pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6429-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 4,000 1,342E-09 3,279E-06 ! apoptotic mitochondrial changes GO:0008637 42 20 4,000 4,343E-08 5,305E-05 ! induction of positive chemotaxis GO:0050930 17 9 3,000 7,513E-08 6,118E-05 ! induction of apoptosis by intracellular signals GO:0008629 95 45 5,000 1,004E-07 6,131E-05 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 5,000 1,15E-07 5,618E-05 ! negative regulation of phosphorylation GO:0042326 52 24 4,000 1,171E-07 4,769E-05 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 4,000 1,798E-07 6,276E-05 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 4,000 1,798E-07 5,491E-05 GO:0045936|negative regulation of phosphate metabolic process, ! peptidyl-tyrosine modification GO:0018212 57 28 4,000 2,665E-07 7,234E-05 ! regulation of positive chemotaxis GO:0050926 22 12 3,000 2,917E-07 7,126E-05 GO:0050927|positive regulation of positive chemotaxis, ! release of cytochrome c from mitochondria GO:0001836 31 14 3,000 5,853E-07 1,3E-04 ! interphase of mitotic cell cycle GO:0051329 224 98 6,000 6,615E-07 1,347E-04 ! regulation of sensory perception GO:0051931 8 5 2,000 1,226E-06 2,304E-04 GO:0051930|regulation of sensory perception of pain, ! myoblast cell fate commitment GO:0048625 18 6 2,000 2,443E-06 4,262E-04 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 4,000 2,456E-06 4E-04 ! cell structure disassembly during apoptosis GO:0006921 32 21 3,000 3,405E-06 5,199E-04 ! microtubule-based transport GO:0010970 59 22 3,000 4,145E-06 5,957E-04 ! positive regulation of locomotion GO:0040017 44 22 3,000 4,145E-06 5,626E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 2,000 4,259E-06 5,476E-04 ! regulation of chemotaxis GO:0050920 45 23 3,000 4,998E-06 6,105E-04 ! regulation of lipid kinase activity GO:0043550 17 8 2,000 6,789E-06 7,898E-04 ! positive regulation of insulin secretion GO:0032024 17 8 2,000 6,789E-06 7,539E-04 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 6,789E-06 7,211E-04 ! regulation of behavior GO:0050795 48 25 3,000 7,084E-06 7,211E-04 ! fat cell differentiation GO:0045444 57 28 3,000 1,133E-05 1,107E-03 ! regulation of smooth muscle cell migration GO:0014910 27 10 2,000 1,444E-05 1,357E-03 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 2,000 1,444E-05 1,307E-03 ! negative regulation of BMP signaling pathway GO:0030514 19 10 2,000 1,444E-05 1,26E-03 ! response to peptide hormone stimulus GO:0043434 129 64 4,000 1,787E-05 1,505E-03 ! chondrocyte differentiation GO:0002062 27 11 2,000 1,978E-05 1,611E-03 ! positive regulation of peptide secretion GO:0002793 24 11 2,000 1,978E-05 1,559E-03 ! thymus development GO:0048538 29 11 2,000 1,978E-05 1,51E-03 ! negative regulation of glucose import GO:0046325 18 11 2,000 1,978E-05 1,465E-03 GO:0010829|negative regulation of glucose transport, ! negative regulation of cell growth GO:0030308 142 67 4,000 2,236E-05 1,607E-03 ! negative regulation of cell size GO:0045792 144 69 4,000 2,581E-05 1,802E-03 ! negative regulation of protein kinase activity GO:0006469 144 69 4,000 2,581E-05 1,752E-03 ! regulation of hormone metabolic process GO:0032350 28 12 2,000 2,628E-05 1,735E-03 ! negative regulation of mast cell proliferation GO:0070667 24 12 2,000 2,628E-05 1,69E-03 GO:0042130|negative regulation of T cell proliferation, ! negative regulation of kinase activity GO:0033673 145 70 4,000 2,769E-05 1,734E-03 ! spleen development GO:0048536 24 13 2,000 3,404E-05 2,079E-03 ! androgen receptor signaling pathway GO:0030521 81 37 3,000 3,529E-05 2,103E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 4,000 3,626E-05 2,109E-03 ! negative regulation of transferase activity GO:0051348 155 74 4,000 3,626E-05 2,06E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 2,000 4,316E-05 2,396E-03 ! carbohydrate homeostasis GO:0033500 59 39 3,000 4,361E-05 2,368E-03 GO:0042593|glucose homeostasis, ! learning GO:0007612 82 40 3,000 4,827E-05 2,563E-03 ! mesenchymal cell development GO:0014031 94 41 3,000 5,328E-05 2,769E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! negative regulation of bone remodeling GO:0046851 34 15 2,000 5,375E-05 2,736E-03 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 5,375E-05 2,68E-03 ! epithelial to mesenchymal transition GO:0001837 30 15 2,000 5,375E-05 2,626E-03 ! positive regulation of phosphorylation GO:0042327 149 81 4,000 5,607E-05 2,686E-03 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 4,000 6,302E-05 2,961E-03 GO:0045937|positive regulation of phosphate metabolic process, ! startle response GO:0001964 28 16 2,000 6,591E-05 3,038E-03 ! axon cargo transport GO:0008088 46 16 2,000 6,591E-05 2,982E-03 ! negative regulation of tissue remodeling GO:0034104 37 16 2,000 6,591E-05 2,928E-03 ! negative regulation of leukocyte proliferation GO:0070664 32 16 2,000 6,591E-05 2,875E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! response to nutrient GO:0007584 135 84 4,000 6,674E-05 2,861E-03 ! positive regulation of response to external stimulus GO:0032103 88 44 3,000 7,058E-05 2,973E-03 ! negative regulation of growth GO:0045926 168 85 4,000 7,063E-05 2,925E-03 ! mitochondrion organization GO:0007005 159 87 4,000 7,892E-05 3,213E-03 ! myoblast differentiation GO:0045445 50 17 2,000 7,974E-05 3,194E-03 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 2,000 7,974E-05 3,142E-03 ! neutrophil chemotaxis GO:0030593 29 17 2,000 7,974E-05 3,092E-03 ! negative regulation of homeostatic process GO:0032845 36 17 2,000 7,974E-05 3,044E-03 ! negative regulation of cell migration GO:0030336 122 46 3,000 8,419E-05 3,164E-03 ! pigmentation GO:0043473 103 46 3,000 8,419E-05 3,116E-03 ! positive regulation of protein modification process GO:0031401 156 90 4,000 9,274E-05 3,382E-03 ! epidermis morphogenesis GO:0048730 43 18 2,000 9,534E-05 3,425E-03 ! response to retinoic acid GO:0032526 31 18 2,000 9,534E-05 3,376E-03 ! regulation of BMP signaling pathway GO:0030510 33 18 2,000 9,534E-05 3,327E-03 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 2,000 9,534E-05 3,28E-03 ! cellular component disassembly GO:0022411 89 48 3,000 9,961E-05 3,38E-03 ! positive regulation of MAP kinase activity GO:0043406 174 93 4,000 1,084E-04 3,626E-03 ! positive regulation of hormone secretion GO:0046887 35 19 2,000 1,128E-04 3,724E-03 ! response to vitamin A GO:0033189 32 19 2,000 1,128E-04 3,674E-03 ! activation of caspase activity GO:0006919 95 50 3,000 1,17E-04 3,76E-03 ! response to vitamin GO:0033273 36 20 2,000 1,322E-04 4,195E-03 ! response to alkaloid GO:0043279 38 20 2,000 1,322E-04 4,141E-03 ! pancreas development GO:0031016 40 20 2,000 1,322E-04 4,089E-03 ! regulation of glucose import GO:0046324 30 20 2,000 1,322E-04 4,038E-03 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 41 20 2,000 1,322E-04 3,988E-03 ! positive regulation of growth GO:0045927 96 53 3,000 1,47E-04 4,38E-03 ! positive regulation of inflammatory response GO:0050729 41 21 2,000 1,537E-04 4,523E-03 ! regulation of angiogenesis GO:0045765 125 54 3,000 1,581E-04 4,599E-03 ! negative regulation of cell motion GO:0051271 142 55 3,000 1,699E-04 4,883E-03 ! glutamate signaling pathway GO:0007215 48 22 2,000 1,773E-04 5,036E-03 ! inactivation of MAPK activity GO:0000188 45 22 2,000 1,773E-04 4,979E-03 ! apoptotic nuclear changes GO:0030262 34 22 2,000 1,773E-04 4,922E-03 ! skeletal muscle fiber development GO:0048741 130 56 3,000 1,822E-04 5,003E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 1,952E-04 5,3E-03 ! regulation of bone remodeling GO:0046850 143 57 3,000 1,952E-04 5,241E-03 ! positive regulation of caspase activity GO:0043280 108 57 3,000 1,952E-04 5,184E-03 GO:0010952|positive regulation of peptidase activity, ! muscle fiber development GO:0048747 131 57 3,000 1,952E-04 5,129E-03 ! regulation of cell-matrix adhesion GO:0001952 81 23 2,000 2,031E-04 5,279E-03 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 47 23 2,000 2,031E-04 5,224E-03 ! activation of pro-apoptotic gene products GO:0008633 51 23 2,000 2,031E-04 5,169E-03 ! positive regulation of cell migration GO:0030335 137 58 3,000 2,089E-04 5,261E-03 ! regulation of tissue remodeling GO:0034103 146 58 3,000 2,089E-04 5,207E-03 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 2,000 2,313E-04 5,708E-03 ! response to corticosteroid stimulus GO:0031960 46 24 2,000 2,313E-04 5,651E-03 ! positive regulation of muscle development GO:0048636 15 5 1,000 2,469E-04 5,973E-03 GO:0045844|positive regulation of striated muscle development, ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,469E-04 5,914E-03 ! 2-oxoglutarate metabolic process GO:0006103 10 5 1,000 2,469E-04 5,857E-03 ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 2,469E-04 5,8E-03 ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 1,000 2,469E-04 5,745E-03 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 1,000 2,469E-04 5,691E-03 ! positive regulation of glycolysis GO:0045821 13 5 1,000 2,469E-04 5,638E-03 ! parathyroid gland development GO:0060017 14 5 1,000 2,469E-04 5,586E-03 ! epithelial cell proliferation GO:0050673 9 5 1,000 2,469E-04 5,534E-03 ! negative regulation of survival gene product expression GO:0008634 9 5 1,000 2,469E-04 5,484E-03 ! valine metabolic process GO:0006573 12 5 1,000 2,469E-04 5,435E-03 ! virus-infected cell apoptosis GO:0006926 7 5 1,000 2,469E-04 5,386E-03 ! peptidyl-threonine phosphorylation GO:0018107 20 5 1,000 2,469E-04 5,338E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 2,469E-04 5,292E-03 ! meiotic chromosome segregation GO:0045132 10 5 1,000 2,469E-04 5,246E-03 ! B cell homeostasis GO:0001782 13 5 1,000 2,469E-04 5,2E-03 ! regulation of mitochondrial depolarization GO:0051900 14 5 1,000 2,469E-04 5,156E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 2,469E-04 5,112E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 2,469E-04 5,069E-03 ! stem cell division GO:0017145 11 5 1,000 2,469E-04 5,027E-03 GO:0048103|somatic stem cell division, ! regulation of insulin secretion GO:0050796 42 25 2,000 2,619E-04 5,287E-03 ! protein tetramerization GO:0051262 57 25 2,000 2,619E-04 5,244E-03 ! regulation of homeostatic process GO:0032844 148 62 3,000 2,704E-04 5,371E-03 ! positive regulation of cell motion GO:0051272 157 65 3,000 3,244E-04 6,391E-03 ! insulin receptor signaling pathway GO:0008286 66 27 2,000 3,306E-04 6,461E-03 ! regulation of endothelial cell proliferation GO:0001936 60 27 2,000 3,306E-04 6,41E-03 ! regulation of chromosome organization GO:0033044 49 27 2,000 3,306E-04 6,36E-03 ! negative regulation of lymphocyte activation GO:0051250 55 27 2,000 3,306E-04 6,31E-03 ! steroid hormone receptor signaling pathway GO:0030518 146 66 3,000 3,44E-04 6,514E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 2,000 3,689E-04 6,933E-03 ! negative regulation of protein modification process GO:0031400 66 28 2,000 3,689E-04 6,88E-03 ! establishment of spindle localization GO:0051293 16 6 1,000 3,692E-04 6,832E-03 GO:0051653|spindle localization, ! neural nucleus development GO:0048857 19 6 1,000 3,692E-04 6,781E-03 ! enucleate erythrocyte differentiation GO:0043353 14 6 1,000 3,692E-04 6,73E-03 ! regulation of myeloid cell apoptosis GO:0033032 14 6 1,000 3,692E-04 6,681E-03 ! negative regulation of osteoblast differentiation GO:0045668 17 6 1,000 3,692E-04 6,631E-03 ! negative regulation of B cell activation GO:0050869 14 6 1,000 3,692E-04 6,583E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 3,000 4,078E-04 7,219E-03 ! regulation of peptide secretion GO:0002791 52 29 2,000 4,1E-04 7,205E-03 ! positive regulation of multicellular organism growth GO:0040018 55 30 2,000 4,539E-04 7,92E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 3,000 4,548E-04 7,88E-03 ! negative regulation of leukocyte activation GO:0002695 60 31 2,000 5,006E-04 8,613E-03 ! sleep GO:0030431 16 7 1,000 5,151E-04 8,8E-03 ! mRNA stabilization GO:0048255 18 7 1,000 5,151E-04 8,739E-03 GO:0043489|RNA stabilization, ! oxaloacetate metabolic process GO:0006107 13 7 1,000 5,151E-04 8,679E-03 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 5,151E-04 8,62E-03 ! organ growth GO:0035265 15 7 1,000 5,151E-04 8,561E-03 ! male sex determination GO:0030238 15 7 1,000 5,151E-04 8,503E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 5,151E-04 8,446E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 5,151E-04 8,39E-03 ! peptidyl-threonine modification GO:0018210 26 7 1,000 5,151E-04 8,334E-03 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 5,151E-04 8,279E-03 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 1,000 5,151E-04 8,225E-03 ! regulation of caspase activity GO:0043281 136 74 3,000 5,323E-04 8,445E-03 ! spindle organization GO:0007051 50 32 2,000 5,504E-04 8,675E-03 ! response to mechanical stimulus GO:0009612 60 32 2,000 5,504E-04 8,619E-03 ! phosphoinositide-mediated signaling GO:0048015 141 75 3,000 5,601E-04 8,716E-03 ! learning or memory GO:0007611 161 76 3,000 5,89E-04 9,107E-03 ! leukocyte chemotaxis GO:0030595 55 33 2,000 6,032E-04 9,268E-03 GO:0060326|cell chemotaxis, ! regulation of endopeptidase activity GO:0052548 141 77 3,000 6,188E-04 9,449E-03 ! response to hydrogen peroxide GO:0042542 56 34 2,000 6,592E-04 0,01000213 ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 6,592E-04 9,94E-03 ! protein oligomerization GO:0051259 149 79 3,000 6,817E-04 0,01021787 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 6,846E-04 0,01019771 ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 1,000 6,846E-04 0,0101359 ! succinate metabolic process GO:0006105 17 8 1,000 6,846E-04 0,01007484 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 6,846E-04 0,01001451 ! T-helper 1 type immune response GO:0042088 12 8 1,000 6,846E-04 9,955E-03 ! pigment granule organization GO:0048753 17 8 1,000 6,846E-04 9,896E-03 ! regulation of pigmentation during development GO:0048070 25 8 1,000 6,846E-04 9,838E-03 ! melanin metabolic process GO:0006582 17 8 1,000 6,846E-04 9,78E-03 ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 6,846E-04 9,723E-03 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 6,846E-04 9,667E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 6,846E-04 9,612E-03 ! response to UV-B GO:0010224 17 8 1,000 6,846E-04 9,557E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 6,846E-04 9,502E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 6,846E-04 9,449E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 1,000 6,846E-04 9,396E-03 ! regulation of synaptic plasticity GO:0048167 78 35 2,000 7,183E-04 9,804E-03 ! muscle cell differentiation GO:0042692 178 81 3,000 7,491E-04 0,01016659 ! regulation of peptidase activity GO:0052547 150 82 3,000 7,844E-04 0,01058774 ! response to drug GO:0042493 149 83 3,000 8,21E-04 0,01101987 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 2,000 8,465E-04 0,01130086 ! negative regulation of cell activation GO:0050866 69 37 2,000 8,465E-04 0,01123944 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 8,773E-04 0,01158474 ! DNA synthesis during DNA repair GO:0000731 18 9 1,000 8,773E-04 0,01152246 ! regulation of glycolysis GO:0006110 20 9 1,000 8,773E-04 0,01146084 ! middle ear morphogenesis GO:0042474 14 9 1,000 8,773E-04 0,01139988 ! T cell selection GO:0045058 27 9 1,000 8,773E-04 0,01133956 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 1,000 8,773E-04 0,01127988 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 1,000 8,773E-04 0,01122082 ! response to amine stimulus GO:0014075 13 9 1,000 8,773E-04 0,01116238 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of mitochondrial membrane potential GO:0051881 19 9 1,000 8,773E-04 0,01110455 ! S phase GO:0051320 10 9 1,000 8,773E-04 0,01104731 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 16 9 1,000 8,773E-04 0,01099065 ! regulation of telomere maintenance GO:0032204 17 9 1,000 8,773E-04 0,01093458 ! cellular response to hormone stimulus GO:0032870 182 85 3,000 8,976E-04 0,01113105 ! regulation of protein stability GO:0031647 77 38 2,000 9,157E-04 0,01129845 ! cellular response to insulin stimulus GO:0032869 85 38 2,000 9,157E-04 0,01124167 ! nucleus organization GO:0006997 73 40 2,000 1,065E-03 0,0130043 ! regulation of neurological system process GO:0031644 175 89 3,000 1,066E-03 0,01295305 ! regulation of developmental growth GO:0048638 16 10 1,000 1,093E-03 0,01321857 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 1,000 1,093E-03 0,01315346 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 1,000 1,093E-03 0,01308898 ! SMAD protein nuclear translocation GO:0007184 21 10 1,000 1,093E-03 0,01302513 ! lung alveolus development GO:0048286 26 10 1,000 1,093E-03 0,0129619 ! phosphagen metabolic process GO:0006599 17 10 1,000 1,093E-03 0,01289929 GO:0006600|creatine metabolic process, ! B cell proliferation GO:0042100 19 10 1,000 1,093E-03 0,01283727 ! motor axon guidance GO:0008045 22 10 1,000 1,093E-03 0,01277585 ! regulation of bone resorption GO:0045124 25 10 1,000 1,093E-03 0,01271501 ! protein heterooligomerization GO:0051291 17 10 1,000 1,093E-03 0,01265475 ! alpha-beta T cell differentiation GO:0046632 24 10 1,000 1,093E-03 0,01259506 ! response to dsRNA GO:0043331 23 10 1,000 1,093E-03 0,01253593 ! regulation of DNA replication initiation GO:0030174 14 10 1,000 1,093E-03 0,01247735 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 1,000 1,093E-03 0,01241931 GO:0043470|regulation of carbohydrate catabolic process, ! response to nicotine GO:0035094 20 10 1,000 1,093E-03 0,01236182 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 1,000 1,093E-03 0,01230485 ! response to inorganic substance GO:0010035 173 90 3,000 1,111E-03 0,01245009 ! regulation of hormone secretion GO:0046883 69 41 2,000 1,144E-03 0,01276673 ! multicellular organismal metabolic process GO:0044236 64 41 2,000 1,144E-03 0,0127087 ! gland development GO:0048732 220 91 3,000 1,158E-03 0,01279606 ! regulation of cell adhesion GO:0030155 241 92 3,000 1,206E-03 0,01326594 ! regulation of T cell differentiation GO:0045580 78 42 2,000 1,228E-03 0,01345275 ! regulation of membrane potential GO:0042391 179 94 3,000 1,306E-03 0,01423827 ! regulation of T cell proliferation GO:0042129 80 43 2,000 1,315E-03 0,0142807 ! detection of mechanical stimulus GO:0050982 22 11 1,000 1,331E-03 0,01439283 ! blood vessel remodeling GO:0001974 30 11 1,000 1,331E-03 0,01432942 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 1,331E-03 0,01426658 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 23 11 1,000 1,331E-03 0,01420428 ! behavioral fear response GO:0001662 27 11 1,000 1,331E-03 0,01414252 GO:0002209|behavioral defense response, ! negative regulation of ossification GO:0030279 27 11 1,000 1,331E-03 0,0140813 ! alpha-beta T cell activation GO:0046631 26 11 1,000 1,331E-03 0,0140206 ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 1,331E-03 0,01396043 ! oocyte development GO:0048599 20 11 1,000 1,331E-03 0,01390077 ! T cell receptor signaling pathway GO:0050852 29 11 1,000 1,331E-03 0,01384161 ! regulation of embryonic development GO:0045995 35 11 1,000 1,331E-03 0,01378296 ! response to reactive oxygen species GO:0000302 75 44 2,000 1,406E-03 0,01449641 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 2,000 1,406E-03 0,0144355 ! regulation of DNA metabolic process GO:0051052 188 97 3,000 1,466E-03 0,0149871 ! positive regulation of cellular catabolic process GO:0031331 34 12 1,000 1,593E-03 0,0162104 ! virus-host interaction GO:0019048 30 12 1,000 1,593E-03 0,01614313 ! regulation of B cell proliferation GO:0030888 22 12 1,000 1,593E-03 0,01607643 ! oligodendrocyte differentiation GO:0048709 17 12 1,000 1,593E-03 0,01601027 ! focal adhesion formation GO:0048041 37 12 1,000 1,593E-03 0,01594465 ! T cell homeostasis GO:0043029 28 12 1,000 1,593E-03 0,01587957 ! regulation of leukocyte migration GO:0002685 29 12 1,000 1,593E-03 0,01581502 ! oocyte differentiation GO:0009994 21 12 1,000 1,593E-03 0,01575099 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 1,593E-03 0,01568748 ! glycolysis GO:0006096 71 46 2,000 1,6E-03 0,01569925 ! leukocyte migration GO:0050900 75 46 2,000 1,6E-03 0,01563646 ! skeletal muscle tissue development GO:0007519 223 100 3,000 1,64E-03 0,01596388 GO:0060538|skeletal muscle organ development, ! response to insulin stimulus GO:0032868 98 47 2,000 1,703E-03 0,01650943 ! positive regulation of cell cycle GO:0045787 96 48 2,000 1,81E-03 0,01747633 ! positive regulation of defense response GO:0031349 88 48 2,000 1,81E-03 0,01740753 ! regulation of inflammatory response GO:0050727 84 48 2,000 1,81E-03 0,01733926 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 1,876E-03 0,01790132 ! indolalkylamine metabolic process GO:0006586 19 13 1,000 1,876E-03 0,01783167 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 1,000 1,876E-03 0,01776255 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 35 13 1,000 1,876E-03 0,01769397 ! protein homotetramerization GO:0051289 24 13 1,000 1,876E-03 0,01762592 ! gland morphogenesis GO:0022612 31 13 1,000 1,876E-03 0,01755839 ! regulation of mRNA stability GO:0043488 32 13 1,000 1,876E-03 0,01749137 ! digestive tract morphogenesis GO:0048546 31 13 1,000 1,876E-03 0,01742486 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! regulation of lymphocyte differentiation GO:0045619 92 49 2,000 1,921E-03 0,01777522 ! regulation of mast cell proliferation GO:0070666 89 49 2,000 1,921E-03 0,01770815 ! induction of apoptosis by extracellular signals GO:0008624 99 50 2,000 2,036E-03 0,01869906 ! regulation of ossification GO:0030278 123 50 2,000 2,036E-03 0,01862902 ! negative regulation of immune system process GO:0002683 101 51 2,000 2,155E-03 0,01964745 ! rRNA transcription GO:0009303 28 14 1,000 2,181E-03 0,01981024 ! hair follicle morphogenesis GO:0031069 27 14 1,000 2,181E-03 0,01973687 ! fear response GO:0042596 34 14 1,000 2,181E-03 0,01966404 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 1,000 2,181E-03 0,01959175 GO:0060675|ureteric bud morphogenesis, ! T cell differentiation in the thymus GO:0033077 37 14 1,000 2,181E-03 0,01951998 ! response to gamma radiation GO:0010332 30 14 1,000 2,181E-03 0,01944874 ! regulation of RNA stability GO:0043487 33 14 1,000 2,181E-03 0,01937802 ! regulation of leukocyte proliferation GO:0070663 97 53 2,000 2,407E-03 0,0213043 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! cartilage development GO:0051216 99 53 2,000 2,407E-03 0,02122739 ! synapse organization GO:0050808 102 53 2,000 2,407E-03 0,02115103 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 2,509E-03 0,02196628 ! response to cAMP GO:0051591 25 15 1,000 2,509E-03 0,02188783 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 1,000 2,509E-03 0,02180994 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 2,509E-03 0,0217326 ! muscle maintenance GO:0046716 26 15 1,000 2,509E-03 0,0216558 ! dopamine metabolic process GO:0042417 35 15 1,000 2,509E-03 0,02157955 ! lymphocyte homeostasis GO:0002260 33 15 1,000 2,509E-03 0,02150383 ! actin filament polymerization GO:0030041 27 15 1,000 2,509E-03 0,02142864 ! neuromuscular process GO:0050905 107 54 2,000 2,539E-03 0,02161374 ! regulation of muscle contraction GO:0006937 94 54 2,000 2,539E-03 0,02153869 ! regulation of multicellular organism growth GO:0040014 90 55 2,000 2,676E-03 0,02261962 ! response to UV GO:0009411 120 55 2,000 2,676E-03 0,02254162 ! glucose catabolic process GO:0006007 88 56 2,000 2,817E-03 0,02364911 ! regulation of DNA replication GO:0006275 105 56 2,000 2,817E-03 0,02356812 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 2,858E-03 0,02382628 ! heterophilic cell adhesion GO:0007157 43 16 1,000 2,858E-03 0,02374524 ! fructose metabolic process GO:0006000 25 16 1,000 2,858E-03 0,02366475 ! biomineral formation GO:0031214 22 16 1,000 2,858E-03 0,0235848 ! aging GO:0007568 112 58 2,000 3,113E-03 0,02560495 ! metencephalon development GO:0022037 32 17 1,000 3,228E-03 0,02646289 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 3,228E-03 0,02637438 ! signal complex assembly GO:0007172 47 17 1,000 3,228E-03 0,02628647 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 1,000 3,228E-03 0,02619914 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 3,228E-03 0,02611238 ! regulation of survival gene product expression GO:0045884 38 17 1,000 3,228E-03 0,0260262 ! regulation of protein binding GO:0043393 33 17 1,000 3,228E-03 0,02594059 ! branched chain family amino acid metabolic process GO:0009081 37 17 1,000 3,228E-03 0,02585554 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 1,000 3,228E-03 0,02577105 ! DNA catabolic process GO:0006308 94 60 2,000 3,427E-03 0,02727157 ! positive regulation of secretion GO:0051047 110 61 2,000 3,591E-03 0,02848486 ! regulation of heart contraction GO:0008016 123 61 2,000 3,591E-03 0,02839267 ! negative regulation of response to stimulus GO:0048585 106 61 2,000 3,591E-03 0,02830108 ! regulation of viral genome replication GO:0045069 30 18 1,000 3,62E-03 0,0284327 ! cell-substrate junction assembly GO:0007044 56 18 1,000 3,62E-03 0,02834157 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 1,000 3,62E-03 0,02825102 ! negative regulation of protein catabolic process GO:0042177 42 18 1,000 3,62E-03 0,02816105 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 1,000 3,62E-03 0,02807165 ! defense response to virus GO:0051607 43 18 1,000 3,62E-03 0,02798281 ! regulation of neuronal synaptic plasticity GO:0048168 51 19 1,000 4,032E-03 0,03107398 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 1,000 4,032E-03 0,03097626 ! memory GO:0007613 34 19 1,000 4,032E-03 0,03087916 ! regulation of postsynaptic membrane potential GO:0060078 38 19 1,000 4,032E-03 0,03078266 ! pigmentation during development GO:0048066 42 19 1,000 4,032E-03 0,03068676 ! neuromuscular junction development GO:0007528 43 19 1,000 4,032E-03 0,03059146 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 4,032E-03 0,03049675 ! visual learning GO:0008542 38 19 1,000 4,032E-03 0,03040263 ! cellular pigmentation GO:0033059 37 19 1,000 4,032E-03 0,03030908 ! protein amino acid autophosphorylation GO:0046777 157 64 2,000 4,112E-03 0,03081569 ! skin development GO:0043588 42 20 1,000 4,465E-03 0,03336103 ! transcription from RNA polymerase III promoter GO:0006383 46 20 1,000 4,465E-03 0,03325932 ! regulation of carbohydrate metabolic process GO:0006109 37 20 1,000 4,465E-03 0,03315823 GO:0010675|regulation of cellular carbohydrate metabolic process, ! cellular response to unfolded protein GO:0034620 35 20 1,000 4,465E-03 0,03305775 GO:0030968|endoplasmic reticulum unfolded protein response, ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 4,465E-03 0,03295787 ! fatty acid beta-oxidation GO:0006635 36 20 1,000 4,465E-03 0,0328586 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 1,000 4,465E-03 0,03275993 ! negative regulation of translation GO:0017148 32 20 1,000 4,465E-03 0,03266185 ! ear development GO:0043583 114 66 2,000 4,484E-03 0,03269655 ! regulation of lipid metabolic process GO:0019216 132 66 2,000 4,484E-03 0,03259924 ! activation of MAPK activity GO:0000187 124 67 2,000 4,677E-03 0,03390224 ! hexose catabolic process GO:0019320 113 68 2,000 4,875E-03 0,03523338 ! extracellular matrix organization GO:0030198 146 68 2,000 4,875E-03 0,03512945 ! adaptive immune response GO:0002250 126 68 2,000 4,875E-03 0,03502612 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! ovarian follicle development GO:0001541 39 21 1,000 4,919E-03 0,03524298 ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 1,000 4,919E-03 0,03513993 ! plasma membrane fusion GO:0045026 33 21 1,000 4,919E-03 0,03503748 ! prostaglandin metabolic process GO:0006693 43 21 1,000 4,919E-03 0,03493563 GO:0006692|prostanoid metabolic process, ! collagen fibril organization GO:0030199 62 21 1,000 4,919E-03 0,03483437 ! negative regulation of angiogenesis GO:0016525 49 21 1,000 4,919E-03 0,03473369 ! actin filament-based movement GO:0030048 47 21 1,000 4,919E-03 0,03463359 ! homeostasis of number of cells GO:0048872 131 69 2,000 5,078E-03 0,0356463 ! actin polymerization or depolymerization GO:0008154 52 22 1,000 5,394E-03 0,03775453 ! ureteric bud development GO:0001657 50 22 1,000 5,394E-03 0,03764666 ! cell aging GO:0007569 48 22 1,000 5,394E-03 0,0375394 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 1,000 5,394E-03 0,03743275 ! renal system process GO:0003014 42 22 1,000 5,394E-03 0,03732671 ! G1 phase GO:0051318 44 22 1,000 5,394E-03 0,03722127 ! response to glucocorticoid stimulus GO:0051384 42 22 1,000 5,394E-03 0,03711642 ! peptidyl-serine modification GO:0018209 50 22 1,000 5,394E-03 0,03701216 ! response to cytokine stimulus GO:0034097 69 22 1,000 5,394E-03 0,03690849 ! gut development GO:0048565 44 22 1,000 5,394E-03 0,03680539 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 5,394E-03 0,03670287 ! cell cycle checkpoint GO:0000075 145 71 2,000 5,499E-03 0,03731642 ! actin filament organization GO:0007015 167 72 2,000 5,717E-03 0,03868988 ! positive regulation of DNA replication GO:0045740 44 23 1,000 5,888E-03 0,03973468 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 1,000 5,888E-03 0,03962522 ! glycerol metabolic process GO:0006071 40 23 1,000 5,888E-03 0,03951636 ! regeneration GO:0031099 42 23 1,000 5,888E-03 0,03940809 ! visual behavior GO:0007632 46 23 1,000 5,888E-03 0,03930042 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 1,000 6,402E-03 0,04261639 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 6,402E-03 0,04250058 ! regulation of cellular catabolic process GO:0031329 55 24 1,000 6,402E-03 0,04238541 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 1,000 6,402E-03 0,04227085 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 1,000 6,402E-03 0,04215691 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! sex determination GO:0007530 48 24 1,000 6,402E-03 0,04204359 ! regulation of viral reproduction GO:0050792 41 24 1,000 6,402E-03 0,04193087 ! membrane depolarization GO:0051899 45 24 1,000 6,402E-03 0,04181876 ! oogenesis GO:0048477 44 24 1,000 6,402E-03 0,04170724 ! regulation of oxidoreductase activity GO:0051341 48 24 1,000 6,402E-03 0,04159632 ! negative regulation of catabolic process GO:0009895 52 24 1,000 6,402E-03 0,04148598 ! cell-matrix adhesion GO:0007160 181 76 2,000 6,642E-03 0,04292486 ! monosaccharide catabolic process GO:0046365 125 77 2,000 6,886E-03 0,0443855 ! regulation of catabolic process GO:0009894 173 77 2,000 6,886E-03 0,04426869 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 6,936E-03 0,04447402 ! dicarboxylic acid metabolic process GO:0043648 48 25 1,000 6,936E-03 0,04435759 ! vasculogenesis GO:0001570 49 25 1,000 6,936E-03 0,04424178 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 6,936E-03 0,04412656 ! interaction with host GO:0051701 66 25 1,000 6,936E-03 0,04401195 ! lymphocyte proliferation GO:0046651 55 25 1,000 6,936E-03 0,04389793 ! leukocyte homeostasis GO:0001776 50 25 1,000 6,936E-03 0,0437845 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 7,39E-03 0,0465305 ! response to steroid hormone stimulus GO:0048545 147 79 2,000 7,39E-03 0,04641089 ! regulation of synaptic transmission GO:0050804 159 79 2,000 7,39E-03 0,04629189 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 1,000 7,489E-03 0,04679438 ! myelination GO:0042552 50 26 1,000 7,489E-03 0,04667501 ! molting cycle process GO:0022404 52 26 1,000 7,489E-03 0,04655624 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! multicellular organismal response to stress GO:0033555 61 26 1,000 7,489E-03 0,04643808 ! response to endoplasmic reticulum stress GO:0034976 46 26 1,000 7,489E-03 0,04632051 ! positive regulation of nuclear division GO:0051785 41 26 1,000 7,489E-03 0,04620354 GO:0045840|positive regulation of mitosis, ! regulation of osteoblast differentiation GO:0045667 68 26 1,000 7,489E-03 0,04608716 ! alditol metabolic process GO:0019400 44 26 1,000 7,489E-03 0,04597136 ! response to hypoxia GO:0001666 178 81 2,000 7,916E-03 0,04846522 ! mitochondrial membrane organization GO:0007006 60 27 1,000 8,062E-03 0,0492393 ! response to toxin GO:0009636 49 27 1,000 8,062E-03 0,0491165 ! leukocyte proliferation GO:0070661 59 27 1,000 8,062E-03 0,04899432 GO:0032943|mononuclear cell proliferation, ! cell-substrate adhesion GO:0031589 189 82 2,000 8,186E-03 0,04962578 ! response to oxygen levels GO:0070482 183 83 2,000 8,463E-03 0,05117314 ! spliceosomal snRNP biogenesis GO:0000387 40 28 1,000 8,654E-03 0,0522011 ! glutathione metabolic process GO:0006749 42 28 1,000 8,654E-03 0,05207253 ! lipid oxidation GO:0034440 48 28 1,000 8,654E-03 0,05194458 GO:0019395|fatty acid oxidation, ! response to metal ion GO:0010038 158 84 2,000 8,744E-03 0,05235773 ! T cell activation GO:0042110 189 84 2,000 8,744E-03 0,05222972 ! regulation of ligase activity GO:0051340 147 84 2,000 8,744E-03 0,05210233 ! negative regulation of transport GO:0051051 164 85 2,000 9,031E-03 0,05368191 ! regulation of transmission of nerve impulse GO:0051969 167 85 2,000 9,031E-03 0,05355161 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 9,265E-03 0,05480215 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 9,265E-03 0,05466978 ! catechol metabolic process GO:0009712 55 29 1,000 9,265E-03 0,05453805 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! ER-nuclear signaling pathway GO:0006984 52 29 1,000 9,265E-03 0,05440694 ! response to organic cyclic substance GO:0014070 58 29 1,000 9,265E-03 0,05427647 ! synaptogenesis GO:0007416 46 29 1,000 9,265E-03 0,05414662 ! negative regulation of neuron apoptosis GO:0043524 69 29 1,000 9,265E-03 0,0540174 ! alcohol catabolic process GO:0046164 142 87 2,000 9,622E-03 0,05596666 ! phenol metabolic process GO:0018958 56 30 1,000 9,894E-03 0,05741272 ! immune response-activating signal transduction GO:0002757 58 30 1,000 9,894E-03 0,05727667 GO:0002764|immune response-regulating signal transduction, ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 9,894E-03 0,05714127 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 1,000 9,894E-03 0,0570065 GO:0048871|multicellular organismal homeostasis, ! regulation of B cell activation GO:0050864 55 30 1,000 9,894E-03 0,05687237 ! cell junction assembly GO:0034329 85 31 1,000 0,01054169 0,06045389 ! ovulation cycle process GO:0022602 55 31 1,000 0,01054169 0,06031231 ! male gonad development GO:0008584 56 31 1,000 0,01054169 0,06017139 ! iron ion homeostasis GO:0055072 60 31 1,000 0,01054169 0,06003113 ! erythrocyte differentiation GO:0030218 62 31 1,000 0,01054169 0,05989152 ! ensheathment of neurons GO:0007272 64 31 1,000 0,01054169 0,05975257 GO:0008366|axon ensheathment, ! fatty acid catabolic process GO:0009062 54 31 1,000 0,01054169 0,05961425 ! response to heat GO:0009408 54 31 1,000 0,01054169 0,05947657 ! regulation of cell cycle process GO:0010564 161 90 2,000 0,01054896 0,05938043 ! ossification GO:0001503 205 91 2,000 0,01086912 0,06104198 ! bone development GO:0060348 206 92 2,000 0,01119486 0,06272717 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 1,000 0,01120778 0,06265585 ! collagen metabolic process GO:0032963 49 32 1,000 0,01120778 0,0625128 ! metanephros development GO:0001656 81 32 1,000 0,01120778 0,0623704 ! ovulation cycle GO:0042698 57 32 1,000 0,01120778 0,06222865 ! peripheral nervous system development GO:0007422 68 32 1,000 0,01120778 0,06208754 ! hindbrain development GO:0030902 65 32 1,000 0,01120778 0,06194707 ! positive regulation of catabolic process GO:0009896 72 32 1,000 0,01120778 0,06180723 ! response to ionizing radiation GO:0010212 74 33 1,000 0,01189194 0,06543248 ! regulation of defense response GO:0031347 171 95 2,000 0,01220571 0,06700799 ! negative regulation of multicellular organismal process GO:0051241 174 95 2,000 0,01220571 0,06685775 ! response to protein stimulus GO:0051789 158 96 2,000 0,01255392 0,06861126 ! regulation of T cell activation GO:0050863 175 96 2,000 0,01255392 0,06845811 ! glial cell differentiation GO:0010001 67 34 1,000 0,01259399 0,06852366 ! post-embryonic development GO:0009791 76 34 1,000 0,01259399 0,06837139 ! adult locomotory behavior GO:0008344 62 34 1,000 0,01259399 0,06821979 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,01259399 0,06806886 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 0,01331373 0,0718001 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 1,000 0,01331373 0,07164195 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 1,000 0,01405097 0,07544287 ! negative regulation of DNA binding GO:0043392 67 36 1,000 0,01405097 0,07527743 ! positive regulation of cell development GO:0010720 85 36 1,000 0,01405097 0,07511271 ! regulation of muscle development GO:0048634 82 36 1,000 0,01405097 0,07494871 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,01405097 0,07478542 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 0,01405097 0,07462284 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,0148055 0,07845954 ! sister chromatid segregation GO:0000819 65 37 1,000 0,0148055 0,07828971 ! odontogenesis GO:0042476 74 37 1,000 0,0148055 0,07812062 ! cell junction organization GO:0034330 96 37 1,000 0,0148055 0,07795226 ! tissue remodeling GO:0048771 78 37 1,000 0,0148055 0,07778462 ! female gonad development GO:0008585 71 37 1,000 0,0148055 0,0776177 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 0,01557716 0,08148822 ! meiosis I GO:0007127 74 38 1,000 0,01557716 0,0813141 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 1,000 0,01557716 0,08114073 ! glycogen metabolic process GO:0005977 63 38 1,000 0,01557716 0,08096809 ! pigment metabolic process GO:0042440 87 38 1,000 0,01557716 0,08079618 ! negative regulation of binding GO:0051100 71 39 1,000 0,01636574 0,08470658 ! erythrocyte homeostasis GO:0034101 75 39 1,000 0,01636574 0,0845275 ! glucan metabolic process GO:0044042 64 39 1,000 0,01636574 0,08434917 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 1,000 0,01717106 0,08831349 ! development of primary female sexual characteristics GO:0046545 80 40 1,000 0,01717106 0,08812796 GO:0046660|female sex differentiation, ! mismatch repair GO:0006298 58 40 1,000 0,01717106 0,08794321 ! regulation of action potential in neuron GO:0019228 80 40 1,000 0,01717106 0,08775923 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 1,000 0,01799294 0,09176776 ! cellular amide metabolic process GO:0043603 73 41 1,000 0,01799294 0,09157657 ! gliogenesis GO:0042063 91 41 1,000 0,01799294 0,09138619 ! feeding behavior GO:0007631 69 41 1,000 0,01799294 0,09119659 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 1,000 0,01883119 0,09524761 ! ear morphogenesis GO:0042471 64 42 1,000 0,01883119 0,09505082 ! T cell differentiation GO:0030217 93 42 1,000 0,01883119 0,09485484 ! cytokinesis GO:0000910 84 42 1,000 0,01883119 0,09465966 ! calcium-dependent cell-cell adhesion GO:0016339 56 43 1,000 0,01968563 0,0987515 ! striated muscle cell differentiation GO:0051146 91 43 1,000 0,01968563 0,09854914 ! development of primary male sexual characteristics GO:0046546 80 43 1,000 0,01968563 0,09834761 ! neuron migration GO:0001764 85 43 1,000 0,01968563 0,0981469 ! regulation of myeloid cell differentiation GO:0045637 105 43 1,000 0,01968563 0,09794701 ! energy reserve metabolic process GO:0006112 76 44 1,000 0,02055607 0,10207007 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 0,02144234 0,10625483 ! regulation of epithelial cell proliferation GO:0050678 122 45 1,000 0,02144234 0,10603974 ! B cell differentiation GO:0030183 124 45 1,000 0,02144234 0,10582552 ! female gamete generation GO:0007292 71 45 1,000 0,02144234 0,10561216 ! polyol metabolic process GO:0019751 77 45 1,000 0,02144234 0,10539966 ! developmental growth GO:0048589 88 45 1,000 0,02144234 0,10518802 ! regulation of gene-specific transcription GO:0032583 102 46 1,000 0,02234426 0,10939282 ! mitochondrial transport GO:0006839 94 48 1,000 0,02419433 0,11821351 ! regulation of JAK-STAT cascade GO:0046425 76 48 1,000 0,02419433 0,11797756 ! endosome transport GO:0016197 127 48 1,000 0,02419433 0,11774254 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,02419433 0,11750846 ! male sex differentiation GO:0046661 93 48 1,000 0,02419433 0,11727531 ! icosanoid metabolic process GO:0006690 92 48 1,000 0,02419433 0,11704308 ! JAK-STAT cascade GO:0007259 82 48 1,000 0,02419433 0,11681177 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02479123 0,11945756 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02479123 0,11922241 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02479123 0,11898818 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02479123 0,11875487 ! neuron fate determination GO:0048664 7 5 0,000 0,02479123 0,11852247 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02479123 0,11829098 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02479123 0,1180604 ! hemoglobin biosynthetic process GO:0042541 8 5 0,000 0,02479123 0,11783071 ! polyol transport GO:0015791 12 5 0,000 0,02479123 0,11760191 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02479123 0,117374 ! response to superoxide GO:0000303 10 5 0,000 0,02479123 0,11714697 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02479123 0,11692082 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02479123 0,11669554 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02479123 0,11647112 ! female meiosis GO:0007143 10 5 0,000 0,02479123 0,11624757 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02479123 0,11602487 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02479123 0,11580303 ! hypothalamus development GO:0021854 9 5 0,000 0,02479123 0,11558203 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02479123 0,11536187 ! cobalt ion transport GO:0006824 11 5 0,000 0,02479123 0,11514255 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02479123 0,11492407 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02479123 0,11470641 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02479123 0,11448957 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02479123 0,11427355 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02479123 0,11405835 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02479123 0,11384395 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,02479123 0,11363036 GO:0006451|translational readthrough, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02479123 0,11341757 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02479123 0,11320558 ! transposition GO:0032196 9 5 0,000 0,02479123 0,11299437 ! negative chemotaxis GO:0050919 16 5 0,000 0,02479123 0,11278395 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02479123 0,11257432 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02479123 0,11236546 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02479123 0,11215738 ! behavioral response to pain GO:0048266 10 5 0,000 0,02479123 0,11195006 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02479123 0,11174351 ! Notch receptor processing GO:0007220 11 5 0,000 0,02479123 0,11153772 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02479123 0,11133269 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! micturition GO:0060073 9 5 0,000 0,02479123 0,11112841 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02479123 0,11092488 ! copulation GO:0007620 9 5 0,000 0,02479123 0,11072209 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02479123 0,11052004 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02479123 0,11031873 ! bioluminescence GO:0008218 9 5 0,000 0,02479123 0,11011815 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02479123 0,1099183 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02479123 0,10971917 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02479123 0,10952076 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02479123 0,10932307 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02479123 0,1091261 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02479123 0,10892983 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02479123 0,10873426 ! grooming behavior GO:0007625 6 5 0,000 0,02479123 0,1085394 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02479123 0,10834523 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02479123 0,10815175 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02479123 0,10795897 ! response to protozoan GO:0001562 13 5 0,000 0,02479123 0,10776687 ! lymph vessel development GO:0001945 10 5 0,000 0,02479123 0,10757546 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02479123 0,10738472 ! endochondral ossification GO:0001958 17 5 0,000 0,02479123 0,10719466 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02479123 0,10700527 ! single strand break repair GO:0000012 8 5 0,000 0,02479123 0,10681655 ! anagen GO:0042640 7 5 0,000 0,02479123 0,10662849 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02479123 0,10644109 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02479123 0,10625436 ! cytokine secretion GO:0050663 15 5 0,000 0,02479123 0,10606827 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02479123 0,10588284 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02479123 0,10569805 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02479123 0,10551391 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02479123 0,1053304 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02479123 0,10514754 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02479123 0,10496531 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02479123 0,10478371 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02479123 0,10460273 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02479123 0,10442238 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02479123 0,10424266 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02479123 0,10406354 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02479123 0,10388505 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02479123 0,10370716 ! microvillus organization GO:0032528 8 5 0,000 0,02479123 0,10352989 GO:0030033|microvillus assembly, ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02479123 0,10335321 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02479123 0,10317714 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02479123 0,10300167 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02479123 0,1028268 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02479123 0,10265251 ! polyol catabolic process GO:0046174 9 5 0,000 0,02479123 0,10247882 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02479123 0,10230571 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02479123 0,10213319 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02479123 0,10196125 ! muscle cell migration GO:0014812 8 5 0,000 0,02479123 0,10178989 ! mitochondrial fission GO:0000266 8 5 0,000 0,02479123 0,1016191 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02479123 0,10144888 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02479123 0,10127924 ! mRNA transcription GO:0009299 10 5 0,000 0,02479123 0,10111015 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02479123 0,10094164 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02479123 0,10077368 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02479123 0,10060628 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02479123 0,10043944 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02479123 0,10027315 ! monocyte activation GO:0042117 10 5 0,000 0,02479123 0,10010741 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02479123 0,09994222 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02479123 0,09977757 ! response to food GO:0032094 6 5 0,000 0,02479123 0,09961346 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02479123 0,09944989 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02479123 0,09928686 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02479123 0,09912436 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02479123 0,09896239 ! regulation of phospholipase A2 activity GO:0032429 15 5 0,000 0,02479123 0,09880095 ! forebrain neuron development GO:0021884 13 5 0,000 0,02479123 0,09864004 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02479123 0,09847965 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02479123 0,09831978 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02479123 0,09816043 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02479123 0,09800159 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02479123 0,09784327 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02479123 0,09768546 ! lipid glycosylation GO:0030259 7 5 0,000 0,02479123 0,09752815 ! nucleobase transport GO:0015851 6 5 0,000 0,02479123 0,09737135 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02479123 0,09721506 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02479123 0,09705927 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02479123 0,09690397 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02479123 0,09674917 ! basic amino acid transport GO:0015802 12 5 0,000 0,02479123 0,09659487 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02479123 0,09644106 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02479123 0,09628773 ! actin nucleation GO:0045010 11 5 0,000 0,02479123 0,09613489 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02479123 0,09598254 ! depurination GO:0045007 5 5 0,000 0,02479123 0,09583067 ! depyrimidination GO:0045008 10 5 0,000 0,02479123 0,09567928 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02479123 0,09552836 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02479123 0,09537793 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02479123 0,09522796 GO:0031572|G2/M transition DNA damage checkpoint, ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02479123 0,09507847 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02479123 0,09492944 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02479123 0,09478088 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02479123 0,09463279 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02479123 0,09448515 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02479123 0,09433798 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02479123 0,09419126 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02479123 0,094045 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02479123 0,0938992 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02479123 0,09375384 ! response to arsenic GO:0046685 11 5 0,000 0,02479123 0,09360894 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02479123 0,09346448 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02479123 0,09332047 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02479123 0,0931769 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02479123 0,09303377 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02479123 0,09289108 ! response to mercury ion GO:0046689 8 5 0,000 0,02479123 0,09274883 ! response to cadmium ion GO:0046686 7 5 0,000 0,02479123 0,09260701 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02479123 0,09246562 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02479123 0,09232467 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02479123 0,09218414 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02479123 0,09204405 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02479123 0,09190437 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02479123 0,09176513 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02479123 0,0916263 ! decidualization GO:0046697 11 5 0,000 0,02479123 0,09148789 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02479123 0,0913499 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02479123 0,09121232 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02479123 0,09107516 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02479123 0,09093841 ! embryonic cleavage GO:0040016 6 5 0,000 0,02479123 0,09080207 ! peroxisome fission GO:0016559 5 5 0,000 0,02479123 0,09066614 ! histone demethylation GO:0016577 13 5 0,000 0,02479123 0,09053062 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02479123 0,0903955 ! mitotic recombination GO:0006312 9 5 0,000 0,02479123 0,09026078 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02479123 0,09012646 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02479123 0,08999254 ! metaphase plate congression GO:0051310 7 5 0,000 0,02479123 0,08985902 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02479123 0,0897259 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,02479123 0,08959317 ! enteric nervous system development GO:0048484 8 5 0,000 0,02479123 0,08946083 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02479123 0,08932888 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02479123 0,08919732 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02479123 0,08906615 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02479123 0,08893536 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02479123 0,08880496 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02479123 0,08867494 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02479123 0,0885453 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02479123 0,08841603 ! metaphase GO:0051323 11 5 0,000 0,02479123 0,08828715 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02479123 0,08815864 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02479123 0,0880305 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02479123 0,08790273 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02479123 0,08777534 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02479123 0,08764831 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02479123 0,08752165 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02479123 0,08739536 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02479123 0,08726943 ! response to redox state GO:0051775 6 5 0,000 0,02479123 0,08714386 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02479123 0,08701865 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02479123 0,08689381 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02479123 0,08676932 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02479123 0,08664518 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02479123 0,0865214 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02479123 0,08639798 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02479123 0,0862749 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02479123 0,08615218 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02479123 0,08602981 ! striatum development GO:0021756 14 5 0,000 0,02479123 0,08590778 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02479123 0,08578609 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02479123 0,08566476 ! glial cell migration GO:0008347 10 5 0,000 0,02479123 0,08554376 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02479123 0,08542311 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02479123 0,08530279 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02479123 0,08518282 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02479123 0,08506318 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02479123 0,08494387 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02479123 0,08482491 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02479123 0,08470627 ! neuroprotection GO:0043526 8 5 0,000 0,02479123 0,08458796 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02479123 0,08446999 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02479123 0,08435234 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02479123 0,08423502 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02479123 0,08411803 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02479123 0,08400136 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02479123 0,08388502 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02479123 0,08376899 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! protein insertion into membrane GO:0051205 17 5 0,000 0,02479123 0,08365329 ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02479123 0,08353791 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02479123 0,08342284 ! spindle assembly GO:0051225 6 5 0,000 0,02479123 0,08330809 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02479123 0,08319366 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02479123 0,08307954 ! protein palmitoylation GO:0018345 12 5 0,000 0,02479123 0,08296573 ! drug metabolic process GO:0017144 7 5 0,000 0,02479123 0,08285223 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02479123 0,08273905 ! organ regeneration GO:0031100 7 5 0,000 0,02479123 0,08262617 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02479123 0,0825136 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02479123 0,08240134 ! response to calcium ion GO:0051592 94 49 1,000 0,02514214 0,08345414 ! detection of stimulus involved in sensory perception GO:0050906 75 49 1,000 0,02514214 0,08334091 ! JNK cascade GO:0007254 106 49 1,000 0,02514214 0,08322798 ! protein homooligomerization GO:0051260 84 49 1,000 0,02514214 0,08311536 ! regulation of action potential GO:0001508 102 50 1,000 0,0261049 0,08618143 ! endocrine system development GO:0035270 109 50 1,000 0,0261049 0,08606513 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 1,000 0,02708243 0,08916762 ! peptide metabolic process GO:0006518 80 51 1,000 0,02708243 0,08904761 ! response to temperature stimulus GO:0009266 84 51 1,000 0,02708243 0,08892792 ! detection of abiotic stimulus GO:0009582 80 51 1,000 0,02708243 0,08880855 ! response to estrogen stimulus GO:0043627 98 52 1,000 0,02807457 0,09193856 ! unsaturated fatty acid metabolic process GO:0033559 98 52 1,000 0,02807457 0,09181549 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 0,02807457 0,09169274 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 1,000 0,02908114 0,09485345 ! vesicle organization GO:0016050 127 53 1,000 0,02908114 0,09472698 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,02908114 0,09460085 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02967565 0,09640639 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02967565 0,09627836 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02967565 0,09615067 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02967565 0,09602332 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02967565 0,0958963 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02967565 0,09576962 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02967565 0,09564328 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02967565 0,09551727 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02967565 0,09539158 ! response to oxygen radical GO:0000305 11 6 0,000 0,02967565 0,09526623 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02967565 0,09514121 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02967565 0,09501652 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02967565 0,09489215 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02967565 0,09476811 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,02967565 0,09464439 ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02967565 0,094521 ! forebrain regionalization GO:0021871 9 6 0,000 0,02967565 0,09439792 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02967565 0,09427517 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02967565 0,09415273 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02967565 0,09403062 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02967565 0,09390881 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02967565 0,09378733 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02967565 0,09366616 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02967565 0,0935453 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02967565 0,09342475 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02967565 0,09330451 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02967565 0,09318458 ! malate metabolic process GO:0006108 13 6 0,000 0,02967565 0,09306496 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02967565 0,09294565 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02967565 0,09282664 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02967565 0,09270793 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02967565 0,09258953 ! protein refolding GO:0042026 15 6 0,000 0,02967565 0,09247143 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02967565 0,09235364 ! opsonization GO:0008228 8 6 0,000 0,02967565 0,09223614 ! mating behavior GO:0007617 7 6 0,000 0,02967565 0,09211894 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02967565 0,09200204 ! embryonic hemopoiesis GO:0035162 16 6 0,000 0,02967565 0,09188543 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02967565 0,09176912 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02967565 0,0916531 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02967565 0,09153738 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02967565 0,09142195 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02967565 0,09130681 ! toxin metabolic process GO:0009404 11 6 0,000 0,02967565 0,09119195 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02967565 0,09107739 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,02967565 0,09096312 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02967565 0,09084913 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02967565 0,09073542 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,02967565 0,09062201 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02967565 0,09050887 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02967565 0,09039602 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02967565 0,09028344 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02967565 0,09017115 ! thymic T cell selection GO:0045061 16 6 0,000 0,02967565 0,09005914 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02967565 0,0899474 ! protein lipoylation GO:0009249 10 6 0,000 0,02967565 0,08983594 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02967565 0,08972476 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02967565 0,08961385 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02967565 0,08950322 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02967565 0,08939285 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02967565 0,08928276 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02967565 0,08917294 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02967565 0,0890634 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02967565 0,08895412 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02967565 0,0888451 ! hyperosmotic response GO:0006972 10 6 0,000 0,02967565 0,08873636 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02967565 0,08862788 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02967565 0,08851966 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02967565 0,08841171 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02967565 0,08830402 ! urea metabolic process GO:0019627 7 6 0,000 0,02967565 0,0881966 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02967565 0,08808943 ! neutrophil activation GO:0042119 7 6 0,000 0,02967565 0,08798253 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02967565 0,08787588 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02967565 0,0877695 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02967565 0,08766337 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02967565 0,08755749 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02967565 0,08745187 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02967565 0,08734651 ! neuron apoptosis GO:0051402 15 6 0,000 0,02967565 0,0872414 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,02967565 0,08713654 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02967565 0,08703194 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02967565 0,08692758 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02967565 0,08682348 ! carnitine transport GO:0015879 10 6 0,000 0,02967565 0,08671962 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02967565 0,08661601 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02967565 0,08651265 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02967565 0,08640954 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,02967565 0,08630667 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02967565 0,08620405 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02967565 0,08610167 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02967565 0,08599953 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02967565 0,08589764 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02967565 0,08579598 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02967565 0,08569457 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02967565 0,08559339 GO:0045686|negative regulation of glial cell differentiation, ! response to UV-C GO:0010225 14 6 0,000 0,02967565 0,08549246 ! astrocyte development GO:0014002 16 6 0,000 0,02967565 0,08539176 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02967565 0,0852913 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02967565 0,08519107 ! interaction with symbiont GO:0051702 14 6 0,000 0,02967565 0,08509108 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02967565 0,08499133 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02967565 0,08489181 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02967565 0,08479252 ! response to copper ion GO:0046688 10 6 0,000 0,02967565 0,08469346 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02967565 0,08459464 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02967565 0,08449604 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02967565 0,08439768 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02967565 0,08429954 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02967565 0,08420163 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02967565 0,08410395 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02967565 0,08400649 ! hair follicle maturation GO:0048820 8 6 0,000 0,02967565 0,08390926 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02967565 0,08381226 ! Schwann cell development GO:0014044 15 6 0,000 0,02967565 0,08371548 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02967565 0,08361892 ! response to pheromone GO:0019236 6 6 0,000 0,02967565 0,08352259 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02967565 0,08342647 ! regulation of interleukin-13 production GO:0032656 12 6 0,000 0,02967565 0,08333058 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02967565 0,08323491 ! subpallium development GO:0021544 15 6 0,000 0,02967565 0,08313945 ! neural tube patterning GO:0021532 8 6 0,000 0,02967565 0,08304422 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02967565 0,0829492 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02967565 0,0828544 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02967565 0,08275982 ! G2 phase GO:0051319 16 6 0,000 0,02967565 0,08266546 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02967565 0,0825713 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02967565 0,08247737 ! oxygen homeostasis GO:0032364 10 6 0,000 0,02967565 0,08238364 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02967565 0,08229013 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02967565 0,08219683 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02967565 0,08210374 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02967565 0,08201086 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02967565 0,0819182 ! receptor internalization GO:0031623 11 6 0,000 0,02967565 0,08182574 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,02967565 0,08173349 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,02967565 0,08164145 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02967565 0,08154961 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02967565 0,08145798 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02967565 0,08136656 ! protein deubiquitination GO:0016579 16 6 0,000 0,02967565 0,08127534 ! negative regulation of neuroblast proliferation GO:0007406 25 6 0,000 0,02967565 0,08118433 ! protein destabilization GO:0031648 9 6 0,000 0,02967565 0,08109352 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02967565 0,08100291 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02967565 0,0809125 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02967565 0,0808223 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02967565 0,0807323 ! negative regulation of axon extension GO:0030517 24 6 0,000 0,02967565 0,0806425 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02967565 0,08055289 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02967565 0,08046349 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02967565 0,08037428 ! determination of adult lifespan GO:0008340 17 6 0,000 0,02967565 0,08028528 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02967565 0,08019646 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02967565 0,08010785 ! neural plate development GO:0001840 9 6 0,000 0,02967565 0,08001943 ! catecholamine transport GO:0051937 9 6 0,000 0,02967565 0,07993121 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02967565 0,07984318 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02967565 0,07975534 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02967565 0,0796677 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02967565 0,07958025 ! maternal placenta development GO:0001893 12 6 0,000 0,02967565 0,07949299 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02967565 0,07940592 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02967565 0,07931904 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02967565 0,07923235 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02967565 0,07914586 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02967565 0,07905955 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02967565 0,07897343 GO:0055081|anion homeostasis, ! activation of phospholipase C activity GO:0007202 110 54 1,000 0,03010199 0,08002085 GO:0010863|positive regulation of phospholipase C activity, ! embryonic skeletal system development GO:0048706 101 54 1,000 0,03010199 0,07993387 ! membrane fusion GO:0006944 122 54 1,000 0,03010199 0,07984708 ! regulation of cell shape GO:0008360 142 54 1,000 0,03010199 0,07976048 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 0,03010199 0,07967406 ! positive regulation of phospholipase activity GO:0010518 111 55 1,000 0,03113694 0,08232418 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,03218583 0,08500538 ! regulation of phospholipase activity GO:0010517 113 57 1,000 0,03324849 0,08771712 ! heart morphogenesis GO:0003007 105 57 1,000 0,03324849 0,0876225 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,03432476 0,09036141 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,03432476 0,09026414 ! positive regulation of lipase activity GO:0060193 115 58 1,000 0,03432476 0,09016709 ! tRNA transcription GO:0009304 17 7 0,000 0,03453573 0,09062384 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03453573 0,0905266 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 14 7 0,000 0,03453573 0,09042958 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03453573 0,09033276 ! regulation of helicase activity GO:0051095 16 7 0,000 0,03453573 0,09023614 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03453573 0,09013974 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03453573 0,09004354 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03453573 0,08994754 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03453573 0,08985175 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03453573 0,08975616 ! prostate gland development GO:0030850 14 7 0,000 0,03453573 0,08966078 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03453573 0,0895656 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03453573 0,08947062 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03453573 0,08937584 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03453573 0,08928126 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03453573 0,08918689 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03453573 0,08909271 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03453573 0,08899873 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03453573 0,08890495 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03453573 0,08881136 ! glycolipid transport GO:0046836 11 7 0,000 0,03453573 0,08871797 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03453573 0,08862478 GO:0051923|sulfation, ! regulation of protein export from nucleus GO:0046825 10 7 0,000 0,03453573 0,08853179 ! neuron adhesion GO:0007158 14 7 0,000 0,03453573 0,08843899 ! N-terminal protein amino acid acetylation GO:0006474 14 7 0,000 0,03453573 0,08834638 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03453573 0,08825397 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03453573 0,08816175 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03453573 0,08806972 ! pericardium development GO:0060039 16 7 0,000 0,03453573 0,08797789 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03453573 0,08788624 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03453573 0,08779479 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03453573 0,08770353 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03453573 0,08761246 ! lipoprotein transport GO:0042953 14 7 0,000 0,03453573 0,08752157 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03453573 0,08743087 ! rhythmic behavior GO:0007622 17 7 0,000 0,03453573 0,08734037 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03453573 0,08725005 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03453573 0,08715991 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03453573 0,08706996 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03453573 0,0869802 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03453573 0,08689062 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03453573 0,08680123 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03453573 0,08671202 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03453573 0,08662299 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03453573 0,08653415 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03453573 0,08644549 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03453573 0,08635701 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03453573 0,08626871 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03453573 0,08618059 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03453573 0,08609265 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03453573 0,08600489 ! spinal cord patterning GO:0021511 14 7 0,000 0,03453573 0,08591731 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 0,000 0,03453573 0,0858299 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03453573 0,08574268 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,03453573 0,08565563 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03453573 0,08556876 ! adrenal gland development GO:0030325 17 7 0,000 0,03453573 0,08548206 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03453573 0,08539554 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03453573 0,0853092 ! ovulation GO:0030728 10 7 0,000 0,03453573 0,08522302 ! adenohypophysis development GO:0021984 11 7 0,000 0,03453573 0,08513703 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03453573 0,0850512 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03453573 0,08496555 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03453573 0,08488007 ! microtubule nucleation GO:0007020 21 7 0,000 0,03453573 0,08479477 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03453573 0,08470963 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03453573 0,08462467 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03453573 0,08453987 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03453573 0,08445525 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03453573 0,08437079 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03453573 0,08428651 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03453573 0,08420239 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03453573 0,08411844 ! galactose metabolic process GO:0006012 13 7 0,000 0,03453573 0,08403466 ! vesicle fusion GO:0006906 20 7 0,000 0,03453573 0,08395104 ! response to dietary excess GO:0002021 8 7 0,000 0,03453573 0,08386759 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03453573 0,0837843 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03453573 0,08370118 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03453573 0,08361823 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03453573 0,08353544 ! nucleoside transport GO:0015858 11 7 0,000 0,03453573 0,08345281 ! nucleoside salvage GO:0043174 11 7 0,000 0,03453573 0,08337035 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03453573 0,08328805 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03453573 0,08320591 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03453573 0,08312394 ! parturition GO:0007567 16 7 0,000 0,03453573 0,08304212 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03453573 0,08296047 ! rRNA modification GO:0000154 14 7 0,000 0,03453573 0,08287897 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03453573 0,08279764 ! spindle checkpoint GO:0031577 16 7 0,000 0,03453573 0,08271646 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,03453573 0,08263545 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03453573 0,08255459 ! monocyte differentiation GO:0030224 16 7 0,000 0,03453573 0,08247389 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03453573 0,08239335 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03453573 0,08231297 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03453573 0,08223274 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03453573 0,08215267 ! G1 DNA damage checkpoint GO:0031571 20 7 0,000 0,03453573 0,08207276 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03453573 0,081993 ! fibrinolysis GO:0042730 11 7 0,000 0,03453573 0,08191339 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03453573 0,08183394 ! eating behavior GO:0042755 8 7 0,000 0,03453573 0,08175465 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03453573 0,0816755 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03453573 0,08159651 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03453573 0,08151768 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03453573 0,08143899 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03453573 0,08136046 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03453573 0,08128208 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03453573 0,08120384 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03453573 0,08112576 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03453573 0,08104783 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03453573 0,08097005 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,03453573 0,08089242 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03453573 0,08081494 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,03453573 0,0807376 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03453573 0,08066042 ! histone ubiquitination GO:0016574 9 7 0,000 0,03453573 0,08058338 ! regulation of meiosis GO:0040020 12 7 0,000 0,03453573 0,08050648 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03453573 0,08042974 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03453573 0,08035314 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03453573 0,08027668 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03453573 0,08020037 ! transcription termination GO:0006353 14 7 0,000 0,03453573 0,08012421 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03453573 0,08004819 ! anaphase GO:0051322 18 7 0,000 0,03453573 0,07997232 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03453573 0,07989659 ! axonal fasciculation GO:0007413 19 7 0,000 0,03453573 0,079821 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03453573 0,07974555 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03453573 0,07967025 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03453573 0,07959509 GO:0015991|ATP hydrolysis coupled proton transport, ! diuresis GO:0030146 12 7 0,000 0,03453573 0,07952007 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03453573 0,07944519 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03453573 0,07937046 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03453573 0,07929586 ! antibiotic transport GO:0042891 9 7 0,000 0,03453573 0,0792214 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03453573 0,07914709 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03453573 0,07907291 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03453573 0,07899887 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03453573 0,07892497 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03453573 0,07885121 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03453573 0,07877759 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03453573 0,0787041 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03453573 0,07863075 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03453573 0,07855754 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03453573 0,07848446 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03453573 0,07841152 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03453573 0,07833871 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03453573 0,07826604 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03453573 0,07819351 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03453573 0,07812111 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03453573 0,07804884 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03453573 0,0779767 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03453573 0,0779047 ! muscle adaptation GO:0043500 13 7 0,000 0,03453573 0,07783284 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03453573 0,0777611 ! retina homeostasis GO:0001895 12 7 0,000 0,03453573 0,0776895 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03453573 0,07761803 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03453573 0,07754669 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03453573 0,07747548 ! establishment of organelle localization GO:0051656 122 59 1,000 0,03541448 0,07937393 ! lipid modification GO:0030258 112 60 1,000 0,0365175 0,08177108 ! adult behavior GO:0030534 104 60 1,000 0,0365175 0,0816962 ! kidney development GO:0001822 133 60 1,000 0,0365175 0,08162145 ! cytokine-mediated signaling pathway GO:0019221 112 61 1,000 0,03763364 0,0840393 ! viral reproductive process GO:0022415 132 62 1,000 0,03876276 0,08648167 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 0,03876276 0,08640276 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,03937161 0,0876799 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,03937161 0,08760004 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,03937161 0,08752033 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,03937161 0,08744077 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03937161 0,08736135 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03937161 0,08728208 ! male meiosis GO:0007140 9 8 0,000 0,03937161 0,08720294 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,03937161 0,08712396 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,03937161 0,08704511 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,03937161 0,08696641 ! meiotic prophase I GO:0007128 14 8 0,000 0,03937161 0,08688785 ! response to zinc ion GO:0010043 12 8 0,000 0,03937161 0,08680943 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03937161 0,08673115 ! oligopeptide transport GO:0006857 16 8 0,000 0,03937161 0,08665302 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,03937161 0,08657502 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,03937161 0,08649716 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,03937161 0,08641945 ! signal peptide processing GO:0006465 12 8 0,000 0,03937161 0,08634187 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,03937161 0,08626444 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,03937161 0,08618714 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03937161 0,08610998 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,03937161 0,08603296 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,03937161 0,08595607 ! estrogen metabolic process GO:0008210 17 8 0,000 0,03937161 0,08587933 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,03937161 0,08580272 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,03937161 0,08572625 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03937161 0,08564991 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03937161 0,08557371 ! reflex GO:0060004 17 8 0,000 0,03937161 0,08549764 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03937161 0,08542171 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,03937161 0,08534592 ! hemoglobin metabolic process GO:0020027 14 8 0,000 0,03937161 0,08527025 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03937161 0,08519473 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,03937161 0,08511933 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,03937161 0,08504407 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,03937161 0,08496895 ! astrocyte differentiation GO:0048708 19 8 0,000 0,03937161 0,08489395 ! histidine catabolic process GO:0006548 10 8 0,000 0,03937161 0,08481909 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03937161 0,08474436 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,03937161 0,08466976 ! L-phenylalanine metabolic process GO:0006558 12 8 0,000 0,03937161 0,08459529 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 13 8 0,000 0,03937161 0,08452096 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,03937161 0,08444675 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,03937161 0,08437267 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,03937161 0,08429873 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,03937161 0,08422491 ! macrophage activation GO:0042116 13 8 0,000 0,03937161 0,08415122 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03937161 0,08407766 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03937161 0,08400423 ! purine salvage GO:0043101 12 8 0,000 0,03937161 0,08393093 ! synaptic transmission, glutamatergic GO:0035249 24 8 0,000 0,03937161 0,08385776 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,03937161 0,08378471 ! osteoblast development GO:0002076 17 8 0,000 0,03937161 0,08371179 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,03937161 0,083639 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,03937161 0,08356633 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,03937161 0,08349379 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,03937161 0,08342138 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03937161 0,08334909 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,03937161 0,08327692 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03937161 0,08320489 ! intermediate filament organization GO:0045109 12 8 0,000 0,03937161 0,08313297 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,03937161 0,08306118 ! cellular extravasation GO:0045123 13 8 0,000 0,03937161 0,08298951 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,03937161 0,08291797 ! response to antibiotic GO:0046677 11 8 0,000 0,03937161 0,08284655 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,03937161 0,08277526 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,03937161 0,08270408 ! DNA topological change GO:0006265 12 8 0,000 0,03937161 0,08263303 ! response to tropane GO:0014073 15 8 0,000 0,03937161 0,0825621 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,03937161 0,08249129 ! regulation of interleukin-4 production GO:0032673 18 8 0,000 0,03937161 0,08242061 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03937161 0,08235004 ! mast cell activation GO:0045576 14 8 0,000 0,03937161 0,0822796 ! multicellular organismal aging GO:0010259 20 8 0,000 0,03937161 0,08220927 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,03937161 0,08213907 ! gas homeostasis GO:0033483 14 8 0,000 0,03937161 0,08206898 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,03937161 0,08199902 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,03937161 0,08192917 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,03937161 0,08185944 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03937161 0,08178984 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03937161 0,08172035 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,03937161 0,08165097 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03937161 0,08158172 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,03937161 0,08151258 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,03937161 0,08144356 ! intracellular lipid transport GO:0032365 16 8 0,000 0,03937161 0,08137466 ! response to tumor cell GO:0002347 16 8 0,000 0,03937161 0,08130587 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03937161 0,0812372 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,03937161 0,08116865 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 0,000 0,03937161 0,08110021 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03937161 0,08103188 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,03937161 0,08096368 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,03937161 0,08089558 ! hormone catabolic process GO:0042447 17 8 0,000 0,03937161 0,0808276 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,03937161 0,08075974 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,03937161 0,08069199 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,03937161 0,08062435 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,03937161 0,08055682 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03937161 0,08048941 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,03937161 0,08042211 ! adult feeding behavior GO:0008343 10 8 0,000 0,03937161 0,08035493 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,03937161 0,08028785 ! ATP catabolic process GO:0006200 11 8 0,000 0,03937161 0,08022089 ! blastocyst growth GO:0001832 19 8 0,000 0,03937161 0,08015404 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03937161 0,0800873 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03937161 0,08002067 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,03937161 0,07995415 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03937161 0,07988775 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,03937161 0,07982145 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,03937161 0,07975526 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,03937161 0,07968919 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,03937161 0,07962322 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,03937161 0,07955736 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,03937161 0,07949161 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03937161 0,07942597 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,03937161 0,07936043 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,03937161 0,07929501 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03937161 0,07922969 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,03937161 0,07916448 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,03937161 0,07909938 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,03937161 0,07903439 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,03937161 0,0789695 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,03937161 0,07890471 ! regulation of mitosis GO:0007088 112 63 1,000 0,0399047 0,07990752 GO:0051783|regulation of nuclear division, ! mesoderm development GO:0007498 128 63 1,000 0,0399047 0,07984208 ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,0399047 0,07977674 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 1,000 0,04222641 0,08434923 ! multicellular organism reproduction GO:0032504 123 65 1,000 0,04222641 0,08428032 GO:0048609|reproductive process in a multicellular organism, ! gonad development GO:0008406 115 66 1,000 0,04340587 0,08656371 ! axon extension GO:0048675 16 9 0,000 0,0441834 0,08804246 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,0441834 0,08797071 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,0441834 0,08789907 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,0441834 0,08782755 GO:0006740|NADPH regeneration, ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,0441834 0,08775614 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,0441834 0,08768485 ! reproductive behavior GO:0019098 22 9 0,000 0,0441834 0,08761368 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,0441834 0,08754262 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,0441834 0,08747168 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,0441834 0,08740085 ! UTP metabolic process GO:0046051 10 9 0,000 0,0441834 0,08733014 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,0441834 0,08725954 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,0441834 0,08718906 ! artery development GO:0060840 25 9 0,000 0,0441834 0,08711869 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,0441834 0,08704843 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,0441834 0,08697829 ! equilibrioception GO:0050957 20 9 0,000 0,0441834 0,08690826 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,0441834 0,08683834 ! chemosensory behavior GO:0007635 21 9 0,000 0,0441834 0,08676853 ! microtubule bundle formation GO:0001578 22 9 0,000 0,0441834 0,08669884 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,0441834 0,08662926 ! leukocyte degranulation GO:0043299 16 9 0,000 0,0441834 0,08655979 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,0441834 0,08649043 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,0441834 0,08642118 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,0441834 0,08635204 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,0441834 0,08628302 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,0441834 0,0862141 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,0441834 0,0861453 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,0441834 0,0860766 ! protein targeting to ER GO:0045047 25 9 0,000 0,0441834 0,08600801 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,0441834 0,08593953 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,0441834 0,08587117 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,0441834 0,08580291 ! glycine catabolic process GO:0006546 15 9 0,000 0,0441834 0,08573475 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,0441834 0,08566671 ! endosome organization GO:0007032 20 9 0,000 0,0441834 0,08559878 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,0441834 0,08553095 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,0441834 0,08546323 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,0441834 0,08539561 ! mannose metabolic process GO:0006013 13 9 0,000 0,0441834 0,08532811 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,0441834 0,08526071 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,0441834 0,08519341 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,0441834 0,08512623 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,0441834 0,08505915 ! receptor clustering GO:0043113 20 9 0,000 0,0441834 0,08499217 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,0441834 0,0849253 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,0441834 0,08485853 ! retinol metabolic process GO:0042572 20 9 0,000 0,0441834 0,08479187 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,0441834 0,08472532 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,0441834 0,08465887 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,0441834 0,08459252 ! macrophage differentiation GO:0030225 15 9 0,000 0,0441834 0,08452628 ! oligodendrocyte development GO:0014003 11 9 0,000 0,0441834 0,08446014 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,0441834 0,0843941 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,0441834 0,08432817 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,0441834 0,08426234 ! establishment of melanosome localization GO:0032401 14 9 0,000 0,0441834 0,08419661 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,0441834 0,08413099 ! erythrocyte development GO:0048821 17 9 0,000 0,0441834 0,08406546 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,0441834 0,08400004 ! renal water homeostasis GO:0003091 15 9 0,000 0,0441834 0,08393472 ! postreplication repair GO:0006301 25 9 0,000 0,0441834 0,08386951 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,0441834 0,08380439 ! icosanoid secretion GO:0032309 15 9 0,000 0,0441834 0,08373938 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,0441834 0,08367446 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,0441834 0,08360965 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,0441834 0,08354493 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,0441834 0,08348032 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,0441834 0,08341581 ! sterol catabolic process GO:0016127 14 9 0,000 0,0441834 0,08335139 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,0441834 0,08328708 ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,0441834 0,08322286 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,0441834 0,08315875 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,0441834 0,08309473 GO:0002820|negative regulation of adaptive immune response, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,0441834 0,08303081 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,0441834 0,08296699 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,0441834 0,08290327 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,0441834 0,08283964 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,0441834 0,08277612 ! purine base metabolic process GO:0006144 25 9 0,000 0,0441834 0,08271269 ! pigment granule transport GO:0051904 17 9 0,000 0,0441834 0,08264935 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,0441834 0,08258612 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,0441834 0,08252298 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,0441834 0,08245994 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,0441834 0,08239699 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 0,000 0,0441834 0,08233414 ! mitochondrion localization GO:0051646 18 9 0,000 0,0441834 0,08227138 ! chromosome segregation GO:0007059 127 67 1,000 0,04459754 0,08297927 ! secondary metabolic process GO:0019748 125 67 1,000 0,04459754 0,08291612 ! myeloid cell differentiation GO:0030099 126 67 1,000 0,04459754 0,08285307 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,04580126 0,08502468 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! detection of external stimulus GO:0009581 102 68 1,000 0,04580126 0,08496012 ! viral reproduction GO:0016032 142 68 1,000 0,04580126 0,08489566 ! regulation of lipase activity GO:0060191 137 68 1,000 0,04580126 0,0848313 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,04580126 0,08476703 ! lung development GO:0030324 165 69 1,000 0,04701689 0,08695099 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,04701689 0,08688522 ! urogenital system development GO:0001655 149 69 1,000 0,04701689 0,08681955 ! germ cell development GO:0007281 133 70 1,000 0,04824427 0,0890187 ! activation of immune response GO:0002253 120 70 1,000 0,04824427 0,08895152 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,04897123 0,09022376 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,04897123 0,09015577 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04897123 0,09008789 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,04897123 0,0900201 ! associative learning GO:0008306 21 10 0,000 0,04897123 0,08995241 ! positive regulation of B cell proliferation GO:0030890 18 10 0,000 0,04897123 0,08988483 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04897123 0,08981735 ! phosphate transport GO:0006817 24 10 0,000 0,04897123 0,08974997 ! cell volume homeostasis GO:0006884 17 10 0,000 0,04897123 0,08968269 ! CTP metabolic process GO:0046036 11 10 0,000 0,04897123 0,08961551 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! GTP metabolic process GO:0046039 11 10 0,000 0,04897123 0,08954844 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,04897123 0,08948146 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,04897123 0,08941458 ! social behavior GO:0035176 29 10 0,000 0,04897123 0,08934781 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,04897123 0,08928113 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,04897123 0,08921455 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,04897123 0,08914807 ! androgen metabolic process GO:0008209 17 10 0,000 0,04897123 0,08908169 ! phospholipid efflux GO:0033700 19 10 0,000 0,04897123 0,08901541 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04897123 0,08894923 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,04897123 0,08888314 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,04897123 0,08881716 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,04897123 0,08875127 ! pathogenesis GO:0009405 17 10 0,000 0,04897123 0,08868548 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04897123 0,08861979 ! negative regulation of striated muscle development GO:0045843 26 10 0,000 0,04897123 0,08855419 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,04897123 0,08848869 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,04897123 0,08842329 ! endoderm development GO:0007492 18 10 0,000 0,04897123 0,08835799 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,04897123 0,08829278 ! arginine catabolic process GO:0006527 17 10 0,000 0,04897123 0,08822766 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04897123 0,08816265 ! proline metabolic process GO:0006560 13 10 0,000 0,04897123 0,08809773 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04897123 0,0880329 GO:0005978|glycogen biosynthetic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,04897123 0,08796817 ! V(D)J recombination GO:0033151 34 10 0,000 0,04897123 0,08790354 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,04897123 0,087839 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,04897123 0,08777455 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,04897123 0,0877102 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,04897123 0,08764594 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,04897123 0,08758178 ! multicellular organism growth GO:0035264 19 10 0,000 0,04897123 0,08751771 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,04897123 0,08745374 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,04897123 0,08738986 ! ruffle organization GO:0031529 17 10 0,000 0,04897123 0,08732607 ! epithelial cell development GO:0002064 21 10 0,000 0,04897123 0,08726237 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,04897123 0,08719877 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04897123 0,08713526 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,04897123 0,08707184 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,04897123 0,08700852 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 0,000 0,04897123 0,08694528 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,04897123 0,08688214 GO:0030204|chondroitin sulfate metabolic process, ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 0,000 0,04897123 0,08681909 ! copper ion homeostasis GO:0055070 13 10 0,000 0,04897123 0,08675614 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04897123 0,08669327 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04897123 0,08663049 ! segment specification GO:0007379 15 10 0,000 0,04897123 0,08656781 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,04897123 0,08650521 ! blastoderm segmentation GO:0007350 19 10 0,000 0,04897123 0,08644271 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,04897123 0,0863803 ! DNA ligation GO:0006266 18 10 0,000 0,04897123 0,08631797 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,04897123 0,08625574 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04897123 0,0861936 ! melanosome localization GO:0032400 16 10 0,000 0,04897123 0,08613154 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,04897123 0,08606958 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,04897123 0,0860077 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,04897123 0,08594591 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04897123 0,08588422 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,04897123 0,08582261 ! induction of an organ GO:0001759 17 10 0,000 0,04897123 0,08576108 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,04897123 0,08569965 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,04897123 0,0856383 ! protein sumoylation GO:0016925 17 10 0,000 0,04897123 0,08557705 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,04897123 0,08551588 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04897123 0,08545479 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04897123 0,0853938 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,04897123 0,08533289 ! salivary gland development GO:0007431 28 10 0,000 0,04897123 0,08527207 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,04897123 0,08521133 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,04897123 0,08515068 ! midbrain development GO:0030901 14 10 0,000 0,04897123 0,08509012 ! musculoskeletal movement GO:0050881 16 10 0,000 0,04897123 0,08502965 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,04897123 0,08496926 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,04897123 0,08490895 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,04897123 0,08484873 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,04897123 0,0847886 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,04897123 0,08472855 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04897123 0,08466859 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,04897123 0,08460871 ! detection of calcium ion GO:0005513 24 10 0,000 0,04897123 0,08454891 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04897123 0,0844892 ! blastocyst formation GO:0001825 18 10 0,000 0,04897123 0,08442958 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,04897123 0,08437004 ! cerebellar cortex development GO:0021695 16 10 0,000 0,04897123 0,08431058 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,04897123 0,08425121 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,04897123 0,08419192 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,04897123 0,08413271 ! respiratory tube development GO:0030323 171 72 1,000 0,05073373 0,08709944 ! B cell activation GO:0042113 179 72 1,000 0,05073373 0,08703827 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,05073373 0,08697719 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,05073373 0,0869162 ! humoral immune response GO:0006959 115 73 1,000 0,05199551 0,08901544 ! amino acid transport GO:0006865 148 74 1,000 0,05326847 0,09113086 ! respiratory system development GO:0060541 175 74 1,000 0,05326847 0,09106708 ! organelle localization GO:0051640 155 74 1,000 0,05326847 0,0910034 ! negative regulation of muscle development GO:0048635 27 11 0,000 0,0537352 0,09173662 ! respiratory burst GO:0045730 17 11 0,000 0,0537352 0,09167256 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,0537352 0,09160859 ! neuron fate specification GO:0048665 18 11 0,000 0,0537352 0,0915447 ! telencephalon cell migration GO:0022029 23 11 0,000 0,0537352 0,09148091 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,0537352 0,0914172 ! thyroid gland development GO:0030878 26 11 0,000 0,0537352 0,09135359 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 0,000 0,0537352 0,09129006 ! synapsis GO:0007129 14 11 0,000 0,0537352 0,09122662 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,0537352 0,09116327 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,0537352 0,0911 ! response to pain GO:0048265 27 11 0,000 0,0537352 0,09103683 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,0537352 0,09097374 ! bone resorption GO:0045453 16 11 0,000 0,0537352 0,09091074 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,0537352 0,09084782 ! peptide or protein amino-terminal blocking GO:0018409 22 11 0,000 0,0537352 0,090785 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,0537352 0,09072226 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,0537352 0,0906596 ! melanocyte differentiation GO:0030318 20 11 0,000 0,0537352 0,09059704 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,0537352 0,09053456 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,0537352 0,09047216 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,0537352 0,09040985 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,0537352 0,09034763 ! regulation of intracellular pH GO:0051453 21 11 0,000 0,0537352 0,09028549 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,0537352 0,09022344 ! UV protection GO:0009650 20 11 0,000 0,0537352 0,09016147 ! adult heart development GO:0007512 16 11 0,000 0,0537352 0,09009959 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,0537352 0,09003779 ! macroautophagy GO:0016236 19 11 0,000 0,0537352 0,08997608 ! temperature homeostasis GO:0001659 18 11 0,000 0,0537352 0,08991446 ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,0537352 0,08985291 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 0,000 0,0537352 0,08979145 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,0537352 0,08973008 ! negative regulation of axonogenesis GO:0050771 37 11 0,000 0,0537352 0,08966879 ! regulation of organ growth GO:0046620 14 11 0,000 0,0537352 0,08960758 ! pigment granule localization GO:0051875 20 11 0,000 0,0537352 0,08954646 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,0537352 0,08948542 ! vasoconstriction GO:0042310 20 11 0,000 0,0537352 0,08942446 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,0537352 0,08936358 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,0537352 0,08930279 ! embryonic axis specification GO:0000578 19 11 0,000 0,0537352 0,08924208 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,0537352 0,08918146 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,0537352 0,08912091 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,0537352 0,08906045 ! nitric oxide metabolic process GO:0046209 17 11 0,000 0,0537352 0,08900007 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,0537352 0,08893977 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,0537352 0,08887956 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,0537352 0,08881942 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,0537352 0,08875937 ! prophase GO:0051324 17 11 0,000 0,0537352 0,0886994 ! neuroblast proliferation GO:0007405 25 11 0,000 0,0537352 0,0886395 ! nucleosome positioning GO:0016584 15 11 0,000 0,0537352 0,08857969 ! regulation of isotype switching GO:0045191 24 11 0,000 0,0537352 0,08851996 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,0537352 0,08846031 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,0537352 0,08840074 ! apical protein localization GO:0045176 18 11 0,000 0,0537352 0,08834126 ! acid secretion GO:0046717 20 11 0,000 0,0537352 0,08828185 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,0537352 0,08822252 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,0537352 0,08816327 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,0537352 0,0881041 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,0537352 0,08804501 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,0537352 0,087986 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 21 11 0,000 0,0537352 0,08792706 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,0537352 0,08786821 ! germ cell migration GO:0008354 26 11 0,000 0,0537352 0,08780943 ! embryonic gut development GO:0048566 19 11 0,000 0,0537352 0,08775074 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,0537352 0,08769212 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,0537352 0,08763358 ! activation of innate immune response GO:0002218 16 11 0,000 0,0537352 0,08757512 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,0537352 0,08751674 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,0537352 0,08745843 ! lysogeny GO:0030069 22 11 0,000 0,0537352 0,0874002 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,0537352 0,08734205 ! sequestering of metal ion GO:0051238 15 11 0,000 0,0537352 0,08728398 ! nucleus localization GO:0051647 22 11 0,000 0,0537352 0,08722598 ! regulation of transcription factor activity GO:0051090 137 75 1,000 0,05455246 0,0884938 GO:0090046|regulation of transcription regulator activity, ! reproductive structure development GO:0048608 131 75 1,000 0,05455246 0,08843507 ! axon guidance GO:0007411 162 75 1,000 0,05455246 0,08837643 ! rhythmic process GO:0048511 142 75 1,000 0,05455246 0,08831786 ! lymphocyte differentiation GO:0030098 193 76 1,000 0,05584734 0,09035435 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,05715298 0,09240552 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,05847545 0,09448117 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,05847545 0,09441872 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,05847545 0,09435636 ! mating GO:0007618 17 12 0,000 0,05847545 0,09429408 ! protein complex disassembly GO:0043241 28 12 0,000 0,05847545 0,09423188 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05847545 0,09416976 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,05847545 0,09410772 ! hippocampus development GO:0021766 29 12 0,000 0,05847545 0,09404577 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,05847545 0,0939839 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,05847545 0,09392211 ! T cell proliferation GO:0042098 32 12 0,000 0,05847545 0,0938604 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05847545 0,09379877 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,05847545 0,09373722 ! ventral spinal cord development GO:0021517 25 12 0,000 0,05847545 0,09367575 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,05847545 0,09361437 ! drug transport GO:0015893 16 12 0,000 0,05847545 0,09355306 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,05847545 0,09349184 ! tyrosine metabolic process GO:0006570 19 12 0,000 0,05847545 0,09343069 ! polyamine metabolic process GO:0006595 18 12 0,000 0,05847545 0,09336962 ! mitotic spindle organization GO:0007052 23 12 0,000 0,05847545 0,09330864 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,05847545 0,09324773 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,05847545 0,0931869 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,05847545 0,09312616 ! lipid digestion GO:0044241 21 12 0,000 0,05847545 0,09306549 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,05847545 0,0930049 ! entry into host cell GO:0030260 34 12 0,000 0,05847545 0,09294439 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05847545 0,09288396 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,05847545 0,0928236 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,05847545 0,09276333 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05847545 0,09270313 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,05847545 0,09264301 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,05847545 0,09258297 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,05847545 0,09252301 ! snRNA metabolic process GO:0016073 30 12 0,000 0,05847545 0,09246312 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,05847545 0,09240331 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,05847545 0,09234358 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05847545 0,09228393 ! cranial nerve development GO:0021545 23 12 0,000 0,05847545 0,09222435 ! fucose catabolic process GO:0019317 25 12 0,000 0,05847545 0,09216485 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,05847545 0,09210543 ! histone acetylation GO:0016573 27 12 0,000 0,05847545 0,09204609 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,05847545 0,09198682 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05847545 0,09192762 ! zymogen activation GO:0031638 18 12 0,000 0,05847545 0,0918685 ! peptidyl-lysine modification GO:0018205 21 12 0,000 0,05847545 0,09180946 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,05847545 0,0917505 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,05847545 0,09169161 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,05847545 0,09163279 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,05847545 0,09157405 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,05847545 0,09151539 ! defense response to fungus GO:0050832 15 12 0,000 0,05847545 0,0914568 ! developmental induction GO:0031128 22 12 0,000 0,05847545 0,09139829 GO:0045168|cell-cell signaling involved in cell fate specification, ! embryonic placenta development GO:0001892 21 12 0,000 0,05847545 0,09133985 ! lamellipodium assembly GO:0030032 24 12 0,000 0,05847545 0,09128149 ! response to cold GO:0009409 17 12 0,000 0,05847545 0,0912232 ! establishment of cell polarity GO:0030010 21 12 0,000 0,05847545 0,09116498 ! regulation of synapse organization GO:0050807 18 12 0,000 0,05847545 0,09110684 ! localization within membrane GO:0051668 26 12 0,000 0,05847545 0,09104877 ! blood coagulation GO:0007596 151 79 1,000 0,05979597 0,09304558 GO:0050817|coagulation, ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 1,000 0,06113305 0,09506558 ! activation of protein kinase activity GO:0032147 170 80 1,000 0,06113305 0,09500511 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,06113305 0,09494471 ! negative regulation of organelle organization GO:0010639 181 80 1,000 0,06113305 0,09488439 ! meiosis GO:0007126 143 81 1,000 0,06248033 0,09691393 GO:0051327|M phase of meiotic cell cycle, ! negative regulation of cell projection organization GO:0031345 42 13 0,000 0,06319208 0,09795575 ! cGMP metabolic process GO:0046068 18 13 0,000 0,06319208 0,09789363 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,06319208 0,09783159 ! regulation of chemokine production GO:0032642 18 13 0,000 0,06319208 0,09776964 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,06319208 0,09770776 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,06319208 0,09764596 ! peroxisomal transport GO:0043574 28 13 0,000 0,06319208 0,09758423 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,06319208 0,09752259 ! cartilage condensation GO:0001502 22 13 0,000 0,06319208 0,09746102 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,06319208 0,09739953 ! organelle fusion GO:0048284 36 13 0,000 0,06319208 0,09733812 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,06319208 0,09727678 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,06319208 0,09721553 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,06319208 0,09715435 ! endocrine pancreas development GO:0031018 25 13 0,000 0,06319208 0,09709324 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,06319208 0,09703222 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,06319208 0,09697127 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,06319208 0,09691039 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 0,000 0,06319208 0,0968496 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,06319208 0,09678888 ! methionine metabolic process GO:0006555 31 13 0,000 0,06319208 0,09672823 ! plasma membrane organization GO:0007009 27 13 0,000 0,06319208 0,09666766 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,06319208 0,09660717 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,06319208 0,09654675 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,06319208 0,09648641 ! response to X-ray GO:0010165 28 13 0,000 0,06319208 0,09642614 ! cytokine metabolic process GO:0042107 24 13 0,000 0,06319208 0,09636595 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,06319208 0,09630584 ! exocrine system development GO:0035272 34 13 0,000 0,06319208 0,0962458 ! asymmetric protein localization GO:0008105 24 13 0,000 0,06319208 0,09618583 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,06319208 0,09612594 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,06319208 0,09606612 ! L-glutamate transport GO:0015813 30 13 0,000 0,06319208 0,09600638 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,06319208 0,09594671 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,06319208 0,09588712 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,06319208 0,0958276 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,06319208 0,09576815 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,06319208 0,09570878 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,06319208 0,09564948 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,06319208 0,09559025 ! regulation of monooxygenase activity GO:0032768 35 13 0,000 0,06319208 0,0955311 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,06319208 0,09547202 ! histone methylation GO:0016571 29 13 0,000 0,06319208 0,09541301 ! chromatin silencing GO:0006342 29 13 0,000 0,06319208 0,09535408 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,06319208 0,09529522 ! regulation of erythrocyte differentiation GO:0045646 47 13 0,000 0,06319208 0,09523643 ! regulation of epidermis development GO:0045682 19 13 0,000 0,06319208 0,09517772 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,06319208 0,09511907 ! aromatic amino acid family catabolic process GO:0009074 20 13 0,000 0,06319208 0,0950605 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,06319208 0,095002 ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,06319208 0,09494358 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,06319208 0,09488522 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,06319208 0,09482694 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,06319208 0,09476873 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,06319208 0,09471059 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,06319208 0,09465252 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,06319208 0,09459452 ! insulin secretion GO:0030073 24 13 0,000 0,06319208 0,09453659 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,06319208 0,09447874 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,06319208 0,09442095 ! acrosome reaction GO:0007340 19 13 0,000 0,06319208 0,09436324 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,06319208 0,09430559 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,06319208 0,09424802 ! protein import into nucleus GO:0006606 174 82 1,000 0,06383768 0,0951528 ! meiotic cell cycle GO:0051321 144 82 1,000 0,06383768 0,09509478 ! cellular lipid catabolic process GO:0044242 150 83 1,000 0,06520496 0,09707235 ! nuclear import GO:0051170 177 83 1,000 0,06520496 0,09701323 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,06788522 0,10093949 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,06788522 0,10087809 ! water transport GO:0006833 21 14 0,000 0,06788522 0,10081677 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,06788522 0,10075552 ! non-recombinational repair GO:0000726 29 14 0,000 0,06788522 0,10069435 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,06788522 0,10063324 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,06788522 0,10057222 ! RNA polyadenylation GO:0043631 32 14 0,000 0,06788522 0,10051126 ! lipid localization GO:0010876 32 14 0,000 0,06788522 0,10045039 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,06788522 0,10038958 ! regulated secretory pathway GO:0045055 24 14 0,000 0,06788522 0,10032885 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,06788522 0,10026819 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,06788522 0,10020761 ! arginine metabolic process GO:0006525 21 14 0,000 0,06788522 0,10014709 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,06788522 0,10008665 ! cell-cell junction assembly GO:0007043 32 14 0,000 0,06788522 0,10002629 ! regulation of heart rate GO:0002027 25 14 0,000 0,06788522 0,099966 ! organic alcohol transport GO:0015850 29 14 0,000 0,06788522 0,09990578 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,06788522 0,09984563 ! embryo implantation GO:0007566 30 14 0,000 0,06788522 0,09978555 ! neutral amino acid transport GO:0015804 28 14 0,000 0,06788522 0,09972555 ! bone mineralization GO:0030282 18 14 0,000 0,06788522 0,09966562 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,06788522 0,09960576 ! negative regulation of protein import into nucleus GO:0042308 33 14 0,000 0,06788522 0,09954597 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,06788522 0,09948626 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,06788522 0,09942661 ! regulation of cellular pH GO:0030641 27 14 0,000 0,06788522 0,09936704 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,06788522 0,09930754 ! ribosome assembly GO:0042255 18 14 0,000 0,06788522 0,09924811 ! cerebellum development GO:0021549 23 14 0,000 0,06788522 0,09918875 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,06788522 0,09912946 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,06788522 0,09907024 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,06788522 0,0990111 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,06788522 0,09895202 ! NADP metabolic process GO:0006739 24 14 0,000 0,06788522 0,09889302 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,06788522 0,09883408 ! oxygen transport GO:0015671 22 14 0,000 0,06788522 0,09877522 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,06788522 0,09871642 ! male genitalia development GO:0030539 26 14 0,000 0,06788522 0,0986577 ! regulation of axon extension GO:0030516 43 14 0,000 0,06788522 0,09859904 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,06788522 0,09854046 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,06788522 0,09848194 ! hemostasis GO:0007599 165 85 1,000 0,06796882 0,09854471 ! regulation of neuron differentiation GO:0045664 187 85 1,000 0,06796882 0,09848626 ! lactation GO:0007595 30 15 0,000 0,07255497 0,10506924 ! N-terminal protein amino acid modification GO:0031365 30 15 0,000 0,07255497 0,10500699 ! reproductive cellular process GO:0048610 22 15 0,000 0,07255497 0,10494482 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,07255497 0,10488272 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,07255497 0,1048207 ! superoxide anion generation GO:0042554 22 15 0,000 0,07255497 0,10475875 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,07255497 0,10469687 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,07255497 0,10463507 ! copper ion transport GO:0006825 22 15 0,000 0,07255497 0,10457333 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,07255497 0,10451168 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,07255497 0,10445009 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,07255497 0,10438858 ! sulfate transport GO:0008272 27 15 0,000 0,07255497 0,10432713 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,07255497 0,10426577 ! regulation of mRNA processing GO:0050684 26 15 0,000 0,07255497 0,10420447 ! response to hexose stimulus GO:0009746 25 15 0,000 0,07255497 0,10414324 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,07255497 0,10408209 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,07255497 0,10402101 ! vesicle coating GO:0006901 38 15 0,000 0,07255497 0,10396 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,07255497 0,10389906 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 0,000 0,07255497 0,1038382 ! regulation of exocytosis GO:0017157 26 15 0,000 0,07255497 0,1037774 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,07255497 0,10371668 ! G1/S transition checkpoint GO:0031575 37 15 0,000 0,07255497 0,10365602 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,07255497 0,10359544 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,07255497 0,10353493 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,07255497 0,10347449 ! regulation of vasodilation GO:0042312 27 15 0,000 0,07255497 0,10341412 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,07255497 0,10335382 ! histone deacetylation GO:0016575 24 15 0,000 0,07255497 0,10329359 ! water homeostasis GO:0030104 28 15 0,000 0,07255497 0,10323343 ! cofactor transport GO:0051181 30 15 0,000 0,07255497 0,10317334 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,07255497 0,10311332 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,07255497 0,10305337 ! intestinal absorption GO:0050892 31 15 0,000 0,07255497 0,10299349 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,07255497 0,10293368 ! heme biosynthetic process GO:0006783 33 15 0,000 0,07255497 0,10287394 ! cell killing GO:0001906 32 15 0,000 0,07255497 0,10281427 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,07255497 0,10275467 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,07255497 0,10269513 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,07255497 0,10263567 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,07255497 0,10257627 ! regulation of DNA binding GO:0051101 167 89 1,000 0,07361005 0,10400772 ! tube morphogenesis GO:0035239 194 89 1,000 0,07361005 0,1039476 ! protein localization in nucleus GO:0034504 192 89 1,000 0,07361005 0,10388755 ! response to unfolded protein GO:0006986 139 90 1,000 0,07504325 0,10584912 ! regulation of protein ubiquitination GO:0031396 28 16 0,000 0,07720147 0,10883046 ! positive regulation of cell size GO:0045793 29 16 0,000 0,07720147 0,10876769 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,07720147 0,108705 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,07720147 0,10864239 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,07720147 0,10857984 ! bone remodeling GO:0046849 28 16 0,000 0,07720147 0,10851737 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 0,000 0,07720147 0,10845496 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,07720147 0,10839263 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,07720147 0,10833037 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,07720147 0,10826819 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,07720147 0,10820607 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,07720147 0,10814403 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,07720147 0,10808205 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,07720147 0,10802015 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 0,000 0,07720147 0,10795832 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,07720147 0,10789656 ! protein polyubiquitination GO:0000209 41 16 0,000 0,07720147 0,10783487 ! glutamate metabolic process GO:0006536 25 16 0,000 0,07720147 0,10777325 ! pituitary gland development GO:0021983 30 16 0,000 0,07720147 0,1077117 ! response to osmotic stress GO:0006970 27 16 0,000 0,07720147 0,10765022 ! lysosomal transport GO:0007041 31 16 0,000 0,07720147 0,10758881 ! L-amino acid transport GO:0015807 33 16 0,000 0,07720147 0,10752747 ! stem cell development GO:0048864 46 16 0,000 0,07720147 0,1074662 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07720147 0,107405 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,07720147 0,10734387 ! intermediate filament-based process GO:0045103 36 16 0,000 0,07720147 0,10728281 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,07720147 0,10722182 ! negative regulation of immune response GO:0050777 38 16 0,000 0,07720147 0,1071609 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,07720147 0,10710005 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,07720147 0,10703926 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,07720147 0,10697855 ! DNA replication initiation GO:0006270 28 16 0,000 0,07720147 0,1069179 ! neuron recognition GO:0008038 40 16 0,000 0,07720147 0,10685733 ! mRNA splice site selection GO:0006376 44 16 0,000 0,07720147 0,10679682 ! tissue regeneration GO:0042246 27 16 0,000 0,07720147 0,10673638 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,07720147 0,10667601 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,07720147 0,1066157 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,07720147 0,10655547 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,07720147 0,1064953 ! regulation of T-helper cell differentiation GO:0045622 30 16 0,000 0,07720147 0,1064352 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07720147 0,10637517 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,07720147 0,10631521 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,07720147 0,10625531 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,07720147 0,10619548 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,07720147 0,10613572 ! peptide hormone processing GO:0016486 27 16 0,000 0,07720147 0,10607603 ! regulation of cell morphogenesis GO:0022604 243 93 1,000 0,07939583 0,1090298 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,07939583 0,10896855 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 1,000 0,07939583 0,10890736 ! female pregnancy GO:0007565 166 94 1,000 0,08086393 0,11085892 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,08182481 0,1121133 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,08182481 0,11205045 ! embryonic forelimb morphogenesis GO:0035115 31 17 0,000 0,08182481 0,11198768 ! filopodium assembly GO:0046847 42 17 0,000 0,08182481 0,11192498 ! endothelial cell migration GO:0043542 31 17 0,000 0,08182481 0,11186234 ! gene silencing by RNA GO:0031047 38 17 0,000 0,08182481 0,11179978 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,08182481 0,11173729 ! glial cell development GO:0021782 28 17 0,000 0,08182481 0,11167487 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,08182481 0,11161251 ! auditory receptor cell differentiation GO:0042491 36 17 0,000 0,08182481 0,11155023 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,08182481 0,11148801 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,08182481 0,11142587 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,08182481 0,11136379 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,08182481 0,11130179 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,08182481 0,11123985 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,08182481 0,11117798 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,08182481 0,11111618 ! negative regulation of microtubule depolymerization GO:0007026 50 17 0,000 0,08182481 0,11105445 GO:0031114|regulation of microtubule depolymerization, ! NAD metabolic process GO:0019674 33 17 0,000 0,08182481 0,11099279 ! membrane budding GO:0006900 42 17 0,000 0,08182481 0,11093119 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,08182481 0,11086967 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,08182481 0,11080821 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,08182481 0,11074682 ! genitalia development GO:0048806 32 17 0,000 0,08182481 0,1106855 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 0,000 0,08182481 0,11062424 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,08182481 0,11056306 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,08182481 0,11050194 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,08182481 0,11044089 ! steroid catabolic process GO:0006706 34 17 0,000 0,08182481 0,11037991 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,08182481 0,11031899 ! gas transport GO:0015669 26 17 0,000 0,08182481 0,11025814 ! organic cation transport GO:0015695 32 17 0,000 0,08182481 0,11019736 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,08182481 0,11013664 ! sex differentiation GO:0007548 171 96 1,000 0,08382527 0,11276715 ! biogenic amine metabolic process GO:0006576 162 97 1,000 0,08531827 0,11471246 ! transcription initiation GO:0006352 171 97 1,000 0,08531827 0,11464936 ! regulation of protein localization GO:0032880 188 97 1,000 0,08531827 0,11458633 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,08642512 0,1160091 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,08642512 0,11594539 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,08642512 0,11588176 ! limbic system development GO:0021761 40 18 0,000 0,08642512 0,11581819 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,08642512 0,1157547 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,08642512 0,11569127 ! adult walking behavior GO:0007628 36 18 0,000 0,08642512 0,11562791 ! patterning of blood vessels GO:0001569 43 18 0,000 0,08642512 0,11556462 ! heart looping GO:0001947 34 18 0,000 0,08642512 0,1155014 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,08642512 0,11543825 ! centrosome cycle GO:0007098 26 18 0,000 0,08642512 0,11537517 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,08642512 0,11531216 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,08642512 0,11524922 ! glycine metabolic process GO:0006544 30 18 0,000 0,08642512 0,11518634 ! glutamine metabolic process GO:0006541 29 18 0,000 0,08642512 0,11512354 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,08642512 0,1150608 ! DNA integration GO:0015074 32 18 0,000 0,08642512 0,11499813 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,08642512 0,11493553 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,08642512 0,11487299 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,08642512 0,11481053 ! neural crest cell migration GO:0001755 41 18 0,000 0,08642512 0,11474813 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,08642512 0,1146858 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,08642512 0,11462354 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,08642512 0,11456135 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,08642512 0,11449922 GO:0033014|tetrapyrrole biosynthetic process, ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,08642512 0,11443716 ! detection of bacterium GO:0016045 22 18 0,000 0,08642512 0,11437517 ! nerve development GO:0021675 34 18 0,000 0,08642512 0,11431325 ! microspike assembly GO:0030035 46 18 0,000 0,08642512 0,11425139 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,08642512 0,1141896 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 0,000 0,08642512 0,11412787 ! leukocyte differentiation GO:0002521 232 98 1,000 0,08681933 0,11458651 ! forebrain development GO:0030900 210 98 1,000 0,08681933 0,11452464 ! regulation of nucleotide metabolic process GO:0006140 197 98 1,000 0,08681933 0,11446284 ! positive regulation of immune response GO:0050778 175 100 1,000 0,08984518 0,11838822 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,09100251 0,11984859 ! positive regulation of translation GO:0045727 31 19 0,000 0,09100251 0,11978401 ! negative regulation of defense response GO:0031348 27 19 0,000 0,09100251 0,11971951 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,09100251 0,11965507 ! neuron maturation GO:0042551 46 19 0,000 0,09100251 0,11959071 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,09100251 0,11952641 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,09100251 0,11946218 GO:0019692|deoxyribose phosphate metabolic process, ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,09100251 0,11939803 ! inositol metabolic process GO:0006020 33 19 0,000 0,09100251 0,11933394 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,09100251 0,11926992 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,09100251 0,11920597 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,09100251 0,11914208 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 0,000 0,09100251 0,11907827 ! cerebral cortex development GO:0021987 40 19 0,000 0,09100251 0,11901452 ! heme metabolic process GO:0042168 40 19 0,000 0,09100251 0,11895084 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,09100251 0,11888723 ! response to fungus GO:0009620 26 19 0,000 0,09100251 0,11882369 ! peptide cross-linking GO:0018149 39 19 0,000 0,09100251 0,11876022 ! protein export from nucleus GO:0006611 40 19 0,000 0,09100251 0,11869681 ! heart process GO:0003015 32 19 0,000 0,09100251 0,11863347 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,09100251 0,1185702 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,09100251 0,118507 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,09100251 0,11844386 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,09100251 0,11838079 ! vitamin transport GO:0051180 31 19 0,000 0,09100251 0,11831779 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,09100251 0,11825485 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,09100251 0,11819199 ! proximal/distal pattern formation GO:0009954 33 19 0,000 0,09100251 0,11812918 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,09100251 0,11806645 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,09100251 0,11800378 ! cilium assembly GO:0042384 38 19 0,000 0,09100251 0,11794118 ! peptide hormone secretion GO:0030072 32 19 0,000 0,09100251 0,11787865 ! protein secretion GO:0009306 45 20 0,000 0,09555709 0,12371276 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,09555709 0,12364723 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,09555709 0,12358177 ! positive regulation of ossification GO:0045778 50 20 0,000 0,09555709 0,12351639 ! positive regulation of angiogenesis GO:0045766 50 20 0,000 0,09555709 0,12345107 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,09555709 0,12338582 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,09555709 0,12332064 ! protein amino acid deacetylation GO:0006476 34 20 0,000 0,09555709 0,12325553 ! protein amino acid acetylation GO:0006473 41 20 0,000 0,09555709 0,12319049 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 0,000 0,09555709 0,12312551 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,09555709 0,12306061 ! forelimb morphogenesis GO:0035136 35 20 0,000 0,09555709 0,12299577 ! bile acid metabolic process GO:0008206 34 20 0,000 0,09555709 0,122931 ! retinoid metabolic process GO:0001523 34 20 0,000 0,09555709 0,1228663 GO:0016101|diterpenoid metabolic process, ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,09555709 0,12280167 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,09555709 0,1227371 GO:0032392|DNA geometric change, ! actin filament bundle formation GO:0051017 47 20 0,000 0,09555709 0,12267261 ! body fluid secretion GO:0007589 33 20 0,000 0,09555709 0,12260818 ! peptide secretion GO:0002790 38 20 0,000 0,09555709 0,12254382 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,09555709 0,12247952 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,09555709 0,1224153 ! regulation of interleukin-2 production GO:0032663 39 20 0,000 0,09555709 0,12235114 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,09555709 0,12228705 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,09555709 0,12222302 ! cell-cell junction organization GO:0045216 43 20 0,000 0,09555709 0,12215906 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,09555709 0,12209517 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,09555709 0,12203135 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,09555709 0,12196759 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,09555709 0,1219039 ! aromatic compound catabolic process GO:0019439 31 20 0,000 0,09555709 0,12184028 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,09555709 0,12177672 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,09555709 0,12171323 ! regulation of cell killing GO:0031341 46 21 0,000 0,10008898 0,12741916 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,10008898 0,1273528 ! hormone secretion GO:0046879 39 21 0,000 0,10008898 0,12728651 ! lipid phosphorylation GO:0046834 43 21 0,000 0,10008898 0,12722028 ! cAMP metabolic process GO:0046058 41 21 0,000 0,10008898 0,12715412 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,10008898 0,12708803 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,10008898 0,12702201 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,10008898 0,12695606 ! smooth muscle contraction GO:0006939 48 21 0,000 0,10008898 0,12689018 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,10008898 0,12682437 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,10008898 0,12675862 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,10008898 0,12669294 ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,10008898 0,12662733 ! sensory perception of pain GO:0019233 33 21 0,000 0,10008898 0,12656179 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,10008898 0,12649632 ! diencephalon development GO:0021536 36 21 0,000 0,10008898 0,12643091 ! negative regulation of intracellular transport GO:0032387 44 21 0,000 0,10008898 0,12636557 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,10008898 0,1263003 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,10008898 0,12623509 ! collagen catabolic process GO:0030574 29 21 0,000 0,10008898 0,12616996 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,10008898 0,12610489 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,10008898 0,12603989 ! sperm-egg recognition GO:0035036 23 21 0,000 0,10008898 0,12597495 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 0,000 0,10008898 0,12591008 ! positive regulation of protein catabolic process GO:0045732 44 22 0,000 0,10459829 0,13151499 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,10459829 0,13144733 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,10459829 0,13137975 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,10459829 0,13131224 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,10459829 0,1312448 GO:0034105|positive regulation of tissue remodeling, ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 0,000 0,10459829 0,13117742 ! hindlimb morphogenesis GO:0035137 47 22 0,000 0,10459829 0,13111012 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 0,000 0,10459829 0,13104288 ! cellular response to starvation GO:0009267 37 22 0,000 0,10459829 0,13097571 ! vacuolar transport GO:0007034 41 22 0,000 0,10459829 0,13090862 ! central nervous system neuron development GO:0021954 47 22 0,000 0,10459829 0,13084159 ! fucose metabolic process GO:0006004 44 22 0,000 0,10459829 0,13077463 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,10459829 0,13070773 ! stem cell differentiation GO:0048863 57 22 0,000 0,10459829 0,13064091 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 0,000 0,10459829 0,13057415 ! cytolysis GO:0019835 27 22 0,000 0,10459829 0,13050747 ! vasodilation GO:0042311 40 22 0,000 0,10459829 0,13044085 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,10459829 0,13037429 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,10459829 0,13030781 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,10459829 0,1302414 ! positive regulation of intracellular transport GO:0032388 42 22 0,000 0,10459829 0,13017505 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,10459829 0,13010877 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,10459829 0,13004255 ! sarcomere organization GO:0045214 32 22 0,000 0,10459829 0,12997641 ! positive regulation of B cell activation GO:0050871 42 22 0,000 0,10459829 0,12991033 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,10459829 0,12984432 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,10459829 0,12977837 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,10459829 0,1297125 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,10459829 0,12964669 ! inner ear receptor cell differentiation GO:0060113 42 22 0,000 0,10459829 0,12958094 ! protein stabilization GO:0050821 41 22 0,000 0,10459829 0,12951526 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,10908513 0,13500252 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,10908513 0,13493416 ! gluconeogenesis GO:0006094 38 23 0,000 0,10908513 0,13486587 ! viral genome replication GO:0019079 44 23 0,000 0,10908513 0,13479766 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,10908513 0,13472951 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,10908513 0,13466143 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,10908513 0,13459342 ! axis specification GO:0009798 43 23 0,000 0,10908513 0,13452547 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,10908513 0,1344576 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,10908513 0,1343898 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,10908513 0,13432206 ! peroxisome organization GO:0007031 43 23 0,000 0,10908513 0,13425439 ! lysosome organization GO:0007040 47 23 0,000 0,10908513 0,13418679 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,10908513 0,13411926 ! vesicle targeting GO:0006903 49 23 0,000 0,10908513 0,13405179 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 0,000 0,10908513 0,1339844 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,10908513 0,13391707 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,10908513 0,13384981 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,10908513 0,13378261 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,10908513 0,13371549 ! DNA modification GO:0006304 36 23 0,000 0,10908513 0,13364843 ! fatty acid transport GO:0015908 47 23 0,000 0,10908513 0,13358144 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 0,000 0,10908513 0,13351451 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,10908513 0,13344765 ! nerve-nerve synaptic transmission GO:0007270 59 23 0,000 0,10908513 0,13338086 ! hormone transport GO:0009914 41 23 0,000 0,10908513 0,13331414 ! cell-cell recognition GO:0009988 28 23 0,000 0,10908513 0,13324748 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,10908513 0,13318089 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,10908513 0,13311437 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,10908513 0,13304791 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,11354961 0,138424 GO:0016444|somatic cell DNA recombination, ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,11354961 0,13835496 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,11354961 0,13828599 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,11354961 0,13821709 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,11354961 0,13814825 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,11354961 0,13807949 ! mechanoreceptor differentiation GO:0042490 48 24 0,000 0,11354961 0,13801079 ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,11354961 0,13794217 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,11354961 0,13787361 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,11354961 0,13780511 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,11354961 0,13773669 GO:0051693|actin filament capping, ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,11354961 0,13766833 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,11354961 0,13760005 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,11354961 0,13753183 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,11354961 0,13746367 ! pallium development GO:0021543 56 24 0,000 0,11354961 0,13739559 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,11354961 0,13732757 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,11354961 0,13725962 ! platelet activation GO:0030168 41 24 0,000 0,11354961 0,13719174 ! aromatic amino acid family metabolic process GO:0009072 37 24 0,000 0,11354961 0,13712392 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,11354961 0,13705617 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,11354961 0,13698849 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,11354961 0,13692088 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,11354961 0,13685333 ! regulation of amine transport GO:0051952 41 24 0,000 0,11354961 0,13678585 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 0,000 0,11354961 0,13671843 ! positive regulation of fibroblast proliferation GO:0048146 48 25 0,000 0,11799184 0,14199708 ! myeloid leukocyte differentiation GO:0002573 46 25 0,000 0,11799184 0,14192717 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 0,000 0,11799184 0,14185732 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,11799184 0,14178754 ! leukocyte adhesion GO:0007159 55 25 0,000 0,11799184 0,14171783 ! phototransduction GO:0007602 37 25 0,000 0,11799184 0,14164819 ! keratinization GO:0031424 37 25 0,000 0,11799184 0,14157862 ! vacuole organization GO:0007033 49 25 0,000 0,11799184 0,14150912 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,11799184 0,14143968 ! negative regulation of DNA replication GO:0008156 45 25 0,000 0,11799184 0,14137032 ! receptor metabolic process GO:0043112 53 25 0,000 0,11799184 0,14130102 ! chromosome condensation GO:0030261 48 25 0,000 0,11799184 0,14123178 ! regulation of alpha-beta T cell activation GO:0046634 48 25 0,000 0,11799184 0,14116262 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,11799184 0,14109353 ! immunoglobulin production GO:0002377 62 25 0,000 0,11799184 0,1410245 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,11799184 0,14095554 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,11799184 0,14088664 ! liver development GO:0001889 55 25 0,000 0,11799184 0,14081782 ! initiation of viral infection GO:0019059 60 26 0,000 0,12241194 0,14602167 ! pyruvate metabolic process GO:0006090 43 26 0,000 0,12241194 0,1459504 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,12241194 0,14587921 ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,12241194 0,14580808 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,12241194 0,14573702 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,12241194 0,14566604 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,12241194 0,14559512 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,12241194 0,14552427 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,12241194 0,14545349 ! digestive system process GO:0022600 49 26 0,000 0,12241194 0,14538278 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,12241194 0,14531213 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,12241194 0,14524156 ! osteoblast differentiation GO:0001649 63 26 0,000 0,12241194 0,14517105 ! neural crest cell development GO:0014032 59 26 0,000 0,12241194 0,14510062 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 42 26 0,000 0,12241194 0,14503025 ! negative regulation of cell development GO:0010721 83 26 0,000 0,12241194 0,14495995 GO:0050768|negative regulation of neurogenesis, ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,12241194 0,14488972 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,12241194 0,14481955 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,12241194 0,14474945 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,12241194 0,14467943 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,12241194 0,14460946 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,12241194 0,14453957 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,12241194 0,14446974 ! blastocyst development GO:0001824 50 26 0,000 0,12241194 0,14439999 ! telomere organization GO:0032200 46 26 0,000 0,12241194 0,1443303 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,12241194 0,14426067 ! neural tube closure GO:0001843 58 26 0,000 0,12241194 0,14419111 GO:0060606|tube closure, ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,12241194 0,14412163 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,12241194 0,1440522 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,12681001 0,14915593 ! embryonic pattern specification GO:0009880 49 27 0,000 0,12681001 0,14908415 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,12681001 0,14901244 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,12681001 0,1489408 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,12681001 0,14886923 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,12681001 0,14879772 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,12681001 0,14872629 ! iron ion transport GO:0006826 65 27 0,000 0,12681001 0,14865492 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,12681001 0,14858363 ! superoxide metabolic process GO:0006801 41 27 0,000 0,12681001 0,1485124 ! tube lumen formation GO:0035148 59 27 0,000 0,12681001 0,14844124 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,12681001 0,14837014 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,12681001 0,14829912 ! response to starvation GO:0042594 47 27 0,000 0,12681001 0,14822816 ! cellular response to oxidative stress GO:0034599 43 27 0,000 0,12681001 0,14815727 ! cellular response to nutrient levels GO:0031669 45 27 0,000 0,12681001 0,14808645 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,12681001 0,1480157 ! regulation of fibroblast proliferation GO:0048145 56 28 0,000 0,13118616 0,15305053 ! neuron fate commitment GO:0048663 52 28 0,000 0,13118616 0,15297747 ! protein amino acid acylation GO:0043543 59 28 0,000 0,13118616 0,15290448 ! vesicle docking GO:0048278 55 28 0,000 0,13118616 0,15283157 ! circadian rhythm GO:0007623 56 28 0,000 0,13118616 0,15275872 ! dendrite development GO:0016358 67 28 0,000 0,13118616 0,15268595 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,13118616 0,15261324 ! sperm motility GO:0030317 37 28 0,000 0,13118616 0,1525406 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,13118616 0,15246803 ! base-excision repair GO:0006284 41 28 0,000 0,13118616 0,15239553 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,13118616 0,1523231 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,13118616 0,15225074 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,13118616 0,15217844 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,13118616 0,15210622 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,13118616 0,15203406 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,13118616 0,15196197 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,13118616 0,15188995 ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,13118616 0,151818 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,13118616 0,15174612 ! translational initiation GO:0006413 66 29 0,000 0,13554051 0,15670869 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,13554051 0,15663456 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! autophagy GO:0006914 47 29 0,000 0,13554051 0,1565605 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,13554051 0,15648651 ! primary neural tube formation GO:0014020 61 29 0,000 0,13554051 0,15641259 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,13554051 0,15633874 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 0,000 0,13554051 0,15626497 ! somitogenesis GO:0001756 52 29 0,000 0,13554051 0,15619126 ! negative regulation of neuron differentiation GO:0045665 46 29 0,000 0,13554051 0,15611761 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,13554051 0,15604404 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,13554051 0,15597054 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,13987315 0,16088046 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,13987315 0,16080476 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,13987315 0,16072912 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,13987315 0,16065355 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,13987315 0,16057806 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,13987315 0,16050263 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,13987315 0,16042728 ! acute-phase response GO:0006953 50 30 0,000 0,13987315 0,160352 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,13987315 0,16027679 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,13987315 0,16020164 ! myofibril assembly GO:0030239 50 30 0,000 0,13987315 0,16012657 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,13987315 0,16005157 ! determination of left/right symmetry GO:0007368 53 30 0,000 0,13987315 0,15997664 ! cell fate determination GO:0001709 64 30 0,000 0,13987315 0,15990178 ! phospholipid transport GO:0015914 65 30 0,000 0,13987315 0,15982699 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,13987315 0,15975227 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,13987315 0,15967762 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,13987315 0,15960304 ! regulation of coagulation GO:0050818 52 30 0,000 0,13987315 0,15952853 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,1441842 0,16436864 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,1441842 0,16429198 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,1441842 0,16421538 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,1441842 0,16413886 ! regulation of innate immune response GO:0045088 57 31 0,000 0,1441842 0,16406241 ! peptide transport GO:0015833 60 31 0,000 0,1441842 0,16398603 ! detection of light stimulus GO:0009583 44 31 0,000 0,1441842 0,16390972 ! cellular response to extracellular stimulus GO:0031668 52 31 0,000 0,1441842 0,16383349 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 0,000 0,1441842 0,16375732 ! natural killer cell activation GO:0030101 50 31 0,000 0,1441842 0,16368123 ! cofactor catabolic process GO:0051187 54 31 0,000 0,1441842 0,1636052 ! eye morphogenesis GO:0048592 65 31 0,000 0,1441842 0,16352925 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,1441842 0,16345336 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,14847376 0,16823812 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,14847376 0,16816013 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,14847376 0,1680822 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,14847376 0,16800435 ! regulation of protein import into nucleus GO:0042306 69 32 0,000 0,14847376 0,16792657 ! muscle cell development GO:0055001 52 32 0,000 0,14847376 0,16784887 ! mesoderm formation GO:0001707 73 32 0,000 0,14847376 0,16777123 ! hexose biosynthetic process GO:0019319 53 32 0,000 0,14847376 0,16769367 ! BMP signaling pathway GO:0030509 71 32 0,000 0,14847376 0,16761617 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,14847376 0,16753875 ! myeloid leukocyte activation GO:0002274 53 32 0,000 0,14847376 0,1674614 ! gene silencing GO:0016458 71 32 0,000 0,14847376 0,16738412 ! regulation of pH GO:0006885 56 33 0,000 0,15274194 0,1721165 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,15274194 0,17203714 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,15274194 0,17195786 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,15274194 0,17187866 ! positive regulation of gene-specific transcription GO:0043193 70 33 0,000 0,15274194 0,17179952 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,15274194 0,17172046 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,15274194 0,17164147 ! regulation of axonogenesis GO:0050770 86 33 0,000 0,15274194 0,17156256 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,15274194 0,17148372 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,15274194 0,17140495 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,15274194 0,17132625 ! negative regulation of protein transport GO:0051224 74 33 0,000 0,15274194 0,17124762 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,15274194 0,17116907 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,15698885 0,17584767 ! cholesterol transport GO:0030301 62 34 0,000 0,15698885 0,17576708 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,15698885 0,17568656 ! spliceosome assembly GO:0000245 75 34 0,000 0,15698885 0,17560612 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,15698885 0,17552575 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,15698885 0,17544545 ! formation of primary germ layer GO:0001704 76 34 0,000 0,15698885 0,17536523 ! cell fate specification GO:0001708 56 34 0,000 0,15698885 0,17528508 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,15698885 0,17520501 ! DNA damage checkpoint GO:0000077 78 35 0,000 0,16121459 0,17983892 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,16121459 0,17975684 ! negative regulation of secretion GO:0051048 68 35 0,000 0,16121459 0,17967484 ! negative regulation of DNA metabolic process GO:0051053 65 35 0,000 0,16121459 0,1795929 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,16121459 0,17951105 ! membrane docking GO:0022406 69 35 0,000 0,16121459 0,17942927 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,16121459 0,17934756 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,16121459 0,17926593 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,16121459 0,17918437 ! ceramide metabolic process GO:0006672 72 35 0,000 0,16121459 0,17910288 ! telencephalon development GO:0021537 81 35 0,000 0,16121459 0,17902147 ! sterol transport GO:0015918 63 35 0,000 0,16121459 0,17894014 ! calcium-mediated signaling GO:0019722 67 35 0,000 0,16121459 0,17885887 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,16121459 0,17877769 ! placenta development GO:0001890 53 35 0,000 0,16121459 0,17869657 ! vesicle localization GO:0051648 70 35 0,000 0,16121459 0,17861553 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,16541926 0,18319096 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,16541926 0,18310796 ! protein targeting to membrane GO:0006612 75 36 0,000 0,16541926 0,18302503 ! regulation of proteolysis GO:0030162 77 36 0,000 0,16541926 0,18294217 ! aerobic respiration GO:0009060 56 36 0,000 0,16541926 0,18285939 ! cytokine production GO:0001816 68 36 0,000 0,16541926 0,18277669 ! embryonic organ development GO:0048568 67 36 0,000 0,16541926 0,18269406 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,16541926 0,18261151 ! monosaccharide biosynthetic process GO:0046364 57 36 0,000 0,16541926 0,18252903 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,16960298 0,18706098 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! xenobiotic metabolic process GO:0006805 55 37 0,000 0,16960298 0,18697657 ! actomyosin structure organization GO:0031032 68 37 0,000 0,16960298 0,18689223 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,16960298 0,18680797 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,16960298 0,18672378 ! regulation of microtubule-based process GO:0032886 86 37 0,000 0,16960298 0,18663967 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 0,000 0,17376584 0,1911346 ! organic anion transport GO:0015711 82 38 0,000 0,17376584 0,19104858 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,17376584 0,19096264 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,17376584 0,19087677 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,17376584 0,19079099 GO:0006639|acylglycerol metabolic process, ! DNA integrity checkpoint GO:0031570 82 38 0,000 0,17376584 0,19070528 ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,17376584 0,19061964 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 0,000 0,17376584 0,19053409 ! spermatid development GO:0007286 69 38 0,000 0,17376584 0,19044861 ! neural tube formation GO:0001841 79 38 0,000 0,17376584 0,1903632 ! regulation of neuron projection development GO:0010975 102 39 0,000 0,17790795 0,19481359 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,17790795 0,19472631 ! mitotic cell cycle checkpoint GO:0007093 76 39 0,000 0,17790795 0,1946391 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,17790795 0,19455198 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,17790795 0,19446493 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,17790795 0,19437796 ! positive regulation of leukocyte proliferation GO:0070665 70 39 0,000 0,17790795 0,19429107 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 0,000 0,17790795 0,19420425 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,18202941 0,19861449 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,18202941 0,19852582 ! lipid homeostasis GO:0055088 75 40 0,000 0,18202941 0,19843723 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,18202941 0,19834872 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,18202941 0,19826029 ! RNA export from nucleus GO:0006405 61 41 0,000 0,18613032 0,20263653 ! mRNA catabolic process GO:0006402 79 41 0,000 0,18613032 0,20254627 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,18613032 0,20245608 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,18613032 0,20236598 ! monovalent inorganic cation homeostasis GO:0055067 72 41 0,000 0,18613032 0,20227596 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,18613032 0,20218602 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,18613032 0,20209616 ! spermatid differentiation GO:0048515 73 41 0,000 0,18613032 0,20200638 ! embryonic epithelial tube formation GO:0001838 85 41 0,000 0,18613032 0,20191668 ! RNA modification GO:0009451 64 41 0,000 0,18613032 0,20182706 ! organic ether metabolic process GO:0018904 59 42 0,000 0,19021078 0,20616014 ! alcohol biosynthetic process GO:0046165 65 42 0,000 0,19021078 0,20606871 ! regulation of intracellular protein transport GO:0033157 86 42 0,000 0,19021078 0,20597737 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,19021078 0,20588611 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,19021078 0,20579493 ! regulation of protein secretion GO:0050708 77 42 0,000 0,19021078 0,20570383 ! dorsal/ventral pattern formation GO:0009953 75 42 0,000 0,19021078 0,20561281 ! response to xenobiotic stimulus GO:0009410 63 42 0,000 0,19021078 0,20552187 ! positive regulation of transcription factor activity GO:0051091 71 43 0,000 0,19427091 0,20981601 GO:0090047|positive regulation of transcription regulator activity, ! epithelial cell differentiation GO:0030855 83 43 0,000 0,19427091 0,2097233 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,19427091 0,20963066 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,19427091 0,20953811 ! regulation of tube size GO:0035150 76 43 0,000 0,19427091 0,20944564 GO:0050880|regulation of blood vessel size, ! glucose transport GO:0015758 66 43 0,000 0,19427091 0,20935325 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,19427091 0,20926095 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,19427091 0,20916872 ! segmentation GO:0035282 78 43 0,000 0,19427091 0,20907657 ! ion transmembrane transport GO:0034220 79 43 0,000 0,19427091 0,20898451 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,19831079 0,21323647 ! negative regulation of protein complex disassembly GO:0043242 113 44 0,000 0,19831079 0,21314265 ! hexose transport GO:0008645 68 44 0,000 0,19831079 0,21304892 GO:0015749|monosaccharide transport, ! striated muscle contraction GO:0006941 85 44 0,000 0,19831079 0,21295528 ! phagocytosis GO:0006909 105 44 0,000 0,19831079 0,21286171 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,19831079 0,21276823 ! double-strand break repair GO:0006302 85 44 0,000 0,19831079 0,21267483 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,20233052 0,21689051 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,20233052 0,21679538 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,20233052 0,21670034 ! biopolymer methylation GO:0043414 91 45 0,000 0,20233052 0,21660538 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,20233052 0,2165105 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,20233052 0,21641571 ! maintenance of location in cell GO:0051651 101 45 0,000 0,20233052 0,21632099 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,20633022 0,22050075 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,20633022 0,22040434 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 0,000 0,20633022 0,22030801 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,20633022 0,22021176 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 0,000 0,20633022 0,2201156 ! cell growth GO:0016049 90 46 0,000 0,20633022 0,22001952 ! positive regulation of protein transport GO:0051222 80 46 0,000 0,20633022 0,21992353 ! neural tube development GO:0021915 91 47 0,000 0,21030997 0,22406771 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,21030997 0,22397003 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,21426988 0,22808772 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,21426988 0,22798838 ! positive regulation of DNA binding GO:0043388 83 48 0,000 0,21426988 0,22788912 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,21426988 0,22778995 ! methylation GO:0032259 97 48 0,000 0,21426988 0,22769087 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,21821004 0,23177701 ! regulation of ion transport GO:0043269 86 50 0,000 0,22213055 0,23583874 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,22213055 0,23573629 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,22213055 0,23563393 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,22213055 0,23553166 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,22213055 0,23542947 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,22213055 0,23532738 ! positive regulation of cytokine production GO:0001819 94 50 0,000 0,22213055 0,23522537 ! regulation of cell projection organization GO:0031344 135 51 0,000 0,22603151 0,2392526 ! viral infectious cycle GO:0019058 104 51 0,000 0,22603151 0,23914898 ! positive regulation of binding GO:0051099 88 52 0,000 0,22991302 0,24315044 ! Notch signaling pathway GO:0007219 111 52 0,000 0,22991302 0,24304523 ! regulation of protein complex disassembly GO:0043244 127 52 0,000 0,22991302 0,2429401 ! morphogenesis of embryonic epithelium GO:0016331 106 52 0,000 0,22991302 0,24283507 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,22991302 0,24273013 ! excretion GO:0007588 87 52 0,000 0,22991302 0,24262528 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,22991302 0,24252052 ! histone modification GO:0016570 104 52 0,000 0,22991302 0,24241585 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,22991302 0,24231127 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,22991302 0,24220678 ! amino acid activation GO:0043038 98 52 0,000 0,22991302 0,24210238 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,23377517 0,24606323 ! inner ear development GO:0048839 89 53 0,000 0,23377517 0,24595726 ! chromatin remodeling GO:0006338 122 53 0,000 0,23377517 0,24585138 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,23377517 0,24574559 ! regulation of translational initiation GO:0006446 87 54 0,000 0,23761806 0,24967782 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,23761806 0,24957048 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,23761806 0,24946323 ! covalent chromatin modification GO:0016569 115 54 0,000 0,23761806 0,24935607 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,23761806 0,24924901 ! RNA catabolic process GO:0006401 103 55 0,000 0,24144179 0,2531512 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,24144179 0,2530426 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,24144179 0,25293409 ! cell recognition GO:0008037 98 55 0,000 0,24144179 0,25282567 ! cell maturation GO:0048469 107 55 0,000 0,24144179 0,25271735 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,24144179 0,25260912 ! negative regulation of cytoskeleton organization GO:0051494 139 56 0,000 0,24524644 0,25647991 ! RNA elongation GO:0006354 90 56 0,000 0,24524644 0,25637016 ! chloride transport GO:0006821 102 57 0,000 0,24903212 0,2602162 ! nucleotide-excision repair GO:0006289 91 57 0,000 0,24903212 0,26010495 ! regulation of intracellular transport GO:0032386 108 57 0,000 0,24903212 0,25999379 ! regulation of actin filament length GO:0030832 118 58 0,000 0,25279892 0,26381365 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,25279892 0,26370101 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,25279892 0,26358846 ! gastrulation GO:0007369 122 58 0,000 0,25279892 0,263476 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,25279892 0,26336365 ! maintenance of location GO:0051235 124 58 0,000 0,25279892 0,26325139 ! nuclear export GO:0051168 110 59 0,000 0,25654692 0,26704054 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,26027624 0,270807 ! regulation of endocytosis GO:0030100 104 60 0,000 0,26027624 0,27069172 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,26027624 0,27057653 ! regulation of cellular component size GO:0032535 125 61 0,000 0,26398695 0,27431736 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,26398695 0,27420073 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,26398695 0,27408419 ! camera-type eye development GO:0043010 126 61 0,000 0,26398695 0,27396776 ! proton transport GO:0015992 117 61 0,000 0,26398695 0,27385143 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,26767915 0,27756373 ! tRNA processing GO:0008033 102 62 0,000 0,26767915 0,27744597 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,27135293 0,28113452 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,27135293 0,28101535 ! hydrogen transport GO:0006818 121 64 0,000 0,27500838 0,28468029 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,27500838 0,28455971 ! integrin-mediated signaling pathway GO:0007229 160 64 0,000 0,27500838 0,28443924 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,2786456 0,28807922 ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,2786456 0,28795736 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,2786456 0,2878356 ! regulation of cytokine biosynthetic process GO:0042035 108 66 0,000 0,28226467 0,2914508 ! embryonic limb morphogenesis GO:0030326 139 67 0,000 0,28586569 0,29504431 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,28586569 0,29491971 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,28586569 0,29479522 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,28944874 0,29836425 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,28944874 0,29823841 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,28944874 0,29811268 ! cell projection assembly GO:0030031 138 68 0,000 0,28944874 0,29798705 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,29301392 0,30153033 ! cellular amino acid catabolic process GO:0009063 120 69 0,000 0,29301392 0,30140337 ! developmental maturation GO:0021700 128 69 0,000 0,29301392 0,30127651 ! single fertilization GO:0007338 83 69 0,000 0,29301392 0,30114977 ! cell redox homeostasis GO:0045454 114 70 0,000 0,2965613 0,30466748 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,2965613 0,30453941 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,30009099 0,30803457 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,30009099 0,3079052 ! appendage morphogenesis GO:0035107 150 72 0,000 0,30360306 0,31137795 GO:0035108|limb morphogenesis, ! carbohydrate transport GO:0008643 114 72 0,000 0,30360306 0,31124729 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,30360306 0,31111673 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,30360306 0,31098628 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,30360306 0,31085594 ! appendage development GO:0048736 151 73 0,000 0,30709761 0,31430225 GO:0060173|limb development, ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,30709761 0,31417063 ! regulation of immune effector process GO:0002697 156 73 0,000 0,30709761 0,31403912 ! acute inflammatory response GO:0002526 118 74 0,000 0,31057472 0,31746195 ! transition metal ion transport GO:0000041 143 75 0,000 0,31403448 0,32086418 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,31403448 0,32073004 ! eye development GO:0001654 155 75 0,000 0,31403448 0,32059601 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,31747698 0,32397505 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,31747698 0,32383977 ! regulation of blood pressure GO:0008217 134 76 0,000 0,31747698 0,32370462 ! amine catabolic process GO:0009310 136 77 0,000 0,32090229 0,32706062 ! neurotransmitter transport GO:0006836 142 77 0,000 0,32090229 0,32692423 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,32090229 0,32678796 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,32090229 0,32665179 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,32090229 0,32651575 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,32431052 0,32984621 ! antigen processing and presentation GO:0019882 117 78 0,000 0,32431052 0,32970894 ! fertilization GO:0009566 99 78 0,000 0,32431052 0,32957179 ! positive regulation of lymphocyte activation GO:0051251 142 78 0,000 0,32431052 0,32943476 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,32770173 0,3327412 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,32770173 0,33260296 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,33443346 0,33929441 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,34109816 0,34591234 ! exocytosis GO:0006887 153 83 0,000 0,34109816 0,3457688 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,34109816 0,34562539 ! inorganic anion transport GO:0015698 156 83 0,000 0,34109816 0,3454821 ! digestion GO:0007586 130 84 0,000 0,34440559 0,34868746 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,3476965 0,35187347 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,3476965 0,35172777 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,35097099 0,35489326 ! regulation of lyase activity GO:0051339 169 86 0,000 0,35097099 0,35474643 ! positive regulation of cell activation GO:0050867 161 86 0,000 0,35097099 0,35459972 GO:0002696|positive regulation of leukocyte activation, ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,35422913 0,3577436 ! nucleosome assembly GO:0006334 126 87 0,000 0,35422913 0,35759577 ! regulation of protein transport GO:0051223 165 87 0,000 0,35422913 0,35744806 GO:0070201|regulation of establishment of protein localization, ! cellular respiration GO:0045333 143 88 0,000 0,35747101 0,36057047 ! amine biosynthetic process GO:0009309 146 88 0,000 0,35747101 0,36042165 ! sensory perception of smell GO:0007608 117 88 0,000 0,35747101 0,36027296 ! chromatin assembly GO:0031497 128 88 0,000 0,35747101 0,3601244 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,35747101 0,35997596 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,3606967 0,36307459 ! cellular defense response GO:0006968 123 89 0,000 0,3606967 0,36292506 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,36390629 0,36600373 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,36709985 0,36906376 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,36709985 0,36891195 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,37027748 0,37195225 ! vitamin metabolic process GO:0006766 153 93 0,000 0,37343923 0,37497412 ! nitrogen compound catabolic process GO:0044270 167 94 0,000 0,3765852 0,37797767 ! sterol metabolic process GO:0016125 166 94 0,000 0,3765852 0,37782244 ! carbohydrate biosynthetic process GO:0016051 158 94 0,000 0,3765852 0,37766734 ! nucleosome organization GO:0034728 143 95 0,000 0,37971547 0,38065034 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,37971547 0,38049421 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,37971547 0,38033821 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,37971547 0,38018233 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,37971547 0,38002658 ! mRNA transport GO:0051028 185 100 0,000 0,39513388 0,39529569 ! hormone metabolic process GO:0042445 171 100 0,000 0,39513388 0,39513388