,000 0,02768331 0,18478231 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02768331 0,18427881 ! response to superoxide GO:0000303 10 5 0,000 0,02768331 0,18377806 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02768331 0,18328001 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02768331 0,18278466 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02768331 0,18229198 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02768331 0,18180195 ! female meiosis GO:0007143 10 5 0,000 0,02768331 0,18131454 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02768331 0,18082975 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02768331 0,18034753 ! hypothalamus development GO:0021854 9 5 0,000 0,02768331 0,17986789 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02768331 0,17939078 ! cobalt ion transport GO:0006824 11 5 0,000 0,02768331 0,1789162 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02768331 0,17844413 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02768331 0,17797454 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02768331 0,17750741 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02768331 0,17704274 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02768331 0,17658048 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02768331 0,17612064 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02768331 0,17566318 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02768331 0,1752081 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02768331 0,17475536 ! transposition GO:0032196 9 5 0,000 0,02768331 0,17430496 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02768331 0,17385688 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,02768331 0,17341109 ! negative chemotaxis GO:0050919 16 5 0,000 0,02768331 0,17296758 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02768331 0,17252634 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02768331 0,17208734 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02768331 0,17165057 ! behavioral response to pain GO:0048266 10 5 0,000 0,02768331 0,17121601 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02768331 0,17078365 ! Notch receptor processing GO:0007220 11 5 0,000 0,02768331 0,17035346 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02768331 0,16992544 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,02768331 0,16949956 ! micturition GO:0060073 9 5 0,000 0,02768331 0,16907581 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02768331 0,16865418 ! copulation GO:0007620 9 5 0,000 0,02768331 0,16823464 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02768331 0,16781718 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02768331 0,16740179 ! bioluminescence GO:0008218 9 5 0,000 0,02768331 0,16698846 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02768331 0,16657715 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02768331 0,16616787 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02768331 0,1657606 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02768331 0,16535532 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02768331 0,16495201 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02768331 0,16455067 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02768331 0,16415127 ! grooming behavior GO:0007625 6 5 0,000 0,02768331 0,16375381 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02768331 0,16335827 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02768331 0,16296464 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02768331 0,1625729 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02768331 0,16218303 ! response to protozoan GO:0001562 13 5 0,000 0,02768331 0,16179504 ! positive regulation of glycolysis GO:0045821 13 5 0,000 0,02768331 0,16140889 ! lymph vessel development GO:0001945 10 5 0,000 0,02768331 0,16102458 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02768331 0,1606421 ! endochondral ossification GO:0001958 17 5 0,000 0,02768331 0,16026143 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02768331 0,15988256 ! single strand break repair GO:0000012 8 5 0,000 0,02768331 0,15950548 ! parathyroid gland development GO:0060017 14 5 0,000 0,02768331 0,15913018 ! anagen GO:0042640 7 5 0,000 0,02768331 0,15875663 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02768331 0,15838484 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02768331 0,15801478 ! cytokine secretion GO:0050663 15 5 0,000 0,02768331 0,15764644 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02768331 0,15727983 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02768331 0,15691491 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02768331 0,15655168 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02768331 0,15619013 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02768331 0,15583024 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02768331 0,15547201 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02768331 0,15511542 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02768331 0,15476047 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02768331 0,15440713 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02768331 0,15405541 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02768331 0,15370528 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02768331 0,15335675 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02768331 0,15300978 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02768331 0,15266439 ! valine metabolic process GO:0006573 12 5 0,000 0,02768331 0,15232055 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02768331 0,15197826 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02768331 0,1516375 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02768331 0,15129827 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02768331 0,15096055 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02768331 0,15062433 ! polyol catabolic process GO:0046174 9 5 0,000 0,02768331 0,15028961 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02768331 0,14995637 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02768331 0,14962461 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02768331 0,14929432 ! muscle cell migration GO:0014812 8 5 0,000 0,02768331 0,14896547 ! mitochondrial fission GO:0000266 8 5 0,000 0,02768331 0,14863808 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02768331 0,14831212 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02768331 0,14798758 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02768331 0,14766446 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02768331 0,14734276 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02768331 0,14702245 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02768331 0,14670352 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02768331 0,14638598 ! monocyte activation GO:0042117 10 5 0,000 0,02768331 0,14606982 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02768331 0,14575501 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02768331 0,14544156 ! response to food GO:0032094 6 5 0,000 0,02768331 0,14512945 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02768331 0,14481868 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02768331 0,14450924 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02768331 0,14420112 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02768331 0,14389431 ! forebrain neuron development GO:0021884 13 5 0,000 0,02768331 0,1435888 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02768331 0,14328459 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02768331 0,14298166 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02768331 0,14268001 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02768331 0,14237963 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02768331 0,14208051 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02768331 0,14178265 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02768331 0,14148604 ! lipid glycosylation GO:0030259 7 5 0,000 0,02768331 0,14119066 ! nucleobase transport GO:0015851 6 5 0,000 0,02768331 0,14089651 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02768331 0,14060359 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02768331 0,14031188 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02768331 0,14002138 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02768331 0,13973208 ! basic amino acid transport GO:0015802 12 5 0,000 0,02768331 0,13944397 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02768331 0,13915705 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02768331 0,1388713 ! actin nucleation GO:0045010 11 5 0,000 0,02768331 0,13858673 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02768331 0,13830332 ! depurination GO:0045007 5 5 0,000 0,02768331 0,13802107 ! depyrimidination GO:0045008 10 5 0,000 0,02768331 0,13773997 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02768331 0,13746001 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02768331 0,13718119 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02768331 0,13690349 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02768331 0,13662692 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02768331 0,13635146 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02768331 0,13607711 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02768331 0,13580387 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02768331 0,13553171 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02768331 0,13526065 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02768331 0,13499067 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02768331 0,13472176 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02768331 0,13445393 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02768331 0,13418715 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02768331 0,13392144 ! response to arsenic GO:0046685 11 5 0,000 0,02768331 0,13365677 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02768331 0,13339315 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02768331 0,13313056 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02768331 0,13286901 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02768331 0,13260848 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02768331 0,13234897 ! response to mercury ion GO:0046689 8 5 0,000 0,02768331 0,13209048 ! response to cadmium ion GO:0046686 7 5 0,000 0,02768331 0,13183299 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02768331 0,13157651 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02768331 0,13132102 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02768331 0,13106652 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02768331 0,13081301 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02768331 0,13056047 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02768331 0,13030891 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02768331 0,13005832 ! decidualization GO:0046697 11 5 0,000 0,02768331 0,12980868 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02768331 0,12956001 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02768331 0,12931228 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02768331 0,12906551 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02768331 0,12881967 ! embryonic cleavage GO:0040016 6 5 0,000 0,02768331 0,12857476 ! peroxisome fission GO:0016559 5 5 0,000 0,02768331 0,12833079 ! histone demethylation GO:0016577 13 5 0,000 0,02768331 0,12808774 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02768331 0,1278456 ! mitotic recombination GO:0006312 9 5 0,000 0,02768331 0,12760439 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02768331 0,12736408 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02768331 0,12712467 ! metaphase plate congression GO:0051310 7 5 0,000 0,02768331 0,12688616 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02768331 0,12664855 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02768331 0,12641182 ! enteric nervous system development GO:0048484 8 5 0,000 0,02768331 0,12617598 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02768331 0,12594101 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02768331 0,12570692 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02768331 0,1254737 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02768331 0,12524134 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02768331 0,12500984 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02768331 0,1247792 ! B cell homeostasis GO:0001782 13 5 0,000 0,02768331 0,1245494 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02768331 0,12432045 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02768331 0,12409234 ! metaphase GO:0051323 11 5 0,000 0,02768331 0,12386506 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02768331 0,12363862 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02768331 0,123413 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02768331 0,12318821 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02768331 0,12296423 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02768331 0,12274106 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02768331 0,1225187 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02768331 0,12229715 ! response to redox state GO:0051775 6 5 0,000 0,02768331 0,1220764 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02768331 0,12185644 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02768331 0,12163727 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02768331 0,1214189 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02768331 0,1212013 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02768331 0,12098448 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02768331 0,12076844 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02768331 0,12055316 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02768331 0,12033866 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02768331 0,12012491 ! striatum development GO:0021756 14 5 0,000 0,02768331 0,11991192 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02768331 0,11969969 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02768331 0,11948821 ! glial cell migration GO:0008347 10 5 0,000 0,02768331 0,11927747 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02768331 0,11906747 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02768331 0,11885822 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02768331 0,11864969 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02768331 0,1184419 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02768331 0,11823483 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02768331 0,11802849 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02768331 0,11782287 ! neuroprotection GO:0043526 8 5 0,000 0,02768331 0,11761796 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02768331 0,11741376 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02768331 0,11721027 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02768331 0,11700748 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02768331 0,1168054 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02768331 0,11660401 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02768331 0,11640331 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02768331 0,11620331 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02768331 0,11600399 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02768331 0,11580535 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02768331 0,11560739 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02768331 0,11541011 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02768331 0,1152135 ! spindle assembly GO:0051225 6 5 0,000 0,02768331 0,11501756 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02768331 0,11482228 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02768331 0,11462767 ! protein palmitoylation GO:0018345 12 5 0,000 0,02768331 0,11443371 ! drug metabolic process GO:0017144 7 5 0,000 0,02768331 0,11424041 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02768331 0,11404777 ! organ regeneration GO:0031100 7 5 0,000 0,02768331 0,11385577 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02768331 0,11366441 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02768331 0,1134737 ! response to insulin stimulus GO:0032868 98 47 1,000 0,02858833 0,1169871 ! endosome transport GO:0016197 127 48 1,000 0,02972331 0,12142817 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,02972331 0,12122546 ! male sex differentiation GO:0046661 93 48 1,000 0,02972331 0,12102341 ! methylation GO:0032259 97 48 1,000 0,02972331 0,12082204 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,030876 0,12529913 ! regulation of action potential GO:0001508 102 50 1,000 0,03204618 0,12983219 ! regulation of ARF protein signal transduction GO:0032012 115 50 1,000 0,03204618 0,12961724 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03312778 0,13377052 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03312778 0,13354978 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,03312778 0,13332976 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,03312778 0,13311047 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03312778 0,1328919 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,03312778 0,13267404 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,03312778 0,1324569 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03312778 0,13224047 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,03312778 0,13202474 ! response to oxygen radical GO:0000305 11 6 0,000 0,03312778 0,13180972 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,03312778 0,13159539 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,03312778 0,13138176 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,03312778 0,13116883 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,03312778 0,13095658 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03312778 0,13074502 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03312778 0,13053414 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,03312778 0,13032394 ! forebrain regionalization GO:0021871 9 6 0,000 0,03312778 0,13011441 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03312778 0,12990556 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03312778 0,12969738 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,03312778 0,12948986 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03312778 0,12928301 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,03312778 0,12907682 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03312778 0,12887128 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,03312778 0,1286664 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,03312778 0,12846217 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03312778 0,12825858 ! malate metabolic process GO:0006108 13 6 0,000 0,03312778 0,12805564 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,03312778 0,12785334 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,03312778 0,12765168 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,03312778 0,12745065 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,03312778 0,12725026 ! protein refolding GO:0042026 15 6 0,000 0,03312778 0,12705049 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03312778 0,12685136 ! opsonization GO:0008228 8 6 0,000 0,03312778 0,12665284 ! mating behavior GO:0007617 7 6 0,000 0,03312778 0,12645495 ! erythrocyte maturation GO:0043249 8 6 0,000 0,03312778 0,12625767 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,03312778 0,126061 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,03312778 0,12586495 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,03312778 0,12566951 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,03312778 0,12547467 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03312778 0,12528044 ! response to interferon-gamma GO:0034341 16 6 0,000 0,03312778 0,12508681 ! toxin metabolic process GO:0009404 11 6 0,000 0,03312778 0,12489377 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,03312778 0,12470133 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,03312778 0,12450948 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,03312778 0,12431823 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,03312778 0,12412755 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,03312778 0,12393747 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,03312778 0,12374796 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,03312778 0,12355903 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,03312778 0,12337068 ! thymic T cell selection GO:0045061 16 6 0,000 0,03312778 0,1231829 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,03312778 0,12299569 ! protein lipoylation GO:0009249 10 6 0,000 0,03312778 0,12280905 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,03312778 0,12262298 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,03312778 0,12243747 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03312778 0,12225252 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,03312778 0,12206812 ! glutamate catabolic process GO:0006538 12 6 0,000 0,03312778 0,12188428 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,03312778 0,121701 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03312778 0,12151827 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,03312778 0,12133608 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03312778 0,12115444 ! hyperosmotic response GO:0006972 10 6 0,000 0,03312778 0,12097334 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,03312778 0,12079278 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,03312778 0,12061276 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,03312778 0,12043328 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03312778 0,12025433 ! urea metabolic process GO:0019627 7 6 0,000 0,03312778 0,12007591 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03312778 0,11989802 ! neutrophil activation GO:0042119 7 6 0,000 0,03312778 0,11972066 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03312778 0,11954382 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,03312778 0,1193675 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03312778 0,1191917 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,03312778 0,11901642 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,03312778 0,11884165 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03312778 0,1186674 ! neuron apoptosis GO:0051402 15 6 0,000 0,03312778 0,11849365 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03312778 0,11832042 ! T cell mediated immunity GO:0002456 17 6 0,000 0,03312778 0,11814769 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03312778 0,11797546 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,03312778 0,11780373 ! carnitine transport GO:0015879 10 6 0,000 0,03312778 0,11763251 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03312778 0,11746178 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,03312778 0,11729154 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,03312778 0,1171218 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,03312778 0,11695255 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03312778 0,11678379 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,03312778 0,11661551 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,03312778 0,11644772 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,03312778 0,11628041 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,03312778 0,11611358 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,03312778 0,11594723 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,03312778 0,11578135 ! response to UV-C GO:0010225 14 6 0,000 0,03312778 0,11561595 ! astrocyte development GO:0014002 16 6 0,000 0,03312778 0,11545102 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,03312778 0,11528656 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03312778 0,11512257 ! interaction with symbiont GO:0051702 14 6 0,000 0,03312778 0,11495904 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03312778 0,11479598 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,03312778 0,11463338 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,03312778 0,11447124 ! response to copper ion GO:0046688 10 6 0,000 0,03312778 0,11430956 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,03312778 0,11414833 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03312778 0,11398756 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,03312778 0,11382724 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03312778 0,11366737 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,03312778 0,11350795 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03312778 0,11334897 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,03312778 0,11319044 ! hair follicle maturation GO:0048820 8 6 0,000 0,03312778 0,11303235 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03312778 0,11287471 ! Schwann cell development GO:0014044 15 6 0,000 0,03312778 0,1127175 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,03312778 0,11256073 ! response to pheromone GO:0019236 6 6 0,000 0,03312778 0,1124044 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,03312778 0,1122485 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,03312778 0,11209303 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,03312778 0,11193799 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,03312778 0,11178338 ! subpallium development GO:0021544 15 6 0,000 0,03312778 0,11162919 ! neural tube patterning GO:0021532 8 6 0,000 0,03312778 0,11147543 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,03312778 0,1113221 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,03312778 0,11116918 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03312778 0,11101669 ! G2 phase GO:0051319 16 6 0,000 0,03312778 0,11086461 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,03312778 0,11071295 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,03312778 0,1105617 ! oxygen homeostasis GO:0032364 10 6 0,000 0,03312778 0,11041087 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03312778 0,11026044 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,03312778 0,11011043 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03312778 0,10996082 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,03312778 0,10981162 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03312778 0,10966283 ! receptor internalization GO:0031623 11 6 0,000 0,03312778 0,10951443 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,03312778 0,10936644 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,03312778 0,10921885 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,03312778 0,10907165 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03312778 0,10892485 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,03312778 0,10877845 ! protein deubiquitination GO:0016579 16 6 0,000 0,03312778 0,10863244 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,03312778 0,10848682 ! protein destabilization GO:0031648 9 6 0,000 0,03312778 0,10834159 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,03312778 0,10819674 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03312778 0,10805229 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,03312778 0,10790822 ! regulation of viral transcription GO:0046782 11 6 0,000 0,03312778 0,10776453 ! progesterone metabolic process GO:0042448 12 6 0,000 0,03312778 0,10762123 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,03312778 0,10747831 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,03312778 0,10733576 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,03312778 0,1071936 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,03312778 0,10705181 ! determination of adult lifespan GO:0008340 17 6 0,000 0,03312778 0,10691039 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,03312778 0,10676935 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03312778 0,10662868 ! neural plate development GO:0001840 9 6 0,000 0,03312778 0,10648838 ! catecholamine transport GO:0051937 9 6 0,000 0,03312778 0,10634844 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,03312778 0,10620888 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03312778 0,10606968 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,03312778 0,10593084 ! maternal placenta development GO:0001893 12 6 0,000 0,03312778 0,10579237 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,03312778 0,10565426 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03312778 0,10551651 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,03312778 0,10537912 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,03312778 0,10524209 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,03312778 0,10510541 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,03312778 0,10496909 GO:0055081|anion homeostasis, ! viral infectious cycle GO:0019058 104 51 1,000 0,03323361 0,10516801 ! response to temperature stimulus GO:0009266 84 51 1,000 0,03323361 0,10503196 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,03323361 0,10489626 ! positive regulation of binding GO:0051099 88 52 1,000 0,03443806 0,10855766 ! chromatin remodeling GO:0006338 122 53 1,000 0,03565932 0,11226252 ! vesicle organization GO:0016050 127 53 1,000 0,03565932 0,11211804 ! synapse organization GO:0050808 102 53 1,000 0,03565932 0,11197393 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,03689715 0,11571212 ! regulation of translational initiation GO:0006446 87 54 1,000 0,03689715 0,11556377 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,03689715 0,1154158 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,03815134 0,11918634 ! tRNA transcription GO:0009304 17 7 0,000 0,03854192 0,12025275 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03854192 0,12009936 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03854192 0,11994637 ! regulation of helicase activity GO:0051095 16 7 0,000 0,03854192 0,11979377 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03854192 0,11964155 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03854192 0,11948972 ! sleep GO:0030431 16 7 0,000 0,03854192 0,11933828 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03854192 0,11918722 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03854192 0,11903654 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03854192 0,11888624 ! prostate gland development GO:0030850 14 7 0,000 0,03854192 0,11873632 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03854192 0,11858678 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03854192 0,11843761 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03854192 0,11828882 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03854192 0,1181404 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03854192 0,11799236 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03854192 0,11784468 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03854192 0,11769737 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03854192 0,11755044 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03854192 0,11740387 ! glycolipid transport GO:0046836 11 7 0,000 0,03854192 0,11725766 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03854192 0,11711182 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,03854192 0,11696634 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03854192 0,11682122 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03854192 0,11667646 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03854192 0,11653205 ! mRNA stabilization GO:0048255 18 7 0,000 0,03854192 0,11638801 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 16 7 0,000 0,03854192 0,11624432 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03854192 0,11610099 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03854192 0,115958 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03854192 0,11581538 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03854192 0,1156731 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03854192 0,11553117 ! lipoprotein transport GO:0042953 14 7 0,000 0,03854192 0,11538958 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03854192 0,11524835 ! rhythmic behavior GO:0007622 17 7 0,000 0,03854192 0,11510746 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03854192 0,11496691 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03854192 0,11482671 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03854192 0,11468685 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03854192 0,11454732 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03854192 0,11440814 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03854192 0,1142693 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03854192 0,11413079 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03854192 0,11399261 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03854192 0,11385478 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03854192 0,11371727 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03854192 0,1135801 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03854192 0,11344325 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03854192 0,11330674 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03854192 0,11317055 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03854192 0,11303469 ! spinal cord patterning GO:0021511 14 7 0,000 0,03854192 0,11289916 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03854192 0,11276395 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03854192 0,11262907 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03854192 0,1124945 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03854192 0,11236026 ! adrenal gland development GO:0030325 17 7 0,000 0,03854192 0,11222634 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03854192 0,11209274 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03854192 0,11195945 ! ovulation GO:0030728 10 7 0,000 0,03854192 0,11182648 ! adenohypophysis development GO:0021984 11 7 0,000 0,03854192 0,11169383 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03854192 0,11156149 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03854192 0,11142947 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03854192 0,11129775 ! microtubule nucleation GO:0007020 21 7 0,000 0,03854192 0,11116635 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03854192 0,11103526 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03854192 0,11090448 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03854192 0,110774 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03854192 0,11064383 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03854192 0,11051397 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03854192 0,11038441 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03854192 0,11025515 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03854192 0,1101262 ! galactose metabolic process GO:0006012 13 7 0,000 0,03854192 0,10999755 ! vesicle fusion GO:0006906 20 7 0,000 0,03854192 0,10986919 ! response to dietary excess GO:0002021 8 7 0,000 0,03854192 0,10974114 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03854192 0,10961339 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03854192 0,10948593 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03854192 0,10935877 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03854192 0,1092319 ! organ growth GO:0035265 15 7 0,000 0,03854192 0,10910533 ! nucleoside transport GO:0015858 11 7 0,000 0,03854192 0,10897905 ! nucleoside salvage GO:0043174 11 7 0,000 0,03854192 0,10885306 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03854192 0,10872737 ! male sex determination GO:0030238 15 7 0,000 0,03854192 0,10860196 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03854192 0,10847684 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03854192 0,10835201 ! parturition GO:0007567 16 7 0,000 0,03854192 0,10822747 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03854192 0,10810321 ! rRNA modification GO:0000154 14 7 0,000 0,03854192 0,10797924 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03854192 0,10785556 ! spindle checkpoint GO:0031577 16 7 0,000 0,03854192 0,10773215 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,03854192 0,10760903 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03854192 0,10748619 ! monocyte differentiation GO:0030224 16 7 0,000 0,03854192 0,10736363 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03854192 0,10724134 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03854192 0,10711934 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03854192 0,10699761 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03854192 0,10687616 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,03854192 0,10675499 ! fibrinolysis GO:0042730 11 7 0,000 0,03854192 0,10663409 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03854192 0,10651346 ! eating behavior GO:0042755 8 7 0,000 0,03854192 0,10639311 ! B cell lineage commitment GO:0002326 21 7 0,000 0,03854192 0,10627302 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03854192 0,10615321 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03854192 0,10603367 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03854192 0,1059144 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03854192 0,10579539 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03854192 0,10567666 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03854192 0,10555818 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03854192 0,10543998 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03854192 0,10532204 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03854192 0,10520436 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03854192 0,10508694 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03854192 0,10496979 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03854192 0,1048529 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03854192 0,10473626 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03854192 0,10461989 ! histone ubiquitination GO:0016574 9 7 0,000 0,03854192 0,10450377 ! regulation of meiosis GO:0040020 12 7 0,000 0,03854192 0,10438792 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03854192 0,10427231 ! T cell lineage commitment GO:0002360 16 7 0,000 0,03854192 0,10415697 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03854192 0,10404188 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03854192 0,10392704 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03854192 0,10381246 ! transcription termination GO:0006353 14 7 0,000 0,03854192 0,10369813 ! anaphase GO:0051322 18 7 0,000 0,03854192 0,10358405 GO:0000090|mitotic anaphase, ! axonal fasciculation GO:0007413 19 7 0,000 0,03854192 0,10347022 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03854192 0,10335664 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03854192 0,10324331 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03854192 0,10313023 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03854192 0,1030174 ! diuresis GO:0030146 12 7 0,000 0,03854192 0,10290481 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03854192 0,10279247 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03854192 0,10268037 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03854192 0,10256852 ! antibiotic transport GO:0042891 9 7 0,000 0,03854192 0,10245691 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03854192 0,10234554 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03854192 0,10223442 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03854192 0,10212354 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03854192 0,10201289 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03854192 0,10190249 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03854192 0,10179232 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03854192 0,1016824 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03854192 0,10157271 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03854192 0,10146325 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03854192 0,10135404 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03854192 0,10124505 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03854192 0,1011363 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03854192 0,10102779 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03854192 0,10091951 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03854192 0,10081146 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03854192 0,10070364 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03854192 0,10059605 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03854192 0,10048869 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03854192 0,10038156 ! muscle adaptation GO:0043500 13 7 0,000 0,03854192 0,10027465 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03854192 0,10016798 ! retina homeostasis GO:0001895 12 7 0,000 0,03854192 0,10006153 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03854192 0,09995531 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03854192 0,09984931 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03854192 0,09974354 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03854192 0,09963799 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,03942166 0,10180456 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,03942166 0,10169706 ! regulation of DNA replication GO:0006275 105 56 1,000 0,03942166 0,10158978 ! chloride transport GO:0006821 102 57 1,000 0,0407079 0,10479388 ! muscle fiber development GO:0048747 131 57 1,000 0,0407079 0,10468357 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,0407079 0,1045735 ! positive regulation of cell migration GO:0030335 137 58 1,000 0,04200984 0,10780465 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,04200984 0,10769153 ! aging GO:0007568 112 58 1,000 0,04200984 0,10757865 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,04200984 0,107466 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,04200984 0,10735359 ! maintenance of location GO:0051235 124 58 1,000 0,04200984 0,10724141 ! establishment of organelle localization GO:0051656 122 59 1,000 0,04332726 0,11048904 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,04392589 0,11189879 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,04392589 0,11178223 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,04392589 0,11166591 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,04392589 0,11154983 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,04392589 0,111434 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,04392589 0,1113184 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,04392589 0,11120305 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,04392589 0,11108793 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,04392589 0,11097305 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,04392589 0,11085841 ! meiotic prophase I GO:0007128 14 8 0,000 0,04392589 0,110744 ! response to zinc ion GO:0010043 12 8 0,000 0,04392589 0,11062983 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,04392589 0,1105159 ! oligopeptide transport GO:0006857 16 8 0,000 0,04392589 0,1104022 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,04392589 0,11028874 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,04392589 0,1101755 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,04392589 0,1100625 ! signal peptide processing GO:0006465 12 8 0,000 0,04392589 0,10994973 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,04392589 0,1098372 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,04392589 0,10972489 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,04392589 0,10961281 ! succinate metabolic process GO:0006105 17 8 0,000 0,04392589 0,10950096 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,04392589 0,10938934 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,04392589 0,10927794 ! estrogen metabolic process GO:0008210 17 8 0,000 0,04392589 0,10916677 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,04392589 0,10905583 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,04392589 0,10894512 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,04392589 0,10883462 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,04392589 0,10872436 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04392589 0,10861431 ! reflex GO:0060004 17 8 0,000 0,04392589 0,10850449 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,04392589 0,10839489 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,04392589 0,10828551 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,04392589 0,10817635 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,04392589 0,10806741 ! pigment granule organization GO:0048753 17 8 0,000 0,04392589 0,10795869 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,04392589 0,10785019 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,04392589 0,10774191 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,04392589 0,10763384 ! astrocyte differentiation GO:0048708 19 8 0,000 0,04392589 0,10752599 ! histidine catabolic process GO:0006548 10 8 0,000 0,04392589 0,10741836 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,04392589 0,10731094 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,04392589 0,10720374 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,04392589 0,10709675 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,04392589 0,10698997 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,04392589 0,10688341 ! melanin metabolic process GO:0006582 17 8 0,000 0,04392589 0,10677705 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,04392589 0,10667091 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,04392589 0,10656498 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,04392589 0,10645927 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,04392589 0,10635376 ! macrophage activation GO:0042116 13 8 0,000 0,04392589 0,10624846 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,04392589 0,10614336 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,04392589 0,10603848 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,04392589 0,1059338 ! purine salvage GO:0043101 12 8 0,000 0,04392589 0,10582933 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,04392589 0,10572506 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,04392589 0,105621 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,04392589 0,10551715 ! osteoblast development GO:0002076 17 8 0,000 0,04392589 0,1054135 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,04392589 0,10531005 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,04392589 0,1052068 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,04392589 0,10510376 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,04392589 0,10500092 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,04392589 0,10489828 ! response to UV-B GO:0010224 17 8 0,000 0,04392589 0,10479584 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,04392589 0,1046936 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,04392589 0,10459156 ! intermediate filament organization GO:0045109 12 8 0,000 0,04392589 0,10448972 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,04392589 0,10438807 ! cellular extravasation GO:0045123 13 8 0,000 0,04392589 0,10428663 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,04392589 0,10418538 ! response to antibiotic GO:0046677 11 8 0,000 0,04392589 0,10408433 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,04392589 0,10398347 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,04392589 0,10388281 ! DNA topological change GO:0006265 12 8 0,000 0,04392589 0,10378234 ! response to tropane GO:0014073 15 8 0,000 0,04392589 0,10368207 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,04392589 0,10358199 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,04392589 0,1034821 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,04392589 0,10338241 ! mast cell activation GO:0045576 14 8 0,000 0,04392589 0,10328291 ! multicellular organismal aging GO:0010259 20 8 0,000 0,04392589 0,1031836 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,04392589 0,10308448 ! gas homeostasis GO:0033483 14 8 0,000 0,04392589 0,10298555 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,04392589 0,10288681 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,04392589 0,10278826 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,04392589 0,10268989 ! nucleosome disassembly GO:0006337 14 8 0,000 0,04392589 0,10259172 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,04392589 0,10249373 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,04392589 0,10239593 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,04392589 0,10229832 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,04392589 0,1022009 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,04392589 0,10210365 ! intracellular lipid transport GO:0032365 16 8 0,000 0,04392589 0,1020066 ! response to tumor cell GO:0002347 16 8 0,000 0,04392589 0,10190972 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,04392589 0,10181304 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of respiratory burst GO:0060263 12 8 0,000 0,04392589 0,10171653 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,04392589 0,10162021 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,04392589 0,10152407 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,04392589 0,10142811 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,04392589 0,10133233 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,04392589 0,10123674 ! hormone catabolic process GO:0042447 17 8 0,000 0,04392589 0,10114132 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,04392589 0,10104608 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,04392589 0,10095103 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,04392589 0,10085615 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,04392589 0,10076145 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,04392589 0,10066692 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,04392589 0,10057258 ! adult feeding behavior GO:0008343 10 8 0,000 0,04392589 0,10047841 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,04392589 0,10038442 ! blastocyst growth GO:0001832 19 8 0,000 0,04392589 0,1002906 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,04392589 0,10019696 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,04392589 0,10010349 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,04392589 0,1000102 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,04392589 0,09991708 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,04392589 0,09982413 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,04392589 0,09973136 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,04392589 0,09963876 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,04392589 0,09954633 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,04392589 0,09945407 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,04392589 0,09936198 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,04392589 0,09927006 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,04392589 0,09917832 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,04392589 0,09908674 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,04392589 0,09899533 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,04392589 0,09890409 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,04392589 0,09881302 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,04392589 0,09872212 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,04392589 0,09863138 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,04392589 0,09854081 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,04392589 0,0984504 ! heterocycle catabolic process GO:0046700 100 60 1,000 0,04465996 0,10000393 ! kidney development GO:0001822 133 60 1,000 0,04465996 0,09991235 ! camera-type eye development GO:0043010 126 61 1,000 0,04600773 0,10283337 ! viral reproductive process GO:0022415 132 62 1,000 0,04737035 0,10578222 ! nucleoside metabolic process GO:0009116 91 62 1,000 0,04737035 0,10568562 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,04737035 0,10558919 ! regulation of mitosis GO:0007088 112 63 1,000 0,04874761 0,10856009 GO:0051783|regulation of nuclear division, ! axon extension GO:0048675 16 9 0,000 0,04927986 0,10964544 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,04927986 0,10954567 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,04927986 0,10944608 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,04927986 0,10934668 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04927986 0,10924745 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,04927986 0,10914841 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,04927986 0,10904954 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,04927986 0,10895085 ! reproductive behavior GO:0019098 22 9 0,000 0,04927986 0,10885234 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04927986 0,10875401 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,04927986 0,10865586 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,04927986 0,10855788 ! UTP metabolic process GO:0046051 10 9 0,000 0,04927986 0,10846008 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,04927986 0,10836246 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,04927986 0,10826501 ! artery development GO:0060840 25 9 0,000 0,04927986 0,10816774 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,04927986 0,10807064 ! regulation of glycolysis GO:0006110 20 9 0,000 0,04927986 0,10797372 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,04927986 0,10787697 ! equilibrioception GO:0050957 20 9 0,000 0,04927986 0,10778039 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,04927986 0,10768398 ! chemosensory behavior GO:0007635 21 9 0,000 0,04927986 0,10758775 ! microtubule bundle formation GO:0001578 22 9 0,000 0,04927986 0,10749169 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,04927986 0,1073958 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04927986 0,10730008 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,04927986 0,10720454 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,04927986 0,10710916 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,04927986 0,10701395 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,04927986 0,10691891 ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04927986 0,10682404 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,04927986 0,10672934 ! protein targeting to ER GO:0045047 25 9 0,000 0,04927986 0,1066348 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,04927986 0,10654044 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,04927986 0,10644624 ! T cell selection GO:0045058 27 9 0,000 0,04927986 0,1063522 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,04927986 0,10625833 ! glycine catabolic process GO:0006546 15 9 0,000 0,04927986 0,10616463 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,04927986 0,1060711 ! endosome organization GO:0007032 20 9 0,000 0,04927986 0,10597772 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04927986 0,10588451 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,04927986 0,10579147 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04927986 0,10569859 ! mannose metabolic process GO:0006013 13 9 0,000 0,04927986 0,10560587 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,04927986 0,10551332 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,04927986 0,10542092 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,04927986 0,10532869 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,04927986 0,10523662 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,04927986 0,10514471 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04927986 0,10505296 ! retinol metabolic process GO:0042572 20 9 0,000 0,04927986 0,10496137 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,04927986 0,10486994 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,04927986 0,10477867 GO:0007351|tripartite regional subdivision, ! macrophage differentiation GO:0030225 15 9 0,000 0,04927986 0,10468756 ! oligodendrocyte development GO:0014003 11 9 0,000 0,04927986 0,10459661 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04927986 0,10450581 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,04927986 0,10441517 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04927986 0,10432469 ! response to amine stimulus GO:0014075 13 9 0,000 0,04927986 0,10423437 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04927986 0,1041442 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,04927986 0,10405419 ! erythrocyte development GO:0048821 17 9 0,000 0,04927986 0,10396433 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,04927986 0,10387463 ! renal water homeostasis GO:0003091 15 9 0,000 0,04927986 0,10378508 ! postreplication repair GO:0006301 25 9 0,000 0,04927986 0,10369569 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,04927986 0,10360645 ! icosanoid secretion GO:0032309 15 9 0,000 0,04927986 0,10351736 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04927986 0,10342843 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,04927986 0,10333965 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,04927986 0,10325102 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,04927986 0,10316255 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04927986 0,10307422 ! sterol catabolic process GO:0016127 14 9 0,000 0,04927986 0,10298605 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,04927986 0,10289803 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,04927986 0,10281016 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,04927986 0,10272243 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,04927986 0,10263486 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,04927986 0,10254744 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,04927986 0,10246016 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,04927986 0,10237304 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,04927986 0,10228606 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,04927986 0,10219923 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04927986 0,10211255 ! purine base metabolic process GO:0006144 25 9 0,000 0,04927986 0,10202601 ! pigment granule transport GO:0051904 17 9 0,000 0,04927986 0,10193962 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,04927986 0,10185338 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,04927986 0,10176728 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04927986 0,10168133 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,04927986 0,10159552 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,04927986 0,10150986 ! mitochondrion localization GO:0051646 18 9 0,000 0,04927986 0,10142434 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 0,05013932 0,10310637 ! positive regulation of cell motion GO:0051272 157 65 1,000 0,05154528 0,10590842 ! regulation of cytokine biosynthetic process GO:0042035 108 66 1,000 0,05296527 0,10873458 ! regulation of lipid metabolic process GO:0019216 132 66 1,000 0,05296527 0,10864328 ! gonad development GO:0008406 115 66 1,000 0,05296527 0,10855214 ! embryonic limb morphogenesis GO:0030326 139 67 1,000 0,0543991 0,11139732 GO:0035113|embryonic appendage morphogenesis, ! chromosome segregation GO:0007059 127 67 1,000 0,0543991 0,11130402 ! myeloid cell differentiation GO:0030099 126 67 1,000 0,0543991 0,11121088 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,054604 0,11153643 ! regulation of developmental growth GO:0048638 16 10 0,000 0,054604 0,11144325 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,054604 0,11135022 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,054604 0,11125735 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,054604 0,11116464 ! associative learning GO:0008306 21 10 0,000 0,054604 0,11107208 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,054604 0,11097967 ! phosphate transport GO:0006817 24 10 0,000 0,054604 0,11088742 ! cell volume homeostasis GO:0006884 17 10 0,000 0,054604 0,11079532 ! CTP metabolic process GO:0046036 11 10 0,000 0,054604 0,11070338 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,054604 0,11061158 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,054604 0,11051994 ! GTP metabolic process GO:0046039 11 10 0,000 0,054604 0,11042845 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,054604 0,11033711 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,054604 0,11024592 ! social behavior GO:0035176 29 10 0,000 0,054604 0,11015489 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,054604 0,110064 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,054604 0,10997326 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,054604 0,10988267 ! androgen metabolic process GO:0008209 17 10 0,000 0,054604 0,10979224 ! phospholipid efflux GO:0033700 19 10 0,000 0,054604 0,10970195 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,054604 0,10961181 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,054604 0,10952181 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,054604 0,10943197 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,054604 0,10934227 ! lung alveolus development GO:0048286 26 10 0,000 0,054604 0,10925272 ! pathogenesis GO:0009405 17 10 0,000 0,054604 0,10916331 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,054604 0,10907405 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,054604 0,10898494 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,054604 0,10889597 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,054604 0,10880715 ! endoderm development GO:0007492 18 10 0,000 0,054604 0,10871847 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,054604 0,10862994 ! arginine catabolic process GO:0006527 17 10 0,000 0,054604 0,10854155 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,054604 0,10845331 ! proline metabolic process GO:0006560 13 10 0,000 0,054604 0,1083652 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,054604 0,10827725 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,054604 0,10818943 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,054604 0,10810176 ! V(D)J recombination GO:0033151 34 10 0,000 0,054604 0,10801422 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,054604 0,10792683 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,054604 0,10783959 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,054604 0,10775248 ! B cell proliferation GO:0042100 19 10 0,000 0,054604 0,10766551 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,054604 0,10757868 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,054604 0,107492 ! multicellular organism growth GO:0035264 19 10 0,000 0,054604 0,10740545 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,054604 0,10731904 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,054604 0,10723277 ! ruffle organization GO:0031529 17 10 0,000 0,054604 0,10714664 ! epithelial cell development GO:0002064 21 10 0,000 0,054604 0,10706065 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,054604 0,10697479 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,054604 0,10688908 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,054604 0,1068035 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,054604 0,10671805 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,054604 0,10663275 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,054604 0,10654758 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,054604 0,10646254 ! copper ion homeostasis GO:0055070 13 10 0,000 0,054604 0,10637765 ! regulation of bone resorption GO:0045124 25 10 0,000 0,054604 0,10629288 ! protein heterooligomerization GO:0051291 17 10 0,000 0,054604 0,10620825 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,054604 0,10612376 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,054604 0,1060394 ! segment specification GO:0007379 15 10 0,000 0,054604 0,10595518 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,054604 0,10587108 ! blastoderm segmentation GO:0007350 19 10 0,000 0,054604 0,10578713 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,054604 0,1057033 ! response to dsRNA GO:0043331 23 10 0,000 0,054604 0,10561961 ! DNA ligation GO:0006266 18 10 0,000 0,054604 0,10553605 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,054604 0,10545262 ! melanosome localization GO:0032400 16 10 0,000 0,054604 0,10536933 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,054604 0,10528616 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,054604 0,10520313 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,054604 0,10512023 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,054604 0,10503745 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,054604 0,10495481 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,054604 0,1048723 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,054604 0,10478992 ! protein sumoylation GO:0016925 17 10 0,000 0,054604 0,10470767 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,054604 0,10462554 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,054604 0,10454355 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,054604 0,10446168 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,054604 0,10437994 ! salivary gland development GO:0007431 28 10 0,000 0,054604 0,10429833 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,054604 0,10421685 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,054604 0,10413549 ! musculoskeletal movement GO:0050881 16 10 0,000 0,054604 0,10405426 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,054604 0,10397316 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,054604 0,10389219 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,054604 0,10381134 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,054604 0,10373061 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,054604 0,10365001 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,054604 0,10356954 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,054604 0,10348919 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,054604 0,10340897 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 0,000 0,054604 0,10332887 GO:0043470|regulation of carbohydrate catabolic process, ! detection of calcium ion GO:0005513 24 10 0,000 0,054604 0,10324889 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,054604 0,10316904 ! blastocyst formation GO:0001825 18 10 0,000 0,054604 0,10308931 ! cerebellar cortex development GO:0021695 16 10 0,000 0,054604 0,1030097 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,054604 0,10293022 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,054604 0,10285086 ! response to nicotine GO:0035094 20 10 0,000 0,054604 0,10277162 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,054604 0,10269251 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,054604 0,10261351 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,05584657 0,10486793 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,05584657 0,10478738 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 1,000 0,05584657 0,10470696 ! viral reproduction GO:0016032 142 68 1,000 0,05584657 0,10462667 ! regulation of lipase activity GO:0060191 137 68 1,000 0,05584657 0,10454649 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,05584657 0,10446644 ! cell projection assembly GO:0030031 138 68 1,000 0,05584657 0,10438651 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,05730749 0,10703532 ! homeostasis of number of cells GO:0048872 131 69 1,000 0,05730749 0,10695355 ! developmental maturation GO:0021700 128 69 1,000 0,05730749 0,10687191 ! urogenital system development GO:0001655 149 69 1,000 0,05730749 0,10679039 ! germ cell development GO:0007281 133 70 1,000 0,05878166 0,10945397 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,05989847 0,11144856 ! respiratory burst GO:0045730 17 11 0,000 0,05989847 0,11136375 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,05989847 0,11127906 ! neuron fate specification GO:0048665 18 11 0,000 0,05989847 0,1111945 ! telencephalon cell migration GO:0022029 23 11 0,000 0,05989847 0,11111007 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,05989847 0,11102577 ! thyroid gland development GO:0030878 26 11 0,000 0,05989847 0,1109416 ! synapsis GO:0007129 14 11 0,000 0,05989847 0,11085755 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,05989847 0,11077363 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,05989847 0,11068984 ! response to pain GO:0048265 27 11 0,000 0,05989847 0,11060617 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,05989847 0,11052263 ! blood vessel remodeling GO:0001974 30 11 0,000 0,05989847 0,11043922 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 0,000 0,05989847 0,11035593 ! bone resorption GO:0045453 16 11 0,000 0,05989847 0,11027277 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,05989847 0,11018973 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05989847 0,11010682 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05989847 0,11002403 ! melanocyte differentiation GO:0030318 20 11 0,000 0,05989847 0,10994137 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,05989847 0,10985883 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,05989847 0,10977642 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,05989847 0,10969413 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,05989847 0,10961196 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,05989847 0,10952991 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,05989847 0,10944799 ! UV protection GO:0009650 20 11 0,000 0,05989847 0,10936619 ! adult heart development GO:0007512 16 11 0,000 0,05989847 0,10928451 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05989847 0,10920296 ! macroautophagy GO:0016236 19 11 0,000 0,05989847 0,10912152 ! temperature homeostasis GO:0001659 18 11 0,000 0,05989847 0,10904021 ! behavioral fear response GO:0001662 27 11 0,000 0,05989847 0,10895902 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,05989847 0,10887795 ! negative regulation of ossification GO:0030279 27 11 0,000 0,05989847 0,108797 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,05989847 0,10871617 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,05989847 0,10863546 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,05989847 0,10855487 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,05989847 0,1084744 ! regulation of organ growth GO:0046620 14 11 0,000 0,05989847 0,10839405 ! pigment granule localization GO:0051875 20 11 0,000 0,05989847 0,10831382 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,05989847 0,1082337 ! vasoconstriction GO:0042310 20 11 0,000 0,05989847 0,10815371 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,05989847 0,10807383 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05989847 0,10799407 ! embryonic axis specification GO:0000578 19 11 0,000 0,05989847 0,10791443 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,05989847 0,1078349 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,05989847 0,1077555 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,05989847 0,10767621 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,05989847 0,10759703 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,05989847 0,10751798 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,05989847 0,10743903 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,05989847 0,10736021 ! prophase GO:0051324 17 11 0,000 0,05989847 0,1072815 ! neuroblast proliferation GO:0007405 25 11 0,000 0,05989847 0,1072029 ! nucleosome positioning GO:0016584 15 11 0,000 0,05989847 0,10712442 ! regulation of isotype switching GO:0045191 24 11 0,000 0,05989847 0,10704606 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,05989847 0,10696781 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,05989847 0,10688967 ! apical protein localization GO:0045176 18 11 0,000 0,05989847 0,10681165 ! acid secretion GO:0046717 20 11 0,000 0,05989847 0,10673375 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05989847 0,10665595 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,05989847 0,10657827 ! positive regulation of leukocyte migration GO:0002687 28 11 0,000 0,05989847 0,1065007 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,05989847 0,10642325 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,05989847 0,1063459 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,05989847 0,10626867 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,05989847 0,10619156 ! cholesterol efflux GO:0033344 21 11 0,000 0,05989847 0,10611455 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05989847 0,10603766 ! oocyte development GO:0048599 20 11 0,000 0,05989847 0,10596087 ! germ cell migration GO:0008354 26 11 0,000 0,05989847 0,1058842 ! embryonic gut development GO:0048566 19 11 0,000 0,05989847 0,10580764 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,05989847 0,10573119 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,05989847 0,10565485 ! activation of innate immune response GO:0002218 16 11 0,000 0,05989847 0,10557862 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,05989847 0,1055025 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,05989847 0,10542649 ! lysogeny GO:0030069 22 11 0,000 0,05989847 0,10535059 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05989847 0,10527479 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,05989847 0,10519911 ! sequestering of metal ion GO:0051238 15 11 0,000 0,05989847 0,10512354 ! regulation of embryonic development GO:0045995 35 11 0,000 0,05989847 0,10504807 ! nucleus localization GO:0051647 22 11 0,000 0,05989847 0,10497271 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,06026889 0,10554617 ! appendage morphogenesis GO:0035107 150 72 1,000 0,06176899 0,10809574 GO:0035108|limb morphogenesis, ! actin filament organization GO:0007015 167 72 1,000 0,06176899 0,10801836 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,06176899 0,1079411 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,06176899 0,10786394 ! appendage development GO:0048736 151 73 1,000 0,06328177 0,11042669 GO:0060173|limb development, ! organelle localization GO:0051640 155 74 1,000 0,06480705 0,11300757 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,06516344 0,11354799 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,06516344 0,11346706 ! positive regulation of cellular catabolic process GO:0031331 34 12 0,000 0,06516344 0,11338624 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,06516344 0,11330554 ! virus-host interaction GO:0019048 30 12 0,000 0,06516344 0,11322496 ! mating GO:0007618 17 12 0,000 0,06516344 0,11314448 ! protein complex disassembly GO:0043241 28 12 0,000 0,06516344 0,11306412 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,06516344 0,11298388 ! hippocampus development GO:0021766 29 12 0,000 0,06516344 0,11290375 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,06516344 0,11282373 ! T cell proliferation GO:0042098 32 12 0,000 0,06516344 0,11274383 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,06516344 0,11266404 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,06516344 0,11258436 ! ventral spinal cord development GO:0021517 25 12 0,000 0,06516344 0,1125048 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,06516344 0,11242534 ! drug transport GO:0015893 16 12 0,000 0,06516344 0,112346 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,06516344 0,11226678 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,06516344 0,11218766 ! polyamine metabolic process GO:0006595 18 12 0,000 0,06516344 0,11210865 ! focal adhesion formation GO:0048041 37 12 0,000 0,06516344 0,11202976 ! mitotic spindle organization GO:0007052 23 12 0,000 0,06516344 0,11195098 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,06516344 0,1118723 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,06516344 0,11179374 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,06516344 0,11171529 ! lipid digestion GO:0044241 21 12 0,000 0,06516344 0,11163695 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,06516344 0,11155872 ! entry into host cell GO:0030260 34 12 0,000 0,06516344 0,11148059 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06516344 0,11140258 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,06516344 0,11132468 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,06516344 0,11124688 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,06516344 0,1111692 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,06516344 0,11109162 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,06516344 0,11101415 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,06516344 0,11093679 ! snRNA metabolic process GO:0016073 30 12 0,000 0,06516344 0,11085953 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,06516344 0,11078239 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,06516344 0,11070535 ! cranial nerve development GO:0021545 23 12 0,000 0,06516344 0,11062841 ! fucose catabolic process GO:0019317 25 12 0,000 0,06516344 0,11055159 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,06516344 0,11047487 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,06516344 0,11039826 ! autonomic nervous system development GO:0048483 24 12 0,000 0,06516344 0,11032175 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,06516344 0,11024535 ! zymogen activation GO:0031638 18 12 0,000 0,06516344 0,11016906 ! T cell homeostasis GO:0043029 28 12 0,000 0,06516344 0,11009287 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,06516344 0,11001679 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,06516344 0,10994081 ! regulation of leukocyte migration GO:0002685 29 12 0,000 0,06516344 0,10986493 ! oocyte differentiation GO:0009994 21 12 0,000 0,06516344 0,10978916 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,06516344 0,1097135 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,06516344 0,10963794 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 0,000 0,06516344 0,10956248 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,06516344 0,10948713 ! defense response to fungus GO:0050832 15 12 0,000 0,06516344 0,10941188 ! embryonic placenta development GO:0001892 21 12 0,000 0,06516344 0,10933674 ! lamellipodium assembly GO:0030032 24 12 0,000 0,06516344 0,10926169 ! response to cold GO:0009409 17 12 0,000 0,06516344 0,10918675 ! establishment of cell polarity GO:0030010 21 12 0,000 0,06516344 0,10911192 ! regulation of synapse organization GO:0050807 18 12 0,000 0,06516344 0,10903718 ! reproductive structure development GO:0048608 131 75 1,000 0,06634462 0,11093766 ! eye development GO:0001654 155 75 1,000 0,06634462 0,11086178 ! axon guidance GO:0007411 162 75 1,000 0,06634462 0,110786 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,06789433 0,11329634 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,06945597 0,11582316 ! regulation of catabolic process GO:0009894 173 77 1,000 0,06945597 0,11574415 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,07039907 0,11723581 ! cGMP metabolic process GO:0046068 18 13 0,000 0,07039907 0,11715595 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,07039907 0,1170762 ! regulation of chemokine production GO:0032642 18 13 0,000 0,07039907 0,11699656 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,07039907 0,11691702 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,07039907 0,11683759 ! peroxisomal transport GO:0043574 28 13 0,000 0,07039907 0,11675827 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,07039907 0,11667906 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,07039907 0,11659996 ! organelle fusion GO:0048284 36 13 0,000 0,07039907 0,11652096 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,07039907 0,11644207 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,07039907 0,11636329 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,07039907 0,11628461 ! endocrine pancreas development GO:0031018 25 13 0,000 0,07039907 0,11620604 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,07039907 0,11612757 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,07039907 0,11604922 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,07039907 0,11597096 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,07039907 0,11589281 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,07039907 0,11581477 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,07039907 0,11573684 ! methionine metabolic process GO:0006555 31 13 0,000 0,07039907 0,115659 ! plasma membrane organization GO:0007009 27 13 0,000 0,07039907 0,11558127 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,07039907 0,11550365 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,07039907 0,11542613 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,07039907 0,11534872 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,07039907 0,11527141 ! cytokine metabolic process GO:0042107 24 13 0,000 0,07039907 0,1151942 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,07039907 0,11511709 ! exocrine system development GO:0035272 34 13 0,000 0,07039907 0,11504009 ! asymmetric protein localization GO:0008105 24 13 0,000 0,07039907 0,11496319 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,07039907 0,1148864 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,07039907 0,1148097 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 0,000 0,07039907 0,11473311 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! L-glutamate transport GO:0015813 30 13 0,000 0,07039907 0,11465662 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,07039907 0,11458024 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,07039907 0,11450395 ! protein homotetramerization GO:0051289 24 13 0,000 0,07039907 0,11442777 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,07039907 0,11435169 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,07039907 0,11427571 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,07039907 0,11419983 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,07039907 0,11412405 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,07039907 0,11404837 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,07039907 0,11397279 ! chromatin silencing GO:0006342 29 13 0,000 0,07039907 0,11389731 ! gland morphogenesis GO:0022612 31 13 0,000 0,07039907 0,11382193 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,07039907 0,11374665 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,07039907 0,11367147 ! regulation of epidermis development GO:0045682 19 13 0,000 0,07039907 0,11359639 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,07039907 0,11352141 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,07039907 0,11344653 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,07039907 0,11337174 ! spleen development GO:0048536 24 13 0,000 0,07039907 0,11329706 ! regulation of mRNA stability GO:0043488 32 13 0,000 0,07039907 0,11322247 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,07039907 0,11314798 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,07039907 0,11307359 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,07039907 0,1129993 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,07039907 0,11292511 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,07039907 0,11285101 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,07039907 0,11277701 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,07039907 0,1127031 ! insulin secretion GO:0030073 24 13 0,000 0,07039907 0,1126293 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,07039907 0,11255559 ! acrosome reaction GO:0007340 19 13 0,000 0,07039907 0,11248197 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,07039907 0,11240846 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,07039907 0,11233503 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,07102937 0,11326681 ! regulation of synaptic transmission GO:0050804 159 79 1,000 0,07261435 0,11571876 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,07421074 0,11818568 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,07421074 0,11810869 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,07421074 0,11803179 ! rRNA transcription GO:0009303 28 14 0,000 0,07560553 0,12017196 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,07560553 0,12009383 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,07560553 0,1200158 ! water transport GO:0006833 21 14 0,000 0,07560553 0,11993786 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,07560553 0,11986003 ! non-recombinational repair GO:0000726 29 14 0,000 0,07560553 0,1197823 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,07560553 0,11970467 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,07560553 0,11962714 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,07560553 0,11954971 ! RNA polyadenylation GO:0043631 32 14 0,000 0,07560553 0,11947239 ! lipid localization GO:0010876 32 14 0,000 0,07560553 0,11939516 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,07560553 0,11931803 ! regulated secretory pathway GO:0045055 24 14 0,000 0,07560553 0,119241 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,07560553 0,11916407 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,07560553 0,11908724 ! arginine metabolic process GO:0006525 21 14 0,000 0,07560553 0,11901051 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,07560553 0,11893388 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,07560553 0,11885734 ! regulation of heart rate GO:0002027 25 14 0,000 0,07560553 0,11878091 ! fear response GO:0042596 34 14 0,000 0,07560553 0,11870457 ! organic alcohol transport GO:0015850 29 14 0,000 0,07560553 0,11862833 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,07560553 0,11855219 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,07560553 0,11847614 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,07560553 0,1184002 ! neutral amino acid transport GO:0015804 28 14 0,000 0,07560553 0,11832435 ! bone mineralization GO:0030282 18 14 0,000 0,07560553 0,1182486 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,07560553 0,11817294 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,07560553 0,11809738 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,07560553 0,11802192 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,07560553 0,11794656 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,07560553 0,11787129 ! regulation of cellular pH GO:0030641 27 14 0,000 0,07560553 0,11779612 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,07560553 0,11772104 ! ribosome assembly GO:0042255 18 14 0,000 0,07560553 0,11764606 ! cerebellum development GO:0021549 23 14 0,000 0,07560553 0,11757117 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,07560553 0,11749638 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,07560553 0,11742168 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,07560553 0,11734708 ! response to gamma radiation GO:0010332 30 14 0,000 0,07560553 0,11727258 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,07560553 0,11719817 ! NADP metabolic process GO:0006739 24 14 0,000 0,07560553 0,11712385 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,07560553 0,11704963 ! oxygen transport GO:0015671 22 14 0,000 0,07560553 0,1169755 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,07560553 0,11690146 ! male genitalia development GO:0030539 26 14 0,000 0,07560553 0,11682752 ! regulation of RNA stability GO:0043487 33 14 0,000 0,07560553 0,11675367 ! regulation of axon extension GO:0030516 43 14 0,000 0,07560553 0,11667992 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,07560553 0,11660626 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,07560553 0,11653269 ! muscle cell differentiation GO:0042692 178 81 1,000 0,07581835 0,11678703 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,07743702 0,11920519 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,07906656 0,12163704 ! inorganic anion transport GO:0015698 156 83 1,000 0,07906656 0,12156049 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,08078297 0,12412126 ! lactation GO:0007595 30 15 0,000 0,08078297 0,12404324 ! reproductive cellular process GO:0048610 22 15 0,000 0,08078297 0,12396533 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,08078297 0,12388751 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,08078297 0,12380979 ! superoxide anion generation GO:0042554 22 15 0,000 0,08078297 0,12373216 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,08078297 0,12365464 ! negative regulation of bone remodeling GO:0046851 34 15 0,000 0,08078297 0,12357721 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,08078297 0,12349987 ! copper ion transport GO:0006825 22 15 0,000 0,08078297 0,12342264 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,08078297 0,1233455 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,08078297 0,12326846 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,08078297 0,12319151 ! sulfate transport GO:0008272 27 15 0,000 0,08078297 0,12311466 ! response to cAMP GO:0051591 25 15 0,000 0,08078297 0,1230379 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,08078297 0,12296125 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,08078297 0,12288468 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,08078297 0,12280821 ! response to hexose stimulus GO:0009746 25 15 0,000 0,08078297 0,12273184 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,08078297 0,12265556 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,08078297 0,12257938 ! vesicle coating GO:0006901 38 15 0,000 0,08078297 0,12250329 ! regulation of exocytosis GO:0017157 26 15 0,000 0,08078297 0,12242729 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,08078297 0,12235139 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,08078297 0,12227559 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,08078297 0,12219988 ! regulation of vasodilation GO:0042312 27 15 0,000 0,08078297 0,12212426 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,08078297 0,12204873 ! histone deacetylation GO:0016575 24 15 0,000 0,08078297 0,1219733 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,08078297 0,12189796 ! water homeostasis GO:0030104 28 15 0,000 0,08078297 0,12182272 ! cofactor transport GO:0051181 30 15 0,000 0,08078297 0,12174756 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,08078297 0,1216725 ! muscle maintenance GO:0046716 26 15 0,000 0,08078297 0,12159753 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,08078297 0,12152266 ! intestinal absorption GO:0050892 31 15 0,000 0,08078297 0,12144788 ! dopamine metabolic process GO:0042417 35 15 0,000 0,08078297 0,12137318 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,08078297 0,12129859 ! heme biosynthetic process GO:0006783 33 15 0,000 0,08078297 0,12122408 ! cell killing GO:0001906 32 15 0,000 0,08078297 0,12114966 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,08078297 0,12107534 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,08078297 0,1210011 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,08078297 0,12092696 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,08078297 0,12085291 ! actin filament polymerization GO:0030041 27 15 0,000 0,08078297 0,12077895 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,08078297 0,12070508 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,08235761 0,12298267 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 0,08235761 0,12290755 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,08235761 0,12283251 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,08401878 0,12523361 ! regulation of lyase activity GO:0051339 169 86 1,000 0,08401878 0,12515725 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,08401878 0,12508098 GO:0002696|positive regulation of leukocyte activation, ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,08593156 0,12785067 ! positive regulation of cell size GO:0045793 29 16 0,000 0,08593156 0,12777285 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,08593156 0,12769513 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,08593156 0,12761751 ! bone remodeling GO:0046849 28 16 0,000 0,08593156 0,12753998 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,08593156 0,12746254 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,08593156 0,12738519 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,08593156 0,12730794 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,08593156 0,12723079 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,08593156 0,12715372 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,08593156 0,12707676 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,08593156 0,12699988 ! startle response GO:0001964 28 16 0,000 0,08593156 0,1269231 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,08593156 0,1268464 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,08593156 0,12676981 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,08593156 0,1266933 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,08593156 0,12661689 ! protein polyubiquitination GO:0000209 41 16 0,000 0,08593156 0,12654057 ! glutamate metabolic process GO:0006536 25 16 0,000 0,08593156 0,12646434 ! pituitary gland development GO:0021983 30 16 0,000 0,08593156 0,1263882 ! response to osmotic stress GO:0006970 27 16 0,000 0,08593156 0,12631215 ! lysosomal transport GO:0007041 31 16 0,000 0,08593156 0,1262362 ! fructose metabolic process GO:0006000 25 16 0,000 0,08593156 0,12616034 ! L-amino acid transport GO:0015807 33 16 0,000 0,08593156 0,12608456 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,08593156 0,12600888 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,08593156 0,12593329 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,08593156 0,12585779 ! negative regulation of immune response GO:0050777 38 16 0,000 0,08593156 0,12578238 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,08593156 0,12570707 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,08593156 0,12563184 ! DNA replication initiation GO:0006270 28 16 0,000 0,08593156 0,1255567 ! neuron recognition GO:0008038 40 16 0,000 0,08593156 0,12548165 ! mRNA splice site selection GO:0006376 44 16 0,000 0,08593156 0,12540669 ! tissue regeneration GO:0042246 27 16 0,000 0,08593156 0,12533182 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,08593156 0,12525704 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,08593156 0,12518235 ! negative regulation of tissue remodeling GO:0034104 37 16 0,000 0,08593156 0,12510775 ! biomineral formation GO:0031214 22 16 0,000 0,08593156 0,12503323 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,08593156 0,12495881 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,08593156 0,12488447 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,08593156 0,12481023 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,08593156 0,12473607 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,08593156 0,12466199 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,08593156 0,12458801 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,08593156 0,12451412 ! peptide hormone processing GO:0016486 27 16 0,000 0,08593156 0,12444031 ! one-carbon metabolic process GO:0006730 167 88 1,000 0,08737157 0,12645067 ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,08906286 0,12882212 ! regulation of neurological system process GO:0031644 175 89 1,000 0,08906286 0,12874589 ! response to unfolded protein GO:0006986 139 90 1,000 0,09076386 0,13112721 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,09105145 0,13146495 ! metencephalon development GO:0022037 32 17 0,000 0,09105145 0,1313873 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,09105145 0,13130974 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,09105145 0,13123227 ! filopodium assembly GO:0046847 42 17 0,000 0,09105145 0,1311549 ! endothelial cell migration GO:0043542 31 17 0,000 0,09105145 0,13107761 ! gene silencing by RNA GO:0031047 38 17 0,000 0,09105145 0,13100041 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,09105145 0,13092331 ! glial cell development GO:0021782 28 17 0,000 0,09105145 0,1308463 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,09105145 0,13076937 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,09105145 0,13069254 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,09105145 0,1306158 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,09105145 0,13053914 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,09105145 0,13046258 ! myoblast differentiation GO:0045445 50 17 0,000 0,09105145 0,13038611 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,09105145 0,13030973 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 0,000 0,09105145 0,13023343 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,09105145 0,13015723 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,09105145 0,13008111 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,09105145 0,13000509 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,09105145 0,12992915 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,09105145 0,1298533 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,09105145 0,12977754 ! membrane budding GO:0006900 42 17 0,000 0,09105145 0,12970187 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,09105145 0,12962628 ! regulation of protein binding GO:0043393 33 17 0,000 0,09105145 0,12955079 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,09105145 0,12947538 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,09105145 0,12940006 ! genitalia development GO:0048806 32 17 0,000 0,09105145 0,12932483 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,09105145 0,12924968 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,09105145 0,12917462 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,09105145 0,12909965 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,09105145 0,12902477 ! steroid catabolic process GO:0006706 34 17 0,000 0,09105145 0,12894997 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,09105145 0,12887526 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,09105145 0,12880064 ! gas transport GO:0015669 26 17 0,000 0,09105145 0,1287261 ! organic cation transport GO:0015695 32 17 0,000 0,09105145 0,12865165 ! negative regulation of homeostatic process GO:0032845 36 17 0,000 0,09105145 0,12857728 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,09105145 0,12850301 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,09105145 0,12842881 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,09247442 0,13036065 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! gland development GO:0048732 220 91 1,000 0,09247442 0,13028548 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,09592357 0,13506702 GO:0010498|proteasomal protein catabolic process, ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,09614281 0,13529775 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,09614281 0,13521986 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,09614281 0,13514206 ! limbic system development GO:0021761 40 18 0,000 0,09614281 0,13506434 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,09614281 0,13498672 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,09614281 0,13490919 ! adult walking behavior GO:0007628 36 18 0,000 0,09614281 0,13483174 ! patterning of blood vessels GO:0001569 43 18 0,000 0,09614281 0,13475439 ! heart looping GO:0001947 34 18 0,000 0,09614281 0,13467712 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,09614281 0,13459994 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,09614281 0,13452285 ! centrosome cycle GO:0007098 26 18 0,000 0,09614281 0,13444585 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,09614281 0,13436893 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,09614281 0,13429211 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,09614281 0,13421537 ! glycine metabolic process GO:0006544 30 18 0,000 0,09614281 0,13413872 ! glutamine metabolic process GO:0006541 29 18 0,000 0,09614281 0,13406215 ! response to retinoic acid GO:0032526 31 18 0,000 0,09614281 0,13398568 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,09614281 0,13390929 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,09614281 0,13383299 ! DNA integration GO:0015074 32 18 0,000 0,09614281 0,13375677 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,09614281 0,13368065 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,09614281 0,1336046 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,09614281 0,13352865 ! neural crest cell migration GO:0001755 41 18 0,000 0,09614281 0,13345278 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,09614281 0,133377 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,09614281 0,1333013 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,09614281 0,13322569 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,09614281 0,13315017 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,09614281 0,13307473 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,09614281 0,13299937 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 0,000 0,09614281 0,13292411 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,09614281 0,13284892 ! detection of bacterium GO:0016045 22 18 0,000 0,09614281 0,13277382 ! nerve development GO:0021675 34 18 0,000 0,09614281 0,13269881 ! defense response to virus GO:0051607 43 18 0,000 0,09614281 0,13262388 ! microspike assembly GO:0030035 46 18 0,000 0,09614281 0,13254904 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,09614281 0,13247428 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,09614281 0,1323996 ! regulation of membrane potential GO:0042391 179 94 1,000 0,09766185 0,13441571 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,09940905 0,13674342 ! response to protein stimulus GO:0051789 158 96 1,000 0,10116503 0,13908056 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,1012058 0,13905836 ! positive regulation of translation GO:0045727 31 19 0,000 0,1012058 0,13898019 ! negative regulation of defense response GO:0031348 27 19 0,000 0,1012058 0,13890212 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,1012058 0,13882412 ! neuron maturation GO:0042551 46 19 0,000 0,1012058 0,13874622 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,1012058 0,13866841 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,1012058 0,13859068 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,1012058 0,13851303 GO:0019692|deoxyribose phosphate metabolic process, ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,1012058 0,13843548 ! inositol metabolic process GO:0006020 33 19 0,000 0,1012058 0,13835801 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,1012058 0,13828063 ! memory GO:0007613 34 19 0,000 0,1012058 0,13820333 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,1012058 0,13812613 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,1012058 0,138049 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,1012058 0,13797197 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,1012058 0,13789502 ! cerebral cortex development GO:0021987 40 19 0,000 0,1012058 0,13781815 ! pigmentation during development GO:0048066 42 19 0,000 0,1012058 0,13774137 ! response to vitamin A GO:0033189 32 19 0,000 0,1012058 0,13766468 ! heme metabolic process GO:0042168 40 19 0,000 0,1012058 0,13758807 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,1012058 0,13751155 ! regulation of endothelial cell migration GO:0010594 45 19 0,000 0,1012058 0,13743511 ! response to fungus GO:0009620 26 19 0,000 0,1012058 0,13735876 ! peptide cross-linking GO:0018149 39 19 0,000 0,1012058 0,13728249 ! protein export from nucleus GO:0006611 40 19 0,000 0,1012058 0,13720631 ! heart process GO:0003015 32 19 0,000 0,1012058 0,13713021 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,1012058 0,13705419 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,1012058 0,13697826 ! visual learning GO:0008542 38 19 0,000 0,1012058 0,13690242 ! cellular pigmentation GO:0033059 37 19 0,000 0,1012058 0,13682666 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,1012058 0,13675098 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,1012058 0,13667538 ! vitamin transport GO:0051180 31 19 0,000 0,1012058 0,13659987 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,1012058 0,13652444 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,1012058 0,1364491 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,1012058 0,13637384 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,1012058 0,13629866 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,1012058 0,13622356 ! cilium assembly GO:0042384 38 19 0,000 0,1012058 0,13614855 ! peptide hormone secretion GO:0030072 32 19 0,000 0,1012058 0,13607362 ! transcription initiation GO:0006352 171 97 1,000 0,10292963 0,13831522 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,1047027 0,1406205 ! protein secretion GO:0009306 45 20 0,000 0,10624056 0,14260753 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,10624056 0,14252921 ! positive regulation of ossification GO:0045778 50 20 0,000 0,10624056 0,14245099 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,10624056 0,14237285 ! skin development GO:0043588 42 20 0,000 0,10624056 0,14229479 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,10624056 0,14221682 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,10624056 0,14213894 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,10624056 0,14206114 ! response to vitamin GO:0033273 36 20 0,000 0,10624056 0,14198342 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,10624056 0,14190579 ! regulation of carbohydrate metabolic process GO:0006109 37 20 0,000 0,10624056 0,14182825 GO:0010675|regulation of cellular carbohydrate metabolic process, ! forelimb morphogenesis GO:0035136 35 20 0,000 0,10624056 0,14175079 ! bile acid metabolic process GO:0008206 34 20 0,000 0,10624056 0,14167342 ! retinoid metabolic process GO:0001523 34 20 0,000 0,10624056 0,14159613 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,10624056 0,14151892 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,10624056 0,1414418 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,10624056 0,14136476 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,10624056 0,14128781 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,10624056 0,14121093 ! body fluid secretion GO:0007589 33 20 0,000 0,10624056 0,14113415 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,10624056 0,14105744 ! peptide secretion GO:0002790 38 20 0,000 0,10624056 0,14098082 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,10624056 0,14090429 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,10624056 0,14082783 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,10624056 0,14075146 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,10624056 0,14067518 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,10624056 0,14059897 ! cell-cell junction organization GO:0045216 43 20 0,000 0,10624056 0,14052285 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,10624056 0,14044681 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,10624056 0,14037085 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,10624056 0,14029497 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,10624056 0,14021918 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,10624056 0,14014347 ! negative regulation of translation GO:0017148 32 20 0,000 0,10624056 0,14006784 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,10624056 0,13999229 ! regulation of cell killing GO:0031341 46 21 0,000 0,11124727 0,14651055 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,11124727 0,14643161 ! hormone secretion GO:0046879 39 21 0,000 0,11124727 0,14635276 ! cAMP metabolic process GO:0046058 41 21 0,000 0,11124727 0,14627399 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,11124727 0,14619531 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,11124727 0,14611671 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,11124727 0,14603819 ! ovarian follicle development GO:0001541 39 21 0,000 0,11124727 0,14595976 ! smooth muscle contraction GO:0006939 48 21 0,000 0,11124727 0,14588141 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,11124727 0,14580315 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,11124727 0,14572497 ! plasma membrane fusion GO:0045026 33 21 0,000 0,11124727 0,14564688 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,11124727 0,14556887 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,11124727 0,14549094 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,11124727 0,14541309 ! sensory perception of pain GO:0019233 33 21 0,000 0,11124727 0,14533533 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,11124727 0,14525766 ! diencephalon development GO:0021536 36 21 0,000 0,11124727 0,14518006 ! collagen fibril organization GO:0030199 62 21 0,000 0,11124727 0,14510255 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,11124727 0,14502512 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,11124727 0,14494777 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,11124727 0,14487051 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,11124727 0,14479333 ! collagen catabolic process GO:0030574 29 21 0,000 0,11124727 0,14471623 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,11124727 0,14463921 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,11124727 0,14456227 ! sperm-egg recognition GO:0035036 23 21 0,000 0,11124727 0,14448542 ! actin filament-based movement GO:0030048 47 21 0,000 0,11124727 0,14440865 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,11124727 0,14433196 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,11622606 0,1507114 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,11622606 0,15063145 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,11622606 0,15055158 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,11622606 0,15047179 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,11622606 0,15039209 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,11622606 0,15031248 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,11622606 0,15023295 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,11622606 0,1501535 ! vacuolar transport GO:0007034 41 22 0,000 0,11622606 0,15007414 ! central nervous system neuron development GO:0021954 47 22 0,000 0,11622606 0,14999486 ! fucose metabolic process GO:0006004 44 22 0,000 0,11622606 0,14991567 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,11622606 0,14983656 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,11622606 0,14975753 ! ureteric bud development GO:0001657 50 22 0,000 0,11622606 0,14967858 ! cell aging GO:0007569 48 22 0,000 0,11622606 0,14959972 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,11622606 0,14952095 ! cytolysis GO:0019835 27 22 0,000 0,11622606 0,14944225 ! renal system process GO:0003014 42 22 0,000 0,11622606 0,14936364 ! vasodilation GO:0042311 40 22 0,000 0,11622606 0,14928511 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,11622606 0,14920666 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,11622606 0,1491283 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,11622606 0,14905001 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,11622606 0,14897181 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,11622606 0,14889369 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,11622606 0,14881566 ! sarcomere organization GO:0045214 32 22 0,000 0,11622606 0,1487377 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,11622606 0,14865983 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,11622606 0,14858204 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,11622606 0,14850433 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,11622606 0,1484267 ! gut development GO:0048565 44 22 0,000 0,11622606 0,14834915 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,11622606 0,14827168 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,12117711 0,15450714 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,12117711 0,15442654 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,12117711 0,15434603 ! gluconeogenesis GO:0006094 38 23 0,000 0,12117711 0,1542656 ! glycerol metabolic process GO:0006071 40 23 0,000 0,12117711 0,15418525 ! viral genome replication GO:0019079 44 23 0,000 0,12117711 0,15410499 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,12117711 0,15402481 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,12117711 0,15394471 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,12117711 0,1538647 ! regeneration GO:0031099 42 23 0,000 0,12117711 0,15378477 ! axis specification GO:0009798 43 23 0,000 0,12117711 0,15370492 ! visual behavior GO:0007632 46 23 0,000 0,12117711 0,15362516 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,12117711 0,15354548 ! response to ethanol GO:0045471 47 23 0,000 0,12117711 0,15346588 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,12117711 0,15338636 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,12117711 0,15330693 ! peroxisome organization GO:0007031 43 23 0,000 0,12117711 0,15322758 ! lysosome organization GO:0007040 47 23 0,000 0,12117711 0,15314831 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,12117711 0,15306912 ! vesicle targeting GO:0006903 49 23 0,000 0,12117711 0,15299001 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,12117711 0,15291099 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,12117711 0,15283205 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,12117711 0,15275319 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,12117711 0,15267441 ! DNA modification GO:0006304 36 23 0,000 0,12117711 0,15259571 ! fatty acid transport GO:0015908 47 23 0,000 0,12117711 0,15251709 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,12117711 0,15243856 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,12117711 0,1523601 ! hormone transport GO:0009914 41 23 0,000 0,12117711 0,15228173 ! cell-cell recognition GO:0009988 28 23 0,000 0,12117711 0,15220343 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,12117711 0,15212522 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,12117711 0,15204709 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,12117711 0,15196903 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,12610056 0,15806242 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,12610056 0,15798136 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 55 24 0,000 0,12610056 0,15790039 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,12610056 0,1578195 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,12610056 0,15773869 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,12610056 0,15765796 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,12610056 0,15757732 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,12610056 0,15749676 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,12610056 0,15741628 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,12610056 0,15733588 ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,12610056 0,15725557 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,12610056 0,15717534 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,12610056 0,15709519 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,12610056 0,15701512 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,12610056 0,15693513 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,12610056 0,15685522 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,12610056 0,1567754 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,12610056 0,15669566 ! membrane depolarization GO:0051899 45 24 0,000 0,12610056 0,15661599 ! pallium development GO:0021543 56 24 0,000 0,12610056 0,15653641 ! oogenesis GO:0048477 44 24 0,000 0,12610056 0,15645691 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,12610056 0,15637749 ! platelet activation GO:0030168 41 24 0,000 0,12610056 0,15629815 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,12610056 0,15621889 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,12610056 0,15613972 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,12610056 0,15606062 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,12610056 0,1559816 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,12610056 0,15590266 ! regulation of amine transport GO:0051952 41 24 0,000 0,12610056 0,1558238 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,13099656 0,16179201 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,13099656 0,16171025 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,13099656 0,16162858 ! leukocyte adhesion GO:0007159 55 25 0,000 0,13099656 0,16154699 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,13099656 0,16146548 ! phototransduction GO:0007602 37 25 0,000 0,13099656 0,16138406 ! keratinization GO:0031424 37 25 0,000 0,13099656 0,16130272 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,13099656 0,16122146 ! vacuole organization GO:0007033 49 25 0,000 0,13099656 0,16114028 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,13099656 0,16105918 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,13099656 0,16097816 ! chromosome condensation GO:0030261 48 25 0,000 0,13099656 0,16089723 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,13099656 0,16081638 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,13099656 0,16073561 ! interaction with host GO:0051701 66 25 0,000 0,13099656 0,16065491 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,13099656 0,16057431 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,13099656 0,16049378 ! immunoglobulin production GO:0002377 62 25 0,000 0,13099656 0,16041333 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,13099656 0,16033296 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,13099656 0,16025267 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,13099656 0,16017247 ! liver development GO:0001889 55 25 0,000 0,13099656 0,16009234 ! protein tetramerization GO:0051262 57 25 0,000 0,13099656 0,1600123 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,13586527 0,16587649 ! initiation of viral infection GO:0019059 60 26 0,000 0,13586527 0,16579363 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,13586527 0,16571086 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,13586527 0,16562817 ! molting cycle process GO:0022404 52 26 0,000 0,13586527 0,16554556 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,13586527 0,16546303 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,13586527 0,16538059 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,13586527 0,16529823 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,13586527 0,16521595 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,13586527 0,16513375 ! digestive system process GO:0022600 49 26 0,000 0,13586527 0,16505164 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,13586527 0,16496961 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 0,000 0,13586527 0,16488765 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,13586527 0,16480578 ! osteoblast differentiation GO:0001649 63 26 0,000 0,13586527 0,16472399 ! neural crest cell development GO:0014032 59 26 0,000 0,13586527 0,16464229 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,13586527 0,16456066 ! negative regulation of cell development GO:0010721 83 26 0,000 0,13586527 0,16447911 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,13586527 0,16439765 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,13586527 0,16431626 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,13586527 0,16423496 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,13586527 0,16415373 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,13586527 0,16407259 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,13586527 0,16399153 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,13586527 0,16391054 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,13586527 0,16382964 ! blastocyst development GO:0001824 50 26 0,000 0,13586527 0,16374881 ! telomere organization GO:0032200 46 26 0,000 0,13586527 0,16366807 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,13586527 0,16358741 ! neural tube closure GO:0001843 58 26 0,000 0,13586527 0,16350682 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,13586527 0,16342632 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,13586527 0,16334589 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,13586527 0,16326554 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,14070684 0,16900039 ! embryonic pattern specification GO:0009880 49 27 0,000 0,14070684 0,16891735 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,14070684 0,16883438 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,14070684 0,1687515 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,14070684 0,16866869 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,14070684 0,16858597 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,14070684 0,16850333 ! iron ion transport GO:0006826 65 27 0,000 0,14070684 0,16842077 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,14070684 0,16833829 ! superoxide metabolic process GO:0006801 41 27 0,000 0,14070684 0,1682559 ! tube lumen formation GO:0035148 59 27 0,000 0,14070684 0,16817358 ! regulation of endothelial cell proliferation GO:0001936 60 27 0,000 0,14070684 0,16809134 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,14070684 0,16800919 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,14070684 0,16792711 ! response to toxin GO:0009636 49 27 0,000 0,14070684 0,16784512 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,14070684 0,1677632 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,14070684 0,16768136 ! leukocyte proliferation GO:0070661 59 27 0,000 0,14070684 0,16759961 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,14552141 0,17324991 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,14552141 0,17316552 ! vesicle docking GO:0048278 55 28 0,000 0,14552141 0,17308121 ! circadian rhythm GO:0007623 56 28 0,000 0,14552141 0,17299699 ! dendrite development GO:0016358 67 28 0,000 0,14552141 0,17291285 ! fat cell differentiation GO:0045444 57 28 0,000 0,14552141 0,17282878 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,14552141 0,17274481 ! sperm motility GO:0030317 37 28 0,000 0,14552141 0,17266091 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,14552141 0,17257709 ! base-excision repair GO:0006284 41 28 0,000 0,14552141 0,17249336 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,14552141 0,1724097 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,14552141 0,17232613 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,14552141 0,17224264 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,14552141 0,17215923 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,14552141 0,1720759 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,14552141 0,17199265 ! peptidyl-tyrosine modification GO:0018212 57 28 0,000 0,14552141 0,17190948 ! glutathione metabolic process GO:0006749 42 28 0,000 0,14552141 0,17182639 ! lipid oxidation GO:0034440 48 28 0,000 0,14552141 0,17174339 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,14552141 0,17166046 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,14552141 0,17157761 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 0,000 0,15030915 0,17713712 ! translational initiation GO:0006413 66 29 0,000 0,15030915 0,17705171 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,15030915 0,17696639 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,15030915 0,17688114 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,15030915 0,17679598 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,15030915 0,1767109 ! primary neural tube formation GO:0014020 61 29 0,000 0,15030915 0,1766259 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,15030915 0,17654099 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,15030915 0,17645615 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,15030915 0,1763714 ! synaptogenesis GO:0007416 46 29 0,000 0,15030915 0,17628673 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,15030915 0,17620214 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,15030915 0,17611763 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,15030915 0,1760332 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,15030915 0,17594885 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,15507019 0,1814351 ! phenol metabolic process GO:0018958 56 30 0,000 0,15507019 0,18134824 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,15507019 0,18126147 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,15507019 0,18117479 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,15507019 0,18108818 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,15507019 0,18100166 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,15507019 0,18091522 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,15507019 0,18082887 ! acute-phase response GO:0006953 50 30 0,000 0,15507019 0,1807426 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,15507019 0,1806564 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,15507019 0,1805703 ! myofibril assembly GO:0030239 50 30 0,000 0,15507019 0,18048427 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,15507019 0,18039832 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,15507019 0,18031246 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,15507019 0,18022668 ! cell fate determination GO:0001709 64 30 0,000 0,15507019 0,18014098 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,15507019 0,18005536 ! phospholipid transport GO:0015914 65 30 0,000 0,15507019 0,17996982 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,15507019 0,17988437 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,15507019 0,17979899 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,15507019 0,1797137 ! tissue homeostasis GO:0001894 50 30 0,000 0,15507019 0,17962849 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 52 30 0,000 0,15507019 0,17954336 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,15980469 0,18493741 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,15980469 0,18484984 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,15980469 0,18476236 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,15980469 0,18467496 ! cell junction assembly GO:0034329 85 31 0,000 0,15980469 0,18458764 ! regulation of innate immune response GO:0045088 57 31 0,000 0,15980469 0,18450041 ! ovulation cycle process GO:0022602 55 31 0,000 0,15980469 0,18441326 ! peptide transport GO:0015833 60 31 0,000 0,15980469 0,18432619 ! detection of light stimulus GO:0009583 44 31 0,000 0,15980469 0,1842392 ! natural killer cell activation GO:0030101 50 31 0,000 0,15980469 0,18415229 ! cofactor catabolic process GO:0051187 54 31 0,000 0,15980469 0,18406547 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,15980469 0,18397873 ! eye morphogenesis GO:0048592 65 31 0,000 0,15980469 0,18389207 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,15980469 0,18380549 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,1645128 0,18913165 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,1645128 0,18904269 ! collagen metabolic process GO:0032963 49 32 0,000 0,1645128 0,18895381 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,1645128 0,18886502 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,1645128 0,18877631 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,1645128 0,18868768 ! muscle cell development GO:0055001 52 32 0,000 0,1645128 0,18859914 ! mesoderm formation GO:0001707 73 32 0,000 0,1645128 0,18851068 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,1645128 0,1884223 ! ovulation cycle GO:0042698 57 32 0,000 0,1645128 0,188334 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,1645128 0,18824579 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,1645128 0,18815766 ! positive regulation of catabolic process GO:0009896 72 32 0,000 0,1645128 0,18806961 ! gene silencing GO:0016458 71 32 0,000 0,1645128 0,18798165 ! regulation of pH GO:0006885 56 33 0,000 0,16919465 0,19324101 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,16919465 0,19315071 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,16919465 0,1930605 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,16919465 0,19297037 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,16919465 0,19288032 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,16919465 0,19279036 ! response to ionizing radiation GO:0010212 74 33 0,000 0,16919465 0,19270048 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,16919465 0,19261068 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,16919465 0,19252097 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,16919465 0,19243134 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,16919465 0,1923418 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,16919465 0,19225234 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,1738504 0,19745073 ! post-embryonic development GO:0009791 76 34 0,000 0,1738504 0,19735898 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,1738504 0,19726731 ! cholesterol transport GO:0030301 62 34 0,000 0,1738504 0,19717573 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,1738504 0,19708423 ! spliceosome assembly GO:0000245 75 34 0,000 0,1738504 0,19699282 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,1738504 0,19690149 ! formation of primary germ layer GO:0001704 76 34 0,000 0,1738504 0,19681025 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,1738504 0,19671909 ! adult locomotory behavior GO:0008344 62 34 0,000 0,1738504 0,19662802 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 0,000 0,1738504 0,19653703 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,17848018 0,20167765 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,17848018 0,20158442 ! negative regulation of secretion GO:0051048 68 35 0,000 0,17848018 0,20149126 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,17848018 0,20139819 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,17848018 0,20130521 ! membrane docking GO:0022406 69 35 0,000 0,17848018 0,20121232 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,17848018 0,20111951 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,17848018 0,20102678 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,17848018 0,20093414 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,17848018 0,20084159 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,17848018 0,20074912 ! ceramide metabolic process GO:0006672 72 35 0,000 0,17848018 0,20065674 ! telencephalon development GO:0021537 81 35 0,000 0,17848018 0,20056444 ! sterol transport GO:0015918 63 35 0,000 0,17848018 0,20047223 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,17848018 0,2003801 ! placenta development GO:0001890 53 35 0,000 0,17848018 0,20028805 ! vesicle localization GO:0051648 70 35 0,000 0,17848018 0,20019609 ! regulation of muscle development GO:0048634 82 36 0,000 0,18308416 0,20526599 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,18308416 0,20517183 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,18308416 0,20507776 ! positive regulation of cell development GO:0010720 85 36 0,000 0,18308416 0,20498377 ! protein targeting to membrane GO:0006612 75 36 0,000 0,18308416 0,20488987 ! regulation of proteolysis GO:0030162 77 36 0,000 0,18308416 0,20479606 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,18308416 0,20470233 ! aerobic respiration GO:0009060 56 36 0,000 0,18308416 0,20460869 ! cytokine production GO:0001816 68 36 0,000 0,18308416 0,20451513 ! embryonic organ development GO:0048568 67 36 0,000 0,18308416 0,20442166 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,18308416 0,20432827 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,18308416 0,20423497 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 0,000 0,18766246 0,20924664 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,18766246 0,20915118 ! actomyosin structure organization GO:0031032 68 37 0,000 0,18766246 0,2090558 ! cell junction organization GO:0034330 96 37 0,000 0,18766246 0,20896052 ! tissue remodeling GO:0048771 78 37 0,000 0,18766246 0,20886532 ! female gonad development GO:0008585 71 37 0,000 0,18766246 0,20877021 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,18766246 0,20867518 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,19221522 0,21364049 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,19221522 0,21354334 ! organic anion transport GO:0015711 82 38 0,000 0,19221522 0,21344627 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,19221522 0,21334929 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,19221522 0,2132524 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,19221522 0,2131556 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,19221522 0,21305889 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,19221522 0,21296226 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,19221522 0,21286573 ! spermatid development GO:0007286 69 38 0,000 0,19221522 0,21276928 ! pigment metabolic process GO:0042440 87 38 0,000 0,19221522 0,21267291 ! neural tube formation GO:0001841 79 38 0,000 0,19221522 0,21257664 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,19674261 0,21748515 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,19674261 0,21738679 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,19674261 0,21728851 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,19674261 0,21719032 ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,19674261 0,21709222 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,20124474 0,22195977 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,20124474 0,22185961 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,20124474 0,22175954 GO:0046660|female sex differentiation, ! mismatch repair GO:0006298 58 40 0,000 0,20124474 0,22165956 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,20124474 0,22155966 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,20124474 0,22145986 ! RNA export from nucleus GO:0006405 61 41 0,000 0,20572176 0,22628468 ! mRNA catabolic process GO:0006402 79 41 0,000 0,20572176 0,22618284 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,20572176 0,22608109 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,20572176 0,22597944 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,20572176 0,22587787 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,20572176 0,2257764 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,20572176 0,22567502 ! feeding behavior GO:0007631 69 41 0,000 0,20572176 0,22557373 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,20572176 0,22547253 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,20572176 0,22537142 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,20572176 0,2252704 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,20572176 0,22516947 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,20572176 0,22506864 ! RNA modification GO:0009451 64 41 0,000 0,20572176 0,22496789 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,21017382 0,22973362 ! organic ether metabolic process GO:0018904 59 42 0,000 0,21017382 0,22963088 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,21017382 0,22952823 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,21017382 0,22942567 ! regulation of protein secretion GO:0050708 77 42 0,000 0,21017382 0,2293232 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,21017382 0,22922082 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,21017382 0,22911854 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,21460105 0,23384048 ! regulation of tube size GO:0035150 76 43 0,000 0,21460105 0,23373623 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,21460105 0,23363207 ! glucose transport GO:0015758 66 43 0,000 0,21460105 0,233528 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,21460105 0,23342402 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,21460105 0,23332014 ! ion transmembrane transport GO:0034220 79 43 0,000 0,21460105 0,23321635 ! neuron migration GO:0001764 85 43 0,000 0,21460105 0,23311265 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,21900358 0,23778922 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,21900358 0,23768358 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,21900358 0,23757804 ! hexose transport GO:0008645 68 44 0,000 0,21900358 0,23747259 GO:0015749|monosaccharide transport, ! striated muscle contraction GO:0006941 85 44 0,000 0,21900358 0,23736724 ! phagocytosis GO:0006909 105 44 0,000 0,21900358 0,23726197 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,21900358 0,2371568 ! double-strand break repair GO:0006302 85 44 0,000 0,21900358 0,23705173 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,22338156 0,24168342 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,22338156 0,24157643 ! keratinocyte differentiation GO:0030216 81 45 0,000 0,22338156 0,24146954 ! B cell differentiation GO:0030183 124 45 0,000 0,22338156 0,24136274 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,22338156 0,24125604 ! female gamete generation GO:0007292 71 45 0,000 0,22338156 0,24114943 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,22338156 0,24104291 ! polyol metabolic process GO:0019751 77 45 0,000 0,22338156 0,24093649 ! developmental growth GO:0048589 88 45 0,000 0,22338156 0,24083017 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,22773512 0,24541548 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,22773512 0,24530728 ! glycolysis GO:0006096 71 46 0,000 0,22773512 0,24519916 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,22773512 0,24509115 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,22773512 0,24498323 ! neural tube development GO:0021915 91 47 0,000 0,2320644 0,24953052 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,2320644 0,24942073 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,23636953 0,25393613 ! mitochondrial transport GO:0006839 94 48 0,000 0,23636953 0,25382451 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,23636953 0,25371299 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,23636953 0,25360156 ! vascular process in circulatory system GO:0003018 85 48 0,000 0,23636953 0,25349024 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,23636953 0,25337901 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,23636953 0,25326788 ! response to calcium ion GO:0051592 94 49 0,000 0,24065065 0,25774201 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,24065065 0,25762907 ! JNK cascade GO:0007254 106 49 0,000 0,24065065 0,25751622 ! protein homooligomerization GO:0051260 84 49 0,000 0,24065065 0,25740347 ! regulation of ion transport GO:0043269 86 50 0,000 0,24490788 0,26184243 ! endocrine system development GO:0035270 109 50 0,000 0,24490788 0,26172789 ! regulation of ossification GO:0030278 123 50 0,000 0,24490788 0,26161345 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,24490788 0,2614991 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,24490788 0,26138486 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,24490788 0,26127072 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,24490788 0,26115668 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,24490788 0,26104274 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,24914136 0,26543932 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,24914136 0,26532361 ! peptide metabolic process GO:0006518 80 51 0,000 0,24914136 0,265208 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,25335123 0,26957189 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,25335123 0,26945453 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,25335123 0,26933728 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,25335123 0,26922012 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,25335123 0,26910307 ! excretion GO:0007588 87 52 0,000 0,25335123 0,26898612 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,25335123 0,26886927 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,25335123 0,26875252 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,25335123 0,26863588 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,25335123 0,26851933 ! amino acid activation GO:0043038 98 52 0,000 0,25335123 0,26840289 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! positive regulation of growth GO:0045927 96 53 0,000 0,25753762 0,27271972 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,25753762 0,27260156 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,25753762 0,2724835 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,26170064 0,27676826 ! neuromuscular process GO:0050905 107 54 0,000 0,26170064 0,2766485 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,26170064 0,27652884 ! membrane fusion GO:0006944 122 54 0,000 0,26170064 0,27640928 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,26170064 0,27628983 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,26170064 0,27617049 ! regulation of cell shape GO:0008360 142 54 0,000 0,26170064 0,27605124 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,26170064 0,2759321 ! RNA catabolic process GO:0006401 103 55 0,000 0,26584045 0,2801761 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,26584045 0,28005529 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,26584045 0,27993457 ! cell recognition GO:0008037 98 55 0,000 0,26584045 0,27981396 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,26584045 0,27969346 ! cell maturation GO:0048469 107 55 0,000 0,26584045 0,27957306 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,26584045 0,27945276 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,26584045 0,27933256 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,26995715 0,28353625 ! glucose catabolic process GO:0006007 88 56 0,000 0,26995715 0,2834144 ! RNA elongation GO:0006354 90 56 0,000 0,26995715 0,28329266 ! regulation of bone remodeling GO:0046850 143 57 0,000 0,27405089 0,28746514 ! heart morphogenesis GO:0003007 105 57 0,000 0,27405089 0,28734177 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,27405089 0,2872185 ! regulation of actin filament length GO:0030832 118 58 0,000 0,27812178 0,29136 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,27812178 0,29123511 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,27812178 0,29111033 ! gastrulation GO:0007369 122 58 0,000 0,27812178 0,29098566 ! regulation of tissue remodeling GO:0034103 146 58 0,000 0,27812178 0,29086109 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,27812178 0,29073664 ! nuclear export GO:0051168 110 59 0,000 0,28216996 0,29484227 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,28619556 0,2989208 ! regulation of endocytosis GO:0030100 104 60 0,000 0,28619556 0,29879305 ! adult behavior GO:0030534 104 60 0,000 0,28619556 0,29866542 ! positive regulation of secretion GO:0051047 110 61 0,000 0,29019869 0,30271366 ! regulation of cellular component size GO:0032535 125 61 0,000 0,29019869 0,30258446 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,29019869 0,30245537 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,29019869 0,3023264 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,29019869 0,30219753 ! proton transport GO:0015992 117 61 0,000 0,29019869 0,30206877 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,29417948 0,30608197 ! tRNA processing GO:0008033 102 62 0,000 0,29417948 0,30595167 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,29813806 0,30993671 ! mesoderm development GO:0007498 128 63 0,000 0,29813806 0,30980488 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,29813806 0,30967316 ! hydrogen transport GO:0006818 121 64 0,000 0,30207455 0,31362861 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,30207455 0,31349538 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,30598907 0,31742305 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,30598907 0,31728832 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,30598907 0,31715371 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,30598907 0,31701921 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,30598907 0,31688482 ! activation of MAPK activity GO:0000187 124 67 0,000 0,31375269 0,32478721 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,31375269 0,32464965 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,31375269 0,3245122 ! secondary metabolic process GO:0019748 125 67 0,000 0,31375269 0,32437487 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,31760204 0,32821564 ! hexose catabolic process GO:0019320 113 68 0,000 0,31760204 0,32807686 ! extracellular matrix organization GO:0030198 146 68 0,000 0,31760204 0,3279382 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,31760204 0,32779965 ! adaptive immune response GO:0002250 126 68 0,000 0,31760204 0,32766122 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,3214299 0,33147034 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,3214299 0,33133048 ! single fertilization GO:0007338 83 69 0,000 0,3214299 0,33119074 ! cell redox homeostasis GO:0045454 114 70 0,000 0,32523639 0,33497155 ! activation of immune response GO:0002253 120 70 0,000 0,32523639 0,33483039 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,32523639 0,33468935 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,32902164 0,33844205 ! carbohydrate transport GO:0008643 114 72 0,000 0,33278576 0,34216987 ! B cell activation GO:0042113 179 72 0,000 0,33278576 0,34202592 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,33278576 0,3418821 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,33278576 0,34173839 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,33278576 0,3415948 ! humoral immune response GO:0006959 115 73 0,000 0,33652888 0,34529191 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,33652888 0,34514695 ! regulation of immune effector process GO:0002697 156 73 0,000 0,33652888 0,34500212 ! acute inflammatory response GO:0002526 118 74 0,000 0,34025109 0,34867174 ! amino acid transport GO:0006865 148 74 0,000 0,34025109 0,34852554 ! transition metal ion transport GO:0000041 143 75 0,000 0,34395253 0,35216933 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,34395253 0,3520218 ! rhythmic process GO:0048511 142 75 0,000 0,34395253 0,35187439 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,34763331 0,35549107 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,34763331 0,35534233 ! regulation of blood pressure GO:0008217 134 76 0,000 0,34763331 0,35519371 ! amine catabolic process GO:0009310 136 77 0,000 0,35129354 0,35878349 ! neurotransmitter transport GO:0006836 142 77 0,000 0,35129354 0,35863356 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,35129354 0,35848375 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,35129354 0,35833407 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,35129354 0,35818452 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,35493333 0,36174473 ! antigen processing and presentation GO:0019882 117 78 0,000 0,35493333 0,36159388 ! fertilization GO:0009566 99 78 0,000 0,35493333 0,36144315 ! blood coagulation GO:0007596 151 79 0,000 0,3585528 0,36497687 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,3585528 0,36482486 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,3585528 0,36467298 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,3585528 0,36452122 ! protein oligomerization GO:0051259 149 79 0,000 0,3585528 0,36436959 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,36215207 0,36787422 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,36573124 0,37135554 ! protein import into nucleus GO:0006606 174 82 0,000 0,36929043 0,37481368 ! exocytosis GO:0006887 153 83 0,000 0,37282975 0,37824878 ! response to drug GO:0042493 149 83 0,000 0,37282975 0,37809177 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,37282975 0,37793488 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,37282975 0,37777813 ! nuclear import GO:0051170 177 83 0,000 0,37282975 0,3776215 ! response to metal ion GO:0010038 158 84 0,000 0,3763493 0,38102832 ! digestion GO:0007586 130 84 0,000 0,3763493 0,38087048 ! hemostasis GO:0007599 165 85 0,000 0,3798492 0,38425325 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,3798492 0,3840942 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,38679048 0,39095124 ! alcohol catabolic process GO:0046164 142 87 0,000 0,38679048 0,39078956 ! nucleosome assembly GO:0006334 126 87 0,000 0,38679048 0,39062801 ! amine biosynthetic process GO:0009309 146 88 0,000 0,39023208 0,39394089 ! sensory perception of smell GO:0007608 117 88 0,000 0,39023208 0,39377818 ! chromatin assembly GO:0031497 128 88 0,000 0,39023208 0,39361559 ! tube morphogenesis GO:0035239 194 89 0,000 0,39365445 0,39690377 ! cellular defense response GO:0006968 123 89 0,000 0,39365445 0,39674003 ! protein localization in nucleus GO:0034504 192 89 0,000 0,39365445 0,39657643 ! response to inorganic substance GO:0010035 173 90 0,000 0,39705772 0,39984007 ! defense response to bacterium GO:0042742 112 91 0,000 0,40044198 0,40308189 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,40380734 0,40630203 ! regulation of cell morphogenesis GO:0022604 243 93 0,000 0,4071539 0,40950061 ! amine transport GO:0015837 181 93 0,000 0,4071539 0,40933209 ! vitamin metabolic process GO:0006766 153 93 0,000 0,4071539 0,40916371 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,41048177 0,41233839 ! female pregnancy GO:0007565 166 94 0,000 0,41048177 0,41216891 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,41048177 0,41199958 ! nucleosome organization GO:0034728 143 95 0,000 0,41379106 0,41515053 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,41379106 0,41498011 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,41379106 0,41480983 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,41379106 0,41463968 ! negative regulation of multicellular organismal process GO:0051241 174 95 0,000 0,41379106 0,41446968 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,42035427 0,4208711 ! mRNA transport GO:0051028 185 100 0,000 0,43006226 0,43041463 ! positive regulation of immune response GO:0050778 175 100 0,000 0,43006226 0,43023837 ! hormone metabolic process GO:0042445 171 100 0,000 0,43006226 0,43006226