pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6435-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! induction of positive chemotaxis GO:0050930 14 8 3,000 1,06E-08 2,439E-05 ! regulation of positive chemotaxis GO:0050926 17 11 3,000 4,958E-08 5,702E-05 GO:0050927|positive regulation of positive chemotaxis, ! protein amino acid autophosphorylation GO:0046777 80 45 4,000 5,653E-07 4,334E-04 ! positive regulation of locomotion GO:0040017 35 20 3,000 7,104E-07 4,085E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 36 21 3,000 8,752E-07 4,026E-04 ! regulation of behavior GO:0050795 38 22 3,000 1,067E-06 4,089E-04 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 3,000 1,541E-06 5,064E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 2,000 1,545E-06 4,442E-04 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 2,466E-06 6,301E-04 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 2,000 3,689E-06 8,485E-04 ! chondrocyte differentiation GO:0002062 17 11 2,000 7,209E-06 1,507E-03 ! negative regulation of glucose import GO:0046325 14 11 2,000 7,209E-06 1,382E-03 GO:0010829|negative regulation of glucose transport, ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 2,000 1,243E-05 2,2E-03 ! positive regulation of response to external stimulus GO:0032103 65 40 3,000 1,27E-05 2,086E-03 ! regulation of the force of heart contraction GO:0002026 21 15 2,000 1,968E-05 3,017E-03 ! response to UV GO:0009411 75 46 3,000 2,231E-05 3,206E-03 ! neutrophil chemotaxis GO:0030593 21 16 2,000 2,416E-05 3,268E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 2,000 2,926E-05 3,738E-03 ! inactivation of MAPK activity GO:0000188 27 17 2,000 2,926E-05 3,541E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 2,926E-05 3,364E-03 ! positive regulation of cell migration GO:0030335 92 51 3,000 3,37E-05 3,691E-03 ! regulation of glucose import GO:0046324 21 18 2,000 3,502E-05 3,661E-03 GO:0010827|regulation of glucose transport, ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 4,148E-05 4,148E-03 ! positive regulation of intracellular transport GO:0032388 29 19 2,000 4,148E-05 3,975E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 4,867E-05 4,478E-03 ! positive regulation of inflammatory response GO:0050729 30 20 2,000 4,867E-05 4,305E-03 ! positive regulation of cell motion GO:0051272 99 56 3,000 4,887E-05 4,163E-03 ! negative regulation of protein kinase activity GO:0006469 99 57 3,000 5,242E-05 4,306E-03 ! negative regulation of kinase activity GO:0033673 100 58 3,000 5,615E-05 4,453E-03 ! negative regulation of transferase activity GO:0051348 105 61 3,000 6,851E-05 5,252E-03 ! negative regulation of phosphorylation GO:0042326 41 23 2,000 7,503E-05 5,567E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 3,000 7,778E-05 5,59E-03 ! insulin receptor signaling pathway GO:0008286 40 24 2,000 8,553E-05 5,961E-03 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 2,000 9,694E-05 6,558E-03 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of protein modification process GO:0031400 50 26 2,000 1,093E-04 7,183E-03 ! positive regulation of phosphorylation GO:0042327 102 70 3,000 1,175E-04 7,506E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,269E-04 7,89E-03 ! apoptotic cell clearance GO:0043277 13 5 1,000 1,269E-04 7,682E-03 ! positive regulation of glycolysis GO:0045821 11 5 1,000 1,269E-04 7,485E-03 ! early endosome to late endosome transport GO:0045022 11 5 1,000 1,269E-04 7,298E-03 ! regulation of respiratory burst GO:0060263 8 5 1,000 1,269E-04 7,12E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 1,269E-04 6,951E-03 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 3,000 1,311E-04 7,013E-03 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of MAP kinase activity GO:0043407 54 28 2,000 1,37E-04 7,162E-03 ! negative regulation of transport GO:0051051 116 73 3,000 1,383E-04 7,071E-03 ! cellular response to hormone stimulus GO:0032870 109 74 3,000 1,459E-04 7,293E-03 ! leukocyte chemotaxis GO:0030595 43 31 2,000 1,866E-04 9,129E-03 GO:0060326|cell chemotaxis, ! regulation of protein export from nucleus GO:0046825 6 6 1,000 1,899E-04 9,101E-03 ! mRNA stabilization GO:0048255 15 6 1,000 1,899E-04 8,916E-03 GO:0043489|RNA stabilization, ! ER overload response GO:0006983 7 6 1,000 1,899E-04 8,737E-03 ! male sex determination GO:0030238 9 6 1,000 1,899E-04 8,566E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 1,000 1,899E-04 8,401E-03 ! cellular response to insulin stimulus GO:0032869 52 34 2,000 2,464E-04 0,01069467 ! positive regulation of MAP kinase activity GO:0043406 121 85 3,000 2,492E-04 0,01061306 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 2,653E-04 0,01109441 ! microtubule bundle formation GO:0001578 8 7 1,000 2,653E-04 0,01089629 ! T-helper 1 type immune response GO:0042088 11 7 1,000 2,653E-04 0,01070513 ! protein heterooligomerization GO:0051291 10 7 1,000 2,653E-04 0,01052056 ! regulation of intracellular protein transport GO:0033157 59 35 2,000 2,689E-04 0,0104808 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 3,529E-04 0,01352832 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 3,529E-04 0,01330655 ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 3,529E-04 0,01309193 ! regulation of vascular permeability GO:0043114 12 8 1,000 3,529E-04 0,01288412 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 1,000 3,529E-04 0,0126828 ! induction of an organ GO:0001759 11 8 1,000 3,529E-04 0,01248768 ! regulation of embryonic development GO:0045995 16 8 1,000 3,529E-04 0,01229848 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 3,529E-04 0,01211492 ! regulation of epithelial cell proliferation GO:0050678 71 39 2,000 3,716E-04 0,01256804 ! regulation of response to external stimulus GO:0032101 139 96 3,000 3,969E-04 0,01322997 ! response to light stimulus GO:0009416 153 96 3,000 3,969E-04 0,01304097 ! induction of apoptosis by intracellular signals GO:0008629 67 40 2,000 4,007E-04 0,01297963 ! positive regulation of protein transport GO:0051222 55 40 2,000 4,007E-04 0,01279935 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 3,000 4,461E-04 0,0140567 ! regulation of developmental growth GO:0048638 13 9 1,000 4,527E-04 0,01407012 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 4,527E-04 0,01388252 ! regulation of glycolysis GO:0006110 15 9 1,000 4,527E-04 0,01369986 ! lung alveolus development GO:0048286 17 9 1,000 4,527E-04 0,01352194 ! receptor clustering GO:0043113 15 9 1,000 4,527E-04 0,01334858 ! motor axon guidance GO:0008045 14 9 1,000 4,527E-04 0,01317961 ! postreplication repair GO:0006301 11 9 1,000 4,527E-04 0,01301486 ! localization within membrane GO:0051668 15 9 1,000 4,527E-04 0,01285419 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 2,000 4,632E-04 0,01299162 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 4,966E-04 0,01376238 ! leukocyte migration GO:0050900 60 43 2,000 4,966E-04 0,01359855 ! response to insulin stimulus GO:0032868 63 43 2,000 4,966E-04 0,01343856 ! induction of apoptosis by extracellular signals GO:0008624 74 44 2,000 5,316E-04 0,01421767 ! regulation of inflammatory response GO:0050727 60 44 2,000 5,316E-04 0,01405425 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 5,645E-04 0,01475527 ! blood vessel remodeling GO:0001974 21 10 1,000 5,645E-04 0,01458948 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 5,645E-04 0,01442738 ! regulation of bone resorption GO:0045124 24 10 1,000 5,645E-04 0,01426883 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 5,645E-04 0,01411374 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 5,645E-04 0,01396198 GO:0043470|regulation of carbohydrate catabolic process, ! developmental induction GO:0031128 13 10 1,000 5,645E-04 0,01381345 GO:0045168|cell-cell signaling involved in cell fate specification, ! cytoplasmic sequestering of protein GO:0051220 14 10 1,000 5,645E-04 0,01366804 ! positive regulation of defense response GO:0031349 59 45 2,000 5,681E-04 0,01361148 ! regulation of muscle contraction GO:0006937 69 48 2,000 6,872E-04 0,01629401 ! virus-host interaction GO:0019048 17 11 1,000 6,884E-04 0,01615639 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 6,884E-04 0,0159932 ! dopamine receptor signaling pathway GO:0007212 22 11 1,000 6,884E-04 0,01583327 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 6,884E-04 0,0156765 ! actin cytoskeleton reorganization GO:0031532 21 11 1,000 6,884E-04 0,01552281 ! regulation of leukocyte migration GO:0002685 24 11 1,000 6,884E-04 0,0153721 ! negative regulation of mast cell proliferation GO:0070667 17 11 1,000 6,884E-04 0,01522429 GO:0042130|negative regulation of T cell proliferation, ! regulation of intracellular transport GO:0032386 78 49 2,000 7,301E-04 0,01599321 ! cartilage development GO:0051216 70 49 2,000 7,301E-04 0,01584233 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 8,242E-04 0,01771572 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 8,242E-04 0,01755168 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of mRNA stability GO:0043488 27 12 1,000 8,242E-04 0,01739066 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 8,242E-04 0,01723256 ! positive regulation of protein import into nucleus GO:0042307 23 13 1,000 9,718E-04 0,02013544 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 9,718E-04 0,01995566 ! regulation of RNA stability GO:0043487 28 13 1,000 9,718E-04 0,01977906 ! negative regulation of response to stimulus GO:0048585 80 56 2,000 1,079E-03 0,0217692 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 1,131E-03 0,02262165 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 1,131E-03 0,02242664 ! negative regulation of microtubule depolymerization GO:0007026 31 14 1,000 1,131E-03 0,02223496 GO:0031114|regulation of microtubule depolymerization, ! response to peptide hormone stimulus GO:0043434 84 57 2,000 1,136E-03 0,02214291 ! lung development GO:0030324 94 59 2,000 1,256E-03 0,02427033 ! positive regulation of cell size GO:0045793 20 15 1,000 1,302E-03 0,02495631 ! lipid phosphorylation GO:0046834 23 15 1,000 1,302E-03 0,02475005 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 1,302E-03 0,02454719 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 1,302E-03 0,02434761 ! negative regulation of leukocyte proliferation GO:0070664 25 15 1,000 1,302E-03 0,02415126 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 1,000 1,302E-03 0,02395805 ! regulation of heart contraction GO:0008016 91 60 2,000 1,318E-03 0,02406674 ! respiratory tube development GO:0030323 99 62 2,000 1,45E-03 0,02625447 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 1,485E-03 0,02667689 ! mitotic chromosome condensation GO:0007076 25 16 1,000 1,485E-03 0,0264701 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 1,485E-03 0,02626648 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 2,000 1,589E-03 0,02789674 ! respiratory system development GO:0060541 100 64 2,000 1,589E-03 0,0276854 ! signal complex assembly GO:0007172 29 17 1,000 1,679E-03 0,02902975 ! neuromuscular junction development GO:0007528 23 17 1,000 1,679E-03 0,02881311 ! negative regulation of protein catabolic process GO:0042177 26 17 1,000 1,679E-03 0,02859968 ! peptidyl-serine modification GO:0018209 27 17 1,000 1,679E-03 0,02838938 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 1,679E-03 0,02818216 ! positive regulation of DNA replication GO:0045740 29 18 1,000 1,884E-03 0,03140224 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 1,000 1,884E-03 0,03117632 ! positive regulation of translation GO:0045727 28 18 1,000 1,884E-03 0,03095363 ! negative regulation of T cell activation GO:0050868 25 18 1,000 1,884E-03 0,0307341 ! regulation of catabolic process GO:0009894 106 70 2,000 2,056E-03 0,03329804 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 2,101E-03 0,03379098 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 2,101E-03 0,03355632 GO:0010675|regulation of cellular carbohydrate metabolic process, ! sex determination GO:0007530 29 19 1,000 2,101E-03 0,0333249 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 2,101E-03 0,03309665 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 2,101E-03 0,0328715 ! protein stabilization GO:0050821 26 19 1,000 2,101E-03 0,03264939 ! chromosome condensation GO:0030261 31 20 1,000 2,329E-03 0,03595016 ! gluconeogenesis GO:0006094 25 21 1,000 2,568E-03 0,03937808 ! dendrite development GO:0016358 35 21 1,000 2,568E-03 0,0391173 ! activation of pro-apoptotic gene products GO:0008633 36 21 1,000 2,568E-03 0,03885995 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 2,568E-03 0,03860596 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 1,000 2,568E-03 0,03835527 ! regulation of protein transport GO:0051223 114 76 2,000 2,6E-03 0,03858068 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein modification process GO:0031401 107 78 2,000 2,799E-03 0,04127165 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 2,818E-03 0,04128878 ! vasculogenesis GO:0001570 33 22 1,000 2,818E-03 0,04102746 ! protein tetramerization GO:0051262 39 22 1,000 2,818E-03 0,04076943 ! regulation of transcription factor import into nucleus GO:0042990 46 23 1,000 3,08E-03 0,04427044 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 3,08E-03 0,04399547 ! interaction with host GO:0051701 37 23 1,000 3,08E-03 0,04372389 ! negative regulation of catabolic process GO:0009895 34 23 1,000 3,08E-03 0,04345564 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 3,08E-03 0,04319067 ! myelination GO:0042552 35 23 1,000 3,08E-03 0,04292891 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 3,08E-03 0,0426703 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 3,352E-03 0,0461636 ! pyruvate metabolic process GO:0006090 29 24 1,000 3,352E-03 0,04588882 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 3,352E-03 0,04561729 ! receptor metabolic process GO:0043112 37 24 1,000 3,352E-03 0,04534895 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 3,352E-03 0,04508375 ! regulation of defense response GO:0031347 117 84 2,000 3,453E-03 0,04617124 ! regulation of protein localization GO:0032880 132 85 2,000 3,57E-03 0,04746259 ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 3,635E-03 0,04804776 ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 3,635E-03 0,0477732 ! interphase of mitotic cell cycle GO:0051329 156 86 2,000 3,69E-03 0,04821673 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 3,929E-03 0,05105114 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 3,929E-03 0,05076434 ! circadian rhythm GO:0007623 42 26 1,000 3,929E-03 0,05048074 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 3,929E-03 0,05020029 ! interphase GO:0051325 159 88 2,000 3,936E-03 0,05001741 ! negative regulation of leukocyte activation GO:0002695 39 27 1,000 4,233E-03 0,05349654 ! negative regulation of transcription regulator activity GO:0090048 47 27 1,000 4,233E-03 0,05320421 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of protein transport GO:0051224 49 27 1,000 4,233E-03 0,05291505 ! ensheathment of neurons GO:0007272 43 28 1,000 4,548E-03 0,05654638 GO:0008366|axon ensheathment, ! positive regulation of catabolic process GO:0009896 40 28 1,000 4,548E-03 0,05624237 ! peptidyl-amino acid modification GO:0018193 147 93 2,000 4,596E-03 0,0565245 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 4,874E-03 0,05962769 ! hexose biosynthetic process GO:0019319 35 29 1,000 4,874E-03 0,0593122 ! regulation of microtubule-based process GO:0032886 58 30 1,000 5,21E-03 0,06306825 ! negative regulation of cell activation GO:0050866 44 30 1,000 5,21E-03 0,06273805 ! mammary gland development GO:0030879 57 31 1,000 5,556E-03 0,06656139 ! maintenance of protein location in cell GO:0032507 60 31 1,000 5,556E-03 0,06621652 ! cell fate specification GO:0001708 37 31 1,000 5,556E-03 0,06587519 ! mitotic sister chromatid segregation GO:0000070 45 32 1,000 5,913E-03 0,06974508 ! peripheral nervous system development GO:0007422 53 32 1,000 5,913E-03 0,06938924 ! regulation of protein stability GO:0031647 48 32 1,000 5,913E-03 0,06903701 ! calcium-mediated signaling GO:0019722 50 32 1,000 5,913E-03 0,06868834 ! monosaccharide biosynthetic process GO:0046364 38 32 1,000 5,913E-03 0,06834317 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 5,913E-03 0,06800145 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 1,000 6,28E-03 0,07186219 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 6,28E-03 0,07150644 ! sister chromatid segregation GO:0000819 46 33 1,000 6,28E-03 0,07115419 ! carbohydrate homeostasis GO:0033500 39 33 1,000 6,28E-03 0,0708054 GO:0042593|glucose homeostasis, ! negative regulation of DNA binding GO:0043392 54 33 1,000 6,28E-03 0,07046 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 6,657E-03 0,07432837 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 1,000 6,657E-03 0,07396929 ! regulation of action potential in neuron GO:0019228 54 35 1,000 7,044E-03 0,07789493 ! maintenance of protein location GO:0045185 65 35 1,000 7,044E-03 0,07752223 ! glycogen metabolic process GO:0005977 48 35 1,000 7,044E-03 0,07715307 ! negative regulation of binding GO:0051100 58 36 1,000 7,442E-03 0,08111674 ! tissue remodeling GO:0048771 62 36 1,000 7,442E-03 0,08073412 ! hormone-mediated signaling GO:0009755 49 36 1,000 7,442E-03 0,08035508 ! glucan metabolic process GO:0044042 49 36 1,000 7,442E-03 0,07997959 GO:0006073|cellular glucan metabolic process, ! alcohol biosynthetic process GO:0046165 45 38 1,000 8,266E-03 0,0884227 ! regulation of T cell proliferation GO:0042129 58 38 1,000 8,266E-03 0,08801334 ! phagocytosis GO:0006909 60 38 1,000 8,266E-03 0,08760775 ! maintenance of location in cell GO:0051651 69 38 1,000 8,266E-03 0,08720588 ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 8,692E-03 0,09128904 ! JNK cascade GO:0007254 54 39 1,000 8,692E-03 0,09087409 ! cell growth GO:0016049 61 39 1,000 8,692E-03 0,0904629 ! synapse organization GO:0050808 55 39 1,000 8,692E-03 0,09005541 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 1,000 9,129E-03 0,09415257 ! peptide metabolic process GO:0006518 56 40 1,000 9,129E-03 0,09373225 ! energy reserve metabolic process GO:0006112 59 41 1,000 9,575E-03 0,09787504 ! endosome transport GO:0016197 71 41 1,000 9,575E-03 0,09744196 ! regulation of T cell differentiation GO:0045580 59 41 1,000 9,575E-03 0,0970127 ! regulation of JNK cascade GO:0046328 58 41 1,000 9,575E-03 0,09658721 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 1,000 0,01003031 0,1007411 ! regulation of cell shape GO:0008360 78 42 1,000 0,01003031 0,10030309 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 0,01049537 0,10449932 ! regulation of action potential GO:0001508 71 44 1,000 0,01096983 0,10875263 ! regulation of mast cell proliferation GO:0070666 64 44 1,000 0,01096983 0,10828588 ! positive regulation of cell cycle GO:0045787 77 45 1,000 0,01145363 0,11257842 ! vascular process in circulatory system GO:0003018 69 45 1,000 0,01145363 0,11209936 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 0,0119467 0,11642965 ! negative regulation of immune system process GO:0002683 73 47 1,000 0,01244895 0,12081263 ! regulation of leukocyte proliferation GO:0070663 71 47 1,000 0,01244895 0,12030501 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 0,01296033 0,12472288 ! heart morphogenesis GO:0003007 65 48 1,000 0,01296033 0,12420321 ! regulation of DNA replication GO:0006275 75 48 1,000 0,01296033 0,12368784 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 0,01296033 0,12317673 ! regulation of angiogenesis GO:0045765 94 49 1,000 0,01348077 0,12759576 ! maintenance of location GO:0051235 84 49 1,000 0,01348077 0,12707282 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,01401019 0,1315242 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 0,01401019 0,13098955 ! lipid modification GO:0030258 73 50 1,000 0,01401019 0,13045923 ! positive regulation of growth GO:0045927 67 50 1,000 0,01401019 0,12993318 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 1,000 0,01454852 0,13438391 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,01454852 0,13384637 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 0,01454852 0,13331312 ! regulation of protein catabolic process GO:0042176 77 51 1,000 0,01454852 0,1327841 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,0150957 0,1372336 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,01565165 0,14172753 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,01621631 0,14626476 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,01621631 0,14569342 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,01621631 0,14512652 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01789117 0,15949489 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01789117 0,15887908 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01789117 0,158268 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01789117 0,15766161 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01789117 0,15705985 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01789117 0,15646267 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01789117 0,15587 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01789117 0,15528182 ! sleep GO:0030431 11 5 0,000 0,01789117 0,15469805 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01789117 0,15411866 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01789117 0,15354359 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01789117 0,15297279 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01789117 0,15240623 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,01789117 0,15184384 ! tongue development GO:0043586 6 5 0,000 0,01789117 0,15128559 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01789117 0,15073143 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01789117 0,15018132 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01789117 0,1496352 ! cobalt ion transport GO:0006824 9 5 0,000 0,01789117 0,14909305 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01789117 0,14855481 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01789117 0,14802044 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01789117 0,1474899 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01789117 0,14696315 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01789117 0,14644015 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,01789117 0,14592085 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01789117 0,14540523 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01789117 0,14489324 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01789117 0,14438485 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01789117 0,14388 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01789117 0,14337868 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01789117 0,14288084 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 0,000 0,01789117 0,14238644 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01789117 0,14189545 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01789117 0,14140784 ! malate metabolic process GO:0006108 7 5 0,000 0,01789117 0,14092357 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01789117 0,1404426 ! behavioral response to pain GO:0048266 7 5 0,000 0,01789117 0,1399649 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01789117 0,13949044 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01789117 0,13901919 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01789117 0,13855111 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,01789117 0,13808618 ! mating behavior GO:0007617 6 5 0,000 0,01789117 0,13762435 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01789117 0,1371656 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01789117 0,1367099 ! rhythmic behavior GO:0007622 12 5 0,000 0,01789117 0,13625722 ! copulation GO:0007620 7 5 0,000 0,01789117 0,13580753 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01789117 0,13536079 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01789117 0,13491699 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01789117 0,13447608 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01789117 0,13403805 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01789117 0,13360286 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01789117 0,13317049 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01789117 0,13274091 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01789117 0,13231409 ! response to protozoan GO:0001562 9 5 0,000 0,01789117 0,13189 ! lymph vessel development GO:0001945 7 5 0,000 0,01789117 0,13146863 ! endochondral ossification GO:0001958 12 5 0,000 0,01789117 0,13104994 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01789117 0,13063391 ! parathyroid gland development GO:0060017 8 5 0,000 0,01789117 0,13022051 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01789117 0,12980972 ! anagen GO:0042640 6 5 0,000 0,01789117 0,12940151 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01789117 0,12899587 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01789117 0,12859275 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01789117 0,12819215 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01789117 0,12779404 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01789117 0,12739839 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01789117 0,12700519 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01789117 0,1266144 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01789117 0,12622602 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01789117 0,12584 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01789117 0,12545634 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01789117 0,12507502 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01789117 0,124696 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,01789117 0,12431928 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01789117 0,12394482 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01789117 0,12357262 ! ovulation GO:0030728 6 5 0,000 0,01789117 0,12320264 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01789117 0,12283487 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,01789117 0,12246929 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,01789117 0,12210588 ! response to pH GO:0009268 9 5 0,000 0,01789117 0,12174462 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01789117 0,12138549 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01789117 0,12102847 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01789117 0,12067355 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01789117 0,1203207 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01789117 0,11996992 ! polyol catabolic process GO:0046174 7 5 0,000 0,01789117 0,11962117 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01789117 0,11927444 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01789117 0,11892971 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01789117 0,11858698 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01789117 0,11824621 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01789117 0,1179074 ! urea metabolic process GO:0019627 6 5 0,000 0,01789117 0,11757052 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01789117 0,11723556 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01789117 0,1169025 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01789117 0,11657133 ! neutrophil activation GO:0042119 5 5 0,000 0,01789117 0,11624204 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01789117 0,11591459 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01789117 0,11558899 ! response to food GO:0032094 5 5 0,000 0,01789117 0,11526521 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01789117 0,11494324 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01789117 0,11462307 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01789117 0,11430467 ! forebrain neuron development GO:0021884 7 5 0,000 0,01789117 0,11398804 ! melanosome organization GO:0032438 7 5 0,000 0,01789117 0,11367315 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01789117 0,11336 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01789117 0,11304857 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01789117 0,11273885 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01789117 0,11243082 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01789117 0,11212447 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01789117 0,11181979 ! nucleoside transport GO:0015858 6 5 0,000 0,01789117 0,11151675 ! nucleoside salvage GO:0043174 7 5 0,000 0,01789117 0,11121535 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01789117 0,11091558 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01789117 0,11061742 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01789117 0,11032086 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01789117 0,11002589 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01789117 0,10973248 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01789117 0,10944064 ! depyrimidination GO:0045008 8 5 0,000 0,01789117 0,10915035 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01789117 0,10886159 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01789117 0,10857436 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01789117 0,10828863 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01789117 0,10800441 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01789117 0,10772168 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01789117 0,10744042 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01789117 0,10716063 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01789117 0,10688229 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01789117 0,10660539 ! monocyte differentiation GO:0030224 8 5 0,000 0,01789117 0,10632993 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01789117 0,10605588 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01789117 0,10578324 ! centrosome duplication GO:0051298 5 5 0,000 0,01789117 0,105512 ! response to UV-C GO:0010225 6 5 0,000 0,01789117 0,10524215 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01789117 0,10497368 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01789117 0,10470657 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01789117 0,10444081 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01789117 0,10417641 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01789117 0,10391334 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01789117 0,10365159 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01789117 0,10339116 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01789117 0,10313203 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01789117 0,1028742 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01789117 0,10261766 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01789117 0,10236239 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,01789117 0,10210839 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01789117 0,10185565 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01789117 0,10160415 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01789117 0,10135389 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01789117 0,10110487 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01789117 0,10085706 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01789117 0,10061047 ! neural tube patterning GO:0021532 6 5 0,000 0,01789117 0,10036508 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01789117 0,10012088 ! histone demethylation GO:0016577 9 5 0,000 0,01789117 0,09987787 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01789117 0,09963603 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01789117 0,09939536 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01789117 0,09915586 ! enteric nervous system development GO:0048484 8 5 0,000 0,01789117 0,0989175 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01789117 0,09868029 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01789117 0,09844421 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01789117 0,09820926 ! transcription termination GO:0006353 8 5 0,000 0,01789117 0,09797543 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01789117 0,09774271 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01789117 0,09751109 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01789117 0,09728057 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01789117 0,09705113 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01789117 0,09682278 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01789117 0,0965955 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01789117 0,09636928 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01789117 0,09614411 ! apical protein localization GO:0045176 6 5 0,000 0,01789117 0,09592 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,01789117 0,09569693 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01789117 0,0954749 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01789117 0,09525389 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01789117 0,09503391 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01789117 0,09481493 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01789117 0,09459697 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01789117 0,09438 ! glial cell migration GO:0008347 10 5 0,000 0,01789117 0,09416403 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01789117 0,09394904 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01789117 0,09373504 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,01789117 0,093522 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01789117 0,09330993 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01789117 0,09309883 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01789117 0,09288867 ! neural plate development GO:0001840 6 5 0,000 0,01789117 0,09267946 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01789117 0,09247119 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01789117 0,09226386 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01789117 0,09205745 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01789117 0,09185197 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01789117 0,0916474 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01789117 0,09144374 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01789117 0,09124098 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01789117 0,09103912 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01789117 0,09083815 ! spindle assembly GO:0051225 5 5 0,000 0,01789117 0,09063806 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,01789117 0,09043886 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01789117 0,09024053 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01789117 0,09004307 ! organ regeneration GO:0031100 7 5 0,000 0,01789117 0,08984647 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01789117 0,08965072 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01789117 0,08945583 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,01789117 0,08926178 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01789117 0,08906857 GO:0055081|anion homeostasis, ! chromosome segregation GO:0007059 83 57 1,000 0,01796187 0,08922742 ! viral reproductive process GO:0022415 87 58 1,000 0,01856069 0,0920034 ! activation of MAPK activity GO:0000187 84 59 1,000 0,01916788 0,09480886 ! actin filament organization GO:0007015 95 59 1,000 0,01916788 0,09460541 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 1,000 0,01978338 0,09743419 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,01978338 0,09722599 ! regulation of homeostatic process GO:0032844 105 60 1,000 0,01978338 0,09701869 ! regulation of cellular response to stress GO:0080135 85 61 1,000 0,02040711 0,0998646 ! cell-matrix adhesion GO:0007160 114 61 1,000 0,02040711 0,09965258 ! tRNA transcription GO:0009304 11 6 0,000 0,02143141 0,10443272 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,02143141 0,10421193 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,02143141 0,10399208 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,02143141 0,10377314 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02143141 0,10355513 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,02143141 0,10333804 ! regulation of helicase activity GO:0051095 11 6 0,000 0,02143141 0,10312185 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,02143141 0,10290656 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,02143141 0,10269217 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,02143141 0,10247868 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,02143141 0,10226607 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,02143141 0,10205434 ! prostate gland development GO:0030850 9 6 0,000 0,02143141 0,10184348 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,02143141 0,10163349 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,02143141 0,10142437 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,02143141 0,10121611 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,02143141 0,1010087 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,02143141 0,10080213 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,02143141 0,10059642 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,02143141 0,10039154 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,02143141 0,10018749 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,02143141 0,09998427 ! neuron adhesion GO:0007158 9 6 0,000 0,02143141 0,09978187 ! N-terminal protein amino acid acetylation GO:0006474 7 6 0,000 0,02143141 0,09958029 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,02143141 0,09937952 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,02143141 0,09917957 ! signal peptide processing GO:0006465 8 6 0,000 0,02143141 0,09898041 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,02143141 0,09878205 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,02143141 0,09858449 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,02143141 0,09838771 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,02143141 0,09819172 ! opsonization GO:0008228 8 6 0,000 0,02143141 0,09799651 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,02143141 0,09780207 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,02143141 0,0976084 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,02143141 0,0974155 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,02143141 0,09722336 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,02143141 0,09703198 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02143141 0,09684134 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,02143141 0,09665146 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,02143141 0,09646232 ! mechanosensory behavior GO:0007638 8 6 0,000 0,02143141 0,09627391 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,02143141 0,09608625 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,02143141 0,09589931 ! response to interferon-gamma GO:0034341 12 6 0,000 0,02143141 0,09571309 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,02143141 0,0955276 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,02143141 0,09534283 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02143141 0,09515877 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,02143141 0,09497542 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,02143141 0,09479278 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,02143141 0,09461083 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,02143141 0,09442959 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,02143141 0,09424903 ! thymic T cell selection GO:0045061 12 6 0,000 0,02143141 0,09406917 ! protein lipoylation GO:0009249 10 6 0,000 0,02143141 0,09388999 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,02143141 0,09371149 ! pigment granule organization GO:0048753 11 6 0,000 0,02143141 0,09353367 ! drug transport GO:0015893 6 6 0,000 0,02143141 0,09335652 ! cysteine metabolic process GO:0006534 7 6 0,000 0,02143141 0,09318005 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,02143141 0,09300423 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,02143141 0,09282908 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02143141 0,09265459 ! histidine metabolic process GO:0006547 6 6 0,000 0,02143141 0,09248076 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,02143141 0,09230757 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,02143141 0,09213504 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,02143141 0,09196314 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,02143141 0,09179189 ! adenohypophysis development GO:0021984 10 6 0,000 0,02143141 0,09162127 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,02143141 0,09145129 ! hyperosmotic response GO:0006972 8 6 0,000 0,02143141 0,09128193 ! microtubule nucleation GO:0007020 10 6 0,000 0,02143141 0,0911132 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,02143141 0,0909451 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,02143141 0,09077761 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,02143141 0,09061074 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,02143141 0,09044448 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,02143141 0,09027883 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,02143141 0,09011379 ! response to dietary excess GO:0002021 7 6 0,000 0,02143141 0,08994935 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,02143141 0,08978551 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,02143141 0,08962226 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,02143141 0,08945961 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,02143141 0,08929754 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,02143141 0,08913606 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,02143141 0,08897517 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02143141 0,08881485 ! neuron apoptosis GO:0051402 8 6 0,000 0,02143141 0,08865511 ! organic alcohol transport GO:0015850 9 6 0,000 0,02143141 0,08849595 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,02143141 0,08833735 ! T cell mediated immunity GO:0002456 12 6 0,000 0,02143141 0,08817933 ! carnitine transport GO:0015879 8 6 0,000 0,02143141 0,08802186 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,02143141 0,08786496 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,02143141 0,08770862 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02143141 0,08755283 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,02143141 0,0873976 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,02143141 0,08724291 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,02143141 0,08708877 ! parturition GO:0007567 12 6 0,000 0,02143141 0,08693517 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,02143141 0,08678212 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,02143141 0,0866296 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,02143141 0,08647762 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,02143141 0,08632617 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,02143141 0,08617525 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,02143141 0,08602486 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,02143141 0,08587499 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,02143141 0,08572564 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,02143141 0,08557681 ! macrophage differentiation GO:0030225 10 6 0,000 0,02143141 0,0854285 ! astrocyte development GO:0014002 14 6 0,000 0,02143141 0,0852807 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,02143141 0,08513341 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,02143141 0,08498663 ! interaction with symbiont GO:0051702 8 6 0,000 0,02143141 0,08484035 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,02143141 0,08469458 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02143141 0,0845493 ! eating behavior GO:0042755 6 6 0,000 0,02143141 0,08440453 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,02143141 0,08426025 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,02143141 0,08411646 ! response to copper ion GO:0046688 9 6 0,000 0,02143141 0,08397316 ! DNA topological change GO:0006265 8 6 0,000 0,02143141 0,08383035 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,02143141 0,08368802 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,02143141 0,08354618 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,02143141 0,08340481 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02143141 0,08326393 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02143141 0,08312351 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,02143141 0,08298358 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,02143141 0,08284411 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,02143141 0,08270511 ! gas homeostasis GO:0033483 11 6 0,000 0,02143141 0,08256657 ! hair follicle maturation GO:0048820 7 6 0,000 0,02143141 0,0824285 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,02143141 0,08229089 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,02143141 0,08215374 ! Schwann cell development GO:0014044 14 6 0,000 0,02143141 0,08201704 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,02143141 0,0818808 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,02143141 0,08174501 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02143141 0,08160968 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,02143141 0,08147478 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,02143141 0,08134034 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,02143141 0,08120633 ! histone ubiquitination GO:0016574 7 6 0,000 0,02143141 0,08107277 ! regulation of meiosis GO:0040020 10 6 0,000 0,02143141 0,08093965 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,02143141 0,08080696 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,02143141 0,0806747 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,02143141 0,08054288 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,02143141 0,08041149 ! membrane to membrane docking GO:0022614 12 6 0,000 0,02143141 0,08028053 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,02143141 0,08014999 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,02143141 0,08001988 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,02143141 0,07989018 ! receptor internalization GO:0031623 9 6 0,000 0,02143141 0,07976091 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,02143141 0,07963206 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,02143141 0,07950362 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02143141 0,07937559 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,02143141 0,07924798 ! protein deubiquitination GO:0016579 8 6 0,000 0,02143141 0,07912078 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,02143141 0,07899398 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,02143141 0,07886759 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,02143141 0,0787416 ! axonal fasciculation GO:0007413 9 6 0,000 0,02143141 0,07861602 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,02143141 0,07849083 ! thiamin metabolic process GO:0006772 6 6 0,000 0,02143141 0,07836605 ! midbrain development GO:0030901 6 6 0,000 0,02143141 0,07824166 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,02143141 0,07811766 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02143141 0,07799406 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,02143141 0,07787084 ! progesterone metabolic process GO:0042448 8 6 0,000 0,02143141 0,07774802 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,02143141 0,07762558 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,02143141 0,07750353 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,02143141 0,07738186 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,02143141 0,07726057 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,02143141 0,07713966 ! adult feeding behavior GO:0008343 6 6 0,000 0,02143141 0,07701913 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,02143141 0,07689898 ! blastocyst growth GO:0001832 15 6 0,000 0,02143141 0,0767792 ! pigment granule transport GO:0051904 12 6 0,000 0,02143141 0,07665979 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,02143141 0,07654075 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,02143141 0,07642208 ! catecholamine transport GO:0051937 7 6 0,000 0,02143141 0,07630378 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02143141 0,07618585 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,02143141 0,07606828 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,02143141 0,07595107 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,02143141 0,07583422 ! protein prenylation GO:0018342 10 6 0,000 0,02143141 0,07571773 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02143141 0,0756016 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,02143141 0,07548583 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,02143141 0,0753704 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,02143141 0,07525533 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,02167905 0,07600887 GO:0090046|regulation of transcription regulator activity, ! cAMP-mediated signaling GO:0019933 97 63 1,000 0,02167905 0,07589318 ! viral reproduction GO:0016032 92 63 1,000 0,02167905 0,07577784 ! regulation of lipase activity GO:0060191 109 63 1,000 0,02167905 0,07566285 ! adaptive immune response GO:0002250 94 64 1,000 0,02232712 0,07780664 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 0,02298317 0,0799717 ! protein oligomerization GO:0051259 100 65 1,000 0,02298317 0,0798509 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,02364714 0,08203382 ! axon guidance GO:0007411 99 66 1,000 0,02364714 0,08191027 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,0249591 0,08632469 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,0249591 0,08619507 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,0249591 0,08606585 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,0249591 0,085937 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,0249591 0,08580855 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0249591 0,08568048 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,0249591 0,08555279 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0249591 0,08542547 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,0249591 0,08529854 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,0249591 0,08517199 ! reproductive behavior GO:0019098 12 7 0,000 0,0249591 0,08504581 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,0249591 0,08492 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,0249591 0,08479456 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,0249591 0,0846695 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,0249591 0,0845448 ! oligopeptide transport GO:0006857 11 7 0,000 0,0249591 0,08442047 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,0249591 0,0842965 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,0249591 0,0841729 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,0249591 0,08404966 ! RNA methylation GO:0001510 11 7 0,000 0,0249591 0,08392678 ! pericardium development GO:0060039 8 7 0,000 0,0249591 0,08380426 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,0249591 0,0836821 ! fibril organization GO:0043206 13 7 0,000 0,0249591 0,08356029 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,0249591 0,08343884 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0249591 0,08331773 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,0249591 0,08319698 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,0249591 0,08307658 ! lipoprotein transport GO:0042953 9 7 0,000 0,0249591 0,08295653 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,0249591 0,08283682 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0249591 0,08271746 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0249591 0,08259844 ! estrogen metabolic process GO:0008210 14 7 0,000 0,0249591 0,08247977 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,0249591 0,08236143 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,0249591 0,08224344 ! chemosensory behavior GO:0007635 9 7 0,000 0,0249591 0,08212578 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,0249591 0,08200846 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,0249591 0,08189147 ! leukocyte degranulation GO:0043299 10 7 0,000 0,0249591 0,08177481 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,0249591 0,08165849 ! reflex GO:0060004 12 7 0,000 0,0249591 0,0815425 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0249591 0,08142684 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,0249591 0,0813115 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,0249591 0,08119649 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,0249591 0,08108181 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,0249591 0,08096745 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0249591 0,08085341 ! spinal cord patterning GO:0021511 7 7 0,000 0,0249591 0,08073969 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,0249591 0,08062629 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,0249591 0,08051321 ! adrenal gland development GO:0030325 17 7 0,000 0,0249591 0,08040045 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,0249591 0,080288 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,0249591 0,08017586 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,0249591 0,08006404 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,0249591 0,07995253 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,0249591 0,07984133 ! endosome organization GO:0007032 10 7 0,000 0,0249591 0,07973044 ! thyroid hormone generation GO:0006590 11 7 0,000 0,0249591 0,07961986 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,0249591 0,07950958 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,0249591 0,07939961 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,0249591 0,07928994 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0249591 0,07918058 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,0249591 0,07907151 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0249591 0,07896275 ! galactose metabolic process GO:0006012 10 7 0,000 0,0249591 0,07885428 ! vesicle fusion GO:0006906 15 7 0,000 0,0249591 0,07874612 ! intracellular pH reduction GO:0051452 10 7 0,000 0,0249591 0,07863825 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,0249591 0,07853067 ! organ growth GO:0035265 11 7 0,000 0,0249591 0,07842339 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,0249591 0,0783164 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,0249591 0,0782097 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,0249591 0,07810329 ! retinol metabolic process GO:0042572 9 7 0,000 0,0249591 0,07799717 ! behavioral fear response GO:0001662 13 7 0,000 0,0249591 0,07789134 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,0249591 0,0777858 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,0249591 0,07768054 ! rRNA modification GO:0000154 12 7 0,000 0,0249591 0,07757557 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0249591 0,07747088 ! response to UV-B GO:0010224 11 7 0,000 0,0249591 0,07736647 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,0249591 0,07726234 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,0249591 0,07715849 ! intermediate filament organization GO:0045109 11 7 0,000 0,0249591 0,07705492 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,0249591 0,07695163 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,0249591 0,07684862 ! fibrinolysis GO:0042730 9 7 0,000 0,0249591 0,07674588 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,0249591 0,07664342 ! B cell lineage commitment GO:0002326 17 7 0,000 0,0249591 0,07654123 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,0249591 0,07643931 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,0249591 0,07633766 ! response to tropane GO:0014073 13 7 0,000 0,0249591 0,07623628 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,0249591 0,07613517 ! melanosome localization GO:0032400 10 7 0,000 0,0249591 0,07603433 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,0249591 0,07593376 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,0249591 0,07583345 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,0249591 0,0757334 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,0249591 0,07563362 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,0249591 0,0755341 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,0249591 0,07543485 ! mast cell activation GO:0045576 9 7 0,000 0,0249591 0,07533585 ! multicellular organismal aging GO:0010259 11 7 0,000 0,0249591 0,07523712 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,0249591 0,07513864 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,0249591 0,07504042 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,0249591 0,07494245 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,0249591 0,07484474 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,0249591 0,07474729 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,0249591 0,07465009 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,0249591 0,07455314 ! T cell lineage commitment GO:0002360 12 7 0,000 0,0249591 0,07445644 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,0249591 0,07436 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,0249591 0,0742638 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,0249591 0,07416785 ! regulation of lipid transport GO:0032368 13 7 0,000 0,0249591 0,07407215 ! response to tumor cell GO:0002347 12 7 0,000 0,0249591 0,0739767 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,0249591 0,07388149 ! neuroblast proliferation GO:0007405 13 7 0,000 0,0249591 0,07378653 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,0249591 0,07369181 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,0249591 0,07359733 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,0249591 0,0735031 ! diuresis GO:0030146 12 7 0,000 0,0249591 0,0734091 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,0249591 0,07331535 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,0249591 0,07322184 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0249591 0,07312856 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,0249591 0,07303552 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,0249591 0,07294272 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0249591 0,07285015 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0249591 0,07275782 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,0249591 0,07266572 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,0249591 0,07257385 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,0249591 0,07248222 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,0249591 0,07239082 ! lymph node development GO:0048535 9 7 0,000 0,0249591 0,07229965 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,0249591 0,0722087 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,0249591 0,07211799 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0249591 0,0720275 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,0249591 0,07193724 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,0249591 0,07184721 ! ATP catabolic process GO:0006200 10 7 0,000 0,0249591 0,0717574 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,0249591 0,07166781 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,0249591 0,07157845 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,0249591 0,07148931 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,0249591 0,0714004 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,0249591 0,0713117 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,0249591 0,07122322 ! muscle adaptation GO:0043500 12 7 0,000 0,0249591 0,07113497 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,0249591 0,07104693 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,0249591 0,07095911 ! retina homeostasis GO:0001895 9 7 0,000 0,0249591 0,07087151 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,0249591 0,07078412 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,0249591 0,07069694 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,0249591 0,07060999 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,0249591 0,07052324 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,0249591 0,07043671 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,0249591 0,07035039 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0249591 0,07026428 ! rhythmic process GO:0048511 105 68 1,000 0,02499857 0,07028939 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,02708352 0,07605873 ! response to hypoxia GO:0001666 132 72 1,000 0,02779367 0,07795785 ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,02779367 0,07786289 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,02847426 0,07967252 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,02847426 0,07957571 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,02847426 0,07947914 ! axon extension GO:0048675 11 8 0,000 0,02847426 0,0793828 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,02847426 0,07928669 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,02847426 0,07919082 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,02847426 0,07909518 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,02847426 0,07899977 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,02847426 0,07890459 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,02847426 0,07880964 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,02847426 0,07871491 ! phosphate transport GO:0006817 10 8 0,000 0,02847426 0,07862042 ! N-glycan processing GO:0006491 12 8 0,000 0,02847426 0,07852615 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,02847426 0,0784321 ! UTP metabolic process GO:0046051 8 8 0,000 0,02847426 0,07833829 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,02847426 0,07824469 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,02847426 0,07815132 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,02847426 0,07805817 ! succinate metabolic process GO:0006105 14 8 0,000 0,02847426 0,07796525 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,02847426 0,07787254 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02847426 0,07778006 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,02847426 0,07768779 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,02847426 0,07759574 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,02847426 0,07750391 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,02847426 0,0774123 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,02847426 0,07732091 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02847426 0,07722973 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,02847426 0,07713876 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,02847426 0,07704801 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,02847426 0,07695747 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,02847426 0,07686715 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,02847426 0,07677703 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,02847426 0,07668713 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,02847426 0,07659744 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,02847426 0,07650795 ! astrocyte differentiation GO:0048708 16 8 0,000 0,02847426 0,07641868 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,02847426 0,07632961 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,02847426 0,07624075 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,02847426 0,0761521 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,02847426 0,07606366 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,02847426 0,07597541 ! melanin metabolic process GO:0006582 12 8 0,000 0,02847426 0,07588738 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,02847426 0,07579955 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02847426 0,07571192 ! macrophage activation GO:0042116 12 8 0,000 0,02847426 0,07562449 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,02847426 0,07553726 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,02847426 0,07545024 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,02847426 0,07536341 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,02847426 0,07527679 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,02847426 0,07519036 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,02847426 0,07510414 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,02847426 0,07501811 ! ruffle organization GO:0031529 11 8 0,000 0,02847426 0,07493227 ! osteoblast development GO:0002076 13 8 0,000 0,02847426 0,07484664 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,02847426 0,0747612 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,02847426 0,07467595 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,02847426 0,0745909 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,02847426 0,07450604 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,02847426 0,07442137 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,02847426 0,0743369 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,02847426 0,07425262 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,02847426 0,07416853 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,02847426 0,07408462 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,02847426 0,07400091 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,02847426 0,07391739 ! oligodendrocyte development GO:0014003 8 8 0,000 0,02847426 0,07383406 ! segment specification GO:0007379 10 8 0,000 0,02847426 0,07375091 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,02847426 0,07366795 ! cellular extravasation GO:0045123 11 8 0,000 0,02847426 0,07358518 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,02847426 0,07350259 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,02847426 0,07342019 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,02847426 0,07333797 ! snRNA metabolic process GO:0016073 10 8 0,000 0,02847426 0,07325594 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,02847426 0,07317409 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,02847426 0,07309242 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,02847426 0,07301093 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,02847426 0,07292963 ! nucleosome disassembly GO:0006337 12 8 0,000 0,02847426 0,07284851 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,02847426 0,07276756 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,02847426 0,0726868 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,02847426 0,07260622 ! icosanoid secretion GO:0032309 12 8 0,000 0,02847426 0,07252581 GO:0050482|arachidonic acid secretion, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02847426 0,07244558 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,02847426 0,07236553 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,02847426 0,07228566 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,02847426 0,07220596 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,02847426 0,07212644 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,02847426 0,07204709 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,02847426 0,07196792 ! sterol catabolic process GO:0016127 9 8 0,000 0,02847426 0,07188892 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,02847426 0,0718101 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,02847426 0,07173144 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,02847426 0,07165296 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,02847426 0,07157465 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02847426 0,07149651 ! prophase GO:0051324 11 8 0,000 0,02847426 0,07141855 ! S phase GO:0051320 8 8 0,000 0,02847426 0,07134075 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,02847426 0,07126312 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,02847426 0,07118566 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,02847426 0,07110837 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,02847426 0,07103124 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,02847426 0,07095429 ! hormone catabolic process GO:0042447 13 8 0,000 0,02847426 0,0708775 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,02847426 0,07080087 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,02847426 0,07072441 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,02847426 0,07064812 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,02847426 0,07057199 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,02847426 0,07049603 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,02847426 0,07042022 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,02847426 0,07034458 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02847426 0,07026911 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,02847426 0,07019379 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,02847426 0,07011864 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,02847426 0,07004364 ! lamellipodium assembly GO:0030032 9 8 0,000 0,02847426 0,06996881 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02847426 0,06989414 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,02847426 0,06981962 ! response to oxygen levels GO:0070482 137 74 1,000 0,02923634 0,0716119 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,03070843 0,07513765 ! regulation of adenylate cyclase activity GO:0045761 131 77 1,000 0,03145536 0,07688346 ! regulation of DNA binding GO:0051101 119 77 1,000 0,03145536 0,07680184 ! gland development GO:0048732 148 77 1,000 0,03145536 0,0767204 ! carbohydrate biosynthetic process GO:0016051 97 77 1,000 0,03145536 0,07663912 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,03197696 0,07782752 ! telencephalon cell migration GO:0022029 16 9 0,000 0,03197696 0,07774525 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,03197696 0,07766316 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,03197696 0,07758123 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,03197696 0,07749948 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,03197696 0,07741791 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03197696 0,0773365 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,03197696 0,07725526 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,03197696 0,0771742 ! GTP metabolic process GO:0046039 9 9 0,000 0,03197696 0,0770933 ! elastic fiber assembly GO:0048251 13 9 0,000 0,03197696 0,07701258 ! social behavior GO:0035176 14 9 0,000 0,03197696 0,07693202 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,03197696 0,07685163 ! artery development GO:0060840 19 9 0,000 0,03197696 0,07677141 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,03197696 0,07669136 ! response to pain GO:0048265 16 9 0,000 0,03197696 0,07661147 ! protein complex disassembly GO:0043241 17 9 0,000 0,03197696 0,07653175 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,03197696 0,07645219 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,03197696 0,0763728 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,03197696 0,07629358 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,03197696 0,07621452 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,03197696 0,07613562 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,03197696 0,07605689 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,03197696 0,07597832 ! ventral spinal cord development GO:0021517 11 9 0,000 0,03197696 0,07589991 ! protein targeting to ER GO:0045047 19 9 0,000 0,03197696 0,07582166 ! T cell selection GO:0045058 18 9 0,000 0,03197696 0,07574357 ! endoderm development GO:0007492 12 9 0,000 0,03197696 0,07566565 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,03197696 0,07558788 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,03197696 0,07551028 ! arginine catabolic process GO:0006527 10 9 0,000 0,03197696 0,07543283 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,03197696 0,07535554 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,03197696 0,07527841 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,03197696 0,07520144 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03197696 0,07512463 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,03197696 0,07504797 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,03197696 0,07497147 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,03197696 0,07489512 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,03197696 0,07481893 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03197696 0,0747429 ! mannose metabolic process GO:0006013 9 9 0,000 0,03197696 0,07466702 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,03197696 0,07459129 ! epithelial cell development GO:0002064 10 9 0,000 0,03197696 0,07451571 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,03197696 0,07444029 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,03197696 0,07436503 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,03197696 0,07428991 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,03197696 0,07421494 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,03197696 0,07414013 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,03197696 0,07406547 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,03197696 0,07399096 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,03197696 0,07391659 ! blastoderm segmentation GO:0007350 11 9 0,000 0,03197696 0,07384238 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,03197696 0,07376831 ! DNA ligation GO:0006266 14 9 0,000 0,03197696 0,0736944 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,03197696 0,07362063 ! response to amine stimulus GO:0014075 13 9 0,000 0,03197696 0,07354701 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,03197696 0,07347354 ! erythrocyte development GO:0048821 11 9 0,000 0,03197696 0,07340021 ! renal water homeostasis GO:0003091 14 9 0,000 0,03197696 0,07332703 ! mRNA cleavage GO:0006379 13 9 0,000 0,03197696 0,07325399 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,03197696 0,0731811 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,03197696 0,07310836 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,03197696 0,07303576 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,03197696 0,0729633 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,03197696 0,07289099 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,03197696 0,07281882 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,03197696 0,0727468 ! acid secretion GO:0046717 14 9 0,000 0,03197696 0,07267491 ! musculoskeletal movement GO:0050881 11 9 0,000 0,03197696 0,07260317 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,03197696 0,07253157 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,03197696 0,07246011 ! purine base metabolic process GO:0006144 18 9 0,000 0,03197696 0,07238879 ! oocyte differentiation GO:0009994 12 9 0,000 0,03197696 0,07231761 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,03197696 0,07224657 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,03197696 0,07217567 ! spleen development GO:0048536 15 9 0,000 0,03197696 0,07210491 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,03197696 0,07203429 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,03197696 0,07196381 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,03197696 0,07189346 ! detection of calcium ion GO:0005513 13 9 0,000 0,03197696 0,07182325 ! blastocyst formation GO:0001825 12 9 0,000 0,03197696 0,07175318 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,03197696 0,07168325 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,03197696 0,07161345 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,03197696 0,07154378 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,03197696 0,07147426 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03197696 0,07140486 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,03197696 0,07133561 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,03197696 0,07126648 ! prepulse inhibition GO:0060134 14 9 0,000 0,03197696 0,07119749 ! embryonic placenta development GO:0001892 12 9 0,000 0,03197696 0,07112864 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,03197696 0,07105991 ! insulin secretion GO:0030073 17 9 0,000 0,03197696 0,07099132 ! sequestering of metal ion GO:0051238 11 9 0,000 0,03197696 0,07092286 ! response to nicotine GO:0035094 16 9 0,000 0,03197696 0,07085454 ! establishment of cell polarity GO:0030010 12 9 0,000 0,03197696 0,07078634 ! nucleus localization GO:0051647 15 9 0,000 0,03197696 0,07071828 ! regulation of synapse organization GO:0050807 12 9 0,000 0,03197696 0,07065035 ! regulation of cyclase activity GO:0031279 132 78 1,000 0,03220947 0,07109576 ! regulation of cAMP biosynthetic process GO:0030817 136 79 1,000 0,03297069 0,07270622 ! regulation of lyase activity GO:0051339 133 79 1,000 0,03297069 0,07263658 ! regulation of cAMP metabolic process GO:0030814 141 81 1,000 0,03451425 0,07596438 ! ossification GO:0001503 134 82 1,000 0,03529647 0,07761174 GO:0060348|bone development, ! negative regulation of muscle development GO:0048635 12 10 0,000 0,03546723 0,07791273 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,03546723 0,07783838 ! neuron fate specification GO:0048665 11 10 0,000 0,03546723 0,07776418 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,03546723 0,07769012 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,03546723 0,0776162 ! thyroid gland development GO:0030878 19 10 0,000 0,03546723 0,07754242 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,03546723 0,07746878 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,03546723 0,07739528 ! synapsis GO:0007129 13 10 0,000 0,03546723 0,07732192 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,03546723 0,0772487 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,03546723 0,07717562 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,03546723 0,07710267 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,03546723 0,07702986 ! sulfate transport GO:0008272 12 10 0,000 0,03546723 0,07695719 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,03546723 0,07688466 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,03546723 0,07681227 ! androgen metabolic process GO:0008209 13 10 0,000 0,03546723 0,07674001 ! phospholipid efflux GO:0033700 16 10 0,000 0,03546723 0,07666788 ! hippocampus development GO:0021766 19 10 0,000 0,03546723 0,07659589 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,03546723 0,07652404 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,03546723 0,07645232 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,03546723 0,07638074 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,03546723 0,07630929 ! pathogenesis GO:0009405 13 10 0,000 0,03546723 0,07623797 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,03546723 0,07616678 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03546723 0,07609573 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,03546723 0,07602481 ! peptide or protein amino-terminal blocking GO:0018409 14 10 0,000 0,03546723 0,07595403 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,03546723 0,07588337 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,03546723 0,07581285 ! melanocyte differentiation GO:0030318 15 10 0,000 0,03546723 0,07574246 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,03546723 0,07567219 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,03546723 0,07560206 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03546723 0,07553206 ! response to X-ray GO:0010165 16 10 0,000 0,03546723 0,07546219 ! B cell proliferation GO:0042100 14 10 0,000 0,03546723 0,07539245 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,03546723 0,07532283 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,03546723 0,07525335 ! forebrain cell migration GO:0021885 17 10 0,000 0,03546723 0,07518399 ! lipid digestion GO:0044241 15 10 0,000 0,03546723 0,07511476 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,03546723 0,07504565 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,03546723 0,07497668 ! UV protection GO:0009650 14 10 0,000 0,03546723 0,07490783 ! entry into host cell GO:0030260 20 10 0,000 0,03546723 0,07483911 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,03546723 0,07477051 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,03546723 0,07470204 ! negative regulation of ossification GO:0030279 19 10 0,000 0,03546723 0,07463369 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,03546723 0,07456547 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,03546723 0,07449738 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,03546723 0,0744294 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,03546723 0,07436156 ! regulation of organ growth GO:0046620 11 10 0,000 0,03546723 0,07429383 ! response to dsRNA GO:0043331 18 10 0,000 0,03546723 0,07422623 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,03546723 0,07415875 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03546723 0,0740914 ! embryonic axis specification GO:0000578 12 10 0,000 0,03546723 0,07402416 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,03546723 0,07395705 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,03546723 0,07389006 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,03546723 0,07382319 ! cranial nerve development GO:0021545 12 10 0,000 0,03546723 0,07375644 ! fucose catabolic process GO:0019317 16 10 0,000 0,03546723 0,07368982 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,03546723 0,07362331 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,03546723 0,07355692 ! protein sumoylation GO:0016925 12 10 0,000 0,03546723 0,07349065 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,03546723 0,07342451 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03546723 0,07335848 ! zymogen activation GO:0031638 14 10 0,000 0,03546723 0,07329257 ! salivary gland development GO:0007431 22 10 0,000 0,03546723 0,07322677 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03546723 0,0731611 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,03546723 0,07309554 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,03546723 0,0730301 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,03546723 0,07296478 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,03546723 0,07289958 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03546723 0,07283449 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,03546723 0,07276951 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,03546723 0,07270466 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,03546723 0,07263992 ! detection of bacterium GO:0016045 10 10 0,000 0,03546723 0,07257529 ! embryonic gut development GO:0048566 11 10 0,000 0,03546723 0,07251078 ! activation of innate immune response GO:0002218 10 10 0,000 0,03546723 0,07244638 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,03546723 0,0723821 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,03546723 0,07231793 ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,03546723 0,07225388 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,03546723 0,07218993 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,03546723 0,07212611 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 1,000 0,03608557 0,07331873 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of cell adhesion GO:0030155 159 83 1,000 0,03608557 0,07325402 ! microtubule cytoskeleton organization GO:0000226 120 84 1,000 0,03688149 0,07480372 ! regulation of DNA metabolic process GO:0051052 135 85 1,000 0,03768417 0,0763644 ! regulation of membrane potential GO:0042391 128 85 1,000 0,03768417 0,07629718 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,03768417 0,07623008 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 1,000 0,03849357 0,07779895 ! rRNA transcription GO:0009303 17 11 0,000 0,03894511 0,07864245 ! respiratory burst GO:0045730 14 11 0,000 0,03894511 0,07857347 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,03894511 0,07850461 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,03894511 0,07843586 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,03894511 0,07836724 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,03894511 0,07829874 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,03894511 0,07823035 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,03894511 0,07816209 ! RNA polyadenylation GO:0043631 19 11 0,000 0,03894511 0,07809395 ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,03894511 0,07802592 ! mating GO:0007618 14 11 0,000 0,03894511 0,07795801 ! T cell proliferation GO:0042098 20 11 0,000 0,03894511 0,07789022 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,03894511 0,07782255 ! bone resorption GO:0045453 16 11 0,000 0,03894511 0,077755 ! regulated secretory pathway GO:0045055 14 11 0,000 0,03894511 0,07768756 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,03894511 0,07762024 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,03894511 0,07755304 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,03894511 0,07748595 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,03894511 0,07741898 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,03894511 0,07735212 ! syncytium formation GO:0006949 15 11 0,000 0,03894511 0,07728538 ! plasma membrane organization GO:0007009 18 11 0,000 0,03894511 0,07721876 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,03894511 0,07715224 ! focal adhesion formation GO:0048041 24 11 0,000 0,03894511 0,07708585 ! mitotic spindle organization GO:0007052 15 11 0,000 0,03894511 0,07701957 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,03894511 0,0769534 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,03894511 0,07688734 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,03894511 0,0768214 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,03894511 0,07675558 ! adult heart development GO:0007512 11 11 0,000 0,03894511 0,07668986 ! temperature homeostasis GO:0001659 16 11 0,000 0,03894511 0,07662426 ! L-glutamate transport GO:0015813 16 11 0,000 0,03894511 0,07655877 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,03894511 0,07649339 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,03894511 0,07642812 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,03894511 0,07636296 ! stem cell development GO:0048864 29 11 0,000 0,03894511 0,07629792 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,03894511 0,07623298 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,03894511 0,07616816 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,03894511 0,07610345 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,03894511 0,07603884 ! vasoconstriction GO:0042310 15 11 0,000 0,03894511 0,07597435 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,03894511 0,07590996 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,03894511 0,07584569 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,03894511 0,07578152 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,03894511 0,07571746 ! ribosome assembly GO:0042255 13 11 0,000 0,03894511 0,07565351 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,03894511 0,07558967 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,03894511 0,07552593 ! chromatin silencing GO:0006342 19 11 0,000 0,03894511 0,07546231 ! nucleosome positioning GO:0016584 13 11 0,000 0,03894511 0,07539878 ! T cell homeostasis GO:0043029 20 11 0,000 0,03894511 0,07533537 ! regulation of isotype switching GO:0045191 19 11 0,000 0,03894511 0,07527206 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,03894511 0,07520886 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,03894511 0,07514577 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,03894511 0,07508278 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,03894511 0,0750199 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,03894511 0,07495712 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,03894511 0,07489444 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,03894511 0,07483188 ! male genitalia development GO:0030539 13 11 0,000 0,03894511 0,07476941 ! cholesterol efflux GO:0033344 19 11 0,000 0,03894511 0,07470705 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,03894511 0,0746448 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,03894511 0,07458264 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,03894511 0,0745206 ! germ cell migration GO:0008354 18 11 0,000 0,03894511 0,07445865 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,03894511 0,07439681 ! defense response to fungus GO:0050832 12 11 0,000 0,03894511 0,07433507 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,03894511 0,07427343 ! lysogeny GO:0030069 18 11 0,000 0,03894511 0,07421189 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,03894511 0,07415046 ! acrosome reaction GO:0007340 13 11 0,000 0,03894511 0,07408913 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,03894511 0,0740279 ! skeletal muscle tissue development GO:0007519 123 87 1,000 0,03930961 0,07465905 GO:0060538|skeletal muscle organ development, ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,03930961 0,07459745 ! reproductive developmental process GO:0003006 127 89 1,000 0,04096143 0,077668 ! regulation of nucleotide metabolic process GO:0006140 150 89 1,000 0,04096143 0,07760402 ! regulation of T cell activation GO:0050863 128 89 1,000 0,04096143 0,07754015 ! lactation GO:0007595 20 12 0,000 0,04241065 0,08021752 ! reproductive cellular process GO:0048610 14 12 0,000 0,04241065 0,0801516 ! tRNA modification GO:0006400 14 12 0,000 0,04241065 0,0800858 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,04241065 0,0800201 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,04241065 0,07995451 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,04241065 0,07988902 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,04241065 0,07982365 ! non-recombinational repair GO:0000726 19 12 0,000 0,04241065 0,07975838 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,04241065 0,07969322 ! peroxisomal transport GO:0043574 21 12 0,000 0,04241065 0,07962816 ! cartilage condensation GO:0001502 18 12 0,000 0,04241065 0,07956321 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,04241065 0,07949837 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,04241065 0,07943363 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,04241065 0,079369 ! heart looping GO:0001947 15 12 0,000 0,04241065 0,07930447 ! palate development GO:0060021 15 12 0,000 0,04241065 0,07924005 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,04241065 0,07917573 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,04241065 0,07911152 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,04241065 0,07904741 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,04241065 0,0789834 ! arginine metabolic process GO:0006525 13 12 0,000 0,04241065 0,0789195 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,04241065 0,0788557 ! methionine metabolic process GO:0006555 13 12 0,000 0,04241065 0,078792 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,04241065 0,07872841 ! Golgi organization GO:0007030 18 12 0,000 0,04241065 0,07866492 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,04241065 0,07860153 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,04241065 0,07853824 ! monoamine transport GO:0015844 13 12 0,000 0,04241065 0,07847506 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04241065 0,07841198 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,04241065 0,078349 ! L-amino acid transport GO:0015807 20 12 0,000 0,04241065 0,07828611 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,04241065 0,07822334 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,04241065 0,07816066 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,04241065 0,07809808 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04241065 0,0780356 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,04241065 0,07797322 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,04241065 0,07791094 ! cerebellum development GO:0021549 13 12 0,000 0,04241065 0,07784876 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,04241065 0,07778668 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,04241065 0,0777247 ! histone acetylation GO:0016573 23 12 0,000 0,04241065 0,07766282 ! histone methylation GO:0016571 15 12 0,000 0,04241065 0,07760103 ! autonomic nervous system development GO:0048483 23 12 0,000 0,04241065 0,07753935 ! gland morphogenesis GO:0022612 23 12 0,000 0,04241065 0,07747776 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,04241065 0,07741627 ! peptidyl-lysine modification GO:0018205 18 12 0,000 0,04241065 0,07735488 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,04241065 0,07729358 ! response to gamma radiation GO:0010332 20 12 0,000 0,04241065 0,07723238 ! regulation of epidermis development GO:0045682 17 12 0,000 0,04241065 0,07717128 ! intestinal absorption GO:0050892 19 12 0,000 0,04241065 0,07711028 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,04241065 0,07704937 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,04241065 0,07698856 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,04241065 0,07692784 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,04241065 0,07686722 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,04241065 0,07680669 ! microspike assembly GO:0030035 23 12 0,000 0,04241065 0,07674626 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,04241065 0,07668593 ! response to cold GO:0009409 14 12 0,000 0,04241065 0,07662569 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 1,000 0,04348762 0,07850983 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,04348762 0,07844825 ! cell fate commitment GO:0045165 141 92 1,000 0,04348762 0,07838677 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,04434239 0,07986491 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,04434239 0,07980242 ! N-terminal protein amino acid modification GO:0031365 18 13 0,000 0,04586389 0,08247612 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,04586389 0,08241168 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,04586389 0,08234735 ! cGMP metabolic process GO:0046068 16 13 0,000 0,04586389 0,08228312 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,04586389 0,08221898 ! water transport GO:0006833 17 13 0,000 0,04586389 0,08215495 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,04586389 0,08209102 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,04586389 0,08202718 ! lipid localization GO:0010876 24 13 0,000 0,04586389 0,08196345 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,04586389 0,08189981 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,04586389 0,08183627 ! organelle fusion GO:0048284 28 13 0,000 0,04586389 0,08177283 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,04586389 0,08170949 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,04586389 0,08164625 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,04586389 0,0815831 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,04586389 0,08152006 ! response to hexose stimulus GO:0009746 19 13 0,000 0,04586389 0,08145711 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,04586389 0,08139426 ! glutamate metabolic process GO:0006536 18 13 0,000 0,04586389 0,0813315 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,04586389 0,08126884 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,04586389 0,08120628 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,04586389 0,08114381 ! NAD metabolic process GO:0019674 21 13 0,000 0,04586389 0,08108144 ! exocrine system development GO:0035272 27 13 0,000 0,04586389 0,08101917 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,04586389 0,08095699 ! bone mineralization GO:0030282 15 13 0,000 0,04586389 0,0808949 ! regulation of exocytosis GO:0017157 17 13 0,000 0,04586389 0,08083292 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,04586389 0,08077102 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,04586389 0,08070922 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,04586389 0,08064752 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,04586389 0,08058591 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,04586389 0,08052439 ! genitalia development GO:0048806 15 13 0,000 0,04586389 0,08046297 ! regulation of cellular pH GO:0030641 20 13 0,000 0,04586389 0,08040164 ! cellular pigmentation GO:0033059 24 13 0,000 0,04586389 0,08034041 ! tissue regeneration GO:0042246 21 13 0,000 0,04586389 0,08027927 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,04586389 0,08021822 ! cofactor transport GO:0051181 19 13 0,000 0,04586389 0,08015726 ! NADP metabolic process GO:0006739 18 13 0,000 0,04586389 0,0800964 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,04586389 0,08003563 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,04586389 0,07997495 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04586389 0,07991436 ! gas transport GO:0015669 18 13 0,000 0,04586389 0,07985386 ! heme biosynthetic process GO:0006783 20 13 0,000 0,04586389 0,07979346 ! regulation of axon extension GO:0030516 23 13 0,000 0,04586389 0,07973315 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,04586389 0,07967293 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,04586389 0,0796128 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,04586389 0,07955276 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,04586389 0,07949281 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,04586389 0,07943295 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,04586389 0,07937318 ! regulation of binding GO:0051098 151 95 1,000 0,04607065 0,07967104 ! angiogenesis GO:0001525 149 95 1,000 0,04607065 0,07961119 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 1,000 0,04782351 0,08257814 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,04930488 0,08507218 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,04930488 0,08500841 ! superoxide anion generation GO:0042554 18 14 0,000 0,04930488 0,08494473 ! neuron maturation GO:0042551 21 14 0,000 0,04930488 0,08488115 ! regulation of S phase GO:0033261 18 14 0,000 0,04930488 0,08481767 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,04930488 0,08475428 ! myotube differentiation GO:0014902 21 14 0,000 0,04930488 0,08469098 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,04930488 0,08462778 ! inositol metabolic process GO:0006020 20 14 0,000 0,04930488 0,08456467 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,04930488 0,08450166 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,04930488 0,08443874 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,04930488 0,08437591 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,04930488 0,08431318 ! gene silencing by RNA GO:0031047 20 14 0,000 0,04930488 0,08425054 ! response to cAMP GO:0051591 19 14 0,000 0,04930488 0,08418799 ! limbic system development GO:0021761 25 14 0,000 0,04930488 0,08412554 ! startle response GO:0001964 21 14 0,000 0,04930488 0,08406317 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,04930488 0,0840009 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,04930488 0,08393873 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,04930488 0,08387664 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,04930488 0,08381465 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,04930488 0,08375275 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,04930488 0,08369094 ! glycine metabolic process GO:0006544 22 14 0,000 0,04930488 0,08362922 ! pituitary gland development GO:0021983 23 14 0,000 0,04930488 0,08356759 ! cellular response to starvation GO:0009267 21 14 0,000 0,04930488 0,08350605 ! lysosomal transport GO:0007041 20 14 0,000 0,04930488 0,08344461 ! regulation of heart rate GO:0002027 23 14 0,000 0,04930488 0,08338325 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,04930488 0,08332198 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,04930488 0,08326081 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,04930488 0,08319972 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,04930488 0,08313873 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,04930488 0,08307782 ! G1/S transition checkpoint GO:0031575 33 14 0,000 0,04930488 0,083017 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,04930488 0,08295627 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,04930488 0,08289563 ! axon cargo transport GO:0008088 27 14 0,000 0,04930488 0,08283508 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,04930488 0,08277461 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,04930488 0,08271424 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,04930488 0,08265395 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,04930488 0,08259375 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04930488 0,08253364 ! mRNA splice site selection GO:0006376 26 14 0,000 0,04930488 0,08247362 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,04930488 0,08241368 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,04930488 0,08235383 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,04930488 0,08229406 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,04930488 0,08223439 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,04930488 0,0821748 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,04930488 0,08211529 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,04930488 0,08205588 ! muscle maintenance GO:0046716 19 14 0,000 0,04930488 0,08199654 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,04930488 0,0819373 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,04930488 0,08187814 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,04930488 0,08181906 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,04930488 0,08176007 ! cell killing GO:0001906 20 14 0,000 0,04930488 0,08170117 ! release of cytochrome c from mitochondria GO:0001836 23 14 0,000 0,04930488 0,08164235 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,04930488 0,08158361 ! cilium assembly GO:0042384 20 14 0,000 0,04930488 0,08152496 ! peptide hormone secretion GO:0030072 23 14 0,000 0,04930488 0,08146639 ! extracellular structure organization GO:0043062 156 99 1,000 0,04960055 0,0818961 ! regulation of translation GO:0006417 151 100 1,000 0,050498 0,08331808 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 1,000 0,050498 0,08325835 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,05273365 0,08688209 ! metencephalon development GO:0022037 19 15 0,000 0,05273365 0,0868199 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,05273365 0,08675779 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,05273365 0,08669578 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,05273365 0,08663386 ! skin development GO:0043588 25 15 0,000 0,05273365 0,08657202 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,05273365 0,08651027 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,05273365 0,08644861 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 0,000 0,05273365 0,08638704 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,05273365 0,08632555 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,05273365 0,08626415 ! bile acid metabolic process GO:0008206 22 15 0,000 0,05273365 0,08620284 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,05273365 0,08614162 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,05273365 0,08608048 ! adult walking behavior GO:0007628 25 15 0,000 0,05273365 0,08601943 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,05273365 0,08595847 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,05273365 0,08589759 ! myoblast differentiation GO:0045445 27 15 0,000 0,05273365 0,0858368 ! centrosome cycle GO:0007098 16 15 0,000 0,05273365 0,08577609 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,05273365 0,08571548 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,05273365 0,08565494 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,05273365 0,08559449 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,05273365 0,08553413 ! cerebral cortex development GO:0021987 29 15 0,000 0,05273365 0,08547385 ! response to osmotic stress GO:0006970 22 15 0,000 0,05273365 0,08541366 ! vesicle coating GO:0006901 25 15 0,000 0,05273365 0,08535355 ! DNA integration GO:0015074 22 15 0,000 0,05273365 0,08529353 ! peptide secretion GO:0002790 27 15 0,000 0,05273365 0,08523359 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,05273365 0,08517373 ! regulation of vasodilation GO:0042312 24 15 0,000 0,05273365 0,08511396 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,05273365 0,08505428 ! neuron recognition GO:0008038 22 15 0,000 0,05273365 0,08499467 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,05273365 0,08493515 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,05273365 0,08487572 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,05273365 0,08481636 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,05273365 0,08475709 ! biomineral formation GO:0031214 18 15 0,000 0,05273365 0,0846979 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,05273365 0,0846388 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,05273365 0,08457977 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,05273365 0,08452083 ! dopamine metabolic process GO:0042417 30 15 0,000 0,05273365 0,08446198 ! organic cation transport GO:0015695 19 15 0,000 0,05273365 0,0844032 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,05273365 0,0843445 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,05273365 0,08428589 ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,05273365 0,08422736 ! defense response to virus GO:0051607 27 15 0,000 0,05273365 0,08416891 ! peptide hormone processing GO:0016486 19 15 0,000 0,05273365 0,08411054 ! protein secretion GO:0009306 27 16 0,000 0,05615025 0,08949798 ! hormone secretion GO:0046879 25 16 0,000 0,05615025 0,089436 ! bone remodeling GO:0046849 24 16 0,000 0,05615025 0,0893741 ! endothelial cell migration GO:0043542 22 16 0,000 0,05615025 0,0893123 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,05615025 0,08925057 ! protein amino acid acetylation GO:0006473 28 16 0,000 0,05615025 0,08918894 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,05615025 0,08912739 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,05615025 0,08906592 ! glial cell development GO:0021782 24 16 0,000 0,05615025 0,08900454 ! patterning of blood vessels GO:0001569 24 16 0,000 0,05615025 0,08894324 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,05615025 0,08888202 GO:0042744|hydrogen peroxide catabolic process, ! protein polyubiquitination GO:0000209 26 16 0,000 0,05615025 0,08882089 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,05615025 0,08875985 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,05615025 0,08869889 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,05615025 0,08863801 ! fructose metabolic process GO:0006000 20 16 0,000 0,05615025 0,08857722 ! regulation of protein binding GO:0043393 27 16 0,000 0,05615025 0,08851651 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,05615025 0,08845588 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,05615025 0,08839533 ! protein export from nucleus GO:0006611 24 16 0,000 0,05615025 0,08833487 ! negative regulation of immune response GO:0050777 28 16 0,000 0,05615025 0,08827449 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,05615025 0,08821419 ! DNA replication initiation GO:0006270 25 16 0,000 0,05615025 0,08815398 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,05615025 0,08809385 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,05615025 0,0880338 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,05615025 0,08797383 ! diencephalon development GO:0021536 25 16 0,000 0,05615025 0,08791394 ! oogenesis GO:0048477 23 16 0,000 0,05615025 0,08785414 ! neural crest cell migration GO:0001755 24 16 0,000 0,05615025 0,08779441 ! G1 phase GO:0051318 27 16 0,000 0,05615025 0,08773477 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,05615025 0,08767521 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,05615025 0,08761573 ! steroid catabolic process GO:0006706 22 16 0,000 0,05615025 0,08755633 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,05615025 0,08749701 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,05615025 0,08743777 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,05615025 0,08737861 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,05615025 0,08731953 ! sperm-egg recognition GO:0035036 16 16 0,000 0,05615025 0,08726053 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,05615025 0,08720161 ! nerve development GO:0021675 18 16 0,000 0,05615025 0,08714277 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,05615025 0,08708401 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,05615025 0,08702532 ! negative regulation of translation GO:0017148 22 16 0,000 0,05615025 0,08696672 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,05955473 0,09217757 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,05955473 0,09211558 ! negative regulation of defense response GO:0031348 19 17 0,000 0,05955473 0,09205368 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,05955473 0,09199185 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,05955473 0,09193011 ! glycerol metabolic process GO:0006071 20 17 0,000 0,05955473 0,09186846 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,05955473 0,09180688 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,05955473 0,09174539 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,05955473 0,09168398 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,05955473 0,09162266 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,05955473 0,09156141 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,05955473 0,09150025 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,05955473 0,09143917 ! memory GO:0007613 25 17 0,000 0,05955473 0,09137817 ! keratinization GO:0031424 17 17 0,000 0,05955473 0,09131725 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,05955473 0,09125641 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,05955473 0,09119565 ! retinoid metabolic process GO:0001523 22 17 0,000 0,05955473 0,09113498 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,05955473 0,09107438 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,05955473 0,09101387 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,05955473 0,09095343 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,05955473 0,09089308 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,05955473 0,09083281 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,05955473 0,09077261 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,05955473 0,0907125 ! membrane budding GO:0006900 29 17 0,000 0,05955473 0,09065246 ! heme metabolic process GO:0042168 27 17 0,000 0,05955473 0,09059251 ! actin filament bundle formation GO:0051017 26 17 0,000 0,05955473 0,09053263 ! body fluid secretion GO:0007589 27 17 0,000 0,05955473 0,09047283 ! stem cell differentiation GO:0048863 36 17 0,000 0,05955473 0,09041312 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,05955473 0,09035348 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,05955473 0,09029392 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,05955473 0,09023443 ! sensory perception of pain GO:0019233 23 17 0,000 0,05955473 0,09017503 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,05955473 0,0901157 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,05955473 0,09005646 ! negative regulation of intracellular transport GO:0032387 29 17 0,000 0,05955473 0,08999729 ! synaptogenesis GO:0007416 24 17 0,000 0,05955473 0,08993819 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,05955473 0,08987918 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,05955473 0,08982024 ! cell-cell junction organization GO:0045216 25 17 0,000 0,05955473 0,08976138 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,05955473 0,0897026 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,05955473 0,08964389 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,05955473 0,08958526 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,05955473 0,08952671 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,05955473 0,08946824 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,06294711 0,09450285 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,06294711 0,0944412 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,06294711 0,09437964 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,06294711 0,09431815 ! cAMP metabolic process GO:0046058 33 18 0,000 0,06294711 0,09425675 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,06294711 0,09419542 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,06294711 0,09413418 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,06294711 0,09407301 ! axis specification GO:0009798 26 18 0,000 0,06294711 0,09401192 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,06294711 0,09395092 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,06294711 0,09388999 ! pancreas development GO:0031016 26 18 0,000 0,06294711 0,09382914 ! apoptotic mitochondrial changes GO:0008637 29 18 0,000 0,06294711 0,09376837 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,06294711 0,09370768 ! glutamine metabolic process GO:0006541 23 18 0,000 0,06294711 0,09364706 ! response to retinoic acid GO:0032526 25 18 0,000 0,06294711 0,09358653 ! pigmentation during development GO:0048066 31 18 0,000 0,06294711 0,09352607 ! central nervous system neuron development GO:0021954 30 18 0,000 0,06294711 0,0934657 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,06294711 0,09340539 ! fucose metabolic process GO:0006004 26 18 0,000 0,06294711 0,09334517 ! response to fungus GO:0009620 19 18 0,000 0,06294711 0,09328503 ! peptide cross-linking GO:0018149 31 18 0,000 0,06294711 0,09322496 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,06294711 0,09316497 ! heart process GO:0003015 27 18 0,000 0,06294711 0,09310506 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,06294711 0,09304522 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,06294711 0,09298546 ! visual learning GO:0008542 35 18 0,000 0,06294711 0,09292578 ! somitogenesis GO:0001756 24 18 0,000 0,06294711 0,09286617 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,06294711 0,09280664 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,06294711 0,09274719 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,06294711 0,09268781 ! cellular response to nutrient levels GO:0031669 27 18 0,000 0,06294711 0,09262851 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,06294711 0,09256929 ! vitamin transport GO:0051180 24 18 0,000 0,06294711 0,09251014 ! hormone transport GO:0009914 27 18 0,000 0,06294711 0,09245106 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,06294711 0,09239206 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,06294711 0,09233314 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,06294711 0,09227429 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,06294711 0,09221552 ! cell-cell recognition GO:0009988 20 18 0,000 0,06294711 0,09215682 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,06294711 0,09209819 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,06294711 0,09203965 ! gut development GO:0048565 26 18 0,000 0,06294711 0,09198117 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,06294711 0,09192277 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,06294711 0,09186444 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,06632746 0,09673631 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,06632746 0,096675 ! positive regulation of ossification GO:0045778 30 19 0,000 0,06632746 0,09661378 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,06632746 0,09655263 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,06632746 0,09649156 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,06632746 0,09643056 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,06632746 0,09636965 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,06632746 0,09630881 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,06632746 0,09624805 ! regeneration GO:0031099 32 19 0,000 0,06632746 0,09618736 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,06632746 0,09612675 ! response to alkaloid GO:0043279 32 19 0,000 0,06632746 0,09606622 ! sensory perception of taste GO:0050909 23 19 0,000 0,06632746 0,09600576 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 0,000 0,06632746 0,09594538 ! smooth muscle contraction GO:0006939 36 19 0,000 0,06632746 0,09588507 ! peroxisome organization GO:0007031 29 19 0,000 0,06632746 0,09582485 ! digestive system process GO:0022600 30 19 0,000 0,06632746 0,09576469 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,06632746 0,09570461 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,06632746 0,09564461 ! response to vitamin A GO:0033189 26 19 0,000 0,06632746 0,09558468 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,06632746 0,09552483 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,06632746 0,09546505 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,06632746 0,09540535 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,06632746 0,09534572 ! response to starvation GO:0042594 30 19 0,000 0,06632746 0,09528617 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,06632746 0,09522669 ! plasma membrane fusion GO:0045026 23 19 0,000 0,06632746 0,09516728 ! cytolysis GO:0019835 20 19 0,000 0,06632746 0,09510795 ! renal system process GO:0003014 35 19 0,000 0,06632746 0,09504869 ! vasodilation GO:0042311 33 19 0,000 0,06632746 0,09498951 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,06632746 0,0949304 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,06632746 0,09487136 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,06632746 0,0948124 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,06632746 0,09475351 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,06632746 0,09469469 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,06632746 0,09463595 ! sarcomere organization GO:0045214 23 19 0,000 0,06632746 0,09457728 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,06632746 0,09451868 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,06632746 0,09446016 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,06632746 0,0944017 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,06632746 0,09434332 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,06632746 0,09428501 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,06632746 0,09422678 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,06632746 0,09416861 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,0696958 0,09888979 ! iron ion transport GO:0006826 37 20 0,000 0,0696958 0,09882882 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,0696958 0,09876792 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,0696958 0,09870711 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,0696958 0,09864636 ! response to vitamin GO:0033273 29 20 0,000 0,0696958 0,0985857 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,0696958 0,0985251 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,0696958 0,09846458 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,0696958 0,09840414 ! spinal cord development GO:0021510 31 20 0,000 0,0696958 0,09834377 ! response to ethanol GO:0045471 37 20 0,000 0,0696958 0,09828347 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,0696958 0,09822325 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,0696958 0,0981631 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,0696958 0,09810302 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,0696958 0,09804302 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,0696958 0,09798309 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,0696958 0,09792324 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,0696958 0,09786346 ! pallium development GO:0021543 38 20 0,000 0,0696958 0,09780375 ! DNA modification GO:0006304 28 20 0,000 0,0696958 0,09774411 ! collagen fibril organization GO:0030199 45 20 0,000 0,0696958 0,09768455 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,0696958 0,09762506 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,0696958 0,09756564 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,0696958 0,09750629 ! collagen catabolic process GO:0030574 25 20 0,000 0,0696958 0,09744702 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,0696958 0,09738781 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,0696958 0,09732868 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,0696958 0,09726962 ! alditol metabolic process GO:0019400 24 20 0,000 0,0696958 0,09721064 ! actin filament-based movement GO:0030048 34 20 0,000 0,0696958 0,09715172 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,07305218 0,10176864 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,07305218 0,10170704 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,07305218 0,10164551 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,07305218 0,10158405 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 0,000 0,07305218 0,10152267 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,07305218 0,10146137 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,07305218 0,10140013 GO:0009799|determination of symmetry, ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,07305218 0,10133898 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,07305218 0,10127789 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,07305218 0,10121688 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,07305218 0,10115594 ! protein amino acid acylation GO:0043543 37 21 0,000 0,07305218 0,10109508 ! vesicle docking GO:0048278 27 21 0,000 0,07305218 0,10103429 ! phototransduction GO:0007602 25 21 0,000 0,07305218 0,10097357 ! visual behavior GO:0007632 39 21 0,000 0,07305218 0,10091293 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,07305218 0,10085236 ! ovarian follicle development GO:0001541 30 21 0,000 0,07305218 0,10079186 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,07305218 0,10073143 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,07305218 0,10067107 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,07305218 0,10061079 ! cell aging GO:0007569 32 21 0,000 0,07305218 0,10055058 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,07305218 0,10049044 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,07305218 0,10043038 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,07305218 0,10037038 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,07305218 0,10031046 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,07305218 0,10025061 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,07305218 0,10019083 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,07305218 0,10013112 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,07305218 0,10007149 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,07305218 0,10001192 ! fatty acid transport GO:0015908 30 21 0,000 0,07305218 0,09995242 ! immunoglobulin production GO:0002377 33 21 0,000 0,07305218 0,099893 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,07305218 0,09983364 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,07305218 0,09977436 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,07305218 0,09971515 ! cellular response to extracellular stimulus GO:0031668 32 21 0,000 0,07305218 0,099656 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,07305218 0,09959693 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,07305218 0,09953793 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,07305218 0,099479 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,07305218 0,09942013 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,07305218 0,09936134 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,07305218 0,09930261 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,07305218 0,09924396 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,07305218 0,09918537 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,07305218 0,09912686 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,07305218 0,09906841 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,07639665 0,1035429 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,07639665 0,10348192 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,07639665 0,10342101 ! viral genome replication GO:0019079 29 22 0,000 0,07639665 0,10336017 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,07639665 0,10329941 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,07639665 0,10323872 ! leukocyte adhesion GO:0007159 38 22 0,000 0,07639665 0,10317809 ! molting cycle process GO:0022404 40 22 0,000 0,07639665 0,10311754 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,07639665 0,10305706 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,07639665 0,10299666 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,07639665 0,10293632 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,07639665 0,10287605 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,07639665 0,10281585 GO:0051297|centrosome organization, ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,07639665 0,10275573 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,07639665 0,10269567 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,07639665 0,10263569 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,07639665 0,10257577 ! lysosome organization GO:0007040 37 22 0,000 0,07639665 0,10251592 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,07639665 0,10245615 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,07639665 0,10239644 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,07639665 0,1023368 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,07639665 0,10227724 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,07639665 0,10221774 ! membrane depolarization GO:0051899 35 22 0,000 0,07639665 0,10215831 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,07639665 0,10209895 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,07639665 0,10203966 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,07639665 0,10198044 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,07639665 0,10192128 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,07639665 0,1018622 ! blastocyst development GO:0001824 37 22 0,000 0,07639665 0,10180318 ! neural tube closure GO:0001843 33 22 0,000 0,07639665 0,10174424 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,07639665 0,10168536 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,07972924 0,10605972 ! neuron fate commitment GO:0048663 32 23 0,000 0,07972924 0,10599841 ! embryonic pattern specification GO:0009880 31 23 0,000 0,07972924 0,10593717 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,07972924 0,10587601 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,07972924 0,10581492 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 0,000 0,07972924 0,10575389 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,07972924 0,10569294 ! vesicle targeting GO:0006903 32 23 0,000 0,07972924 0,10563206 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,07972924 0,10557124 ! osteoblast differentiation GO:0001649 40 23 0,000 0,07972924 0,1055105 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,07972924 0,10544983 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,07972924 0,10538922 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,07972924 0,10532869 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,07972924 0,10526823 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,07972924 0,10520783 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,07972924 0,10514751 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,07972924 0,10508725 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,07972924 0,10502706 ! cell fate determination GO:0001709 45 23 0,000 0,07972924 0,10496694 ! pentose metabolic process GO:0019321 31 23 0,000 0,07972924 0,10490689 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,07972924 0,10484691 ! spermatid development GO:0007286 33 23 0,000 0,07972924 0,104787 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,07972924 0,10472716 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,07972924 0,10466738 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,07972924 0,10460767 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,07972924 0,10454803 ! telomere organization GO:0032200 32 23 0,000 0,07972924 0,10448846 GO:0000723|telomere maintenance, ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,07972924 0,10442896 ! regulation of amine transport GO:0051952 38 23 0,000 0,07972924 0,10436952 ! liver development GO:0001889 40 23 0,000 0,07972924 0,10431015 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,08304999 0,10859294 ! initiation of viral infection GO:0019059 42 24 0,000 0,08304999 0,10853124 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,08304999 0,10846961 ! superoxide metabolic process GO:0006801 32 24 0,000 0,08304999 0,10840805 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,08304999 0,10834656 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,08304999 0,10828514 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,08304999 0,10822379 ! sperm motility GO:0030317 27 24 0,000 0,08304999 0,10816251 ! mitochondrial membrane organization GO:0007006 39 24 0,000 0,08304999 0,10810129 ! vacuole organization GO:0007033 39 24 0,000 0,08304999 0,10804015 ! neural crest cell development GO:0014032 39 24 0,000 0,08304999 0,10797908 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,08304999 0,10791807 ! primary neural tube formation GO:0014020 35 24 0,000 0,08304999 0,10785713 ! negative regulation of cell development GO:0010721 56 24 0,000 0,08304999 0,10779627 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,08304999 0,10773547 ! base-excision repair GO:0006284 31 24 0,000 0,08304999 0,10767474 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,08304999 0,10761408 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glutathione metabolic process GO:0006749 29 24 0,000 0,08304999 0,10755348 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,08304999 0,10749296 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,08304999 0,1074325 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,08304999 0,10737211 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,08635896 0,11158741 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,08635896 0,11152476 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,08635896 0,11146218 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,08635896 0,11139966 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,08635896 0,11133722 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,08635896 0,11127484 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,08635896 0,11121254 ! peptide transport GO:0015833 43 25 0,000 0,08635896 0,11115031 ! male gonad development GO:0008584 33 25 0,000 0,08635896 0,11108814 ! iron ion homeostasis GO:0055072 39 25 0,000 0,08635896 0,11102605 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,08635896 0,11096402 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,08635896 0,11090206 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,08635896 0,11084018 ! phospholipid transport GO:0015914 35 25 0,000 0,08635896 0,11077836 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,08635896 0,11071661 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,08635896 0,11065493 ! detection of light stimulus GO:0009583 30 25 0,000 0,08635896 0,11059332 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,08635896 0,11053177 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,08635896 0,1104703 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,08965616 0,11462434 ! translational initiation GO:0006413 43 26 0,000 0,08965616 0,11456066 ! regulation of pH GO:0006885 36 26 0,000 0,08965616 0,11449705 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,08965616 0,11443351 ! post-embryonic development GO:0009791 42 26 0,000 0,08965616 0,11437004 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,08965616 0,11430664 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,08965616 0,11424331 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,08965616 0,11418005 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,08965616 0,11411687 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,08965616 0,11405375 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,08965616 0,1139907 ! regulation of coagulation GO:0050818 39 26 0,000 0,08965616 0,11392772 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,09294166 0,11803745 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,09294166 0,11797231 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,09294166 0,11790724 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,09294166 0,11784224 ! membrane docking GO:0022406 39 27 0,000 0,09294166 0,11777731 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,09294166 0,11771246 ! catechol metabolic process GO:0009712 43 27 0,000 0,09294166 0,11764768 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,09294166 0,11758296 ! acute-phase response GO:0006953 42 27 0,000 0,09294166 0,11751832 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,09294166 0,11745375 ! myofibril assembly GO:0030239 36 27 0,000 0,09294166 0,11738925 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,09294166 0,11732482 ! response to ionizing radiation GO:0010212 47 27 0,000 0,09294166 0,11726046 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,09294166 0,11719618 ! natural killer cell activation GO:0030101 35 27 0,000 0,09294166 0,11713196 ! lipid oxidation GO:0034440 38 27 0,000 0,09294166 0,11706781 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,09294166 0,11700374 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,09294166 0,11693973 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,09294166 0,11687579 ! gene silencing GO:0016458 41 27 0,000 0,09294166 0,11681193 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,09621549 0,12086053 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,09621549 0,12079456 ! phenol metabolic process GO:0018958 44 28 0,000 0,09621549 0,12072866 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,09621549 0,12066283 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,09621549 0,12059707 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,09621549 0,12053139 ! cell junction assembly GO:0034329 56 28 0,000 0,09621549 0,12046578 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,09621549 0,12040023 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,09621549 0,12033476 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,09621549 0,12026936 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,09621549 0,12020404 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,09621549 0,12013878 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,09621549 0,12007359 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,09621549 0,12000848 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,09621549 0,11994343 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,09621549 0,11987846 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,09621549 0,11981355 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,09621549 0,11974872 ! mesoderm formation GO:0001707 46 28 0,000 0,09621549 0,11968395 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,09621549 0,11961926 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,09621549 0,11955464 ! BMP signaling pathway GO:0030509 40 28 0,000 0,09621549 0,11949008 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,09621549 0,1194256 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,09621549 0,11936118 ! neural tube formation GO:0001841 41 28 0,000 0,09621549 0,11929684 ! placenta development GO:0001890 37 28 0,000 0,09621549 0,11923256 ! regulation of B cell activation GO:0050864 42 28 0,000 0,09621549 0,11916835 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,09947769 0,12314246 ! regulation of innate immune response GO:0045088 38 29 0,000 0,09947769 0,12307622 ! ovulation cycle process GO:0022602 41 29 0,000 0,09947769 0,12301005 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,09947769 0,12294395 ! protein targeting to membrane GO:0006612 53 29 0,000 0,09947769 0,12287792 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,09947769 0,12281196 ! mismatch repair GO:0006298 34 29 0,000 0,09947769 0,12274608 ! muscle cell development GO:0055001 38 29 0,000 0,09947769 0,12268026 ! formation of primary germ layer GO:0001704 48 29 0,000 0,09947769 0,12261452 ! telencephalon development GO:0021537 52 29 0,000 0,09947769 0,12254884 ! eye morphogenesis GO:0048592 51 29 0,000 0,09947769 0,12248324 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,09947769 0,1224177 ! tissue homeostasis GO:0001894 42 29 0,000 0,09947769 0,12235224 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,1027283 0,12628279 ! collagen metabolic process GO:0032963 40 30 0,000 0,1027283 0,12621533 ! organic anion transport GO:0015711 51 30 0,000 0,1027283 0,12614794 ! cholesterol transport GO:0030301 46 30 0,000 0,1027283 0,12608063 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,1027283 0,12601338 ! spliceosome assembly GO:0000245 49 30 0,000 0,1027283 0,12594621 ! spindle organization GO:0007051 37 30 0,000 0,1027283 0,12587911 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,1027283 0,12581208 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,1027283 0,12574513 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,1027283 0,12567824 ! ceramide metabolic process GO:0006672 43 30 0,000 0,1027283 0,12561143 ! ovulation cycle GO:0042698 43 30 0,000 0,1027283 0,12554468 ! hindbrain development GO:0030902 45 30 0,000 0,1027283 0,12547801 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,1027283 0,12541141 ! adult locomotory behavior GO:0008344 47 30 0,000 0,1027283 0,12534488 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,1027283 0,12527842 ! response to heat GO:0009408 41 30 0,000 0,1027283 0,12521203 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,1027283 0,12514571 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,1027283 0,12507946 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,10596736 0,12895499 ! negative regulation of secretion GO:0051048 49 31 0,000 0,10596736 0,1288868 ! glial cell differentiation GO:0010001 55 31 0,000 0,10596736 0,12881868 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,10596736 0,12875063 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,10596736 0,12868265 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,10596736 0,12861474 ! odontogenesis GO:0042476 50 31 0,000 0,10596736 0,12854691 ! segmentation GO:0035282 41 31 0,000 0,10596736 0,12847914 ! regulation of striated muscle tissue development GO:0016202 47 31 0,000 0,10596736 0,12841145 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,10596736 0,12834383 ! metanephros development GO:0001656 58 31 0,000 0,10596736 0,12827628 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,10596736 0,1282088 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,10596736 0,1281414 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,10596736 0,12807406 ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,10596736 0,12800679 ! RNA modification GO:0009451 40 31 0,000 0,10596736 0,1279396 ! regulation of muscle development GO:0048634 48 32 0,000 0,10919492 0,13176722 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,10919492 0,13169812 ! negative regulation of DNA metabolic process GO:0051053 48 32 0,000 0,10919492 0,13162909 ! meiosis I GO:0007127 52 32 0,000 0,10919492 0,13156014 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,10919492 0,13149126 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,10919492 0,13142246 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,10919492 0,13135372 GO:0006639|acylglycerol metabolic process, ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,10919492 0,13128506 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,10919492 0,13121646 ! cytokine production GO:0001816 44 32 0,000 0,10919492 0,13114794 ! vesicle localization GO:0051648 47 32 0,000 0,10919492 0,1310795 ! RNA export from nucleus GO:0006405 44 33 0,000 0,11241101 0,13486975 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,11241101 0,13479943 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,11241101 0,13472919 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,11241101 0,13465902 ! ear morphogenesis GO:0042471 42 33 0,000 0,11241101 0,13458892 ! actomyosin structure organization GO:0031032 43 33 0,000 0,11241101 0,13451889 ! cell junction organization GO:0034330 63 33 0,000 0,11241101 0,13444894 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,11241101 0,13437906 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,11241101 0,13430925 ! nucleus organization GO:0006997 49 33 0,000 0,11241101 0,13423952 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,11241101 0,13416986 ! female gonad development GO:0008585 49 33 0,000 0,11241101 0,13410027 ! positive regulation of cell development GO:0010720 54 33 0,000 0,11241101 0,13403075 ! lipid homeostasis GO:0055088 55 33 0,000 0,11241101 0,1339613 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,11241101 0,13389193 ! regulation of proteolysis GO:0030162 50 33 0,000 0,11241101 0,13382263 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,11241101 0,1337534 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,11241101 0,13368424 ! androgen receptor signaling pathway GO:0030521 54 33 0,000 0,11241101 0,13361515 ! cytokinesis GO:0000910 52 33 0,000 0,11241101 0,13354613 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,11241101 0,13347719 ! mRNA catabolic process GO:0006402 48 34 0,000 0,11561567 0,13721157 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,11561567 0,13714081 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,11561567 0,13707012 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,11561567 0,1369995 ! feeding behavior GO:0007631 45 34 0,000 0,11561567 0,13692895 ! mitotic cell cycle checkpoint GO:0007093 63 34 0,000 0,11561567 0,13685848 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,11561567 0,13678808 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,11561567 0,13671775 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,11561567 0,1366475 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,11561567 0,13657731 ! neuron migration GO:0001764 46 34 0,000 0,11561567 0,1365072 ! female gamete generation GO:0007292 43 34 0,000 0,11561567 0,13643716 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,11561567 0,13636719 ! polyol metabolic process GO:0019751 44 34 0,000 0,11561567 0,1362973 ! aerobic respiration GO:0009060 47 34 0,000 0,11561567 0,13622747 ! dorsal/ventral pattern formation GO:0009953 44 34 0,000 0,11561567 0,13615772 ! embryonic organ development GO:0048568 45 34 0,000 0,11561567 0,13608804 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,11561567 0,13601843 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,11880894 0,13970376 ! Notch signaling pathway GO:0007219 56 35 0,000 0,11880894 0,13963237 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,11880894 0,13956106 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,11880894 0,13948982 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,11880894 0,13941865 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,11880894 0,13934756 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,11880894 0,13927653 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 51 35 0,000 0,11880894 0,13920558 ! pigment metabolic process GO:0042440 61 35 0,000 0,11880894 0,1391347 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,11880894 0,1390639 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! protein homooligomerization GO:0051260 52 35 0,000 0,11880894 0,13899316 ! positive regulation of transcription factor activity GO:0051091 49 36 0,000 0,12199086 0,1426431 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,12199086 0,14257062 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,12199086 0,14249821 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,12199086 0,14242588 ! organic ether metabolic process GO:0018904 46 36 0,000 0,12199086 0,14235362 ! neural tube development GO:0021915 50 36 0,000 0,12199086 0,14228143 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,12199086 0,14220932 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,12199086 0,14213728 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,12199086 0,14206531 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,12516148 0,14568391 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,12516148 0,14561022 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,12516148 0,1455366 ! learning GO:0007612 67 37 0,000 0,12516148 0,14546306 ! ion transmembrane transport GO:0034220 56 37 0,000 0,12516148 0,1453896 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,12516148 0,1453162 ! regulation of protein secretion GO:0050708 51 37 0,000 0,12516148 0,14524289 ! amino acid activation GO:0043038 52 37 0,000 0,12516148 0,14516964 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,12516148 0,14509647 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,12832083 0,14868408 ! gliogenesis GO:0042063 71 38 0,000 0,12832083 0,14860922 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,12832083 0,14853442 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,12832083 0,14845971 ! mesenchymal cell development GO:0014031 64 38 0,000 0,12832083 0,14838507 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 0,000 0,12832083 0,1483105 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,13146895 0,15187271 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,13146895 0,15179647 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,13146895 0,15172031 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,13146895 0,15164422 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,13146895 0,15156821 ! male sex differentiation GO:0046661 53 39 0,000 0,13146895 0,15149227 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,13146895 0,15141641 ! chromatin remodeling GO:0006338 68 39 0,000 0,13146895 0,15134063 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,13146895 0,15126492 ! developmental growth GO:0048589 62 39 0,000 0,13146895 0,15118929 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,13460587 0,1547194 ! response to calcium ion GO:0051592 58 40 0,000 0,13460587 0,15464211 ! regulation of tube size GO:0035150 60 40 0,000 0,13460587 0,15456491 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,13460587 0,15448778 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,13460587 0,15441073 ! inner ear development GO:0048839 57 40 0,000 0,13460587 0,15433375 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,13460587 0,15425686 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! T cell differentiation GO:0030217 65 40 0,000 0,13460587 0,15418004 ! double-strand break repair GO:0006302 67 40 0,000 0,13460587 0,15410329 ! B cell differentiation GO:0030183 62 40 0,000 0,13460587 0,15402662 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,13460587 0,15395003 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,13460587 0,15387351 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,13460587 0,15379707 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,13773165 0,15729037 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,13773165 0,15721231 ! glucose transport GO:0015758 52 41 0,000 0,13773165 0,15713433 ! striated muscle contraction GO:0006941 62 41 0,000 0,13773165 0,15705642 ! positive regulation of DNA binding GO:0043388 57 41 0,000 0,13773165 0,15697859 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,13773165 0,15690084 ! biopolymer methylation GO:0043414 62 41 0,000 0,13773165 0,15682317 ! mitochondrial transport GO:0006839 60 42 0,000 0,14084632 0,16029022 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,14084632 0,16021095 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,14084632 0,16013175 ! cellular component disassembly GO:0022411 64 42 0,000 0,14084632 0,16005264 ! hexose transport GO:0008645 54 42 0,000 0,14084632 0,1599736 GO:0015749|monosaccharide transport, ! branching morphogenesis of a tube GO:0048754 72 42 0,000 0,14084632 0,15989464 ! embryonic skeletal system development GO:0048706 56 42 0,000 0,14084632 0,15981576 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,14084632 0,15973695 ! excretion GO:0007588 63 42 0,000 0,14084632 0,15965822 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,14084632 0,15957957 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,14084632 0,159501 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,14084632 0,15942251 ! positive regulation of binding GO:0051099 59 43 0,000 0,14394991 0,16285529 ! neuromuscular process GO:0050905 79 43 0,000 0,14394991 0,16277522 ! activation of caspase activity GO:0006919 65 43 0,000 0,14394991 0,16269523 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,14394991 0,16261533 ! tRNA processing GO:0008033 49 43 0,000 0,14394991 0,16253549 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,14394991 0,16245574 ! vesicle organization GO:0016050 79 43 0,000 0,14394991 0,16237607 ! epithelial tube morphogenesis GO:0060562 65 43 0,000 0,14394991 0,16229647 ! methylation GO:0032259 64 43 0,000 0,14394991 0,16221695 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,14704247 0,16562081 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,14704247 0,16553974 ! glycolysis GO:0006096 53 44 0,000 0,14704247 0,16545875 ! regulation of ion transport GO:0043269 57 44 0,000 0,14704247 0,16537784 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,14704247 0,16529701 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,14704247 0,16521626 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,14704247 0,16513559 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,14704247 0,165055 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,14704247 0,16497448 ! RNA catabolic process GO:0006401 64 45 0,000 0,15012404 0,16834973 ! regulation of translational initiation GO:0006446 64 45 0,000 0,15012404 0,16826769 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,15012404 0,16818572 ! cell recognition GO:0008037 58 45 0,000 0,15012404 0,16810384 ! cell maturation GO:0048469 60 45 0,000 0,15012404 0,16802204 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,15319465 0,17137533 ! cell redox homeostasis GO:0045454 63 46 0,000 0,15319465 0,17129202 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,15319465 0,17120879 ! regulation of ossification GO:0030278 71 46 0,000 0,15319465 0,17112564 ! histone modification GO:0016570 68 46 0,000 0,15319465 0,17104257 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,15319465 0,17095958 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,15625434 0,17428951 ! viral infectious cycle GO:0019058 71 47 0,000 0,15625434 0,17420503 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,15625434 0,17412063 ! endocrine system development GO:0035270 83 47 0,000 0,15625434 0,17403631 ! covalent chromatin modification GO:0016569 75 47 0,000 0,15625434 0,17395207 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,15625434 0,17386791 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,15625434 0,17378384 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,15625434 0,17369984 ! regulation of neuron apoptosis GO:0043523 77 47 0,000 0,15625434 0,17361593 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,15625434 0,1735321 ! chloride transport GO:0006821 67 48 0,000 0,15930314 0,17683264 ! positive regulation of caspase activity GO:0043280 72 48 0,000 0,15930314 0,17674734 GO:0010952|positive regulation of peptidase activity, ! response to temperature stimulus GO:0009266 62 48 0,000 0,15930314 0,17666212 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,15930314 0,17657698 ! gastrulation GO:0007369 73 48 0,000 0,15930314 0,17649192 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,15930314 0,17640695 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,15930314 0,17632206 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,15930314 0,17623724 ! regulation of endocytosis GO:0030100 63 48 0,000 0,15930314 0,17615252 ! nuclear export GO:0051168 69 48 0,000 0,15930314 0,17606787 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,15930314 0,1759833 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,16234111 0,17925327 ! sensory perception of smell GO:0007608 61 49 0,000 0,16234111 0,17916725 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,16234111 0,17908132 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,16234111 0,17899547 ! RNA elongation GO:0006354 62 49 0,000 0,16234111 0,1789097 ! morphogenesis of a branching structure GO:0001763 86 49 0,000 0,16234111 0,17882402 ! germ cell development GO:0007281 68 49 0,000 0,16234111 0,17873842 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,16234111 0,1786529 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,16234111 0,17856746 ! regulation of actin filament length GO:0030832 72 50 0,000 0,16536827 0,18181024 ! ear development GO:0043583 72 50 0,000 0,16536827 0,18172338 ! membrane fusion GO:0006944 80 50 0,000 0,16536827 0,18163659 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,16536827 0,18154989 ! proton transport GO:0015992 75 50 0,000 0,16536827 0,18146328 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,16536827 0,18137674 ! positive regulation of secretion GO:0051047 71 51 0,000 0,16838467 0,18459711 ! hydrogen transport GO:0006818 77 51 0,000 0,16838467 0,18450916 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,16838467 0,1844213 ! adult behavior GO:0030534 80 51 0,000 0,16838467 0,18433352 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,16838467 0,18424583 ! transition metal ion transport GO:0000041 74 52 0,000 0,17139033 0,18744544 ! regulation of cellular component size GO:0032535 74 52 0,000 0,17139033 0,18735635 ! aging GO:0007568 79 52 0,000 0,17139033 0,18726735 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,17139033 0,18717843 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,17139033 0,18708959 ! establishment of organelle localization GO:0051656 85 52 0,000 0,17139033 0,18700084 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,17438531 0,19017838 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,17438531 0,19008825 ! skeletal system morphogenesis GO:0048705 78 53 0,000 0,17438531 0,1899982 ! kidney development GO:0001822 90 53 0,000 0,17438531 0,18990824 ! single fertilization GO:0007338 59 53 0,000 0,17438531 0,18981837 ! cell projection assembly GO:0030031 76 53 0,000 0,17438531 0,18972858 ! amino acid transport GO:0006865 84 54 0,000 0,17736963 0,19288423 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,17736963 0,19279307 ! regulation of mitosis GO:0007088 84 54 0,000 0,17736963 0,19270201 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,17736963 0,19261102 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,17736963 0,19252013 ! DNA catabolic process GO:0006308 67 54 0,000 0,17736963 0,19242931 ! detection of external stimulus GO:0009581 66 54 0,000 0,17736963 0,19233859 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,17736963 0,19224795 ! exocytosis GO:0006887 74 55 0,000 0,18034333 0,19537902 ! mesoderm development GO:0007498 76 55 0,000 0,18034333 0,19528704 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,18034333 0,19519514 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,18034333 0,19510332 ! DNA damage response, signal transduction GO:0042770 96 56 0,000 0,18330646 0,19821573 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,18330646 0,19812258 ! carbohydrate transport GO:0008643 74 57 0,000 0,18625904 0,20121925 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,18625904 0,20112478 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,18625904 0,2010304 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,18625904 0,20093611 ! camera-type eye development GO:0043010 88 57 0,000 0,18625904 0,20084191 ! secondary metabolic process GO:0019748 84 57 0,000 0,18625904 0,20074779 ! developmental maturation GO:0021700 75 57 0,000 0,18625904 0,20065377 ! gonad development GO:0008406 79 57 0,000 0,18625904 0,20055983 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,18920112 0,20363246 ! steroid hormone receptor signaling pathway GO:0030518 96 58 0,000 0,18920112 0,20353722 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,18920112 0,20344206 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,19213272 0,20649779 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,19213272 0,20640134 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,19213272 0,20630498 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,1950539 0,20934389 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,1950539 0,20924625 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,1950539 0,2091487 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,1950539 0,20905124 ! fertilization GO:0009566 68 60 0,000 0,1950539 0,20895387 ! meiosis GO:0007126 96 61 0,000 0,19796468 0,21197335 GO:0051327|M phase of meiotic cell cycle, ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,19796468 0,21187471 ! urogenital system development GO:0001655 101 61 0,000 0,19796468 0,21177617 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,19796468 0,21167771 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,19796468 0,21157935 ! extracellular matrix organization GO:0030198 103 61 0,000 0,19796468 0,21148108 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,19796468 0,2113829 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,19796468 0,21128481 ! amine catabolic process GO:0009310 90 62 0,000 0,2008651 0,21428095 ! neurotransmitter transport GO:0006836 81 62 0,000 0,2008651 0,21418161 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,2008651 0,21408236 ! negative regulation of cell growth GO:0030308 106 62 0,000 0,2008651 0,2139832 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,2008651 0,21388413 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,2008651 0,21378516 ! meiotic cell cycle GO:0051321 97 62 0,000 0,2008651 0,21368628 ! organelle localization GO:0051640 96 62 0,000 0,2008651 0,21358748 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 0,000 0,2037552 0,21656051 ! cell cycle checkpoint GO:0000075 108 64 0,000 0,20663501 0,21951987 ! negative regulation of cell size GO:0045792 108 64 0,000 0,20663501 0,21941852 ! appendage morphogenesis GO:0035107 93 64 0,000 0,20663501 0,21931727 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,20663501 0,21921611 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,20663501 0,21911504 ! hexose catabolic process GO:0019320 82 64 0,000 0,20663501 0,21901406 ! reproductive structure development GO:0048608 90 65 0,000 0,20950457 0,22195325 ! regulation of caspase activity GO:0043281 97 65 0,000 0,20950457 0,22185106 ! appendage development GO:0048736 94 65 0,000 0,20950457 0,22174897 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 0,000 0,20950457 0,22164697 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,20950457 0,22154506 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,20950457 0,22144325 ! defense response to bacterium GO:0042742 73 65 0,000 0,20950457 0,22134153 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,20950457 0,2212399 ! activation of immune response GO:0002253 83 65 0,000 0,20950457 0,22113837 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,21236391 0,22405367 ! antigen processing and presentation GO:0019882 96 66 0,000 0,21236391 0,22395094 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,21236391 0,2238483 ! regulation of immune effector process GO:0002697 101 66 0,000 0,21236391 0,22374576 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,21521308 0,22664381 ! regulation of endopeptidase activity GO:0052548 99 67 0,000 0,21521308 0,22654008 ! regulation of neuron differentiation GO:0045664 107 67 0,000 0,21521308 0,22643645 ! acute inflammatory response GO:0002526 92 68 0,000 0,2180521 0,22931862 ! learning or memory GO:0007611 123 68 0,000 0,2180521 0,22921382 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,2180521 0,2291091 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,2180521 0,22900449 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,2180521 0,22889997 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,2180521 0,22879554 ! inorganic anion transport GO:0015698 93 68 0,000 0,2180521 0,22869121 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,22088101 0,23155257 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,22088101 0,23144708 ! response to drug GO:0042493 108 69 0,000 0,22088101 0,23134168 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,22088101 0,23123638 ! response to metal ion GO:0010038 103 70 0,000 0,22369986 0,23408083 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,22369986 0,23397438 ! humoral immune response GO:0006959 86 70 0,000 0,22369986 0,23386803 ! eye development GO:0001654 111 70 0,000 0,22369986 0,23376178 ! amine transport GO:0015837 101 70 0,000 0,22369986 0,23365562 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,22369986 0,23354956 ! muscle cell differentiation GO:0042692 104 71 0,000 0,22650866 0,23637474 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,22650866 0,23626754 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,22650866 0,23616044 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,22650866 0,23605343 ! lymphocyte differentiation GO:0030098 113 71 0,000 0,22650866 0,23594652 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,22650866 0,23583971 ! regulation of peptidase activity GO:0052547 106 72 0,000 0,22930746 0,23864578 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,22930746 0,23853784 ! regulation of blood pressure GO:0008217 107 73 0,000 0,2320963 0,24132979 ! tube morphogenesis GO:0035239 118 73 0,000 0,2320963 0,24122074 ! mitochondrion organization GO:0007005 104 73 0,000 0,2320963 0,24111178 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,2320963 0,24100293 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,2320963 0,24089417 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,2348752 0,24366846 ! digestion GO:0007586 97 74 0,000 0,2348752 0,2435586 ! protein import into nucleus GO:0006606 118 74 0,000 0,2348752 0,24344884 ! positive regulation of lymphocyte activation GO:0051251 108 74 0,000 0,2348752 0,24333917 ! blood coagulation GO:0007596 116 75 0,000 0,23764421 0,24609711 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,23764421 0,24598636 ! negative regulation of growth GO:0045926 123 75 0,000 0,23764421 0,2458757 ! response to nutrient GO:0007584 104 75 0,000 0,23764421 0,24576515 ! regulation of ligase activity GO:0051340 114 75 0,000 0,23764421 0,24565469 ! nuclear import GO:0051170 121 75 0,000 0,23764421 0,24554433 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,23764421 0,24543407 ! amine biosynthetic process GO:0009309 97 76 0,000 0,24040335 0,24817222 ! tRNA metabolic process GO:0006399 95 76 0,000 0,24040335 0,24806089 ! response to unfolded protein GO:0006986 99 76 0,000 0,24040335 0,24794965 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,24315267 0,25067285 ! sex differentiation GO:0007548 105 77 0,000 0,24315267 0,25056055 ! protein ubiquitination GO:0016567 125 77 0,000 0,24315267 0,25044834 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,24315267 0,25033623 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,24315267 0,25022422 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,24589219 0,25293025 ! cellular respiration GO:0045333 107 79 0,000 0,24862195 0,25562382 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,24862195 0,2555096 ! T cell activation GO:0042110 134 79 0,000 0,24862195 0,25539549 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,24862195 0,25528147 ! chromatin assembly GO:0031497 102 80 0,000 0,25134199 0,25795921 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,25134199 0,25784415 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,25134199 0,25772919 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 0,000 0,25134199 0,25761434 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,25134199 0,25749959 ! forebrain development GO:0030900 131 80 0,000 0,25134199 0,25738494 ! hemostasis GO:0007599 125 81 0,000 0,25405234 0,26004467 ! mRNA transport GO:0051028 121 81 0,000 0,25405234 0,25992899 ! regulation of cell cycle process GO:0010564 122 81 0,000 0,25405234 0,25981342 ! response to protein stimulus GO:0051789 111 81 0,000 0,25405234 0,25969795 ! regulation of neurological system process GO:0031644 122 81 0,000 0,25405234 0,25958258 ! vitamin metabolic process GO:0006766 103 81 0,000 0,25405234 0,25946731 ! positive regulation of cell activation GO:0050867 120 81 0,000 0,25405234 0,25935214 GO:0002696|positive regulation of leukocyte activation, ! detection of stimulus GO:0051606 108 82 0,000 0,25675303 0,26199289 ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,2594441 0,26462147 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,26212557 0,26723795 ! sterol metabolic process GO:0016125 120 84 0,000 0,26212557 0,26711955 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,26479749 0,26972287 ! rRNA metabolic process GO:0016072 107 85 0,000 0,26479749 0,26960347 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,26479749 0,26948418 ! anterior/posterior pattern formation GO:0009952 124 85 0,000 0,26479749 0,26936499 ! cell cycle arrest GO:0007050 150 86 0,000 0,26745989 0,27195303 ! nucleosome organization GO:0034728 114 87 0,000 0,2701128 0,27452914 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,2701128 0,27440788 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,2701128 0,27428673 ! female pregnancy GO:0007565 130 87 0,000 0,2701128 0,27416569 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,27275626 0,27672668 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,27275626 0,27660467 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,27275626 0,27648276 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,27275626 0,27636097 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,27275626 0,27623927 ! regulation of neurogenesis GO:0050767 153 89 0,000 0,27539029 0,27878418 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,27539029 0,27866153 ! leukocyte differentiation GO:0002521 143 90 0,000 0,27801493 0,28119364 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,27801493 0,28107004 ! hormone metabolic process GO:0042445 121 90 0,000 0,27801493 0,28094655 ! RNA localization GO:0006403 135 91 0,000 0,28063022 0,28346487 ! ATP metabolic process GO:0046034 137 91 0,000 0,28063022 0,28334043 ! response to virus GO:0009615 122 91 0,000 0,28063022 0,28321611 ! positive regulation of immune response GO:0050778 121 92 0,000 0,28323618 0,28572071 ! DNA recombination GO:0006310 146 92 0,000 0,28323618 0,28559545 ! sulfur metabolic process GO:0006790 118 92 0,000 0,28323618 0,2854703 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,28583285 0,28796126 ! electron transport chain GO:0022900 123 94 0,000 0,28842027 0,29044072 ! response to oxidative stress GO:0006979 141 94 0,000 0,28842027 0,29031362 ! carboxylic acid transport GO:0046942 147 95 0,000 0,29099845 0,2927806 GO:0015849|organic acid transport, ! in utero embryonic development GO:0001701 147 96 0,000 0,29356745 0,29523617 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,29356745 0,29510714 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,29356745 0,29497821 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,29356745 0,2948494 ! protein maturation GO:0051604 129 96 0,000 0,29356745 0,2947207 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,29612728 0,29716088 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,30121959 0,30213914 ! protein import GO:0017038 156 99 0,000 0,30121959 0,30200744 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,30375213 0,3044139 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,30375213 0,30428132 ! divalent metal ion transport GO:0070838 171 100 0,000 0,30375213 0,30414885 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,30375213 0,30401649 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,30375213 0,30388426 ! protein localization in organelle GO:0033365 161 100 0,000 0,30375213 0,30375213