pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6427-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 52 51 6,000 1,601E-07 2,951E-04 GO:0051325|interphase, ! androgen receptor signaling pathway GO:0030521 24 24 4,000 1,23E-06 1,134E-03 ! G1 phase GO:0051318 13 12 3,000 1,995E-06 1,226E-03 ! regulation of DNA metabolic process GO:0051052 51 50 5,000 2,963E-06 1,365E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 3,000 3,985E-06 1,469E-03 ! regulation of DNA replication GO:0006275 32 31 4,000 4,706E-06 1,446E-03 ! T cell lineage commitment GO:0002360 5 5 2,000 5,33E-06 1,403E-03 ! response to peptide hormone stimulus GO:0043434 36 34 4,000 7,562E-06 1,742E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 4,000 8,767E-06 1,795E-03 ! focal adhesion formation GO:0048041 7 6 2,000 1,06E-05 1,953E-03 ! meiosis GO:0007126 37 37 4,000 1,162E-05 1,948E-03 GO:0051327|M phase of meiotic cell cycle, ! meiosis I GO:0007127 18 18 3,000 1,188E-05 1,825E-03 ! meiotic cell cycle GO:0051321 38 38 4,000 1,33E-05 1,886E-03 ! steroid hormone receptor signaling pathway GO:0030518 38 38 4,000 1,33E-05 1,751E-03 ! posttranscriptional regulation of gene expression GO:0010608 98 98 6,000 1,416E-05 1,74E-03 ! regulation of protein stability GO:0031647 19 19 3,000 1,496E-05 1,723E-03 ! nucleotide-excision repair GO:0006289 40 39 4,000 1,516E-05 1,644E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 4,000 1,722E-05 1,763E-03 ! response to gamma radiation GO:0010332 8 7 2,000 1,844E-05 1,788E-03 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 3,000 2,282E-05 2,103E-03 ! regulation of cell migration GO:0030334 71 71 5,000 2,336E-05 2,05E-03 ! release of cytochrome c from mitochondria GO:0001836 9 8 2,000 2,932E-05 2,457E-03 ! regulation of locomotion GO:0040012 79 79 5,000 4,309E-05 3,452E-03 ! regulation of cell motion GO:0051270 79 79 5,000 4,309E-05 3,309E-03 ! cell cycle arrest GO:0007050 49 49 4,000 4,715E-05 3,476E-03 ! negative regulation of cell migration GO:0030336 26 26 3,000 5,527E-05 3,918E-03 ! response to insulin stimulus GO:0032868 28 26 3,000 5,527E-05 3,773E-03 ! reciprocal meiotic recombination GO:0007131 10 10 2,000 6,21E-05 4,087E-03 ! apoptotic mitochondrial changes GO:0008637 11 10 2,000 6,21E-05 3,947E-03 ! cell-substrate junction assembly GO:0007044 11 10 2,000 6,21E-05 3,815E-03 ! regulation of protein binding GO:0043393 11 10 2,000 6,21E-05 3,692E-03 ! protein stabilization GO:0050821 10 10 2,000 6,21E-05 3,577E-03 ! G1 phase of mitotic cell cycle GO:0000080 12 11 2,000 8,489E-05 4,741E-03 ! regulation of epithelial cell proliferation GO:0050678 29 29 3,000 8,62E-05 4,672E-03 ! response to UV GO:0009411 29 29 3,000 8,62E-05 4,539E-03 ! DNA replication GO:0006260 91 91 5,000 9,571E-05 4,9E-03 ! regulation of binding GO:0051098 60 57 4,000 9,843E-05 4,903E-03 ! negative regulation of cell motion GO:0051271 31 31 3,000 1,128E-04 5,47E-03 ! negative regulation of cell growth GO:0030308 32 32 3,000 1,281E-04 6,054E-03 ! negative regulation of cell size GO:0045792 33 33 3,000 1,449E-04 6,676E-03 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 2,000 1,454E-04 6,536E-03 ! mitochondrial membrane organization GO:0007006 13 13 2,000 1,454E-04 6,381E-03 ! negative regulation of DNA replication GO:0008156 13 13 2,000 1,454E-04 6,232E-03 ! receptor metabolic process GO:0043112 14 13 2,000 1,454E-04 6,091E-03 ! cell aging GO:0007569 13 13 2,000 1,454E-04 5,955E-03 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 2,000 1,454E-04 5,826E-03 ! tissue homeostasis GO:0001894 13 13 2,000 1,454E-04 5,702E-03 GO:0048871|multicellular organismal homeostasis, ! response to hormone stimulus GO:0009725 102 100 5,000 1,616E-04 6,206E-03 ! base-excision repair GO:0006284 14 14 2,000 1,84E-04 6,92E-03 ! positive regulation of cell migration GO:0030335 36 36 3,000 2,048E-04 7,547E-03 ! integrin-mediated signaling pathway GO:0007229 36 36 3,000 2,048E-04 7,399E-03 ! response to drug GO:0042493 37 37 3,000 2,282E-04 8,087E-03 ! negative regulation of growth GO:0045926 37 37 3,000 2,282E-04 7,934E-03 ! response to ionizing radiation GO:0010212 16 15 2,000 2,286E-04 7,803E-03 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 2,000 2,286E-04 7,661E-03 ! response to nutrient levels GO:0031667 69 69 4,000 2,45E-04 8,062E-03 ! regulation of mitotic cell cycle GO:0007346 72 69 4,000 2,45E-04 7,92E-03 ! cell-matrix adhesion GO:0007160 39 38 3,000 2,534E-04 8,053E-03 ! positive regulation of cell motion GO:0051272 39 39 3,000 2,807E-04 8,767E-03 ! response to extracellular stimulus GO:0009991 72 72 4,000 2,993E-04 9,192E-03 ! cell junction assembly GO:0034329 18 17 2,000 3,377E-04 0,01020251 ! cell cycle checkpoint GO:0000075 42 41 3,000 3,413E-04 0,01014664 ! cell-substrate adhesion GO:0031589 43 42 3,000 3,75E-04 0,010969 ! B cell differentiation GO:0030183 18 18 2,000 4,028E-04 0,01160067 ! DNA damage checkpoint GO:0000077 19 19 2,000 4,756E-04 0,01348433 ! negative regulation of DNA metabolic process GO:0051053 19 19 2,000 4,756E-04 0,01328002 ! negative regulation of binding GO:0051100 21 20 2,000 5,562E-04 0,01530014 ! actin filament organization GO:0007015 50 48 3,000 6,282E-04 0,01702664 ! DNA integrity checkpoint GO:0031570 21 21 2,000 6,451E-04 0,01723118 ! cellular response to insulin stimulus GO:0032869 23 21 2,000 6,451E-04 0,01698502 ! negative regulation of protein transport GO:0051224 21 21 2,000 6,451E-04 0,0167458 ! regulation of multicellular organism growth GO:0040014 21 21 2,000 6,451E-04 0,01651322 ! positive regulation of cell differentiation GO:0045597 87 85 4,000 6,465E-04 0,01632172 ! prostate gland development GO:0030850 5 5 1,000 6,637E-04 0,01653036 ! metencephalon development GO:0022037 5 5 1,000 6,637E-04 0,01630996 ! dopamine receptor signaling pathway GO:0007212 5 5 1,000 6,637E-04 0,01609535 ! response to lipid GO:0033993 5 5 1,000 6,637E-04 0,01588632 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 1,000 6,637E-04 0,01568265 ! regulation of appetite GO:0032098 5 5 1,000 6,637E-04 0,01548414 GO:0032095|regulation of response to food, ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 6,637E-04 0,01529059 ! receptor clustering GO:0043113 5 5 1,000 6,637E-04 0,01510181 ! fear response GO:0042596 5 5 1,000 6,637E-04 0,01491765 ! actin cytoskeleton reorganization GO:0031532 5 5 1,000 6,637E-04 0,01473791 ! response to UV-B GO:0010224 5 5 1,000 6,637E-04 0,01456246 ! enucleate erythrocyte differentiation GO:0043353 6 5 1,000 6,637E-04 0,01439114 ! regulation of mitochondrial membrane potential GO:0051881 5 5 1,000 6,637E-04 0,0142238 ! cellular pigmentation GO:0033059 5 5 1,000 6,637E-04 0,01406031 ! DNA methylation GO:0006306 5 5 1,000 6,637E-04 0,01390053 GO:0006305|DNA alkylation, ! peptidyl-lysine modification GO:0018205 5 5 1,000 6,637E-04 0,01374435 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 6,637E-04 0,01359163 ! oocyte differentiation GO:0009994 5 5 1,000 6,637E-04 0,01344227 GO:0048599|oocyte development, ! regulation of protein homodimerization activity GO:0043496 6 5 1,000 6,637E-04 0,01329616 ! spleen development GO:0048536 5 5 1,000 6,637E-04 0,01315319 ! response to nicotine GO:0035094 5 5 1,000 6,637E-04 0,01301327 ! leukocyte differentiation GO:0002521 50 49 3,000 6,799E-04 0,01318952 ! gland development GO:0048732 51 49 3,000 6,799E-04 0,01305213 ! cell junction organization GO:0034330 23 22 2,000 7,426E-04 0,01410943 ! epithelial cell differentiation GO:0030855 23 23 2,000 8,49E-04 0,01596621 ! cell fate commitment GO:0045165 52 52 3,000 8,528E-04 0,0158767 ! response to light stimulus GO:0009416 53 52 3,000 8,528E-04 0,01571793 ! negative regulation of cell cycle GO:0045786 92 91 4,000 8,826E-04 0,01610599 ! mitochondrial transport GO:0006839 24 24 2,000 9,646E-04 0,01742887 ! glucose homeostasis GO:0042593 24 24 2,000 9,646E-04 0,01725965 GO:0033500|carbohydrate homeostasis, ! T cell differentiation GO:0030217 24 24 2,000 9,646E-04 0,01709369 ! protein amino acid dephosphorylation GO:0006470 55 54 3,000 9,841E-04 0,01727333 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 9,903E-04 0,01721797 GO:0018409|peptide or protein amino-terminal blocking, ! regulation of lipid kinase activity GO:0043550 6 6 1,000 9,903E-04 0,01705706 ! bile acid metabolic process GO:0008206 6 6 1,000 9,903E-04 0,01689912 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 9,903E-04 0,01674408 ! ER overload response GO:0006983 6 6 1,000 9,903E-04 0,01659187 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 9,903E-04 0,01644239 GO:0070667|negative regulation of mast cell proliferation, ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 9,903E-04 0,01629558 ! negative regulation of ossification GO:0030279 6 6 1,000 9,903E-04 0,01615137 ! G1 DNA damage checkpoint GO:0031571 6 6 1,000 9,903E-04 0,01600969 ! DNA unwinding during replication GO:0006268 6 6 1,000 9,903E-04 0,01587048 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 9,903E-04 0,01573367 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 9,903E-04 0,01559919 ! regulation of lipid transport GO:0032368 6 6 1,000 9,903E-04 0,01546699 ! thymus development GO:0048538 6 6 1,000 9,903E-04 0,01533702 ! localization within membrane GO:0051668 6 6 1,000 9,903E-04 0,01520921 ! microtubule cytoskeleton organization GO:0000226 55 55 3,000 1,055E-03 0,01606595 ! regulation of cell adhesion GO:0030155 56 55 3,000 1,055E-03 0,01593426 ! regulation of intracellular protein transport GO:0033157 25 25 2,000 1,09E-03 0,01632795 ! regulation of cell growth GO:0001558 97 96 4,000 1,124E-03 0,01670941 ! regulation of protein localization GO:0032880 58 57 3,000 1,207E-03 0,01779239 ! double-strand break repair GO:0006302 27 26 2,000 1,225E-03 0,01791277 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 4,000 1,35E-03 0,01959652 ! hemopoiesis GO:0030097 104 100 4,000 1,35E-03 0,01944342 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 2,000 1,37E-03 0,01956807 ! dephosphorylation GO:0016311 60 59 3,000 1,373E-03 0,01947131 ! double-strand break repair via homologous recombination GO:0000724 7 7 1,000 1,379E-03 0,01940119 GO:0000725|recombinational repair, ! hair follicle morphogenesis GO:0031069 7 7 1,000 1,379E-03 0,01925422 ! digestive system development GO:0055123 7 7 1,000 1,379E-03 0,01910945 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! regulation of mRNA processing GO:0050684 7 7 1,000 1,379E-03 0,01896684 ! regulation of skeletal muscle fiber development GO:0048742 7 7 1,000 1,379E-03 0,01882634 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 1,379E-03 0,01868791 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! response to X-ray GO:0010165 7 7 1,000 1,379E-03 0,01855151 ! regulation of intracellular pH GO:0051453 7 7 1,000 1,379E-03 0,01841708 ! alpha-beta T cell differentiation GO:0046632 7 7 1,000 1,379E-03 0,01828458 ! axon cargo transport GO:0008088 7 7 1,000 1,379E-03 0,01815397 ! eating behavior GO:0042755 7 7 1,000 1,379E-03 0,01802522 ! regulation of macrophage differentiation GO:0045649 8 7 1,000 1,379E-03 0,01789828 ! adult feeding behavior GO:0008343 7 7 1,000 1,379E-03 0,01777312 ! negative regulation of T cell activation GO:0050868 7 7 1,000 1,379E-03 0,0176497 ! protein amino acid autophosphorylation GO:0046777 28 28 2,000 1,525E-03 0,01938386 ! morphogenesis of an epithelium GO:0002009 63 62 3,000 1,653E-03 0,02086301 GO:0060429|epithelium development, ! positive regulation of cell cycle GO:0045787 29 29 2,000 1,691E-03 0,02120161 ! branching morphogenesis of a tube GO:0048754 29 29 2,000 1,691E-03 0,02105835 ! DNA-dependent DNA replication GO:0006261 29 29 2,000 1,691E-03 0,02091702 ! regulation of skeletal muscle tissue development GO:0048641 8 8 1,000 1,829E-03 0,02247152 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 1,829E-03 0,0223227 ! regulation of response to extracellular stimulus GO:0032104 8 8 1,000 1,829E-03 0,02217584 GO:0032107|regulation of response to nutrient levels, ! T cell selection GO:0045058 8 8 1,000 1,829E-03 0,0220309 ! DNA duplex unwinding GO:0032508 8 8 1,000 1,829E-03 0,02188784 GO:0032392|DNA geometric change, ! negative regulation of mitotic cell cycle GO:0045930 9 8 1,000 1,829E-03 0,02174663 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 1,000 1,829E-03 0,02160723 ! alpha-beta T cell activation GO:0046631 8 8 1,000 1,829E-03 0,0214696 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 1,000 1,829E-03 0,02133372 ! T cell homeostasis GO:0043029 8 8 1,000 1,829E-03 0,02119954 ! peptidyl-serine modification GO:0018209 8 8 1,000 1,829E-03 0,02106705 ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 1,829E-03 0,02093619 ! regulation of steroid biosynthetic process GO:0050810 8 8 1,000 1,829E-03 0,02080696 ! response to reactive oxygen species GO:0000302 31 30 2,000 1,868E-03 0,02112079 ! regulation of intracellular transport GO:0032386 31 31 2,000 2,056E-03 0,02310534 ! B cell activation GO:0042113 31 31 2,000 2,056E-03 0,02296531 ! aging GO:0007568 32 31 2,000 2,056E-03 0,02282696 ! regulation of myeloid cell differentiation GO:0045637 32 31 2,000 2,056E-03 0,02269027 ! negative regulation of protein metabolic process GO:0051248 66 66 3,000 2,084E-03 0,02285734 ! striated muscle tissue development GO:0014706 69 67 3,000 2,202E-03 0,02401716 ! cell maturation GO:0048469 32 32 2,000 2,255E-03 0,02445202 ! morphogenesis of a branching structure GO:0001763 32 32 2,000 2,255E-03 0,02430903 ! response to radiation GO:0009314 70 68 3,000 2,326E-03 0,02492002 ! regulation of cell size GO:0008361 68 68 3,000 2,326E-03 0,02477598 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 2,339E-03 0,02477452 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 2,339E-03 0,02463295 ! regulation of cell-cell adhesion GO:0022407 9 9 1,000 2,339E-03 0,02449299 ! RNA polyadenylation GO:0043631 9 9 1,000 2,339E-03 0,02435462 GO:0006378|mRNA polyadenylation, ! response to alkaloid GO:0043279 10 9 1,000 2,339E-03 0,02421779 ! response to ethanol GO:0045471 9 9 1,000 2,339E-03 0,0240825 ! activation of pro-apoptotic gene products GO:0008633 9 9 1,000 2,339E-03 0,02394871 ! central nervous system neuron development GO:0021954 10 9 1,000 2,339E-03 0,02381639 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 1,000 2,339E-03 0,02368553 GO:0060675|ureteric bud morphogenesis, ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 2,339E-03 0,0235561 ! T cell differentiation in the thymus GO:0033077 9 9 1,000 2,339E-03 0,02342808 ! regulation of cellular pH GO:0030641 9 9 1,000 2,339E-03 0,02330144 ! histone acetylation GO:0016573 9 9 1,000 2,339E-03 0,02317617 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 2,339E-03 0,02305223 ! defense response to virus GO:0051607 9 9 1,000 2,339E-03 0,02292961 ! regulation of translation GO:0006417 69 69 3,000 2,454E-03 0,02392714 ! regulation of neuron apoptosis GO:0043523 34 33 2,000 2,467E-03 0,0239254 ! muscle tissue development GO:0060537 72 70 3,000 2,587E-03 0,02495824 ! regulation of protein catabolic process GO:0042176 35 34 2,000 2,689E-03 0,02581582 ! regulation of lipid metabolic process GO:0019216 34 34 2,000 2,689E-03 0,02568206 ! regulation of protein ubiquitination GO:0031396 10 10 1,000 2,908E-03 0,02762807 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 1,000 2,908E-03 0,02748639 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 2,908E-03 0,02734615 ! regulation of lipid biosynthetic process GO:0046890 10 10 1,000 2,908E-03 0,02720734 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 2,908E-03 0,02706993 ! fat cell differentiation GO:0045444 10 10 1,000 2,908E-03 0,0269339 ! centrosome cycle GO:0007098 10 10 1,000 2,908E-03 0,02679923 ! epidermis morphogenesis GO:0048730 10 10 1,000 2,908E-03 0,0266659 ! central nervous system neuron differentiation GO:0021953 11 10 1,000 2,908E-03 0,02653389 ! neuromuscular junction development GO:0007528 10 10 1,000 2,908E-03 0,02640318 ! intermediate filament cytoskeleton organization GO:0045104 10 10 1,000 2,908E-03 0,02627376 ! gland morphogenesis GO:0022612 10 10 1,000 2,908E-03 0,02614559 ! lymphocyte homeostasis GO:0002260 10 10 1,000 2,908E-03 0,02601867 ! gut development GO:0048565 10 10 1,000 2,908E-03 0,02589298 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 2,908E-03 0,02576849 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 2,908E-03 0,0256452 ! mRNA 3'-end processing GO:0031124 10 10 1,000 2,908E-03 0,02552308 ! regulation of transcription factor activity GO:0051090 38 37 2,000 3,431E-03 0,02997161 GO:0090046|regulation of transcription regulator activity, ! negative regulation of protein kinase activity GO:0006469 37 37 2,000 3,431E-03 0,02983024 ! lung development GO:0030324 38 37 2,000 3,431E-03 0,02969019 ! DNA damage response, signal transduction GO:0042770 37 37 2,000 3,431E-03 0,02955145 ! myeloid leukocyte differentiation GO:0002573 12 11 1,000 3,536E-03 0,03030771 ! signal complex assembly GO:0007172 11 11 1,000 3,536E-03 0,0301674 ! microtubule-based transport GO:0010970 11 11 1,000 3,536E-03 0,03002838 ! endothelial cell migration GO:0043542 11 11 1,000 3,536E-03 0,02989063 ! protein amino acid acetylation GO:0006473 11 11 1,000 3,536E-03 0,02975415 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 1,000 3,536E-03 0,0296189 GO:0032388|positive regulation of intracellular transport, ! regulation of viral genome replication GO:0045069 11 11 1,000 3,536E-03 0,02948488 ! activation of MAPKK activity GO:0000186 12 11 1,000 3,536E-03 0,02935206 ! cellular response to starvation GO:0009267 11 11 1,000 3,536E-03 0,02922044 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 3,536E-03 0,02908999 ! regulation of cellular ketone metabolic process GO:0010565 11 11 1,000 3,536E-03 0,0289607 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 1,000 3,536E-03 0,02883256 ! G1/S transition checkpoint GO:0031575 12 11 1,000 3,536E-03 0,02870554 ! intermediate filament-based process GO:0045103 11 11 1,000 3,536E-03 0,02857964 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 3,536E-03 0,02845484 ! oogenesis GO:0048477 11 11 1,000 3,536E-03 0,02833112 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 3,536E-03 0,02820848 GO:0006109|regulation of carbohydrate metabolic process, ! hindbrain development GO:0030902 11 11 1,000 3,536E-03 0,02808689 ! RNA 3'-end processing GO:0031123 11 11 1,000 3,536E-03 0,02796634 ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 3,536E-03 0,02784683 ! negative regulation of kinase activity GO:0033673 38 38 2,000 3,704E-03 0,02904695 ! urogenital system development GO:0001655 38 38 2,000 3,704E-03 0,02892387 ! respiratory tube development GO:0030323 40 39 2,000 3,989E-03 0,0310201 ! respiratory system development GO:0060541 40 39 2,000 3,989E-03 0,03088976 ! developmental maturation GO:0021700 39 39 2,000 3,989E-03 0,03076051 ! lymphocyte differentiation GO:0030098 39 39 2,000 3,989E-03 0,03063235 ! protein oligomerization GO:0051259 39 39 2,000 3,989E-03 0,03050524 ! neuron projection development GO:0031175 85 80 3,000 4,197E-03 0,031962 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 4,22E-03 0,03200789 ! microtubule organizing center organization GO:0031023 12 12 1,000 4,22E-03 0,03187671 GO:0051297|centrosome organization, ! male gonad development GO:0008584 12 12 1,000 4,22E-03 0,0317466 ! regulation of insulin secretion GO:0050796 12 12 1,000 4,22E-03 0,03161755 ! renal system process GO:0003014 12 12 1,000 4,22E-03 0,03148954 ! regulation of steroid metabolic process GO:0019218 12 12 1,000 4,22E-03 0,03136257 ! regulation of chromosome organization GO:0033044 12 12 1,000 4,22E-03 0,03123661 ! positive regulation of multicellular organism growth GO:0040018 12 12 1,000 4,22E-03 0,03111167 ! somitogenesis GO:0001756 13 12 1,000 4,22E-03 0,03098771 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 4,22E-03 0,03086475 ! negative regulation of translation GO:0017148 12 12 1,000 4,22E-03 0,03074275 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 1,000 4,22E-03 0,03062172 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 1,000 4,22E-03 0,03050163 ! negative regulation of transferase activity GO:0051348 40 40 2,000 4,287E-03 0,03086538 ! myeloid cell differentiation GO:0030099 42 40 2,000 4,287E-03 0,03074528 ! tube development GO:0035295 83 81 3,000 4,388E-03 0,03134509 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 2,000 4,924E-03 0,03503666 ! regeneration GO:0031099 13 13 1,000 4,961E-03 0,03516676 ! post-embryonic development GO:0009791 14 13 1,000 4,961E-03 0,03503202 ! negative regulation of protein modification process GO:0031400 13 13 1,000 4,961E-03 0,03489831 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 4,961E-03 0,03476562 ! response to corticosteroid stimulus GO:0031960 13 13 1,000 4,961E-03 0,03463393 GO:0051384|response to glucocorticoid stimulus, ! actin filament bundle formation GO:0051017 13 13 1,000 4,961E-03 0,03450324 ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 4,961E-03 0,03437352 ! ureteric bud development GO:0001657 13 13 1,000 4,961E-03 0,03424478 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 1,000 4,961E-03 0,034117 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 4,961E-03 0,03399018 ! regulation of peptide secretion GO:0002791 13 13 1,000 4,961E-03 0,03386429 ! regulation of viral reproduction GO:0050792 13 13 1,000 4,961E-03 0,03373933 ! long-chain fatty acid transport GO:0015909 13 13 1,000 4,961E-03 0,03361528 ! negative regulation of intracellular transport GO:0032387 13 13 1,000 4,961E-03 0,03349215 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 4,961E-03 0,03336992 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 4,961E-03 0,03324857 GO:0001952|regulation of cell-matrix adhesion, ! response to cytokine stimulus GO:0034097 13 13 1,000 4,961E-03 0,03312811 ! protein tetramerization GO:0051262 13 13 1,000 4,961E-03 0,03300851 ! regulation of cellular localization GO:0060341 86 85 3,000 5,211E-03 0,03454818 ! reproductive structure development GO:0048608 43 43 2,000 5,262E-03 0,03476089 ! mitochondrion organization GO:0007005 44 43 2,000 5,262E-03 0,03463674 ! homeostasis of number of cells GO:0048872 44 43 2,000 5,262E-03 0,03451348 ! positive regulation of protein kinase activity GO:0045860 89 86 3,000 5,432E-03 0,03550206 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 2,000 5,614E-03 0,03656305 ! multicellular organismal response to stress GO:0033555 14 14 1,000 5,757E-03 0,03736175 ! DNA modification GO:0006304 14 14 1,000 5,757E-03 0,03723066 ! protein amino acid acylation GO:0043543 14 14 1,000 5,757E-03 0,03710048 ! hair cycle GO:0042633 14 14 1,000 5,757E-03 0,03697121 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! response to organic cyclic substance GO:0014070 15 14 1,000 5,757E-03 0,03684284 ! positive regulation of transferase activity GO:0051347 91 88 3,000 5,893E-03 0,03757913 GO:0033674|positive regulation of kinase activity, ! regulation of DNA binding GO:0051101 47 45 2,000 5,98E-03 0,03800667 ! phosphoinositide-mediated signaling GO:0048015 45 45 2,000 5,98E-03 0,03787606 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 2,000 5,98E-03 0,03774635 ! tube morphogenesis GO:0035239 47 46 2,000 6,36E-03 0,04000793 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 2,000 6,36E-03 0,03987185 ! positive regulation of ligase activity GO:0051351 47 46 2,000 6,36E-03 0,03973669 ! cellular response to hormone stimulus GO:0032870 48 46 2,000 6,36E-03 0,03960245 ! regulation of membrane potential GO:0042391 46 46 2,000 6,36E-03 0,0394691 ! protein import into nucleus, translocation GO:0000060 15 15 1,000 6,608E-03 0,04086689 ! regulation of transcription factor import into nucleus GO:0042990 15 15 1,000 6,608E-03 0,04073021 ! striated muscle cell differentiation GO:0051146 16 15 1,000 6,608E-03 0,04059445 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 6,608E-03 0,04045958 ! ovarian follicle development GO:0001541 15 15 1,000 6,608E-03 0,04032561 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 6,608E-03 0,04019252 ! response to starvation GO:0042594 15 15 1,000 6,608E-03 0,04006031 ! leukocyte homeostasis GO:0001776 15 15 1,000 6,608E-03 0,03992896 ! negative regulation of transcription factor activity GO:0043433 16 15 1,000 6,608E-03 0,03979848 GO:0090048|negative regulation of transcription regulator activity, ! negative regulation of cell activation GO:0050866 15 15 1,000 6,608E-03 0,03966884 ! protein homooligomerization GO:0051260 15 15 1,000 6,608E-03 0,03954005 ! regulation of catabolic process GO:0009894 48 47 2,000 6,755E-03 0,04028726 ! tissue morphogenesis GO:0048729 94 93 3,000 7,157E-03 0,04254714 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 2,000 7,163E-03 0,04244853 ! DNA recombination GO:0006310 48 48 2,000 7,163E-03 0,04231248 ! epidermis development GO:0008544 94 94 3,000 7,429E-03 0,04374465 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 1,000 7,512E-03 0,04409059 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of mitosis GO:0045840 16 16 1,000 7,512E-03 0,04395062 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 1,000 7,512E-03 0,04381154 ! cellular response to reactive oxygen species GO:0034614 16 16 1,000 7,512E-03 0,04367333 ! segmentation GO:0035282 17 16 1,000 7,512E-03 0,04353599 ! positive regulation of cell development GO:0010720 16 16 1,000 7,512E-03 0,04339952 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 1,000 7,512E-03 0,04326389 ! lymphocyte proliferation GO:0046651 16 16 1,000 7,512E-03 0,04312911 ! fatty acid transport GO:0015908 16 16 1,000 7,512E-03 0,04299517 ! cellular response to nutrient levels GO:0031669 16 16 1,000 7,512E-03 0,04286206 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 1,000 7,512E-03 0,04272977 ! positive regulation of catabolic process GO:0009896 16 16 1,000 7,512E-03 0,04259829 ! ossification GO:0001503 50 49 2,000 7,586E-03 0,04288572 GO:0060348|bone development, ! skeletal muscle tissue development GO:0007519 50 49 2,000 7,586E-03 0,04275457 GO:0060538|skeletal muscle organ development, ! response to nutrient GO:0007584 49 49 2,000 7,586E-03 0,04262422 ! positive regulation of MAP kinase activity GO:0043406 50 49 2,000 7,586E-03 0,04249466 ! regulation of ligase activity GO:0051340 50 49 2,000 7,586E-03 0,04236589 ! negative regulation of transport GO:0051051 51 50 2,000 8,023E-03 0,0446729 ! T cell activation GO:0042110 51 50 2,000 8,023E-03 0,04453834 ! regulation of neurogenesis GO:0050767 51 50 2,000 8,023E-03 0,0444046 ! anatomical structure homeostasis GO:0060249 51 50 2,000 8,023E-03 0,04427165 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 8,468E-03 0,04658923 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 8,468E-03 0,04645057 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 8,468E-03 0,04631273 ! myelination GO:0042552 17 17 1,000 8,468E-03 0,04617571 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 1,000 8,468E-03 0,0460395 ! glucose transport GO:0015758 17 17 1,000 8,468E-03 0,04590409 ! development of primary male sexual characteristics GO:0046546 17 17 1,000 8,468E-03 0,04576948 ! response to toxin GO:0009636 18 17 1,000 8,468E-03 0,04563565 ! negative regulation of cell development GO:0010721 18 17 1,000 8,468E-03 0,0455026 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 8,468E-03 0,04537032 ! pigmentation GO:0043473 17 17 1,000 8,468E-03 0,04523882 ! anti-apoptosis GO:0006916 100 99 3,000 8,896E-03 0,04738319 ! ectoderm development GO:0007398 99 99 3,000 8,896E-03 0,04724664 ! muscle organ development GO:0007517 102 100 3,000 9,21E-03 0,04877584 ! response to hypoxia GO:0001666 53 53 2,000 9,423E-03 0,04976257 ! regulation of protein transport GO:0051223 53 53 2,000 9,423E-03 0,04962039 GO:0070201|regulation of establishment of protein localization, ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 1,000 9,477E-03 0,04975929 ! mononuclear cell proliferation GO:0032943 18 18 1,000 9,477E-03 0,04961793 GO:0070661|leukocyte proliferation, ! negative regulation of response to external stimulus GO:0032102 18 18 1,000 9,477E-03 0,04947737 ! hexose transport GO:0008645 18 18 1,000 9,477E-03 0,0493376 GO:0015749|monosaccharide transport, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 1,000 9,477E-03 0,04919862 ! negative regulation of DNA binding GO:0043392 19 18 1,000 9,477E-03 0,04906042 ! cellular response to extracellular stimulus GO:0031668 18 18 1,000 9,477E-03 0,048923 ! ensheathment of neurons GO:0007272 18 18 1,000 9,477E-03 0,04878634 GO:0008366|axon ensheathment, ! regulation of microtubule-based process GO:0032886 18 18 1,000 9,477E-03 0,04865045 ! negative regulation of catabolic process GO:0009895 18 18 1,000 9,477E-03 0,04851531 ! response to oxygen levels GO:0070482 55 54 2,000 9,92E-03 0,05064279 ! hormone metabolic process GO:0042445 55 54 2,000 9,92E-03 0,05050289 ! regulation of pH GO:0006885 19 19 1,000 0,01053563 0,0534908 ! feeding behavior GO:0007631 19 19 1,000 0,01053563 0,05334385 ! regulation of striated muscle tissue development GO:0016202 20 19 1,000 0,01053563 0,0531977 ! metanephros development GO:0001656 19 19 1,000 0,01053563 0,05305235 ! cellular response to oxidative stress GO:0034599 19 19 1,000 0,01053563 0,05290779 ! peripheral nervous system development GO:0007422 19 19 1,000 0,01053563 0,05276402 ! placenta development GO:0001890 19 19 1,000 0,01053563 0,05262103 ! response to heat GO:0009408 19 19 1,000 0,01053563 0,05247881 ! reproductive developmental process GO:0003006 56 56 2,000 0,0109577 0,05443406 ! extracellular structure organization GO:0043062 56 56 2,000 0,0109577 0,05428774 ! regulation of nervous system development GO:0051960 57 56 2,000 0,0109577 0,05414219 ! regulation of muscle development GO:0048634 21 20 1,000 0,01164445 0,05738161 ! negative regulation of cell adhesion GO:0007162 21 20 1,000 0,01164445 0,05722859 ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 1,000 0,01164445 0,05707639 ! positive regulation of gene-specific transcription GO:0043193 20 20 1,000 0,01164445 0,05692499 ! female gamete generation GO:0007292 20 20 1,000 0,01164445 0,0567744 ! negative regulation of neuron apoptosis GO:0043524 21 20 1,000 0,01164445 0,0566246 ! peptidyl-amino acid modification GO:0018193 61 59 2,000 0,01262869 0,06124916 ! regulation of cell development GO:0060284 60 59 2,000 0,01262869 0,0610884 ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 0,01280227 0,06176595 ! mammary gland development GO:0030879 23 21 1,000 0,01280227 0,06160468 ! regulation of protein import into nucleus GO:0042306 21 21 1,000 0,01280227 0,06144425 ! regulation of action potential in neuron GO:0019228 21 21 1,000 0,01280227 0,06128466 ! negative regulation of hydrolase activity GO:0051346 21 21 1,000 0,01280227 0,06112589 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 2,000 0,01321638 0,06294004 ! proteasomal protein catabolic process GO:0010498 62 61 2,000 0,01381953 0,06564275 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 0,01400824 0,0663681 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 0,01400824 0,06619792 ! sister chromatid segregation GO:0000819 22 22 1,000 0,01400824 0,06602862 ! odontogenesis GO:0042476 22 22 1,000 0,01400824 0,06586018 ! maintenance of protein location in cell GO:0032507 23 22 1,000 0,01400824 0,0656926 ! ovulation cycle process GO:0022602 22 22 1,000 0,01400824 0,06552586 ! spindle organization GO:0007051 22 22 1,000 0,01400824 0,06535997 ! erythrocyte differentiation GO:0030218 23 22 1,000 0,01400824 0,06519492 ! male sex differentiation GO:0046661 22 22 1,000 0,01400824 0,06503071 ! biopolymer methylation GO:0043414 22 22 1,000 0,01400824 0,06486731 GO:0032259|methylation, ! cytokinesis GO:0000910 23 22 1,000 0,01400824 0,06470474 ! axonogenesis GO:0007409 66 62 2,000 0,01443818 0,0665239 ! glucose metabolic process GO:0006006 63 63 2,000 0,01507239 0,06927283 ! response to hydrogen peroxide GO:0042542 24 23 1,000 0,0152615 0,06996754 ! regulation of hormone secretion GO:0046883 23 23 1,000 0,0152615 0,06979393 ! response to estrogen stimulus GO:0043627 23 23 1,000 0,0152615 0,06962117 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 0,0152615 0,06944926 ! positive regulation of growth GO:0045927 23 23 1,000 0,0152615 0,06927821 ! female gonad development GO:0008585 23 23 1,000 0,0152615 0,06910799 ! monovalent inorganic cation homeostasis GO:0055067 23 23 1,000 0,0152615 0,06893861 ! lipid homeostasis GO:0055088 23 23 1,000 0,0152615 0,06877005 ! calcium-mediated signaling GO:0019722 23 23 1,000 0,0152615 0,06860232 ! cell projection assembly GO:0030031 25 23 1,000 0,0152615 0,06843541 ! angiogenesis GO:0001525 65 64 2,000 0,0157222 0,07033013 ! regulation of hormone levels GO:0010817 66 65 2,000 0,01638766 0,07312944 ! regulation of action potential GO:0001508 24 24 1,000 0,01656122 0,07372545 ! erythrocyte homeostasis GO:0034101 25 24 1,000 0,01656122 0,07354779 ! ovulation cycle GO:0042698 24 24 1,000 0,01656122 0,073371 ! maintenance of protein location GO:0045185 25 24 1,000 0,01656122 0,07319505 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 0,01656122 0,07301994 ! regulation of MAP kinase activity GO:0043405 67 66 2,000 0,01706881 0,07507831 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 2,000 0,01776567 0,07795747 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! regulation of gene-specific transcription GO:0032583 25 25 1,000 0,01790657 0,0783891 ! endosome transport GO:0016197 25 25 1,000 0,01790657 0,07820335 ! development of primary female sexual characteristics GO:0046545 25 25 1,000 0,01790657 0,07801847 GO:0046660|female sex differentiation, ! regulation of T cell proliferation GO:0042129 25 25 1,000 0,01790657 0,07783446 ! positive regulation of DNA binding GO:0043388 26 25 1,000 0,01790657 0,07765132 ! negative regulation of immune system process GO:0002683 25 25 1,000 0,01790657 0,07746904 ! positive regulation of binding GO:0051099 27 26 1,000 0,01929673 0,08328777 ! glycolysis GO:0006096 26 26 1,000 0,01929673 0,08309318 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 1,000 0,01929673 0,08289949 ! induction of apoptosis by intracellular signals GO:0008629 26 26 1,000 0,01929673 0,0827067 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01929673 0,0825148 ! germ cell development GO:0007281 27 26 1,000 0,01929673 0,0823238 ! pigment metabolic process GO:0042440 26 26 1,000 0,01929673 0,08213367 ! maintenance of location in cell GO:0051651 27 26 1,000 0,01929673 0,08194442 ! synapse organization GO:0050808 26 26 1,000 0,01929673 0,08175604 ! cell part morphogenesis GO:0032990 75 70 2,000 0,01995086 0,08433357 ! ribosome biogenesis GO:0042254 71 71 2,000 0,02071086 0,0873458 ! chloride transport GO:0006821 27 27 1,000 0,0207309 0,0872307 ! energy reserve metabolic process GO:0006112 28 27 1,000 0,0207309 0,087032 ! monocarboxylic acid transport GO:0015718 27 27 1,000 0,0207309 0,0868342 ! cAMP-mediated signaling GO:0019933 27 27 1,000 0,0207309 0,0866373 ! activation of caspase activity GO:0006919 27 27 1,000 0,0207309 0,08644128 ! mesenchymal cell development GO:0014031 29 27 1,000 0,0207309 0,08624616 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 0,02148668 0,0891891 ! carbohydrate transport GO:0008643 28 28 1,000 0,02220827 0,09197718 ! histone modification GO:0016570 28 28 1,000 0,02220827 0,09177096 ! developmental growth GO:0048589 28 28 1,000 0,02220827 0,09156565 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,02220827 0,09136126 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,02372807 0,09739605 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! regulation of gene expression, epigenetic GO:0040029 29 29 1,000 0,02372807 0,09717961 ! covalent chromatin modification GO:0016569 29 29 1,000 0,02372807 0,09696414 ! adult behavior GO:0030534 30 29 1,000 0,02372807 0,09674961 ! positive regulation of protein transport GO:0051222 29 29 1,000 0,02372807 0,09653604 ! response to oxidative stress GO:0006979 76 75 2,000 0,0239092 0,09705871 ! positive regulation of peptidase activity GO:0010952 30 30 1,000 0,0252895 0,10243637 GO:0043280|positive regulation of caspase activity, ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,0252895 0,10221173 GO:0010863|positive regulation of phospholipase C activity, ! response to temperature stimulus GO:0009266 30 30 1,000 0,0252895 0,10198807 ! regulation of ossification GO:0030278 30 30 1,000 0,0252895 0,10176539 ! vesicle organization GO:0016050 30 30 1,000 0,0252895 0,10154368 ! establishment of organelle localization GO:0051656 31 30 1,000 0,0252895 0,10132293 ! cell morphogenesis involved in differentiation GO:0000904 82 77 2,000 0,02560343 0,10235819 ! regulation of protein modification process GO:0031399 79 78 2,000 0,0264743 0,10561069 ! microtubule-based movement GO:0007018 82 78 2,000 0,0264743 0,10538259 ! regulation of translational initiation GO:0006446 31 31 1,000 0,02689181 0,1068138 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,02689181 0,10658409 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,02689181 0,10635537 ! extracellular matrix organization GO:0030198 31 31 1,000 0,02689181 0,10612763 ! muscle fiber development GO:0048747 32 32 1,000 0,02853423 0,11236877 ! glucose catabolic process GO:0006007 32 32 1,000 0,02853423 0,11212918 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,02853423 0,11189061 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,02853423 0,11165305 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,02853423 0,1114165 ! kidney development GO:0001822 32 32 1,000 0,02853423 0,11118094 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,02853423 0,11094638 ! maintenance of location GO:0051235 33 32 1,000 0,02853423 0,11071281 ! lymphocyte activation GO:0046649 82 81 2,000 0,02918178 0,11298744 ! activation of protein kinase activity GO:0032147 35 33 1,000 0,03021602 0,11674658 ! regulation of neuron differentiation GO:0045664 34 33 1,000 0,03021602 0,11650234 ! blood vessel morphogenesis GO:0048514 84 83 2,000 0,03106564 0,11952815 ! regulation of angiogenesis GO:0045765 35 34 1,000 0,03193643 0,12262258 ! regulation of bone remodeling GO:0046850 34 34 1,000 0,03193643 0,12236764 ! response to metal ion GO:0010038 34 34 1,000 0,03193643 0,12211377 ! ear development GO:0043583 34 34 1,000 0,03193643 0,12186095 ! muscle cell differentiation GO:0042692 35 34 1,000 0,03193643 0,12160917 ! secondary metabolic process GO:0019748 34 34 1,000 0,03193643 0,12135843 ! negative regulation of response to stimulus GO:0048585 34 34 1,000 0,03193643 0,12110872 ! multicellular organism reproduction GO:0032504 36 35 1,000 0,03369473 0,12751415 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,03369473 0,12725285 ! regulation of tissue remodeling GO:0034103 35 35 1,000 0,03369473 0,12699262 ! inorganic anion transport GO:0015698 35 35 1,000 0,03369473 0,12673345 ! response to steroid hormone stimulus GO:0048545 35 35 1,000 0,03369473 0,12647534 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 2,000 0,03400926 0,12739647 ! hexose metabolic process GO:0019318 87 86 2,000 0,03400926 0,12713806 ! heart development GO:0007507 90 87 2,000 0,03502175 0,13065809 ! response to inorganic substance GO:0010035 36 36 1,000 0,03549021 0,13213829 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 1,000 0,03549021 0,13187188 ! regulation of mitosis GO:0007088 37 36 1,000 0,03549021 0,13160655 GO:0051783|regulation of nuclear division, ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,03549021 0,13134228 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 1,000 0,03549021 0,13107906 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 1,000 0,03549021 0,13081691 ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,03549021 0,13055579 ! gonad development GO:0008406 36 36 1,000 0,03549021 0,13029572 ! regulation of lipase activity GO:0060191 36 36 1,000 0,03549021 0,13003669 ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 0,03732214 0,13647759 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! brain development GO:0007420 91 90 2,000 0,03815259 0,13923808 ! chromosome segregation GO:0007059 38 38 1,000 0,03918983 0,14274082 ! hexose catabolic process GO:0019320 38 38 1,000 0,03918983 0,14245928 ! RNA elongation GO:0006354 38 38 1,000 0,03918983 0,14217885 ! axon guidance GO:0007411 39 38 1,000 0,03918983 0,14189952 ! regulation of homeostatic process GO:0032844 38 38 1,000 0,03918983 0,14162129 ! rRNA transcription GO:0009303 5 5 0,000 0,04075534 0,1469904 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,04075534 0,14670331 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,04075534 0,14641734 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,04075534 0,14613248 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,04075534 0,14584873 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,04075534 0,14556607 ! reproductive cellular process GO:0048610 5 5 0,000 0,04075534 0,14528452 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,04075534 0,14500404 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,04075534 0,14472465 ! water transport GO:0006833 5 5 0,000 0,04075534 0,14444634 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,04075534 0,14416909 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,04075534 0,1438929 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,04075534 0,14361777 ! glycerol metabolic process GO:0006071 5 5 0,000 0,04075534 0,14334369 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,04075534 0,14307066 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,04075534 0,14279866 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,04075534 0,14252769 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,04075534 0,14225776 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,04075534 0,14198884 ! filopodium assembly GO:0046847 7 5 0,000 0,04075534 0,14172093 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,04075534 0,14145404 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,04075534 0,14118815 ! GTP metabolic process GO:0046039 5 5 0,000 0,04075534 0,14092325 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,04075534 0,14065935 ! mRNA stabilization GO:0048255 5 5 0,000 0,04075534 0,14039644 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,04075534 0,14013451 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,04075534 0,13987355 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,04075534 0,13961356 ! social behavior GO:0035176 5 5 0,000 0,04075534 0,13935454 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,04075534 0,13909647 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,04075534 0,13883936 ! memory GO:0007613 5 5 0,000 0,04075534 0,1385832 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,04075534 0,13832798 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,04075534 0,1380737 ! erythrocyte maturation GO:0043249 5 5 0,000 0,04075534 0,13782036 ! hippocampus development GO:0021766 6 5 0,000 0,04075534 0,13756794 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,04075534 0,13731644 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,04075534 0,13706587 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,04075534 0,1368162 ! mechanosensory behavior GO:0007638 5 5 0,000 0,04075534 0,13656744 ! heart looping GO:0001947 5 5 0,000 0,04075534 0,13631959 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,04075534 0,13607264 ! response to interferon-gamma GO:0034341 5 5 0,000 0,04075534 0,13582657 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,04075534 0,1355814 ! endocrine pancreas development GO:0031018 5 5 0,000 0,04075534 0,13533711 ! pH reduction GO:0045851 5 5 0,000 0,04075534 0,1350937 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,04075534 0,13485116 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,04075534 0,13460949 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,04075534 0,13436868 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,04075534 0,13412874 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,04075534 0,13388965 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,04075534 0,13365141 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,04075534 0,13341402 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,04075534 0,13317747 ! adrenal gland development GO:0030325 5 5 0,000 0,04075534 0,13294176 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,04075534 0,13270688 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,04075534 0,13247283 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,04075534 0,1322396 ! astrocyte differentiation GO:0048708 5 5 0,000 0,04075534 0,1320072 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,04075534 0,1317756 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,04075534 0,13154482 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,04075534 0,13131485 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,04075534 0,13108568 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,04075534 0,13085731 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,04075534 0,13062973 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,04075534 0,13040294 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,04075534 0,13017694 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,04075534 0,12995172 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,04075534 0,12972728 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,04075534 0,12950361 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,04075534 0,12928071 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,04075534 0,12905858 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,04075534 0,12883721 ! response to ATP GO:0033198 5 5 0,000 0,04075534 0,1286166 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,04075534 0,12839674 ! vesicle fusion GO:0006906 5 5 0,000 0,04075534 0,12817764 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,04075534 0,12795928 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,04075534 0,12774166 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,04075534 0,12752478 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,04075534 0,12730864 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,04075534 0,12709322 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,04075534 0,12687854 ! retinol metabolic process GO:0042572 5 5 0,000 0,04075534 0,12666458 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,04075534 0,12645134 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,04075534 0,12623881 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,04075534 0,126027 ! parturition GO:0007567 5 5 0,000 0,04075534 0,1258159 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,04075534 0,12560551 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,04075534 0,12539582 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,04075534 0,12518682 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,04075534 0,12497853 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,04075534 0,12477092 ! protein heterooligomerization GO:0051291 5 5 0,000 0,04075534 0,124564 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,04075534 0,12435777 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,04075534 0,12415222 ! oligodendrocyte development GO:0014003 5 5 0,000 0,04075534 0,12394735 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,04075534 0,12374315 ! activated T cell proliferation GO:0050798 5 5 0,000 0,04075534 0,12353963 ! interaction with symbiont GO:0051702 5 5 0,000 0,04075534 0,12333677 ! cellular extravasation GO:0045123 5 5 0,000 0,04075534 0,12313458 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,04075534 0,12293305 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,04075534 0,12273218 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,04075534 0,12253197 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,04075534 0,1223324 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,04075534 0,12213349 ! response to amine stimulus GO:0014075 5 5 0,000 0,04075534 0,12193522 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,04075534 0,12173759 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,04075534 0,12154061 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,04075534 0,12134426 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,04075534 0,12114854 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,04075534 0,12095345 ! neuron recognition GO:0008038 5 5 0,000 0,04075534 0,12075899 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,04075534 0,12056516 ! decidualization GO:0046697 5 5 0,000 0,04075534 0,12037195 ! hair follicle maturation GO:0048820 5 5 0,000 0,04075534 0,12017935 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,04075534 0,11998737 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,04075534 0,119796 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,04075534 0,11960525 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,04075534 0,11941509 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,04075534 0,11922555 ! postreplication repair GO:0006301 5 5 0,000 0,04075534 0,1190366 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,04075534 0,11884825 GO:0021517|ventral spinal cord development, ! histone methylation GO:0016571 5 5 0,000 0,04075534 0,1186605 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,04075534 0,11847334 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,04075534 0,11828676 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,04075534 0,11810078 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,04075534 0,11791538 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,04075534 0,11773056 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,04075534 0,11754631 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,04075534 0,11736265 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,04075534 0,11717955 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,04075534 0,11699703 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,04075534 0,11681508 ! sterol catabolic process GO:0016127 5 5 0,000 0,04075534 0,11663369 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,04075534 0,11645286 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,04075534 0,11627259 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,04075534 0,11609288 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,04075534 0,11591373 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,04075534 0,11573512 ! zymogen activation GO:0031638 5 5 0,000 0,04075534 0,11555707 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,04075534 0,11537956 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,04075534 0,1152026 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,04075534 0,11502618 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,04075534 0,1148503 ! nucleosome positioning GO:0016584 5 5 0,000 0,04075534 0,11467495 ! regulation of isotype switching GO:0045191 5 5 0,000 0,04075534 0,11450014 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,04075534 0,11432587 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,04075534 0,11415212 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,04075534 0,1139789 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,04075534 0,1138062 ! NADPH regeneration GO:0006740 5 5 0,000 0,04075534 0,11363403 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,04075534 0,11346238 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,04075534 0,11329124 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,04075534 0,11312062 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,04075534 0,11295052 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,04075534 0,11278092 ! sarcomere organization GO:0045214 5 5 0,000 0,04075534 0,11261184 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,04075534 0,11244326 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,04075534 0,11227518 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,04075534 0,1121076 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,04075534 0,11194053 GO:0045622|regulation of T-helper cell differentiation, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,04075534 0,11177395 ! male genitalia development GO:0030539 5 5 0,000 0,04075534 0,11160787 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,04075534 0,11144228 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,04075534 0,11127718 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,04075534 0,11111257 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,04075534 0,11094844 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,04075534 0,1107848 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,04075534 0,11062164 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,04075534 0,11045896 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,04075534 0,11029676 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,04075534 0,11013504 ! ATP catabolic process GO:0006200 5 5 0,000 0,04075534 0,10997378 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,04075534 0,109813 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,04075534 0,10965269 ! blastocyst formation GO:0001825 5 5 0,000 0,04075534 0,10949285 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,04075534 0,10933347 ! embryonic gut development GO:0048566 5 5 0,000 0,04075534 0,10917456 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,04075534 0,1090161 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,04075534 0,10885811 ! activation of innate immune response GO:0002218 5 5 0,000 0,04075534 0,10870057 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,04075534 0,10854349 ! catecholamine transport GO:0051937 5 5 0,000 0,04075534 0,10838686 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,04075534 0,10823068 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,04075534 0,10807496 ! muscle adaptation GO:0043500 5 5 0,000 0,04075534 0,10791968 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,04075534 0,10776484 ! embryonic heart tube development GO:0035050 5 5 0,000 0,04075534 0,10761045 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,04075534 0,1074565 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,04075534 0,10730299 ! defense response to fungus GO:0050832 5 5 0,000 0,04075534 0,10714992 ! lysogeny GO:0030069 5 5 0,000 0,04075534 0,10699729 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,04075534 0,10684508 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,04075534 0,10669332 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,04075534 0,10654198 ! establishment of cell polarity GO:0030010 5 5 0,000 0,04075534 0,10639107 ! mitochondrion localization GO:0051646 5 5 0,000 0,04075534 0,10624059 ! nucleus localization GO:0051647 5 5 0,000 0,04075534 0,10609053 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,04075534 0,1059409 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 0,04109258 0,10666707 ! blood vessel development GO:0001568 95 94 2,000 0,04254318 0,11027719 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 0,04302969 0,11138164 ! DNA catabolic process GO:0006308 41 40 1,000 0,04302969 0,11122542 ! organelle localization GO:0051640 41 40 1,000 0,04302969 0,11106965 ! vasculature development GO:0001944 97 96 2,000 0,04483019 0,11555531 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,04500051 0,11583231 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of caspase activity GO:0043281 41 41 1,000 0,04500051 0,11567076 ! monosaccharide catabolic process GO:0046365 41 41 1,000 0,04500051 0,11550966 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,04700434 0,12048541 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,04700434 0,12031806 ! development of primary sexual characteristics GO:0045137 42 42 1,000 0,04700434 0,12015119 ! protein ubiquitination GO:0016567 43 42 1,000 0,04700434 0,11998477 ! negative regulation of ligase activity GO:0051352 43 42 1,000 0,04700434 0,11981882 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! response to protein stimulus GO:0051789 42 42 1,000 0,04700434 0,11965332 ! forebrain development GO:0030900 43 42 1,000 0,04700434 0,11948828 ! one-carbon metabolic process GO:0006730 42 42 1,000 0,04700434 0,1193237 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,04870835 0,12347936 ! axon extension GO:0048675 7 6 0,000 0,04870835 0,12330974 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,04870835 0,12314059 ! tRNA modification GO:0006400 6 6 0,000 0,04870835 0,12297191 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,04870835 0,12280368 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,04870835 0,12263592 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,04870835 0,12246861 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,04870835 0,12230176 ! virus-host interaction GO:0019048 6 6 0,000 0,04870835 0,12213536 ! regulation of S phase GO:0033261 6 6 0,000 0,04870835 0,12196942 ! myotube differentiation GO:0014902 6 6 0,000 0,04870835 0,12180392 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,04870835 0,12163888 ! bone remodeling GO:0046849 6 6 0,000 0,04870835 0,12147428 ! N-glycan processing GO:0006491 6 6 0,000 0,04870835 0,12131013 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,04870835 0,12114641 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,04870835 0,12098314 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,04870835 0,12082031 ! RNA methylation GO:0001510 6 6 0,000 0,04870835 0,12065792 ! cartilage condensation GO:0001502 7 6 0,000 0,04870835 0,12049596 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,04870835 0,12033444 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,04870835 0,12017335 GO:0050927|positive regulation of positive chemotaxis, ! succinate metabolic process GO:0006105 7 6 0,000 0,04870835 0,12001269 ! artery development GO:0060840 6 6 0,000 0,04870835 0,11985246 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,04870835 0,11969266 ! androgen metabolic process GO:0008209 6 6 0,000 0,04870835 0,11953328 ! estrogen metabolic process GO:0008210 6 6 0,000 0,04870835 0,11937433 ! limbic system development GO:0021761 7 6 0,000 0,04870835 0,11921579 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,04870835 0,11905768 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,04870835 0,11889999 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,04870835 0,11874272 ! pathogenesis GO:0009405 6 6 0,000 0,04870835 0,11858586 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,04870835 0,11842941 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,04870835 0,11827338 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,04870835 0,11811775 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,04870835 0,11796254 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,04870835 0,11780773 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,04870835 0,11765333 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,04870835 0,11749934 ! arginine metabolic process GO:0006525 6 6 0,000 0,04870835 0,11734574 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,04870835 0,11719255 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,04870835 0,11703976 ! glutamate catabolic process GO:0006538 7 6 0,000 0,04870835 0,11688736 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,04870835 0,11673536 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,04870835 0,11658376 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,04870835 0,11643255 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,04870835 0,11628173 ! V(D)J recombination GO:0033151 6 6 0,000 0,04870835 0,1161313 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,04870835 0,11598126 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,04870835 0,1158316 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,04870835 0,11568234 ! regulation of heart rate GO:0002027 6 6 0,000 0,04870835 0,11553345 ! lipid digestion GO:0044241 6 6 0,000 0,04870835 0,11538495 ! asymmetric protein localization GO:0008105 6 6 0,000 0,04870835 0,11523683 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,04870835 0,11508909 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,04870835 0,11494173 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,04870835 0,11479475 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,04870835 0,11464814 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,04870835 0,1145019 ! ruffle organization GO:0031529 6 6 0,000 0,04870835 0,11435604 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,04870835 0,11421055 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,04870835 0,11406543 ! neutral amino acid transport GO:0015804 6 6 0,000 0,04870835 0,11392068 ! L-amino acid transport GO:0015807 6 6 0,000 0,04870835 0,11377629 ! bone mineralization GO:0030282 6 6 0,000 0,04870835 0,11363227 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,04870835 0,11348861 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,04870835 0,11334532 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of bone resorption GO:0045124 6 6 0,000 0,04870835 0,11320239 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,04870835 0,11305981 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,04870835 0,1129176 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,04870835 0,11277574 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,04870835 0,11263424 ! regulation of organ growth GO:0046620 6 6 0,000 0,04870835 0,1124931 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,04870835 0,11235231 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,04870835 0,11221187 ! response to dsRNA GO:0043331 6 6 0,000 0,04870835 0,11207178 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,04870835 0,11193204 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,04870835 0,11179264 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,04870835 0,1116536 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,04870835 0,1115149 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,04870835 0,11137654 ! multicellular organismal aging GO:0010259 6 6 0,000 0,04870835 0,11123853 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,04870835 0,11110086 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,04870835 0,11096353 ! erythrocyte development GO:0048821 6 6 0,000 0,04870835 0,11082653 ! renal water homeostasis GO:0003091 6 6 0,000 0,04870835 0,11068988 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,04870835 0,11055356 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,04870835 0,11041758 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,04870835 0,11028193 ! ribosome assembly GO:0042255 6 6 0,000 0,04870835 0,11014662 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,04870835 0,11001163 ! diencephalon development GO:0021536 6 6 0,000 0,04870835 0,10987698 ! fucose catabolic process GO:0019317 6 6 0,000 0,04870835 0,10974266 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,04870835 0,10960866 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,04870835 0,10947499 ! regulation of cell division GO:0051302 6 6 0,000 0,04870835 0,10934165 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,04870835 0,10920863 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,04870835 0,10907593 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,04870835 0,10894356 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,04870835 0,10881151 ! neuroblast proliferation GO:0007405 6 6 0,000 0,04870835 0,10867977 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,04870835 0,10854836 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,04870835 0,10841726 ! regulation of glucose transport GO:0010827 6 6 0,000 0,04870835 0,10828648 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,04870835 0,10815602 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,04870835 0,10802586 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,04870835 0,10789602 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,04870835 0,1077665 ! lymph node development GO:0048535 6 6 0,000 0,04870835 0,10763728 ! organic cation transport GO:0015695 6 6 0,000 0,04870835 0,10750837 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,04870835 0,10737978 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,04870835 0,10725148 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,04870835 0,1071235 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,04870835 0,10699582 ! sperm-egg recognition GO:0035036 7 6 0,000 0,04870835 0,10686844 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,04870835 0,10674137 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,04870835 0,1066146 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,04870835 0,10648813 ! alditol metabolic process GO:0019400 6 6 0,000 0,04870835 0,10636196 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,04870835 0,10623609 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,04870835 0,10611051 ! maternal placenta development GO:0001893 6 6 0,000 0,04870835 0,10598523 ! regulation of embryonic development GO:0045995 6 6 0,000 0,04870835 0,10586025 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,04870835 0,10573556 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 1,000 0,04904055 0,10633144 ! alcohol catabolic process GO:0046164 43 43 1,000 0,04904055 0,10620649 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,04904055 0,10608184 ! humoral immune response GO:0006959 44 44 1,000 0,05110846 0,11042542 ! protein import into nucleus GO:0006606 44 44 1,000 0,05110846 0,11029612 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,05110846 0,11016712 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,05320743 0,1145576 ! nuclear import GO:0051170 45 45 1,000 0,05320743 0,11442392 ! Wnt receptor signaling pathway GO:0016055 46 45 1,000 0,05320743 0,11429056 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 1,000 0,05533684 0,11872619 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,05533684 0,11858814 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 1,000 0,05533684 0,11845041 ! respiratory burst GO:0045730 7 7 0,000 0,05659657 0,12100636 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,05659657 0,12086614 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,05659657 0,12072625 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,05659657 0,12058668 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,05659657 0,12044744 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,05659657 0,12030851 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,05659657 0,12016991 ! regulation of chemokine production GO:0032642 7 7 0,000 0,05659657 0,12003162 ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,05659657 0,11989366 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,05659657 0,11975601 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,05659657 0,11961867 GO:0043241|protein complex disassembly, ! gene silencing by RNA GO:0031047 7 7 0,000 0,05659657 0,11948165 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,05659657 0,11934495 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,05659657 0,11920855 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,05659657 0,11907247 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,05659657 0,1189367 ! axis specification GO:0009798 7 7 0,000 0,05659657 0,11880123 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,05659657 0,11866608 ! visual behavior GO:0007632 7 7 0,000 0,05659657 0,11853123 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,05659657 0,11839669 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,05659657 0,11826245 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,05659657 0,11812852 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,05659657 0,11799489 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,05659657 0,11786156 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,05659657 0,11772853 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,05659657 0,11759581 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,05659657 0,11746338 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,05659657 0,11733125 ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,05659657 0,11719942 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,05659657 0,11706788 ! protein targeting to ER GO:0045047 8 7 0,000 0,05659657 0,11693664 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,05659657 0,11680569 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,05659657 0,11667504 ! endoderm development GO:0007492 7 7 0,000 0,05659657 0,11654467 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,05659657 0,1164146 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,05659657 0,11628482 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,05659657 0,11615533 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,05659657 0,11602612 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,05659657 0,1158972 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,05659657 0,11576857 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,05659657 0,11564022 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,05659657 0,11551216 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,05659657 0,11538438 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,05659657 0,11525689 ! UV protection GO:0009650 7 7 0,000 0,05659657 0,11512967 ! DNA integration GO:0015074 7 7 0,000 0,05659657 0,11500274 ! myofibril assembly GO:0030239 7 7 0,000 0,05659657 0,11487608 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,05659657 0,11474971 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,05659657 0,11462361 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,05659657 0,11449778 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,05659657 0,11437224 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,05659657 0,11424697 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,05659657 0,11412197 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,05659657 0,11399725 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,05659657 0,1138728 GO:0019827|stem cell maintenance, ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,05659657 0,11374862 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,05659657 0,11362471 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,05659657 0,11350107 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,05659657 0,1133777 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,05659657 0,11325459 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,05659657 0,11313176 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,05659657 0,11300919 ! cranial nerve development GO:0021545 7 7 0,000 0,05659657 0,11288689 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,05659657 0,11276485 ! induction of an organ GO:0001759 7 7 0,000 0,05659657 0,11264307 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,05659657 0,11252156 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,05659657 0,1124003 ! autonomic nervous system development GO:0048483 7 7 0,000 0,05659657 0,11227931 ! intracellular lipid transport GO:0032365 7 7 0,000 0,05659657 0,11215858 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,05659657 0,11203811 ! platelet activation GO:0030168 8 7 0,000 0,05659657 0,1119179 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,05659657 0,11179794 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,05659657 0,11167825 ! natural killer cell activation GO:0030101 7 7 0,000 0,05659657 0,1115588 ! NADP metabolic process GO:0006739 7 7 0,000 0,05659657 0,11143962 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,05659657 0,11132069 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,05659657 0,11120201 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,05659657 0,11108358 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,05659657 0,11096541 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,05659657 0,11084748 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,05659657 0,11072981 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,05659657 0,11061239 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,05659657 0,11049521 ! cell-cell recognition GO:0009988 8 7 0,000 0,05659657 0,11037829 ! hormone catabolic process GO:0042447 7 7 0,000 0,05659657 0,11026161 ! dopamine metabolic process GO:0042417 7 7 0,000 0,05659657 0,11014518 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,05659657 0,11002899 ! oxygen transport GO:0015671 7 7 0,000 0,05659657 0,10991305 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,05659657 0,10979735 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,05659657 0,10968189 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,05659657 0,10956668 ! regulation of axon extension GO:0030516 7 7 0,000 0,05659657 0,10945171 ! cell killing GO:0001906 7 7 0,000 0,05659657 0,10933698 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,05659657 0,10922249 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,05659657 0,10910824 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,05659657 0,10899423 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,05659657 0,10888046 ! response to cold GO:0009409 7 7 0,000 0,05659657 0,10876693 ! regulation of blood pressure GO:0008217 48 47 1,000 0,05749605 0,11038044 ! sex differentiation GO:0007548 47 47 1,000 0,05749605 0,11026558 ! rhythmic process GO:0048511 47 47 1,000 0,05749605 0,11015096 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,05968444 0,11422475 ! protein localization in nucleus GO:0034504 48 48 1,000 0,05968444 0,11410626 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,06414633 0,12250952 ! transcription initiation GO:0006352 50 50 1,000 0,06414633 0,1223827 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,06414633 0,12225614 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,06442052 0,12265188 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,06442052 0,1225253 ! positive regulation of translation GO:0045727 8 8 0,000 0,06442052 0,12239899 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,06442052 0,12227293 ! superoxide anion generation GO:0042554 8 8 0,000 0,06442052 0,12214714 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,06442052 0,1220216 ! cGMP metabolic process GO:0046068 8 8 0,000 0,06442052 0,12189632 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,06442052 0,1217713 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,06442052 0,12164654 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,06442052 0,12152202 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,06442052 0,12139777 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,06442052 0,12127377 ! zinc ion transport GO:0006829 8 8 0,000 0,06442052 0,12115002 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,06442052 0,12102652 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,06442052 0,12090328 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,06442052 0,12078028 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,06442052 0,12065754 ! lipid localization GO:0010876 8 8 0,000 0,06442052 0,12053504 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,06442052 0,1204128 ! response to cAMP GO:0051591 8 8 0,000 0,06442052 0,1202908 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,06442052 0,12016905 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,06442052 0,12004754 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,06442052 0,11992628 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,06442052 0,11980527 ! adult walking behavior GO:0007628 8 8 0,000 0,06442052 0,11968449 ! sensory perception of taste GO:0050909 8 8 0,000 0,06442052 0,11956397 ! organelle fusion GO:0048284 8 8 0,000 0,06442052 0,11944368 ! pancreas development GO:0031016 8 8 0,000 0,06442052 0,11932364 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,06442052 0,11920383 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,06442052 0,11908427 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,06442052 0,11896495 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,06442052 0,11884586 ! sperm motility GO:0030317 8 8 0,000 0,06442052 0,11872702 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,06442052 0,11860841 ! glycine metabolic process GO:0006544 8 8 0,000 0,06442052 0,11849004 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,06442052 0,1183719 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,06442052 0,118254 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,06442052 0,11813634 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,06442052 0,1180189 ! Golgi organization GO:0007030 8 8 0,000 0,06442052 0,11790171 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,06442052 0,11778474 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,06442052 0,11766801 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,06442052 0,1175515 ! fructose metabolic process GO:0006000 8 8 0,000 0,06442052 0,11743523 ! mannose metabolic process GO:0006013 9 8 0,000 0,06442052 0,11731919 ! NAD metabolic process GO:0019674 8 8 0,000 0,06442052 0,11720337 ! sex determination GO:0007530 8 8 0,000 0,06442052 0,11708779 ! plasma membrane fusion GO:0045026 8 8 0,000 0,06442052 0,11697243 ! response to fungus GO:0009620 8 8 0,000 0,06442052 0,1168573 ! stem cell differentiation GO:0048863 8 8 0,000 0,06442052 0,1167424 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,06442052 0,11662772 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,06442052 0,11651327 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,06442052 0,11639904 ! regulation of vasodilation GO:0042312 8 8 0,000 0,06442052 0,11628503 ! vasoconstriction GO:0042310 8 8 0,000 0,06442052 0,11617125 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,06442052 0,11605769 ! muscle cell development GO:0055001 8 8 0,000 0,06442052 0,11594435 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,06442052 0,11583124 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,06442052 0,11571834 ! sensory perception of pain GO:0019233 8 8 0,000 0,06442052 0,11560567 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,06442052 0,11549321 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,06442052 0,11538097 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,06442052 0,11526895 ! chromatin silencing GO:0006342 8 8 0,000 0,06442052 0,11515715 ! tissue regeneration GO:0042246 8 8 0,000 0,06442052 0,11504556 ! salivary gland development GO:0007431 8 8 0,000 0,06442052 0,11493419 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,06442052 0,11482304 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,06442052 0,1147121 ! water homeostasis GO:0030104 8 8 0,000 0,06442052 0,11460137 ! cofactor transport GO:0051181 8 8 0,000 0,06442052 0,11449086 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,06442052 0,11438056 ! acid secretion GO:0046717 8 8 0,000 0,06442052 0,11427047 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,06442052 0,11416059 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,06442052 0,11405093 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,06442052 0,11394148 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,06442052 0,11383223 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,06442052 0,1137232 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,06442052 0,11361437 ! regulation of RNA stability GO:0043487 8 8 0,000 0,06442052 0,11350575 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,06442052 0,11339734 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,06442052 0,11328914 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,06442052 0,11318114 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,06442052 0,11307335 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,06442052 0,11296576 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,06442052 0,11285838 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,06442052 0,1127512 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,06442052 0,11264423 ! developmental induction GO:0031128 8 8 0,000 0,06442052 0,11253746 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,06442052 0,11243089 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,06442052 0,11232452 ! actin filament polymerization GO:0030041 9 8 0,000 0,06442052 0,11221835 ! peptide hormone processing GO:0016486 8 8 0,000 0,06442052 0,11211239 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,06442052 0,11200662 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,06641862 0,11537184 ! cholesterol metabolic process GO:0008203 52 52 1,000 0,0687177 0,11925303 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,0687177 0,11914084 ! carbohydrate catabolic process GO:0016052 53 53 1,000 0,07104297 0,12305657 ! regulation of T cell activation GO:0050863 53 53 1,000 0,07104297 0,12294102 ! lactation GO:0007595 10 9 0,000 0,07218071 0,12479273 ! embryonic pattern specification GO:0009880 10 9 0,000 0,07218071 0,12467577 ! positive regulation of cell size GO:0045793 9 9 0,000 0,07218071 0,12455904 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,07218071 0,12444252 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,07218071 0,12432621 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,07218071 0,12421013 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,07218071 0,12409426 ! viral genome replication GO:0019079 9 9 0,000 0,07218071 0,12397861 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,07218071 0,12386317 ! copper ion transport GO:0006825 9 9 0,000 0,07218071 0,12374795 ! lipid phosphorylation GO:0046834 9 9 0,000 0,07218071 0,12363295 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,07218071 0,12351815 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,07218071 0,12340357 ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,07218071 0,1232892 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,07218071 0,12317505 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,07218071 0,1230611 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,07218071 0,12294737 ! phospholipid efflux GO:0033700 9 9 0,000 0,07218071 0,12283384 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,07218071 0,12272053 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,07218071 0,12260742 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,07218071 0,12249452 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,07218071 0,12238183 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,07218071 0,12226935 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,07218071 0,12215707 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,07218071 0,122045 ! methionine metabolic process GO:0006555 9 9 0,000 0,07218071 0,12193313 ! glutamine metabolic process GO:0006541 9 9 0,000 0,07218071 0,12182147 ! cerebral cortex development GO:0021987 9 9 0,000 0,07218071 0,12171002 ! response to osmotic stress GO:0006970 9 9 0,000 0,07218071 0,12159877 ! pigmentation during development GO:0048066 9 9 0,000 0,07218071 0,12148772 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,07218071 0,12137687 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,07218071 0,12126623 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,07218071 0,12115578 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,07218071 0,12104554 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,07218071 0,1209355 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,07218071 0,12082566 ! L-glutamate transport GO:0015813 9 9 0,000 0,07218071 0,12071602 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,07218071 0,12060657 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,07218071 0,12049733 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,07218071 0,12038828 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,07218071 0,12027943 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,07218071 0,12017078 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,07218071 0,12006232 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,07218071 0,11995406 ! DNA replication initiation GO:0006270 9 9 0,000 0,07218071 0,11984599 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,07218071 0,11973812 GO:0006692|prostanoid metabolic process, ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,07218071 0,11963044 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,07218071 0,11952296 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,07218071 0,11941566 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,07218071 0,11930856 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,07218071 0,11920166 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,07218071 0,11909494 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,07218071 0,11898842 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,07218071 0,11888208 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,07218071 0,11877594 ! collagen catabolic process GO:0030574 9 9 0,000 0,07218071 0,11866998 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,07218071 0,11856422 ! purine base metabolic process GO:0006144 9 9 0,000 0,07218071 0,11845864 ! gas transport GO:0015669 9 9 0,000 0,07218071 0,11835325 ! cholesterol efflux GO:0033344 9 9 0,000 0,07218071 0,11824804 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,07218071 0,11814303 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,07218071 0,1180382 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,07218071 0,11793355 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,07218071 0,1178291 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 0,000 0,07218071 0,11772482 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,07218071 0,11762073 ! actin filament-based movement GO:0030048 9 9 0,000 0,07218071 0,11751683 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,07218071 0,11741311 ! response to virus GO:0009615 54 54 1,000 0,07339386 0,11928121 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,07339386 0,11917611 ! in utero embryonic development GO:0001701 55 55 1,000 0,07576981 0,12292585 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,07576981 0,12281774 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,07987765 0,12936249 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,07987765 0,12924892 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,07987765 0,12913554 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,07987765 0,12902236 ! neuron maturation GO:0042551 10 10 0,000 0,07987765 0,12890938 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,07987765 0,1287966 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,07987765 0,12868402 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,07987765 0,12857163 ! hormone secretion GO:0046879 10 10 0,000 0,07987765 0,12845944 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,07987765 0,12834744 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,07987765 0,12823564 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,07987765 0,12812404 ! cAMP metabolic process GO:0046058 10 10 0,000 0,07987765 0,12801262 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,07987765 0,1279014 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,07987765 0,12779038 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,07987765 0,12767955 ! glial cell development GO:0021782 10 10 0,000 0,07987765 0,12756891 ! phototransduction GO:0007602 11 10 0,000 0,07987765 0,12745846 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,07987765 0,1273482 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,07987765 0,12723813 ! myoblast differentiation GO:0045445 10 10 0,000 0,07987765 0,12712825 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,07987765 0,12701857 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,07987765 0,12690907 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,07987765 0,12679976 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,07987765 0,12669063 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,07987765 0,1265817 ! protein polyubiquitination GO:0000209 10 10 0,000 0,07987765 0,12647295 ! glutamate metabolic process GO:0006536 11 10 0,000 0,07987765 0,12636439 ! plasma membrane organization GO:0007009 10 10 0,000 0,07987765 0,12625602 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,07987765 0,12614783 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,07987765 0,12603983 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,07987765 0,12593201 GO:0030968|endoplasmic reticulum unfolded protein response, ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,07987765 0,12582437 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,07987765 0,12571692 ! exocrine system development GO:0035272 10 10 0,000 0,07987765 0,12560966 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,07987765 0,12550257 ! embryo implantation GO:0007566 11 10 0,000 0,07987765 0,12539567 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,07987765 0,12528895 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,07987765 0,12518241 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,07987765 0,12507606 ! protein export from nucleus GO:0006611 10 10 0,000 0,07987765 0,12496988 ! negative regulation of immune response GO:0050777 10 10 0,000 0,07987765 0,12486388 ! cytolysis GO:0019835 10 10 0,000 0,07987765 0,12475807 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,07987765 0,12465243 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,07987765 0,12454697 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,07987765 0,12444169 ! histone deacetylation GO:0016575 10 10 0,000 0,07987765 0,12433659 ! mRNA splice site selection GO:0006376 11 10 0,000 0,07987765 0,12423166 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,07987765 0,12412691 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,07987765 0,12402234 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,07987765 0,12391794 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,07987765 0,12381372 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,07987765 0,12370968 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,07987765 0,12360581 ! regulation of epidermis development GO:0045682 10 10 0,000 0,07987765 0,12350211 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,07987765 0,12339859 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,07987765 0,12329524 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,07987765 0,12319206 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,07987765 0,12308906 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,07987765 0,12298623 ! nerve development GO:0021675 10 10 0,000 0,07987765 0,12288357 ! epithelial to mesenchymal transition GO:0001837 10 10 0,000 0,07987765 0,12278108 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,07987765 0,12267876 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,07987765 0,12257662 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,07987765 0,12247464 ! innate immune response GO:0045087 58 58 1,000 0,08304245 0,12722131 ! carboxylic acid transport GO:0046942 59 59 1,000 0,08551311 0,13089756 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 1,000 0,08551311 0,13078893 ! protein localization in organelle GO:0033365 59 59 1,000 0,08551311 0,13068048 ! immune effector process GO:0002252 59 59 1,000 0,08551311 0,13057221 ! protein secretion GO:0009306 11 11 0,000 0,08751186 0,13351354 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,08751186 0,1334031 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,08751186 0,13329285 ! negative regulation of defense response GO:0031348 11 11 0,000 0,08751186 0,13318279 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,08751186 0,1330729 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,08751186 0,13296319 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,08751186 0,13285367 ! skin development GO:0043588 11 11 0,000 0,08751186 0,13274432 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,08751186 0,13263516 ! peroxisomal transport GO:0043574 11 11 0,000 0,08751186 0,13252617 ! protein amino acid methylation GO:0006479 11 11 0,000 0,08751186 0,13241737 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,08751186 0,13230874 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,08751186 0,13220029 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,08751186 0,13209202 ! T cell proliferation GO:0042098 11 11 0,000 0,08751186 0,13198392 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,08751186 0,131876 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,08751186 0,13176826 ! spinal cord development GO:0021510 11 11 0,000 0,08751186 0,1316607 ! smooth muscle contraction GO:0006939 11 11 0,000 0,08751186 0,13155331 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,08751186 0,13144609 ! digestive system process GO:0022600 11 11 0,000 0,08751186 0,13133905 ! mitotic spindle organization GO:0007052 11 11 0,000 0,08751186 0,13123218 ! fucose metabolic process GO:0006004 11 11 0,000 0,08751186 0,13112549 ! membrane budding GO:0006900 11 11 0,000 0,08751186 0,13101897 ! apoptotic nuclear changes GO:0030262 11 11 0,000 0,08751186 0,13091262 ! monoamine transport GO:0015844 11 11 0,000 0,08751186 0,13080645 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,08751186 0,13070045 ! body fluid secretion GO:0007589 11 11 0,000 0,08751186 0,13059462 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,08751186 0,13048896 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,08751186 0,13038347 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,08751186 0,13027815 ! membrane depolarization GO:0051899 11 11 0,000 0,08751186 0,130173 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,08751186 0,13006803 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,08751186 0,12996322 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,08751186 0,12985858 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,08751186 0,12975411 ! vitamin transport GO:0051180 11 11 0,000 0,08751186 0,1296498 ! muscle maintenance GO:0046716 12 11 0,000 0,08751186 0,12954566 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,08751186 0,1294417 ! steroid catabolic process GO:0006706 11 11 0,000 0,08751186 0,12933789 ! endocrine process GO:0050886 11 11 0,000 0,08751186 0,12923426 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,08751186 0,12913079 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,08751186 0,12902748 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,08751186 0,12892434 ! protein polymerization GO:0051258 65 60 1,000 0,0880061 0,12954892 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,0905209 0,13314447 ! lipid transport GO:0006869 62 62 1,000 0,09305699 0,13676558 ! protein import GO:0017038 62 62 1,000 0,09305699 0,1366566 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,09305699 0,1365478 ! translational initiation GO:0006413 12 12 0,000 0,09508382 0,13941089 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,09508382 0,13930007 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,09508382 0,13918942 ! initiation of viral infection GO:0019059 12 12 0,000 0,09508382 0,13907895 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,09508382 0,13896866 ! iron ion transport GO:0006826 13 12 0,000 0,09508382 0,13885854 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,09508382 0,1387486 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,09508382 0,13863883 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,09508382 0,13852924 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,09508382 0,13841981 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,09508382 0,13831056 ! collagen metabolic process GO:0032963 12 12 0,000 0,09508382 0,13820149 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,09508382 0,13809258 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,09508382 0,13798385 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,09508382 0,13787528 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,09508382 0,13776689 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,09508382 0,13765867 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,09508382 0,13755061 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,09508382 0,13744273 ! actomyosin structure organization GO:0031032 12 12 0,000 0,09508382 0,13733502 ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,09508382 0,13722747 ! retinoid metabolic process GO:0001523 12 12 0,000 0,09508382 0,1371201 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,09508382 0,13701289 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,09508382 0,13690585 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,09508382 0,13679897 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,09508382 0,13669226 ! acute-phase response GO:0006953 12 12 0,000 0,09508382 0,13658572 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,09508382 0,13647935 ! vacuolar transport GO:0007034 12 12 0,000 0,09508382 0,13637314 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,09508382 0,13626709 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,09508382 0,13616121 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,09508382 0,1360555 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,09508382 0,13594995 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,09508382 0,13584456 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,09508382 0,13573934 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,09508382 0,13563427 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,09508382 0,13552938 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,09508382 0,13542464 ! pallium development GO:0021543 13 12 0,000 0,09508382 0,13532006 ! cell fate determination GO:0001709 12 12 0,000 0,09508382 0,13521565 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,09508382 0,1351114 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,09508382 0,13500731 ! detection of light stimulus GO:0009583 13 12 0,000 0,09508382 0,13490337 ! synaptogenesis GO:0007416 12 12 0,000 0,09508382 0,1347996 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,09508382 0,13469599 ! hormone transport GO:0009914 12 12 0,000 0,09508382 0,13459254 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,09508382 0,13448924 ! heme biosynthetic process GO:0006783 12 12 0,000 0,09508382 0,13438611 ! spermatid differentiation GO:0048515 13 12 0,000 0,09508382 0,13428313 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,09508382 0,13418031 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,09508382 0,13407765 ! neural tube closure GO:0001843 13 12 0,000 0,09508382 0,13397514 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of secretion GO:0051046 65 63 1,000 0,09561386 0,13461906 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,09561386 0,1345163 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,09819101 0,13803664 ! regulation of cytoskeleton organization GO:0051493 66 64 1,000 0,09819101 0,13793143 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,09819101 0,13782638 ! anion transport GO:0006820 65 65 1,000 0,10078795 0,14136391 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,10078795 0,14125641 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,10259405 0,14367844 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,10259405 0,14356934 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,10259405 0,14346042 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,10259405 0,14335165 ! phenol metabolic process GO:0018958 13 13 0,000 0,10259405 0,14324305 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,10259405 0,14313462 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,10259405 0,14302634 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,10259405 0,14291824 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,10259405 0,14281029 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,10259405 0,14270251 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,10259405 0,14259489 ! keratinization GO:0031424 13 13 0,000 0,10259405 0,14248744 ! patterning of blood vessels GO:0001569 13 13 0,000 0,10259405 0,14238014 ! vasculogenesis GO:0001570 13 13 0,000 0,10259405 0,14227301 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,10259405 0,14216604 ! regulation of innate immune response GO:0045088 13 13 0,000 0,10259405 0,14205922 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,10259405 0,14195257 ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,10259405 0,14184608 ! autophagy GO:0006914 13 13 0,000 0,10259405 0,14173975 ! regulation of endothelial cell migration GO:0010594 13 13 0,000 0,10259405 0,14163358 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,10259405 0,14152757 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,10259405 0,14142171 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,10259405 0,14131601 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! nucleobase metabolic process GO:0009112 13 13 0,000 0,10259405 0,14121048 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,10259405 0,14110509 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,10259405 0,14099987 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,10259405 0,1408948 ! vasodilation GO:0042311 14 13 0,000 0,10259405 0,14078989 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,10259405 0,14068514 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,10259405 0,14058054 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,10259405 0,1404761 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,10259405 0,14037181 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,10259405 0,14026768 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,10259405 0,1401637 ! immunoglobulin production GO:0002377 13 13 0,000 0,10259405 0,14005987 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,10259405 0,1399562 ! cell-cell junction organization GO:0045216 13 13 0,000 0,10259405 0,13985268 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,10259405 0,13974932 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,10259405 0,13964611 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,10259405 0,13954305 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,10259405 0,13944014 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,10259405 0,13933738 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,10259405 0,13923478 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,10259405 0,13913232 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,10259405 0,13903002 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,10259405 0,13892787 ! blastocyst development GO:0001824 13 13 0,000 0,10259405 0,13882586 ! telomere organization GO:0032200 13 13 0,000 0,10259405 0,13872401 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,10259405 0,13862231 ! regulation of amine transport GO:0051952 13 13 0,000 0,10259405 0,13852075 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,10259405 0,13841935 ! negative regulation of cell differentiation GO:0045596 68 67 1,000 0,1060392 0,14296287 ! neuron fate commitment GO:0048663 14 14 0,000 0,11004303 0,14825241 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,11004303 0,14814412 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,11004303 0,14803598 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,11004303 0,14792801 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,11004303 0,14782019 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,11004303 0,14771252 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,11004303 0,14760502 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,11004303 0,14749767 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,11004303 0,14739048 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,11004303 0,14728344 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,11004303 0,14717656 ! vesicle docking GO:0048278 14 14 0,000 0,11004303 0,14706983 ! superoxide metabolic process GO:0006801 15 14 0,000 0,11004303 0,14696326 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,11004303 0,14685684 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,11004303 0,14675058 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,11004303 0,14664447 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,11004303 0,14653851 ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,11004303 0,1464327 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,11004303 0,14632705 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,11004303 0,14622155 GO:0033189|response to vitamin A, ! lysosome organization GO:0007040 14 14 0,000 0,11004303 0,14611621 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,11004303 0,14601101 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,11004303 0,14590597 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,11004303 0,14580108 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,11004303 0,14569633 ! primary neural tube formation GO:0014020 15 14 0,000 0,11004303 0,14559174 ! peptide cross-linking GO:0018149 14 14 0,000 0,11004303 0,1454873 ! regulation of behavior GO:0050795 14 14 0,000 0,11004303 0,14538301 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,11004303 0,14527887 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,11004303 0,14517487 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,11004303 0,14507103 ! formation of primary germ layer GO:0001704 14 14 0,000 0,11004303 0,14496733 GO:0001707|mesoderm formation, ! collagen fibril organization GO:0030199 14 14 0,000 0,11004303 0,14486378 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,11004303 0,14476038 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,11004303 0,14465713 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,11004303 0,14455402 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,11004303 0,14445107 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,11004303 0,14434825 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,11004303 0,14424559 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,11004303 0,14414307 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,11004303 0,14404069 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,11004303 0,14393846 ! regionalization GO:0003002 70 69 1,000 0,11136378 0,14556273 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,11136378 0,14545957 ! positive regulation of transport GO:0051050 71 70 1,000 0,1140524 0,14886584 ! wound healing GO:0042060 74 70 1,000 0,1140524 0,14876048 ! growth GO:0040007 70 70 1,000 0,1140524 0,14865528 ! translational elongation GO:0006414 71 71 1,000 0,11675795 0,15207413 ! calcium ion homeostasis GO:0055074 71 71 1,000 0,11675795 0,15196673 GO:0006874|cellular calcium ion homeostasis, ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,11675795 0,15185949 ! regulation of cell activation GO:0050865 71 71 1,000 0,11675795 0,1517524 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,11743125 0,15251994 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,11743125 0,15241253 ! positive regulation of ossification GO:0045778 15 15 0,000 0,11743125 0,15230527 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,11743125 0,15219817 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,11743125 0,15209121 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,11743125 0,15198441 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,11743125 0,15187775 ! response to vitamin GO:0033273 15 15 0,000 0,11743125 0,15177124 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,11743125 0,15166489 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,11743125 0,15155868 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,11743125 0,15145262 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,11743125 0,15134671 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,11743125 0,15124095 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,11743125 0,15113533 ! heme metabolic process GO:0042168 15 15 0,000 0,11743125 0,15102986 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,11743125 0,15092454 ! chromosome condensation GO:0030261 15 15 0,000 0,11743125 0,15081937 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,11743125 0,15071434 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,11743125 0,15060946 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,11743125 0,15050472 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,11743125 0,15040013 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,11743125 0,15029569 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,11743125 0,15019139 ! phospholipid transport GO:0015914 15 15 0,000 0,11743125 0,15008723 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,11743125 0,14998322 ! glutathione metabolic process GO:0006749 16 15 0,000 0,11743125 0,14987936 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,11743125 0,14977564 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,11743125 0,14967206 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,11743125 0,14956862 ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,11743125 0,14946533 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,11743125 0,14936218 ! sensory organ development GO:0007423 72 72 1,000 0,11947998 0,15186318 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,12475921 0,15846397 ! alkaloid metabolic process GO:0009820 16 16 0,000 0,12475921 0,15835483 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,12475921 0,15824585 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,12475921 0,15813701 ! learning GO:0007612 16 16 0,000 0,12475921 0,15802833 ! circadian rhythm GO:0007623 16 16 0,000 0,12475921 0,15791979 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,12475921 0,1578114 ! vacuole organization GO:0007033 16 16 0,000 0,12475921 0,15770317 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,12475921 0,15759508 ! vesicle targeting GO:0006903 17 16 0,000 0,12475921 0,15748713 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,12475921 0,15737934 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,12475921 0,15727169 ! iron ion homeostasis GO:0055072 16 16 0,000 0,12475921 0,15716419 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,12475921 0,15705684 ! cell fate specification GO:0001708 16 16 0,000 0,12475921 0,15694964 ! pentose metabolic process GO:0019321 16 16 0,000 0,12475921 0,15684258 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,12475921 0,15673566 ! cofactor catabolic process GO:0051187 16 16 0,000 0,12475921 0,15662889 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,12475921 0,15652227 ! polyol metabolic process GO:0019751 16 16 0,000 0,12475921 0,15641579 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,12475921 0,15630946 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,12475921 0,15620327 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,12475921 0,15609723 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,12475921 0,15599133 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,12475921 0,15588557 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,12475921 0,15577996 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,12475921 0,15567449 ! regulation of coagulation GO:0050818 17 16 0,000 0,12475921 0,15556916 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,13052414 0,16264773 ! positive regulation of multicellular organismal process GO:0051240 76 76 1,000 0,13052414 0,16253783 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,13202738 0,16429875 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,13202738 0,16418789 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,13202738 0,16407718 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,13202738 0,16396661 ! leukocyte adhesion GO:0007159 17 17 0,000 0,13202738 0,1638562 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,13202738 0,16374593 ! sensory perception of smell GO:0007608 17 17 0,000 0,13202738 0,16363581 ! tissue remodeling GO:0048771 17 17 0,000 0,13202738 0,16352584 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,13202738 0,16341602 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,13202738 0,16330635 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,13202738 0,16319682 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,13202738 0,16308744 ! neural crest cell development GO:0014032 19 17 0,000 0,13202738 0,1629782 GO:0014033|neural crest cell differentiation, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,13202738 0,16286911 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,13202738 0,16276017 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,13202738 0,16265137 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,13202738 0,16254272 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,13202738 0,16243422 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,13202738 0,16232585 ! adult locomotory behavior GO:0008344 17 17 0,000 0,13202738 0,16221764 ! embryonic organ development GO:0048568 17 17 0,000 0,13202738 0,16210956 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,13202738 0,16200163 ! liver development GO:0001889 17 17 0,000 0,13202738 0,16189385 ! gene silencing GO:0016458 17 17 0,000 0,13202738 0,16178621 ! cellular metal ion homeostasis GO:0006875 77 77 1,000 0,13332202 0,16326411 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,13613381 0,16659668 ! metal ion homeostasis GO:0055065 78 78 1,000 0,13613381 0,16648613 ! nuclear transport GO:0051169 79 79 1,000 0,13895907 0,16982863 GO:0006913|nucleocytoplasmic transport, ! mRNA export from nucleus GO:0006406 18 18 0,000 0,13923624 0,1700546 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,13923624 0,16994198 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,13923624 0,16982951 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,13923624 0,16971719 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,13923624 0,16960502 ! membrane docking GO:0022406 18 18 0,000 0,13923624 0,16949299 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,13923624 0,16938112 ! response to calcium ion GO:0051592 18 18 0,000 0,13923624 0,16926939 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,13923624 0,16915781 GO:0055092|sterol homeostasis, ! striated muscle contraction GO:0006941 18 18 0,000 0,13923624 0,16904637 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,13923624 0,16893508 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,13923624 0,16882394 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,13923624 0,16871295 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! telencephalon development GO:0021537 19 18 0,000 0,13923624 0,1686021 ! hexose biosynthetic process GO:0019319 18 18 0,000 0,13923624 0,16849139 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,13923624 0,16838084 ! BMP signaling pathway GO:0030509 18 18 0,000 0,13923624 0,16827042 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,13923624 0,16816015 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,13923624 0,16805003 ! MAPKKK cascade GO:0000165 82 81 1,000 0,14464845 0,17446799 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,14638628 0,1764486 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,14638628 0,17633327 GO:0006956|complement activation, ! glial cell differentiation GO:0010001 19 19 0,000 0,14638628 0,1762181 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,14638628 0,17610307 ! regulation of endothelial cell proliferation GO:0001936 19 19 0,000 0,14638628 0,1759882 ! peroxisome organization GO:0007031 19 19 0,000 0,14638628 0,17587347 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,14638628 0,1757589 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,14638628 0,17564447 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 0,000 0,14638628 0,17553019 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,14638628 0,17541606 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,14638628 0,17530208 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,14638628 0,17518825 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,14638628 0,17507457 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,14638628 0,17496103 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,14638628 0,17484764 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,14638628 0,17473439 ! eye morphogenesis GO:0048592 19 19 0,000 0,14638628 0,1746213 ! regulation of cell shape GO:0008360 21 19 0,000 0,14638628 0,17450835 ! vesicle localization GO:0051648 20 19 0,000 0,14638628 0,17439554 ! establishment or maintenance of cell polarity GO:0007163 21 20 0,000 0,15347795 0,18272601 ! organic ether metabolic process GO:0018904 20 20 0,000 0,15347795 0,18260805 GO:0006662|glycerol ether metabolic process, ! neural tube development GO:0021915 21 20 0,000 0,15347795 0,18249023 ! nucleus organization GO:0006997 20 20 0,000 0,15347795 0,18237257 ! phagocytosis GO:0006909 21 20 0,000 0,15347795 0,18225507 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,15347795 0,18213771 ! protein targeting to membrane GO:0006612 22 20 0,000 0,15347795 0,1820205 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,15347795 0,18190345 ! chromatin remodeling GO:0006338 20 20 0,000 0,15347795 0,18178654 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,15347795 0,18166979 ! peptidyl-tyrosine modification GO:0018212 21 20 0,000 0,15347795 0,18155319 ! lipid oxidation GO:0034440 20 20 0,000 0,15347795 0,18143673 GO:0019395|fatty acid oxidation, ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,15347795 0,18132042 ! RNA modification GO:0009451 20 20 0,000 0,15347795 0,18120427 ! single fertilization GO:0007338 21 20 0,000 0,15347795 0,18108826 ! regulation of B cell activation GO:0050864 20 20 0,000 0,15347795 0,1809724 ! mRNA catabolic process GO:0006402 21 21 0,000 0,16051173 0,18914522 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,16051173 0,18902436 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,16051173 0,18890366 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,16051173 0,18878311 ! Notch signaling pathway GO:0007219 22 21 0,000 0,16051173 0,18866271 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,16051173 0,18854246 ! ear morphogenesis GO:0042471 21 21 0,000 0,16051173 0,18842237 ! organic anion transport GO:0015711 21 21 0,000 0,16051173 0,18830244 ! cholesterol transport GO:0030301 21 21 0,000 0,16051173 0,18818265 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,16051173 0,18806302 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,16051173 0,18794354 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,16051173 0,18782421 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,16051173 0,18770503 ! regulation of proteolysis GO:0030162 21 21 0,000 0,16051173 0,187586 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,16051173 0,18746713 ! male gamete generation GO:0048232 90 88 1,000 0,16492827 0,19250336 GO:0007283|spermatogenesis, ! RNA export from nucleus GO:0006405 22 22 0,000 0,16748809 0,19536744 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,16748809 0,19524387 ! regulation of ion transport GO:0043269 22 22 0,000 0,16748809 0,19512045 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,16748809 0,19499719 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,16748809 0,19487409 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,16748809 0,19475114 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,16748809 0,19462834 ! cell chemotaxis GO:0060326 23 22 0,000 0,16748809 0,1945057 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,16748809 0,19438322 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,16748809 0,19426089 ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,16748809 0,19413871 ! detection of external stimulus GO:0009581 23 22 0,000 0,16748809 0,19401669 ! neuron migration GO:0001764 22 22 0,000 0,16748809 0,19389482 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,16748809 0,1937731 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,16748809 0,19365154 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,16748809 0,19353013 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,16748809 0,19340887 ! aerobic respiration GO:0009060 22 22 0,000 0,16748809 0,19328776 ! cytokine production GO:0001816 22 22 0,000 0,16748809 0,1931668 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,16748809 0,193046 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 1,000 0,16786701 0,19336181 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 1,000 0,17377209 0,2000387 ! viral infectious cycle GO:0019058 23 23 0,000 0,17440748 0,20064481 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,17440748 0,20051964 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,17440748 0,20039463 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,17440748 0,20026977 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,17440748 0,20014507 ! endocrine system development GO:0035270 23 23 0,000 0,17440748 0,20002053 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,17440748 0,19989614 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,17440748 0,1997719 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,17440748 0,19964782 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,17673776 0,20218975 ! gliogenesis GO:0042063 24 24 0,000 0,18127036 0,20724645 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,18127036 0,20711797 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,18127036 0,20698964 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,18127036 0,20686147 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,18127036 0,20673346 ! fertilization GO:0009566 25 24 0,000 0,18127036 0,20660561 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,18127036 0,20647792 ! glucan metabolic process GO:0044042 25 24 0,000 0,18127036 0,20635039 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! pattern specification process GO:0007389 96 94 1,000 0,18269364 0,20784221 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,18807719 0,21383483 ! negative regulation of secretion GO:0051048 26 25 0,000 0,18807719 0,21370299 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,18807719 0,21357132 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,18807719 0,21343981 ! cellular component disassembly GO:0022411 26 25 0,000 0,18807719 0,21330846 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,18807719 0,21317728 ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,18807719 0,21304625 ! excretion GO:0007588 25 25 0,000 0,18807719 0,21291539 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,18807719 0,21278469 ! gastrulation GO:0007369 25 25 0,000 0,18807719 0,21265414 ! heart morphogenesis GO:0003007 25 25 0,000 0,18807719 0,21252376 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,18807719 0,21239354 ! regulation of endocytosis GO:0030100 25 25 0,000 0,18807719 0,21226348 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,18807719 0,21213357 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,18807719 0,21200383 ! blood circulation GO:0008015 99 98 1,000 0,19469449 0,21932881 GO:0003013|circulatory system process, ! endocytosis GO:0006897 99 98 1,000 0,19469449 0,21919483 GO:0010324|membrane invagination, ! regulation of system process GO:0044057 98 98 1,000 0,19469449 0,21906101 ! positive regulation of defense response GO:0031349 26 26 0,000 0,1948284 0,21907794 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,1948284 0,21894436 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,1948284 0,21881094 ! cellular defense response GO:0006968 26 26 0,000 0,1948284 0,21867768 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,1948284 0,21854458 ! regulation of protein secretion GO:0050708 26 26 0,000 0,1948284 0,21841165 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,1948284 0,21827888 GO:0035150|regulation of tube size, ! response to other organism GO:0051707 101 100 1,000 0,20073438 0,22475909 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,20152446 0,22550673 ! learning or memory GO:0007611 28 27 0,000 0,20152446 0,22536989 ! peptide metabolic process GO:0006518 29 27 0,000 0,20152446 0,22523322 ! inner ear development GO:0048839 27 27 0,000 0,20152446 0,22509672 ! defense response to bacterium GO:0042742 27 27 0,000 0,20152446 0,22496038 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,20152446 0,2248242 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,20152446 0,22468819 ! cell growth GO:0016049 27 27 0,000 0,20152446 0,22455235 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,2081658 0,23181243 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,2081658 0,23167245 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,2081658 0,23153263 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,2081658 0,23139299 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,2081658 0,23125351 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,2081658 0,2311142 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,2081658 0,23097506 ! cartilage development GO:0051216 29 28 0,000 0,2081658 0,23083609 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,21475287 0,23799731 ! viral reproductive process GO:0022415 29 29 0,000 0,21475287 0,23785429 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,21475287 0,23771143 ! leukocyte migration GO:0050900 30 29 0,000 0,21475287 0,23756875 ! antigen processing and presentation GO:0019882 29 29 0,000 0,21475287 0,23742623 ! tRNA processing GO:0008033 29 29 0,000 0,21475287 0,23728389 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,21475287 0,23714172 ! transition metal ion transport GO:0000041 31 30 0,000 0,22128608 0,24420973 ! RNA catabolic process GO:0006401 30 30 0,000 0,22128608 0,24406359 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,22128608 0,24391762 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,22128608 0,24377182 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,22128608 0,2436262 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,22128608 0,24348075 ! positive regulation of response to external stimulus GO:0032103 30 30 0,000 0,22128608 0,24333547 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,22128608 0,24319037 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,22128608 0,24304544 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,22128608 0,24290069 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,22128608 0,2427561 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,22128608 0,24261169 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,22128608 0,24246745 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,22128608 0,24232338 ! membrane fusion GO:0006944 31 31 0,000 0,22776589 0,24927111 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,22776589 0,24912317 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,22776589 0,24897541 ! ion transmembrane transport GO:0034220 31 31 0,000 0,22776589 0,24882783 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,22776589 0,24868042 ! digestion GO:0007586 31 31 0,000 0,22776589 0,24853318 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,22776589 0,24838612 ! regulation of heart contraction GO:0008016 31 31 0,000 0,22776589 0,24823923 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,22776589 0,24809252 ! camera-type eye development GO:0043010 31 31 0,000 0,22776589 0,24794598 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,22776589 0,24779961 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,22776589 0,24765342 ! cell redox homeostasis GO:0045454 32 32 0,000 0,23419272 0,25449127 ! lipid modification GO:0030258 32 32 0,000 0,23419272 0,2543413 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,23419272 0,25419151 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,23419272 0,2540419 ! nuclear export GO:0051168 32 32 0,000 0,23419272 0,25389246 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,23419272 0,2537432 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,24056699 0,26049646 ! amino acid transport GO:0006865 33 33 0,000 0,24056699 0,26034349 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,24056699 0,26019071 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,24056699 0,26003811 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,24056699 0,25988568 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,24056699 0,25973343 ! regulation of actin filament length GO:0030832 34 34 0,000 0,24688913 0,2664032 ! cellular polysaccharide metabolic process GO:0044264 35 34 0,000 0,24688913 0,26624732 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,24688913 0,26609162 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,24688913 0,2659361 ! viral reproduction GO:0016032 34 34 0,000 0,24688913 0,26578077 ! detection of stimulus GO:0051606 36 34 0,000 0,24688913 0,26562561 ! acute inflammatory response GO:0002526 35 35 0,000 0,25315956 0,27221299 ! regulation of cellular component size GO:0032535 35 35 0,000 0,25315956 0,27205426 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,25315956 0,27189572 ! mesoderm development GO:0007498 35 35 0,000 0,25315956 0,27173737 ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,25315956 0,2715792 ! regulation of immune effector process GO:0002697 35 35 0,000 0,25315956 0,27142121 ! hydrogen transport GO:0006818 36 36 0,000 0,25937868 0,27792727 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,25937868 0,27776578 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,25937868 0,27760448 GO:0035113|embryonic appendage morphogenesis, ! heterocycle catabolic process GO:0046700 36 36 0,000 0,25937868 0,27744336 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,25937868 0,27728243 ! activation of immune response GO:0002253 36 36 0,000 0,25937868 0,27712169 ! coagulation GO:0050817 39 36 0,000 0,25937868 0,27696113 GO:0007596|blood coagulation, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,26554692 0,28338331 ! eye development GO:0001654 37 37 0,000 0,26554692 0,28321931 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,26554692 0,28305551 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,26554692 0,28289189 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,26554692 0,28272846 ! adaptive immune response GO:0002250 37 37 0,000 0,26554692 0,28256522 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,27166468 0,28890825 ! neurotransmitter transport GO:0006836 40 38 0,000 0,27166468 0,28874164 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,27166468 0,28857522 ! exocytosis GO:0006887 40 38 0,000 0,27166468 0,28840899 ! regulation of neurological system process GO:0031644 38 38 0,000 0,27166468 0,28824295 ! hemostasis GO:0007599 42 39 0,000 0,27773236 0,29451136 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,27773236 0,294342 ! activation of MAPK activity GO:0000187 39 39 0,000 0,27773236 0,29417284 ! response to unfolded protein GO:0006986 39 39 0,000 0,27773236 0,29400387 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,27773236 0,2938351 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,27773236 0,29366652 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,27773236 0,29349813 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,27773236 0,29332994 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,27773236 0,29316194 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,27773236 0,29299413 ! limb development GO:0060173 39 39 0,000 0,27773236 0,29282651 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! amine catabolic process GO:0009310 42 41 0,000 0,28971913 0,30529008 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,28971913 0,30511563 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,28971913 0,30494138 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,28971913 0,30476732 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,28971913 0,30459347 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,295639 0,31064007 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,295639 0,31046306 ! mRNA transport GO:0051028 44 44 0,000 0,30733369 0,32256036 ! vitamin metabolic process GO:0006766 44 44 0,000 0,30733369 0,32237678 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,30733369 0,3221934 ! amine biosynthetic process GO:0009309 46 45 0,000 0,31310929 0,32806164 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,31310929 0,32787524 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,31310929 0,32768905 ! protein processing GO:0016485 45 45 0,000 0,31310929 0,32750308 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,31883757 0,33330552 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,3245189 0,33905235 ! amine transport GO:0015837 47 47 0,000 0,3245189 0,33886025 ! calcium ion transport GO:0006816 48 48 0,000 0,33015368 0,34454883 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,33015368 0,34435384 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,33574227 0,34998473 ! divalent metal ion transport GO:0070838 49 49 0,000 0,33574227 0,34978689 ! response to bacterium GO:0009617 50 49 0,000 0,33574227 0,34958927 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,33574227 0,34939187 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,33574227 0,3491947 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,34128504 0,35475935 ! chromatin assembly GO:0031497 50 50 0,000 0,34128504 0,35455938 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,34128504 0,35435962 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,34128504 0,3541601 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,34678237 0,3596623 ! positive regulation of immune response GO:0050778 51 51 0,000 0,34678237 0,35946002 ! rRNA metabolic process GO:0016072 51 51 0,000 0,34678237 0,35925796 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,34678237 0,35905613 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,34678237 0,35885452 ! protein maturation GO:0051604 51 51 0,000 0,34678237 0,35865315 ! RNA localization GO:0006403 52 52 0,000 0,35223462 0,36408772 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,35223462 0,36388363 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,35223462 0,36367978 ! sodium ion transport GO:0006814 53 53 0,000 0,35764215 0,36905626 ! tRNA metabolic process GO:0006399 53 53 0,000 0,35764215 0,36884974 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,35764215 0,36864345 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,35764215 0,36843739 ! sulfur metabolic process GO:0006790 55 54 0,000 0,36300533 0,37375353 ! nucleosome organization GO:0034728 55 55 0,000 0,3683245 0,37901846 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,3683245 0,37880695 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,37360003 0,38401833 ! ATP metabolic process GO:0046034 57 57 0,000 0,37883227 0,38917942 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,37883227 0,38896261 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,38916827 0,39935251 ! potassium ion transport GO:0006813 60 60 0,000 0,39427271 0,40436539 ! cellular respiration GO:0045333 62 61 0,000 0,39933524 0,40932972 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,39933524 0,40910219 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,39933524 0,40887491 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,40435619 0,41378593 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,40435619 0,41355631 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,40435619 0,41332694 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,40933591 0,41818519 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,40933591 0,41795351 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,41427472 0,42276207 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,42403093 0,43247869 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,42403093 0,43223949 ! DNA packaging GO:0006323 66 66 0,000 0,42403093 0,43200055 ! polysaccharide metabolic process GO:0005976 69 66 0,000 0,42403093 0,43176188 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,42884899 0,43642666 ! muscle contraction GO:0006936 67 67 0,000 0,42884899 0,43618581 ! Ras protein signal transduction GO:0007265 69 67 0,000 0,42884899 0,43594522 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,43362744 0,44055974 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,43362744 0,44031701 ! sensory perception of sound GO:0007605 71 69 0,000 0,43836661 0,44488418 GO:0050954|sensory perception of mechanical stimulus, ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,44306682 0,44940679 GO:0016053|organic acid biosynthetic process, ! oxidative phosphorylation GO:0006119 71 71 0,000 0,44772837 0,45388525 ! secretion by cell GO:0032940 75 72 0,000 0,45235159 0,45831994 ! muscle system process GO:0003012 72 72 0,000 0,45235159 0,45806812 ! regulation of cytokine production GO:0001817 72 72 0,000 0,45235159 0,45781657 ! electron transport chain GO:0022900 75 74 0,000 0,46148424 0,46680322 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,46148424 0,46654715 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,46599429 0,4708484 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,46599429 0,4705904 ! regulation of immune response GO:0050776 78 78 0,000 0,47930295 0,48376525 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,48799379 0,49226741 ! lipid catabolic process GO:0016042 82 81 0,000 0,49228561 0,49632515 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,50076348 0,50459655 ! ncRNA processing GO:0034470 83 83 0,000 0,50076348 0,50432082 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,5049501 0,50825944 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,50910223 0,51215906 ! positive regulation of response to stimulus GO:0048584 86 85 0,000 0,50910223 0,51187965 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,51322013 0,51573866 GO:0006644|phospholipid metabolic process, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,5213544 0,52362733 ! chemotaxis GO:0006935 90 89 0,000 0,5253713 0,52737435 GO:0042330|taxis, ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,52935508 0,53108405 ! visual perception GO:0007601 93 92 0,000 0,53722433 0,53868577 GO:0050953|sensory perception of light stimulus, ! fatty acid metabolic process GO:0006631 93 92 0,000 0,53722433 0,53839284 ! positive regulation of immune system process GO:0002684 92 92 0,000 0,53722433 0,53810024 ! regulation of response to stress GO:0080134 97 94 0,000 0,54496428 0,54555631 ! cofactor metabolic process GO:0051186 95 94 0,000 0,54496428 0,54526013 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,56006458 0,56006458