pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6439-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! androgen receptor signaling pathway GO:0030521 24 24 3,000 2,553E-06 4,704E-03 ! steroid hormone receptor signaling pathway GO:0030518 38 38 3,000 1,702E-05 0,01568727 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 3,000 2,095E-05 0,01287302 ! cell cycle arrest GO:0007050 49 49 3,000 4,732E-05 0,02180421 ! regulation of intracellular protein transport GO:0033157 25 25 2,000 1,455E-04 0,05364358 ! prostate gland development GO:0030850 5 5 1,000 1,702E-04 0,05228811 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 1,702E-04 0,04481838 ! T cell lineage commitment GO:0002360 5 5 1,000 1,702E-04 0,03921608 ! peptidyl-lysine modification GO:0018205 5 5 1,000 1,702E-04 0,03485874 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 1,702E-04 0,03137287 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 2,000 1,84E-04 0,03083407 ! positive regulation of cell cycle GO:0045787 29 29 2,000 2,286E-04 0,03510938 ! response to UV GO:0009411 29 29 2,000 2,286E-04 0,03240866 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 2,547E-04 0,03352587 GO:0018409|peptide or protein amino-terminal blocking, ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 2,547E-04 0,03129082 ! ER overload response GO:0006983 6 6 1,000 2,547E-04 0,02933514 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 2,547E-04 0,02760954 ! localization within membrane GO:0051668 6 6 1,000 2,547E-04 0,02607568 ! regulation of intracellular transport GO:0032386 31 31 2,000 2,796E-04 0,0271238 ! regulation of mRNA processing GO:0050684 7 7 1,000 3,556E-04 0,03276945 ! response to X-ray GO:0010165 7 7 1,000 3,556E-04 0,031209 ! regulation of intracellular pH GO:0051453 7 7 1,000 3,556E-04 0,02979041 ! response to gamma radiation GO:0010332 8 7 1,000 3,556E-04 0,02849517 ! regulation of protein catabolic process GO:0042176 35 34 2,000 3,691E-04 0,02834414 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 4,729E-04 0,0348627 ! catecholamine biosynthetic process GO:0042423 8 8 1,000 4,729E-04 0,03352183 ! release of cytochrome c from mitochondria GO:0001836 9 8 1,000 4,729E-04 0,03228028 ! meiosis GO:0007126 37 37 2,000 4,752E-04 0,03127919 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 38 38 2,000 5,145E-04 0,03269648 ! protein oligomerization GO:0051259 39 39 2,000 5,558E-04 0,03414365 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 6,064E-04 0,03605349 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 6,064E-04 0,03492682 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 6,064E-04 0,03386843 ! regulation of cellular pH GO:0030641 9 9 1,000 6,064E-04 0,0328723 ! histone acetylation GO:0016573 9 9 1,000 6,064E-04 0,03193309 ! regulation of caspase activity GO:0043281 41 41 2,000 6,446E-04 0,03300105 ! regulation of endopeptidase activity GO:0052548 42 42 2,000 6,922E-04 0,0344813 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 3,000 7,55E-04 0,03661517 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 7,561E-04 0,03572877 ! calcium-independent cell-cell adhesion GO:0016338 10 10 1,000 7,561E-04 0,03483555 ! apoptotic mitochondrial changes GO:0008637 11 10 1,000 7,561E-04 0,0339859 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 7,561E-04 0,03317672 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 7,561E-04 0,03240517 ! protein stabilization GO:0050821 10 10 1,000 7,561E-04 0,03166868 ! Wnt receptor signaling pathway GO:0016055 46 45 2,000 8,484E-04 0,03474763 ! regulation of peptidase activity GO:0052547 46 46 2,000 9,051E-04 0,03626103 ! phosphatidylinositol metabolic process GO:0046488 11 11 1,000 9,217E-04 0,0361409 ! protein amino acid acetylation GO:0006473 11 11 1,000 9,217E-04 0,03538796 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 9,217E-04 0,03466576 GO:0032388|positive regulation of intracellular transport, ! cellular response to starvation GO:0009267 11 11 1,000 9,217E-04 0,03397245 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 9,217E-04 0,03330632 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 9,217E-04 0,03266581 ! G1/S transition checkpoint GO:0031575 12 11 1,000 9,217E-04 0,03204948 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 9,217E-04 0,03145597 ! regulation of catabolic process GO:0009894 48 47 2,000 9,64E-04 0,03230363 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 1,103E-03 0,03630398 ! protein amino acid ADP-ribosylation GO:0006471 12 12 1,000 1,103E-03 0,03566707 ! regulation of chromosome organization GO:0033044 12 12 1,000 1,103E-03 0,03505212 ! somitogenesis GO:0001756 13 12 1,000 1,103E-03 0,03445802 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 1,103E-03 0,03388372 ! negative regulation of translation GO:0017148 12 12 1,000 1,103E-03 0,03332824 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 1,103E-03 0,03279069 ! response to light stimulus GO:0009416 53 52 2,000 1,295E-03 0,037897 ! phenol metabolic process GO:0018958 13 13 1,000 1,3E-03 0,03744358 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! mitochondrial membrane organization GO:0007006 13 13 1,000 1,3E-03 0,03686753 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 1,3E-03 0,03630893 ! negative regulation of DNA replication GO:0008156 13 13 1,000 1,3E-03 0,03576701 ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 1,3E-03 0,03524102 ! cell aging GO:0007569 13 13 1,000 1,3E-03 0,03473028 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 1,3E-03 0,03423413 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 1,3E-03 0,03375196 ! negative regulation of intracellular transport GO:0032387 13 13 1,000 1,3E-03 0,03328319 ! tissue homeostasis GO:0001894 13 13 1,000 1,3E-03 0,03282725 GO:0048871|multicellular organismal homeostasis, ! protein tetramerization GO:0051262 13 13 1,000 1,3E-03 0,03238364 ! regulation of protein transport GO:0051223 53 53 2,000 1,369E-03 0,03364818 GO:0070201|regulation of establishment of protein localization, ! protein amino acid acylation GO:0043543 14 14 1,000 1,513E-03 0,03669064 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 1,000 1,513E-03 0,03621414 ! base-excision repair GO:0006284 14 14 1,000 1,513E-03 0,03574986 ! regulation of protein localization GO:0032880 58 57 2,000 1,691E-03 0,03945109 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 1,741E-03 0,04011361 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 1,741E-03 0,03961838 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 1,741E-03 0,03913523 ! response to starvation GO:0042594 15 15 1,000 1,741E-03 0,03866372 ! response to ionizing radiation GO:0010212 16 15 1,000 1,741E-03 0,03820344 ! protein homooligomerization GO:0051260 15 15 1,000 1,741E-03 0,03775399 ! positive regulation of mitosis GO:0045840 16 16 1,000 1,985E-03 0,04253442 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 1,985E-03 0,04204552 ! segmentation GO:0035282 17 16 1,000 1,985E-03 0,04156773 ! cellular response to nutrient levels GO:0031669 16 16 1,000 1,985E-03 0,04110067 ! positive regulation of catabolic process GO:0009896 16 16 1,000 1,985E-03 0,040644 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 2,244E-03 0,04543815 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 2,244E-03 0,04494426 ! negative regulation of cell development GO:0010721 18 17 1,000 2,244E-03 0,04446099 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 2,244E-03 0,043988 ! meiosis I GO:0007127 18 18 1,000 2,517E-03 0,04883787 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 2,517E-03 0,04832914 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 2,517E-03 0,0478309 ! B cell differentiation GO:0030183 18 18 1,000 2,517E-03 0,04734283 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 2,517E-03 0,04686462 ! negative regulation of catabolic process GO:0009895 18 18 1,000 2,517E-03 0,04639598 ! negative regulation of protein metabolic process GO:0051248 66 66 2,000 2,578E-03 0,04704664 ! DNA damage checkpoint GO:0000077 19 19 1,000 2,806E-03 0,050705 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 2,806E-03 0,05021272 ! regulation of pH GO:0006885 19 19 1,000 2,806E-03 0,04972991 ! regulation of protein stability GO:0031647 19 19 1,000 2,806E-03 0,04925629 ! biogenic amine biosynthetic process GO:0042401 20 19 1,000 2,806E-03 0,04879161 ! response to radiation GO:0009314 70 68 2,000 2,808E-03 0,04836183 ! regulation of cell size GO:0008361 68 68 2,000 2,808E-03 0,04791404 ! regulation of mitotic cell cycle GO:0007346 72 69 2,000 2,927E-03 0,04949238 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 3,11E-03 0,05210531 ! regulation of cell migration GO:0030334 71 71 2,000 3,175E-03 0,05271829 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 3,304E-03 0,05436547 ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 3,428E-03 0,05591502 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 3,428E-03 0,05542453 ! DNA integrity checkpoint GO:0031570 21 21 1,000 3,428E-03 0,05494258 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 3,428E-03 0,05446894 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 3,428E-03 0,05400339 ! negative regulation of protein transport GO:0051224 21 21 1,000 3,428E-03 0,05354574 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 3,761E-03 0,05825314 GO:0090047|positive regulation of transcription regulator activity, ! sister chromatid segregation GO:0000819 22 22 1,000 3,761E-03 0,0577677 ! odontogenesis GO:0042476 22 22 1,000 3,761E-03 0,05729028 ! spindle organization GO:0007051 22 22 1,000 3,761E-03 0,05682069 ! neuron migration GO:0001764 22 22 1,000 3,761E-03 0,05635873 ! aerobic respiration GO:0009060 22 22 1,000 3,761E-03 0,05590423 ! cytokinesis GO:0000910 23 22 1,000 3,761E-03 0,05545699 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 4,109E-03 0,06009957 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 4,109E-03 0,05962634 ! calcium-mediated signaling GO:0019722 23 23 1,000 4,109E-03 0,05916051 ! cell projection assembly GO:0030031 25 23 1,000 4,109E-03 0,0587019 ! regulation of locomotion GO:0040012 79 79 2,000 4,295E-03 0,06088904 ! regulation of cell motion GO:0051270 79 79 2,000 4,295E-03 0,06042424 ! mitochondrial transport GO:0006839 24 24 1,000 4,471E-03 0,06242 ! T cell differentiation GO:0030217 24 24 1,000 4,471E-03 0,06195068 ! regulation of gene-specific transcription GO:0032583 25 25 1,000 4,847E-03 0,06666112 ! positive regulation of DNA binding GO:0043388 26 25 1,000 4,847E-03 0,06616733 ! positive regulation of binding GO:0051099 27 26 1,000 5,237E-03 0,07096895 ! negative regulation of cell migration GO:0030336 26 26 1,000 5,237E-03 0,07045093 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 5,237E-03 0,06994041 ! double-strand break repair GO:0006302 27 26 1,000 5,237E-03 0,06943724 ! regulation of cellular localization GO:0060341 86 85 2,000 5,274E-03 0,06943307 ! heart development GO:0007507 90 87 2,000 5,628E-03 0,07356748 ! activation of caspase activity GO:0006919 27 27 1,000 5,641E-03 0,0732168 ! mesenchymal cell development GO:0014031 29 27 1,000 5,641E-03 0,07270479 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! cell growth GO:0016049 27 27 1,000 5,641E-03 0,0721999 ! histone modification GO:0016570 28 28 1,000 6,059E-03 0,07701655 ! protein amino acid autophosphorylation GO:0046777 28 28 1,000 6,059E-03 0,07648904 ! negative regulation of cell cycle GO:0045786 92 91 2,000 6,379E-03 0,07996994 ! phosphoinositide metabolic process GO:0030384 29 29 1,000 6,491E-03 0,08083382 ! regulation of epithelial cell proliferation GO:0050678 29 29 1,000 6,491E-03 0,08029131 ! covalent chromatin modification GO:0016569 29 29 1,000 6,491E-03 0,07975604 ! positive regulation of protein transport GO:0051222 29 29 1,000 6,491E-03 0,07922785 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 6,937E-03 0,08410916 GO:0043280|positive regulation of caspase activity, ! activation of phospholipase C activity GO:0007202 30 30 1,000 6,937E-03 0,08355942 GO:0010863|positive regulation of phospholipase C activity, ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 1,000 6,937E-03 0,08301683 ! establishment of organelle localization GO:0051656 31 30 1,000 6,937E-03 0,08248124 ! pattern specification process GO:0007389 96 94 2,000 6,979E-03 0,08244642 ! B cell activation GO:0042113 31 31 1,000 7,396E-03 0,08682004 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 7,396E-03 0,08627055 ! aging GO:0007568 32 31 1,000 7,396E-03 0,08572796 ! regulation of DNA replication GO:0006275 32 31 1,000 7,396E-03 0,08519216 ! negative regulation of cell motion GO:0051271 31 31 1,000 7,396E-03 0,08466302 ! regulation of cell growth GO:0001558 97 96 2,000 7,397E-03 0,0841507 ! posttranscriptional regulation of gene expression GO:0010608 98 98 2,000 7,83E-03 0,08852872 ! negative regulation of cell growth GO:0030308 32 32 1,000 7,869E-03 0,08842475 ! regulation of phospholipase activity GO:0010517 32 32 1,000 7,869E-03 0,08788884 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 7,869E-03 0,08735939 ! positive regulation of lipase activity GO:0060193 32 32 1,000 7,869E-03 0,08683628 ! negative regulation of cell size GO:0045792 33 33 1,000 8,354E-03 0,09164953 ! regulation of neuron apoptosis GO:0043523 34 33 1,000 8,354E-03 0,09110723 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 1,000 9,366E-03 0,10153449 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 9,366E-03 0,10094073 ! regulation of mitosis GO:0007088 37 36 1,000 9,891E-03 0,10598101 GO:0051783|regulation of nuclear division, ! positive regulation of cell migration GO:0030335 36 36 1,000 9,891E-03 0,1053684 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 9,891E-03 0,10476283 GO:0045937|positive regulation of phosphate metabolic process, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 1,000 9,891E-03 0,10416419 ! positive regulation of organelle organization GO:0010638 36 36 1,000 9,891E-03 0,10357235 ! regulation of lipase activity GO:0060191 36 36 1,000 9,891E-03 0,10298719 ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,01042883 0,10797937 GO:0090046|regulation of transcription regulator activity, ! response to drug GO:0042493 37 37 1,000 0,01042883 0,10737614 ! lung development GO:0030324 38 37 1,000 0,01042883 0,1067796 ! negative regulation of growth GO:0045926 37 37 1,000 0,01042883 0,10618966 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,01042883 0,1056062 ! ATP synthesis coupled electron transport GO:0042773 37 37 1,000 0,01042883 0,10502912 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 0,01042883 0,10445831 ! RNA elongation GO:0006354 38 38 1,000 0,01097962 0,10938079 ! chromosome segregation GO:0007059 38 38 1,000 0,01097962 0,10879272 ! urogenital system development GO:0001655 38 38 1,000 0,01097962 0,10821095 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,01154307 0,11315897 ! respiratory system development GO:0060541 40 39 1,000 0,01154307 0,11256025 ! lymphocyte differentiation GO:0030098 39 39 1,000 0,01154307 0,11196782 ! positive regulation of cell motion GO:0051272 39 39 1,000 0,01154307 0,11138161 ! respiratory tube development GO:0030323 40 39 1,000 0,01154307 0,11080149 ! organelle localization GO:0051640 41 40 1,000 0,01211907 0,11572771 ! cell cycle checkpoint GO:0000075 42 41 1,000 0,0127075 0,12072129 ! respiratory electron transport chain GO:0022904 43 42 1,000 0,01330827 0,12578019 ! protein ubiquitination GO:0016567 43 42 1,000 0,01330827 0,12513845 ! negative regulation of ligase activity GO:0051352 43 42 1,000 0,01330827 0,12450323 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! forebrain development GO:0030900 43 42 1,000 0,01330827 0,12387442 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,01330827 0,12325194 ! reproductive structure development GO:0048608 43 43 1,000 0,01392125 0,12828434 ! mitochondrion organization GO:0007005 44 43 1,000 0,01392125 0,12764611 ! protein import into nucleus GO:0006606 44 44 1,000 0,01454635 0,13271749 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,01454635 0,13206371 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 0,01454635 0,13141633 ! amine biosynthetic process GO:0009309 46 45 1,000 0,01518347 0,13650308 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,01518347 0,13584044 ! regulation of DNA binding GO:0051101 47 45 1,000 0,01518347 0,13518421 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 0,01518347 0,13453429 ! nuclear import GO:0051170 45 45 1,000 0,01518347 0,13389058 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 0,01583249 0,13894892 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 1,000 0,01583249 0,1382904 ! positive regulation of ligase activity GO:0051351 47 46 1,000 0,01583249 0,13763808 ! sex differentiation GO:0007548 47 47 1,000 0,01649331 0,1427097 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 0,01716583 0,14783466 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,01716583 0,14714706 ! glycerophospholipid metabolic process GO:0006650 49 48 1,000 0,01716583 0,14646582 ! protein localization in nucleus GO:0034504 48 48 1,000 0,01716583 0,14579086 ! leukocyte differentiation GO:0002521 50 49 1,000 0,01784994 0,15090567 ! ossification GO:0001503 50 49 1,000 0,01784994 0,15021661 GO:0060348|bone development, ! gland development GO:0048732 51 49 1,000 0,01784994 0,1495338 ! skeletal muscle tissue development GO:0007519 50 49 1,000 0,01784994 0,14885718 GO:0060538|skeletal muscle organ development, ! positive regulation of MAP kinase activity GO:0043406 50 49 1,000 0,01784994 0,14818665 ! regulation of ligase activity GO:0051340 50 49 1,000 0,01784994 0,14752214 ! regulation of DNA metabolic process GO:0051052 51 50 1,000 0,01854554 0,15258677 ! negative regulation of transport GO:0051051 51 50 1,000 0,01854554 0,15190861 ! T cell activation GO:0042110 51 50 1,000 0,01854554 0,15123644 ! regulation of neurogenesis GO:0050767 51 50 1,000 0,01854554 0,1505702 ! transcription initiation GO:0006352 50 50 1,000 0,01854554 0,14990981 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,01854554 0,14925518 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,01854554 0,14860625 ! biogenic amine metabolic process GO:0006576 52 51 1,000 0,01925254 0,15360358 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,01925254 0,1529415 ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 0,01925254 0,1522851 GO:0051325|interphase, ! cell fate commitment GO:0045165 52 52 1,000 0,01997082 0,15729156 ! response to hypoxia GO:0001666 53 53 1,000 0,02070029 0,16234315 ! rRNA transcription GO:0009303 5 5 0,000 0,02090468 0,1632514 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,02090468 0,16256258 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,02090468 0,16187954 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,02090468 0,16120222 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,02090468 0,16053055 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,02090468 0,15986445 ! reproductive cellular process GO:0048610 5 5 0,000 0,02090468 0,15920385 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,02090468 0,15854869 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,02090468 0,1578989 ! metencephalon development GO:0022037 5 5 0,000 0,02090468 0,15725441 ! water transport GO:0006833 5 5 0,000 0,02090468 0,15661517 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,02090468 0,1559811 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,02090468 0,15535214 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,02090468 0,15472824 ! glycerol metabolic process GO:0006071 5 5 0,000 0,02090468 0,15410933 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,02090468 0,15349534 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,02090468 0,15288624 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,02090468 0,15228194 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,02090468 0,15168241 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,02090468 0,15108757 ! filopodium assembly GO:0046847 7 5 0,000 0,02090468 0,15049739 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,02090468 0,14991179 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,02090468 0,14933074 ! GTP metabolic process GO:0046039 5 5 0,000 0,02090468 0,14875417 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,02090468 0,14818204 ! mRNA stabilization GO:0048255 5 5 0,000 0,02090468 0,1476143 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,02090468 0,14705088 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,02090468 0,14649175 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,02090468 0,14593686 ! social behavior GO:0035176 5 5 0,000 0,02090468 0,14538616 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,02090468 0,14483959 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,02090468 0,14429712 ! memory GO:0007613 5 5 0,000 0,02090468 0,1437587 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,02090468 0,14322428 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,02090468 0,14269382 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,02090468 0,14216727 ! response to lipid GO:0033993 5 5 0,000 0,02090468 0,1416446 ! erythrocyte maturation GO:0043249 5 5 0,000 0,02090468 0,14112576 ! hippocampus development GO:0021766 6 5 0,000 0,02090468 0,1406107 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,02090468 0,14009939 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,02090468 0,13959178 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,02090468 0,13908784 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,02090468 0,13858752 ! mechanosensory behavior GO:0007638 5 5 0,000 0,02090468 0,13809079 ! heart looping GO:0001947 5 5 0,000 0,02090468 0,13759761 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,02090468 0,13710794 ! response to interferon-gamma GO:0034341 5 5 0,000 0,02090468 0,13662174 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,02090468 0,13613898 ! endocrine pancreas development GO:0031018 5 5 0,000 0,02090468 0,13565962 ! pH reduction GO:0045851 5 5 0,000 0,02090468 0,13518362 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,02090468 0,13471095 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,02090468 0,13424157 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,02090468 0,13377546 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,02090468 0,13331256 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,02090468 0,13285287 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,02090468 0,13239633 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,02090468 0,13194292 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,02090468 0,1314926 ! adrenal gland development GO:0030325 5 5 0,000 0,02090468 0,13104534 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,02090468 0,13060112 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,02090468 0,1301599 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,02090468 0,12972165 ! astrocyte differentiation GO:0048708 5 5 0,000 0,02090468 0,12928635 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,02090468 0,12885395 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,02090468 0,12842444 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,02090468 0,12799778 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,02090468 0,12757394 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,02090468 0,12715291 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,02090468 0,12673464 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,02090468 0,12631912 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,02090468 0,12590631 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,02090468 0,12549619 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,02090468 0,12508874 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,02090468 0,12468392 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,02090468 0,12428171 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,02090468 0,12388209 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,02090468 0,12348504 ! response to ATP GO:0033198 5 5 0,000 0,02090468 0,12309052 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,02090468 0,12269851 ! regulation of appetite GO:0032098 5 5 0,000 0,02090468 0,12230899 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,02090468 0,12192193 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,02090468 0,12153732 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,02090468 0,12115513 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,02090468 0,12077533 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02090468 0,12039791 ! receptor clustering GO:0043113 5 5 0,000 0,02090468 0,12002284 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,02090468 0,1196501 ! fear response GO:0042596 5 5 0,000 0,02090468 0,11927966 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,02090468 0,11891152 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,02090468 0,11854563 ! retinol metabolic process GO:0042572 5 5 0,000 0,02090468 0,118182 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,02090468 0,11782058 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,02090468 0,11746138 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,02090468 0,11710435 ! parturition GO:0007567 5 5 0,000 0,02090468 0,11674949 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02090468 0,11639677 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,02090468 0,11604618 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,02090468 0,11569769 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,02090468 0,11535129 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,02090468 0,11500696 ! protein heterooligomerization GO:0051291 5 5 0,000 0,02090468 0,11466468 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,02090468 0,11432443 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,02090468 0,11398619 ! response to UV-B GO:0010224 5 5 0,000 0,02090468 0,11364994 ! oligodendrocyte development GO:0014003 5 5 0,000 0,02090468 0,11331568 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,02090468 0,11298338 ! activated T cell proliferation GO:0050798 5 5 0,000 0,02090468 0,11265302 ! interaction with symbiont GO:0051702 5 5 0,000 0,02090468 0,11232458 ! cellular extravasation GO:0045123 5 5 0,000 0,02090468 0,11199806 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,02090468 0,11167342 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,02090468 0,11135067 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,02090468 0,11102977 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,02090468 0,11071072 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,02090468 0,1103935 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,02090468 0,11007809 ! response to amine stimulus GO:0014075 5 5 0,000 0,02090468 0,10976448 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,02090468 0,10945265 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,02090468 0,10914258 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,02090468 0,10883427 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,02090468 0,10852769 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,02090468 0,10822284 ! neuron recognition GO:0008038 5 5 0,000 0,02090468 0,1079197 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,02090468 0,10761824 ! decidualization GO:0046697 5 5 0,000 0,02090468 0,10731847 ! hair follicle maturation GO:0048820 5 5 0,000 0,02090468 0,10702036 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,02090468 0,10672391 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,02090468 0,10642909 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,02090468 0,1061359 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,02090468 0,10584432 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,02090468 0,10555433 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,02090468 0,10526593 ! postreplication repair GO:0006301 5 5 0,000 0,02090468 0,1049791 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,02090468 0,10469383 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,02090468 0,10441011 ! histone methylation GO:0016571 5 5 0,000 0,02090468 0,10412792 ! DNA methylation GO:0006306 5 5 0,000 0,02090468 0,10384725 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02090468 0,10356809 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,02090468 0,10329043 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,02090468 0,10301425 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,02090468 0,10273955 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,02090468 0,10246631 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,02090468 0,10219451 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,02090468 0,10192416 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,02090468 0,10165523 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,02090468 0,10138771 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,02090468 0,1011216 ! sterol catabolic process GO:0016127 5 5 0,000 0,02090468 0,10085689 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,02090468 0,10059355 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,02090468 0,10033159 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,02090468 0,10007099 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,02090468 0,09981174 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,02090468 0,09955383 ! zymogen activation GO:0031638 5 5 0,000 0,02090468 0,09929725 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,02090468 0,09904198 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,02090468 0,09878803 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,02090468 0,09853537 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,02090468 0,09828401 ! nucleosome positioning GO:0016584 5 5 0,000 0,02090468 0,09803392 ! regulation of isotype switching GO:0045191 5 5 0,000 0,02090468 0,0977851 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,02090468 0,09753755 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,02090468 0,09729124 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,02090468 0,09704617 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,02090468 0,09680234 ! NADPH regeneration GO:0006740 5 5 0,000 0,02090468 0,09655973 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,02090468 0,09631833 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,02090468 0,09607813 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,02090468 0,09583913 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,02090468 0,09560132 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,02090468 0,09536468 ! sarcomere organization GO:0045214 5 5 0,000 0,02090468 0,09512921 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,02090468 0,0948949 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,02090468 0,09466175 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,02090468 0,09442973 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,02090468 0,09419885 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,02090468 0,0939691 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,02090468 0,09374047 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,02090468 0,09351294 ! spleen development GO:0048536 5 5 0,000 0,02090468 0,09328652 ! male genitalia development GO:0030539 5 5 0,000 0,02090468 0,09306119 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,02090468 0,09283694 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,02090468 0,09261378 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,02090468 0,09239168 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,02090468 0,09217065 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,02090468 0,09195067 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,02090468 0,09173174 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,02090468 0,09151385 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,02090468 0,09129699 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,02090468 0,09108116 ! ATP catabolic process GO:0006200 5 5 0,000 0,02090468 0,09086635 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02090468 0,09065254 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,02090468 0,09043974 ! blastocyst formation GO:0001825 5 5 0,000 0,02090468 0,09022794 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,02090468 0,09001713 ! embryonic gut development GO:0048566 5 5 0,000 0,02090468 0,0898073 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,02090468 0,08959844 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,02090468 0,08939056 ! activation of innate immune response GO:0002218 5 5 0,000 0,02090468 0,08918364 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,02090468 0,08897767 ! catecholamine transport GO:0051937 5 5 0,000 0,02090468 0,08877265 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,02090468 0,08856858 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,02090468 0,08836544 ! muscle adaptation GO:0043500 5 5 0,000 0,02090468 0,08816323 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,02090468 0,08796194 ! embryonic heart tube development GO:0035050 5 5 0,000 0,02090468 0,08776157 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,02090468 0,08756212 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,02090468 0,08736356 ! defense response to fungus GO:0050832 5 5 0,000 0,02090468 0,08716591 ! lysogeny GO:0030069 5 5 0,000 0,02090468 0,08696915 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,02090468 0,08677327 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,02090468 0,08657827 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,02090468 0,08638415 ! response to nicotine GO:0035094 5 5 0,000 0,02090468 0,0861909 ! establishment of cell polarity GO:0030010 5 5 0,000 0,02090468 0,08599851 ! mitochondrion localization GO:0051646 5 5 0,000 0,02090468 0,08580697 ! nucleus localization GO:0051647 5 5 0,000 0,02090468 0,08561629 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,02090468 0,08542646 ! response to oxygen levels GO:0070482 55 54 1,000 0,02144085 0,08742365 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,0221924 0,09028829 ! in utero embryonic development GO:0001701 55 55 1,000 0,0221924 0,09008941 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,0221924 0,08989142 ! reproductive developmental process GO:0003006 56 56 1,000 0,02295484 0,0927758 ! regulation of nervous system development GO:0051960 57 56 1,000 0,02295484 0,09257279 ! regulation of binding GO:0051098 60 57 1,000 0,02372807 0,09548215 ! ATP metabolic process GO:0046034 57 57 1,000 0,02372807 0,09527413 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,02503469 0,10030201 ! axon extension GO:0048675 7 6 0,000 0,02503469 0,10008444 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,02503469 0,0998678 ! tRNA modification GO:0006400 6 6 0,000 0,02503469 0,09965211 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,02503469 0,09943734 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,02503469 0,09922349 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,02503469 0,09901057 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,02503469 0,09879855 ! virus-host interaction GO:0019048 6 6 0,000 0,02503469 0,09858745 ! regulation of S phase GO:0033261 6 6 0,000 0,02503469 0,09837724 ! myotube differentiation GO:0014902 6 6 0,000 0,02503469 0,09816793 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,02503469 0,0979595 ! bone remodeling GO:0046849 6 6 0,000 0,02503469 0,09775196 ! N-glycan processing GO:0006491 6 6 0,000 0,02503469 0,0975453 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,02503469 0,0973395 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,02503469 0,09713458 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,02503469 0,09693051 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,02503469 0,09672731 ! RNA methylation GO:0001510 6 6 0,000 0,02503469 0,09652495 ! cartilage condensation GO:0001502 7 6 0,000 0,02503469 0,09632343 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,02503469 0,09612276 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,02503469 0,09592292 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,02503469 0,09572391 ! artery development GO:0060840 6 6 0,000 0,02503469 0,09552572 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,02503469 0,09532836 ! bile acid metabolic process GO:0008206 6 6 0,000 0,02503469 0,0951318 ! androgen metabolic process GO:0008209 6 6 0,000 0,02503469 0,09493606 ! estrogen metabolic process GO:0008210 6 6 0,000 0,02503469 0,09474112 ! limbic system development GO:0021761 7 6 0,000 0,02503469 0,09454698 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,02503469 0,09435363 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,02503469 0,09416107 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,02503469 0,0939693 ! pathogenesis GO:0009405 6 6 0,000 0,02503469 0,0937783 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,02503469 0,09358808 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,02503469 0,09339863 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,02503469 0,09320995 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,02503469 0,09302203 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,02503469 0,09283486 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,02503469 0,09264844 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,02503469 0,09246278 ! arginine metabolic process GO:0006525 6 6 0,000 0,02503469 0,09227785 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,02503469 0,09209366 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,02503469 0,09191021 ! glutamate catabolic process GO:0006538 7 6 0,000 0,02503469 0,09172749 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,02503469 0,09154549 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,02503469 0,09136421 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,02503469 0,09118365 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,02503469 0,0910038 ! V(D)J recombination GO:0033151 6 6 0,000 0,02503469 0,09082466 ! focal adhesion formation GO:0048041 7 6 0,000 0,02503469 0,09064622 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,02503469 0,09046848 ! negative regulation of T cell proliferation GO:0042130 6 6 0,000 0,02503469 0,09029144 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,02503469 0,09011509 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,02503469 0,08993943 ! regulation of heart rate GO:0002027 6 6 0,000 0,02503469 0,08976445 ! lipid digestion GO:0044241 6 6 0,000 0,02503469 0,08959015 ! asymmetric protein localization GO:0008105 6 6 0,000 0,02503469 0,08941652 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,02503469 0,08924357 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,02503469 0,08907128 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,02503469 0,08889966 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,02503469 0,0887287 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,02503469 0,0885584 ! ruffle organization GO:0031529 6 6 0,000 0,02503469 0,08838875 ! peptidyl-serine phosphorylation GO:0018105 6 6 0,000 0,02503469 0,08821974 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,02503469 0,08805138 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,02503469 0,08788367 ! neutral amino acid transport GO:0015804 6 6 0,000 0,02503469 0,08771659 ! L-amino acid transport GO:0015807 6 6 0,000 0,02503469 0,08755014 ! bone mineralization GO:0030282 6 6 0,000 0,02503469 0,08738433 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,02503469 0,08721914 ! negative regulation of ossification GO:0030279 6 6 0,000 0,02503469 0,08705458 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,02503469 0,08689063 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,02503469 0,0867273 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,02503469 0,08656459 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,02503469 0,08640248 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,02503469 0,08624098 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,02503469 0,08608008 ! regulation of organ growth GO:0046620 6 6 0,000 0,02503469 0,08591979 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,02503469 0,08576008 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,02503469 0,08560097 ! response to dsRNA GO:0043331 6 6 0,000 0,02503469 0,08544245 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,02503469 0,08528452 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,02503469 0,08512717 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 0,000 0,02503469 0,0849704 ! genitalia development GO:0048806 6 6 0,000 0,02503469 0,0848142 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,02503469 0,08465858 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,02503469 0,08450353 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 0,000 0,02503469 0,08434904 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,02503469 0,08419512 ! multicellular organismal aging GO:0010259 6 6 0,000 0,02503469 0,08404176 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,02503469 0,08388895 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,02503469 0,08373671 ! erythrocyte development GO:0048821 6 6 0,000 0,02503469 0,08358501 ! renal water homeostasis GO:0003091 6 6 0,000 0,02503469 0,08343386 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,02503469 0,08328326 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,02503469 0,0831332 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,02503469 0,08298368 ! ribosome assembly GO:0042255 6 6 0,000 0,02503469 0,08283469 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,02503469 0,08268625 ! diencephalon development GO:0021536 6 6 0,000 0,02503469 0,08253833 ! fucose catabolic process GO:0019317 6 6 0,000 0,02503469 0,08239094 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,02503469 0,08224407 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,02503469 0,08209773 ! regulation of lipid transport GO:0032368 6 6 0,000 0,02503469 0,08195191 ! regulation of cell division GO:0051302 6 6 0,000 0,02503469 0,0818066 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,02503469 0,08166181 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,02503469 0,08151754 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,02503469 0,08137377 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,02503469 0,0812305 ! neuroblast proliferation GO:0007405 6 6 0,000 0,02503469 0,08108774 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,02503469 0,08094548 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,02503469 0,08080372 ! regulation of glucose transport GO:0010827 6 6 0,000 0,02503469 0,08066246 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,02503469 0,08052168 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,02503469 0,0803814 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,02503469 0,08024161 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,02503469 0,0801023 ! thymus development GO:0048538 6 6 0,000 0,02503469 0,07996347 ! lymph node development GO:0048535 6 6 0,000 0,02503469 0,07982513 ! organic cation transport GO:0015695 6 6 0,000 0,02503469 0,07968726 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,02503469 0,07954987 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,02503469 0,07941295 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,02503469 0,0792765 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,02503469 0,07914052 ! sperm-egg recognition GO:0035036 7 6 0,000 0,02503469 0,07900501 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,02503469 0,07886996 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,02503469 0,07873537 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,02503469 0,07860124 ! alditol metabolic process GO:0019400 6 6 0,000 0,02503469 0,07846756 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,02503469 0,07833434 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,02503469 0,07820157 ! maternal placenta development GO:0001893 6 6 0,000 0,02503469 0,07806925 ! regulation of embryonic development GO:0045995 6 6 0,000 0,02503469 0,07793737 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,02503469 0,07780594 ! peptidyl-amino acid modification GO:0018193 61 59 1,000 0,0253065 0,07851833 ! regulation of cell development GO:0060284 60 59 1,000 0,0253065 0,07838636 ! cellular aromatic compound metabolic process GO:0006725 60 59 1,000 0,0253065 0,07825484 ! protein localization in organelle GO:0033365 59 59 1,000 0,0253065 0,07812376 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,02611152 0,08047413 ! cellular respiration GO:0045333 62 61 1,000 0,02692694 0,08284867 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,02692694 0,08271059 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,02692694 0,08257296 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 1,000 0,02775267 0,08496373 ! protein import GO:0017038 62 62 1,000 0,02775267 0,08482283 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,02858861 0,08723312 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 1,000 0,02858861 0,08708894 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 1,000 0,02858861 0,08694522 ! respiratory burst GO:0045730 7 7 0,000 0,02914786 0,08850002 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,02914786 0,08835446 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,02914786 0,08820938 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,02914786 0,08806478 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,02914786 0,08792065 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,02914786 0,08777698 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,02914786 0,08763379 ! regulation of chemokine production GO:0032642 7 7 0,000 0,02914786 0,08749107 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,02914786 0,0873488 GO:0000725|recombinational repair, ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,02914786 0,087207 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,02914786 0,08706566 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,02914786 0,08692478 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,02914786 0,08678435 ! gene silencing by RNA GO:0031047 7 7 0,000 0,02914786 0,08664438 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,02914786 0,08650485 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,02914786 0,08636578 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,02914786 0,08622715 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,02914786 0,08608897 ! axis specification GO:0009798 7 7 0,000 0,02914786 0,08595122 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,02914786 0,08581392 ! visual behavior GO:0007632 7 7 0,000 0,02914786 0,08567706 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,02914786 0,08554063 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,02914786 0,08540463 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,02914786 0,08526907 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,02914786 0,08513394 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,02914786 0,08499923 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,02914786 0,08486495 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,02914786 0,0847311 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,02914786 0,08459766 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,02914786 0,08446465 ! digestive system development GO:0055123 7 7 0,000 0,02914786 0,08433205 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,02914786 0,08419987 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,02914786 0,0840681 ! protein targeting to ER GO:0045047 8 7 0,000 0,02914786 0,08393674 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,02914786 0,08380579 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,02914786 0,08367526 ! endoderm development GO:0007492 7 7 0,000 0,02914786 0,08354512 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,02914786 0,0834154 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,02914786 0,08328607 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,02914786 0,08315714 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,02914786 0,08302862 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,02914786 0,08290049 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,02914786 0,08277275 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 0,000 0,02914786 0,08264541 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,02914786 0,08251846 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,02914786 0,08239189 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,02914786 0,08226572 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,02914786 0,08213993 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,02914786 0,08201453 ! UV protection GO:0009650 7 7 0,000 0,02914786 0,0818895 ! DNA integration GO:0015074 7 7 0,000 0,02914786 0,08176486 ! myofibril assembly GO:0030239 7 7 0,000 0,02914786 0,0816406 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,02914786 0,08151671 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,02914786 0,0813932 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,02914786 0,08127007 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,02914786 0,0811473 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,02914786 0,08102491 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,02914786 0,08090288 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,02914786 0,08078122 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,02914786 0,08065993 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,02914786 0,080539 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,02914786 0,08041843 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,02914786 0,08029823 ! axon cargo transport GO:0008088 7 7 0,000 0,02914786 0,08017838 ! eating behavior GO:0042755 7 7 0,000 0,02914786 0,08005889 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,02914786 0,07993975 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,02914786 0,07982097 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,02914786 0,07970254 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,02914786 0,07958447 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,02914786 0,07946674 ! cranial nerve development GO:0021545 7 7 0,000 0,02914786 0,07934936 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,02914786 0,07923232 ! induction of an organ GO:0001759 7 7 0,000 0,02914786 0,07911563 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,02914786 0,07899929 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,02914786 0,07888328 ! autonomic nervous system development GO:0048483 7 7 0,000 0,02914786 0,07876762 ! intracellular lipid transport GO:0032365 7 7 0,000 0,02914786 0,07865229 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,02914786 0,0785373 ! platelet activation GO:0030168 8 7 0,000 0,02914786 0,07842265 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,02914786 0,07830833 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,02914786 0,07819434 ! natural killer cell activation GO:0030101 7 7 0,000 0,02914786 0,07808069 ! NADP metabolic process GO:0006739 7 7 0,000 0,02914786 0,07796736 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,02914786 0,07785437 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,02914786 0,0777417 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,02914786 0,07762936 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,02914786 0,07751734 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,02914786 0,07740564 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,02914786 0,07729427 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,02914786 0,07718321 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,02914786 0,07707247 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,02914786 0,07696206 ! cell-cell recognition GO:0009988 8 7 0,000 0,02914786 0,07685195 ! hormone catabolic process GO:0042447 7 7 0,000 0,02914786 0,07674216 ! dopamine metabolic process GO:0042417 7 7 0,000 0,02914786 0,07663269 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,02914786 0,07652352 ! oxygen transport GO:0015671 7 7 0,000 0,02914786 0,07641467 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,02914786 0,07630613 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,02914786 0,07619789 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,02914786 0,07608996 ! regulation of axon extension GO:0030516 7 7 0,000 0,02914786 0,07598234 ! cell killing GO:0001906 7 7 0,000 0,02914786 0,07587502 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,02914786 0,075768 ! adult feeding behavior GO:0008343 7 7 0,000 0,02914786 0,07566129 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,02914786 0,07555487 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,02914786 0,07544876 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,02914786 0,07534294 ! negative regulation of T cell activation GO:0050868 7 7 0,000 0,02914786 0,07523742 ! response to cold GO:0009409 7 7 0,000 0,02914786 0,07513219 ! glycerolipid metabolic process GO:0046486 65 64 1,000 0,02943467 0,07576549 ! angiogenesis GO:0001525 65 64 1,000 0,02943467 0,07565982 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,02943467 0,07555445 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,03029075 0,07764375 ! nucleoside triphosphate metabolic process GO:0009141 66 66 1,000 0,03115677 0,07975267 ! regulation of MAP kinase activity GO:0043405 67 66 1,000 0,03115677 0,07964206 ! striated muscle tissue development GO:0014706 69 67 1,000 0,03203262 0,08176748 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,03203262 0,08165439 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,03324429 0,084626 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,03324429 0,08450927 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,03324429 0,08439287 ! positive regulation of translation GO:0045727 8 8 0,000 0,03324429 0,08427678 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,03324429 0,08416102 ! superoxide anion generation GO:0042554 8 8 0,000 0,03324429 0,08404557 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,03324429 0,08393044 ! cGMP metabolic process GO:0046068 8 8 0,000 0,03324429 0,08381562 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,03324429 0,08370112 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,03324429 0,08358693 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,03324429 0,08347305 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,03324429 0,08335948 ! negative regulation of bone remodeling GO:0046851 8 8 0,000 0,03324429 0,08324622 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,03324429 0,08313327 ! zinc ion transport GO:0006829 8 8 0,000 0,03324429 0,08302062 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,03324429 0,08290828 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,03324429 0,08279624 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,03324429 0,08268451 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,03324429 0,08257307 ! lipid localization GO:0010876 8 8 0,000 0,03324429 0,08246194 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,03324429 0,0823511 ! response to cAMP GO:0051591 8 8 0,000 0,03324429 0,08224057 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,03324429 0,08213032 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,03324429 0,08202038 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,03324429 0,08191072 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,03324429 0,08180136 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,03324429 0,08169229 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,03324429 0,08158352 ! sensory perception of taste GO:0050909 8 8 0,000 0,03324429 0,08147503 ! organelle fusion GO:0048284 8 8 0,000 0,03324429 0,08136683 ! pancreas development GO:0031016 8 8 0,000 0,03324429 0,08125891 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,03324429 0,08115129 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,03324429 0,08104394 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,03324429 0,08093688 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,03324429 0,08083011 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,03324429 0,08072361 ! sperm motility GO:0030317 8 8 0,000 0,03324429 0,0806174 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,03324429 0,08051146 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,03324429 0,0804058 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,03324429 0,08030042 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,03324429 0,08019532 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,03324429 0,08009049 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,03324429 0,07998593 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,03324429 0,07988164 ! Golgi organization GO:0007030 8 8 0,000 0,03324429 0,07977763 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,03324429 0,07967389 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,03324429 0,07957042 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,03324429 0,07946721 ! fructose metabolic process GO:0006000 8 8 0,000 0,03324429 0,07936428 ! mannose metabolic process GO:0006013 9 8 0,000 0,03324429 0,07926161 ! NAD metabolic process GO:0019674 8 8 0,000 0,03324429 0,0791592 ! sex determination GO:0007530 8 8 0,000 0,03324429 0,07905706 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,03324429 0,07895518 ! plasma membrane fusion GO:0045026 8 8 0,000 0,03324429 0,07885357 ! response to fungus GO:0009620 8 8 0,000 0,03324429 0,07875221 ! stem cell differentiation GO:0048863 8 8 0,000 0,03324429 0,07865112 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,03324429 0,07855028 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,03324429 0,07844971 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,03324429 0,07834939 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,03324429 0,07824932 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,03324429 0,07814952 ! regulation of vasodilation GO:0042312 8 8 0,000 0,03324429 0,07804996 ! vasoconstriction GO:0042310 8 8 0,000 0,03324429 0,07795066 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,03324429 0,07785162 ! muscle cell development GO:0055001 8 8 0,000 0,03324429 0,07775282 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,03324429 0,07765427 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,03324429 0,07755598 ! sensory perception of pain GO:0019233 8 8 0,000 0,03324429 0,07745793 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,03324429 0,07736013 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,03324429 0,07726257 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,03324429 0,07716527 ! chromatin silencing GO:0006342 8 8 0,000 0,03324429 0,0770682 ! tissue regeneration GO:0042246 8 8 0,000 0,03324429 0,07697138 ! salivary gland development GO:0007431 8 8 0,000 0,03324429 0,07687481 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,03324429 0,07677847 ! T cell homeostasis GO:0043029 8 8 0,000 0,03324429 0,07668238 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,03324429 0,07658653 ! peptidyl-serine modification GO:0018209 8 8 0,000 0,03324429 0,07649091 ! water homeostasis GO:0030104 8 8 0,000 0,03324429 0,07639554 ! cofactor transport GO:0051181 8 8 0,000 0,03324429 0,0763004 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,03324429 0,0762055 ! acid secretion GO:0046717 8 8 0,000 0,03324429 0,07611083 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,03324429 0,0760164 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,03324429 0,07592221 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,03324429 0,07582824 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,03324429 0,07573451 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,03324429 0,07564101 ! regulation of RNA stability GO:0043487 8 8 0,000 0,03324429 0,07554774 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,03324429 0,07545471 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,03324429 0,0753619 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,03324429 0,07526931 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,03324429 0,07517696 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,03324429 0,07508483 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,03324429 0,07499293 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,03324429 0,07490125 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,03324429 0,07480979 ! developmental induction GO:0031128 8 8 0,000 0,03324429 0,07471856 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,03324429 0,07462755 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,03324429 0,07453677 ! actin filament polymerization GO:0030041 9 8 0,000 0,03324429 0,0744462 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,03324429 0,07435585 ! peptide hormone processing GO:0016486 8 8 0,000 0,03324429 0,07426572 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,03324429 0,07417581 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,03324429 0,07408612 ! regulation of translation GO:0006417 69 69 1,000 0,03381348 0,07526358 ! sensory perception of sound GO:0007605 71 69 1,000 0,03381348 0,07517279 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 1,000 0,03381348 0,07508222 ! response to nutrient levels GO:0031667 69 69 1,000 0,03381348 0,07499187 ! positive regulation of transport GO:0051050 71 70 1,000 0,0347183 0,07690605 ! growth GO:0040007 70 70 1,000 0,0347183 0,07681372 ! muscle tissue development GO:0060537 72 70 1,000 0,0347183 0,07672162 ! oxidative phosphorylation GO:0006119 71 71 1,000 0,0356326 0,07864776 ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,0356326 0,07855368 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,03655628 0,08049369 ! lactation GO:0007595 10 9 0,000 0,03732402 0,08208612 ! embryonic pattern specification GO:0009880 10 9 0,000 0,03732402 0,08198828 ! positive regulation of cell size GO:0045793 9 9 0,000 0,03732402 0,08189067 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,03732402 0,0817933 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,03732402 0,08169616 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,03732402 0,08159925 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,03732402 0,08150257 ! viral genome replication GO:0019079 9 9 0,000 0,03732402 0,08140611 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,03732402 0,08130989 ! copper ion transport GO:0006825 9 9 0,000 0,03732402 0,08121389 ! lipid phosphorylation GO:0046834 9 9 0,000 0,03732402 0,08111812 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,03732402 0,08102258 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,03732402 0,08092725 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,03732402 0,08083216 ! RNA polyadenylation GO:0043631 9 9 0,000 0,03732402 0,08073728 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,03732402 0,08064263 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,03732402 0,0805482 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,03732402 0,080454 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,03732402 0,08036001 ! phospholipid efflux GO:0033700 9 9 0,000 0,03732402 0,08026624 ! response to alkaloid GO:0043279 10 9 0,000 0,03732402 0,08017269 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,03732402 0,08007936 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,03732402 0,07998624 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,03732402 0,07989334 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,03732402 0,07980066 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,03732402 0,07970819 ! response to ethanol GO:0045471 9 9 0,000 0,03732402 0,07961593 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,03732402 0,07952389 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,03732402 0,07943206 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,03732402 0,07934045 ! methionine metabolic process GO:0006555 9 9 0,000 0,03732402 0,07924904 ! glutamine metabolic process GO:0006541 9 9 0,000 0,03732402 0,07915784 ! cerebral cortex development GO:0021987 9 9 0,000 0,03732402 0,07906686 ! response to osmotic stress GO:0006970 9 9 0,000 0,03732402 0,07897608 ! pigmentation during development GO:0048066 9 9 0,000 0,03732402 0,07888551 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,03732402 0,07879515 ! central nervous system neuron development GO:0021954 10 9 0,000 0,03732402 0,078705 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,03732402 0,07861505 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,03732402 0,0785253 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,03732402 0,07843577 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,03732402 0,07834643 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,03732402 0,0782573 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,03732402 0,07816837 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,03732402 0,07807964 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,03732402 0,07799112 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,03732402 0,07790279 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,03732402 0,07781467 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,03732402 0,07772674 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,03732402 0,07763901 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,03732402 0,07755148 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,03732402 0,07746415 ! DNA replication initiation GO:0006270 9 9 0,000 0,03732402 0,07737702 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,03732402 0,07729007 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,03732402 0,07720333 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,03732402 0,07711678 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,03732402 0,07703042 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,03732402 0,07694426 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,03732402 0,07685829 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,03732402 0,07677251 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,03732402 0,07668692 ! negative regulation of tissue remodeling GO:0034104 9 9 0,000 0,03732402 0,07660152 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,03732402 0,07651631 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,03732402 0,0764313 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,03732402 0,07634647 ! collagen catabolic process GO:0030574 9 9 0,000 0,03732402 0,07626183 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,03732402 0,07617737 ! purine base metabolic process GO:0006144 9 9 0,000 0,03732402 0,0760931 ! gas transport GO:0015669 9 9 0,000 0,03732402 0,07600902 ! cholesterol efflux GO:0033344 9 9 0,000 0,03732402 0,07592513 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,03732402 0,07584142 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,03732402 0,07575789 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,03732402 0,07567455 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,03732402 0,07559139 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,03732402 0,07550842 ! defense response to virus GO:0051607 9 9 0,000 0,03732402 0,07542562 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,03732402 0,07534301 ! actin filament-based movement GO:0030048 9 9 0,000 0,03732402 0,07526058 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,03732402 0,07517832 ! electron transport chain GO:0022900 75 74 1,000 0,03843143 0,07732438 ! purine ribonucleotide metabolic process GO:0009150 75 75 1,000 0,03938273 0,07915199 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,04034306 0,08099374 ! cell morphogenesis involved in differentiation GO:0000904 82 77 1,000 0,04131233 0,08284942 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,04138713 0,08290921 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,04138713 0,08281919 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,04138713 0,08272936 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,04138713 0,08263973 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,04138713 0,08255029 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,04138713 0,08246105 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,04138713 0,082372 ! neuron maturation GO:0042551 10 10 0,000 0,04138713 0,08228314 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,04138713 0,08219447 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,04138713 0,082106 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,04138713 0,08201771 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,04138713 0,08192961 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,04138713 0,08184171 ! hormone secretion GO:0046879 10 10 0,000 0,04138713 0,08175399 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,04138713 0,08166646 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,04138713 0,08157911 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,04138713 0,08149196 ! cAMP metabolic process GO:0046058 10 10 0,000 0,04138713 0,08140499 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,04138713 0,0813182 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,04138713 0,0812316 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,04138713 0,08114518 ! glial cell development GO:0021782 10 10 0,000 0,04138713 0,08105895 ! phototransduction GO:0007602 11 10 0,000 0,04138713 0,0809729 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,04138713 0,08088703 ! fat cell differentiation GO:0045444 10 10 0,000 0,04138713 0,08080135 ! myoblast differentiation GO:0045445 10 10 0,000 0,04138713 0,08071584 ! centrosome cycle GO:0007098 10 10 0,000 0,04138713 0,08063052 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,04138713 0,08054538 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,04138713 0,08046041 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,04138713 0,08037563 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,04138713 0,08029102 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,04138713 0,08020659 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,04138713 0,08012234 ! protein polyubiquitination GO:0000209 10 10 0,000 0,04138713 0,08003827 ! glutamate metabolic process GO:0006536 11 10 0,000 0,04138713 0,07995437 ! plasma membrane organization GO:0007009 10 10 0,000 0,04138713 0,07987065 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,04138713 0,0797871 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,04138713 0,07970373 ! lysosomal transport GO:0007041 10 10 0,000 0,04138713 0,07962053 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,04138713 0,07953751 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,04138713 0,07945466 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,04138713 0,07937198 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,04138713 0,07928947 ! exocrine system development GO:0035272 10 10 0,000 0,04138713 0,07920714 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,04138713 0,07912497 ! neuromuscular junction development GO:0007528 10 10 0,000 0,04138713 0,07904298 ! embryo implantation GO:0007566 11 10 0,000 0,04138713 0,07896115 ! regulation of protein binding GO:0043393 11 10 0,000 0,04138713 0,07887949 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,04138713 0,07879801 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,04138713 0,07871669 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,04138713 0,07863554 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,04138713 0,07855455 ! protein export from nucleus GO:0006611 10 10 0,000 0,04138713 0,07847374 ! negative regulation of immune response GO:0050777 10 10 0,000 0,04138713 0,07839308 ! cytolysis GO:0019835 10 10 0,000 0,04138713 0,0783126 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,04138713 0,07823228 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,04138713 0,07815212 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,04138713 0,07807213 ! histone deacetylation GO:0016575 10 10 0,000 0,04138713 0,0779923 ! mRNA splice site selection GO:0006376 11 10 0,000 0,04138713 0,07791264 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,04138713 0,07783313 ! gland morphogenesis GO:0022612 10 10 0,000 0,04138713 0,07775379 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,04138713 0,07767461 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,04138713 0,0775956 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,04138713 0,07751674 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,04138713 0,07743804 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,04138713 0,0773595 ! regulation of epidermis development GO:0045682 10 10 0,000 0,04138713 0,07728113 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,04138713 0,07720291 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,04138713 0,07712484 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,04138713 0,07704694 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,04138713 0,07696919 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,04138713 0,0768916 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,04138713 0,07681417 ! nerve development GO:0021675 10 10 0,000 0,04138713 0,07673689 ! gut development GO:0048565 10 10 0,000 0,04138713 0,07665977 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,04138713 0,0765828 ! negative regulation of homeostatic process GO:0032845 10 10 0,000 0,04138713 0,07650599 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,04138713 0,07642933 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,04138713 0,07635282 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,04138713 0,07627647 ! regulation of protein modification process GO:0031399 79 78 1,000 0,04229045 0,07786344 ! nuclear transport GO:0051169 79 79 1,000 0,04327735 0,07960096 GO:0006913|nucleocytoplasmic transport, ! tube development GO:0035295 83 81 1,000 0,04527711 0,08319613 ! lymphocyte activation GO:0046649 82 81 1,000 0,04527711 0,08311326 ! protein secretion GO:0009306 11 11 0,000 0,04543367 0,08331767 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,04543367 0,08323485 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,04543367 0,08315219 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,04543367 0,0830697 ! negative regulation of defense response GO:0031348 11 11 0,000 0,04543367 0,08298737 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,04543367 0,0829052 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,04543367 0,0828232 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,04543367 0,08274136 ! skin development GO:0043588 11 11 0,000 0,04543367 0,08265968 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,04543367 0,08257816 ! signal complex assembly GO:0007172 11 11 0,000 0,04543367 0,0824968 ! microtubule-based transport GO:0010970 11 11 0,000 0,04543367 0,08241561 ! endothelial cell migration GO:0043542 11 11 0,000 0,04543367 0,08233457 ! peroxisomal transport GO:0043574 11 11 0,000 0,04543367 0,08225369 ! protein amino acid methylation GO:0006479 11 11 0,000 0,04543367 0,08217297 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,04543367 0,08209241 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,04543367 0,082012 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,04543367 0,08193176 ! T cell proliferation GO:0042098 11 11 0,000 0,04543367 0,08185167 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,04543367 0,08177173 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,04543367 0,08169196 ! regulation of viral genome replication GO:0045069 11 11 0,000 0,04543367 0,08161234 ! spinal cord development GO:0021510 11 11 0,000 0,04543367 0,08153287 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,04543367 0,08145356 ! smooth muscle contraction GO:0006939 11 11 0,000 0,04543367 0,0813744 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,04543367 0,08129539 ! digestive system process GO:0022600 11 11 0,000 0,04543367 0,08121654 ! mitotic spindle organization GO:0007052 11 11 0,000 0,04543367 0,08113785 ! fucose metabolic process GO:0006004 11 11 0,000 0,04543367 0,0810593 ! membrane budding GO:0006900 11 11 0,000 0,04543367 0,08098091 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,04543367 0,08090266 ! monoamine transport GO:0015844 11 11 0,000 0,04543367 0,08082457 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,04543367 0,08074663 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,04543367 0,08066884 ! body fluid secretion GO:0007589 11 11 0,000 0,04543367 0,0805912 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,04543367 0,08051371 ! intermediate filament-based process GO:0045103 11 11 0,000 0,04543367 0,08043637 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,04543367 0,08035917 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,04543367 0,08028212 ! membrane depolarization GO:0051899 11 11 0,000 0,04543367 0,08020523 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,04543367 0,08012847 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,04543367 0,08005187 ! oogenesis GO:0048477 11 11 0,000 0,04543367 0,07997541 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,04543367 0,0798991 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,04543367 0,07982293 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,04543367 0,07974691 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,04543367 0,07967103 ! muscle maintenance GO:0046716 12 11 0,000 0,04543367 0,0795953 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,04543367 0,07951971 ! hindbrain development GO:0030902 11 11 0,000 0,04543367 0,07944427 ! steroid catabolic process GO:0006706 11 11 0,000 0,04543367 0,07936896 ! endocrine process GO:0050886 11 11 0,000 0,04543367 0,0792938 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,04543367 0,07921879 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,04543367 0,07914391 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,04543367 0,07906917 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,04543367 0,07899458 ! negative regulation of lymphocyte activation GO:0051250 11 11 0,000 0,04543367 0,07892013 ! ribonucleotide metabolic process GO:0009259 83 83 1,000 0,04731093 0,08210362 ! blood vessel morphogenesis GO:0048514 84 83 1,000 0,04731093 0,08202639 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,0483404 0,08373249 ! nitrogen compound biosynthetic process GO:0044271 86 85 1,000 0,04937814 0,08544968 ! translational initiation GO:0006413 12 12 0,000 0,04946372 0,08551749 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,04946372 0,08543734 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,04946372 0,08535734 ! initiation of viral infection GO:0019059 12 12 0,000 0,04946372 0,08527749 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,04946372 0,0851978 ! iron ion transport GO:0006826 13 12 0,000 0,04946372 0,08511825 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,04946372 0,08503884 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,04946372 0,08495959 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,04946372 0,08488049 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,04946372 0,08480153 ! collagen metabolic process GO:0032963 12 12 0,000 0,04946372 0,08472271 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,04946372 0,08464405 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,04946372 0,08456553 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,04946372 0,08448716 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,04946372 0,08440893 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,04946372 0,08433084 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,04946372 0,0842529 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,04946372 0,08417511 ! actomyosin structure organization GO:0031032 12 12 0,000 0,04946372 0,08409745 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,04946372 0,08401995 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,04946372 0,08394258 ! retinoid metabolic process GO:0001523 12 12 0,000 0,04946372 0,08386536 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,04946372 0,08378827 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,04946372 0,08371133 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,04946372 0,08363453 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,04946372 0,08355787 ! acute-phase response GO:0006953 12 12 0,000 0,04946372 0,08348136 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,04946372 0,08340498 ! vacuolar transport GO:0007034 12 12 0,000 0,04946372 0,08332874 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,04946372 0,08325264 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,04946372 0,08317668 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,04946372 0,08310086 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,04946372 0,08302517 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,04946372 0,08294963 ! male gonad development GO:0008584 12 12 0,000 0,04946372 0,08287422 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,04946372 0,08279895 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,04946372 0,08272381 ! renal system process GO:0003014 12 12 0,000 0,04946372 0,08264881 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,04946372 0,08257395 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,04946372 0,08249922 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,04946372 0,08242463 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,04946372 0,08235017 ! pallium development GO:0021543 13 12 0,000 0,04946372 0,08227585 ! cell fate determination GO:0001709 12 12 0,000 0,04946372 0,08220166 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,04946372 0,0821276 ! G1 phase GO:0051318 13 12 0,000 0,04946372 0,08205368 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,04946372 0,08197989 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,04946372 0,08190624 ! detection of light stimulus GO:0009583 13 12 0,000 0,04946372 0,08183271 ! synaptogenesis GO:0007416 12 12 0,000 0,04946372 0,08175932 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,04946372 0,08168606 ! hormone transport GO:0009914 12 12 0,000 0,04946372 0,08161293 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,04946372 0,08153993 ! heme biosynthetic process GO:0006783 12 12 0,000 0,04946372 0,08146706 ! spermatid differentiation GO:0048515 13 12 0,000 0,04946372 0,08139432 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,04946372 0,08132171 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,04946372 0,08124923 ! neural tube closure GO:0001843 13 12 0,000 0,04946372 0,08117688 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,04946372 0,08110466 ! positive regulation of protein kinase activity GO:0045860 89 86 1,000 0,05042406 0,08260581 ! organophosphate metabolic process GO:0019637 87 86 1,000 0,05042406 0,08253245 GO:0006644|phospholipid metabolic process, ! male gamete generation GO:0048232 90 88 1,000 0,05254011 0,08591963 GO:0007283|spermatogenesis, ! positive regulation of transferase activity GO:0051347 91 88 1,000 0,05254011 0,08584346 GO:0033674|positive regulation of kinase activity, ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,05347734 0,08729738 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,05347734 0,08722013 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,05347734 0,08714301 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,05347734 0,08706603 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,05347734 0,08698918 ! gluconeogenesis GO:0006094 13 13 0,000 0,05347734 0,08691247 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,05347734 0,0868359 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,05347734 0,08675946 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,05347734 0,08668315 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,05347734 0,08660698 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,05347734 0,08653094 ! regeneration GO:0031099 13 13 0,000 0,05347734 0,08645504 ! keratinization GO:0031424 13 13 0,000 0,05347734 0,08637927 ! post-embryonic development GO:0009791 14 13 0,000 0,05347734 0,08630363 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,05347734 0,08622812 ! patterning of blood vessels GO:0001569 13 13 0,000 0,05347734 0,08615275 ! vasculogenesis GO:0001570 13 13 0,000 0,05347734 0,08607751 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,05347734 0,0860024 ! regulation of innate immune response GO:0045088 13 13 0,000 0,05347734 0,08592742 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,05347734 0,08585257 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,05347734 0,08577785 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,05347734 0,08570326 ! autophagy GO:0006914 13 13 0,000 0,05347734 0,0856288 ! receptor metabolic process GO:0043112 14 13 0,000 0,05347734 0,08555447 ! actin filament bundle formation GO:0051017 13 13 0,000 0,05347734 0,08548026 ! ureteric bud development GO:0001657 13 13 0,000 0,05347734 0,08540619 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,05347734 0,08533225 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,05347734 0,08525843 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,05347734 0,08518474 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,05347734 0,08511118 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,05347734 0,08503774 ! regulation of viral reproduction GO:0050792 13 13 0,000 0,05347734 0,08496444 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,05347734 0,08489125 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,05347734 0,0848182 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,05347734 0,08474527 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,05347734 0,08467246 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,05347734 0,08459978 ! vasodilation GO:0042311 14 13 0,000 0,05347734 0,08452723 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,05347734 0,08445479 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,05347734 0,08438249 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,05347734 0,0843103 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,05347734 0,08423824 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,05347734 0,08416631 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,05347734 0,08409449 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,05347734 0,0840228 ! immunoglobulin production GO:0002377 13 13 0,000 0,05347734 0,08395123 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,05347734 0,08387978 ! negative regulation of leukocyte activation GO:0002695 13 13 0,000 0,05347734 0,08380846 ! cell-cell junction organization GO:0045216 13 13 0,000 0,05347734 0,08373725 ! regulation of cell-substrate adhesion GO:0010810 14 13 0,000 0,05347734 0,08366617 GO:0001952|regulation of cell-matrix adhesion, ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,05347734 0,0835952 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,05347734 0,08352436 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,05347734 0,08345364 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,05347734 0,08338303 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,05347734 0,08331255 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,05347734 0,08324218 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,05347734 0,08317194 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,05347734 0,08310181 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,05347734 0,0830318 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,05347734 0,08296191 ! blastocyst development GO:0001824 13 13 0,000 0,05347734 0,08289213 ! telomere organization GO:0032200 13 13 0,000 0,05347734 0,08282248 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,05347734 0,08275293 ! regulation of amine transport GO:0051952 13 13 0,000 0,05347734 0,08268351 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,05347734 0,0826142 ! chemotaxis GO:0006935 90 89 1,000 0,05361008 0,0827499 GO:0042330|taxis, ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 0,05468791 0,08434294 ! brain development GO:0007420 91 90 1,000 0,05468791 0,08427242 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,05686682 0,08755684 ! neuron fate commitment GO:0048663 14 14 0,000 0,0574746 0,08841877 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,0574746 0,08834503 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,0574746 0,08827141 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,0574746 0,08819791 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,0574746 0,08812453 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,0574746 0,08805128 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,0574746 0,08797815 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,0574746 0,08790514 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,0574746 0,08783225 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,0574746 0,08775948 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,0574746 0,08768683 ! vesicle docking GO:0048278 14 14 0,000 0,0574746 0,0876143 ! superoxide metabolic process GO:0006801 15 14 0,000 0,0574746 0,08754189 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,0574746 0,0874696 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,0574746 0,08739743 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,0574746 0,08732538 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,0574746 0,08725345 ! hair cycle GO:0042633 14 14 0,000 0,0574746 0,08718164 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,0574746 0,08710994 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,0574746 0,08703836 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,0574746 0,0869669 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,0574746 0,08689556 ! lysosome organization GO:0007040 14 14 0,000 0,0574746 0,08682433 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,0574746 0,08675323 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,0574746 0,08668223 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,0574746 0,08661136 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,0574746 0,0865406 ! primary neural tube formation GO:0014020 15 14 0,000 0,0574746 0,08646995 ! peptide cross-linking GO:0018149 14 14 0,000 0,0574746 0,08639942 ! regulation of behavior GO:0050795 14 14 0,000 0,0574746 0,086329 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,0574746 0,0862587 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,0574746 0,08618852 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,0574746 0,08611845 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,0574746 0,08604849 ! formation of primary germ layer GO:0001704 14 14 0,000 0,0574746 0,08597864 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,0574746 0,08590891 ! collagen fibril organization GO:0030199 14 14 0,000 0,0574746 0,08583929 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,0574746 0,08576979 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,0574746 0,0857004 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,0574746 0,08563111 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,0574746 0,08556195 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,0574746 0,08549289 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,0574746 0,08542394 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,0574746 0,08535511 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,0574746 0,08528638 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,0574746 0,08521777 ! blood vessel development GO:0001568 95 94 1,000 0,05907619 0,08752205 ! vasculature development GO:0001944 97 96 1,000 0,06131542 0,09076652 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,06145556 0,09090095 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,06145556 0,09082806 ! positive regulation of ossification GO:0045778 15 15 0,000 0,06145556 0,09075528 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,06145556 0,09068262 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,06145556 0,09061007 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,06145556 0,09053764 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,06145556 0,09046533 ! response to vitamin GO:0033273 15 15 0,000 0,06145556 0,09039313 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,06145556 0,09032104 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,06145556 0,09024907 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,06145556 0,09017722 ! insulin receptor signaling pathway GO:0008286 17 15 0,000 0,06145556 0,09010548 ! ovarian follicle development GO:0001541 15 15 0,000 0,06145556 0,09003385 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,06145556 0,08996234 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,06145556 0,08989094 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,06145556 0,08981966 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,06145556 0,08974849 ! heme metabolic process GO:0042168 15 15 0,000 0,06145556 0,08967743 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,06145556 0,08960648 ! chromosome condensation GO:0030261 15 15 0,000 0,06145556 0,08953564 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,06145556 0,08946492 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,06145556 0,08939431 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,06145556 0,08932381 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,06145556 0,08925342 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,06145556 0,08918314 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,06145556 0,08911297 ! phospholipid transport GO:0015914 15 15 0,000 0,06145556 0,08904292 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,06145556 0,08897297 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,06145556 0,08890313 ! glutathione metabolic process GO:0006749 16 15 0,000 0,06145556 0,0888334 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,06145556 0,08876378 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,06145556 0,08869427 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,06145556 0,08862487 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,06145556 0,08855558 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,06145556 0,0884864 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,06145556 0,08841732 ! negative regulation of cell activation GO:0050866 15 15 0,000 0,06145556 0,08834835 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,06145556 0,08827949 ! endocytosis GO:0006897 99 98 1,000 0,06358387 0,09126563 GO:0010324|membrane invagination, ! anti-apoptosis GO:0006916 100 99 1,000 0,06472886 0,0928368 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,06542027 0,09375549 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,06542027 0,09368264 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,06542027 0,09360991 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,06542027 0,09353729 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,06542027 0,09346478 ! learning GO:0007612 16 16 0,000 0,06542027 0,09339238 ! circadian rhythm GO:0007623 16 16 0,000 0,06542027 0,0933201 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,06542027 0,09324792 ! vacuole organization GO:0007033 16 16 0,000 0,06542027 0,09317586 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,06542027 0,09310391 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,06542027 0,09303207 ! vesicle targeting GO:0006903 17 16 0,000 0,06542027 0,09296034 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,06542027 0,09288872 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,06542027 0,09281722 ! iron ion homeostasis GO:0055072 16 16 0,000 0,06542027 0,09274582 ! positive regulation of cell development GO:0010720 16 16 0,000 0,06542027 0,09267453 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,06542027 0,09260335 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,06542027 0,09253228 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,06542027 0,09246132 ! cell fate specification GO:0001708 16 16 0,000 0,06542027 0,09239047 ! pentose metabolic process GO:0019321 16 16 0,000 0,06542027 0,09231973 ! fatty acid transport GO:0015908 16 16 0,000 0,06542027 0,09224909 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,06542027 0,09217857 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,06542027 0,09210815 ! cofactor catabolic process GO:0051187 16 16 0,000 0,06542027 0,09203783 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,06542027 0,09196763 ! polyol metabolic process GO:0019751 16 16 0,000 0,06542027 0,09189753 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,06542027 0,09182754 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,06542027 0,09175766 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,06542027 0,09168788 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,06542027 0,09161821 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,06542027 0,09154864 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,06542027 0,09147918 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,06542027 0,09140983 ! regulation of coagulation GO:0050818 17 16 0,000 0,06542027 0,09134058 ! response to hormone stimulus GO:0009725 102 100 1,000 0,06588093 0,09191412 ! muscle organ development GO:0007517 102 100 1,000 0,06588093 0,0918446 ! hemopoiesis GO:0030097 104 100 1,000 0,06588093 0,09177517 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,06936882 0,09656098 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,06936882 0,0964881 ! positive regulation of cell adhesion GO:0045785 17 17 0,000 0,06936882 0,09641533 ! myelination GO:0042552 17 17 0,000 0,06936882 0,09634268 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,06936882 0,09627013 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,06936882 0,09619769 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,06936882 0,09612536 ! leukocyte adhesion GO:0007159 17 17 0,000 0,06936882 0,09605314 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,06936882 0,09598103 ! sensory perception of smell GO:0007608 17 17 0,000 0,06936882 0,09590903 ! glucose transport GO:0015758 17 17 0,000 0,06936882 0,09583713 ! cell junction assembly GO:0034329 18 17 0,000 0,06936882 0,09576534 ! tissue remodeling GO:0048771 17 17 0,000 0,06936882 0,09569366 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,06936882 0,09562209 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,06936882 0,09555062 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,06936882 0,09547926 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,06936882 0,09540801 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,06936882 0,09533686 ! neural crest cell development GO:0014032 19 17 0,000 0,06936882 0,09526582 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,06936882 0,09519489 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,06936882 0,09512406 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,06936882 0,09505333 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,06936882 0,09498271 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,06936882 0,0949122 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,06936882 0,09484179 ! pigmentation GO:0043473 17 17 0,000 0,06936882 0,09477148 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,06936882 0,09470128 ! adult locomotory behavior GO:0008344 17 17 0,000 0,06936882 0,09463119 ! embryonic organ development GO:0048568 17 17 0,000 0,06936882 0,09456119 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,06936882 0,0944913 ! liver development GO:0001889 17 17 0,000 0,06936882 0,09442152 ! gene silencing GO:0016458 17 17 0,000 0,06936882 0,09435183 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,07330125 0,099627 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,07330125 0,09955358 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,07330125 0,09948027 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,07330125 0,09940707 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,07330125 0,09933398 ! membrane docking GO:0022406 18 18 0,000 0,07330125 0,09926099 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,07330125 0,09918811 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,07330125 0,09911534 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,07330125 0,09904268 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,07330125 0,09897012 ! hexose transport GO:0008645 18 18 0,000 0,07330125 0,09889766 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,07330125 0,09882532 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,07330125 0,09875308 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,07330125 0,09868094 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,07330125 0,09860891 ! ceramide metabolic process GO:0006672 18 18 0,000 0,07330125 0,09853699 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,07330125 0,09846517 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,07330125 0,09839345 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,07330125 0,09832184 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,07330125 0,09825033 ! ensheathment of neurons GO:0007272 18 18 0,000 0,07330125 0,09817893 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 18 18 0,000 0,07330125 0,09810763 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,07330125 0,09803644 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,07330125 0,09796534 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,07330125 0,09789436 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,07721764 0,10305005 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,07721764 0,10297548 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,07721764 0,10290102 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,07721764 0,10282667 ! feeding behavior GO:0007631 19 19 0,000 0,07721764 0,10275243 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,07721764 0,10267829 ! peroxisome organization GO:0007031 19 19 0,000 0,07721764 0,10260427 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,07721764 0,10253034 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,07721764 0,10245653 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,07721764 0,10238282 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,07721764 0,10230921 ! metanephros development GO:0001656 19 19 0,000 0,07721764 0,10223572 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,07721764 0,10216232 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,07721764 0,10208904 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,07721764 0,10201585 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,07721764 0,10194278 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,07721764 0,1018698 ! peripheral nervous system development GO:0007422 19 19 0,000 0,07721764 0,10179694 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,07721764 0,10172417 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,07721764 0,10165151 ! eye morphogenesis GO:0048592 19 19 0,000 0,07721764 0,10157895 ! regulation of cell shape GO:0008360 21 19 0,000 0,07721764 0,1015065 ! placenta development GO:0001890 19 19 0,000 0,07721764 0,10143415 ! response to heat GO:0009408 19 19 0,000 0,07721764 0,10136191 ! vesicle localization GO:0051648 20 19 0,000 0,07721764 0,10128976 ! regulation of muscle development GO:0048634 21 20 0,000 0,08111805 0,10633042 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,08111805 0,10625484 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,08111805 0,10617938 ! negative regulation of binding GO:0051100 21 20 0,000 0,08111805 0,10610402 ! organic ether metabolic process GO:0018904 20 20 0,000 0,08111805 0,10602877 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,08111805 0,10595362 ! neural tube development GO:0021915 21 20 0,000 0,08111805 0,10587859 ! nucleus organization GO:0006997 20 20 0,000 0,08111805 0,10580366 ! phagocytosis GO:0006909 21 20 0,000 0,08111805 0,10572883 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,08111805 0,10565411 ! protein targeting to membrane GO:0006612 22 20 0,000 0,08111805 0,10557949 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,08111805 0,10550499 ! chromatin remodeling GO:0006338 20 20 0,000 0,08111805 0,10543058 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,08111805 0,10535628 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,08111805 0,10528209 ! lipid oxidation GO:0034440 20 20 0,000 0,08111805 0,105208 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,08111805 0,10513401 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,08111805 0,10506013 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,08111805 0,10498635 ! RNA modification GO:0009451 20 20 0,000 0,08111805 0,10491268 ! single fertilization GO:0007338 21 20 0,000 0,08111805 0,10483911 ! regulation of B cell activation GO:0050864 20 20 0,000 0,08111805 0,10476564 ! mRNA catabolic process GO:0006402 21 21 0,000 0,08500254 0,10970565 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,08500254 0,10962888 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 0,000 0,08500254 0,10955222 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,08500254 0,10947566 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,08500254 0,10939921 ! Notch signaling pathway GO:0007219 22 21 0,000 0,08500254 0,10932287 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,08500254 0,10924663 ! ear morphogenesis GO:0042471 21 21 0,000 0,08500254 0,1091705 ! organic anion transport GO:0015711 21 21 0,000 0,08500254 0,10909448 ! cholesterol transport GO:0030301 21 21 0,000 0,08500254 0,10901856 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,08500254 0,10894275 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,08500254 0,10886704 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,08500254 0,10879144 ! regulation of action potential in neuron GO:0019228 21 21 0,000 0,08500254 0,10871594 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,08500254 0,10864055 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,08500254 0,10856526 ! regulation of proteolysis GO:0030162 21 21 0,000 0,08500254 0,10849008 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,08500254 0,108415 ! cellular response to insulin stimulus GO:0032869 23 21 0,000 0,08500254 0,10834002 ! RNA export from nucleus GO:0006405 22 22 0,000 0,08887116 0,11319251 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,08887116 0,11311433 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,08887116 0,11303627 ! regulation of ion transport GO:0043269 22 22 0,000 0,08887116 0,11295831 ! cell junction organization GO:0034330 23 22 0,000 0,08887116 0,11288047 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,08887116 0,11280272 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,08887116 0,11272509 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,08887116 0,11264756 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,08887116 0,11257014 ! ovulation cycle process GO:0022602 22 22 0,000 0,08887116 0,11249283 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,08887116 0,11241562 ! cell chemotaxis GO:0060326 23 22 0,000 0,08887116 0,11233852 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,08887116 0,11226152 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,08887116 0,11218463 ! male sex differentiation GO:0046661 22 22 0,000 0,08887116 0,11210784 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,08887116 0,11203116 ! biopolymer methylation GO:0043414 22 22 0,000 0,08887116 0,11195458 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,08887116 0,11187811 ! detection of external stimulus GO:0009581 23 22 0,000 0,08887116 0,11180174 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,08887116 0,11172548 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,08887116 0,11164932 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,08887116 0,11157327 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,08887116 0,11149732 ! cytokine production GO:0001816 22 22 0,000 0,08887116 0,11142147 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,08887116 0,11134572 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,092724 0,11609397 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,092724 0,11601516 ! viral infectious cycle GO:0019058 23 23 0,000 0,092724 0,11593645 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,092724 0,11585785 ! response to estrogen stimulus GO:0043627 23 23 0,000 0,092724 0,11577936 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,092724 0,11570097 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,092724 0,11562269 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,092724 0,11554451 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,092724 0,11546644 ! endocrine system development GO:0035270 23 23 0,000 0,092724 0,11538847 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,092724 0,11531061 ! positive regulation of growth GO:0045927 23 23 0,000 0,092724 0,11523286 ! female gonad development GO:0008585 23 23 0,000 0,092724 0,11515521 ! lipid homeostasis GO:0055088 23 23 0,000 0,092724 0,11507766 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,092724 0,11500022 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,092724 0,11492288 ! regulation of action potential GO:0001508 24 24 0,000 0,0965611 0,11959819 ! gliogenesis GO:0042063 24 24 0,000 0,0965611 0,11951787 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,0965611 0,11943766 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,0965611 0,11935755 ! glucose homeostasis GO:0042593 24 24 0,000 0,0965611 0,11927755 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,0965611 0,11919766 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,0965611 0,11911788 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,0965611 0,1190382 ! ovulation cycle GO:0042698 24 24 0,000 0,0965611 0,11895863 ! fertilization GO:0009566 25 24 0,000 0,0965611 0,11887916 ! maintenance of protein location GO:0045185 25 24 0,000 0,0965611 0,1187998 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,0965611 0,11872055 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,0965611 0,1186414 ! glucan metabolic process GO:0044042 25 24 0,000 0,0965611 0,11856236 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,10038253 0,12317244 ! negative regulation of secretion GO:0051048 26 25 0,000 0,10038253 0,12309049 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,10038253 0,12300865 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,10038253 0,12292691 ! cellular component disassembly GO:0022411 26 25 0,000 0,10038253 0,12284529 ! endosome transport GO:0016197 25 25 0,000 0,10038253 0,12276377 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,10038253 0,12268236 ! development of primary female sexual characteristics GO:0046545 25 25 0,000 0,10038253 0,12260106 GO:0046660|female sex differentiation, ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,10038253 0,12251987 ! regulation of T cell proliferation GO:0042129 25 25 0,000 0,10038253 0,12243878 ! excretion GO:0007588 25 25 0,000 0,10038253 0,12235781 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,10038253 0,12227694 ! gastrulation GO:0007369 25 25 0,000 0,10038253 0,12219617 ! heart morphogenesis GO:0003007 25 25 0,000 0,10038253 0,12211551 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,10038253 0,12203496 ! regulation of endocytosis GO:0030100 25 25 0,000 0,10038253 0,12195452 ! negative regulation of immune system process GO:0002683 25 25 0,000 0,10038253 0,12187418 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,10038253 0,12179395 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,10038253 0,12171382 ! positive regulation of defense response GO:0031349 26 26 0,000 0,10418835 0,12624532 ! glycolysis GO:0006096 26 26 0,000 0,10418835 0,12616237 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,10418835 0,12607954 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,10418835 0,12599681 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,10418835 0,12591419 ! cellular defense response GO:0006968 26 26 0,000 0,10418835 0,12583167 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,10418835 0,12574927 ! regulation of T cell differentiation GO:0045580 26 26 0,000 0,10418835 0,12566697 ! regulation of protein secretion GO:0050708 26 26 0,000 0,10418835 0,12558478 ! germ cell development GO:0007281 27 26 0,000 0,10418835 0,1255027 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,10418835 0,12542073 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,10418835 0,12533886 ! response to insulin stimulus GO:0032868 28 26 0,000 0,10418835 0,1252571 ! maintenance of location in cell GO:0051651 27 26 0,000 0,10418835 0,12517545 ! synapse organization GO:0050808 26 26 0,000 0,10418835 0,1250939 ! chloride transport GO:0006821 27 27 0,000 0,10797863 0,12956029 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,10797863 0,129476 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,10797863 0,12939181 ! learning or memory GO:0007611 28 27 0,000 0,10797863 0,12930774 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,10797863 0,12922377 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,10797863 0,12913991 ! peptide metabolic process GO:0006518 29 27 0,000 0,10797863 0,12905617 ! inner ear development GO:0048839 27 27 0,000 0,10797863 0,12897253 ! defense response to bacterium GO:0042742 27 27 0,000 0,10797863 0,12888899 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,10797863 0,12880557 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,10797863 0,12872226 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,11175341 0,1331361 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,11175341 0,13305009 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,11175341 0,1329642 ! carbohydrate transport GO:0008643 28 28 0,000 0,11175341 0,13287841 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,11175341 0,13279274 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,11175341 0,13270718 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,11175341 0,13262173 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,11175341 0,13253638 ! developmental growth GO:0048589 28 28 0,000 0,11175341 0,13245115 ! regulation of mast cell proliferation GO:0070666 28 28 0,000 0,11175341 0,13236603 ! cartilage development GO:0051216 29 28 0,000 0,11175341 0,13228102 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,11551278 0,13664316 ! viral reproductive process GO:0022415 29 29 0,000 0,11551278 0,13655551 ! leukocyte migration GO:0050900 30 29 0,000 0,11551278 0,13646798 ! branching morphogenesis of a tube GO:0048754 29 29 0,000 0,11551278 0,13638056 ! regulation of lymphocyte proliferation GO:0050670 29 29 0,000 0,11551278 0,13629324 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! antigen processing and presentation GO:0019882 29 29 0,000 0,11551278 0,13620604 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,11551278 0,13611896 ! tRNA processing GO:0008033 29 29 0,000 0,11551278 0,13603198 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,11551278 0,13594511 ! adult behavior GO:0030534 30 29 0,000 0,11551278 0,13585836 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,11551278 0,13577171 ! transition metal ion transport GO:0000041 31 30 0,000 0,11925677 0,140083 ! RNA catabolic process GO:0006401 30 30 0,000 0,11925677 0,13999378 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,11925677 0,13990467 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,11925677 0,13981567 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,11925677 0,13972679 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,11925677 0,13963801 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,11925677 0,13954936 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,11925677 0,13946081 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,11925677 0,13937237 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,11925677 0,13928405 ! response to temperature stimulus GO:0009266 30 30 0,000 0,11925677 0,13919584 ! regulation of ossification GO:0030278 30 30 0,000 0,11925677 0,13910774 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,11925677 0,13901976 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,11925677 0,13893188 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,11925677 0,13884412 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,11925677 0,13875646 ! vesicle organization GO:0016050 30 30 0,000 0,11925677 0,13866892 ! regulation of translational initiation GO:0006446 31 31 0,000 0,12298547 0,14291439 ! skeletal muscle fiber development GO:0048741 31 31 0,000 0,12298547 0,14282433 ! membrane fusion GO:0006944 31 31 0,000 0,12298547 0,14273439 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,12298547 0,14264457 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,12298547 0,14255485 ! ion transmembrane transport GO:0034220 31 31 0,000 0,12298547 0,14246525 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,12298547 0,14237576 ! digestion GO:0007586 31 31 0,000 0,12298547 0,14228639 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,12298547 0,14219713 ! regulation of heart contraction GO:0008016 31 31 0,000 0,12298547 0,14210797 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,12298547 0,14201893 ! camera-type eye development GO:0043010 31 31 0,000 0,12298547 0,14193 ! extracellular matrix organization GO:0030198 31 31 0,000 0,12298547 0,14184119 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,12298547 0,14175248 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,12298547 0,14166389 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,12298547 0,1415754 ! cell redox homeostasis GO:0045454 32 32 0,000 0,12669892 0,14575912 ! muscle fiber development GO:0048747 32 32 0,000 0,12669892 0,14566819 ! glucose catabolic process GO:0006007 32 32 0,000 0,12669892 0,14557737 ! lipid modification GO:0030258 32 32 0,000 0,12669892 0,14548667 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,12669892 0,14539608 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,12669892 0,1453056 ! cell maturation GO:0048469 32 32 0,000 0,12669892 0,14521524 ! morphogenesis of a branching structure GO:0001763 32 32 0,000 0,12669892 0,14512499 ! nuclear export GO:0051168 32 32 0,000 0,12669892 0,14503485 ! regulation of lymphocyte differentiation GO:0045619 32 32 0,000 0,12669892 0,14494482 ! kidney development GO:0001822 32 32 0,000 0,12669892 0,1448549 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,12669892 0,1447651 ! maintenance of location GO:0051235 33 32 0,000 0,12669892 0,14467541 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,13039719 0,1488062 ! amino acid transport GO:0006865 33 33 0,000 0,13039719 0,14871412 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,13039719 0,14862215 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,13039719 0,14853029 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,13039719 0,14843855 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,13039719 0,14834692 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,13039719 0,14825541 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,13039719 0,148164 ! regulation of actin filament length GO:0030832 34 34 0,000 0,13408033 0,15225511 ! regulation of angiogenesis GO:0045765 35 34 0,000 0,13408033 0,15216136 ! regulation of bone remodeling GO:0046850 34 34 0,000 0,13408033 0,15206772 ! response to metal ion GO:0010038 34 34 0,000 0,13408033 0,1519742 ! ear development GO:0043583 34 34 0,000 0,13408033 0,15188079 ! muscle cell differentiation GO:0042692 35 34 0,000 0,13408033 0,1517875 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,13408033 0,15169432 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,13408033 0,15160125 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,13408033 0,1515083 ! regulation of lipid metabolic process GO:0019216 34 34 0,000 0,13408033 0,15141547 ! secondary metabolic process GO:0019748 34 34 0,000 0,13408033 0,15132275 ! response to peptide hormone stimulus GO:0043434 36 34 0,000 0,13408033 0,15123014 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,13408033 0,15113764 ! viral reproduction GO:0016032 34 34 0,000 0,13408033 0,15104526 ! detection of stimulus GO:0051606 36 34 0,000 0,13408033 0,15095299 ! acute inflammatory response GO:0002526 35 35 0,000 0,13774841 0,15498798 ! regulation of cellular component size GO:0032535 35 35 0,000 0,13774841 0,15489342 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,13774841 0,15479897 ! mesoderm development GO:0007498 35 35 0,000 0,13774841 0,15470464 ! multicellular organism reproduction GO:0032504 36 35 0,000 0,13774841 0,15461042 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,13774841 0,15451632 ! regulation of tissue remodeling GO:0034103 35 35 0,000 0,13774841 0,15442233 ! inorganic anion transport GO:0015698 35 35 0,000 0,13774841 0,15432846 ! response to steroid hormone stimulus GO:0048545 35 35 0,000 0,13774841 0,1542347 ! regulation of immune effector process GO:0002697 35 35 0,000 0,13774841 0,15414105 ! hydrogen transport GO:0006818 36 36 0,000 0,14140148 0,15813285 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,14140148 0,15803695 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,14140148 0,15794117 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,14140148 0,15784551 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,14140148 0,15774996 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,14140148 0,15765453 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,14140148 0,15755921 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,14140148 0,15746401 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,14140148 0,15736892 ! gonad development GO:0008406 36 36 0,000 0,14140148 0,15727395 ! activation of immune response GO:0002253 36 36 0,000 0,14140148 0,15717909 ! coagulation GO:0050817 39 36 0,000 0,14140148 0,15708435 GO:0007596|blood coagulation, ! regulation of adenylate cyclase activity GO:0045761 37 37 0,000 0,14503961 0,16102892 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! negative regulation of protein kinase activity GO:0006469 37 37 0,000 0,14503961 0,16093197 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,14503961 0,16083514 ! eye development GO:0001654 37 37 0,000 0,14503961 0,16073843 ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,14503961 0,16064183 ! adaptive immune response GO:0002250 37 37 0,000 0,14503961 0,16054535 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,14866285 0,16445717 ! neurotransmitter transport GO:0006836 40 38 0,000 0,14866285 0,16435851 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,14866285 0,16425998 ! exocytosis GO:0006887 40 38 0,000 0,14866285 0,16416156 ! negative regulation of kinase activity GO:0033673 38 38 0,000 0,14866285 0,16406326 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,14866285 0,16396508 ! hexose catabolic process GO:0019320 38 38 0,000 0,14866285 0,16386701 ! axon guidance GO:0007411 39 38 0,000 0,14866285 0,16376906 ! regulation of neurological system process GO:0031644 38 38 0,000 0,14866285 0,16367123 ! regulation of homeostatic process GO:0032844 38 38 0,000 0,14866285 0,16357352 ! regulation of cAMP biosynthetic process GO:0030817 39 39 0,000 0,15227127 0,16744388 ! hemostasis GO:0007599 42 39 0,000 0,15227127 0,16734404 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,15227127 0,16724431 ! activation of MAPK activity GO:0000187 39 39 0,000 0,15227127 0,1671447 ! response to unfolded protein GO:0006986 39 39 0,000 0,15227127 0,16704521 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,15227127 0,16694584 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,15227127 0,16684658 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,15227127 0,16674745 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,15227127 0,16664843 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,15227127 0,16654953 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,15227127 0,16645074 ! developmental maturation GO:0021700 39 39 0,000 0,15227127 0,16635207 ! limb development GO:0060173 39 39 0,000 0,15227127 0,16625353 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! regulation of cAMP metabolic process GO:0030814 40 40 0,000 0,15586492 0,1700764 ! DNA catabolic process GO:0006308 41 40 0,000 0,15586492 0,16997576 ! negative regulation of transferase activity GO:0051348 40 40 0,000 0,15586492 0,16987525 ! myeloid cell differentiation GO:0030099 42 40 0,000 0,15586492 0,16977485 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 0,000 0,15944385 0,1735706 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! amine catabolic process GO:0009310 42 41 0,000 0,15944385 0,17346813 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,15944385 0,17336579 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,15944385 0,17326357 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,15944385 0,17316147 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,15944385 0,17305949 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,15944385 0,17295763 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 0,000 0,16300813 0,17671999 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,16300813 0,1766161 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,16300813 0,17651233 ! development of primary sexual characteristics GO:0045137 42 42 0,000 0,16300813 0,17640869 ! response to protein stimulus GO:0051789 42 42 0,000 0,16300813 0,17630516 ! one-carbon metabolic process GO:0006730 42 42 0,000 0,16300813 0,17620175 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,16655782 0,17993322 ! alcohol catabolic process GO:0046164 43 43 0,000 0,16655782 0,17982781 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,16655782 0,17972252 ! regulation of nucleotide metabolic process GO:0006140 43 43 0,000 0,16655782 0,17961736 ! humoral immune response GO:0006959 44 44 0,000 0,17009297 0,18332243 ! mRNA transport GO:0051028 44 44 0,000 0,17009297 0,18321528 ! vitamin metabolic process GO:0006766 44 44 0,000 0,17009297 0,18310826 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,17009297 0,18300137 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,17361364 0,18668025 ! phosphoinositide-mediated signaling GO:0048015 45 45 0,000 0,17361364 0,1865714 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,17361364 0,18646267 ! protein processing GO:0016485 45 45 0,000 0,17361364 0,18635407 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,17711989 0,19000696 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,17711989 0,18989643 ! tube morphogenesis GO:0035239 47 46 0,000 0,17711989 0,18978602 ! cellular response to hormone stimulus GO:0032870 48 46 0,000 0,17711989 0,18967575 ! regulation of membrane potential GO:0042391 46 46 0,000 0,17711989 0,1895656 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,18061177 0,19319065 ! regulation of blood pressure GO:0008217 48 47 0,000 0,18061177 0,19307859 ! amine transport GO:0015837 47 47 0,000 0,18061177 0,19296666 ! rhythmic process GO:0048511 47 47 0,000 0,18061177 0,19285486 ! calcium ion transport GO:0006816 48 48 0,000 0,18408935 0,19645435 ! actin filament organization GO:0007015 50 48 0,000 0,18408935 0,19634066 ! DNA recombination GO:0006310 48 48 0,000 0,18408935 0,1962271 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,18755267 0,19980322 ! divalent metal ion transport GO:0070838 49 49 0,000 0,18755267 0,19968779 ! response to nutrient GO:0007584 49 49 0,000 0,18755267 0,1995725 ! response to bacterium GO:0009617 50 49 0,000 0,18755267 0,19945734 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,18755267 0,19934231 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,18755267 0,19922741 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,19100179 0,20277437 ! chromatin assembly GO:0031497 50 50 0,000 0,19100179 0,20265763 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,19100179 0,20254103 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,19100179 0,20242456 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,19100179 0,20230822 ! positive regulation of immune response GO:0050778 51 51 0,000 0,19443678 0,20582825 ! rRNA metabolic process GO:0016072 51 51 0,000 0,19443678 0,20571009 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,19443678 0,20559207 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,19443678 0,20547419 ! protein maturation GO:0051604 51 51 0,000 0,19443678 0,20535644 ! RNA localization GO:0006403 52 52 0,000 0,19785768 0,20884977 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,19785768 0,20873022 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,19785768 0,20861081 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,19785768 0,20849154 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,19785768 0,2083724 ! sodium ion transport GO:0006814 53 53 0,000 0,20126455 0,21183927 ! tRNA metabolic process GO:0006399 53 53 0,000 0,20126455 0,21171836 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,20126455 0,21159759 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,20126455 0,21147695 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,20126455 0,21135645 ! regulation of T cell activation GO:0050863 53 53 0,000 0,20126455 0,21123609 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,20465745 0,21467483 ! response to virus GO:0009615 54 54 0,000 0,20465745 0,21455272 ! hormone metabolic process GO:0042445 55 54 0,000 0,20465745 0,21443075 ! sulfur metabolic process GO:0006790 55 54 0,000 0,20465745 0,21430891 ! negative regulation of multicellular organismal process GO:0051241 55 54 0,000 0,20465745 0,21418721 ! nucleosome organization GO:0034728 55 55 0,000 0,20803643 0,21759997 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,20803643 0,21747654 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! regulation of cell adhesion GO:0030155 56 55 0,000 0,20803643 0,21735326 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,21140155 0,22074394 ! extracellular structure organization GO:0043062 56 56 0,000 0,21140155 0,22061895 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,21475287 0,22398955 ! innate immune response GO:0045087 58 58 0,000 0,21809042 0,227342 ! dephosphorylation GO:0016311 60 59 0,000 0,22141429 0,23067639 ! carboxylic acid transport GO:0046942 59 59 0,000 0,22141429 0,23054606 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,22141429 0,23041588 ! immune effector process GO:0002252 59 59 0,000 0,22141429 0,23028585 ! potassium ion transport GO:0006813 60 60 0,000 0,2247245 0,23359687 ! protein polymerization GO:0051258 65 60 0,000 0,2247245 0,2334652 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,22802113 0,23675658 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,22802113 0,23662328 ! lipid transport GO:0006869 62 62 0,000 0,23130422 0,23989514 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,23130422 0,23976022 GO:0060429|epithelium development, ! axonogenesis GO:0007409 66 62 0,000 0,23130422 0,23962545 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,23130422 0,23949083 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,23130422 0,23935636 ! regulation of lymphocyte activation GO:0051249 62 62 0,000 0,23130422 0,23922204 ! regulation of secretion GO:0051046 65 63 0,000 0,23457382 0,2424675 ! glucose metabolic process GO:0006006 63 63 0,000 0,23457382 0,24233159 ! regulation of response to external stimulus GO:0032101 65 64 0,000 0,23783 0,24555781 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,23783 0,24542032 ! anion transport GO:0006820 65 65 0,000 0,2410728 0,24862741 ! regulation of hormone levels GO:0010817 66 65 0,000 0,2410728 0,24848835 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,24430228 0,25167641 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! DNA packaging GO:0006323 66 66 0,000 0,24430228 0,25153581 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,24430228 0,25139537 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 0,000 0,24751849 0,25456282 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Golgi vesicle transport GO:0048193 67 67 0,000 0,24751849 0,25442084 ! muscle contraction GO:0006936 67 67 0,000 0,24751849 0,25427902 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,24751849 0,25413736 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,25072147 0,25728267 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,25072147 0,2571395 ! regulation of leukocyte activation GO:0002694 69 69 0,000 0,2539113 0,26026614 ! cell part morphogenesis GO:0032990 75 70 0,000 0,25708801 0,26337588 ! wound healing GO:0042060 74 70 0,000 0,25708801 0,26322956 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,25708801 0,2630834 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,26025166 0,26617303 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,26025166 0,2660254 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,26025166 0,26587794 ! regulation of cell activation GO:0050865 71 71 0,000 0,26025166 0,26573064 ! secretion by cell GO:0032940 75 72 0,000 0,2634023 0,26879869 ! muscle system process GO:0003012 72 72 0,000 0,2634023 0,26864993 ! sensory organ development GO:0007423 72 72 0,000 0,2634023 0,26850135 ! regulation of cytokine production GO:0001817 72 72 0,000 0,2634023 0,26835292 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,26966475 0,27458129 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,27277667 0,27759658 ! response to oxidative stress GO:0006979 76 75 0,000 0,27277667 0,27744338 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,27587579 0,28044075 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,27896215 0,28342185 ! microtubule-based movement GO:0007018 82 78 0,000 0,28203581 0,28638677 ! positive regulation of protein kinase cascade GO:0010740 79 78 0,000 0,28203581 0,28622907 ! metal ion homeostasis GO:0055065 78 78 0,000 0,28203581 0,28607154 ! regulation of immune response GO:0050776 78 78 0,000 0,28203581 0,28591419 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,28814522 0,29194702 ! neuron projection development GO:0031175 85 80 0,000 0,28814522 0,29178661 ! MAPKKK cascade GO:0000165 82 81 0,000 0,29118107 0,2946989 ! lipid catabolic process GO:0016042 82 81 0,000 0,29118107 0,29453716 ! ncRNA processing GO:0034470 83 83 0,000 0,29721531 0,30047604 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,30319994 0,30635828 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,30319994 0,30619041 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 0,000 0,30617378 0,30902424 ! hexose metabolic process GO:0019318 87 86 0,000 0,30617378 0,3088551 ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,31208473 0,3146456 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,31502194 0,31743326 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,32086008 0,32313941 ! DNA replication GO:0006260 91 91 0,000 0,32086008 0,32296293 ! visual perception GO:0007601 93 92 0,000 0,3237611 0,32570508 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,3237611 0,32552739 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,3237611 0,3253499 ! tissue morphogenesis GO:0048729 94 93 0,000 0,32665016 0,32807425 ! regulation of response to stress GO:0080134 97 94 0,000 0,3295273 0,33078367 ! epidermis development GO:0008544 94 94 0,000 0,3295273 0,3306036 ! cofactor metabolic process GO:0051186 95 94 0,000 0,3295273 0,33042373 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,34091762 0,34165914 ! blood circulation GO:0008015 99 98 0,000 0,34091762 0,34147346 GO:0003013|circulatory system process, ! regulation of system process GO:0044057 98 98 0,000 0,34091762 0,34128798 ! ectoderm development GO:0007398 99 99 0,000 0,34373587 0,34392248 ! response to other organism GO:0051707 101 100 0,000 0,34654248 0,34654248