pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6439-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 4,000 4,004E-10 9,633E-07 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 3,000 5,581E-09 6,714E-06 ! cell cycle arrest GO:0007050 213 100 6,000 3,345E-07 2,682E-04 ! steroid hormone receptor signaling pathway GO:0030518 129 63 5,000 3,825E-07 2,301E-04 ! androgen receptor signaling pathway GO:0030521 74 36 4,000 5,458E-07 2,627E-04 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 5,000 6,05E-07 2,426E-04 ! myoblast cell fate commitment GO:0048625 16 6 2,000 1,706E-06 5,863E-04 ! positive regulation of insulin secretion GO:0032024 15 8 2,000 4,745E-06 1,427E-03 ! catechol metabolic process GO:0009712 54 29 3,000 8,162E-06 2,182E-03 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! phenol metabolic process GO:0018958 55 30 3,000 9,386E-06 2,258E-03 ! positive regulation of peptide secretion GO:0002793 22 11 2,000 1,384E-05 3,028E-03 ! regulation of hormone metabolic process GO:0032350 26 12 2,000 1,84E-05 3,689E-03 ! aerobic respiration GO:0009060 55 36 3,000 1,976E-05 3,657E-03 ! catecholamine biosynthetic process GO:0042423 30 14 2,000 3,024E-05 5,198E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 3,768E-05 6,044E-03 ! ATP synthesis coupled electron transport GO:0042773 64 45 3,000 4,846E-05 7,287E-03 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! myoblast differentiation GO:0045445 45 17 2,000 5,595E-05 7,919E-03 ! positive regulation of hormone secretion GO:0046887 32 19 2,000 7,921E-05 0,01058791 ! respiratory electron transport chain GO:0022904 76 53 3,000 9,265E-05 0,01173219 ! response to UV GO:0009411 104 53 3,000 9,265E-05 0,01114558 ! pancreas development GO:0031016 35 20 2,000 9,289E-05 0,01064216 ! phosphatidylinositol metabolic process GO:0046488 36 21 2,000 1,08E-04 0,01181296 ! calcium-independent cell-cell adhesion GO:0016338 30 22 2,000 1,247E-04 0,01304092 ! regulation of insulin secretion GO:0050796 37 25 2,000 1,844E-04 0,01848377 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 1,948E-04 0,01874527 ! microvillus organization GO:0032528 7 5 1,000 1,948E-04 0,01802429 GO:0030033|microvillus assembly, ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 1,948E-04 0,01735673 ! meiotic chromosome segregation GO:0045132 7 5 1,000 1,948E-04 0,01673684 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 2,077E-04 0,01723599 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 3,000 2,311E-04 0,01853573 ! regulation of fibroblast proliferation GO:0048145 52 27 2,000 2,33E-04 0,01808057 ! fat cell differentiation GO:0045444 50 27 2,000 2,33E-04 0,01751555 ! negative regulation of ligase activity GO:0051352 112 68 3,000 2,447E-04 0,01784247 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 3,000 2,447E-04 0,01731769 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 3,000 2,589E-04 0,01779696 ! regulation of peptide secretion GO:0002791 47 29 2,000 2,891E-04 0,01932364 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 2,891E-04 0,01880138 ! male meiosis GO:0007140 7 6 1,000 2,913E-04 0,01844462 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 1,000 2,913E-04 0,01797168 ! establishment of spindle localization GO:0051293 12 6 1,000 2,913E-04 0,01752239 GO:0051653|spindle localization, ! negative regulation of neuroblast proliferation GO:0007406 21 6 1,000 2,913E-04 0,01709501 ! phosphoinositide metabolic process GO:0030384 128 72 3,000 3,049E-04 0,01746845 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 3,000 3,049E-04 0,0170622 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 3,000 3,049E-04 0,01667443 ! positive regulation of ligase activity GO:0051351 124 77 3,000 3,943E-04 0,02108151 ! regulation of helicase activity GO:0051095 15 7 1,000 4,066E-04 0,02126935 ! prostate gland development GO:0030850 13 7 1,000 4,066E-04 0,02081681 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 4,066E-04 0,02038313 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 4,066E-04 0,01996715 ! G1 DNA damage checkpoint GO:0031571 21 7 1,000 4,066E-04 0,0195678 ! B cell lineage commitment GO:0002326 21 7 1,000 4,066E-04 0,01918412 ! T cell lineage commitment GO:0002360 16 7 1,000 4,066E-04 0,0188152 ! response to tumor cell GO:0002347 13 7 1,000 4,066E-04 0,01846019 ! protein oligomerization GO:0051259 139 78 3,000 4,142E-04 0,01845416 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 3,000 4,348E-04 0,01901963 ! biogenic amine biosynthetic process GO:0042401 62 34 2,000 4,659E-04 0,02001562 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 5,406E-04 0,02281956 ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 1,000 5,406E-04 0,02242612 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 5,406E-04 0,02204601 ! ER overload response GO:0006983 12 8 1,000 5,406E-04 0,02167858 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 1,000 5,406E-04 0,02132319 ! regulation of ligase activity GO:0051340 142 84 3,000 5,489E-04 0,0212991 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 5,99E-04 0,02287782 ! oxidative phosphorylation GO:0006119 133 86 3,000 5,999E-04 0,02255361 ! carbohydrate homeostasis GO:0033500 53 38 2,000 6,483E-04 0,02399648 GO:0042593|glucose homeostasis, ! cellular respiration GO:0045333 135 88 3,000 6,543E-04 0,02385184 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 6,93E-04 0,02488762 ! neurotransmitter catabolic process GO:0042135 15 9 1,000 6,93E-04 0,02452163 ! regulation of hormone secretion GO:0046883 62 40 2,000 7,543E-04 0,02630349 ! mesenchymal cell development GO:0014031 87 40 2,000 7,543E-04 0,02592773 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 3,000 8,053E-04 0,02729037 GO:0010498|proteasomal protein catabolic process, ! biogenic amine metabolic process GO:0006576 155 94 3,000 8,382E-04 0,02801138 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 8,638E-04 0,02846935 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 8,638E-04 0,02808463 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 8,638E-04 0,02771017 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 1,000 8,638E-04 0,02734556 ! detection of calcium ion GO:0005513 23 10 1,000 8,638E-04 0,02699042 ! localization within membrane GO:0051668 20 10 1,000 8,638E-04 0,02664439 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 8,708E-04 0,02652178 ! skeletal muscle tissue development GO:0007519 186 99 3,000 1,017E-03 0,03059241 GO:0060538|skeletal muscle organ development, ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 1,053E-03 0,03126786 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 1,053E-03 0,03088654 ! regulation of intracellular pH GO:0051453 19 11 1,000 1,053E-03 0,03051441 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 1,066E-03 0,03053279 ! cell growth GO:0016049 84 45 2,000 1,066E-03 0,03017358 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 1,137E-03 0,03180015 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 1,137E-03 0,03143463 ! response to insulin stimulus GO:0032868 95 46 2,000 1,137E-03 0,03107742 ! protein homooligomerization GO:0051260 76 47 2,000 1,21E-03 0,03271715 ! regulation of B cell proliferation GO:0030888 20 12 1,000 1,26E-03 0,03367091 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 1,26E-03 0,0333009 ! histone acetylation GO:0016573 26 12 1,000 1,26E-03 0,03293893 ! peptidyl-lysine modification GO:0018205 21 12 1,000 1,26E-03 0,03258475 ! biogenic amine catabolic process GO:0042402 23 12 1,000 1,26E-03 0,03223811 ! positive regulation of cell cycle GO:0045787 89 48 2,000 1,287E-03 0,03258844 ! response to X-ray GO:0010165 25 13 1,000 1,484E-03 0,0371972 ! regulation of cellular pH GO:0030641 22 13 1,000 1,484E-03 0,03681372 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 1,484E-03 0,03643807 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 1,726E-03 0,04195917 ! palate development GO:0060021 31 14 1,000 1,726E-03 0,04153958 ! regulation of mRNA processing GO:0050684 24 14 1,000 1,726E-03 0,0411283 ! bone mineralization GO:0030282 17 14 1,000 1,726E-03 0,04072508 ! response to gamma radiation GO:0010332 28 14 1,000 1,726E-03 0,04032969 ! release of cytochrome c from mitochondria GO:0001836 30 14 1,000 1,726E-03 0,03994191 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 2,000 1,81E-03 0,04147037 ! regulation of protein catabolic process GO:0042176 116 55 2,000 1,908E-03 0,04330875 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 1,000 1,986E-03 0,0446643 ! regulation of exocytosis GO:0017157 22 15 1,000 1,986E-03 0,04425075 ! G1/S transition checkpoint GO:0031575 40 15 1,000 1,986E-03 0,04384478 ! dopamine metabolic process GO:0042417 35 15 1,000 1,986E-03 0,04344619 ! skeletal muscle fiber development GO:0048741 111 56 2,000 2,01E-03 0,04355781 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 2,114E-03 0,04542005 ! muscle fiber development GO:0048747 112 57 2,000 2,114E-03 0,0450181 ! regulation of intracellular transport GO:0032386 101 57 2,000 2,114E-03 0,04462321 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 2,263E-03 0,0473558 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 2,263E-03 0,04694756 ! cellular amino acid derivative catabolic process GO:0042219 29 16 1,000 2,263E-03 0,0465463 ! sphingolipid catabolic process GO:0030149 27 16 1,000 2,263E-03 0,04615184 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 1,000 2,263E-03 0,04576401 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 2,263E-03 0,04538264 ! positive regulation of secretion GO:0051047 95 59 2,000 2,334E-03 0,04640893 ! regulation of neurotransmitter levels GO:0001505 97 60 2,000 2,449E-03 0,04829475 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 2,558E-03 0,05003326 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 1,000 2,558E-03 0,04962976 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 2,558E-03 0,04923273 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 2,567E-03 0,04902163 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 2,869E-03 0,05435611 ! protein amino acid ADP-ribosylation GO:0006471 33 18 1,000 2,869E-03 0,05393145 ! lipid phosphorylation GO:0046834 35 19 1,000 3,197E-03 0,05963526 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 3,197E-03 0,05917652 ! negative regulation of cell growth GO:0030308 132 67 2,000 3,352E-03 0,06155627 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 1,000 3,542E-03 0,06456734 ! detection of chemical stimulus GO:0009593 37 20 1,000 3,542E-03 0,06408187 ! negative regulation of translation GO:0017148 29 20 1,000 3,542E-03 0,06360365 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 1,000 3,542E-03 0,06313251 ! protein amino acid acetylation GO:0006473 39 20 1,000 3,542E-03 0,0626683 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 3,542E-03 0,06221086 ! apoptotic mitochondrial changes GO:0008637 41 20 1,000 3,542E-03 0,06176006 ! cellular response to starvation GO:0009267 33 20 1,000 3,542E-03 0,06131574 ! negative regulation of cell size GO:0045792 134 69 2,000 3,642E-03 0,0625913 ! urogenital system development GO:0001655 137 69 2,000 3,642E-03 0,06214739 ! neurotransmitter metabolic process GO:0042133 34 21 1,000 3,904E-03 0,06614562 ! cell aging GO:0007569 44 21 1,000 3,904E-03 0,06568306 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 3,904E-03 0,06522693 ! reproductive structure development GO:0048608 113 71 2,000 3,947E-03 0,06550065 ! regulation of caspase activity GO:0043281 122 72 2,000 4,106E-03 0,06766188 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 4,282E-03 0,07008131 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 1,000 4,282E-03 0,06960778 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 1,000 4,282E-03 0,06914062 ! positive regulation of intracellular transport GO:0032388 37 22 1,000 4,282E-03 0,06867968 ! positive regulation of B cell activation GO:0050871 38 22 1,000 4,282E-03 0,06822485 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 4,282E-03 0,067776 ! protein stabilization GO:0050821 39 22 1,000 4,282E-03 0,06733302 ! meiosis GO:0007126 121 74 2,000 4,434E-03 0,06927476 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 2,000 4,434E-03 0,06882782 ! meiotic cell cycle GO:0051321 122 75 2,000 4,604E-03 0,07100692 ! sex determination GO:0007530 47 23 1,000 4,676E-03 0,07165826 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 1,000 4,676E-03 0,07120472 ! negative regulation of catabolic process GO:0009895 50 23 1,000 4,676E-03 0,0707569 ! regulation of catabolic process GO:0009894 161 76 2,000 4,778E-03 0,07184509 ! protein import into nucleus, translocation GO:0000060 46 24 1,000 5,086E-03 0,07600932 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 5,086E-03 0,07554013 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 5,086E-03 0,07507669 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 5,086E-03 0,07461891 ! protein tetramerization GO:0051262 52 24 1,000 5,086E-03 0,07416667 ! regulation of peptidase activity GO:0052547 134 79 2,000 5,323E-03 0,07714712 ! muscle cell differentiation GO:0042692 159 80 2,000 5,512E-03 0,07941688 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 5,512E-03 0,07894676 ! vasculogenesis GO:0001570 46 25 1,000 5,512E-03 0,07847962 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 5,512E-03 0,07801798 ! negative regulation of DNA replication GO:0008156 42 25 1,000 5,512E-03 0,07756173 ! response to starvation GO:0042594 42 25 1,000 5,512E-03 0,07711079 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 5,512E-03 0,07666506 ! negative regulation of cell development GO:0010721 73 25 1,000 5,512E-03 0,07622446 GO:0050768|negative regulation of neurogenesis, ! somitogenesis GO:0001756 43 25 1,000 5,512E-03 0,07578889 ! cellular response to nutrient levels GO:0031669 41 25 1,000 5,512E-03 0,07535827 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 5,904E-03 0,08024879 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 5,955E-03 0,08048684 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 5,955E-03 0,08003719 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of nuclear division GO:0051785 40 26 1,000 5,955E-03 0,07959254 GO:0045840|positive regulation of mitosis, ! negative regulation of growth GO:0045926 155 84 2,000 6,311E-03 0,08389229 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 6,412E-03 0,08476896 ! protein amino acid acylation GO:0043543 55 27 1,000 6,412E-03 0,08430574 ! mitochondrial membrane organization GO:0007006 57 27 1,000 6,412E-03 0,08384755 ! male gonad development GO:0008584 44 27 1,000 6,412E-03 0,08339432 ! base-excision repair GO:0006284 41 27 1,000 6,412E-03 0,08294597 ! regulation of chromosome organization GO:0033044 42 27 1,000 6,412E-03 0,08250241 ! amine biosynthetic process GO:0009309 138 86 2,000 6,735E-03 0,08619377 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 6,886E-03 0,08765388 ! regulation of protein transport GO:0051223 154 87 2,000 6,953E-03 0,08804899 GO:0070201|regulation of establishment of protein localization, ! regulation of pH GO:0006885 43 29 1,000 7,374E-03 0,09289114 ! tissue homeostasis GO:0001894 48 29 1,000 7,374E-03 0,09240733 GO:0048871|multicellular organismal homeostasis, ! ossification GO:0001503 188 90 2,000 7,633E-03 0,0951511 ! sex differentiation GO:0007548 145 90 2,000 7,633E-03 0,09466063 ! bone development GO:0060348 189 91 2,000 7,868E-03 0,0970735 ! neurotransmitter secretion GO:0007269 48 30 1,000 7,878E-03 0,09670652 ! regulation of B cell activation GO:0050864 50 30 1,000 7,878E-03 0,09621562 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 8,85E-03 0,10753638 ! spindle organization GO:0007051 46 32 1,000 8,931E-03 0,10797776 ! metanephros development GO:0001656 74 32 1,000 8,931E-03 0,10743788 ! response to ionizing radiation GO:0010212 65 32 1,000 8,931E-03 0,10690336 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 8,931E-03 0,10637413 ! positive regulation of catabolic process GO:0009896 64 32 1,000 8,931E-03 0,10585012 ! regulation of protein localization GO:0032880 176 97 2,000 9,366E-03 0,11046807 ! DNA damage checkpoint GO:0000077 71 33 1,000 9,48E-03 0,11125718 ! positive regulation of gene-specific transcription GO:0043193 65 33 1,000 9,48E-03 0,1107171 ! ceramide metabolic process GO:0006672 64 33 1,000 9,48E-03 0,11018223 ! negative regulation of protein transport GO:0051224 69 33 1,000 9,48E-03 0,10965251 ! interphase GO:0051325 213 98 2,000 9,631E-03 0,11087424 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 0,01062075 0,12168345 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,01062075 0,12110675 ! odontogenesis GO:0042476 66 35 1,000 0,01062075 0,12053549 ! negative regulation of hydrolase activity GO:0051346 62 35 1,000 0,01062075 0,1199696 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,01062075 0,11940899 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,01121301 0,12548145 ! sphingoid metabolic process GO:0046519 70 36 1,000 0,01121301 0,12490051 ! DNA integrity checkpoint GO:0031570 75 36 1,000 0,01121301 0,12432493 ! sister chromatid segregation GO:0000819 58 37 1,000 0,01181953 0,13044853 ! regulation of protein stability GO:0031647 73 37 1,000 0,01181953 0,12985288 ! meiosis I GO:0007127 65 37 1,000 0,01181953 0,12926264 ! monovalent inorganic cation homeostasis GO:0055067 58 37 1,000 0,01181953 0,12867774 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,01244015 0,13482434 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,01244015 0,13421974 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! learning GO:0007612 77 39 1,000 0,01307475 0,14043684 ! development of primary male sexual characteristics GO:0046546 66 39 1,000 0,01307475 0,13981268 ! segmentation GO:0035282 67 39 1,000 0,01307475 0,13919404 ! cytokinesis GO:0000910 72 40 1,000 0,01372319 0,14545377 ! T cell differentiation GO:0030217 81 41 1,000 0,01438535 0,15180325 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,01506107 0,1582399 GO:0090047|positive regulation of transcription regulator activity, ! neuron migration GO:0001764 79 42 1,000 0,01506107 0,1575519 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,01575024 0,16404795 ! regulation of epithelial cell proliferation GO:0050678 111 43 1,000 0,01575024 0,16334084 ! male sex differentiation GO:0046661 76 44 1,000 0,01645272 0,16989375 ! double-strand break repair GO:0006302 81 44 1,000 0,01645272 0,16916771 ! B cell differentiation GO:0030183 107 44 1,000 0,01645272 0,16844785 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 0,0178971 0,18245938 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,0178971 0,18168951 ! positive regulation of protein transport GO:0051222 72 46 1,000 0,0178971 0,18092611 ! response to calcium ion GO:0051592 81 47 1,000 0,01863873 0,18763513 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,01863873 0,18685332 ! mitochondrial transport GO:0006839 82 48 1,000 0,01939317 0,19360982 ! activation of caspase activity GO:0006919 84 48 1,000 0,01939317 0,19280977 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 0,01939317 0,19201632 ! histone modification GO:0016570 91 50 1,000 0,02093992 0,20648135 ! positive regulation of binding GO:0051099 78 51 1,000 0,02173199 0,21341698 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 1,000 0,02173199 0,21254943 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 0,02173199 0,21168891 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,02205094 0,21392966 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,02205094 0,21307051 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02205094 0,21221823 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,02205094 0,21137274 ! neuron fate determination GO:0048664 7 5 0,000 0,02205094 0,21053396 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02205094 0,20970181 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,02205094 0,20887621 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,02205094 0,20805709 ! polyol transport GO:0015791 12 5 0,000 0,02205094 0,20724436 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,02205094 0,20643796 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02205094 0,20563782 ! response to superoxide GO:0000303 10 5 0,000 0,02205094 0,20484385 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,02205094 0,20405599 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,02205094 0,20327416 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,02205094 0,20249831 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02205094 0,20172835 ! female meiosis GO:0007143 7 5 0,000 0,02205094 0,20096423 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02205094 0,20020587 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02205094 0,19945322 ! cobalt ion transport GO:0006824 11 5 0,000 0,02205094 0,1987062 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,02205094 0,19796476 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,02205094 0,19722884 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,02205094 0,19649836 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02205094 0,19577327 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02205094 0,19505352 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,02205094 0,19433904 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,02205094 0,19362977 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02205094 0,19292566 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,02205094 0,19222665 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,02205094 0,1915327 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02205094 0,19084373 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02205094 0,1901597 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02205094 0,18948056 ! negative chemotaxis GO:0050919 14 5 0,000 0,02205094 0,18880625 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02205094 0,18813673 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02205094 0,18747193 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,02205094 0,18681182 ! behavioral response to pain GO:0048266 9 5 0,000 0,02205094 0,18615634 ! clathrin coat assembly GO:0048268 14 5 0,000 0,02205094 0,18550544 ! Notch receptor processing GO:0007220 8 5 0,000 0,02205094 0,18485908 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02205094 0,18421721 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02205094 0,18357978 ! micturition GO:0060073 9 5 0,000 0,02205094 0,18294675 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02205094 0,18231806 ! copulation GO:0007620 9 5 0,000 0,02205094 0,18169369 ! glial cell fate commitment GO:0021781 13 5 0,000 0,02205094 0,18107357 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,02205094 0,18045768 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02205094 0,17984595 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02205094 0,17923837 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02205094 0,17863487 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,02205094 0,17803543 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02205094 0,17743999 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02205094 0,17684852 ! grooming behavior GO:0007625 6 5 0,000 0,02205094 0,17626099 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02205094 0,17567734 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,02205094 0,17509755 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02205094 0,17452157 ! response to protozoan GO:0001562 10 5 0,000 0,02205094 0,17394937 ! positive regulation of glycolysis GO:0045821 14 5 0,000 0,02205094 0,1733809 ! lymph vessel development GO:0001945 10 5 0,000 0,02205094 0,17281615 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,02205094 0,17225505 ! endochondral ossification GO:0001958 16 5 0,000 0,02205094 0,17169759 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02205094 0,17114373 ! parathyroid gland development GO:0060017 13 5 0,000 0,02205094 0,17059343 ! anagen GO:0042640 6 5 0,000 0,02205094 0,17004666 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02205094 0,16950338 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02205094 0,16896356 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,02205094 0,16842716 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,02205094 0,16789417 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,02205094 0,16736453 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,02205094 0,16683823 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,02205094 0,16631522 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,02205094 0,16579549 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,02205094 0,16527899 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02205094 0,1647657 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02205094 0,16425559 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02205094 0,16374863 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,02205094 0,16324479 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,02205094 0,16274404 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02205094 0,16224635 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,02205094 0,1617517 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,02205094 0,16126005 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02205094 0,16077138 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02205094 0,16028567 ! histidine catabolic process GO:0006548 6 5 0,000 0,02205094 0,15980288 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02205094 0,15932299 ! valine metabolic process GO:0006573 10 5 0,000 0,02205094 0,15884598 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,02205094 0,15837181 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02205094 0,15790047 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,02205094 0,15743192 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,02205094 0,15696614 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02205094 0,15650312 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,02205094 0,15604281 ! polyol catabolic process GO:0046174 7 5 0,000 0,02205094 0,15558521 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02205094 0,15513028 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02205094 0,15467801 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02205094 0,15422836 ! muscle cell migration GO:0014812 8 5 0,000 0,02205094 0,15378132 ! mitochondrial fission GO:0000266 8 5 0,000 0,02205094 0,15333687 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,02205094 0,15289498 ! mRNA transcription GO:0009299 9 5 0,000 0,02205094 0,15245562 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,02205094 0,15201879 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,02205094 0,15158445 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,02205094 0,15115258 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02205094 0,15072317 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02205094 0,15029619 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02205094 0,14987163 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02205094 0,14944946 ! response to food GO:0032094 6 5 0,000 0,02205094 0,14902965 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02205094 0,1486122 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02205094 0,14819709 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,02205094 0,14778428 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02205094 0,14737377 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,02205094 0,14696553 ! forebrain neuron development GO:0021884 13 5 0,000 0,02205094 0,14655955 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02205094 0,1461558 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,02205094 0,14575428 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02205094 0,14535495 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02205094 0,14495781 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02205094 0,14456282 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,02205094 0,14416999 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02205094 0,14377929 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,02205094 0,14339069 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,02205094 0,1430042 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02205094 0,14261978 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,02205094 0,14223742 ! basic amino acid transport GO:0015802 11 5 0,000 0,02205094 0,1418571 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02205094 0,14147882 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,02205094 0,14110254 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02205094 0,14072827 ! depyrimidination GO:0045008 10 5 0,000 0,02205094 0,14035597 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02205094 0,13998564 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02205094 0,13961725 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02205094 0,1392508 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,02205094 0,13888627 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,02205094 0,13852365 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02205094 0,13816291 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02205094 0,13780404 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02205094 0,13744704 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,02205094 0,13709188 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,02205094 0,13673855 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02205094 0,13638704 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02205094 0,13603732 ! response to arsenic GO:0046685 10 5 0,000 0,02205094 0,1356894 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,02205094 0,13534326 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02205094 0,13499887 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,02205094 0,13465624 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,02205094 0,13431533 ! response to cadmium ion GO:0046686 7 5 0,000 0,02205094 0,13397615 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,02205094 0,13363868 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,02205094 0,13330291 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02205094 0,13296881 ! decidualization GO:0046697 11 5 0,000 0,02205094 0,13263639 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,02205094 0,13230563 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,02205094 0,13197651 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02205094 0,13164902 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02205094 0,13132316 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,02205094 0,13099891 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02205094 0,13067625 ! neural tube patterning GO:0021532 7 5 0,000 0,02205094 0,13035518 ! embryonic cleavage GO:0040016 6 5 0,000 0,02205094 0,13003568 ! peroxisome fission GO:0016559 5 5 0,000 0,02205094 0,12971774 ! histone demethylation GO:0016577 10 5 0,000 0,02205094 0,12940136 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,02205094 0,12908651 ! mitotic recombination GO:0006312 9 5 0,000 0,02205094 0,1287732 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02205094 0,1284614 ! metaphase plate congression GO:0051310 7 5 0,000 0,02205094 0,1281511 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02205094 0,12784231 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02205094 0,12753499 ! enteric nervous system development GO:0048484 8 5 0,000 0,02205094 0,12722915 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,02205094 0,12692478 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,02205094 0,12662185 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,02205094 0,12632037 ! muscle cell proliferation GO:0033002 11 5 0,000 0,02205094 0,12602032 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02205094 0,1257217 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,02205094 0,12542448 ! plasminogen activation GO:0031639 5 5 0,000 0,02205094 0,12512867 ! B cell homeostasis GO:0001782 13 5 0,000 0,02205094 0,12483425 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,02205094 0,12454121 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02205094 0,12424955 ! metaphase GO:0051323 8 5 0,000 0,02205094 0,12395924 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,02205094 0,1236703 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02205094 0,12338269 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02205094 0,12309642 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02205094 0,12281147 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02205094 0,12252784 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02205094 0,12224552 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,02205094 0,1219645 ! response to redox state GO:0051775 5 5 0,000 0,02205094 0,12168476 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,02205094 0,12140631 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,02205094 0,12112912 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02205094 0,1208532 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,02205094 0,12057854 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02205094 0,12030512 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,02205094 0,12003293 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02205094 0,11976198 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,02205094 0,11949224 ! striatum development GO:0021756 9 5 0,000 0,02205094 0,11922372 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,02205094 0,11895641 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,02205094 0,11869028 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02205094 0,11842535 ! glial cell migration GO:0008347 11 5 0,000 0,02205094 0,1181616 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02205094 0,11789901 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,02205094 0,1176376 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02205094 0,11737734 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02205094 0,11711823 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02205094 0,11686026 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02205094 0,11660342 ! neuroprotection GO:0043526 6 5 0,000 0,02205094 0,11634771 ! neural plate development GO:0001840 8 5 0,000 0,02205094 0,11609312 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,02205094 0,11583964 ! regulation of sensory perception GO:0051931 7 5 0,000 0,02205094 0,11558727 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02205094 0,11533599 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02205094 0,11508581 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,02205094 0,1148367 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,02205094 0,11458868 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02205094 0,11434172 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02205094 0,11409582 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02205094 0,11385098 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02205094 0,11360719 ! spindle assembly GO:0051225 6 5 0,000 0,02205094 0,11336444 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,02205094 0,11312272 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02205094 0,11288204 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02205094 0,11264237 ! drug metabolic process GO:0017144 6 5 0,000 0,02205094 0,11240372 ! stem cell division GO:0017145 11 5 0,000 0,02205094 0,11216608 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,02205094 0,11192944 ! organ regeneration GO:0031100 7 5 0,000 0,02205094 0,1116938 ! carnitine metabolic process GO:0009437 7 5 0,000 0,02205094 0,11145915 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,02205094 0,11122549 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02205094 0,1109928 ! covalent chromatin modification GO:0016569 101 52 1,000 0,02253635 0,11319927 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,02335288 0,1170563 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,02418146 0,12095756 GO:0010863|positive regulation of phospholipase C activity, ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 1,000 0,02418146 0,12070661 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,02502196 0,12464358 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,02502196 0,12438605 ! aging GO:0007568 103 55 1,000 0,02502196 0,12412958 ! RNA elongation GO:0006354 79 55 1,000 0,02502196 0,12387417 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,02502196 0,12361981 ! nucleotide-excision repair GO:0006289 83 56 1,000 0,02587428 0,12756867 ! regulation of DNA replication GO:0006275 101 56 1,000 0,02587428 0,12730779 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,02587428 0,12704798 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02640286 0,12937941 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02640286 0,12911644 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,02640286 0,12885454 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02640286 0,1285937 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02640286 0,12833392 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,02640286 0,12807518 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,02640286 0,12781748 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02640286 0,12756082 ! sleep GO:0030431 13 6 0,000 0,02640286 0,12730519 ! response to oxygen radical GO:0000305 11 6 0,000 0,02640286 0,12705058 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,02640286 0,12679698 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,02640286 0,1265444 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,02640286 0,12629282 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02640286 0,12604224 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02640286 0,12579265 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,02640286 0,12554405 ! forebrain regionalization GO:0021871 8 6 0,000 0,02640286 0,12529643 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02640286 0,12504978 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02640286 0,1248041 ! response to zinc ion GO:0010043 9 6 0,000 0,02640286 0,12455939 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02640286 0,12431563 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,02640286 0,12407283 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02640286 0,12383097 ! malate metabolic process GO:0006108 11 6 0,000 0,02640286 0,12359006 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,02640286 0,12335008 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,02640286 0,12311103 ! protein refolding GO:0042026 15 6 0,000 0,02640286 0,1228729 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02640286 0,12263569 ! opsonization GO:0008228 8 6 0,000 0,02640286 0,1223994 ! mating behavior GO:0007617 7 6 0,000 0,02640286 0,12216402 ! neuron remodeling GO:0016322 15 6 0,000 0,02640286 0,12192954 ! erythrocyte maturation GO:0043249 7 6 0,000 0,02640286 0,12169596 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,02640286 0,12146327 ! equilibrioception GO:0050957 14 6 0,000 0,02640286 0,12123147 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,02640286 0,12100055 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,02640286 0,12077051 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02640286 0,12054135 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,02640286 0,12031305 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02640286 0,12008561 ! response to interferon-gamma GO:0034341 15 6 0,000 0,02640286 0,11985904 ! toxin metabolic process GO:0009404 11 6 0,000 0,02640286 0,11963331 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02640286 0,11940844 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02640286 0,11918441 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,02640286 0,11896122 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,02640286 0,11873886 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,02640286 0,11851733 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,02640286 0,11829663 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02640286 0,11807675 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,02640286 0,11785768 ! thymic T cell selection GO:0045061 12 6 0,000 0,02640286 0,11763942 ! protein lipoylation GO:0009249 10 6 0,000 0,02640286 0,11742198 ! cysteine metabolic process GO:0006534 10 6 0,000 0,02640286 0,11720533 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02640286 0,11698948 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02640286 0,11677443 ! glutamate catabolic process GO:0006538 10 6 0,000 0,02640286 0,11656016 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,02640286 0,11634668 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02640286 0,11613398 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,02640286 0,11592206 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,02640286 0,11571091 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02640286 0,11550053 ! hyperosmotic response GO:0006972 9 6 0,000 0,02640286 0,11529091 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,02640286 0,11508205 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,02640286 0,11487394 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02640286 0,11466659 ! urea metabolic process GO:0019627 7 6 0,000 0,02640286 0,11445998 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02640286 0,11425412 ! neutrophil activation GO:0042119 8 6 0,000 0,02640286 0,11404899 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02640286 0,1138446 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,02640286 0,11364095 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02640286 0,11343802 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02640286 0,11323581 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02640286 0,11303432 ! neuron apoptosis GO:0051402 9 6 0,000 0,02640286 0,11283355 ! nucleoside salvage GO:0043174 9 6 0,000 0,02640286 0,11263349 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,02640286 0,11243414 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02640286 0,11223549 ! T cell mediated immunity GO:0002456 16 6 0,000 0,02640286 0,11203755 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02640286 0,1118403 GO:0010543|regulation of platelet activation, ! male sex determination GO:0030238 15 6 0,000 0,02640286 0,11164374 ! carnitine transport GO:0015879 10 6 0,000 0,02640286 0,11144788 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,02640286 0,1112527 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02640286 0,1110582 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,02640286 0,11086438 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,02640286 0,11067124 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,02640286 0,11047876 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02640286 0,11028696 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,02640286 0,11009582 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,02640286 0,10990534 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,02640286 0,10971552 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,02640286 0,10952636 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02640286 0,10933785 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,02640286 0,10914998 ! neural nucleus development GO:0048857 14 6 0,000 0,02640286 0,10896276 ! response to UV-C GO:0010225 11 6 0,000 0,02640286 0,10877618 ! astrocyte development GO:0014002 15 6 0,000 0,02640286 0,10859024 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,02640286 0,10840493 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02640286 0,10822025 ! interaction with symbiont GO:0051702 13 6 0,000 0,02640286 0,10803621 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02640286 0,10785278 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02640286 0,10766998 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,02640286 0,1074878 ! response to copper ion GO:0046688 10 6 0,000 0,02640286 0,10730623 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,02640286 0,10712528 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,02640286 0,10694493 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02640286 0,10676519 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02640286 0,10658606 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02640286 0,10640752 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,02640286 0,10622958 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02640286 0,10605224 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,02640286 0,10587548 ! hair follicle maturation GO:0048820 7 6 0,000 0,02640286 0,10569932 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02640286 0,10552374 ! Schwann cell development GO:0014044 15 6 0,000 0,02640286 0,10534874 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,02640286 0,10517432 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02640286 0,10500048 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,02640286 0,10482721 ! subpallium development GO:0021544 10 6 0,000 0,02640286 0,10465451 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,02640286 0,10448238 ! histone ubiquitination GO:0016574 8 6 0,000 0,02640286 0,10431082 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,02640286 0,10413982 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02640286 0,10396938 ! G2 phase GO:0051319 16 6 0,000 0,02640286 0,10379949 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,02640286 0,10363016 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02640286 0,10346138 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,02640286 0,10329315 ! membrane to membrane docking GO:0022614 14 6 0,000 0,02640286 0,10312547 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02640286 0,10295833 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,02640286 0,10279173 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02640286 0,10262567 ! receptor internalization GO:0031623 10 6 0,000 0,02640286 0,10246014 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,02640286 0,10229515 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,02640286 0,10213069 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02640286 0,10196676 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,02640286 0,10180335 ! protein deubiquitination GO:0016579 14 6 0,000 0,02640286 0,10164046 ! protein destabilization GO:0031648 9 6 0,000 0,02640286 0,1014781 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02640286 0,10131625 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,02640286 0,10115492 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02640286 0,1009941 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,02640286 0,10083379 ! progesterone metabolic process GO:0042448 10 6 0,000 0,02640286 0,10067399 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,02640286 0,1005147 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,02640286 0,10035591 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,02640286 0,10019762 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,02640286 0,10003983 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02640286 0,09988253 ! determination of adult lifespan GO:0008340 15 6 0,000 0,02640286 0,09972573 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,02640286 0,09956942 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,02640286 0,0994136 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02640286 0,09925826 ! catecholamine transport GO:0051937 9 6 0,000 0,02640286 0,09910341 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,02640286 0,09894905 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02640286 0,09879516 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02640286 0,09864175 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,02640286 0,09848882 ! maternal placenta development GO:0001893 12 6 0,000 0,02640286 0,09833636 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,02640286 0,09818437 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02640286 0,09803285 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,02640286 0,0978818 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,02640286 0,09773121 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02640286 0,09758109 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,02640286 0,09743142 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,02640286 0,09728222 ! positive regulation of cell migration GO:0030335 126 57 1,000 0,02673828 0,09836742 ! lipid modification GO:0030258 97 57 1,000 0,02673828 0,09821724 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,02673828 0,09806752 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,02761384 0,10112466 ! establishment of organelle localization GO:0051656 109 59 1,000 0,02850085 0,10421437 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,0293992 0,10733608 ! camera-type eye development GO:0043010 116 60 1,000 0,0293992 0,10717345 ! protein amino acid autophosphorylation GO:0046777 141 60 1,000 0,0293992 0,10701131 ! kidney development GO:0001822 122 60 1,000 0,0293992 0,10684966 ! sphingolipid metabolic process GO:0006665 107 61 1,000 0,03030876 0,10998925 ! tRNA transcription GO:0009304 14 7 0,000 0,03073557 0,11137014 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,03073557 0,11120266 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,03073557 0,11103569 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03073557 0,11086922 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,03073557 0,11070325 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,03073557 0,11053778 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03073557 0,11037279 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,03073557 0,1102083 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03073557 0,1100443 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,03073557 0,10988079 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03073557 0,10971776 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03073557 0,10955522 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,03073557 0,10939315 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03073557 0,10923157 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,03073557 0,10907046 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,03073557 0,10890983 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,03073557 0,10874966 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,03073557 0,10858997 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03073557 0,10843075 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,03073557 0,10827199 ! glycolipid transport GO:0046836 10 7 0,000 0,03073557 0,1081137 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03073557 0,10795587 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,03073557 0,1077985 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03073557 0,10764159 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,03073557 0,10748513 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03073557 0,10732913 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,03073557 0,10717358 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,03073557 0,10701848 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,03073557 0,10686383 ! mRNA stabilization GO:0048255 18 7 0,000 0,03073557 0,10670963 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,03073557 0,10655587 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,03073557 0,10640255 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,03073557 0,10624967 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,03073557 0,10609723 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03073557 0,10594523 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03073557 0,10579367 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03073557 0,10564253 ! lipoprotein transport GO:0042953 14 7 0,000 0,03073557 0,10549183 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03073557 0,10534156 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03073557 0,10519171 ! rhythmic behavior GO:0007622 15 7 0,000 0,03073557 0,10504229 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,03073557 0,10489329 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,03073557 0,10474472 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,03073557 0,10459657 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03073557 0,10444883 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,03073557 0,10430151 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03073557 0,10415461 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,03073557 0,10400812 ! mechanosensory behavior GO:0007638 14 7 0,000 0,03073557 0,10386204 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,03073557 0,10371637 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03073557 0,10357111 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,03073557 0,10342625 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03073557 0,1032818 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03073557 0,10313776 ! spinal cord patterning GO:0021511 13 7 0,000 0,03073557 0,10299411 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,03073557 0,10285087 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03073557 0,10270802 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,03073557 0,10256556 ! adrenal gland development GO:0030325 17 7 0,000 0,03073557 0,10242351 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,03073557 0,10228184 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,03073557 0,10214057 ! ovulation GO:0030728 9 7 0,000 0,03073557 0,10199969 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,03073557 0,10185919 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,03073557 0,10171908 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,03073557 0,10157936 ! microtubule nucleation GO:0007020 20 7 0,000 0,03073557 0,10144002 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03073557 0,10130106 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03073557 0,10116248 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,03073557 0,10102428 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,03073557 0,10088646 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,03073557 0,10074901 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03073557 0,10061193 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03073557 0,10047523 ! galactose metabolic process GO:0006012 13 7 0,000 0,03073557 0,1003389 ! vesicle fusion GO:0006906 17 7 0,000 0,03073557 0,10020294 ! response to dietary excess GO:0002021 8 7 0,000 0,03073557 0,10006735 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03073557 0,09993212 ! intracellular pH reduction GO:0051452 11 7 0,000 0,03073557 0,09979726 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03073557 0,09966277 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,03073557 0,09952863 ! organ growth GO:0035265 15 7 0,000 0,03073557 0,09939485 ! purine salvage GO:0043101 10 7 0,000 0,03073557 0,09926144 ! nucleoside transport GO:0015858 8 7 0,000 0,03073557 0,09912838 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,03073557 0,09899568 ! parturition GO:0007567 14 7 0,000 0,03073557 0,09886333 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,03073557 0,09873134 ! rRNA modification GO:0000154 14 7 0,000 0,03073557 0,0985997 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,03073557 0,0984684 ! spindle checkpoint GO:0031577 15 7 0,000 0,03073557 0,09833746 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,03073557 0,09820687 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,03073557 0,09807662 ! macrophage differentiation GO:0030225 11 7 0,000 0,03073557 0,09794672 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03073557 0,09781716 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03073557 0,09768794 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,03073557 0,09755907 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,03073557 0,09743053 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03073557 0,09730233 ! fibrinolysis GO:0042730 10 7 0,000 0,03073557 0,09717447 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,03073557 0,09704694 ! eating behavior GO:0042755 7 7 0,000 0,03073557 0,09691975 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03073557 0,0967929 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,03073557 0,09666637 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,03073557 0,09654017 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03073557 0,09641431 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,03073557 0,09628877 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03073557 0,09616355 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,03073557 0,09603866 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,03073557 0,0959141 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,03073557 0,09578986 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,03073557 0,09566594 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03073557 0,09554234 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,03073557 0,09541906 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03073557 0,0952961 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03073557 0,09517345 ! regulation of meiosis GO:0040020 12 7 0,000 0,03073557 0,09505112 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,03073557 0,0949291 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,03073557 0,0948074 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03073557 0,09468601 ! oxygen homeostasis GO:0032364 12 7 0,000 0,03073557 0,09456493 ! transcription termination GO:0006353 13 7 0,000 0,03073557 0,09444415 ! regulation of respiratory burst GO:0060263 11 7 0,000 0,03073557 0,09432369 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03073557 0,09420353 ! anaphase GO:0051322 17 7 0,000 0,03073557 0,09408368 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,03073557 0,09396413 ! axonal fasciculation GO:0007413 18 7 0,000 0,03073557 0,09384489 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,03073557 0,09372595 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,03073557 0,09360731 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,03073557 0,09348897 ! diuresis GO:0030146 12 7 0,000 0,03073557 0,09337092 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03073557 0,09325318 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03073557 0,09313573 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03073557 0,09301858 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,03073557 0,09290172 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,03073557 0,09278516 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03073557 0,09266889 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03073557 0,09255291 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03073557 0,09243722 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03073557 0,09232181 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,03073557 0,0922067 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03073557 0,09209187 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,03073557 0,09197733 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03073557 0,09186307 ! lymph node development GO:0048535 10 7 0,000 0,03073557 0,0917491 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,03073557 0,09163541 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03073557 0,091522 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,03073557 0,09140887 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,03073557 0,09129601 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,03073557 0,09118344 ! adult feeding behavior GO:0008343 9 7 0,000 0,03073557 0,09107115 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,03073557 0,09095913 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,03073557 0,09084739 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03073557 0,09073592 ! muscle adaptation GO:0043500 14 7 0,000 0,03073557 0,09062472 ! embryonic heart tube development GO:0035050 10 7 0,000 0,03073557 0,0905138 ! retina homeostasis GO:0001895 12 7 0,000 0,03073557 0,09040314 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,03073557 0,09029276 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,03073557 0,09018265 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,03073557 0,0900728 ! protein prenylation GO:0018342 18 7 0,000 0,03073557 0,08996323 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,03073557 0,08985392 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,03073557 0,08974487 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03073557 0,08963609 ! gonad development GO:0008406 98 62 1,000 0,03122942 0,09096607 ! regulation of mitosis GO:0007088 105 63 1,000 0,03216105 0,0935665 GO:0051783|regulation of nuclear division, ! positive regulation of cell motion GO:0051272 146 64 1,000 0,03310356 0,09619224 ! germ cell development GO:0007281 118 65 1,000 0,03405683 0,09884285 ! cell projection assembly GO:0030031 120 66 1,000 0,03502073 0,10151793 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,03504913 0,10147799 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,03504913 0,10135602 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,03504913 0,10123434 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,03504913 0,10111296 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03504913 0,10099187 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03504913 0,10087106 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,03504913 0,10075055 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,03504913 0,10063032 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,03504913 0,10051038 ! meiotic prophase I GO:0007128 13 8 0,000 0,03504913 0,10039072 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03504913 0,10027135 ! oligopeptide transport GO:0006857 15 8 0,000 0,03504913 0,10015227 ! UTP metabolic process GO:0046051 8 8 0,000 0,03504913 0,10003346 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,03504913 0,09991494 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,03504913 0,0997967 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,03504913 0,09967873 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03504913 0,09956105 ! succinate metabolic process GO:0006105 14 8 0,000 0,03504913 0,09944364 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,03504913 0,09932651 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03504913 0,09920966 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,03504913 0,09909308 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,03504913 0,09897677 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,03504913 0,09886074 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03504913 0,09874498 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03504913 0,09862948 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,03504913 0,09851426 ! reflex GO:0060004 16 8 0,000 0,03504913 0,09839931 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,03504913 0,09828463 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,03504913 0,09817021 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03504913 0,09805606 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,03504913 0,09794217 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,03504913 0,09782855 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,03504913 0,09771519 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03504913 0,09760209 ! pigment granule organization GO:0048753 16 8 0,000 0,03504913 0,09748926 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,03504913 0,09737668 ! astrocyte differentiation GO:0048708 18 8 0,000 0,03504913 0,09726437 ! histidine metabolic process GO:0006547 16 8 0,000 0,03504913 0,09715231 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03504913 0,09704052 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,03504913 0,09692898 ! glycine catabolic process GO:0006546 13 8 0,000 0,03504913 0,09681769 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,03504913 0,09670666 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,03504913 0,09659589 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,03504913 0,09648536 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,03504913 0,0963751 ! melanin metabolic process GO:0006582 15 8 0,000 0,03504913 0,09626508 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,03504913 0,09615531 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,03504913 0,0960458 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,03504913 0,09593653 ! macrophage activation GO:0042116 12 8 0,000 0,03504913 0,09582751 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03504913 0,09571874 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,03504913 0,09561021 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03504913 0,09550194 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,03504913 0,0953939 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,03504913 0,09528611 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,03504913 0,09517857 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,03504913 0,09507126 ! osteoblast development GO:0002076 16 8 0,000 0,03504913 0,0949642 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,03504913 0,09485738 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,03504913 0,0947508 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,03504913 0,09464445 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,03504913 0,09453835 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,03504913 0,09443248 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03504913 0,09432686 ! response to UV-B GO:0010224 16 8 0,000 0,03504913 0,09422146 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,03504913 0,0941163 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03504913 0,09401138 ! intermediate filament organization GO:0045109 12 8 0,000 0,03504913 0,09390669 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,03504913 0,09380223 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,03504913 0,09369801 ! cellular extravasation GO:0045123 12 8 0,000 0,03504913 0,09359402 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,03504913 0,09349025 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,03504913 0,09338672 ! response to antibiotic GO:0046677 11 8 0,000 0,03504913 0,09328342 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,03504913 0,09318034 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,03504913 0,09307749 ! DNA topological change GO:0006265 12 8 0,000 0,03504913 0,09297487 ! response to tropane GO:0014073 15 8 0,000 0,03504913 0,09287248 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,03504913 0,09277031 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 0,000 0,03504913 0,09266836 ! melanosome transport GO:0032402 13 8 0,000 0,03504913 0,09256664 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,03504913 0,09246514 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03504913 0,09236387 ! mast cell activation GO:0045576 14 8 0,000 0,03504913 0,09226281 ! multicellular organismal aging GO:0010259 18 8 0,000 0,03504913 0,09216198 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,03504913 0,09206136 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,03504913 0,09196097 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,03504913 0,09186079 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03504913 0,09176084 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03504913 0,0916611 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,03504913 0,09156157 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,03504913 0,09146227 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03504913 0,09136317 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,03504913 0,0912643 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,03504913 0,09116563 ! intracellular lipid transport GO:0032365 13 8 0,000 0,03504913 0,09106718 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03504913 0,09096894 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,03504913 0,09087091 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,03504913 0,0907731 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,03504913 0,09067549 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03504913 0,0905781 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,03504913 0,09048091 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,03504913 0,09038393 ! hormone catabolic process GO:0042447 17 8 0,000 0,03504913 0,09028716 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03504913 0,0901906 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,03504913 0,09009424 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,03504913 0,08999809 ! ATP catabolic process GO:0006200 11 8 0,000 0,03504913 0,08990214 ! blastocyst growth GO:0001832 19 8 0,000 0,03504913 0,0898064 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03504913 0,08971086 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03504913 0,08961552 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,03504913 0,08952039 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03504913 0,08942546 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,03504913 0,08933073 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,03504913 0,0892362 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,03504913 0,08914187 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,03504913 0,08904774 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,03504913 0,08895381 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,03504913 0,08886007 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,03504913 0,08876654 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03504913 0,0886732 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,03504913 0,08858005 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03504913 0,0884871 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,03504913 0,08839435 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,03504913 0,08830179 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,03504913 0,08820942 ! negative regulation of protein kinase activity GO:0006469 130 67 1,000 0,03599517 0,09049569 ! lung development GO:0030324 144 67 1,000 0,03599517 0,09040123 ! chromosome segregation GO:0007059 113 67 1,000 0,03599517 0,09030696 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,03599517 0,09021289 ! negative regulation of kinase activity GO:0033673 131 68 1,000 0,03698002 0,09258474 ! membrane lipid metabolic process GO:0006643 117 68 1,000 0,03698002 0,0924885 ! regulation of lipase activity GO:0060191 130 68 1,000 0,03698002 0,09239246 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,03797519 0,09478039 ! respiratory tube development GO:0030323 150 70 1,000 0,03898055 0,09718881 ! regulation of developmental growth GO:0048638 15 9 0,000 0,03934364 0,09799255 ! axon extension GO:0048675 15 9 0,000 0,03934364 0,09789121 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,03934364 0,09779008 ! positive regulation of glucose metabolic process GO:0010907 18 9 0,000 0,03934364 0,09768917 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,03934364 0,09758845 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,03934364 0,09748795 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,03934364 0,09738766 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,03934364 0,09728757 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,03934364 0,09718768 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,03934364 0,097088 ! phosphate transport GO:0006817 19 9 0,000 0,03934364 0,09698853 ! reproductive behavior GO:0019098 19 9 0,000 0,03934364 0,09688925 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,03934364 0,09679019 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,03934364 0,09669132 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03934364 0,09659265 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,03934364 0,09649419 ! GTP metabolic process GO:0046039 9 9 0,000 0,03934364 0,09639593 ! RNA methylation GO:0001510 15 9 0,000 0,03934364 0,09629786 ! elastic fiber assembly GO:0048251 15 9 0,000 0,03934364 0,0962 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,03934364 0,09610234 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,03934364 0,09600487 ! artery development GO:0060840 24 9 0,000 0,03934364 0,0959076 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,03934364 0,09581053 ! regulation of glycolysis GO:0006110 21 9 0,000 0,03934364 0,09571365 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,03934364 0,09561697 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,03934364 0,09552049 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,03934364 0,09542419 ! chemosensory behavior GO:0007635 20 9 0,000 0,03934364 0,0953281 ! microtubule bundle formation GO:0001578 21 9 0,000 0,03934364 0,09523219 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,03934364 0,09513648 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,03934364 0,09504096 ! leukocyte degranulation GO:0043299 16 9 0,000 0,03934364 0,09494564 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,03934364 0,0948505 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,03934364 0,09475556 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,03934364 0,0946608 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,03934364 0,09456623 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,03934364 0,09447186 ! protein targeting to ER GO:0045047 22 9 0,000 0,03934364 0,09437767 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,03934364 0,09428367 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,03934364 0,09418985 ! T cell selection GO:0045058 23 9 0,000 0,03934364 0,09409622 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,03934364 0,09400278 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03934364 0,09390952 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,03934364 0,09381645 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,03934364 0,09372357 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03934364 0,09363086 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,03934364 0,09353834 ! mannose metabolic process GO:0006013 13 9 0,000 0,03934364 0,093446 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,03934364 0,09335385 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,03934364 0,09326187 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,03934364 0,09317008 ! receptor clustering GO:0043113 18 9 0,000 0,03934364 0,09307847 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,03934364 0,09298703 ! ruffle organization GO:0031529 15 9 0,000 0,03934364 0,09289578 ! retinol metabolic process GO:0042572 18 9 0,000 0,03934364 0,09280471 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,03934364 0,09271381 ! behavioral fear response GO:0001662 22 9 0,000 0,03934364 0,09262309 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,03934364 0,09253255 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,03934364 0,09244219 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,03934364 0,092352 GO:0030204|chondroitin sulfate metabolic process, ! motor axon guidance GO:0008045 16 9 0,000 0,03934364 0,09226199 ! protein heterooligomerization GO:0051291 16 9 0,000 0,03934364 0,09217215 ! oligodendrocyte development GO:0014003 10 9 0,000 0,03934364 0,09208249 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,03934364 0,091993 ! segment specification GO:0007379 13 9 0,000 0,03934364 0,09190369 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,03934364 0,09181455 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,03934364 0,09172558 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,03934364 0,09163679 ! response to amine stimulus GO:0014075 13 9 0,000 0,03934364 0,09154816 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,03934364 0,09145971 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,03934364 0,09137143 ! erythrocyte development GO:0048821 15 9 0,000 0,03934364 0,09128332 ! gas homeostasis GO:0033483 16 9 0,000 0,03934364 0,09119538 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,03934364 0,0911076 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,03934364 0,09102 ! renal water homeostasis GO:0003091 14 9 0,000 0,03934364 0,09093257 ! postreplication repair GO:0006301 22 9 0,000 0,03934364 0,0908453 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,03934364 0,0907582 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,03934364 0,09067127 ! icosanoid secretion GO:0032309 15 9 0,000 0,03934364 0,0905845 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,03934364 0,0904979 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,03934364 0,09041146 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,03934364 0,09032519 ! regulation of cell division GO:0051302 15 9 0,000 0,03934364 0,09023909 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,03934364 0,09015314 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,03934364 0,09006737 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,03934364 0,08998175 ! sterol catabolic process GO:0016127 11 9 0,000 0,03934364 0,0898963 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,03934364 0,08981101 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,03934364 0,08972588 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,03934364 0,08964091 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,03934364 0,0895561 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,03934364 0,08947146 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,03934364 0,08938697 ! musculoskeletal movement GO:0050881 14 9 0,000 0,03934364 0,08930264 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,03934364 0,08921847 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,03934364 0,08913446 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,03934364 0,08905061 ! purine base metabolic process GO:0006144 21 9 0,000 0,03934364 0,08896692 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,03934364 0,08888338 ! pigment granule transport GO:0051904 17 9 0,000 0,03934364 0,0888 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,03934364 0,08871678 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,03934364 0,08863371 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,03934364 0,0885508 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,03934364 0,08846804 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03934364 0,08838544 ! mitochondrion localization GO:0051646 15 9 0,000 0,03934364 0,08830299 ! amine catabolic process GO:0009310 117 71 1,000 0,039996 0,08968348 ! B cell activation GO:0042113 160 71 1,000 0,039996 0,08959998 ! negative regulation of transferase activity GO:0051348 140 72 1,000 0,04102143 0,09181169 ! respiratory system development GO:0060541 153 72 1,000 0,04102143 0,09172636 ! learning or memory GO:0007611 147 73 1,000 0,04205674 0,09395406 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,04310182 0,09619941 GO:0090046|regulation of transcription regulator activity, ! neurotransmitter transport GO:0006836 123 74 1,000 0,04310182 0,09611026 ! eye development GO:0001654 143 74 1,000 0,04310182 0,09602127 ! organelle localization GO:0051640 136 74 1,000 0,04310182 0,09593244 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,04361918 0,09699422 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04361918 0,09690466 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,04361918 0,09681527 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04361918 0,09672604 ! synapsis GO:0007129 13 10 0,000 0,04361918 0,09663697 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,04361918 0,09654807 ! N-glycan processing GO:0006491 20 10 0,000 0,04361918 0,09645933 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,04361918 0,09637075 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,04361918 0,09628234 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,04361918 0,09619409 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,04361918 0,096106 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,04361918 0,09601807 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,04361918 0,0959303 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,04361918 0,09584269 ! androgen metabolic process GO:0008209 17 10 0,000 0,04361918 0,09575525 ! phospholipid efflux GO:0033700 16 10 0,000 0,04361918 0,09566796 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04361918 0,09558083 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,04361918 0,09549386 ! lung alveolus development GO:0048286 26 10 0,000 0,04361918 0,09540705 ! pathogenesis GO:0009405 13 10 0,000 0,04361918 0,09532039 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04361918 0,09523389 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,04361918 0,09514755 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,04361918 0,09506137 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,04361918 0,09497534 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,04361918 0,09488947 ! endoderm development GO:0007492 16 10 0,000 0,04361918 0,09480375 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,04361918 0,09471819 ! arginine catabolic process GO:0006527 13 10 0,000 0,04361918 0,09463278 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04361918 0,09454752 ! proline metabolic process GO:0006560 13 10 0,000 0,04361918 0,09446242 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04361918 0,09437747 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,04361918 0,09429268 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,04361918 0,09420803 ! V(D)J recombination GO:0033151 28 10 0,000 0,04361918 0,09412354 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,04361918 0,0940392 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,04361918 0,09395501 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,04361918 0,09387097 ! B cell proliferation GO:0042100 18 10 0,000 0,04361918 0,09378709 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,04361918 0,09370335 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,04361918 0,09361976 ! multicellular organism growth GO:0035264 18 10 0,000 0,04361918 0,09353632 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,04361918 0,09345303 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,04361918 0,09336988 ! epithelial cell development GO:0002064 20 10 0,000 0,04361918 0,09328689 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,04361918 0,09320404 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04361918 0,09312134 ! macroautophagy GO:0016236 17 10 0,000 0,04361918 0,09303879 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,04361918 0,09295638 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,04361918 0,09287411 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,04361918 0,092792 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,04361918 0,09271003 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04361918 0,0926282 ! regulation of bone resorption GO:0045124 25 10 0,000 0,04361918 0,09254652 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04361918 0,09246498 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04361918 0,09238358 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,04361918 0,09230233 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,04361918 0,09222122 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,04361918 0,09214025 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,04361918 0,09205943 ! blastoderm segmentation GO:0007350 18 10 0,000 0,04361918 0,09197875 ! response to dsRNA GO:0043331 20 10 0,000 0,04361918 0,0918982 ! DNA ligation GO:0006266 19 10 0,000 0,04361918 0,0918178 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,04361918 0,09173754 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04361918 0,09165742 ! melanosome localization GO:0032400 16 10 0,000 0,04361918 0,09157744 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,04361918 0,0914976 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,04361918 0,0914179 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,04361918 0,09133834 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04361918 0,09125891 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,04361918 0,09117963 ! mRNA cleavage GO:0006379 17 10 0,000 0,04361918 0,09110048 ! protein sumoylation GO:0016925 15 10 0,000 0,04361918 0,09102147 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04361918 0,09094259 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04361918 0,09086385 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04361918 0,09078525 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,04361918 0,09070678 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,04361918 0,09062845 ! salivary gland development GO:0007431 27 10 0,000 0,04361918 0,09055026 ! prophase GO:0051324 15 10 0,000 0,04361918 0,0904722 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,04361918 0,09039427 ! apical protein localization GO:0045176 15 10 0,000 0,04361918 0,09031648 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,04361918 0,09023882 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,04361918 0,0901613 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,04361918 0,09008391 ! midbrain development GO:0030901 13 10 0,000 0,04361918 0,09000665 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,04361918 0,08992952 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,04361918 0,08985253 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,04361918 0,08977566 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,04361918 0,08969893 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04361918 0,08962233 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04361918 0,08954586 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,04361918 0,08946952 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 0,000 0,04361918 0,08939331 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 0,000 0,04361918 0,08931723 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04361918 0,08924128 ! blastocyst formation GO:0001825 17 10 0,000 0,04361918 0,08916546 ! cerebellar cortex development GO:0021695 15 10 0,000 0,04361918 0,08908977 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,04361918 0,08901421 ! activation of innate immune response GO:0002218 12 10 0,000 0,04361918 0,08893877 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,04361918 0,08886346 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,04361918 0,08878828 ! response to nicotine GO:0035094 20 10 0,000 0,04361918 0,08871323 ! establishment of cell polarity GO:0030010 16 10 0,000 0,04361918 0,0886383 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,04361918 0,0885635 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,04361918 0,08848883 ! regulation of vesicle-mediated transport GO:0060627 119 75 1,000 0,04415655 0,08950351 ! lymphocyte differentiation GO:0030098 167 75 1,000 0,04415655 0,08942817 ! development of primary sexual characteristics GO:0045137 124 76 1,000 0,04522084 0,0915066 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,04629459 0,09360066 ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 1,000 0,04737768 0,09571008 ! negative regulation of organelle organization GO:0010639 161 78 1,000 0,04737768 0,09562978 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,04787583 0,09655428 ! respiratory burst GO:0045730 17 11 0,000 0,04787583 0,09647341 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,04787583 0,09639268 ! neuron fate specification GO:0048665 17 11 0,000 0,04787583 0,09631209 ! telencephalon cell migration GO:0022029 20 11 0,000 0,04787583 0,09623163 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,04787583 0,0961513 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,04787583 0,09607111 ! thyroid gland development GO:0030878 26 11 0,000 0,04787583 0,09599105 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,04787583 0,09591112 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,04787583 0,09583133 ! response to pain GO:0048265 24 11 0,000 0,04787583 0,09575167 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,04787583 0,09567214 ! T cell proliferation GO:0042098 26 11 0,000 0,04787583 0,09559274 ! blood vessel remodeling GO:0001974 29 11 0,000 0,04787583 0,09551348 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,04787583 0,09543435 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,04787583 0,09535534 ! bone resorption GO:0045453 16 11 0,000 0,04787583 0,09527647 ! ventral spinal cord development GO:0021517 21 11 0,000 0,04787583 0,09519773 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,04787583 0,09511912 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,04787583 0,09504064 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,04787583 0,09496229 ! melanocyte differentiation GO:0030318 21 11 0,000 0,04787583 0,09488407 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,04787583 0,09480597 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,04787583 0,09472801 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,04787583 0,09465017 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,04787583 0,09457246 GO:0043088|regulation of Cdc42 GTPase activity, ! lipid digestion GO:0044241 18 11 0,000 0,04787583 0,09449488 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,04787583 0,09441742 ! UV protection GO:0009650 19 11 0,000 0,04787583 0,09434009 ! adult heart development GO:0007512 14 11 0,000 0,04787583 0,09426289 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,04787583 0,09418582 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,04787583 0,09410887 ! temperature homeostasis GO:0001659 17 11 0,000 0,04787583 0,09403205 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,04787583 0,09395535 ! negative regulation of ossification GO:0030279 26 11 0,000 0,04787583 0,09387877 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,04787583 0,09380233 ! regulation of organ growth GO:0046620 13 11 0,000 0,04787583 0,093726 ! pigment granule localization GO:0051875 20 11 0,000 0,04787583 0,0936498 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,04787583 0,09357372 ! vasoconstriction GO:0042310 18 11 0,000 0,04787583 0,09349777 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,04787583 0,09342194 ! embryonic axis specification GO:0000578 18 11 0,000 0,04787583 0,09334624 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,04787583 0,09327065 ! snRNA metabolic process GO:0016073 24 11 0,000 0,04787583 0,09319519 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,04787583 0,09311985 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,04787583 0,09304463 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,04787583 0,09296954 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,04787583 0,09289456 ! zymogen activation GO:0031638 15 11 0,000 0,04787583 0,09281971 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,04787583 0,09274497 ! neuroblast proliferation GO:0007405 24 11 0,000 0,04787583 0,09267036 ! nucleosome positioning GO:0016584 15 11 0,000 0,04787583 0,09259586 ! regulation of isotype switching GO:0045191 22 11 0,000 0,04787583 0,09252149 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,04787583 0,09244724 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,04787583 0,0923731 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,04787583 0,09229908 ! acid secretion GO:0046717 18 11 0,000 0,04787583 0,09222518 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,04787583 0,0921514 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,04787583 0,09207774 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,04787583 0,0920042 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,04787583 0,09193077 ! oocyte differentiation GO:0009994 18 11 0,000 0,04787583 0,09185746 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,04787583 0,09178427 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,04787583 0,09171119 ! cholesterol efflux GO:0033344 19 11 0,000 0,04787583 0,09163823 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,04787583 0,09156539 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,04787583 0,09149266 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,04787583 0,09142004 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,04787583 0,09134755 ! embryonic gut development GO:0048566 15 11 0,000 0,04787583 0,09127516 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,04787583 0,09120289 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,04787583 0,09113074 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,04787583 0,0910587 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,04787583 0,09098677 ! defense response to fungus GO:0050832 13 11 0,000 0,04787583 0,09091496 ! developmental induction GO:0031128 19 11 0,000 0,04787583 0,09084326 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,04787583 0,09077167 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,04787583 0,0907002 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,04787583 0,09062884 ! sequestering of metal ion GO:0051238 14 11 0,000 0,04787583 0,09055759 ! lamellipodium assembly GO:0030032 20 11 0,000 0,04787583 0,09048645 ! regulation of embryonic development GO:0045995 27 11 0,000 0,04787583 0,09041543 ! nucleus localization GO:0051647 19 11 0,000 0,04787583 0,09034451 ! regulation of synapse organization GO:0050807 17 11 0,000 0,04787583 0,09027371 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,04847002 0,09132252 ! response to metal ion GO:0010038 140 80 1,000 0,0495715 0,09332474 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,0495715 0,09325178 ! protein import into nucleus GO:0006606 158 80 1,000 0,0495715 0,09317892 ! T cell activation GO:0042110 168 81 1,000 0,05068202 0,09519199 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,05068202 0,09511774 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 0,05068202 0,0950436 ! nuclear import GO:0051170 161 81 1,000 0,05068202 0,09496958 ! response to drug GO:0042493 143 82 1,000 0,05180148 0,09699172 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,05211368 0,0975004 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,05211368 0,09742464 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,05211368 0,097349 ! positive regulation of cellular catabolic process GO:0031331 31 12 0,000 0,05211368 0,09727348 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,05211368 0,09719807 ! virus-host interaction GO:0019048 29 12 0,000 0,05211368 0,09712279 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,05211368 0,09704761 ! cartilage condensation GO:0001502 20 12 0,000 0,05211368 0,09697256 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,05211368 0,09689762 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,05211368 0,09682279 ! protein complex disassembly GO:0043241 27 12 0,000 0,05211368 0,09674808 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05211368 0,09667349 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,05211368 0,09659901 ! hippocampus development GO:0021766 26 12 0,000 0,05211368 0,09652465 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,05211368 0,0964504 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05211368 0,09637626 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,05211368 0,09630224 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,05211368 0,09622833 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,05211368 0,09615454 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,05211368 0,09608086 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,05211368 0,09600729 ! drug transport GO:0015893 16 12 0,000 0,05211368 0,09593383 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,05211368 0,09586049 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,05211368 0,09578725 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,05211368 0,09571413 ! polyamine metabolic process GO:0006595 17 12 0,000 0,05211368 0,09564113 ! focal adhesion formation GO:0048041 35 12 0,000 0,05211368 0,09556823 ! mitotic spindle organization GO:0007052 21 12 0,000 0,05211368 0,09549544 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,05211368 0,09542277 ! forebrain cell migration GO:0021885 21 12 0,000 0,05211368 0,0953502 ! asymmetric protein localization GO:0008105 20 12 0,000 0,05211368 0,09527775 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,05211368 0,0952054 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,05211368 0,09513317 ! entry into host cell GO:0030260 32 12 0,000 0,05211368 0,09506104 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,05211368 0,09498903 ! monoamine transport GO:0015844 18 12 0,000 0,05211368 0,09491712 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05211368 0,09484532 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,05211368 0,09477363 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,05211368 0,09470205 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,05211368 0,09463058 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05211368 0,09455921 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,05211368 0,09448796 ! protein homotetramerization GO:0051289 21 12 0,000 0,05211368 0,0944168 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,05211368 0,09434576 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,05211368 0,09427482 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,05211368 0,09420399 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,05211368 0,09413327 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,05211368 0,09406265 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05211368 0,09399214 ! cranial nerve development GO:0021545 20 12 0,000 0,05211368 0,09392174 ! fucose catabolic process GO:0019317 22 12 0,000 0,05211368 0,09385143 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,05211368 0,09378124 ! histone methylation GO:0016571 26 12 0,000 0,05211368 0,09371115 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,05211368 0,09364116 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05211368 0,09357128 ! gland morphogenesis GO:0022612 29 12 0,000 0,05211368 0,0935015 ! T cell homeostasis GO:0043029 25 12 0,000 0,05211368 0,09343183 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,05211368 0,09336226 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,05211368 0,09329279 ! spleen development GO:0048536 22 12 0,000 0,05211368 0,09322343 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,05211368 0,09315417 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,05211368 0,09308502 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,05211368 0,09301596 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,05211368 0,09294701 ! negative regulation of mast cell proliferation GO:0070667 23 12 0,000 0,05211368 0,09287816 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,05211368 0,09280941 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,05211368 0,09274077 ! response to cold GO:0009409 17 12 0,000 0,05211368 0,09267222 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,05211368 0,09260378 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,05211368 0,09253544 ! response to oxygen levels GO:0070482 176 83 1,000 0,05292978 0,09391523 ! negative regulation of transport GO:0051051 153 84 1,000 0,05406682 0,09586203 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,0552125 0,09782127 GO:0002696|positive regulation of leukocyte activation, ! cGMP metabolic process GO:0046068 18 13 0,000 0,05633281 0,09973269 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,05633281 0,09965936 ! regulation of chemokine production GO:0032642 18 13 0,000 0,05633281 0,09958614 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05633281 0,09951302 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,05633281 0,09944001 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,05633281 0,09936711 ! lipid localization GO:0010876 28 13 0,000 0,05633281 0,09929431 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,05633281 0,09922162 ! organelle fusion GO:0048284 32 13 0,000 0,05633281 0,09914904 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,05633281 0,09907656 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,05633281 0,09900419 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,05633281 0,09893192 ! endocrine pancreas development GO:0031018 22 13 0,000 0,05633281 0,09885976 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,05633281 0,09878771 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,05633281 0,09871576 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,05633281 0,09864391 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05633281 0,09857217 ! methionine metabolic process GO:0006555 27 13 0,000 0,05633281 0,09850053 ! plasma membrane organization GO:0007009 24 13 0,000 0,05633281 0,098429 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,05633281 0,09835757 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,05633281 0,09828624 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,05633281 0,09821502 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,05633281 0,0981439 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,05633281 0,09807289 ! cytokine metabolic process GO:0042107 22 13 0,000 0,05633281 0,09800198 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,05633281 0,09793116 ! exocrine system development GO:0035272 32 13 0,000 0,05633281 0,09786046 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 0,000 0,05633281 0,09778985 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,05633281 0,09771935 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,05633281 0,09764894 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,05633281 0,09757864 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,05633281 0,09750844 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,05633281 0,09743834 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,05633281 0,09736834 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,05633281 0,09729844 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,05633281 0,09722865 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,05633281 0,09715895 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05633281 0,09708935 ! ribosome assembly GO:0042255 17 13 0,000 0,05633281 0,09701985 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,05633281 0,09695045 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,05633281 0,09688115 ! chromatin silencing GO:0006342 26 13 0,000 0,05633281 0,09681195 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,05633281 0,09674285 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05633281 0,09667385 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,05633281 0,09660494 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,05633281 0,09653613 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,05633281 0,09646742 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,05633281 0,09639881 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05633281 0,0963303 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,05633281 0,09626188 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,05633281 0,09619356 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,05633281 0,09612534 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,05633281 0,09605722 ! embryonic placenta development GO:0001892 23 13 0,000 0,05633281 0,09598919 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,05633281 0,09592125 ! insulin secretion GO:0030073 23 13 0,000 0,05633281 0,09585342 ! actin filament polymerization GO:0030041 24 13 0,000 0,05633281 0,09578568 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,05633281 0,09571803 ! acrosome reaction GO:0007340 18 13 0,000 0,05633281 0,09565048 ! response to inorganic substance GO:0010035 153 86 1,000 0,05636673 0,09564059 ! mitochondrion organization GO:0007005 148 86 1,000 0,05636673 0,09557319 ! alcohol catabolic process GO:0046164 130 86 1,000 0,05636673 0,09550588 ! nitrogen compound catabolic process GO:0044270 143 87 1,000 0,0575294 0,09740728 ! protein localization in nucleus GO:0034504 176 87 1,000 0,0575294 0,09733878 ! regulation of DNA binding GO:0051101 155 88 1,000 0,05870042 0,09925033 ! gland development GO:0048732 206 88 1,000 0,05870042 0,09918063 ! rRNA transcription GO:0009303 25 14 0,000 0,06053329 0,10220568 ! lactation GO:0007595 26 14 0,000 0,06053329 0,10213401 ! reproductive cellular process GO:0048610 20 14 0,000 0,06053329 0,10206244 ! tRNA modification GO:0006400 20 14 0,000 0,06053329 0,10199097 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,06053329 0,10191959 ! regulation of S phase GO:0033261 23 14 0,000 0,06053329 0,10184832 ! water transport GO:0006833 21 14 0,000 0,06053329 0,10177715 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,06053329 0,10170607 ! non-recombinational repair GO:0000726 25 14 0,000 0,06053329 0,1016351 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,06053329 0,10156423 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,06053329 0,10149345 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,06053329 0,10142277 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,06053329 0,10135219 ! RNA polyadenylation GO:0043631 30 14 0,000 0,06053329 0,10128171 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,06053329 0,10121133 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,06053329 0,10114104 ! regulated secretory pathway GO:0045055 23 14 0,000 0,06053329 0,10107085 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,06053329 0,10100076 ! arginine metabolic process GO:0006525 17 14 0,000 0,06053329 0,10093077 ! regulation of heart rate GO:0002027 24 14 0,000 0,06053329 0,10086087 ! organic alcohol transport GO:0015850 29 14 0,000 0,06053329 0,10079107 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,06053329 0,10072137 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,06053329 0,10065176 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,06053329 0,10058225 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,06053329 0,10051284 ! neutral amino acid transport GO:0015804 26 14 0,000 0,06053329 0,10044352 ! L-amino acid transport GO:0015807 30 14 0,000 0,06053329 0,10037429 ! stem cell development GO:0048864 43 14 0,000 0,06053329 0,10030516 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,06053329 0,10023613 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,06053329 0,10016719 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,06053329 0,10009835 ! cerebellum development GO:0021549 21 14 0,000 0,06053329 0,1000296 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,06053329 0,09996095 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,06053329 0,09989239 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,06053329 0,09982392 ! cofactor transport GO:0051181 26 14 0,000 0,06053329 0,09975555 ! NADP metabolic process GO:0006739 24 14 0,000 0,06053329 0,09968727 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,06053329 0,09961908 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,06053329 0,09955099 ! intestinal absorption GO:0050892 25 14 0,000 0,06053329 0,09948299 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,06053329 0,09941508 ! oxygen transport GO:0015671 21 14 0,000 0,06053329 0,09934727 ! male genitalia development GO:0030539 24 14 0,000 0,06053329 0,09927955 ! regulation of RNA stability GO:0043487 32 14 0,000 0,06053329 0,09921192 ! regulation of axon extension GO:0030516 37 14 0,000 0,06053329 0,09914438 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,06053329 0,09907694 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,06106713 0,09988274 ! positive regulation of MAP kinase activity GO:0043406 160 93 1,000 0,06467743 0,10571597 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,06471522 0,10570592 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06471522 0,1056342 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,06471522 0,10556259 ! superoxide anion generation GO:0042554 20 15 0,000 0,06471522 0,10549107 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,06471522 0,10541964 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,06471522 0,10534832 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,06471522 0,10527709 ! copper ion transport GO:0006825 20 15 0,000 0,06471522 0,10520596 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,06471522 0,10513492 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,06471522 0,10506398 ! sulfate transport GO:0008272 23 15 0,000 0,06471522 0,10499313 ! response to cAMP GO:0051591 22 15 0,000 0,06471522 0,10492238 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,06471522 0,10485173 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,06471522 0,10478117 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,06471522 0,1047107 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,06471522 0,10464033 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,06471522 0,10457006 ! response to hexose stimulus GO:0009746 22 15 0,000 0,06471522 0,10449988 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,06471522 0,10442979 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,06471522 0,1043598 ! pituitary gland development GO:0021983 29 15 0,000 0,06471522 0,1042899 ! vesicle coating GO:0006901 33 15 0,000 0,06471522 0,10422009 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,06471522 0,10415038 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,06471522 0,10408076 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,06471522 0,10401123 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,06471522 0,1039418 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,06471522 0,10387246 ! regulation of vasodilation GO:0042312 26 15 0,000 0,06471522 0,10380321 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,06471522 0,10373405 ! histone deacetylation GO:0016575 20 15 0,000 0,06471522 0,10366499 ! mRNA splice site selection GO:0006376 38 15 0,000 0,06471522 0,10359602 ! tissue regeneration GO:0042246 26 15 0,000 0,06471522 0,10352714 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,06471522 0,10345835 ! water homeostasis GO:0030104 27 15 0,000 0,06471522 0,10338965 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,06471522 0,10332104 ! muscle maintenance GO:0046716 26 15 0,000 0,06471522 0,10325253 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,06471522 0,10318411 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,06471522 0,10311577 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,06471522 0,10304753 ! heme biosynthetic process GO:0006783 29 15 0,000 0,06471522 0,10297937 ! cell killing GO:0001906 29 15 0,000 0,06471522 0,10291131 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,06471522 0,10284334 ! detection of bacterium GO:0016045 18 15 0,000 0,06471522 0,10277546 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,06471522 0,10270766 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,06471522 0,10263996 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,06471522 0,10257234 ! peptide hormone processing GO:0016486 23 15 0,000 0,06471522 0,10250482 ! transcription initiation GO:0006352 153 94 1,000 0,06589656 0,10430732 ! forebrain development GO:0030900 188 95 1,000 0,06712337 0,10617938 ! regulation of Rho protein signal transduction GO:0035023 213 95 1,000 0,06712337 0,10610962 ! leukocyte differentiation GO:0002521 202 96 1,000 0,06835779 0,10799005 ! detection of stimulus GO:0051606 151 96 1,000 0,06835779 0,10791919 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,06887867 0,10867021 ! regulation of glucose metabolic process GO:0010906 28 16 0,000 0,06887867 0,108599 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,06887867 0,10852788 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,06887867 0,10845685 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,06887867 0,10838592 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,06887867 0,10831508 ! bone remodeling GO:0046849 27 16 0,000 0,06887867 0,10824433 ! filopodium assembly GO:0046847 32 16 0,000 0,06887867 0,10817368 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,06887867 0,10810311 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,06887867 0,10803264 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,06887867 0,10796226 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,06887867 0,10789198 ! startle response GO:0001964 28 16 0,000 0,06887867 0,10782178 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,06887867 0,10775167 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,06887867 0,10768166 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,06887867 0,10761174 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,06887867 0,1075419 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,06887867 0,10747216 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,06887867 0,10740251 ! protein polyubiquitination GO:0000209 34 16 0,000 0,06887867 0,10733295 ! glutamate metabolic process GO:0006536 22 16 0,000 0,06887867 0,10726348 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,06887867 0,1071941 ! response to osmotic stress GO:0006970 25 16 0,000 0,06887867 0,10712481 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,06887867 0,1070556 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,06887867 0,10698649 ! fructose metabolic process GO:0006000 25 16 0,000 0,06887867 0,10691747 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,06887867 0,10684853 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,06887867 0,10677969 ! intermediate filament-based process GO:0045103 32 16 0,000 0,06887867 0,10671093 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,06887867 0,10664226 ! negative regulation of immune response GO:0050777 35 16 0,000 0,06887867 0,10657368 ! axon cargo transport GO:0008088 43 16 0,000 0,06887867 0,10650519 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,06887867 0,10643679 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,06887867 0,10636847 ! DNA replication initiation GO:0006270 27 16 0,000 0,06887867 0,10630024 ! neuron recognition GO:0008038 35 16 0,000 0,06887867 0,1062321 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,06887867 0,10616405 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,06887867 0,10609608 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,06887867 0,1060282 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,06887867 0,10596041 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,06887867 0,1058927 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,06887867 0,10582508 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,06887867 0,10575755 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,06887867 0,1056901 ! negative regulation of leukocyte proliferation GO:0070664 31 16 0,000 0,06887867 0,10562274 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 0,000 0,06887867 0,10555546 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,06959971 0,10659256 ! protein ubiquitination GO:0016567 217 97 1,000 0,06959971 0,10652475 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,07302372 0,11169426 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,07302372 0,1116233 ! metencephalon development GO:0022037 30 17 0,000 0,07302372 0,11155243 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,07302372 0,11148165 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,07302372 0,11141095 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,07302372 0,11134035 ! signal complex assembly GO:0007172 41 17 0,000 0,07302372 0,11126984 ! endothelial cell migration GO:0043542 28 17 0,000 0,07302372 0,11119941 ! inositol metabolic process GO:0006020 28 17 0,000 0,07302372 0,11112908 ! gene silencing by RNA GO:0031047 36 17 0,000 0,07302372 0,11105883 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,07302372 0,11098868 ! glial cell development GO:0021782 27 17 0,000 0,07302372 0,11091861 ! limbic system development GO:0021761 36 17 0,000 0,07302372 0,11084863 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,07302372 0,11077873 ! adult walking behavior GO:0007628 33 17 0,000 0,07302372 0,11070893 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,07302372 0,11063921 ! heart looping GO:0001947 30 17 0,000 0,07302372 0,11056959 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,07302372 0,11050005 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,07302372 0,11043059 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,07302372 0,11036123 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,07302372 0,11029195 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,07302372 0,11022276 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,07302372 0,11015365 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,07302372 0,11008463 ! glycine metabolic process GO:0006544 28 17 0,000 0,07302372 0,1100157 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,07302372 0,10994685 ! NAD metabolic process GO:0019674 29 17 0,000 0,07302372 0,10987809 ! membrane budding GO:0006900 37 17 0,000 0,07302372 0,10980942 ! DNA integration GO:0015074 29 17 0,000 0,07302372 0,10974083 ! regulation of protein binding GO:0043393 33 17 0,000 0,07302372 0,10967233 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,07302372 0,10960391 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,07302372 0,10953558 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,07302372 0,10946734 ! genitalia development GO:0048806 30 17 0,000 0,07302372 0,10939917 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,07302372 0,1093311 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,07302372 0,10926311 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,07302372 0,1091952 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,07302372 0,10912737 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,07302372 0,10905964 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,07302372 0,10899198 ! steroid catabolic process GO:0006706 31 17 0,000 0,07302372 0,10892441 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,07302372 0,10885692 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,07302372 0,10878952 ! gas transport GO:0015669 25 17 0,000 0,07302372 0,1087222 ! organic cation transport GO:0015695 31 17 0,000 0,07302372 0,10865496 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,07302372 0,10858781 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,07302372 0,10852074 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,07302372 0,10845375 ! microspike assembly GO:0030035 36 17 0,000 0,07302372 0,10838684 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,07302372 0,10832002 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,07302372 0,10825328 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,07715046 0,1143005 ! neuron maturation GO:0042551 42 18 0,000 0,07715046 0,11423016 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,07715046 0,11415991 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,07715046 0,11408974 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,07715046 0,11401966 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,07715046 0,11394967 ! memory GO:0007613 31 18 0,000 0,07715046 0,11387976 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,07715046 0,11380994 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,07715046 0,1137402 ! patterning of blood vessels GO:0001569 39 18 0,000 0,07715046 0,11367055 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,07715046 0,11360098 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,07715046 0,1135315 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,07715046 0,11346211 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,07715046 0,1133928 ! glutamine metabolic process GO:0006541 29 18 0,000 0,07715046 0,11332357 ! response to retinoic acid GO:0032526 26 18 0,000 0,07715046 0,11325443 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,07715046 0,11318537 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,07715046 0,1131164 ! response to fungus GO:0009620 21 18 0,000 0,07715046 0,11304751 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,07715046 0,1129787 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,07715046 0,11290998 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,07715046 0,11284134 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,07715046 0,11277279 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,07715046 0,11270431 ! vitamin transport GO:0051180 27 18 0,000 0,07715046 0,11263593 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,07715046 0,11256762 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,07715046 0,1124994 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,07715046 0,11243126 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,07715046 0,1123632 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 0,000 0,07715046 0,11229522 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,07715046 0,11222733 ! nerve development GO:0021675 28 18 0,000 0,07715046 0,11215952 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,07715046 0,11209179 ! protein secretion GO:0009306 39 19 0,000 0,08125896 0,11798978 ! positive regulation of translation GO:0045727 30 19 0,000 0,08125896 0,11791862 ! negative regulation of defense response GO:0031348 25 19 0,000 0,08125896 0,11784754 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,08125896 0,11777654 ! skin development GO:0043588 36 19 0,000 0,08125896 0,11770564 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,08125896 0,11763482 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,08125896 0,11756408 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,08125896 0,11749343 ! bile acid metabolic process GO:0008206 29 19 0,000 0,08125896 0,11742286 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,08125896 0,11735238 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,08125896 0,11728198 ! cerebral cortex development GO:0021987 36 19 0,000 0,08125896 0,11721167 ! pigmentation during development GO:0048066 41 19 0,000 0,08125896 0,11714144 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,08125896 0,1170713 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,08125896 0,11700124 ! heme metabolic process GO:0042168 36 19 0,000 0,08125896 0,11693126 ! actin filament bundle formation GO:0051017 42 19 0,000 0,08125896 0,11686137 ! neuromuscular junction development GO:0007528 34 19 0,000 0,08125896 0,11679156 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,08125896 0,11672183 ! plasma membrane fusion GO:0045026 28 19 0,000 0,08125896 0,11665219 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,08125896 0,11658263 ! peptide cross-linking GO:0018149 37 19 0,000 0,08125896 0,11651315 ! protein export from nucleus GO:0006611 36 19 0,000 0,08125896 0,11644375 ! heart process GO:0003015 30 19 0,000 0,08125896 0,11637444 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,08125896 0,11630521 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,08125896 0,11623607 ! visual learning GO:0008542 36 19 0,000 0,08125896 0,116167 ! cellular pigmentation GO:0033059 36 19 0,000 0,08125896 0,11609802 ! G1 phase GO:0051318 40 19 0,000 0,08125896 0,11602912 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,08125896 0,1159603 ! cell-cell junction organization GO:0045216 35 19 0,000 0,08125896 0,11589156 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,08125896 0,11582291 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,08125896 0,11575433 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,08125896 0,11568584 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,08125896 0,11561742 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,08125896 0,11554909 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,08125896 0,11548084 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,08125896 0,11541267 ! cilium assembly GO:0042384 37 19 0,000 0,08125896 0,11534458 ! peptide hormone secretion GO:0030072 31 19 0,000 0,08125896 0,11527657 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,08534931 0,12100792 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,08534931 0,12093666 ! positive regulation of ossification GO:0045778 47 20 0,000 0,08534931 0,12086547 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,08534931 0,12079438 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,08534931 0,12072336 ! cAMP metabolic process GO:0046058 36 20 0,000 0,08534931 0,12065243 ! response to vitamin GO:0033273 31 20 0,000 0,08534931 0,12058159 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,08534931 0,12051082 ! regulation of carbohydrate metabolic process GO:0006109 38 20 0,000 0,08534931 0,12044014 GO:0010675|regulation of cellular carbohydrate metabolic process, ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,08534931 0,12036954 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,08534931 0,12029903 ! response to alkaloid GO:0043279 38 20 0,000 0,08534931 0,1202286 ! retinoid metabolic process GO:0001523 32 20 0,000 0,08534931 0,12015825 GO:0016101|diterpenoid metabolic process, ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,08534931 0,12008798 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,08534931 0,12001779 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,08534931 0,11994769 GO:0032392|DNA geometric change, ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,08534931 0,11987767 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,08534931 0,11980773 ! body fluid secretion GO:0007589 31 20 0,000 0,08534931 0,11973787 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,08534931 0,11966809 ! peptide secretion GO:0002790 35 20 0,000 0,08534931 0,11959839 ! stem cell differentiation GO:0048863 53 20 0,000 0,08534931 0,11952878 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,08534931 0,11945924 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,08534931 0,11938979 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,08534931 0,11932042 ! sensory perception of pain GO:0019233 30 20 0,000 0,08534931 0,11925113 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,08534931 0,11918192 ! diencephalon development GO:0021536 34 20 0,000 0,08534931 0,11911279 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,08534931 0,11904373 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,08534931 0,11897476 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,08534931 0,11890587 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,08534931 0,11883706 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,08534931 0,11876833 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,08534931 0,11869968 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,08534931 0,1186311 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,08534931 0,11856261 ! regulation of glucose import GO:0046324 29 20 0,000 0,08534931 0,1184942 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,08534931 0,11842586 ! actin filament-based movement GO:0030048 43 20 0,000 0,08534931 0,1183576 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,08534931 0,11828943 ! negative regulation of T cell activation GO:0050868 40 20 0,000 0,08534931 0,11822133 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,08534931 0,1181533 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,08534931 0,11808536 ! regulation of cell killing GO:0031341 42 21 0,000 0,08942158 0,12364847 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,08942158 0,12357744 ! hormone secretion GO:0046879 38 21 0,000 0,08942158 0,1235065 ! glycerol metabolic process GO:0006071 34 21 0,000 0,08942158 0,12343565 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,08942158 0,12336487 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,08942158 0,12329417 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,08942158 0,12322356 ! axis specification GO:0009798 38 21 0,000 0,08942158 0,12315302 ! ovarian follicle development GO:0001541 35 21 0,000 0,08942158 0,12308257 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,08942158 0,1230122 ! smooth muscle contraction GO:0006939 46 21 0,000 0,08942158 0,1229419 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,08942158 0,12287169 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,08942158 0,12280156 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,08942158 0,12273151 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,08942158 0,12266153 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,08942158 0,12259164 ! cytolysis GO:0019835 24 21 0,000 0,08942158 0,12252183 ! vasodilation GO:0042311 39 21 0,000 0,08942158 0,12245209 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,08942158 0,12238244 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,08942158 0,12231287 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,08942158 0,12224337 ! oogenesis GO:0048477 36 21 0,000 0,08942158 0,12217395 ! DNA modification GO:0006304 34 21 0,000 0,08942158 0,12210461 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,08942158 0,12203535 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,08942158 0,12196617 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,08942158 0,12189707 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,08942158 0,12182805 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,08942158 0,1217591 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,08942158 0,12169023 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,08942158 0,12162144 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,08942158 0,12155273 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,08942158 0,12148409 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,08942158 0,12141554 ! collagen catabolic process GO:0030574 28 21 0,000 0,08942158 0,12134706 ! sperm-egg recognition GO:0035036 21 21 0,000 0,08942158 0,12127865 ! gut development GO:0048565 39 21 0,000 0,08942158 0,12121033 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,09347586 0,12663453 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,09347586 0,12656326 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,09347586 0,12649208 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,09347586 0,12642098 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,09347586 0,12634995 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,09347586 0,12627901 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,09347586 0,12620815 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,09347586 0,12613736 ! regeneration GO:0031099 41 22 0,000 0,09347586 0,12606666 ! keratinization GO:0031424 28 22 0,000 0,09347586 0,12599603 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,09347586 0,12592549 ! sensory perception of taste GO:0050909 28 22 0,000 0,09347586 0,12585502 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,09347586 0,12578463 ! vacuolar transport GO:0007034 36 22 0,000 0,09347586 0,12571432 ! lysosome organization GO:0007040 41 22 0,000 0,09347586 0,12564409 ! central nervous system neuron development GO:0021954 46 22 0,000 0,09347586 0,12557394 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,09347586 0,12550386 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,09347586 0,12543386 ! fucose metabolic process GO:0006004 39 22 0,000 0,09347586 0,12536395 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,09347586 0,12529411 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,09347586 0,12522434 ! ureteric bud development GO:0001657 43 22 0,000 0,09347586 0,12515466 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,09347586 0,12508505 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,09347586 0,12501552 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,09347586 0,12494607 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,09347586 0,12487669 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,09347586 0,12480739 ! sarcomere organization GO:0045214 30 22 0,000 0,09347586 0,12473817 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,09347586 0,12466902 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,09347586 0,12459996 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,09347586 0,12453096 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,09347586 0,12446205 ! positive regulation of DNA replication GO:0045740 43 23 0,000 0,09751222 0,1297646 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,09751222 0,12969287 ! positive regulation of cell adhesion GO:0045785 56 23 0,000 0,09751222 0,12962122 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,09751222 0,12954964 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,09751222 0,12947815 ! gluconeogenesis GO:0006094 33 23 0,000 0,09751222 0,12940673 ! viral genome replication GO:0019079 41 23 0,000 0,09751222 0,12933539 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,09751222 0,12926413 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,09751222 0,12919295 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,09751222 0,12912185 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,09751222 0,12905083 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,09751222 0,12897988 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,09751222 0,12890901 ! visual behavior GO:0007632 42 23 0,000 0,09751222 0,12883822 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,09751222 0,12876751 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,09751222 0,12869687 ! response to ethanol GO:0045471 46 23 0,000 0,09751222 0,12862632 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,09751222 0,12855584 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,09751222 0,12848543 ! peroxisome organization GO:0007031 37 23 0,000 0,09751222 0,12841511 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,09751222 0,12834486 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,09751222 0,12827469 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,09751222 0,12820459 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,09751222 0,12813457 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 38 23 0,000 0,09751222 0,12806463 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,09751222 0,12799476 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,09751222 0,12792497 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,09751222 0,12785526 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,09751222 0,12778562 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,09751222 0,12771606 ! fatty acid transport GO:0015908 44 23 0,000 0,09751222 0,12764657 ! platelet activation GO:0030168 37 23 0,000 0,09751222 0,12757716 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,09751222 0,12750783 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,09751222 0,12743857 ! hormone transport GO:0009914 40 23 0,000 0,09751222 0,12736938 ! cell-cell recognition GO:0009988 25 23 0,000 0,09751222 0,12730027 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,09751222 0,12723124 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,09751222 0,12716228 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,09751222 0,12709339 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,09751222 0,12702458 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,10153074 0,13218775 GO:0016444|somatic cell DNA recombination, ! regulation of cellular catabolic process GO:0031329 52 24 0,000 0,10153074 0,13211626 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,10153074 0,13204484 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,10153074 0,13197351 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,10153074 0,13190225 ! vesicle docking GO:0048278 47 24 0,000 0,10153074 0,13183106 ! spinal cord development GO:0021510 47 24 0,000 0,10153074 0,13175996 ! vacuole organization GO:0007033 43 24 0,000 0,10153074 0,13168893 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,10153074 0,13161797 ! digestive system process GO:0022600 39 24 0,000 0,10153074 0,1315471 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,10153074 0,1314763 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,10153074 0,13140557 ! regulation of behavior GO:0050795 43 24 0,000 0,10153074 0,13133493 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,10153074 0,13126435 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,10153074 0,13119386 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,10153074 0,13112344 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,10153074 0,13105309 ! membrane depolarization GO:0051899 39 24 0,000 0,10153074 0,13098282 ! pallium development GO:0021543 49 24 0,000 0,10153074 0,13091263 ! pentose metabolic process GO:0019321 35 24 0,000 0,10153074 0,13084251 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,10153074 0,13077246 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,10153074 0,13070249 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,10153074 0,1306326 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,10153074 0,13056278 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,10153074 0,13049303 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,10153074 0,13042336 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,10153074 0,13035377 ! regulation of amine transport GO:0051952 40 24 0,000 0,10153074 0,13028425 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,1055315 0,13534584 ! myelination GO:0042552 45 25 0,000 0,1055315 0,13527373 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,1055315 0,1352017 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,1055315 0,13512974 ! phototransduction GO:0007602 33 25 0,000 0,1055315 0,13505787 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,1055315 0,13498607 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,1055315 0,13491434 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,1055315 0,13484269 ! receptor metabolic process GO:0043112 46 25 0,000 0,1055315 0,13477112 ! chromosome condensation GO:0030261 45 25 0,000 0,1055315 0,13469962 ! osteoblast differentiation GO:0001649 60 25 0,000 0,1055315 0,1346282 ! neural crest cell development GO:0014032 54 25 0,000 0,1055315 0,13455686 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,1055315 0,13448559 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,1055315 0,13441439 ! interaction with host GO:0051701 62 25 0,000 0,1055315 0,13434328 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,1055315 0,13427223 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,1055315 0,13420126 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,1055315 0,13413037 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,1055315 0,13405955 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,1055315 0,13398881 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,1055315 0,13391814 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,1055315 0,13384754 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,1055315 0,13377702 ! telomere organization GO:0032200 43 25 0,000 0,1055315 0,13370658 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,1055315 0,13363621 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,1055315 0,13356591 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,10951458 0,13853421 ! embryonic pattern specification GO:0009880 44 26 0,000 0,10951458 0,13846142 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,10951458 0,1383887 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,10951458 0,13831605 ! initiation of viral infection GO:0019059 57 26 0,000 0,10951458 0,13824348 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,10951458 0,13817099 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,10951458 0,13809857 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,10951458 0,13802623 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,10951458 0,13795397 ! molting cycle process GO:0022404 50 26 0,000 0,10951458 0,13788178 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,10951458 0,13780966 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,10951458 0,13773762 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,10951458 0,13766566 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,10951458 0,13759377 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,10951458 0,13752196 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 0,000 0,10951458 0,13745022 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,10951458 0,13737856 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,10951458 0,13730697 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,10951458 0,13723546 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,10951458 0,13716402 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,10951458 0,13709265 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,10951458 0,13702136 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,10951458 0,13695014 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,10951458 0,136879 ! blastocyst development GO:0001824 49 26 0,000 0,10951458 0,13680793 ! leukocyte proliferation GO:0070661 52 26 0,000 0,10951458 0,13673694 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,10951458 0,13666601 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,10951458 0,13659517 ! neuron fate commitment GO:0048663 48 27 0,000 0,11348005 0,14146788 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,11348005 0,14139462 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,11348005 0,14132143 ! iron ion transport GO:0006826 59 27 0,000 0,11348005 0,14124832 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,11348005 0,14117529 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,11348005 0,14110233 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,11348005 0,14102944 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,11348005 0,14095664 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,11348005 0,1408839 ! autophagy GO:0006914 41 27 0,000 0,11348005 0,14081124 ! response to toxin GO:0009636 47 27 0,000 0,11348005 0,14073866 ! primary neural tube formation GO:0014020 51 27 0,000 0,11348005 0,14066615 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,11348005 0,14059372 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,11348005 0,14052136 ! glutathione metabolic process GO:0006749 39 27 0,000 0,11348005 0,14044908 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,11348005 0,14037687 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,11348005 0,14030473 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,11348005 0,14023267 ! negative regulation of lymphocyte activation GO:0051250 53 27 0,000 0,11348005 0,14016068 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,117428 0,14496242 ! circadian rhythm GO:0007623 50 28 0,000 0,117428 0,14488808 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,117428 0,14481382 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 59 28 0,000 0,117428 0,14473963 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,117428 0,14466552 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,117428 0,14459148 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,117428 0,14451752 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,117428 0,14444364 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,117428 0,14436983 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,117428 0,1442961 ! synaptogenesis GO:0007416 42 28 0,000 0,117428 0,14422244 ! peptidyl-tyrosine modification GO:0018212 50 28 0,000 0,117428 0,14414886 ! lipid oxidation GO:0034440 43 28 0,000 0,117428 0,14407535 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,117428 0,14400192 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,117428 0,14392856 ! translational initiation GO:0006413 65 29 0,000 0,12135849 0,14867033 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,12135849 0,14859467 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,12135849 0,14851909 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,12135849 0,14844358 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,12135849 0,14836816 ! complement activation, classical pathway GO:0006958 48 29 0,000 0,12135849 0,1482928 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,12135849 0,14821753 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,12135849 0,14814233 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,12135849 0,14806721 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,12135849 0,14799216 ! cell fate determination GO:0001709 60 29 0,000 0,12135849 0,14791719 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,12135849 0,14784229 ! detection of light stimulus GO:0009583 38 29 0,000 0,12135849 0,14776747 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,12135849 0,14769273 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,12135849 0,14761806 ! regulation of coagulation GO:0050818 46 29 0,000 0,12135849 0,14754347 ! zinc ion transport GO:0006829 45 30 0,000 0,12527161 0,15222399 ! membrane docking GO:0022406 61 30 0,000 0,12527161 0,15214715 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,12527161 0,15207038 ! cell junction assembly GO:0034329 78 30 0,000 0,12527161 0,15199369 ! regulation of innate immune response GO:0045088 51 30 0,000 0,12527161 0,15191709 ! acute-phase response GO:0006953 49 30 0,000 0,12527161 0,15184055 ! myofibril assembly GO:0030239 47 30 0,000 0,12527161 0,1517641 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,12527161 0,15168772 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,12527161 0,15161142 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,12527161 0,15153519 ! phospholipid transport GO:0015914 51 30 0,000 0,12527161 0,15145904 ! ensheathment of neurons GO:0007272 57 30 0,000 0,12527161 0,15138297 GO:0008366|axon ensheathment, ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,12527161 0,15130698 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,12527161 0,15123106 ! negative regulation of leukocyte activation GO:0002695 56 30 0,000 0,12527161 0,15115521 ! eye morphogenesis GO:0048592 60 30 0,000 0,12527161 0,15107945 ! response to heat GO:0009408 50 30 0,000 0,12527161 0,15100376 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,12916743 0,15562186 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,12916743 0,15554397 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,12916743 0,15546616 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,12916743 0,15538842 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,12916743 0,15531077 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,12916743 0,15523319 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,12916743 0,15515569 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,12916743 0,15507827 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,12916743 0,15500092 ! ovulation cycle process GO:0022602 49 31 0,000 0,12916743 0,15492365 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,12916743 0,15484646 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,12916743 0,15476935 ! peptide transport GO:0015833 55 31 0,000 0,12916743 0,15469231 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,12916743 0,15461535 ! iron ion homeostasis GO:0055072 54 31 0,000 0,12916743 0,15453846 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,12916743 0,15446165 ! mesoderm formation GO:0001707 69 31 0,000 0,12916743 0,15438492 ! natural killer cell activation GO:0030101 45 31 0,000 0,12916743 0,15430826 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,12916743 0,15423169 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,12916743 0,15415518 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,12916743 0,15407875 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,12916743 0,1540024 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,12916743 0,15392612 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,13304603 0,15846968 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,13304603 0,15839127 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,13304603 0,15831294 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,13304603 0,15823468 ! cholesterol transport GO:0030301 56 32 0,000 0,13304603 0,1581565 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,13304603 0,1580784 ! spliceosome assembly GO:0000245 67 32 0,000 0,13304603 0,15800037 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,13304603 0,15792243 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,13304603 0,15784455 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,13304603 0,15776676 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,13304603 0,15768904 ! muscle cell development GO:0055001 49 32 0,000 0,13304603 0,1576114 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,13304603 0,15753384 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,13304603 0,15745635 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,13304603 0,15737894 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,13304603 0,1573016 ! ovulation cycle GO:0042698 51 32 0,000 0,13304603 0,15722434 ! peripheral nervous system development GO:0007422 64 32 0,000 0,13304603 0,15714716 ! BMP signaling pathway GO:0030509 64 32 0,000 0,13304603 0,15707005 ! hindbrain development GO:0030902 61 32 0,000 0,13304603 0,15699301 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,13304603 0,15691606 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,13304603 0,15683918 ! gene silencing GO:0016458 65 32 0,000 0,13304603 0,15676237 ! post-embryonic development GO:0009791 69 33 0,000 0,13690749 0,16123319 ! protein targeting to membrane GO:0006612 68 33 0,000 0,13690749 0,16115431 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,13690749 0,16107551 ! formation of primary germ layer GO:0001704 72 33 0,000 0,13690749 0,16099678 ! cell fate specification GO:0001708 52 33 0,000 0,13690749 0,16091813 ! sterol transport GO:0015918 57 33 0,000 0,13690749 0,16083956 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,13690749 0,16076106 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,13690749 0,16068264 ! adult locomotory behavior GO:0008344 59 33 0,000 0,13690749 0,1606043 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,13690749 0,16052603 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,14075187 0,16495324 ! glial cell differentiation GO:0010001 63 34 0,000 0,14075187 0,16487293 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,14075187 0,1647927 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,14075187 0,16471255 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,14075187 0,16463247 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,14075187 0,16455248 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,14075187 0,16447256 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,14075187 0,16439272 ! mismatch repair GO:0006298 46 34 0,000 0,14075187 0,16431295 ! spermatid development GO:0007286 63 34 0,000 0,14075187 0,16423327 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,14075187 0,16415366 ! placenta development GO:0001890 53 34 0,000 0,14075187 0,16407413 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 0,000 0,14075187 0,16399467 ! regulation of muscle development GO:0048634 70 35 0,000 0,14457926 0,16837255 ! negative regulation of secretion GO:0051048 63 35 0,000 0,14457926 0,16829109 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,14457926 0,16820971 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,14457926 0,16812841 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,14457926 0,16804719 ! female gonad development GO:0008585 58 35 0,000 0,14457926 0,16796605 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,14457926 0,16788498 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,14457926 0,167804 ! cytokine production GO:0001816 59 35 0,000 0,14457926 0,16772309 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,14457926 0,16764226 ! neural tube formation GO:0001841 67 35 0,000 0,14457926 0,16756151 ! vesicle localization GO:0051648 64 35 0,000 0,14457926 0,16748083 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,14838972 0,17181216 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,14838972 0,17172952 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,14838972 0,17164695 ! cell junction organization GO:0034330 86 36 0,000 0,14838972 0,17156447 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,14838972 0,17148207 ! positive regulation of cell development GO:0010720 80 36 0,000 0,14838972 0,17139974 ! regulation of proteolysis GO:0030162 72 36 0,000 0,14838972 0,1713175 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,14838972 0,17123533 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,14838972 0,17115324 ! embryonic organ development GO:0048568 57 36 0,000 0,14838972 0,17107123 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,14838972 0,1709893 ! negative regulation of cell activation GO:0050866 65 36 0,000 0,14838972 0,17090745 ! RNA export from nucleus GO:0006405 56 37 0,000 0,15218334 0,17519287 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,15218334 0,17510909 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,15218334 0,17502539 ! actomyosin structure organization GO:0031032 62 37 0,000 0,15218334 0,17494176 ! organic anion transport GO:0015711 68 37 0,000 0,15218334 0,17485822 ! tissue remodeling GO:0048771 76 37 0,000 0,15218334 0,17477475 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,15218334 0,17469137 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,15218334 0,17460806 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,15218334 0,17452484 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,15218334 0,17444169 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,15218334 0,17435862 ! pigment metabolic process GO:0042440 80 37 0,000 0,15218334 0,17427563 ! spermatid differentiation GO:0048515 66 37 0,000 0,15218334 0,17419272 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,15596018 0,1784309 GO:0006956|complement activation, ! positive regulation of DNA metabolic process GO:0051054 72 38 0,000 0,15596018 0,1783461 ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,15596018 0,17826137 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,15596018 0,17817673 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,15596018 0,17809216 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,15596018 0,17800768 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,15596018 0,17792328 ! lipid homeostasis GO:0055088 67 38 0,000 0,15596018 0,17783895 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,15596018 0,17775471 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,15596018 0,17767054 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,15596018 0,17758646 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,15596018 0,17750246 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,15596018 0,17741853 ! glucan metabolic process GO:0044042 62 38 0,000 0,15596018 0,17733468 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,15972032 0,18152437 ! mammary gland development GO:0030879 86 39 0,000 0,15972032 0,18143867 ! ear morphogenesis GO:0042471 60 39 0,000 0,15972032 0,18135304 ! organic ether metabolic process GO:0018904 55 39 0,000 0,15972032 0,1812675 ! ion transmembrane transport GO:0034220 66 39 0,000 0,15972032 0,18118203 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,15972032 0,18109665 ! regulation of action potential in neuron GO:0019228 73 39 0,000 0,15972032 0,18101135 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,15972032 0,18092613 ! RNA modification GO:0009451 57 39 0,000 0,15972032 0,18084099 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,15972032 0,18075592 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,16346384 0,1849055 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,16346384 0,18481861 ! feeding behavior GO:0007631 59 40 0,000 0,16346384 0,1847318 ! negative regulation of binding GO:0051100 72 40 0,000 0,16346384 0,18464507 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,16346384 0,18455842 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,16346384 0,18447185 ! maintenance of protein location GO:0045185 91 40 0,000 0,16346384 0,18438537 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,1671908 0,18850097 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,1671908 0,18841268 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,1671908 0,18832447 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,1671908 0,18823634 ! gliogenesis GO:0042063 88 41 0,000 0,1671908 0,1881483 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,1671908 0,18806034 ! regulation of T cell proliferation GO:0042129 71 41 0,000 0,1671908 0,18797246 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,1671908 0,18788466 ! regulation of T cell differentiation GO:0045580 70 41 0,000 0,1671908 0,18779695 ! female gamete generation GO:0007292 61 41 0,000 0,1671908 0,18770932 ! polyol metabolic process GO:0019751 66 41 0,000 0,1671908 0,18762177 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,1671908 0,1875343 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,17090128 0,19160694 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,17090128 0,19151769 ! regulation of tube size GO:0035150 71 42 0,000 0,17090128 0,19142853 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,17090128 0,19133945 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,17090128 0,19125046 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,17090128 0,19116154 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,17090128 0,19107272 ! regulation of protein secretion GO:0050708 71 42 0,000 0,17090128 0,19098397 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,17090128 0,1908953 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,17459535 0,19493105 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,17459535 0,19484064 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,17459535 0,19475031 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,17459535 0,19466007 ! glucose transport GO:0015758 65 43 0,000 0,17459535 0,1945699 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,17459535 0,19447982 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,17459535 0,19438983 ! neural tube development GO:0021915 77 43 0,000 0,17459535 0,19429992 ! striated muscle contraction GO:0006941 77 43 0,000 0,17459535 0,19421009 ! phagocytosis GO:0006909 90 43 0,000 0,17459535 0,19412034 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,17459535 0,19403068 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,17827309 0,19802634 ! hexose transport GO:0008645 67 44 0,000 0,17827309 0,19793496 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,17827309 0,19784366 ! biopolymer methylation GO:0043414 84 44 0,000 0,17827309 0,19775245 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,17827309 0,19766131 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,17827309 0,19757027 ! developmental growth GO:0048589 82 44 0,000 0,17827309 0,19747931 ! maintenance of location in cell GO:0051651 97 44 0,000 0,17827309 0,19738843 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,18193456 0,20134984 ! glycolysis GO:0006096 65 45 0,000 0,18193456 0,20125727 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,18193456 0,20116478 ! leukocyte migration GO:0050900 68 45 0,000 0,18193456 0,20107237 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,18193456 0,20098005 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,18193456 0,20088782 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,18193456 0,20079567 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,18193456 0,2007036 ! icosanoid metabolic process GO:0006690 80 45 0,000 0,18193456 0,20061162 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,18193456 0,20051972 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,18557984 0,20444372 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,18557984 0,20435015 ! pigmentation GO:0043473 100 46 0,000 0,18557984 0,20425667 ! positive regulation of defense response GO:0031349 76 47 0,000 0,18920899 0,20815585 ! endosome transport GO:0016197 108 47 0,000 0,18920899 0,20806071 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,18920899 0,20796566 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,18920899 0,2078707 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,18920899 0,20777583 ! JNK cascade GO:0007254 91 47 0,000 0,18920899 0,20768104 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,18920899 0,20758634 ! methylation GO:0032259 90 47 0,000 0,18920899 0,20749172 ! Notch signaling pathway GO:0007219 96 48 0,000 0,19282209 0,21135761 ! cellular component disassembly GO:0022411 86 48 0,000 0,19282209 0,21126137 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,19282209 0,21116521 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,19282209 0,21106913 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,19282209 0,21097315 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,19282209 0,21087725 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,19282209 0,21078144 ! regulation of lymphocyte differentiation GO:0045619 81 48 0,000 0,19282209 0,21068572 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,19641922 0,21451867 ! regulation of action potential GO:0001508 95 49 0,000 0,19641922 0,21442134 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,19641922 0,2143241 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,19641922 0,21422694 ! regulation of ion transport GO:0043269 77 49 0,000 0,19641922 0,21412987 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,19641922 0,2140329 ! peptide metabolic process GO:0006518 76 49 0,000 0,19641922 0,213936 ! response to temperature stimulus GO:0009266 76 49 0,000 0,19641922 0,2138392 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,19641922 0,21374248 ! endocrine system development GO:0035270 104 49 0,000 0,19641922 0,21364586 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,19641922 0,21354931 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,19641922 0,21345286 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,19641922 0,21335649 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,19641922 0,21326021 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,20000043 0,21705053 ! neuromuscular process GO:0050905 99 50 0,000 0,20000043 0,21695267 ! regulation of ossification GO:0030278 117 50 0,000 0,20000043 0,2168549 ! inner ear development GO:0048839 79 50 0,000 0,20000043 0,21675722 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,20000043 0,21665962 ! negative regulation of immune system process GO:0002683 95 50 0,000 0,20000043 0,21656212 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,20000043 0,2164647 ! viral infectious cycle GO:0019058 99 51 0,000 0,20356579 0,22022451 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,20356579 0,22012553 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,20356579 0,22002664 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,20356579 0,21992784 ! excretion GO:0007588 83 51 0,000 0,20356579 0,21982913 ! chromatin remodeling GO:0006338 109 51 0,000 0,20356579 0,21973051 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,20356579 0,21963197 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,20356579 0,21953353 ! vesicle organization GO:0016050 107 51 0,000 0,20356579 0,21943517 ! regulation of cell shape GO:0008360 125 51 0,000 0,20356579 0,2193369 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,20356579 0,21923872 ! regulation of angiogenesis GO:0045765 114 52 0,000 0,20711539 0,2229618 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,20711539 0,22286209 ! membrane fusion GO:0006944 110 52 0,000 0,20711539 0,22276246 ! positive regulation of growth GO:0045927 90 52 0,000 0,20711539 0,22266293 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,20711539 0,22256348 ! amino acid activation GO:0043038 92 52 0,000 0,20711539 0,22246412 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! cartilage development GO:0051216 90 52 0,000 0,20711539 0,22236485 ! synapse organization GO:0050808 85 52 0,000 0,20711539 0,22226567 ! RNA catabolic process GO:0006401 93 53 0,000 0,21064929 0,22595728 ! regulation of translational initiation GO:0006446 82 53 0,000 0,21064929 0,22585659 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,21064929 0,22575598 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,21064929 0,22565547 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,21064929 0,22555504 ! cell maturation GO:0048469 100 53 0,000 0,21064929 0,22545471 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,21064929 0,22535446 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,21416755 0,2290165 ! cell recognition GO:0008037 85 54 0,000 0,21416755 0,22891476 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,21416755 0,22881311 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,21416755 0,22871155 ! chloride transport GO:0006821 90 55 0,000 0,21767024 0,23234898 ! glucose catabolic process GO:0006007 82 55 0,000 0,21767024 0,23224594 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,21767024 0,232143 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,21767024 0,23204014 ! gastrulation GO:0007369 112 55 0,000 0,21767024 0,23193738 ! heart morphogenesis GO:0003007 97 55 0,000 0,21767024 0,23183471 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,21767024 0,23173213 ! nuclear export GO:0051168 97 55 0,000 0,21767024 0,23162963 ! regulation of actin filament length GO:0030832 105 56 0,000 0,22115744 0,23523643 ! sensory perception of smell GO:0007608 80 56 0,000 0,22115744 0,23513248 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,22115744 0,23502862 ! proton transport GO:0015992 94 56 0,000 0,22115744 0,23492486 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,22462921 0,23850745 ! maintenance of location GO:0051235 118 57 0,000 0,22462921 0,23840224 ! hydrogen transport GO:0006818 97 58 0,000 0,22808562 0,24196385 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,22808562 0,24185721 ! regulation of endocytosis GO:0030100 91 58 0,000 0,22808562 0,24175066 ! adult behavior GO:0030534 99 58 0,000 0,22808562 0,24164421 ! regulation of cellular component size GO:0032535 109 59 0,000 0,23152674 0,24518193 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,23152674 0,24507406 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,23152674 0,24496629 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,23152674 0,24485861 ! DNA catabolic process GO:0006308 86 59 0,000 0,23152674 0,24475103 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,23152674 0,24464354 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,23495263 0,24815453 ! regulation of heart contraction GO:0008016 110 60 0,000 0,23495263 0,24804565 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,23495263 0,24793685 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,23836336 0,2514258 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,23836336 0,25131562 ! mesoderm development GO:0007498 119 61 0,000 0,23836336 0,25120554 ! tRNA processing GO:0008033 89 61 0,000 0,23836336 0,25109555 ! ear development GO:0043583 103 62 0,000 0,241759 0,25456112 ! viral reproductive process GO:0022415 126 62 0,000 0,241759 0,25444976 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,241759 0,2543385 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,241759 0,25422734 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,24513961 0,25766968 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,24513961 0,25755716 ! detection of external stimulus GO:0009581 91 63 0,000 0,24513961 0,25744474 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,24513961 0,25733242 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,24850526 0,26075171 ! cell redox homeostasis GO:0045454 102 64 0,000 0,24850526 0,26063804 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,24850526 0,26052447 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,24850526 0,260411 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,24850526 0,26029763 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,25185602 0,2636926 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,25185602 0,2635779 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,25185602 0,2634633 GO:0035113|embryonic appendage morphogenesis, ! myeloid cell differentiation GO:0030099 111 65 0,000 0,25185602 0,2633488 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,25519195 0,26672104 ! actin filament organization GO:0007015 148 66 0,000 0,25519195 0,26660522 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,25519195 0,26648951 ! extracellular matrix organization GO:0030198 133 66 0,000 0,25519195 0,26637389 ! secondary metabolic process GO:0019748 116 66 0,000 0,25519195 0,26625838 ! developmental maturation GO:0021700 116 66 0,000 0,25519195 0,26614297 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,25851311 0,26948984 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,25851311 0,26937312 ! activation of MAPK activity GO:0000187 115 67 0,000 0,25851311 0,26925651 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,25851311 0,26914 ! hexose catabolic process GO:0019320 104 67 0,000 0,25851311 0,26902359 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,25851311 0,26890728 ! adaptive immune response GO:0002250 119 67 0,000 0,25851311 0,26879107 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,25851311 0,26867497 ! amino acid transport GO:0006865 125 68 0,000 0,26181957 0,27199391 ! viral reproduction GO:0016032 134 68 0,000 0,26181957 0,27187652 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,26181957 0,27175923 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,2651114 0,27505737 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,2651114 0,27493881 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,2651114 0,27482035 ! antigen processing and presentation GO:0019882 104 69 0,000 0,2651114 0,274702 ! appendage morphogenesis GO:0035107 135 70 0,000 0,26838866 0,2779781 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 0,000 0,27165142 0,28123636 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,27165142 0,2811154 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,27165142 0,28099454 ! regulation of immune effector process GO:0002697 137 71 0,000 0,27165142 0,28087379 ! acute inflammatory response GO:0002526 113 72 0,000 0,27489972 0,28411028 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,27489972 0,28398829 ! carbohydrate transport GO:0008643 110 72 0,000 0,27489972 0,28386641 ! regulation of blood pressure GO:0008217 125 73 0,000 0,27813366 0,28708261 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,27813366 0,28695951 ! axon guidance GO:0007411 139 73 0,000 0,27813366 0,28683651 ! fertilization GO:0009566 90 73 0,000 0,27813366 0,28671361 ! transition metal ion transport GO:0000041 126 74 0,000 0,28135327 0,28990834 ! exocytosis GO:0006887 133 74 0,000 0,28135327 0,28978423 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,28135327 0,28966023 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,28135327 0,28953634 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,28455863 0,29270973 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,28455863 0,29258464 ! phosphoinositide-mediated signaling GO:0048015 131 75 0,000 0,28455863 0,29245966 ! rhythmic process GO:0048511 128 75 0,000 0,28455863 0,29233478 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,2877498 0,29548699 ! defense response to bacterium GO:0042742 89 76 0,000 0,2877498 0,29536093 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,2877498 0,29523498 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,2877498 0,29510913 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,29092684 0,2982403 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,29092684 0,29811328 ! blood coagulation GO:0007596 146 78 0,000 0,29408982 0,3012261 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,29408982 0,30109792 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,29723879 0,30419248 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,29723879 0,30406315 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,29723879 0,30393393 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,29723879 0,30380481 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,30037382 0,30687873 ! inorganic anion transport GO:0015698 138 80 0,000 0,30037382 0,30674848 ! digestion GO:0007586 112 81 0,000 0,30349497 0,30980437 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,30349497 0,30967298 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,30349497 0,30954171 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,30349497 0,30941055 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,30660229 0,31244605 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,30660229 0,31231377 ! response to nutrient GO:0007584 125 82 0,000 0,30660229 0,3121816 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,30660229 0,31204954 ! regulation of lyase activity GO:0051339 160 83 0,000 0,30969586 0,3150648 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,31277573 0,31806357 ! hemostasis GO:0007599 158 84 0,000 0,31277573 0,3179292 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,31277573 0,31779494 ! response to unfolded protein GO:0006986 131 85 0,000 0,31584196 0,32077491 ! nucleosome assembly GO:0006334 122 85 0,000 0,31584196 0,32063956 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,31584196 0,32050432 ! chromatin assembly GO:0031497 124 86 0,000 0,31889461 0,32346561 ! tube morphogenesis GO:0035239 176 86 0,000 0,31889461 0,3233293 ! amine transport GO:0015837 155 86 0,000 0,31889461 0,3231931 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,32193374 0,32613582 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,32495941 0,32906243 ! regulation of neurological system process GO:0031644 148 88 0,000 0,32495941 0,328924 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,32495941 0,32878568 ! cellular defense response GO:0006968 114 89 0,000 0,32797168 0,33169393 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,32797168 0,33155456 ! regulation of cell adhesion GO:0030155 212 89 0,000 0,32797168 0,33141531 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,33097061 0,33430532 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,33097061 0,33416503 ! sterol metabolic process GO:0016125 152 91 0,000 0,33395625 0,33703806 ! response to protein stimulus GO:0051789 149 91 0,000 0,33395625 0,33689675 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,33395625 0,33675555 ! regulation of defense response GO:0031347 149 92 0,000 0,33692867 0,33961055 ! nucleosome organization GO:0034728 138 92 0,000 0,33692867 0,33946833 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,33692867 0,33932624 ! vitamin metabolic process GO:0006766 139 92 0,000 0,33692867 0,33918426 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,33988792 0,34202022 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,33988792 0,34187723 ! regulation of membrane potential GO:0042391 164 93 0,000 0,33988792 0,34173437 ! negative regulation of multicellular organismal process GO:0051241 166 93 0,000 0,33988792 0,34159162 ! female pregnancy GO:0007565 164 94 0,000 0,34283407 0,34440867 ! regulation of T cell activation GO:0050863 158 94 0,000 0,34283407 0,34426493 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,34868726 0,34999647 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,34868726 0,34985052 ! positive regulation of immune response GO:0050778 156 96 0,000 0,34868726 0,34970469 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,35159442 0,3524734 ! hormone metabolic process GO:0042445 157 97 0,000 0,35159442 0,3523266 ! response to virus GO:0009615 160 98 0,000 0,3544887 0,35507902 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,3544887 0,35493126 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,3544887 0,35478362 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,35737016 0,35751875 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,35737016 0,35737016