pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6422-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! interphase of mitotic cell cycle GO:0051329 209 95 8,000 1,105E-08 2,658E-05 ! interphase GO:0051325 213 98 8,000 1,455E-08 1,751E-05 ! cartilage development GO:0051216 90 52 6,000 4,172E-08 3,346E-05 ! negative regulation of protein kinase activity GO:0006469 130 67 6,000 2,501E-07 1,504E-04 ! negative regulation of kinase activity GO:0033673 131 68 6,000 2,773E-07 1,334E-04 ! regulation of epithelial cell proliferation GO:0050678 111 43 5,000 3,207E-07 1,286E-04 ! negative regulation of phosphorylation GO:0042326 47 24 4,000 3,95E-07 1,358E-04 ! negative regulation of transferase activity GO:0051348 140 72 6,000 4,123E-07 1,24E-04 ! induction of apoptosis by intracellular signals GO:0008629 93 45 5,000 4,239E-07 1,133E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 5,000 4,849E-07 1,167E-04 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 4,000 4,912E-07 1,074E-04 ! chondrocyte differentiation GO:0002062 24 11 3,000 5,208E-07 1,044E-04 ! thymus development GO:0048538 27 11 3,000 5,208E-07 9,64E-05 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 4,000 6,05E-07 1,04E-04 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 5,000 1,772E-06 2,842E-04 ! peptidyl-threonine phosphorylation GO:0018107 20 5 2,000 2,567E-06 3,86E-04 ! cell cycle arrest GO:0007050 213 100 6,000 3,853E-06 5,453E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 5,000 4,62E-06 6,176E-04 ! neural nucleus development GO:0048857 14 6 2,000 5,109E-06 6,47E-04 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 3,000 5,877E-06 7,069E-04 ! positive regulation of protein ubiquitination GO:0031398 12 7 2,000 8,899E-06 1,02E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 2,000 8,899E-06 9,732E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 2,000 8,899E-06 9,309E-04 ! peptidyl-threonine modification GO:0018210 25 7 2,000 8,899E-06 8,921E-04 ! glycolysis GO:0006096 65 45 4,000 1,018E-05 9,798E-04 ! cell growth GO:0016049 84 45 4,000 1,018E-05 9,421E-04 ! positive regulation of phosphorylation GO:0042327 129 79 5,000 1,208E-05 1,076E-03 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 5,000 1,395E-05 1,199E-03 GO:0045937|positive regulation of phosphate metabolic process, ! regulation of T cell differentiation in the thymus GO:0033081 13 8 2,000 1,417E-05 1,176E-03 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 1,417E-05 1,136E-03 ! dendrite morphogenesis GO:0048813 13 8 2,000 1,417E-05 1,1E-03 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 3,000 1,861E-05 1,399E-03 ! vasculogenesis GO:0001570 46 25 3,000 1,861E-05 1,357E-03 ! axon extension GO:0048675 15 9 2,000 2,116E-05 1,497E-03 ! induction of positive chemotaxis GO:0050930 15 9 2,000 2,116E-05 1,454E-03 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 2,000 2,116E-05 1,414E-03 ! regulation of telomere maintenance GO:0032204 14 9 2,000 2,116E-05 1,376E-03 ! insulin receptor signaling pathway GO:0008286 64 26 3,000 2,188E-05 1,386E-03 ! regulation of chromosome organization GO:0033044 42 27 3,000 2,556E-05 1,577E-03 ! glucose catabolic process GO:0006007 82 55 4,000 2,752E-05 1,655E-03 ! central nervous system neuron axonogenesis GO:0021955 22 10 2,000 3,008E-05 1,765E-03 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of gliogenesis GO:0014013 23 10 2,000 3,008E-05 1,723E-03 GO:0045685|regulation of glial cell differentiation, ! regulation of insulin receptor signaling pathway GO:0046626 19 10 2,000 3,008E-05 1,683E-03 ! protein sumoylation GO:0016925 15 10 2,000 3,008E-05 1,645E-03 ! positive regulation of cell migration GO:0030335 126 57 4,000 3,279E-05 1,753E-03 ! forebrain development GO:0030900 188 95 5,000 3,469E-05 1,814E-03 ! skeletal system morphogenesis GO:0048705 105 59 4,000 3,88E-05 1,986E-03 ! peptide or protein amino-terminal blocking GO:0018409 21 11 2,000 4,116E-05 2,063E-03 ! negative regulation of glucose import GO:0046325 17 11 2,000 4,116E-05 2,021E-03 GO:0010829|negative regulation of glucose transport, ! regulation of embryonic development GO:0045995 27 11 2,000 4,116E-05 1,981E-03 ! response to peptide hormone stimulus GO:0043434 122 61 4,000 4,563E-05 2,152E-03 ! ear development GO:0043583 103 62 4,000 4,937E-05 2,284E-03 ! regulation of homeostatic process GO:0032844 134 62 4,000 4,937E-05 2,241E-03 ! spindle organization GO:0007051 46 32 3,000 5,108E-05 2,276E-03 ! metanephros development GO:0001656 74 32 3,000 5,108E-05 2,234E-03 ! negative regulation of MAP kinase activity GO:0043407 69 32 3,000 5,108E-05 2,195E-03 ! regulation of positive chemotaxis GO:0050926 19 12 2,000 5,463E-05 2,306E-03 GO:0050927|positive regulation of positive chemotaxis, ! focal adhesion formation GO:0048041 35 12 2,000 5,463E-05 2,266E-03 ! histone acetylation GO:0016573 26 12 2,000 5,463E-05 2,228E-03 ! peptidyl-lysine modification GO:0018205 21 12 2,000 5,463E-05 2,191E-03 ! T cell homeostasis GO:0043029 25 12 2,000 5,463E-05 2,155E-03 ! positive regulation of cell motion GO:0051272 146 64 4,000 5,757E-05 2,234E-03 ! hexose catabolic process GO:0019320 104 67 4,000 7,18E-05 2,742E-03 ! embryonic skeletal system morphogenesis GO:0048704 59 35 3,000 7,327E-05 2,754E-03 ! urogenital system development GO:0001655 137 69 4,000 8,27E-05 3,061E-03 ! N-terminal protein amino acid modification GO:0031365 27 14 2,000 8,953E-05 3,264E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 2,000 8,953E-05 3,215E-03 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 2,000 8,953E-05 3,168E-03 GO:0060675|ureteric bud morphogenesis, ! release of cytochrome c from mitochondria GO:0001836 30 14 2,000 8,953E-05 3,122E-03 ! cellular response to insulin stimulus GO:0032869 82 37 3,000 9,15E-05 3,145E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 4,000 1,014E-04 3,435E-03 ! regulation of the force of heart contraction GO:0002026 26 15 2,000 1,114E-04 3,722E-03 ! lymphocyte homeostasis GO:0002260 30 15 2,000 1,114E-04 3,671E-03 ! monosaccharide catabolic process GO:0046365 115 76 4,000 1,311E-04 4,263E-03 ! regulation of protein ubiquitination GO:0031396 25 16 2,000 1,364E-04 4,377E-03 ! regulation of T cell differentiation GO:0045580 70 41 3,000 1,375E-04 4,353E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,649E-04 5,153E-03 ! neutrophil chemotaxis GO:0030593 27 17 2,000 1,649E-04 5,087E-03 ! negative regulation of homeostatic process GO:0032845 33 17 2,000 1,649E-04 5,022E-03 ! cell-substrate junction assembly GO:0007044 54 18 2,000 1,969E-04 5,923E-03 ! peptidyl-serine phosphorylation GO:0018105 38 18 2,000 1,969E-04 5,85E-03 ! branching morphogenesis of a tube GO:0048754 97 45 3,000 1,983E-04 5,819E-03 ! pigmentation GO:0043473 100 46 3,000 2,161E-04 6,265E-03 ! response to insulin stimulus GO:0032868 95 46 3,000 2,161E-04 6,19E-03 ! cellular pigmentation GO:0033059 36 19 2,000 2,328E-04 6,589E-03 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 2,000 2,328E-04 6,512E-03 ! alcohol catabolic process GO:0046164 130 86 4,000 2,347E-04 6,491E-03 ! regulation of lymphocyte differentiation GO:0045619 81 48 3,000 2,551E-04 6,976E-03 ! positive regulation of protein modification process GO:0031401 136 88 4,000 2,613E-04 7,064E-03 ! gland development GO:0048732 206 88 4,000 2,613E-04 6,986E-03 ! positive regulation of ossification GO:0045778 47 20 2,000 2,726E-04 7,206E-03 ! protein amino acid acetylation GO:0006473 39 20 2,000 2,726E-04 7,128E-03 ! response to alkaloid GO:0043279 38 20 2,000 2,726E-04 7,051E-03 ! apoptotic mitochondrial changes GO:0008637 41 20 2,000 2,726E-04 6,976E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 2,726E-04 6,903E-03 ! peptidyl-serine modification GO:0018209 43 20 2,000 2,726E-04 6,831E-03 ! regulation of glucose import GO:0046324 29 20 2,000 2,726E-04 6,761E-03 GO:0010827|regulation of glucose transport, ! inner ear receptor cell differentiation GO:0060113 37 20 2,000 2,726E-04 6,692E-03 ! ossification GO:0001503 188 90 4,000 2,901E-04 7,051E-03 ! regulation of ossification GO:0030278 117 50 3,000 2,99E-04 7,193E-03 ! bone development GO:0060348 189 91 4,000 3,054E-04 7,276E-03 ! inactivation of MAPK activity GO:0000188 39 21 2,000 3,165E-04 7,466E-03 ! positive regulation of locomotion GO:0040017 39 21 2,000 3,165E-04 7,393E-03 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of inflammatory response GO:0050729 35 21 2,000 3,165E-04 7,322E-03 ! positive regulation of osteoblast differentiation GO:0045669 49 21 2,000 3,165E-04 7,252E-03 ! embryonic skeletal system development GO:0048706 85 51 3,000 3,228E-04 7,327E-03 ! regulation of muscle contraction GO:0006937 81 52 3,000 3,48E-04 7,824E-03 ! morphogenesis of a branching structure GO:0001763 111 52 3,000 3,48E-04 7,752E-03 ! positive regulation of bone remodeling GO:0046852 51 22 2,000 3,647E-04 8,051E-03 GO:0034105|positive regulation of tissue remodeling, ! regulation of chemotaxis GO:0050920 40 22 2,000 3,647E-04 7,978E-03 ! mechanoreceptor differentiation GO:0042490 40 22 2,000 3,647E-04 7,906E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 3,647E-04 7,835E-03 ! central nervous system neuron development GO:0021954 46 22 2,000 3,647E-04 7,766E-03 ! ureteric bud development GO:0001657 43 22 2,000 3,647E-04 7,698E-03 ! response to glucocorticoid stimulus GO:0051384 38 22 2,000 3,647E-04 7,631E-03 ! response to UV GO:0009411 104 53 3,000 3,745E-04 7,768E-03 ! embryonic camera-type eye development GO:0031076 10 5 1,000 4,034E-04 8,295E-03 GO:0048596|embryonic camera-type eye morphogenesis, ! regulation of mitochondrial membrane permeability GO:0046902 14 5 1,000 4,034E-04 8,225E-03 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 1,000 4,034E-04 8,156E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 4,034E-04 8,088E-03 ! parathyroid gland development GO:0060017 13 5 1,000 4,034E-04 8,021E-03 ! negative regulation of survival gene product expression GO:0008634 8 5 1,000 4,034E-04 7,956E-03 ! morphogenesis of an epithelial sheet GO:0002011 11 5 1,000 4,034E-04 7,891E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 4,034E-04 7,827E-03 ! homeostasis of number of cells within a tissue GO:0048873 12 5 1,000 4,034E-04 7,765E-03 ! meiotic chromosome segregation GO:0045132 7 5 1,000 4,034E-04 7,703E-03 ! decidualization GO:0046697 11 5 1,000 4,034E-04 7,642E-03 ! B cell homeostasis GO:0001782 13 5 1,000 4,034E-04 7,583E-03 ! cellular response to nutrient GO:0031670 8 5 1,000 4,034E-04 7,524E-03 ! regulation of mitochondrial depolarization GO:0051900 13 5 1,000 4,034E-04 7,466E-03 ! hemopoietic progenitor cell differentiation GO:0002244 14 5 1,000 4,034E-04 7,409E-03 ! activation of pro-apoptotic gene products GO:0008633 47 23 2,000 4,175E-04 7,609E-03 ! sex determination GO:0007530 47 23 2,000 4,175E-04 7,552E-03 ! central nervous system neuron differentiation GO:0021953 50 24 2,000 4,749E-04 8,526E-03 ! response to corticosteroid stimulus GO:0031960 41 24 2,000 4,749E-04 8,463E-03 ! regulation of behavior GO:0050795 43 24 2,000 4,749E-04 8,401E-03 ! regulation of oxidoreductase activity GO:0051341 46 24 2,000 4,749E-04 8,34E-03 ! leukocyte homeostasis GO:0001776 44 24 2,000 4,749E-04 8,279E-03 ! regulation of bone remodeling GO:0046850 137 57 3,000 4,952E-04 8,572E-03 ! regulation of tissue remodeling GO:0034103 140 58 3,000 5,293E-04 9,096E-03 ! regulation of heart contraction GO:0008016 110 60 3,000 6,023E-04 0,01027699 ! protein amino acid autophosphorylation GO:0046777 141 60 3,000 6,023E-04 0,01020461 ! kidney development GO:0001822 122 60 3,000 6,023E-04 0,01013325 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 1,000 6,025E-04 0,01006743 ! embryonic hemopoiesis GO:0035162 14 6 1,000 6,025E-04 9,998E-03 ! regulation of smooth muscle cell differentiation GO:0051150 9 6 1,000 6,025E-04 9,93E-03 ! activation of MAPKKK activity GO:0000185 12 6 1,000 6,025E-04 9,862E-03 ! glutamate catabolic process GO:0006538 10 6 1,000 6,025E-04 9,795E-03 ! male sex determination GO:0030238 15 6 1,000 6,025E-04 9,73E-03 ! establishment of spindle localization GO:0051293 12 6 1,000 6,025E-04 9,665E-03 GO:0051653|spindle localization, ! negative regulation of gliogenesis GO:0014014 18 6 1,000 6,025E-04 9,601E-03 GO:0045686|negative regulation of glial cell differentiation, ! enucleate erythrocyte differentiation GO:0043353 12 6 1,000 6,025E-04 9,538E-03 ! regulation of myeloid cell apoptosis GO:0033032 13 6 1,000 6,025E-04 9,475E-03 ! myeloid dendritic cell activation GO:0001773 10 6 1,000 6,025E-04 9,414E-03 GO:0043011|myeloid dendritic cell differentiation, ! triglyceride catabolic process GO:0019433 10 6 1,000 6,025E-04 9,353E-03 ! maternal placenta development GO:0001893 12 6 1,000 6,025E-04 9,293E-03 ! pyruvate metabolic process GO:0006090 38 26 2,000 6,043E-04 9,261E-03 ! acetyl-CoA metabolic process GO:0006084 39 26 2,000 6,043E-04 9,202E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 2,000 6,043E-04 9,144E-03 ! regulation of osteoblast differentiation GO:0045667 65 26 2,000 6,043E-04 9,087E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 2,000 6,766E-04 0,01011169 ! protein amino acid acylation GO:0043543 55 27 2,000 6,766E-04 0,01004927 ! male gonad development GO:0008584 44 27 2,000 6,766E-04 9,988E-03 ! dendrite development GO:0016358 59 28 2,000 7,543E-04 0,01106568 ! negative regulation of protein modification process GO:0031400 60 28 2,000 7,543E-04 0,01099862 ! peptidyl-tyrosine modification GO:0018212 50 28 2,000 7,543E-04 0,01093236 ! cellular iron ion homeostasis GO:0006879 51 29 2,000 8,373E-04 0,01206384 ! response to organic cyclic substance GO:0014070 55 29 2,000 8,373E-04 0,01199203 ! cellular response to extracellular stimulus GO:0031668 48 29 2,000 8,373E-04 0,01192107 ! tissue homeostasis GO:0001894 48 29 2,000 8,373E-04 0,01185095 GO:0048871|multicellular organismal homeostasis, ! prostate gland development GO:0030850 13 7 1,000 8,4E-04 0,01181889 ! regulation of lipid kinase activity GO:0043550 13 7 1,000 8,4E-04 0,01175018 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 8,4E-04 0,01168226 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 1,000 8,4E-04 0,01161512 ! regulation of odontogenesis GO:0042481 13 7 1,000 8,4E-04 0,01154874 ! protein-cofactor linkage GO:0018065 13 7 1,000 8,4E-04 0,01148313 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 1,000 8,4E-04 0,01141825 ! glycerol ether catabolic process GO:0044269 12 7 1,000 8,4E-04 0,0113541 GO:0046464|acylglycerol catabolic process, ! organ growth GO:0035265 15 7 1,000 8,4E-04 0,01129067 ! B cell lineage commitment GO:0002326 21 7 1,000 8,4E-04 0,01122795 ! cranial nerve morphogenesis GO:0021602 11 7 1,000 8,4E-04 0,01116591 ! T cell lineage commitment GO:0002360 16 7 1,000 8,4E-04 0,01110456 ! regulation of respiratory burst GO:0060263 11 7 1,000 8,4E-04 0,01104388 ! regulation of protein homodimerization activity GO:0043496 18 7 1,000 8,4E-04 0,01098386 ! negative regulation of telomere maintenance GO:0032205 11 7 1,000 8,4E-04 0,01092449 ! negative regulation of cell growth GO:0030308 132 67 3,000 9,142E-04 0,01182625 ! homeostasis of number of cells GO:0048872 114 67 3,000 9,142E-04 0,01176301 ! cell junction assembly GO:0034329 78 30 2,000 9,26E-04 0,01185107 ! response to heat GO:0009408 50 30 2,000 9,26E-04 0,01178836 ! iron ion homeostasis GO:0055072 54 31 2,000 1,02E-03 0,01292177 ! negative regulation of cell size GO:0045792 134 69 3,000 1,021E-03 0,01286092 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 3,000 1,021E-03 0,01279394 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,115E-03 0,01390333 ! neutral lipid catabolic process GO:0046461 13 8 1,000 1,115E-03 0,01383166 ! succinate metabolic process GO:0006105 14 8 1,000 1,115E-03 0,01376073 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 1,000 1,115E-03 0,01369052 ! glycerolipid catabolic process GO:0046503 13 8 1,000 1,115E-03 0,01362103 ! pigment granule organization GO:0048753 16 8 1,000 1,115E-03 0,01355223 ! L-phenylalanine metabolic process GO:0006558 11 8 1,000 1,115E-03 0,01348413 GO:0006559|L-phenylalanine catabolic process, ! regulation of pigmentation during development GO:0048070 24 8 1,000 1,115E-03 0,01341671 ! melanin metabolic process GO:0006582 15 8 1,000 1,115E-03 0,01334996 ! embryonic eye morphogenesis GO:0048048 14 8 1,000 1,115E-03 0,01328387 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 1,115E-03 0,01321843 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 1,000 1,115E-03 0,01315364 ! response to UV-B GO:0010224 16 8 1,000 1,115E-03 0,01308947 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 1,000 1,115E-03 0,01302593 ! trophectodermal cell differentiation GO:0001829 13 8 1,000 1,115E-03 0,01296301 ! hindbrain development GO:0030902 61 32 2,000 1,121E-03 0,01296347 ! positive regulation of catabolic process GO:0009896 64 32 2,000 1,121E-03 0,01290144 ! reproductive structure development GO:0048608 113 71 3,000 1,136E-03 0,01301687 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 3,000 1,197E-03 0,01364925 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 3,000 1,197E-03 0,01358487 ! leukocyte chemotaxis GO:0030595 50 33 2,000 1,227E-03 0,01385975 GO:0060326|cell chemotaxis, ! meiosis GO:0007126 121 74 3,000 1,326E-03 0,01490288 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 163 75 3,000 1,393E-03 0,01559164 ! meiotic cell cycle GO:0051321 122 75 3,000 1,393E-03 0,01551945 ! middle ear morphogenesis GO:0042474 14 9 1,000 1,428E-03 0,01583165 ! T cell selection GO:0045058 23 9 1,000 1,428E-03 0,01575903 ! behavioral fear response GO:0001662 22 9 1,000 1,428E-03 0,01568707 GO:0002209|behavioral defense response, ! motor axon guidance GO:0008045 16 9 1,000 1,428E-03 0,01561576 ! protein heterooligomerization GO:0051291 16 9 1,000 1,428E-03 0,01554511 ! regulation of developmental growth GO:0048638 15 9 1,000 1,428E-03 0,01547508 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 1,428E-03 0,01540569 ! regulation of epithelial cell differentiation GO:0030856 14 9 1,000 1,428E-03 0,01533691 ! regulation of glycolysis GO:0006110 21 9 1,000 1,428E-03 0,01526875 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 1,428E-03 0,01520119 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 1,000 1,428E-03 0,01513422 ! alpha-beta T cell differentiation GO:0046632 21 9 1,000 1,428E-03 0,01506784 ! regulation of mitochondrial membrane potential GO:0051881 17 9 1,000 1,428E-03 0,01500204 ! induction of an organ GO:0001759 14 9 1,000 1,428E-03 0,01493682 ! S phase GO:0051320 9 9 1,000 1,428E-03 0,01487216 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 1,000 1,428E-03 0,01480805 ! regulation of macrophage differentiation GO:0045649 15 9 1,000 1,428E-03 0,0147445 ! positive regulation of ligase activity GO:0051351 124 77 3,000 1,536E-03 0,01579251 ! cell junction organization GO:0034330 86 36 2,000 1,583E-03 0,01620944 ! positive regulation of cell development GO:0010720 80 36 2,000 1,583E-03 0,01614075 ! embryonic organ development GO:0048568 57 36 2,000 1,583E-03 0,01607265 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 3,000 1,688E-03 0,01706901 ! meiosis I GO:0007127 65 37 2,000 1,715E-03 0,01726319 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 1,777E-03 0,01781768 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 1,777E-03 0,01774374 ! regulation of smooth muscle cell migration GO:0014910 27 10 1,000 1,777E-03 0,01767042 ! B cell proliferation GO:0042100 18 10 1,000 1,777E-03 0,01759771 ! neurotransmitter biosynthetic process GO:0042136 16 10 1,000 1,777E-03 0,01752558 ! regulation of smoothened signaling pathway GO:0008589 23 10 1,000 1,777E-03 0,01745405 ! alpha-beta T cell activation GO:0046631 23 10 1,000 1,777E-03 0,0173831 ! apical protein localization GO:0045176 15 10 1,000 1,777E-03 0,01731272 ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 1,777E-03 0,01724291 GO:0043470|regulation of carbohydrate catabolic process, ! oocyte development GO:0048599 17 10 1,000 1,777E-03 0,01717366 ! blastocyst formation GO:0001825 17 10 1,000 1,777E-03 0,01710497 ! response to nicotine GO:0035094 20 10 1,000 1,777E-03 0,01703682 ! localization within membrane GO:0051668 20 10 1,000 1,777E-03 0,01696922 ! cell-substrate adhesion GO:0031589 171 81 3,000 1,851E-03 0,01760463 ! response to nutrient GO:0007584 125 82 3,000 1,936E-03 0,01834338 ! cellular response to hormone stimulus GO:0032870 167 82 3,000 1,936E-03 0,01827144 ! development of primary male sexual characteristics GO:0046546 66 39 2,000 1,998E-03 0,01877928 ! negative regulation of transport GO:0051051 153 84 3,000 2,115E-03 0,01980224 ! negative regulation of growth GO:0045926 155 84 3,000 2,115E-03 0,01972549 ! regulation of ligase activity GO:0051340 142 84 3,000 2,115E-03 0,01964933 ! mesenchymal cell development GO:0014031 87 40 2,000 2,15E-03 0,01989601 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 2,163E-03 0,01994065 ! detection of mechanical stimulus GO:0050982 22 11 1,000 2,163E-03 0,01986454 ! telomere maintenance via telomerase GO:0007004 21 11 1,000 2,163E-03 0,01978901 GO:0010833|telomere maintenance via telomere lengthening, ! negative regulation of ossification GO:0030279 26 11 1,000 2,163E-03 0,01971405 ! neuroblast proliferation GO:0007405 24 11 1,000 2,163E-03 0,01963966 ! oocyte differentiation GO:0009994 18 11 1,000 2,163E-03 0,01956582 ! cardiac cell differentiation GO:0035051 31 11 1,000 2,163E-03 0,01949254 ! developmental induction GO:0031128 19 11 1,000 2,163E-03 0,01941981 GO:0045168|cell-cell signaling involved in cell fate specification, ! sequestering of metal ion GO:0051238 14 11 1,000 2,163E-03 0,01934762 ! tube morphogenesis GO:0035239 176 86 3,000 2,305E-03 0,02053988 ! T cell differentiation GO:0030217 81 41 2,000 2,309E-03 0,02049901 ! response to reactive oxygen species GO:0000302 67 42 2,000 2,475E-03 0,0218918 ! neuron migration GO:0001764 79 42 2,000 2,475E-03 0,02181161 ! regulation of myeloid cell differentiation GO:0045637 98 42 2,000 2,475E-03 0,021732 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 2,585E-03 0,022615 ! virus-host interaction GO:0019048 29 12 1,000 2,585E-03 0,02253306 ! regulation of B cell proliferation GO:0030888 20 12 1,000 2,585E-03 0,02245171 ! hippocampus development GO:0021766 26 12 1,000 2,585E-03 0,02237095 ! tyrosine metabolic process GO:0006570 16 12 1,000 2,585E-03 0,02229077 ! mitotic spindle organization GO:0007052 21 12 1,000 2,585E-03 0,02221116 ! asymmetric protein localization GO:0008105 20 12 1,000 2,585E-03 0,02213212 ! fear response GO:0042596 26 12 1,000 2,585E-03 0,02205363 ! cranial nerve development GO:0021545 20 12 1,000 2,585E-03 0,02197571 ! autonomic nervous system development GO:0048483 24 12 1,000 2,585E-03 0,02189833 ! gland morphogenesis GO:0022612 29 12 1,000 2,585E-03 0,02182149 ! aromatic amino acid family catabolic process GO:0009074 18 12 1,000 2,585E-03 0,02174519 ! spleen development GO:0048536 22 12 1,000 2,585E-03 0,02166942 ! digestive tract morphogenesis GO:0048546 26 12 1,000 2,585E-03 0,02159418 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 2,585E-03 0,02151946 GO:0042130|negative regulation of T cell proliferation, ! regulation of cell adhesion GO:0030155 212 89 3,000 2,611E-03 0,0216634 ! positive regulation of response to external stimulus GO:0032103 77 43 2,000 2,648E-03 0,02189424 ! sex differentiation GO:0007548 145 90 3,000 2,719E-03 0,02240452 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 2,000 2,829E-03 0,02322676 ! male sex differentiation GO:0046661 76 44 2,000 2,829E-03 0,02314776 ! JAK-STAT cascade GO:0007259 71 44 2,000 2,829E-03 0,02306929 ! leukocyte migration GO:0050900 68 45 2,000 3,016E-03 0,02451845 ! detection of stimulus involved in sensory perception GO:0050906 66 45 2,000 3,016E-03 0,02443589 ! regulation of skeletal muscle fiber development GO:0048742 32 13 1,000 3,042E-03 0,02456025 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 3,042E-03 0,02447811 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of mitotic cell cycle GO:0045930 33 13 1,000 3,042E-03 0,02439652 ! RNA-dependent DNA replication GO:0006278 23 13 1,000 3,042E-03 0,02431547 ! regulation of monooxygenase activity GO:0032768 33 13 1,000 3,042E-03 0,02423495 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 1,000 3,042E-03 0,02415497 ! embryonic placenta development GO:0001892 23 13 1,000 3,042E-03 0,02407551 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 3,061E-03 0,02414857 ! regulation of membrane potential GO:0042391 164 93 3,000 3,061E-03 0,02406965 ! regulation of T cell activation GO:0050863 158 94 3,000 3,182E-03 0,02493389 ! regulation of gene-specific transcription GO:0032583 96 46 2,000 3,212E-03 0,02508934 ! regulation of Rho protein signal transduction GO:0035023 213 95 3,000 3,305E-03 0,02573382 ! positive regulation of defense response GO:0031349 76 47 2,000 3,415E-03 0,02650269 ! endosome transport GO:0016197 108 47 2,000 3,415E-03 0,02641747 ! JNK cascade GO:0007254 91 47 2,000 3,415E-03 0,0263328 ! leukocyte differentiation GO:0002521 202 96 3,000 3,432E-03 0,02637877 ! hair follicle morphogenesis GO:0031069 26 14 1,000 3,534E-03 0,02707923 ! palate development GO:0060021 31 14 1,000 3,534E-03 0,02699327 ! regulation of mRNA processing GO:0050684 24 14 1,000 3,534E-03 0,02690785 ! bone mineralization GO:0030282 17 14 1,000 3,534E-03 0,02682296 ! T cell differentiation in the thymus GO:0033077 31 14 1,000 3,534E-03 0,02673861 ! response to gamma radiation GO:0010332 28 14 1,000 3,534E-03 0,02665479 ! positive regulation of bone mineralization GO:0030501 29 14 1,000 3,534E-03 0,0265715 ! regulation of erythrocyte differentiation GO:0045646 44 14 1,000 3,534E-03 0,02648872 ! regulation of DNA metabolic process GO:0051052 178 97 3,000 3,562E-03 0,02661245 ! positive regulation of cell cycle GO:0045787 89 48 2,000 3,625E-03 0,02700505 ! regulation of inflammatory response GO:0050727 75 48 2,000 3,625E-03 0,0269217 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 3,625E-03 0,02683887 ! regulation of action potential GO:0001508 95 49 2,000 3,844E-03 0,02836847 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 2,000 3,844E-03 0,02828172 ! induction of apoptosis by extracellular signals GO:0008624 89 49 2,000 3,844E-03 0,0281955 ! response to temperature stimulus GO:0009266 76 49 2,000 3,844E-03 0,0281098 ! detection of abiotic stimulus GO:0009582 74 49 2,000 3,844E-03 0,02802461 ! regulation of skeletal muscle tissue development GO:0048641 35 15 1,000 4,061E-03 0,02951597 ! negative regulation of bone remodeling GO:0046851 33 15 1,000 4,061E-03 0,02942706 ! heterophilic cell adhesion GO:0007157 39 15 1,000 4,061E-03 0,02933869 ! G1/S transition checkpoint GO:0031575 40 15 1,000 4,061E-03 0,02925085 ! positive regulation of biomineral formation GO:0070169 30 15 1,000 4,061E-03 0,02916354 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 4,061E-03 0,02907674 ! epithelial to mesenchymal transition GO:0001837 28 15 1,000 4,061E-03 0,02899046 ! inner ear development GO:0048839 79 50 2,000 4,07E-03 0,02897193 ! histone modification GO:0016570 91 50 2,000 4,07E-03 0,02888647 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 2,000 4,304E-03 0,03045883 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 4,304E-03 0,03036951 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! epithelial tube morphogenesis GO:0060562 98 51 2,000 4,304E-03 0,03028071 ! positive regulation of growth GO:0045927 90 52 2,000 4,546E-03 0,0318915 ! covalent chromatin modification GO:0016569 101 52 2,000 4,546E-03 0,03179879 ! synapse organization GO:0050808 85 52 2,000 4,546E-03 0,03170662 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 4,621E-03 0,0321346 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 4,621E-03 0,03204199 ! activation of MAPKK activity GO:0000186 35 16 1,000 4,621E-03 0,03194992 ! glutamate metabolic process GO:0006536 22 16 1,000 4,621E-03 0,03185837 ! negative regulation of tissue remodeling GO:0034104 36 16 1,000 4,621E-03 0,03176734 ! biomineral formation GO:0031214 20 16 1,000 4,621E-03 0,03167684 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 4,621E-03 0,03158685 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 37 16 1,000 4,621E-03 0,03149737 ! metencephalon development GO:0022037 30 17 1,000 5,215E-03 0,03544674 ! negative regulation of cell cycle process GO:0010948 32 17 1,000 5,215E-03 0,03534689 ! signal complex assembly GO:0007172 41 17 1,000 5,215E-03 0,0352476 ! limbic system development GO:0021761 36 17 1,000 5,215E-03 0,03514887 ! regulation of muscle cell differentiation GO:0051147 33 17 1,000 5,215E-03 0,03505069 ! regulation of viral genome replication GO:0045069 28 17 1,000 5,215E-03 0,03495305 ! regulation of survival gene product expression GO:0045884 33 17 1,000 5,215E-03 0,03485596 ! regulation of striated muscle contraction GO:0006942 21 17 1,000 5,215E-03 0,03475941 ! regulation of protein binding GO:0043393 33 17 1,000 5,215E-03 0,03466339 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 1,000 5,215E-03 0,0345679 ! heart morphogenesis GO:0003007 97 55 2,000 5,322E-03 0,03517786 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 5,843E-03 0,03851351 ! patterning of blood vessels GO:0001569 39 18 1,000 5,843E-03 0,03840828 ! epidermis morphogenesis GO:0048730 40 18 1,000 5,843E-03 0,03830363 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 1,000 5,843E-03 0,03819954 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 5,843E-03 0,03809602 ! aromatic compound catabolic process GO:0019439 27 18 1,000 5,843E-03 0,03799306 ! nerve development GO:0021675 28 18 1,000 5,843E-03 0,03789065 ! lipid phosphorylation GO:0046834 35 19 1,000 6,503E-03 0,04205742 ! actin filament bundle formation GO:0051017 42 19 1,000 6,503E-03 0,04194466 ! neuromuscular junction development GO:0007528 34 19 1,000 6,503E-03 0,04183251 ! G1 phase GO:0051318 40 19 1,000 6,503E-03 0,04172096 ! embryonic organ morphogenesis GO:0048562 26 19 1,000 6,503E-03 0,04161 ! camera-type eye development GO:0043010 116 60 2,000 6,782E-03 0,04328088 ! negative regulation of response to stimulus GO:0048585 100 60 2,000 6,782E-03 0,04316638 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 7,195E-03 0,04567511 GO:0010675|regulation of cellular carbohydrate metabolic process, ! camera-type eye morphogenesis GO:0048593 42 20 1,000 7,195E-03 0,04555491 ! negative regulation of T cell activation GO:0050868 40 20 1,000 7,195E-03 0,04543534 ! gonad development GO:0008406 98 62 2,000 7,426E-03 0,04676997 ! regulation of mitosis GO:0007088 105 63 2,000 7,761E-03 0,04875259 GO:0051783|regulation of nuclear division, ! detection of external stimulus GO:0009581 91 63 2,000 7,761E-03 0,04862563 ! cellular amino acid catabolic process GO:0009063 101 63 2,000 7,761E-03 0,04849933 ! ovarian follicle development GO:0001541 35 21 1,000 7,919E-03 0,04935986 ! cell structure disassembly during apoptosis GO:0006921 30 21 1,000 7,919E-03 0,04923232 ! neurotransmitter metabolic process GO:0042133 34 21 1,000 7,919E-03 0,04910543 ! cell aging GO:0007569 44 21 1,000 7,919E-03 0,04897919 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 1,000 7,919E-03 0,04885361 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 1,000 7,919E-03 0,04872866 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 1,000 7,919E-03 0,04860435 ! oogenesis GO:0048477 36 21 1,000 7,919E-03 0,04848068 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 7,919E-03 0,04835763 ! response to cytokine stimulus GO:0034097 63 21 1,000 7,919E-03 0,04823521 ! gut development GO:0048565 39 21 1,000 7,919E-03 0,0481134 ! multicellular organism reproduction GO:0032504 111 64 2,000 8,105E-03 0,04911719 GO:0048609|reproductive process in a multicellular organism, ! germ cell development GO:0007281 118 65 2,000 8,457E-03 0,05112587 ! myeloid cell differentiation GO:0030099 111 65 2,000 8,457E-03 0,05099773 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 8,674E-03 0,0521761 ! regeneration GO:0031099 41 22 1,000 8,674E-03 0,05204599 ! cellular response to reactive oxygen species GO:0034614 31 22 1,000 8,674E-03 0,05191652 ! apoptotic nuclear changes GO:0030262 32 22 1,000 8,674E-03 0,05178769 ! renal system process GO:0003014 41 22 1,000 8,674E-03 0,05165951 ! positive regulation of B cell activation GO:0050871 38 22 1,000 8,674E-03 0,05153195 ! aromatic amino acid family metabolic process GO:0009072 32 22 1,000 8,674E-03 0,05140503 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 1,000 8,674E-03 0,05127872 ! actin filament organization GO:0007015 148 66 2,000 8,819E-03 0,05200507 ! lung development GO:0030324 144 67 2,000 9,189E-03 0,05405759 ! positive regulation of DNA replication GO:0045740 43 23 1,000 9,461E-03 0,05551814 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 9,461E-03 0,05538306 ! myeloid leukocyte differentiation GO:0002573 40 23 1,000 9,461E-03 0,05524864 ! gluconeogenesis GO:0006094 33 23 1,000 9,461E-03 0,05511487 ! regulation of cell-matrix adhesion GO:0001952 78 23 1,000 9,461E-03 0,05498174 GO:0010810|regulation of cell-substrate adhesion, ! response to ethanol GO:0045471 46 23 1,000 9,461E-03 0,05484925 ! regulation of viral reproduction GO:0050792 38 23 1,000 9,461E-03 0,0547174 ! regulation of bone mineralization GO:0030500 49 23 1,000 9,461E-03 0,05458619 ! acetyl-CoA catabolic process GO:0046356 36 23 1,000 9,461E-03 0,0544556 GO:0006099|tricarboxylic acid cycle, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 2,000 9,569E-03 0,05494668 ! cell cycle checkpoint GO:0000075 137 69 2,000 9,957E-03 0,05704164 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 0,01027759 0,05873607 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 0,01027759 0,05859688 ! DNA catabolic process, endonucleolytic GO:0000737 35 24 1,000 0,01027759 0,05845835 ! multicellular organismal response to stress GO:0033555 49 24 1,000 0,01027759 0,05832048 ! regulation of alpha-beta T cell activation GO:0046634 42 24 1,000 0,01027759 0,05818326 ! lymphocyte proliferation GO:0046651 48 24 1,000 0,01027759 0,05804668 ! pallium development GO:0021543 49 24 1,000 0,01027759 0,05791074 ! glutamine family amino acid catabolic process GO:0009065 39 24 1,000 0,01027759 0,05777543 ! protein tetramerization GO:0051262 52 24 1,000 0,01027759 0,05764076 ! respiratory tube development GO:0030323 150 70 2,000 0,010355 0,05793985 ! amine catabolic process GO:0009310 117 71 2,000 0,01076172 0,06007585 ! myelination GO:0042552 45 25 1,000 0,01112459 0,06195779 ! dicarboxylic acid metabolic process GO:0043648 42 25 1,000 0,01112459 0,0618147 ! phototransduction GO:0007602 33 25 1,000 0,01112459 0,06167227 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 1,000 0,01112459 0,0615305 ! osteoblast differentiation GO:0001649 60 25 1,000 0,01112459 0,06138937 ! coenzyme catabolic process GO:0009109 39 25 1,000 0,01112459 0,06124889 ! negative regulation of cell development GO:0010721 73 25 1,000 0,01112459 0,06110905 GO:0050768|negative regulation of neurogenesis, ! interaction with host GO:0051701 62 25 1,000 0,01112459 0,06096985 ! regulation of biomineral formation GO:0070167 51 25 1,000 0,01112459 0,06083129 ! somitogenesis GO:0001756 43 25 1,000 0,01112459 0,06069335 ! cellular response to nutrient levels GO:0031669 41 25 1,000 0,01112459 0,06055603 ! telomere organization GO:0032200 43 25 1,000 0,01112459 0,06041934 GO:0000723|telomere maintenance, ! respiratory system development GO:0060541 153 72 2,000 0,01117757 0,06057037 ! learning or memory GO:0007611 147 73 2,000 0,01160261 0,0627323 ! molting cycle process GO:0022404 50 26 1,000 0,01200128 0,06474235 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! odontogenesis of dentine-containing tooth GO:0042475 48 26 1,000 0,01200128 0,06459751 ! cellular response to oxidative stress GO:0034599 39 26 1,000 0,01200128 0,06445332 ! positive regulation of nuclear division GO:0051785 40 26 1,000 0,01200128 0,06430977 GO:0045840|positive regulation of mitosis, ! blastocyst development GO:0001824 49 26 1,000 0,01200128 0,06416686 ! leukocyte proliferation GO:0070661 52 26 1,000 0,01200128 0,06402458 GO:0032943|mononuclear cell proliferation, ! exocytosis GO:0006887 133 74 2,000 0,01203685 0,06407226 ! eye development GO:0001654 143 74 2,000 0,01203685 0,06393082 ! phosphoinositide-mediated signaling GO:0048015 131 75 2,000 0,01248033 0,06614027 ! lymphocyte differentiation GO:0030098 167 75 2,000 0,01248033 0,0659949 ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 0,01290725 0,06810275 ! mitochondrial membrane organization GO:0007006 57 27 1,000 0,01290725 0,06795373 ! response to toxin GO:0009636 47 27 1,000 0,01290725 0,06780536 ! glutathione metabolic process GO:0006749 39 27 1,000 0,01290725 0,06765763 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 0,01290725 0,06751055 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 0,01290725 0,06736411 ! development of primary sexual characteristics GO:0045137 124 76 2,000 0,01293308 0,06735282 ! regulation of catabolic process GO:0009894 161 76 2,000 0,01293308 0,06720735 ! positive regulation of lymphocyte activation GO:0051251 127 77 2,000 0,01339513 0,06945837 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 1,000 0,0138421 0,0716217 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! positive regulation of T cell differentiation GO:0045582 42 28 1,000 0,0138421 0,07146801 ! synaptogenesis GO:0007416 42 28 1,000 0,0138421 0,07131497 ! regulation of JUN kinase activity GO:0043506 58 28 1,000 0,0138421 0,07116259 ! negative regulation of organelle organization GO:0010639 161 78 2,000 0,0138665 0,07113603 ! response to steroid hormone stimulus GO:0048545 137 78 2,000 0,0138665 0,07098467 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 2,000 0,01434721 0,07328957 ! activation of protein kinase activity GO:0032147 147 79 2,000 0,01434721 0,0731343 ! detection of light stimulus GO:0009583 38 29 1,000 0,01480541 0,07531042 ! negative regulation of neuron apoptosis GO:0043524 56 29 1,000 0,01480541 0,07515153 ! response to metal ion GO:0010038 140 80 2,000 0,01483729 0,07515478 ! T cell activation GO:0042110 168 81 2,000 0,01533675 0,0775215 ! regulation of neuron differentiation GO:0045664 167 81 2,000 0,01533675 0,07735898 ! response to hypoxia GO:0001666 171 81 2,000 0,01533675 0,07719714 ! positive regulation of multicellular organism growth GO:0040018 51 30 1,000 0,0157968 0,07934676 ! ensheathment of neurons GO:0007272 57 30 1,000 0,0157968 0,07918146 GO:0008366|axon ensheathment, ! cofactor catabolic process GO:0051187 51 30 1,000 0,0157968 0,07901684 ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 0,0157968 0,07885291 ! eye morphogenesis GO:0048592 60 30 1,000 0,0157968 0,07868965 ! regulation of B cell activation GO:0050864 50 30 1,000 0,0157968 0,07852707 ! response to oxygen levels GO:0070482 176 83 2,000 0,01636392 0,08117853 ! ovulation cycle process GO:0022602 49 31 1,000 0,01681586 0,08324889 ! triglyceride metabolic process GO:0006641 43 31 1,000 0,01681586 0,08307795 ! erythrocyte differentiation GO:0030218 55 31 1,000 0,01681586 0,0829077 ! myeloid leukocyte activation GO:0002274 49 31 1,000 0,01681586 0,08273816 ! positive regulation of cell activation GO:0050867 145 85 2,000 0,01742883 0,08557911 GO:0002696|positive regulation of leukocyte activation, ! response to hydrogen peroxide GO:0042542 50 32 1,000 0,0178622 0,08752844 ! response to ionizing radiation GO:0010212 65 32 1,000 0,0178622 0,08735054 ! response to mechanical stimulus GO:0009612 57 32 1,000 0,0178622 0,08717335 ! hexose biosynthetic process GO:0019319 48 32 1,000 0,0178622 0,08699689 ! ovulation cycle GO:0042698 51 32 1,000 0,0178622 0,08682114 ! peripheral nervous system development GO:0007422 64 32 1,000 0,0178622 0,0866461 ! BMP signaling pathway GO:0030509 64 32 1,000 0,0178622 0,08647176 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 1,000 0,0178622 0,08629812 ! response to inorganic substance GO:0010035 153 86 2,000 0,01797548 0,08667133 ! mitochondrion organization GO:0007005 148 86 2,000 0,01797548 0,08649799 ! nitrogen compound catabolic process GO:0044270 143 87 2,000 0,0185316 0,08899604 ! post-embryonic development GO:0009791 69 33 1,000 0,01893544 0,09075434 ! positive regulation of neurogenesis GO:0050769 67 33 1,000 0,01893544 0,09057391 ! cell fate specification GO:0001708 52 33 1,000 0,01893544 0,0903942 ! negative regulation of protein transport GO:0051224 69 33 1,000 0,01893544 0,09021521 ! regulation of striated muscle tissue development GO:0016202 69 34 1,000 0,0200352 0,09526617 ! mismatch repair GO:0006298 46 34 1,000 0,0200352 0,09507827 ! placenta development GO:0001890 53 34 1,000 0,0200352 0,09489111 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 1,000 0,0200352 0,09470468 ! regulation of cell cycle process GO:0010564 149 90 2,000 0,02025689 0,09556485 ! response to protein stimulus GO:0051789 149 91 2,000 0,02085098 0,09817508 ! regulation of muscle development GO:0048634 70 35 1,000 0,02116108 0,09944054 ! negative regulation of DNA metabolic process GO:0051053 61 35 1,000 0,02116108 0,0992467 ! odontogenesis GO:0042476 66 35 1,000 0,02116108 0,09905361 ! female gonad development GO:0008585 58 35 1,000 0,02116108 0,09886128 ! neutral lipid metabolic process GO:0006638 50 35 1,000 0,02116108 0,09866969 GO:0006639|acylglycerol metabolic process, ! telencephalon development GO:0021537 68 35 1,000 0,02116108 0,09847884 ! calcium-mediated signaling GO:0019722 62 35 1,000 0,02116108 0,09828872 ! regulation of defense response GO:0031347 149 92 2,000 0,02145459 0,09945999 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 2,000 0,0220677 0,10210555 GO:0010498|proteasomal protein catabolic process, ! mitotic sister chromatid segregation GO:0000070 57 36 1,000 0,02231272 0,10304108 ! aerobic respiration GO:0009060 55 36 1,000 0,02231272 0,10284368 ! androgen receptor signaling pathway GO:0030521 74 36 1,000 0,02231272 0,10264704 ! monosaccharide biosynthetic process GO:0046364 52 36 1,000 0,02231272 0,10245115 ! negative regulation of cell activation GO:0050866 65 36 1,000 0,02231272 0,102256 ! female pregnancy GO:0007565 164 94 2,000 0,02269032 0,10378881 ! sister chromatid segregation GO:0000819 58 37 1,000 0,02348974 0,10724159 ! glycerol ether metabolic process GO:0006662 53 37 1,000 0,02348974 0,10703848 ! regulation of protein stability GO:0031647 73 37 1,000 0,02348974 0,10683614 ! pigment metabolic process GO:0042440 80 37 1,000 0,02348974 0,10663456 ! detection of stimulus GO:0051606 151 96 2,000 0,02396409 0,10858305 ! regulation of protein localization GO:0032880 176 97 2,000 0,02461523 0,11132378 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 0,02469178 0,11146044 ! mitotic cell cycle checkpoint GO:0007093 76 38 1,000 0,02469178 0,11125171 ! carbohydrate homeostasis GO:0033500 53 38 1,000 0,02469178 0,11104376 GO:0042593|glucose homeostasis, ! development of primary female sexual characteristics GO:0046545 67 38 1,000 0,02469178 0,11083659 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 1,000 0,02469178 0,11063019 ! erythrocyte homeostasis GO:0034101 64 38 1,000 0,02469178 0,11042456 ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 0,02469178 0,11021969 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! carboxylic acid catabolic process GO:0046395 156 98 2,000 0,02527588 0,11261808 GO:0016054|organic acid catabolic process, ! mammary gland development GO:0030879 86 39 1,000 0,02591846 0,11526768 ! learning GO:0007612 77 39 1,000 0,02591846 0,11505501 ! ear morphogenesis GO:0042471 60 39 1,000 0,02591846 0,11484312 ! organic ether metabolic process GO:0018904 55 39 1,000 0,02591846 0,11463201 ! segmentation GO:0035282 67 39 1,000 0,02591846 0,11442168 ! regulation of action potential in neuron GO:0019228 73 39 1,000 0,02591846 0,11421211 ! skeletal muscle tissue development GO:0007519 186 99 2,000 0,02594602 0,11412452 GO:0060538|skeletal muscle organ development, ! cytokinesis GO:0000910 72 40 1,000 0,02716943 0,11928768 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 1,000 0,02844433 0,12465766 ! regulation of T cell proliferation GO:0042129 71 41 1,000 0,02844433 0,12443101 ! female gamete generation GO:0007292 61 41 1,000 0,02844433 0,12420518 ! dorsal/ventral pattern formation GO:0009953 68 41 1,000 0,02844433 0,12398017 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 0,0297428 0,12940539 GO:0090047|positive regulation of transcription regulator activity, ! alcohol biosynthetic process GO:0046165 59 42 1,000 0,0297428 0,1291718 ! regulation of intracellular protein transport GO:0033157 80 42 1,000 0,0297428 0,12893906 ! epithelial cell differentiation GO:0030855 79 43 1,000 0,0310645 0,13442658 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 1,000 0,0310645 0,13418524 ! glucose transport GO:0015758 65 43 1,000 0,0310645 0,13394476 ! striated muscle cell differentiation GO:0051146 82 43 1,000 0,0310645 0,13370515 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,03163573 0,13592067 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,03163573 0,13567838 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,03163573 0,13543696 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,03163573 0,1351964 ! neuron fate determination GO:0048664 7 5 0,000 0,03163573 0,13495669 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03163573 0,13471783 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,03163573 0,13447981 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,03163573 0,13424263 ! polyol transport GO:0015791 12 5 0,000 0,03163573 0,13400629 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,03163573 0,13377078 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,03163573 0,13353609 ! response to superoxide GO:0000303 10 5 0,000 0,03163573 0,13330223 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,03163573 0,13306918 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,03163573 0,13283695 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,03163573 0,13260553 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,03163573 0,13237491 ! female meiosis GO:0007143 7 5 0,000 0,03163573 0,13214509 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,03163573 0,13191607 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,03163573 0,13168784 ! cobalt ion transport GO:0006824 11 5 0,000 0,03163573 0,1314604 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,03163573 0,13123375 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,03163573 0,13100787 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,03163573 0,13078277 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,03163573 0,13055845 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,03163573 0,13033489 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,03163573 0,13011209 ! selenocysteine incorporation GO:0001514 12 5 0,000 0,03163573 0,12989006 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,03163573 0,12966878 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,03163573 0,12944825 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03163573 0,12922848 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03163573 0,12900945 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,03163573 0,12879116 ! negative chemotaxis GO:0050919 14 5 0,000 0,03163573 0,1285736 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03163573 0,12835679 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,03163573 0,1281407 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,03163573 0,12792533 ! behavioral response to pain GO:0048266 9 5 0,000 0,03163573 0,12771069 ! clathrin coat assembly GO:0048268 14 5 0,000 0,03163573 0,12749677 ! Notch receptor processing GO:0007220 8 5 0,000 0,03163573 0,12728357 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03163573 0,12707107 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,03163573 0,12685929 ! micturition GO:0060073 9 5 0,000 0,03163573 0,12664821 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,03163573 0,12643783 ! copulation GO:0007620 9 5 0,000 0,03163573 0,12622815 ! glial cell fate commitment GO:0021781 13 5 0,000 0,03163573 0,12601916 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,03163573 0,12581087 ! spermidine metabolic process GO:0008216 7 5 0,000 0,03163573 0,12560326 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,03163573 0,12539633 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,03163573 0,12519009 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,03163573 0,12498452 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,03163573 0,12477963 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,03163573 0,12457541 ! grooming behavior GO:0007625 6 5 0,000 0,03163573 0,12437185 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,03163573 0,12416896 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03163573 0,12396673 ! response to protozoan GO:0001562 10 5 0,000 0,03163573 0,12376516 ! lymph vessel development GO:0001945 10 5 0,000 0,03163573 0,12356424 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,03163573 0,12336398 ! endochondral ossification GO:0001958 16 5 0,000 0,03163573 0,12316436 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,03163573 0,12296539 ! anagen GO:0042640 6 5 0,000 0,03163573 0,12276705 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,03163573 0,12256936 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,03163573 0,1223723 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,03163573 0,12217588 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,03163573 0,12198009 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,03163573 0,12178492 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,03163573 0,12159037 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,03163573 0,12139645 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,03163573 0,12120314 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,03163573 0,12101045 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,03163573 0,12081837 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,03163573 0,1206269 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,03163573 0,12043603 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,03163573 0,12024577 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,03163573 0,12005611 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,03163573 0,11986704 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,03163573 0,11967857 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,03163573 0,1194907 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,03163573 0,11930341 ! histidine catabolic process GO:0006548 6 5 0,000 0,03163573 0,1191167 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,03163573 0,11893058 ! microvillus organization GO:0032528 7 5 0,000 0,03163573 0,11874504 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,03163573 0,11856008 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,03163573 0,1183757 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03163573 0,11819188 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,03163573 0,11800864 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,03163573 0,11782597 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03163573 0,11764385 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,03163573 0,1174623 ! polyol catabolic process GO:0046174 7 5 0,000 0,03163573 0,11728132 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03163573 0,11710088 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03163573 0,116921 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03163573 0,11674168 ! muscle cell migration GO:0014812 8 5 0,000 0,03163573 0,1165629 ! mitochondrial fission GO:0000266 8 5 0,000 0,03163573 0,11638467 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,03163573 0,11620698 ! mRNA transcription GO:0009299 9 5 0,000 0,03163573 0,11602984 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,03163573 0,11585323 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,03163573 0,11567716 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,03163573 0,11550163 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03163573 0,11532663 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,03163573 0,11515215 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,03163573 0,11497821 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,03163573 0,11480479 ! response to food GO:0032094 6 5 0,000 0,03163573 0,11463189 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,03163573 0,11445951 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,03163573 0,11428765 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03163573 0,1141163 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,03163573 0,11394547 ! forebrain neuron development GO:0021884 13 5 0,000 0,03163573 0,11377515 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,03163573 0,11360533 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,03163573 0,11343603 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,03163573 0,11326722 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03163573 0,11309892 GO:0009251|glucan catabolic process, ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,03163573 0,11293112 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03163573 0,11276381 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,03163573 0,112597 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,03163573 0,11243068 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03163573 0,11226486 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,03163573 0,11209952 ! basic amino acid transport GO:0015802 11 5 0,000 0,03163573 0,11193467 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03163573 0,1117703 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,03163573 0,11160641 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03163573 0,11144301 ! depyrimidination GO:0045008 10 5 0,000 0,03163573 0,11128008 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,03163573 0,11111763 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03163573 0,11095565 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,03163573 0,11079414 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,03163573 0,1106331 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03163573 0,11047253 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,03163573 0,11031243 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,03163573 0,11015278 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,03163573 0,1099936 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,03163573 0,10983488 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,03163573 0,10967662 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03163573 0,10951881 ! response to arsenic GO:0046685 10 5 0,000 0,03163573 0,10936146 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,03163573 0,10920455 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,03163573 0,1090481 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,03163573 0,10889209 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,03163573 0,10873653 ! response to cadmium ion GO:0046686 7 5 0,000 0,03163573 0,10858142 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,03163573 0,10842674 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,03163573 0,10827251 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,03163573 0,10811871 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,03163573 0,10796535 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,03163573 0,10781243 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03163573 0,10765993 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03163573 0,10750787 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,03163573 0,10735624 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03163573 0,10720503 ! neural tube patterning GO:0021532 7 5 0,000 0,03163573 0,10705425 ! embryonic cleavage GO:0040016 6 5 0,000 0,03163573 0,1069039 ! peroxisome fission GO:0016559 5 5 0,000 0,03163573 0,10675396 ! histone demethylation GO:0016577 10 5 0,000 0,03163573 0,10660444 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,03163573 0,10645535 ! mitotic recombination GO:0006312 9 5 0,000 0,03163573 0,10630667 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,03163573 0,1061584 ! metaphase plate congression GO:0051310 7 5 0,000 0,03163573 0,10601055 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03163573 0,10586311 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,03163573 0,10571607 ! enteric nervous system development GO:0048484 8 5 0,000 0,03163573 0,10556945 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,03163573 0,10542323 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,03163573 0,10527742 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,03163573 0,10513201 ! muscle cell proliferation GO:0033002 11 5 0,000 0,03163573 0,104987 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,03163573 0,10484239 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,03163573 0,10469818 ! plasminogen activation GO:0031639 5 5 0,000 0,03163573 0,10455436 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,03163573 0,10441094 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,03163573 0,10426791 ! metaphase GO:0051323 8 5 0,000 0,03163573 0,10412527 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,03163573 0,10398302 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,03163573 0,10384116 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03163573 0,10369969 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03163573 0,1035586 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,03163573 0,1034179 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,03163573 0,10327758 ! response to redox state GO:0051775 5 5 0,000 0,03163573 0,10313763 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,03163573 0,10299807 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,03163573 0,10285888 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,03163573 0,10272007 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,03163573 0,10258164 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03163573 0,10244357 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,03163573 0,10230588 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03163573 0,10216856 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,03163573 0,1020316 ! striatum development GO:0021756 9 5 0,000 0,03163573 0,10189501 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,03163573 0,10175879 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,03163573 0,10162293 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,03163573 0,10148743 ! glial cell migration GO:0008347 11 5 0,000 0,03163573 0,1013523 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,03163573 0,10121752 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03163573 0,1010831 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,03163573 0,10094904 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,03163573 0,10081533 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,03163573 0,10068198 ! neuroprotection GO:0043526 6 5 0,000 0,03163573 0,10054897 ! neural plate development GO:0001840 8 5 0,000 0,03163573 0,10041632 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,03163573 0,10028402 ! regulation of sensory perception GO:0051931 7 5 0,000 0,03163573 0,10015207 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,03163573 0,10002046 GO:0046831|regulation of RNA export from nucleus, ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,03163573 0,0998892 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,03163573 0,09975829 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,03163573 0,09962771 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,03163573 0,09949748 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03163573 0,09936759 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,03163573 0,09923804 ! spindle assembly GO:0051225 6 5 0,000 0,03163573 0,09910882 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,03163573 0,09897994 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,03163573 0,09885139 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,03163573 0,09872318 ! drug metabolic process GO:0017144 6 5 0,000 0,03163573 0,0985953 ! stem cell division GO:0017145 11 5 0,000 0,03163573 0,09846775 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,03163573 0,09834053 ! organ regeneration GO:0031100 7 5 0,000 0,03163573 0,09821364 ! carnitine metabolic process GO:0009437 7 5 0,000 0,03163573 0,09808708 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,03163573 0,09796084 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,03163573 0,09783493 ! hexose transport GO:0008645 67 44 1,000 0,03240907 0,10009783 GO:0015749|monosaccharide transport, ! B cell differentiation GO:0030183 107 44 1,000 0,03240907 0,0999695 ! developmental growth GO:0048589 82 44 1,000 0,03240907 0,0998415 ! maintenance of location in cell GO:0051651 97 44 1,000 0,03240907 0,09971383 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 1,000 0,03516546 0,10805631 ! negative regulation of cell migration GO:0030336 115 46 1,000 0,03516546 0,10791848 ! positive regulation of DNA binding GO:0043388 73 47 1,000 0,0365766 0,11210612 ! regulation of JNK cascade GO:0046328 94 47 1,000 0,0365766 0,11196349 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,03784237 0,11569091 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,03784237 0,11554409 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,03784237 0,11539765 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03784237 0,11525158 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,03784237 0,11510587 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,03784237 0,11496054 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,03784237 0,11481557 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,03784237 0,11467096 ! sleep GO:0030431 13 6 0,000 0,03784237 0,11452672 ! response to oxygen radical GO:0000305 11 6 0,000 0,03784237 0,11438285 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,03784237 0,11423933 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,03784237 0,11409617 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,03784237 0,11395337 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,03784237 0,11381093 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,03784237 0,11366885 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,03784237 0,11352711 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,03784237 0,11338574 ! forebrain regionalization GO:0021871 8 6 0,000 0,03784237 0,11324471 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,03784237 0,11310403 ! male meiosis GO:0007140 7 6 0,000 0,03784237 0,1129637 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,03784237 0,11282373 ! response to zinc ion GO:0010043 9 6 0,000 0,03784237 0,11268409 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,03784237 0,1125448 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,03784237 0,11240586 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,03784237 0,11226726 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,03784237 0,112129 ! malate metabolic process GO:0006108 11 6 0,000 0,03784237 0,11199108 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,03784237 0,1118535 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,03784237 0,11171625 ! protein refolding GO:0042026 15 6 0,000 0,03784237 0,11157935 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,03784237 0,11144277 ! opsonization GO:0008228 8 6 0,000 0,03784237 0,11130654 ! mating behavior GO:0007617 7 6 0,000 0,03784237 0,11117063 ! neuron remodeling GO:0016322 15 6 0,000 0,03784237 0,11103506 ! erythrocyte maturation GO:0043249 7 6 0,000 0,03784237 0,11089981 ! equilibrioception GO:0050957 14 6 0,000 0,03784237 0,1107649 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,03784237 0,11063031 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,03784237 0,11049605 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03784237 0,11036212 GO:0046530|photoreceptor cell differentiation, ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,03784237 0,11022851 ! response to interferon-gamma GO:0034341 15 6 0,000 0,03784237 0,11009522 ! toxin metabolic process GO:0009404 11 6 0,000 0,03784237 0,10996225 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,03784237 0,10982961 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03784237 0,10969728 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,03784237 0,10956528 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,03784237 0,10943359 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 12 6 0,000 0,03784237 0,10930222 ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,03784237 0,10917116 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,03784237 0,10904041 ! thymic T cell selection GO:0045061 12 6 0,000 0,03784237 0,10890998 ! protein lipoylation GO:0009249 10 6 0,000 0,03784237 0,10877986 ! cysteine metabolic process GO:0006534 10 6 0,000 0,03784237 0,10865006 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,03784237 0,10852056 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03784237 0,10839136 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,03784237 0,10826248 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,03784237 0,1081339 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,03784237 0,10800563 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,03784237 0,10787766 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,03784237 0,10775 ! hyperosmotic response GO:0006972 9 6 0,000 0,03784237 0,10762263 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,03784237 0,10749557 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,03784237 0,1073688 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,03784237 0,10724234 ! urea metabolic process GO:0019627 7 6 0,000 0,03784237 0,10711617 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,03784237 0,1069903 ! neutrophil activation GO:0042119 8 6 0,000 0,03784237 0,10686473 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,03784237 0,10673944 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,03784237 0,10661446 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,03784237 0,10648976 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03784237 0,10636536 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,03784237 0,10624124 ! neuron apoptosis GO:0051402 9 6 0,000 0,03784237 0,10611742 ! nucleoside salvage GO:0043174 9 6 0,000 0,03784237 0,10599388 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,03784237 0,10587064 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,03784237 0,10574767 ! T cell mediated immunity GO:0002456 16 6 0,000 0,03784237 0,105625 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,03784237 0,1055026 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,03784237 0,10538049 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,03784237 0,10525867 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03784237 0,10513712 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,03784237 0,10501585 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,03784237 0,10489487 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,03784237 0,10477416 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,03784237 0,10465373 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,03784237 0,10453358 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,03784237 0,1044137 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,03784237 0,1042941 ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,03784237 0,10417477 ! monocyte differentiation GO:0030224 12 6 0,000 0,03784237 0,10405571 ! response to UV-C GO:0010225 11 6 0,000 0,03784237 0,10393692 ! astrocyte development GO:0014002 15 6 0,000 0,03784237 0,10381841 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,03784237 0,10370017 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,03784237 0,10358219 ! interaction with symbiont GO:0051702 13 6 0,000 0,03784237 0,10346448 ! regulation of dendrite development GO:0050773 16 6 0,000 0,03784237 0,10334704 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03784237 0,10322987 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,03784237 0,10311296 ! response to copper ion GO:0046688 10 6 0,000 0,03784237 0,10299632 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,03784237 0,10287994 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03784237 0,10276382 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03784237 0,10264797 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,03784237 0,10253237 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,03784237 0,10241704 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,03784237 0,10230196 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,03784237 0,10218714 ! hair follicle maturation GO:0048820 7 6 0,000 0,03784237 0,10207259 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,03784237 0,10195828 ! Schwann cell development GO:0014044 15 6 0,000 0,03784237 0,10184424 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,03784237 0,10173044 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03784237 0,1016169 ! subpallium development GO:0021544 10 6 0,000 0,03784237 0,10150362 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,03784237 0,10139059 ! histone ubiquitination GO:0016574 8 6 0,000 0,03784237 0,1012778 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,03784237 0,10116527 ! maintenance of organ identity GO:0048496 9 6 0,000 0,03784237 0,10105299 ! G2 phase GO:0051319 16 6 0,000 0,03784237 0,10094096 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,03784237 0,10082918 ! establishment of planar polarity GO:0001736 7 6 0,000 0,03784237 0,10071764 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,03784237 0,10060635 ! membrane to membrane docking GO:0022614 14 6 0,000 0,03784237 0,1004953 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,03784237 0,10038451 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,03784237 0,10027395 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,03784237 0,10016364 ! receptor internalization GO:0031623 10 6 0,000 0,03784237 0,10005357 ! positive regulation of pseudopodium assembly GO:0031274 14 6 0,000 0,03784237 0,09994374 GO:0031272|regulation of pseudopodium assembly, ! neutrophil homeostasis GO:0001780 10 6 0,000 0,03784237 0,09983415 ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,03784237 0,0997248 ! protein deubiquitination GO:0016579 14 6 0,000 0,03784237 0,0996157 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,03784237 0,09950683 ! protein destabilization GO:0031648 9 6 0,000 0,03784237 0,09939819 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,03784237 0,0992898 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,03784237 0,09918164 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,03784237 0,09907372 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,03784237 0,09896603 ! progesterone metabolic process GO:0042448 10 6 0,000 0,03784237 0,09885857 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,03784237 0,09875135 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,03784237 0,09864436 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,03784237 0,0985376 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,03784237 0,09843108 ! determination of adult lifespan GO:0008340 15 6 0,000 0,03784237 0,09832478 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,03784237 0,09821871 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,03784237 0,09811287 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,03784237 0,09800726 ! catecholamine transport GO:0051937 9 6 0,000 0,03784237 0,09790188 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,03784237 0,09779672 ! sensory cilium assembly GO:0035058 10 6 0,000 0,03784237 0,09769179 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03784237 0,09758708 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,03784237 0,0974826 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,03784237 0,09737834 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,03784237 0,0972743 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,03784237 0,09717049 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,03784237 0,09706689 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03784237 0,09696352 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,03784237 0,09686037 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,03784237 0,09675743 ! mitochondrial transport GO:0006839 82 48 1,000 0,03800926 0,09708098 ! cellular component disassembly GO:0022411 86 48 1,000 0,03800926 0,09697803 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 1,000 0,03800926 0,0968753 ! activation of caspase activity GO:0006919 84 48 1,000 0,03800926 0,09677279 ! peptide metabolic process GO:0006518 76 49 1,000 0,03946311 0,10036813 ! endocrine system development GO:0035270 104 49 1,000 0,03946311 0,10026214 ! negative regulation of immune system process GO:0002683 95 50 1,000 0,04093782 0,10389916 ! positive regulation of binding GO:0051099 78 51 1,000 0,04243307 0,10758058 ! response to estrogen stimulus GO:0043627 93 51 1,000 0,04243307 0,10746734 ! chromatin remodeling GO:0006338 109 51 1,000 0,04243307 0,10735434 ! vesicle organization GO:0016050 107 51 1,000 0,04243307 0,10724157 ! regulation of cell shape GO:0008360 125 51 1,000 0,04243307 0,10712904 ! regulation of angiogenesis GO:0045765 114 52 1,000 0,04394854 0,11083876 ! tRNA transcription GO:0009304 14 7 0,000 0,04400943 0,11087612 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,04400943 0,11076015 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 0,04400943 0,11064441 ! regulation of helicase activity GO:0051095 15 7 0,000 0,04400943 0,11052891 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,04400943 0,11041366 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,04400943 0,11029864 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,04400943 0,11018387 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,04400943 0,11006933 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,04400943 0,10995504 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,04400943 0,10984097 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04400943 0,10972715 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,04400943 0,10961356 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,04400943 0,10950021 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04400943 0,10938709 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,04400943 0,1092742 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,04400943 0,10916155 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,04400943 0,10904912 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,04400943 0,10893693 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,04400943 0,10882497 ! glycolipid transport GO:0046836 10 7 0,000 0,04400943 0,10871324 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,04400943 0,10860174 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,04400943 0,10849047 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,04400943 0,10837943 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,04400943 0,10826861 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,04400943 0,10815802 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,04400943 0,10804765 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,04400943 0,10793751 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,04400943 0,1078276 ! mRNA stabilization GO:0048255 18 7 0,000 0,04400943 0,1077179 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,04400943 0,10760843 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,04400943 0,10749919 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,04400943 0,10739016 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,04400943 0,10728136 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04400943 0,10717277 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,04400943 0,10706441 ! lipoprotein transport GO:0042953 14 7 0,000 0,04400943 0,10695626 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04400943 0,10684833 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04400943 0,10674062 ! rhythmic behavior GO:0007622 15 7 0,000 0,04400943 0,10663313 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,04400943 0,10652585 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,04400943 0,10641879 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,04400943 0,10631195 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,04400943 0,10620531 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,04400943 0,1060989 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,04400943 0,10599269 ! mechanosensory behavior GO:0007638 14 7 0,000 0,04400943 0,1058867 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,04400943 0,10578092 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04400943 0,10567535 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,04400943 0,10556999 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04400943 0,10546484 ! spinal cord patterning GO:0021511 13 7 0,000 0,04400943 0,1053599 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,04400943 0,10525517 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,04400943 0,10515064 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,04400943 0,10504633 ! adrenal gland development GO:0030325 17 7 0,000 0,04400943 0,10494222 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,04400943 0,10483832 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,04400943 0,10473462 ! ovulation GO:0030728 9 7 0,000 0,04400943 0,10463113 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,04400943 0,10452784 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,04400943 0,10442475 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! microtubule nucleation GO:0007020 20 7 0,000 0,04400943 0,10432187 ! proline biosynthetic process GO:0006561 10 7 0,000 0,04400943 0,10421919 ! thyroid hormone generation GO:0006590 13 7 0,000 0,04400943 0,10411671 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,04400943 0,10401444 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,04400943 0,10391236 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,04400943 0,10381049 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04400943 0,10370881 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04400943 0,10360734 ! galactose metabolic process GO:0006012 13 7 0,000 0,04400943 0,10350606 ! vesicle fusion GO:0006906 17 7 0,000 0,04400943 0,10340498 ! response to dietary excess GO:0002021 8 7 0,000 0,04400943 0,1033041 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,04400943 0,10320341 ! intracellular pH reduction GO:0051452 11 7 0,000 0,04400943 0,10310292 GO:0045851|pH reduction, ! melanosome organization GO:0032438 9 7 0,000 0,04400943 0,10300263 ! purine salvage GO:0043101 10 7 0,000 0,04400943 0,10290253 ! nucleoside transport GO:0015858 8 7 0,000 0,04400943 0,10280262 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,04400943 0,10270291 ! parturition GO:0007567 14 7 0,000 0,04400943 0,10260339 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,04400943 0,10250406 ! rRNA modification GO:0000154 14 7 0,000 0,04400943 0,10240493 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,04400943 0,10230599 ! spindle checkpoint GO:0031577 15 7 0,000 0,04400943 0,10220724 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,04400943 0,10210868 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,04400943 0,10201031 ! macrophage differentiation GO:0030225 11 7 0,000 0,04400943 0,10191213 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04400943 0,10181413 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,04400943 0,10171633 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,04400943 0,10161871 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,04400943 0,10152128 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,04400943 0,10142404 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,04400943 0,10132698 ! fibrinolysis GO:0042730 10 7 0,000 0,04400943 0,10123011 ! eating behavior GO:0042755 7 7 0,000 0,04400943 0,10113343 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,04400943 0,10103693 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,04400943 0,10094061 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,04400943 0,10084448 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,04400943 0,10074852 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,04400943 0,10065276 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,04400943 0,10055717 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,04400943 0,10046176 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,04400943 0,10036654 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,04400943 0,1002715 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,04400943 0,10017663 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,04400943 0,10008195 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,04400943 0,09998744 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,04400943 0,09989311 ! regulation of meiosis GO:0040020 12 7 0,000 0,04400943 0,09979896 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,04400943 0,09970499 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,04400943 0,09961119 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,04400943 0,09951757 ! oxygen homeostasis GO:0032364 12 7 0,000 0,04400943 0,09942413 ! transcription termination GO:0006353 13 7 0,000 0,04400943 0,09933086 ! response to tumor cell GO:0002347 13 7 0,000 0,04400943 0,09923777 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,04400943 0,09914485 ! anaphase GO:0051322 17 7 0,000 0,04400943 0,0990521 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,04400943 0,09895953 ! axonal fasciculation GO:0007413 18 7 0,000 0,04400943 0,09886713 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,04400943 0,09877491 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,04400943 0,09868285 ! diuresis GO:0030146 12 7 0,000 0,04400943 0,09859097 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,04400943 0,09849925 ! thiamin metabolic process GO:0006772 7 7 0,000 0,04400943 0,09840771 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04400943 0,09831634 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,04400943 0,09822514 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,04400943 0,0981341 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,04400943 0,09804324 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04400943 0,09795254 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04400943 0,09786201 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04400943 0,09777165 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,04400943 0,09768146 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,04400943 0,09759143 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,04400943 0,09750156 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 10 7 0,000 0,04400943 0,09741187 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,04400943 0,09732233 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04400943 0,09723296 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,04400943 0,09714376 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,04400943 0,09705472 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,04400943 0,09696584 ! adult feeding behavior GO:0008343 9 7 0,000 0,04400943 0,09687713 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,04400943 0,09678857 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,04400943 0,09670018 ! muscle adaptation GO:0043500 14 7 0,000 0,04400943 0,09661195 ! embryonic heart tube development GO:0035050 10 7 0,000 0,04400943 0,09652388 ! retina homeostasis GO:0001895 12 7 0,000 0,04400943 0,09643597 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,04400943 0,09634822 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,04400943 0,09626064 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,04400943 0,09617321 ! protein prenylation GO:0018342 18 7 0,000 0,04400943 0,09608593 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,04400943 0,09599882 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,04400943 0,09591186 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04400943 0,09582507 ! regulation of translational initiation GO:0006446 82 53 1,000 0,0454839 0,09894599 ! cell maturation GO:0048469 100 53 1,000 0,0454839 0,09885661 ! regulation of neuron apoptosis GO:0043523 100 53 1,000 0,0454839 0,09876739 ! activation of phospholipase C activity GO:0007202 103 54 1,000 0,04703885 0,10205182 GO:0010863|positive regulation of phospholipase C activity, ! glutamine family amino acid metabolic process GO:0009064 78 54 1,000 0,04703885 0,10195988 ! positive regulation of caspase activity GO:0043280 95 55 1,000 0,04861307 0,10527727 GO:0010952|positive regulation of peptidase activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 0,04861307 0,10518259 ! regulation of protein catabolic process GO:0042176 116 55 1,000 0,04861307 0,10508809 ! aging GO:0007568 103 55 1,000 0,04861307 0,10499375 ! regulation of multicellular organism growth GO:0040014 85 55 1,000 0,04861307 0,10489959 ! negative regulation of cell motion GO:0051271 134 55 1,000 0,04861307 0,10480559 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,05013717 0,10799466 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,05013717 0,10789806 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,05013717 0,10780164 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,05013717 0,10770539 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,05013717 0,10760931 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,05013717 0,1075134 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,05013717 0,10741766 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,05013717 0,1073221 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,05013717 0,1072267 ! meiotic prophase I GO:0007128 13 8 0,000 0,05013717 0,10713147 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,05013717 0,10703641 ! oligopeptide transport GO:0006857 15 8 0,000 0,05013717 0,10694152 ! UTP metabolic process GO:0046051 8 8 0,000 0,05013717 0,1068468 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,05013717 0,10675224 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,05013717 0,10665786 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,05013717 0,10656364 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,05013717 0,10646958 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,05013717 0,10637569 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,05013717 0,10628197 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,05013717 0,10618841 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,05013717 0,10609502 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,05013717 0,10600179 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05013717 0,10590872 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,05013717 0,10581582 ! reflex GO:0060004 16 8 0,000 0,05013717 0,10572308 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,05013717 0,1056305 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,05013717 0,10553809 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,05013717 0,10544584 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,05013717 0,10535374 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,05013717 0,10526181 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,05013717 0,10517004 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,05013717 0,10507843 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,05013717 0,10498698 ! astrocyte differentiation GO:0048708 18 8 0,000 0,05013717 0,10489568 ! histidine metabolic process GO:0006547 16 8 0,000 0,05013717 0,10480455 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,05013717 0,10471357 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,05013717 0,10462275 ! glycine catabolic process GO:0006546 13 8 0,000 0,05013717 0,10453209 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,05013717 0,10444159 ! ER overload response GO:0006983 12 8 0,000 0,05013717 0,10435124 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,05013717 0,10426105 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,05013717 0,10417102 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,05013717 0,10408114 ! macrophage activation GO:0042116 12 8 0,000 0,05013717 0,10399141 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,05013717 0,10390184 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,05013717 0,10381242 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,05013717 0,10372316 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,05013717 0,10363405 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,05013717 0,10354509 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,05013717 0,10345629 ! osteoblast development GO:0002076 16 8 0,000 0,05013717 0,10336764 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,05013717 0,10327914 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,05013717 0,10319079 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,05013717 0,10310259 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,05013717 0,10301455 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,05013717 0,10292665 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,05013717 0,1028389 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,05013717 0,10275131 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,05013717 0,10266386 ! intermediate filament organization GO:0045109 12 8 0,000 0,05013717 0,10257656 ! cardiac muscle cell differentiation GO:0055007 27 8 0,000 0,05013717 0,10248941 ! cellular extravasation GO:0045123 12 8 0,000 0,05013717 0,10240241 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,05013717 0,10231555 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,05013717 0,10222884 ! response to antibiotic GO:0046677 11 8 0,000 0,05013717 0,10214228 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,05013717 0,10205587 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,05013717 0,1019696 ! DNA topological change GO:0006265 12 8 0,000 0,05013717 0,10188348 ! response to tropane GO:0014073 15 8 0,000 0,05013717 0,1017975 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,05013717 0,10171167 ! melanosome transport GO:0032402 13 8 0,000 0,05013717 0,10162598 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,05013717 0,10154043 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,05013717 0,10145503 ! mast cell activation GO:0045576 14 8 0,000 0,05013717 0,10136978 ! multicellular organismal aging GO:0010259 18 8 0,000 0,05013717 0,10128466 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,05013717 0,10119969 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,05013717 0,10111487 ! nucleosome disassembly GO:0006337 14 8 0,000 0,05013717 0,10103018 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,05013717 0,10094564 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 16 8 0,000 0,05013717 0,10086123 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,05013717 0,10077697 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,05013717 0,10069285 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,05013717 0,10060887 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,05013717 0,10052503 ! intracellular lipid transport GO:0032365 13 8 0,000 0,05013717 0,10044133 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,05013717 0,10035777 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,05013717 0,10027434 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,05013717 0,10019106 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,05013717 0,10010791 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,05013717 0,10002491 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,05013717 0,09994203 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,05013717 0,0998593 ! hormone catabolic process GO:0042447 17 8 0,000 0,05013717 0,0997767 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,05013717 0,09969424 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,05013717 0,09961192 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,05013717 0,09952973 ! ATP catabolic process GO:0006200 11 8 0,000 0,05013717 0,09944768 ! blastocyst growth GO:0001832 19 8 0,000 0,05013717 0,09936576 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,05013717 0,09928398 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,05013717 0,09920233 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,05013717 0,09912082 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,05013717 0,09903944 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,05013717 0,09895819 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,05013717 0,09887708 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,05013717 0,0987961 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,05013717 0,09871525 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,05013717 0,09863453 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,05013717 0,09855395 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,05013717 0,0984735 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,05013717 0,09839318 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,05013717 0,09831299 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,05013717 0,09823293 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,05013717 0,098153 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,05013717 0,0980732 ! skeletal muscle fiber development GO:0048741 111 56 1,000 0,05020625 0,09812855 ! regulation of DNA replication GO:0006275 101 56 1,000 0,05020625 0,0980489 ! positive regulation of organelle organization GO:0010638 100 56 1,000 0,05020625 0,09796938 ! muscle fiber development GO:0048747 112 57 1,000 0,0518181 0,1010327 ! lipid modification GO:0030258 97 57 1,000 0,0518181 0,10095089 ! regulation of phospholipase activity GO:0010517 106 57 1,000 0,0518181 0,10086921 ! regulation of intracellular transport GO:0032386 101 57 1,000 0,0518181 0,10078767 ! maintenance of location GO:0051235 118 57 1,000 0,0518181 0,10070626 ! positive regulation of lipase activity GO:0060193 108 58 1,000 0,0534483 0,10379065 ! DNA catabolic process GO:0006308 86 59 1,000 0,05509657 0,10690512 ! establishment of organelle localization GO:0051656 109 59 1,000 0,05509657 0,10681897 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,05622583 0,10892058 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,05622583 0,10883295 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,05622583 0,10874546 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,05622583 0,10865812 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,05622583 0,10857091 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,05622583 0,10848385 ! phosphate transport GO:0006817 19 9 0,000 0,05622583 0,10839692 ! reproductive behavior GO:0019098 19 9 0,000 0,05622583 0,10831013 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,05622583 0,10822349 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,05622583 0,10813698 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05622583 0,1080506 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,05622583 0,10796437 ! GTP metabolic process GO:0046039 9 9 0,000 0,05622583 0,10787827 ! RNA methylation GO:0001510 15 9 0,000 0,05622583 0,10779232 ! elastic fiber assembly GO:0048251 15 9 0,000 0,05622583 0,10770649 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,05622583 0,10762081 ! artery development GO:0060840 24 9 0,000 0,05622583 0,10753526 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,05622583 0,10744985 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,05622583 0,10736457 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,05622583 0,10727943 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,05622583 0,10719442 ! chemosensory behavior GO:0007635 20 9 0,000 0,05622583 0,10710955 ! microtubule bundle formation GO:0001578 21 9 0,000 0,05622583 0,10702481 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,05622583 0,1069402 ! leukocyte degranulation GO:0043299 16 9 0,000 0,05622583 0,10685573 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,05622583 0,10677139 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,05622583 0,10668719 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,05622583 0,10660312 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,05622583 0,10651918 ! protein targeting to ER GO:0045047 22 9 0,000 0,05622583 0,10643537 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,05622583 0,1063517 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,05622583 0,10626815 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05622583 0,10618474 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,05622583 0,10610146 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,05622583 0,1060183 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05622583 0,10593528 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,05622583 0,10585239 ! mannose metabolic process GO:0006013 13 9 0,000 0,05622583 0,10576963 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,05622583 0,105687 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,05622583 0,10560449 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,05622583 0,10552212 ! receptor clustering GO:0043113 18 9 0,000 0,05622583 0,10543987 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,05622583 0,10535775 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,05622583 0,10527576 ! ruffle organization GO:0031529 15 9 0,000 0,05622583 0,1051939 ! retinol metabolic process GO:0042572 18 9 0,000 0,05622583 0,10511217 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,05622583 0,10503056 ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,05622583 0,10494907 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,05622583 0,10486772 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,05622583 0,10478649 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,05622583 0,10470538 ! segment specification GO:0007379 13 9 0,000 0,05622583 0,10462441 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,05622583 0,10454355 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,05622583 0,10446282 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,05622583 0,10438222 ! response to amine stimulus GO:0014075 13 9 0,000 0,05622583 0,10430174 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,05622583 0,10422138 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,05622583 0,10414115 ! erythrocyte development GO:0048821 15 9 0,000 0,05622583 0,10406104 ! gas homeostasis GO:0033483 16 9 0,000 0,05622583 0,10398106 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,05622583 0,1039012 ! renal water homeostasis GO:0003091 14 9 0,000 0,05622583 0,10382146 ! postreplication repair GO:0006301 22 9 0,000 0,05622583 0,10374184 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,05622583 0,10366234 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,05622583 0,10358297 ! icosanoid secretion GO:0032309 15 9 0,000 0,05622583 0,10350372 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,05622583 0,10342458 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,05622583 0,10334557 ! regulation of cell division GO:0051302 15 9 0,000 0,05622583 0,10326668 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,05622583 0,10318791 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,05622583 0,10310927 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,05622583 0,10303074 ! sterol catabolic process GO:0016127 11 9 0,000 0,05622583 0,10295233 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,05622583 0,10287404 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,05622583 0,10279586 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,05622583 0,10271781 GO:0002820|negative regulation of adaptive immune response, ! musculoskeletal movement GO:0050881 14 9 0,000 0,05622583 0,10263988 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,05622583 0,10256206 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,05622583 0,10248436 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,05622583 0,10240678 ! purine base metabolic process GO:0006144 21 9 0,000 0,05622583 0,10232932 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,05622583 0,10225197 ! pigment granule transport GO:0051904 17 9 0,000 0,05622583 0,10217474 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,05622583 0,10209763 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,05622583 0,10202063 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,05622583 0,10194375 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05622583 0,10186699 ! mitochondrion localization GO:0051646 15 9 0,000 0,05622583 0,10179034 ! regulation of neurotransmitter levels GO:0001505 97 60 1,000 0,0567626 0,10268482 ! DNA damage response, signal transduction GO:0042770 128 60 1,000 0,0567626 0,10260767 ! viral reproductive process GO:0022415 126 62 1,000 0,06014678 0,1086435 ! regulation of lipid metabolic process GO:0019216 115 63 1,000 0,06186435 0,11166214 ! steroid hormone receptor signaling pathway GO:0030518 129 63 1,000 0,06186435 0,11157844 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,06227567 0,11223615 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,06227567 0,11215214 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,06227567 0,11206826 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,06227567 0,1119845 ! synapsis GO:0007129 13 10 0,000 0,06227567 0,11190086 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,06227567 0,11181736 ! N-glycan processing GO:0006491 20 10 0,000 0,06227567 0,11173397 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,06227567 0,11165071 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,06227567 0,11156758 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,06227567 0,11148457 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,06227567 0,11140168 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 0,000 0,06227567 0,11131891 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,06227567 0,11123627 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,06227567 0,11115375 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,06227567 0,11107136 ! androgen metabolic process GO:0008209 17 10 0,000 0,06227567 0,11098908 ! phospholipid efflux GO:0033700 16 10 0,000 0,06227567 0,11090693 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,06227567 0,11082489 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,06227567 0,11074298 ! lung alveolus development GO:0048286 26 10 0,000 0,06227567 0,11066119 ! pathogenesis GO:0009405 13 10 0,000 0,06227567 0,11057953 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06227567 0,11049798 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,06227567 0,11041655 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,06227567 0,11033524 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,06227567 0,11025405 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,06227567 0,11017298 ! endoderm development GO:0007492 16 10 0,000 0,06227567 0,11009203 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,06227567 0,1100112 ! arginine catabolic process GO:0006527 13 10 0,000 0,06227567 0,10993049 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,06227567 0,1098499 ! proline metabolic process GO:0006560 13 10 0,000 0,06227567 0,10976942 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,06227567 0,10968906 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,06227567 0,10960882 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,06227567 0,1095287 ! V(D)J recombination GO:0033151 28 10 0,000 0,06227567 0,10944869 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,06227567 0,1093688 ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,06227567 0,10928903 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,06227567 0,10920937 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,06227567 0,10912983 ! multicellular organism growth GO:0035264 18 10 0,000 0,06227567 0,10905041 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,06227567 0,1089711 ! epithelial cell development GO:0002064 20 10 0,000 0,06227567 0,1088919 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,06227567 0,10881282 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,06227567 0,10873386 ! macroautophagy GO:0016236 17 10 0,000 0,06227567 0,10865501 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,06227567 0,10857627 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,06227567 0,10849765 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,06227567 0,10841914 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,06227567 0,10834075 ! copper ion homeostasis GO:0055070 13 10 0,000 0,06227567 0,10826247 ! regulation of bone resorption GO:0045124 25 10 0,000 0,06227567 0,1081843 ! brain morphogenesis GO:0048854 23 10 0,000 0,06227567 0,10810625 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,06227567 0,1080283 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,06227567 0,10795047 ! blastoderm segmentation GO:0007350 18 10 0,000 0,06227567 0,10787276 ! response to dsRNA GO:0043331 20 10 0,000 0,06227567 0,10779515 ! DNA ligation GO:0006266 19 10 0,000 0,06227567 0,10771765 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,06227567 0,10764027 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,06227567 0,107563 ! melanosome localization GO:0032400 16 10 0,000 0,06227567 0,10748584 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,06227567 0,10740879 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,06227567 0,10733185 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,06227567 0,10725502 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,06227567 0,1071783 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,06227567 0,10710169 ! mRNA cleavage GO:0006379 17 10 0,000 0,06227567 0,10702518 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,06227567 0,10694879 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06227567 0,10687251 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,06227567 0,10679633 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,06227567 0,10672027 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,06227567 0,10664431 ! salivary gland development GO:0007431 27 10 0,000 0,06227567 0,10656846 ! prophase GO:0051324 15 10 0,000 0,06227567 0,10649272 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,06227567 0,10641709 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,06227567 0,10634156 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,06227567 0,10626614 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,06227567 0,10619083 ! midbrain development GO:0030901 13 10 0,000 0,06227567 0,10611562 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,06227567 0,10604052 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,06227567 0,10596553 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,06227567 0,10589064 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,06227567 0,10581586 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,06227567 0,10574118 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,06227567 0,10566661 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,06227567 0,10559215 ! detection of calcium ion GO:0005513 23 10 0,000 0,06227567 0,10551779 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,06227567 0,10544353 ! cerebellar cortex development GO:0021695 15 10 0,000 0,06227567 0,10536938 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,06227567 0,10529533 ! activation of innate immune response GO:0002218 12 10 0,000 0,06227567 0,10522139 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,06227567 0,10514755 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,06227567 0,10507381 ! establishment of cell polarity GO:0030010 16 10 0,000 0,06227567 0,10500018 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,06227567 0,10492665 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,06227567 0,10485322 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 1,000 0,06359854 0,10700566 ! secondary metabolic process GO:0019748 116 66 1,000 0,06711563 0,11284431 ! developmental maturation GO:0021700 116 66 1,000 0,06711563 0,11276551 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,06828692 0,11465341 ! respiratory burst GO:0045730 17 11 0,000 0,06828692 0,11457345 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,06828692 0,11449361 ! neuron fate specification GO:0048665 17 11 0,000 0,06828692 0,11441388 ! telencephalon cell migration GO:0022029 20 11 0,000 0,06828692 0,11433426 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,06828692 0,11425475 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,06828692 0,11417535 ! thyroid gland development GO:0030878 26 11 0,000 0,06828692 0,11409606 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,06828692 0,11401689 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,06828692 0,11393782 ! response to pain GO:0048265 24 11 0,000 0,06828692 0,11385886 ! T cell proliferation GO:0042098 26 11 0,000 0,06828692 0,11378001 ! blood vessel remodeling GO:0001974 29 11 0,000 0,06828692 0,11370127 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,06828692 0,11362264 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,06828692 0,11354411 ! bone resorption GO:0045453 16 11 0,000 0,06828692 0,1134657 ! ventral spinal cord development GO:0021517 21 11 0,000 0,06828692 0,11338739 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,06828692 0,1133092 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,06828692 0,1132311 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,06828692 0,11315312 ! melanocyte differentiation GO:0030318 21 11 0,000 0,06828692 0,11307525 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,06828692 0,11299748 ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,06828692 0,11291982 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,06828692 0,11284226 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,06828692 0,11276481 ! lipid digestion GO:0044241 18 11 0,000 0,06828692 0,11268747 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,06828692 0,11261023 ! UV protection GO:0009650 19 11 0,000 0,06828692 0,1125331 ! adult heart development GO:0007512 14 11 0,000 0,06828692 0,11245608 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,06828692 0,11237916 ! temperature homeostasis GO:0001659 17 11 0,000 0,06828692 0,11230235 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,06828692 0,11222564 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,06828692 0,11214903 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,06828692 0,11207253 ! regulation of organ growth GO:0046620 13 11 0,000 0,06828692 0,11199614 ! pigment granule localization GO:0051875 20 11 0,000 0,06828692 0,11191985 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,06828692 0,11184366 ! vasoconstriction GO:0042310 18 11 0,000 0,06828692 0,11176757 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,06828692 0,11169159 ! embryonic axis specification GO:0000578 18 11 0,000 0,06828692 0,11161572 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,06828692 0,11153994 ! snRNA metabolic process GO:0016073 24 11 0,000 0,06828692 0,11146427 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,06828692 0,1113887 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,06828692 0,11131323 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,06828692 0,11123787 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,06828692 0,11116261 ! zymogen activation GO:0031638 15 11 0,000 0,06828692 0,11108745 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,06828692 0,11101239 ! nucleosome positioning GO:0016584 15 11 0,000 0,06828692 0,11093743 ! regulation of isotype switching GO:0045191 22 11 0,000 0,06828692 0,11086257 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,06828692 0,11078782 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,06828692 0,11071316 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,06828692 0,11063861 ! acid secretion GO:0046717 18 11 0,000 0,06828692 0,11056415 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,06828692 0,1104898 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,06828692 0,11041555 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,06828692 0,11034139 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,06828692 0,11026734 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,06828692 0,11019338 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! cholesterol efflux GO:0033344 19 11 0,000 0,06828692 0,11011953 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,06828692 0,11004577 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,06828692 0,10997211 ! germ cell migration GO:0008354 25 11 0,000 0,06828692 0,10989855 ! embryonic gut development GO:0048566 15 11 0,000 0,06828692 0,10982509 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,06828692 0,10975173 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,06828692 0,10967846 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,06828692 0,10960529 ! defense response to fungus GO:0050832 13 11 0,000 0,06828692 0,10953222 ! lysogeny GO:0030069 21 11 0,000 0,06828692 0,10945925 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,06828692 0,10938637 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,06828692 0,10931359 ! lamellipodium assembly GO:0030032 20 11 0,000 0,06828692 0,10924091 ! nucleus localization GO:0051647 19 11 0,000 0,06828692 0,10916833 ! regulation of synapse organization GO:0050807 17 11 0,000 0,06828692 0,10909584 ! regulation of cellular response to stress GO:0080135 128 67 1,000 0,06889798 0,10999903 ! activation of MAPK activity GO:0000187 115 67 1,000 0,06889798 0,10992608 ! chromosome segregation GO:0007059 113 67 1,000 0,06889798 0,10985324 ! positive regulation of T cell activation GO:0050870 109 67 1,000 0,06889798 0,10978049 ! amino acid transport GO:0006865 125 68 1,000 0,07069583 0,11257059 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 1,000 0,07069583 0,11249614 ! viral reproduction GO:0016032 134 68 1,000 0,07069583 0,11242179 ! regulation of lipase activity GO:0060191 130 68 1,000 0,07069583 0,11234753 ! coenzyme biosynthetic process GO:0009108 102 69 1,000 0,07250892 0,11515278 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,07425984 0,11785565 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,07425984 0,11777796 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,07425984 0,11770038 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,07425984 0,11762289 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,07425984 0,11754551 ! cartilage condensation GO:0001502 20 12 0,000 0,07425984 0,11746822 ! mating GO:0007618 17 12 0,000 0,07425984 0,11739104 ! protein complex disassembly GO:0043241 27 12 0,000 0,07425984 0,11731397 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,07425984 0,11723699 ! regulation of cell projection assembly GO:0060491 30 12 0,000 0,07425984 0,11716011 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 0,000 0,07425984 0,11708334 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,07425984 0,11700666 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,07425984 0,11693009 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,07425984 0,11685361 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,07425984 0,11677724 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,07425984 0,11670096 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,07425984 0,11662478 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,07425984 0,11654871 ! drug transport GO:0015893 16 12 0,000 0,07425984 0,11647273 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,07425984 0,11639685 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,07425984 0,11632107 ! polyamine metabolic process GO:0006595 17 12 0,000 0,07425984 0,11624539 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,07425984 0,11616981 ! forebrain cell migration GO:0021885 21 12 0,000 0,07425984 0,11609433 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,07425984 0,11601894 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,07425984 0,11594365 ! entry into host cell GO:0030260 32 12 0,000 0,07425984 0,11586846 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! monoamine transport GO:0015844 18 12 0,000 0,07425984 0,11579337 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07425984 0,11571837 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,07425984 0,11564348 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,07425984 0,11556867 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,07425984 0,11549397 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,07425984 0,11541936 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,07425984 0,11534485 ! protein homotetramerization GO:0051289 21 12 0,000 0,07425984 0,11527043 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,07425984 0,11519611 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,07425984 0,11512189 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,07425984 0,11504776 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,07425984 0,11497373 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,07425984 0,11489979 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,07425984 0,11482594 ! fucose catabolic process GO:0019317 22 12 0,000 0,07425984 0,1147522 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,07425984 0,11467854 ! histone methylation GO:0016571 26 12 0,000 0,07425984 0,11460498 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,07425984 0,11453152 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,07425984 0,11445815 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,07425984 0,11438487 ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,07425984 0,11431169 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,07425984 0,1142386 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,07425984 0,1141656 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,07425984 0,1140927 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,07425984 0,11401989 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,07425984 0,11394717 ! response to cold GO:0009409 17 12 0,000 0,07425984 0,11387455 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,07425984 0,11380202 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,07425984 0,11372958 ! humoral immune response GO:0006959 109 71 1,000 0,07617973 0,1165957 ! B cell activation GO:0042113 160 71 1,000 0,07617973 0,11652158 ! regulation of MAPKKK cascade GO:0043408 142 71 1,000 0,07617973 0,11644755 ! regulation of caspase activity GO:0043281 122 72 1,000 0,07803694 0,11921071 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,07803694 0,11913507 ! carbohydrate transport GO:0008643 110 72 1,000 0,07803694 0,11905953 ! axon guidance GO:0007411 139 73 1,000 0,07990833 0,12183741 ! cGMP metabolic process GO:0046068 18 13 0,000 0,08019466 0,12219655 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,08019466 0,12211921 ! regulation of chemokine production GO:0032642 18 13 0,000 0,08019466 0,12204197 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,08019466 0,12196483 GO:0000725|recombinational repair, ! peroxisomal transport GO:0043574 24 13 0,000 0,08019466 0,12188778 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,08019466 0,12181083 ! lipid localization GO:0010876 28 13 0,000 0,08019466 0,12173398 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,08019466 0,12165722 ! organelle fusion GO:0048284 32 13 0,000 0,08019466 0,12158056 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,08019466 0,121504 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,08019466 0,12142754 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,08019466 0,12135117 ! endocrine pancreas development GO:0031018 22 13 0,000 0,08019466 0,12127489 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,08019466 0,12119872 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,08019466 0,12112263 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,08019466 0,12104665 ! methionine metabolic process GO:0006555 27 13 0,000 0,08019466 0,12097076 ! plasma membrane organization GO:0007009 24 13 0,000 0,08019466 0,12089496 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,08019466 0,12081926 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,08019466 0,12074365 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,08019466 0,12066814 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,08019466 0,12059272 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,08019466 0,1205174 ! response to X-ray GO:0010165 25 13 0,000 0,08019466 0,12044217 ! cytokine metabolic process GO:0042107 22 13 0,000 0,08019466 0,12036703 ! cellular carbohydrate catabolic process GO:0044275 15 13 0,000 0,08019466 0,12029199 ! exocrine system development GO:0035272 32 13 0,000 0,08019466 0,12021704 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,08019466 0,12014219 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,08019466 0,12006743 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,08019466 0,11999276 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,08019466 0,11991818 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,08019466 0,1198437 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,08019466 0,11976931 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,08019466 0,11969501 ! regulation of cellular pH GO:0030641 22 13 0,000 0,08019466 0,1196208 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,08019466 0,11954669 ! ribosome assembly GO:0042255 17 13 0,000 0,08019466 0,11947267 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,08019466 0,11939873 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,08019466 0,11932489 ! chromatin silencing GO:0006342 26 13 0,000 0,08019466 0,11925115 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,08019466 0,11917749 ! regulation of epidermis development GO:0045682 19 13 0,000 0,08019466 0,11910392 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,08019466 0,11903045 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,08019466 0,11895706 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,08019466 0,11888377 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,08019466 0,11881056 ! regulation of fatty acid oxidation GO:0046320 27 13 0,000 0,08019466 0,11873745 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,08019466 0,11866442 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,08019466 0,11859149 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,08019466 0,11851865 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,08019466 0,11844589 ! insulin secretion GO:0030073 23 13 0,000 0,08019466 0,11837322 ! actin filament polymerization GO:0030041 24 13 0,000 0,08019466 0,11830065 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,08019466 0,11822816 ! acrosome reaction GO:0007340 18 13 0,000 0,08019466 0,11815576 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,08179365 0,12043789 GO:0090046|regulation of transcription regulator activity, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,08179365 0,12036423 ! organelle localization GO:0051640 136 74 1,000 0,08179365 0,12029066 ! rhythmic process GO:0048511 128 75 1,000 0,08369264 0,12300825 ! rRNA transcription GO:0009303 25 14 0,000 0,08609163 0,12645694 ! lactation GO:0007595 26 14 0,000 0,08609163 0,12637979 ! reproductive cellular process GO:0048610 20 14 0,000 0,08609163 0,12630272 ! tRNA modification GO:0006400 20 14 0,000 0,08609163 0,12622576 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,08609163 0,12614888 ! regulation of S phase GO:0033261 23 14 0,000 0,08609163 0,1260721 ! water transport GO:0006833 21 14 0,000 0,08609163 0,12599542 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,08609163 0,12591883 ! non-recombinational repair GO:0000726 25 14 0,000 0,08609163 0,12584233 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,08609163 0,12576592 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,08609163 0,1256896 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,08609163 0,12561338 ! RNA polyadenylation GO:0043631 30 14 0,000 0,08609163 0,12553725 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,08609163 0,12546122 ! regulated secretory pathway GO:0045055 23 14 0,000 0,08609163 0,12538527 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,08609163 0,12530942 ! arginine metabolic process GO:0006525 17 14 0,000 0,08609163 0,12523366 ! regulation of heart rate GO:0002027 24 14 0,000 0,08609163 0,12515799 ! organic alcohol transport GO:0015850 29 14 0,000 0,08609163 0,12508241 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,08609163 0,12500692 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,08609163 0,12493152 ! embryo implantation GO:0007566 30 14 0,000 0,08609163 0,12485622 ! neutral amino acid transport GO:0015804 26 14 0,000 0,08609163 0,124781 ! L-amino acid transport GO:0015807 30 14 0,000 0,08609163 0,12470588 ! stem cell development GO:0048864 43 14 0,000 0,08609163 0,12463085 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,08609163 0,1245559 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,08609163 0,12448105 ! cerebellum development GO:0021549 21 14 0,000 0,08609163 0,12440629 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,08609163 0,12433161 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,08609163 0,12425703 ! cofactor transport GO:0051181 26 14 0,000 0,08609163 0,12418253 ! NADP metabolic process GO:0006739 24 14 0,000 0,08609163 0,12410813 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,08609163 0,12403381 ! intestinal absorption GO:0050892 25 14 0,000 0,08609163 0,12395959 ! cAMP biosynthetic process GO:0006171 23 14 0,000 0,08609163 0,12388545 ! oxygen transport GO:0015671 21 14 0,000 0,08609163 0,1238114 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,08609163 0,12373744 ! male genitalia development GO:0030539 24 14 0,000 0,08609163 0,12366356 ! regulation of RNA stability GO:0043487 32 14 0,000 0,08609163 0,12358978 ! regulation of axon extension GO:0030516 37 14 0,000 0,08609163 0,12351608 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,08609163 0,12344247 ! protein oligomerization GO:0051259 139 78 1,000 0,08946919 0,12820898 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,09142041 0,13092709 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,09195099 0,13160862 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,09195099 0,13153037 ! superoxide anion generation GO:0042554 20 15 0,000 0,09195099 0,13145222 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,09195099 0,13137416 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,09195099 0,13129619 ! copper ion transport GO:0006825 20 15 0,000 0,09195099 0,13121832 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,09195099 0,13114054 ! sulfate transport GO:0008272 23 15 0,000 0,09195099 0,13106285 ! response to cAMP GO:0051591 22 15 0,000 0,09195099 0,13098525 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,09195099 0,13090774 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,09195099 0,13083033 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,09195099 0,13075301 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,09195099 0,13067578 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,09195099 0,13059864 ! response to hexose stimulus GO:0009746 22 15 0,000 0,09195099 0,13052159 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,09195099 0,13044463 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,09195099 0,13036776 ! pituitary gland development GO:0021983 29 15 0,000 0,09195099 0,13029098 ! vesicle coating GO:0006901 33 15 0,000 0,09195099 0,1302143 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,09195099 0,1301377 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,09195099 0,13006119 ! regulation of exocytosis GO:0017157 22 15 0,000 0,09195099 0,12998478 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,09195099 0,12990845 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,09195099 0,12983221 ! regulation of vasodilation GO:0042312 26 15 0,000 0,09195099 0,12975606 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,09195099 0,12968 ! histone deacetylation GO:0016575 20 15 0,000 0,09195099 0,12960404 ! mRNA splice site selection GO:0006376 38 15 0,000 0,09195099 0,12952815 ! tissue regeneration GO:0042246 26 15 0,000 0,09195099 0,12945236 ! water homeostasis GO:0030104 27 15 0,000 0,09195099 0,12937666 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,09195099 0,12930105 ! muscle maintenance GO:0046716 26 15 0,000 0,09195099 0,12922552 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 0,000 0,09195099 0,12915008 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,09195099 0,12907473 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,09195099 0,12899947 ! dopamine metabolic process GO:0042417 35 15 0,000 0,09195099 0,12892429 ! heme biosynthetic process GO:0006783 29 15 0,000 0,09195099 0,12884921 ! cell killing GO:0001906 29 15 0,000 0,09195099 0,12877421 ! detection of bacterium GO:0016045 18 15 0,000 0,09195099 0,1286993 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,09195099 0,12862447 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,09195099 0,12854973 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,09195099 0,12847508 ! peptide hormone processing GO:0016486 23 15 0,000 0,09195099 0,12840052 ! muscle cell differentiation GO:0042692 159 80 1,000 0,09338408 0,13032604 ! cellular lipid catabolic process GO:0044242 134 80 1,000 0,09338408 0,13025049 ! response to drug GO:0042493 143 82 1,000 0,09734782 0,13570038 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,09777298 0,13621412 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,09777298 0,13613529 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,09777298 0,13605656 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,09777298 0,13597791 ! bone remodeling GO:0046849 27 16 0,000 0,09777298 0,13589936 ! filopodium assembly GO:0046847 32 16 0,000 0,09777298 0,13582089 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,09777298 0,13574252 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,09777298 0,13566424 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,09777298 0,13558605 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,09777298 0,13550794 ! startle response GO:0001964 28 16 0,000 0,09777298 0,13542993 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,09777298 0,13535201 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,09777298 0,13527417 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,09777298 0,13519643 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,09777298 0,13511878 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,09777298 0,13504121 ! protein polyubiquitination GO:0000209 34 16 0,000 0,09777298 0,13496373 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,09777298 0,13488635 ! response to osmotic stress GO:0006970 25 16 0,000 0,09777298 0,13480905 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,09777298 0,13473184 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,09777298 0,13465472 ! fructose metabolic process GO:0006000 25 16 0,000 0,09777298 0,13457768 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,09777298 0,13450074 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,09777298 0,13442388 ! intermediate filament-based process GO:0045103 32 16 0,000 0,09777298 0,13434711 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,09777298 0,13427043 ! negative regulation of immune response GO:0050777 35 16 0,000 0,09777298 0,13419383 ! axon cargo transport GO:0008088 43 16 0,000 0,09777298 0,13411733 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,09777298 0,13404091 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,09777298 0,13396457 ! positive regulation of protein import into nucleus GO:0042307 30 16 0,000 0,09777298 0,13388833 ! DNA replication initiation GO:0006270 27 16 0,000 0,09777298 0,13381217 ! neuron recognition GO:0008038 35 16 0,000 0,09777298 0,13373609 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,09777298 0,13366011 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,09777298 0,13358421 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,09777298 0,13350839 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,09777298 0,13343267 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,09777298 0,13335702 GO:0046466|membrane lipid catabolic process, ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,09777298 0,13328147 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,09777298 0,133206 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,09777298 0,13313061 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,09777298 0,13305531 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,09777298 0,1329801 ! response to unfolded protein GO:0006986 131 85 1,000 0,10338094 0,14052799 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,10338094 0,14044865 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,10355783 0,14060956 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,10355783 0,14053025 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,10355783 0,14045104 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,10355783 0,14037191 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,10355783 0,14029287 ! endothelial cell migration GO:0043542 28 17 0,000 0,10355783 0,14021392 ! inositol metabolic process GO:0006020 28 17 0,000 0,10355783 0,14013506 ! gene silencing by RNA GO:0031047 36 17 0,000 0,10355783 0,14005629 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,10355783 0,13997761 ! glial cell development GO:0021782 27 17 0,000 0,10355783 0,13989901 ! adult walking behavior GO:0007628 33 17 0,000 0,10355783 0,13982051 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,10355783 0,13974209 ! heart looping GO:0001947 30 17 0,000 0,10355783 0,13966376 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,10355783 0,13958551 ! myoblast differentiation GO:0045445 45 17 0,000 0,10355783 0,13950736 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,10355783 0,13942929 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,10355783 0,13935131 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,10355783 0,13927342 ! glycine metabolic process GO:0006544 28 17 0,000 0,10355783 0,13919561 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,10355783 0,13911789 ! NAD metabolic process GO:0019674 29 17 0,000 0,10355783 0,13904026 ! membrane budding GO:0006900 37 17 0,000 0,10355783 0,13896271 ! DNA integration GO:0015074 29 17 0,000 0,10355783 0,13888525 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,10355783 0,13880788 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,10355783 0,13873059 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 0,000 0,10355783 0,13865339 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,10355783 0,13857627 ! genitalia development GO:0048806 30 17 0,000 0,10355783 0,13849925 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,10355783 0,1384223 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,10355783 0,13834544 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,10355783 0,13826867 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,10355783 0,13819198 ! steroid catabolic process GO:0006706 31 17 0,000 0,10355783 0,13811538 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,10355783 0,13803886 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,10355783 0,13796243 ! gas transport GO:0015669 25 17 0,000 0,10355783 0,13788608 ! organic cation transport GO:0015695 31 17 0,000 0,10355783 0,13780981 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,10355783 0,13773363 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,10355783 0,13765754 ! microspike assembly GO:0030035 36 17 0,000 0,10355783 0,13758153 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,10355783 0,1375056 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,10355783 0,13742975 ! amine transport GO:0015837 155 86 1,000 0,10541441 0,13981646 ! regulation of protein transport GO:0051223 154 87 1,000 0,10745871 0,1424494 GO:0070201|regulation of establishment of protein localization, ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,10930578 0,14481812 ! neuron maturation GO:0042551 42 18 0,000 0,10930578 0,14473842 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,10930578 0,14465881 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,10930578 0,14457928 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,10930578 0,14449984 ! protein amino acid ADP-ribosylation GO:0006471 33 18 0,000 0,10930578 0,14442049 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,10930578 0,14434123 ! memory GO:0007613 31 18 0,000 0,10930578 0,14426205 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,10930578 0,14418296 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,10930578 0,14410395 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,10930578 0,14402503 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,10930578 0,1439462 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,10930578 0,14386746 ! glutamine metabolic process GO:0006541 29 18 0,000 0,10930578 0,1437888 ! response to retinoic acid GO:0032526 26 18 0,000 0,10930578 0,14371023 ! response to fungus GO:0009620 21 18 0,000 0,10930578 0,14363174 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,10930578 0,14355334 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,10930578 0,14347502 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,10930578 0,14339679 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,10930578 0,14331864 ! vitamin transport GO:0051180 27 18 0,000 0,10930578 0,14324058 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,10930578 0,14316261 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,10930578 0,14308472 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,10930578 0,14300691 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,10930578 0,14292919 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,10930578 0,14285156 ! cellular respiration GO:0045333 135 88 1,000 0,10951363 0,14304549 ! regulation of DNA binding GO:0051101 155 88 1,000 0,10951363 0,14296787 ! regulation of cell morphogenesis GO:0022604 215 89 1,000 0,11157895 0,14558511 ! protein secretion GO:0009306 39 19 0,000 0,11501707 0,14998974 ! positive regulation of translation GO:0045727 30 19 0,000 0,11501707 0,14990849 ! negative regulation of defense response GO:0031348 25 19 0,000 0,11501707 0,14982732 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,11501707 0,14974625 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,11501707 0,14966526 ! skin development GO:0043588 36 19 0,000 0,11501707 0,14958436 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,11501707 0,14950355 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,11501707 0,14942282 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,11501707 0,14934218 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,11501707 0,14926163 ! bile acid metabolic process GO:0008206 29 19 0,000 0,11501707 0,14918117 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,11501707 0,14910079 ! cerebral cortex development GO:0021987 36 19 0,000 0,11501707 0,1490205 ! pigmentation during development GO:0048066 41 19 0,000 0,11501707 0,14894029 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,11501707 0,14886018 GO:0030968|endoplasmic reticulum unfolded protein response, ! response to vitamin A GO:0033189 27 19 0,000 0,11501707 0,14878014 ! heme metabolic process GO:0042168 36 19 0,000 0,11501707 0,1487002 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,11501707 0,14862034 ! plasma membrane fusion GO:0045026 28 19 0,000 0,11501707 0,14854056 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,11501707 0,14846087 ! peptide cross-linking GO:0018149 37 19 0,000 0,11501707 0,14838127 ! protein export from nucleus GO:0006611 36 19 0,000 0,11501707 0,14830175 ! heart process GO:0003015 30 19 0,000 0,11501707 0,14822232 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,11501707 0,14814297 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,11501707 0,14806371 ! visual learning GO:0008542 36 19 0,000 0,11501707 0,14798453 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,11501707 0,14790543 ! cell-cell junction organization GO:0045216 35 19 0,000 0,11501707 0,14782642 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,11501707 0,1477475 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,11501707 0,14766866 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,11501707 0,1475899 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,11501707 0,14751123 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,11501707 0,14743264 ! cilium assembly GO:0042384 37 19 0,000 0,11501707 0,14735414 ! peptide hormone secretion GO:0030072 31 19 0,000 0,11501707 0,14727571 ! cofactor biosynthetic process GO:0051188 139 91 1,000 0,11573992 0,14812247 ! carbohydrate biosynthetic process GO:0016051 141 93 1,000 0,11993993 0,15341598 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,11993993 0,15333447 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,12069192 0,15421389 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,12069192 0,15413204 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,12069192 0,15405027 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,12069192 0,15396859 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 0,000 0,12069192 0,153887 ! cAMP metabolic process GO:0046058 36 20 0,000 0,12069192 0,15380549 ! response to vitamin GO:0033273 31 20 0,000 0,12069192 0,15372407 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,12069192 0,15364273 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,12069192 0,15356148 ! C21-steroid hormone metabolic process GO:0008207 33 20 0,000 0,12069192 0,15348032 ! retinoid metabolic process GO:0001523 32 20 0,000 0,12069192 0,15339924 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,12069192 0,15331825 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,12069192 0,15323734 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,12069192 0,15315652 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,12069192 0,15307578 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,12069192 0,15299513 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,12069192 0,15291457 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,12069192 0,15283408 ! body fluid secretion GO:0007589 31 20 0,000 0,12069192 0,15275369 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,12069192 0,15267338 ! peptide secretion GO:0002790 35 20 0,000 0,12069192 0,15259315 ! stem cell differentiation GO:0048863 53 20 0,000 0,12069192 0,152513 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,12069192 0,15243295 ! regulation of fatty acid metabolic process GO:0019217 38 20 0,000 0,12069192 0,15235297 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,12069192 0,15227308 ! sensory perception of pain GO:0019233 30 20 0,000 0,12069192 0,15219327 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,12069192 0,15211355 ! diencephalon development GO:0021536 34 20 0,000 0,12069192 0,15203391 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,12069192 0,15195435 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,12069192 0,15187488 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,12069192 0,15179548 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,12069192 0,15171618 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,12069192 0,15163695 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,12069192 0,15155781 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,12069192 0,15147875 ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,12069192 0,15139977 ! actin filament-based movement GO:0030048 43 20 0,000 0,12069192 0,15132088 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,12069192 0,15124206 ! negative regulation of translation GO:0017148 29 20 0,000 0,12069192 0,15116333 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,12069192 0,15108468 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,12069192 0,15100612 ! transcription initiation GO:0006352 153 94 1,000 0,12205405 0,152631 ! regulation of cell killing GO:0031341 42 21 0,000 0,12633057 0,15789681 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,12633057 0,15781483 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,12633057 0,15773293 ! hormone secretion GO:0046879 38 21 0,000 0,12633057 0,15765112 ! glycerol metabolic process GO:0006071 34 21 0,000 0,12633057 0,15756939 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,12633057 0,15748775 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,12633057 0,15740619 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,12633057 0,15732472 ! axis specification GO:0009798 38 21 0,000 0,12633057 0,15724333 ! smooth muscle contraction GO:0006939 46 21 0,000 0,12633057 0,15716202 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,12633057 0,1570808 ! cytolysis GO:0019835 24 21 0,000 0,12633057 0,15699967 ! vasodilation GO:0042311 39 21 0,000 0,12633057 0,15691861 ! cholesterol biosynthetic process GO:0006695 37 21 0,000 0,12633057 0,15683764 ! regulation of vasoconstriction GO:0019229 39 21 0,000 0,12633057 0,15675676 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,12633057 0,15667596 ! DNA modification GO:0006304 34 21 0,000 0,12633057 0,15659524 ! collagen fibril organization GO:0030199 59 21 0,000 0,12633057 0,1565146 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,12633057 0,15643405 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 0,000 0,12633057 0,15635358 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,12633057 0,15627319 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,12633057 0,15619288 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,12633057 0,15611266 ! collagen catabolic process GO:0030574 28 21 0,000 0,12633057 0,15603252 ! sperm-egg recognition GO:0035036 21 21 0,000 0,12633057 0,15595246 ! protein ubiquitination GO:0016567 217 97 1,000 0,12845044 0,15848808 ! response to virus GO:0009615 160 98 1,000 0,13059991 0,1610576 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,13193325 0,16261854 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,13193325 0,16253528 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,13193325 0,1624521 ! microtubule-based transport GO:0010970 54 22 0,000 0,13193325 0,162369 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,13193325 0,16228599 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,13193325 0,16220306 ! keratinization GO:0031424 28 22 0,000 0,13193325 0,16212022 ! calcium-independent cell-cell adhesion GO:0016338 30 22 0,000 0,13193325 0,16203747 ! sensory perception of taste GO:0050909 28 22 0,000 0,13193325 0,16195479 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,13193325 0,16187221 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,13193325 0,1617897 ! vacuolar transport GO:0007034 36 22 0,000 0,13193325 0,16170728 ! lysosome organization GO:0007040 41 22 0,000 0,13193325 0,16162495 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,13193325 0,1615427 ! fucose metabolic process GO:0006004 39 22 0,000 0,13193325 0,16146053 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,13193325 0,16137844 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 0,000 0,13193325 0,16129644 GO:0060415|muscle tissue morphogenesis, ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,13193325 0,16121452 ! positive regulation of intracellular transport GO:0032388 37 22 0,000 0,13193325 0,16113269 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,13193325 0,16105094 ! sarcomere organization GO:0045214 30 22 0,000 0,13193325 0,16096927 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,13193325 0,16088768 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,13193325 0,16080618 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,13193325 0,16072476 ! protein stabilization GO:0050821 39 22 0,000 0,13193325 0,16064342 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,13750018 0,1673371 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,13750018 0,1672525 ! viral genome replication GO:0019079 41 23 0,000 0,13750018 0,16716798 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,13750018 0,16708356 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,13750018 0,16699921 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,13750018 0,16691495 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,13750018 0,16683078 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,13750018 0,16674669 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,13750018 0,16666269 ! visual behavior GO:0007632 42 23 0,000 0,13750018 0,16657877 ! regulation of DNA recombination GO:0000018 48 23 0,000 0,13750018 0,16649494 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,13750018 0,16641119 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! peroxisome organization GO:0007031 37 23 0,000 0,13750018 0,16632752 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,13750018 0,16624394 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,13750018 0,16616044 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,13750018 0,16607703 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,13750018 0,1659937 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,13750018 0,16591045 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,13750018 0,16582729 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,13750018 0,16574421 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,13750018 0,16566121 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,13750018 0,1655783 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,13750018 0,16549547 ! fatty acid transport GO:0015908 44 23 0,000 0,13750018 0,16541272 ! platelet activation GO:0030168 37 23 0,000 0,13750018 0,16533006 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,13750018 0,16524747 ! hormone transport GO:0009914 40 23 0,000 0,13750018 0,16516497 ! cell-cell recognition GO:0009988 25 23 0,000 0,13750018 0,16508256 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,13750018 0,16500022 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,13750018 0,16491797 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,13750018 0,1648358 ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,13750018 0,16475371 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,1430316 0,17129618 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,1430316 0,17121096 GO:0016444|somatic cell DNA recombination, ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,1430316 0,17112582 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,1430316 0,17104077 ! vesicle docking GO:0048278 47 24 0,000 0,1430316 0,1709558 ! spinal cord development GO:0021510 47 24 0,000 0,1430316 0,17087092 ! vacuole organization GO:0007033 43 24 0,000 0,1430316 0,17078612 ! digestive system process GO:0022600 39 24 0,000 0,1430316 0,1707014 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,1430316 0,17061677 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,1430316 0,17053223 ! membrane depolarization GO:0051899 39 24 0,000 0,1430316 0,17044776 ! pentose metabolic process GO:0019321 35 24 0,000 0,1430316 0,17036338 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,1430316 0,17027908 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,1430316 0,17019487 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,1430316 0,17011074 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,1430316 0,17002669 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,1430316 0,16994273 ! regulation of amine transport GO:0051952 40 24 0,000 0,1430316 0,16985885 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,14852773 0,17629882 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,14852773 0,17621189 ! protein amino acid alkylation GO:0008213 53 25 0,000 0,14852773 0,17612504 GO:0006479|protein amino acid methylation, ! sperm motility GO:0030317 31 25 0,000 0,14852773 0,17603828 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,14852773 0,1759516 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,14852773 0,17586501 ! receptor metabolic process GO:0043112 46 25 0,000 0,14852773 0,17577851 ! chromosome condensation GO:0030261 45 25 0,000 0,14852773 0,17569209 ! response to starvation GO:0042594 42 25 0,000 0,14852773 0,17560575 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,14852773 0,1755195 ! neural crest cell development GO:0014032 54 25 0,000 0,14852773 0,17543334 GO:0014033|neural crest cell differentiation, ! regulation of insulin secretion GO:0050796 37 25 0,000 0,14852773 0,17534726 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,14852773 0,17526126 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,14852773 0,17517535 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,14852773 0,17508952 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,14852773 0,17500377 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,14852773 0,17491811 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,14852773 0,17483254 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,14852773 0,17474705 ! neural tube closure GO:0001843 49 25 0,000 0,14852773 0,17466164 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,14852773 0,17457631 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,15398878 0,18090674 ! embryonic pattern specification GO:0009880 44 26 0,000 0,15398878 0,18081845 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,15398878 0,18073025 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,15398878 0,18064213 ! initiation of viral infection GO:0019059 57 26 0,000 0,15398878 0,1805541 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,15398878 0,18046615 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,15398878 0,18037829 ! tube lumen formation GO:0035148 50 26 0,000 0,15398878 0,18029052 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,15398878 0,18020283 ! regulation of transcription factor import into nucleus GO:0042990 54 26 0,000 0,15398878 0,18011522 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,15398878 0,1800277 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,15398878 0,17994027 ! regulation of cellular ketone metabolic process GO:0010565 44 26 0,000 0,15398878 0,17985292 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,15398878 0,17976565 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,15398878 0,17967847 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,15398878 0,17959138 ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,15398878 0,17950437 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,15398878 0,17941744 ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,15398878 0,1793306 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,15398878 0,17924384 ! neuron fate commitment GO:0048663 48 27 0,000 0,159415 0,18547025 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,159415 0,18538061 ! positive regulation of cell projection organization GO:0031346 58 27 0,000 0,159415 0,18529105 ! iron ion transport GO:0006826 59 27 0,000 0,159415 0,18520158 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,159415 0,1851122 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,159415 0,1850229 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,159415 0,18493369 ! fat cell differentiation GO:0045444 50 27 0,000 0,159415 0,18484457 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,159415 0,18475553 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,159415 0,18466658 ! autophagy GO:0006914 41 27 0,000 0,159415 0,18457771 ! primary neural tube formation GO:0014020 51 27 0,000 0,159415 0,18448893 ! base-excision repair GO:0006284 41 27 0,000 0,159415 0,18440023 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 0,000 0,159415 0,18431162 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,159415 0,18422309 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,159415 0,18413465 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,159415 0,1840463 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,16480658 0,19017968 ! circadian rhythm GO:0007623 50 28 0,000 0,16480658 0,19008852 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,16480658 0,18999743 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,16480658 0,18990644 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,16480658 0,18981553 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,16480658 0,18972471 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,16480658 0,18963398 ! lipid oxidation GO:0034440 43 28 0,000 0,16480658 0,18954333 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,16480658 0,18945277 ! translational initiation GO:0006413 65 29 0,000 0,17016377 0,19551768 ! negative regulation of protein complex assembly GO:0031333 59 29 0,000 0,17016377 0,19542436 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,17016377 0,19533112 ! regulation of pH GO:0006885 43 29 0,000 0,17016377 0,19523797 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,17016377 0,19514491 ! catechol metabolic process GO:0009712 54 29 0,000 0,17016377 0,19505194 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,17016377 0,19495906 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,17016377 0,19486627 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,17016377 0,19477356 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,17016377 0,19468095 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,17016377 0,19458842 ! cell fate determination GO:0001709 60 29 0,000 0,17016377 0,19449598 ! sterol biosynthetic process GO:0016126 52 29 0,000 0,17016377 0,19440362 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,17016377 0,19431136 ! regulation of coagulation GO:0050818 46 29 0,000 0,17016377 0,19421918 ! phenol metabolic process GO:0018958 55 30 0,000 0,17548677 0,2001997 ! zinc ion transport GO:0006829 45 30 0,000 0,17548677 0,20010482 ! membrane docking GO:0022406 61 30 0,000 0,17548677 0,20001003 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,17548677 0,19991532 ! regulation of innate immune response GO:0045088 51 30 0,000 0,17548677 0,19982071 ! acute-phase response GO:0006953 49 30 0,000 0,17548677 0,19972619 ! myofibril assembly GO:0030239 47 30 0,000 0,17548677 0,19963176 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,17548677 0,19953741 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,17548677 0,19944316 ! phospholipid transport GO:0015914 51 30 0,000 0,17548677 0,19934899 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,17548677 0,19925491 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 48 30 0,000 0,17548677 0,19916093 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,1807758 0,20506675 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,1807758 0,20497011 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,1807758 0,20487356 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,1807758 0,20477711 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,1807758 0,20468074 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,1807758 0,20458446 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,1807758 0,20448828 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,1807758 0,20439219 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,1807758 0,20429618 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,1807758 0,20420027 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,1807758 0,20410444 ! peptide transport GO:0015833 55 31 0,000 0,1807758 0,20400871 ! mesoderm formation GO:0001707 69 31 0,000 0,1807758 0,20391307 ! natural killer cell activation GO:0030101 45 31 0,000 0,1807758 0,20381751 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,1807758 0,20372205 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,1807758 0,20362667 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,1807758 0,20353139 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,1807758 0,20343619 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,18603108 0,20925235 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,18603108 0,20915456 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,18603108 0,20905687 ! cholesterol transport GO:0030301 56 32 0,000 0,18603108 0,20895928 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,18603108 0,20886177 ! spliceosome assembly GO:0000245 67 32 0,000 0,18603108 0,20876435 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,18603108 0,20866702 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,18603108 0,20856979 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,18603108 0,20847264 ! regulation of protein import into nucleus GO:0042306 63 32 0,000 0,18603108 0,20837559 ! muscle cell development GO:0055001 49 32 0,000 0,18603108 0,20827863 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,18603108 0,20818175 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,18603108 0,20808497 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,18603108 0,20798828 ! gene silencing GO:0016458 65 32 0,000 0,18603108 0,20789167 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,19125281 0,2136278 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,19125281 0,21352866 ! protein targeting to membrane GO:0006612 68 33 0,000 0,19125281 0,21342962 ! ceramide metabolic process GO:0006672 64 33 0,000 0,19125281 0,21333068 ! formation of primary germ layer GO:0001704 72 33 0,000 0,19125281 0,21323182 ! sterol transport GO:0015918 57 33 0,000 0,19125281 0,21313306 ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,19125281 0,21303438 ! adult locomotory behavior GO:0008344 59 33 0,000 0,19125281 0,2129358 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,19125281 0,21283731 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,19644123 0,21851021 ! glial cell differentiation GO:0010001 63 34 0,000 0,19644123 0,21840924 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,19644123 0,21830836 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,19644123 0,21820757 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,19644123 0,21810687 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,19644123 0,21800627 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,19644123 0,21790576 ! spermatid development GO:0007286 63 34 0,000 0,19644123 0,21780534 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,19644123 0,21770502 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,19644123 0,21760478 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,20159653 0,22321272 ! negative regulation of secretion GO:0051048 63 35 0,000 0,20159653 0,22311005 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,20159653 0,22300747 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,20159653 0,22290498 ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,20159653 0,22280259 ! cytokine production GO:0001816 59 35 0,000 0,20159653 0,22270029 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,20159653 0,22259809 ! neural tube formation GO:0001841 67 35 0,000 0,20159653 0,22249598 ! vesicle localization GO:0051648 64 35 0,000 0,20159653 0,22239397 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,20671892 0,22794029 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,20671892 0,22783588 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,20671892 0,22773156 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,20671892 0,22762733 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,20671892 0,2275232 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,20671892 0,22741917 ! regulation of proteolysis GO:0030162 72 36 0,000 0,20671892 0,22731523 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 0,000 0,20671892 0,22721138 ! hormone biosynthetic process GO:0042446 57 36 0,000 0,20671892 0,22710764 ! RNA export from nucleus GO:0006405 56 37 0,000 0,21180862 0,23259313 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,21180862 0,23248702 ! establishment or maintenance of cell polarity GO:0007163 83 37 0,000 0,21180862 0,232381 ! actomyosin structure organization GO:0031032 62 37 0,000 0,21180862 0,23227509 ! organic anion transport GO:0015711 68 37 0,000 0,21180862 0,23216927 ! tissue remodeling GO:0048771 76 37 0,000 0,21180862 0,23206354 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,21180862 0,23195791 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,21180862 0,23185238 ! cyclic nucleotide metabolic process GO:0009187 63 37 0,000 0,21180862 0,23174695 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,21180862 0,23164161 GO:0015986|ATP synthesis coupled proton transport, ! glycogen metabolic process GO:0005977 61 37 0,000 0,21180862 0,23153636 ! spermatid differentiation GO:0048515 66 37 0,000 0,21180862 0,23143122 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,21686583 0,23684938 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,21686583 0,23674192 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,21686583 0,23663455 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,21686583 0,23652728 ! lipid homeostasis GO:0055088 67 38 0,000 0,21686583 0,23642011 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,21686583 0,23631304 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,21686583 0,23620606 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,21686583 0,23609918 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,21686583 0,2359924 ! glucan metabolic process GO:0044042 62 38 0,000 0,21686583 0,23588571 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,22189076 0,24124228 ! ion transmembrane transport GO:0034220 66 39 0,000 0,22189076 0,24113332 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,22189076 0,24102446 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,22189076 0,24091569 ! RNA modification GO:0009451 57 39 0,000 0,22189076 0,24080702 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,22189076 0,24069846 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,22688362 0,2460036 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,22688362 0,24589278 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,22688362 0,24578207 ! feeding behavior GO:0007631 59 40 0,000 0,22688362 0,24567146 ! negative regulation of binding GO:0051100 72 40 0,000 0,22688362 0,24556095 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,22688362 0,24545053 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,22688362 0,24534022 ! maintenance of protein location GO:0045185 91 40 0,000 0,22688362 0,24523 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,2318446 0,25047962 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,2318446 0,25036719 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,2318446 0,25025487 ! gliogenesis GO:0042063 88 41 0,000 0,2318446 0,25014265 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,2318446 0,25003053 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,2318446 0,24991851 ! polyol metabolic process GO:0019751 66 41 0,000 0,2318446 0,24980659 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,23677391 0,25500359 ! regulation of tube size GO:0035150 71 42 0,000 0,23677391 0,2548895 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,23677391 0,25477551 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,23677391 0,25466161 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,23677391 0,25454782 ! regulation of protein secretion GO:0050708 71 42 0,000 0,23677391 0,25443414 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,24167175 0,25958136 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,24167175 0,25946552 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,24167175 0,2593498 ! neural tube development GO:0021915 77 43 0,000 0,24167175 0,25923417 ! striated muscle contraction GO:0006941 77 43 0,000 0,24167175 0,25911865 ! phagocytosis GO:0006909 90 43 0,000 0,24167175 0,25900323 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,24167175 0,25888791 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,24653833 0,26398363 ! double-strand break repair GO:0006302 81 44 0,000 0,24653833 0,2638662 ! biopolymer methylation GO:0043414 84 44 0,000 0,24653833 0,26374887 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,24653833 0,26363165 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,25137383 0,268683 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,25137383 0,26856369 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,25137383 0,26844449 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,25137383 0,2683254 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,25137383 0,2682064 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,25137383 0,26808752 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,25137383 0,26796874 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,25617846 0,27296961 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,25617846 0,27284877 ! positive regulation of protein transport GO:0051222 72 46 0,000 0,25617846 0,27272804 ! response to calcium ion GO:0051592 81 47 0,000 0,26095242 0,27768753 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,26095242 0,27756477 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,26095242 0,27744212 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,26095242 0,27731957 ! methylation GO:0032259 90 47 0,000 0,26095242 0,27719714 ! protein homooligomerization GO:0051260 76 47 0,000 0,26095242 0,27707481 ! Notch signaling pathway GO:0007219 96 48 0,000 0,26569589 0,2819869 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,26569589 0,28186257 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,26569589 0,28173835 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,26569589 0,28161423 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,27040907 0,28648359 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,27040907 0,28635749 ! regulation of ion transport GO:0043269 77 49 0,000 0,27040907 0,28623151 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,27040907 0,28610564 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,27040907 0,28597988 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,27040907 0,28585423 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,27040907 0,28572869 ! regulation of cell projection organization GO:0031344 121 50 0,000 0,27509216 0,29054949 ! neuromuscular process GO:0050905 99 50 0,000 0,27509216 0,290422 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,27509216 0,29029462 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,27509216 0,29016735 ! viral infectious cycle GO:0019058 99 51 0,000 0,27974534 0,29494622 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,27974534 0,29481703 ! excretion GO:0007588 83 51 0,000 0,27974534 0,29468795 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,27974534 0,29455899 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,27974534 0,29443013 ! membrane fusion GO:0006944 110 52 0,000 0,28436881 0,29916543 ! amino acid activation GO:0043038 92 52 0,000 0,28436881 0,29903468 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 76 53 0,000 0,28896275 0,30373279 ! RNA catabolic process GO:0006401 93 53 0,000 0,28896275 0,30360016 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,28896275 0,30346764 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 0,000 0,28896275 0,30333524 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,28896275 0,30320295 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,28896275 0,30307078 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,29352735 0,3077241 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,29352735 0,30759007 ! cell recognition GO:0008037 85 54 0,000 0,29352735 0,30745616 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,29352735 0,30732237 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,29352735 0,30718869 ! chloride transport GO:0006821 90 55 0,000 0,2980628 0,3117996 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,2980628 0,3116641 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,2980628 0,31152871 ! gastrulation GO:0007369 112 55 0,000 0,2980628 0,31139344 ! RNA elongation GO:0006354 79 55 0,000 0,2980628 0,31125829 ! nuclear export GO:0051168 97 55 0,000 0,2980628 0,31112325 ! regulation of actin filament length GO:0030832 105 56 0,000 0,30256928 0,31569024 ! sensory perception of smell GO:0007608 80 56 0,000 0,30256928 0,3155534 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,30256928 0,31541668 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,30256928 0,31528007 ! proton transport GO:0015992 94 56 0,000 0,30256928 0,31514359 ! hydrogen transport GO:0006818 97 58 0,000 0,31149608 0,32430098 ! regulation of endocytosis GO:0030100 91 58 0,000 0,31149608 0,32416071 ! adult behavior GO:0030534 99 58 0,000 0,31149608 0,32402057 ! positive regulation of secretion GO:0051047 95 59 0,000 0,31591676 0,32847698 ! regulation of cellular component size GO:0032535 109 59 0,000 0,31591676 0,32833509 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,31591676 0,32819332 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,31591676 0,32805167 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,31591676 0,32791015 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,3203092 0,33232598 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,32467359 0,3367089 ! regulation of protein complex assembly GO:0043254 117 61 0,000 0,32467359 0,33656383 ! mesoderm development GO:0007498 119 61 0,000 0,32467359 0,33641889 ! tRNA processing GO:0008033 89 61 0,000 0,32467359 0,33627407 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,32467359 0,33612937 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,32901009 0,34047238 ! nucleoside monophosphate metabolic process GO:0009123 107 63 0,000 0,3333189 0,344783 ! cell redox homeostasis GO:0045454 102 64 0,000 0,33760017 0,34906146 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,33760017 0,34891152 ! single fertilization GO:0007338 75 64 0,000 0,33760017 0,34876171 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,3418541 0,3530047 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,3418541 0,35285326 ! embryonic limb morphogenesis GO:0030326 125 65 0,000 0,3418541 0,35270195 GO:0035113|embryonic appendage morphogenesis, ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,34608084 0,35690977 ! fatty acid biosynthetic process GO:0006633 124 66 0,000 0,34608084 0,35675686 ! extracellular matrix organization GO:0030198 133 66 0,000 0,34608084 0,35660407 ! cell projection assembly GO:0030031 120 66 0,000 0,34608084 0,35645141 ! cellular hormone metabolic process GO:0034754 113 67 0,000 0,35028058 0,36062263 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,35028058 0,36046838 ! adaptive immune response GO:0002250 119 67 0,000 0,35028058 0,36031427 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,35028058 0,36016029 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,35445349 0,36429521 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,35445349 0,36413966 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,35445349 0,36398425 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,35859973 0,36808488 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,35859973 0,36792791 ! antigen processing and presentation GO:0019882 104 69 0,000 0,35859973 0,36777108 ! appendage morphogenesis GO:0035107 135 70 0,000 0,36271948 0,3718377 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 136 71 0,000 0,36681291 0,37587387 GO:0060173|limb development, ! regulation of immune effector process GO:0002697 137 71 0,000 0,36681291 0,37571386 ! acute inflammatory response GO:0002526 113 72 0,000 0,37088017 0,37971817 ! regulation of blood pressure GO:0008217 125 73 0,000 0,37492145 0,38369247 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,37492145 0,38352934 ! fertilization GO:0009566 90 73 0,000 0,37492145 0,38336634 ! transition metal ion transport GO:0000041 126 74 0,000 0,3789369 0,38730764 ! neurotransmitter transport GO:0006836 123 74 0,000 0,3789369 0,38714318 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,3789369 0,38697885 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,3789369 0,38681467 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,38292669 0,39072163 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,38292669 0,390556 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,38689097 0,39443207 ! defense response to bacterium GO:0042742 89 76 0,000 0,38689097 0,39426501 ! steroid biosynthetic process GO:0006694 131 76 0,000 0,38689097 0,39409809 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,39082993 0,39794194 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,39082993 0,39777361 ! blood coagulation GO:0007596 146 78 0,000 0,3947437 0,40158704 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,3947437 0,40141731 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,39863246 0,40520055 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,39863246 0,40502944 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,40249637 0,40878272 ! protein import into nucleus GO:0006606 158 80 0,000 0,40249637 0,40861023 ! inorganic anion transport GO:0015698 138 80 0,000 0,40249637 0,4084379 ! digestion GO:0007586 112 81 0,000 0,40633557 0,41215994 ! intracellular protein transmembrane transport GO:0065002 153 81 0,000 0,40633557 0,41198626 ! nuclear import GO:0051170 161 81 0,000 0,40633557 0,41181271 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,41015023 0,41550377 ! cholesterol metabolic process GO:0008203 136 82 0,000 0,41015023 0,4153289 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,41015023 0,41515417 ! regulation of lyase activity GO:0051339 160 83 0,000 0,41394051 0,4188145 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,41770656 0,42244724 ! hemostasis GO:0007599 158 84 0,000 0,41770656 0,42226974 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,41770656 0,42209239 ! nucleosome assembly GO:0006334 122 85 0,000 0,42144853 0,42569486 ! amine biosynthetic process GO:0009309 138 86 0,000 0,42516658 0,42927016 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,42516658 0,4290901 ! chromatin assembly GO:0031497 124 86 0,000 0,42516658 0,42891019 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,42886086 0,43245567 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! protein localization in nucleus GO:0034504 176 87 0,000 0,42886086 0,4322745 ! regulation of neurological system process GO:0031644 148 88 0,000 0,43253152 0,4357918 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,43253152 0,43560939 ! cellular defense response GO:0006968 114 89 0,000 0,4361787 0,43909873 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,43980257 0,44256169 ! protein-DNA complex assembly GO:0065004 130 90 0,000 0,43980257 0,44237667 ! sterol metabolic process GO:0016125 152 91 0,000 0,44340327 0,44581206 ! nucleosome organization GO:0034728 138 92 0,000 0,44698094 0,44922145 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,44698094 0,44903388 ! vitamin metabolic process GO:0006766 139 92 0,000 0,44698094 0,44884647 ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,45053573 0,45222736 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,45406779 0,45558262 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,4610643 0,46240963 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,4610643 0,46221696 ! positive regulation of immune response GO:0050778 156 96 0,000 0,4610643 0,46202445 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,46452902 0,4653026 ! hormone metabolic process GO:0042445 157 97 0,000 0,46452902 0,46510896 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,46797159 0,46836092 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,47139214 0,47158815 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,47139214 0,47139214