pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6435-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! induction of positive chemotaxis GO:0050930 15 9 3,000 7,019E-09 1,689E-05 ! regulation of positive chemotaxis GO:0050926 19 12 3,000 2,74E-08 3,296E-05 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of locomotion GO:0040017 39 21 3,000 3,25E-07 2,606E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 40 22 3,000 3,964E-07 2,384E-04 ! regulation of behavior GO:0050795 43 24 3,000 5,733E-07 2,759E-04 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 3,000 6,811E-07 2,731E-04 ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 7,243E-07 2,49E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 7,267E-07 2,185E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,16E-06 3,102E-04 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 2,476E-06 5,958E-04 ! chondrocyte differentiation GO:0002062 24 11 2,000 3,398E-06 7,433E-04 ! negative regulation of glucose import GO:0046325 17 11 2,000 3,398E-06 6,813E-04 GO:0010829|negative regulation of glucose transport, ! positive regulation of response to external stimulus GO:0032103 77 43 3,000 6,395E-06 1,184E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 7,451E-06 1,281E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 9,296E-06 1,491E-03 ! induction of apoptosis by extracellular signals GO:0008624 89 49 3,000 1,084E-05 1,63E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,384E-05 1,958E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 1,384E-05 1,849E-03 ! response to UV GO:0009411 104 53 3,000 1,486E-05 1,881E-03 ! positive regulation of cell migration GO:0030335 126 57 3,000 1,987E-05 2,39E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 2,000 2,306E-05 2,642E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 2,306E-05 2,522E-03 ! regulation of glucose import GO:0046324 29 20 2,000 2,306E-05 2,412E-03 GO:0010827|regulation of glucose transport, ! inactivation of MAPK activity GO:0000188 39 21 2,000 2,684E-05 2,691E-03 ! positive regulation of inflammatory response GO:0050729 35 21 2,000 2,684E-05 2,584E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 3,102E-05 2,871E-03 ! positive regulation of intracellular transport GO:0032388 37 22 2,000 3,102E-05 2,764E-03 ! positive regulation of cell motion GO:0051272 146 64 3,000 3,149E-05 2,706E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 3,775E-05 3,132E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 3,000 3,775E-05 3,027E-03 ! negative regulation of kinase activity GO:0033673 131 68 3,000 4,002E-05 3,106E-03 ! negative regulation of phosphorylation GO:0042326 47 24 2,000 4,061E-05 3,053E-03 ! negative regulation of transferase activity GO:0051348 140 72 3,000 5,013E-05 3,655E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 5,195E-05 3,676E-03 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 2,000 5,195E-05 3,571E-03 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of protein modification process GO:0031400 60 28 2,000 6,52E-05 4,357E-03 ! positive regulation of phosphorylation GO:0042327 129 79 3,000 7,214E-05 4,691E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 7,645E-05 4,841E-03 ! apoptotic cell clearance GO:0043277 20 5 1,000 7,645E-05 4,716E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 7,645E-05 4,599E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 7,645E-05 4,486E-03 ! early endosome to late endosome transport GO:0045022 12 5 1,000 7,645E-05 4,38E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 7,645E-05 4,278E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 3,000 7,954E-05 4,35E-03 GO:0045937|positive regulation of phosphate metabolic process, ! cellular response to hormone stimulus GO:0032870 167 82 3,000 8,345E-05 4,462E-03 ! negative regulation of transport GO:0051051 153 84 3,000 9,166E-05 4,794E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 2,000 9,792E-05 5,013E-03 ! leukocyte chemotaxis GO:0030595 50 33 2,000 1,075E-04 5,388E-03 GO:0060326|cell chemotaxis, ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 1,000 1,145E-04 5,621E-03 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! male sex determination GO:0030238 15 6 1,000 1,145E-04 5,508E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 1,361E-04 6,42E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 1,519E-04 7,026E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,6E-04 7,262E-03 ! mRNA stabilization GO:0048255 18 7 1,000 1,6E-04 7,127E-03 GO:0043489|RNA stabilization, ! spindle checkpoint GO:0031577 15 7 1,000 1,6E-04 6,998E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 1,6E-04 6,873E-03 ! negative regulation of nuclear division GO:0051784 14 7 1,000 1,6E-04 6,752E-03 GO:0045839|negative regulation of mitosis, ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 2,129E-04 8,832E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 2,129E-04 8,682E-03 ! ER overload response GO:0006983 12 8 1,000 2,129E-04 8,537E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 2,129E-04 8,397E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 2,129E-04 8,262E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 2,129E-04 8,131E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 2,129E-04 8,004E-03 ! regulation of intracellular protein transport GO:0033157 80 42 2,000 2,221E-04 8,222E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 2,383E-04 8,687E-03 ! leukocyte migration GO:0050900 68 45 2,000 2,729E-04 9,8E-03 ! induction of apoptosis by intracellular signals GO:0008629 93 45 2,000 2,729E-04 9,656E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 2,732E-04 9,527E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 2,732E-04 9,391E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 2,732E-04 9,259E-03 ! microtubule bundle formation GO:0001578 21 9 1,000 2,732E-04 9,13E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 2,732E-04 9,005E-03 ! receptor clustering GO:0043113 18 9 1,000 2,732E-04 8,884E-03 ! motor axon guidance GO:0008045 16 9 1,000 2,732E-04 8,765E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 2,732E-04 8,65E-03 ! postreplication repair GO:0006301 22 9 1,000 2,732E-04 8,538E-03 ! induction of an organ GO:0001759 14 9 1,000 2,732E-04 8,428E-03 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 2,000 2,914E-04 8,874E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 2,914E-04 8,763E-03 ! response to insulin stimulus GO:0032868 95 46 2,000 2,914E-04 8,654E-03 ! positive regulation of protein transport GO:0051222 72 46 2,000 2,914E-04 8,549E-03 ! positive regulation of defense response GO:0031349 76 47 2,000 3,106E-04 9,004E-03 ! regulation of JNK cascade GO:0046328 94 47 2,000 3,106E-04 8,896E-03 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 2,000 3,306E-04 9,359E-03 ! regulation of inflammatory response GO:0050727 75 48 2,000 3,306E-04 9,25E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 1,000 3,409E-04 9,428E-03 ! lung alveolus development GO:0048286 26 10 1,000 3,409E-04 9,321E-03 ! regulation of bone resorption GO:0045124 25 10 1,000 3,409E-04 9,216E-03 ! positive regulation of leukocyte migration GO:0002687 25 10 1,000 3,409E-04 9,114E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 3,409E-04 9,014E-03 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 3,409E-04 8,916E-03 ! localization within membrane GO:0051668 20 10 1,000 3,409E-04 8,82E-03 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 4,159E-04 0,01064591 ! blood vessel remodeling GO:0001974 29 11 1,000 4,159E-04 0,01053385 ! positive regulation of endothelial cell proliferation GO:0001938 22 11 1,000 4,159E-04 0,01042412 ! regulation of leukocyte migration GO:0002685 26 11 1,000 4,159E-04 0,01031666 ! developmental induction GO:0031128 19 11 1,000 4,159E-04 0,01021139 GO:0045168|cell-cell signaling involved in cell fate specification, ! regulation of embryonic development GO:0045995 27 11 1,000 4,159E-04 0,01010824 ! regulation of muscle contraction GO:0006937 81 52 2,000 4,191E-04 0,0100834 ! cartilage development GO:0051216 90 52 2,000 4,191E-04 9,984E-03 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 4,982E-04 0,0117518 ! virus-host interaction GO:0019048 29 12 1,000 4,982E-04 0,0116377 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 4,982E-04 0,0115258 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 4,982E-04 0,01141603 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 4,982E-04 0,01130833 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 1,000 4,982E-04 0,01120265 ! regulation of intracellular transport GO:0032386 101 57 2,000 5,493E-04 0,01223785 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 5,877E-04 0,01297302 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 33 13 1,000 5,877E-04 0,01285508 ! regulation of mRNA stability GO:0043488 31 13 1,000 5,877E-04 0,01273927 ! cytoplasmic sequestering of protein GO:0051220 24 13 1,000 5,877E-04 0,01262553 ! regulation of heart contraction GO:0008016 110 60 2,000 6,386E-04 0,01359694 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 6,386E-04 0,01347766 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 6,703E-04 0,01402336 ! actin cytoskeleton reorganization GO:0031532 33 14 1,000 6,844E-04 0,0141961 ! regulation of RNA stability GO:0043487 32 14 1,000 6,844E-04 0,01407477 ! positive regulation of cell size GO:0045793 27 15 1,000 7,883E-04 0,01607333 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 7,883E-04 0,01593826 ! regulation of cellular response to stress GO:0080135 128 67 2,000 8,815E-04 0,01767424 ! lung development GO:0030324 144 67 2,000 8,815E-04 0,01752817 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 8,993E-04 0,01773507 ! negative regulation of microtubule depolymerization GO:0007026 46 16 1,000 8,993E-04 0,01759088 GO:0031114|regulation of microtubule depolymerization, ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 8,993E-04 0,01744902 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 8,993E-04 0,01730943 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 8,993E-04 0,01717205 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! respiratory tube development GO:0030323 150 70 2,000 1,001E-03 0,01896838 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 1,017E-03 0,01912289 ! signal complex assembly GO:0007172 41 17 1,000 1,017E-03 0,01897466 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 1,000 1,017E-03 0,0188287 ! negative regulation of protein catabolic process GO:0042177 40 17 1,000 1,017E-03 0,01868497 ! negative regulation of homeostatic process GO:0032845 33 17 1,000 1,017E-03 0,01854341 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 1,000 1,017E-03 0,01840399 ! regulation of MAPKKK cascade GO:0043408 142 71 2,000 1,043E-03 0,01873303 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 2,000 1,087E-03 0,01936387 ! respiratory system development GO:0060541 153 72 2,000 1,087E-03 0,01922149 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 1,142E-03 0,0200636 ! peptidyl-serine phosphorylation GO:0018105 38 18 1,000 1,142E-03 0,01991821 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 1,142E-03 0,01977492 ! regulation of catabolic process GO:0009894 161 76 2,000 1,27E-03 0,02183409 ! positive regulation of translation GO:0045727 30 19 1,000 1,275E-03 0,02174846 ! lipid phosphorylation GO:0046834 35 19 1,000 1,275E-03 0,0215953 ! mitotic chromosome condensation GO:0007076 34 19 1,000 1,275E-03 0,02144429 ! neuromuscular junction development GO:0007528 34 19 1,000 1,275E-03 0,02129537 ! regulation of endothelial cell migration GO:0010594 44 19 1,000 1,275E-03 0,0211485 ! negative regulation of organelle organization GO:0010639 161 78 2,000 1,369E-03 0,02256643 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 1,000 1,414E-03 0,0231367 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 1,414E-03 0,02298037 GO:0010675|regulation of cellular carbohydrate metabolic process, ! peptidyl-serine modification GO:0018209 43 20 1,000 1,414E-03 0,02282614 ! negative regulation of T cell activation GO:0050868 40 20 1,000 1,414E-03 0,02267397 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 1,56E-03 0,02484971 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 1,712E-03 0,02710575 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 1,000 1,712E-03 0,02692858 ! protein stabilization GO:0050821 39 22 1,000 1,712E-03 0,02675372 ! positive regulation of DNA replication GO:0045740 43 23 1,000 1,872E-03 0,02906002 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 1,872E-03 0,02887374 ! gluconeogenesis GO:0006094 33 23 1,000 1,872E-03 0,02868983 ! activation of pro-apoptotic gene products GO:0008633 47 23 1,000 1,872E-03 0,02850825 ! sex determination GO:0007530 47 23 1,000 1,872E-03 0,02832895 ! negative regulation of catabolic process GO:0009895 50 23 1,000 1,872E-03 0,0281519 ! regulation of protein transport GO:0051223 154 87 2,000 1,874E-03 0,02800296 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein modification process GO:0031401 136 88 2,000 1,936E-03 0,02875476 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 2,039E-03 0,03009143 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 2,039E-03 0,02990795 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 2,039E-03 0,02972669 ! protein tetramerization GO:0051262 52 24 1,000 2,039E-03 0,02954761 ! regulation of defense response GO:0031347 149 92 2,000 2,198E-03 0,0316669 ! myelination GO:0042552 45 25 1,000 2,212E-03 0,03167728 ! vasculogenesis GO:0001570 46 25 1,000 2,212E-03 0,03148984 ! receptor metabolic process GO:0043112 46 25 1,000 2,212E-03 0,0313046 ! chromosome condensation GO:0030261 45 25 1,000 2,212E-03 0,03112154 ! response to endoplasmic reticulum stress GO:0034976 43 25 1,000 2,212E-03 0,0309406 ! interaction with host GO:0051701 62 25 1,000 2,212E-03 0,03076175 ! pyruvate metabolic process GO:0006090 38 26 1,000 2,392E-03 0,03307384 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 2,392E-03 0,03288485 ! regulation of endothelial cell proliferation GO:0001936 57 26 1,000 2,392E-03 0,032698 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 2,392E-03 0,03251327 ! interphase of mitotic cell cycle GO:0051329 209 95 2,000 2,408E-03 0,03255069 ! regulation of protein localization GO:0032880 176 97 2,000 2,555E-03 0,03434183 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 2,579E-03 0,03446671 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 1,000 2,579E-03 0,03427629 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 2,579E-03 0,03408796 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 2,579E-03 0,03390169 ! interphase GO:0051325 213 98 2,000 2,63E-03 0,03439484 ! circadian rhythm GO:0007623 50 28 1,000 2,772E-03 0,03604959 ! dendrite development GO:0016358 59 28 1,000 2,772E-03 0,03585577 ! ER-nuclear signaling pathway GO:0006984 48 28 1,000 2,772E-03 0,03566403 ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 2,772E-03 0,03547433 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 1,000 2,972E-03 0,03783202 ! ensheathment of neurons GO:0007272 57 30 1,000 3,178E-03 0,04024818 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 3,178E-03 0,04003746 ! negative regulation of transcription regulator activity GO:0090048 58 31 1,000 3,391E-03 0,04249891 GO:0043433|negative regulation of transcription factor activity, ! regulation of protein import into nucleus GO:0042306 63 32 1,000 3,611E-03 0,04501591 ! hexose biosynthetic process GO:0019319 48 32 1,000 3,611E-03 0,04478387 ! peripheral nervous system development GO:0007422 64 32 1,000 3,611E-03 0,04455421 ! positive regulation of catabolic process GO:0009896 64 32 1,000 3,611E-03 0,04432689 ! cell fate specification GO:0001708 52 33 1,000 3,837E-03 0,04686246 ! negative regulation of protein transport GO:0051224 69 33 1,000 3,837E-03 0,04662578 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 4,069E-03 0,04920204 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 1,000 4,308E-03 0,05182942 ! calcium-mediated signaling GO:0019722 62 35 1,000 4,308E-03 0,05157156 ! regulation of microtubule-based process GO:0032886 78 35 1,000 4,308E-03 0,05131626 ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 4,554E-03 0,05396972 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 1,000 4,554E-03 0,05370516 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! maintenance of protein location in cell GO:0032507 86 36 1,000 4,554E-03 0,05344319 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 4,554E-03 0,05318375 ! monosaccharide biosynthetic process GO:0046364 52 36 1,000 4,554E-03 0,05292683 ! negative regulation of cell activation GO:0050866 65 36 1,000 4,554E-03 0,05267237 ! sister chromatid segregation GO:0000819 58 37 1,000 4,805E-03 0,0553159 ! tissue remodeling GO:0048771 76 37 1,000 4,805E-03 0,05505249 ! negative regulation of DNA binding GO:0043392 68 37 1,000 4,805E-03 0,05479158 ! regulation of protein stability GO:0031647 73 37 1,000 4,805E-03 0,05453313 ! glycogen metabolic process GO:0005977 61 37 1,000 4,805E-03 0,05427711 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 5,063E-03 0,056922 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 5,063E-03 0,05665725 ! carbohydrate homeostasis GO:0033500 53 38 1,000 5,063E-03 0,05639495 GO:0042593|glucose homeostasis, ! glucan metabolic process GO:0044042 62 38 1,000 5,063E-03 0,05613506 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 86 39 1,000 5,327E-03 0,05879184 ! regulation of action potential in neuron GO:0019228 73 39 1,000 5,327E-03 0,05852339 ! negative regulation of binding GO:0051100 72 40 1,000 5,597E-03 0,06121307 ! maintenance of protein location GO:0045185 91 40 1,000 5,597E-03 0,06093609 ! hormone-mediated signaling GO:0009755 74 41 1,000 5,874E-03 0,06365759 ! regulation of T cell proliferation GO:0042129 71 41 1,000 5,874E-03 0,06337213 ! regulation of T cell differentiation GO:0045580 70 41 1,000 5,874E-03 0,06308922 ! negative regulation of protein complex disassembly GO:0043242 101 42 1,000 6,156E-03 0,0658305 ! alcohol biosynthetic process GO:0046165 59 42 1,000 6,156E-03 0,06553922 ! energy reserve metabolic process GO:0006112 74 43 1,000 6,445E-03 0,06831024 ! phagocytosis GO:0006909 90 43 1,000 6,445E-03 0,06801063 ! maintenance of location in cell GO:0051651 97 44 1,000 6,74E-03 0,07081041 ! cell growth GO:0016049 84 45 1,000 7,04E-03 0,07364895 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 7,347E-03 0,07652537 ! endosome transport GO:0016197 108 47 1,000 7,66E-03 0,07943883 ! vascular process in circulatory system GO:0003018 80 47 1,000 7,66E-03 0,07909789 ! JNK cascade GO:0007254 91 47 1,000 7,66E-03 0,07875986 ! positive regulation of cell cycle GO:0045787 89 48 1,000 7,979E-03 0,0816873 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 7,979E-03 0,08134117 ! regulation of mast cell proliferation GO:0070666 81 48 1,000 7,979E-03 0,08099796 ! regulation of action potential GO:0001508 95 49 1,000 8,303E-03 0,08393866 ! regulation of protein complex disassembly GO:0043244 113 49 1,000 8,303E-03 0,08358745 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 1,000 8,303E-03 0,08323917 ! peptide metabolic process GO:0006518 76 49 1,000 8,303E-03 0,08289378 ! negative regulation of immune system process GO:0002683 95 50 1,000 8,634E-03 0,08583629 ! regulation of leukocyte proliferation GO:0070663 88 51 1,000 8,97E-03 0,08881224 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of cell shape GO:0008360 125 51 1,000 8,97E-03 0,08844825 ! regulation of angiogenesis GO:0045765 114 52 1,000 9,312E-03 0,0914461 ! positive regulation of growth GO:0045927 90 52 1,000 9,312E-03 0,09107437 ! synapse organization GO:0050808 85 52 1,000 9,312E-03 0,09070565 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,01001313 0,09714354 GO:0010863|positive regulation of phospholipase C activity, ! negative regulation of cytoskeleton organization GO:0051494 124 54 1,000 0,01001313 0,0967534 ! cellular polysaccharide metabolic process GO:0044264 86 55 1,000 0,01037233 0,09982326 ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,01037233 0,09942556 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,01037233 0,09903102 ! heart morphogenesis GO:0003007 97 55 1,000 0,01037233 0,09863959 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,01073717 0,10170723 ! regulation of DNA replication GO:0006275 101 56 1,000 0,01073717 0,10130838 ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 1,000 0,01110764 0,10439446 ! regulation of bone remodeling GO:0046850 137 57 1,000 0,01110764 0,10398825 ! muscle fiber development GO:0048747 112 57 1,000 0,01110764 0,1035852 ! lipid modification GO:0030258 97 57 1,000 0,01110764 0,10318525 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,01110764 0,10278839 ! maintenance of location GO:0051235 118 57 1,000 0,01110764 0,10239456 ! regulation of tissue remodeling GO:0034103 140 58 1,000 0,01148369 0,10545712 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,01148369 0,10505615 ! viral reproductive process GO:0022415 126 62 1,000 0,01304311 0,1188702 ! regulation of homeostatic process GO:0032844 134 62 1,000 0,01304311 0,11842163 ! regulation of mitosis GO:0007088 105 63 1,000 0,01344661 0,12162607 GO:0051783|regulation of nuclear division, ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01386895 0,1249764 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01386895 0,12451007 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01386895 0,12404721 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01386895 0,12358778 ! neuron fate determination GO:0048664 7 5 0,000 0,01386895 0,12313173 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01386895 0,12267904 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01386895 0,12222967 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01386895 0,12178358 ! polyol transport GO:0015791 12 5 0,000 0,01386895 0,12134073 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01386895 0,12090109 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01386895 0,12046462 ! response to superoxide GO:0000303 10 5 0,000 0,01386895 0,1200313 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01386895 0,11960108 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01386895 0,11917393 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01386895 0,11874982 ! female meiosis GO:0007143 7 5 0,000 0,01386895 0,11832872 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01386895 0,1179106 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01386895 0,11749542 ! cobalt ion transport GO:0006824 11 5 0,000 0,01386895 0,11708316 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01386895 0,11667378 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01386895 0,11626725 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01386895 0,11586354 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01386895 0,11546263 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01386895 0,11506448 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01386895 0,11466907 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01386895 0,11427637 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01386895 0,11388635 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01386895 0,11349898 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01386895 0,11311424 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01386895 0,11273209 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01386895 0,11235253 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01386895 0,1119755 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01386895 0,111601 ! negative chemotaxis GO:0050919 14 5 0,000 0,01386895 0,111229 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01386895 0,11085947 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01386895 0,11049238 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01386895 0,11012772 ! behavioral response to pain GO:0048266 9 5 0,000 0,01386895 0,10976546 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01386895 0,10940557 ! Notch receptor processing GO:0007220 8 5 0,000 0,01386895 0,10904804 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01386895 0,10869283 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01386895 0,10833994 ! micturition GO:0060073 9 5 0,000 0,01386895 0,10798932 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01386895 0,10764097 ! copulation GO:0007620 9 5 0,000 0,01386895 0,10729486 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01386895 0,10695096 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01386895 0,10660927 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01386895 0,10626975 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01386895 0,10593238 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01386895 0,10559715 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01386895 0,10526404 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01386895 0,10493302 ! grooming behavior GO:0007625 6 5 0,000 0,01386895 0,10460408 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01386895 0,10427719 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01386895 0,10395234 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01386895 0,1036295 ! response to protozoan GO:0001562 10 5 0,000 0,01386895 0,10330867 ! lymph vessel development GO:0001945 10 5 0,000 0,01386895 0,10298981 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01386895 0,10267292 ! endochondral ossification GO:0001958 16 5 0,000 0,01386895 0,10235798 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01386895 0,10204495 ! parathyroid gland development GO:0060017 13 5 0,000 0,01386895 0,10173384 ! anagen GO:0042640 6 5 0,000 0,01386895 0,10142462 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01386895 0,10111727 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01386895 0,10081178 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01386895 0,10050813 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01386895 0,10020631 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01386895 0,09990629 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01386895 0,09960806 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01386895 0,09931161 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01386895 0,09901691 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01386895 0,09872396 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01386895 0,09843274 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01386895 0,09814324 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01386895 0,09785543 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01386895 0,0975693 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01386895 0,09728484 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01386895 0,09700204 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01386895 0,09672087 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01386895 0,09644133 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01386895 0,0961634 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01386895 0,09588707 ! histidine catabolic process GO:0006548 6 5 0,000 0,01386895 0,09561232 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01386895 0,09533914 ! microvillus organization GO:0032528 7 5 0,000 0,01386895 0,09506752 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01386895 0,09479744 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01386895 0,0945289 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01386895 0,09426186 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01386895 0,09399634 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01386895 0,0937323 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01386895 0,09346975 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01386895 0,09320866 ! polyol catabolic process GO:0046174 7 5 0,000 0,01386895 0,09294903 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01386895 0,09269083 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01386895 0,09243407 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01386895 0,09217873 ! muscle cell migration GO:0014812 8 5 0,000 0,01386895 0,09192479 ! mitochondrial fission GO:0000266 8 5 0,000 0,01386895 0,09167225 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01386895 0,0914211 ! mRNA transcription GO:0009299 9 5 0,000 0,01386895 0,09117131 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01386895 0,09092289 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01386895 0,09067582 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01386895 0,09043008 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01386895 0,09018568 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01386895 0,08994259 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01386895 0,08970081 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01386895 0,08946032 ! response to food GO:0032094 6 5 0,000 0,01386895 0,08922112 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01386895 0,0889832 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01386895 0,08874654 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01386895 0,08851114 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01386895 0,08827698 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01386895 0,08804406 ! forebrain neuron development GO:0021884 13 5 0,000 0,01386895 0,08781237 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01386895 0,08758189 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01386895 0,08735262 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01386895 0,08712454 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01386895 0,08689766 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01386895 0,08667195 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01386895 0,08644741 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01386895 0,08622403 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01386895 0,0860018 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01386895 0,08578072 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01386895 0,08556077 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01386895 0,08534194 ! basic amino acid transport GO:0015802 11 5 0,000 0,01386895 0,08512423 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01386895 0,08490763 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01386895 0,08469213 ! depyrimidination GO:0045008 10 5 0,000 0,01386895 0,08447772 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01386895 0,08426439 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01386895 0,08405214 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01386895 0,08384095 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01386895 0,08363083 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01386895 0,08342175 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01386895 0,08321372 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01386895 0,08300672 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01386895 0,08280074 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01386895 0,08259579 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01386895 0,08239185 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01386895 0,08218892 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01386895 0,08198698 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01386895 0,08178603 ! response to arsenic GO:0046685 10 5 0,000 0,01386895 0,08158606 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01386895 0,08138707 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01386895 0,08118905 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01386895 0,08099199 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01386895 0,08079588 ! response to cadmium ion GO:0046686 7 5 0,000 0,01386895 0,08060072 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01386895 0,08040651 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01386895 0,08021322 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01386895 0,08002086 ! decidualization GO:0046697 11 5 0,000 0,01386895 0,07982943 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01386895 0,0796389 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01386895 0,07944929 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01386895 0,07926057 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01386895 0,07907275 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01386895 0,07888582 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01386895 0,07869976 ! neural tube patterning GO:0021532 7 5 0,000 0,01386895 0,07851459 ! embryonic cleavage GO:0040016 6 5 0,000 0,01386895 0,07833028 ! peroxisome fission GO:0016559 5 5 0,000 0,01386895 0,07814684 ! histone demethylation GO:0016577 10 5 0,000 0,01386895 0,07796425 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01386895 0,07778252 ! mitotic recombination GO:0006312 9 5 0,000 0,01386895 0,07760163 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01386895 0,07742158 ! metaphase plate congression GO:0051310 7 5 0,000 0,01386895 0,07724236 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01386895 0,07706397 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01386895 0,07688641 ! enteric nervous system development GO:0048484 8 5 0,000 0,01386895 0,07670966 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01386895 0,07653372 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01386895 0,07635858 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01386895 0,07618425 ! muscle cell proliferation GO:0033002 11 5 0,000 0,01386895 0,07601071 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01386895 0,07583795 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01386895 0,07566599 ! plasminogen activation GO:0031639 5 5 0,000 0,01386895 0,0754948 ! B cell homeostasis GO:0001782 13 5 0,000 0,01386895 0,07532438 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01386895 0,07515473 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01386895 0,07498584 ! metaphase GO:0051323 8 5 0,000 0,01386895 0,07481771 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01386895 0,07465034 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01386895 0,07448371 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01386895 0,07431782 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01386895 0,07415267 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01386895 0,07398825 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01386895 0,07382456 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01386895 0,07366159 ! response to redox state GO:0051775 5 5 0,000 0,01386895 0,07349934 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01386895 0,0733378 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01386895 0,07317697 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01386895 0,07301685 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01386895 0,07285742 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01386895 0,07269869 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01386895 0,07254065 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01386895 0,0723833 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01386895 0,07222662 ! striatum development GO:0021756 9 5 0,000 0,01386895 0,07207063 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01386895 0,0719153 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01386895 0,07176065 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01386895 0,07160665 ! glial cell migration GO:0008347 11 5 0,000 0,01386895 0,07145332 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01386895 0,07130064 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01386895 0,07114861 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01386895 0,07099723 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01386895 0,0708465 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01386895 0,0706964 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01386895 0,07054693 ! neuroprotection GO:0043526 6 5 0,000 0,01386895 0,0703981 ! neural plate development GO:0001840 8 5 0,000 0,01386895 0,07024989 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01386895 0,07010231 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01386895 0,06995535 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01386895 0,069809 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01386895 0,06966326 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01386895 0,06951813 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01386895 0,0693736 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01386895 0,06922967 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01386895 0,06908634 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01386895 0,0689436 ! spindle assembly GO:0051225 6 5 0,000 0,01386895 0,06880144 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01386895 0,06865988 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01386895 0,06851889 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01386895 0,06837848 ! drug metabolic process GO:0017144 6 5 0,000 0,01386895 0,06823865 ! stem cell division GO:0017145 11 5 0,000 0,01386895 0,06809939 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01386895 0,06796069 ! organ regeneration GO:0031100 7 5 0,000 0,01386895 0,06782256 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01386895 0,06768499 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01386895 0,06754798 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01386895 0,06741152 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 1,000 0,01468929 0,07125489 ! actin filament organization GO:0007015 148 66 1,000 0,01468929 0,07111152 ! activation of MAPK activity GO:0000187 115 67 1,000 0,01511414 0,07302134 ! chromosome segregation GO:0007059 113 67 1,000 0,01511414 0,072875 ! adaptive immune response GO:0002250 119 67 1,000 0,01511414 0,07272925 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! viral reproduction GO:0016032 134 68 1,000 0,01554426 0,07464966 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01554426 0,07450096 ! cell cycle checkpoint GO:0000075 137 69 1,000 0,0159796 0,07643522 ! cAMP-mediated signaling GO:0019933 120 69 1,000 0,0159796 0,07628357 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01661985 0,07918289 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01661985 0,0790264 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,01661985 0,07887053 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,01661985 0,07871527 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01661985 0,07856062 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,01661985 0,07840658 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,01661985 0,07825315 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01661985 0,07810031 ! sleep GO:0030431 13 6 0,000 0,01661985 0,07794807 ! response to oxygen radical GO:0000305 11 6 0,000 0,01661985 0,07779642 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,01661985 0,07764536 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,01661985 0,07749488 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,01661985 0,07734499 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,01661985 0,07719567 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01661985 0,07704693 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01661985 0,07689877 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,01661985 0,07675117 ! forebrain regionalization GO:0021871 8 6 0,000 0,01661985 0,07660413 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01661985 0,07645766 ! male meiosis GO:0007140 7 6 0,000 0,01661985 0,07631175 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01661985 0,0761664 ! response to zinc ion GO:0010043 9 6 0,000 0,01661985 0,07602159 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01661985 0,07587734 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 0,000 0,01661985 0,07573363 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,01661985 0,07559047 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01661985 0,07544785 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01661985 0,07530576 ! malate metabolic process GO:0006108 11 6 0,000 0,01661985 0,07516421 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,01661985 0,07502319 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,01661985 0,07488269 ! protein refolding GO:0042026 15 6 0,000 0,01661985 0,07474273 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01661985 0,07460328 ! opsonization GO:0008228 8 6 0,000 0,01661985 0,07446435 ! mating behavior GO:0007617 7 6 0,000 0,01661985 0,07432594 ! neuron remodeling GO:0016322 15 6 0,000 0,01661985 0,07418805 ! erythrocyte maturation GO:0043249 7 6 0,000 0,01661985 0,07405066 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,01661985 0,07391379 ! equilibrioception GO:0050957 14 6 0,000 0,01661985 0,07377741 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,01661985 0,07364154 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,01661985 0,07350617 ! photoreceptor cell development GO:0042461 10 6 0,000 0,01661985 0,0733713 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,01661985 0,07323692 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01661985 0,07310303 ! response to interferon-gamma GO:0034341 15 6 0,000 0,01661985 0,07296963 ! toxin metabolic process GO:0009404 11 6 0,000 0,01661985 0,07283672 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01661985 0,07270429 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,01661985 0,07257234 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,01661985 0,07244087 ! nuclear migration GO:0007097 12 6 0,000 0,01661985 0,07230987 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,01661985 0,07217935 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01661985 0,07204929 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,01661985 0,07191971 ! thymic T cell selection GO:0045061 12 6 0,000 0,01661985 0,07179059 ! protein lipoylation GO:0009249 10 6 0,000 0,01661985 0,07166193 ! cysteine metabolic process GO:0006534 10 6 0,000 0,01661985 0,07153374 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01661985 0,071406 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,01661985 0,07127871 ! glutamate catabolic process GO:0006538 10 6 0,000 0,01661985 0,07115188 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,01661985 0,0710255 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01661985 0,07089957 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,01661985 0,07077409 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,01661985 0,07064904 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01661985 0,07052444 ! hyperosmotic response GO:0006972 9 6 0,000 0,01661985 0,07040028 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,01661985 0,07027655 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,01661985 0,07015326 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01661985 0,0700304 ! urea metabolic process GO:0019627 7 6 0,000 0,01661985 0,06990797 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01661985 0,06978597 ! neutrophil activation GO:0042119 8 6 0,000 0,01661985 0,06966439 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01661985 0,06954323 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,01661985 0,0694225 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01661985 0,06930218 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,01661985 0,06918228 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01661985 0,06906279 ! neuron apoptosis GO:0051402 9 6 0,000 0,01661985 0,06894372 ! nucleoside salvage GO:0043174 9 6 0,000 0,01661985 0,06882506 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,01661985 0,0687068 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01661985 0,06858895 ! T cell mediated immunity GO:0002456 16 6 0,000 0,01661985 0,0684715 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01661985 0,06835446 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,01661985 0,06823781 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,01661985 0,06812156 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01661985 0,06800571 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,01661985 0,06789025 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,01661985 0,06777518 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,01661985 0,0676605 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01661985 0,06754621 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,01661985 0,06743231 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,01661985 0,06731878 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,01661985 0,06720564 ! establishment of spindle localization GO:0051293 12 6 0,000 0,01661985 0,06709288 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,01661985 0,0669805 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01661985 0,06686849 GO:0045686|negative regulation of glial cell differentiation, ! monocyte differentiation GO:0030224 12 6 0,000 0,01661985 0,06675686 ! neural nucleus development GO:0048857 14 6 0,000 0,01661985 0,0666456 ! response to UV-C GO:0010225 11 6 0,000 0,01661985 0,06653471 ! astrocyte development GO:0014002 15 6 0,000 0,01661985 0,06642418 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,01661985 0,06631403 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01661985 0,06620424 ! interaction with symbiont GO:0051702 13 6 0,000 0,01661985 0,06609481 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01661985 0,06598574 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,01661985 0,06587703 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,01661985 0,06576868 ! response to copper ion GO:0046688 10 6 0,000 0,01661985 0,06566069 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,01661985 0,06555305 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,01661985 0,06544576 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01661985 0,06533882 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,01661985 0,06523223 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01661985 0,06512599 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,01661985 0,06502009 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01661985 0,06491454 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,01661985 0,06480933 ! hair follicle maturation GO:0048820 7 6 0,000 0,01661985 0,06470446 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01661985 0,06459993 ! Schwann cell development GO:0014044 15 6 0,000 0,01661985 0,06449574 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,01661985 0,06439188 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,01661985 0,06428836 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,01661985 0,06418517 ! subpallium development GO:0021544 10 6 0,000 0,01661985 0,0640823 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,01661985 0,06397977 ! histone ubiquitination GO:0016574 8 6 0,000 0,01661985 0,06387757 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,01661985 0,06377569 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01661985 0,06367414 ! G2 phase GO:0051319 16 6 0,000 0,01661985 0,06357291 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,01661985 0,063472 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01661985 0,06337141 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,01661985 0,06327114 ! membrane to membrane docking GO:0022614 14 6 0,000 0,01661985 0,06317118 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01661985 0,06307154 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,01661985 0,06297222 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01661985 0,0628732 ! receptor internalization GO:0031623 10 6 0,000 0,01661985 0,0627745 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,01661985 0,06267611 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,01661985 0,06257803 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01661985 0,06248025 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,01661985 0,06238277 ! protein deubiquitination GO:0016579 14 6 0,000 0,01661985 0,0622856 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,01661985 0,06218874 ! protein destabilization GO:0031648 9 6 0,000 0,01661985 0,06209217 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01661985 0,0619959 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,01661985 0,06189994 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,01661985 0,06180426 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,01661985 0,06170889 ! progesterone metabolic process GO:0042448 10 6 0,000 0,01661985 0,0616138 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,01661985 0,06151901 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,01661985 0,06142451 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,01661985 0,0613303 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,01661985 0,06123638 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01661985 0,06114275 ! determination of adult lifespan GO:0008340 15 6 0,000 0,01661985 0,0610494 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,01661985 0,06095634 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,01661985 0,06086356 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01661985 0,06077106 ! catecholamine transport GO:0051937 9 6 0,000 0,01661985 0,06067884 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,01661985 0,06058691 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01661985 0,06049525 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,01661985 0,06040386 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,01661985 0,06031276 ! maternal placenta development GO:0001893 12 6 0,000 0,01661985 0,06022192 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,01661985 0,06013137 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01661985 0,06004108 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,01661985 0,05995106 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,01661985 0,05986131 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,01661985 0,05977184 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,01661985 0,05968262 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,01661985 0,05959368 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,01731668 0,06199991 ! axon guidance GO:0007411 139 73 1,000 0,01777262 0,06353779 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,01823364 0,06508921 GO:0090046|regulation of transcription regulator activity, ! cell-matrix adhesion GO:0007160 163 75 1,000 0,01869969 0,06665399 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,01869969 0,06655539 ! rhythmic process GO:0048511 128 75 1,000 0,01869969 0,06645708 ! tRNA transcription GO:0009304 14 7 0,000 0,01936316 0,06871353 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01936316 0,06861233 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01936316 0,06851143 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01936316 0,06841083 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01936316 0,06831052 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01936316 0,0682105 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01936316 0,06811078 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01936316 0,06801135 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01936316 0,0679122 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01936316 0,06781335 ! prostate gland development GO:0030850 13 7 0,000 0,01936316 0,06771478 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01936316 0,0676165 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01936316 0,06751851 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01936316 0,0674208 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01936316 0,06732337 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01936316 0,06722622 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01936316 0,06712935 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01936316 0,06703277 ! regulation of lipid kinase activity GO:0043550 13 7 0,000 0,01936316 0,06693645 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01936316 0,06684042 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01936316 0,06674466 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01936316 0,06664917 ! glycolipid transport GO:0046836 10 7 0,000 0,01936316 0,06655396 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01936316 0,06645902 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,01936316 0,06636435 ! N-terminal protein amino acid acetylation GO:0006474 13 7 0,000 0,01936316 0,06626995 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01936316 0,06617581 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01936316 0,06608195 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01936316 0,06598835 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01936316 0,06589501 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01936316 0,06580194 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01936316 0,06570913 ! pericardium development GO:0060039 14 7 0,000 0,01936316 0,06561658 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01936316 0,06552429 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01936316 0,06543226 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01936316 0,06534049 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01936316 0,06524898 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01936316 0,06515772 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01936316 0,06506672 ! lipoprotein transport GO:0042953 14 7 0,000 0,01936316 0,06497597 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01936316 0,06488548 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01936316 0,06479523 ! rhythmic behavior GO:0007622 15 7 0,000 0,01936316 0,06470524 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01936316 0,0646155 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01936316 0,064526 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01936316 0,06443675 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01936316 0,06434775 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01936316 0,064259 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01936316 0,06417048 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01936316 0,06408222 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01936316 0,06399419 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01936316 0,06390641 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01936316 0,06381887 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01936316 0,06373156 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01936316 0,0636445 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01936316 0,06355767 ! spinal cord patterning GO:0021511 13 7 0,000 0,01936316 0,06347108 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01936316 0,06338472 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01936316 0,0632986 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01936316 0,06321272 ! adrenal gland development GO:0030325 17 7 0,000 0,01936316 0,06312706 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01936316 0,06304164 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01936316 0,06295645 ! ovulation GO:0030728 9 7 0,000 0,01936316 0,06287149 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01936316 0,06278675 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01936316 0,06270225 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01936316 0,06261797 ! microtubule nucleation GO:0007020 20 7 0,000 0,01936316 0,06253392 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01936316 0,0624501 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01936316 0,0623665 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01936316 0,06228312 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01936316 0,06219996 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01936316 0,06211703 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01936316 0,06203432 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01936316 0,06195182 ! galactose metabolic process GO:0006012 13 7 0,000 0,01936316 0,06186955 ! vesicle fusion GO:0006906 17 7 0,000 0,01936316 0,0617875 ! response to dietary excess GO:0002021 8 7 0,000 0,01936316 0,06170566 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01936316 0,06162404 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01936316 0,06154263 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01936316 0,06146144 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01936316 0,06138046 ! organ growth GO:0035265 15 7 0,000 0,01936316 0,0612997 ! purine salvage GO:0043101 10 7 0,000 0,01936316 0,06121915 ! nucleoside transport GO:0015858 8 7 0,000 0,01936316 0,06113881 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01936316 0,06105868 ! parturition GO:0007567 14 7 0,000 0,01936316 0,06097876 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01936316 0,06089905 ! rRNA modification GO:0000154 14 7 0,000 0,01936316 0,06081955 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01936316 0,06074025 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01936316 0,06066116 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01936316 0,06058228 ! macrophage differentiation GO:0030225 11 7 0,000 0,01936316 0,0605036 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01936316 0,06042513 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01936316 0,06034685 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01936316 0,06026879 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01936316 0,06019092 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01936316 0,06011325 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01936316 0,06003579 ! fibrinolysis GO:0042730 10 7 0,000 0,01936316 0,05995852 ! eating behavior GO:0042755 7 7 0,000 0,01936316 0,05988145 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01936316 0,05980459 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01936316 0,05972791 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01936316 0,05965144 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01936316 0,05957516 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01936316 0,05949907 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01936316 0,05942318 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01936316 0,05934748 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01936316 0,05927197 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01936316 0,05919666 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01936316 0,05912154 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01936316 0,05904661 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01936316 0,05897186 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01936316 0,05889731 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01936316 0,05882294 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01936316 0,05874877 ! regulation of meiosis GO:0040020 12 7 0,000 0,01936316 0,05867478 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01936316 0,05860097 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01936316 0,05852735 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01936316 0,05845392 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01936316 0,05838067 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01936316 0,0583076 ! transcription termination GO:0006353 13 7 0,000 0,01936316 0,05823471 ! response to tumor cell GO:0002347 13 7 0,000 0,01936316 0,05816201 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01936316 0,05808949 ! anaphase GO:0051322 17 7 0,000 0,01936316 0,05801715 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01936316 0,05794499 ! axonal fasciculation GO:0007413 18 7 0,000 0,01936316 0,05787301 ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01936316 0,05780121 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01936316 0,05772958 ! diuresis GO:0030146 12 7 0,000 0,01936316 0,05765813 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01936316 0,05758686 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01936316 0,05751577 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01936316 0,05744485 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01936316 0,0573741 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01936316 0,05730353 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01936316 0,05723314 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01936316 0,05716291 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01936316 0,05709286 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01936316 0,05702298 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01936316 0,05695327 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01936316 0,05688373 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01936316 0,05681436 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01936316 0,05674515 ! lymph node development GO:0048535 10 7 0,000 0,01936316 0,05667612 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01936316 0,05660726 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01936316 0,05653856 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01936316 0,05647003 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01936316 0,05640166 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01936316 0,05633346 ! adult feeding behavior GO:0008343 9 7 0,000 0,01936316 0,05626543 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01936316 0,05619755 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01936316 0,05612985 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01936316 0,0560623 ! muscle adaptation GO:0043500 14 7 0,000 0,01936316 0,05599492 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01936316 0,0559277 ! retina homeostasis GO:0001895 12 7 0,000 0,01936316 0,05586064 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01936316 0,05579374 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01936316 0,055727 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01936316 0,05566042 ! protein prenylation GO:0018342 18 7 0,000 0,01936316 0,055594 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01936316 0,05552774 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01936316 0,05546163 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01936316 0,05539569 ! protein oligomerization GO:0051259 139 78 1,000 0,02012777 0,05751474 ! regulation of adenylate cyclase activity GO:0045761 156 80 1,000 0,02110446 0,06023407 ! response to hypoxia GO:0001666 171 81 1,000 0,0216001 0,06157564 ! cell-substrate adhesion GO:0031589 171 81 1,000 0,0216001 0,06150277 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02209892 0,06284869 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02209892 0,06277449 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02209892 0,06270046 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02209892 0,06262661 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02209892 0,06255293 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02209892 0,06247943 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02209892 0,06240609 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02209892 0,06233293 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02209892 0,06225994 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02209892 0,06218712 ! meiotic prophase I GO:0007128 13 8 0,000 0,02209892 0,06211448 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02209892 0,062042 ! oligopeptide transport GO:0006857 15 8 0,000 0,02209892 0,06196969 ! UTP metabolic process GO:0046051 8 8 0,000 0,02209892 0,06189755 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02209892 0,06182557 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02209892 0,06175376 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02209892 0,06168212 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02209892 0,06161065 ! succinate metabolic process GO:0006105 14 8 0,000 0,02209892 0,06153934 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02209892 0,0614682 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02209892 0,06139722 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02209892 0,0613264 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02209892 0,06125575 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02209892 0,06118526 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02209892 0,06111493 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02209892 0,06104477 ! reflex GO:0060004 16 8 0,000 0,02209892 0,06097476 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02209892 0,06090492 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02209892 0,06083523 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02209892 0,0607657 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02209892 0,06069634 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02209892 0,06062713 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02209892 0,06055808 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02209892 0,06048918 ! pigment granule organization GO:0048753 16 8 0,000 0,02209892 0,06042044 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02209892 0,06035186 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02209892 0,06028344 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02209892 0,06021517 ! histidine metabolic process GO:0006547 16 8 0,000 0,02209892 0,06014705 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02209892 0,06007909 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02209892 0,06001128 ! glycine catabolic process GO:0006546 13 8 0,000 0,02209892 0,05994362 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02209892 0,05987612 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02209892 0,05980876 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02209892 0,05974156 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02209892 0,05967451 ! melanin metabolic process GO:0006582 15 8 0,000 0,02209892 0,05960761 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02209892 0,05954086 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02209892 0,05947426 ! macrophage activation GO:0042116 12 8 0,000 0,02209892 0,05940781 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02209892 0,05934151 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02209892 0,05927535 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02209892 0,05920934 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02209892 0,05914348 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02209892 0,05907777 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02209892 0,0590122 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02209892 0,05894678 ! osteoblast development GO:0002076 16 8 0,000 0,02209892 0,0588815 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02209892 0,05881636 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02209892 0,05875137 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02209892 0,05868652 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02209892 0,05862182 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02209892 0,05855726 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02209892 0,05849284 ! response to UV-B GO:0010224 16 8 0,000 0,02209892 0,05842856 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02209892 0,05836443 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02209892 0,05830043 ! intermediate filament organization GO:0045109 12 8 0,000 0,02209892 0,05823657 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,02209892 0,05817286 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02209892 0,05810928 ! cellular extravasation GO:0045123 12 8 0,000 0,02209892 0,05804584 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02209892 0,05798254 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02209892 0,05791938 ! response to antibiotic GO:0046677 11 8 0,000 0,02209892 0,05785636 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02209892 0,05779347 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02209892 0,05773072 ! DNA topological change GO:0006265 12 8 0,000 0,02209892 0,0576681 ! response to tropane GO:0014073 15 8 0,000 0,02209892 0,05760562 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02209892 0,05754328 ! melanosome transport GO:0032402 13 8 0,000 0,02209892 0,05748107 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02209892 0,057419 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02209892 0,05735706 ! mast cell activation GO:0045576 14 8 0,000 0,02209892 0,05729525 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02209892 0,05723358 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02209892 0,05717203 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02209892 0,05711062 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02209892 0,05704935 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02209892 0,0569882 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02209892 0,05692719 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,02209892 0,0568663 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02209892 0,05680555 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02209892 0,05674492 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02209892 0,05668443 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02209892 0,05662406 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02209892 0,05656382 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02209892 0,05650371 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02209892 0,05644373 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02209892 0,05638387 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02209892 0,05632414 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02209892 0,05626454 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02209892 0,05620506 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02209892 0,05614571 ! hormone catabolic process GO:0042447 17 8 0,000 0,02209892 0,05608649 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02209892 0,05602739 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02209892 0,05596841 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02209892 0,05590956 ! ATP catabolic process GO:0006200 11 8 0,000 0,02209892 0,05585083 ! blastocyst growth GO:0001832 19 8 0,000 0,02209892 0,05579223 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02209892 0,05573374 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02209892 0,05567538 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02209892 0,05561715 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02209892 0,05555903 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02209892 0,05550103 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02209892 0,05544316 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02209892 0,05538541 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02209892 0,05532777 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02209892 0,05527026 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02209892 0,05521287 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02209892 0,05515559 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02209892 0,05509844 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02209892 0,0550414 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02209892 0,05498448 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02209892 0,05492768 GO:0000076|DNA replication checkpoint, ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02209892 0,05487099 ! regulation of cAMP biosynthetic process GO:0030817 161 82 1,000 0,02210057 0,05481852 ! regulation of cyclase activity GO:0031279 159 82 1,000 0,02210057 0,05476207 ! response to oxygen levels GO:0070482 176 83 1,000 0,02260583 0,05595641 ! regulation of lyase activity GO:0051339 160 83 1,000 0,02260583 0,0558989 ! regulation of cAMP metabolic process GO:0030814 168 84 1,000 0,02311586 0,0571014 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 1,000 0,02467424 0,06088844 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! axon extension GO:0048675 15 9 0,000 0,02482713 0,06120294 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02482713 0,06114029 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02482713 0,06107778 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02482713 0,06101539 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02482713 0,06095313 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02482713 0,06089099 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02482713 0,06082899 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02482713 0,06076711 ! phosphate transport GO:0006817 19 9 0,000 0,02482713 0,06070535 ! reproductive behavior GO:0019098 19 9 0,000 0,02482713 0,06064372 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02482713 0,06058222 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02482713 0,06052084 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02482713 0,06045958 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02482713 0,06039845 ! GTP metabolic process GO:0046039 9 9 0,000 0,02482713 0,06033744 ! RNA methylation GO:0001510 15 9 0,000 0,02482713 0,06027655 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02482713 0,06021579 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02482713 0,06015515 ! artery development GO:0060840 24 9 0,000 0,02482713 0,06009463 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02482713 0,06003424 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02482713 0,05997396 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02482713 0,05991381 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02482713 0,05985377 ! chemosensory behavior GO:0007635 20 9 0,000 0,02482713 0,05979386 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02482713 0,05973407 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02482713 0,05967439 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02482713 0,05961484 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02482713 0,0595554 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02482713 0,05949608 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02482713 0,05943688 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02482713 0,0593778 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02482713 0,05931883 ! protein targeting to ER GO:0045047 22 9 0,000 0,02482713 0,05925999 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02482713 0,05920125 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02482713 0,05914264 ! T cell selection GO:0045058 23 9 0,000 0,02482713 0,05908414 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02482713 0,05902576 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02482713 0,05896749 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02482713 0,05890934 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02482713 0,0588513 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,02482713 0,05879337 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02482713 0,05873556 ! mannose metabolic process GO:0006013 13 9 0,000 0,02482713 0,05867786 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02482713 0,05862028 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02482713 0,05856281 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02482713 0,05850545 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02482713 0,05844821 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02482713 0,05839107 ! ruffle organization GO:0031529 15 9 0,000 0,02482713 0,05833405 ! retinol metabolic process GO:0042572 18 9 0,000 0,02482713 0,05827714 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02482713 0,05822034 ! behavioral fear response GO:0001662 22 9 0,000 0,02482713 0,05816365 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02482713 0,05810707 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02482713 0,0580506 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02482713 0,05799424 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,02482713 0,05793799 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02482713 0,05788185 ! segment specification GO:0007379 13 9 0,000 0,02482713 0,05782581 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02482713 0,05776989 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02482713 0,05771407 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02482713 0,05765836 ! response to amine stimulus GO:0014075 13 9 0,000 0,02482713 0,05760276 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02482713 0,05754727 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02482713 0,05749188 ! erythrocyte development GO:0048821 15 9 0,000 0,02482713 0,0574366 ! gas homeostasis GO:0033483 16 9 0,000 0,02482713 0,05738143 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02482713 0,05732636 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02482713 0,0572714 ! renal water homeostasis GO:0003091 14 9 0,000 0,02482713 0,05721654 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02482713 0,05716179 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02482713 0,05710714 ! icosanoid secretion GO:0032309 15 9 0,000 0,02482713 0,05705259 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02482713 0,05699815 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02482713 0,05694382 ! regulation of cell division GO:0051302 15 9 0,000 0,02482713 0,05688959 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02482713 0,05683546 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02482713 0,05678143 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02482713 0,05672751 ! sterol catabolic process GO:0016127 11 9 0,000 0,02482713 0,05667369 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02482713 0,05661997 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02482713 0,05656635 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02482713 0,05651283 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02482713 0,05645942 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02482713 0,05640611 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02482713 0,05635289 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02482713 0,05629978 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02482713 0,05624677 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02482713 0,05619385 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02482713 0,05614104 ! purine base metabolic process GO:0006144 21 9 0,000 0,02482713 0,05608832 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02482713 0,05603571 ! pigment granule transport GO:0051904 17 9 0,000 0,02482713 0,05598319 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02482713 0,05593077 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02482713 0,05587845 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02482713 0,05582623 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02482713 0,0557741 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02482713 0,05572208 ! mitochondrion localization GO:0051646 15 9 0,000 0,02482713 0,05567015 ! regulation of DNA binding GO:0051101 155 88 1,000 0,02520304 0,05646044 ! gland development GO:0048732 206 88 1,000 0,02520304 0,05640791 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,02573645 0,05754823 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,02573645 0,0574948 ! ossification GO:0001503 188 90 1,000 0,02627445 0,05864223 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 1,000 0,02627445 0,05858788 ! regulation of cell cycle process GO:0010564 149 90 1,000 0,02627445 0,05853363 ! bone development GO:0060348 189 91 1,000 0,02681701 0,05968707 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02754782 0,06125697 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 0,000 0,02754782 0,06120041 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02754782 0,06114395 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02754782 0,0610876 ! positive regulation of B cell proliferation GO:0030890 16 10 0,000 0,02754782 0,06103135 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02754782 0,0609752 ! synapsis GO:0007129 13 10 0,000 0,02754782 0,06091916 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02754782 0,06086322 ! N-glycan processing GO:0006491 20 10 0,000 0,02754782 0,06080738 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02754782 0,06075165 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02754782 0,06069601 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02754782 0,06064048 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02754782 0,06058505 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02754782 0,06052972 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02754782 0,06047449 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02754782 0,06041937 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02754782 0,06036434 ! androgen metabolic process GO:0008209 17 10 0,000 0,02754782 0,06030941 ! phospholipid efflux GO:0033700 16 10 0,000 0,02754782 0,06025459 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02754782 0,06019986 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02754782 0,06014523 ! pathogenesis GO:0009405 13 10 0,000 0,02754782 0,0600907 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02754782 0,06003627 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02754782 0,05998194 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02754782 0,05992771 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02754782 0,05987357 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02754782 0,05981954 ! endoderm development GO:0007492 16 10 0,000 0,02754782 0,0597656 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02754782 0,05971175 ! arginine catabolic process GO:0006527 13 10 0,000 0,02754782 0,05965801 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02754782 0,05960436 ! proline metabolic process GO:0006560 13 10 0,000 0,02754782 0,0595508 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02754782 0,05949735 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02754782 0,05944399 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02754782 0,05939072 ! V(D)J recombination GO:0033151 28 10 0,000 0,02754782 0,05933755 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02754782 0,05928448 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02754782 0,0592315 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02754782 0,05917861 ! B cell proliferation GO:0042100 18 10 0,000 0,02754782 0,05912582 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02754782 0,05907312 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02754782 0,05902052 ! multicellular organism growth GO:0035264 18 10 0,000 0,02754782 0,05896801 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02754782 0,0589156 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02754782 0,05886327 ! epithelial cell development GO:0002064 20 10 0,000 0,02754782 0,05881104 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02754782 0,05875891 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02754782 0,05870686 ! macroautophagy GO:0016236 17 10 0,000 0,02754782 0,05865491 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02754782 0,05860305 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02754782 0,05855128 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02754782 0,0584996 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02754782 0,05844801 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02754782 0,05839652 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02754782 0,05834511 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02754782 0,0582938 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02754782 0,05824257 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02754782 0,05819144 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02754782 0,05814039 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02754782 0,05808943 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02754782 0,05803857 ! response to dsRNA GO:0043331 20 10 0,000 0,02754782 0,05798779 ! DNA ligation GO:0006266 19 10 0,000 0,02754782 0,0579371 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02754782 0,0578865 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02754782 0,05783599 ! melanosome localization GO:0032400 16 10 0,000 0,02754782 0,05778557 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02754782 0,05773523 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02754782 0,05768498 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02754782 0,05763482 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02754782 0,05758475 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02754782 0,05753476 ! mRNA cleavage GO:0006379 17 10 0,000 0,02754782 0,05748486 ! protein sumoylation GO:0016925 15 10 0,000 0,02754782 0,05743505 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02754782 0,05738532 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02754782 0,05733568 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02754782 0,05728612 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02754782 0,05723665 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02754782 0,05718727 ! salivary gland development GO:0007431 27 10 0,000 0,02754782 0,05713797 ! prophase GO:0051324 15 10 0,000 0,02754782 0,05708876 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02754782 0,05703963 ! apical protein localization GO:0045176 15 10 0,000 0,02754782 0,05699058 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02754782 0,05694162 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02754782 0,05689274 ! midbrain development GO:0030901 13 10 0,000 0,02754782 0,05684395 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02754782 0,05679524 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02754782 0,05674661 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02754782 0,05669807 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02754782 0,05664961 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02754782 0,05660123 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02754782 0,05655294 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02754782 0,05650473 ! detection of calcium ion GO:0005513 23 10 0,000 0,02754782 0,0564566 ! oocyte development GO:0048599 17 10 0,000 0,02754782 0,05640855 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02754782 0,05636058 ! blastocyst formation GO:0001825 17 10 0,000 0,02754782 0,0563127 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02754782 0,05626489 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02754782 0,05621717 ! activation of innate immune response GO:0002218 12 10 0,000 0,02754782 0,05616953 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02754782 0,05612197 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02754782 0,05607449 ! response to nicotine GO:0035094 20 10 0,000 0,02754782 0,05602709 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02754782 0,05597977 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02754782 0,05593253 ! regulation of nucleotide metabolic process GO:0006140 182 93 1,000 0,02791569 0,05663165 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,02791569 0,05658395 ! regulation of membrane potential GO:0042391 164 93 1,000 0,02791569 0,05653632 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,02791569 0,05648877 ! regulation of T cell activation GO:0050863 158 94 1,000 0,02847175 0,05756557 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,03016649 0,06094087 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,030261 0,06108052 ! respiratory burst GO:0045730 17 11 0,000 0,030261 0,06102932 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,030261 0,06097821 ! neuron fate specification GO:0048665 17 11 0,000 0,030261 0,06092718 ! telencephalon cell migration GO:0022029 20 11 0,000 0,030261 0,06087624 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,030261 0,06082538 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,030261 0,06077461 ! thyroid gland development GO:0030878 26 11 0,000 0,030261 0,06072392 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,030261 0,06067331 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,030261 0,0606228 ! response to pain GO:0048265 24 11 0,000 0,030261 0,06057236 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,030261 0,06052201 ! T cell proliferation GO:0042098 26 11 0,000 0,030261 0,06047174 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,030261 0,06042156 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,030261 0,06037146 ! peptide or protein amino-terminal blocking GO:0018409 21 11 0,000 0,030261 0,06032144 ! ventral spinal cord development GO:0021517 21 11 0,000 0,030261 0,0602715 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,030261 0,06022165 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,030261 0,06017188 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,030261 0,06012219 ! melanocyte differentiation GO:0030318 21 11 0,000 0,030261 0,06007259 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,030261 0,06002307 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,030261 0,05997362 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,030261 0,05992426 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,030261 0,05987498 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,030261 0,05982578 ! lipid digestion GO:0044241 18 11 0,000 0,030261 0,05977666 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,030261 0,05972763 ! UV protection GO:0009650 19 11 0,000 0,030261 0,05967867 ! adult heart development GO:0007512 14 11 0,000 0,030261 0,05962979 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,030261 0,059581 ! temperature homeostasis GO:0001659 17 11 0,000 0,030261 0,05953228 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,030261 0,05948364 ! negative regulation of ossification GO:0030279 26 11 0,000 0,030261 0,05943508 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,030261 0,05938661 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,030261 0,05933821 ! regulation of organ growth GO:0046620 13 11 0,000 0,030261 0,05928988 ! pigment granule localization GO:0051875 20 11 0,000 0,030261 0,05924164 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,030261 0,05919348 ! vasoconstriction GO:0042310 18 11 0,000 0,030261 0,05914539 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,030261 0,05909738 ! embryonic axis specification GO:0000578 18 11 0,000 0,030261 0,05904945 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,030261 0,0590016 ! snRNA metabolic process GO:0016073 24 11 0,000 0,030261 0,05895383 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,030261 0,05890613 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,030261 0,05885851 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,030261 0,05881097 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,030261 0,0587635 ! zymogen activation GO:0031638 15 11 0,000 0,030261 0,05871611 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,030261 0,0586688 ! neuroblast proliferation GO:0007405 24 11 0,000 0,030261 0,05862156 ! nucleosome positioning GO:0016584 15 11 0,000 0,030261 0,0585744 ! regulation of isotype switching GO:0045191 22 11 0,000 0,030261 0,05852731 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,030261 0,0584803 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,030261 0,05843337 ! acid secretion GO:0046717 18 11 0,000 0,030261 0,05838651 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,030261 0,05833973 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,030261 0,05829302 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,030261 0,05824638 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,030261 0,05819982 ! oocyte differentiation GO:0009994 18 11 0,000 0,030261 0,05815334 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,030261 0,05810693 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,030261 0,05806059 ! cholesterol efflux GO:0033344 19 11 0,000 0,030261 0,05801433 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,030261 0,05796814 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,030261 0,05792202 ! germ cell migration GO:0008354 25 11 0,000 0,030261 0,05787598 ! embryonic gut development GO:0048566 15 11 0,000 0,030261 0,05783001 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,030261 0,05778411 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,030261 0,05773829 ! cardiac cell differentiation GO:0035051 31 11 0,000 0,030261 0,05769253 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,030261 0,05764686 ! defense response to fungus GO:0050832 13 11 0,000 0,030261 0,05760125 ! lysogeny GO:0030069 21 11 0,000 0,030261 0,05755571 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,030261 0,05751025 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,030261 0,05746486 ! sequestering of metal ion GO:0051238 14 11 0,000 0,030261 0,05741954 ! lamellipodium assembly GO:0030032 20 11 0,000 0,030261 0,05737429 ! nucleus localization GO:0051647 19 11 0,000 0,030261 0,05732912 ! regulation of synapse organization GO:0050807 17 11 0,000 0,030261 0,05728401 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 1,000 0,03131816 0,0592386 ! skeletal muscle tissue development GO:0007519 186 99 1,000 0,03131816 0,05919206 GO:0060538|skeletal muscle organ development, ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03296671 0,06225896 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03296671 0,06221013 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03296671 0,06216137 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03296671 0,0621127 ! regulation of B cell proliferation GO:0030888 20 12 0,000 0,03296671 0,0620641 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03296671 0,06201557 ! cartilage condensation GO:0001502 20 12 0,000 0,03296671 0,06196712 ! mating GO:0007618 17 12 0,000 0,03296671 0,06191875 ! protein complex disassembly GO:0043241 27 12 0,000 0,03296671 0,06187045 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,03296671 0,06182222 ! hippocampus development GO:0021766 26 12 0,000 0,03296671 0,06177408 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03296671 0,061726 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03296671 0,061678 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03296671 0,06163008 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03296671 0,06158223 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03296671 0,06153446 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03296671 0,06148675 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03296671 0,06143913 ! drug transport GO:0015893 16 12 0,000 0,03296671 0,06139157 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03296671 0,06134409 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03296671 0,06129669 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03296671 0,06124935 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03296671 0,06120209 ! focal adhesion formation GO:0048041 35 12 0,000 0,03296671 0,06115491 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03296671 0,06110779 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03296671 0,06106075 ! forebrain cell migration GO:0021885 21 12 0,000 0,03296671 0,06101378 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03296671 0,06096688 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03296671 0,06092006 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03296671 0,0608733 ! entry into host cell GO:0030260 32 12 0,000 0,03296671 0,06082662 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 26 12 0,000 0,03296671 0,06078001 ! monoamine transport GO:0015844 18 12 0,000 0,03296671 0,06073347 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03296671 0,060687 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03296671 0,06064061 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03296671 0,06059428 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03296671 0,06054803 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03296671 0,06050184 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03296671 0,06045573 ! protein homotetramerization GO:0051289 21 12 0,000 0,03296671 0,06040968 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03296671 0,06036371 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03296671 0,06031781 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03296671 0,06027197 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03296671 0,06022621 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03296671 0,06018051 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03296671 0,06013489 ! cranial nerve development GO:0021545 20 12 0,000 0,03296671 0,06008933 ! fucose catabolic process GO:0019317 22 12 0,000 0,03296671 0,06004384 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03296671 0,05999842 ! histone acetylation GO:0016573 26 12 0,000 0,03296671 0,05995307 ! histone methylation GO:0016571 26 12 0,000 0,03296671 0,05990779 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03296671 0,05986258 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03296671 0,05981743 ! gland morphogenesis GO:0022612 29 12 0,000 0,03296671 0,05977235 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03296671 0,05972734 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,03296671 0,0596824 ! T cell homeostasis GO:0043029 25 12 0,000 0,03296671 0,05963753 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03296671 0,05959272 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03296671 0,05954798 ! spleen development GO:0048536 22 12 0,000 0,03296671 0,05950331 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03296671 0,05945871 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03296671 0,05941417 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03296671 0,0593697 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03296671 0,05932529 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03296671 0,05928095 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03296671 0,05923668 ! response to cold GO:0009409 17 12 0,000 0,03296671 0,05919247 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03296671 0,05914833 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03296671 0,05910426 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03566496 0,06389419 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,03566496 0,06384665 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03566496 0,06379918 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03566496 0,06375178 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,03566496 0,06370446 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,03566496 0,0636572 ! lipid localization GO:0010876 28 13 0,000 0,03566496 0,06361001 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,03566496 0,06356289 ! organelle fusion GO:0048284 32 13 0,000 0,03566496 0,06351584 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,03566496 0,06346886 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,03566496 0,06342195 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,03566496 0,06337511 ! endocrine pancreas development GO:0031018 22 13 0,000 0,03566496 0,06332834 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,03566496 0,06328164 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,03566496 0,063235 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,03566496 0,06318844 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03566496 0,06314194 ! methionine metabolic process GO:0006555 27 13 0,000 0,03566496 0,06309552 ! plasma membrane organization GO:0007009 24 13 0,000 0,03566496 0,06304916 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,03566496 0,06300286 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,03566496 0,06295664 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,03566496 0,06291049 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,03566496 0,0628644 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,03566496 0,06281838 ! response to X-ray GO:0010165 25 13 0,000 0,03566496 0,06277242 ! cytokine metabolic process GO:0042107 22 13 0,000 0,03566496 0,06272654 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,03566496 0,06268072 ! exocrine system development GO:0035272 32 13 0,000 0,03566496 0,06263496 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,03566496 0,06258928 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,03566496 0,06254366 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,03566496 0,06249811 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,03566496 0,06245262 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,03566496 0,0624072 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,03566496 0,06236185 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,03566496 0,06231656 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,03566496 0,06227134 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,03566496 0,06222618 ! regulation of cellular pH GO:0030641 22 13 0,000 0,03566496 0,06218109 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03566496 0,06213606 ! ribosome assembly GO:0042255 17 13 0,000 0,03566496 0,0620911 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,03566496 0,06204621 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,03566496 0,06200137 ! chromatin silencing GO:0006342 26 13 0,000 0,03566496 0,06195661 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,03566496 0,06191191 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03566496 0,06186727 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03566496 0,0618227 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,03566496 0,06177819 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,03566496 0,06173374 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03566496 0,06168936 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,03566496 0,06164504 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,03566496 0,06160079 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,03566496 0,0615566 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,03566496 0,06151247 ! embryonic placenta development GO:0001892 23 13 0,000 0,03566496 0,06146841 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,03566496 0,06142441 ! insulin secretion GO:0030073 23 13 0,000 0,03566496 0,06138047 ! actin filament polymerization GO:0030041 24 13 0,000 0,03566496 0,0613366 ! acrosome reaction GO:0007340 18 13 0,000 0,03566496 0,06129279 ! rRNA transcription GO:0009303 25 14 0,000 0,03835577 0,06587009 ! lactation GO:0007595 26 14 0,000 0,03835577 0,0658231 ! N-terminal protein amino acid modification GO:0031365 27 14 0,000 0,03835577 0,06577619 ! reproductive cellular process GO:0048610 20 14 0,000 0,03835577 0,06572934 ! tRNA modification GO:0006400 20 14 0,000 0,03835577 0,06568256 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03835577 0,06563584 ! regulation of S phase GO:0033261 23 14 0,000 0,03835577 0,06558919 ! water transport GO:0006833 21 14 0,000 0,03835577 0,06554261 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,03835577 0,06549609 ! non-recombinational repair GO:0000726 25 14 0,000 0,03835577 0,06544964 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03835577 0,06540325 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03835577 0,06535693 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03835577 0,06531068 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,03835577 0,06526449 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03835577 0,06521837 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03835577 0,06517231 ! palate development GO:0060021 31 14 0,000 0,03835577 0,06512632 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03835577 0,06508039 ! regulation of mRNA processing GO:0050684 24 14 0,000 0,03835577 0,06503452 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,03835577 0,06498873 ! arginine metabolic process GO:0006525 17 14 0,000 0,03835577 0,06494299 ! regulation of heart rate GO:0002027 24 14 0,000 0,03835577 0,06489732 ! organic alcohol transport GO:0015850 29 14 0,000 0,03835577 0,06485171 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,03835577 0,06480617 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,03835577 0,0647607 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03835577 0,06471528 ! neutral amino acid transport GO:0015804 26 14 0,000 0,03835577 0,06466993 ! L-amino acid transport GO:0015807 30 14 0,000 0,03835577 0,06462464 ! bone mineralization GO:0030282 17 14 0,000 0,03835577 0,06457942 ! stem cell development GO:0048864 43 14 0,000 0,03835577 0,06453426 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,03835577 0,06448916 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,03835577 0,06444413 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03835577 0,06439916 ! cerebellum development GO:0021549 21 14 0,000 0,03835577 0,06435425 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,03835577 0,0643094 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,03835577 0,06426462 ! response to gamma radiation GO:0010332 28 14 0,000 0,03835577 0,0642199 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,03835577 0,06417524 ! cofactor transport GO:0051181 26 14 0,000 0,03835577 0,06413064 ! NADP metabolic process GO:0006739 24 14 0,000 0,03835577 0,0640861 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,03835577 0,06404163 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03835577 0,06399722 ! intestinal absorption GO:0050892 25 14 0,000 0,03835577 0,06395287 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,03835577 0,06390858 ! oxygen transport GO:0015671 21 14 0,000 0,03835577 0,06386435 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03835577 0,06382019 ! male genitalia development GO:0030539 24 14 0,000 0,03835577 0,06377608 ! regulation of axon extension GO:0030516 37 14 0,000 0,03835577 0,06373204 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,03835577 0,06368805 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03835577 0,06364413 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04103916 0,06804978 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04103916 0,06800291 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! superoxide anion generation GO:0042554 20 15 0,000 0,04103916 0,06795611 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,04103916 0,06790937 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,04103916 0,0678627 ! copper ion transport GO:0006825 20 15 0,000 0,04103916 0,06781609 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,04103916 0,06776955 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,04103916 0,06772307 ! sulfate transport GO:0008272 23 15 0,000 0,04103916 0,06767665 ! response to cAMP GO:0051591 22 15 0,000 0,04103916 0,06763029 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,04103916 0,067584 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,04103916 0,06753778 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,04103916 0,06749161 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,04103916 0,06744551 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,04103916 0,06739947 ! response to hexose stimulus GO:0009746 22 15 0,000 0,04103916 0,0673535 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,04103916 0,06730759 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,04103916 0,06726174 ! pituitary gland development GO:0021983 29 15 0,000 0,04103916 0,06721595 ! vesicle coating GO:0006901 33 15 0,000 0,04103916 0,06717022 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,04103916 0,06712456 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,04103916 0,06707896 ! regulation of exocytosis GO:0017157 22 15 0,000 0,04103916 0,06703342 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,04103916 0,06698794 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,04103916 0,06694253 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,04103916 0,06689717 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,04103916 0,06685188 ! regulation of vasodilation GO:0042312 26 15 0,000 0,04103916 0,06680665 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,04103916 0,06676148 ! histone deacetylation GO:0016575 20 15 0,000 0,04103916 0,06671637 ! mRNA splice site selection GO:0006376 38 15 0,000 0,04103916 0,06667132 ! tissue regeneration GO:0042246 26 15 0,000 0,04103916 0,06662634 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04103916 0,06658141 ! water homeostasis GO:0030104 27 15 0,000 0,04103916 0,06653654 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04103916 0,06649174 ! muscle maintenance GO:0046716 26 15 0,000 0,04103916 0,06644699 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,04103916 0,06640231 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,04103916 0,06635768 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,04103916 0,06631312 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04103916 0,06626861 ! heme biosynthetic process GO:0006783 29 15 0,000 0,04103916 0,06622416 ! cell killing GO:0001906 29 15 0,000 0,04103916 0,06617978 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,04103916 0,06613545 ! detection of bacterium GO:0016045 18 15 0,000 0,04103916 0,06609118 ! epithelial to mesenchymal transition GO:0001837 28 15 0,000 0,04103916 0,06604698 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,04103916 0,06600283 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,04103916 0,06595874 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,04103916 0,06591471 ! peptide hormone processing GO:0016486 23 15 0,000 0,04103916 0,06587073 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04371516 0,07011911 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,04371516 0,0700724 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04371516 0,07002574 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,04371516 0,06997915 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,04371516 0,06993262 ! bone remodeling GO:0046849 27 16 0,000 0,04371516 0,06988616 ! filopodium assembly GO:0046847 32 16 0,000 0,04371516 0,06983975 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 0,000 0,04371516 0,06979341 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04371516 0,06974713 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04371516 0,0697009 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04371516 0,06965475 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,04371516 0,06960865 ! startle response GO:0001964 28 16 0,000 0,04371516 0,06956261 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,04371516 0,06951663 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,04371516 0,06947072 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,04371516 0,06942486 ! activation of MAPKK activity GO:0000186 35 16 0,000 0,04371516 0,06937907 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04371516 0,06933333 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,04371516 0,06928766 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04371516 0,06924204 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04371516 0,06919649 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04371516 0,069151 ! response to osmotic stress GO:0006970 25 16 0,000 0,04371516 0,06910556 ! lysosomal transport GO:0007041 26 16 0,000 0,04371516 0,06906019 ! fructose metabolic process GO:0006000 25 16 0,000 0,04371516 0,06901487 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04371516 0,06896962 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04371516 0,06892442 ! intermediate filament-based process GO:0045103 32 16 0,000 0,04371516 0,06887928 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,04371516 0,06883421 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04371516 0,06878919 ! axon cargo transport GO:0008088 43 16 0,000 0,04371516 0,06874423 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,04371516 0,06869932 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,04371516 0,06865448 ! DNA replication initiation GO:0006270 27 16 0,000 0,04371516 0,0686097 ! neuron recognition GO:0008038 35 16 0,000 0,04371516 0,06856497 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,04371516 0,0685203 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,04371516 0,06847569 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,04371516 0,06843114 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,04371516 0,06838665 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04371516 0,06834221 GO:0046466|membrane lipid catabolic process, ! biomineral formation GO:0031214 20 16 0,000 0,04371516 0,06829783 ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04371516 0,06825351 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04371516 0,06820925 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04371516 0,06816505 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04371516 0,0681209 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,04371516 0,06807681 ! defense response to virus GO:0051607 37 16 0,000 0,04371516 0,06803277 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,04638377 0,0721392 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,04638377 0,0720926 ! metencephalon development GO:0022037 30 17 0,000 0,04638377 0,07204606 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,04638377 0,07199958 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,04638377 0,07195316 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,04638377 0,0719068 ! endothelial cell migration GO:0043542 28 17 0,000 0,04638377 0,0718605 ! inositol metabolic process GO:0006020 28 17 0,000 0,04638377 0,07181425 ! gene silencing by RNA GO:0031047 36 17 0,000 0,04638377 0,07176807 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,04638377 0,07172195 ! glial cell development GO:0021782 27 17 0,000 0,04638377 0,07167588 ! limbic system development GO:0021761 36 17 0,000 0,04638377 0,07162988 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,04638377 0,07158393 ! adult walking behavior GO:0007628 33 17 0,000 0,04638377 0,07153804 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,04638377 0,07149222 ! heart looping GO:0001947 30 17 0,000 0,04638377 0,07144645 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,04638377 0,07140074 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,04638377 0,07135508 ! myoblast differentiation GO:0045445 45 17 0,000 0,04638377 0,07130949 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,04638377 0,07126395 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,04638377 0,07121847 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,04638377 0,07117305 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,04638377 0,07112769 ! glycine metabolic process GO:0006544 28 17 0,000 0,04638377 0,07108239 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,04638377 0,07103714 ! NAD metabolic process GO:0019674 29 17 0,000 0,04638377 0,07099195 ! membrane budding GO:0006900 37 17 0,000 0,04638377 0,07094682 ! DNA integration GO:0015074 29 17 0,000 0,04638377 0,07090175 ! regulation of protein binding GO:0043393 33 17 0,000 0,04638377 0,07085673 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,04638377 0,07081177 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,04638377 0,07076687 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,04638377 0,07072202 ! genitalia development GO:0048806 30 17 0,000 0,04638377 0,07067723 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,04638377 0,0706325 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,04638377 0,07058782 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,04638377 0,0705432 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,04638377 0,07049864 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,04638377 0,07045413 ! steroid catabolic process GO:0006706 31 17 0,000 0,04638377 0,07040968 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,04638377 0,07036529 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,04638377 0,07032095 ! gas transport GO:0015669 25 17 0,000 0,04638377 0,07027667 ! organic cation transport GO:0015695 31 17 0,000 0,04638377 0,07023244 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,04638377 0,07018827 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,04638377 0,07014415 ! microspike assembly GO:0030035 36 17 0,000 0,04638377 0,07010009 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,04638377 0,07005609 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,04904502 0,07402906 ! neuron maturation GO:0042551 42 18 0,000 0,04904502 0,07398265 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,04904502 0,0739363 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,04904502 0,07389 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,04904502 0,07384376 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,04904502 0,07379758 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,04904502 0,07375145 ! memory GO:0007613 31 18 0,000 0,04904502 0,07370539 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04904502 0,07365938 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,04904502 0,07361343 ! patterning of blood vessels GO:0001569 39 18 0,000 0,04904502 0,07356754 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,04904502 0,0735217 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,04904502 0,07347592 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,04904502 0,0734302 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,04904502 0,07338453 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04904502 0,07333892 ! response to retinoic acid GO:0032526 26 18 0,000 0,04904502 0,07329337 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,04904502 0,07324788 ! response to fungus GO:0009620 21 18 0,000 0,04904502 0,07320244 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,04904502 0,07315705 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,04904502 0,07311173 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,04904502 0,07306646 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,04904502 0,07302124 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,04904502 0,07297608 ! vitamin transport GO:0051180 27 18 0,000 0,04904502 0,07293098 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,04904502 0,07288593 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,04904502 0,07284094 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,04904502 0,07279601 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,04904502 0,07275113 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,04904502 0,0727063 ! nerve development GO:0021675 28 18 0,000 0,04904502 0,07266153 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,04904502 0,07261682 ! protein secretion GO:0009306 39 19 0,000 0,05169894 0,07649917 ! negative regulation of defense response GO:0031348 25 19 0,000 0,05169894 0,07645215 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,05169894 0,07640519 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,05169894 0,07635829 ! skin development GO:0043588 36 19 0,000 0,05169894 0,07631144 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,05169894 0,07626465 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05169894 0,07621792 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,05169894 0,07617125 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,05169894 0,07612463 ! bile acid metabolic process GO:0008206 29 19 0,000 0,05169894 0,07607807 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,05169894 0,07603157 ! cerebral cortex development GO:0021987 36 19 0,000 0,05169894 0,07598512 ! pigmentation during development GO:0048066 41 19 0,000 0,05169894 0,07593874 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,05169894 0,0758924 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,05169894 0,07584613 ! heme metabolic process GO:0042168 36 19 0,000 0,05169894 0,07579991 ! actin filament bundle formation GO:0051017 42 19 0,000 0,05169894 0,07575375 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,05169894 0,07570764 ! plasma membrane fusion GO:0045026 28 19 0,000 0,05169894 0,07566159 ! peptide cross-linking GO:0018149 37 19 0,000 0,05169894 0,07561559 ! protein export from nucleus GO:0006611 36 19 0,000 0,05169894 0,07556965 ! heart process GO:0003015 30 19 0,000 0,05169894 0,07552377 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,05169894 0,07547794 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,05169894 0,07543217 ! visual learning GO:0008542 36 19 0,000 0,05169894 0,07538645 ! cellular pigmentation GO:0033059 36 19 0,000 0,05169894 0,07534079 ! G1 phase GO:0051318 40 19 0,000 0,05169894 0,07529519 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,05169894 0,07524964 ! cell-cell junction organization GO:0045216 35 19 0,000 0,05169894 0,07520414 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,05169894 0,0751587 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,05169894 0,07511331 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,05169894 0,07506798 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,05169894 0,07502271 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,05169894 0,07497749 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,05169894 0,07493232 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,05169894 0,07488721 ! cilium assembly GO:0042384 37 19 0,000 0,05169894 0,07484215 ! peptide hormone secretion GO:0030072 31 19 0,000 0,05169894 0,07479714 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,05434554 0,07857894 ! positive regulation of ossification GO:0045778 47 20 0,000 0,05434554 0,07853175 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,05434554 0,07848461 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,05434554 0,07843753 ! protein amino acid acetylation GO:0006473 39 20 0,000 0,05434554 0,07839051 ! cAMP metabolic process GO:0046058 36 20 0,000 0,05434554 0,07834354 ! response to vitamin GO:0033273 31 20 0,000 0,05434554 0,07829662 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,05434554 0,07824977 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,05434554 0,07820297 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,05434554 0,07815622 ! response to alkaloid GO:0043279 38 20 0,000 0,05434554 0,07810954 ! retinoid metabolic process GO:0001523 32 20 0,000 0,05434554 0,0780629 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,05434554 0,07801633 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,05434554 0,0779698 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,05434554 0,07792334 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,05434554 0,07787693 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,05434554 0,07783057 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,05434554 0,07778427 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,05434554 0,07773803 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,05434554 0,07769184 ! body fluid secretion GO:0007589 31 20 0,000 0,05434554 0,0776457 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,05434554 0,07759962 ! peptide secretion GO:0002790 35 20 0,000 0,05434554 0,0775536 ! stem cell differentiation GO:0048863 53 20 0,000 0,05434554 0,07750762 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,05434554 0,07746171 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,05434554 0,07741585 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,05434554 0,07737004 ! sensory perception of pain GO:0019233 30 20 0,000 0,05434554 0,07732428 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,05434554 0,07727858 ! diencephalon development GO:0021536 34 20 0,000 0,05434554 0,07723294 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,05434554 0,07718735 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,05434554 0,07714181 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,05434554 0,07709632 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,05434554 0,07705089 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,05434554 0,07700551 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,05434554 0,07696019 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,05434554 0,07691492 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,05434554 0,0768697 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,05434554 0,07682454 ! actin filament-based movement GO:0030048 43 20 0,000 0,05434554 0,07677943 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,05434554 0,07673437 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,05434554 0,07668936 ! negative regulation of translation GO:0017148 29 20 0,000 0,05434554 0,07664441 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,05434554 0,07659951 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,05434554 0,07655466 ! regulation of cell killing GO:0031341 42 21 0,000 0,05698484 0,08022558 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,05698484 0,08017866 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,05698484 0,0801318 ! hormone secretion GO:0046879 38 21 0,000 0,05698484 0,080085 ! glycerol metabolic process GO:0006071 34 21 0,000 0,05698484 0,08003825 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,05698484 0,07999155 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,05698484 0,07994491 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,05698484 0,07989832 ! axis specification GO:0009798 38 21 0,000 0,05698484 0,07985179 ! ovarian follicle development GO:0001541 35 21 0,000 0,05698484 0,07980531 ! smooth muscle contraction GO:0006939 46 21 0,000 0,05698484 0,07975888 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,05698484 0,07971251 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,05698484 0,07966619 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,05698484 0,07961993 ! cell aging GO:0007569 44 21 0,000 0,05698484 0,07957372 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,05698484 0,07952756 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,05698484 0,07948146 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,05698484 0,07943541 ! cytolysis GO:0019835 24 21 0,000 0,05698484 0,07938941 ! vasodilation GO:0042311 39 21 0,000 0,05698484 0,07934347 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,05698484 0,07929758 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,05698484 0,07925174 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,05698484 0,07920596 ! oogenesis GO:0048477 36 21 0,000 0,05698484 0,07916023 ! DNA modification GO:0006304 34 21 0,000 0,05698484 0,07911455 ! collagen fibril organization GO:0030199 59 21 0,000 0,05698484 0,07906892 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,05698484 0,07902335 ! negative regulation of intracellular transport GO:0032387 41 21 0,000 0,05698484 0,07897783 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,05698484 0,07893236 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,05698484 0,07888695 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,05698484 0,07884158 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,05698484 0,07879627 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,05698484 0,07875101 ! collagen catabolic process GO:0030574 28 21 0,000 0,05698484 0,07870581 ! sperm-egg recognition GO:0035036 21 21 0,000 0,05698484 0,07866065 ! gut development GO:0048565 39 21 0,000 0,05698484 0,07861555 ! positive regulation of protein catabolic process GO:0045732 38 22 0,000 0,05961686 0,08219952 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,05961686 0,08215244 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,05961686 0,08210541 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,05961686 0,08205844 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,05961686 0,08201152 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,05961686 0,08196466 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,05961686 0,08191785 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,05961686 0,08187109 ! regeneration GO:0031099 41 22 0,000 0,05961686 0,08182439 ! keratinization GO:0031424 28 22 0,000 0,05961686 0,08177774 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,05961686 0,08173114 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,05961686 0,0816846 ! sensory perception of taste GO:0050909 28 22 0,000 0,05961686 0,08163811 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,05961686 0,08159167 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,05961686 0,08154528 ! vacuolar transport GO:0007034 36 22 0,000 0,05961686 0,08149895 ! lysosome organization GO:0007040 41 22 0,000 0,05961686 0,08145267 ! central nervous system neuron development GO:0021954 46 22 0,000 0,05961686 0,08140644 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,05961686 0,08136027 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,05961686 0,08131415 ! fucose metabolic process GO:0006004 39 22 0,000 0,05961686 0,08126808 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,05961686 0,08122206 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,05961686 0,08117609 ! ureteric bud development GO:0001657 43 22 0,000 0,05961686 0,08113018 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,05961686 0,08108432 GO:0060415|muscle tissue morphogenesis, ! renal system process GO:0003014 41 22 0,000 0,05961686 0,08103851 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,05961686 0,08099275 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,05961686 0,08094704 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,05961686 0,08090139 ! sarcomere organization GO:0045214 30 22 0,000 0,05961686 0,08085578 ! positive regulation of B cell activation GO:0050871 38 22 0,000 0,05961686 0,08081023 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,05961686 0,08076473 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,05961686 0,08071928 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,05961686 0,08067388 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,06224162 0,08417838 ! myeloid leukocyte differentiation GO:0002573 40 23 0,000 0,06224162 0,08413108 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,06224162 0,08408385 ! viral genome replication GO:0019079 41 23 0,000 0,06224162 0,08403666 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,06224162 0,08398953 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,06224162 0,08394245 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,06224162 0,08389542 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,06224162 0,08384845 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,06224162 0,08380153 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,06224162 0,08375466 ! visual behavior GO:0007632 42 23 0,000 0,06224162 0,08370784 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,06224162 0,08366108 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,06224162 0,08361437 ! response to ethanol GO:0045471 46 23 0,000 0,06224162 0,08356771 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,06224162 0,0835211 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,06224162 0,08347454 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,06224162 0,08342804 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,06224162 0,08338159 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,06224162 0,08333519 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,06224162 0,08328884 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,06224162 0,08324254 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,06224162 0,08319629 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,06224162 0,0831501 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,06224162 0,08310396 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,06224162 0,08305787 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,06224162 0,08301182 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,06224162 0,08296583 ! fatty acid transport GO:0015908 44 23 0,000 0,06224162 0,0829199 ! platelet activation GO:0030168 37 23 0,000 0,06224162 0,08287401 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,06224162 0,08282817 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,06224162 0,08278238 ! hormone transport GO:0009914 40 23 0,000 0,06224162 0,08273665 ! cell-cell recognition GO:0009988 25 23 0,000 0,06224162 0,08269096 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,06224162 0,08264533 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,06224162 0,08259974 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,06224162 0,08255421 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,06224162 0,08250872 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,06485914 0,08593122 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,06485914 0,08588392 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,06485914 0,08583668 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,06485914 0,08578949 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,06485914 0,08574236 ! vesicle docking GO:0048278 47 24 0,000 0,06485914 0,08569527 ! spinal cord development GO:0021510 47 24 0,000 0,06485914 0,08564824 ! vacuole organization GO:0007033 43 24 0,000 0,06485914 0,08560126 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,06485914 0,08555432 ! digestive system process GO:0022600 39 24 0,000 0,06485914 0,08550745 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,06485914 0,08546062 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,06485914 0,08541384 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,06485914 0,08536712 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,06485914 0,08532044 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,06485914 0,08527382 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,06485914 0,08522725 ! membrane depolarization GO:0051899 39 24 0,000 0,06485914 0,08518073 ! pallium development GO:0021543 49 24 0,000 0,06485914 0,08513425 ! pentose metabolic process GO:0019321 35 24 0,000 0,06485914 0,08508783 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,06485914 0,08504147 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,06485914 0,08499515 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,06485914 0,08494888 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,06485914 0,08490266 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,06485914 0,08485649 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,06485914 0,08481037 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,06485914 0,08476431 ! regulation of amine transport GO:0051952 40 24 0,000 0,06485914 0,08471829 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,06746944 0,08808002 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 0,000 0,06746944 0,08803225 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,06746944 0,08798454 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,06746944 0,08793688 ! phototransduction GO:0007602 33 25 0,000 0,06746944 0,08788927 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,06746944 0,08784171 GO:0006479|protein amino acid methylation, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,06746944 0,0877942 ! sperm motility GO:0030317 31 25 0,000 0,06746944 0,08774674 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,06746944 0,08769934 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,06746944 0,08765199 ! response to starvation GO:0042594 42 25 0,000 0,06746944 0,08760468 ! osteoblast differentiation GO:0001649 60 25 0,000 0,06746944 0,08755743 ! neural crest cell development GO:0014032 54 25 0,000 0,06746944 0,08751023 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,06746944 0,08746308 ! negative regulation of cell development GO:0010721 73 25 0,000 0,06746944 0,08741598 GO:0050768|negative regulation of neurogenesis, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,06746944 0,08736893 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,06746944 0,08732193 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,06746944 0,08727499 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,06746944 0,08722809 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! somitogenesis GO:0001756 43 25 0,000 0,06746944 0,08718124 ! immunoglobulin production GO:0002377 55 25 0,000 0,06746944 0,08713445 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,06746944 0,0870877 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,06746944 0,08704101 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,06746944 0,08699436 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,06746944 0,08694776 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,06746944 0,08690122 ! telomere organization GO:0032200 43 25 0,000 0,06746944 0,08685472 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,06746944 0,08680828 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,06746944 0,08676188 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,07007254 0,09006119 ! embryonic pattern specification GO:0009880 44 26 0,000 0,07007254 0,0900131 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,07007254 0,08996507 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,07007254 0,08991709 ! initiation of viral infection GO:0019059 57 26 0,000 0,07007254 0,08986916 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,07007254 0,08982128 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,07007254 0,08977345 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,07007254 0,08972567 ! molting cycle process GO:0022404 50 26 0,000 0,07007254 0,08967795 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,07007254 0,08963027 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,07007254 0,08958265 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,07007254 0,08953507 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,07007254 0,08948755 GO:0051297|centrosome organization, ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,07007254 0,08944008 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,07007254 0,08939265 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,07007254 0,08934528 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,07007254 0,08929796 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,07007254 0,08925068 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,07007254 0,08920346 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,07007254 0,08915629 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,07007254 0,08910917 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,07007254 0,08906209 ! blastocyst development GO:0001824 49 26 0,000 0,07007254 0,08901507 ! leukocyte proliferation GO:0070661 52 26 0,000 0,07007254 0,0889681 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,07007254 0,08892117 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,07007254 0,0888743 ! neuron fate commitment GO:0048663 48 27 0,000 0,07266847 0,09211819 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,07266847 0,09206968 ! iron ion transport GO:0006826 59 27 0,000 0,07266847 0,09202123 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,07266847 0,09197282 ! protein amino acid acylation GO:0043543 55 27 0,000 0,07266847 0,09192446 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,07266847 0,09187616 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,07266847 0,09182791 ! fat cell differentiation GO:0045444 50 27 0,000 0,07266847 0,0917797 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,07266847 0,09173155 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,07266847 0,09168345 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,07266847 0,09163539 ! autophagy GO:0006914 41 27 0,000 0,07266847 0,09158739 ! male gonad development GO:0008584 44 27 0,000 0,07266847 0,09153944 ! response to toxin GO:0009636 47 27 0,000 0,07266847 0,09149154 ! primary neural tube formation GO:0014020 51 27 0,000 0,07266847 0,09144369 ! base-excision repair GO:0006284 41 27 0,000 0,07266847 0,09139589 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,07266847 0,09134814 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,07266847 0,09130043 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,07266847 0,09125278 ! glutathione metabolic process GO:0006749 39 27 0,000 0,07266847 0,09120518 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,07266847 0,09115763 ! negative regulation of neuron differentiation GO:0045665 42 27 0,000 0,07266847 0,09111013 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,07266847 0,09106267 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,07525723 0,09425762 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 0,000 0,07525723 0,09420858 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,07525723 0,09415959 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,07525723 0,09411065 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,07525723 0,09406176 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,07525723 0,09401292 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,07525723 0,09396414 ! synaptogenesis GO:0007416 42 28 0,000 0,07525723 0,0939154 ! lipid oxidation GO:0034440 43 28 0,000 0,07525723 0,09386671 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,07525723 0,09381808 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,07525723 0,09376949 ! translational initiation GO:0006413 65 29 0,000 0,07783885 0,09693596 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,07783885 0,09688581 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,07783885 0,09683571 ! regulation of pH GO:0006885 43 29 0,000 0,07783885 0,09678567 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,07783885 0,09673568 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,07783885 0,09668574 ! catechol metabolic process GO:0009712 54 29 0,000 0,07783885 0,09663585 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,07783885 0,09658601 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,07783885 0,09653622 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,07783885 0,09648649 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,07783885 0,0964368 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,07783885 0,09638717 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,07783885 0,09633759 ! cell fate determination GO:0001709 60 29 0,000 0,07783885 0,09628806 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,07783885 0,09623858 ! detection of light stimulus GO:0009583 38 29 0,000 0,07783885 0,09618915 ! cellular response to extracellular stimulus GO:0031668 48 29 0,000 0,07783885 0,09613977 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,07783885 0,09609044 ! tissue homeostasis GO:0001894 48 29 0,000 0,07783885 0,09604117 GO:0048871|multicellular organismal homeostasis, ! regulation of coagulation GO:0050818 46 29 0,000 0,07783885 0,09599194 ! phenol metabolic process GO:0018958 55 30 0,000 0,08041335 0,09911604 ! zinc ion transport GO:0006829 45 30 0,000 0,08041335 0,09906529 ! membrane docking GO:0022406 61 30 0,000 0,08041335 0,09901459 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,08041335 0,09896395 ! cell junction assembly GO:0034329 78 30 0,000 0,08041335 0,09891335 ! regulation of innate immune response GO:0045088 51 30 0,000 0,08041335 0,09886281 ! acute-phase response GO:0006953 49 30 0,000 0,08041335 0,09881232 ! myofibril assembly GO:0030239 47 30 0,000 0,08041335 0,09876188 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,08041335 0,09871149 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,08041335 0,09866115 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,08041335 0,09861087 ! phospholipid transport GO:0015914 51 30 0,000 0,08041335 0,09856063 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,08041335 0,09851045 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,08041335 0,09846031 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,08041335 0,09841023 ! eye morphogenesis GO:0048592 60 30 0,000 0,08041335 0,0983602 ! regulation of B cell activation GO:0050864 50 30 0,000 0,08041335 0,09831022 ! response to heat GO:0009408 50 30 0,000 0,08041335 0,09826029 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,08298075 0,10134603 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,08298075 0,10129461 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,08298075 0,10124324 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,08298075 0,10119193 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,08298075 0,10114067 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,08298075 0,10108946 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,08298075 0,1010383 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,08298075 0,10098719 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,08298075 0,10093614 ! ovulation cycle process GO:0022602 49 31 0,000 0,08298075 0,10088513 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,08298075 0,10083418 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,08298075 0,10078328 ! peptide transport GO:0015833 55 31 0,000 0,08298075 0,10073243 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,08298075 0,10068163 ! iron ion homeostasis GO:0055072 54 31 0,000 0,08298075 0,10063088 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,08298075 0,10058019 ! mesoderm formation GO:0001707 69 31 0,000 0,08298075 0,10052954 ! natural killer cell activation GO:0030101 45 31 0,000 0,08298075 0,10047895 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,08298075 0,10042841 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,08298075 0,10037792 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,08298075 0,10032748 ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,08298075 0,10027708 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,08554106 0,10331917 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,08554106 0,10326733 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,08554106 0,10321554 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,08554106 0,10316381 ! cholesterol transport GO:0030301 56 32 0,000 0,08554106 0,10311212 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,08554106 0,10306049 ! spliceosome assembly GO:0000245 67 32 0,000 0,08554106 0,1030089 ! spindle organization GO:0007051 46 32 0,000 0,08554106 0,10295737 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,08554106 0,1029059 ! metanephros development GO:0001656 74 32 0,000 0,08554106 0,10285447 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,08554106 0,10280309 ! response to ionizing radiation GO:0010212 65 32 0,000 0,08554106 0,10275177 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,08554106 0,10270049 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,08554106 0,10264927 ! muscle cell development GO:0055001 49 32 0,000 0,08554106 0,1025981 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,08554106 0,10254698 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,08554106 0,10249591 ! ovulation cycle GO:0042698 51 32 0,000 0,08554106 0,10244489 ! BMP signaling pathway GO:0030509 64 32 0,000 0,08554106 0,10239393 ! hindbrain development GO:0030902 61 32 0,000 0,08554106 0,10234301 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,08554106 0,10229214 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,08554106 0,10224133 ! gene silencing GO:0016458 65 32 0,000 0,08554106 0,10219056 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,08809431 0,10518854 ! post-embryonic development GO:0009791 69 33 0,000 0,08809431 0,10513637 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,08809431 0,10508424 ! protein targeting to membrane GO:0006612 68 33 0,000 0,08809431 0,10503217 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,08809431 0,10498015 ! ceramide metabolic process GO:0006672 64 33 0,000 0,08809431 0,10492817 ! formation of primary germ layer GO:0001704 72 33 0,000 0,08809431 0,10487626 ! sterol transport GO:0015918 57 33 0,000 0,08809431 0,10482439 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,08809431 0,10477257 ! adult locomotory behavior GO:0008344 59 33 0,000 0,08809431 0,10472081 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,08809431 0,10466909 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,09064052 0,10764121 ! glial cell differentiation GO:0010001 63 34 0,000 0,09064052 0,1075881 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,09064052 0,10753505 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,09064052 0,10748205 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,09064052 0,10742911 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,09064052 0,10737621 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,09064052 0,10732337 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,09064052 0,10727058 ! mismatch repair GO:0006298 46 34 0,000 0,09064052 0,10721784 ! spermatid development GO:0007286 63 34 0,000 0,09064052 0,10716515 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,09064052 0,10711252 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,09064052 0,10705993 ! placenta development GO:0001890 53 34 0,000 0,09064052 0,1070074 ! regulation of muscle development GO:0048634 70 35 0,000 0,0931797 0,10995113 ! negative regulation of secretion GO:0051048 63 35 0,000 0,0931797 0,10989723 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,0931797 0,10984339 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,0931797 0,1097896 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,0931797 0,10973586 ! odontogenesis GO:0042476 66 35 0,000 0,0931797 0,10968217 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,0931797 0,10962854 ! female gonad development GO:0008585 58 35 0,000 0,0931797 0,10957495 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,0931797 0,10952143 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 0,000 0,0931797 0,10946795 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,0931797 0,10941452 ! cytokine production GO:0001816 59 35 0,000 0,0931797 0,10936115 ! neural tube formation GO:0001841 67 35 0,000 0,0931797 0,10930783 ! vesicle localization GO:0051648 64 35 0,000 0,0931797 0,10925456 ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,09571188 0,11216891 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,09571188 0,1121143 ! cell junction organization GO:0034330 86 36 0,000 0,09571188 0,11205974 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,09571188 0,11200524 ! positive regulation of cell development GO:0010720 80 36 0,000 0,09571188 0,11195079 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,09571188 0,11189639 ! regulation of proteolysis GO:0030162 72 36 0,000 0,09571188 0,11184205 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,09571188 0,11178775 ! aerobic respiration GO:0009060 55 36 0,000 0,09571188 0,11173351 ! androgen receptor signaling pathway GO:0030521 74 36 0,000 0,09571188 0,11167933 ! embryonic organ development GO:0048568 57 36 0,000 0,09571188 0,11162519 ! RNA export from nucleus GO:0006405 56 37 0,000 0,09823706 0,11451472 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,09823706 0,11445926 ! meiosis I GO:0007127 65 37 0,000 0,09823706 0,11440386 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,09823706 0,11434851 ! actomyosin structure organization GO:0031032 62 37 0,000 0,09823706 0,11429322 ! organic anion transport GO:0015711 68 37 0,000 0,09823706 0,11423798 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,09823706 0,11418279 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,09823706 0,11412766 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,09823706 0,11407258 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,09823706 0,11401755 GO:0015986|ATP synthesis coupled proton transport, ! pigment metabolic process GO:0042440 80 37 0,000 0,09823706 0,11396257 ! spermatid differentiation GO:0048515 66 37 0,000 0,09823706 0,11390765 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,10075528 0,1167713 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,10075528 0,11671508 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,10075528 0,11665891 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,10075528 0,1166028 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,10075528 0,11654674 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,10075528 0,11649073 ! lipid homeostasis GO:0055088 67 38 0,000 0,10075528 0,11643478 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,10075528 0,11637888 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,10075528 0,11632304 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,10075528 0,11626725 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,10075528 0,11621151 ! positive regulation of leukocyte proliferation GO:0070665 62 38 0,000 0,10075528 0,11615583 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,10075528 0,1161002 ! mRNA catabolic process GO:0006402 71 39 0,000 0,10326656 0,11893697 ! learning GO:0007612 77 39 0,000 0,10326656 0,11888007 ! ear morphogenesis GO:0042471 60 39 0,000 0,10326656 0,11882321 ! organic ether metabolic process GO:0018904 55 39 0,000 0,10326656 0,11876641 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,10326656 0,11870967 ! segmentation GO:0035282 67 39 0,000 0,10326656 0,11865298 ! ion transmembrane transport GO:0034220 66 39 0,000 0,10326656 0,11859634 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,10326656 0,11853976 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,10326656 0,11848323 ! RNA modification GO:0009451 57 39 0,000 0,10326656 0,11842676 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,10326656 0,11837034 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,1057709 0,12118323 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,1057709 0,12112555 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,1057709 0,12106793 ! feeding behavior GO:0007631 59 40 0,000 0,1057709 0,12101036 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,1057709 0,12095284 ! mesenchymal cell development GO:0014031 87 40 0,000 0,1057709 0,12089538 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,1057709 0,12083798 ! cytokinesis GO:0000910 72 40 0,000 0,1057709 0,12078063 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,10826833 0,12357382 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,10826833 0,12351522 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,10826833 0,12345668 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,10826833 0,1233982 ! gliogenesis GO:0042063 88 41 0,000 0,10826833 0,12333977 ! T cell differentiation GO:0030217 81 41 0,000 0,10826833 0,1232814 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,10826833 0,12322309 ! female gamete generation GO:0007292 61 41 0,000 0,10826833 0,12316482 ! polyol metabolic process GO:0019751 66 41 0,000 0,10826833 0,12310662 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,10826833 0,12304847 ! positive regulation of transcription factor activity GO:0051091 62 42 0,000 0,11075887 0,12581957 GO:0090047|positive regulation of transcription regulator activity, ! response to reactive oxygen species GO:0000302 67 42 0,000 0,11075887 0,12576019 ! regulation of tube size GO:0035150 71 42 0,000 0,11075887 0,12570087 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,11075887 0,1256416 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,11075887 0,12558239 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,11075887 0,12552324 ! neuron migration GO:0001764 79 42 0,000 0,11075887 0,12546414 ! regulation of protein secretion GO:0050708 71 42 0,000 0,11075887 0,1254051 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,11075887 0,12534612 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,11324254 0,12809663 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,11324254 0,12803644 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,11324254 0,1279763 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,11324254 0,12791622 ! glucose transport GO:0015758 65 43 0,000 0,11324254 0,12785619 ! striated muscle cell differentiation GO:0051146 82 43 0,000 0,11324254 0,12779622 ! neural tube development GO:0021915 77 43 0,000 0,11324254 0,12773631 ! striated muscle contraction GO:0006941 77 43 0,000 0,11324254 0,12767645 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,11324254 0,12761665 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,11571935 0,13034679 ! hexose transport GO:0008645 67 44 0,000 0,11571935 0,1302858 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,11571935 0,13022486 ! male sex differentiation GO:0046661 76 44 0,000 0,11571935 0,13016398 ! double-strand break repair GO:0006302 81 44 0,000 0,11571935 0,13010315 ! biopolymer methylation GO:0043414 84 44 0,000 0,11571935 0,13004239 ! B cell differentiation GO:0030183 107 44 0,000 0,11571935 0,12998168 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,11571935 0,12992102 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,11571935 0,12986042 ! developmental growth GO:0048589 82 44 0,000 0,11571935 0,12979988 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,11818932 0,13250863 ! glycolysis GO:0006096 65 45 0,000 0,11818932 0,13244691 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,11818932 0,13238525 ! detection of stimulus involved in sensory perception GO:0050906 66 45 0,000 0,11818932 0,13232364 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,11818932 0,1322621 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,11818932 0,13220061 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,11818932 0,13213918 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,11818932 0,1320778 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,11818932 0,13201649 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,11818932 0,13195523 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,12065248 0,1346428 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,12065248 0,13458038 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,12065248 0,13451801 ! pigmentation GO:0043473 100 46 0,000 0,12065248 0,13445571 ! response to calcium ion GO:0051592 81 47 0,000 0,12310884 0,13712957 ! positive regulation of DNA binding GO:0043388 73 47 0,000 0,12310884 0,13706611 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,12310884 0,13700272 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,12310884 0,13693938 ! methylation GO:0032259 90 47 0,000 0,12310884 0,1368761 ! protein homooligomerization GO:0051260 76 47 0,000 0,12310884 0,13681287 ! mitochondrial transport GO:0006839 82 48 0,000 0,12555842 0,13947071 ! Notch signaling pathway GO:0007219 96 48 0,000 0,12555842 0,13940635 ! cellular component disassembly GO:0022411 86 48 0,000 0,12555842 0,13934205 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,12555842 0,13927781 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,12555842 0,13921362 ! activation of caspase activity GO:0006919 84 48 0,000 0,12555842 0,1391495 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,12555842 0,13908543 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,12800124 0,14172618 ! regulation of ion transport GO:0043269 77 49 0,000 0,12800124 0,14166098 ! response to temperature stimulus GO:0009266 76 49 0,000 0,12800124 0,14159585 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,12800124 0,14153078 ! endocrine system development GO:0035270 104 49 0,000 0,12800124 0,14146577 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,12800124 0,14140082 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,12800124 0,14133592 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,12800124 0,14127109 ! detection of abiotic stimulus GO:0009582 74 49 0,000 0,12800124 0,14120632 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,13043731 0,14382776 ! neuromuscular process GO:0050905 99 50 0,000 0,13043731 0,14376188 ! regulation of ossification GO:0030278 117 50 0,000 0,13043731 0,14369605 ! inner ear development GO:0048839 79 50 0,000 0,13043731 0,14363029 ! histone modification GO:0016570 91 50 0,000 0,13043731 0,14356458 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,13043731 0,14349894 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,13043731 0,14343335 ! positive regulation of binding GO:0051099 78 51 0,000 0,13286666 0,146038 ! viral infectious cycle GO:0019058 99 51 0,000 0,13286666 0,14597132 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,13286666 0,1459047 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,13286666 0,14583813 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,13286666 0,14577163 ! excretion GO:0007588 83 51 0,000 0,13286666 0,14570519 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,13286666 0,14563881 ! chromatin remodeling GO:0006338 109 51 0,000 0,13286666 0,14557249 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,13286666 0,14550623 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,13286666 0,14544003 ! vesicle organization GO:0016050 107 51 0,000 0,13286666 0,14537389 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,13286666 0,14530781 ! membrane fusion GO:0006944 110 52 0,000 0,13528931 0,14789008 ! covalent chromatin modification GO:0016569 101 52 0,000 0,13528931 0,14782292 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,13528931 0,14775582 ! amino acid activation GO:0043038 92 52 0,000 0,13528931 0,14768878 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,13770526 0,15025799 ! RNA catabolic process GO:0006401 93 53 0,000 0,13770526 0,15018987 ! regulation of translational initiation GO:0006446 82 53 0,000 0,13770526 0,15012182 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,13770526 0,15005383 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,13770526 0,1499859 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,13770526 0,14991804 ! cell maturation GO:0048469 100 53 0,000 0,13770526 0,14985023 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,13770526 0,14978249 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,13770526 0,1497148 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,14011455 0,1522654 ! cell recognition GO:0008037 85 54 0,000 0,14011455 0,15219666 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,14011455 0,15212798 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,14011455 0,15205936 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,14011455 0,1519908 ! chloride transport GO:0006821 90 55 0,000 0,14251718 0,15452742 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,14251718 0,15445781 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,14251718 0,15438827 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,14251718 0,15431878 ! aging GO:0007568 103 55 0,000 0,14251718 0,15424936 ! gastrulation GO:0007369 112 55 0,000 0,14251718 0,15418001 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,14251718 0,15411071 ! RNA elongation GO:0006354 79 55 0,000 0,14251718 0,15404148 ! nuclear export GO:0051168 97 55 0,000 0,14251718 0,15397231 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,14251718 0,1539032 ! regulation of actin filament length GO:0030832 105 56 0,000 0,14491318 0,15642042 ! sensory perception of smell GO:0007608 80 56 0,000 0,14491318 0,15635028 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,14491318 0,15628019 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,14491318 0,15621018 ! proton transport GO:0015992 94 56 0,000 0,14491318 0,15614022 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,14491318 0,15607033 ! hydrogen transport GO:0006818 97 58 0,000 0,14968535 0,16113779 ! regulation of endocytosis GO:0030100 91 58 0,000 0,14968535 0,16106572 ! adult behavior GO:0030534 99 58 0,000 0,14968535 0,16099372 ! positive regulation of secretion GO:0051047 95 59 0,000 0,15206156 0,16347637 ! regulation of cellular component size GO:0032535 109 59 0,000 0,15206156 0,16340336 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,15206156 0,16333041 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,15206156 0,16325753 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,15206156 0,16318471 ! DNA catabolic process GO:0006308 86 59 0,000 0,15206156 0,16311196 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,15206156 0,16303927 ! establishment of organelle localization GO:0051656 109 59 0,000 0,15206156 0,16296664 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,15443121 0,16543254 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,15443121 0,16535892 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,15443121 0,16528536 ! camera-type eye development GO:0043010 116 60 0,000 0,15443121 0,16521187 ! kidney development GO:0001822 122 60 0,000 0,15443121 0,16513844 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,15679431 0,1675909 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,15679431 0,16751648 ! mesoderm development GO:0007498 119 61 0,000 0,15679431 0,16744213 ! tRNA processing GO:0008033 89 61 0,000 0,15679431 0,16736784 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,15679431 0,16729362 ! ear development GO:0043583 103 62 0,000 0,15915089 0,16973273 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,15915089 0,16965753 ! gonad development GO:0008406 98 62 0,000 0,15915089 0,16958239 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,16150096 0,17201031 ! regulation of lipid metabolic process GO:0019216 115 63 0,000 0,16150096 0,1719342 ! detection of external stimulus GO:0009581 91 63 0,000 0,16150096 0,17185816 ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,16150096 0,17178218 ! steroid hormone receptor signaling pathway GO:0030518 129 63 0,000 0,16150096 0,17170628 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,16384454 0,174121 ! cell redox homeostasis GO:0045454 102 64 0,000 0,16384454 0,17404413 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,16384454 0,17396732 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,16384454 0,17389058 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,16384454 0,17381391 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,16618164 0,17621553 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,16618164 0,1761379 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,16618164 0,17606034 GO:0035113|embryonic appendage morphogenesis, ! germ cell development GO:0007281 118 65 0,000 0,16618164 0,17598285 ! myeloid cell differentiation GO:0030099 111 65 0,000 0,16618164 0,17590542 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,16851229 0,17829401 ! extracellular matrix organization GO:0030198 133 66 0,000 0,16851229 0,17821564 ! secondary metabolic process GO:0019748 116 66 0,000 0,16851229 0,17813734 ! developmental maturation GO:0021700 116 66 0,000 0,16851229 0,1780591 ! cell projection assembly GO:0030031 120 66 0,000 0,16851229 0,17798094 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,17083651 0,18035658 ! negative regulation of cell growth GO:0030308 132 67 0,000 0,17083651 0,18027747 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,17083651 0,18019844 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,17083651 0,18011947 ! hexose catabolic process GO:0019320 104 67 0,000 0,17083651 0,18004058 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,17083651 0,17996175 ! activation of immune response GO:0002253 105 67 0,000 0,17083651 0,17988299 ! amino acid transport GO:0006865 125 68 0,000 0,1731543 0,18224377 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,1731543 0,18216408 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,1731543 0,18208446 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 0,000 0,1731543 0,18200492 ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,1731543 0,18192544 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,1731543 0,18184603 ! negative regulation of cell size GO:0045792 134 69 0,000 0,1754657 0,18419305 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,1754657 0,18411272 ! urogenital system development GO:0001655 137 69 0,000 0,1754657 0,18403246 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,1754657 0,18395227 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,1754657 0,18387215 ! antigen processing and presentation GO:0019882 104 69 0,000 0,1754657 0,1837921 ! appendage morphogenesis GO:0035107 135 70 0,000 0,1777707 0,18612546 GO:0035108|limb morphogenesis, ! amine catabolic process GO:0009310 117 71 0,000 0,18006934 0,18845013 ! reproductive structure development GO:0048608 113 71 0,000 0,18006934 0,18836819 ! appendage development GO:0048736 136 71 0,000 0,18006934 0,18828633 GO:0060173|limb development, ! humoral immune response GO:0006959 109 71 0,000 0,18006934 0,18820454 ! B cell activation GO:0042113 160 71 0,000 0,18006934 0,18812281 ! regulation of immune effector process GO:0002697 137 71 0,000 0,18006934 0,18804116 ! acute inflammatory response GO:0002526 113 72 0,000 0,18236163 0,19035232 ! regulation of caspase activity GO:0043281 122 72 0,000 0,18236163 0,19026977 ! carbohydrate transport GO:0008643 110 72 0,000 0,18236163 0,1901873 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,18236163 0,19010489 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,18236163 0,19002256 ! learning or memory GO:0007611 147 73 0,000 0,18464759 0,19232126 ! regulation of blood pressure GO:0008217 125 73 0,000 0,18464759 0,19223804 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,18464759 0,19215489 ! fertilization GO:0009566 90 73 0,000 0,18464759 0,19207182 ! transition metal ion transport GO:0000041 126 74 0,000 0,18692724 0,19435909 ! neurotransmitter transport GO:0006836 123 74 0,000 0,18692724 0,19427513 ! meiosis GO:0007126 121 74 0,000 0,18692724 0,19419125 GO:0051327|M phase of meiotic cell cycle, ! exocytosis GO:0006887 133 74 0,000 0,18692724 0,19410744 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,18692724 0,1940237 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,18692724 0,19394003 ! regulation of endopeptidase activity GO:0052548 125 74 0,000 0,18692724 0,19385644 ! eye development GO:0001654 143 74 0,000 0,18692724 0,19377291 ! organelle localization GO:0051640 136 74 0,000 0,18692724 0,19368946 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,18920058 0,19596065 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,18920058 0,19587633 ! meiotic cell cycle GO:0051321 122 75 0,000 0,18920058 0,19579209 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,18920058 0,19570791 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,19146765 0,19796784 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,19146765 0,1978828 ! defense response to bacterium GO:0042742 89 76 0,000 0,19146765 0,19779783 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,19146765 0,19771294 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,19146765 0,19762812 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,19372845 0,19987592 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,19372845 0,19979025 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,19372845 0,19970465 ! positive regulation of lymphocyte activation GO:0051251 127 77 0,000 0,19372845 0,19961912 ! blood coagulation GO:0007596 146 78 0,000 0,195983 0,20185578 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,195983 0,20176941 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,195983 0,20168311 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,19823133 0,20390961 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,19823133 0,20382247 ! activation of protein kinase activity GO:0032147 147 79 0,000 0,19823133 0,2037354 ! regulation of peptidase activity GO:0052547 134 79 0,000 0,19823133 0,20364841 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,19823133 0,20356149 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,19823133 0,20347465 ! response to metal ion GO:0010038 140 80 0,000 0,20047344 0,20568831 ! muscle cell differentiation GO:0042692 159 80 0,000 0,20047344 0,20560064 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,20047344 0,20551304 ! protein import into nucleus GO:0006606 158 80 0,000 0,20047344 0,20542551 ! inorganic anion transport GO:0015698 138 80 0,000 0,20047344 0,20533806 ! T cell activation GO:0042110 168 81 0,000 0,20270936 0,20753988 ! digestion GO:0007586 112 81 0,000 0,20270936 0,2074516 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,20270936 0,2073634 ! nuclear import GO:0051170 161 81 0,000 0,20270936 0,20727527 ! regulation of neuron differentiation GO:0045664 167 81 0,000 0,20270936 0,20718722 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,20493909 0,20937726 ! response to drug GO:0042493 143 82 0,000 0,20493909 0,2092884 ! response to nutrient GO:0007584 125 82 0,000 0,20493909 0,2091996 ! hemostasis GO:0007599 158 84 0,000 0,2093801 0,21364229 ! negative regulation of growth GO:0045926 155 84 0,000 0,2093801 0,21355173 ! regulation of ligase activity GO:0051340 142 84 0,000 0,2093801 0,21346124 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,2093801 0,21337083 ! response to unfolded protein GO:0006986 131 85 0,000 0,2115914 0,21553299 ! nucleosome assembly GO:0006334 122 85 0,000 0,2115914 0,21544178 ! one-carbon metabolic process GO:0006730 154 85 0,000 0,2115914 0,21535064 ! positive regulation of cell activation GO:0050867 145 85 0,000 0,2115914 0,21525959 GO:0002696|positive regulation of leukocyte activation, ! amine biosynthetic process GO:0009309 138 86 0,000 0,2137966 0,21741108 ! response to inorganic substance GO:0010035 153 86 0,000 0,2137966 0,21731923 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,2137966 0,21722745 ! chromatin assembly GO:0031497 124 86 0,000 0,2137966 0,21713576 ! tube morphogenesis GO:0035239 176 86 0,000 0,2137966 0,21704414 ! mitochondrion organization GO:0007005 148 86 0,000 0,2137966 0,2169526 ! alcohol catabolic process GO:0046164 130 86 0,000 0,2137966 0,21686113 ! amine transport GO:0015837 155 86 0,000 0,2137966 0,21676975 ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,21599569 0,21890718 ! protein localization in nucleus GO:0034504 176 87 0,000 0,21599569 0,21881501 ! cellular respiration GO:0045333 135 88 0,000 0,21818871 0,22094362 ! regulation of neurological system process GO:0031644 148 88 0,000 0,21818871 0,22085067 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,21818871 0,2207578 ! cellular defense response GO:0006968 114 89 0,000 0,22037567 0,22287678 ! sex differentiation GO:0007548 145 90 0,000 0,22255658 0,22498787 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,22255658 0,22489338 ! sterol metabolic process GO:0016125 152 91 0,000 0,22473147 0,22699576 ! response to protein stimulus GO:0051789 149 91 0,000 0,22473147 0,22690051 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,22473147 0,22680533 ! nucleosome organization GO:0034728 138 92 0,000 0,22690034 0,2288982 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,22690034 0,22880227 ! vitamin metabolic process GO:0006766 139 92 0,000 0,22690034 0,22870642 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,22906322 0,23078982 GO:0010498|proteasomal protein catabolic process, ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,23122011 0,23286546 ! female pregnancy GO:0007565 164 94 0,000 0,23122011 0,23276803 ! transcription initiation GO:0006352 153 94 0,000 0,23122011 0,23267068 ! forebrain development GO:0030900 188 95 0,000 0,23337105 0,23473693 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,23337105 0,23463884 ! leukocyte differentiation GO:0002521 202 96 0,000 0,23551604 0,23669657 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,23551604 0,23659774 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,23551604 0,23649899 ! positive regulation of immune response GO:0050778 156 96 0,000 0,23551604 0,23640033 ! detection of stimulus GO:0051606 151 96 0,000 0,23551604 0,23630174 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,23765509 0,23834854 ! protein ubiquitination GO:0016567 217 97 0,000 0,23765509 0,23824923 ! hormone metabolic process GO:0042445 157 97 0,000 0,23765509 0,23815 ! response to virus GO:0009615 160 98 0,000 0,23978824 0,24018755 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,23978824 0,2400876 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,23978824 0,23998773 GO:0016054|organic acid catabolic process, ! Golgi vesicle transport GO:0048193 207 99 0,000 0,24191548 0,24201607 ! cell cycle arrest GO:0007050 213 100 0,000 0,24403685 0,24403685