pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6434-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of MAP kinase activity GO:0043405 67 66 8,000 2,082E-09 3,836E-06 ! positive regulation of MAP kinase activity GO:0043406 50 49 7,000 4,001E-09 3,687E-06 ! positive regulation of protein kinase activity GO:0045860 89 86 8,000 2,284E-08 1,403E-05 ! positive regulation of transferase activity GO:0051347 91 88 8,000 2,803E-08 1,292E-05 GO:0033674|positive regulation of kinase activity, ! response to radiation GO:0009314 70 68 7,000 5,824E-08 2,147E-05 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 3,000 5,835E-08 1,792E-05 ! regulation of mitotic cell cycle GO:0007346 72 69 7,000 6,547E-08 1,724E-05 ! regulation of cell migration GO:0030334 71 71 7,000 8,227E-08 1,895E-05 ! response to UV GO:0009411 29 29 5,000 9,088E-08 1,861E-05 ! response to light stimulus GO:0009416 53 52 6,000 1,622E-07 2,989E-05 ! regulation of locomotion GO:0040012 79 79 7,000 1,919E-07 3,215E-05 ! regulation of cell motion GO:0051270 79 79 7,000 1,919E-07 2,947E-05 ! negative regulation of blood coagulation GO:0030195 9 8 3,000 2,69E-07 3,814E-05 ! release of cytochrome c from mitochondria GO:0001836 9 8 3,000 2,69E-07 3,542E-05 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 5,000 2,991E-07 3,675E-05 ! peptidyl-amino acid modification GO:0018193 61 59 6,000 3,958E-07 4,559E-05 ! apoptotic mitochondrial changes GO:0008637 11 10 3,000 7,974E-07 8,644E-05 ! negative regulation of coagulation GO:0050819 11 10 3,000 7,974E-07 8,164E-05 ! positive regulation of growth GO:0045927 23 23 4,000 8,963E-07 8,694E-05 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 3,000 1,245E-06 1,148E-04 ! gland development GO:0048732 51 49 5,000 2,361E-06 2,072E-04 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 3,000 2,666E-06 2,233E-04 ! tube development GO:0035295 83 81 6,000 3,515E-06 2,816E-04 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 3,000 3,71E-06 2,849E-04 ! regulation of blood coagulation GO:0030193 15 14 3,000 3,71E-06 2,735E-04 ! response to hypoxia GO:0001666 53 53 5,000 3,78E-06 2,679E-04 ! response to oxygen levels GO:0070482 55 54 5,000 4,226E-06 2,885E-04 ! negative regulation of multicellular organismal process GO:0051241 55 54 5,000 4,226E-06 2,782E-04 ! prostate gland development GO:0030850 5 5 2,000 5,05E-06 3,21E-04 ! T cell lineage commitment GO:0002360 5 5 2,000 5,05E-06 3,103E-04 ! negative regulation of neuroblast proliferation GO:0007406 5 5 2,000 5,05E-06 3,003E-04 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 6,000 5,264E-06 3,032E-04 ! heart development GO:0007507 90 87 6,000 5,688E-06 3,177E-04 ! regulation of neuron apoptosis GO:0043523 34 33 4,000 5,942E-06 3,221E-04 ! regulation of coagulation GO:0050818 17 16 3,000 6,664E-06 3,509E-04 ! regulation of angiogenesis GO:0045765 35 34 4,000 6,923E-06 3,544E-04 ! pigmentation GO:0043473 17 17 3,000 8,661E-06 4,314E-04 ! positive regulation of cell migration GO:0030335 36 36 4,000 9,265E-06 4,493E-04 ! focal adhesion formation GO:0048041 7 6 2,000 1,004E-05 4,746E-04 ! meiosis GO:0007126 37 37 4,000 1,065E-05 4,905E-04 GO:0051327|M phase of meiotic cell cycle, ! lung development GO:0030324 38 37 4,000 1,065E-05 4,786E-04 ! DNA damage response, signal transduction GO:0042770 37 37 4,000 1,065E-05 4,672E-04 ! meiosis I GO:0007127 18 18 3,000 1,107E-05 4,744E-04 ! cell-matrix adhesion GO:0007160 39 38 4,000 1,218E-05 5,103E-04 ! urogenital system development GO:0001655 38 38 4,000 1,218E-05 4,99E-04 ! meiotic cell cycle GO:0051321 38 38 4,000 1,218E-05 4,881E-04 ! respiratory tube development GO:0030323 40 39 4,000 1,389E-05 5,446E-04 ! respiratory system development GO:0060541 40 39 4,000 1,389E-05 5,333E-04 ! positive regulation of cell motion GO:0051272 39 39 4,000 1,389E-05 5,224E-04 ! DNA damage checkpoint GO:0000077 19 19 3,000 1,394E-05 5,137E-04 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 3,000 1,394E-05 5,036E-04 ! regulation of cell size GO:0008361 68 68 5,000 1,641E-05 5,816E-04 ! peptidyl-tyrosine modification GO:0018212 21 20 3,000 1,731E-05 6,021E-04 ! UV protection GO:0009650 7 7 2,000 1,747E-05 5,964E-04 ! induction of an organ GO:0001759 7 7 2,000 1,747E-05 5,855E-04 ! autonomic nervous system development GO:0048483 7 7 2,000 1,747E-05 5,751E-04 ! response to gamma radiation GO:0010332 8 7 2,000 1,747E-05 5,65E-04 ! cell cycle checkpoint GO:0000075 42 41 4,000 1,786E-05 5,674E-04 ! wound healing GO:0042060 74 70 5,000 1,941E-05 6,064E-04 ! cell-substrate adhesion GO:0031589 43 42 4,000 2,014E-05 6,187E-04 ! DNA integrity checkpoint GO:0031570 21 21 3,000 2,126E-05 6,423E-04 ! developmental induction GO:0031128 8 8 2,000 2,78E-05 8,262E-04 GO:0045168|cell-cell signaling involved in cell fate specification, ! phosphoinositide-mediated signaling GO:0048015 45 45 4,000 2,84E-05 8,308E-04 ! regulation of membrane potential GO:0042391 46 46 4,000 3,167E-05 9,119E-04 ! positive regulation of cell size GO:0045793 9 9 2,000 4,145E-05 1,175E-03 ! MAPKKK cascade GO:0000165 82 81 5,000 4,486E-05 1,253E-03 ! negative regulation of cell migration GO:0030336 26 26 3,000 5,152E-05 1,417E-03 ! interphase of mitotic cell cycle GO:0051329 52 51 4,000 5,261E-05 1,426E-03 GO:0051325|interphase, ! cell fate commitment GO:0045165 52 52 4,000 5,785E-05 1,545E-03 ! regulation of body fluid levels GO:0050878 55 52 4,000 5,785E-05 1,523E-03 ! epidermis morphogenesis GO:0048730 10 10 2,000 5,888E-05 1,528E-03 ! cell-substrate junction assembly GO:0007044 11 10 2,000 5,888E-05 1,507E-03 ! positive regulation of neuron apoptosis GO:0043525 10 10 2,000 5,888E-05 1,486E-03 ! mesenchymal cell development GO:0014031 29 27 3,000 6,012E-05 1,497E-03 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! protein amino acid autophosphorylation GO:0046777 28 28 3,000 6,971E-05 1,713E-03 ! positive regulation of cell cycle GO:0045787 29 29 3,000 8,038E-05 1,949E-03 ! branching morphogenesis of a tube GO:0048754 29 29 3,000 8,038E-05 1,924E-03 ! regulation of epithelial cell proliferation GO:0050678 29 29 3,000 8,038E-05 1,899E-03 ! skin development GO:0043588 11 11 2,000 8,049E-05 1,878E-03 ! hindbrain development GO:0030902 11 11 2,000 8,049E-05 1,854E-03 ! reproductive developmental process GO:0003006 56 56 4,000 8,295E-05 1,887E-03 ! negative regulation of cell cycle GO:0045786 92 91 5,000 8,655E-05 1,945E-03 ! B cell activation GO:0042113 31 31 3,000 1,052E-04 2,336E-03 ! regulation of DNA replication GO:0006275 32 31 3,000 1,052E-04 2,308E-03 ! negative regulation of cell motion GO:0051271 31 31 3,000 1,052E-04 2,281E-03 ! renal system process GO:0003014 12 12 2,000 1,067E-04 2,287E-03 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 2,000 1,067E-04 2,26E-03 ! positive regulation of multicellular organism growth GO:0040018 12 12 2,000 1,067E-04 2,235E-03 ! regulation of cell development GO:0060284 60 59 4,000 1,067E-04 2,21E-03 ! regulation of cell growth GO:0001558 97 96 5,000 1,167E-04 2,389E-03 ! morphogenesis of a branching structure GO:0001763 32 32 3,000 1,195E-04 2,42E-03 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 4,000 1,253E-04 2,509E-03 ! blood circulation GO:0008015 99 98 5,000 1,308E-04 2,593E-03 GO:0003013|circulatory system process, ! activation of protein kinase activity GO:0032147 35 33 3,000 1,352E-04 2,65E-03 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 2,000 1,379E-04 2,675E-03 ! mitochondrial membrane organization GO:0007006 13 13 2,000 1,379E-04 2,648E-03 ! actin filament bundle formation GO:0051017 13 13 2,000 1,379E-04 2,62E-03 ! cell aging GO:0007569 13 13 2,000 1,379E-04 2,594E-03 ! regulation of endothelial cell migration GO:0010594 13 13 2,000 1,379E-04 2,567E-03 ! regulation of cell-substrate adhesion GO:0010810 14 13 2,000 1,379E-04 2,542E-03 GO:0001952|regulation of cell-matrix adhesion, ! protein tetramerization GO:0051262 13 13 2,000 1,379E-04 2,516E-03 ! response to peptide hormone stimulus GO:0043434 36 34 3,000 1,523E-04 2,751E-03 ! regulation of hormone levels GO:0010817 66 65 4,000 1,697E-04 3,036E-03 ! regulation of vasoconstriction GO:0019229 14 14 2,000 1,745E-04 3,092E-03 ! collagen fibril organization GO:0030199 14 14 2,000 1,745E-04 3,063E-03 ! regulation of mitosis GO:0007088 37 36 3,000 1,911E-04 3,322E-03 GO:0051783|regulation of nuclear division, ! coagulation GO:0050817 39 36 3,000 1,911E-04 3,291E-03 GO:0007596|blood coagulation, ! negative regulation of protein kinase activity GO:0006469 37 37 3,000 2,13E-04 3,634E-03 ! insulin receptor signaling pathway GO:0008286 17 15 2,000 2,169E-04 3,667E-03 ! response to ionizing radiation GO:0010212 16 15 2,000 2,169E-04 3,634E-03 ! regionalization GO:0003002 70 69 4,000 2,252E-04 3,739E-03 ! negative regulation of kinase activity GO:0033673 38 38 3,000 2,366E-04 3,893E-03 ! hemostasis GO:0007599 42 39 3,000 2,62E-04 4,274E-03 ! activation of MAPK activity GO:0000187 39 39 3,000 2,62E-04 4,236E-03 ! regulation of MAPKKK cascade GO:0043408 41 39 3,000 2,62E-04 4,199E-03 ! positive regulation of mitosis GO:0045840 16 16 2,000 2,654E-04 4,216E-03 GO:0051785|positive regulation of nuclear division, ! segmentation GO:0035282 17 16 2,000 2,654E-04 4,18E-03 ! cell fate specification GO:0001708 16 16 2,000 2,654E-04 4,145E-03 ! regulation of JUN kinase activity GO:0043506 17 16 2,000 2,654E-04 4,11E-03 GO:0043507|positive regulation of JUN kinase activity, ! positive regulation of hydrolase activity GO:0051345 72 72 4,000 2,752E-04 4,227E-03 ! negative regulation of transferase activity GO:0051348 40 40 3,000 2,894E-04 4,408E-03 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 2,000 3,204E-04 4,84E-03 ! myelination GO:0042552 17 17 2,000 3,204E-04 4,801E-03 ! glucose transport GO:0015758 17 17 2,000 3,204E-04 4,762E-03 ! cell junction assembly GO:0034329 18 17 2,000 3,204E-04 4,724E-03 ! negative regulation of cell development GO:0010721 18 17 2,000 3,204E-04 4,687E-03 GO:0050768|negative regulation of neurogenesis, ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 2,000 3,823E-04 5,547E-03 ! hexose transport GO:0008645 18 18 2,000 3,823E-04 5,504E-03 GO:0015749|monosaccharide transport, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 2,000 3,823E-04 5,461E-03 ! B cell differentiation GO:0030183 18 18 2,000 3,823E-04 5,419E-03 ! ensheathment of neurons GO:0007272 18 18 2,000 3,823E-04 5,378E-03 GO:0008366|axon ensheathment, ! reproductive structure development GO:0048608 43 43 3,000 3,838E-04 5,358E-03 ! mitochondrion organization GO:0007005 44 43 3,000 3,838E-04 5,318E-03 ! regulation of protein modification process GO:0031399 79 78 4,000 4,002E-04 5,504E-03 ! metanephros development GO:0001656 19 19 2,000 4,513E-04 6,161E-03 ! regulation of pH GO:0006885 19 19 2,000 4,513E-04 6,116E-03 ! regulation of striated muscle tissue development GO:0016202 20 19 2,000 4,513E-04 6,072E-03 ! peripheral nervous system development GO:0007422 19 19 2,000 4,513E-04 6,028E-03 ! dorsal/ventral pattern formation GO:0009953 19 19 2,000 4,513E-04 5,984E-03 ! tube morphogenesis GO:0035239 47 46 3,000 4,984E-04 6,561E-03 ! cellular response to hormone stimulus GO:0032870 48 46 3,000 4,984E-04 6,514E-03 ! regulation of muscle development GO:0048634 21 20 2,000 5,279E-04 6,852E-03 ! negative regulation of neuron apoptosis GO:0043524 21 20 2,000 5,279E-04 6,804E-03 ! actin filament organization GO:0007015 50 48 3,000 5,871E-04 7,514E-03 ! regulation of cell cycle process GO:0010564 50 48 3,000 5,871E-04 7,463E-03 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 2,000 6,124E-04 7,73E-03 ! regulation of action potential in neuron GO:0019228 21 21 2,000 6,124E-04 7,677E-03 ! regulation of multicellular organism growth GO:0040014 21 21 2,000 6,124E-04 7,626E-03 ! negative regulation of hydrolase activity GO:0051346 21 21 2,000 6,124E-04 7,574E-03 ! cellular response to insulin stimulus GO:0032869 23 21 2,000 6,124E-04 7,524E-03 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 6,406E-04 7,819E-03 ! metencephalon development GO:0022037 5 5 1,000 6,406E-04 7,768E-03 ! 2-oxoglutarate metabolic process GO:0006103 5 5 1,000 6,406E-04 7,717E-03 ! middle ear morphogenesis GO:0042474 5 5 1,000 6,406E-04 7,667E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 1,000 6,406E-04 7,617E-03 ! adrenal gland development GO:0030325 5 5 1,000 6,406E-04 7,568E-03 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 1,000 6,406E-04 7,52E-03 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! astrocyte differentiation GO:0048708 5 5 1,000 6,406E-04 7,473E-03 ! muscle cell migration GO:0014812 5 5 1,000 6,406E-04 7,426E-03 ! phasic smooth muscle contraction GO:0014821 5 5 1,000 6,406E-04 7,379E-03 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 6,406E-04 7,333E-03 ! fear response GO:0042596 5 5 1,000 6,406E-04 7,288E-03 ! Schwann cell differentiation GO:0014037 5 5 1,000 6,406E-04 7,243E-03 ! protein heterooligomerization GO:0051291 5 5 1,000 6,406E-04 7,199E-03 ! regulation of gliogenesis GO:0014013 5 5 1,000 6,406E-04 7,156E-03 GO:0045685|regulation of glial cell differentiation, ! response to UV-B GO:0010224 5 5 1,000 6,406E-04 7,112E-03 ! regulation of mitochondrial membrane potential GO:0051881 5 5 1,000 6,406E-04 7,07E-03 ! cellular pigmentation GO:0033059 5 5 1,000 6,406E-04 7,028E-03 ! peptidyl-lysine modification GO:0018205 5 5 1,000 6,406E-04 6,986E-03 ! peptidyl-histidine modification GO:0018202 5 5 1,000 6,406E-04 6,945E-03 ! oocyte differentiation GO:0009994 5 5 1,000 6,406E-04 6,905E-03 GO:0048599|oocyte development, ! regulation of protein homodimerization activity GO:0043496 6 5 1,000 6,406E-04 6,864E-03 ! spleen development GO:0048536 5 5 1,000 6,406E-04 6,825E-03 ! positive regulation of smooth muscle contraction GO:0045987 5 5 1,000 6,406E-04 6,785E-03 ! response to nicotine GO:0035094 5 5 1,000 6,406E-04 6,747E-03 ! regulation of DNA metabolic process GO:0051052 51 50 3,000 6,866E-04 7,19E-03 ! regulation of neurogenesis GO:0050767 51 50 3,000 6,866E-04 7,149E-03 ! anterior/posterior pattern formation GO:0009952 51 50 3,000 6,866E-04 7,109E-03 ! cell junction organization GO:0034330 23 22 2,000 7,05E-04 7,258E-03 ! spindle organization GO:0007051 22 22 2,000 7,05E-04 7,218E-03 ! chemotaxis GO:0006935 90 89 4,000 7,352E-04 7,486E-03 GO:0042330|taxis, ! brain development GO:0007420 91 90 4,000 7,737E-04 7,834E-03 ! mitotic cell cycle checkpoint GO:0007093 24 23 2,000 8,061E-04 8,118E-03 ! monovalent inorganic cation homeostasis GO:0055067 23 23 2,000 8,061E-04 8,074E-03 ! calcium-mediated signaling GO:0019722 23 23 2,000 8,061E-04 8,03E-03 ! regulation of JNK cascade GO:0046328 25 23 2,000 8,061E-04 7,987E-03 ! tissue morphogenesis GO:0048729 94 93 4,000 8,981E-04 8,851E-03 ! mitochondrial transport GO:0006839 24 24 2,000 9,159E-04 8,979E-03 ! regulation of action potential GO:0001508 24 24 2,000 9,159E-04 8,931E-03 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 2,000 9,159E-04 8,884E-03 ! glucose homeostasis GO:0042593 24 24 2,000 9,159E-04 8,838E-03 GO:0033500|carbohydrate homeostasis, ! T cell differentiation GO:0030217 24 24 2,000 9,159E-04 8,792E-03 ! androgen receptor signaling pathway GO:0030521 24 24 2,000 9,159E-04 8,746E-03 ! protein amino acid dephosphorylation GO:0006470 55 54 3,000 9,204E-04 8,743E-03 ! hormone metabolic process GO:0042445 55 54 3,000 9,204E-04 8,699E-03 ! regulation of response to stress GO:0080134 97 94 4,000 9,427E-04 8,865E-03 ! blood vessel development GO:0001568 95 94 4,000 9,427E-04 8,82E-03 ! pattern specification process GO:0007389 96 94 4,000 9,427E-04 8,775E-03 ! epidermis development GO:0008544 94 94 4,000 9,427E-04 8,731E-03 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 1,000 9,559E-04 8,809E-03 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 9,559E-04 8,765E-03 GO:0018409|peptide or protein amino-terminal blocking, ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 1,000 9,559E-04 8,722E-03 GO:0016446|somatic hypermutation of immunoglobulin genes, ! virus-host interaction GO:0019048 6 6 1,000 9,559E-04 8,679E-03 ! regulation of lipid kinase activity GO:0043550 6 6 1,000 9,559E-04 8,636E-03 ! succinate metabolic process GO:0006105 7 6 1,000 9,559E-04 8,594E-03 ! artery development GO:0060840 6 6 1,000 9,559E-04 8,552E-03 GO:0048844|artery morphogenesis, ! positive regulation of heart contraction GO:0045823 6 6 1,000 9,559E-04 8,511E-03 ! positive regulation of cell growth GO:0030307 6 6 1,000 9,559E-04 8,47E-03 ! inositol phosphate-mediated signaling GO:0048016 6 6 1,000 9,559E-04 8,429E-03 ! ER overload response GO:0006983 6 6 1,000 9,559E-04 8,389E-03 ! vascular smooth muscle contraction GO:0014829 6 6 1,000 9,559E-04 8,35E-03 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 9,559E-04 8,31E-03 GO:0070667|negative regulation of mast cell proliferation, ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 1,000 9,559E-04 8,271E-03 ! regulation of heart rate GO:0002027 6 6 1,000 9,559E-04 8,232E-03 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 9,559E-04 8,194E-03 ! negative regulation of ossification GO:0030279 6 6 1,000 9,559E-04 8,156E-03 ! regulation of bone resorption GO:0045124 6 6 1,000 9,559E-04 8,119E-03 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 9,559E-04 8,081E-03 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 1,000 9,559E-04 8,045E-03 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 9,559E-04 8,008E-03 ! renal water homeostasis GO:0003091 6 6 1,000 9,559E-04 7,972E-03 ! positive regulation of Ras GTPase activity GO:0032320 6 6 1,000 9,559E-04 7,936E-03 ! thymus development GO:0048538 6 6 1,000 9,559E-04 7,9E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 9,559E-04 7,865E-03 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 9,559E-04 7,83E-03 ! localization within membrane GO:0051668 6 6 1,000 9,559E-04 7,795E-03 ! regulation of cell adhesion GO:0030155 56 55 3,000 9,866E-04 8,01E-03 ! regulation of gene-specific transcription GO:0032583 25 25 2,000 1,035E-03 8,365E-03 ! vasculature development GO:0001944 97 96 4,000 1,037E-03 8,345E-03 ! extracellular structure organization GO:0043062 56 56 3,000 1,056E-03 8,463E-03 ! regulation of nervous system development GO:0051960 57 56 3,000 1,056E-03 8,426E-03 ! induction of apoptosis by intracellular signals GO:0008629 26 26 2,000 1,163E-03 9,24E-03 ! double-strand break repair GO:0006302 27 26 2,000 1,163E-03 9,2E-03 ! germ cell development GO:0007281 27 26 2,000 1,163E-03 9,161E-03 ! response to insulin stimulus GO:0032868 28 26 2,000 1,163E-03 9,122E-03 ! ectoderm development GO:0007398 99 99 4,000 1,191E-03 9,302E-03 ! response to hormone stimulus GO:0009725 102 100 4,000 1,246E-03 9,69E-03 ! dephosphorylation GO:0016311 60 59 3,000 1,285E-03 9,952E-03 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 1,000 1,331E-03 0,01026599 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 1,000 1,331E-03 0,01022321 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 1,331E-03 0,01018079 ! positive regulation of GTPase activity GO:0043547 7 7 1,000 1,331E-03 0,01013872 ! hair follicle morphogenesis GO:0031069 7 7 1,000 1,331E-03 0,010097 ! oxaloacetate metabolic process GO:0006107 7 7 1,000 1,331E-03 0,01005562 ! keratinocyte proliferation GO:0043616 7 7 1,000 1,331E-03 0,01001458 ! axis specification GO:0009798 7 7 1,000 1,331E-03 9,974E-03 ! visual behavior GO:0007632 7 7 1,000 1,331E-03 9,933E-03 GO:0008542|visual learning, ! digestive system development GO:0055123 7 7 1,000 1,331E-03 9,893E-03 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! regulation of skeletal muscle fiber development GO:0048742 7 7 1,000 1,331E-03 9,854E-03 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 1,331E-03 9,814E-03 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! response to X-ray GO:0010165 7 7 1,000 1,331E-03 9,775E-03 ! regulation of intracellular pH GO:0051453 7 7 1,000 1,331E-03 9,736E-03 ! DNA integration GO:0015074 7 7 1,000 1,331E-03 9,698E-03 ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 1,331E-03 9,66E-03 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 1,000 1,331E-03 9,622E-03 ! alpha-beta T cell differentiation GO:0046632 7 7 1,000 1,331E-03 9,584E-03 ! cranial nerve development GO:0021545 7 7 1,000 1,331E-03 9,547E-03 ! multicellular organismal water homeostasis GO:0050891 7 7 1,000 1,331E-03 9,51E-03 ! cAMP biosynthetic process GO:0006171 7 7 1,000 1,331E-03 9,473E-03 ! negative regulation of T cell activation GO:0050868 7 7 1,000 1,331E-03 9,437E-03 ! carbohydrate transport GO:0008643 28 28 2,000 1,449E-03 0,01022982 ! morphogenesis of an epithelium GO:0002009 63 62 3,000 1,547E-03 0,01088286 GO:0060429|epithelium development, ! regulation of response to external stimulus GO:0032101 65 64 3,000 1,741E-03 0,01220057 ! regulation of skeletal muscle tissue development GO:0048641 8 8 1,000 1,766E-03 0,01232709 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 1,766E-03 0,01228058 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 1,000 1,766E-03 0,01223441 ! T cell selection GO:0045058 8 8 1,000 1,766E-03 0,01218859 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 1,000 1,766E-03 0,01214311 ! DNA duplex unwinding GO:0032508 8 8 1,000 1,766E-03 0,01209796 GO:0032392|DNA geometric change, ! phosphagen metabolic process GO:0006599 8 8 1,000 1,766E-03 0,01205316 GO:0006600|creatine metabolic process, ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 1,766E-03 0,01200868 ! sex determination GO:0007530 8 8 1,000 1,766E-03 0,01196453 ! negative regulation of mitotic cell cycle GO:0045930 9 8 1,000 1,766E-03 0,0119207 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 1,766E-03 0,0118772 ! alpha-beta T cell activation GO:0046631 8 8 1,000 1,766E-03 0,01183401 ! vasoconstriction GO:0042310 8 8 1,000 1,766E-03 0,01179113 ! immunoglobulin production during immune response GO:0002381 8 8 1,000 1,766E-03 0,01174856 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! T cell homeostasis GO:0043029 8 8 1,000 1,766E-03 0,0117063 ! peptidyl-serine modification GO:0018209 8 8 1,000 1,766E-03 0,01166435 ! water homeostasis GO:0030104 8 8 1,000 1,766E-03 0,01162269 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 1,000 1,766E-03 0,01158133 ! branched chain family amino acid metabolic process GO:0009081 8 8 1,000 1,766E-03 0,01154026 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 1,766E-03 0,01149948 ! peptide hormone secretion GO:0030072 8 8 1,000 1,766E-03 0,01145899 ! peptide hormone processing GO:0016486 8 8 1,000 1,766E-03 0,01141878 ! response to reactive oxygen species GO:0000302 31 30 2,000 1,775E-03 0,01143735 ! activation of phospholipase C activity GO:0007202 30 30 2,000 1,775E-03 0,0113975 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 31 31 2,000 1,954E-03 0,01250271 ! aging GO:0007568 32 31 2,000 1,954E-03 0,01245945 ! extracellular matrix organization GO:0030198 31 31 2,000 1,954E-03 0,01241648 ! epidermal cell differentiation GO:0009913 31 31 2,000 1,954E-03 0,01237382 ! Ras protein signal transduction GO:0007265 69 67 3,000 2,063E-03 0,0130193 ! negative regulation of cell growth GO:0030308 32 32 2,000 2,144E-03 0,0134829 ! regulation of phospholipase activity GO:0010517 32 32 2,000 2,144E-03 0,01343704 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 2,000 2,144E-03 0,01339149 ! kidney development GO:0001822 32 32 2,000 2,144E-03 0,01334625 ! positive regulation of lipase activity GO:0060193 32 32 2,000 2,144E-03 0,01330131 ! embryonic pattern specification GO:0009880 10 9 1,000 2,258E-03 0,01396758 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 2,258E-03 0,01392087 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 2,258E-03 0,01387447 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 1,000 2,258E-03 0,01382837 ! response to alkaloid GO:0043279 10 9 1,000 2,258E-03 0,01378258 ! response to ethanol GO:0045471 9 9 1,000 2,258E-03 0,01373709 ! activation of pro-apoptotic gene products GO:0008633 9 9 1,000 2,258E-03 0,01369191 ! cerebral cortex development GO:0021987 9 9 1,000 2,258E-03 0,01364702 ! response to osmotic stress GO:0006970 9 9 1,000 2,258E-03 0,01360242 ! pigmentation during development GO:0048066 9 9 1,000 2,258E-03 0,01355811 ! negative regulation of caspase activity GO:0043154 9 9 1,000 2,258E-03 0,01351409 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 1,000 2,258E-03 0,01347035 GO:0060675|ureteric bud morphogenesis, ! peptide secretion GO:0002790 9 9 1,000 2,258E-03 0,0134269 ! negative regulation of protein import into nucleus GO:0042308 9 9 1,000 2,258E-03 0,01338373 ! T cell differentiation in the thymus GO:0033077 9 9 1,000 2,258E-03 0,01334083 ! regulation of cellular pH GO:0030641 9 9 1,000 2,258E-03 0,01329821 ! histone acetylation GO:0016573 9 9 1,000 2,258E-03 0,01325586 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 2,258E-03 0,01321378 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 1,000 2,258E-03 0,01317196 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 2,258E-03 0,01313041 ! defense response to virus GO:0051607 9 9 1,000 2,258E-03 0,01308912 ! response to nutrient levels GO:0031667 69 69 3,000 2,299E-03 0,01328076 ! negative regulation of cell size GO:0045792 33 33 2,000 2,344E-03 0,01350196 ! regulation of cellular response to stress GO:0080135 35 33 2,000 2,344E-03 0,01345989 ! muscle tissue development GO:0060537 72 70 3,000 2,423E-03 0,01387081 ! regulation of bone remodeling GO:0046850 34 34 2,000 2,556E-03 0,01458697 ! ear development GO:0043583 34 34 2,000 2,556E-03 0,01454195 ! sensory organ development GO:0007423 72 72 3,000 2,687E-03 0,0152357 ! response to extracellular stimulus GO:0009991 72 72 3,000 2,687E-03 0,01518897 ! positive regulation of phosphorylation GO:0042327 35 35 2,000 2,78E-03 0,01566904 ! regulation of tissue remodeling GO:0034103 35 35 2,000 2,78E-03 0,01562127 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 2,808E-03 0,01573191 ! reciprocal meiotic recombination GO:0007131 10 10 1,000 2,808E-03 0,01568423 ! hormone secretion GO:0046879 10 10 1,000 2,808E-03 0,01563685 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 2,808E-03 0,01558975 ! cAMP metabolic process GO:0046058 10 10 1,000 2,808E-03 0,01554293 ! glial cell development GO:0021782 10 10 1,000 2,808E-03 0,0154964 ! neuromuscular junction development GO:0007528 10 10 1,000 2,808E-03 0,01545014 ! regulation of protein binding GO:0043393 11 10 1,000 2,808E-03 0,01540416 ! mismatch repair GO:0006298 10 10 1,000 2,808E-03 0,01535845 ! gland morphogenesis GO:0022612 10 10 1,000 2,808E-03 0,01531301 ! regulation of BMP signaling pathway GO:0030510 10 10 1,000 2,808E-03 0,01526784 ! lymphocyte homeostasis GO:0002260 10 10 1,000 2,808E-03 0,01522293 ! nerve development GO:0021675 10 10 1,000 2,808E-03 0,01517829 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 2,808E-03 0,01513391 ! gut development GO:0048565 10 10 1,000 2,808E-03 0,01508979 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 2,808E-03 0,01504592 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 2,000 3,015E-03 0,01610886 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 2,000 3,015E-03 0,01606231 ! positive regulation of organelle organization GO:0010638 36 36 2,000 3,015E-03 0,01601602 ! regulation of lipase activity GO:0060191 36 36 2,000 3,015E-03 0,01597 ! response to oxidative stress GO:0006979 76 75 3,000 3,117E-03 0,01646288 ! response to drug GO:0042493 37 37 2,000 3,263E-03 0,01718086 ! negative regulation of growth GO:0045926 37 37 2,000 3,263E-03 0,01713191 ! positive regulation of multicellular organismal process GO:0051240 76 76 3,000 3,271E-03 0,01712624 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 1,000 3,415E-03 0,01782722 ! G1 phase of mitotic cell cycle GO:0000080 12 11 1,000 3,415E-03 0,01777686 ! determination of bilateral symmetry GO:0009855 11 11 1,000 3,415E-03 0,01772679 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 1,000 3,415E-03 0,01767699 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 1,000 3,415E-03 0,01762748 ! signal complex assembly GO:0007172 11 11 1,000 3,415E-03 0,01757824 ! protein amino acid acetylation GO:0006473 11 11 1,000 3,415E-03 0,01752928 ! negative regulation of endothelial cell proliferation GO:0001937 11 11 1,000 3,415E-03 0,01748058 ! regulation of viral genome replication GO:0045069 11 11 1,000 3,415E-03 0,01743216 ! spinal cord development GO:0021510 11 11 1,000 3,415E-03 0,01738401 ! activation of MAPKK activity GO:0000186 12 11 1,000 3,415E-03 0,01733612 ! smooth muscle contraction GO:0006939 11 11 1,000 3,415E-03 0,01728849 ! cellular response to starvation GO:0009267 11 11 1,000 3,415E-03 0,01724112 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 3,415E-03 0,01719402 ! body fluid secretion GO:0007589 11 11 1,000 3,415E-03 0,01714717 ! G1/S transition checkpoint GO:0031575 12 11 1,000 3,415E-03 0,01710057 ! interaction with host GO:0051701 11 11 1,000 3,415E-03 0,01705423 ! membrane depolarization GO:0051899 11 11 1,000 3,415E-03 0,01700814 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 3,415E-03 0,01696229 ! oogenesis GO:0048477 11 11 1,000 3,415E-03 0,01691669 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 3,415E-03 0,01687134 GO:0006109|regulation of carbohydrate metabolic process, ! endocrine process GO:0050886 11 11 1,000 3,415E-03 0,01682623 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! somatic diversification of immunoglobulins GO:0016445 11 11 1,000 3,415E-03 0,01678136 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 3,415E-03 0,01673673 ! cell morphogenesis involved in differentiation GO:0000904 82 77 3,000 3,43E-03 0,0167658 ! steroid hormone receptor signaling pathway GO:0030518 38 38 2,000 3,522E-03 0,01717289 ! regulation of homeostatic process GO:0032844 38 38 2,000 3,522E-03 0,01712758 ! regulation of cAMP biosynthetic process GO:0030817 39 39 2,000 3,794E-03 0,01840014 ! nucleotide-excision repair GO:0006289 40 39 2,000 3,794E-03 0,01835184 ! lymphocyte differentiation GO:0030098 39 39 2,000 3,794E-03 0,0183038 ! protein oligomerization GO:0051259 39 39 2,000 3,794E-03 0,01825601 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 1,000 4,076E-03 0,01956324 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 1,000 4,076E-03 0,01951242 ! C21-steroid hormone metabolic process GO:0008207 13 12 1,000 4,076E-03 0,01946187 ! regulation of muscle cell differentiation GO:0051147 13 12 1,000 4,076E-03 0,01941158 ! negative regulation of peptidase activity GO:0010466 12 12 1,000 4,076E-03 0,01936155 ! GPI anchor biosynthetic process GO:0006506 12 12 1,000 4,076E-03 0,01931178 GO:0006505|GPI anchor metabolic process, ! osteoblast differentiation GO:0001649 12 12 1,000 4,076E-03 0,01926226 ! male gonad development GO:0008584 12 12 1,000 4,076E-03 0,019213 ! pallium development GO:0021543 13 12 1,000 4,076E-03 0,01916399 ! regulation of chromosome organization GO:0033044 12 12 1,000 4,076E-03 0,01911522 ! somitogenesis GO:0001756 13 12 1,000 4,076E-03 0,01906671 ! G1 phase GO:0051318 13 12 1,000 4,076E-03 0,01901844 ! hormone transport GO:0009914 12 12 1,000 4,076E-03 0,01897041 ! spermatid differentiation GO:0048515 13 12 1,000 4,076E-03 0,01892263 GO:0007286|spermatid development, ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 1,000 4,076E-03 0,01887508 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 4,076E-03 0,01882778 ! negative regulation of translation GO:0017148 12 12 1,000 4,076E-03 0,01878071 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 4,076E-03 0,01873387 ! regulation of cAMP metabolic process GO:0030814 40 40 2,000 4,078E-03 0,01869585 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 2,000 4,078E-03 0,01864946 ! lymphocyte activation GO:0046649 82 81 3,000 4,116E-03 0,01877846 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 2,000 4,375E-03 0,0199079 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of caspase activity GO:0043281 41 41 2,000 4,375E-03 0,01985886 ! blood vessel morphogenesis GO:0048514 84 83 3,000 4,492E-03 0,02034267 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 2,000 4,684E-03 0,02115995 ! regulation of endopeptidase activity GO:0052548 42 42 2,000 4,684E-03 0,02110822 ! forebrain development GO:0030900 43 42 2,000 4,684E-03 0,02105673 ! positive regulation of DNA replication GO:0045740 14 13 1,000 4,792E-03 0,02148891 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 4,792E-03 0,02143675 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 1,000 4,792E-03 0,02138484 GO:0016444|somatic cell DNA recombination, ! negative regulation of hormone secretion GO:0046888 13 13 1,000 4,792E-03 0,02133319 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 1,000 4,792E-03 0,02128179 GO:0019692|deoxyribose phosphate metabolic process, ! positive regulation of JAK-STAT cascade GO:0046427 13 13 1,000 4,792E-03 0,02123063 ! regeneration GO:0031099 13 13 1,000 4,792E-03 0,02117971 ! post-embryonic development GO:0009791 14 13 1,000 4,792E-03 0,02112905 ! patterning of blood vessels GO:0001569 13 13 1,000 4,792E-03 0,02107862 ! negative regulation of DNA replication GO:0008156 13 13 1,000 4,792E-03 0,02102843 ! response to corticosteroid stimulus GO:0031960 13 13 1,000 4,792E-03 0,02097848 GO:0051384|response to glucocorticoid stimulus, ! ureteric bud development GO:0001657 13 13 1,000 4,792E-03 0,02092877 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 4,792E-03 0,02087929 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 4,792E-03 0,02083005 ! negative regulation of protein kinase cascade GO:0010741 13 13 1,000 4,792E-03 0,02078104 ! regulation of viral reproduction GO:0050792 13 13 1,000 4,792E-03 0,02073226 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 1,000 4,792E-03 0,0206837 ! neutrophil chemotaxis GO:0030593 14 13 1,000 4,792E-03 0,02063538 ! immunoglobulin production GO:0002377 13 13 1,000 4,792E-03 0,02058727 GO:0002440|production of molecular mediator of immune response, ! negative regulation of intracellular transport GO:0032387 13 13 1,000 4,792E-03 0,0205394 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 4,792E-03 0,02049174 ! response to cytokine stimulus GO:0034097 13 13 1,000 4,792E-03 0,02044431 ! activation of JUN kinase activity GO:0007257 13 13 1,000 4,792E-03 0,02039709 ! camera-type eye morphogenesis GO:0048593 13 13 1,000 4,792E-03 0,02035009 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 1,000 4,792E-03 0,02030331 ! tissue homeostasis GO:0001894 13 13 1,000 4,792E-03 0,02025675 GO:0048871|multicellular organismal homeostasis, ! regulation of nucleotide metabolic process GO:0006140 43 43 2,000 5,007E-03 0,02111603 ! humoral immune response GO:0006959 44 44 2,000 5,343E-03 0,02248018 ! protein amino acid acylation GO:0043543 14 14 1,000 5,562E-03 0,02334927 ! hair cycle GO:0042633 14 14 1,000 5,562E-03 0,0232962 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! response to retinoic acid GO:0032526 14 14 1,000 5,562E-03 0,02324337 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 1,000 5,562E-03 0,02319079 ! D-ribose metabolic process GO:0006014 14 14 1,000 5,562E-03 0,02313844 ! peptide transport GO:0015833 14 14 1,000 5,562E-03 0,02308632 ! base-excision repair GO:0006284 14 14 1,000 5,562E-03 0,02303445 ! response to organic cyclic substance GO:0014070 15 14 1,000 5,562E-03 0,0229828 ! Wnt receptor signaling pathway GO:0016055 46 45 2,000 5,691E-03 0,02346613 ! regulation of peptidase activity GO:0052547 46 46 2,000 6,054E-03 0,02490423 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 2,000 6,054E-03 0,02484877 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 6,384E-03 0,02614624 ! response to vitamin GO:0033273 15 15 1,000 6,384E-03 0,02608827 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 6,384E-03 0,02603055 ! ovarian follicle development GO:0001541 15 15 1,000 6,384E-03 0,02597309 ! regulation of smooth muscle contraction GO:0006940 15 15 1,000 6,384E-03 0,02591588 ! deoxyribonucleotide metabolic process GO:0009262 15 15 1,000 6,384E-03 0,02585892 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 6,384E-03 0,02580221 ! response to starvation GO:0042594 15 15 1,000 6,384E-03 0,02574575 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 1,000 6,384E-03 0,02568954 ! leukocyte homeostasis GO:0001776 15 15 1,000 6,384E-03 0,02563357 ! somatic diversification of immune receptors GO:0002200 15 15 1,000 6,384E-03 0,02557784 ! negative regulation of cell activation GO:0050866 15 15 1,000 6,384E-03 0,02552236 ! regulation of blood pressure GO:0008217 48 47 2,000 6,43E-03 0,02564885 ! sex differentiation GO:0007548 47 47 2,000 6,43E-03 0,02559346 ! regulation of catabolic process GO:0009894 48 47 2,000 6,43E-03 0,0255383 ! DNA recombination GO:0006310 48 48 2,000 6,819E-03 0,02702713 ! leukocyte differentiation GO:0002521 50 49 2,000 7,222E-03 0,02856408 ! ossification GO:0001503 50 49 2,000 7,222E-03 0,02850292 GO:0060348|bone development, ! skeletal muscle tissue development GO:0007519 50 49 2,000 7,222E-03 0,02844201 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 2,000 7,222E-03 0,02838137 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 1,000 7,258E-03 0,0284612 ! learning GO:0007612 16 16 1,000 7,258E-03 0,02840078 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 7,258E-03 0,0283406 ! cellular response to reactive oxygen species GO:0034614 16 16 1,000 7,258E-03 0,02828069 ! positive regulation of cytoskeleton organization GO:0051495 16 16 1,000 7,258E-03 0,02822102 ! triglyceride metabolic process GO:0006641 16 16 1,000 7,258E-03 0,02816161 ! positive regulation of cell development GO:0010720 16 16 1,000 7,258E-03 0,02810245 ! lymphocyte proliferation GO:0046651 16 16 1,000 7,258E-03 0,02804353 ! regulation of systemic arterial blood pressure GO:0003073 17 16 1,000 7,258E-03 0,02798486 ! pentose metabolic process GO:0019321 16 16 1,000 7,258E-03 0,02792644 ! cellular response to nutrient levels GO:0031669 16 16 1,000 7,258E-03 0,02786826 ! positive regulation of catabolic process GO:0009896 16 16 1,000 7,258E-03 0,02781032 ! negative regulation of transport GO:0051051 51 50 2,000 7,64E-03 0,02921105 ! T cell activation GO:0042110 51 50 2,000 7,64E-03 0,02915057 ! transcription initiation GO:0006352 50 50 2,000 7,64E-03 0,02909034 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 8,183E-03 0,03109608 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 8,183E-03 0,0310321 ! phosphoinositide biosynthetic process GO:0046489 17 17 1,000 8,183E-03 0,03096838 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 1,000 8,183E-03 0,03090492 ! dicarboxylic acid metabolic process GO:0043648 18 17 1,000 8,183E-03 0,03084172 ! embryonic skeletal system morphogenesis GO:0048704 17 17 1,000 8,183E-03 0,03077878 ! development of primary male sexual characteristics GO:0046546 17 17 1,000 8,183E-03 0,03071609 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 1,000 8,183E-03 0,03065366 ! neural crest cell development GO:0014032 19 17 1,000 8,183E-03 0,03059148 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 1,000 8,183E-03 0,03052956 ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 8,183E-03 0,03046788 ! liver development GO:0001889 17 17 1,000 8,183E-03 0,03040645 ! muscle organ development GO:0007517 102 100 3,000 8,658E-03 0,03210762 ! hemopoiesis GO:0030097 104 100 3,000 8,658E-03 0,03204314 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 9,158E-03 0,03382512 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 1,000 9,158E-03 0,03375747 ! mononuclear cell proliferation GO:0032943 18 18 1,000 9,158E-03 0,03369009 GO:0070661|leukocyte proliferation, ! neutral lipid metabolic process GO:0006638 18 18 1,000 9,158E-03 0,03362298 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 19 18 1,000 9,158E-03 0,03355613 ! negative regulation of MAP kinase activity GO:0043407 18 18 1,000 9,158E-03 0,03348956 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 9,158E-03 0,03342324 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 9,158E-03 0,03335719 ! microtubule cytoskeleton organization GO:0000226 55 55 2,000 9,938E-03 0,0361245 ! in utero embryonic development GO:0001701 55 55 2,000 9,938E-03 0,03605338 ! negative regulation of DNA metabolic process GO:0051053 19 19 1,000 0,01018264 0,03686957 ! glial cell differentiation GO:0010001 19 19 1,000 0,01018264 0,03679728 ! regulation of JAK-STAT cascade GO:0046425 19 19 1,000 0,01018264 0,03672526 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 0,01018264 0,03665354 ! multicellular organismal metabolic process GO:0044236 19 19 1,000 0,01018264 0,03658209 ! cellular response to oxidative stress GO:0034599 19 19 1,000 0,01018264 0,03651092 ! regulation of protein stability GO:0031647 19 19 1,000 0,01018264 0,03644002 ! hormone biosynthetic process GO:0042446 19 19 1,000 0,01018264 0,0363694 ! eye morphogenesis GO:0048592 19 19 1,000 0,01018264 0,03629905 ! response to heat GO:0009408 19 19 1,000 0,01018264 0,03622898 ! regulation of binding GO:0051098 60 57 2,000 0,0109577 0,03891144 ! regulation of protein localization GO:0032880 58 57 2,000 0,0109577 0,03883661 ! organic ether metabolic process GO:0018904 20 20 1,000 0,01125539 0,03981513 GO:0006662|glycerol ether metabolic process, ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 0,01125539 0,03973886 ! cyclic nucleotide metabolic process GO:0009187 20 20 1,000 0,01125539 0,03966287 ! female gamete generation GO:0007292 20 20 1,000 0,01125539 0,03958718 ! immune effector process GO:0002252 59 59 2,000 0,01203631 0,04225318 ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 0,01237571 0,04336203 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 1,000 0,01237571 0,04327975 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! mammary gland development GO:0030879 23 21 1,000 0,01237571 0,04319778 ! protein amino acid lipidation GO:0006497 21 21 1,000 0,01237571 0,04311612 ! receptor-mediated endocytosis GO:0006898 21 21 1,000 0,01237571 0,04303477 ! ear morphogenesis GO:0042471 21 21 1,000 0,01237571 0,04295373 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 0,01237571 0,04287299 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 1,000 0,01237571 0,04279255 ! regulation of proteolysis GO:0030162 21 21 1,000 0,01237571 0,04271241 ! negative regulation of protein transport GO:0051224 21 21 1,000 0,01237571 0,04263258 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 0,01354278 0,04656594 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 0,01354278 0,04647923 ! sister chromatid segregation GO:0000819 22 22 1,000 0,01354278 0,04639284 ! cellular amide metabolic process GO:0043603 22 22 1,000 0,01354278 0,04630676 ! odontogenesis GO:0042476 22 22 1,000 0,01354278 0,04622101 ! embryonic skeletal system development GO:0048706 22 22 1,000 0,01354278 0,04613557 ! ovulation cycle process GO:0022602 22 22 1,000 0,01354278 0,04605045 ! cell chemotaxis GO:0060326 23 22 1,000 0,01354278 0,04596565 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 1,000 0,01354278 0,04588115 ! male sex differentiation GO:0046661 22 22 1,000 0,01354278 0,04579696 ! cytokinesis GO:0000910 23 22 1,000 0,01354278 0,04571309 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 1,000 0,01354278 0,04562952 ! axonogenesis GO:0007409 66 62 2,000 0,01376526 0,04629447 ! response to hydrogen peroxide GO:0042542 24 23 1,000 0,0147558 0,04953542 ! epithelial cell differentiation GO:0030855 23 23 1,000 0,0147558 0,04944535 ! regulation of hormone secretion GO:0046883 23 23 1,000 0,0147558 0,04935561 ! response to estrogen stimulus GO:0043627 23 23 1,000 0,0147558 0,0492662 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 1,000 0,0147558 0,04917711 ! endocrine system development GO:0035270 23 23 1,000 0,0147558 0,04908834 ! lipoprotein biosynthetic process GO:0042158 23 23 1,000 0,0147558 0,0489999 ! female gonad development GO:0008585 23 23 1,000 0,0147558 0,04891177 ! Rho protein signal transduction GO:0007266 24 23 1,000 0,0147558 0,04882395 ! glycerolipid metabolic process GO:0046486 65 64 2,000 0,01499258 0,04951852 ! angiogenesis GO:0001525 65 64 2,000 0,01499258 0,04942993 ! positive regulation of cellular component organization GO:0051130 65 65 2,000 0,0156288 0,0514355 ! gliogenesis GO:0042063 24 24 1,000 0,01601397 0,05260918 ! ovulation cycle GO:0042698 24 24 1,000 0,01601397 0,05251557 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 0,01601397 0,0524223 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 2,000 0,01694655 0,05537676 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! striated muscle tissue development GO:0014706 69 67 2,000 0,01694655 0,05527875 ! negative regulation of cell differentiation GO:0045596 68 67 2,000 0,01694655 0,05518108 ! negative regulation of secretion GO:0051048 26 25 1,000 0,01731651 0,05628628 ! regulation of intracellular protein transport GO:0033157 25 25 1,000 0,01731651 0,05618719 ! development of primary female sexual characteristics GO:0046545 25 25 1,000 0,01731651 0,05608844 GO:0046660|female sex differentiation, ! regulation of T cell proliferation GO:0042129 25 25 1,000 0,01731651 0,05599004 ! excretion GO:0007588 25 25 1,000 0,01731651 0,05589198 ! positive regulation of DNA binding GO:0043388 26 25 1,000 0,01731651 0,05579427 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 1,000 0,01731651 0,0556969 ! heart morphogenesis GO:0003007 25 25 1,000 0,01731651 0,05559986 ! negative regulation of immune system process GO:0002683 25 25 1,000 0,01731651 0,05550317 ! JAK-STAT cascade GO:0007259 26 25 1,000 0,01731651 0,05540681 ! positive regulation of binding GO:0051099 27 26 1,000 0,01866262 0,05961043 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 1,000 0,01866262 0,0595073 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 1,000 0,01866262 0,05940452 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01866262 0,0593021 ! regulation of blood vessel size GO:0050880 27 26 1,000 0,01866262 0,05920003 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 1,000 0,01866262 0,05909831 ! synapse organization GO:0050808 26 26 1,000 0,01866262 0,05899694 ! cell part morphogenesis GO:0032990 75 70 2,000 0,01903695 0,06007723 ! growth GO:0040007 70 70 2,000 0,01903695 0,05997453 ! calcium ion homeostasis GO:0055074 71 71 2,000 0,0197642 0,06215941 GO:0006874|cellular calcium ion homeostasis, ! negative regulation of signal transduction GO:0009968 71 71 2,000 0,0197642 0,06205351 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 1,000 0,02005156 0,06284867 ! learning or memory GO:0007611 28 27 1,000 0,02005156 0,06274197 ! activation of caspase activity GO:0006919 27 27 1,000 0,02005156 0,06263563 ! cell growth GO:0016049 27 27 1,000 0,02005156 0,06252965 ! secretion by cell GO:0032940 75 72 2,000 0,02050669 0,06384094 ! stress-activated protein kinase signaling pathway GO:0031098 28 28 1,000 0,02148255 0,06676616 GO:0007254|JNK cascade, ! regulation of muscle contraction GO:0006937 28 28 1,000 0,02148255 0,06665376 ! keratinocyte differentiation GO:0030216 28 28 1,000 0,02148255 0,06654173 ! histone modification GO:0016570 28 28 1,000 0,02148255 0,06643009 ! developmental growth GO:0048589 28 28 1,000 0,02148255 0,06631881 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,02148255 0,06620791 ! cartilage development GO:0051216 29 28 1,000 0,02148255 0,06609738 ! glycerophospholipid biosynthetic process GO:0046474 30 29 1,000 0,02295484 0,07050961 ! viral reproductive process GO:0022415 29 29 1,000 0,02295484 0,07039229 ! phosphoinositide metabolic process GO:0030384 29 29 1,000 0,02295484 0,07027536 ! leukocyte migration GO:0050900 30 29 1,000 0,02295484 0,07015882 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,02295484 0,07004266 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! covalent chromatin modification GO:0016569 29 29 1,000 0,02295484 0,06992689 ! negative regulation of cell communication GO:0010648 76 76 2,000 0,02362947 0,07186322 ! cellular metal ion homeostasis GO:0006875 77 77 2,000 0,02444838 0,07423125 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,02446769 0,07416769 GO:0043280|positive regulation of caspase activity, ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 1,000 0,02446769 0,07404591 ! skeletal system morphogenesis GO:0048705 31 30 1,000 0,02446769 0,07392452 ! response to temperature stimulus GO:0009266 30 30 1,000 0,02446769 0,07380353 ! regulation of ossification GO:0030278 30 30 1,000 0,02446769 0,07368294 ! vascular process in circulatory system GO:0003018 31 30 1,000 0,02446769 0,07356274 ! immunoglobulin mediated immune response GO:0016064 30 30 1,000 0,02446769 0,07344293 GO:0019724|B cell mediated immunity, ! vesicle organization GO:0016050 30 30 1,000 0,02446769 0,07332351 ! establishment of organelle localization GO:0051656 31 30 1,000 0,02446769 0,07320448 ! metal ion homeostasis GO:0055065 78 78 2,000 0,02528259 0,07551994 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,02602038 0,07759799 ! lipoprotein metabolic process GO:0042157 31 31 1,000 0,02602038 0,07747263 ! glycerolipid biosynthetic process GO:0045017 32 31 1,000 0,02602038 0,07734767 ! nucleoside metabolic process GO:0009116 31 31 1,000 0,02602038 0,07722312 ! regulation of heart contraction GO:0008016 31 31 1,000 0,02602038 0,07709896 ! camera-type eye development GO:0043010 31 31 1,000 0,02602038 0,07697521 ! regulation of intracellular transport GO:0032386 31 31 1,000 0,02602038 0,07685185 ! neuron projection development GO:0031175 85 80 2,000 0,02699683 0,07960824 ! muscle fiber development GO:0048747 32 32 1,000 0,02761217 0,08129269 ! cell maturation GO:0048469 32 32 1,000 0,02761217 0,08116304 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,02761217 0,0810338 ! protein maturation by peptide bond cleavage GO:0051605 32 32 1,000 0,02761217 0,08090497 ! lipid catabolic process GO:0016042 82 81 2,000 0,02787684 0,08155083 ! regulation of neuron differentiation GO:0045664 34 33 1,000 0,02924235 0,08540991 ! regulation of synaptic transmission GO:0050804 33 33 1,000 0,02924235 0,08527477 ! response to metal ion GO:0010038 34 34 1,000 0,03091022 0,0899961 ! regulation of protein catabolic process GO:0042176 35 34 1,000 0,03091022 0,08985415 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 1,000 0,03091022 0,08971265 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 0,03091022 0,08957159 ! secondary metabolic process GO:0019748 34 34 1,000 0,03091022 0,08943098 ! viral reproduction GO:0016032 34 34 1,000 0,03091022 0,0892908 ! regulation of cellular localization GO:0060341 86 85 2,000 0,03154917 0,09099393 ! organophosphate metabolic process GO:0019637 87 86 2,000 0,0325052 0,09360483 GO:0006644|phospholipid metabolic process, ! multicellular organism reproduction GO:0032504 36 35 1,000 0,03261507 0,09377469 GO:0048609|reproductive process in a multicellular organism, ! response to steroid hormone stimulus GO:0048545 35 35 1,000 0,03261507 0,09362863 ! response to inorganic substance GO:0010035 36 36 1,000 0,03435622 0,09847359 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 1,000 0,03435622 0,09832068 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 1,000 0,03435622 0,09816825 ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 0,03435622 0,09801628 ! regulation of transmission of nerve impulse GO:0051969 36 36 1,000 0,03435622 0,09786479 ! gonad development GO:0008406 36 36 1,000 0,03435622 0,09771376 ! male gamete generation GO:0048232 90 88 2,000 0,03446262 0,09786535 GO:0007283|spermatogenesis, ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 2,000 0,03546394 0,10055391 ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 0,03613299 0,10229355 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,03613299 0,10213666 GO:0090046|regulation of transcription regulator activity, ! lymphocyte mediated immunity GO:0002449 37 37 1,000 0,03613299 0,10198025 ! eye development GO:0001654 37 37 1,000 0,03613299 0,10182432 ! adaptive immune response GO:0002250 37 37 1,000 0,03613299 0,10166886 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 2,000 0,03751161 0,10538704 ! DNA replication GO:0006260 91 91 2,000 0,03751161 0,10522664 ! positive regulation of secretion GO:0051047 39 38 1,000 0,0379447 0,10627977 ! cellular hormone metabolic process GO:0034754 39 38 1,000 0,0379447 0,1061185 ! chromosome segregation GO:0007059 38 38 1,000 0,0379447 0,10595771 ! RNA elongation GO:0006354 38 38 1,000 0,0379447 0,10579741 ! axon guidance GO:0007411 39 38 1,000 0,0379447 0,1056376 ! regulation of neurological system process GO:0031644 38 38 1,000 0,0379447 0,10547827 ! positive regulation of protein modification process GO:0031401 39 39 1,000 0,0397907 0,11044315 ! nucleoside monophosphate metabolic process GO:0009123 39 39 1,000 0,0397907 0,11027707 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,0397907 0,11011149 ! developmental maturation GO:0021700 39 39 1,000 0,0397907 0,10994641 ! rRNA transcription GO:0009303 5 5 0,000 0,04005198 0,11050269 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,04005198 0,11033752 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,04005198 0,11017283 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,04005198 0,11000864 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,04005198 0,10984494 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,04005198 0,10968172 ! reproductive cellular process GO:0048610 5 5 0,000 0,04005198 0,10951899 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,04005198 0,10935674 ! water transport GO:0006833 5 5 0,000 0,04005198 0,10919497 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,04005198 0,10903368 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,04005198 0,10887286 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,04005198 0,10871252 ! glycerol metabolic process GO:0006071 5 5 0,000 0,04005198 0,10855265 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,04005198 0,10839324 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,04005198 0,10823431 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,04005198 0,10807584 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,04005198 0,10791783 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,04005198 0,10776029 ! filopodium assembly GO:0046847 7 5 0,000 0,04005198 0,10760321 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,04005198 0,10744658 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,04005198 0,10729041 ! GTP metabolic process GO:0046039 5 5 0,000 0,04005198 0,10713469 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,04005198 0,10697942 ! mRNA stabilization GO:0048255 5 5 0,000 0,04005198 0,1068246 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,04005198 0,10667023 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,04005198 0,1065163 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,04005198 0,10636282 ! social behavior GO:0035176 5 5 0,000 0,04005198 0,10620978 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,04005198 0,10605718 ! memory GO:0007613 5 5 0,000 0,04005198 0,10590502 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,04005198 0,10575329 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,04005198 0,105602 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,04005198 0,10545114 ! response to lipid GO:0033993 5 5 0,000 0,04005198 0,10530071 ! erythrocyte maturation GO:0043249 5 5 0,000 0,04005198 0,10515071 ! hippocampus development GO:0021766 6 5 0,000 0,04005198 0,10500114 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,04005198 0,10485199 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,04005198 0,10470326 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,04005198 0,10455496 ! mechanosensory behavior GO:0007638 5 5 0,000 0,04005198 0,10440707 ! heart looping GO:0001947 5 5 0,000 0,04005198 0,1042596 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,04005198 0,10411255 ! response to interferon-gamma GO:0034341 5 5 0,000 0,04005198 0,10396591 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,04005198 0,10381969 ! endocrine pancreas development GO:0031018 5 5 0,000 0,04005198 0,10367388 ! pH reduction GO:0045851 5 5 0,000 0,04005198 0,10352847 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,04005198 0,10338347 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,04005198 0,10323888 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,04005198 0,10309469 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,04005198 0,10295091 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,04005198 0,10280752 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,04005198 0,10266453 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,04005198 0,10252194 ! melanocyte differentiation GO:0030318 5 5 0,000 0,04005198 0,10237975 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,04005198 0,10223795 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,04005198 0,10209654 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,04005198 0,10195552 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,04005198 0,1018149 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,04005198 0,10167465 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,04005198 0,1015348 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,04005198 0,10139533 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,04005198 0,10125624 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,04005198 0,10111753 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,04005198 0,10097921 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,04005198 0,10084126 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,04005198 0,10070368 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,04005198 0,10056648 ! response to ATP GO:0033198 5 5 0,000 0,04005198 0,10042966 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,04005198 0,10029321 ! regulation of appetite GO:0032098 5 5 0,000 0,04005198 0,10015712 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,04005198 0,10002141 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,04005198 0,09988606 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,04005198 0,09975108 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,04005198 0,09961646 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,04005198 0,09948221 ! receptor clustering GO:0043113 5 5 0,000 0,04005198 0,09934832 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,04005198 0,09921478 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,04005198 0,09908161 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,04005198 0,09894879 ! retinol metabolic process GO:0042572 5 5 0,000 0,04005198 0,09881633 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,04005198 0,09868422 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,04005198 0,09855247 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,04005198 0,09842107 ! parturition GO:0007567 5 5 0,000 0,04005198 0,09829001 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,04005198 0,09815931 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,04005198 0,09802895 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,04005198 0,09789894 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,04005198 0,09776927 ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,04005198 0,09763995 ! oligodendrocyte development GO:0014003 5 5 0,000 0,04005198 0,09751096 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,04005198 0,09738232 ! activated T cell proliferation GO:0050798 5 5 0,000 0,04005198 0,09725402 ! interaction with symbiont GO:0051702 5 5 0,000 0,04005198 0,09712605 ! cellular extravasation GO:0045123 5 5 0,000 0,04005198 0,09699842 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,04005198 0,09687113 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,04005198 0,09674417 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,04005198 0,09661754 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,04005198 0,09649124 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,04005198 0,09636527 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,04005198 0,09623963 ! response to amine stimulus GO:0014075 5 5 0,000 0,04005198 0,09611432 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,04005198 0,09598934 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,04005198 0,09586467 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,04005198 0,09574034 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,04005198 0,09561632 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,04005198 0,09549262 ! neuron recognition GO:0008038 5 5 0,000 0,04005198 0,09536925 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,04005198 0,09524619 ! decidualization GO:0046697 5 5 0,000 0,04005198 0,09512345 ! hair follicle maturation GO:0048820 5 5 0,000 0,04005198 0,09500103 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,04005198 0,09487892 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,04005198 0,09475712 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,04005198 0,09463564 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,04005198 0,09451447 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,04005198 0,09439361 ! postreplication repair GO:0006301 5 5 0,000 0,04005198 0,09427305 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,04005198 0,09415281 GO:0021517|ventral spinal cord development, ! histone methylation GO:0016571 5 5 0,000 0,04005198 0,09403287 ! DNA methylation GO:0006306 5 5 0,000 0,04005198 0,09391323 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,04005198 0,0937939 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,04005198 0,09367487 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,04005198 0,09355615 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,04005198 0,09343772 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,04005198 0,09331959 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,04005198 0,09320177 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,04005198 0,09308424 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,04005198 0,092967 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,04005198 0,09285006 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,04005198 0,09273342 ! sterol catabolic process GO:0016127 5 5 0,000 0,04005198 0,09261706 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,04005198 0,092501 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,04005198 0,09238523 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,04005198 0,09226975 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,04005198 0,09215456 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,04005198 0,09203965 ! zymogen activation GO:0031638 5 5 0,000 0,04005198 0,09192503 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,04005198 0,0918107 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,04005198 0,09169664 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,04005198 0,09158288 ! nucleosome positioning GO:0016584 5 5 0,000 0,04005198 0,09146939 ! regulation of isotype switching GO:0045191 5 5 0,000 0,04005198 0,09135619 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,04005198 0,09124326 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,04005198 0,09113062 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,04005198 0,09101825 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,04005198 0,09090616 ! NADPH regeneration GO:0006740 5 5 0,000 0,04005198 0,09079434 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,04005198 0,0906828 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,04005198 0,09057153 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,04005198 0,09046054 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,04005198 0,09034982 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,04005198 0,09023936 ! sarcomere organization GO:0045214 5 5 0,000 0,04005198 0,09012918 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,04005198 0,09001927 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,04005198 0,08990962 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,04005198 0,08980024 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,04005198 0,08969113 GO:0045622|regulation of T-helper cell differentiation, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,04005198 0,08958228 ! male genitalia development GO:0030539 5 5 0,000 0,04005198 0,0894737 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,04005198 0,08936537 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,04005198 0,08925731 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,04005198 0,08914952 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,04005198 0,08904198 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,04005198 0,0889347 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,04005198 0,08882768 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,04005198 0,08872091 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,04005198 0,0886144 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,04005198 0,08850815 ! ATP catabolic process GO:0006200 5 5 0,000 0,04005198 0,08840215 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,04005198 0,08829641 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,04005198 0,08819092 ! blastocyst formation GO:0001825 5 5 0,000 0,04005198 0,08808568 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,04005198 0,08798069 ! embryonic gut development GO:0048566 5 5 0,000 0,04005198 0,08787595 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,04005198 0,08777146 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,04005198 0,08766722 ! activation of innate immune response GO:0002218 5 5 0,000 0,04005198 0,08756323 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,04005198 0,08745948 ! catecholamine transport GO:0051937 5 5 0,000 0,04005198 0,08735598 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,04005198 0,08725272 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,04005198 0,0871497 ! muscle adaptation GO:0043500 5 5 0,000 0,04005198 0,08704693 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,04005198 0,0869444 ! embryonic heart tube development GO:0035050 5 5 0,000 0,04005198 0,08684212 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,04005198 0,08674007 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,04005198 0,08663826 ! defense response to fungus GO:0050832 5 5 0,000 0,04005198 0,08653669 ! lysogeny GO:0030069 5 5 0,000 0,04005198 0,08643536 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,04005198 0,08633427 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,04005198 0,08623341 ! establishment of cell polarity GO:0030010 5 5 0,000 0,04005198 0,08613279 ! mitochondrion localization GO:0051646 5 5 0,000 0,04005198 0,0860324 ! nucleus localization GO:0051647 5 5 0,000 0,04005198 0,08593225 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,04005198 0,08583232 ! DNA catabolic process GO:0006308 41 40 1,000 0,04167031 0,08919673 ! organelle localization GO:0051640 41 40 1,000 0,04167031 0,08909326 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 1,000 0,04358291 0,0930745 ! phospholipid biosynthetic process GO:0008654 42 41 1,000 0,04358291 0,09296678 ! leukocyte mediated immunity GO:0002443 41 41 1,000 0,04358291 0,0928593 ! regulation of Ras GTPase activity GO:0032318 41 41 1,000 0,04358291 0,09275207 ! endocytosis GO:0006897 99 98 2,000 0,04514672 0,09596932 GO:0010324|membrane invagination, ! posttranscriptional regulation of gene expression GO:0010608 98 98 2,000 0,04514672 0,09585875 ! glycoprotein metabolic process GO:0009100 99 98 2,000 0,04514672 0,09574844 ! regulation of system process GO:0044057 98 98 2,000 0,04514672 0,09563839 ! cytosolic calcium ion homeostasis GO:0051480 42 42 1,000 0,04552783 0,09633501 ! development of primary sexual characteristics GO:0045137 42 42 1,000 0,04552783 0,09622454 ! response to protein stimulus GO:0051789 42 42 1,000 0,04552783 0,09611431 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,04552783 0,09600434 ! anti-apoptosis GO:0006916 100 99 2,000 0,04629624 0,09751311 ! homeostasis of number of cells GO:0048872 44 43 1,000 0,04750446 0,09994375 ! axon extension GO:0048675 7 6 0,000 0,04787119 0,10060047 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,04787119 0,10048589 ! tRNA modification GO:0006400 6 6 0,000 0,04787119 0,10037157 ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,04787119 0,10025751 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,04787119 0,10014371 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,04787119 0,10003017 ! regulation of S phase GO:0033261 6 6 0,000 0,04787119 0,09991688 ! myotube differentiation GO:0014902 6 6 0,000 0,04787119 0,09980386 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,04787119 0,09969108 ! bone remodeling GO:0046849 6 6 0,000 0,04787119 0,09957857 ! N-glycan processing GO:0006491 6 6 0,000 0,04787119 0,0994663 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,04787119 0,09935429 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,04787119 0,09924253 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,04787119 0,09913102 ! RNA methylation GO:0001510 6 6 0,000 0,04787119 0,09901976 ! cartilage condensation GO:0001502 7 6 0,000 0,04787119 0,09890875 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,04787119 0,09879799 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,04787119 0,09868748 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,04787119 0,09857722 ! bile acid metabolic process GO:0008206 6 6 0,000 0,04787119 0,0984672 ! androgen metabolic process GO:0008209 6 6 0,000 0,04787119 0,09835742 ! estrogen metabolic process GO:0008210 6 6 0,000 0,04787119 0,09824789 ! limbic system development GO:0021761 7 6 0,000 0,04787119 0,09813861 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,04787119 0,09802957 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 0,000 0,04787119 0,09792076 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,04787119 0,0978122 ! pathogenesis GO:0009405 6 6 0,000 0,04787119 0,09770389 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,04787119 0,09759581 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,04787119 0,09748797 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,04787119 0,09738036 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,04787119 0,097273 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,04787119 0,09716587 ! arginine metabolic process GO:0006525 6 6 0,000 0,04787119 0,09705898 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,04787119 0,09695232 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,04787119 0,09684589 ! glutamate catabolic process GO:0006538 7 6 0,000 0,04787119 0,0967397 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,04787119 0,09663374 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,04787119 0,09652802 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,04787119 0,09642252 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,04787119 0,09631726 ! V(D)J recombination GO:0033151 6 6 0,000 0,04787119 0,09621222 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,04787119 0,09610742 ! lipid digestion GO:0044241 6 6 0,000 0,04787119 0,09600284 ! asymmetric protein localization GO:0008105 6 6 0,000 0,04787119 0,09589849 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,04787119 0,09579436 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,04787119 0,09569046 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,04787119 0,09558679 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,04787119 0,09548334 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,04787119 0,09538012 ! ruffle organization GO:0031529 6 6 0,000 0,04787119 0,09527712 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,04787119 0,09517434 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,04787119 0,09507178 ! neutral amino acid transport GO:0015804 6 6 0,000 0,04787119 0,09496944 ! L-amino acid transport GO:0015807 6 6 0,000 0,04787119 0,09486732 ! bone mineralization GO:0030282 6 6 0,000 0,04787119 0,09476542 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,04787119 0,09466374 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,04787119 0,09456228 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,04787119 0,09446104 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,04787119 0,09436001 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,04787119 0,0942592 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,04787119 0,0941586 ! regulation of organ growth GO:0046620 6 6 0,000 0,04787119 0,09405822 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,04787119 0,09395805 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,04787119 0,09385809 ! response to dsRNA GO:0043331 6 6 0,000 0,04787119 0,09375835 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,04787119 0,09365882 ! genitalia development GO:0048806 6 6 0,000 0,04787119 0,0935595 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,04787119 0,09346039 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,04787119 0,09336149 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,04787119 0,0932628 ! multicellular organismal aging GO:0010259 6 6 0,000 0,04787119 0,09316432 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,04787119 0,09306604 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,04787119 0,09296798 ! erythrocyte development GO:0048821 6 6 0,000 0,04787119 0,09287011 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,04787119 0,09277246 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,04787119 0,09267501 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,04787119 0,09257776 ! ribosome assembly GO:0042255 6 6 0,000 0,04787119 0,09248072 ! diencephalon development GO:0021536 6 6 0,000 0,04787119 0,09238388 ! fucose catabolic process GO:0019317 6 6 0,000 0,04787119 0,09228725 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,04787119 0,09219081 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,04787119 0,09209458 ! regulation of lipid transport GO:0032368 6 6 0,000 0,04787119 0,09199855 ! regulation of cell division GO:0051302 6 6 0,000 0,04787119 0,09190272 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,04787119 0,09180708 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,04787119 0,09171165 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,04787119 0,09161642 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,04787119 0,09152138 ! neuroblast proliferation GO:0007405 6 6 0,000 0,04787119 0,09142654 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,04787119 0,09133189 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,04787119 0,09123744 ! regulation of glucose transport GO:0010827 6 6 0,000 0,04787119 0,09114319 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,04787119 0,09104913 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,04787119 0,09095527 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,04787119 0,09086159 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,04787119 0,09076812 ! lymph node development GO:0048535 6 6 0,000 0,04787119 0,09067483 ! organic cation transport GO:0015695 6 6 0,000 0,04787119 0,09058173 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,04787119 0,09048883 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,04787119 0,09039612 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,04787119 0,09030359 ! sperm-egg recognition GO:0035036 7 6 0,000 0,04787119 0,09021126 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,04787119 0,09011911 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,04787119 0,09002715 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,04787119 0,08993538 ! alditol metabolic process GO:0019400 6 6 0,000 0,04787119 0,0898438 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,04787119 0,0897524 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,04787119 0,08966119 ! maternal placenta development GO:0001893 6 6 0,000 0,04787119 0,08957016 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,04787119 0,08947932 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 0,04951217 0,09245282 ! protein import into nucleus GO:0006606 44 44 1,000 0,04951217 0,09235925 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,04951217 0,09226586 ! vitamin metabolic process GO:0006766 44 44 1,000 0,04951217 0,09217266 ! regulation of actin cytoskeleton organization GO:0032956 46 45 1,000 0,05155035 0,09587012 ! regulation of DNA binding GO:0051101 47 45 1,000 0,05155035 0,09577348 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 0,05155035 0,09567703 ! steroid biosynthetic process GO:0006694 46 45 1,000 0,05155035 0,09558077 ! nuclear import GO:0051170 45 45 1,000 0,05155035 0,09548471 ! protein processing GO:0016485 45 45 1,000 0,05155035 0,09538884 ! regulation of actin filament-based process GO:0032970 47 46 1,000 0,05361837 0,09911601 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 0,05361837 0,09901669 ! positive regulation of ligase activity GO:0051351 47 46 1,000 0,05361837 0,09891758 ! respiratory burst GO:0045730 7 7 0,000 0,05562784 0,10252211 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,05562784 0,1024197 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,05562784 0,10231748 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,05562784 0,10221547 ! regulation of chemokine production GO:0032642 7 7 0,000 0,05562784 0,10211366 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,05562784 0,10201205 GO:0000725|recombinational repair, ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,05562784 0,10191065 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,05562784 0,10180945 GO:0043241|protein complex disassembly, ! gene silencing by RNA GO:0031047 7 7 0,000 0,05562784 0,10170845 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,05562784 0,10160765 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,05562784 0,10150704 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,05562784 0,10140664 ! startle response GO:0001964 7 7 0,000 0,05562784 0,10130644 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,05562784 0,10120643 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,05562784 0,10110662 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,05562784 0,10100701 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,05562784 0,10090759 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,05562784 0,10080837 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,05562784 0,10070935 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,05562784 0,10061052 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,05562784 0,10051188 ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,05562784 0,10041343 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,05562784 0,10031518 ! protein targeting to ER GO:0045047 8 7 0,000 0,05562784 0,10021712 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,05562784 0,10011925 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,05562784 0,10002158 ! endoderm development GO:0007492 7 7 0,000 0,05562784 0,09992409 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,05562784 0,09982679 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,05562784 0,09972968 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,05562784 0,09963276 ! response to hexose stimulus GO:0009746 7 7 0,000 0,05562784 0,09953603 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,05562784 0,09943949 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,05562784 0,09934313 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,05562784 0,09924697 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,05562784 0,09915098 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,05562784 0,09905518 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,05562784 0,09895957 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,05562784 0,09886414 ! myofibril assembly GO:0030239 7 7 0,000 0,05562784 0,0987689 GO:0055002|striated muscle cell development, ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,05562784 0,09867384 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,05562784 0,09857896 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,05562784 0,09848426 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,05562784 0,09838975 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,05562784 0,09829541 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,05562784 0,09820126 GO:0019827|stem cell maintenance, ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,05562784 0,09810729 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,05562784 0,09801349 ! axon cargo transport GO:0008088 7 7 0,000 0,05562784 0,09791988 ! eating behavior GO:0042755 7 7 0,000 0,05562784 0,09782645 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,05562784 0,09773319 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,05562784 0,09764011 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,05562784 0,09754721 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,05562784 0,09745448 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,05562784 0,09736193 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,05562784 0,09726956 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,05562784 0,09717736 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,05562784 0,09708534 ! intracellular lipid transport GO:0032365 7 7 0,000 0,05562784 0,09699349 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,05562784 0,09690181 ! platelet activation GO:0030168 8 7 0,000 0,05562784 0,09681031 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,05562784 0,09671898 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,05562784 0,09662782 ! natural killer cell activation GO:0030101 7 7 0,000 0,05562784 0,09653683 ! NADP metabolic process GO:0006739 7 7 0,000 0,05562784 0,09644602 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,05562784 0,09635537 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,05562784 0,0962649 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,05562784 0,09617459 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,05562784 0,09608446 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,05562784 0,09599449 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,05562784 0,09590469 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,05562784 0,09581506 GO:0001953|negative regulation of cell-matrix adhesion, ! regulation of ATPase activity GO:0043462 7 7 0,000 0,05562784 0,0957256 ! cell-cell recognition GO:0009988 8 7 0,000 0,05562784 0,0956363 ! hormone catabolic process GO:0042447 7 7 0,000 0,05562784 0,09554717 ! dopamine metabolic process GO:0042417 7 7 0,000 0,05562784 0,09545821 ! oxygen transport GO:0015671 7 7 0,000 0,05562784 0,09536941 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,05562784 0,09528078 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,05562784 0,09519231 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,05562784 0,095104 ! regulation of axon extension GO:0030516 7 7 0,000 0,05562784 0,09501586 ! cell killing GO:0001906 7 7 0,000 0,05562784 0,09492788 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,05562784 0,09484007 ! adult feeding behavior GO:0008343 7 7 0,000 0,05562784 0,09475242 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,05562784 0,09466493 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,05562784 0,0945776 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,05562784 0,09449043 ! response to cold GO:0009409 7 7 0,000 0,05562784 0,09440342 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 1,000 0,05571565 0,09446545 ! rhythmic process GO:0048511 47 47 1,000 0,05571565 0,09437863 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 0,05784159 0,09788985 ! glycerophospholipid metabolic process GO:0006650 49 48 1,000 0,05784159 0,09780004 ! protein localization in nucleus GO:0034504 48 48 1,000 0,05784159 0,0977104 ! cell cycle arrest GO:0007050 49 49 1,000 0,0599956 0,1012563 ! cellular lipid catabolic process GO:0044242 50 49 1,000 0,0599956 0,10116366 ! regulation of ligase activity GO:0051340 50 49 1,000 0,0599956 0,10107119 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,0621771 0,10465059 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,06332242 0,10648104 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,06332242 0,10638398 ! positive regulation of translation GO:0045727 8 8 0,000 0,06332242 0,10628709 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,06332242 0,10619038 ! superoxide anion generation GO:0042554 8 8 0,000 0,06332242 0,10609384 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,06332242 0,10599748 ! cGMP metabolic process GO:0046068 8 8 0,000 0,06332242 0,10590129 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,06332242 0,10580528 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,06332242 0,10570944 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,06332242 0,10561378 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,06332242 0,10551829 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,06332242 0,10542297 ! zinc ion transport GO:0006829 8 8 0,000 0,06332242 0,10532782 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,06332242 0,10523284 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,06332242 0,10513804 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,06332242 0,10504341 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,06332242 0,10494894 ! lipid localization GO:0010876 8 8 0,000 0,06332242 0,10485465 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,06332242 0,10476052 ! response to cAMP GO:0051591 8 8 0,000 0,06332242 0,10466657 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,06332242 0,10457278 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,06332242 0,10447916 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,06332242 0,10438571 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,06332242 0,10429243 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,06332242 0,10419931 ! sensory perception of taste GO:0050909 8 8 0,000 0,06332242 0,10410635 ! organelle fusion GO:0048284 8 8 0,000 0,06332242 0,10401357 ! pancreas development GO:0031016 8 8 0,000 0,06332242 0,10392095 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,06332242 0,10382849 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,06332242 0,1037362 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,06332242 0,10364407 ! sperm motility GO:0030317 8 8 0,000 0,06332242 0,10355211 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,06332242 0,1034603 ! glycine metabolic process GO:0006544 8 8 0,000 0,06332242 0,10336867 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,06332242 0,10327719 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,06332242 0,10318587 GO:0031114|regulation of microtubule depolymerization, ! polyamine metabolic process GO:0006595 8 8 0,000 0,06332242 0,10309472 ! Golgi organization GO:0007030 8 8 0,000 0,06332242 0,10300373 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,06332242 0,1029129 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,06332242 0,10282222 ! fructose metabolic process GO:0006000 8 8 0,000 0,06332242 0,10273171 ! mannose metabolic process GO:0006013 9 8 0,000 0,06332242 0,10264136 ! NAD metabolic process GO:0019674 8 8 0,000 0,06332242 0,10255116 ! plasma membrane fusion GO:0045026 8 8 0,000 0,06332242 0,10246113 ! response to fungus GO:0009620 8 8 0,000 0,06332242 0,10237125 ! stem cell differentiation GO:0048863 8 8 0,000 0,06332242 0,10228153 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,06332242 0,10219196 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,06332242 0,10210256 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,06332242 0,10201331 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,06332242 0,10192421 ! regulation of vasodilation GO:0042312 8 8 0,000 0,06332242 0,10183527 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,06332242 0,10174649 ! muscle cell development GO:0055001 8 8 0,000 0,06332242 0,10165786 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,06332242 0,10156939 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,06332242 0,10148106 ! sensory perception of pain GO:0019233 8 8 0,000 0,06332242 0,1013929 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,06332242 0,10130488 ! mRNA cleavage GO:0006379 8 8 0,000 0,06332242 0,10121702 ! chromatin silencing GO:0006342 8 8 0,000 0,06332242 0,10112931 ! tissue regeneration GO:0042246 8 8 0,000 0,06332242 0,10104175 ! salivary gland development GO:0007431 8 8 0,000 0,06332242 0,10095435 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,06332242 0,10086709 ! cofactor transport GO:0051181 8 8 0,000 0,06332242 0,10077999 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,06332242 0,10069303 ! acid secretion GO:0046717 8 8 0,000 0,06332242 0,10060623 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,06332242 0,10051957 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,06332242 0,10043307 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,06332242 0,10034671 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,06332242 0,1002605 ! regulation of RNA stability GO:0043487 8 8 0,000 0,06332242 0,10017444 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,06332242 0,10008853 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,06332242 0,10000276 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,06332242 0,09991714 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,06332242 0,09983167 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,06332242 0,09974635 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,06332242 0,09966116 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,06332242 0,09957613 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,06332242 0,09949124 ! actin filament polymerization GO:0030041 9 8 0,000 0,06332242 0,09940649 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,06332242 0,09932189 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,06332242 0,09923744 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,06332242 0,09915312 ! protein maturation GO:0051604 51 51 1,000 0,06438552 0,10073218 ! regulation of GTPase activity GO:0043087 53 52 1,000 0,0666203 0,10414013 ! regulation of T cell activation GO:0050863 53 53 1,000 0,06888087 0,10758259 ! regulation of protein transport GO:0051223 53 53 1,000 0,06888087 0,10749149 GO:0070201|regulation of establishment of protein localization, ! lactation GO:0007595 10 9 0,000 0,07095542 0,11063522 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,07095542 0,1105417 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,07095542 0,11044834 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,07095542 0,11035513 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,07095542 0,11026209 ! viral genome replication GO:0019079 9 9 0,000 0,07095542 0,11016919 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,07095542 0,11007646 ! copper ion transport GO:0006825 9 9 0,000 0,07095542 0,10998388 ! lipid phosphorylation GO:0046834 9 9 0,000 0,07095542 0,10989146 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,07095542 0,10979919 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,07095542 0,10970708 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,07095542 0,10961512 ! RNA polyadenylation GO:0043631 9 9 0,000 0,07095542 0,10952331 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,07095542 0,10943166 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,07095542 0,10934016 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,07095542 0,10924882 ! phospholipid efflux GO:0033700 9 9 0,000 0,07095542 0,10915762 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,07095542 0,10906658 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,07095542 0,1089757 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,07095542 0,10888496 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,07095542 0,10879437 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,07095542 0,10870394 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,07095542 0,10861365 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,07095542 0,10852351 ! methionine metabolic process GO:0006555 9 9 0,000 0,07095542 0,10843353 ! glutamine metabolic process GO:0006541 9 9 0,000 0,07095542 0,10834369 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,07095542 0,108254 ! central nervous system neuron development GO:0021954 10 9 0,000 0,07095542 0,10816446 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,07095542 0,10807507 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,07095542 0,10798583 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,07095542 0,10789673 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,07095542 0,10780778 ! L-glutamate transport GO:0015813 9 9 0,000 0,07095542 0,10771897 GO:0015800|acidic amino acid transport, ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,07095542 0,10763032 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,07095542 0,1075418 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,07095542 0,10745344 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,07095542 0,10736522 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,07095542 0,10727714 ! positive regulation of protein import into nucleus GO:0042307 9 9 0,000 0,07095542 0,10718921 ! DNA replication initiation GO:0006270 9 9 0,000 0,07095542 0,10710142 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,07095542 0,10701378 GO:0006692|prostanoid metabolic process, ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,07095542 0,10692627 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,07095542 0,10683892 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,07095542 0,1067517 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,07095542 0,10666463 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,07095542 0,1065777 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,07095542 0,10649091 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,07095542 0,10640426 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,07095542 0,10631775 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,07095542 0,10623138 ! collagen catabolic process GO:0030574 9 9 0,000 0,07095542 0,10614516 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,07095542 0,10605907 ! purine base metabolic process GO:0006144 9 9 0,000 0,07095542 0,10597312 ! gas transport GO:0015669 9 9 0,000 0,07095542 0,10588732 ! cholesterol efflux GO:0033344 9 9 0,000 0,07095542 0,10580165 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,07095542 0,10571612 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,07095542 0,10563072 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,07095542 0,10554547 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,07095542 0,10546035 ! actin filament-based movement GO:0030048 9 9 0,000 0,07095542 0,10537537 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,07095542 0,10529053 ! response to virus GO:0009615 54 54 1,000 0,0711667 0,10551909 ! sulfur metabolic process GO:0006790 55 54 1,000 0,0711667 0,10543427 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 1,000 0,07817026 0,1157171 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,07852731 0,11615236 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,07852731 0,11605921 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,07852731 0,11596622 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,07852731 0,11587337 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,07852731 0,11578067 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,07852731 0,11568812 ! neuron maturation GO:0042551 10 10 0,000 0,07852731 0,11559572 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,07852731 0,11550346 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,07852731 0,11541135 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,07852731 0,11531939 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,07852731 0,11522758 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,07852731 0,11513591 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,07852731 0,11504439 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,07852731 0,11495301 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,07852731 0,11486178 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,07852731 0,11477069 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,07852731 0,11467975 ! phototransduction GO:0007602 11 10 0,000 0,07852731 0,11458895 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,07852731 0,11449829 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,07852731 0,11440778 ! fat cell differentiation GO:0045444 10 10 0,000 0,07852731 0,11431741 ! myoblast differentiation GO:0045445 10 10 0,000 0,07852731 0,11422718 ! centrosome cycle GO:0007098 10 10 0,000 0,07852731 0,1141371 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,07852731 0,11404715 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,07852731 0,11395735 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,07852731 0,11386769 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,07852731 0,11377817 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,07852731 0,1136888 ! protein polyubiquitination GO:0000209 10 10 0,000 0,07852731 0,11359956 ! glutamate metabolic process GO:0006536 11 10 0,000 0,07852731 0,11351046 ! plasma membrane organization GO:0007009 10 10 0,000 0,07852731 0,1134215 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,07852731 0,11333268 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,07852731 0,11324401 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,07852731 0,11315546 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,07852731 0,11306706 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,07852731 0,1129788 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,07852731 0,11289067 ! exocrine system development GO:0035272 10 10 0,000 0,07852731 0,11280268 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,07852731 0,11271483 ! embryo implantation GO:0007566 11 10 0,000 0,07852731 0,11262711 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,07852731 0,11253953 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,07852731 0,11245209 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,07852731 0,11236478 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,07852731 0,11227761 ! protein export from nucleus GO:0006611 10 10 0,000 0,07852731 0,11219057 ! negative regulation of immune response GO:0050777 10 10 0,000 0,07852731 0,11210367 ! cytolysis GO:0019835 10 10 0,000 0,07852731 0,1120169 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,07852731 0,11193027 GO:0030501|positive regulation of bone mineralization, ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,07852731 0,11184377 ! histone deacetylation GO:0016575 10 10 0,000 0,07852731 0,1117574 ! mRNA splice site selection GO:0006376 11 10 0,000 0,07852731 0,11167117 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,07852731 0,11158507 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,07852731 0,11149911 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,07852731 0,11141327 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,07852731 0,11132757 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,07852731 0,111242 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,07852731 0,11115656 ! regulation of epidermis development GO:0045682 10 10 0,000 0,07852731 0,11107125 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,07852731 0,11098607 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,07852731 0,11090103 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,07852731 0,11081611 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,07852731 0,11073132 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,07852731 0,11064667 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,07852731 0,11056214 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,07852731 0,11047774 ! protein stabilization GO:0050821 10 10 0,000 0,07852731 0,11039347 ! protein localization in organelle GO:0033365 59 59 1,000 0,08295576 0,11653008 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,0853819 0,1198468 ! protein secretion GO:0009306 11 11 0,000 0,08603859 0,12067665 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,08603859 0,12058488 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,08603859 0,12049325 ! negative regulation of defense response GO:0031348 11 11 0,000 0,08603859 0,12040176 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,08603859 0,12031041 ! microtubule-based transport GO:0010970 11 11 0,000 0,08603859 0,1202192 ! endothelial cell migration GO:0043542 11 11 0,000 0,08603859 0,12012812 ! peroxisomal transport GO:0043574 11 11 0,000 0,08603859 0,12003718 ! protein amino acid methylation GO:0006479 11 11 0,000 0,08603859 0,11994639 GO:0008213|protein amino acid alkylation, ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 0,000 0,08603859 0,11985572 GO:0032388|positive regulation of intracellular transport, ! heart contraction GO:0060047 11 11 0,000 0,08603859 0,1197652 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,08603859 0,11967481 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,08603859 0,11958456 ! T cell proliferation GO:0042098 11 11 0,000 0,08603859 0,11949444 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,08603859 0,11940446 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,08603859 0,11931461 ! digestive system process GO:0022600 11 11 0,000 0,08603859 0,1192249 ! mitotic spindle organization GO:0007052 11 11 0,000 0,08603859 0,11913533 ! fucose metabolic process GO:0006004 11 11 0,000 0,08603859 0,11904589 ! membrane budding GO:0006900 11 11 0,000 0,08603859 0,11895658 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,08603859 0,11886741 ! monoamine transport GO:0015844 11 11 0,000 0,08603859 0,11877837 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,08603859 0,11868946 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,08603859 0,11860069 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,08603859 0,11851205 ! intermediate filament-based process GO:0045103 11 11 0,000 0,08603859 0,11842354 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,08603859 0,11833517 GO:0060415|muscle tissue morphogenesis, ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,08603859 0,11824692 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,08603859 0,11815881 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,08603859 0,11807083 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,08603859 0,11798298 ! vitamin transport GO:0051180 11 11 0,000 0,08603859 0,11789526 ! muscle maintenance GO:0046716 12 11 0,000 0,08603859 0,11780767 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,08603859 0,11772021 ! steroid catabolic process GO:0006706 11 11 0,000 0,08603859 0,11763288 ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,08603859 0,11754568 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,08603859 0,11745861 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,08603859 0,11737167 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,08782962 0,11972633 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 0,08782962 0,11963784 ! regulation of cellular component biogenesis GO:0044087 63 62 1,000 0,09029844 0,12290991 ! protein import GO:0017038 62 62 1,000 0,09029844 0,1228192 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,09029844 0,12272863 ! regulation of secretion GO:0051046 65 63 1,000 0,09278785 0,12601916 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,09278785 0,12592636 ! glucose metabolic process GO:0006006 63 63 1,000 0,09278785 0,1258337 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,09348972 0,12669232 ! translational initiation GO:0006413 12 12 0,000 0,09348972 0,12659924 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,09348972 0,12650629 ! initiation of viral infection GO:0019059 12 12 0,000 0,09348972 0,12641347 ! iron ion transport GO:0006826 13 12 0,000 0,09348972 0,12632079 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,09348972 0,12622825 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,09348972 0,12613584 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,09348972 0,12604357 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,09348972 0,12595143 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,09348972 0,12585943 ! collagen metabolic process GO:0032963 12 12 0,000 0,09348972 0,12576756 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,09348972 0,12567583 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,09348972 0,12558423 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,09348972 0,12549276 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,09348972 0,12540143 GO:0042744|hydrogen peroxide catabolic process, ! actomyosin structure organization GO:0031032 12 12 0,000 0,09348972 0,12531023 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,09348972 0,12521916 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,09348972 0,12512822 ! retinoid metabolic process GO:0001523 12 12 0,000 0,09348972 0,12503742 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,09348972 0,12494674 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,09348972 0,1248562 ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,09348972 0,12476579 ! acute-phase response GO:0006953 12 12 0,000 0,09348972 0,12467551 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,09348972 0,12458537 ! vacuolar transport GO:0007034 12 12 0,000 0,09348972 0,12449535 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,09348972 0,12440546 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,09348972 0,1243157 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,09348972 0,12422607 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,09348972 0,12413657 GO:0051693|actin filament capping, ! regulation of insulin secretion GO:0050796 12 12 0,000 0,09348972 0,1240472 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,09348972 0,12395796 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,09348972 0,12386884 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,09348972 0,12377986 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,09348972 0,123691 ! cell fate determination GO:0001709 12 12 0,000 0,09348972 0,12360227 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,09348972 0,12351366 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,09348972 0,12342519 ! detection of light stimulus GO:0009583 13 12 0,000 0,09348972 0,12333684 ! synaptogenesis GO:0007416 12 12 0,000 0,09348972 0,12324861 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,09348972 0,12316052 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,09348972 0,12307254 ! heme biosynthetic process GO:0006783 12 12 0,000 0,09348972 0,1229847 ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,09348972 0,12289698 ! neural tube closure GO:0001843 13 12 0,000 0,09348972 0,12280938 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,09348972 0,12272191 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 0,09529737 0,12500573 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,09529737 0,12491682 ! protein amino acid glycosylation GO:0006486 66 66 1,000 0,10037486 0,13147894 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 1,000 0,10037486 0,13138556 ! negative regulation of protein metabolic process GO:0051248 66 66 1,000 0,10037486 0,13129231 ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,10088119 0,13186101 ! phenol metabolic process GO:0018958 13 13 0,000 0,10088119 0,13176756 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,10088119 0,13167424 ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,10088119 0,13158105 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,10088119 0,131488 ! keratinization GO:0031424 13 13 0,000 0,10088119 0,13139507 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,10088119 0,13130228 ! vasculogenesis GO:0001570 13 13 0,000 0,10088119 0,13120962 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,10088119 0,13111709 ! regulation of innate immune response GO:0045088 13 13 0,000 0,10088119 0,13102469 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,10088119 0,13093242 ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,10088119 0,13084027 ! autophagy GO:0006914 13 13 0,000 0,10088119 0,13074826 ! receptor metabolic process GO:0043112 14 13 0,000 0,10088119 0,13065638 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,10088119 0,13056463 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,10088119 0,130473 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,10088119 0,13038151 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,10088119 0,13029014 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,10088119 0,1301989 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,10088119 0,13010779 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,10088119 0,1300168 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,10088119 0,12992595 ! vasodilation GO:0042311 14 13 0,000 0,10088119 0,12983522 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,10088119 0,12974461 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,10088119 0,12965413 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,10088119 0,12956378 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,10088119 0,12947356 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,10088119 0,12938346 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,10088119 0,12929348 ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,10088119 0,12920363 ! cell-cell junction organization GO:0045216 13 13 0,000 0,10088119 0,12911391 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,10088119 0,12902431 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,10088119 0,12893483 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,10088119 0,12884548 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,10088119 0,12875625 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,10088119 0,12866715 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,10088119 0,12857817 ! blastocyst development GO:0001824 13 13 0,000 0,10088119 0,12848931 ! telomere organization GO:0032200 13 13 0,000 0,10088119 0,12840057 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,10088119 0,12831196 ! regulation of amine transport GO:0051952 13 13 0,000 0,10088119 0,12822347 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,10088119 0,1281351 ! muscle contraction GO:0006936 67 67 1,000 0,10294188 0,13066246 ! regulation of translation GO:0006417 69 69 1,000 0,1081302 0,13715344 ! sensory perception of sound GO:0007605 71 69 1,000 0,1081302 0,13705912 GO:0050954|sensory perception of mechanical stimulus, ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,1081302 0,13696492 ! neuron fate commitment GO:0048663 14 14 0,000 0,10821345 0,13697623 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,10821345 0,13688222 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,10821345 0,13678833 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,10821345 0,13669458 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,10821345 0,13660095 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,10821345 0,13650745 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,10821345 0,13641408 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,10821345 0,13632084 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,10821345 0,13622773 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,10821345 0,13613474 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,10821345 0,13604188 ! vesicle docking GO:0048278 14 14 0,000 0,10821345 0,13594914 ! superoxide metabolic process GO:0006801 15 14 0,000 0,10821345 0,13585653 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,10821345 0,13576405 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,10821345 0,13567169 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,10821345 0,13557946 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,10821345 0,13548736 ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,10821345 0,13539538 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,10821345 0,13530352 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! lysosome organization GO:0007040 14 14 0,000 0,10821345 0,13521179 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,10821345 0,13512018 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,10821345 0,1350287 GO:0045936|negative regulation of phosphate metabolic process, ! primary neural tube formation GO:0014020 15 14 0,000 0,10821345 0,13493734 ! peptide cross-linking GO:0018149 14 14 0,000 0,10821345 0,13484611 ! regulation of behavior GO:0050795 14 14 0,000 0,10821345 0,13475499 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,10821345 0,134664 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,10821345 0,13457314 ! formation of primary germ layer GO:0001704 14 14 0,000 0,10821345 0,13448239 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,10821345 0,13439177 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,10821345 0,13430127 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,10821345 0,1342109 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,10821345 0,13412064 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,10821345 0,1340305 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,10821345 0,13394049 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,10821345 0,1338506 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,10821345 0,13376083 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,10821345 0,13367117 ! positive regulation of transport GO:0051050 71 70 1,000 0,11075059 0,13671355 ! regulation of cell activation GO:0050865 71 71 1,000 0,11338787 0,1398754 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,11548698 0,14236957 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,11548698 0,1422744 ! positive regulation of ossification GO:0045778 15 15 0,000 0,11548698 0,14217936 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,11548698 0,14208445 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,11548698 0,14198966 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,11548698 0,141895 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,11548698 0,14180047 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,11548698 0,14170606 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,11548698 0,14161178 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,11548698 0,14151762 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,11548698 0,14142359 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,11548698 0,14132968 ! heme metabolic process GO:0042168 15 15 0,000 0,11548698 0,1412359 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,11548698 0,14114224 ! chromosome condensation GO:0030261 15 15 0,000 0,11548698 0,14104871 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,11548698 0,1409553 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,11548698 0,14086201 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,11548698 0,14076885 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,11548698 0,14067581 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,11548698 0,1405829 ! phospholipid transport GO:0015914 15 15 0,000 0,11548698 0,1404901 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,11548698 0,14039743 ! glutathione metabolic process GO:0006749 16 15 0,000 0,11548698 0,14030488 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,11548698 0,14021245 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,11548698 0,14012015 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,11548698 0,14002796 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,11548698 0,1399359 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,11548698 0,13984396 GO:0090048|negative regulation of transcription regulator activity, ! protein homooligomerization GO:0051260 15 15 0,000 0,11548698 0,13975214 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,11548698 0,13966044 ! muscle system process GO:0003012 72 72 1,000 0,11604162 0,14023915 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,12270224 0,14819149 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,12270224 0,14809445 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,12270224 0,14799753 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,12270224 0,14790073 ! circadian rhythm GO:0007623 16 16 0,000 0,12270224 0,14780407 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,12270224 0,14770752 ! vacuole organization GO:0007033 16 16 0,000 0,12270224 0,14761111 ! vesicle targeting GO:0006903 17 16 0,000 0,12270224 0,14751482 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,12270224 0,14741866 ! iron ion homeostasis GO:0055072 16 16 0,000 0,12270224 0,14732262 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,12270224 0,14722671 ! fatty acid transport GO:0015908 16 16 0,000 0,12270224 0,14713092 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,12270224 0,14703525 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,12270224 0,14693971 ! cofactor catabolic process GO:0051187 16 16 0,000 0,12270224 0,1468443 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,12270224 0,14674901 ! polyol metabolic process GO:0019751 16 16 0,000 0,12270224 0,14665384 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,12270224 0,14655879 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,12270224 0,14646387 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,12270224 0,14636907 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,12270224 0,1462744 GO:0001841|neural tube formation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,12270224 0,14617984 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,12270224 0,14608541 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,12985968 0,15450703 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,12985968 0,15440734 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,12985968 0,15430779 ! leukocyte adhesion GO:0007159 17 17 0,000 0,12985968 0,15420837 ! sensory perception of smell GO:0007608 17 17 0,000 0,12985968 0,15410907 ! tissue remodeling GO:0048771 17 17 0,000 0,12985968 0,1540099 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,12985968 0,15391086 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,12985968 0,15381194 ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,12985968 0,15371316 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,12985968 0,1536145 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,12985968 0,15351596 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,12985968 0,15341755 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,12985968 0,15331927 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,12985968 0,15322112 ! adult locomotory behavior GO:0008344 17 17 0,000 0,12985968 0,15312309 ! embryonic organ development GO:0048568 17 17 0,000 0,12985968 0,15302518 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,12985968 0,1529274 ! gene silencing GO:0016458 17 17 0,000 0,12985968 0,15282975 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,1322861 0,15558602 ! nuclear transport GO:0051169 79 79 1,000 0,13504335 0,15872761 GO:0006913|nucleocytoplasmic transport, ! mRNA export from nucleus GO:0006406 18 18 0,000 0,13695976 0,16087752 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,13695976 0,16077505 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,13695976 0,16067271 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,13695976 0,1605705 ! membrane docking GO:0022406 18 18 0,000 0,13695976 0,16046843 ! response to calcium ion GO:0051592 18 18 0,000 0,13695976 0,16036648 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,13695976 0,16026466 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,13695976 0,16016297 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,13695976 0,1600614 ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,13695976 0,15995997 ! ceramide metabolic process GO:0006672 18 18 0,000 0,13695976 0,15985867 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,13695976 0,15975749 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! hexose biosynthetic process GO:0019319 18 18 0,000 0,13695976 0,15965644 ! BMP signaling pathway GO:0030509 18 18 0,000 0,13695976 0,15955552 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,13695976 0,15945473 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,13695976 0,15935406 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,13695976 0,15925352 ! glycoprotein biosynthetic process GO:0009101 80 80 1,000 0,13781378 0,16014552 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,14400293 0,16723214 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,14400293 0,16712683 GO:0006956|complement activation, ! feeding behavior GO:0007631 19 19 0,000 0,14400293 0,16702165 ! peroxisome organization GO:0007031 19 19 0,000 0,14400293 0,1669166 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,14400293 0,16681169 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,14400293 0,16670691 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,14400293 0,16660226 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,14400293 0,16649774 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,14400293 0,16639336 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,14400293 0,1662891 ! regulation of cell shape GO:0008360 21 19 0,000 0,14400293 0,16618497 ! placenta development GO:0001890 19 19 0,000 0,14400293 0,16608098 ! vesicle localization GO:0051648 20 19 0,000 0,14400293 0,16597711 ! cellular amino acid derivative metabolic process GO:0006575 87 84 1,000 0,14901958 0,17165193 ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,15098964 0,17381256 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,15098964 0,17370407 ! negative regulation of binding GO:0051100 21 20 0,000 0,15098964 0,1735957 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,15098964 0,17348748 ! neural tube development GO:0021915 21 20 0,000 0,15098964 0,17337939 ! nucleus organization GO:0006997 20 20 0,000 0,15098964 0,17327143 ! phagocytosis GO:0006909 21 20 0,000 0,15098964 0,1731636 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,15098964 0,17305592 ! protein targeting to membrane GO:0006612 22 20 0,000 0,15098964 0,17294836 ! chromatin remodeling GO:0006338 20 20 0,000 0,15098964 0,17284094 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,15098964 0,17273365 ! lipid oxidation GO:0034440 20 20 0,000 0,15098964 0,1726265 GO:0019395|fatty acid oxidation, ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,15098964 0,17251947 ! RNA modification GO:0009451 20 20 0,000 0,15098964 0,17241259 ! single fertilization GO:0007338 21 20 0,000 0,15098964 0,17230583 ! regulation of B cell activation GO:0050864 20 20 0,000 0,15098964 0,1721992 ! positive regulation of cell differentiation GO:0045597 87 85 1,000 0,1518502 0,17307354 ! hexose metabolic process GO:0019318 87 86 1,000 0,15469174 0,17620326 ! mRNA catabolic process GO:0006402 21 21 0,000 0,15792034 0,17976973 ! Notch signaling pathway GO:0007219 22 21 0,000 0,15792034 0,17965876 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,15792034 0,17954793 ! organic anion transport GO:0015711 21 21 0,000 0,15792034 0,17943723 ! cholesterol transport GO:0030301 21 21 0,000 0,15792034 0,17932667 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,15792034 0,17921625 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,15792034 0,17910596 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,15792034 0,17899581 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,15792034 0,17888579 ! purine nucleotide biosynthetic process GO:0006164 88 88 1,000 0,16040622 0,18159009 ! RNA export from nucleus GO:0006405 22 22 0,000 0,16479546 0,18644447 ! regulation of ion transport GO:0043269 22 22 0,000 0,16479546 0,18633008 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,16479546 0,18621584 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,16479546 0,18610174 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,16479546 0,18598778 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,16479546 0,18587395 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,16479546 0,18576027 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,16479546 0,18564672 ! biopolymer methylation GO:0043414 22 22 0,000 0,16479546 0,18553332 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,16479546 0,18542005 ! detection of external stimulus GO:0009581 23 22 0,000 0,16479546 0,18530692 ! neuron migration GO:0001764 22 22 0,000 0,16479546 0,18519392 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,16479546 0,18508107 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,16479546 0,18496835 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,16479546 0,18485577 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,16479546 0,18474333 ! aerobic respiration GO:0009060 22 22 0,000 0,16479546 0,18463103 ! cytokine production GO:0001816 22 22 0,000 0,16479546 0,18451886 ! regulation of Ras protein signal transduction GO:0046578 90 90 1,000 0,16616024 0,18593401 ! viral infectious cycle GO:0019058 23 23 0,000 0,17161545 0,19192189 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,17161545 0,1918055 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,17161545 0,19168925 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,17161545 0,19157315 ! lipid homeostasis GO:0055088 23 23 0,000 0,17161545 0,19145718 ! cell projection assembly GO:0030031 25 23 0,000 0,17161545 0,19134136 ! fatty acid metabolic process GO:0006631 93 92 1,000 0,17195107 0,19159965 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,17838073 0,19864392 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,17838073 0,19852396 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,17838073 0,19840415 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,17838073 0,19828449 ! fertilization GO:0009566 25 24 0,000 0,17838073 0,19816497 ! maintenance of protein location GO:0045185 25 24 0,000 0,17838073 0,19804559 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,17838073 0,19792636 ! glucan metabolic process GO:0044042 25 24 0,000 0,17838073 0,19780727 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,18509174 0,20512572 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,18509174 0,20500245 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,18509174 0,20487932 ! cellular component disassembly GO:0022411 26 25 0,000 0,18509174 0,20475635 ! endosome transport GO:0016197 25 25 0,000 0,18509174 0,20463352 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,18509174 0,20451083 ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,18509174 0,2043883 ! gastrulation GO:0007369 25 25 0,000 0,18509174 0,20426591 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,18509174 0,20414367 ! regulation of endocytosis GO:0030100 25 25 0,000 0,18509174 0,20402157 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,18509174 0,20389962 ! positive regulation of defense response GO:0031349 26 26 0,000 0,1917489 0,21110706 ! glycolysis GO:0006096 26 26 0,000 0,1917489 0,21098103 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,1917489 0,21085515 ! cellular defense response GO:0006968 26 26 0,000 0,1917489 0,21072941 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,1917489 0,21060383 ! regulation of protein secretion GO:0050708 26 26 0,000 0,1917489 0,2104784 ! maintenance of location in cell GO:0051651 27 26 0,000 0,1917489 0,21035311 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 1,000 0,19543091 0,21426482 ! response to other organism GO:0051707 101 100 1,000 0,19543091 0,21413743 ! chloride transport GO:0006821 27 27 0,000 0,19835265 0,2172097 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,19835265 0,21708072 ! energy reserve metabolic process GO:0006112 28 27 0,000 0,19835265 0,21695189 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,19835265 0,21682321 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,19835265 0,21669468 ! peptide metabolic process GO:0006518 29 27 0,000 0,19835265 0,21656631 ! inner ear development GO:0048839 27 27 0,000 0,19835265 0,21643809 ! defense response to bacterium GO:0042742 27 27 0,000 0,19835265 0,21631002 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,19835265 0,2161821 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,19835265 0,21605433 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,20490339 0,22305786 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! neuromuscular process GO:0050905 28 28 0,000 0,20490339 0,22292618 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,20490339 0,22279466 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,20490339 0,2226633 ! antigen processing and presentation GO:0019882 29 29 0,000 0,21140155 0,22958931 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,21140155 0,2294541 ! tRNA processing GO:0008033 29 29 0,000 0,21140155 0,22931905 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,21140155 0,22918415 ! adult behavior GO:0030534 30 29 0,000 0,21140155 0,22904942 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,21140155 0,22891484 ! positive regulation of protein transport GO:0051222 29 29 0,000 0,21140155 0,22878042 ! transition metal ion transport GO:0000041 31 30 0,000 0,21784755 0,23561798 ! RNA catabolic process GO:0006401 30 30 0,000 0,21784755 0,23547978 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,21784755 0,23534175 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,21784755 0,23520388 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,21784755 0,23506618 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,21784755 0,23492863 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,21784755 0,23479125 ! regulation of inflammatory response GO:0050727 30 30 0,000 0,21784755 0,23465402 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,21784755 0,23451696 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,21784755 0,23438005 ! regulation of translational initiation GO:0006446 31 31 0,000 0,22424179 0,24111879 ! membrane fusion GO:0006944 31 31 0,000 0,22424179 0,2409782 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,22424179 0,24083777 ! ion transmembrane transport GO:0034220 31 31 0,000 0,22424179 0,2406975 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! digestion GO:0007586 31 31 0,000 0,22424179 0,2405574 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,22424179 0,24041746 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,22424179 0,24027768 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,22424179 0,24013807 ! cell redox homeostasis GO:0045454 32 32 0,000 0,23058468 0,2467872 ! glucose catabolic process GO:0006007 32 32 0,000 0,23058468 0,24664397 ! lipid modification GO:0030258 32 32 0,000 0,23058468 0,24650091 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,23058468 0,24635801 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,23058468 0,24621527 ! nuclear export GO:0051168 32 32 0,000 0,23058468 0,24607271 ! maintenance of location GO:0051235 33 32 0,000 0,23058468 0,2459303 ! amino acid transport GO:0006865 33 33 0,000 0,23687663 0,25249486 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,23687663 0,25234891 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,23687663 0,25220313 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,23687663 0,25205752 ! regulation of actin filament length GO:0030832 34 34 0,000 0,24311803 0,25854964 ! muscle cell differentiation GO:0042692 35 34 0,000 0,24311803 0,25840054 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,24311803 0,2582516 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,24311803 0,25810284 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,24311803 0,25795425 ! detection of stimulus GO:0051606 36 34 0,000 0,24311803 0,25780583 ! acute inflammatory response GO:0002526 35 35 0,000 0,2493093 0,26421911 ! regulation of cellular component size GO:0032535 35 35 0,000 0,2493093 0,26406726 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,2493093 0,26391558 ! mesoderm development GO:0007498 35 35 0,000 0,2493093 0,26376408 ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,2493093 0,26361276 ! inorganic anion transport GO:0015698 35 35 0,000 0,2493093 0,2634616 ! regulation of immune effector process GO:0002697 35 35 0,000 0,2493093 0,26331062 ! hydrogen transport GO:0006818 36 36 0,000 0,25545081 0,26964252 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,25545081 0,26948818 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,25545081 0,26933401 GO:0035113|embryonic appendage morphogenesis, ! heterocycle catabolic process GO:0046700 36 36 0,000 0,25545081 0,26918002 ! activation of immune response GO:0002253 36 36 0,000 0,25545081 0,2690262 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,26154297 0,27528481 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,26154297 0,27512768 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,26154297 0,27497074 ! neurotransmitter transport GO:0006836 40 38 0,000 0,26758617 0,2811638 ! exocytosis GO:0006887 40 38 0,000 0,26758617 0,2810036 ! hexose catabolic process GO:0019320 38 38 0,000 0,26758617 0,28084357 ! response to unfolded protein GO:0006986 39 39 0,000 0,27358079 0,28697177 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,27358079 0,28680853 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,27358079 0,28664548 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,27358079 0,28648261 ! limb development GO:0060173 39 39 0,000 0,27358079 0,28631993 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! myeloid cell differentiation GO:0030099 42 40 0,000 0,27952721 0,29237721 ! amine catabolic process GO:0009310 42 41 0,000 0,28542582 0,29837764 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,28542582 0,29820849 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,29127699 0,30414929 ! protein ubiquitination GO:0016567 43 42 0,000 0,29127699 0,30397706 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,29127699 0,30380503 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! one-carbon metabolic process GO:0006730 42 42 0,000 0,29127699 0,3036332 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,2970811 0,30950846 ! alcohol catabolic process GO:0046164 43 43 0,000 0,2970811 0,30933359 ! mRNA transport GO:0051028 44 44 0,000 0,30283851 0,31515041 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,30283851 0,31497256 ! amine biosynthetic process GO:0009309 46 45 0,000 0,30854961 0,32073149 ! homophilic cell adhesion GO:0007156 45 45 0,000 0,30854961 0,32055069 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,31421475 0,32625227 ! amine transport GO:0015837 47 47 0,000 0,31983429 0,33190011 ! calcium ion transport GO:0006816 48 48 0,000 0,3254086 0,33749469 ! divalent metal ion transport GO:0070838 49 49 0,000 0,33093804 0,34303645 ! response to bacterium GO:0009617 50 49 0,000 0,33093804 0,34284363 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,33093804 0,34265102 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,33093804 0,34245863 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,33642296 0,34793912 ! chromatin assembly GO:0031497 50 50 0,000 0,33642296 0,34774398 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,33642296 0,34754906 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 0,000 0,33642296 0,34735435 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,33642296 0,34715986 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,34186371 0,35257684 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,34186371 0,35237965 ! positive regulation of immune response GO:0050778 51 51 0,000 0,34186371 0,35218268 ! rRNA metabolic process GO:0016072 51 51 0,000 0,34186371 0,35198593 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,34186371 0,3517894 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,34186371 0,35159309 ! RNA localization GO:0006403 52 52 0,000 0,34726064 0,35694443 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,34726064 0,35674546 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 0,000 0,34726064 0,35654672 ! sodium ion transport GO:0006814 53 53 0,000 0,35261409 0,36184175 ! tRNA metabolic process GO:0006399 53 53 0,000 0,35261409 0,36164039 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,35261409 0,36143925 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,35261409 0,36123834 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,35261409 0,36103765 ! nucleosome organization GO:0034728 55 55 0,000 0,36319196 0,37166174 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,36319196 0,37145549 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,36319196 0,37124947 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,36841706 0,37638173 ! ATP metabolic process GO:0046034 57 57 0,000 0,37360003 0,3814653 ! innate immune response GO:0045087 58 58 0,000 0,37874123 0,3865006 ! carboxylic acid transport GO:0046942 59 59 0,000 0,38384098 0,39148806 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,38384098 0,39127153 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,38384098 0,39105524 ! potassium ion transport GO:0006813 60 60 0,000 0,38889961 0,39599005 ! protein polymerization GO:0051258 65 60 0,000 0,38889961 0,39577139 ! cellular respiration GO:0045333 62 61 0,000 0,39391744 0,40065665 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,39391744 0,40043566 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,3988948 0,40527184 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,3988948 0,40504855 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,3988948 0,40482551 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,40383201 0,40961057 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,40383201 0,40938526 ! anion transport GO:0006820 65 65 0,000 0,41358725 0,41904414 ! DNA packaging GO:0006323 66 66 0,000 0,4184059 0,42369344 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,4184059 0,42346077 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,42318566 0,42806321 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,42792683 0,43262158 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,42792683 0,4323844 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,43729463 0,44160768 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,44192187 0,44603615 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,44192187 0,44579202 ! ribosome biogenesis GO:0042254 71 71 0,000 0,44192187 0,44554815 ! regulation of cytokine production GO:0001817 72 72 0,000 0,44651174 0,44992954 ! electron transport chain GO:0022900 75 74 0,000 0,45558051 0,45881688 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,45558051 0,4585663 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,46006002 0,46282239 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,46006002 0,46256989 ! microtubule-based movement GO:0007018 82 78 0,000 0,47328244 0,47560498 ! regulation of immune response GO:0050776 78 78 0,000 0,47328244 0,4753458 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,49461652 0,49650232 ! ncRNA processing GO:0034470 83 83 0,000 0,49461652 0,49623204 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,50291046 0,50427855 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,50291046 0,50400434 ! visual perception GO:0007601 93 92 0,000 0,5309 0,5317656 GO:0050953|sensory perception of light stimulus, ! energy derivation by oxidation of organic compounds GO:0015980 94 92 0,000 0,5309 0,53147676 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,5309 0,53118822 ! cofactor metabolic process GO:0051186 95 94 0,000 0,53860865 0,53860865