pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6422-Schmidt-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 156 86 8,000 3,644E-08 8,38E-05 ! interphase GO:0051325 159 88 8,000 4,464E-08 5,134E-05 ! cartilage development GO:0051216 70 49 6,000 1,43E-07 1,096E-04 ! negative regulation of protein kinase activity GO:0006469 99 57 6,000 4,165E-07 2,395E-04 ! negative regulation of kinase activity GO:0033673 100 58 6,000 4,704E-07 2,164E-04 ! thymus development GO:0048538 15 9 3,000 5,388E-07 2,065E-04 ! negative regulation of transferase activity GO:0051348 105 61 6,000 6,687E-07 2,197E-04 ! regulation of epithelial cell proliferation GO:0050678 71 39 5,000 7,338E-07 2,11E-04 ! induction of apoptosis by intracellular signals GO:0008629 67 40 5,000 8,574E-07 2,191E-04 ! negative regulation of phosphorylation GO:0042326 41 23 4,000 1,056E-06 2,429E-04 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 4,000 1,325E-06 2,771E-04 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 5,000 1,334E-06 2,558E-04 ! chondrocyte differentiation GO:0002062 17 11 3,000 1,393E-06 2,465E-04 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 4,000 1,645E-06 2,703E-04 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 5,000 3,734E-06 5,726E-04 ! peptidyl-threonine phosphorylation GO:0018107 14 5 2,000 5,408E-06 7,774E-04 ! cell cycle arrest GO:0007050 150 86 6,000 6,938E-06 9,387E-04 ! positive regulation of protein ubiquitination GO:0031398 8 6 2,000 1,075E-05 1,374E-03 ! N-terminal protein amino acid acetylation GO:0006474 7 6 2,000 1,075E-05 1,301E-03 ! peptidyl-amino acid modification GO:0018193 147 93 6,000 1,166E-05 1,341E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 5,000 1,299E-05 1,423E-03 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 3,000 1,554E-05 1,625E-03 ! cell growth GO:0016049 61 39 4,000 1,625E-05 1,625E-03 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 2,000 1,87E-05 1,792E-03 ! peptidyl-threonine modification GO:0018210 18 7 2,000 1,87E-05 1,72E-03 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 3,000 2,37E-05 2,096E-03 ! positive regulation of phosphorylation GO:0042327 102 70 5,000 2,391E-05 2,037E-03 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 5,000 2,811E-05 2,309E-03 GO:0045937|positive regulation of phosphate metabolic process, ! vasculogenesis GO:0001570 33 22 3,000 2,878E-05 2,282E-03 ! glycolysis GO:0006096 53 44 4,000 2,966E-05 2,274E-03 ! induction of positive chemotaxis GO:0050930 14 8 2,000 2,974E-05 2,206E-03 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 2,000 2,974E-05 2,137E-03 ! regulation of gliogenesis GO:0014013 20 8 2,000 2,974E-05 2,073E-03 GO:0045685|regulation of glial cell differentiation, ! regulation of T cell differentiation in the thymus GO:0033081 12 8 2,000 2,974E-05 2,012E-03 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 2,000 2,974E-05 1,954E-03 ! regulation of telomere maintenance GO:0032204 10 8 2,000 2,974E-05 1,9E-03 ! regulation of embryonic development GO:0045995 16 8 2,000 2,974E-05 1,849E-03 ! insulin receptor signaling pathway GO:0008286 40 24 3,000 4,127E-05 2,498E-03 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 2,000 4,434E-05 2,615E-03 ! regulation of chromosome organization GO:0033044 35 25 3,000 4,882E-05 2,807E-03 ! ear development GO:0043583 72 50 4,000 5,561E-05 3,12E-03 ! positive regulation of cell migration GO:0030335 92 51 4,000 6,125E-05 3,354E-03 ! peptide or protein amino-terminal blocking GO:0018409 14 10 2,000 6,296E-05 3,367E-03 ! protein sumoylation GO:0016925 12 10 2,000 6,296E-05 3,291E-03 ! skeletal system morphogenesis GO:0048705 78 53 4,000 7,384E-05 3,774E-03 ! negative regulation of MAP kinase activity GO:0043407 54 28 3,000 7,751E-05 3,876E-03 ! glucose catabolic process GO:0006007 66 54 4,000 8,084E-05 3,956E-03 ! regulation of positive chemotaxis GO:0050926 17 11 2,000 8,604E-05 4,123E-03 GO:0050927|positive regulation of positive chemotaxis, ! focal adhesion formation GO:0048041 24 11 2,000 8,604E-05 4,039E-03 ! T cell homeostasis GO:0043029 20 11 2,000 8,604E-05 3,958E-03 ! negative regulation of glucose import GO:0046325 14 11 2,000 8,604E-05 3,88E-03 GO:0010829|negative regulation of glucose transport, ! positive regulation of cell motion GO:0051272 99 56 4,000 9,637E-05 4,262E-03 ! embryonic skeletal system morphogenesis GO:0048704 42 30 3,000 1,024E-04 4,445E-03 ! spindle organization GO:0007051 37 30 3,000 1,024E-04 4,363E-03 ! response to peptide hormone stimulus GO:0043434 84 57 4,000 1,049E-04 4,388E-03 ! histone acetylation GO:0016573 23 12 2,000 1,14E-04 4,683E-03 ! peptidyl-lysine modification GO:0018205 18 12 2,000 1,14E-04 4,601E-03 ! metanephros development GO:0001656 58 31 3,000 1,169E-04 4,634E-03 ! regulation of homeostatic process GO:0032844 105 60 4,000 1,342E-04 5,231E-03 ! urogenital system development GO:0001655 101 61 4,000 1,452E-04 5,567E-03 ! N-terminal protein amino acid modification GO:0031365 18 13 2,000 1,473E-04 5,556E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 2,000 1,473E-04 5,466E-03 ! cellular pigmentation GO:0033059 24 13 2,000 1,473E-04 5,379E-03 ! lymphocyte homeostasis GO:0002260 24 13 2,000 1,473E-04 5,295E-03 ! cellular response to insulin stimulus GO:0032869 52 34 3,000 1,69E-04 5,979E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 4,000 1,825E-04 6,359E-03 ! hexose catabolic process GO:0019320 82 64 4,000 1,825E-04 6,264E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 2,000 1,864E-04 6,305E-03 GO:0060675|ureteric bud morphogenesis, ! release of cytochrome c from mitochondria GO:0001836 23 14 2,000 1,864E-04 6,213E-03 ! regulation of protein ubiquitination GO:0031396 19 15 2,000 2,316E-04 7,61E-03 ! regulation of the force of heart contraction GO:0002026 21 15 2,000 2,316E-04 7,502E-03 ! peptidyl-serine phosphorylation GO:0018105 23 15 2,000 2,316E-04 7,398E-03 ! pigmentation GO:0043473 74 38 3,000 2,622E-04 8,26E-03 ! protein amino acid acetylation GO:0006473 28 16 2,000 2,833E-04 8,806E-03 ! neutrophil chemotaxis GO:0030593 21 16 2,000 2,833E-04 8,689E-03 ! inner ear receptor cell differentiation GO:0060113 30 16 2,000 2,833E-04 8,574E-03 ! monosaccharide catabolic process GO:0046365 91 71 4,000 2,975E-04 8,888E-03 ! inactivation of MAPK activity GO:0000188 27 17 2,000 3,42E-04 0,01008371 ! cell-substrate junction assembly GO:0007044 39 17 2,000 3,42E-04 9,956E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 3,42E-04 9,832E-03 ! peptidyl-serine modification GO:0018209 27 17 2,000 3,42E-04 9,71E-03 ! negative regulation of homeostatic process GO:0032845 28 17 2,000 3,42E-04 9,592E-03 ! regulation of T cell differentiation GO:0045580 59 41 3,000 3,529E-04 9,778E-03 ! branching morphogenesis of a tube GO:0048754 72 42 3,000 3,875E-04 0,01061054 ! embryonic skeletal system development GO:0048706 56 42 3,000 3,875E-04 0,01048571 ! mechanoreceptor differentiation GO:0042490 32 18 2,000 4,079E-04 0,01090877 ! apoptotic mitochondrial changes GO:0008637 29 18 2,000 4,079E-04 0,01078338 ! regulation of glucose import GO:0046324 21 18 2,000 4,079E-04 0,01066084 GO:0010827|regulation of glucose transport, ! response to insulin stimulus GO:0032868 63 43 3,000 4,245E-04 0,01097143 ! gland development GO:0048732 148 77 4,000 4,34E-04 0,01109222 ! positive regulation of protein modification process GO:0031401 107 78 4,000 4,607E-04 0,01164488 ! positive regulation of ossification GO:0045778 30 19 2,000 4,815E-04 0,01203646 ! response to alkaloid GO:0043279 32 19 2,000 4,815E-04 0,01190704 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 4,815E-04 0,01178037 ! sex determination GO:0007530 29 19 2,000 4,815E-04 0,01165636 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 2,000 4,815E-04 0,01153494 ! protein amino acid autophosphorylation GO:0046777 80 45 3,000 5,061E-04 0,01199968 ! alcohol catabolic process GO:0046164 104 80 4,000 5,178E-04 0,01215244 ! forebrain development GO:0030900 131 80 4,000 5,178E-04 0,01202969 ! regulation of ossification GO:0030278 71 46 3,000 5,508E-04 0,01266731 ! response to UV GO:0009411 75 46 3,000 5,508E-04 0,01254189 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 5,63E-04 0,01269543 ! positive regulation of locomotion GO:0040017 35 20 2,000 5,63E-04 0,01257217 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 30 20 2,000 5,63E-04 0,01245129 ! positive regulation of osteoblast differentiation GO:0045669 33 20 2,000 5,63E-04 0,0123327 ! ossification GO:0001503 134 82 4,000 5,8E-04 0,01258547 GO:0060348|bone development, ! regulation of muscle contraction GO:0006937 69 48 3,000 6,484E-04 0,01393765 ! regulation of lymphocyte differentiation GO:0045619 69 48 3,000 6,484E-04 0,0138086 ! positive regulation of bone remodeling GO:0046852 33 21 2,000 6,529E-04 0,01377681 GO:0034105|positive regulation of tissue remodeling, ! protein amino acid acylation GO:0043543 37 21 2,000 6,529E-04 0,01365157 ! regulation of chemotaxis GO:0050920 36 21 2,000 6,529E-04 0,01352858 ! activation of pro-apoptotic gene products GO:0008633 36 21 2,000 6,529E-04 0,01340779 ! cellular response to extracellular stimulus GO:0031668 32 21 2,000 6,529E-04 0,01328914 ! response to glucocorticoid stimulus GO:0051384 33 21 2,000 6,529E-04 0,01317257 ! embryonic camera-type eye development GO:0031076 8 5 1,000 6,629E-04 0,01325868 GO:0048596|embryonic camera-type eye morphogenesis, ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 6,629E-04 0,01314439 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 1,000 6,629E-04 0,01303204 ! positive regulation of glycolysis GO:0045821 11 5 1,000 6,629E-04 0,0129216 ! parathyroid gland development GO:0060017 8 5 1,000 6,629E-04 0,01281301 ! negative regulation of survival gene product expression GO:0008634 6 5 1,000 6,629E-04 0,01270624 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 1,000 6,629E-04 0,01260123 ! negative regulation of gliogenesis GO:0014014 16 5 1,000 6,629E-04 0,01249794 GO:0045686|negative regulation of glial cell differentiation, ! cranial nerve morphogenesis GO:0021602 6 5 1,000 6,629E-04 0,01239633 ! embryonic hemopoiesis GO:0035162 10 5 1,000 6,629E-04 0,01229636 ! homeostasis of number of cells within a tissue GO:0048873 9 5 1,000 6,629E-04 0,01219799 ! regulation of respiratory burst GO:0060263 8 5 1,000 6,629E-04 0,01210118 ! apical protein localization GO:0045176 6 5 1,000 6,629E-04 0,0120059 ! triglyceride catabolic process GO:0019433 6 5 1,000 6,629E-04 0,0119121 ! regulation of mitochondrial depolarization GO:0051900 9 5 1,000 6,629E-04 0,01181976 ! hemopoietic progenitor cell differentiation GO:0002244 10 5 1,000 6,629E-04 0,01172884 ! morphogenesis of a branching structure GO:0001763 86 49 3,000 7,016E-04 0,01231749 ! ureteric bud development GO:0001657 32 22 2,000 7,514E-04 0,0130934 ! regulation of behavior GO:0050795 38 22 2,000 7,514E-04 0,01299495 ! leukocyte homeostasis GO:0001776 33 22 2,000 7,514E-04 0,01289797 ! reproductive developmental process GO:0003006 127 89 4,000 8,427E-04 0,01435734 ! acetyl-CoA metabolic process GO:0006084 33 23 2,000 8,59E-04 0,01452674 ! cellular iron ion homeostasis GO:0006879 37 23 2,000 8,59E-04 0,0144207 ! response to corticosteroid stimulus GO:0031960 36 23 2,000 8,59E-04 0,0143162 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 2,000 8,59E-04 0,01421321 ! regulation of bone remodeling GO:0046850 90 53 3,000 9,452E-04 0,01552903 ! kidney development GO:0001822 90 53 3,000 9,452E-04 0,0154189 ! pyruvate metabolic process GO:0006090 29 24 2,000 9,758E-04 0,015805 ! regulation of oxidoreductase activity GO:0051341 39 24 2,000 9,758E-04 0,01569447 ! regulation of osteoblast differentiation GO:0045667 37 24 2,000 9,758E-04 0,01558548 ! cell fate commitment GO:0045165 141 92 4,000 9,79E-04 0,01552835 ! prostate gland development GO:0030850 9 6 1,000 9,89E-04 0,01558055 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 1,000 9,89E-04 0,01547456 ! regulation of protein export from nucleus GO:0046825 6 6 1,000 9,89E-04 0,01537 ! regulation of odontogenesis GO:0042481 8 6 1,000 9,89E-04 0,01526685 ! activation of MAPKKK activity GO:0000185 10 6 1,000 9,89E-04 0,01516507 ! pigment granule organization GO:0048753 11 6 1,000 9,89E-04 0,01506464 ! glutamate catabolic process GO:0006538 10 6 1,000 9,89E-04 0,01496553 ! cerebral cortex neuron differentiation GO:0021895 12 6 1,000 9,89E-04 0,01486772 ! glycerol ether catabolic process GO:0044269 8 6 1,000 9,89E-04 0,01477117 GO:0046464|acylglycerol catabolic process, ! male sex determination GO:0030238 9 6 1,000 9,89E-04 0,01467587 ! enucleate erythrocyte differentiation GO:0043353 9 6 1,000 9,89E-04 0,0145818 ! dendrite morphogenesis GO:0048813 9 6 1,000 9,89E-04 0,01448892 ! regulation of myeloid cell apoptosis GO:0033032 10 6 1,000 9,89E-04 0,01439722 ! myeloid dendritic cell activation GO:0001773 10 6 1,000 9,89E-04 0,01430667 GO:0043011|myeloid dendritic cell differentiation, ! regulation of tissue remodeling GO:0034103 91 54 3,000 1,014E-03 0,01458197 ! carbohydrate catabolic process GO:0016052 121 93 4,000 1,028E-03 0,01468313 ! male gonad development GO:0008584 33 25 2,000 1,102E-03 0,0156484 ! iron ion homeostasis GO:0055072 39 25 2,000 1,102E-03 0,0155524 ! peptidyl-tyrosine modification GO:0018212 37 25 2,000 1,102E-03 0,01545757 ! response to light stimulus GO:0009416 153 96 4,000 1,185E-03 0,01652212 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 2,000 1,238E-03 0,01715964 ! negative regulation of protein modification process GO:0031400 50 26 2,000 1,238E-03 0,01705689 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 1,377E-03 0,01885394 ! neutral lipid catabolic process GO:0046461 9 7 1,000 1,377E-03 0,01874238 ! regulation of lipid kinase activity GO:0043550 12 7 1,000 1,377E-03 0,01863213 ! regulation of smooth muscle cell migration GO:0014910 19 7 1,000 1,377E-03 0,01852317 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 1,000 1,377E-03 0,01841547 ! protein-cofactor linkage GO:0018065 13 7 1,000 1,377E-03 0,01830903 ! glycerolipid catabolic process GO:0046503 9 7 1,000 1,377E-03 0,0182038 ! regulation of pigmentation during development GO:0048070 15 7 1,000 1,377E-03 0,01809978 ! central nervous system neuron axonogenesis GO:0021955 14 7 1,000 1,377E-03 0,01799694 GO:0021952|central nervous system projection neuron axonogenesis, ! asymmetric protein localization GO:0008105 8 7 1,000 1,377E-03 0,01789526 ! organ growth GO:0035265 11 7 1,000 1,377E-03 0,01779473 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 1,000 1,377E-03 0,01769532 ! behavioral fear response GO:0001662 13 7 1,000 1,377E-03 0,01759701 GO:0002209|behavioral defense response, ! protein heterooligomerization GO:0051291 10 7 1,000 1,377E-03 0,01749979 ! response to UV-B GO:0010224 11 7 1,000 1,377E-03 0,01740363 ! B cell lineage commitment GO:0002326 17 7 1,000 1,377E-03 0,01730853 ! T cell lineage commitment GO:0002360 12 7 1,000 1,377E-03 0,01721446 ! neuroblast proliferation GO:0007405 13 7 1,000 1,377E-03 0,01712141 ! regulation of protein homodimerization activity GO:0043496 15 7 1,000 1,377E-03 0,01702936 ! trophectodermal cell differentiation GO:0001829 8 7 1,000 1,377E-03 0,0169383 ! negative regulation of telomere maintenance GO:0032205 9 7 1,000 1,377E-03 0,0168482 ! regulation of heart contraction GO:0008016 91 60 3,000 1,506E-03 0,01832275 ! response to organic cyclic substance GO:0014070 47 28 2,000 1,542E-03 0,01866413 ! cell junction assembly GO:0034329 56 28 2,000 1,542E-03 0,01856641 ! positive regulation of catabolic process GO:0009896 40 28 2,000 1,542E-03 0,01846971 ! meiosis GO:0007126 96 61 3,000 1,601E-03 0,01908072 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 3,000 1,601E-03 0,01898237 ! homeostasis of number of cells GO:0048872 84 61 3,000 1,601E-03 0,01888502 ! negative regulation of cell growth GO:0030308 106 62 3,000 1,701E-03 0,01995745 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 3,000 1,701E-03 0,01985615 ! meiotic cell cycle GO:0051321 97 62 3,000 1,701E-03 0,01975586 ! tissue homeostasis GO:0001894 42 29 2,000 1,709E-03 0,01975704 GO:0048871|multicellular organismal homeostasis, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 1,826E-03 0,02100242 ! axon extension GO:0048675 11 8 1,000 1,826E-03 0,02089793 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 1,826E-03 0,02079447 ! succinate metabolic process GO:0006105 14 8 1,000 1,826E-03 0,02069203 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 1,000 1,826E-03 0,0205906 ! middle ear morphogenesis GO:0042474 9 8 1,000 1,826E-03 0,02049016 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 1,826E-03 0,02039069 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 1,000 1,826E-03 0,02029219 ! L-phenylalanine metabolic process GO:0006558 8 8 1,000 1,826E-03 0,02019463 GO:0006559|L-phenylalanine catabolic process, ! melanin metabolic process GO:0006582 12 8 1,000 1,826E-03 0,02009801 ! embryonic eye morphogenesis GO:0048048 12 8 1,000 1,826E-03 0,0200023 ! regulation of smoothened signaling pathway GO:0008589 13 8 1,000 1,826E-03 0,0199075 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 1,000 1,826E-03 0,0198136 ! regulation of mitochondrial membrane potential GO:0051881 11 8 1,000 1,826E-03 0,01972058 ! induction of an organ GO:0001759 11 8 1,000 1,826E-03 0,01962843 ! S phase GO:0051320 8 8 1,000 1,826E-03 0,01953713 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage differentiation GO:0045649 14 8 1,000 1,826E-03 0,01944668 ! hindbrain development GO:0030902 45 30 2,000 1,888E-03 0,02001071 ! response to heat GO:0009408 41 30 2,000 1,888E-03 0,01991891 ! negative regulation of cell size GO:0045792 108 64 3,000 1,913E-03 0,02008755 ! reproductive structure development GO:0048608 90 65 3,000 2,025E-03 0,02117285 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 3,000 2,025E-03 0,02107705 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 3,000 2,025E-03 0,02098211 ! leukocyte chemotaxis GO:0030595 43 31 2,000 2,078E-03 0,02142948 GO:0060326|cell chemotaxis, ! cell-substrate adhesion GO:0031589 121 66 3,000 2,142E-03 0,02199654 ! meiosis I GO:0007127 52 32 2,000 2,279E-03 0,02329581 ! regulation of developmental growth GO:0048638 13 9 1,000 2,335E-03 0,02376763 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 2,335E-03 0,02366293 ! regulation of epithelial cell differentiation GO:0030856 13 9 1,000 2,335E-03 0,02355915 ! regulation of glycolysis GO:0006110 15 9 1,000 2,335E-03 0,02345627 ! T cell selection GO:0045058 18 9 1,000 2,335E-03 0,02335428 ! telomere maintenance via telomerase GO:0007004 12 9 1,000 2,335E-03 0,02325318 GO:0010833|telomere maintenance via telomere lengthening, ! motor axon guidance GO:0008045 14 9 1,000 2,335E-03 0,02315295 ! alpha-beta T cell differentiation GO:0046632 14 9 1,000 2,335E-03 0,02305358 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 1,000 2,335E-03 0,02295506 ! oocyte differentiation GO:0009994 12 9 1,000 2,335E-03 0,02285738 GO:0048599|oocyte development, ! spleen development GO:0048536 15 9 1,000 2,335E-03 0,02276053 ! blastocyst formation GO:0001825 12 9 1,000 2,335E-03 0,02266449 ! embryonic placenta development GO:0001892 12 9 1,000 2,335E-03 0,02256927 ! sequestering of metal ion GO:0051238 11 9 1,000 2,335E-03 0,02247483 ! response to nicotine GO:0035094 16 9 1,000 2,335E-03 0,02238119 ! localization within membrane GO:0051668 15 9 1,000 2,335E-03 0,02228832 ! cell junction organization GO:0034330 63 33 2,000 2,492E-03 0,02368266 ! positive regulation of cell development GO:0010720 54 33 2,000 2,492E-03 0,0235852 ! positive regulation of ligase activity GO:0051351 99 69 3,000 2,521E-03 0,02376622 ! development of primary male sexual characteristics GO:0046546 44 34 2,000 2,717E-03 0,02550297 ! embryonic organ development GO:0048568 45 34 2,000 2,717E-03 0,0253993 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 3,000 2,798E-03 0,02605512 ! regulation of B cell proliferation GO:0030888 15 10 1,000 2,904E-03 0,02692805 ! hair follicle morphogenesis GO:0031069 17 10 1,000 2,904E-03 0,02681991 ! hippocampus development GO:0021766 19 10 1,000 2,904E-03 0,02671263 ! B cell proliferation GO:0042100 14 10 1,000 2,904E-03 0,0266062 ! neurotransmitter biosynthetic process GO:0042136 14 10 1,000 2,904E-03 0,02650062 ! fear response GO:0042596 16 10 1,000 2,904E-03 0,02639588 ! negative regulation of ossification GO:0030279 19 10 1,000 2,904E-03 0,02629195 ! alpha-beta T cell activation GO:0046631 16 10 1,000 2,904E-03 0,02618885 ! RNA-dependent DNA replication GO:0006278 13 10 1,000 2,904E-03 0,02608655 ! cranial nerve development GO:0021545 12 10 1,000 2,904E-03 0,02598504 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 2,904E-03 0,02588433 GO:0043470|regulation of carbohydrate catabolic process, ! cardiac cell differentiation GO:0035051 16 10 1,000 2,904E-03 0,02578439 ! developmental induction GO:0031128 13 10 1,000 2,904E-03 0,02568522 GO:0045168|cell-cell signaling involved in cell fate specification, ! negative regulation of transport GO:0051051 116 73 3,000 3,095E-03 0,02727421 ! tube morphogenesis GO:0035239 118 73 3,000 3,095E-03 0,02717011 ! response to reactive oxygen species GO:0000302 55 36 2,000 3,203E-03 0,02800904 ! cellular response to hormone stimulus GO:0032870 109 74 3,000 3,251E-03 0,0283254 ! negative regulation of growth GO:0045926 123 75 3,000 3,413E-03 0,02962044 ! response to nutrient GO:0007584 104 75 3,000 3,413E-03 0,02950908 ! regulation of ligase activity GO:0051340 114 75 3,000 3,413E-03 0,02939856 ! virus-host interaction GO:0019048 17 11 1,000 3,53E-03 0,03029184 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 3,53E-03 0,03017923 ! detection of mechanical stimulus GO:0050982 15 11 1,000 3,53E-03 0,03006746 ! regulation of mRNA processing GO:0050684 18 11 1,000 3,53E-03 0,02995651 ! mitotic spindle organization GO:0007052 15 11 1,000 3,53E-03 0,02984637 ! aromatic amino acid family catabolic process GO:0009074 13 11 1,000 3,53E-03 0,02973705 ! digestive tract morphogenesis GO:0048546 15 11 1,000 3,53E-03 0,02962852 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! negative regulation of mast cell proliferation GO:0070667 17 11 1,000 3,53E-03 0,02952078 GO:0042130|negative regulation of T cell proliferation, ! mesenchymal cell development GO:0014031 64 38 2,000 3,739E-03 0,0311586 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! sex differentiation GO:0007548 105 77 3,000 3,752E-03 0,03115426 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 2,000 4,026E-03 0,03331218 ! male sex differentiation GO:0046661 53 39 2,000 4,026E-03 0,03319278 ! JNK cascade GO:0007254 54 39 2,000 4,026E-03 0,03307424 ! synapse organization GO:0050808 55 39 2,000 4,026E-03 0,03295654 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 4,213E-03 0,03435958 ! palate development GO:0060021 15 12 1,000 4,213E-03 0,03423817 ! regulation of skeletal muscle fiber development GO:0048742 20 12 1,000 4,213E-03 0,03411761 ! tyrosine metabolic process GO:0006570 14 12 1,000 4,213E-03 0,0339979 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 4,213E-03 0,03387903 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! autonomic nervous system development GO:0048483 23 12 1,000 4,213E-03 0,03376098 ! gland morphogenesis GO:0022612 23 12 1,000 4,213E-03 0,03364376 ! response to gamma radiation GO:0010332 20 12 1,000 4,213E-03 0,03352734 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 2,000 4,327E-03 0,03431689 ! positive regulation of response to external stimulus GO:0032103 65 40 2,000 4,327E-03 0,03419897 ! detection of stimulus involved in sensory perception GO:0050906 50 40 2,000 4,327E-03 0,03408185 ! inner ear development GO:0048839 57 40 2,000 4,327E-03 0,03396553 ! T cell differentiation GO:0030217 65 40 2,000 4,327E-03 0,03385 ! regulation of myeloid cell differentiation GO:0045637 69 40 2,000 4,327E-03 0,03373525 ! JAK-STAT cascade GO:0007259 53 40 2,000 4,327E-03 0,03362128 ! regulation of cell adhesion GO:0030155 159 83 3,000 4,906E-03 0,03798921 ! glutamate metabolic process GO:0006536 18 13 1,000 4,952E-03 0,03821978 ! negative regulation of mitotic cell cycle GO:0045930 23 13 1,000 4,952E-03 0,03809195 ! bone mineralization GO:0030282 15 13 1,000 4,952E-03 0,03796498 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 4,952E-03 0,03783885 ! positive regulation of bone mineralization GO:0030501 19 13 1,000 4,952E-03 0,03771355 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 1,000 4,952E-03 0,03758909 ! microtubule cytoskeleton organization GO:0000226 120 84 3,000 5,118E-03 0,03872517 ! regulation of gene-specific transcription GO:0032583 69 43 2,000 5,309E-03 0,0400318 ! leukocyte migration GO:0050900 60 43 2,000 5,309E-03 0,03990097 ! epithelial tube morphogenesis GO:0060562 65 43 2,000 5,309E-03 0,039771 ! regulation of DNA metabolic process GO:0051052 135 85 3,000 5,337E-03 0,03985764 ! positive regulation of MAP kinase activity GO:0043406 121 85 3,000 5,337E-03 0,03972865 ! anterior/posterior pattern formation GO:0009952 124 85 3,000 5,337E-03 0,0396005 ! regulation of membrane potential GO:0042391 128 85 3,000 5,337E-03 0,03947316 ! regulation of action potential GO:0001508 71 44 2,000 5,663E-03 0,04174678 ! induction of apoptosis by extracellular signals GO:0008624 74 44 2,000 5,663E-03 0,04161341 ! regulation of inflammatory response GO:0050727 60 44 2,000 5,663E-03 0,04148088 ! detection of abiotic stimulus GO:0009582 58 44 2,000 5,663E-03 0,04134919 ! regulation of mast cell proliferation GO:0070666 64 44 2,000 5,663E-03 0,04121834 ! regulation of skeletal muscle tissue development GO:0048641 22 14 1,000 5,746E-03 0,04169176 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 5,746E-03 0,04156065 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 5,746E-03 0,04143037 ! heterophilic cell adhesion GO:0007157 29 14 1,000 5,746E-03 0,0413009 ! limbic system development GO:0021761 25 14 1,000 5,746E-03 0,04117224 ! activation of MAPKK activity GO:0000186 21 14 1,000 5,746E-03 0,04104437 ! epidermis morphogenesis GO:0048730 29 14 1,000 5,746E-03 0,0409173 ! G1/S transition checkpoint GO:0031575 33 14 1,000 5,746E-03 0,04079101 ! positive regulation of biomineral formation GO:0070169 20 14 1,000 5,746E-03 0,0406655 ! T cell differentiation in the thymus GO:0033077 27 14 1,000 5,746E-03 0,04054076 ! regulation of erythrocyte differentiation GO:0045646 27 14 1,000 5,746E-03 0,04041678 ! epithelial to mesenchymal transition GO:0001837 22 14 1,000 5,746E-03 0,04029356 ! positive regulation of cell cycle GO:0045787 77 45 2,000 6,031E-03 0,04216478 ! positive regulation of defense response GO:0031349 59 45 2,000 6,031E-03 0,04203701 ! anatomical structure homeostasis GO:0060249 136 88 3,000 6,032E-03 0,04191335 ! regulation of neurogenesis GO:0050767 153 89 3,000 6,276E-03 0,04347883 ! regulation of T cell activation GO:0050863 128 89 3,000 6,276E-03 0,04334826 ! histone modification GO:0016570 68 46 2,000 6,414E-03 0,04416666 ! leukocyte differentiation GO:0002521 143 90 3,000 6,527E-03 0,04481055 ! protein modification by small protein conjugation GO:0032446 140 90 3,000 6,527E-03 0,04467719 ! metencephalon development GO:0022037 19 15 1,000 6,595E-03 0,04500775 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 6,595E-03 0,04487459 ! lipid phosphorylation GO:0046834 23 15 1,000 6,595E-03 0,04474222 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 1,000 6,595E-03 0,04461063 ! regulation of muscle cell differentiation GO:0051147 24 15 1,000 6,595E-03 0,0444798 ! regulation of survival gene product expression GO:0045884 20 15 1,000 6,595E-03 0,04434975 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 1,000 6,595E-03 0,04422045 ! positive regulation of oxidoreductase activity GO:0051353 21 15 1,000 6,595E-03 0,0440919 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 6,595E-03 0,0439641 ! biomineral formation GO:0031214 18 15 1,000 6,595E-03 0,04383703 ! negative regulation of leukocyte proliferation GO:0070664 25 15 1,000 6,595E-03 0,0437107 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 27 15 1,000 6,595E-03 0,04358509 ! covalent chromatin modification GO:0016569 75 47 2,000 6,81E-03 0,04488154 ! regulation of leukocyte proliferation GO:0070663 71 47 2,000 6,81E-03 0,04475331 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! response to temperature stimulus GO:0009266 62 48 2,000 7,221E-03 0,0473176 ! heart morphogenesis GO:0003007 65 48 2,000 7,221E-03 0,04718318 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 2,000 7,221E-03 0,04704951 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 7,496E-03 0,0487043 ! patterning of blood vessels GO:0001569 24 16 1,000 7,496E-03 0,0485671 ! regulation of protein binding GO:0043393 27 16 1,000 7,496E-03 0,04843068 ! oogenesis GO:0048477 23 16 1,000 7,496E-03 0,04829502 ! G1 phase GO:0051318 27 16 1,000 7,496E-03 0,04816012 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 7,496E-03 0,04802596 ! nerve development GO:0021675 18 16 1,000 7,496E-03 0,04789256 ! response to oxidative stress GO:0006979 141 94 3,000 7,596E-03 0,04839398 ! germ cell development GO:0007281 68 49 2,000 7,646E-03 0,04858123 ! positive regulation of growth GO:0045927 67 50 2,000 8,086E-03 0,05123334 ! in utero embryonic development GO:0001701 147 96 3,000 8,171E-03 0,05162988 ! protein modification by small protein conjugation or removal GO:0070647 148 96 3,000 8,171E-03 0,05148843 ! signal complex assembly GO:0007172 29 17 1,000 8,45E-03 0,0531019 ! regulation of viral genome replication GO:0045069 24 17 1,000 8,45E-03 0,0529572 ! regulation of striated muscle contraction GO:0006942 20 17 1,000 8,45E-03 0,0528133 ! actin filament bundle formation GO:0051017 26 17 1,000 8,45E-03 0,05267017 ! neuromuscular junction development GO:0007528 23 17 1,000 8,45E-03 0,05252782 ! negative regulation of intracellular transport GO:0032387 29 17 1,000 8,45E-03 0,05238624 ! synaptogenesis GO:0007416 24 17 1,000 8,45E-03 0,05224541 ! aromatic compound catabolic process GO:0019439 22 17 1,000 8,45E-03 0,05210534 ! Ras protein signal transduction GO:0007265 162 100 3,000 9,406E-03 0,05784206 ! positive regulation of DNA replication GO:0045740 29 18 1,000 9,455E-03 0,05799316 ! central nervous system neuron development GO:0021954 30 18 1,000 9,455E-03 0,05783893 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 1,000 9,455E-03 0,05768551 ! somitogenesis GO:0001756 24 18 1,000 9,455E-03 0,0575329 ! cellular response to nutrient levels GO:0031669 27 18 1,000 9,455E-03 0,0573811 ! negative regulation of neuron differentiation GO:0045665 24 18 1,000 9,455E-03 0,05723009 ! gut development GO:0048565 26 18 1,000 9,455E-03 0,05707988 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 1,000 9,455E-03 0,05693046 ! negative regulation of T cell activation GO:0050868 25 18 1,000 9,455E-03 0,05678182 ! regulation of mitosis GO:0007088 84 54 2,000 9,992E-03 0,05984724 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 66 54 2,000 9,992E-03 0,05969179 ! cellular amino acid catabolic process GO:0009063 74 54 2,000 9,992E-03 0,05953715 ! positive regulation of protein catabolic process GO:0045732 23 19 1,000 0,01051117 0,06246946 ! positive regulation of fibroblast proliferation GO:0048146 27 19 1,000 0,01051117 0,06230846 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 0,01051117 0,06214828 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regeneration GO:0031099 32 19 1,000 0,01051117 0,06198893 ! cellular response to reactive oxygen species GO:0034614 27 19 1,000 0,01051117 0,06183039 ! cell structure disassembly during apoptosis GO:0006921 24 19 1,000 0,01051117 0,06167266 ! apoptotic nuclear changes GO:0030262 24 19 1,000 0,01051117 0,06151573 ! renal system process GO:0003014 35 19 1,000 0,01051117 0,0613596 ! aromatic amino acid family metabolic process GO:0009072 24 19 1,000 0,01051117 0,06120426 ! embryonic organ morphogenesis GO:0048562 23 19 1,000 0,01051117 0,0610497 ! negative regulation of response to stimulus GO:0048585 80 56 2,000 0,01103444 0,0639275 ! multicellular organism reproduction GO:0032504 83 57 2,000 0,01157841 0,06691039 GO:0048609|reproductive process in a multicellular organism, ! camera-type eye development GO:0043010 88 57 2,000 0,01157841 0,06674269 ! gonad development GO:0008406 79 57 2,000 0,01157841 0,06657584 ! response to ethanol GO:0045471 37 20 1,000 0,01161652 0,06662839 ! multicellular organismal response to stress GO:0033555 32 20 1,000 0,01161652 0,06646265 ! central nervous system neuron differentiation GO:0021953 33 20 1,000 0,01161652 0,06629773 ! neurotransmitter metabolic process GO:0042133 30 20 1,000 0,01161652 0,06613363 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 1,000 0,01161652 0,06597034 ! pallium development GO:0021543 38 20 1,000 0,01161652 0,06580785 ! positive regulation of B cell activation GO:0050871 31 20 1,000 0,01161652 0,06564616 ! camera-type eye morphogenesis GO:0048593 34 20 1,000 0,01161652 0,06548526 ! lung development GO:0030324 94 59 2,000 0,01271205 0,07148588 ! actin filament organization GO:0007015 95 59 2,000 0,01271205 0,07131152 ! myeloid cell differentiation GO:0030099 85 59 2,000 0,01271205 0,07113802 ! myeloid leukocyte differentiation GO:0002573 33 21 1,000 0,01277058 0,07129208 ! gluconeogenesis GO:0006094 25 21 1,000 0,01277058 0,07111946 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 1,000 0,01277058 0,07094767 ! phototransduction GO:0007602 25 21 1,000 0,01277058 0,07077671 ! dendrite development GO:0016358 35 21 1,000 0,01277058 0,07060657 ! ovarian follicle development GO:0001541 30 21 1,000 0,01277058 0,07043725 ! cell aging GO:0007569 32 21 1,000 0,01277058 0,07026874 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 1,000 0,01277058 0,07010104 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 1,000 0,01277058 0,06993413 ! regulation of bone mineralization GO:0030500 29 21 1,000 0,01277058 0,06976802 ! response to cytokine stimulus GO:0034097 47 21 1,000 0,01277058 0,06960269 ! glutamine family amino acid catabolic process GO:0009065 30 21 1,000 0,01277058 0,06943814 ! acetyl-CoA catabolic process GO:0046356 31 21 1,000 0,01277058 0,06927437 GO:0006099|tricarboxylic acid cycle, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 2,000 0,01390708 0,07526182 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 0,01397249 0,07543835 ! molting cycle process GO:0022404 40 22 1,000 0,01397249 0,07526168 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 1,000 0,01397249 0,07508583 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 1,000 0,01397249 0,07491081 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 0,01397249 0,07473659 GO:0010810|regulation of cell-substrate adhesion, ! coenzyme catabolic process GO:0009109 33 22 1,000 0,01397249 0,07456319 ! blastocyst development GO:0001824 37 22 1,000 0,01397249 0,07439059 ! protein tetramerization GO:0051262 39 22 1,000 0,01397249 0,07421879 ! amine catabolic process GO:0009310 90 62 2,000 0,01452774 0,07699032 ! respiratory tube development GO:0030323 99 62 2,000 0,01452774 0,07681333 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 0,0152214 0,08029638 ! myelination GO:0042552 35 23 1,000 0,0152214 0,08011263 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 0,0152214 0,07992973 ! osteoblast differentiation GO:0001649 40 23 1,000 0,0152214 0,07974766 ! regulation of viral reproduction GO:0050792 32 23 1,000 0,0152214 0,07956641 ! interaction with host GO:0051701 37 23 1,000 0,0152214 0,07938599 ! lymphocyte proliferation GO:0046651 36 23 1,000 0,0152214 0,07920638 ! regulation of biomineral formation GO:0070167 31 23 1,000 0,0152214 0,07902759 ! cellular response to oxidative stress GO:0034599 33 23 1,000 0,0152214 0,0788496 ! telomere organization GO:0032200 32 23 1,000 0,0152214 0,07867241 GO:0000723|telomere maintenance, ! cell cycle checkpoint GO:0000075 108 64 2,000 0,0158156 0,08156025 ! respiratory system development GO:0060541 100 64 2,000 0,0158156 0,08137779 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 0,01651646 0,08479431 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 1,000 0,01651646 0,08460546 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! mitochondrial membrane organization GO:0007006 39 24 1,000 0,01651646 0,08441744 ! response to toxin GO:0009636 38 24 1,000 0,01651646 0,08423027 ! negative regulation of cell development GO:0010721 56 24 1,000 0,01651646 0,08404392 GO:0050768|negative regulation of neurogenesis, ! regulation of alpha-beta T cell activation GO:0046634 35 24 1,000 0,01651646 0,08385839 ! glutathione metabolic process GO:0006749 29 24 1,000 0,01651646 0,08367368 ! regulation of JUN kinase activity GO:0043506 34 24 1,000 0,01651646 0,08348978 ! regulation of Rho protein signal transduction GO:0035023 111 66 2,000 0,01716576 0,08658167 ! calcium-dependent cell-cell adhesion GO:0016339 30 25 1,000 0,01785683 0,08987025 ! detection of light stimulus GO:0009583 30 25 1,000 0,01785683 0,08967402 ! positive regulation of nuclear division GO:0051785 39 25 1,000 0,01785683 0,08947865 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 1,000 0,01785683 0,08928414 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 0,01785683 0,08909046 ! regulation of neuron differentiation GO:0045664 107 67 2,000 0,01786428 0,08893474 ! learning or memory GO:0007611 123 68 2,000 0,01857847 0,09229046 ! development of primary sexual characteristics GO:0045137 92 68 2,000 0,01857847 0,09209156 ! post-embryonic development GO:0009791 42 26 1,000 0,01924169 0,09517395 ! activation of protein kinase activity GO:0032147 102 69 2,000 0,01930834 0,09529869 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 2,000 0,02005392 0,09876661 ! eye development GO:0001654 111 70 2,000 0,02005392 0,09855557 ! response to metal ion GO:0010038 103 70 2,000 0,02005392 0,09834543 ! regulation of catabolic process GO:0009894 106 70 2,000 0,02005392 0,09813618 ! response to ionizing radiation GO:0010212 47 27 1,000 0,02067023 0,10093743 ! cofactor catabolic process GO:0051187 45 27 1,000 0,02067023 0,10072358 ! negative regulation of leukocyte activation GO:0002695 39 27 1,000 0,02067023 0,10051063 ! negative regulation of neuron apoptosis GO:0043524 42 27 1,000 0,02067023 0,10029859 ! negative regulation of protein transport GO:0051224 49 27 1,000 0,02067023 0,10008743 ! phosphoinositide-mediated signaling GO:0048015 109 71 2,000 0,0208152 0,10057766 ! lymphocyte differentiation GO:0030098 113 71 2,000 0,0208152 0,1003668 ! response to hypoxia GO:0001666 132 72 2,000 0,02159221 0,10389557 ! negative regulation of organelle organization GO:0010639 115 72 2,000 0,02159221 0,10367867 ! triglyceride metabolic process GO:0006641 34 28 1,000 0,02214165 0,10609539 ! erythrocyte differentiation GO:0030218 38 28 1,000 0,02214165 0,10587482 ! positive regulation of T cell differentiation GO:0045582 39 28 1,000 0,02214165 0,10565516 ! positive regulation of multicellular organism growth GO:0040018 38 28 1,000 0,02214165 0,10543641 ! ensheathment of neurons GO:0007272 43 28 1,000 0,02214165 0,10521857 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 1,000 0,02214165 0,10500162 ! myeloid leukocyte activation GO:0002274 39 28 1,000 0,02214165 0,10478557 ! placenta development GO:0001890 37 28 1,000 0,02214165 0,1045704 ! regulation of B cell activation GO:0050864 42 28 1,000 0,02214165 0,10435612 ! mitochondrion organization GO:0007005 104 73 2,000 0,02238495 0,10528707 ! response to steroid hormone stimulus GO:0048545 114 73 2,000 0,02238495 0,1050722 ! response to oxygen levels GO:0070482 137 74 2,000 0,02319341 0,10864531 ! positive regulation of lymphocyte activation GO:0051251 108 74 2,000 0,02319341 0,10842449 ! response to hydrogen peroxide GO:0042542 42 29 1,000 0,02365515 0,11035869 ! ovulation cycle process GO:0022602 41 29 1,000 0,02365515 0,11013529 ! mismatch repair GO:0006298 34 29 1,000 0,02365515 0,1099128 ! telencephalon development GO:0021537 52 29 1,000 0,02365515 0,1096912 ! hexose biosynthetic process GO:0019319 35 29 1,000 0,02365515 0,10947049 ! eye morphogenesis GO:0048592 51 29 1,000 0,02365515 0,10925067 ! response to inorganic substance GO:0010035 115 75 2,000 0,0240176 0,11070239 ! positive regulation of neurogenesis GO:0050769 45 30 1,000 0,02520994 0,11596574 ! ovulation cycle GO:0042698 43 30 1,000 0,02520994 0,11573427 ! negative regulation of cell activation GO:0050866 44 30 1,000 0,02520994 0,11550373 ! nitrogen compound catabolic process GO:0044270 114 78 2,000 0,02658447 0,12155922 ! mammary gland development GO:0030879 57 31 1,000 0,02680527 0,12232563 ! odontogenesis GO:0042476 50 31 1,000 0,02680527 0,1220834 ! segmentation GO:0035282 41 31 1,000 0,02680527 0,12184213 ! regulation of striated muscle tissue development GO:0016202 47 31 1,000 0,02680527 0,12160181 ! response to mechanical stimulus GO:0009612 43 31 1,000 0,02680527 0,12136244 ! cell fate specification GO:0001708 37 31 1,000 0,02680527 0,12112401 ! T cell activation GO:0042110 134 79 2,000 0,02747149 0,12389101 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 2,000 0,02837416 0,1277115 GO:0010498|proteasomal protein catabolic process, ! regulation of muscle development GO:0048634 48 32 1,000 0,02844036 0,12775942 ! mitotic sister chromatid segregation GO:0000070 45 32 1,000 0,02844036 0,12751038 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 0,02844036 0,1272623 ! neutral lipid metabolic process GO:0006638 41 32 1,000 0,02844036 0,12701519 GO:0006639|acylglycerol metabolic process, ! peripheral nervous system development GO:0007422 53 32 1,000 0,02844036 0,12676904 ! regulation of protein stability GO:0031647 48 32 1,000 0,02844036 0,12652384 ! calcium-mediated signaling GO:0019722 50 32 1,000 0,02844036 0,12627958 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 1,000 0,02844036 0,12603627 ! monosaccharide biosynthetic process GO:0046364 38 32 1,000 0,02844036 0,12579389 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 0,02844036 0,12555244 ! regulation of cell cycle process GO:0010564 122 81 2,000 0,02929248 0,1290665 ! response to protein stimulus GO:0051789 111 81 2,000 0,02929248 0,12881972 ! positive regulation of cell activation GO:0050867 120 81 2,000 0,02929248 0,12857388 GO:0002696|positive regulation of leukocyte activation, ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 0,03011446 0,13193 ! sister chromatid segregation GO:0000819 46 33 1,000 0,03011446 0,13167918 ! ear morphogenesis GO:0042471 42 33 1,000 0,03011446 0,13142932 ! carbohydrate homeostasis GO:0033500 39 33 1,000 0,03011446 0,1311804 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 1,000 0,03011446 0,13093242 ! female gonad development GO:0008585 49 33 1,000 0,03011446 0,13068538 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 0,03011446 0,13043927 ! cytokinesis GO:0000910 52 33 1,000 0,03011446 0,13019408 ! detection of stimulus GO:0051606 108 82 2,000 0,03022643 0,13043298 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 0,03182682 0,13708181 ! glycerol ether metabolic process GO:0006662 44 34 1,000 0,03182682 0,13682559 ! erythrocyte homeostasis GO:0034101 45 34 1,000 0,03182682 0,13657032 ! neuron migration GO:0001764 46 34 1,000 0,03182682 0,13631599 ! female gamete generation GO:0007292 43 34 1,000 0,03182682 0,13606262 ! aerobic respiration GO:0009060 47 34 1,000 0,03182682 0,13581018 ! dorsal/ventral pattern formation GO:0009953 44 34 1,000 0,03182682 0,13555868 ! regulation of defense response GO:0031347 117 84 2,000 0,03214105 0,13664403 ! regulation of protein localization GO:0032880 132 85 2,000 0,03312167 0,14055321 ! regulation of intracellular protein transport GO:0033157 59 35 1,000 0,03357672 0,14222182 ! regulation of action potential in neuron GO:0019228 54 35 1,000 0,03357672 0,14196039 ! pigment metabolic process GO:0042440 61 35 1,000 0,03357672 0,14169991 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,03357672 0,14144039 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! skeletal muscle tissue development GO:0007519 123 87 2,000 0,03512934 0,1477102 GO:0060538|skeletal muscle organ development, ! female pregnancy GO:0007565 130 87 2,000 0,03512934 0,14744066 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,03536342 0,14815276 GO:0090047|positive regulation of transcription regulator activity, ! organic ether metabolic process GO:0018904 46 36 1,000 0,03536342 0,14788339 ! development of primary female sexual characteristics GO:0046545 52 36 1,000 0,03536342 0,147615 GO:0046660|female sex differentiation, ! carboxylic acid catabolic process GO:0046395 122 88 2,000 0,03615631 0,15065129 GO:0016054|organic acid catabolic process, ! learning GO:0007612 67 37 1,000 0,03718621 0,15466237 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 1,000 0,03904439 0,16209765 ! striated muscle cell differentiation GO:0051146 54 38 1,000 0,03904439 0,16180558 ! alcohol biosynthetic process GO:0046165 45 38 1,000 0,03904439 0,16151456 ! regulation of T cell proliferation GO:0042129 58 38 1,000 0,03904439 0,16122459 ! maintenance of location in cell GO:0051651 69 38 1,000 0,03904439 0,16093566 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,04051686 0,1667062 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,04051686 0,16640851 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,04051686 0,16611188 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,04051686 0,16581631 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,04051686 0,16552179 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,04051686 0,16522831 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,04051686 0,16493587 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,04051686 0,16464446 ! sleep GO:0030431 11 5 0,000 0,04051686 0,16435409 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,04051686 0,16406473 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,04051686 0,16377639 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,04051686 0,16348906 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,04051686 0,16320274 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,04051686 0,16291742 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,04051686 0,1626331 ! tongue development GO:0043586 6 5 0,000 0,04051686 0,16234977 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,04051686 0,16206742 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,04051686 0,16178605 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,04051686 0,16150566 ! cobalt ion transport GO:0006824 9 5 0,000 0,04051686 0,16122624 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,04051686 0,16094778 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,04051686 0,16067029 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,04051686 0,16039375 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,04051686 0,16011816 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,04051686 0,15984351 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,04051686 0,15956981 ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,04051686 0,15929704 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,04051686 0,1590252 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,04051686 0,15875429 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,04051686 0,1584843 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,04051686 0,15821522 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,04051686 0,15794706 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,04051686 0,15767981 ! malate metabolic process GO:0006108 7 5 0,000 0,04051686 0,15741346 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,04051686 0,157148 ! behavioral response to pain GO:0048266 7 5 0,000 0,04051686 0,15688345 ! clathrin coat assembly GO:0048268 11 5 0,000 0,04051686 0,15661978 ! phototransduction, visible light GO:0007603 6 5 0,000 0,04051686 0,15635699 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,04051686 0,15609509 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,04051686 0,15583406 ! mating behavior GO:0007617 6 5 0,000 0,04051686 0,1555739 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,04051686 0,15531461 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,04051686 0,15505618 ! rhythmic behavior GO:0007622 12 5 0,000 0,04051686 0,15479862 ! copulation GO:0007620 7 5 0,000 0,04051686 0,1545419 ! glial cell fate commitment GO:0021781 12 5 0,000 0,04051686 0,15428604 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,04051686 0,15403102 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,04051686 0,15377684 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,04051686 0,1535235 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,04051686 0,153271 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,04051686 0,15301932 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,04051686 0,15276847 ! response to protozoan GO:0001562 9 5 0,000 0,04051686 0,15251844 ! lymph vessel development GO:0001945 7 5 0,000 0,04051686 0,15226923 ! endochondral ossification GO:0001958 12 5 0,000 0,04051686 0,15202083 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,04051686 0,15177324 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,04051686 0,15152645 ! anagen GO:0042640 6 5 0,000 0,04051686 0,15128047 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,04051686 0,15103528 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,04051686 0,15079088 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,04051686 0,15054728 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,04051686 0,15030446 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,04051686 0,15006243 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,04051686 0,14982117 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,04051686 0,14958068 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,04051686 0,14934097 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,04051686 0,14910203 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,04051686 0,14886384 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,04051686 0,14862642 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,04051686 0,14838976 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,04051686 0,14815384 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,04051686 0,14791868 ! ovulation GO:0030728 6 5 0,000 0,04051686 0,14768426 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,04051686 0,14745058 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,04051686 0,14721764 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,04051686 0,14698544 ! response to pH GO:0009268 9 5 0,000 0,04051686 0,14675396 ! proline biosynthetic process GO:0006561 6 5 0,000 0,04051686 0,14652322 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,04051686 0,1462932 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,04051686 0,1460639 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,04051686 0,14583532 ! polyol catabolic process GO:0046174 7 5 0,000 0,04051686 0,14560745 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,04051686 0,14538029 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,04051686 0,14515384 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,04051686 0,1449281 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,04051686 0,14470305 ! nerve growth factor processing GO:0032455 7 5 0,000 0,04051686 0,14447871 ! urea metabolic process GO:0019627 6 5 0,000 0,04051686 0,14425506 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,04051686 0,1440321 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,04051686 0,14380983 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,04051686 0,14358824 ! neutrophil activation GO:0042119 5 5 0,000 0,04051686 0,14336733 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,04051686 0,14314711 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,04051686 0,14292756 ! response to food GO:0032094 5 5 0,000 0,04051686 0,14270868 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,04051686 0,14249047 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,04051686 0,14227293 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,04051686 0,14205605 ! forebrain neuron development GO:0021884 7 5 0,000 0,04051686 0,14183983 ! melanosome organization GO:0032438 7 5 0,000 0,04051686 0,14162427 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,04051686 0,14140936 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,04051686 0,1411951 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,04051686 0,14098149 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,04051686 0,14076853 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,04051686 0,14055621 ! nucleoside transport GO:0015858 6 5 0,000 0,04051686 0,14034453 ! nucleoside salvage GO:0043174 7 5 0,000 0,04051686 0,14013348 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,04051686 0,13992307 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,04051686 0,13971329 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,04051686 0,13950414 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,04051686 0,13929562 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,04051686 0,13908771 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,04051686 0,13888043 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,04051686 0,13867376 ! depyrimidination GO:0045008 8 5 0,000 0,04051686 0,13846771 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,04051686 0,13826227 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,04051686 0,13805743 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,04051686 0,13785321 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,04051686 0,13764958 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,04051686 0,13744656 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,04051686 0,13724413 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,04051686 0,1370423 ! monocyte differentiation GO:0030224 8 5 0,000 0,04051686 0,13684107 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,04051686 0,13664042 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,04051686 0,13644036 ! centrosome duplication GO:0051298 5 5 0,000 0,04051686 0,13624089 ! response to UV-C GO:0010225 6 5 0,000 0,04051686 0,136042 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,04051686 0,13584368 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,04051686 0,13564595 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,04051686 0,13544879 ! regulation of dendrite development GO:0050773 12 5 0,000 0,04051686 0,1352522 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,04051686 0,13505618 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,04051686 0,13486073 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,04051686 0,13466585 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,04051686 0,13447152 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,04051686 0,13427776 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,04051686 0,13408456 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,04051686 0,13389191 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,04051686 0,13369981 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,04051686 0,13350826 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,04051686 0,13331726 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,04051686 0,13312681 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,04051686 0,1329369 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,04051686 0,13274753 ! neural tube patterning GO:0021532 6 5 0,000 0,04051686 0,1325587 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,04051686 0,13237041 ! histone demethylation GO:0016577 9 5 0,000 0,04051686 0,13218265 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,04051686 0,13199542 ! regulation of sterol transport GO:0032371 7 5 0,000 0,04051686 0,13180872 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,04051686 0,13162255 ! enteric nervous system development GO:0048484 8 5 0,000 0,04051686 0,13143691 ! establishment of planar polarity GO:0001736 6 5 0,000 0,04051686 0,13125178 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,04051686 0,13106718 ! muscle cell proliferation GO:0033002 8 5 0,000 0,04051686 0,1308831 ! transcription termination GO:0006353 8 5 0,000 0,04051686 0,13069953 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,04051686 0,13051648 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,04051686 0,13033394 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,04051686 0,13015191 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,04051686 0,12997039 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,04051686 0,12978937 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,04051686 0,12960885 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,04051686 0,12942884 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,04051686 0,12924933 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,04051686 0,12907031 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,04051686 0,12889179 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,04051686 0,12871377 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,04051686 0,12853623 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,04051686 0,12835918 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,04051686 0,12818262 ! glial cell migration GO:0008347 10 5 0,000 0,04051686 0,12800655 ! determination of adult lifespan GO:0008340 8 5 0,000 0,04051686 0,12783096 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,04051686 0,12765584 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,04051686 0,12748121 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,04051686 0,12730706 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,04051686 0,12713338 ! neural plate development GO:0001840 6 5 0,000 0,04051686 0,12696017 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 0,000 0,04051686 0,12678744 ! regulation of sensory perception GO:0051931 6 5 0,000 0,04051686 0,12661517 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,04051686 0,12644337 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,04051686 0,12627204 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,04051686 0,12610117 ! sensory cilium assembly GO:0035058 6 5 0,000 0,04051686 0,12593077 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,04051686 0,12576082 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,04051686 0,12559133 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,04051686 0,1254223 ! spindle assembly GO:0051225 5 5 0,000 0,04051686 0,12525372 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,04051686 0,12508559 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,04051686 0,12491792 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,04051686 0,12475069 ! organ regeneration GO:0031100 7 5 0,000 0,04051686 0,12458391 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,04051686 0,12441758 ! carnitine metabolic process GO:0009437 5 5 0,000 0,04051686 0,12425169 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,04051686 0,12408624 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,04051686 0,12392123 GO:0055081|anion homeostasis, ! chromatin remodeling GO:0006338 68 39 1,000 0,04093725 0,12504075 ! developmental growth GO:0048589 62 39 1,000 0,04093725 0,12487491 ! peptide metabolic process GO:0006518 56 40 1,000 0,04286411 0,13057942 ! B cell differentiation GO:0030183 62 40 1,000 0,04286411 0,13040669 ! regulation of binding GO:0051098 151 95 2,000 0,0437725 0,13299439 ! epithelial cell differentiation GO:0030855 55 41 1,000 0,04482429 0,13601038 ! glucose transport GO:0015758 52 41 1,000 0,04482429 0,13583118 ! endosome transport GO:0016197 71 41 1,000 0,04482429 0,13565246 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,04482429 0,1354742 ! regulation of JNK cascade GO:0046328 58 41 1,000 0,04482429 0,13529641 ! regulation of response to external stimulus GO:0032101 139 96 2,000 0,04492094 0,13541042 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 2,000 0,04608429 0,13873544 ! mitochondrial transport GO:0006839 60 42 1,000 0,04681711 0,14075734 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 1,000 0,04681711 0,14057358 ! cellular component disassembly GO:0022411 64 42 1,000 0,04681711 0,1403903 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 1,000 0,04681711 0,1402075 ! hexose transport GO:0008645 54 42 1,000 0,04681711 0,14002518 GO:0015749|monosaccharide transport, ! regulation of cell shape GO:0008360 78 42 1,000 0,04681711 0,13984333 ! tRNA transcription GO:0009304 11 6 0,000 0,04842242 0,1444508 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,04842242 0,14426369 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,04842242 0,14407706 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,04842242 0,14389091 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,04842242 0,14370525 ! regulation of helicase activity GO:0051095 11 6 0,000 0,04842242 0,14352006 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,04842242 0,14333535 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,04842242 0,14315112 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,04842242 0,14296735 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,04842242 0,14278406 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,04842242 0,14260124 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,04842242 0,14241888 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,04842242 0,142237 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,04842242 0,14205557 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,04842242 0,14187461 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,04842242 0,14169411 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,04842242 0,14151406 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,04842242 0,14133448 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,04842242 0,14115535 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! neuron adhesion GO:0007158 9 6 0,000 0,04842242 0,14097667 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,04842242 0,14079844 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,04842242 0,14062067 ! signal peptide processing GO:0006465 8 6 0,000 0,04842242 0,14044334 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,04842242 0,14026646 ! mRNA stabilization GO:0048255 15 6 0,000 0,04842242 0,14009002 GO:0043489|RNA stabilization, ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,04842242 0,13991403 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,04842242 0,13973848 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,04842242 0,13956337 ! opsonization GO:0008228 8 6 0,000 0,04842242 0,1393887 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,04842242 0,13921446 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,04842242 0,13904066 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,04842242 0,13886729 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,04842242 0,13869436 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,04842242 0,13852185 ! photoreceptor cell development GO:0042461 10 6 0,000 0,04842242 0,13834977 GO:0046530|photoreceptor cell differentiation, ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,04842242 0,13817812 ! mechanosensory behavior GO:0007638 8 6 0,000 0,04842242 0,1380069 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,04842242 0,1378361 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,04842242 0,13766572 ! response to interferon-gamma GO:0034341 12 6 0,000 0,04842242 0,13749576 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,04842242 0,13732622 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,04842242 0,1371571 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,04842242 0,1369884 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,04842242 0,13682011 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,04842242 0,13665223 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,04842242 0,13648476 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,04842242 0,13631771 ! thymic T cell selection GO:0045061 12 6 0,000 0,04842242 0,13615106 ! protein lipoylation GO:0009249 10 6 0,000 0,04842242 0,13598482 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,04842242 0,13581899 ! drug transport GO:0015893 6 6 0,000 0,04842242 0,13565355 ! cysteine metabolic process GO:0006534 7 6 0,000 0,04842242 0,13548853 ! activation of caspase activity by cytochrome c GO:0008635 10 6 0,000 0,04842242 0,1353239 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,04842242 0,13515967 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,04842242 0,13499584 ! histidine metabolic process GO:0006547 6 6 0,000 0,04842242 0,13483241 GO:0009075|histidine family amino acid metabolic process, ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,04842242 0,13466937 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,04842242 0,13450672 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,04842242 0,13434447 ! adenohypophysis development GO:0021984 10 6 0,000 0,04842242 0,13418261 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,04842242 0,13402114 ! hyperosmotic response GO:0006972 8 6 0,000 0,04842242 0,13386006 ! microtubule nucleation GO:0007020 10 6 0,000 0,04842242 0,13369936 ! ER overload response GO:0006983 7 6 0,000 0,04842242 0,13353905 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,04842242 0,13337912 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,04842242 0,13321958 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,04842242 0,13306042 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,04842242 0,13290163 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,04842242 0,13274323 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,04842242 0,1325852 ! response to dietary excess GO:0002021 7 6 0,000 0,04842242 0,13242755 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,04842242 0,13227027 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,04842242 0,13211337 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,04842242 0,13195683 ! purine salvage GO:0043101 8 6 0,000 0,04842242 0,13180067 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,04842242 0,13164488 ! neuron apoptosis GO:0051402 8 6 0,000 0,04842242 0,13148945 ! organic alcohol transport GO:0015850 9 6 0,000 0,04842242 0,1313344 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,04842242 0,1311797 ! T cell mediated immunity GO:0002456 12 6 0,000 0,04842242 0,13102537 ! carnitine transport GO:0015879 8 6 0,000 0,04842242 0,13087141 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,04842242 0,1307178 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,04842242 0,13056456 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,04842242 0,13041167 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,04842242 0,13025914 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,04842242 0,13010697 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,04842242 0,12995516 ! parturition GO:0007567 12 6 0,000 0,04842242 0,12980369 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,04842242 0,12965258 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,04842242 0,12950182 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,04842242 0,12935141 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,04842242 0,12920135 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,04842242 0,12905164 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,04842242 0,12890228 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,04842242 0,12875326 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,04842242 0,12860458 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,04842242 0,12845625 ! macrophage differentiation GO:0030225 10 6 0,000 0,04842242 0,12830826 ! astrocyte development GO:0014002 14 6 0,000 0,04842242 0,12816061 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,04842242 0,1280133 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,04842242 0,12786632 ! interaction with symbiont GO:0051702 8 6 0,000 0,04842242 0,12771969 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,04842242 0,12757339 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,04842242 0,12742742 ! eating behavior GO:0042755 6 6 0,000 0,04842242 0,12728179 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,04842242 0,12713649 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,04842242 0,12699153 ! response to copper ion GO:0046688 9 6 0,000 0,04842242 0,12684689 ! DNA topological change GO:0006265 8 6 0,000 0,04842242 0,12670258 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,04842242 0,1265586 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,04842242 0,12641495 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,04842242 0,12627162 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,04842242 0,12612862 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,04842242 0,12598594 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,04842242 0,12584358 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,04842242 0,12570154 ! gas homeostasis GO:0033483 11 6 0,000 0,04842242 0,12555983 ! hair follicle maturation GO:0048820 7 6 0,000 0,04842242 0,12541843 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,04842242 0,12527735 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,04842242 0,12513659 ! Schwann cell development GO:0014044 14 6 0,000 0,04842242 0,12499615 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,04842242 0,12485602 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,04842242 0,1247162 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,04842242 0,1245767 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,04842242 0,12443751 ! histone ubiquitination GO:0016574 7 6 0,000 0,04842242 0,12429863 ! regulation of meiosis GO:0040020 10 6 0,000 0,04842242 0,12416005 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,04842242 0,12402179 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,04842242 0,12388384 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,04842242 0,12374619 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,04842242 0,12360884 ! membrane to membrane docking GO:0022614 12 6 0,000 0,04842242 0,1234718 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,04842242 0,12333507 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,04842242 0,12319864 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,04842242 0,12306251 ! receptor internalization GO:0031623 9 6 0,000 0,04842242 0,12292668 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,04842242 0,12279114 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,04842242 0,12265591 ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,04842242 0,12252098 ! protein deubiquitination GO:0016579 8 6 0,000 0,04842242 0,12238634 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,04842242 0,122252 ! negative regulation of neuroblast proliferation GO:0007406 18 6 0,000 0,04842242 0,12211795 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,04842242 0,12198419 ! axonal fasciculation GO:0007413 9 6 0,000 0,04842242 0,12185073 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,04842242 0,12171756 ! thiamin metabolic process GO:0006772 6 6 0,000 0,04842242 0,12158468 ! midbrain development GO:0030901 6 6 0,000 0,04842242 0,12145209 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,04842242 0,12131979 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,04842242 0,12118778 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,04842242 0,12105605 ! progesterone metabolic process GO:0042448 8 6 0,000 0,04842242 0,12092461 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,04842242 0,12079346 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,04842242 0,12066259 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,04842242 0,120532 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,04842242 0,1204017 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,04842242 0,12027167 ! adult feeding behavior GO:0008343 6 6 0,000 0,04842242 0,12014193 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,04842242 0,12001247 ! blastocyst growth GO:0001832 15 6 0,000 0,04842242 0,11988328 ! pigment granule transport GO:0051904 12 6 0,000 0,04842242 0,11975437 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,04842242 0,11962574 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,04842242 0,11949739 ! catecholamine transport GO:0051937 7 6 0,000 0,04842242 0,11936931 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,04842242 0,11924151 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,04842242 0,11911398 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,04842242 0,11898672 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,04842242 0,11885973 ! protein prenylation GO:0018342 10 6 0,000 0,04842242 0,11873301 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,04842242 0,11860657 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 0,000 0,04842242 0,11848039 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,04842242 0,11835448 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,04842242 0,11822884 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,04842242 0,11810347 ! extracellular structure organization GO:0043062 156 99 2,000 0,04845552 0,118059 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 2,000 0,04845552 0,11793407 ! positive regulation of binding GO:0051099 59 43 1,000 0,04884192 0,11874886 ! activation of caspase activity GO:0006919 65 43 1,000 0,04884192 0,11862346 ! vesicle organization GO:0016050 79 43 1,000 0,04884192 0,11849833 ! negative regulation of cell migration GO:0030336 92 44 1,000 0,05089806 0,12335673 ! regulation of translational initiation GO:0006446 64 45 1,000 0,05298488 0,12827918 ! cell maturation GO:0048469 60 45 1,000 0,05298488 0,12814429 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,0562633 0,13593024 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,0562633 0,1357876 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,0562633 0,13564527 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,0562633 0,13550323 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,0562633 0,13536149 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,0562633 0,13522005 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,0562633 0,1350789 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,0562633 0,13493805 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,0562633 0,13479749 ! reproductive behavior GO:0019098 12 7 0,000 0,0562633 0,13465722 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,0562633 0,13451724 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,0562633 0,13437756 ! oligopeptide transport GO:0006857 11 7 0,000 0,0562633 0,13423816 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,0562633 0,13409905 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,0562633 0,13396023 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,0562633 0,1338217 ! RNA methylation GO:0001510 11 7 0,000 0,0562633 0,13368346 ! pericardium development GO:0060039 8 7 0,000 0,0562633 0,1335455 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,0562633 0,13340782 ! fibril organization GO:0043206 13 7 0,000 0,0562633 0,13327043 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,0562633 0,13313332 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,0562633 0,13299649 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,0562633 0,13285994 ! lipoprotein transport GO:0042953 9 7 0,000 0,0562633 0,13272368 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,0562633 0,13258769 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,0562633 0,13245198 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,0562633 0,13231655 ! estrogen metabolic process GO:0008210 14 7 0,000 0,0562633 0,1321814 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,0562633 0,13204652 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,0562633 0,13191191 ! chemosensory behavior GO:0007635 9 7 0,000 0,0562633 0,13177758 ! microtubule bundle formation GO:0001578 8 7 0,000 0,0562633 0,13164353 ! T-helper 1 type immune response GO:0042088 11 7 0,000 0,0562633 0,13150974 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,0562633 0,13137623 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,0562633 0,13124299 ! leukocyte degranulation GO:0043299 10 7 0,000 0,0562633 0,13111002 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,0562633 0,13097731 ! reflex GO:0060004 12 7 0,000 0,0562633 0,13084488 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,0562633 0,13071271 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,0562633 0,13058081 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,0562633 0,13044918 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,0562633 0,13031781 ! spinal cord patterning GO:0021511 7 7 0,000 0,0562633 0,13018671 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,0562633 0,13005587 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,0562633 0,12992529 ! adrenal gland development GO:0030325 17 7 0,000 0,0562633 0,12979497 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,0562633 0,12966492 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,0562633 0,12953512 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,0562633 0,12940559 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,0562633 0,12927631 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,0562633 0,12914729 ! endosome organization GO:0007032 10 7 0,000 0,0562633 0,12901853 ! thyroid hormone generation GO:0006590 11 7 0,000 0,0562633 0,12889003 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,0562633 0,12876178 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,0562633 0,12863378 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,0562633 0,12850604 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,0562633 0,12837856 ! galactose metabolic process GO:0006012 10 7 0,000 0,0562633 0,12825132 ! vesicle fusion GO:0006906 15 7 0,000 0,0562633 0,12812434 ! intracellular pH reduction GO:0051452 10 7 0,000 0,0562633 0,12799761 GO:0045851|pH reduction, ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,0562633 0,12787113 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,0562633 0,1277449 ! retinol metabolic process GO:0042572 9 7 0,000 0,0562633 0,12761892 ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,0562633 0,12749319 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,0562633 0,1273677 ! rRNA modification GO:0000154 12 7 0,000 0,0562633 0,12724246 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,0562633 0,12711747 ! G1 DNA damage checkpoint GO:0031571 18 7 0,000 0,0562633 0,12699272 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,0562633 0,12686822 ! intermediate filament organization GO:0045109 11 7 0,000 0,0562633 0,12674396 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,0562633 0,12661995 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,0562633 0,12649617 ! fibrinolysis GO:0042730 9 7 0,000 0,0562633 0,12637264 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,0562633 0,12624935 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,0562633 0,1261263 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,0562633 0,12600349 ! response to tropane GO:0014073 13 7 0,000 0,0562633 0,12588092 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,0562633 0,12575859 ! melanosome localization GO:0032400 10 7 0,000 0,0562633 0,12563649 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,0562633 0,12551463 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,0562633 0,12539301 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,0562633 0,12527162 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,0562633 0,12515047 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,0562633 0,12502955 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,0562633 0,12490887 ! mast cell activation GO:0045576 9 7 0,000 0,0562633 0,12478841 ! multicellular organismal aging GO:0010259 11 7 0,000 0,0562633 0,12466819 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,0562633 0,12454821 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,0562633 0,12442845 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,0562633 0,12430892 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,0562633 0,12418962 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,0562633 0,12407055 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,0562633 0,12395171 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,0562633 0,1238331 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,0562633 0,12371471 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,0562633 0,12359655 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,0562633 0,12347861 ! regulation of lipid transport GO:0032368 13 7 0,000 0,0562633 0,1233609 ! response to tumor cell GO:0002347 12 7 0,000 0,0562633 0,12324342 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,0562633 0,12312615 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,0562633 0,12300911 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,0562633 0,12289229 ! diuresis GO:0030146 12 7 0,000 0,0562633 0,1227757 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,0562633 0,12265932 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,0562633 0,12254317 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,0562633 0,12242723 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,0562633 0,12231152 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,0562633 0,12219602 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,0562633 0,12208074 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,0562633 0,12196568 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,0562633 0,12185083 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,0562633 0,1217362 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,0562633 0,12162179 ! lymph node development GO:0048535 9 7 0,000 0,0562633 0,12150759 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,0562633 0,12139361 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,0562633 0,12127984 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,0562633 0,12116628 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,0562633 0,12105293 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,0562633 0,1209398 ! ATP catabolic process GO:0006200 10 7 0,000 0,0562633 0,12082688 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,0562633 0,12071417 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,0562633 0,12060166 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,0562633 0,12048937 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,0562633 0,12037729 ! muscle adaptation GO:0043500 12 7 0,000 0,0562633 0,12026541 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,0562633 0,12015375 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,0562633 0,12004229 ! retina homeostasis GO:0001895 9 7 0,000 0,0562633 0,11993103 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,0562633 0,11981999 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,0562633 0,11970915 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,0562633 0,11959851 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,0562633 0,11948808 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,0562633 0,11937785 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,0562633 0,11926782 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,0562633 0,119158 ! response to estrogen stimulus GO:0043627 74 47 1,000 0,05724804 0,121132 ! endocrine system development GO:0035270 83 47 1,000 0,05724804 0,12102066 ! negative regulation of immune system process GO:0002683 73 47 1,000 0,05724804 0,12090953 ! glutamine family amino acid metabolic process GO:0009064 59 47 1,000 0,05724804 0,12079861 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,05724804 0,12068788 ! positive regulation of caspase activity GO:0043280 72 48 1,000 0,05942312 0,12515859 GO:0010952|positive regulation of peptidase activity, ! regulation of DNA replication GO:0006275 75 48 1,000 0,05942312 0,12504408 ! regulation of angiogenesis GO:0045765 94 49 1,000 0,06162639 0,12956188 ! regulation of intracellular transport GO:0032386 78 49 1,000 0,06162639 0,12944356 ! maintenance of location GO:0051235 84 49 1,000 0,06162639 0,12932546 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,06385724 0,13388483 ! lipid modification GO:0030258 73 50 1,000 0,06385724 0,13376289 ! regulation of multicellular organism growth GO:0040014 65 50 1,000 0,06385724 0,13364118 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,06404001 0,13390184 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,06404001 0,13378023 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,06404001 0,13365883 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,06404001 0,13353765 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,06404001 0,13341669 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,06404001 0,13329595 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,06404001 0,13317543 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,06404001 0,13305513 ! phosphate transport GO:0006817 10 8 0,000 0,06404001 0,13293504 ! N-glycan processing GO:0006491 12 8 0,000 0,06404001 0,13281517 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,06404001 0,13269552 ! UTP metabolic process GO:0046051 8 8 0,000 0,06404001 0,13257608 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,06404001 0,13245686 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,06404001 0,13233785 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,06404001 0,13221906 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 0,000 0,06404001 0,13210047 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,06404001 0,1319821 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,06404001 0,13186395 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,06404001 0,131746 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,06404001 0,13162827 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,06404001 0,13151074 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,06404001 0,13139342 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,06404001 0,13127632 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,06404001 0,13115942 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,06404001 0,13104273 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,06404001 0,13092625 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,06404001 0,13080997 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,06404001 0,1306939 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,06404001 0,13057804 ! astrocyte differentiation GO:0048708 16 8 0,000 0,06404001 0,13046238 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,06404001 0,13034693 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,06404001 0,13023168 ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,06404001 0,13011663 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,06404001 0,13000179 ! positive regulation of endothelial cell migration GO:0010595 18 8 0,000 0,06404001 0,12988715 ! macrophage activation GO:0042116 12 8 0,000 0,06404001 0,12977271 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,06404001 0,12965848 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,06404001 0,12954444 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,06404001 0,12943061 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,06404001 0,12931697 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,06404001 0,12920353 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,06404001 0,1290903 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,06404001 0,12897726 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,06404001 0,12886442 ! ruffle organization GO:0031529 11 8 0,000 0,06404001 0,12875177 ! osteoblast development GO:0002076 13 8 0,000 0,06404001 0,12863933 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,06404001 0,12852708 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,06404001 0,12841502 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,06404001 0,12830316 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,06404001 0,1281915 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,06404001 0,12808003 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,06404001 0,12796875 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,06404001 0,12785766 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,06404001 0,12774677 ! brain morphogenesis GO:0048854 20 8 0,000 0,06404001 0,12763607 ! oligodendrocyte development GO:0014003 8 8 0,000 0,06404001 0,12752557 ! segment specification GO:0007379 10 8 0,000 0,06404001 0,12741525 ! cellular extravasation GO:0045123 11 8 0,000 0,06404001 0,12730512 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,06404001 0,12719519 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,06404001 0,12708544 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,06404001 0,12697589 ! snRNA metabolic process GO:0016073 10 8 0,000 0,06404001 0,12686652 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,06404001 0,12675734 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,06404001 0,12664835 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,06404001 0,12653954 ! nucleosome disassembly GO:0006337 12 8 0,000 0,06404001 0,12643093 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,06404001 0,12632249 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,06404001 0,12621425 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,06404001 0,12610619 ! icosanoid secretion GO:0032309 12 8 0,000 0,06404001 0,12599831 GO:0050482|arachidonic acid secretion, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,06404001 0,12589062 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,06404001 0,12578312 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,06404001 0,12567579 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,06404001 0,12556865 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,06404001 0,12546169 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,06404001 0,12535492 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,06404001 0,12524832 ! sterol catabolic process GO:0016127 9 8 0,000 0,06404001 0,12514191 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,06404001 0,12503568 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,06404001 0,12492963 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,06404001 0,12482375 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,06404001 0,12471806 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,06404001 0,12461255 ! prophase GO:0051324 11 8 0,000 0,06404001 0,12450721 ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,06404001 0,12440205 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,06404001 0,12429707 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,06404001 0,12419227 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,06404001 0,12408764 ! hormone catabolic process GO:0042447 13 8 0,000 0,06404001 0,12398319 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,06404001 0,12387891 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,06404001 0,12377481 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,06404001 0,12367089 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,06404001 0,12356714 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,06404001 0,12346356 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,06404001 0,12336016 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,06404001 0,12325693 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,06404001 0,12315387 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,06404001 0,12305098 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,06404001 0,12294827 ! lamellipodium assembly GO:0030032 9 8 0,000 0,06404001 0,12284573 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,06404001 0,12274336 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,06404001 0,12264116 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 0,000 0,06404001 0,12253913 ! muscle fiber development GO:0048747 74 51 1,000 0,06611508 0,12640456 ! regulation of protein catabolic process GO:0042176 77 51 1,000 0,06611508 0,12629957 ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,06611508 0,12619476 ! negative regulation of cell motion GO:0051271 104 51 1,000 0,06611508 0,12609012 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,06611508 0,12598565 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,06839931 0,13023047 ! aging GO:0007568 79 52 1,000 0,06839931 0,13012276 ! establishment of organelle localization GO:0051656 85 52 1,000 0,06839931 0,13001522 ! regulation of neurotransmitter levels GO:0001505 73 53 1,000 0,07070936 0,13429523 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,07175309 0,1361651 ! telencephalon cell migration GO:0022029 16 9 0,000 0,07175309 0,13605284 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,07175309 0,13594077 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,07175309 0,13582889 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,07175309 0,13571719 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,07175309 0,13560567 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,07175309 0,13549433 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,07175309 0,13538318 ! GTP metabolic process GO:0046039 9 9 0,000 0,07175309 0,13527221 ! elastic fiber assembly GO:0048251 13 9 0,000 0,07175309 0,13516142 ! social behavior GO:0035176 14 9 0,000 0,07175309 0,13505082 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,07175309 0,13494039 ! artery development GO:0060840 19 9 0,000 0,07175309 0,13483014 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,07175309 0,13472008 ! response to pain GO:0048265 16 9 0,000 0,07175309 0,13461019 ! protein complex disassembly GO:0043241 17 9 0,000 0,07175309 0,13450049 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,07175309 0,13439096 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,07175309 0,13428161 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,07175309 0,13417244 ! lung alveolus development GO:0048286 17 9 0,000 0,07175309 0,13406344 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,07175309 0,13395462 ! negative regulation of striated muscle development GO:0045843 11 9 0,000 0,07175309 0,13384598 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,07175309 0,13373752 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,07175309 0,13362923 ! ventral spinal cord development GO:0021517 11 9 0,000 0,07175309 0,13352111 ! protein targeting to ER GO:0045047 19 9 0,000 0,07175309 0,13341317 ! endoderm development GO:0007492 12 9 0,000 0,07175309 0,13330541 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,07175309 0,13319782 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,07175309 0,1330904 ! arginine catabolic process GO:0006527 10 9 0,000 0,07175309 0,13298316 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,07175309 0,13287608 ! L-serine metabolic process GO:0006563 13 9 0,000 0,07175309 0,13276919 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,07175309 0,13266246 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,07175309 0,1325559 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,07175309 0,13244952 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,07175309 0,1323433 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,07175309 0,13223726 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,07175309 0,13213138 ! mannose metabolic process GO:0006013 9 9 0,000 0,07175309 0,13202568 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,07175309 0,13192014 ! receptor clustering GO:0043113 15 9 0,000 0,07175309 0,13181477 ! epithelial cell development GO:0002064 10 9 0,000 0,07175309 0,13170957 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,07175309 0,13160454 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,07175309 0,13149968 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,07175309 0,13139498 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,07175309 0,13129045 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,07175309 0,13118609 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,07175309 0,13108189 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,07175309 0,13097785 ! blastoderm segmentation GO:0007350 11 9 0,000 0,07175309 0,13087399 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,07175309 0,13077028 ! DNA ligation GO:0006266 14 9 0,000 0,07175309 0,13066674 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,07175309 0,13056337 ! response to amine stimulus GO:0014075 13 9 0,000 0,07175309 0,13046016 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,07175309 0,13035711 ! erythrocyte development GO:0048821 11 9 0,000 0,07175309 0,13025422 ! renal water homeostasis GO:0003091 14 9 0,000 0,07175309 0,1301515 ! postreplication repair GO:0006301 11 9 0,000 0,07175309 0,13004893 ! mRNA cleavage GO:0006379 13 9 0,000 0,07175309 0,12994653 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,07175309 0,12984429 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,07175309 0,12974221 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,07175309 0,1296403 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,07175309 0,12953854 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,07175309 0,12943694 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,07175309 0,1293355 ! acid secretion GO:0046717 14 9 0,000 0,07175309 0,12923422 ! musculoskeletal movement GO:0050881 11 9 0,000 0,07175309 0,1291331 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,07175309 0,12903213 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,07175309 0,12893133 ! purine base metabolic process GO:0006144 18 9 0,000 0,07175309 0,12883068 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,07175309 0,12873018 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,07175309 0,12862985 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,07175309 0,12852967 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,07175309 0,12842965 ! detection of calcium ion GO:0005513 13 9 0,000 0,07175309 0,12832978 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,07175309 0,12823007 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,07175309 0,12813051 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,07175309 0,12803111 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,07175309 0,12793186 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,07175309 0,12783276 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,07175309 0,12773382 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,07175309 0,12763503 ! prepulse inhibition GO:0060134 14 9 0,000 0,07175309 0,1275364 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,07175309 0,12743791 ! insulin secretion GO:0030073 17 9 0,000 0,07175309 0,12733958 ! establishment of cell polarity GO:0030010 12 9 0,000 0,07175309 0,1272414 ! nucleus localization GO:0051647 15 9 0,000 0,07175309 0,12714337 ! regulation of synapse organization GO:0050807 12 9 0,000 0,07175309 0,12704549 ! amino acid transport GO:0006865 84 54 1,000 0,07304464 0,12923283 ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,07304464 0,1291335 ! DNA catabolic process GO:0006308 67 54 1,000 0,07304464 0,12903432 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,07304464 0,12893529 ! exocytosis GO:0006887 74 55 1,000 0,07540461 0,13299892 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 0,07778869 0,13709883 ! regulation of lipid metabolic process GO:0019216 84 56 1,000 0,07778869 0,13699386 ! negative regulation of muscle development GO:0048635 12 10 0,000 0,07940303 0,1397299 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,07940303 0,13962307 ! neuron fate specification GO:0048665 11 10 0,000 0,07940303 0,13951641 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,07940303 0,13940991 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,07940303 0,13930357 ! thyroid gland development GO:0030878 19 10 0,000 0,07940303 0,13919739 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,07940303 0,13909138 ! synapsis GO:0007129 13 10 0,000 0,07940303 0,13898552 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,07940303 0,13887983 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,07940303 0,1387743 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,07940303 0,13866893 GO:0007520|myoblast fusion, ! sulfate transport GO:0008272 12 10 0,000 0,07940303 0,13856372 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,07940303 0,13845867 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,07940303 0,13835377 ! androgen metabolic process GO:0008209 13 10 0,000 0,07940303 0,13824904 ! phospholipid efflux GO:0033700 16 10 0,000 0,07940303 0,13814446 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,07940303 0,13804004 ! blood vessel remodeling GO:0001974 21 10 0,000 0,07940303 0,13793578 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,07940303 0,13783168 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,07940303 0,13772774 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,07940303 0,13762395 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,07940303 0,13752032 ! pathogenesis GO:0009405 13 10 0,000 0,07940303 0,13741684 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,07940303 0,13731352 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,07940303 0,13721035 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,07940303 0,13710734 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,07940303 0,13700449 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 0,000 0,07940303 0,13690178 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,07940303 0,13679924 ! melanocyte differentiation GO:0030318 15 10 0,000 0,07940303 0,13669684 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,07940303 0,1365946 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,07940303 0,13649251 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,07940303 0,13639057 ! response to X-ray GO:0010165 16 10 0,000 0,07940303 0,13628879 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,07940303 0,13618716 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,07940303 0,13608568 ! forebrain cell migration GO:0021885 17 10 0,000 0,07940303 0,13598435 ! lipid digestion GO:0044241 15 10 0,000 0,07940303 0,13588317 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,07940303 0,13578214 ! UV protection GO:0009650 14 10 0,000 0,07940303 0,13568126 ! entry into host cell GO:0030260 20 10 0,000 0,07940303 0,13558053 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,07940303 0,13547995 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,07940303 0,13537953 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 0,000 0,07940303 0,13527924 ! regulation of bone resorption GO:0045124 24 10 0,000 0,07940303 0,13517911 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,07940303 0,13507913 ! regulation of organ growth GO:0046620 11 10 0,000 0,07940303 0,13497929 ! response to dsRNA GO:0043331 18 10 0,000 0,07940303 0,1348796 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,07940303 0,13478006 ! embryonic axis specification GO:0000578 12 10 0,000 0,07940303 0,13468066 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,07940303 0,13458141 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,07940303 0,13448231 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,07940303 0,13438335 ! fucose catabolic process GO:0019317 16 10 0,000 0,07940303 0,13428454 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,07940303 0,13418588 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,07940303 0,13408736 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,07940303 0,13398898 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,07940303 0,13389075 ! zymogen activation GO:0031638 14 10 0,000 0,07940303 0,13379266 ! salivary gland development GO:0007431 22 10 0,000 0,07940303 0,13369471 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,07940303 0,13359691 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,07940303 0,13349925 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,07940303 0,13340174 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,07940303 0,13330436 ! positive regulation of leukocyte migration GO:0002687 23 10 0,000 0,07940303 0,13320713 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,07940303 0,13311004 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,07940303 0,13301309 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,07940303 0,13291629 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,07940303 0,13281962 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,07940303 0,1327231 ! detection of bacterium GO:0016045 10 10 0,000 0,07940303 0,13262671 ! embryonic gut development GO:0048566 11 10 0,000 0,07940303 0,13253046 ! activation of innate immune response GO:0002218 10 10 0,000 0,07940303 0,13243436 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,07940303 0,13233839 ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,07940303 0,13224256 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,07940303 0,13214687 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,07940303 0,13205132 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,07940303 0,13195591 ! carbohydrate transport GO:0008643 74 57 1,000 0,08019633 0,13317803 ! chromosome segregation GO:0007059 83 57 1,000 0,08019633 0,13308194 ! coenzyme biosynthetic process GO:0009108 67 57 1,000 0,08019633 0,13298599 ! secondary metabolic process GO:0019748 84 57 1,000 0,08019633 0,13289018 ! developmental maturation GO:0021700 75 57 1,000 0,08019633 0,1327945 ! viral reproductive process GO:0022415 87 58 1,000 0,082627 0,13672094 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 0,082627 0,13662265 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 1,000 0,08508016 0,14057785 ! activation of MAPK activity GO:0000187 84 59 1,000 0,08508016 0,14047693 ! rRNA transcription GO:0009303 17 11 0,000 0,08699037 0,14352787 ! respiratory burst GO:0045730 14 11 0,000 0,08699037 0,14342499 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,08699037 0,14332225 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,08699037 0,14321965 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,08699037 0,14311721 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,08699037 0,14301491 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,08699037 0,14291275 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,08699037 0,14281075 ! RNA polyadenylation GO:0043631 19 11 0,000 0,08699037 0,14270888 ! mating GO:0007618 14 11 0,000 0,08699037 0,14260717 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,08699037 0,1425056 ! T cell proliferation GO:0042098 20 11 0,000 0,08699037 0,14240417 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,08699037 0,14230288 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 0,000 0,08699037 0,14220175 ! bone resorption GO:0045453 16 11 0,000 0,08699037 0,14210075 ! regulated secretory pathway GO:0045055 14 11 0,000 0,08699037 0,1419999 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,08699037 0,14189919 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,08699037 0,14179862 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,08699037 0,1416982 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,08699037 0,14159792 ! syncytium formation GO:0006949 15 11 0,000 0,08699037 0,14149778 ! plasma membrane organization GO:0007009 18 11 0,000 0,08699037 0,14139778 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,08699037 0,14129792 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,08699037 0,1411982 ! regulation of intracellular pH GO:0051453 17 11 0,000 0,08699037 0,14109863 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,08699037 0,14099919 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,08699037 0,1408999 ! adult heart development GO:0007512 11 11 0,000 0,08699037 0,14080074 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,08699037 0,14070173 ! temperature homeostasis GO:0001659 16 11 0,000 0,08699037 0,14060285 ! L-glutamate transport GO:0015813 16 11 0,000 0,08699037 0,14050411 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,08699037 0,14040551 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,08699037 0,14030705 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,08699037 0,14020873 ! stem cell development GO:0048864 29 11 0,000 0,08699037 0,14011054 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,08699037 0,1400125 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,08699037 0,13991458 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,08699037 0,13981681 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,08699037 0,13971917 ! vasoconstriction GO:0042310 15 11 0,000 0,08699037 0,13962167 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,08699037 0,13952431 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,08699037 0,13942708 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,08699037 0,13932998 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,08699037 0,13923302 ! ribosome assembly GO:0042255 13 11 0,000 0,08699037 0,1391362 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,08699037 0,13903951 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,08699037 0,13894296 ! chromatin silencing GO:0006342 19 11 0,000 0,08699037 0,13884653 ! nucleosome positioning GO:0016584 13 11 0,000 0,08699037 0,13875025 ! regulation of isotype switching GO:0045191 19 11 0,000 0,08699037 0,13865409 ! regulation of leukocyte migration GO:0002685 24 11 0,000 0,08699037 0,13855807 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,08699037 0,13846218 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,08699037 0,13836643 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,08699037 0,13827081 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,08699037 0,13817531 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,08699037 0,13807996 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,08699037 0,13798473 ! male genitalia development GO:0030539 13 11 0,000 0,08699037 0,13788963 ! cholesterol efflux GO:0033344 19 11 0,000 0,08699037 0,13779467 ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,08699037 0,13769983 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,08699037 0,13760513 ! germ cell migration GO:0008354 18 11 0,000 0,08699037 0,13751055 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,08699037 0,13741611 ! defense response to fungus GO:0050832 12 11 0,000 0,08699037 0,1373218 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,08699037 0,13722761 ! lysogeny GO:0030069 18 11 0,000 0,08699037 0,13713355 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,08699037 0,13703963 ! acrosome reaction GO:0007340 13 11 0,000 0,08699037 0,13694583 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,08699037 0,13685216 ! phosphoinositide metabolic process GO:0030384 87 60 1,000 0,08755527 0,1376467 ! regulation of cellular response to stress GO:0080135 85 61 1,000 0,09005182 0,14147485 ! organelle localization GO:0051640 96 62 1,000 0,09256929 0,14533063 ! lactation GO:0007595 20 12 0,000 0,09451561 0,14828506 ! reproductive cellular process GO:0048610 14 12 0,000 0,09451561 0,14818398 ! tRNA modification GO:0006400 14 12 0,000 0,09451561 0,14808304 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,09451561 0,14798223 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,09451561 0,14788156 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,09451561 0,14778103 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,09451561 0,14768064 ! non-recombinational repair GO:0000726 19 12 0,000 0,09451561 0,14758038 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,09451561 0,14748026 ! peroxisomal transport GO:0043574 21 12 0,000 0,09451561 0,14738027 ! cartilage condensation GO:0001502 18 12 0,000 0,09451561 0,14728042 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,09451561 0,1471807 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,09451561 0,14708112 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,09451561 0,14698167 ! heart looping GO:0001947 15 12 0,000 0,09451561 0,14688236 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,09451561 0,14678319 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,09451561 0,14668414 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,09451561 0,14658523 ! arginine metabolic process GO:0006525 13 12 0,000 0,09451561 0,14648645 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,09451561 0,14638781 ! methionine metabolic process GO:0006555 13 12 0,000 0,09451561 0,1462893 ! Golgi organization GO:0007030 18 12 0,000 0,09451561 0,14619092 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,09451561 0,14609267 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,09451561 0,14599456 ! monoamine transport GO:0015844 13 12 0,000 0,09451561 0,14589658 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,09451561 0,14579872 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,09451561 0,145701 ! L-amino acid transport GO:0015807 20 12 0,000 0,09451561 0,14560341 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,09451561 0,14550596 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,09451561 0,14540863 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,09451561 0,14531143 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,09451561 0,14521436 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,09451561 0,14511742 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,09451561 0,14502061 ! cerebellum development GO:0021549 13 12 0,000 0,09451561 0,14492393 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,09451561 0,14482738 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,09451561 0,14473096 ! histone methylation GO:0016571 15 12 0,000 0,09451561 0,14463466 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,09451561 0,1445385 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,09451561 0,14444246 ! regulation of epidermis development GO:0045682 17 12 0,000 0,09451561 0,14434655 ! intestinal absorption GO:0050892 19 12 0,000 0,09451561 0,14425076 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,09451561 0,1441551 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,09451561 0,14405957 ! regulation of mRNA stability GO:0043488 27 12 0,000 0,09451561 0,14396417 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,09451561 0,14386889 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 0,000 0,09451561 0,14377374 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,09451561 0,14367872 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,09451561 0,14358382 ! microspike assembly GO:0030035 23 12 0,000 0,09451561 0,14348904 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,09451561 0,14339439 ! response to cold GO:0009409 14 12 0,000 0,09451561 0,14329987 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,09510717 0,14410178 GO:0090046|regulation of transcription regulator activity, ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,09510717 0,14400691 ! viral reproduction GO:0016032 92 63 1,000 0,09510717 0,14391217 ! regulation of lipase activity GO:0060191 109 63 1,000 0,09510717 0,14381755 ! regulation of caspase activity GO:0043281 97 65 1,000 0,10024217 0,15148292 ! B cell activation GO:0042113 104 65 1,000 0,10024217 0,15138345 ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 0,10024217 0,15128412 ! positive regulation of T cell activation GO:0050870 94 65 1,000 0,10024217 0,15118492 ! protein oligomerization GO:0051259 100 65 1,000 0,10024217 0,15108585 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,10197925 0,15360332 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,10197925 0,15350279 ! cGMP metabolic process GO:0046068 16 13 0,000 0,10197925 0,1534024 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,10197925 0,15330213 ! water transport GO:0006833 17 13 0,000 0,10197925 0,153202 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,10197925 0,153102 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,10197925 0,15300213 ! lipid localization GO:0010876 24 13 0,000 0,10197925 0,15290239 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,10197925 0,15280278 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,10197925 0,1527033 ! organelle fusion GO:0048284 28 13 0,000 0,10197925 0,15260395 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,10197925 0,15250472 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,10197925 0,15240563 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,10197925 0,15230666 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,10197925 0,15220783 ! response to hexose stimulus GO:0009746 19 13 0,000 0,10197925 0,15210912 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,10197925 0,15201054 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,10197925 0,15191209 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,10197925 0,15181376 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,10197925 0,15171557 ! NAD metabolic process GO:0019674 21 13 0,000 0,10197925 0,15161749 ! exocrine system development GO:0035272 27 13 0,000 0,10197925 0,15151955 ! regulation of exocytosis GO:0017157 17 13 0,000 0,10197925 0,15142173 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,10197925 0,15132404 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,10197925 0,15122648 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,10197925 0,15112904 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,10197925 0,15103172 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,10197925 0,15093453 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,10197925 0,15083747 ! genitalia development GO:0048806 15 13 0,000 0,10197925 0,15074053 ! regulation of cellular pH GO:0030641 20 13 0,000 0,10197925 0,15064371 ! tissue regeneration GO:0042246 21 13 0,000 0,10197925 0,15054702 ! cofactor transport GO:0051181 19 13 0,000 0,10197925 0,15045046 ! NADP metabolic process GO:0006739 18 13 0,000 0,10197925 0,15035402 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,10197925 0,1502577 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,10197925 0,1501615 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,10197925 0,15006543 ! gas transport GO:0015669 18 13 0,000 0,10197925 0,14996948 ! regulation of RNA stability GO:0043487 28 13 0,000 0,10197925 0,14987365 ! heme biosynthetic process GO:0006783 20 13 0,000 0,10197925 0,14977795 ! regulation of axon extension GO:0030516 23 13 0,000 0,10197925 0,14968236 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,10197925 0,1495869 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,10197925 0,14949156 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,10197925 0,14939635 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,10197925 0,14930125 ! axon guidance GO:0007411 99 66 1,000 0,10283831 0,15046318 ! regulation of endopeptidase activity GO:0052548 99 67 1,000 0,1054529 0,1541905 ! rhythmic process GO:0048511 105 68 1,000 0,10808546 0,15793936 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,10938179 0,15973213 ! superoxide anion generation GO:0042554 18 14 0,000 0,10938179 0,15963078 ! neuron maturation GO:0042551 21 14 0,000 0,10938179 0,15952956 ! regulation of S phase GO:0033261 18 14 0,000 0,10938179 0,15942846 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,10938179 0,15932749 ! myotube differentiation GO:0014902 21 14 0,000 0,10938179 0,15922665 ! inositol metabolic process GO:0006020 20 14 0,000 0,10938179 0,15912594 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,10938179 0,15902535 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,10938179 0,15892489 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,10938179 0,15882456 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,10938179 0,15872436 ! gene silencing by RNA GO:0031047 20 14 0,000 0,10938179 0,15862428 ! response to cAMP GO:0051591 19 14 0,000 0,10938179 0,15852433 ! startle response GO:0001964 21 14 0,000 0,10938179 0,1584245 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,10938179 0,1583248 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,10938179 0,15822523 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,10938179 0,15812578 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,10938179 0,15802645 ! glycine metabolic process GO:0006544 22 14 0,000 0,10938179 0,15792725 ! pituitary gland development GO:0021983 23 14 0,000 0,10938179 0,15782817 ! cellular response to starvation GO:0009267 21 14 0,000 0,10938179 0,15772922 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,10938179 0,15763039 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,10938179 0,15753169 ! regulation of heart rate GO:0002027 23 14 0,000 0,10938179 0,15743311 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,10938179 0,15733465 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,10938179 0,15723632 ! embryo implantation GO:0007566 27 14 0,000 0,10938179 0,15713811 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 0,000 0,10938179 0,15704002 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,10938179 0,15694205 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,10938179 0,15684421 ! axon cargo transport GO:0008088 27 14 0,000 0,10938179 0,15674648 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,10938179 0,15664888 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,10938179 0,15655141 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,10938179 0,15645405 ! mRNA splice site selection GO:0006376 26 14 0,000 0,10938179 0,15635681 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,10938179 0,15625969 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,10938179 0,1561627 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,10938179 0,15606582 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,10938179 0,15596907 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,10938179 0,15587243 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,10938179 0,15577592 ! muscle maintenance GO:0046716 19 14 0,000 0,10938179 0,15567952 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,10938179 0,15558325 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,10938179 0,15548709 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,10938179 0,15539105 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,10938179 0,15529513 ! cell killing GO:0001906 20 14 0,000 0,10938179 0,15519933 ! cilium assembly GO:0042384 20 14 0,000 0,10938179 0,15510364 ! peptide hormone secretion GO:0030072 23 14 0,000 0,10938179 0,15500808 ! response to drug GO:0042493 108 69 1,000 0,11073552 0,15682986 ! humoral immune response GO:0006959 86 70 1,000 0,11340262 0,16050833 ! amine transport GO:0015837 101 70 1,000 0,11340262 0,16040962 ! muscle cell differentiation GO:0042692 104 71 1,000 0,11608632 0,16410481 ! positive regulation of cell size GO:0045793 20 15 0,000 0,11672373 0,16490453 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,11672373 0,1648033 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,11672373 0,16470219 ! skin development GO:0043588 25 15 0,000 0,11672373 0,16460121 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,11672373 0,16450035 ! embryonic forelimb morphogenesis GO:0035115 17 15 0,000 0,11672373 0,16439962 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,11672373 0,164299 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,11672373 0,16419852 ! bile acid metabolic process GO:0008206 22 15 0,000 0,11672373 0,16409815 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,11672373 0,16399791 ! adult walking behavior GO:0007628 25 15 0,000 0,11672373 0,16389779 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,11672373 0,16379779 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,11672373 0,16369791 ! myoblast differentiation GO:0045445 27 15 0,000 0,11672373 0,16359815 ! centrosome cycle GO:0007098 16 15 0,000 0,11672373 0,16349852 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,11672373 0,16339901 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,11672373 0,16329962 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,11672373 0,16320035 ! cerebral cortex development GO:0021987 29 15 0,000 0,11672373 0,1631012 ! response to osmotic stress GO:0006970 22 15 0,000 0,11672373 0,16300217 ! vesicle coating GO:0006901 25 15 0,000 0,11672373 0,16290326 ! DNA integration GO:0015074 22 15 0,000 0,11672373 0,16280447 ! peptide secretion GO:0002790 27 15 0,000 0,11672373 0,1627058 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,11672373 0,16260725 ! regulation of vasodilation GO:0042312 24 15 0,000 0,11672373 0,16250882 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,11672373 0,16241051 ! neuron recognition GO:0008038 22 15 0,000 0,11672373 0,16231232 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,11672373 0,16221424 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,11672373 0,16211629 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,11672373 0,16201845 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,11672373 0,16192073 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,11672373 0,16182313 ! dopamine metabolic process GO:0042417 30 15 0,000 0,11672373 0,16172565 ! organic cation transport GO:0015695 19 15 0,000 0,11672373 0,16162828 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,11672373 0,16153103 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,11672373 0,1614339 ! positive regulation of neuron apoptosis GO:0043525 29 15 0,000 0,11672373 0,16133688 ! peptide hormone processing GO:0016486 19 15 0,000 0,11672373 0,16123998 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,11672373 0,1611432 ! regulation of peptidase activity GO:0052547 106 72 1,000 0,11878615 0,16389211 ! cellular lipid catabolic process GO:0044242 105 73 1,000 0,12150168 0,16753828 ! protein secretion GO:0009306 27 16 0,000 0,12400556 0,17088843 ! hormone secretion GO:0046879 25 16 0,000 0,12400556 0,1707861 ! bone remodeling GO:0046849 24 16 0,000 0,12400556 0,1706839 ! endothelial cell migration GO:0043542 22 16 0,000 0,12400556 0,17058181 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,12400556 0,17047985 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,12400556 0,17037801 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,12400556 0,17027629 ! glial cell development GO:0021782 24 16 0,000 0,12400556 0,1701747 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,12400556 0,17007322 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,12400556 0,16997186 ! protein polyubiquitination GO:0000209 26 16 0,000 0,12400556 0,16987063 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,12400556 0,16976952 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,12400556 0,16966852 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,12400556 0,16956765 ! fructose metabolic process GO:0006000 20 16 0,000 0,12400556 0,1694669 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,12400556 0,16936626 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,12400556 0,16926575 ! protein export from nucleus GO:0006611 24 16 0,000 0,12400556 0,16916536 ! negative regulation of immune response GO:0050777 28 16 0,000 0,12400556 0,16906508 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,12400556 0,16896492 ! DNA replication initiation GO:0006270 25 16 0,000 0,12400556 0,16886488 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,12400556 0,16876496 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,12400556 0,16866516 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,12400556 0,16856548 ! diencephalon development GO:0021536 25 16 0,000 0,12400556 0,16846591 ! neural crest cell migration GO:0001755 24 16 0,000 0,12400556 0,16836646 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,12400556 0,16826713 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,12400556 0,16816792 ! steroid catabolic process GO:0006706 22 16 0,000 0,12400556 0,16806882 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,12400556 0,16796984 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,12400556 0,16787098 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,12400556 0,16777223 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,12400556 0,1676736 ! sperm-egg recognition GO:0035036 16 16 0,000 0,12400556 0,16757508 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,12400556 0,16747668 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,12400556 0,1673784 ! negative regulation of translation GO:0017148 22 16 0,000 0,12400556 0,16728023 ! cofactor biosynthetic process GO:0051188 92 75 1,000 0,12697807 0,17118967 ! response to unfolded protein GO:0006986 99 76 1,000 0,12973809 0,1748082 ! regulation of cell morphogenesis GO:0022604 140 76 1,000 0,12973809 0,17470586 ! regulation of protein transport GO:0051223 114 76 1,000 0,12973809 0,17460363 GO:0070201|regulation of establishment of protein localization, ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,13122777 0,17650519 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,13122777 0,17640204 ! negative regulation of defense response GO:0031348 19 17 0,000 0,13122777 0,176299 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,13122777 0,17619608 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,13122777 0,17609328 ! glycerol metabolic process GO:0006071 20 17 0,000 0,13122777 0,1759906 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,13122777 0,17588804 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,13122777 0,1757856 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,13122777 0,17568328 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,13122777 0,17558108 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,13122777 0,175479 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 0,000 0,13122777 0,17537704 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,13122777 0,17527519 ! forelimb morphogenesis GO:0035136 19 17 0,000 0,13122777 0,17517347 ! memory GO:0007613 25 17 0,000 0,13122777 0,17507186 ! keratinization GO:0031424 17 17 0,000 0,13122777 0,17497037 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,13122777 0,17486899 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,13122777 0,17476774 ! retinoid metabolic process GO:0001523 22 17 0,000 0,13122777 0,1746666 GO:0016101|diterpenoid metabolic process, ! DNA duplex unwinding GO:0032508 25 17 0,000 0,13122777 0,17456558 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,13122777 0,17446467 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,13122777 0,17436388 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,13122777 0,17426321 ! membrane budding GO:0006900 29 17 0,000 0,13122777 0,17416266 ! heme metabolic process GO:0042168 27 17 0,000 0,13122777 0,17406222 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,13122777 0,17396189 ! body fluid secretion GO:0007589 27 17 0,000 0,13122777 0,17386168 ! stem cell differentiation GO:0048863 36 17 0,000 0,13122777 0,17376159 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,13122777 0,17366161 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,13122777 0,17356175 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,13122777 0,173462 ! sensory perception of pain GO:0019233 23 17 0,000 0,13122777 0,17336237 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,13122777 0,17326285 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,13122777 0,17316344 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,13122777 0,17306415 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,13122777 0,17296498 ! cell-cell junction organization GO:0045216 25 17 0,000 0,13122777 0,17286591 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,13122777 0,17276696 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,13122777 0,17266812 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,13122777 0,1725694 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,13122777 0,17247079 ! regulation of DNA binding GO:0051101 119 77 1,000 0,13251209 0,17405928 ! protein ubiquitination GO:0016567 125 77 1,000 0,13251209 0,17395993 ! one-carbon metabolic process GO:0006730 110 77 1,000 0,13251209 0,1738607 ! carbohydrate biosynthetic process GO:0016051 97 77 1,000 0,13251209 0,17376157 ! cellular respiration GO:0045333 107 79 1,000 0,13810039 0,18098626 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,13839086 0,18126365 ! positive regulation of translation GO:0045727 28 18 0,000 0,13839086 0,18116048 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,13839086 0,18105743 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,13839086 0,1809545 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,13839086 0,18085169 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,13839086 0,18074899 ! cAMP metabolic process GO:0046058 33 18 0,000 0,13839086 0,18064641 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,13839086 0,18054394 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,13839086 0,18044159 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,13839086 0,18033936 ! axis specification GO:0009798 26 18 0,000 0,13839086 0,18023724 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,13839086 0,18013524 GO:0050886|endocrine process, ! pancreas development GO:0031016 26 18 0,000 0,13839086 0,18003335 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,13839086 0,17993158 ! glutamine metabolic process GO:0006541 23 18 0,000 0,13839086 0,17982993 ! response to retinoic acid GO:0032526 25 18 0,000 0,13839086 0,17972838 ! pigmentation during development GO:0048066 31 18 0,000 0,13839086 0,17962696 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,13839086 0,17952564 ! fucose metabolic process GO:0006004 26 18 0,000 0,13839086 0,17942445 ! response to fungus GO:0009620 19 18 0,000 0,13839086 0,17932336 ! peptide cross-linking GO:0018149 31 18 0,000 0,13839086 0,17922239 ! heart process GO:0003015 27 18 0,000 0,13839086 0,17912153 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,13839086 0,17902079 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,13839086 0,17892016 ! visual learning GO:0008542 35 18 0,000 0,13839086 0,17881964 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,13839086 0,17871924 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,13839086 0,17861895 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,13839086 0,17851877 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,13839086 0,1784187 ! vitamin transport GO:0051180 24 18 0,000 0,13839086 0,17831875 ! hormone transport GO:0009914 27 18 0,000 0,13839086 0,17821891 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,13839086 0,17811918 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,13839086 0,17801956 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,13839086 0,17792005 ! cell-cell recognition GO:0009988 20 18 0,000 0,13839086 0,17782065 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,13839086 0,17772137 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,13839086 0,17762219 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 0,000 0,13839086 0,17752313 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,14549528 0,18653241 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,14549528 0,1864285 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,14549528 0,18632469 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,14549528 0,18622101 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,14549528 0,18611744 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,14549528 0,18601398 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,14549528 0,18591064 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,14549528 0,18580741 ! sensory perception of taste GO:0050909 23 19 0,000 0,14549528 0,1857043 ! smooth muscle contraction GO:0006939 36 19 0,000 0,14549528 0,1856013 ! peroxisome organization GO:0007031 29 19 0,000 0,14549528 0,18549842 ! digestive system process GO:0022600 30 19 0,000 0,14549528 0,18539565 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,14549528 0,185293 ! response to vitamin A GO:0033189 26 19 0,000 0,14549528 0,18519045 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,14549528 0,18508803 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,14549528 0,18498571 ! response to starvation GO:0042594 30 19 0,000 0,14549528 0,18488351 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,14549528 0,18478142 ! plasma membrane fusion GO:0045026 23 19 0,000 0,14549528 0,18467944 ! regulation of endothelial cell migration GO:0010594 40 19 0,000 0,14549528 0,18457758 ! cytolysis GO:0019835 20 19 0,000 0,14549528 0,18447583 ! vasodilation GO:0042311 33 19 0,000 0,14549528 0,18437419 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,14549528 0,18427266 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,14549528 0,18417124 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,14549528 0,18406994 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,14549528 0,18396875 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,14549528 0,18386766 ! positive regulation of intracellular transport GO:0032388 29 19 0,000 0,14549528 0,18376669 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,14549528 0,18366583 ! sarcomere organization GO:0045214 23 19 0,000 0,14549528 0,18356509 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,14549528 0,18346445 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,14549528 0,18336392 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,14549528 0,1832635 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,14549528 0,18316319 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,14549528 0,18306299 ! protein stabilization GO:0050821 26 19 0,000 0,14549528 0,1829629 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,15254153 0,19171887 ! iron ion transport GO:0006826 37 20 0,000 0,15254153 0,19161416 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,15254153 0,19150957 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,15254153 0,19140509 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,15254153 0,19130072 ! response to vitamin GO:0033273 29 20 0,000 0,15254153 0,19119647 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,15254153 0,19109234 ! hindlimb morphogenesis GO:0035137 32 20 0,000 0,15254153 0,19098831 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,15254153 0,1908844 ! spinal cord development GO:0021510 31 20 0,000 0,15254153 0,1907806 ! chromosome condensation GO:0030261 31 20 0,000 0,15254153 0,19067692 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,15254153 0,19057334 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,15254153 0,19046988 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,15254153 0,19036654 ! DNA modification GO:0006304 28 20 0,000 0,15254153 0,1902633 ! collagen fibril organization GO:0030199 45 20 0,000 0,15254153 0,19016018 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,15254153 0,19005717 ! collagen catabolic process GO:0030574 25 20 0,000 0,15254153 0,18995426 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,15254153 0,18985148 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,15254153 0,1897488 ! alditol metabolic process GO:0019400 24 20 0,000 0,15254153 0,18964623 ! actin filament-based movement GO:0030048 34 20 0,000 0,15254153 0,18954377 ! transcription initiation GO:0006352 118 85 1,000 0,1551591 0,19269218 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,1551591 0,19258819 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,15953008 0,19790679 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,15953008 0,1978001 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,15953008 0,19769353 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,15953008 0,19758707 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,15953008 0,19748072 GO:0009799|determination of symmetry, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,15953008 0,1973745 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,15953008 0,19726838 ! vesicle docking GO:0048278 27 21 0,000 0,15953008 0,19716238 ! visual behavior GO:0007632 39 21 0,000 0,15953008 0,19705649 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,15953008 0,19695072 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,15953008 0,19684506 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,15953008 0,19673951 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,15953008 0,19663408 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 0,000 0,15953008 0,19652876 ! response to endoplasmic reticulum stress GO:0034976 25 21 0,000 0,15953008 0,19642355 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,15953008 0,19631845 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,15953008 0,19621347 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,15953008 0,1961086 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,15953008 0,19600384 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,15953008 0,19589919 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,15953008 0,19579466 ! fatty acid transport GO:0015908 30 21 0,000 0,15953008 0,19569023 ! immunoglobulin production GO:0002377 33 21 0,000 0,15953008 0,19558592 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,15953008 0,19548172 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,15953008 0,19537763 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,15953008 0,19527365 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,15953008 0,19516978 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,15953008 0,19506602 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,15953008 0,19496237 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,15953008 0,19485884 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,15953008 0,19475541 ! regulation of multi-organism process GO:0043900 32 21 0,000 0,15953008 0,19465209 ! protein processing GO:0016485 114 88 1,000 0,16383486 0,19979861 ! protein import into nucleus, translocation GO:0000060 36 22 0,000 0,16646139 0,20289412 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,16646139 0,20278666 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,16646139 0,20267931 ! viral genome replication GO:0019079 29 22 0,000 0,16646139 0,20257207 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,16646139 0,20246494 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,16646139 0,20235793 ! leukocyte adhesion GO:0007159 38 22 0,000 0,16646139 0,20225103 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,16646139 0,20214425 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,16646139 0,20203758 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,16646139 0,20193102 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 0,000 0,16646139 0,20182457 ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,16646139 0,20171823 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,16646139 0,20161201 ! lysosome organization GO:0007040 37 22 0,000 0,16646139 0,2015059 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,16646139 0,2013999 GO:0051693|actin filament capping, ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,16646139 0,20129401 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,16646139 0,20118823 ! membrane depolarization GO:0051899 35 22 0,000 0,16646139 0,20108257 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,16646139 0,20097701 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,16646139 0,20087157 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,16646139 0,20076623 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,16646139 0,20066101 ! neural tube closure GO:0001843 33 22 0,000 0,16646139 0,2005559 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,16646139 0,20045089 ! response to virus GO:0009615 122 91 1,000 0,17259518 0,20772837 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,17333594 0,20851081 ! neuron fate commitment GO:0048663 32 23 0,000 0,17333594 0,20840181 ! embryonic pattern specification GO:0009880 31 23 0,000 0,17333594 0,20829293 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,17333594 0,20818416 ! ER-nuclear signaling pathway GO:0006984 27 23 0,000 0,17333594 0,2080755 ! negative regulation of DNA replication GO:0008156 35 23 0,000 0,17333594 0,20796696 ! vesicle targeting GO:0006903 32 23 0,000 0,17333594 0,20785853 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,17333594 0,20775021 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,17333594 0,20764201 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,17333594 0,20753392 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,17333594 0,20742594 ! cell fate determination GO:0001709 45 23 0,000 0,17333594 0,20731808 ! pentose metabolic process GO:0019321 31 23 0,000 0,17333594 0,20721032 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,17333594 0,20710268 ! spermatid development GO:0007286 33 23 0,000 0,17333594 0,20699515 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,17333594 0,20688773 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,17333594 0,20678043 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,17333594 0,20667323 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,17333594 0,20656615 ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,17333594 0,20645917 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,17333594 0,20635231 ! regulation of amine transport GO:0051952 38 23 0,000 0,17333594 0,20624556 ! liver development GO:0001889 40 23 0,000 0,17333594 0,20613892 ! glycerophospholipid metabolic process GO:0006650 130 92 1,000 0,17553246 0,20864324 ! sulfur metabolic process GO:0006790 118 92 1,000 0,17553246 0,20853547 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,18015418 0,21391565 ! initiation of viral infection GO:0019059 42 24 0,000 0,18015418 0,21380527 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,18015418 0,213695 ! superoxide metabolic process GO:0006801 32 24 0,000 0,18015418 0,21358485 ! regulation of endothelial cell proliferation GO:0001936 46 24 0,000 0,18015418 0,21347481 ! fat cell differentiation GO:0045444 37 24 0,000 0,18015418 0,21336489 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,18015418 0,21325507 ! sperm motility GO:0030317 27 24 0,000 0,18015418 0,21314538 ! vacuole organization GO:0007033 39 24 0,000 0,18015418 0,21303579 ! receptor metabolic process GO:0043112 37 24 0,000 0,18015418 0,21292632 ! neural crest cell development GO:0014032 39 24 0,000 0,18015418 0,21281695 GO:0014033|neural crest cell differentiation, ! primary neural tube formation GO:0014020 35 24 0,000 0,18015418 0,21270771 ! base-excision repair GO:0006284 31 24 0,000 0,18015418 0,21259857 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,18015418 0,21248954 GO:0002708|positive regulation of lymphocyte mediated immunity, ! neurotransmitter secretion GO:0007269 32 24 0,000 0,18015418 0,21238063 ! angiogenesis GO:0001525 149 95 1,000 0,18439119 0,21726421 ! carboxylic acid transport GO:0046942 147 95 1,000 0,18439119 0,21715296 GO:0015849|organic acid transport, ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,18691657 0,22001438 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,18691657 0,21990184 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,18691657 0,21978942 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,18691657 0,21967711 GO:0006479|protein amino acid methylation, ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,18691657 0,21956492 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,18691657 0,21945284 ! peptide transport GO:0015833 43 25 0,000 0,18691657 0,21934087 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,18691657 0,21922902 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,18691657 0,21911728 ! phospholipid transport GO:0015914 35 25 0,000 0,18691657 0,21900566 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,18691657 0,21889415 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,18691657 0,21878275 ! protein maturation GO:0051604 129 96 1,000 0,18735864 0,21918864 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,19362356 0,22640274 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 0,000 0,19362356 0,2262877 ! translational initiation GO:0006413 43 26 0,000 0,19362356 0,22617278 ! regulation of pH GO:0006885 36 26 0,000 0,19362356 0,22605797 ! circadian rhythm GO:0007623 42 26 0,000 0,19362356 0,22594328 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,19362356 0,2258287 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,19362356 0,22571424 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,19362356 0,2255999 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,19362356 0,22548567 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,19362356 0,22537156 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,19362356 0,22525756 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,19362356 0,22514368 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,19362356 0,22502991 ! regulation of coagulation GO:0050818 39 26 0,000 0,19362356 0,22491626 ! regulation of translation GO:0006417 151 100 1,000 0,19929282 0,2313849 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,19929282 0,23126816 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,20027561 0,23229143 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,20027561 0,23217435 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,20027561 0,23205739 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,20027561 0,23194054 ! membrane docking GO:0022406 39 27 0,000 0,20027561 0,23182381 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,20027561 0,2317072 ! catechol metabolic process GO:0009712 43 27 0,000 0,20027561 0,23159071 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,20027561 0,23147433 ! acute-phase response GO:0006953 42 27 0,000 0,20027561 0,23135807 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,20027561 0,23124192 ! myofibril assembly GO:0030239 36 27 0,000 0,20027561 0,2311259 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,20027561 0,23100999 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,20027561 0,23089419 ! natural killer cell activation GO:0030101 35 27 0,000 0,20027561 0,23077851 ! lipid oxidation GO:0034440 38 27 0,000 0,20027561 0,23066295 GO:0019395|fatty acid oxidation, ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,20027561 0,2305475 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,20027561 0,23043217 GO:0043433|negative regulation of transcription factor activity, ! gene silencing GO:0016458 41 27 0,000 0,20027561 0,23031696 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,20687317 0,23778525 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,20687317 0,23766648 ! phenol metabolic process GO:0018958 44 28 0,000 0,20687317 0,23754782 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,20687317 0,23742929 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,20687317 0,23731087 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,20687317 0,23719257 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,20687317 0,23707438 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,20687317 0,23695632 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,20687317 0,23683837 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,20687317 0,23672054 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,20687317 0,23660283 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,20687317 0,23648523 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,20687317 0,23636775 ! mesoderm formation GO:0001707 46 28 0,000 0,20687317 0,23625039 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,20687317 0,23613315 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,20687317 0,23601602 ! neural tube formation GO:0001841 41 28 0,000 0,20687317 0,235899 ! regulation of innate immune response GO:0045088 38 29 0,000 0,21341667 0,24324001 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,21341667 0,24311953 ! protein targeting to membrane GO:0006612 53 29 0,000 0,21341667 0,24299918 ! regulation of axonogenesis GO:0050770 51 29 0,000 0,21341667 0,24287894 ! regulation of protein import into nucleus GO:0042306 53 29 0,000 0,21341667 0,24275882 ! muscle cell development GO:0055001 38 29 0,000 0,21341667 0,24263882 ! formation of primary germ layer GO:0001704 48 29 0,000 0,21341667 0,24251894 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,21341667 0,24239918 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,21990656 0,24964713 ! collagen metabolic process GO:0032963 40 30 0,000 0,21990656 0,24952397 ! organic anion transport GO:0015711 51 30 0,000 0,21990656 0,24940093 ! cholesterol transport GO:0030301 46 30 0,000 0,21990656 0,24927801 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 49 30 0,000 0,21990656 0,24915521 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,21990656 0,24903254 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,21990656 0,24890998 ! ceramide metabolic process GO:0006672 43 30 0,000 0,21990656 0,24878755 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,21990656 0,24866523 ! adult locomotory behavior GO:0008344 47 30 0,000 0,21990656 0,24854304 ! embryonic epithelial tube formation GO:0001838 44 30 0,000 0,21990656 0,24842096 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,21990656 0,24829901 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,21990656 0,24817717 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,21990656 0,24805546 ! DNA damage checkpoint GO:0000077 53 31 0,000 0,22634327 0,25519094 ! negative regulation of secretion GO:0051048 49 31 0,000 0,22634327 0,25506591 ! glial cell differentiation GO:0010001 55 31 0,000 0,22634327 0,254941 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,22634327 0,25481621 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,22634327 0,25469154 ! xenobiotic metabolic process GO:0006805 44 31 0,000 0,22634327 0,254567 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,22634327 0,25444258 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,22634327 0,25431828 ! positive regulation of gene-specific transcription GO:0043193 47 31 0,000 0,22634327 0,2541941 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,22634327 0,25407004 ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,22634327 0,2539461 ! RNA modification GO:0009451 40 31 0,000 0,22634327 0,25382229 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,23272723 0,26085411 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,23272723 0,26072705 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,23272723 0,26060011 ! monovalent inorganic cation homeostasis GO:0055067 45 32 0,000 0,23272723 0,2604733 ! cytokine production GO:0001816 44 32 0,000 0,23272723 0,26034661 ! vesicle localization GO:0051648 47 32 0,000 0,23272723 0,26022004 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,23905888 0,26716979 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,23905888 0,26704003 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,23905888 0,2669104 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,23905888 0,2667809 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,23905888 0,26665152 ! actomyosin structure organization GO:0031032 43 33 0,000 0,23905888 0,26652226 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,23905888 0,26639313 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,23905888 0,26626413 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,23905888 0,26613525 ! negative regulation of DNA binding GO:0043392 54 33 0,000 0,23905888 0,26600649 ! lipid homeostasis GO:0055088 55 33 0,000 0,23905888 0,26587787 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,23905888 0,26574936 ! regulation of proteolysis GO:0030162 50 33 0,000 0,23905888 0,26562098 ! negative regulation of hydrolase activity GO:0051346 50 33 0,000 0,23905888 0,26549272 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,23905888 0,26536459 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,23905888 0,26523658 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 0,000 0,24533864 0,27207274 ! mRNA catabolic process GO:0006402 48 34 0,000 0,24533864 0,27194162 ! regulation of neuron projection development GO:0010975 63 34 0,000 0,24533864 0,27181063 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,24533864 0,27167976 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,24533864 0,27154902 ! feeding behavior GO:0007631 45 34 0,000 0,24533864 0,27141841 ! DNA integrity checkpoint GO:0031570 57 34 0,000 0,24533864 0,27128792 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,24533864 0,27115755 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,24533864 0,27102732 ! polyol metabolic process GO:0019751 44 34 0,000 0,24533864 0,2708972 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 0,000 0,24533864 0,27076721 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,25156693 0,27750789 ! Notch signaling pathway GO:0007219 56 35 0,000 0,25156693 0,27737485 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,25156693 0,27724195 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,25156693 0,27710917 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,25156693 0,27697652 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,25156693 0,27684399 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,25156693 0,27671159 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,25156693 0,27657932 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,25156693 0,27644718 ! glycogen metabolic process GO:0005977 48 35 0,000 0,25156693 0,27631516 ! protein homooligomerization GO:0051260 52 35 0,000 0,25156693 0,27618327 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,25774417 0,28282996 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,25774417 0,28269509 ! negative regulation of binding GO:0051100 58 36 0,000 0,25774417 0,28256034 ! tissue remodeling GO:0048771 62 36 0,000 0,25774417 0,28242573 ! neural tube development GO:0021915 50 36 0,000 0,25774417 0,28229124 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,25774417 0,28215688 ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,25774417 0,28202265 ! response to xenobiotic stimulus GO:0009410 50 36 0,000 0,25774417 0,28188854 ! glucan metabolic process GO:0044042 49 36 0,000 0,25774417 0,28175456 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,26387078 0,28831487 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,26387078 0,28817797 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,26387078 0,2880412 ! ion transmembrane transport GO:0034220 56 37 0,000 0,26387078 0,28790456 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,26387078 0,28776804 ! regulation of protein secretion GO:0050708 51 37 0,000 0,26387078 0,28763166 ! amino acid activation GO:0043038 52 37 0,000 0,26387078 0,28749541 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,26387078 0,28735928 ! gliogenesis GO:0042063 71 38 0,000 0,26994717 0,29383743 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,26994717 0,29369844 ! phagocytosis GO:0006909 60 38 0,000 0,26994717 0,29355957 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,27597375 0,29997147 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,27597375 0,29982977 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,27597375 0,29968821 ! morphogenesis of embryonic epithelium GO:0016331 60 39 0,000 0,27597375 0,29954678 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,27597375 0,29940548 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,27597375 0,29926432 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,27597375 0,29912329 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,28195092 0,3054579 ! response to calcium ion GO:0051592 58 40 0,000 0,28195092 0,30531409 ! regulation of tube size GO:0035150 60 40 0,000 0,28195092 0,30517041 GO:0050880|regulation of blood vessel size, ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,28195092 0,30502687 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,28195092 0,30488346 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! double-strand break repair GO:0006302 67 40 0,000 0,28195092 0,30474019 ! epidermal cell differentiation GO:0009913 53 40 0,000 0,28195092 0,30459705 ! positive regulation of protein transport GO:0051222 55 40 0,000 0,28195092 0,30445405 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,28787909 0,31070948 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,28787909 0,31056374 ! striated muscle contraction GO:0006941 62 41 0,000 0,28787909 0,31041814 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,28787909 0,31027268 ! biopolymer methylation GO:0043414 62 41 0,000 0,28787909 0,31012735 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,29375865 0,31631315 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,29375865 0,31616513 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,29375865 0,31601725 ! excretion GO:0007588 63 42 0,000 0,29375865 0,31586951 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,29375865 0,31572191 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,29375865 0,31557445 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,29375865 0,31542712 ! neuromuscular process GO:0050905 79 43 0,000 0,29959 0,32153849 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,29959 0,32138852 ! tRNA processing GO:0008033 49 43 0,000 0,29959 0,32123869 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,29959 0,321089 ! methylation GO:0032259 64 43 0,000 0,29959 0,32093945 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,30537353 0,32698283 ! regulation of cell projection organization GO:0031344 83 44 0,000 0,30537353 0,32683068 ! regulation of ion transport GO:0043269 57 44 0,000 0,30537353 0,32667866 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,30537353 0,32652679 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,30537353 0,32637506 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,30537353 0,32622347 ! RNA catabolic process GO:0006401 64 45 0,000 0,31110964 0,33219692 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,31110964 0,33204277 ! vascular process in circulatory system GO:0003018 69 45 0,000 0,31110964 0,33188876 ! cell recognition GO:0008037 58 45 0,000 0,31110964 0,33173489 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,3167987 0,33764458 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,3167987 0,33748819 ! cell redox homeostasis GO:0045454 63 46 0,000 0,3167987 0,33733195 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,3167987 0,33717585 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,3167987 0,33701989 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,32244111 0,34286387 ! viral infectious cycle GO:0019058 71 47 0,000 0,32244111 0,34270543 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,32244111 0,34254713 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,32244111 0,34238899 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,32244111 0,34223099 ! chloride transport GO:0006821 67 48 0,000 0,32803723 0,34800998 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,32803723 0,34784953 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,32803723 0,34768923 ! gastrulation GO:0007369 73 48 0,000 0,32803723 0,34752908 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,32803723 0,34736908 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,32803723 0,34720922 ! regulation of endocytosis GO:0030100 63 48 0,000 0,32803723 0,34704951 ! nuclear export GO:0051168 69 48 0,000 0,32803723 0,34688995 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,32803723 0,34673053 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,33358746 0,35243508 ! sensory perception of smell GO:0007608 61 49 0,000 0,33358746 0,35227326 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,33358746 0,35211159 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,33358746 0,35195007 ! RNA elongation GO:0006354 62 49 0,000 0,33358746 0,3517887 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,33358746 0,35162748 ! integrin-mediated signaling pathway GO:0007229 81 49 0,000 0,33358746 0,3514664 ! regulation of actin filament length GO:0030832 72 50 0,000 0,33909216 0,35710255 ! membrane fusion GO:0006944 80 50 0,000 0,33909216 0,35693911 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,33909216 0,35677583 ! proton transport GO:0015992 75 50 0,000 0,33909216 0,3566127 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,33909216 0,35644971 ! positive regulation of secretion GO:0051047 71 51 0,000 0,3445517 0,36202326 ! hydrogen transport GO:0006818 77 51 0,000 0,3445517 0,36185795 ! adult behavior GO:0030534 80 51 0,000 0,3445517 0,36169279 ! transition metal ion transport GO:0000041 74 52 0,000 0,34996645 0,36720933 ! regulation of cellular component size GO:0032535 74 52 0,000 0,34996645 0,36704188 ! nucleotide-excision repair GO:0006289 64 52 0,000 0,34996645 0,36687459 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,34996645 0,36670744 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,35533678 0,37216512 ! single fertilization GO:0007338 59 53 0,000 0,35533678 0,37199572 ! cell projection assembly GO:0030031 76 53 0,000 0,35533678 0,37182648 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,36066305 0,37722829 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,36066305 0,37705682 ! mesoderm development GO:0007498 76 55 0,000 0,36594561 0,38240568 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,36594561 0,38223202 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,36594561 0,38205851 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,37638105 0,39277515 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,38153463 0,39797263 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,38153463 0,39779223 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,38664592 0,40293865 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,39171525 0,40803672 ! embryonic limb morphogenesis GO:0030326 86 60 0,000 0,39171525 0,407852 GO:0035113|embryonic appendage morphogenesis, ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,39171525 0,40766745 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,39171525 0,40748307 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,39171525 0,40729886 ! fertilization GO:0009566 68 60 0,000 0,39171525 0,40711481 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,39674297 0,41215395 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,39674297 0,41196787 ! extracellular matrix organization GO:0030198 103 61 0,000 0,39674297 0,41178197 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,39674297 0,41159623 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! neurotransmitter transport GO:0006836 81 62 0,000 0,40172943 0,41658146 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,40172943 0,41639373 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,40172943 0,41620616 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,40667495 0,4211402 ! appendage morphogenesis GO:0035107 93 64 0,000 0,41157987 0,42602777 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,41157987 0,42583612 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,41157987 0,42564465 ! adaptive immune response GO:0002250 94 64 0,000 0,41157987 0,42545335 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! appendage development GO:0048736 94 65 0,000 0,41644452 0,43028859 GO:0060173|limb development, ! defense response to bacterium GO:0042742 73 65 0,000 0,41644452 0,43009537 ! activation of immune response GO:0002253 83 65 0,000 0,41644452 0,42990233 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,42126923 0,43468785 ! antigen processing and presentation GO:0019882 96 66 0,000 0,42126923 0,43449293 ! regulation of immune effector process GO:0002697 101 66 0,000 0,42126923 0,43429817 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,42605433 0,43903448 ! acute inflammatory response GO:0002526 92 68 0,000 0,43080013 0,44372606 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,43080013 0,44352744 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,43080013 0,44332899 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,43080013 0,44313072 ! inorganic anion transport GO:0015698 93 68 0,000 0,43080013 0,44293263 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,43550696 0,44757194 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,44017514 0,45216741 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,44480498 0,4567194 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,44480498 0,4565156 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,4493968 0,46102258 ! regulation of blood pressure GO:0008217 107 73 0,000 0,45395089 0,46548687 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,45846759 0,46990884 ! digestion GO:0007586 97 74 0,000 0,45846759 0,46969953 ! protein import into nucleus GO:0006606 118 74 0,000 0,45846759 0,4694904 ! blood coagulation GO:0007596 116 75 0,000 0,46294717 0,47386671 GO:0050817|coagulation, ! nuclear import GO:0051170 121 75 0,000 0,46294717 0,47365592 ! amine biosynthetic process GO:0009309 97 76 0,000 0,46738996 0,47798884 ! tRNA metabolic process GO:0006399 95 76 0,000 0,46738996 0,4777764 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,47179625 0,48206636 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,47179625 0,4818523 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,47179625 0,48163843 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,47616633 0,48588401 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,48050051 0,49008922 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,48050051 0,48987198 ! regulation of lyase activity GO:0051339 133 79 0,000 0,48050051 0,48965493 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,48050051 0,48943808 ! chromatin assembly GO:0031497 102 80 0,000 0,48479908 0,493598 GO:0006334|nucleosome assembly, ! protein localization in nucleus GO:0034504 133 80 0,000 0,48479908 0,49337959 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,48479908 0,49316138 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,48906232 0,49727822 ! hemostasis GO:0007599 125 81 0,000 0,48906232 0,49705848 ! mRNA transport GO:0051028 121 81 0,000 0,48906232 0,49683893 ! regulation of neurological system process GO:0031644 122 81 0,000 0,48906232 0,49661957 ! vitamin metabolic process GO:0006766 103 81 0,000 0,48906232 0,49640041 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,49748398 0,5047257 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,49748398 0,50450316 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,50164298 0,50849663 ! sterol metabolic process GO:0016125 120 84 0,000 0,50164298 0,50827262 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,50576778 0,51222629 ! rRNA metabolic process GO:0016072 107 85 0,000 0,50576778 0,51200084 GO:0006364|rRNA processing, ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,50985869 0,51591508 ! nucleosome organization GO:0034728 114 87 0,000 0,51391596 0,51979187 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,51391596 0,51956339 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,51391596 0,51933511 ! Wnt receptor signaling pathway GO:0016055 130 87 0,000 0,51391596 0,51910703 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,51793988 0,52294194 ! establishment of RNA localization GO:0051236 128 88 0,000 0,51793988 0,52271248 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,52193072 0,52650906 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,52193072 0,52627824 ! hormone metabolic process GO:0042445 121 90 0,000 0,52588875 0,53003686 ! RNA localization GO:0006403 135 91 0,000 0,52981423 0,53375941 ! ATP metabolic process GO:0046034 137 91 0,000 0,52981423 0,53352572 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,53370744 0,53721099 ! positive regulation of immune response GO:0050778 121 92 0,000 0,53370744 0,53697599 ! DNA recombination GO:0006310 146 92 0,000 0,53370744 0,5367412 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,53756863 0,54038805 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,53756863 0,54015197 ! electron transport chain GO:0022900 123 94 0,000 0,54139807 0,54376226 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,54896273 0,55111928 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,54896273 0,55087883 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,55269845 0,55438572 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,56007798 0,56154287 ! protein import GO:0017038 156 99 0,000 0,56007798 0,56129819 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,56372227 0,56470437 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,56372227 0,56445852 ! divalent metal ion transport GO:0070838 171 100 0,000 0,56372227 0,56421289 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,56372227 0,56396747 ! protein localization in organelle GO:0033365 161 100 0,000 0,56372227 0,56372227