pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6435-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! induction of positive chemotaxis GO:0050930 17 9 3,000 7,964E-09 1,946E-05 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 4,000 1,982E-08 2,42E-05 ! regulation of positive chemotaxis GO:0050926 22 12 3,000 3,108E-08 2,531E-05 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of locomotion GO:0040017 44 22 3,000 4,493E-07 2,744E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 45 23 3,000 5,427E-07 2,652E-04 ! regulation of behavior GO:0050795 48 25 3,000 7,718E-07 3,143E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 2,000 7,963E-07 2,779E-04 ! protein amino acid autophosphorylation GO:0046777 157 64 4,000 1,175E-06 3,588E-04 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 2,000 1,271E-06 3,451E-04 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 2,000 2,713E-06 6,628E-04 ! chondrocyte differentiation GO:0002062 27 11 2,000 3,723E-06 8,268E-04 ! negative regulation of glucose import GO:0046325 18 11 2,000 3,723E-06 7,579E-04 GO:0010829|negative regulation of glucose transport, ! positive regulation of response to external stimulus GO:0032103 88 44 3,000 7,943E-06 1,493E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 2,000 8,162E-06 1,424E-03 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 1,018E-05 1,658E-03 ! induction of apoptosis by extracellular signals GO:0008624 99 50 3,000 1,33E-05 2,031E-03 ! neutrophil chemotaxis GO:0030593 29 17 2,000 1,515E-05 2,177E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 1,814E-05 2,463E-03 ! response to UV GO:0009411 120 55 3,000 1,948E-05 2,505E-03 ! positive regulation of cell migration GO:0030335 137 58 3,000 2,407E-05 2,94E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 2,000 2,524E-05 2,937E-03 ! regulation of glucose import GO:0046324 30 20 2,000 2,524E-05 2,803E-03 GO:0010827|regulation of glucose transport, ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 2,939E-05 3,122E-03 ! positive regulation of inflammatory response GO:0050729 41 21 2,000 2,939E-05 2,992E-03 ! inactivation of MAPK activity GO:0000188 45 22 2,000 3,396E-05 3,318E-03 ! positive regulation of intracellular transport GO:0032388 42 22 2,000 3,396E-05 3,191E-03 ! positive regulation of cell motion GO:0051272 157 65 3,000 3,783E-05 3,423E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 4,444E-05 3,878E-03 ! negative regulation of phosphorylation GO:0042326 52 24 2,000 4,444E-05 3,744E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 3,000 4,788E-05 3,899E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 3,000 4,788E-05 3,773E-03 ! negative regulation of kinase activity GO:0033673 145 70 3,000 5,067E-05 3,868E-03 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 2,000 5,686E-05 4,209E-03 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of transferase activity GO:0051348 155 74 3,000 6,303E-05 4,529E-03 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 6,383E-05 4,455E-03 ! negative regulation of protein modification process GO:0031400 66 28 2,000 7,134E-05 4,841E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 8,109E-05 5,354E-03 ! apoptotic cell clearance GO:0043277 23 5 1,000 8,109E-05 5,213E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 8,109E-05 5,079E-03 ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 8,109E-05 4,952E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 8,109E-05 4,832E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 8,109E-05 4,717E-03 ! positive regulation of phosphorylation GO:0042327 149 81 3,000 8,974E-05 5,099E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 3,000 9,869E-05 5,479E-03 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of transport GO:0051051 164 85 3,000 1,083E-04 5,877E-03 ! cellular response to hormone stimulus GO:0032870 182 85 3,000 1,083E-04 5,75E-03 ! leukocyte chemotaxis GO:0030595 55 33 2,000 1,176E-04 6,112E-03 GO:0060326|cell chemotaxis, ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 1,000 1,214E-04 6,179E-03 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! early endosome to late endosome transport GO:0045022 16 6 1,000 1,214E-04 6,053E-03 ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 1,287E-04 6,288E-03 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 1,534E-04 7,348E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,696E-04 7,97E-03 ! mRNA stabilization GO:0048255 18 7 1,000 1,696E-04 7,82E-03 GO:0043489|RNA stabilization, ! male sex determination GO:0030238 15 7 1,000 1,696E-04 7,675E-03 ! spindle checkpoint GO:0031577 16 7 1,000 1,696E-04 7,535E-03 ! negative regulation of nuclear division GO:0051784 15 7 1,000 1,696E-04 7,401E-03 GO:0045839|negative regulation of mitosis, ! cellular response to insulin stimulus GO:0032869 85 38 2,000 1,799E-04 7,711E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 2,258E-04 9,51E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 2,258E-04 9,348E-03 ! ER overload response GO:0006983 13 8 1,000 2,258E-04 9,193E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 2,258E-04 9,042E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 2,258E-04 8,896E-03 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 1,000 2,258E-04 8,755E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 2,258E-04 8,618E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 2,258E-04 8,486E-03 ! regulation of intracellular protein transport GO:0033157 86 42 2,000 2,428E-04 8,987E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 2,897E-04 0,01056449 ! regulation of glycolysis GO:0006110 20 9 1,000 2,897E-04 0,01040913 ! microtubule bundle formation GO:0001578 22 9 1,000 2,897E-04 0,01025827 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 2,897E-04 0,01011172 ! receptor clustering GO:0043113 20 9 1,000 2,897E-04 9,969E-03 ! postreplication repair GO:0006301 25 9 1,000 2,897E-04 9,831E-03 ! regulation of epithelial cell proliferation GO:0050678 122 45 2,000 2,983E-04 9,981E-03 ! induction of apoptosis by intracellular signals GO:0008629 95 45 2,000 2,983E-04 9,846E-03 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 2,000 3,184E-04 0,01037136 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 2,000 3,184E-04 0,01023489 ! leukocyte migration GO:0050900 75 46 2,000 3,184E-04 0,01010197 ! positive regulation of protein transport GO:0051222 80 46 2,000 3,184E-04 9,972E-03 ! regulation of JNK cascade GO:0046328 104 47 2,000 3,394E-04 0,0104957 ! response to insulin stimulus GO:0032868 98 47 2,000 3,394E-04 0,0103645 ! positive regulation of defense response GO:0031349 88 48 2,000 3,613E-04 0,01089629 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 2,000 3,613E-04 0,01076341 ! regulation of inflammatory response GO:0050727 84 48 2,000 3,613E-04 0,01063373 ! regulation of developmental growth GO:0048638 16 10 1,000 3,615E-04 0,01051332 ! lung alveolus development GO:0048286 26 10 1,000 3,615E-04 0,01038963 ! motor axon guidance GO:0008045 22 10 1,000 3,615E-04 0,01026882 ! regulation of bone resorption GO:0045124 25 10 1,000 3,615E-04 0,01015079 ! protein heterooligomerization GO:0051291 17 10 1,000 3,615E-04 0,01003544 ! induction of an organ GO:0001759 17 10 1,000 3,615E-04 9,923E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 3,615E-04 9,812E-03 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 3,615E-04 9,705E-03 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 1,000 4,41E-04 0,01171028 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 4,41E-04 0,01158437 ! blood vessel remodeling GO:0001974 30 11 1,000 4,41E-04 0,01146113 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 4,41E-04 0,01134048 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 4,41E-04 0,01122235 ! regulation of embryonic development GO:0045995 35 11 1,000 4,41E-04 0,01110666 ! cartilage development GO:0051216 99 53 2,000 4,843E-04 0,01207186 ! regulation of muscle contraction GO:0006937 94 54 2,000 5,117E-04 0,01262658 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 5,282E-04 0,01290395 ! virus-host interaction GO:0019048 30 12 1,000 5,282E-04 0,01277619 ! dopamine receptor signaling pathway GO:0007212 28 12 1,000 5,282E-04 0,01265093 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 1,000 5,282E-04 0,01252811 ! regulation of leukocyte migration GO:0002685 29 12 1,000 5,282E-04 0,01240764 ! negative regulation of mast cell proliferation GO:0070667 24 12 1,000 5,282E-04 0,01228948 GO:0042130|negative regulation of T cell proliferation, ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 5,282E-04 0,01217354 ! developmental induction GO:0031128 22 12 1,000 5,282E-04 0,01205977 GO:0045168|cell-cell signaling involved in cell fate specification, ! localization within membrane GO:0051668 26 12 1,000 5,282E-04 0,0119481 ! regulation of intracellular transport GO:0032386 108 57 2,000 5,998E-04 0,01344433 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 6,231E-04 0,0138378 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 35 13 1,000 6,231E-04 0,01371313 ! regulation of mRNA stability GO:0043488 32 13 1,000 6,231E-04 0,0135907 ! cytoplasmic sequestering of protein GO:0051220 25 13 1,000 6,231E-04 0,01347042 ! regulation of RNA stability GO:0043487 33 14 1,000 7,256E-04 0,01554849 ! regulation of heart contraction GO:0008016 123 61 2,000 7,317E-04 0,01554413 ! negative regulation of response to stimulus GO:0048585 106 61 2,000 7,317E-04 0,01541013 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 8,356E-04 0,01744785 ! actin cytoskeleton reorganization GO:0031532 38 15 1,000 8,356E-04 0,01729998 ! response to peptide hormone stimulus GO:0043434 129 64 2,000 8,418E-04 0,01728188 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 9,532E-04 0,01940552 ! positive regulation of cell size GO:0045793 29 16 1,000 9,532E-04 0,01924514 ! positive regulation of protein import into nucleus GO:0042307 34 16 1,000 9,532E-04 0,0190874 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 9,532E-04 0,01893221 ! negative regulation of leukocyte proliferation GO:0070664 32 16 1,000 9,532E-04 0,01877953 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of cellular response to stress GO:0080135 142 68 2,000 1,004E-03 0,01962626 ! lung development GO:0030324 165 69 2,000 1,048E-03 0,02031332 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 1,078E-03 0,02074185 ! signal complex assembly GO:0007172 47 17 1,000 1,078E-03 0,02057981 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 1,078E-03 0,02042027 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 1,078E-03 0,02026319 GO:0031114|regulation of microtubule depolymerization, ! negative regulation of homeostatic process GO:0032845 36 17 1,000 1,078E-03 0,02010851 ! regulation of MAPKKK cascade GO:0043408 157 72 2,000 1,185E-03 0,02193465 ! respiratory tube development GO:0030323 171 72 2,000 1,185E-03 0,02176973 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 1,211E-03 0,02207426 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 1,211E-03 0,02191075 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 1,211E-03 0,02174964 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 2,000 1,283E-03 0,02287605 ! respiratory system development GO:0060541 175 74 2,000 1,283E-03 0,02271028 ! positive regulation of translation GO:0045727 31 19 1,000 1,351E-03 0,02373932 ! mitotic chromosome condensation GO:0007076 37 19 1,000 1,351E-03 0,02356976 ! neuromuscular junction development GO:0007528 43 19 1,000 1,351E-03 0,02340259 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 1,351E-03 0,02323779 ! regulation of catabolic process GO:0009894 173 77 2,000 1,439E-03 0,02457779 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 1,000 1,498E-03 0,02541357 ! phosphoinositide phosphorylation GO:0046854 40 20 1,000 1,498E-03 0,02523831 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 1,498E-03 0,02506544 GO:0010675|regulation of cellular carbohydrate metabolic process, ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 1,498E-03 0,02489493 ! negative regulation of T cell activation GO:0050868 41 20 1,000 1,498E-03 0,02472672 ! negative regulation of organelle organization GO:0010639 181 80 2,000 1,606E-03 0,02632925 ! lipid phosphorylation GO:0046834 43 21 1,000 1,653E-03 0,02691475 ! peptidyl-serine modification GO:0018209 50 22 1,000 1,814E-03 0,02935522 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 1,814E-03 0,0291621 ! protein stabilization GO:0050821 41 22 1,000 1,814E-03 0,02897149 ! positive regulation of DNA replication GO:0045740 44 23 1,000 1,984E-03 0,03146576 ! gluconeogenesis GO:0006094 38 23 1,000 1,984E-03 0,03126276 ! activation of pro-apoptotic gene products GO:0008633 51 23 1,000 1,984E-03 0,03106236 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 1,000 1,984E-03 0,03086451 ! regulation of protein transport GO:0051223 165 87 2,000 2,042E-03 0,03157156 GO:0070201|regulation of establishment of protein localization, ! positive regulation of cell adhesion GO:0045785 61 24 1,000 2,16E-03 0,03318476 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 2,16E-03 0,03297736 ! sex determination GO:0007530 48 24 1,000 2,16E-03 0,03277253 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 2,16E-03 0,03257023 ! negative regulation of catabolic process GO:0009895 52 24 1,000 2,16E-03 0,03237041 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 2,16E-03 0,03217303 ! positive regulation of protein modification process GO:0031401 156 90 2,000 2,249E-03 0,03330051 ! positive regulation of fibroblast proliferation GO:0048146 48 25 1,000 2,343E-03 0,03448486 ! vasculogenesis GO:0001570 49 25 1,000 2,343E-03 0,03427836 ! receptor metabolic process GO:0043112 53 25 1,000 2,343E-03 0,03407432 ! chromosome condensation GO:0030261 48 25 1,000 2,343E-03 0,0338727 ! interaction with host GO:0051701 66 25 1,000 2,343E-03 0,03367345 ! protein tetramerization GO:0051262 57 25 1,000 2,343E-03 0,03347653 ! myelination GO:0042552 50 26 1,000 2,534E-03 0,03598809 ! pyruvate metabolic process GO:0006090 43 26 1,000 2,534E-03 0,03578007 ! regulation of transcription factor import into nucleus GO:0042990 58 26 1,000 2,534E-03 0,03557444 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 2,534E-03 0,03537115 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 2,534E-03 0,03517018 ! regulation of defense response GO:0031347 171 95 2,000 2,623E-03 0,03619832 ! regulation of endothelial cell proliferation GO:0001936 60 27 1,000 2,731E-03 0,03748693 ! negative regulation of lymphocyte activation GO:0051250 55 27 1,000 2,731E-03 0,0372775 ! regulation of protein localization GO:0032880 188 97 2,000 2,782E-03 0,0377594 ! interphase of mitotic cell cycle GO:0051329 224 98 2,000 2,864E-03 0,0386566 ! regulation of fibroblast proliferation GO:0048145 56 28 1,000 2,936E-03 0,03940961 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 1,000 2,936E-03 0,03919426 ! circadian rhythm GO:0007623 56 28 1,000 2,936E-03 0,03898125 ! dendrite development GO:0016358 67 28 1,000 2,936E-03 0,03877054 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 2,936E-03 0,03856209 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 3,148E-03 0,04112022 ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 3,148E-03 0,04090149 ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 3,366E-03 0,04350987 GO:0043433|negative regulation of transcription factor activity, ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 3,592E-03 0,0461795 ! ensheathment of neurons GO:0007272 64 31 1,000 3,592E-03 0,04593772 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 60 31 1,000 3,592E-03 0,04569846 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 3,824E-03 0,04840207 ! hexose biosynthetic process GO:0019319 53 32 1,000 3,824E-03 0,04815258 ! peripheral nervous system development GO:0007422 68 32 1,000 3,824E-03 0,04790564 ! positive regulation of catabolic process GO:0009896 72 32 1,000 3,824E-03 0,04766122 ! negative regulation of protein transport GO:0051224 74 33 1,000 4,063E-03 0,05038453 ! cell fate specification GO:0001708 56 34 1,000 4,309E-03 0,05316395 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 4,309E-03 0,05289679 ! calcium-mediated signaling GO:0019722 67 35 1,000 4,561E-03 0,05571816 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 4,821E-03 0,05859286 ! negative regulation of DNA binding GO:0043392 67 36 1,000 4,821E-03 0,0583028 ! monosaccharide biosynthetic process GO:0046364 57 36 1,000 4,821E-03 0,05801559 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 1,000 5,087E-03 0,06091649 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 5,087E-03 0,06061934 ! sister chromatid segregation GO:0000819 65 37 1,000 5,087E-03 0,06032507 ! tissue remodeling GO:0048771 78 37 1,000 5,087E-03 0,06003365 ! maintenance of protein location in cell GO:0032507 89 37 1,000 5,087E-03 0,05974502 ! regulation of microtubule-based process GO:0032886 86 37 1,000 5,087E-03 0,05945916 ! negative regulation of cell activation GO:0050866 69 37 1,000 5,087E-03 0,05917602 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 5,359E-03 0,06205181 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 1,000 5,359E-03 0,06175912 ! regulation of protein stability GO:0031647 77 38 1,000 5,359E-03 0,06146917 ! glycogen metabolic process GO:0005977 63 38 1,000 5,359E-03 0,06118193 ! negative regulation of binding GO:0051100 71 39 1,000 5,639E-03 0,06406965 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 5,639E-03 0,06377303 ! carbohydrate homeostasis GO:0033500 59 39 1,000 5,639E-03 0,06347914 GO:0042593|glucose homeostasis, ! glucan metabolic process GO:0044042 64 39 1,000 5,639E-03 0,06318795 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 1,000 5,924E-03 0,06608672 ! regulation of action potential in neuron GO:0019228 80 40 1,000 5,924E-03 0,06578633 ! maintenance of protein location GO:0045185 95 41 1,000 6,216E-03 0,06871897 ! alcohol biosynthetic process GO:0046165 65 42 1,000 6,515E-03 0,07169629 ! regulation of T cell differentiation GO:0045580 78 42 1,000 6,515E-03 0,07137479 ! hormone-mediated signaling GO:0009755 84 43 1,000 6,82E-03 0,07438373 ! regulation of T cell proliferation GO:0042129 80 43 1,000 6,82E-03 0,07405313 ! energy reserve metabolic process GO:0006112 76 44 1,000 7,132E-03 0,07709261 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 7,132E-03 0,076753 ! phagocytosis GO:0006909 105 44 1,000 7,132E-03 0,07641636 ! maintenance of location in cell GO:0051651 101 45 1,000 7,45E-03 0,0794734 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 7,774E-03 0,08257086 ! cell growth GO:0016049 90 46 1,000 7,774E-03 0,08221341 ! positive regulation of cell cycle GO:0045787 96 48 1,000 8,441E-03 0,08888334 ! endosome transport GO:0016197 127 48 1,000 8,441E-03 0,08850186 ! vascular process in circulatory system GO:0003018 85 48 1,000 8,441E-03 0,08812365 ! regulation of lymphocyte differentiation GO:0045619 92 49 1,000 8,784E-03 0,09131275 ! JNK cascade GO:0007254 106 49 1,000 8,784E-03 0,09092584 ! regulation of mast cell proliferation GO:0070666 89 49 1,000 8,784E-03 0,09054218 ! regulation of action potential GO:0001508 102 50 1,000 9,133E-03 0,09374412 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 9,488E-03 0,09698181 ! peptide metabolic process GO:0006518 80 51 1,000 9,488E-03 0,09657772 ! negative regulation of immune system process GO:0002683 101 51 1,000 9,488E-03 0,09617698 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 9,849E-03 0,09942588 ! positive regulation of growth GO:0045927 96 53 1,000 0,01021623 0,10270881 ! regulation of leukocyte proliferation GO:0070663 97 53 1,000 0,01021623 0,10228787 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! synapse organization GO:0050808 102 53 1,000 0,01021623 0,10187037 ! regulation of angiogenesis GO:0045765 125 54 1,000 0,01058948 0,10516299 ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,01058948 0,10473722 GO:0010863|positive regulation of phospholipase C activity, ! regulation of cell shape GO:0008360 142 54 1,000 0,01058948 0,1043149 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,0109687 0,10761661 ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,01135386 0,1109499 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,01135386 0,11050787 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,01135386 0,11006934 ! regulation of DNA replication GO:0006275 105 56 1,000 0,01135386 0,10963429 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 1,000 0,01174491 0,11296386 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,01174491 0,11252087 ! muscle fiber development GO:0048747 131 57 1,000 0,01174491 0,11208133 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,01174491 0,11164522 ! heart morphogenesis GO:0003007 105 57 1,000 0,01174491 0,11121249 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,01214183 0,11452698 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,01214183 0,11408649 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,01214183 0,11364938 ! maintenance of location GO:0051235 124 58 1,000 0,01214183 0,1132156 ! lipid modification GO:0030258 112 60 1,000 0,0129531 0,12032101 ! viral reproductive process GO:0022415 132 62 1,000 0,01378739 0,12758556 ! regulation of homeostatic process GO:0032844 148 62 1,000 0,01378739 0,12710411 ! regulation of mitosis GO:0007088 112 63 1,000 0,01421307 0,13053585 GO:0051783|regulation of nuclear division, ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,0142671 0,13054126 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,0142671 0,13005417 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,0142671 0,1295707 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,0142671 0,1290908 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,0142671 0,12861445 ! neuron fate determination GO:0048664 7 5 0,000 0,0142671 0,12814161 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,0142671 0,12767222 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,0142671 0,12720627 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,0142671 0,1267437 ! polyol transport GO:0015791 12 5 0,000 0,0142671 0,12628448 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,0142671 0,12582858 ! response to superoxide GO:0000303 10 5 0,000 0,0142671 0,12537596 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,0142671 0,12492658 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,0142671 0,12448042 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,0142671 0,12403743 ! female meiosis GO:0007143 10 5 0,000 0,0142671 0,12359758 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,0142671 0,12316084 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,0142671 0,12272717 ! hypothalamus development GO:0021854 9 5 0,000 0,0142671 0,12229655 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,0142671 0,12186894 ! cobalt ion transport GO:0006824 11 5 0,000 0,0142671 0,12144431 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,0142671 0,12102263 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,0142671 0,12060387 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,0142671 0,12018799 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,0142671 0,11977497 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,0142671 0,11936478 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,0142671 0,1189574 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,0142671 0,11855278 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,0142671 0,11815091 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,0142671 0,11775175 ! transposition GO:0032196 9 5 0,000 0,0142671 0,11735528 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,0142671 0,11696147 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 0,000 0,0142671 0,11657029 ! negative chemotaxis GO:0050919 16 5 0,000 0,0142671 0,11618172 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,0142671 0,11579574 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,0142671 0,11541231 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,0142671 0,11503141 ! behavioral response to pain GO:0048266 10 5 0,000 0,0142671 0,11465302 ! clathrin coat assembly GO:0048268 15 5 0,000 0,0142671 0,11427711 ! Notch receptor processing GO:0007220 11 5 0,000 0,0142671 0,11390365 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,0142671 0,11353263 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 0,000 0,0142671 0,11316402 ! micturition GO:0060073 9 5 0,000 0,0142671 0,11279779 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,0142671 0,11243393 ! copulation GO:0007620 9 5 0,000 0,0142671 0,1120724 ! glial cell fate commitment GO:0021781 14 5 0,000 0,0142671 0,1117132 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,0142671 0,11135628 ! bioluminescence GO:0008218 9 5 0,000 0,0142671 0,11100165 ! spermidine metabolic process GO:0008216 7 5 0,000 0,0142671 0,11064926 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,0142671 0,1102991 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,0142671 0,10995116 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,0142671 0,1096054 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,0142671 0,10926181 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,0142671 0,10892037 ! grooming behavior GO:0007625 6 5 0,000 0,0142671 0,10858105 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,0142671 0,10824384 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,0142671 0,10790872 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,0142671 0,10757567 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,0142671 0,10724467 ! response to protozoan GO:0001562 13 5 0,000 0,0142671 0,1069157 ! lymph vessel development GO:0001945 10 5 0,000 0,0142671 0,10658874 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,0142671 0,10626377 ! endochondral ossification GO:0001958 17 5 0,000 0,0142671 0,10594078 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,0142671 0,10561975 ! single strand break repair GO:0000012 8 5 0,000 0,0142671 0,10530066 ! parathyroid gland development GO:0060017 14 5 0,000 0,0142671 0,10498349 ! anagen GO:0042640 7 5 0,000 0,0142671 0,10466822 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,0142671 0,10435484 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,0142671 0,10404333 ! cytokine secretion GO:0050663 15 5 0,000 0,0142671 0,10373368 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,0142671 0,10342587 ! ceramide catabolic process GO:0046514 7 5 0,000 0,0142671 0,10311987 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,0142671 0,10281568 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,0142671 0,10251329 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,0142671 0,10221266 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,0142671 0,10191379 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,0142671 0,10161667 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,0142671 0,10132127 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,0142671 0,10102759 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,0142671 0,1007356 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,0142671 0,10044529 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,0142671 0,10015666 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,0142671 0,09986968 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,0142671 0,09958433 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,0142671 0,09930062 ! microvillus organization GO:0032528 8 5 0,000 0,0142671 0,09901851 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 12 5 0,000 0,0142671 0,09873801 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,0142671 0,09845909 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,0142671 0,09818174 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,0142671 0,09790595 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,0142671 0,0976317 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,0142671 0,09735899 ! polyol catabolic process GO:0046174 9 5 0,000 0,0142671 0,09708779 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,0142671 0,0968181 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,0142671 0,09654991 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,0142671 0,0962832 ! muscle cell migration GO:0014812 8 5 0,000 0,0142671 0,09601795 ! mitochondrial fission GO:0000266 8 5 0,000 0,0142671 0,09575417 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,0142671 0,09549183 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,0142671 0,09523092 ! mRNA transcription GO:0009299 10 5 0,000 0,0142671 0,09497144 ! nerve growth factor processing GO:0032455 9 5 0,000 0,0142671 0,09471336 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,0142671 0,09445669 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,0142671 0,0942014 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,0142671 0,09394749 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,0142671 0,09369494 ! monocyte activation GO:0042117 10 5 0,000 0,0142671 0,09344375 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,0142671 0,0931939 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,0142671 0,09294538 ! response to food GO:0032094 6 5 0,000 0,0142671 0,09269818 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,0142671 0,0924523 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,0142671 0,09220772 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,0142671 0,09196442 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,0142671 0,09172241 ! forebrain neuron development GO:0021884 13 5 0,000 0,0142671 0,09148167 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,0142671 0,09124219 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,0142671 0,09100396 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,0142671 0,09076697 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,0142671 0,09053121 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,0142671 0,09029668 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,0142671 0,09006335 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,0142671 0,08983123 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,0142671 0,0896003 ! lipid glycosylation GO:0030259 7 5 0,000 0,0142671 0,08937056 ! nucleobase transport GO:0015851 6 5 0,000 0,0142671 0,08914199 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,0142671 0,08891458 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,0142671 0,08868834 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,0142671 0,08846324 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,0142671 0,08823928 ! basic amino acid transport GO:0015802 12 5 0,000 0,0142671 0,08801646 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,0142671 0,08779475 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,0142671 0,08757416 ! actin nucleation GO:0045010 11 5 0,000 0,0142671 0,08735468 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,0142671 0,08713629 ! depurination GO:0045007 5 5 0,000 0,0142671 0,086919 ! depyrimidination GO:0045008 10 5 0,000 0,0142671 0,08670278 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,0142671 0,08648764 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,0142671 0,08627356 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,0142671 0,08606054 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,0142671 0,08584856 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,0142671 0,08563763 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 10 5 0,000 0,0142671 0,08542774 ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,0142671 0,08521887 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,0142671 0,08501102 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,0142671 0,08480418 ! activated T cell proliferation GO:0050798 16 5 0,000 0,0142671 0,08459834 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,0142671 0,0843935 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,0142671 0,08418965 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,0142671 0,08398679 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,0142671 0,0837849 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,0142671 0,08358397 ! response to arsenic GO:0046685 11 5 0,000 0,0142671 0,08338401 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,0142671 0,083185 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,0142671 0,08298695 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,0142671 0,08278983 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,0142671 0,08259364 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,0142671 0,08239839 ! response to mercury ion GO:0046689 8 5 0,000 0,0142671 0,08220405 ! response to cadmium ion GO:0046686 7 5 0,000 0,0142671 0,08201063 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,0142671 0,08181812 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,0142671 0,0816265 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,0142671 0,08143579 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,0142671 0,08124596 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,0142671 0,08105702 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,0142671 0,08086895 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,0142671 0,08068175 ! decidualization GO:0046697 11 5 0,000 0,0142671 0,08049542 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,0142671 0,08030995 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,0142671 0,08012533 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,0142671 0,07994155 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,0142671 0,07975862 ! embryonic cleavage GO:0040016 6 5 0,000 0,0142671 0,07957652 ! peroxisome fission GO:0016559 5 5 0,000 0,0142671 0,07939526 ! histone demethylation GO:0016577 13 5 0,000 0,0142671 0,07921481 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,0142671 0,07903519 ! mitotic recombination GO:0006312 9 5 0,000 0,0142671 0,07885637 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,0142671 0,07867837 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,0142671 0,07850116 ! metaphase plate congression GO:0051310 7 5 0,000 0,0142671 0,07832476 ! regulation of sterol transport GO:0032371 7 5 0,000 0,0142671 0,07814914 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,0142671 0,07797431 ! enteric nervous system development GO:0048484 8 5 0,000 0,0142671 0,07780026 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,0142671 0,07762699 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,0142671 0,07745448 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,0142671 0,07728274 ! muscle cell proliferation GO:0033002 12 5 0,000 0,0142671 0,07711176 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,0142671 0,07694154 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,0142671 0,07677206 ! B cell homeostasis GO:0001782 13 5 0,000 0,0142671 0,07660333 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,0142671 0,07643534 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,0142671 0,07626809 ! metaphase GO:0051323 11 5 0,000 0,0142671 0,07610157 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,0142671 0,07593577 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,0142671 0,07577069 ! cellular response to nutrient GO:0031670 8 5 0,000 0,0142671 0,07560633 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,0142671 0,07544268 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,0142671 0,07527973 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,0142671 0,07511749 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,0142671 0,07495595 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,0142671 0,0747951 ! response to redox state GO:0051775 6 5 0,000 0,0142671 0,07463494 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,0142671 0,07447546 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,0142671 0,07431667 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,0142671 0,07415855 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,0142671 0,0740011 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,0142671 0,07384432 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,0142671 0,0736882 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,0142671 0,07353274 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,0142671 0,07337793 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,0142671 0,07322378 ! striatum development GO:0021756 14 5 0,000 0,0142671 0,07307027 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,0142671 0,0729174 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,0142671 0,07276517 ! glial cell migration GO:0008347 10 5 0,000 0,0142671 0,07261358 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,0142671 0,07246261 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,0142671 0,07231228 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,0142671 0,07216256 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,0142671 0,07201347 ! T cell activation during immune response GO:0002286 9 5 0,000 0,0142671 0,07186498 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,0142671 0,07171711 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,0142671 0,07156985 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,0142671 0,07142319 ! neuroprotection GO:0043526 8 5 0,000 0,0142671 0,07127713 ! regulation of sensory perception GO:0051931 8 5 0,000 0,0142671 0,07113167 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,0142671 0,0709868 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,0142671 0,07084251 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,0142671 0,07069882 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,0142671 0,0705557 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,0142671 0,07041317 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,0142671 0,0702712 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,0142671 0,07012981 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,0142671 0,06998899 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,0142671 0,06984873 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,0142671 0,06970903 ! spindle assembly GO:0051225 6 5 0,000 0,0142671 0,06956989 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,0142671 0,06943131 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,0142671 0,06929327 ! protein palmitoylation GO:0018345 12 5 0,000 0,0142671 0,06915579 ! drug metabolic process GO:0017144 7 5 0,000 0,0142671 0,06901885 ! stem cell division GO:0017145 11 5 0,000 0,0142671 0,06888244 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,0142671 0,06874658 ! organ regeneration GO:0031100 7 5 0,000 0,0142671 0,06861125 ! carnitine metabolic process GO:0009437 8 5 0,000 0,0142671 0,06847646 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,0142671 0,06834219 ! activation of MAPK activity GO:0000187 124 67 1,000 0,01597192 0,07635893 ! chromosome segregation GO:0007059 127 67 1,000 0,01597192 0,07620979 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 1,000 0,01642549 0,0782212 ! viral reproduction GO:0016032 142 68 1,000 0,01642549 0,07806902 ! regulation of lipase activity GO:0060191 137 68 1,000 0,01642549 0,07791743 ! adaptive immune response GO:0002250 126 68 1,000 0,01642549 0,07776643 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,01709624 0,0807855 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,01709624 0,08062954 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,01709624 0,08047419 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,01709624 0,08031943 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,01709624 0,08016526 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,01709624 0,08001169 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,01709624 0,0798587 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,01709624 0,0797063 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,01709624 0,07955448 ! response to oxygen radical GO:0000305 11 6 0,000 0,01709624 0,07940324 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,01709624 0,07925257 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,01709624 0,07910247 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,01709624 0,07895294 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,01709624 0,07880397 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,01709624 0,07865556 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,01709624 0,07850771 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,01709624 0,07836042 ! forebrain regionalization GO:0021871 9 6 0,000 0,01709624 0,07821368 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,01709624 0,07806748 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,01709624 0,07792183 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,01709624 0,07777673 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,01709624 0,07763216 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,01709624 0,07748813 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,01709624 0,07734463 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,01709624 0,07720167 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,01709624 0,07705923 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,01709624 0,07691732 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,01709624 0,07677592 ! malate metabolic process GO:0006108 13 6 0,000 0,01709624 0,07663505 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,01709624 0,07649469 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,01709624 0,07635485 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,01709624 0,07621552 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,01709624 0,07607669 ! protein refolding GO:0042026 15 6 0,000 0,01709624 0,07593837 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,01709624 0,07580055 ! opsonization GO:0008228 8 6 0,000 0,01709624 0,07566323 ! mating behavior GO:0007617 7 6 0,000 0,01709624 0,07552641 ! erythrocyte maturation GO:0043249 8 6 0,000 0,01709624 0,07539008 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,01709624 0,07525424 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,01709624 0,07511889 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,01709624 0,07498403 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,01709624 0,07484965 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,01709624 0,07471575 ! response to interferon-gamma GO:0034341 16 6 0,000 0,01709624 0,07458233 ! toxin metabolic process GO:0009404 11 6 0,000 0,01709624 0,07444938 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,01709624 0,07431691 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,01709624 0,07418491 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,01709624 0,07405337 ! nuclear migration GO:0007097 13 6 0,000 0,01709624 0,07392231 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,01709624 0,0737917 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,01709624 0,07366156 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,01709624 0,07353187 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,01709624 0,07340264 ! thymic T cell selection GO:0045061 16 6 0,000 0,01709624 0,07327386 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,01709624 0,07314554 ! protein lipoylation GO:0009249 10 6 0,000 0,01709624 0,07301766 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,01709624 0,07289023 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,01709624 0,07276325 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,01709624 0,0726367 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,01709624 0,07251059 ! glutamate catabolic process GO:0006538 12 6 0,000 0,01709624 0,07238493 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,01709624 0,07225969 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,01709624 0,07213489 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,01709624 0,07201052 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,01709624 0,07188658 ! hyperosmotic response GO:0006972 10 6 0,000 0,01709624 0,07176306 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,01709624 0,07163997 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,01709624 0,0715173 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,01709624 0,07139505 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,01709624 0,07127321 ! urea metabolic process GO:0019627 7 6 0,000 0,01709624 0,07115179 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,01709624 0,07103079 ! neutrophil activation GO:0042119 7 6 0,000 0,01709624 0,07091019 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,01709624 0,07079 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,01709624 0,07067022 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,01709624 0,07055085 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,01709624 0,07043188 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,01709624 0,0703133 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,01709624 0,07019513 ! neuron apoptosis GO:0051402 15 6 0,000 0,01709624 0,07007735 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,01709624 0,06995997 ! T cell mediated immunity GO:0002456 17 6 0,000 0,01709624 0,06984298 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,01709624 0,06972638 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,01709624 0,06961017 ! carnitine transport GO:0015879 10 6 0,000 0,01709624 0,06949435 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,01709624 0,06937891 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,01709624 0,06926385 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,01709624 0,06914918 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,01709624 0,06903488 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,01709624 0,06892096 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,01709624 0,06880742 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,01709624 0,06869425 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,01709624 0,06858145 ! establishment of spindle localization GO:0051293 16 6 0,000 0,01709624 0,06846902 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,01709624 0,06835696 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,01709624 0,06824527 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,01709624 0,06813394 ! response to UV-C GO:0010225 14 6 0,000 0,01709624 0,06802297 ! astrocyte development GO:0014002 16 6 0,000 0,01709624 0,06791236 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,01709624 0,06780211 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,01709624 0,06769222 ! interaction with symbiont GO:0051702 14 6 0,000 0,01709624 0,06758269 ! regulation of dendrite development GO:0050773 16 6 0,000 0,01709624 0,06747351 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,01709624 0,06736468 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,01709624 0,0672562 ! response to copper ion GO:0046688 10 6 0,000 0,01709624 0,06714807 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,01709624 0,06704029 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,01709624 0,06693286 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,01709624 0,06682576 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,01709624 0,06671901 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,01709624 0,0666126 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,01709624 0,06650653 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,01709624 0,0664008 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,01709624 0,0662954 ! hair follicle maturation GO:0048820 8 6 0,000 0,01709624 0,06619034 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,01709624 0,06608561 ! Schwann cell development GO:0014044 15 6 0,000 0,01709624 0,0659812 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,01709624 0,06587713 ! response to pheromone GO:0019236 6 6 0,000 0,01709624 0,06577339 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,01709624 0,06566997 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,01709624 0,06556688 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,01709624 0,06546411 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,01709624 0,06536166 ! subpallium development GO:0021544 15 6 0,000 0,01709624 0,06525954 ! neural tube patterning GO:0021532 8 6 0,000 0,01709624 0,06515773 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,01709624 0,06505623 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,01709624 0,06495506 ! maintenance of organ identity GO:0048496 9 6 0,000 0,01709624 0,0648542 ! G2 phase GO:0051319 16 6 0,000 0,01709624 0,06475365 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,01709624 0,06465341 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,01709624 0,06455348 ! oxygen homeostasis GO:0032364 10 6 0,000 0,01709624 0,06445386 ! establishment of planar polarity GO:0001736 7 6 0,000 0,01709624 0,06435455 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,01709624 0,06425554 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,01709624 0,06415684 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,01709624 0,06405844 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,01709624 0,06396034 ! receptor internalization GO:0031623 11 6 0,000 0,01709624 0,06386254 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,01709624 0,06376504 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,01709624 0,06366784 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,01709624 0,06357093 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,01709624 0,06347432 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,01709624 0,063378 ! protein deubiquitination GO:0016579 16 6 0,000 0,01709624 0,06328197 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,01709624 0,06318624 ! protein destabilization GO:0031648 9 6 0,000 0,01709624 0,06309079 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,01709624 0,06299563 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,01709624 0,06290076 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,01709624 0,06280617 ! regulation of viral transcription GO:0046782 11 6 0,000 0,01709624 0,06271187 ! progesterone metabolic process GO:0042448 12 6 0,000 0,01709624 0,06261785 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,01709624 0,06252411 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,01709624 0,06243065 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,01709624 0,06233747 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,01709624 0,06224456 ! determination of adult lifespan GO:0008340 17 6 0,000 0,01709624 0,06215194 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,01709624 0,06205959 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,01709624 0,06196751 ! neural plate development GO:0001840 9 6 0,000 0,01709624 0,06187571 ! catecholamine transport GO:0051937 9 6 0,000 0,01709624 0,06178418 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,01709624 0,06169291 ! sensory cilium assembly GO:0035058 10 6 0,000 0,01709624 0,06160192 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,01709624 0,0615112 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,01709624 0,06142074 ! maternal placenta development GO:0001893 12 6 0,000 0,01709624 0,06133055 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,01709624 0,06124062 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,01709624 0,06115096 ! negative regulation of B cell activation GO:0050869 14 6 0,000 0,01709624 0,06106155 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,01709624 0,06097241 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,01709624 0,06088353 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,01709624 0,06079491 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,01709624 0,06070654 GO:0055081|anion homeostasis, ! cell cycle checkpoint GO:0000075 145 71 1,000 0,01781889 0,06318076 ! cAMP-mediated signaling GO:0019933 124 71 1,000 0,01781889 0,06308919 ! actin filament organization GO:0007015 167 72 1,000 0,01829414 0,06467811 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,01975176 0,06973056 GO:0090046|regulation of transcription regulator activity, ! phosphoinositide-mediated signaling GO:0048015 141 75 1,000 0,01975176 0,06962994 ! axon guidance GO:0007411 162 75 1,000 0,01975176 0,06952961 ! rhythmic process GO:0048511 142 75 1,000 0,01975176 0,06942956 ! tRNA transcription GO:0009304 17 7 0,000 0,01991733 0,06991098 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,01991733 0,06981068 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,01991733 0,06971067 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01991733 0,06961094 ! regulation of helicase activity GO:0051095 16 7 0,000 0,01991733 0,06951149 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,01991733 0,06941233 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,01991733 0,06931345 ! sleep GO:0030431 16 7 0,000 0,01991733 0,06921486 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01991733 0,06911654 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,01991733 0,0690185 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01991733 0,06892074 ! prostate gland development GO:0030850 14 7 0,000 0,01991733 0,06882326 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,01991733 0,06872605 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01991733 0,06862912 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01991733 0,06853246 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,01991733 0,06843607 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01991733 0,06833995 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,01991733 0,0682441 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,01991733 0,06814852 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01991733 0,06805321 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,01991733 0,06795816 ! glycolipid transport GO:0046836 11 7 0,000 0,01991733 0,06786338 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01991733 0,06776887 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,01991733 0,06767461 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,01991733 0,06758062 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01991733 0,06748689 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01991733 0,06739341 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,01991733 0,0673002 ! pericardium development GO:0060039 16 7 0,000 0,01991733 0,06720724 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,01991733 0,06711455 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,01991733 0,0670221 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,01991733 0,06692991 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,01991733 0,06683797 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01991733 0,06674629 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01991733 0,06665486 ! lipoprotein transport GO:0042953 14 7 0,000 0,01991733 0,06656367 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,01991733 0,06647274 ! rhythmic behavior GO:0007622 17 7 0,000 0,01991733 0,06638205 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,01991733 0,06629161 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,01991733 0,06620142 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,01991733 0,06611147 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,01991733 0,06602177 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01991733 0,06593231 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,01991733 0,06584309 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01991733 0,06575412 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,01991733 0,06566538 ! mechanosensory behavior GO:0007638 16 7 0,000 0,01991733 0,06557688 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,01991733 0,06548862 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,01991733 0,0654006 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,01991733 0,06531281 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,01991733 0,06522526 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01991733 0,06513795 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01991733 0,06505086 ! spinal cord patterning GO:0021511 14 7 0,000 0,01991733 0,06496401 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,01991733 0,06487739 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,01991733 0,06479101 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01991733 0,06470485 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,01991733 0,06461892 ! adrenal gland development GO:0030325 17 7 0,000 0,01991733 0,06453322 ! cysteine metabolic process GO:0006534 13 7 0,000 0,01991733 0,06444774 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,01991733 0,06436249 ! ovulation GO:0030728 10 7 0,000 0,01991733 0,06427747 ! adenohypophysis development GO:0021984 11 7 0,000 0,01991733 0,06419267 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,01991733 0,0641081 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,01991733 0,06402374 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,01991733 0,06393961 ! microtubule nucleation GO:0007020 21 7 0,000 0,01991733 0,0638557 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01991733 0,06377201 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,01991733 0,06368854 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01991733 0,06360529 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,01991733 0,06352225 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,01991733 0,06343943 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01991733 0,06335683 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,01991733 0,06327444 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,01991733 0,06319227 ! galactose metabolic process GO:0006012 13 7 0,000 0,01991733 0,06311031 ! vesicle fusion GO:0006906 20 7 0,000 0,01991733 0,06302856 ! response to dietary excess GO:0002021 8 7 0,000 0,01991733 0,06294702 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01991733 0,06286569 ! intracellular pH reduction GO:0051452 13 7 0,000 0,01991733 0,06278457 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01991733 0,06270367 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,01991733 0,06262297 ! organ growth GO:0035265 15 7 0,000 0,01991733 0,06254247 ! nucleoside transport GO:0015858 11 7 0,000 0,01991733 0,06246219 ! nucleoside salvage GO:0043174 11 7 0,000 0,01991733 0,06238211 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,01991733 0,06230223 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,01991733 0,06222256 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,01991733 0,0621431 ! parturition GO:0007567 16 7 0,000 0,01991733 0,06206383 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,01991733 0,06198477 ! rRNA modification GO:0000154 14 7 0,000 0,01991733 0,06190591 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,01991733 0,06182725 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,01991733 0,06174879 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,01991733 0,06167053 ! monocyte differentiation GO:0030224 16 7 0,000 0,01991733 0,06159246 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,01991733 0,0615146 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01991733 0,06143693 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,01991733 0,06135945 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,01991733 0,06128217 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,01991733 0,06120509 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01991733 0,0611282 ! fibrinolysis GO:0042730 11 7 0,000 0,01991733 0,0610515 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,01991733 0,06097499 ! eating behavior GO:0042755 8 7 0,000 0,01991733 0,06089868 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01991733 0,06082256 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01991733 0,06074662 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,01991733 0,06067088 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,01991733 0,06059532 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01991733 0,06051996 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,01991733 0,06044478 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01991733 0,06036978 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,01991733 0,06029498 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,01991733 0,06022035 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,01991733 0,06014592 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,01991733 0,06007166 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01991733 0,05999759 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,01991733 0,0599237 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01991733 0,05984999 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01991733 0,05977647 ! histone ubiquitination GO:0016574 9 7 0,000 0,01991733 0,05970312 ! regulation of meiosis GO:0040020 12 7 0,000 0,01991733 0,05962996 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,01991733 0,05955697 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01991733 0,05948416 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,01991733 0,05941153 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01991733 0,05933908 ! membrane to membrane docking GO:0022614 14 7 0,000 0,01991733 0,0592668 ! transcription termination GO:0006353 14 7 0,000 0,01991733 0,0591947 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01991733 0,05912278 ! anaphase GO:0051322 18 7 0,000 0,01991733 0,05905103 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,01991733 0,05897945 ! axonal fasciculation GO:0007413 19 7 0,000 0,01991733 0,05890805 ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,01991733 0,05883681 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,01991733 0,05876576 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,01991733 0,05869487 ! diuresis GO:0030146 12 7 0,000 0,01991733 0,05862415 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01991733 0,0585536 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01991733 0,05848323 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01991733 0,05841302 ! antibiotic transport GO:0042891 9 7 0,000 0,01991733 0,05834298 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01991733 0,05827311 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,01991733 0,0582034 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,01991733 0,05813387 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,01991733 0,05806449 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,01991733 0,05799529 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,01991733 0,05792624 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,01991733 0,05785737 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01991733 0,05778865 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01991733 0,0577201 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,01991733 0,05765171 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,01991733 0,05758349 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,01991733 0,05751542 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,01991733 0,05744752 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,01991733 0,05737977 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,01991733 0,05731219 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,01991733 0,05724476 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,01991733 0,05717749 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,01991733 0,05711038 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01991733 0,05704343 ! muscle adaptation GO:0043500 13 7 0,000 0,01991733 0,05697663 ! embryonic heart tube development GO:0035050 14 7 0,000 0,01991733 0,05690999 ! retina homeostasis GO:0001895 12 7 0,000 0,01991733 0,05684351 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,01991733 0,05677718 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,01991733 0,05671101 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,01991733 0,05664499 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,01991733 0,05657912 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,02024815 0,05745205 ! phosphoinositide metabolic process GO:0030384 146 77 1,000 0,02074973 0,05880695 ! protein oligomerization GO:0051259 149 79 1,000 0,02176837 0,0616224 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,02273041 0,0642713 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,02273041 0,06419699 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,02273041 0,06412286 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,02273041 0,0640489 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,02273041 0,06397512 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02273041 0,0639015 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02273041 0,06382805 ! male meiosis GO:0007140 9 8 0,000 0,02273041 0,06375476 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,02273041 0,06368165 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,02273041 0,06360871 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,02273041 0,06353593 ! meiotic prophase I GO:0007128 14 8 0,000 0,02273041 0,06346331 ! response to zinc ion GO:0010043 12 8 0,000 0,02273041 0,06339087 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,02273041 0,06331859 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02273041 0,06324647 ! oligopeptide transport GO:0006857 16 8 0,000 0,02273041 0,06317452 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,02273041 0,06310273 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,02273041 0,0630311 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,02273041 0,06295964 ! signal peptide processing GO:0006465 12 8 0,000 0,02273041 0,06288834 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,02273041 0,06281719 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,02273041 0,06274621 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02273041 0,0626754 ! succinate metabolic process GO:0006105 17 8 0,000 0,02273041 0,06260474 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,02273041 0,06253423 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,02273041 0,06246389 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02273041 0,06239371 ! estrogen metabolic process GO:0008210 17 8 0,000 0,02273041 0,06232368 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,02273041 0,06225381 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,02273041 0,0621841 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02273041 0,06211454 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02273041 0,06204514 ! reflex GO:0060004 17 8 0,000 0,02273041 0,06197589 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02273041 0,0619068 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,02273041 0,06183786 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,02273041 0,06176908 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02273041 0,06170044 ! pigment granule organization GO:0048753 17 8 0,000 0,02273041 0,06163196 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02273041 0,06156364 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,02273041 0,06149546 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,02273041 0,06142743 ! astrocyte differentiation GO:0048708 19 8 0,000 0,02273041 0,06135956 ! histidine catabolic process GO:0006548 10 8 0,000 0,02273041 0,06129183 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02273041 0,06122426 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,02273041 0,06115683 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,02273041 0,06108955 GO:0006559|L-phenylalanine catabolic process, ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,02273041 0,06102242 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,02273041 0,06095543 ! melanin metabolic process GO:0006582 17 8 0,000 0,02273041 0,0608886 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,02273041 0,06082191 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,02273041 0,06075536 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,02273041 0,06068896 ! macrophage activation GO:0042116 13 8 0,000 0,02273041 0,06062271 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02273041 0,0605566 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02273041 0,06049063 ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,02273041 0,06042481 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,02273041 0,06035913 ! purine salvage GO:0043101 12 8 0,000 0,02273041 0,06029359 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,02273041 0,0602282 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,02273041 0,06016295 ! osteoblast development GO:0002076 17 8 0,000 0,02273041 0,06009784 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,02273041 0,06003287 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,02273041 0,05996803 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,02273041 0,05990334 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,02273041 0,05983879 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02273041 0,05977438 ! response to UV-B GO:0010224 17 8 0,000 0,02273041 0,05971011 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,02273041 0,05964597 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02273041 0,05958197 ! intermediate filament organization GO:0045109 12 8 0,000 0,02273041 0,05951811 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,02273041 0,05945439 ! cellular extravasation GO:0045123 13 8 0,000 0,02273041 0,0593908 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,02273041 0,05932735 ! response to antibiotic GO:0046677 11 8 0,000 0,02273041 0,05926403 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,02273041 0,05920085 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,02273041 0,05913781 ! DNA topological change GO:0006265 12 8 0,000 0,02273041 0,05907489 ! response to tropane GO:0014073 15 8 0,000 0,02273041 0,05901212 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,02273041 0,05894947 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,02273041 0,05888696 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02273041 0,05882458 ! mast cell activation GO:0045576 14 8 0,000 0,02273041 0,05876233 ! multicellular organismal aging GO:0010259 20 8 0,000 0,02273041 0,05870021 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,02273041 0,05863823 ! gas homeostasis GO:0033483 14 8 0,000 0,02273041 0,05857637 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,02273041 0,05851465 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,02273041 0,05845305 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,02273041 0,05839159 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02273041 0,05833025 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02273041 0,05826905 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,02273041 0,05820797 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02273041 0,05814702 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,02273041 0,05808619 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,02273041 0,0580255 ! intracellular lipid transport GO:0032365 16 8 0,000 0,02273041 0,05796493 ! response to tumor cell GO:0002347 16 8 0,000 0,02273041 0,05790448 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02273041 0,05784417 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,02273041 0,05778398 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,02273041 0,05772391 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02273041 0,05766397 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,02273041 0,05760415 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,02273041 0,05754446 ! hormone catabolic process GO:0042447 17 8 0,000 0,02273041 0,05748489 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,02273041 0,05742544 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,02273041 0,05736612 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,02273041 0,05730691 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,02273041 0,05724784 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02273041 0,05718888 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,02273041 0,05713004 ! adult feeding behavior GO:0008343 10 8 0,000 0,02273041 0,05707133 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,02273041 0,05701273 ! ATP catabolic process GO:0006200 11 8 0,000 0,02273041 0,05695426 ! blastocyst growth GO:0001832 19 8 0,000 0,02273041 0,0568959 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02273041 0,05683767 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02273041 0,05677955 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,02273041 0,05672155 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02273041 0,05666367 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,02273041 0,05660591 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,02273041 0,05654827 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,02273041 0,05649074 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,02273041 0,05643333 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,02273041 0,05637604 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,02273041 0,05631886 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02273041 0,0562618 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,02273041 0,05620486 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,02273041 0,05614803 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02273041 0,05609131 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,02273041 0,05603471 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,02273041 0,05597823 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,02273041 0,05592185 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,02273041 0,05586559 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,02273041 0,05580945 ! response to hypoxia GO:0001666 178 81 1,000 0,02280742 0,05594229 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,02333451 0,05717774 ! regulation of adenylate cyclase activity GO:0045761 165 83 1,000 0,0238666 0,05842295 ! response to oxygen levels GO:0070482 183 83 1,000 0,0238666 0,05836447 ! regulation of cyclase activity GO:0031279 168 85 1,000 0,02494567 0,06094227 ! regulation of cAMP biosynthetic process GO:0030817 173 86 1,000 0,02549257 0,06221614 ! regulation of lyase activity GO:0051339 169 86 1,000 0,02549257 0,06215405 ! axon extension GO:0048675 16 9 0,000 0,0255355 0,06219663 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,0255355 0,06213468 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,0255355 0,06207286 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0255355 0,06201116 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,0255355 0,06194958 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,0255355 0,06188812 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,0255355 0,06182678 ! reproductive behavior GO:0019098 22 9 0,000 0,0255355 0,06176557 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0255355 0,06170447 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,0255355 0,0616435 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,0255355 0,06158265 ! UTP metabolic process GO:0046051 10 9 0,000 0,0255355 0,06152192 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,0255355 0,0614613 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,0255355 0,06140081 ! artery development GO:0060840 25 9 0,000 0,0255355 0,06134044 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,0255355 0,06128018 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,0255355 0,06122004 ! equilibrioception GO:0050957 20 9 0,000 0,0255355 0,06116002 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,0255355 0,06110012 ! chemosensory behavior GO:0007635 21 9 0,000 0,0255355 0,06104034 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,0255355 0,06098067 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,0255355 0,06092112 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0255355 0,06086168 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,0255355 0,06080236 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,0255355 0,06074316 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,0255355 0,06068407 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,0255355 0,06062509 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,0255355 0,06056624 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0255355 0,06050749 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,0255355 0,06044886 ! protein targeting to ER GO:0045047 25 9 0,000 0,0255355 0,06039034 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,0255355 0,06033194 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,0255355 0,06027365 ! T cell selection GO:0045058 27 9 0,000 0,0255355 0,06021547 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,0255355 0,0601574 ! glycine catabolic process GO:0006546 15 9 0,000 0,0255355 0,06009944 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,0255355 0,0600416 ! endosome organization GO:0007032 20 9 0,000 0,0255355 0,05998387 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0255355 0,05992625 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,0255355 0,05986874 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0255355 0,05981134 ! mannose metabolic process GO:0006013 13 9 0,000 0,0255355 0,05975404 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,0255355 0,05969686 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,0255355 0,05963979 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,0255355 0,05958283 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,0255355 0,05952598 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,0255355 0,05946923 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0255355 0,05941259 ! retinol metabolic process GO:0042572 20 9 0,000 0,0255355 0,05935606 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,0255355 0,05929964 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,0255355 0,05924333 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,0255355 0,05918712 ! macrophage differentiation GO:0030225 15 9 0,000 0,0255355 0,05913102 ! oligodendrocyte development GO:0014003 11 9 0,000 0,0255355 0,05907502 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,0255355 0,05901913 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0255355 0,05896335 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,0255355 0,05890767 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0255355 0,0588521 ! response to amine stimulus GO:0014075 13 9 0,000 0,0255355 0,05879663 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0255355 0,05874126 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,0255355 0,058686 ! erythrocyte development GO:0048821 17 9 0,000 0,0255355 0,05863085 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,0255355 0,0585758 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,0255355 0,05852085 ! renal water homeostasis GO:0003091 15 9 0,000 0,0255355 0,058466 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,0255355 0,05841126 ! icosanoid secretion GO:0032309 15 9 0,000 0,0255355 0,05835662 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0255355 0,05830208 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,0255355 0,05824764 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,0255355 0,0581933 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,0255355 0,05813907 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,0255355 0,05808494 ! sterol catabolic process GO:0016127 14 9 0,000 0,0255355 0,0580309 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,0255355 0,05797697 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,0255355 0,05792314 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,0255355 0,05786941 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,0255355 0,05781578 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,0255355 0,05776224 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,0255355 0,05770881 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,0255355 0,05765547 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,0255355 0,05760224 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,0255355 0,0575491 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,0255355 0,05749606 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0255355 0,05744311 ! purine base metabolic process GO:0006144 25 9 0,000 0,0255355 0,05739027 ! pigment granule transport GO:0051904 17 9 0,000 0,0255355 0,05733752 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,0255355 0,05728487 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,0255355 0,05723231 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,0255355 0,05717986 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,0255355 0,05712749 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,0255355 0,05707523 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,0255355 0,05702306 ! mitochondrion localization GO:0051646 18 9 0,000 0,0255355 0,05697098 ! regulation of cAMP metabolic process GO:0030814 182 89 1,000 0,02716241 0,06054541 ! regulation of DNA binding GO:0051101 167 89 1,000 0,02716241 0,06049022 ! regulation of cell cycle process GO:0010564 161 90 1,000 0,02772862 0,06169492 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 1,000 0,02829958 0,06290799 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! ossification GO:0001503 205 91 1,000 0,02829958 0,0628508 ! gland development GO:0048732 220 91 1,000 0,02829958 0,06279371 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,02833261 0,06280995 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 0,000 0,02833261 0,06275301 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,02833261 0,06269617 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02833261 0,06263943 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,02833261 0,06258279 ! associative learning GO:0008306 21 10 0,000 0,02833261 0,06252626 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,02833261 0,06246983 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02833261 0,0624135 ! phosphate transport GO:0006817 24 10 0,000 0,02833261 0,06235727 ! cell volume homeostasis GO:0006884 17 10 0,000 0,02833261 0,06230114 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 0,000 0,02833261 0,06224511 ! CTP metabolic process GO:0046036 11 10 0,000 0,02833261 0,06218919 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,02833261 0,06213336 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02833261 0,06207764 ! GTP metabolic process GO:0046039 11 10 0,000 0,02833261 0,06202201 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,02833261 0,06196649 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,02833261 0,06191106 ! social behavior GO:0035176 29 10 0,000 0,02833261 0,06185574 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,02833261 0,06180051 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,02833261 0,06174538 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,02833261 0,06169035 ! androgen metabolic process GO:0008209 17 10 0,000 0,02833261 0,06163541 ! phospholipid efflux GO:0033700 19 10 0,000 0,02833261 0,06158058 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02833261 0,06152584 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,02833261 0,0614712 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,02833261 0,06141665 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,02833261 0,06136221 ! pathogenesis GO:0009405 17 10 0,000 0,02833261 0,06130785 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02833261 0,0612536 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,02833261 0,06119944 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,02833261 0,06114538 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,02833261 0,06109141 ! endoderm development GO:0007492 18 10 0,000 0,02833261 0,06103754 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,02833261 0,06098376 ! arginine catabolic process GO:0006527 17 10 0,000 0,02833261 0,06093008 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02833261 0,06087649 ! proline metabolic process GO:0006560 13 10 0,000 0,02833261 0,06082299 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02833261 0,06076959 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,02833261 0,06071629 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,02833261 0,06066307 ! V(D)J recombination GO:0033151 34 10 0,000 0,02833261 0,06060995 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,02833261 0,06055693 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,02833261 0,06050399 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,02833261 0,06045115 ! B cell proliferation GO:0042100 19 10 0,000 0,02833261 0,0603984 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,02833261 0,06034574 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,02833261 0,06029318 ! multicellular organism growth GO:0035264 19 10 0,000 0,02833261 0,0602407 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,02833261 0,06018832 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,02833261 0,06013603 ! ruffle organization GO:0031529 17 10 0,000 0,02833261 0,06008383 ! epithelial cell development GO:0002064 21 10 0,000 0,02833261 0,06003172 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,02833261 0,05997969 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02833261 0,05992776 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,02833261 0,05987592 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,02833261 0,05982417 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,02833261 0,05977251 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,02833261 0,05972094 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,02833261 0,05966945 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02833261 0,05961806 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,02833261 0,05956675 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,02833261 0,05951554 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,02833261 0,05946441 ! segment specification GO:0007379 15 10 0,000 0,02833261 0,05941336 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,02833261 0,05936241 ! blastoderm segmentation GO:0007350 19 10 0,000 0,02833261 0,05931154 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,02833261 0,05926076 ! response to dsRNA GO:0043331 23 10 0,000 0,02833261 0,05921007 ! DNA ligation GO:0006266 18 10 0,000 0,02833261 0,05915946 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,02833261 0,05910894 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02833261 0,0590585 ! melanosome localization GO:0032400 16 10 0,000 0,02833261 0,05900816 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,02833261 0,05895789 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,02833261 0,05890772 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,02833261 0,05885763 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02833261 0,05880762 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,02833261 0,0587577 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,02833261 0,05870786 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,02833261 0,05865811 ! protein sumoylation GO:0016925 17 10 0,000 0,02833261 0,05860844 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,02833261 0,05855886 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02833261 0,05850936 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02833261 0,05845994 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02833261 0,05841061 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,02833261 0,05836136 ! salivary gland development GO:0007431 28 10 0,000 0,02833261 0,05831219 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,02833261 0,0582631 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,02833261 0,0582141 ! midbrain development GO:0030901 14 10 0,000 0,02833261 0,05816518 ! musculoskeletal movement GO:0050881 16 10 0,000 0,02833261 0,05811635 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,02833261 0,05806759 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,02833261 0,05801892 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,02833261 0,05797032 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,02833261 0,05792181 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,02833261 0,05787338 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02833261 0,05782504 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02833261 0,05777677 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,02833261 0,05772858 ! detection of calcium ion GO:0005513 24 10 0,000 0,02833261 0,05768047 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02833261 0,05763245 ! blastocyst formation GO:0001825 18 10 0,000 0,02833261 0,0575845 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,02833261 0,05753663 ! cerebellar cortex development GO:0021695 16 10 0,000 0,02833261 0,05748884 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,02833261 0,05744113 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,02833261 0,05739351 ! response to nicotine GO:0035094 20 10 0,000 0,02833261 0,05734595 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,02833261 0,05729848 ! bone development GO:0060348 206 92 1,000 0,02887526 0,0583476 ! regulation of cell adhesion GO:0030155 241 92 1,000 0,02887526 0,05829938 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,02945561 0,05942202 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,03004063 0,06055218 ! regulation of membrane potential GO:0042391 179 94 1,000 0,03004063 0,06050226 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 1,000 0,03063026 0,06163898 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,03063026 0,06158825 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,03112177 0,06252507 ! respiratory burst GO:0045730 17 11 0,000 0,03112177 0,0624737 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,03112177 0,06242241 ! neuron fate specification GO:0048665 18 11 0,000 0,03112177 0,0623712 ! telencephalon cell migration GO:0022029 23 11 0,000 0,03112177 0,06232007 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,03112177 0,06226903 ! thyroid gland development GO:0030878 26 11 0,000 0,03112177 0,06221808 ! synapsis GO:0007129 14 11 0,000 0,03112177 0,0621672 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,03112177 0,06211641 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,03112177 0,06206571 ! response to pain GO:0048265 27 11 0,000 0,03112177 0,06201508 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,03112177 0,06196454 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,03112177 0,06191408 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 0,000 0,03112177 0,0618637 GO:0010812|negative regulation of cell-substrate adhesion, ! bone resorption GO:0045453 16 11 0,000 0,03112177 0,06181341 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,03112177 0,06176319 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,03112177 0,06171306 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,03112177 0,06166301 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,03112177 0,06161304 ! melanocyte differentiation GO:0030318 20 11 0,000 0,03112177 0,06156315 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,03112177 0,06151334 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,03112177 0,06146361 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,03112177 0,06141397 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,03112177 0,0613644 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,03112177 0,06131491 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,03112177 0,0612655 ! UV protection GO:0009650 20 11 0,000 0,03112177 0,06121618 ! adult heart development GO:0007512 16 11 0,000 0,03112177 0,06116693 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,03112177 0,06111776 ! macroautophagy GO:0016236 19 11 0,000 0,03112177 0,06106867 ! temperature homeostasis GO:0001659 18 11 0,000 0,03112177 0,06101965 ! behavioral fear response GO:0001662 27 11 0,000 0,03112177 0,06097072 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,03112177 0,06092187 ! negative regulation of ossification GO:0030279 27 11 0,000 0,03112177 0,06087309 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,03112177 0,06082439 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,03112177 0,06077577 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,03112177 0,06072723 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,03112177 0,06067876 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,03112177 0,06063037 ! regulation of organ growth GO:0046620 14 11 0,000 0,03112177 0,06058206 ! pigment granule localization GO:0051875 20 11 0,000 0,03112177 0,06053383 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,03112177 0,06048567 ! vasoconstriction GO:0042310 20 11 0,000 0,03112177 0,06043759 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,03112177 0,06038959 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,03112177 0,06034166 ! embryonic axis specification GO:0000578 19 11 0,000 0,03112177 0,06029381 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,03112177 0,06024603 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,03112177 0,06019833 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,03112177 0,0601507 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,03112177 0,06010315 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,03112177 0,06005568 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,03112177 0,06000828 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,03112177 0,05996095 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,03112177 0,0599137 ! prophase GO:0051324 17 11 0,000 0,03112177 0,05986653 ! neuroblast proliferation GO:0007405 25 11 0,000 0,03112177 0,05981943 ! nucleosome positioning GO:0016584 15 11 0,000 0,03112177 0,0597724 ! regulation of isotype switching GO:0045191 24 11 0,000 0,03112177 0,05972544 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,03112177 0,05967856 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,03112177 0,05963176 ! apical protein localization GO:0045176 18 11 0,000 0,03112177 0,05958502 ! acid secretion GO:0046717 20 11 0,000 0,03112177 0,05953836 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,03112177 0,05949178 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,03112177 0,05944526 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,03112177 0,05939882 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,03112177 0,05935245 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,03112177 0,05930615 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,03112177 0,05925993 ! cholesterol efflux GO:0033344 21 11 0,000 0,03112177 0,05921378 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,03112177 0,0591677 ! oocyte development GO:0048599 20 11 0,000 0,03112177 0,05912169 ! germ cell migration GO:0008354 26 11 0,000 0,03112177 0,05907575 ! embryonic gut development GO:0048566 19 11 0,000 0,03112177 0,05902988 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,03112177 0,05898409 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,03112177 0,05893836 ! activation of innate immune response GO:0002218 16 11 0,000 0,03112177 0,05889271 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,03112177 0,05884713 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,03112177 0,05880162 ! lysogeny GO:0030069 22 11 0,000 0,03112177 0,05875617 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,03112177 0,0587108 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,03112177 0,0586655 ! sequestering of metal ion GO:0051238 15 11 0,000 0,03112177 0,05862027 ! nucleus localization GO:0051647 22 11 0,000 0,03112177 0,05857511 ! regulation of T cell activation GO:0050863 175 96 1,000 0,03122449 0,05872318 ! regulation of DNA metabolic process GO:0051052 188 97 1,000 0,03182327 0,05980327 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,03242659 0,06089021 ! skeletal muscle tissue development GO:0007519 223 100 1,000 0,03364669 0,06313278 GO:0060538|skeletal muscle organ development, ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,03390301 0,06356488 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,03390301 0,06351614 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,03390301 0,06346747 ! regulation of B cell proliferation GO:0030888 22 12 0,000 0,03390301 0,06341887 ! mating GO:0007618 17 12 0,000 0,03390301 0,06337035 ! protein complex disassembly GO:0043241 28 12 0,000 0,03390301 0,0633219 GO:0043624|cellular protein complex disassembly, ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,03390301 0,06327352 ! hippocampus development GO:0021766 29 12 0,000 0,03390301 0,06322522 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,03390301 0,063177 ! T cell proliferation GO:0042098 32 12 0,000 0,03390301 0,06312884 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03390301 0,06308076 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,03390301 0,06303276 ! ventral spinal cord development GO:0021517 25 12 0,000 0,03390301 0,06298482 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,03390301 0,06293696 ! drug transport GO:0015893 16 12 0,000 0,03390301 0,06288918 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,03390301 0,06284146 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,03390301 0,06279382 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,03390301 0,06274625 ! polyamine metabolic process GO:0006595 18 12 0,000 0,03390301 0,06269875 ! focal adhesion formation GO:0048041 37 12 0,000 0,03390301 0,06265132 ! mitotic spindle organization GO:0007052 23 12 0,000 0,03390301 0,06260396 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,03390301 0,06255668 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,03390301 0,06250947 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,03390301 0,06246233 ! lipid digestion GO:0044241 21 12 0,000 0,03390301 0,06241526 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,03390301 0,06236826 ! entry into host cell GO:0030260 34 12 0,000 0,03390301 0,06232133 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03390301 0,06227447 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,03390301 0,06222768 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,03390301 0,06218096 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03390301 0,06213432 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,03390301 0,06208774 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,03390301 0,06204123 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,03390301 0,06199479 ! snRNA metabolic process GO:0016073 30 12 0,000 0,03390301 0,06194842 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,03390301 0,06190213 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,03390301 0,0618559 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03390301 0,06180973 ! cranial nerve development GO:0021545 23 12 0,000 0,03390301 0,06176364 ! fucose catabolic process GO:0019317 25 12 0,000 0,03390301 0,06171762 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,03390301 0,06167166 ! histone acetylation GO:0016573 27 12 0,000 0,03390301 0,06162578 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,03390301 0,06157996 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03390301 0,06153421 ! regulation of hormone metabolic process GO:0032350 28 12 0,000 0,03390301 0,06148853 ! zymogen activation GO:0031638 18 12 0,000 0,03390301 0,06144291 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,03390301 0,06139736 ! T cell homeostasis GO:0043029 28 12 0,000 0,03390301 0,06135188 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,03390301 0,06130647 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,03390301 0,06126113 ! oocyte differentiation GO:0009994 21 12 0,000 0,03390301 0,06121585 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,03390301 0,06117064 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,03390301 0,06112549 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,03390301 0,06108042 ! defense response to fungus GO:0050832 15 12 0,000 0,03390301 0,0610354 ! embryonic placenta development GO:0001892 21 12 0,000 0,03390301 0,06099046 ! lamellipodium assembly GO:0030032 24 12 0,000 0,03390301 0,06094558 ! response to cold GO:0009409 17 12 0,000 0,03390301 0,06090077 ! establishment of cell polarity GO:0030010 21 12 0,000 0,03390301 0,06085602 ! regulation of synapse organization GO:0050807 18 12 0,000 0,03390301 0,06081134 ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,03667633 0,06573755 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03667633 0,06568936 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,03667633 0,06564123 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03667633 0,06559318 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,03667633 0,0655452 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,03667633 0,06549728 ! peroxisomal transport GO:0043574 28 13 0,000 0,03667633 0,06544944 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,03667633 0,06540167 ! cartilage condensation GO:0001502 22 13 0,000 0,03667633 0,06535396 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,03667633 0,06530633 ! organelle fusion GO:0048284 36 13 0,000 0,03667633 0,06525877 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,03667633 0,06521127 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,03667633 0,06516384 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,03667633 0,06511649 ! endocrine pancreas development GO:0031018 25 13 0,000 0,03667633 0,0650692 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,03667633 0,06502198 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,03667633 0,06497483 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,03667633 0,06492774 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,03667633 0,06488073 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,03667633 0,06483378 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03667633 0,0647869 ! methionine metabolic process GO:0006555 31 13 0,000 0,03667633 0,06474009 ! plasma membrane organization GO:0007009 27 13 0,000 0,03667633 0,06469335 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,03667633 0,06464667 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,03667633 0,06460006 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,03667633 0,06455352 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,03667633 0,06450704 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! response to X-ray GO:0010165 28 13 0,000 0,03667633 0,06446064 ! cytokine metabolic process GO:0042107 24 13 0,000 0,03667633 0,0644143 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,03667633 0,06436802 ! exocrine system development GO:0035272 34 13 0,000 0,03667633 0,06432181 ! asymmetric protein localization GO:0008105 24 13 0,000 0,03667633 0,06427567 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,03667633 0,06422959 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,03667633 0,06418358 ! L-glutamate transport GO:0015813 30 13 0,000 0,03667633 0,06413764 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,03667633 0,06409176 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,03667633 0,06404595 ! protein homotetramerization GO:0051289 24 13 0,000 0,03667633 0,0640002 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,03667633 0,06395452 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,03667633 0,0639089 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,03667633 0,06386335 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,03667633 0,06381787 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,03667633 0,06377244 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03667633 0,06372709 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,03667633 0,06368179 ! histone methylation GO:0016571 29 13 0,000 0,03667633 0,06363657 ! chromatin silencing GO:0006342 29 13 0,000 0,03667633 0,0635914 ! gland morphogenesis GO:0022612 31 13 0,000 0,03667633 0,0635463 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,03667633 0,06350126 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,03667633 0,06345629 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03667633 0,06341138 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,03667633 0,06336654 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,03667633 0,06332176 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,03667633 0,06327704 ! spleen development GO:0048536 24 13 0,000 0,03667633 0,06323238 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,03667633 0,06318779 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,03667633 0,06314326 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,03667633 0,06309879 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,03667633 0,06305439 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03667633 0,06301005 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,03667633 0,06296577 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,03667633 0,06292155 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,03667633 0,06287739 ! insulin secretion GO:0030073 24 13 0,000 0,03667633 0,0628333 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,03667633 0,06278927 ! acrosome reaction GO:0007340 19 13 0,000 0,03667633 0,0627453 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,03667633 0,06270139 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,03667633 0,06265754 ! rRNA transcription GO:0009303 28 14 0,000 0,03944178 0,06733492 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,03944178 0,0672879 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,03944178 0,06724094 ! water transport GO:0006833 21 14 0,000 0,03944178 0,06719405 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,03944178 0,06714722 ! non-recombinational repair GO:0000726 29 14 0,000 0,03944178 0,06710046 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,03944178 0,06705377 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,03944178 0,06700714 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,03944178 0,06696057 ! RNA polyadenylation GO:0043631 32 14 0,000 0,03944178 0,06691407 ! lipid localization GO:0010876 32 14 0,000 0,03944178 0,06686764 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,03944178 0,06682127 ! regulated secretory pathway GO:0045055 24 14 0,000 0,03944178 0,06677496 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,03944178 0,06672872 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,03944178 0,06668254 ! arginine metabolic process GO:0006525 21 14 0,000 0,03944178 0,06663642 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,03944178 0,06659037 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,03944178 0,06654438 ! regulation of heart rate GO:0002027 25 14 0,000 0,03944178 0,06649846 ! fear response GO:0042596 34 14 0,000 0,03944178 0,0664526 ! organic alcohol transport GO:0015850 29 14 0,000 0,03944178 0,0664068 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,03944178 0,06636106 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,03944178 0,06631539 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03944178 0,06626978 ! neutral amino acid transport GO:0015804 28 14 0,000 0,03944178 0,06622424 ! bone mineralization GO:0030282 18 14 0,000 0,03944178 0,06617875 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,03944178 0,06613333 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,03944178 0,06608797 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,03944178 0,06604268 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,03944178 0,06599744 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,03944178 0,06595227 ! regulation of cellular pH GO:0030641 27 14 0,000 0,03944178 0,06590716 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,03944178 0,06586211 ! ribosome assembly GO:0042255 18 14 0,000 0,03944178 0,06581712 ! cerebellum development GO:0021549 23 14 0,000 0,03944178 0,06577219 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,03944178 0,06572733 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,03944178 0,06568253 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,03944178 0,06563778 ! response to gamma radiation GO:0010332 30 14 0,000 0,03944178 0,0655931 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,03944178 0,06554848 ! NADP metabolic process GO:0006739 24 14 0,000 0,03944178 0,06550392 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,03944178 0,06545942 ! oxygen transport GO:0015671 22 14 0,000 0,03944178 0,06541498 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03944178 0,0653706 ! male genitalia development GO:0030539 26 14 0,000 0,03944178 0,06532628 ! regulation of axon extension GO:0030516 43 14 0,000 0,03944178 0,06528202 ! release of cytochrome c from mitochondria GO:0001836 31 14 0,000 0,03944178 0,06523782 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,03944178 0,06519368 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,03944178 0,0651496 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,04219936 0,06965746 ! lactation GO:0007595 30 15 0,000 0,04219936 0,06961043 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,04219936 0,06956346 ! reproductive cellular process GO:0048610 22 15 0,000 0,04219936 0,06951655 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,04219936 0,0694697 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,04219936 0,06942292 ! superoxide anion generation GO:0042554 22 15 0,000 0,04219936 0,06937621 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,04219936 0,06932955 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,04219936 0,06928296 ! copper ion transport GO:0006825 22 15 0,000 0,04219936 0,06923643 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,04219936 0,06918996 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,04219936 0,06914356 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,04219936 0,06909721 ! sulfate transport GO:0008272 27 15 0,000 0,04219936 0,06905093 ! response to cAMP GO:0051591 25 15 0,000 0,04219936 0,06900471 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,04219936 0,06895856 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,04219936 0,06891246 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,04219936 0,06886643 ! response to hexose stimulus GO:0009746 25 15 0,000 0,04219936 0,06882046 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,04219936 0,06877454 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,04219936 0,06872869 ! vesicle coating GO:0006901 38 15 0,000 0,04219936 0,06868291 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,04219936 0,06863718 ! regulation of exocytosis GO:0017157 26 15 0,000 0,04219936 0,06859151 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,04219936 0,06854591 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,04219936 0,06850036 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,04219936 0,06845488 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,04219936 0,06840945 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,04219936 0,06836409 ! regulation of vasodilation GO:0042312 27 15 0,000 0,04219936 0,06831878 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,04219936 0,06827354 ! histone deacetylation GO:0016575 24 15 0,000 0,04219936 0,06822835 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,04219936 0,06818323 ! water homeostasis GO:0030104 28 15 0,000 0,04219936 0,06813816 ! cofactor transport GO:0051181 30 15 0,000 0,04219936 0,06809316 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,04219936 0,06804821 ! muscle maintenance GO:0046716 26 15 0,000 0,04219936 0,06800333 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,04219936 0,0679585 ! intestinal absorption GO:0050892 31 15 0,000 0,04219936 0,06791373 ! dopamine metabolic process GO:0042417 35 15 0,000 0,04219936 0,06786902 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,04219936 0,06782437 ! heme biosynthetic process GO:0006783 33 15 0,000 0,04219936 0,06777978 ! cell killing GO:0001906 32 15 0,000 0,04219936 0,06773524 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,04219936 0,06769077 ! epithelial to mesenchymal transition GO:0001837 30 15 0,000 0,04219936 0,06764635 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,04219936 0,06760199 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,04219936 0,06755769 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,04219936 0,06751345 ! actin filament polymerization GO:0030041 27 15 0,000 0,04219936 0,06746927 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,04219936 0,06742514 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,04494911 0,07177168 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,04494911 0,0717248 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,04494911 0,07167798 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,04494911 0,07163122 ! bone remodeling GO:0046849 28 16 0,000 0,04494911 0,07158453 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,04494911 0,07153789 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,04494911 0,07149132 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,04494911 0,07144481 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,04494911 0,07139835 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,04494911 0,07135196 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,04494911 0,07130563 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,04494911 0,07125936 ! startle response GO:0001964 28 16 0,000 0,04494911 0,07121314 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,04494911 0,07116699 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,04494911 0,0711209 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,04494911 0,07107487 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,04494911 0,07102889 ! protein polyubiquitination GO:0000209 41 16 0,000 0,04494911 0,07098298 ! glutamate metabolic process GO:0006536 25 16 0,000 0,04494911 0,07093712 ! pituitary gland development GO:0021983 30 16 0,000 0,04494911 0,07089133 ! response to osmotic stress GO:0006970 27 16 0,000 0,04494911 0,07084559 ! lysosomal transport GO:0007041 31 16 0,000 0,04494911 0,07079991 ! fructose metabolic process GO:0006000 25 16 0,000 0,04494911 0,0707543 ! L-amino acid transport GO:0015807 33 16 0,000 0,04494911 0,07070874 ! stem cell development GO:0048864 46 16 0,000 0,04494911 0,07066324 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04494911 0,07061779 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04494911 0,07057241 ! intermediate filament-based process GO:0045103 36 16 0,000 0,04494911 0,07052708 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,04494911 0,07048181 ! negative regulation of immune response GO:0050777 38 16 0,000 0,04494911 0,07043661 ! axon cargo transport GO:0008088 46 16 0,000 0,04494911 0,07039145 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,04494911 0,07034636 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,04494911 0,07030132 ! DNA replication initiation GO:0006270 28 16 0,000 0,04494911 0,07025635 ! neuron recognition GO:0008038 40 16 0,000 0,04494911 0,07021142 ! mRNA splice site selection GO:0006376 44 16 0,000 0,04494911 0,07016656 ! tissue regeneration GO:0042246 27 16 0,000 0,04494911 0,07012175 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,04494911 0,07007701 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,04494911 0,07003231 ! biomineral formation GO:0031214 22 16 0,000 0,04494911 0,06998768 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,04494911 0,0699431 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,04494911 0,06989858 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,04494911 0,06985411 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04494911 0,06980971 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,04494911 0,06976535 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,04494911 0,06972106 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,04494911 0,06967682 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,04494911 0,06963264 ! peptide hormone processing GO:0016486 27 16 0,000 0,04494911 0,06958851 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,04769103 0,0737867 ! metencephalon development GO:0022037 32 17 0,000 0,04769103 0,07374 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,04769103 0,07369336 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,04769103 0,07364677 ! filopodium assembly GO:0046847 42 17 0,000 0,04769103 0,07360025 ! endothelial cell migration GO:0043542 31 17 0,000 0,04769103 0,07355379 ! gene silencing by RNA GO:0031047 38 17 0,000 0,04769103 0,07350738 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,04769103 0,07346103 ! glial cell development GO:0021782 28 17 0,000 0,04769103 0,07341474 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,04769103 0,07336851 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,04769103 0,07332234 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,04769103 0,07327622 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,04769103 0,07323017 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,04769103 0,07318417 ! myoblast differentiation GO:0045445 50 17 0,000 0,04769103 0,07313823 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,04769103 0,07309234 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,04769103 0,07304652 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,04769103 0,07300075 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,04769103 0,07295504 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,04769103 0,07290938 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,04769103 0,07286379 ! NAD metabolic process GO:0019674 33 17 0,000 0,04769103 0,07281825 ! membrane budding GO:0006900 42 17 0,000 0,04769103 0,07277276 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,04769103 0,07272734 ! regulation of protein binding GO:0043393 33 17 0,000 0,04769103 0,07268197 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,04769103 0,07263666 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,04769103 0,0725914 ! genitalia development GO:0048806 32 17 0,000 0,04769103 0,0725462 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,04769103 0,07250106 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 0,000 0,04769103 0,07245597 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,04769103 0,07241094 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,04769103 0,07236596 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,04769103 0,07232104 ! steroid catabolic process GO:0006706 34 17 0,000 0,04769103 0,07227618 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,04769103 0,07223137 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,04769103 0,07218661 ! gas transport GO:0015669 26 17 0,000 0,04769103 0,07214192 ! organic cation transport GO:0015695 32 17 0,000 0,04769103 0,07209727 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,04769103 0,07205269 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,04769103 0,07200816 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,05042517 0,07608936 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,05042517 0,0760424 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,05042517 0,07599548 ! limbic system development GO:0021761 40 18 0,000 0,05042517 0,07594863 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,05042517 0,07590184 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,05042517 0,0758551 ! adult walking behavior GO:0007628 36 18 0,000 0,05042517 0,07580842 ! patterning of blood vessels GO:0001569 43 18 0,000 0,05042517 0,0757618 ! heart looping GO:0001947 34 18 0,000 0,05042517 0,07571523 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,05042517 0,07566872 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,05042517 0,07562227 ! centrosome cycle GO:0007098 26 18 0,000 0,05042517 0,07557588 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,05042517 0,07552954 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,05042517 0,07548326 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,05042517 0,07543704 ! glycine metabolic process GO:0006544 30 18 0,000 0,05042517 0,07539087 ! glutamine metabolic process GO:0006541 29 18 0,000 0,05042517 0,07534476 ! response to retinoic acid GO:0032526 31 18 0,000 0,05042517 0,0752987 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,05042517 0,07525271 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,05042517 0,07520676 ! DNA integration GO:0015074 32 18 0,000 0,05042517 0,07516088 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,05042517 0,07511505 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,05042517 0,07506928 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,05042517 0,07502356 ! neural crest cell migration GO:0001755 41 18 0,000 0,05042517 0,07497789 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,05042517 0,07493229 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,05042517 0,07488674 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,05042517 0,07484124 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,05042517 0,0747958 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,05042517 0,07475041 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,05042517 0,07470508 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,05042517 0,07465981 ! detection of bacterium GO:0016045 22 18 0,000 0,05042517 0,07461459 ! nerve development GO:0021675 34 18 0,000 0,05042517 0,07456942 ! defense response to virus GO:0051607 43 18 0,000 0,05042517 0,07452431 ! microspike assembly GO:0030035 46 18 0,000 0,05042517 0,07447925 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,05042517 0,07443425 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,05315153 0,07841134 ! negative regulation of defense response GO:0031348 27 19 0,000 0,05315153 0,07836402 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,05315153 0,07831675 ! neuron maturation GO:0042551 46 19 0,000 0,05315153 0,07826955 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,05315153 0,0782224 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,05315153 0,0781753 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,05315153 0,07812826 GO:0019692|deoxyribose phosphate metabolic process, ! regulation of neuronal synaptic plasticity GO:0048168 51 19 0,000 0,05315153 0,07808128 ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,05315153 0,07803436 ! inositol metabolic process GO:0006020 33 19 0,000 0,05315153 0,07798749 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,05315153 0,07794068 ! memory GO:0007613 34 19 0,000 0,05315153 0,07789393 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,05315153 0,07784723 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,05315153 0,07780058 GO:0042744|hydrogen peroxide catabolic process, ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,05315153 0,077754 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,05315153 0,07770747 ! cerebral cortex development GO:0021987 40 19 0,000 0,05315153 0,07766099 ! pigmentation during development GO:0048066 42 19 0,000 0,05315153 0,07761457 ! response to vitamin A GO:0033189 32 19 0,000 0,05315153 0,07756821 ! heme metabolic process GO:0042168 40 19 0,000 0,05315153 0,0775219 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,05315153 0,07747564 ! response to fungus GO:0009620 26 19 0,000 0,05315153 0,07742944 ! peptide cross-linking GO:0018149 39 19 0,000 0,05315153 0,0773833 ! protein export from nucleus GO:0006611 40 19 0,000 0,05315153 0,07733721 ! heart process GO:0003015 32 19 0,000 0,05315153 0,07729118 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,05315153 0,0772452 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,05315153 0,07719927 ! visual learning GO:0008542 38 19 0,000 0,05315153 0,0771534 ! cellular pigmentation GO:0033059 37 19 0,000 0,05315153 0,07710759 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,05315153 0,07706183 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,05315153 0,07701612 ! vitamin transport GO:0051180 31 19 0,000 0,05315153 0,07697047 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,05315153 0,07692487 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,05315153 0,07687932 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,05315153 0,07683383 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,05315153 0,07678839 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,05315153 0,07674301 ! cilium assembly GO:0042384 38 19 0,000 0,05315153 0,07669768 ! peptide hormone secretion GO:0030072 32 19 0,000 0,05315153 0,07665241 ! protein secretion GO:0009306 45 20 0,000 0,05587013 0,08052551 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,05587013 0,08047803 ! positive regulation of ossification GO:0045778 50 20 0,000 0,05587013 0,0804306 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,05587013 0,08038324 ! skin development GO:0043588 42 20 0,000 0,05587013 0,08033592 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,05587013 0,08028867 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,05587013 0,08024147 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,05587013 0,08019432 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,05587013 0,08014723 ! response to vitamin GO:0033273 36 20 0,000 0,05587013 0,0801002 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,05587013 0,08005322 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,05587013 0,08000629 ! bile acid metabolic process GO:0008206 34 20 0,000 0,05587013 0,07995942 ! response to alkaloid GO:0043279 38 20 0,000 0,05587013 0,07991261 ! retinoid metabolic process GO:0001523 34 20 0,000 0,05587013 0,07986585 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,05587013 0,07981914 ! apoptotic mitochondrial changes GO:0008637 42 20 0,000 0,05587013 0,07977249 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,05587013 0,0797259 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,05587013 0,07967935 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,05587013 0,07963287 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,05587013 0,07958643 ! body fluid secretion GO:0007589 33 20 0,000 0,05587013 0,07954006 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,05587013 0,07949373 ! peptide secretion GO:0002790 38 20 0,000 0,05587013 0,07944746 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,05587013 0,07940124 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,05587013 0,07935508 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,05587013 0,07930897 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,05587013 0,07926291 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,05587013 0,07921691 ! cell-cell junction organization GO:0045216 43 20 0,000 0,05587013 0,07917096 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 0,000 0,05587013 0,07912506 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,05587013 0,07907922 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,05587013 0,07903343 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,05587013 0,07898769 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,05587013 0,07894201 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,05587013 0,07889638 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,05587013 0,0788508 ! negative regulation of translation GO:0017148 32 20 0,000 0,05587013 0,07880527 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,05587013 0,0787598 ! regulation of cell killing GO:0031341 46 21 0,000 0,05858101 0,08253369 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,05858101 0,08248612 ! hormone secretion GO:0046879 39 21 0,000 0,05858101 0,0824386 ! cAMP metabolic process GO:0046058 41 21 0,000 0,05858101 0,08239114 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,05858101 0,08234373 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,05858101 0,08229638 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,05858101 0,08224909 ! ovarian follicle development GO:0001541 39 21 0,000 0,05858101 0,08220184 ! smooth muscle contraction GO:0006939 48 21 0,000 0,05858101 0,08215466 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,05858101 0,08210752 ! cell structure disassembly during apoptosis GO:0006921 32 21 0,000 0,05858101 0,08206044 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,05858101 0,08201342 ! plasma membrane fusion GO:0045026 33 21 0,000 0,05858101 0,08196644 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,05858101 0,08191953 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,05858101 0,08187266 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,05858101 0,08182585 ! sensory perception of pain GO:0019233 33 21 0,000 0,05858101 0,08177909 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,05858101 0,08173239 ! diencephalon development GO:0021536 36 21 0,000 0,05858101 0,08168574 ! collagen fibril organization GO:0030199 62 21 0,000 0,05858101 0,08163914 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,05858101 0,08159259 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,05858101 0,0815461 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,05858101 0,08149966 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,05858101 0,08145328 ! collagen catabolic process GO:0030574 29 21 0,000 0,05858101 0,08140695 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,05858101 0,08136067 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,05858101 0,08131444 ! sperm-egg recognition GO:0035036 23 21 0,000 0,05858101 0,08126826 ! actin filament-based movement GO:0030048 47 21 0,000 0,05858101 0,08122214 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,05858101 0,08117607 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,06128418 0,08487373 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,06128418 0,08482564 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,06128418 0,08477761 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,06128418 0,08472963 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,06128418 0,08468171 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,06128418 0,08463384 ! microtubule-based transport GO:0010970 59 22 0,000 0,06128418 0,08458602 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,06128418 0,08453826 ! glutamate signaling pathway GO:0007215 48 22 0,000 0,06128418 0,08449055 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,06128418 0,0844429 ! cellular response to starvation GO:0009267 37 22 0,000 0,06128418 0,0843953 ! vacuolar transport GO:0007034 41 22 0,000 0,06128418 0,08434775 ! central nervous system neuron development GO:0021954 47 22 0,000 0,06128418 0,08430026 ! fucose metabolic process GO:0006004 44 22 0,000 0,06128418 0,08425282 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,06128418 0,08420543 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,06128418 0,0841581 ! apoptotic nuclear changes GO:0030262 34 22 0,000 0,06128418 0,08411082 ! ureteric bud development GO:0001657 50 22 0,000 0,06128418 0,08406359 ! cell aging GO:0007569 48 22 0,000 0,06128418 0,08401642 ! stem cell differentiation GO:0048863 57 22 0,000 0,06128418 0,0839693 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,06128418 0,08392223 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,06128418 0,08387521 ! cytolysis GO:0019835 27 22 0,000 0,06128418 0,08382825 ! renal system process GO:0003014 42 22 0,000 0,06128418 0,08378134 ! vasodilation GO:0042311 40 22 0,000 0,06128418 0,08373448 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,06128418 0,08368768 ! G1 phase GO:0051318 44 22 0,000 0,06128418 0,08364093 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,06128418 0,08359423 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,06128418 0,08354758 ! response to glucocorticoid stimulus GO:0051384 42 22 0,000 0,06128418 0,08350098 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,06128418 0,08345444 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,06128418 0,08340794 ! sarcomere organization GO:0045214 32 22 0,000 0,06128418 0,0833615 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,06128418 0,08331511 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,06128418 0,08326877 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,06128418 0,08322249 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,06128418 0,08317625 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,06128418 0,08313007 ! gut development GO:0048565 44 22 0,000 0,06128418 0,08308394 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,06128418 0,08303786 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,06128418 0,08299183 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,06397967 0,08659409 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,06397967 0,08654614 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,06397967 0,08649824 ! glycerol metabolic process GO:0006071 40 23 0,000 0,06397967 0,0864504 ! viral genome replication GO:0019079 44 23 0,000 0,06397967 0,08640261 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,06397967 0,08635488 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,06397967 0,08630719 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,06397967 0,08625956 ! regeneration GO:0031099 42 23 0,000 0,06397967 0,08621198 ! axis specification GO:0009798 43 23 0,000 0,06397967 0,08616446 ! visual behavior GO:0007632 46 23 0,000 0,06397967 0,08611698 ! regulation of cell-matrix adhesion GO:0001952 81 23 0,000 0,06397967 0,08606956 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 51 23 0,000 0,06397967 0,08602219 ! response to ethanol GO:0045471 47 23 0,000 0,06397967 0,08597488 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,06397967 0,08592761 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,06397967 0,0858804 ! peroxisome organization GO:0007031 43 23 0,000 0,06397967 0,08583324 ! lysosome organization GO:0007040 47 23 0,000 0,06397967 0,08578613 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,06397967 0,08573907 ! vesicle targeting GO:0006903 49 23 0,000 0,06397967 0,08569207 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,06397967 0,08564511 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,06397967 0,08559821 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,06397967 0,08555136 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,06397967 0,08550456 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,06397967 0,08545781 ! DNA modification GO:0006304 36 23 0,000 0,06397967 0,08541111 ! fatty acid transport GO:0015908 47 23 0,000 0,06397967 0,08536446 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,06397967 0,08531786 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,06397967 0,08527132 ! hormone transport GO:0009914 41 23 0,000 0,06397967 0,08522482 ! cell-cell recognition GO:0009988 28 23 0,000 0,06397967 0,08517838 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,06397967 0,08513199 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,06397967 0,08508564 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,06397967 0,08503935 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,06666749 0,08856372 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,06666749 0,08851558 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 38 24 0,000 0,06666749 0,0884675 ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,06666749 0,08841947 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,06666749 0,0883715 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,06666749 0,08832357 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,06666749 0,0882757 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,06666749 0,08822788 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,06666749 0,08818011 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,06666749 0,0881324 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,06666749 0,08808473 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,06666749 0,08803712 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,06666749 0,08798956 ! response to corticosteroid stimulus GO:0031960 46 24 0,000 0,06666749 0,08794205 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,06666749 0,08789459 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,06666749 0,08784718 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,06666749 0,08779982 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,06666749 0,08775252 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,06666749 0,08770526 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,06666749 0,08765806 ! membrane depolarization GO:0051899 45 24 0,000 0,06666749 0,0876109 ! pallium development GO:0021543 56 24 0,000 0,06666749 0,0875638 ! oogenesis GO:0048477 44 24 0,000 0,06666749 0,08751675 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,06666749 0,08746975 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,06666749 0,0874228 ! platelet activation GO:0030168 41 24 0,000 0,06666749 0,0873759 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,06666749 0,08732905 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,06666749 0,08728225 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,06666749 0,0872355 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,06666749 0,0871888 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,06666749 0,08714215 ! regulation of amine transport GO:0051952 41 24 0,000 0,06666749 0,08709555 ! protein import into nucleus, translocation GO:0000060 51 25 0,000 0,06934767 0,09054856 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,06934767 0,09050019 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,06934767 0,09045187 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,06934767 0,0904036 ! leukocyte adhesion GO:0007159 55 25 0,000 0,06934767 0,09035538 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,06934767 0,09030722 ! phototransduction GO:0007602 37 25 0,000 0,06934767 0,09025911 ! keratinization GO:0031424 37 25 0,000 0,06934767 0,09021105 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 0,000 0,06934767 0,09016304 ! vacuole organization GO:0007033 49 25 0,000 0,06934767 0,09011508 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,06934767 0,09006717 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,06934767 0,09001931 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,06934767 0,08997151 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,06934767 0,08992375 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,06934767 0,08987605 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,06934767 0,08982839 ! immunoglobulin production GO:0002377 62 25 0,000 0,06934767 0,08978079 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,06934767 0,08973323 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,06934767 0,08968573 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,06934767 0,08963828 ! liver development GO:0001889 55 25 0,000 0,06934767 0,08959088 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,07202022 0,0929944 ! initiation of viral infection GO:0019059 60 26 0,000 0,07202022 0,09294527 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,07202022 0,0928962 ! molting cycle process GO:0022404 52 26 0,000 0,07202022 0,09284718 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,07202022 0,09279821 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,07202022 0,09274929 GO:0006479|protein amino acid methylation, ! microtubule organizing center organization GO:0031023 42 26 0,000 0,07202022 0,09270042 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,07202022 0,09265161 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,07202022 0,09260284 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,07202022 0,09255413 ! digestive system process GO:0022600 49 26 0,000 0,07202022 0,09250547 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,07202022 0,09245686 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,07202022 0,0924083 ! osteoblast differentiation GO:0001649 63 26 0,000 0,07202022 0,09235979 ! neural crest cell development GO:0014032 59 26 0,000 0,07202022 0,09231133 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,07202022 0,09226293 ! negative regulation of cell development GO:0010721 83 26 0,000 0,07202022 0,09221457 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,07202022 0,09216627 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,07202022 0,09211801 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,07202022 0,09206981 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,07202022 0,09202165 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,07202022 0,09197355 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,07202022 0,0919255 ! positive regulation of nuclear division GO:0051785 41 26 0,000 0,07202022 0,09187749 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,07202022 0,09182954 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,07202022 0,09178164 ! blastocyst development GO:0001824 50 26 0,000 0,07202022 0,09173379 ! telomere organization GO:0032200 46 26 0,000 0,07202022 0,09168598 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,07202022 0,09163823 ! neural tube closure GO:0001843 58 26 0,000 0,07202022 0,09159053 GO:0060606|tube closure, ! alditol metabolic process GO:0019400 44 26 0,000 0,07202022 0,09154287 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,07202022 0,09149527 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,07202022 0,09144771 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,07468518 0,09478228 ! embryonic pattern specification GO:0009880 49 27 0,000 0,07468518 0,09473307 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,07468518 0,09468391 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,07468518 0,0946348 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,07468518 0,09458574 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,07468518 0,09453673 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,07468518 0,09448777 ! iron ion transport GO:0006826 65 27 0,000 0,07468518 0,09443887 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,07468518 0,09439001 ! superoxide metabolic process GO:0006801 41 27 0,000 0,07468518 0,09434121 ! tube lumen formation GO:0035148 59 27 0,000 0,07468518 0,09429245 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,07468518 0,09424375 ! mitochondrial membrane organization GO:0007006 60 27 0,000 0,07468518 0,09419509 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,07468518 0,09414649 ! response to starvation GO:0042594 47 27 0,000 0,07468518 0,09409793 ! response to toxin GO:0009636 49 27 0,000 0,07468518 0,09404943 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,07468518 0,09400097 ! regulation of chromosome organization GO:0033044 49 27 0,000 0,07468518 0,09395257 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,07468518 0,09390422 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,07468518 0,09385591 ! leukocyte proliferation GO:0070661 59 27 0,000 0,07468518 0,09380766 GO:0032943|mononuclear cell proliferation, ! neuron fate commitment GO:0048663 52 28 0,000 0,07734256 0,09709551 ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,07734256 0,09704564 ! protein amino acid acylation GO:0043543 59 28 0,000 0,07734256 0,09699583 ! vesicle docking GO:0048278 55 28 0,000 0,07734256 0,09694606 ! fat cell differentiation GO:0045444 57 28 0,000 0,07734256 0,09689634 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,07734256 0,09684668 ! sperm motility GO:0030317 37 28 0,000 0,07734256 0,09679706 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,07734256 0,0967475 ! base-excision repair GO:0006284 41 28 0,000 0,07734256 0,09669799 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,07734256 0,09664853 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,07734256 0,09659911 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,07734256 0,09654975 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,07734256 0,09650044 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,07734256 0,09645118 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,07734256 0,09640197 ! glutathione metabolic process GO:0006749 42 28 0,000 0,07734256 0,09635281 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,07734256 0,0963037 ! lipid oxidation GO:0034440 48 28 0,000 0,07734256 0,09625464 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,07734256 0,09620564 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,07734256 0,09615668 ! translational initiation GO:0006413 66 29 0,000 0,07999238 0,0994005 ! cellular iron ion homeostasis GO:0006879 57 29 0,000 0,07999238 0,09934997 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,07999238 0,09929948 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,07999238 0,09924905 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,07999238 0,09919867 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,07999238 0,09914834 ! primary neural tube formation GO:0014020 61 29 0,000 0,07999238 0,09909806 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,07999238 0,09904784 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,07999238 0,09899766 ! response to organic cyclic substance GO:0014070 58 29 0,000 0,07999238 0,09894753 ! somitogenesis GO:0001756 52 29 0,000 0,07999238 0,09889746 ! synaptogenesis GO:0007416 46 29 0,000 0,07999238 0,09884744 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,07999238 0,09879746 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,07999238 0,09874754 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,07999238 0,09869767 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,07999238 0,09864785 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,08263466 0,10185494 ! phenol metabolic process GO:0018958 56 30 0,000 0,08263466 0,10180357 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,08263466 0,10175226 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,08263466 0,101701 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,08263466 0,10164979 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,08263466 0,10159863 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,08263466 0,10154753 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,08263466 0,10149647 ! acute-phase response GO:0006953 50 30 0,000 0,08263466 0,10144547 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,08263466 0,10139452 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,08263466 0,10134362 ! myofibril assembly GO:0030239 50 30 0,000 0,08263466 0,10129277 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,08263466 0,10124197 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,08263466 0,10119122 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,08263466 0,10114052 ! cell fate determination GO:0001709 64 30 0,000 0,08263466 0,10108988 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,08263466 0,10103928 ! phospholipid transport GO:0015914 65 30 0,000 0,08263466 0,10098874 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,08263466 0,10093824 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,08263466 0,1008878 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,08263466 0,10083741 ! tissue homeostasis GO:0001894 50 30 0,000 0,08263466 0,10078706 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 0,000 0,08263466 0,10073677 ! regulation of coagulation GO:0050818 52 30 0,000 0,08263466 0,10068653 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,08526944 0,10384508 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,08526944 0,10379334 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,08526944 0,10374165 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,08526944 0,10369001 ! cell junction assembly GO:0034329 85 31 0,000 0,08526944 0,10363842 ! regulation of innate immune response GO:0045088 57 31 0,000 0,08526944 0,10358689 ! ovulation cycle process GO:0022602 55 31 0,000 0,08526944 0,1035354 ! peptide transport GO:0015833 60 31 0,000 0,08526944 0,10348397 ! male gonad development GO:0008584 56 31 0,000 0,08526944 0,10343259 ! iron ion homeostasis GO:0055072 60 31 0,000 0,08526944 0,10338126 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,08526944 0,10332998 ! detection of light stimulus GO:0009583 44 31 0,000 0,08526944 0,10327875 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,08526944 0,10322757 ! natural killer cell activation GO:0030101 50 31 0,000 0,08526944 0,10317644 ! cofactor catabolic process GO:0051187 54 31 0,000 0,08526944 0,10312536 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,08526944 0,10307434 ! eye morphogenesis GO:0048592 65 31 0,000 0,08526944 0,10302336 ! response to heat GO:0009408 54 31 0,000 0,08526944 0,10297243 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,08526944 0,10292156 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,08789671 0,10604033 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,08789671 0,10598799 ! collagen metabolic process GO:0032963 49 32 0,000 0,08789671 0,1059357 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,08789671 0,10588347 ! spindle organization GO:0007051 50 32 0,000 0,08789671 0,10583128 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,08789671 0,10577915 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,08789671 0,10572707 ! metanephros development GO:0001656 81 32 0,000 0,08789671 0,10567504 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,08789671 0,10562306 ! muscle cell development GO:0055001 52 32 0,000 0,08789671 0,10557113 ! mesoderm formation GO:0001707 73 32 0,000 0,08789671 0,10551925 ! ovulation cycle GO:0042698 57 32 0,000 0,08789671 0,10546742 ! BMP signaling pathway GO:0030509 71 32 0,000 0,08789671 0,10541565 ! hindbrain development GO:0030902 65 32 0,000 0,08789671 0,10536392 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,08789671 0,10531225 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,08789671 0,10526062 ! gene silencing GO:0016458 71 32 0,000 0,08789671 0,10520905 ! regulation of pH GO:0006885 56 33 0,000 0,09051652 0,1082918 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,09051652 0,10823879 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,09051652 0,10818584 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,09051652 0,10813294 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,09051652 0,10808009 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,09051652 0,10802729 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,09051652 0,10797454 ! response to ionizing radiation GO:0010212 74 33 0,000 0,09051652 0,10792184 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,09051652 0,1078692 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,09051652 0,1078166 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,09051652 0,10776406 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,09051652 0,10771157 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,09051652 0,10765913 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,09312887 0,11071233 ! glial cell differentiation GO:0010001 67 34 0,000 0,09312887 0,11065848 ! post-embryonic development GO:0009791 76 34 0,000 0,09312887 0,11060469 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,09312887 0,11055094 ! cholesterol transport GO:0030301 62 34 0,000 0,09312887 0,11049725 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,09312887 0,11044361 ! spliceosome assembly GO:0000245 75 34 0,000 0,09312887 0,11039002 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,09312887 0,11033649 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,09312887 0,110283 ! formation of primary germ layer GO:0001704 76 34 0,000 0,09312887 0,11022957 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,09312887 0,11017619 ! adult locomotory behavior GO:0008344 62 34 0,000 0,09312887 0,11012286 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,0957338 0,11314836 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,0957338 0,11309365 ! negative regulation of secretion GO:0051048 68 35 0,000 0,0957338 0,11303899 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,0957338 0,11298438 ! regulation of synaptic plasticity GO:0048167 78 35 0,000 0,0957338 0,11292982 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,0957338 0,11287532 ! membrane docking GO:0022406 69 35 0,000 0,0957338 0,11282087 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,0957338 0,11276647 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,0957338 0,11271213 ! regulation of striated muscle tissue development GO:0016202 81 35 0,000 0,0957338 0,11265784 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 0,000 0,0957338 0,1126036 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,0957338 0,11254941 ! ceramide metabolic process GO:0006672 72 35 0,000 0,0957338 0,11249527 ! telencephalon development GO:0021537 81 35 0,000 0,0957338 0,11244119 ! sterol transport GO:0015918 63 35 0,000 0,0957338 0,11238715 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,0957338 0,11233317 ! placenta development GO:0001890 53 35 0,000 0,0957338 0,11227925 ! vesicle localization GO:0051648 70 35 0,000 0,0957338 0,11222537 ! regulation of muscle development GO:0048634 82 36 0,000 0,09833131 0,11521506 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,09833131 0,11515983 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,09833131 0,11510465 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,09833131 0,11504952 ! positive regulation of cell development GO:0010720 85 36 0,000 0,09833131 0,11499445 ! protein targeting to membrane GO:0006612 75 36 0,000 0,09833131 0,11493942 ! regulation of proteolysis GO:0030162 77 36 0,000 0,09833131 0,11488446 ! negative regulation of hydrolase activity GO:0051346 66 36 0,000 0,09833131 0,11482954 ! aerobic respiration GO:0009060 56 36 0,000 0,09833131 0,11477468 ! cytokine production GO:0001816 68 36 0,000 0,09833131 0,11471986 ! embryonic organ development GO:0048568 67 36 0,000 0,09833131 0,11466511 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,09833131 0,1146104 ! negative regulation of cell adhesion GO:0007162 94 37 0,000 0,10092144 0,11757324 ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,10092144 0,11751719 ! odontogenesis GO:0042476 74 37 0,000 0,10092144 0,11746121 ! actomyosin structure organization GO:0031032 68 37 0,000 0,10092144 0,11740527 ! cell junction organization GO:0034330 96 37 0,000 0,10092144 0,11734939 ! female gonad development GO:0008585 71 37 0,000 0,10092144 0,11729357 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,10092144 0,11723779 ! androgen receptor signaling pathway GO:0030521 81 37 0,000 0,10092144 0,11718207 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,1035042 0,12012387 ! meiosis I GO:0007127 74 38 0,000 0,1035042 0,12006683 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,1035042 0,12000985 ! organic anion transport GO:0015711 82 38 0,000 0,1035042 0,11995292 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,1035042 0,11989604 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,1035042 0,11983922 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,1035042 0,11978245 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,1035042 0,11972574 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,1035042 0,11966907 ! spermatid development GO:0007286 69 38 0,000 0,1035042 0,11961247 ! pigment metabolic process GO:0042440 87 38 0,000 0,1035042 0,11955591 ! neural tube formation GO:0001841 79 38 0,000 0,1035042 0,11949941 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,10607961 0,12241497 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,10607961 0,12235717 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,10607961 0,12229943 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,10607961 0,12224174 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,10607961 0,1221841 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,10607961 0,12212652 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,10607961 0,122069 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,10607961 0,12201153 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,10864769 0,1249065 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,10864769 0,12484775 ! learning GO:0007612 82 40 0,000 0,10864769 0,12478905 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,10864769 0,12473041 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 73 40 0,000 0,10864769 0,12467183 ! lipid homeostasis GO:0055088 75 40 0,000 0,10864769 0,1246133 ! mismatch repair GO:0006298 58 40 0,000 0,10864769 0,12455482 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,10864769 0,1244964 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,10864769 0,12443803 ! RNA export from nucleus GO:0006405 61 41 0,000 0,11120847 0,1273113 ! mRNA catabolic process GO:0006402 79 41 0,000 0,11120847 0,12725166 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,11120847 0,12719209 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,11120847 0,12713257 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,11120847 0,12707311 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 0,000 0,11120847 0,1270137 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,11120847 0,12695435 ! gliogenesis GO:0042063 91 41 0,000 0,11120847 0,12689505 ! feeding behavior GO:0007631 69 41 0,000 0,11120847 0,12683581 ! multicellular organismal metabolic process GO:0044236 64 41 0,000 0,11120847 0,12677662 ! mesenchymal cell development GO:0014031 94 41 0,000 0,11120847 0,12671749 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,11120847 0,12665842 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,11120847 0,1265994 GO:0015986|ATP synthesis coupled proton transport, ! spermatid differentiation GO:0048515 73 41 0,000 0,11120847 0,12654043 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,11120847 0,12648152 ! RNA modification GO:0009451 64 41 0,000 0,11120847 0,12642266 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,11376197 0,12926535 ! ear morphogenesis GO:0042471 64 42 0,000 0,11376197 0,12920525 ! organic ether metabolic process GO:0018904 59 42 0,000 0,11376197 0,12914521 ! T cell differentiation GO:0030217 93 42 0,000 0,11376197 0,12908523 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,11376197 0,1290253 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,11376197 0,12896543 ! regulation of protein secretion GO:0050708 77 42 0,000 0,11376197 0,12890561 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,11376197 0,12884585 ! cytokinesis GO:0000910 84 42 0,000 0,11376197 0,12878614 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,11376197 0,12872649 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,1163082 0,13154673 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,1163082 0,13148586 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,1163082 0,13142504 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,1163082 0,13136428 ! regulation of tube size GO:0035150 76 43 0,000 0,1163082 0,13130357 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,1163082 0,13124293 ! glucose transport GO:0015758 66 43 0,000 0,1163082 0,13118233 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,1163082 0,1311218 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,1163082 0,13106132 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,1163082 0,13100089 ! development of primary male sexual characteristics GO:0046546 80 43 0,000 0,1163082 0,13094052 ! segmentation GO:0035282 78 43 0,000 0,1163082 0,13088021 ! ion transmembrane transport GO:0034220 79 43 0,000 0,1163082 0,13081995 ! neuron migration GO:0001764 85 43 0,000 0,1163082 0,13075975 ! regulation of myeloid cell differentiation GO:0045637 105 43 0,000 0,1163082 0,1306996 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,11884719 0,13349135 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,11884719 0,13343 ! hexose transport GO:0008645 68 44 0,000 0,11884719 0,13336871 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,11884719 0,13330747 ! striated muscle contraction GO:0006941 85 44 0,000 0,11884719 0,1332463 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,11884719 0,13318517 ! double-strand break repair GO:0006302 85 44 0,000 0,11884719 0,13312411 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,12137895 0,1358977 ! branching morphogenesis of a tube GO:0048754 102 45 0,000 0,12137895 0,13583544 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,12137895 0,13577325 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,12137895 0,13571111 ! biopolymer methylation GO:0043414 91 45 0,000 0,12137895 0,13564903 ! B cell differentiation GO:0030183 124 45 0,000 0,12137895 0,135587 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,12137895 0,13552503 ! female gamete generation GO:0007292 71 45 0,000 0,12137895 0,13546312 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,12137895 0,13540127 ! polyol metabolic process GO:0019751 77 45 0,000 0,12137895 0,13533947 ! developmental growth GO:0048589 88 45 0,000 0,12137895 0,13527773 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,12390351 0,1380284 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,12390351 0,13796549 ! glycolysis GO:0006096 71 46 0,000 0,12390351 0,13790263 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,12390351 0,13783983 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,12390351 0,13777709 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,12390351 0,13771441 ! pigmentation GO:0043473 103 46 0,000 0,12390351 0,13765178 ! neural tube development GO:0021915 91 47 0,000 0,12642089 0,14038465 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,1289311 0,14310708 ! mitochondrial transport GO:0006839 94 48 0,000 0,1289311 0,14304209 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,1289311 0,14297716 ! cellular component disassembly GO:0022411 89 48 0,000 0,1289311 0,14291229 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,1289311 0,14284747 ! male sex differentiation GO:0046661 93 48 0,000 0,1289311 0,14278272 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,1289311 0,14271802 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,1289311 0,14265339 ! JAK-STAT cascade GO:0007259 82 48 0,000 0,1289311 0,14258881 ! methylation GO:0032259 97 48 0,000 0,1289311 0,14252429 ! response to calcium ion GO:0051592 94 49 0,000 0,13143417 0,14522555 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,13143417 0,14515989 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,13143417 0,1450943 ! protein homooligomerization GO:0051260 84 49 0,000 0,13143417 0,14502876 ! regulation of ion transport GO:0043269 86 50 0,000 0,13393012 0,14771616 ! endocrine system development GO:0035270 109 50 0,000 0,13393012 0,1476495 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,13393012 0,1475829 ! activation of caspase activity GO:0006919 95 50 0,000 0,13393012 0,14751636 ! regulation of ossification GO:0030278 123 50 0,000 0,13393012 0,14744988 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,13393012 0,14738346 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,13393012 0,1473171 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,13393012 0,1472508 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,13393012 0,14718456 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,13393012 0,14711838 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,13641897 0,14978496 ! viral infectious cycle GO:0019058 104 51 0,000 0,13641897 0,14971767 ! response to temperature stimulus GO:0009266 84 51 0,000 0,13641897 0,14965044 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,13641897 0,14958328 ! positive regulation of binding GO:0051099 88 52 0,000 0,13890073 0,1522362 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,13890073 0,15216793 ! Notch signaling pathway GO:0007219 111 52 0,000 0,13890073 0,15209973 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,13890073 0,15203158 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,13890073 0,1519635 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,13890073 0,15189547 ! excretion GO:0007588 87 52 0,000 0,13890073 0,15182751 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,13890073 0,15175961 ! histone modification GO:0016570 104 52 0,000 0,13890073 0,15169177 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,13890073 0,15162399 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,13890073 0,15155627 ! morphogenesis of a branching structure GO:0001763 116 52 0,000 0,13890073 0,15148861 ! amino acid activation GO:0043038 98 52 0,000 0,13890073 0,15142101 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,14137543 0,15405004 ! inner ear development GO:0048839 89 53 0,000 0,14137543 0,15398136 ! chromatin remodeling GO:0006338 122 53 0,000 0,14137543 0,15391274 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 0,000 0,14137543 0,15384418 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,14137543 0,15377568 ! vesicle organization GO:0016050 127 53 0,000 0,14137543 0,15370725 ! regulation of neuron apoptosis GO:0043523 117 53 0,000 0,14137543 0,15363887 ! regulation of translational initiation GO:0006446 87 54 0,000 0,14384309 0,15625108 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,14384309 0,15618164 ! neuromuscular process GO:0050905 107 54 0,000 0,14384309 0,15611225 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,14384309 0,15604293 ! membrane fusion GO:0006944 122 54 0,000 0,14384309 0,15597367 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,14384309 0,15590447 ! covalent chromatin modification GO:0016569 115 54 0,000 0,14384309 0,15583533 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,14384309 0,15576626 ! epithelial tube morphogenesis GO:0060562 114 54 0,000 0,14384309 0,15569724 ! RNA catabolic process GO:0006401 103 55 0,000 0,14630373 0,15829053 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,14630373 0,15822046 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,14630373 0,15815045 ! cell recognition GO:0008037 98 55 0,000 0,14630373 0,1580805 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,14630373 0,15801062 ! cell maturation GO:0048469 107 55 0,000 0,14630373 0,15794079 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,14630373 0,15787103 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,14630373 0,15780133 ! glucose catabolic process GO:0006007 88 56 0,000 0,14875737 0,16037698 ! RNA elongation GO:0006354 90 56 0,000 0,14875737 0,16030624 ! chloride transport GO:0006821 102 57 0,000 0,15120402 0,16287099 ! positive regulation of caspase activity GO:0043280 108 57 0,000 0,15120402 0,16279921 GO:0010952|positive regulation of peptidase activity, ! nucleotide-excision repair GO:0006289 91 57 0,000 0,15120402 0,16272749 ! regulation of actin filament length GO:0030832 118 58 0,000 0,1536437 0,1652803 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,1536437 0,16520756 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,1536437 0,16513487 ! aging GO:0007568 112 58 0,000 0,1536437 0,16506226 ! gastrulation GO:0007369 122 58 0,000 0,1536437 0,1649897 ! positive regulation of organelle organization GO:0010638 108 58 0,000 0,1536437 0,16491721 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,1536437 0,16484478 ! nuclear export GO:0051168 110 59 0,000 0,15607645 0,16738137 ! establishment of organelle localization GO:0051656 122 59 0,000 0,15607645 0,16730793 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,15850227 0,16983379 ! DNA catabolic process GO:0006308 94 60 0,000 0,15850227 0,16975933 ! regulation of endocytosis GO:0030100 104 60 0,000 0,15850227 0,16968494 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,15850227 0,16961062 ! adult behavior GO:0030534 104 60 0,000 0,15850227 0,16953636 ! kidney development GO:0001822 133 60 0,000 0,15850227 0,16946216 ! positive regulation of secretion GO:0051047 110 61 0,000 0,16092118 0,17197307 ! regulation of cellular component size GO:0032535 125 61 0,000 0,16092118 0,17189788 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,16092118 0,17182275 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,16092118 0,17174768 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,16092118 0,17167268 ! camera-type eye development GO:0043010 126 61 0,000 0,16092118 0,17159775 ! proton transport GO:0015992 117 61 0,000 0,16092118 0,17152288 ! DNA damage response, signal transduction GO:0042770 136 62 0,000 0,16333321 0,1740179 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,16333321 0,17394204 ! tRNA processing GO:0008033 102 62 0,000 0,16333321 0,17386625 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,16573837 0,17634967 ! mesoderm development GO:0007498 128 63 0,000 0,16573837 0,1762729 ! skeletal system morphogenesis GO:0048705 118 63 0,000 0,16573837 0,17619619 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,16573837 0,17611955 ! hydrogen transport GO:0006818 121 64 0,000 0,16813669 0,17859041 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,16813669 0,17851279 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,16813669 0,17843525 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,17052818 0,18089464 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,17052818 0,18081612 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,17052818 0,18073768 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,17052818 0,1806593 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,17052818 0,18058099 ! ear development GO:0043583 114 66 0,000 0,17291286 0,18302692 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,17291286 0,18294765 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,17291286 0,18286845 ! gonad development GO:0008406 115 66 0,000 0,17291286 0,18278932 ! steroid hormone receptor signaling pathway GO:0030518 146 66 0,000 0,17291286 0,18271026 ! negative regulation of cell growth GO:0030308 142 67 0,000 0,17529076 0,18514281 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,17529076 0,1850628 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,17529076 0,18498286 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,17529076 0,18490299 ! secondary metabolic process GO:0019748 125 67 0,000 0,17529076 0,18482318 ! myeloid cell differentiation GO:0030099 126 67 0,000 0,17529076 0,18474345 ! hexose catabolic process GO:0019320 113 68 0,000 0,17766188 0,1871617 ! extracellular matrix organization GO:0030198 146 68 0,000 0,17766188 0,18708102 ! negative regulation of ligase activity GO:0051352 116 68 0,000 0,17766188 0,18700042 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 0,000 0,17766188 0,18691988 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,17766188 0,18683942 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 0,000 0,17766188 0,18675902 ! cell projection assembly GO:0030031 138 68 0,000 0,17766188 0,1866787 ! negative regulation of cell size GO:0045792 144 69 0,000 0,18002625 0,18908174 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,18002625 0,18900049 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 0,000 0,18002625 0,1889193 ! urogenital system development GO:0001655 149 69 0,000 0,18002625 0,18883819 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,18002625 0,18875714 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,18002625 0,18867616 ! developmental maturation GO:0021700 128 69 0,000 0,18002625 0,18859525 ! single fertilization GO:0007338 83 69 0,000 0,18002625 0,18851442 ! cell redox homeostasis GO:0045454 114 70 0,000 0,18238389 0,19090139 ! germ cell development GO:0007281 133 70 0,000 0,18238389 0,19081964 ! activation of immune response GO:0002253 120 70 0,000 0,18238389 0,19073795 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,18238389 0,19065633 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,18473482 0,1930313 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 0,000 0,18473482 0,19294877 ! appendage morphogenesis GO:0035107 150 72 0,000 0,18707906 0,19531373 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,18707906 0,1952303 ! B cell activation GO:0042113 179 72 0,000 0,18707906 0,19514694 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 0,000 0,18707906 0,19506365 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 0,000 0,18707906 0,19498043 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,18707906 0,19489729 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,18707906 0,19481421 ! appendage development GO:0048736 151 73 0,000 0,18941662 0,19716438 GO:0060173|limb development, ! humoral immune response GO:0006959 115 73 0,000 0,18941662 0,19708041 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,18941662 0,19699651 ! regulation of immune effector process GO:0002697 156 73 0,000 0,18941662 0,19691268 ! acute inflammatory response GO:0002526 118 74 0,000 0,19174752 0,19925104 ! amino acid transport GO:0006865 148 74 0,000 0,19174752 0,19916632 ! regulation of caspase activity GO:0043281 136 74 0,000 0,19174752 0,19908168 ! organelle localization GO:0051640 155 74 0,000 0,19174752 0,19899711 ! transition metal ion transport GO:0000041 143 75 0,000 0,19407179 0,20132373 ! reproductive structure development GO:0048608 131 75 0,000 0,19407179 0,20123828 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,19407179 0,2011529 ! eye development GO:0001654 155 75 0,000 0,19407179 0,20106759 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,19638944 0,20338253 ! learning or memory GO:0007611 161 76 0,000 0,19638944 0,20329635 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,19638944 0,20321025 ! regulation of blood pressure GO:0008217 134 76 0,000 0,19638944 0,20312421 ! lymphocyte differentiation GO:0030098 193 76 0,000 0,19638944 0,20303825 ! amine catabolic process GO:0009310 136 77 0,000 0,19870049 0,20534065 ! neurotransmitter transport GO:0006836 142 77 0,000 0,19870049 0,20525382 ! regulation of endopeptidase activity GO:0052548 141 77 0,000 0,19870049 0,20516707 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,19870049 0,20508039 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,19870049 0,20499379 ! positive regulation of ligase activity GO:0051351 130 77 0,000 0,19870049 0,20490726 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,19870049 0,2048208 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,20100495 0,20710886 ! antigen processing and presentation GO:0019882 117 78 0,000 0,20100495 0,20702154 ! fertilization GO:0009566 99 78 0,000 0,20100495 0,2069343 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,20100495 0,20684714 ! blood coagulation GO:0007596 151 79 0,000 0,20330286 0,20912374 GO:0050817|coagulation, ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,20330286 0,20903573 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 0,000 0,20330286 0,20894778 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,20330286 0,20885992 ! response to steroid hormone stimulus GO:0048545 147 79 0,000 0,20330286 0,20877212 ! regulation of synaptic transmission GO:0050804 159 79 0,000 0,20330286 0,2086844 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,20559422 0,21094779 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,20559422 0,21085923 ! development of primary sexual characteristics GO:0045137 143 80 0,000 0,20559422 0,21077074 ! meiosis GO:0007126 143 81 0,000 0,20787905 0,21302371 GO:0051327|M phase of meiotic cell cycle, ! muscle cell differentiation GO:0042692 178 81 0,000 0,20787905 0,21293439 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,20787905 0,21284515 ! regulation of peptidase activity GO:0052547 150 82 0,000 0,21015738 0,21508776 ! protein import into nucleus GO:0006606 174 82 0,000 0,21015738 0,21499769 ! meiotic cell cycle GO:0051321 144 82 0,000 0,21015738 0,2149077 ! exocytosis GO:0006887 153 83 0,000 0,21242922 0,21713999 ! response to drug GO:0042493 149 83 0,000 0,21242922 0,21704918 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,21242922 0,21695844 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,21242922 0,21686778 ! nuclear import GO:0051170 177 83 0,000 0,21242922 0,21677719 ! inorganic anion transport GO:0015698 156 83 0,000 0,21242922 0,21668667 ! response to metal ion GO:0010038 158 84 0,000 0,21469459 0,21890604 ! T cell activation GO:0042110 189 84 0,000 0,21469459 0,21881472 ! response to nutrient GO:0007584 135 84 0,000 0,21469459 0,21872347 ! digestion GO:0007586 130 84 0,000 0,21469459 0,2186323 ! regulation of ligase activity GO:0051340 147 84 0,000 0,21469459 0,2185412 ! hemostasis GO:0007599 165 85 0,000 0,2169535 0,22074861 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,2169535 0,22065671 ! negative regulation of growth GO:0045926 168 85 0,000 0,2169535 0,22056488 ! regulation of neuron differentiation GO:0045664 187 85 0,000 0,2169535 0,22047313 ! regulation of transmission of nerve impulse GO:0051969 167 85 0,000 0,2169535 0,22038146 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,21920599 0,22257698 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,22145205 0,22476417 ! mitochondrion organization GO:0007005 159 87 0,000 0,22145205 0,22467083 ! alcohol catabolic process GO:0046164 142 87 0,000 0,22145205 0,22457757 ! nucleosome assembly GO:0006334 126 87 0,000 0,22145205 0,22448438 ! cellular respiration GO:0045333 143 88 0,000 0,22369172 0,22666067 ! amine biosynthetic process GO:0009309 146 88 0,000 0,22369172 0,2265667 ! sensory perception of smell GO:0007608 117 88 0,000 0,22369172 0,2264728 ! chromatin assembly GO:0031497 128 88 0,000 0,22369172 0,22637899 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,22369172 0,22628525 ! tube morphogenesis GO:0035239 194 89 0,000 0,22592501 0,22844983 ! cellular defense response GO:0006968 123 89 0,000 0,22592501 0,22835531 ! protein localization in nucleus GO:0034504 192 89 0,000 0,22592501 0,22826087 ! regulation of neurological system process GO:0031644 175 89 0,000 0,22592501 0,22816651 ! response to inorganic substance GO:0010035 173 90 0,000 0,22815193 0,23032032 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,22815193 0,23022518 ! response to unfolded protein GO:0006986 139 90 0,000 0,22815193 0,23013013 ! defense response to bacterium GO:0042742 112 91 0,000 0,23037251 0,23227406 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,23258677 0,23440985 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 0,000 0,23479472 0,23653752 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 0,000 0,23479472 0,23644002 ! vitamin metabolic process GO:0006766 153 93 0,000 0,23479472 0,2363426 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,23699637 0,23846052 ! female pregnancy GO:0007565 166 94 0,000 0,23699637 0,23836235 ! sterol metabolic process GO:0016125 166 94 0,000 0,23699637 0,23826426 ! nucleosome organization GO:0034728 143 95 0,000 0,23919176 0,24037247 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,23919176 0,24027363 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,23919176 0,24017487 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,23919176 0,2400762 ! sex differentiation GO:0007548 171 96 0,000 0,24138089 0,24217393 ! response to protein stimulus GO:0051789 158 96 0,000 0,24138089 0,24207451 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,24356378 0,24416344 ! transcription initiation GO:0006352 171 97 0,000 0,24356378 0,24406329 ! leukocyte differentiation GO:0002521 232 98 0,000 0,24574045 0,24614347 ! forebrain development GO:0030900 210 98 0,000 0,24574045 0,24604259 ! mRNA transport GO:0051028 185 100 0,000 0,25007521 0,2502801 ! positive regulation of immune response GO:0050778 175 100 0,000 0,25007521 0,25017761 ! hormone metabolic process GO:0042445 171 100 0,000 0,25007521 0,25007521