pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6421-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! negative regulation of phosphorylation GO:0042326 41 23 5,000 8,046E-09 1,851E-05 ! positive regulation of glycolysis GO:0045821 11 5 3,000 1,015E-08 1,167E-05 ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 5,000 1,067E-08 8,179E-06 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 5,000 1,396E-08 8,027E-06 GO:0045936|negative regulation of phosphate metabolic process, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 3,000 3,029E-08 1,394E-05 ! inner ear receptor cell differentiation GO:0060113 30 16 4,000 5,525E-08 2,118E-05 ! mechanoreceptor differentiation GO:0042490 32 18 4,000 1,072E-07 3,522E-05 ! induction of positive chemotaxis GO:0050930 14 8 3,000 1,399E-07 4,022E-05 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 3,000 1,399E-07 3,575E-05 ! positive regulation of glucose metabolic process GO:0010907 15 9 3,000 2,505E-07 5,761E-05 ! regulation of glycolysis GO:0006110 15 9 3,000 2,505E-07 5,237E-05 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 3,000 4,153E-07 7,959E-05 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of positive chemotaxis GO:0050926 17 11 3,000 6,491E-07 1,148E-04 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of endothelial cell proliferation GO:0001938 18 11 3,000 6,491E-07 1,066E-04 ! positive regulation of cellular catabolic process GO:0031331 22 12 3,000 9,686E-07 1,485E-04 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 3,000 9,686E-07 1,392E-04 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of catabolic process GO:0009896 40 28 4,000 1,165E-06 1,576E-04 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 3,000 1,392E-06 1,778E-04 ! negative regulation of protein kinase activity GO:0006469 99 57 5,000 2,395E-06 2,9E-04 ! negative regulation of kinase activity GO:0033673 100 58 5,000 2,657E-06 3,056E-04 ! lung development GO:0030324 94 59 5,000 2,942E-06 3,222E-04 ! regulation of hormone biosynthetic process GO:0046885 7 5 2,000 3,045E-06 3,183E-04 ! regulation of glucose metabolic process GO:0010906 22 16 3,000 3,487E-06 3,487E-04 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 3,000 3,487E-06 3,342E-04 ! negative regulation of transferase activity GO:0051348 105 61 5,000 3,585E-06 3,298E-04 ! respiratory tube development GO:0030323 99 62 5,000 3,947E-06 3,492E-04 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 5,000 4,339E-06 3,696E-04 ! respiratory system development GO:0060541 100 64 5,000 4,761E-06 3,911E-04 ! positive regulation of protein ubiquitination GO:0031398 8 6 2,000 6,06E-06 4,806E-04 ! regulation of protein export from nucleus GO:0046825 6 6 2,000 6,06E-06 4,646E-04 ! N-terminal protein amino acid acetylation GO:0006474 7 6 2,000 6,06E-06 4,496E-04 ! ER overload response GO:0006983 7 6 2,000 6,06E-06 4,355E-04 ! regulation of epithelial cell proliferation GO:0050678 71 39 4,000 6,426E-06 4,479E-04 ! induction of apoptosis by intracellular signals GO:0008629 67 40 4,000 7,305E-06 4,941E-04 ! inner ear development GO:0048839 57 40 4,000 7,305E-06 4,8E-04 ! regulation of carbohydrate metabolic process GO:0006109 28 19 3,000 7,31E-06 4,67E-04 GO:0010675|regulation of cellular carbohydrate metabolic process, ! positive regulation of phosphorylation GO:0042327 102 70 5,000 8,054E-06 5,007E-04 ! positive regulation of locomotion GO:0040017 35 20 3,000 9,089E-06 5,501E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of phosphorus metabolic process GO:0010562 107 72 5,000 9,492E-06 5,598E-04 GO:0045937|positive regulation of phosphate metabolic process, ! G1/S transition of mitotic cell cycle GO:0000082 87 43 4,000 1,051E-05 6,045E-04 ! regulation of gene-specific transcription GO:0032583 69 43 4,000 1,051E-05 5,898E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 2,000 1,055E-05 5,778E-04 ! regulation of chemotaxis GO:0050920 36 21 3,000 1,117E-05 5,974E-04 ! regulation of fibroblast proliferation GO:0048145 35 22 3,000 1,358E-05 7,098E-04 ! regulation of behavior GO:0050795 38 22 3,000 1,358E-05 6,941E-04 ! histone modification GO:0016570 68 46 4,000 1,473E-05 7,365E-04 ! covalent chromatin modification GO:0016569 75 47 4,000 1,639E-05 8,022E-04 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 2,000 1,68E-05 8,049E-04 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 2,000 1,68E-05 7,885E-04 ! regulation of cellular catabolic process GO:0031329 36 24 3,000 1,952E-05 8,979E-04 ! regulation of endothelial cell proliferation GO:0001936 46 24 3,000 1,952E-05 8,803E-04 ! cartilage development GO:0051216 70 49 4,000 2,016E-05 8,917E-04 ! ear development GO:0043583 72 50 4,000 2,228E-05 9,668E-04 ! positive regulation of cell migration GO:0030335 92 51 4,000 2,457E-05 1,046E-03 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 2,000 2,507E-05 1,048E-03 ! regulation of hormone metabolic process GO:0032350 15 9 2,000 2,507E-05 1,03E-03 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 2,000 2,507E-05 1,012E-03 ! embryonic placenta development GO:0001892 12 9 2,000 2,507E-05 9,943E-04 ! cell cycle arrest GO:0007050 150 86 5,000 2,644E-05 1,031E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 3,000 2,717E-05 1,042E-03 ! negative regulation of protein modification process GO:0031400 50 26 3,000 2,717E-05 1,025E-03 ! regulation of B cell proliferation GO:0030888 15 10 2,000 3,564E-05 1,322E-03 ! peptide or protein amino-terminal blocking GO:0018409 14 10 2,000 3,564E-05 1,301E-03 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 2,000 3,564E-05 1,281E-03 ! positive regulation of cell motion GO:0051272 99 56 4,000 3,888E-05 1,376E-03 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 2,000 4,876E-05 1,699E-03 ! chondrocyte differentiation GO:0002062 17 11 2,000 4,876E-05 1,674E-03 ! regulation of vascular endothelial growth factor production GO:0010574 19 11 2,000 4,876E-05 1,649E-03 ! histone deacetylation GO:0016575 13 11 2,000 4,876E-05 1,625E-03 ! negative regulation of glucose import GO:0046325 14 11 2,000 4,876E-05 1,602E-03 GO:0010829|negative regulation of glucose transport, ! negative regulation of mast cell proliferation GO:0070667 17 11 2,000 4,876E-05 1,58E-03 GO:0042130|negative regulation of T cell proliferation, ! positive regulation of gene-specific transcription GO:0043193 47 31 3,000 5,571E-05 1,78E-03 ! auditory receptor cell differentiation GO:0042491 25 12 2,000 6,469E-05 2,038E-03 ! histone acetylation GO:0016573 23 12 2,000 6,469E-05 2,011E-03 ! peptidyl-lysine modification GO:0018205 18 12 2,000 6,469E-05 1,984E-03 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 4,000 7,431E-05 2,249E-03 ! N-terminal protein amino acid modification GO:0031365 18 13 2,000 8,368E-05 2,5E-03 ! regulation of monooxygenase activity GO:0032768 26 13 2,000 8,368E-05 2,468E-03 ! regulation of intracellular protein transport GO:0033157 59 35 3,000 9,078E-05 2,643E-03 ! regulation of erythrocyte differentiation GO:0045646 27 14 2,000 1,06E-04 3,047E-03 ! regulation of catabolic process GO:0009894 106 70 4,000 1,142E-04 3,243E-03 ! response to hypoxia GO:0001666 132 72 4,000 1,306E-04 3,663E-03 ! regulation of protein ubiquitination GO:0031396 19 15 2,000 1,318E-04 3,653E-03 ! embryonic forelimb morphogenesis GO:0035115 17 15 2,000 1,318E-04 3,609E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 2,000 1,318E-04 3,567E-03 ! regulation of the force of heart contraction GO:0002026 21 15 2,000 1,318E-04 3,525E-03 ! negative regulation of leukocyte proliferation GO:0070664 25 15 2,000 1,318E-04 3,485E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! negative regulation of transport GO:0051051 116 73 4,000 1,394E-04 3,644E-03 ! cell growth GO:0016049 61 39 3,000 1,396E-04 3,609E-03 ! response to oxygen levels GO:0070482 137 74 4,000 1,487E-04 3,801E-03 ! positive regulation of response to external stimulus GO:0032103 65 40 3,000 1,543E-04 3,901E-03 ! negative regulation of growth GO:0045926 123 75 4,000 1,585E-04 3,963E-03 ! protein amino acid deacetylation GO:0006476 20 16 2,000 1,614E-04 3,992E-03 ! protein amino acid acetylation GO:0006473 28 16 2,000 1,614E-04 3,95E-03 ! neutrophil chemotaxis GO:0030593 21 16 2,000 1,614E-04 3,908E-03 ! regulation of T cell differentiation GO:0045580 59 41 3,000 1,701E-04 4,076E-03 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 3,000 1,871E-04 4,436E-03 ! positive regulation of protein modification process GO:0031401 107 78 4,000 1,908E-04 4,477E-03 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 2,000 1,95E-04 4,531E-03 ! forelimb morphogenesis GO:0035136 19 17 2,000 1,95E-04 4,486E-03 ! inactivation of MAPK activity GO:0000188 27 17 2,000 1,95E-04 4,442E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 1,95E-04 4,398E-03 ! negative regulation of intracellular transport GO:0032387 29 17 2,000 1,95E-04 4,355E-03 ! regulation of mast cell proliferation GO:0070666 64 44 3,000 2,245E-04 4,965E-03 ! apoptotic mitochondrial changes GO:0008637 29 18 2,000 2,329E-04 5,102E-03 ! regulation of glucose import GO:0046324 21 18 2,000 2,329E-04 5,053E-03 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 25 18 2,000 2,329E-04 5,006E-03 ! protein amino acid autophosphorylation GO:0046777 80 45 3,000 2,451E-04 5,22E-03 ! response to UV GO:0009411 75 46 3,000 2,671E-04 5,635E-03 ! positive regulation of fibroblast proliferation GO:0048146 27 19 2,000 2,752E-04 5,754E-03 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 2,000 2,752E-04 5,702E-03 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 2,752E-04 5,651E-03 ! sex determination GO:0007530 29 19 2,000 2,752E-04 5,601E-03 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 2,000 2,752E-04 5,552E-03 ! regulation of leukocyte proliferation GO:0070663 71 47 3,000 2,904E-04 5,808E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! interphase of mitotic cell cycle GO:0051329 156 86 4,000 3,014E-04 5,975E-03 ! regulation of lymphocyte differentiation GO:0045619 69 48 3,000 3,151E-04 6,195E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 3,222E-04 6,279E-03 ! positive regulation of inflammatory response GO:0050729 30 20 2,000 3,222E-04 6,227E-03 ! interphase GO:0051325 159 88 4,000 3,354E-04 6,428E-03 ! regulation of intracellular transport GO:0032386 78 49 3,000 3,413E-04 6,488E-03 ! protein amino acid acylation GO:0043543 37 21 2,000 3,74E-04 7,051E-03 ! dendrite development GO:0016358 35 21 2,000 3,74E-04 6,993E-03 ! response to endoplasmic reticulum stress GO:0034976 25 21 2,000 3,74E-04 6,937E-03 ! cellular response to extracellular stimulus GO:0031668 32 21 2,000 3,74E-04 6,881E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 3,984E-04 7,273E-03 ! vasculogenesis GO:0001570 33 22 2,000 4,309E-04 7,804E-03 ! protein tetramerization GO:0051262 39 22 2,000 4,309E-04 7,743E-03 ! peptidyl-amino acid modification GO:0018193 147 93 4,000 4,331E-04 7,721E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 4,534E-04 8,021E-03 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 4,534E-04 7,96E-03 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 1,000 4,534E-04 7,9E-03 ! embryonic hemopoiesis GO:0035162 10 5 1,000 4,534E-04 7,84E-03 ! microvillus organization GO:0032528 7 5 1,000 4,534E-04 7,782E-03 GO:0030033|microvillus assembly, ! neural tube patterning GO:0021532 6 5 1,000 4,534E-04 7,724E-03 ! positive regulation of chemokine production GO:0032722 7 5 1,000 4,534E-04 7,667E-03 ! regulation of respiratory burst GO:0060263 8 5 1,000 4,534E-04 7,611E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 4,534E-04 7,556E-03 ! response to oxidative stress GO:0006979 141 94 4,000 4,549E-04 7,528E-03 ! angiogenesis GO:0001525 149 95 4,000 4,776E-04 7,847E-03 ! myelination GO:0042552 35 23 2,000 4,931E-04 8,043E-03 ! ER-nuclear signaling pathway GO:0006984 27 23 2,000 4,931E-04 7,986E-03 ! cellular response to oxidative stress GO:0034599 33 23 2,000 4,931E-04 7,931E-03 ! negative regulation of cell development GO:0010721 56 24 2,000 5,607E-04 8,956E-03 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 39 24 2,000 5,607E-04 8,894E-03 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 4,000 5,77E-04 9,09E-03 ! negative regulation of lymphocyte activation GO:0051250 37 25 2,000 6,34E-04 9,92E-03 ! regulation of helicase activity GO:0051095 11 6 1,000 6,77E-04 0,01052122 ! male meiosis GO:0007140 7 6 1,000 6,77E-04 0,0104506 ! mRNA stabilization GO:0048255 15 6 1,000 6,77E-04 0,01038093 GO:0043489|RNA stabilization, ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 1,000 6,77E-04 0,01031219 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 6,77E-04 0,01024434 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 1,000 6,77E-04 0,01017739 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 1,000 6,77E-04 0,0101113 ! male sex determination GO:0030238 9 6 1,000 6,77E-04 0,01004606 ! gas homeostasis GO:0033483 11 6 1,000 6,77E-04 9,982E-03 ! regulation of interleukin-13 production GO:0032656 11 6 1,000 6,77E-04 9,918E-03 ! myeloid dendritic cell activation GO:0001773 10 6 1,000 6,77E-04 9,855E-03 GO:0043011|myeloid dendritic cell differentiation, ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 6,77E-04 9,793E-03 ! axonal fasciculation GO:0007413 9 6 1,000 6,77E-04 9,732E-03 ! midbrain development GO:0030901 6 6 1,000 6,77E-04 9,672E-03 ! negative regulation of axon extension GO:0030517 13 6 1,000 6,77E-04 9,612E-03 ! negative regulation of B cell activation GO:0050869 9 6 1,000 6,77E-04 9,553E-03 ! regulation of homeostatic process GO:0032844 105 60 3,000 7,417E-04 0,01040188 ! negative regulation of leukocyte activation GO:0002695 39 27 2,000 7,984E-04 0,01112887 ! negative regulation of protein transport GO:0051224 49 27 2,000 7,984E-04 0,01106183 ! negative regulation of cell growth GO:0030308 106 62 3,000 8,397E-04 0,01156434 ! negative regulation of MAP kinase activity GO:0043407 54 28 2,000 8,898E-04 0,01218125 ! ensheathment of neurons GO:0007272 43 28 2,000 8,898E-04 0,01210917 GO:0008366|axon ensheathment, ! placenta development GO:0001890 37 28 2,000 8,898E-04 0,01203794 ! regulation of B cell activation GO:0050864 42 28 2,000 8,898E-04 0,01196754 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 9,436E-04 0,01261796 ! microtubule bundle formation GO:0001578 8 7 1,000 9,436E-04 0,01254502 ! T-helper 1 type immune response GO:0042088 11 7 1,000 9,436E-04 0,01247292 ! hemoglobin metabolic process GO:0020027 10 7 1,000 9,436E-04 0,01240165 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 1,000 9,436E-04 0,01233118 ! synaptic transmission, glutamatergic GO:0035249 13 7 1,000 9,436E-04 0,01226152 ! protein heterooligomerization GO:0051291 10 7 1,000 9,436E-04 0,01219263 ! G1 DNA damage checkpoint GO:0031571 18 7 1,000 9,436E-04 0,01212452 ! B cell lineage commitment GO:0002326 17 7 1,000 9,436E-04 0,01205716 ! regulation of interleukin-10 production GO:0032653 11 7 1,000 9,436E-04 0,01199054 ! positive regulation of monooxygenase activity GO:0032770 11 7 1,000 9,436E-04 0,01192466 ! T cell lineage commitment GO:0002360 12 7 1,000 9,436E-04 0,0118595 ! response to tumor cell GO:0002347 12 7 1,000 9,436E-04 0,01179505 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 1,000 9,436E-04 0,01173129 ! negative regulation of cell size GO:0045792 108 64 3,000 9,464E-04 0,01170325 ! negative regulation of cell activation GO:0050866 44 30 2,000 1,092E-03 0,01342889 ! learning or memory GO:0007611 123 68 3,000 1,188E-03 0,01453434 ! leukocyte chemotaxis GO:0030595 43 31 2,000 1,203E-03 0,01463773 GO:0060326|cell chemotaxis, ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 1,253E-03 0,01516231 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 1,253E-03 0,01508293 ! L-phenylalanine metabolic process GO:0006558 8 8 1,000 1,253E-03 0,01500437 GO:0006559|L-phenylalanine catabolic process, ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 1,253E-03 0,01492663 ! regulation of vascular permeability GO:0043114 12 8 1,000 1,253E-03 0,01484969 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 1,253E-03 0,01477353 ! regulation of interleukin-4 production GO:0032673 16 8 1,000 1,253E-03 0,01469816 ! induction of an organ GO:0001759 11 8 1,000 1,253E-03 0,01462355 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 1,000 1,253E-03 0,01454969 ! regulation of embryonic development GO:0045995 16 8 1,000 1,253E-03 0,01447658 ! carbohydrate homeostasis GO:0033500 39 33 2,000 1,446E-03 0,01662465 GO:0042593|glucose homeostasis, ! androgen receptor signaling pathway GO:0030521 54 33 2,000 1,446E-03 0,01654194 ! regulation of developmental growth GO:0048638 13 9 1,000 1,603E-03 0,01825475 ! lung alveolus development GO:0048286 17 9 1,000 1,603E-03 0,01816483 ! negative regulation of striated muscle development GO:0045843 11 9 1,000 1,603E-03 0,01807578 ! motor axon guidance GO:0008045 14 9 1,000 1,603E-03 0,01798761 ! localization within membrane GO:0051668 15 9 1,000 1,603E-03 0,01790029 ! regulation of action potential in neuron GO:0019228 54 35 2,000 1,717E-03 0,01907885 ! regulation of protein transport GO:0051223 114 76 3,000 1,795E-03 0,01985038 GO:0070201|regulation of establishment of protein localization, ! tissue remodeling GO:0048771 62 36 2,000 1,864E-03 0,02051249 ! neural tube development GO:0021915 50 36 2,000 1,864E-03 0,02041481 ! response to xenobiotic stimulus GO:0009410 50 36 2,000 1,864E-03 0,02031806 ! negative regulation of muscle development GO:0048635 12 10 1,000 1,995E-03 0,02164543 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 1,000 1,995E-03 0,02154381 ! blood vessel remodeling GO:0001974 21 10 1,000 1,995E-03 0,02144314 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 1,000 1,995E-03 0,0213434 GO:0010812|negative regulation of cell-substrate adhesion, ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 1,995E-03 0,02124459 ! response to X-ray GO:0010165 16 10 1,000 1,995E-03 0,02114669 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 1,000 1,995E-03 0,02104968 ! regulation of bone resorption GO:0045124 24 10 1,000 1,995E-03 0,02095357 ! negative regulation of axonogenesis GO:0050771 23 10 1,000 1,995E-03 0,02085832 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 1,995E-03 0,02076394 ! developmental induction GO:0031128 13 10 1,000 1,995E-03 0,02067041 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell activation GO:0042110 134 79 3,000 2,07E-03 0,02134717 ! forebrain development GO:0030900 131 80 3,000 2,167E-03 0,02225426 ! regulation of T cell proliferation GO:0042129 58 38 2,000 2,181E-03 0,02229098 ! regulation of cell cycle process GO:0010564 122 81 3,000 2,268E-03 0,02308273 ! virus-host interaction GO:0019048 17 11 1,000 2,428E-03 0,02459757 ! regulation of mRNA processing GO:0050684 18 11 1,000 2,428E-03 0,02448969 ! regulation of intracellular pH GO:0051453 17 11 1,000 2,428E-03 0,02438275 ! nitric oxide metabolic process GO:0046209 14 11 1,000 2,428E-03 0,02427673 GO:0006809|nitric oxide biosynthetic process, ! regulation of leukocyte migration GO:0002685 24 11 1,000 2,428E-03 0,02417164 ! aromatic amino acid family catabolic process GO:0009074 13 11 1,000 2,428E-03 0,02406745 ! T cell differentiation GO:0030217 65 40 2,000 2,529E-03 0,02496248 ! regulation of myeloid cell differentiation GO:0045637 69 40 2,000 2,529E-03 0,0248558 ! JAK-STAT cascade GO:0007259 53 40 2,000 2,529E-03 0,02475003 ! positive regulation of MAP kinase activity GO:0043406 121 85 3,000 2,703E-03 0,02634767 ! regulation of protein localization GO:0032880 132 85 3,000 2,703E-03 0,02623649 ! epithelial cell differentiation GO:0030855 55 41 2,000 2,715E-03 0,02623757 ! negative regulation of cell projection organization GO:0031345 26 12 1,000 2,9E-03 0,02791054 ! cartilage condensation GO:0001502 18 12 1,000 2,9E-03 0,02779425 ! heart looping GO:0001947 15 12 1,000 2,9E-03 0,02767892 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 1,000 2,9E-03 0,02756454 ! tyrosine metabolic process GO:0006570 14 12 1,000 2,9E-03 0,02745111 ! cell-cell junction assembly GO:0007043 18 12 1,000 2,9E-03 0,02733861 ! response to gamma radiation GO:0010332 20 12 1,000 2,9E-03 0,02722702 ! regulation of mRNA stability GO:0043488 27 12 1,000 2,9E-03 0,02711634 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 2,9E-03 0,02700656 ! Wnt receptor signaling pathway GO:0016055 130 87 3,000 2,941E-03 0,02727806 ! leukocyte migration GO:0050900 60 43 2,000 3,112E-03 0,02874814 ! activation of caspase activity GO:0006919 65 43 2,000 3,112E-03 0,02863315 ! regulation of neurogenesis GO:0050767 153 89 3,000 3,193E-03 0,02925856 ! regulation of T cell activation GO:0050863 128 89 3,000 3,193E-03 0,02914246 ! regulation of action potential GO:0001508 71 44 2,000 3,324E-03 0,03021455 ! induction of apoptosis by extracellular signals GO:0008624 74 44 2,000 3,324E-03 0,0300956 ! regulation of inflammatory response GO:0050727 60 44 2,000 3,324E-03 0,02997758 ! leukocyte differentiation GO:0002521 143 90 3,000 3,324E-03 0,02986586 ! regulation of chemokine production GO:0032642 17 13 1,000 3,412E-03 0,03053877 ! negative regulation of protein import into nucleus GO:0042308 25 13 1,000 3,412E-03 0,03042041 ! regulation of cellular pH GO:0030641 20 13 1,000 3,412E-03 0,03030295 ! regulation of RNA stability GO:0043487 28 13 1,000 3,412E-03 0,0301864 ! regulation of axon extension GO:0030516 23 13 1,000 3,412E-03 0,03007075 ! positive regulation of cell cycle GO:0045787 77 45 2,000 3,543E-03 0,03110699 ! positive regulation of defense response GO:0031349 59 45 2,000 3,543E-03 0,03098871 ! cell fate commitment GO:0045165 141 92 3,000 3,598E-03 0,03134211 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 3,963E-03 0,03439969 ! cellular response to starvation GO:0009267 21 14 1,000 3,963E-03 0,03427037 ! negative regulation of microtubule depolymerization GO:0007026 31 14 1,000 3,963E-03 0,03414201 GO:0031114|regulation of microtubule depolymerization, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 3,963E-03 0,03401462 ! G1/S transition checkpoint GO:0031575 33 14 1,000 3,963E-03 0,03388817 ! synaptic transmission, cholinergic GO:0007271 21 14 1,000 3,963E-03 0,03376266 ! muscle maintenance GO:0046716 19 14 1,000 3,963E-03 0,03363807 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 3,963E-03 0,0335144 ! epithelial to mesenchymal transition GO:0001837 22 14 1,000 3,963E-03 0,03339164 ! negative regulation of immune system process GO:0002683 73 47 2,000 4,009E-03 0,03365612 ! regulation of response to external stimulus GO:0032101 139 96 3,000 4,189E-03 0,03503713 ! in utero embryonic development GO:0001701 147 96 3,000 4,189E-03 0,03491018 ! response to light stimulus GO:0009416 153 96 3,000 4,189E-03 0,03478415 ! positive regulation of caspase activity GO:0043280 72 48 2,000 4,256E-03 0,0352095 GO:0010952|positive regulation of peptidase activity, ! regulation of muscle contraction GO:0006937 69 48 2,000 4,256E-03 0,0350833 ! heart morphogenesis GO:0003007 65 48 2,000 4,256E-03 0,034958 ! regulation of DNA replication GO:0006275 75 48 2,000 4,256E-03 0,0348336 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 2,000 4,256E-03 0,03471007 ! positive regulation of cytokine production GO:0001819 73 48 2,000 4,256E-03 0,03458742 ! regulation of angiogenesis GO:0045765 94 49 2,000 4,511E-03 0,03653311 ! positive regulation of cell size GO:0045793 20 15 1,000 4,553E-03 0,03674289 ! negative regulation of cell cycle process GO:0010948 24 15 1,000 4,553E-03 0,03661442 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 1,000 4,553E-03 0,03648684 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 4,553E-03 0,03636015 ! neuron recognition GO:0008038 22 15 1,000 4,553E-03 0,03623434 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 1,000 4,553E-03 0,03610939 ! positive regulation of oxidoreductase activity GO:0051353 21 15 1,000 4,553E-03 0,03598531 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 4,553E-03 0,03586207 ! regulation of T-helper cell differentiation GO:0045622 23 15 1,000 4,553E-03 0,03573967 ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 4,553E-03 0,03561811 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 1,000 4,553E-03 0,03549737 ! regulation of translation GO:0006417 151 100 3,000 4,843E-03 0,03763478 ! activation of phospholipase C activity GO:0007202 87 51 2,000 5,049E-03 0,0390999 GO:0010863|positive regulation of phospholipase C activity, ! patterning of blood vessels GO:0001569 24 16 1,000 5,18E-03 0,03998203 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 1,000 5,18E-03 0,03984831 ! neural crest cell migration GO:0001755 24 16 1,000 5,18E-03 0,03971548 ! positive regulation of phospholipase activity GO:0010518 88 52 2,000 5,332E-03 0,04074149 ! aging GO:0007568 79 52 2,000 5,332E-03 0,04060658 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 1,000 5,845E-03 0,04436782 ! neuromuscular junction development GO:0007528 23 17 1,000 5,845E-03 0,04422187 ! peptidyl-serine modification GO:0018209 27 17 1,000 5,845E-03 0,04407688 ! cell-cell junction organization GO:0045216 25 17 1,000 5,845E-03 0,04393284 ! proximal/distal pattern formation GO:0009954 25 17 1,000 5,845E-03 0,04378973 ! aromatic compound catabolic process GO:0019439 22 17 1,000 5,845E-03 0,04364756 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 5,845E-03 0,0435063 ! regulation of phospholipase activity GO:0010517 90 54 2,000 5,926E-03 0,04396441 ! DNA catabolic process GO:0006308 67 54 2,000 5,926E-03 0,04382305 ! positive regulation of lipase activity GO:0060193 90 54 2,000 5,926E-03 0,04368259 ! positive regulation of DNA replication GO:0045740 29 18 1,000 6,546E-03 0,04810518 ! positive regulation of translation GO:0045727 28 18 1,000 6,546E-03 0,04795198 ! positive regulation of angiogenesis GO:0045766 35 18 1,000 6,546E-03 0,04779975 ! somitogenesis GO:0001756 24 18 1,000 6,546E-03 0,04764848 ! cellular response to nutrient levels GO:0031669 27 18 1,000 6,546E-03 0,04749817 ! negative regulation of neuron differentiation GO:0045665 24 18 1,000 6,546E-03 0,04734881 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 1,000 6,546E-03 0,04720038 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 6,546E-03 0,04705288 ! negative regulation of response to stimulus GO:0048585 80 56 2,000 6,558E-03 0,04698532 ! steroid hormone receptor signaling pathway GO:0030518 96 58 2,000 7,228E-03 0,05162895 ! positive regulation of protein catabolic process GO:0045732 23 19 1,000 7,284E-03 0,05186953 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 1,000 7,284E-03 0,05170944 ! cell structure disassembly during apoptosis GO:0006921 24 19 1,000 7,284E-03 0,05155033 ! apoptotic nuclear changes GO:0030262 24 19 1,000 7,284E-03 0,0513922 ! response to starvation GO:0042594 30 19 1,000 7,284E-03 0,05123504 ! plasma membrane fusion GO:0045026 23 19 1,000 7,284E-03 0,05107884 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 7,284E-03 0,05092358 ! regulation of interleukin-2 production GO:0032663 31 19 1,000 7,284E-03 0,05076927 ! positive regulation of intracellular transport GO:0032388 29 19 1,000 7,284E-03 0,05061589 ! aromatic amino acid family metabolic process GO:0009072 24 19 1,000 7,284E-03 0,05046343 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 7,284E-03 0,05031189 ! embryonic limb morphogenesis GO:0030326 86 60 2,000 7,938E-03 0,05466147 GO:0035113|embryonic appendage morphogenesis, ! regulation of heart contraction GO:0008016 91 60 2,000 7,938E-03 0,0544983 ! hindlimb morphogenesis GO:0035137 32 20 1,000 8,058E-03 0,05515794 ! positive regulation of B cell activation GO:0050871 31 20 1,000 8,058E-03 0,05499427 ! meiosis GO:0007126 96 61 2,000 8,308E-03 0,05653052 GO:0051327|M phase of meiotic cell cycle, ! meiotic cell cycle GO:0051321 97 62 2,000 8,687E-03 0,05894005 ! myeloid leukocyte differentiation GO:0002573 33 21 1,000 8,867E-03 0,05998051 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 8,867E-03 0,05980462 ! gluconeogenesis GO:0006094 25 21 1,000 8,867E-03 0,05962975 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 1,000 8,867E-03 0,0594559 ! cell aging GO:0007569 32 21 1,000 8,867E-03 0,05928306 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 8,867E-03 0,05911123 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 1,000 8,867E-03 0,05894039 ! platelet activation GO:0030168 28 21 1,000 8,867E-03 0,05877053 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 1,000 8,867E-03 0,05860165 ! response to glucocorticoid stimulus GO:0051384 33 21 1,000 8,867E-03 0,05843374 ! nerve-nerve synaptic transmission GO:0007270 36 21 1,000 8,867E-03 0,05826678 ! regulation of transcription factor activity GO:0051090 97 63 2,000 9,077E-03 0,05947903 GO:0090046|regulation of transcription regulator activity, ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 2,000 9,077E-03 0,05931005 ! regulation of lipase activity GO:0060191 109 63 2,000 9,077E-03 0,05914203 ! cell cycle checkpoint GO:0000075 108 64 2,000 9,477E-03 0,06157296 ! appendage morphogenesis GO:0035107 93 64 2,000 9,477E-03 0,06139951 GO:0035108|limb morphogenesis, ! protein import into nucleus, translocation GO:0000060 36 22 1,000 9,71E-03 0,06273485 ! glutamate signaling pathway GO:0007215 34 22 1,000 9,71E-03 0,06255912 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 9,71E-03 0,06238437 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 9,71E-03 0,0622106 ! neural tube closure GO:0001843 33 22 1,000 9,71E-03 0,06203779 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of caspase activity GO:0043281 97 65 2,000 9,887E-03 0,0629913 ! appendage development GO:0048736 94 65 2,000 9,887E-03 0,06281729 GO:0060173|limb development, ! protein oligomerization GO:0051259 100 65 2,000 9,887E-03 0,06264424 ! axon guidance GO:0007411 99 66 2,000 0,01030711 0,06512734 ! neuron fate commitment GO:0048663 32 23 1,000 0,01058809 0,06671948 ! positive regulation of cell adhesion GO:0045785 37 23 1,000 0,01058809 0,06653718 ! cellular iron ion homeostasis GO:0006879 37 23 1,000 0,01058809 0,06635588 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 0,01058809 0,06617557 ! negative regulation of DNA replication GO:0008156 35 23 1,000 0,01058809 0,06599623 ! response to corticosteroid stimulus GO:0031960 36 23 1,000 0,01058809 0,06581786 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 0,01058809 0,06564046 ! interaction with host GO:0051701 37 23 1,000 0,01058809 0,065464 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 0,01073757 0,0662102 ! regulation of neuron differentiation GO:0045664 107 67 2,000 0,01073757 0,06603317 ! pyruvate metabolic process GO:0006090 29 24 1,000 0,01149967 0,07053131 ! insulin receptor signaling pathway GO:0008286 40 24 1,000 0,01149967 0,07034372 ! mitochondrial membrane organization GO:0007006 39 24 1,000 0,01149967 0,07015714 ! neural crest cell development GO:0014032 39 24 1,000 0,01149967 0,06997153 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 1,000 0,01149967 0,06978691 ! primary neural tube formation GO:0014020 35 24 1,000 0,01149967 0,06960326 ! regulation of alpha-beta T cell activation GO:0046634 35 24 1,000 0,01149967 0,06942058 ! base-excision repair GO:0006284 31 24 1,000 0,01149967 0,06923885 ! response to drug GO:0042493 108 69 2,000 0,0116294 0,0698371 ! male gonad development GO:0008584 33 25 1,000 0,01244451 0,07453741 ! iron ion homeostasis GO:0055072 39 25 1,000 0,01244451 0,07434381 ! regulation of chromosome organization GO:0033044 35 25 1,000 0,01244451 0,07415121 ! positive regulation of nuclear division GO:0051785 39 25 1,000 0,01244451 0,0739596 GO:0045840|positive regulation of mitosis, ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 0,01244451 0,07376899 ! phosphoinositide-mediated signaling GO:0048015 109 71 2,000 0,0125627 0,07427819 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 2,000 0,0125627 0,07408773 ! lymphocyte differentiation GO:0030098 113 71 2,000 0,0125627 0,07389825 ! regulation of peptidase activity GO:0052547 106 72 2,000 0,013045 0,07653955 ! negative regulation of organelle organization GO:0010639 115 72 2,000 0,013045 0,07634479 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 0,01342212 0,07835246 ! regulation of pH GO:0006885 36 26 1,000 0,01342212 0,0781541 ! circadian rhythm GO:0007623 42 26 1,000 0,01342212 0,07795674 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 0,01342212 0,07776037 ! tube morphogenesis GO:0035239 118 73 2,000 0,01353778 0,07823337 ! mitochondrion organization GO:0007005 104 73 2,000 0,01353778 0,0780373 ! response to ionizing radiation GO:0010212 47 27 1,000 0,01443202 0,08298409 ! negative regulation of transcription regulator activity GO:0090048 47 27 1,000 0,01443202 0,08277715 GO:0043433|negative regulation of transcription factor activity, ! regulation of ligase activity GO:0051340 114 75 2,000 0,01455487 0,08327411 ! regulation of cell morphogenesis GO:0022604 140 76 2,000 0,01507924 0,08606016 ! cell junction assembly GO:0034329 56 28 1,000 0,01547373 0,08809301 ! response to organic cyclic substance GO:0014070 47 28 1,000 0,01547373 0,08787549 ! myeloid leukocyte activation GO:0002274 39 28 1,000 0,01547373 0,08765905 ! neural tube formation GO:0001841 41 28 1,000 0,01547373 0,08744367 ! regulation of DNA binding GO:0051101 119 77 2,000 0,01561419 0,08802118 ! regulation of axonogenesis GO:0050770 51 29 1,000 0,01654678 0,09305035 ! regulation of protein import into nucleus GO:0042306 53 29 1,000 0,01654678 0,0928234 ! hexose biosynthetic process GO:0019319 35 29 1,000 0,01654678 0,09259755 ! tissue homeostasis GO:0001894 42 29 1,000 0,01654678 0,0923728 GO:0048871|multicellular organismal homeostasis, ! collagen metabolic process GO:0032963 40 30 1,000 0,01765071 0,09829691 ! spindle organization GO:0007051 37 30 1,000 0,01765071 0,09805947 ! hindbrain development GO:0030902 45 30 1,000 0,01765071 0,09782319 ! embryonic epithelial tube formation GO:0001838 44 30 1,000 0,01765071 0,09758804 ! regulation of microtubule-based process GO:0032886 58 30 1,000 0,01765071 0,09735401 ! response to heat GO:0009408 41 30 1,000 0,01765071 0,09712111 ! ossification GO:0001503 134 82 2,000 0,01844841 0,10126811 GO:0060348|bone development, ! DNA damage checkpoint GO:0000077 53 31 1,000 0,01878504 0,10287046 ! mammary gland development GO:0030879 57 31 1,000 0,01878504 0,10262612 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 1,000 0,01878504 0,10238293 ! xenobiotic metabolic process GO:0006805 44 31 1,000 0,01878504 0,10214089 ! segmentation GO:0035282 41 31 1,000 0,01878504 0,10189999 ! regulation of striated muscle tissue development GO:0016202 47 31 1,000 0,01878504 0,10166022 ! metanephros development GO:0001656 58 31 1,000 0,01878504 0,10142158 ! cell fate specification GO:0001708 37 31 1,000 0,01878504 0,10118406 ! regulation of cell adhesion GO:0030155 159 83 2,000 0,01904725 0,10235672 ! regulation of defense response GO:0031347 117 84 2,000 0,01965679 0,10538605 ! microtubule cytoskeleton organization GO:0000226 120 84 2,000 0,01965679 0,10514097 ! regulation of muscle development GO:0048634 48 32 1,000 0,01994933 0,10645814 ! mitotic sister chromatid segregation GO:0000070 45 32 1,000 0,01994933 0,10621171 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 0,01994933 0,10596641 ! meiosis I GO:0007127 52 32 1,000 0,01994933 0,10572225 ! regulation of synaptic plasticity GO:0048167 52 32 1,000 0,01994933 0,10547921 ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 0,01994933 0,10523729 ! peripheral nervous system development GO:0007422 53 32 1,000 0,01994933 0,10499647 ! regulation of protein stability GO:0031647 48 32 1,000 0,01994933 0,10475675 ! calcium-mediated signaling GO:0019722 50 32 1,000 0,01994933 0,10451813 ! monosaccharide biosynthetic process GO:0046364 38 32 1,000 0,01994933 0,10428058 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 0,01994933 0,10404412 ! regulation of DNA metabolic process GO:0051052 135 85 2,000 0,02027703 0,10551397 ! Golgi vesicle transport GO:0048193 138 85 2,000 0,02027703 0,10527579 ! anterior/posterior pattern formation GO:0009952 124 85 2,000 0,02027703 0,10503868 ! regulation of membrane potential GO:0042391 128 85 2,000 0,02027703 0,10480264 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 0,02114312 0,10903401 ! negative regulation of cell adhesion GO:0007162 67 33 1,000 0,02114312 0,10879009 ! sister chromatid segregation GO:0000819 46 33 1,000 0,02114312 0,10854725 ! cell junction organization GO:0034330 63 33 1,000 0,02114312 0,1083055 ! nucleus organization GO:0006997 49 33 1,000 0,02114312 0,10806482 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 1,000 0,02114312 0,10782521 ! negative regulation of DNA binding GO:0043392 54 33 1,000 0,02114312 0,10758666 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 0,02114312 0,10734916 ! cytokinesis GO:0000910 52 33 1,000 0,02114312 0,10711271 ! skeletal muscle tissue development GO:0007519 123 87 2,000 0,02154965 0,10893231 GO:0060538|skeletal muscle organ development, ! anatomical structure homeostasis GO:0060249 136 88 2,000 0,02220204 0,11198397 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 0,02236596 0,11256389 ! regulation of neuron projection development GO:0010975 63 34 1,000 0,02236596 0,11231812 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 0,02236596 0,11207342 ! development of primary male sexual characteristics GO:0046546 44 34 1,000 0,02236596 0,11182978 ! DNA integrity checkpoint GO:0031570 57 34 1,000 0,02236596 0,1115872 ! neuron migration GO:0001764 46 34 1,000 0,02236596 0,11134567 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 1,000 0,02236596 0,11110518 ! dorsal/ventral pattern formation GO:0009953 44 34 1,000 0,02236596 0,11086573 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 0,02236596 0,11062731 ! embryonic organ development GO:0048568 45 34 1,000 0,02236596 0,11038991 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 1,000 0,02236596 0,11015353 ! reproductive developmental process GO:0003006 127 89 2,000 0,02286514 0,11237144 ! Notch signaling pathway GO:0007219 56 35 1,000 0,0236174 0,11582095 ! glycogen metabolic process GO:0005977 48 35 1,000 0,0236174 0,11557452 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 0,0236174 0,11532914 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,02489702 0,1213202 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of binding GO:0051100 58 36 1,000 0,02489702 0,12106371 ! glucan metabolic process GO:0044042 49 36 1,000 0,02489702 0,1208083 GO:0006073|cellular glucan metabolic process, ! learning GO:0007612 67 37 1,000 0,02620436 0,12688429 ! regulation of binding GO:0051098 151 95 2,000 0,02706877 0,1307945 ! alcohol biosynthetic process GO:0046165 45 38 1,000 0,02753901 0,1327877 ! mesenchymal cell development GO:0014031 64 38 1,000 0,02753901 0,1325099 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! pigmentation GO:0043473 74 38 1,000 0,02753901 0,13223326 ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 0,02890054 0,13848177 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 1,000 0,02890054 0,13819387 ! morphogenesis of embryonic epithelium GO:0016331 60 39 1,000 0,02890054 0,13790716 ! multicellular organismal metabolic process GO:0044236 50 39 1,000 0,02890054 0,13762164 ! male sex differentiation GO:0046661 53 39 1,000 0,02890054 0,1373373 ! chromatin remodeling GO:0006338 68 39 1,000 0,02890054 0,13705413 ! synapse organization GO:0050808 55 39 1,000 0,02890054 0,13677212 ! double-strand break repair GO:0006302 67 40 1,000 0,03028853 0,14304645 ! B cell differentiation GO:0030183 62 40 1,000 0,03028853 0,14275332 ! positive regulation of protein transport GO:0051222 55 40 1,000 0,03028853 0,14246139 ! energy reserve metabolic process GO:0006112 59 41 1,000 0,03170256 0,14880792 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,03170256 0,14850485 ! mitochondrial transport GO:0006839 60 42 1,000 0,03314221 0,1549331 ! cellular component disassembly GO:0022411 64 42 1,000 0,03314221 0,15461883 ! branching morphogenesis of a tube GO:0048754 72 42 1,000 0,03314221 0,15430584 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 1,000 0,03314221 0,15399411 ! regulation of cell shape GO:0008360 78 42 1,000 0,03314221 0,15368364 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,03357859 0,15539387 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,03357859 0,15508183 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,03357859 0,15477104 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,03357859 0,1544615 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,03357859 0,1541532 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,03357859 0,15384612 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,03357859 0,15354026 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,03357859 0,15323562 ! sleep GO:0030431 11 5 0,000 0,03357859 0,15293218 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,03357859 0,15262994 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,03357859 0,1523289 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,03357859 0,15202904 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! forebrain regionalization GO:0021871 6 5 0,000 0,03357859 0,15173036 ! tongue development GO:0043586 6 5 0,000 0,03357859 0,15143285 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,03357859 0,1511365 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,03357859 0,15084131 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,03357859 0,15054727 ! cobalt ion transport GO:0006824 9 5 0,000 0,03357859 0,15025438 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,03357859 0,14996262 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,03357859 0,149672 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,03357859 0,1493825 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,03357859 0,14909411 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,03357859 0,14880684 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,03357859 0,14852068 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,03357859 0,14823561 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,03357859 0,14795163 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,03357859 0,14766874 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,03357859 0,14738693 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,03357859 0,14710619 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,03357859 0,14682652 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,03357859 0,14654792 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,03357859 0,14627036 ! malate metabolic process GO:0006108 7 5 0,000 0,03357859 0,14599386 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,03357859 0,1457184 ! behavioral response to pain GO:0048266 7 5 0,000 0,03357859 0,14544398 ! clathrin coat assembly GO:0048268 11 5 0,000 0,03357859 0,14517059 ! phototransduction, visible light GO:0007603 6 5 0,000 0,03357859 0,14489822 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,03357859 0,14462687 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,03357859 0,14435654 ! mating behavior GO:0007617 6 5 0,000 0,03357859 0,14408722 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,03357859 0,1438189 ! rhythmic behavior GO:0007622 12 5 0,000 0,03357859 0,14355158 ! copulation GO:0007620 7 5 0,000 0,03357859 0,14328525 ! glial cell fate commitment GO:0021781 12 5 0,000 0,03357859 0,14301991 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,03357859 0,14275555 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,03357859 0,14249216 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,03357859 0,14222974 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,03357859 0,14196829 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,03357859 0,1417078 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,03357859 0,14144826 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,03357859 0,14118967 ! response to protozoan GO:0001562 9 5 0,000 0,03357859 0,14093203 ! lymph vessel development GO:0001945 7 5 0,000 0,03357859 0,14067532 ! endochondral ossification GO:0001958 12 5 0,000 0,03357859 0,14041955 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,03357859 0,1401647 ! parathyroid gland development GO:0060017 8 5 0,000 0,03357859 0,13991078 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,03357859 0,13965778 ! anagen GO:0042640 6 5 0,000 0,03357859 0,13940569 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,03357859 0,13915451 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,03357859 0,13890423 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,03357859 0,13865485 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,03357859 0,13840636 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,03357859 0,13815877 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,03357859 0,13791206 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,03357859 0,13766622 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,03357859 0,13742127 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,03357859 0,13717718 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,03357859 0,13693396 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,03357859 0,1366916 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,03357859 0,13645009 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,03357859 0,13620944 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,03357859 0,13596963 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,03357859 0,13573067 ! ovulation GO:0030728 6 5 0,000 0,03357859 0,13549255 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,03357859 0,13525526 GO:0033135|regulation of peptidyl-serine phosphorylation, ! valine metabolic process GO:0006573 8 5 0,000 0,03357859 0,1350188 ! response to pH GO:0009268 9 5 0,000 0,03357859 0,13478316 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,03357859 0,13454835 ! proline biosynthetic process GO:0006561 6 5 0,000 0,03357859 0,13431435 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,03357859 0,13408117 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,03357859 0,13384879 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,03357859 0,13361722 ! polyol catabolic process GO:0046174 7 5 0,000 0,03357859 0,13338644 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,03357859 0,13315647 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,03357859 0,13292728 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,03357859 0,13269889 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,03357859 0,13247127 ! nerve growth factor processing GO:0032455 7 5 0,000 0,03357859 0,13224444 ! urea metabolic process GO:0019627 6 5 0,000 0,03357859 0,13201838 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,03357859 0,13179309 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,03357859 0,13156857 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,03357859 0,13134482 ! neutrophil activation GO:0042119 5 5 0,000 0,03357859 0,13112182 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,03357859 0,13089958 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,03357859 0,13067809 ! response to food GO:0032094 5 5 0,000 0,03357859 0,13045735 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,03357859 0,13023735 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,03357859 0,1300181 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,03357859 0,12979958 ! forebrain neuron development GO:0021884 7 5 0,000 0,03357859 0,1295818 ! melanosome organization GO:0032438 7 5 0,000 0,03357859 0,12936474 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,03357859 0,12914841 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03357859 0,12893281 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,03357859 0,12871792 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,03357859 0,12850375 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,03357859 0,12829028 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,03357859 0,12807753 ! nucleoside transport GO:0015858 6 5 0,000 0,03357859 0,12786548 ! nucleoside salvage GO:0043174 7 5 0,000 0,03357859 0,12765413 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,03357859 0,12744348 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,03357859 0,12723353 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,03357859 0,12702426 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,03357859 0,12681568 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,03357859 0,12660779 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,03357859 0,12640057 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,03357859 0,12619404 ! depyrimidination GO:0045008 8 5 0,000 0,03357859 0,12598817 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,03357859 0,12578298 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,03357859 0,12557846 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,03357859 0,1253746 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,03357859 0,1251714 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,03357859 0,12496885 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,03357859 0,12476696 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,03357859 0,12456573 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,03357859 0,12436514 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,03357859 0,12416519 ! monocyte differentiation GO:0030224 8 5 0,000 0,03357859 0,12396589 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,03357859 0,12376723 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,03357859 0,1235692 ! centrosome duplication GO:0051298 5 5 0,000 0,03357859 0,12337181 ! response to UV-C GO:0010225 6 5 0,000 0,03357859 0,12317504 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,03357859 0,1229789 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,03357859 0,12278339 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,03357859 0,12258849 ! regulation of dendrite development GO:0050773 12 5 0,000 0,03357859 0,12239422 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,03357859 0,12220056 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,03357859 0,12200751 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,03357859 0,12181507 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,03357859 0,12162323 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,03357859 0,121432 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,03357859 0,12124137 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,03357859 0,12105133 ! cranial nerve morphogenesis GO:0021602 6 5 0,000 0,03357859 0,1208619 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,03357859 0,12067305 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,03357859 0,12048479 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,03357859 0,12029712 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,03357859 0,12011003 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,03357859 0,11992353 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,03357859 0,1197376 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,03357859 0,11955225 ! histone demethylation GO:0016577 9 5 0,000 0,03357859 0,11936747 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03357859 0,11918326 ! regulation of sterol transport GO:0032371 7 5 0,000 0,03357859 0,11899962 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,03357859 0,11881654 ! establishment of planar polarity GO:0001736 6 5 0,000 0,03357859 0,11863403 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,03357859 0,11845207 ! muscle cell proliferation GO:0033002 8 5 0,000 0,03357859 0,11827068 ! transcription termination GO:0006353 8 5 0,000 0,03357859 0,11808983 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,03357859 0,11790954 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,03357859 0,1177298 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,03357859 0,11755061 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,03357859 0,11737196 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,03357859 0,11719386 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,03357859 0,11701629 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,03357859 0,11683926 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,03357859 0,11666277 ! apical protein localization GO:0045176 6 5 0,000 0,03357859 0,1164868 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,03357859 0,11631137 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,03357859 0,11613647 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,03357859 0,11596209 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,03357859 0,11578823 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,03357859 0,1156149 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,03357859 0,11544208 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,03357859 0,11526978 ! glial cell migration GO:0008347 10 5 0,000 0,03357859 0,11509799 ! determination of adult lifespan GO:0008340 8 5 0,000 0,03357859 0,11492671 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,03357859 0,11475595 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03357859 0,11458568 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,03357859 0,11441593 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,03357859 0,11424667 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,03357859 0,11407792 ! neural plate development GO:0001840 6 5 0,000 0,03357859 0,11390966 ! regulation of sensory perception GO:0051931 6 5 0,000 0,03357859 0,1137419 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,03357859 0,11357463 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,03357859 0,11340786 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,03357859 0,11324157 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,03357859 0,11307577 ! sensory cilium assembly GO:0035058 6 5 0,000 0,03357859 0,11291046 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,03357859 0,11274562 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,03357859 0,11258127 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,03357859 0,1124174 ! spindle assembly GO:0051225 5 5 0,000 0,03357859 0,112254 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,03357859 0,11209108 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,03357859 0,11192862 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,03357859 0,11176664 ! organ regeneration GO:0031100 7 5 0,000 0,03357859 0,11160513 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,03357859 0,11144409 ! carnitine metabolic process GO:0009437 5 5 0,000 0,03357859 0,1112835 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,03357859 0,11112338 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,03357859 0,11096372 GO:0055081|anion homeostasis, ! positive regulation of binding GO:0051099 59 43 1,000 0,03460708 0,11419841 ! response to insulin stimulus GO:0032868 63 43 1,000 0,03460708 0,1140348 ! epithelial tube morphogenesis GO:0060562 65 43 1,000 0,03460708 0,11387166 ! regulation of cell projection organization GO:0031344 83 44 1,000 0,03609677 0,11860369 ! regulation of translational initiation GO:0006446 64 45 1,000 0,03761088 0,12340232 ! vascular process in circulatory system GO:0003018 69 45 1,000 0,03761088 0,12322653 ! cell recognition GO:0008037 58 45 1,000 0,03761088 0,12305124 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 0,03914901 0,12790159 ! cell redox homeostasis GO:0045454 63 46 1,000 0,03914901 0,12772017 ! tRNA transcription GO:0009304 11 6 0,000 0,0401589 0,13082928 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,0401589 0,13064423 GO:0045346|regulation of MHC class II biosynthetic process, ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,0401589 0,13045971 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,0401589 0,1302757 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,0401589 0,13009222 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,0401589 0,12990925 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,0401589 0,12972679 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,0401589 0,12954484 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,0401589 0,12936341 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,0401589 0,12918248 ! prostate gland development GO:0030850 9 6 0,000 0,0401589 0,12900206 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,0401589 0,12882214 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,0401589 0,12864272 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,0401589 0,1284638 GO:0021872|generation of neurons in the forebrain, ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,0401589 0,12828538 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,0401589 0,12810745 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,0401589 0,12793002 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,0401589 0,12775308 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,0401589 0,12757662 ! neuron adhesion GO:0007158 9 6 0,000 0,0401589 0,12740065 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,0401589 0,12722517 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,0401589 0,12705017 ! signal peptide processing GO:0006465 8 6 0,000 0,0401589 0,12687565 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,0401589 0,12670161 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,0401589 0,12652805 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,0401589 0,12635496 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,0401589 0,12618234 ! opsonization GO:0008228 8 6 0,000 0,0401589 0,1260102 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,0401589 0,12583852 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,0401589 0,12566731 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,0401589 0,12549657 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,0401589 0,12532629 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,0401589 0,12515647 ! photoreceptor cell development GO:0042461 10 6 0,000 0,0401589 0,12498711 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,0401589 0,12481821 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,0401589 0,12464976 ! mechanosensory behavior GO:0007638 8 6 0,000 0,0401589 0,12448177 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,0401589 0,12431423 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,0401589 0,12414714 ! response to interferon-gamma GO:0034341 12 6 0,000 0,0401589 0,1239805 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,0401589 0,12381431 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,0401589 0,12364856 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,0401589 0,12348325 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,0401589 0,12331839 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,0401589 0,12315396 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,0401589 0,12298998 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,0401589 0,12282643 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,0401589 0,12266331 ! thymic T cell selection GO:0045061 12 6 0,000 0,0401589 0,12250063 ! protein lipoylation GO:0009249 10 6 0,000 0,0401589 0,12233838 ! pigment granule organization GO:0048753 11 6 0,000 0,0401589 0,12217655 ! drug transport GO:0015893 6 6 0,000 0,0401589 0,12201516 ! cysteine metabolic process GO:0006534 7 6 0,000 0,0401589 0,12185419 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,0401589 0,12169364 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,0401589 0,12153352 ! histidine metabolic process GO:0006547 6 6 0,000 0,0401589 0,12137382 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,0401589 0,12121453 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,0401589 0,12105567 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,0401589 0,12089722 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,0401589 0,12073918 ! adenohypophysis development GO:0021984 10 6 0,000 0,0401589 0,12058156 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,0401589 0,12042435 ! hyperosmotic response GO:0006972 8 6 0,000 0,0401589 0,12026754 ! microtubule nucleation GO:0007020 10 6 0,000 0,0401589 0,12011115 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,0401589 0,11995516 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,0401589 0,11979958 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,0401589 0,1196444 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,0401589 0,11948962 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,0401589 0,11933524 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! response to dietary excess GO:0002021 7 6 0,000 0,0401589 0,11918126 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,0401589 0,11902767 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,0401589 0,11887448 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,0401589 0,11872169 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,0401589 0,11856929 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,0401589 0,11841727 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,0401589 0,11826565 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,0401589 0,11811442 ! neuron apoptosis GO:0051402 8 6 0,000 0,0401589 0,11796357 ! organic alcohol transport GO:0015850 9 6 0,000 0,0401589 0,1178131 ! T cell mediated immunity GO:0002456 12 6 0,000 0,0401589 0,11766302 ! carnitine transport GO:0015879 8 6 0,000 0,0401589 0,11751333 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,0401589 0,11736401 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,0401589 0,11721507 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0401589 0,11706651 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,0401589 0,11691832 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,0401589 0,11677051 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,0401589 0,11662307 ! parturition GO:0007567 12 6 0,000 0,0401589 0,11647601 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,0401589 0,11632931 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,0401589 0,11618299 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,0401589 0,11603703 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,0401589 0,11589143 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,0401589 0,11574621 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,0401589 0,11560134 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,0401589 0,11545684 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,0401589 0,1153127 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,0401589 0,11516892 ! macrophage differentiation GO:0030225 10 6 0,000 0,0401589 0,1150255 ! astrocyte development GO:0014002 14 6 0,000 0,0401589 0,11488243 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,0401589 0,11473972 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,0401589 0,11459736 ! interaction with symbiont GO:0051702 8 6 0,000 0,0401589 0,11445536 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,0401589 0,1143137 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,0401589 0,1141724 ! eating behavior GO:0042755 6 6 0,000 0,0401589 0,11403145 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,0401589 0,11389084 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,0401589 0,11375058 ! response to copper ion GO:0046688 9 6 0,000 0,0401589 0,11361067 ! DNA topological change GO:0006265 8 6 0,000 0,0401589 0,1134711 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,0401589 0,11333187 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,0401589 0,11319298 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,0401589 0,11305444 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0401589 0,11291623 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,0401589 0,11277836 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,0401589 0,11264082 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,0401589 0,11250362 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,0401589 0,11236676 ! hair follicle maturation GO:0048820 7 6 0,000 0,0401589 0,11223022 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,0401589 0,11209402 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,0401589 0,11195815 ! Schwann cell development GO:0014044 14 6 0,000 0,0401589 0,11182261 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,0401589 0,11168739 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,0401589 0,1115525 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,0401589 0,11141794 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,0401589 0,1112837 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,0401589 0,11114979 ! histone ubiquitination GO:0016574 7 6 0,000 0,0401589 0,11101619 ! regulation of meiosis GO:0040020 10 6 0,000 0,0401589 0,11088292 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,0401589 0,11074997 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,0401589 0,11061733 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,0401589 0,11048502 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,0401589 0,11035301 ! membrane to membrane docking GO:0022614 12 6 0,000 0,0401589 0,11022133 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,0401589 0,11008996 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,0401589 0,1099589 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,0401589 0,10982815 ! receptor internalization GO:0031623 9 6 0,000 0,0401589 0,10969771 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,0401589 0,10956758 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,0401589 0,10943776 ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,0401589 0,10930825 ! protein deubiquitination GO:0016579 8 6 0,000 0,0401589 0,10917905 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,0401589 0,10905015 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,0401589 0,10892155 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,0401589 0,10879325 ! thiamin metabolic process GO:0006772 6 6 0,000 0,0401589 0,10866526 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,0401589 0,10853757 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,0401589 0,10841018 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,0401589 0,10828309 ! progesterone metabolic process GO:0042448 8 6 0,000 0,0401589 0,10815629 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,0401589 0,10802979 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,0401589 0,10790359 GO:0046479|glycosphingolipid catabolic process, ! positive regulation of glucose import GO:0046326 6 6 0,000 0,0401589 0,10777768 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,0401589 0,10765207 ! adult feeding behavior GO:0008343 6 6 0,000 0,0401589 0,10752674 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,0401589 0,10740171 ! blastocyst growth GO:0001832 15 6 0,000 0,0401589 0,10727697 ! pigment granule transport GO:0051904 12 6 0,000 0,0401589 0,10715252 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,0401589 0,10702836 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,0401589 0,10690448 ! catecholamine transport GO:0051937 7 6 0,000 0,0401589 0,10678089 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,0401589 0,10665759 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,0401589 0,10653457 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,0401589 0,10641184 ! protein prenylation GO:0018342 10 6 0,000 0,0401589 0,10628938 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,0401589 0,10616721 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,0401589 0,10604532 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,0401589 0,10592371 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,0401589 0,10580238 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,04071076 0,10713359 ! response to temperature stimulus GO:0009266 62 48 1,000 0,04229576 0,11117744 ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 0,04229576 0,11105052 ! morphogenesis of a branching structure GO:0001763 86 49 1,000 0,04390363 0,11514064 ! germ cell development GO:0007281 68 49 1,000 0,04390363 0,1150095 ! integrin-mediated signaling pathway GO:0007229 81 49 1,000 0,04390363 0,11487866 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,04553397 0,11900923 ! membrane fusion GO:0006944 80 50 1,000 0,04553397 0,11887415 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 0,04553397 0,11873937 ! positive regulation of growth GO:0045927 67 50 1,000 0,04553397 0,1186049 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,04669478 0,12149096 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,04669478 0,12135368 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,04669478 0,12121671 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,04669478 0,12108005 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,04669478 0,1209437 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,04669478 0,12080765 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,04669478 0,12067191 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,04669478 0,12053648 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,04669478 0,12040135 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,04669478 0,12026652 ! reproductive behavior GO:0019098 12 7 0,000 0,04669478 0,120132 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,04669478 0,11999777 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,04669478 0,11986384 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,04669478 0,11973022 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,04669478 0,11959689 ! oligopeptide transport GO:0006857 11 7 0,000 0,04669478 0,11946385 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,04669478 0,11933112 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,04669478 0,11919867 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,04669478 0,11906652 ! RNA methylation GO:0001510 11 7 0,000 0,04669478 0,11893467 ! pericardium development GO:0060039 8 7 0,000 0,04669478 0,1188031 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,04669478 0,11867183 ! fibril organization GO:0043206 13 7 0,000 0,04669478 0,11854084 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,04669478 0,11841015 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,04669478 0,11827974 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,04669478 0,11814962 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,04669478 0,11801978 ! lipoprotein transport GO:0042953 9 7 0,000 0,04669478 0,11789024 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,04669478 0,11776097 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,04669478 0,11763199 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,04669478 0,11750329 ! estrogen metabolic process GO:0008210 14 7 0,000 0,04669478 0,11737487 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,04669478 0,11724673 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,04669478 0,11711887 ! chemosensory behavior GO:0007635 9 7 0,000 0,04669478 0,11699129 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,04669478 0,11686399 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,04669478 0,11673696 ! leukocyte degranulation GO:0043299 10 7 0,000 0,04669478 0,11661021 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,04669478 0,11648374 ! reflex GO:0060004 12 7 0,000 0,04669478 0,11635753 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,04669478 0,11623161 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,04669478 0,11610595 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,04669478 0,11598057 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,04669478 0,11585545 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,04669478 0,11573061 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,04669478 0,11560603 ! spinal cord patterning GO:0021511 7 7 0,000 0,04669478 0,11548173 ! adrenal gland development GO:0030325 17 7 0,000 0,04669478 0,11535768 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,04669478 0,11523391 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,04669478 0,1151104 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,04669478 0,11498716 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,04669478 0,11486418 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,04669478 0,11474146 ! endosome organization GO:0007032 10 7 0,000 0,04669478 0,114619 ! thyroid hormone generation GO:0006590 11 7 0,000 0,04669478 0,11449681 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,04669478 0,11437487 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,04669478 0,1142532 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,04669478 0,11413178 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,04669478 0,11401062 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,04669478 0,11388972 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,04669478 0,11376907 ! galactose metabolic process GO:0006012 10 7 0,000 0,04669478 0,11364868 ! vesicle fusion GO:0006906 15 7 0,000 0,04669478 0,11352855 ! intracellular pH reduction GO:0051452 10 7 0,000 0,04669478 0,11340866 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,04669478 0,11328903 ! organ growth GO:0035265 11 7 0,000 0,04669478 0,11316966 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,04669478 0,11305053 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,04669478 0,11293166 ! retinol metabolic process GO:0042572 9 7 0,000 0,04669478 0,11281303 ! behavioral fear response GO:0001662 13 7 0,000 0,04669478 0,11269465 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,04669478 0,11257652 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,04669478 0,11245864 ! rRNA modification GO:0000154 12 7 0,000 0,04669478 0,11234101 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,04669478 0,11222362 ! response to UV-B GO:0010224 11 7 0,000 0,04669478 0,11210648 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,04669478 0,11198958 ! intermediate filament organization GO:0045109 11 7 0,000 0,04669478 0,11187292 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,04669478 0,11175651 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,04669478 0,11164034 ! fibrinolysis GO:0042730 9 7 0,000 0,04669478 0,11152441 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,04669478 0,11140872 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,04669478 0,11129327 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,04669478 0,11117806 ! response to tropane GO:0014073 13 7 0,000 0,04669478 0,11106309 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,04669478 0,11094835 ! melanosome localization GO:0032400 10 7 0,000 0,04669478 0,11083385 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,04669478 0,11071959 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,04669478 0,11060557 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,04669478 0,11049177 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,04669478 0,11037822 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,04669478 0,11026489 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,04669478 0,1101518 ! mast cell activation GO:0045576 9 7 0,000 0,04669478 0,11003894 ! multicellular organismal aging GO:0010259 11 7 0,000 0,04669478 0,10992631 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,04669478 0,10981391 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,04669478 0,10970174 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,04669478 0,1095898 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,04669478 0,10947809 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,04669478 0,1093666 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,04669478 0,10925535 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,04669478 0,10914431 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,04669478 0,10903351 ! regulation of lipid transport GO:0032368 13 7 0,000 0,04669478 0,10892293 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,04669478 0,10881257 ! neuroblast proliferation GO:0007405 13 7 0,000 0,04669478 0,10870243 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,04669478 0,10859252 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,04669478 0,10848283 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,04669478 0,10837336 ! diuresis GO:0030146 12 7 0,000 0,04669478 0,10826412 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,04669478 0,10815509 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,04669478 0,10804628 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,04669478 0,10793769 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,04669478 0,10782932 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,04669478 0,10772117 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,04669478 0,10761323 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,04669478 0,10750551 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,04669478 0,107398 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,04669478 0,10729071 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,04669478 0,10718364 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,04669478 0,10707677 ! lymph node development GO:0048535 9 7 0,000 0,04669478 0,10697012 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,04669478 0,10686369 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,04669478 0,10675746 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,04669478 0,10665144 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,04669478 0,10654564 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,04669478 0,10644004 ! ATP catabolic process GO:0006200 10 7 0,000 0,04669478 0,10633466 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,04669478 0,10622948 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,04669478 0,10612451 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,04669478 0,10601975 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,04669478 0,10591519 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,04669478 0,10581084 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,04669478 0,1057067 ! muscle adaptation GO:0043500 12 7 0,000 0,04669478 0,10560276 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,04669478 0,10549902 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,04669478 0,10539549 ! retina homeostasis GO:0001895 9 7 0,000 0,04669478 0,10529216 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,04669478 0,10518903 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,04669478 0,10508611 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,04669478 0,10498339 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,04669478 0,10488086 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,04669478 0,10477854 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,04669478 0,10467642 ! muscle fiber development GO:0048747 74 51 1,000 0,04718642 0,10567552 ! regulation of protein catabolic process GO:0042176 77 51 1,000 0,04718642 0,10557272 ! positive regulation of organelle organization GO:0010638 82 51 1,000 0,04718642 0,10547012 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,0488606 0,10910619 ! establishment of organelle localization GO:0051656 85 52 1,000 0,0488606 0,10900037 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,05055615 0,11267359 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,05055615 0,11256452 ! kidney development GO:0001822 90 53 1,000 0,05055615 0,11245566 ! single fertilization GO:0007338 59 53 1,000 0,05055615 0,112347 ! cell projection assembly GO:0030031 76 53 1,000 0,05055615 0,11223856 ! amino acid transport GO:0006865 84 54 1,000 0,05227271 0,11593754 ! regulation of mitosis GO:0007088 84 54 1,000 0,05227271 0,11582585 GO:0051783|regulation of nuclear division, ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,05227271 0,11571437 ! cellular amino acid catabolic process GO:0009063 74 54 1,000 0,05227271 0,11560311 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,05318653 0,11751107 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,05318653 0,1173983 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,05318653 0,11728574 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,05318653 0,1171734 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,05318653 0,11706127 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,05318653 0,11694936 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,05318653 0,11683766 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,05318653 0,11672617 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,05318653 0,1166149 ! phosphate transport GO:0006817 10 8 0,000 0,05318653 0,11650384 ! N-glycan processing GO:0006491 12 8 0,000 0,05318653 0,11639299 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,05318653 0,11628235 ! UTP metabolic process GO:0046051 8 8 0,000 0,05318653 0,11617192 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,05318653 0,1160617 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,05318653 0,11595169 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,05318653 0,11584188 ! succinate metabolic process GO:0006105 14 8 0,000 0,05318653 0,11573229 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,05318653 0,1156229 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,05318653 0,11551372 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,05318653 0,11540474 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,05318653 0,11529597 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,05318653 0,11518741 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,05318653 0,11507905 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,05318653 0,11497089 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,05318653 0,11486294 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,05318653 0,11475519 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,05318653 0,11464764 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,05318653 0,11454029 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,05318653 0,11443314 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,05318653 0,11432619 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,05318653 0,11421945 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,05318653 0,1141129 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,05318653 0,11400655 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,05318653 0,1139004 ! astrocyte differentiation GO:0048708 16 8 0,000 0,05318653 0,11379444 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,05318653 0,11368869 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,05318653 0,11358313 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,05318653 0,11347776 ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,05318653 0,11337259 ! melanin metabolic process GO:0006582 12 8 0,000 0,05318653 0,11326762 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,05318653 0,11316284 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,05318653 0,11305825 ! macrophage activation GO:0042116 12 8 0,000 0,05318653 0,11295386 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,05318653 0,11284966 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,05318653 0,11274565 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,05318653 0,11264183 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,05318653 0,1125382 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,05318653 0,11243477 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,05318653 0,11233152 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,05318653 0,11222847 ! ruffle organization GO:0031529 11 8 0,000 0,05318653 0,1121256 ! osteoblast development GO:0002076 13 8 0,000 0,05318653 0,11202292 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,05318653 0,11192043 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,05318653 0,11181812 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,05318653 0,11171601 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,05318653 0,11161408 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,05318653 0,11151233 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,05318653 0,11141077 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,05318653 0,1113094 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,05318653 0,11120821 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,05318653 0,1111072 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,05318653 0,11100638 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,05318653 0,11090574 ! oligodendrocyte development GO:0014003 8 8 0,000 0,05318653 0,11080528 ! segment specification GO:0007379 10 8 0,000 0,05318653 0,110705 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,05318653 0,11060491 ! cellular extravasation GO:0045123 11 8 0,000 0,05318653 0,11050499 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,05318653 0,11040526 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,05318653 0,11030571 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,05318653 0,11020633 ! snRNA metabolic process GO:0016073 10 8 0,000 0,05318653 0,11010714 GO:0016180|snRNA processing, ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,05318653 0,11000812 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,05318653 0,10990928 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,05318653 0,10981062 ! nucleosome disassembly GO:0006337 12 8 0,000 0,05318653 0,10971213 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,05318653 0,10961382 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,05318653 0,10951569 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,05318653 0,10941774 ! icosanoid secretion GO:0032309 12 8 0,000 0,05318653 0,10931995 GO:0050482|arachidonic acid secretion, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,05318653 0,10922235 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,05318653 0,10912491 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,05318653 0,10902765 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,05318653 0,10893057 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,05318653 0,10883365 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,05318653 0,10873691 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,05318653 0,10864034 ! sterol catabolic process GO:0016127 9 8 0,000 0,05318653 0,10854395 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,05318653 0,10844772 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,05318653 0,10835166 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,05318653 0,10825578 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,05318653 0,10816006 ! prophase GO:0051324 11 8 0,000 0,05318653 0,10806451 ! S phase GO:0051320 8 8 0,000 0,05318653 0,10796913 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,05318653 0,10787392 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,05318653 0,10777888 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,05318653 0,107684 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,05318653 0,10758929 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,05318653 0,10749475 ! hormone catabolic process GO:0042447 13 8 0,000 0,05318653 0,10740038 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,05318653 0,10730616 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,05318653 0,10721212 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,05318653 0,10711824 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,05318653 0,10702452 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,05318653 0,10693097 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,05318653 0,10683758 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,05318653 0,10674435 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,05318653 0,10665129 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,05318653 0,10655839 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,05318653 0,10646565 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,05318653 0,10637307 ! lamellipodium assembly GO:0030032 9 8 0,000 0,05318653 0,10628065 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,05318653 0,10618839 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,05318653 0,10609629 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 0,05576741 0,11114822 ! chromosome segregation GO:0007059 83 57 1,000 0,05754485 0,11459147 ! camera-type eye development GO:0043010 88 57 1,000 0,05754485 0,11449234 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 0,05754485 0,11439339 ! gonad development GO:0008406 79 57 1,000 0,05754485 0,1142946 ! viral reproductive process GO:0022415 87 58 1,000 0,05934188 0,11776213 ! regulation of cytokine biosynthetic process GO:0042035 76 58 1,000 0,05934188 0,11766061 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,05963445 0,11813887 ! telencephalon cell migration GO:0022029 16 9 0,000 0,05963445 0,1180372 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,05963445 0,1179357 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,05963445 0,11783438 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,05963445 0,11773324 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,05963445 0,11763227 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,05963445 0,11753147 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,05963445 0,11743084 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,05963445 0,11733039 ! GTP metabolic process GO:0046039 9 9 0,000 0,05963445 0,11723011 ! elastic fiber assembly GO:0048251 13 9 0,000 0,05963445 0,11712999 ! social behavior GO:0035176 14 9 0,000 0,05963445 0,11703005 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,05963445 0,11693028 ! artery development GO:0060840 19 9 0,000 0,05963445 0,11683068 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,05963445 0,11673125 ! response to pain GO:0048265 16 9 0,000 0,05963445 0,11663199 ! protein complex disassembly GO:0043241 17 9 0,000 0,05963445 0,1165329 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,05963445 0,11643398 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,05963445 0,11633522 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,05963445 0,11623663 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,05963445 0,11613821 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,05963445 0,11603995 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,05963445 0,11594186 ! ventral spinal cord development GO:0021517 11 9 0,000 0,05963445 0,11584394 ! protein targeting to ER GO:0045047 19 9 0,000 0,05963445 0,11574618 ! T cell selection GO:0045058 18 9 0,000 0,05963445 0,11564859 ! endoderm development GO:0007492 12 9 0,000 0,05963445 0,11555116 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,05963445 0,11545389 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,05963445 0,11535679 ! arginine catabolic process GO:0006527 10 9 0,000 0,05963445 0,11525985 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,05963445 0,11516308 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,05963445 0,11506646 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,05963445 0,11497001 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,05963445 0,11487372 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,05963445 0,11477759 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,05963445 0,11468163 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,05963445 0,11458582 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,05963445 0,11449017 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,05963445 0,11439468 ! mannose metabolic process GO:0006013 9 9 0,000 0,05963445 0,11429935 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,05963445 0,11420418 ! receptor clustering GO:0043113 15 9 0,000 0,05963445 0,11410917 ! epithelial cell development GO:0002064 10 9 0,000 0,05963445 0,11401432 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,05963445 0,11391962 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,05963445 0,11382508 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,05963445 0,1137307 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,05963445 0,11363647 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,05963445 0,1135424 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,05963445 0,11344849 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,05963445 0,11335473 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,05963445 0,11326113 ! blastoderm segmentation GO:0007350 11 9 0,000 0,05963445 0,11316768 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,05963445 0,11307438 ! DNA ligation GO:0006266 14 9 0,000 0,05963445 0,11298124 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,05963445 0,11288825 ! response to amine stimulus GO:0014075 13 9 0,000 0,05963445 0,11279541 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,05963445 0,11270273 ! erythrocyte development GO:0048821 11 9 0,000 0,05963445 0,1126102 ! renal water homeostasis GO:0003091 14 9 0,000 0,05963445 0,11251782 ! postreplication repair GO:0006301 11 9 0,000 0,05963445 0,11242559 ! mRNA cleavage GO:0006379 13 9 0,000 0,05963445 0,11233352 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,05963445 0,11224159 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,05963445 0,11214982 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,05963445 0,11205819 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,05963445 0,11196671 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,05963445 0,11187539 ! acid secretion GO:0046717 14 9 0,000 0,05963445 0,11178421 ! musculoskeletal movement GO:0050881 11 9 0,000 0,05963445 0,11169318 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,05963445 0,1116023 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,05963445 0,11151156 ! purine base metabolic process GO:0006144 18 9 0,000 0,05963445 0,11142098 ! oocyte differentiation GO:0009994 12 9 0,000 0,05963445 0,11133054 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,05963445 0,11124025 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,05963445 0,1111501 ! spleen development GO:0048536 15 9 0,000 0,05963445 0,1110601 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,05963445 0,11097025 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,05963445 0,11088054 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,05963445 0,11079097 ! detection of calcium ion GO:0005513 13 9 0,000 0,05963445 0,11070155 ! blastocyst formation GO:0001825 12 9 0,000 0,05963445 0,11061228 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,05963445 0,11052315 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,05963445 0,11043416 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,05963445 0,11034531 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,05963445 0,11025661 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,05963445 0,11016805 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,05963445 0,11007963 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,05963445 0,10999136 ! prepulse inhibition GO:0060134 14 9 0,000 0,05963445 0,10990322 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,05963445 0,10981523 ! insulin secretion GO:0030073 17 9 0,000 0,05963445 0,10972738 ! sequestering of metal ion GO:0051238 11 9 0,000 0,05963445 0,10963967 ! response to nicotine GO:0035094 16 9 0,000 0,05963445 0,1095521 ! establishment of cell polarity GO:0030010 12 9 0,000 0,05963445 0,10946466 ! nucleus localization GO:0051647 15 9 0,000 0,05963445 0,10937737 ! regulation of synapse organization GO:0050807 12 9 0,000 0,05963445 0,10929022 ! activation of MAPK activity GO:0000187 84 59 1,000 0,06115815 0,11199343 ! myeloid cell differentiation GO:0030099 85 59 1,000 0,06115815 0,11190434 ! fertilization GO:0009566 68 60 1,000 0,06299334 0,11517065 ! cell-matrix adhesion GO:0007160 114 61 1,000 0,06484709 0,1184657 ! urogenital system development GO:0001655 101 61 1,000 0,06484709 0,11837168 ! negative regulation of ligase activity GO:0051352 91 61 1,000 0,06484709 0,11827781 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 1,000 0,06484709 0,11818408 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,06603881 0,1202607 ! neuron fate specification GO:0048665 11 10 0,000 0,06603881 0,12016556 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,06603881 0,12007057 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,06603881 0,11997572 ! thyroid gland development GO:0030878 19 10 0,000 0,06603881 0,11988103 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,06603881 0,11978649 ! synapsis GO:0007129 13 10 0,000 0,06603881 0,11969209 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,06603881 0,11959785 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,06603881 0,11950375 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,06603881 0,1194098 ! sulfate transport GO:0008272 12 10 0,000 0,06603881 0,119316 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,06603881 0,11922235 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,06603881 0,11912884 ! androgen metabolic process GO:0008209 13 10 0,000 0,06603881 0,11903548 ! phospholipid efflux GO:0033700 16 10 0,000 0,06603881 0,11894226 ! hippocampus development GO:0021766 19 10 0,000 0,06603881 0,11884919 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 0,000 0,06603881 0,11875627 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,06603881 0,11866349 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,06603881 0,11857086 ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,06603881 0,11847837 ! pathogenesis GO:0009405 13 10 0,000 0,06603881 0,11838602 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,06603881 0,11829382 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,06603881 0,11820176 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,06603881 0,11810985 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,06603881 0,11801808 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,06603881 0,11792645 ! melanocyte differentiation GO:0030318 15 10 0,000 0,06603881 0,11783496 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,06603881 0,11774362 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,06603881 0,11765241 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,06603881 0,11756135 ! B cell proliferation GO:0042100 14 10 0,000 0,06603881 0,11747043 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,06603881 0,11737965 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,06603881 0,11728901 ! forebrain cell migration GO:0021885 17 10 0,000 0,06603881 0,11719851 ! lipid digestion GO:0044241 15 10 0,000 0,06603881 0,11710815 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,06603881 0,11701793 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,06603881 0,11692784 ! UV protection GO:0009650 14 10 0,000 0,06603881 0,1168379 ! entry into host cell GO:0030260 20 10 0,000 0,06603881 0,11674809 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,06603881 0,11665842 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,06603881 0,11656889 ! negative regulation of ossification GO:0030279 19 10 0,000 0,06603881 0,1164795 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,06603881 0,11639024 ! regulation of organ growth GO:0046620 11 10 0,000 0,06603881 0,11630112 ! response to dsRNA GO:0043331 18 10 0,000 0,06603881 0,11621214 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,06603881 0,11612329 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,06603881 0,11603458 ! embryonic axis specification GO:0000578 12 10 0,000 0,06603881 0,11594601 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,06603881 0,11585756 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,06603881 0,11576926 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,06603881 0,11568109 ! cranial nerve development GO:0021545 12 10 0,000 0,06603881 0,11559305 ! fucose catabolic process GO:0019317 16 10 0,000 0,06603881 0,11550515 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,06603881 0,11541738 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,06603881 0,11532974 ! protein sumoylation GO:0016925 12 10 0,000 0,06603881 0,11524224 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,06603881 0,11515487 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,06603881 0,11506763 ! zymogen activation GO:0031638 14 10 0,000 0,06603881 0,11498052 ! salivary gland development GO:0007431 22 10 0,000 0,06603881 0,11489355 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,06603881 0,1148067 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,06603881 0,11471999 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,06603881 0,11463341 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,06603881 0,11454696 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,06603881 0,11446064 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,06603881 0,11437445 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,06603881 0,11428839 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,06603881 0,11420246 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,06603881 0,11411665 ! detection of bacterium GO:0016045 10 10 0,000 0,06603881 0,11403098 ! embryonic gut development GO:0048566 11 10 0,000 0,06603881 0,11394544 ! activation of innate immune response GO:0002218 10 10 0,000 0,06603881 0,11386002 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,06603881 0,11377473 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,06603881 0,11368957 ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,06603881 0,11360454 ! cytoplasmic sequestering of protein GO:0051220 14 10 0,000 0,06603881 0,11351963 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,06603881 0,11343485 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,06603881 0,1133502 ! amine catabolic process GO:0009310 90 62 1,000 0,06671909 0,11443244 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 1,000 0,06671909 0,11434717 ! organelle localization GO:0051640 96 62 1,000 0,06671909 0,11426203 ! viral reproduction GO:0016032 92 63 1,000 0,06860899 0,11741122 ! adaptive immune response GO:0002250 94 64 1,000 0,07051648 0,1205858 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! rRNA transcription GO:0009303 17 11 0,000 0,07239993 0,12371458 ! respiratory burst GO:0045730 14 11 0,000 0,07239993 0,12362274 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,07239993 0,12353103 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,07239993 0,12343946 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,07239993 0,12334802 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,07239993 0,12325672 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,07239993 0,12316555 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,07239993 0,12307452 ! RNA polyadenylation GO:0043631 19 11 0,000 0,07239993 0,12298363 ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,07239993 0,12289286 ! mating GO:0007618 14 11 0,000 0,07239993 0,12280223 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,07239993 0,12271174 ! T cell proliferation GO:0042098 20 11 0,000 0,07239993 0,12262138 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,07239993 0,12253115 ! bone resorption GO:0045453 16 11 0,000 0,07239993 0,12244105 ! regulated secretory pathway GO:0045055 14 11 0,000 0,07239993 0,12235109 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,07239993 0,12226126 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,07239993 0,12217155 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,07239993 0,12208199 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,07239993 0,12199255 ! syncytium formation GO:0006949 15 11 0,000 0,07239993 0,12190324 ! plasma membrane organization GO:0007009 18 11 0,000 0,07239993 0,12181407 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,07239993 0,12172502 ! focal adhesion formation GO:0048041 24 11 0,000 0,07239993 0,12163611 ! mitotic spindle organization GO:0007052 15 11 0,000 0,07239993 0,12154732 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,07239993 0,12145866 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,07239993 0,12137014 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,07239993 0,12128174 ! adult heart development GO:0007512 11 11 0,000 0,07239993 0,12119347 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,07239993 0,12110533 ! temperature homeostasis GO:0001659 16 11 0,000 0,07239993 0,12101732 ! L-glutamate transport GO:0015813 16 11 0,000 0,07239993 0,12092943 GO:0015800|acidic amino acid transport, ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,07239993 0,12084168 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,07239993 0,12075405 ! stem cell development GO:0048864 29 11 0,000 0,07239993 0,12066654 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,07239993 0,12057917 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,07239993 0,12049192 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,07239993 0,12040479 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,07239993 0,1203178 ! vasoconstriction GO:0042310 15 11 0,000 0,07239993 0,12023092 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,07239993 0,12014418 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,07239993 0,12005756 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,07239993 0,11997106 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,07239993 0,11988469 ! ribosome assembly GO:0042255 13 11 0,000 0,07239993 0,11979844 ! chromatin silencing GO:0006342 19 11 0,000 0,07239993 0,11971231 ! nucleosome positioning GO:0016584 13 11 0,000 0,07239993 0,11962631 ! T cell homeostasis GO:0043029 20 11 0,000 0,07239993 0,11954044 ! regulation of isotype switching GO:0045191 19 11 0,000 0,07239993 0,11945468 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,07239993 0,11936905 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,07239993 0,11928355 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,07239993 0,11919816 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,07239993 0,1191129 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,07239993 0,11902776 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,07239993 0,11894274 ! male genitalia development GO:0030539 13 11 0,000 0,07239993 0,11885784 ! cholesterol efflux GO:0033344 19 11 0,000 0,07239993 0,11877306 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,07239993 0,1186884 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,07239993 0,11860387 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,07239993 0,11851945 ! germ cell migration GO:0008354 18 11 0,000 0,07239993 0,11843516 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,07239993 0,11835098 ! defense response to fungus GO:0050832 12 11 0,000 0,07239993 0,11826692 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,07239993 0,11818299 ! lysogeny GO:0030069 18 11 0,000 0,07239993 0,11809917 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,07239993 0,11801547 ! acrosome reaction GO:0007340 13 11 0,000 0,07239993 0,11793189 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,07239993 0,11784843 ! reproductive structure development GO:0048608 90 65 1,000 0,07244123 0,11783227 ! B cell activation GO:0042113 104 65 1,000 0,07244123 0,11774899 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 1,000 0,07244123 0,11766584 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 1,000 0,07244123 0,1175828 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,07438292 0,1206493 ! regulation of Rho protein signal transduction GO:0035023 111 66 1,000 0,07438292 0,12056428 ! development of primary sexual characteristics GO:0045137 92 68 1,000 0,07831587 0,12684965 ! rhythmic process GO:0048511 105 68 1,000 0,07831587 0,12676038 ! lactation GO:0007595 20 12 0,000 0,07871808 0,12732178 ! reproductive cellular process GO:0048610 14 12 0,000 0,07871808 0,12723231 ! tRNA modification GO:0006400 14 12 0,000 0,07871808 0,12714296 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,07871808 0,12705374 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,07871808 0,12696464 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,07871808 0,12687567 ! non-recombinational repair GO:0000726 19 12 0,000 0,07871808 0,12678682 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,07871808 0,12669809 ! peroxisomal transport GO:0043574 21 12 0,000 0,07871808 0,12660949 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,07871808 0,12652102 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,07871808 0,12643266 ! palate development GO:0060021 15 12 0,000 0,07871808 0,12634444 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,07871808 0,12625633 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,07871808 0,12616835 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,07871808 0,12608048 ! arginine metabolic process GO:0006525 13 12 0,000 0,07871808 0,12599275 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,07871808 0,12590513 ! methionine metabolic process GO:0006555 13 12 0,000 0,07871808 0,12581763 ! Golgi organization GO:0007030 18 12 0,000 0,07871808 0,12573026 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,07871808 0,12564301 ! monoamine transport GO:0015844 13 12 0,000 0,07871808 0,12555588 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,07871808 0,12546887 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,07871808 0,12538198 ! L-amino acid transport GO:0015807 20 12 0,000 0,07871808 0,12529521 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,07871808 0,12520856 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,07871808 0,12512203 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,07871808 0,12503562 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,07871808 0,12494933 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,07871808 0,12486316 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,07871808 0,1247771 ! cerebellum development GO:0021549 13 12 0,000 0,07871808 0,12469117 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,07871808 0,12460535 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,07871808 0,12451965 ! histone methylation GO:0016571 15 12 0,000 0,07871808 0,12443407 ! autonomic nervous system development GO:0048483 23 12 0,000 0,07871808 0,12434861 ! gland morphogenesis GO:0022612 23 12 0,000 0,07871808 0,12426326 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,07871808 0,12417804 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,07871808 0,12409292 ! regulation of epidermis development GO:0045682 17 12 0,000 0,07871808 0,12400793 ! intestinal absorption GO:0050892 19 12 0,000 0,07871808 0,12392305 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,07871808 0,12383829 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,07871808 0,12375364 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,07871808 0,12366911 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,07871808 0,12358469 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,07871808 0,12350039 ! microspike assembly GO:0030035 23 12 0,000 0,07871808 0,12341621 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,07871808 0,12333214 ! response to cold GO:0009409 14 12 0,000 0,07871808 0,12324818 ! positive regulation of ligase activity GO:0051351 99 69 1,000 0,08030651 0,12564965 ! response to metal ion GO:0010038 103 70 1,000 0,08231286 0,12870127 ! eye development GO:0001654 111 70 1,000 0,08231286 0,12861384 ! amine transport GO:0015837 101 70 1,000 0,08231286 0,12852652 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,08499355 0,13262223 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,08499355 0,13253232 ! cGMP metabolic process GO:0046068 16 13 0,000 0,08499355 0,13244253 GO:0006182|cGMP biosynthetic process, ! water transport GO:0006833 17 13 0,000 0,08499355 0,13235286 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,08499355 0,13226331 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,08499355 0,13217388 ! lipid localization GO:0010876 24 13 0,000 0,08499355 0,13208457 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,08499355 0,13199539 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,08499355 0,13190632 ! organelle fusion GO:0048284 28 13 0,000 0,08499355 0,13181738 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,08499355 0,13172855 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,08499355 0,13163984 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,08499355 0,13155126 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,08499355 0,13146279 ! response to hexose stimulus GO:0009746 19 13 0,000 0,08499355 0,13137444 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,08499355 0,13128621 ! glutamate metabolic process GO:0006536 18 13 0,000 0,08499355 0,1311981 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,08499355 0,13111011 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,08499355 0,13102223 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,08499355 0,13093447 ! NAD metabolic process GO:0019674 21 13 0,000 0,08499355 0,13084683 ! exocrine system development GO:0035272 27 13 0,000 0,08499355 0,13075931 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,08499355 0,1306719 ! bone mineralization GO:0030282 15 13 0,000 0,08499355 0,13058461 ! regulation of exocytosis GO:0017157 17 13 0,000 0,08499355 0,13049744 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,08499355 0,13041039 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,08499355 0,13032345 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,08499355 0,13023662 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,08499355 0,13014991 ! positive regulation of protein import into nucleus GO:0042307 23 13 0,000 0,08499355 0,13006332 ! genitalia development GO:0048806 15 13 0,000 0,08499355 0,12997684 ! cellular pigmentation GO:0033059 24 13 0,000 0,08499355 0,12989048 ! tissue regeneration GO:0042246 21 13 0,000 0,08499355 0,12980423 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,08499355 0,12971809 ! cofactor transport GO:0051181 19 13 0,000 0,08499355 0,12963207 ! NADP metabolic process GO:0006739 18 13 0,000 0,08499355 0,12954617 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,08499355 0,12946038 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,08499355 0,1293747 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,08499355 0,12928913 ! gas transport GO:0015669 18 13 0,000 0,08499355 0,12920368 ! heme biosynthetic process GO:0006783 20 13 0,000 0,08499355 0,12911834 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,08499355 0,12903311 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,08499355 0,128948 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,08499355 0,128863 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,08499355 0,12877811 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,08499355 0,12869333 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,08499355 0,12860866 ! regulation of synaptic transmission GO:0050804 109 72 1,000 0,08637144 0,13060771 ! response to steroid hormone stimulus GO:0048545 114 73 1,000 0,0884231 0,13362229 ! protein import into nucleus GO:0006606 118 74 1,000 0,09048927 0,13665483 ! cellular response to hormone stimulus GO:0032870 109 74 1,000 0,09048927 0,13656516 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,09048927 0,13647561 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,09122664 0,13749755 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,09122664 0,13740751 ! superoxide anion generation GO:0042554 18 14 0,000 0,09122664 0,13731758 ! neuron maturation GO:0042551 21 14 0,000 0,09122664 0,13722777 ! regulation of S phase GO:0033261 18 14 0,000 0,09122664 0,13713808 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,09122664 0,13704851 ! myotube differentiation GO:0014902 21 14 0,000 0,09122664 0,13695905 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,09122664 0,13686971 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,09122664 0,13678049 ! inositol metabolic process GO:0006020 20 14 0,000 0,09122664 0,13669138 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,09122664 0,13660239 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,09122664 0,13651351 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,09122664 0,13642475 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,09122664 0,1363361 ! gene silencing by RNA GO:0031047 20 14 0,000 0,09122664 0,13624757 ! response to cAMP GO:0051591 19 14 0,000 0,09122664 0,13615916 ! limbic system development GO:0021761 25 14 0,000 0,09122664 0,13607086 ! startle response GO:0001964 21 14 0,000 0,09122664 0,13598267 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,09122664 0,1358946 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,09122664 0,13580664 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,09122664 0,1357188 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,09122664 0,13563107 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,09122664 0,13554345 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,09122664 0,13545595 ! glycine metabolic process GO:0006544 22 14 0,000 0,09122664 0,13536856 ! pituitary gland development GO:0021983 23 14 0,000 0,09122664 0,13528128 ! lysosomal transport GO:0007041 20 14 0,000 0,09122664 0,13519411 ! regulation of heart rate GO:0002027 23 14 0,000 0,09122664 0,13510706 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,09122664 0,13502012 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,09122664 0,13493329 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,09122664 0,13484657 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,09122664 0,13475996 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,09122664 0,13467347 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,09122664 0,13458708 ! axon cargo transport GO:0008088 27 14 0,000 0,09122664 0,13450081 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,09122664 0,13441465 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,09122664 0,13432859 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,09122664 0,13424265 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,09122664 0,13415682 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,09122664 0,1340711 ! mRNA splice site selection GO:0006376 26 14 0,000 0,09122664 0,13398548 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,09122664 0,13389998 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,09122664 0,13381458 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,09122664 0,1337293 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,09122664 0,13364412 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,09122664 0,13355905 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,09122664 0,13347409 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,09122664 0,13338923 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,09122664 0,13330449 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,09122664 0,13321985 ! cell killing GO:0001906 20 14 0,000 0,09122664 0,13313532 ! cilium assembly GO:0042384 20 14 0,000 0,09122664 0,1330509 ! peptide hormone secretion GO:0030072 23 14 0,000 0,09122664 0,13296658 ! blood coagulation GO:0007596 116 75 1,000 0,09256966 0,13483864 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 1,000 0,09256966 0,1347533 ! nuclear import GO:0051170 121 75 1,000 0,09256966 0,13466807 ! response to unfolded protein GO:0006986 99 76 1,000 0,094664 0,13762781 ! gland development GO:0048732 148 77 1,000 0,09677199 0,14060365 ! sex differentiation GO:0007548 105 77 1,000 0,09677199 0,14051488 ! protein ubiquitination GO:0016567 125 77 1,000 0,09677199 0,14042623 ! regulation of transmission of nerve impulse GO:0051969 116 77 1,000 0,09677199 0,14033769 ! carbohydrate biosynthetic process GO:0016051 97 77 1,000 0,09677199 0,14024926 ! metencephalon development GO:0022037 19 15 0,000 0,09741762 0,14109604 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,09741762 0,14100725 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,09741762 0,14091856 ! skin development GO:0043588 25 15 0,000 0,09741762 0,14082999 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,09741762 0,14074153 ! lipid phosphorylation GO:0046834 23 15 0,000 0,09741762 0,14065318 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,09741762 0,14056494 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,09741762 0,14047681 ! bile acid metabolic process GO:0008206 22 15 0,000 0,09741762 0,1403888 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,09741762 0,14030089 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,09741762 0,14021309 ! adult walking behavior GO:0007628 25 15 0,000 0,09741762 0,1401254 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,09741762 0,14003782 ! myoblast differentiation GO:0045445 27 15 0,000 0,09741762 0,13995035 ! centrosome cycle GO:0007098 16 15 0,000 0,09741762 0,13986299 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,09741762 0,13977574 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,09741762 0,1396886 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,09741762 0,13960157 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,09741762 0,13951464 ! cerebral cortex development GO:0021987 29 15 0,000 0,09741762 0,13942783 ! response to osmotic stress GO:0006970 22 15 0,000 0,09741762 0,13934112 ! vesicle coating GO:0006901 25 15 0,000 0,09741762 0,13925452 ! DNA integration GO:0015074 22 15 0,000 0,09741762 0,13916802 ! peptide secretion GO:0002790 27 15 0,000 0,09741762 0,13908164 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,09741762 0,13899536 ! regulation of vasodilation GO:0042312 24 15 0,000 0,09741762 0,13890919 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,09741762 0,13882312 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,09741762 0,13873716 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,09741762 0,13865131 ! biomineral formation GO:0031214 18 15 0,000 0,09741762 0,13856556 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,09741762 0,13847992 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,09741762 0,13839439 ! dopamine metabolic process GO:0042417 30 15 0,000 0,09741762 0,13830896 ! organic cation transport GO:0015695 19 15 0,000 0,09741762 0,13822364 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,09741762 0,13813842 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,09741762 0,13805331 ! defense response to virus GO:0051607 27 15 0,000 0,09741762 0,1379683 ! peptide hormone processing GO:0016486 19 15 0,000 0,09741762 0,1378834 ! nitrogen compound catabolic process GO:0044270 114 78 1,000 0,09889336 0,13988606 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 1,000 0,10317515 0,14585301 GO:0010498|proteasomal protein catabolic process, ! protein localization in nucleus GO:0034504 133 80 1,000 0,10317515 0,14576342 ! protein secretion GO:0009306 27 16 0,000 0,10356677 0,14622687 ! hormone secretion GO:0046879 25 16 0,000 0,10356677 0,14613716 ! bone remodeling GO:0046849 24 16 0,000 0,10356677 0,14604756 ! endothelial cell migration GO:0043542 22 16 0,000 0,10356677 0,14595807 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,10356677 0,14586869 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,10356677 0,14577942 ! glial cell development GO:0021782 24 16 0,000 0,10356677 0,14569026 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,10356677 0,14560121 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,10356677 0,14551226 ! protein polyubiquitination GO:0000209 26 16 0,000 0,10356677 0,14542343 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,10356677 0,1453347 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,10356677 0,14524608 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,10356677 0,14515757 ! fructose metabolic process GO:0006000 20 16 0,000 0,10356677 0,14506917 ! regulation of protein binding GO:0043393 27 16 0,000 0,10356677 0,14498087 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,10356677 0,14489269 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,10356677 0,14480461 ! protein export from nucleus GO:0006611 24 16 0,000 0,10356677 0,14471663 ! negative regulation of immune response GO:0050777 28 16 0,000 0,10356677 0,14462876 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,10356677 0,144541 ! DNA replication initiation GO:0006270 25 16 0,000 0,10356677 0,14445335 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,10356677 0,1443658 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,10356677 0,14427836 ! diencephalon development GO:0021536 25 16 0,000 0,10356677 0,14419103 ! oogenesis GO:0048477 23 16 0,000 0,10356677 0,1441038 ! G1 phase GO:0051318 27 16 0,000 0,10356677 0,14401667 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,10356677 0,14392965 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,10356677 0,14384274 ! steroid catabolic process GO:0006706 22 16 0,000 0,10356677 0,14375593 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,10356677 0,14366923 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,10356677 0,14358263 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,10356677 0,14349613 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,10356677 0,14340974 ! sperm-egg recognition GO:0035036 16 16 0,000 0,10356677 0,14332345 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,10356677 0,14323727 ! nerve development GO:0021675 18 16 0,000 0,10356677 0,14315119 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,10356677 0,14306521 ! negative regulation of translation GO:0017148 22 16 0,000 0,10356677 0,14297934 ! hemostasis GO:0007599 125 81 1,000 0,10533502 0,14533327 ! response to protein stimulus GO:0051789 111 81 1,000 0,10533502 0,14524614 ! regulation of neurological system process GO:0031644 122 81 1,000 0,10533502 0,14515911 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,10533502 0,14507219 GO:0002696|positive regulation of leukocyte activation, ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,10967438 0,15095816 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,10967438 0,15086787 ! negative regulation of defense response GO:0031348 19 17 0,000 0,10967438 0,15077769 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,10967438 0,15068762 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,10967438 0,15059766 ! glycerol metabolic process GO:0006071 20 17 0,000 0,10967438 0,15050781 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,10967438 0,15041806 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,10967438 0,15032842 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,10967438 0,15023888 ! signal complex assembly GO:0007172 29 17 0,000 0,10967438 0,15014945 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,10967438 0,15006013 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,10967438 0,14997092 ! memory GO:0007613 25 17 0,000 0,10967438 0,14988181 ! keratinization GO:0031424 17 17 0,000 0,10967438 0,14979281 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,10967438 0,14970391 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,10967438 0,14961511 ! retinoid metabolic process GO:0001523 22 17 0,000 0,10967438 0,14952643 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,10967438 0,14943785 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,10967438 0,14934937 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,10967438 0,149261 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,10967438 0,14917273 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,10967438 0,14908456 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,10967438 0,14899651 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,10967438 0,14890855 ! membrane budding GO:0006900 29 17 0,000 0,10967438 0,1488207 ! heme metabolic process GO:0042168 27 17 0,000 0,10967438 0,14873295 ! actin filament bundle formation GO:0051017 26 17 0,000 0,10967438 0,14864531 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,10967438 0,14855776 ! body fluid secretion GO:0007589 27 17 0,000 0,10967438 0,14847033 ! stem cell differentiation GO:0048863 36 17 0,000 0,10967438 0,14838299 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,10967438 0,14829576 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,10967438 0,14820863 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,10967438 0,1481216 ! sensory perception of pain GO:0019233 23 17 0,000 0,10967438 0,14803467 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,10967438 0,14794785 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,10967438 0,14786113 ! synaptogenesis GO:0007416 24 17 0,000 0,10967438 0,14777451 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,10967438 0,14768799 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,10967438 0,14760157 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,10967438 0,14751525 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,10967438 0,14742904 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,10967438 0,14734292 ! rRNA metabolic process GO:0016072 107 85 1,000 0,11409483 0,15319212 GO:0006364|rRNA processing, ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,11409483 0,15310275 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,11574073 0,15522081 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,11574073 0,15513035 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,11574073 0,15504 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,11574073 0,15494976 ! cAMP metabolic process GO:0046058 33 18 0,000 0,11574073 0,15485962 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,11574073 0,15476958 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,11574073 0,15467965 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,11574073 0,15458983 ! axis specification GO:0009798 26 18 0,000 0,11574073 0,15450011 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,11574073 0,15441049 GO:0050886|endocrine process, ! pancreas development GO:0031016 26 18 0,000 0,11574073 0,15432097 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,11574073 0,15423157 ! glutamine metabolic process GO:0006541 23 18 0,000 0,11574073 0,15414226 ! response to retinoic acid GO:0032526 25 18 0,000 0,11574073 0,15405306 ! pigmentation during development GO:0048066 31 18 0,000 0,11574073 0,15396396 ! central nervous system neuron development GO:0021954 30 18 0,000 0,11574073 0,15387496 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,11574073 0,15378607 ! fucose metabolic process GO:0006004 26 18 0,000 0,11574073 0,15369728 ! response to fungus GO:0009620 19 18 0,000 0,11574073 0,15360859 ! peptide cross-linking GO:0018149 31 18 0,000 0,11574073 0,15352 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,11574073 0,15343152 ! heart process GO:0003015 27 18 0,000 0,11574073 0,15334313 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,11574073 0,15325485 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,11574073 0,15316668 ! visual learning GO:0008542 35 18 0,000 0,11574073 0,1530786 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,11574073 0,15299062 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,11574073 0,15290275 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,11574073 0,15281497 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,11574073 0,1527273 ! vitamin transport GO:0051180 24 18 0,000 0,11574073 0,15263973 ! hormone transport GO:0009914 27 18 0,000 0,11574073 0,15255225 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,11574073 0,15246488 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,11574073 0,15237761 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,11574073 0,15229044 ! cell-cell recognition GO:0009988 20 18 0,000 0,11574073 0,15220336 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,11574073 0,15211639 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,11574073 0,15202952 ! gut development GO:0048565 26 18 0,000 0,11574073 0,15194274 ! carboxylic acid catabolic process GO:0046395 122 88 1,000 0,1207838 0,15847275 GO:0016054|organic acid catabolic process, ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,12176609 0,15967047 ! positive regulation of ossification GO:0045778 30 19 0,000 0,12176609 0,15957949 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,12176609 0,15948861 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,12176609 0,15939784 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,12176609 0,15930717 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,12176609 0,1592166 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,12176609 0,15912614 ! regeneration GO:0031099 32 19 0,000 0,12176609 0,15903578 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,12176609 0,15894552 ! response to alkaloid GO:0043279 32 19 0,000 0,12176609 0,15885536 ! sensory perception of taste GO:0050909 23 19 0,000 0,12176609 0,15876531 ! smooth muscle contraction GO:0006939 36 19 0,000 0,12176609 0,15867536 ! peroxisome organization GO:0007031 29 19 0,000 0,12176609 0,15858551 ! digestive system process GO:0022600 30 19 0,000 0,12176609 0,15849576 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,12176609 0,15840611 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,12176609 0,15831657 ! response to vitamin A GO:0033189 26 19 0,000 0,12176609 0,15822712 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,12176609 0,15813778 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,12176609 0,15804854 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,12176609 0,15795939 ! cytolysis GO:0019835 20 19 0,000 0,12176609 0,15787035 ! renal system process GO:0003014 35 19 0,000 0,12176609 0,15778141 ! vasodilation GO:0042311 33 19 0,000 0,12176609 0,15769257 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,12176609 0,15760383 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,12176609 0,15751519 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,12176609 0,15742665 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,12176609 0,15733821 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,12176609 0,15724986 ! sarcomere organization GO:0045214 23 19 0,000 0,12176609 0,15716162 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,12176609 0,15707347 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,12176609 0,15698543 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,12176609 0,15689748 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,12176609 0,15680963 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,12176609 0,15672188 ! protein stabilization GO:0050821 26 19 0,000 0,12176609 0,15663423 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,12529607 0,16108494 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,12775073 0,16414899 ! iron ion transport GO:0006826 37 20 0,000 0,12775073 0,16405733 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,12775073 0,16396578 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,12775073 0,16387434 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,12775073 0,16378299 ! response to vitamin GO:0033273 29 20 0,000 0,12775073 0,16369175 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,12775073 0,1636006 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,12775073 0,16350956 ! spinal cord development GO:0021510 31 20 0,000 0,12775073 0,16341862 ! response to ethanol GO:0045471 37 20 0,000 0,12775073 0,16332779 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,12775073 0,16323705 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,12775073 0,16314641 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,12775073 0,16305587 ! chromosome condensation GO:0030261 31 20 0,000 0,12775073 0,16296544 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,12775073 0,1628751 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,12775073 0,16278487 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,12775073 0,16269473 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,12775073 0,1626047 ! pallium development GO:0021543 38 20 0,000 0,12775073 0,16251476 ! DNA modification GO:0006304 28 20 0,000 0,12775073 0,16242492 ! collagen fibril organization GO:0030199 45 20 0,000 0,12775073 0,16233519 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,12775073 0,16224555 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,12775073 0,16215601 ! collagen catabolic process GO:0030574 25 20 0,000 0,12775073 0,16206657 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,12775073 0,16197722 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,12775073 0,16188798 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,12775073 0,16179884 ! alditol metabolic process GO:0019400 24 20 0,000 0,12775073 0,16170979 ! actin filament-based movement GO:0030048 34 20 0,000 0,12775073 0,16162084 ! regulation of cytoskeleton organization GO:0051493 154 93 1,000 0,13213907 0,16708074 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,13213907 0,16698894 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,13369494 0,16886236 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,13369494 0,16876968 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,13369494 0,1686771 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,13369494 0,16858462 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,13369494 0,16849225 GO:0009799|determination of symmetry, ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,13369494 0,16839997 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,13369494 0,1683078 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,13369494 0,16821573 ! vesicle docking GO:0048278 27 21 0,000 0,13369494 0,16812376 ! phototransduction GO:0007602 25 21 0,000 0,13369494 0,16803189 ! visual behavior GO:0007632 39 21 0,000 0,13369494 0,16794012 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,13369494 0,16784845 ! ovarian follicle development GO:0001541 30 21 0,000 0,13369494 0,16775687 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,13369494 0,1676654 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,13369494 0,16757403 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,13369494 0,16748276 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,13369494 0,16739159 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,13369494 0,16730052 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,13369494 0,16720954 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,13369494 0,16711867 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,13369494 0,16702789 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,13369494 0,16693722 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,13369494 0,16684664 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,13369494 0,16675616 ! fatty acid transport GO:0015908 30 21 0,000 0,13369494 0,16666577 ! immunoglobulin production GO:0002377 33 21 0,000 0,13369494 0,16657549 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,13369494 0,1664853 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,13369494 0,16639521 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,13369494 0,16630522 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,13369494 0,16621533 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,13369494 0,16612553 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,13369494 0,16603583 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,13369494 0,16594622 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,13369494 0,16585672 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,13369494 0,16576731 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,13369494 0,16567799 ! carboxylic acid transport GO:0046942 147 95 1,000 0,13674806 0,16937024 GO:0015849|organic acid transport, ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,13906596 0,17214839 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,13906596 0,17205579 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,13959897 0,17262238 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,13959897 0,17252962 ! viral genome replication GO:0019079 29 22 0,000 0,13959897 0,17243696 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,13959897 0,1723444 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,13959897 0,17225194 ! leukocyte adhesion GO:0007159 38 22 0,000 0,13959897 0,17215958 ! molting cycle process GO:0022404 40 22 0,000 0,13959897 0,17206732 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,13959897 0,17197516 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,13959897 0,1718831 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,13959897 0,17179113 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,13959897 0,17169926 GO:0051297|centrosome organization, ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,13959897 0,1716075 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,13959897 0,17151583 ! lysosome organization GO:0007040 37 22 0,000 0,13959897 0,17142425 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,13959897 0,17133278 GO:0051693|actin filament capping, ! ureteric bud development GO:0001657 32 22 0,000 0,13959897 0,1712414 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,13959897 0,17115012 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,13959897 0,17105894 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,13959897 0,17096785 ! membrane depolarization GO:0051899 35 22 0,000 0,13959897 0,17087686 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,13959897 0,17078597 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,13959897 0,17069518 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,13959897 0,17060448 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,13959897 0,17051387 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,13959897 0,17042337 ! blastocyst development GO:0001824 37 22 0,000 0,13959897 0,17033296 ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,13959897 0,17024264 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,1454631 0,17730001 ! embryonic pattern specification GO:0009880 31 23 0,000 0,1454631 0,1772061 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,1454631 0,1771123 ! regulation of transcription factor import into nucleus GO:0042990 46 23 0,000 0,1454631 0,17701859 ! vesicle targeting GO:0006903 32 23 0,000 0,1454631 0,17692497 ! osteoblast differentiation GO:0001649 40 23 0,000 0,1454631 0,17683146 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,1454631 0,17673805 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,1454631 0,17664473 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,1454631 0,17655152 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,1454631 0,1764584 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,1454631 0,17636538 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,1454631 0,17627246 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,1454631 0,17617963 ! cell fate determination GO:0001709 45 23 0,000 0,1454631 0,17608691 ! pentose metabolic process GO:0019321 31 23 0,000 0,1454631 0,17599428 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,1454631 0,17590175 ! spermatid development GO:0007286 33 23 0,000 0,1454631 0,17580931 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,1454631 0,17571698 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,1454631 0,17562474 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,1454631 0,17553259 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,1454631 0,17544055 ! telomere organization GO:0032200 32 23 0,000 0,1454631 0,1753486 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,1454631 0,17525674 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,1454631 0,17516499 ! regulation of amine transport GO:0051952 38 23 0,000 0,1454631 0,17507333 ! liver development GO:0001889 40 23 0,000 0,1454631 0,17498176 ! extracellular structure organization GO:0043062 156 99 1,000 0,14607059 0,17562067 ! protein import GO:0017038 156 99 1,000 0,14607059 0,17552892 ! regulation of body fluid levels GO:0050878 154 100 1,000 0,14842171 0,17826106 ! Ras protein signal transduction GO:0007265 162 100 1,000 0,14842171 0,17816802 ! protein localization in organelle GO:0033365 161 100 1,000 0,14842171 0,17807508 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,1512876 0,18141891 ! initiation of viral infection GO:0019059 42 24 0,000 0,1512876 0,18132437 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,1512876 0,18122993 ! superoxide metabolic process GO:0006801 32 24 0,000 0,1512876 0,18113559 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,1512876 0,18104135 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,1512876 0,1809472 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,1512876 0,18085315 ! sperm motility GO:0030317 27 24 0,000 0,1512876 0,1807592 ! vacuole organization GO:0007033 39 24 0,000 0,1512876 0,18066535 ! receptor metabolic process GO:0043112 37 24 0,000 0,1512876 0,1805716 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,1512876 0,18047794 GO:0002708|positive regulation of lymphocyte mediated immunity, ! glutathione metabolic process GO:0006749 29 24 0,000 0,1512876 0,18038438 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,1512876 0,18029092 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,1512876 0,18019755 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,1512876 0,18010428 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,15707272 0,1868946 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,15707272 0,18679797 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,15707272 0,18670143 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,15707272 0,18660499 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,15707272 0,18650865 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,15707272 0,18641242 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,15707272 0,18631628 ! peptide transport GO:0015833 43 25 0,000 0,15707272 0,18622024 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,15707272 0,1861243 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,15707272 0,18602846 ! phospholipid transport GO:0015914 35 25 0,000 0,15707272 0,18593271 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,15707272 0,18583707 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,15707272 0,18574152 ! detection of light stimulus GO:0009583 30 25 0,000 0,15707272 0,18564608 ! leukocyte proliferation GO:0070661 39 25 0,000 0,15707272 0,18555073 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,16281875 0,19223979 ! translational initiation GO:0006413 43 26 0,000 0,16281875 0,19214116 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,16281875 0,19204263 ! post-embryonic development GO:0009791 42 26 0,000 0,16281875 0,19194419 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,16281875 0,19184586 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,16281875 0,19174763 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,16281875 0,1916495 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,16281875 0,19155147 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,16281875 0,19145354 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,16281875 0,19135571 ! regulation of coagulation GO:0050818 39 26 0,000 0,16281875 0,19125798 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,16852593 0,19786097 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,16852593 0,19776002 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,16852593 0,19765917 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,16852593 0,19755843 ! membrane docking GO:0022406 39 27 0,000 0,16852593 0,19745779 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,16852593 0,19735725 ! catechol metabolic process GO:0009712 43 27 0,000 0,16852593 0,19725681 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,16852593 0,19715648 ! acute-phase response GO:0006953 42 27 0,000 0,16852593 0,19705625 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,16852593 0,19695612 ! myofibril assembly GO:0030239 36 27 0,000 0,16852593 0,19685609 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,16852593 0,19675616 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,16852593 0,19665634 ! natural killer cell activation GO:0030101 35 27 0,000 0,16852593 0,19655661 ! lipid oxidation GO:0034440 38 27 0,000 0,16852593 0,19645699 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,16852593 0,19635747 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,16852593 0,19625805 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,16852593 0,19615872 ! gene silencing GO:0016458 41 27 0,000 0,16852593 0,1960595 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,17419453 0,20255178 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,17419453 0,20244943 ! phenol metabolic process GO:0018958 44 28 0,000 0,17419453 0,20234718 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,17419453 0,20224504 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,17419453 0,202143 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,17419453 0,20204106 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,17419453 0,20193922 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,17419453 0,20183749 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,17419453 0,20173586 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,17419453 0,20163433 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,17419453 0,20153291 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,17419453 0,20143158 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,17419453 0,20133036 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,17419453 0,20122924 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,17419453 0,20112822 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,17419453 0,20102731 ! mesoderm formation GO:0001707 46 28 0,000 0,17419453 0,20092649 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,17419453 0,20082577 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,17419453 0,20072516 ! BMP signaling pathway GO:0030509 40 28 0,000 0,17419453 0,20062465 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,17419453 0,20052423 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,17982481 0,20690198 ! regulation of innate immune response GO:0045088 38 29 0,000 0,17982481 0,20679853 ! ovulation cycle process GO:0022602 41 29 0,000 0,17982481 0,20669518 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,17982481 0,20659194 ! protein targeting to membrane GO:0006612 53 29 0,000 0,17982481 0,20648879 ! mismatch repair GO:0006298 34 29 0,000 0,17982481 0,20638576 ! muscle cell development GO:0055001 38 29 0,000 0,17982481 0,20628282 ! formation of primary germ layer GO:0001704 48 29 0,000 0,17982481 0,20617999 ! telencephalon development GO:0021537 52 29 0,000 0,17982481 0,20607726 ! eye morphogenesis GO:0048592 51 29 0,000 0,17982481 0,20597463 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,17982481 0,2058721 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,18541702 0,21216873 ! organic anion transport GO:0015711 51 30 0,000 0,18541702 0,21206322 ! cholesterol transport GO:0030301 46 30 0,000 0,18541702 0,21195782 GO:0015918|sterol transport, ! embryonic skeletal system morphogenesis GO:0048704 42 30 0,000 0,18541702 0,21185253 ! spliceosome assembly GO:0000245 49 30 0,000 0,18541702 0,21174734 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,18541702 0,21164225 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,18541702 0,21153727 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,18541702 0,21143239 ! ceramide metabolic process GO:0006672 43 30 0,000 0,18541702 0,21132762 ! ovulation cycle GO:0042698 43 30 0,000 0,18541702 0,21122295 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,18541702 0,21111839 ! adult locomotory behavior GO:0008344 47 30 0,000 0,18541702 0,21101392 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,18541702 0,21090956 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,18541702 0,21080531 ! negative regulation of secretion GO:0051048 49 31 0,000 0,19097142 0,21701297 ! glial cell differentiation GO:0010001 55 31 0,000 0,19097142 0,21690581 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,19097142 0,21679875 ! odontogenesis GO:0042476 50 31 0,000 0,19097142 0,21669179 ! maintenance of protein location in cell GO:0032507 60 31 0,000 0,19097142 0,21658494 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,19097142 0,2164782 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,19097142 0,21637156 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,19097142 0,21626502 ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,19097142 0,21615859 ! RNA modification GO:0009451 40 31 0,000 0,19097142 0,21605227 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,19648826 0,22218436 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,19648826 0,22207518 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,19648826 0,22196611 GO:0006639|acylglycerol metabolic process, ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,19648826 0,22185714 ! cytokine production GO:0001816 44 32 0,000 0,19648826 0,22174828 ! vesicle localization GO:0051648 47 32 0,000 0,19648826 0,22163953 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,20196779 0,22770879 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,20196779 0,22759722 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,20196779 0,22748576 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,20196779 0,22737441 ! ear morphogenesis GO:0042471 42 33 0,000 0,20196779 0,22726317 ! actomyosin structure organization GO:0031032 43 33 0,000 0,20196779 0,22715204 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,20196779 0,22704102 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,20196779 0,22693011 ! female gonad development GO:0008585 49 33 0,000 0,20196779 0,2268193 ! positive regulation of cell development GO:0010720 54 33 0,000 0,20196779 0,2267086 ! lipid homeostasis GO:0055088 55 33 0,000 0,20196779 0,22659801 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,20196779 0,22648753 ! regulation of proteolysis GO:0030162 50 33 0,000 0,20196779 0,22637716 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,20196779 0,22626689 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,20196779 0,22615673 ! mRNA catabolic process GO:0006402 48 34 0,000 0,20741027 0,23213802 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,20741027 0,23202511 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,20741027 0,23191231 ! feeding behavior GO:0007631 45 34 0,000 0,20741027 0,23179963 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,20741027 0,23168705 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,20741027 0,23157458 ! female gamete generation GO:0007292 43 34 0,000 0,20741027 0,23146222 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,20741027 0,23134997 ! polyol metabolic process GO:0019751 44 34 0,000 0,20741027 0,23123782 ! aerobic respiration GO:0009060 47 34 0,000 0,20741027 0,23112579 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,21281595 0,23703471 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,21281595 0,23691998 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,21281595 0,23680536 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,21281595 0,23669085 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,21281595 0,23657645 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,21281595 0,23646216 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 65 35 0,000 0,21281595 0,23634798 ! Rho protein signal transduction GO:0007266 51 35 0,000 0,21281595 0,23623392 ! pigment metabolic process GO:0042440 61 35 0,000 0,21281595 0,23611996 ! protein homooligomerization GO:0051260 52 35 0,000 0,21281595 0,23600611 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,21818506 0,24184368 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,21818506 0,24172718 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,21818506 0,2416108 ! organic ether metabolic process GO:0018904 46 36 0,000 0,21818506 0,24149453 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,21818506 0,24137837 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,21818506 0,24126232 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,21818506 0,24114639 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,22351786 0,24692174 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,22351786 0,2468032 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,22351786 0,24668477 ! ion transmembrane transport GO:0034220 56 37 0,000 0,22351786 0,24656646 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,22351786 0,24644826 ! regulation of protein secretion GO:0050708 51 37 0,000 0,22351786 0,24633017 ! amino acid activation GO:0043038 52 37 0,000 0,22351786 0,2462122 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,22351786 0,24609434 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,22881458 0,25180552 ! gliogenesis GO:0042063 71 38 0,000 0,22881458 0,2516851 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,22881458 0,25156479 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,22881458 0,25144459 ! phagocytosis GO:0006909 60 38 0,000 0,22881458 0,25132452 ! maintenance of location in cell GO:0051651 69 38 0,000 0,22881458 0,25120455 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,23407548 0,25685763 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,23407548 0,25673514 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,23407548 0,25661277 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,23407548 0,25649052 ! JNK cascade GO:0007254 54 39 0,000 0,23407548 0,25636838 ! developmental growth GO:0048589 62 39 0,000 0,23407548 0,25624636 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,23930078 0,26184196 ! response to calcium ion GO:0051592 58 40 0,000 0,23930078 0,26171745 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,23930078 0,26159306 ! regulation of tube size GO:0035150 60 40 0,000 0,23930078 0,26146879 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,23930078 0,26134463 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,23930078 0,2612206 ! peptide metabolic process GO:0006518 56 40 0,000 0,23930078 0,26109668 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,23930078 0,26097288 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! epidermal cell differentiation GO:0009913 53 40 0,000 0,23930078 0,26084919 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,24449074 0,26638025 ! glucose transport GO:0015758 52 41 0,000 0,24449074 0,26625412 ! endosome transport GO:0016197 71 41 0,000 0,24449074 0,26612811 ! striated muscle contraction GO:0006941 62 41 0,000 0,24449074 0,26600222 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,24449074 0,26587645 ! biopolymer methylation GO:0043414 62 41 0,000 0,24449074 0,2657508 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,24449074 0,26562527 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,24964558 0,27109766 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,24964558 0,27096972 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,24964558 0,2708419 ! hexose transport GO:0008645 54 42 0,000 0,24964558 0,27071421 GO:0015749|monosaccharide transport, ! embryonic skeletal system development GO:0048706 56 42 0,000 0,24964558 0,27058663 ! excretion GO:0007588 63 42 0,000 0,24964558 0,27045918 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,24964558 0,27033184 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,24964558 0,27020463 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,24964558 0,27007753 ! neuromuscular process GO:0050905 79 43 0,000 0,25476555 0,27548696 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,25476555 0,2753575 ! tRNA processing GO:0008033 49 43 0,000 0,25476555 0,27522816 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,25476555 0,27509895 ! vesicle organization GO:0016050 79 43 0,000 0,25476555 0,27496985 ! methylation GO:0032259 64 43 0,000 0,25476555 0,27484088 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,25985087 0,28019549 ! glycolysis GO:0006096 53 44 0,000 0,25985087 0,28006419 ! regulation of ion transport GO:0043269 57 44 0,000 0,25985087 0,27993302 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,25985087 0,27980196 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,25985087 0,27967103 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,25985087 0,27954022 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,25985087 0,27940953 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,25985087 0,27927897 ! RNA catabolic process GO:0006401 64 45 0,000 0,26490177 0,28457454 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,26490177 0,28444168 ! cell maturation GO:0048469 60 45 0,000 0,26490177 0,28430895 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,2699185 0,28955809 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,2699185 0,2894231 ! regulation of ossification GO:0030278 71 46 0,000 0,2699185 0,28928824 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,2699185 0,2891535 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,27490128 0,29435426 ! viral infectious cycle GO:0019058 71 47 0,000 0,27490128 0,29421728 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,27490128 0,29408044 ! endocrine system development GO:0035270 83 47 0,000 0,27490128 0,29394372 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,27490128 0,29380713 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,27490128 0,29367067 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,27490128 0,29353433 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,27490128 0,29339812 ! chloride transport GO:0006821 67 48 0,000 0,27985033 0,29854164 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,27985033 0,29840323 ! gastrulation GO:0007369 73 48 0,000 0,27985033 0,29826495 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,27985033 0,2981268 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,27985033 0,29798878 ! regulation of endocytosis GO:0030100 63 48 0,000 0,27985033 0,29785089 ! nuclear export GO:0051168 69 48 0,000 0,27985033 0,29771312 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,28476589 0,30280238 ! sensory perception of smell GO:0007608 61 49 0,000 0,28476589 0,30266245 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,28476589 0,30252265 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,28476589 0,30238298 ! RNA elongation GO:0006354 62 49 0,000 0,28476589 0,30224344 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,28476589 0,30210403 ! maintenance of location GO:0051235 84 49 0,000 0,28476589 0,30196475 ! regulation of actin filament length GO:0030832 72 50 0,000 0,28964817 0,30700037 ! lipid modification GO:0030258 73 50 0,000 0,28964817 0,30685896 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,28964817 0,30671768 ! proton transport GO:0015992 75 50 0,000 0,28964817 0,30657653 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,28964817 0,30643551 ! positive regulation of secretion GO:0051047 71 51 0,000 0,29449741 0,31142255 ! hydrogen transport GO:0006818 77 51 0,000 0,29449741 0,31127943 ! adult behavior GO:0030534 80 51 0,000 0,29449741 0,31113644 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,29449741 0,31099359 ! transition metal ion transport GO:0000041 74 52 0,000 0,29931382 0,31593473 ! regulation of cellular component size GO:0032535 74 52 0,000 0,29931382 0,31578981 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,29931382 0,31564502 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,30409762 0,32054286 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,30409762 0,32039602 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,30884903 0,3252531 ! glucose catabolic process GO:0006007 66 54 0,000 0,30884903 0,32510424 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,30884903 0,32495552 ! detection of external stimulus GO:0009581 66 54 0,000 0,30884903 0,32480694 ! exocytosis GO:0006887 74 55 0,000 0,31356827 0,3296193 ! mesoderm development GO:0007498 76 55 0,000 0,31356827 0,32946872 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,31356827 0,32931828 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,31356827 0,32916797 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,31825556 0,33393604 ! carbohydrate transport GO:0008643 74 57 0,000 0,32291111 0,33866646 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,32291111 0,3385121 GO:0048609|reproductive process in a multicellular organism, ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,32291111 0,33835788 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,32291111 0,3382038 ! secondary metabolic process GO:0019748 84 57 0,000 0,32291111 0,33804987 ! developmental maturation GO:0021700 75 57 0,000 0,32291111 0,33789607 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,32753513 0,34257881 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,33212784 0,34722456 ! actin filament organization GO:0007015 95 59 0,000 0,33212784 0,3470668 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,33212784 0,34690919 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,33668944 0,35151417 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,33668944 0,35135468 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,33668944 0,35119534 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,33668944 0,35103614 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,33668944 0,35087708 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,34122015 0,35543765 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,34122015 0,35527675 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,34122015 0,35511599 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,34122015 0,35495538 ! extracellular matrix organization GO:0030198 103 61 0,000 0,34122015 0,35479491 ! neurotransmitter transport GO:0006836 81 62 0,000 0,34572016 0,35931151 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,34572016 0,35914922 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,34572016 0,35898708 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,3501897 0,36346404 ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,35462896 0,36790555 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,35462896 0,36773968 ! hexose catabolic process GO:0019320 82 64 0,000 0,35462896 0,36757395 ! defense response to bacterium GO:0042742 73 65 0,000 0,35903814 0,37197645 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,35903814 0,37180897 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,35903814 0,37164164 ! activation of immune response GO:0002253 83 65 0,000 0,35903814 0,37147446 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,36341745 0,37583639 ! antigen processing and presentation GO:0019882 96 66 0,000 0,36341745 0,37566748 ! regulation of immune effector process GO:0002697 101 66 0,000 0,36341745 0,37549871 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,36776709 0,37982232 ! acute inflammatory response GO:0002526 92 68 0,000 0,37208726 0,38411162 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,37208726 0,3839393 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,37208726 0,38376713 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,37208726 0,38359511 ! inorganic anion transport GO:0015698 93 68 0,000 0,37208726 0,38342325 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,37637815 0,38767118 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,37637815 0,38749765 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,38063997 0,39171003 ! humoral immune response GO:0006959 86 70 0,000 0,38063997 0,39153485 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,38063997 0,39135982 ! muscle cell differentiation GO:0042692 104 71 0,000 0,3848729 0,39553515 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,3848729 0,3953585 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,3848729 0,395182 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,3848729 0,39500565 ! regulation of blood pressure GO:0008217 107 73 0,000 0,3932529 0,40342626 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,3932529 0,4032464 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,39740034 0,40731764 ! digestion GO:0007586 97 74 0,000 0,39740034 0,40713621 ! response to nutrient GO:0007584 104 75 0,000 0,40151968 0,41117331 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,40151968 0,41099032 ! amine biosynthetic process GO:0009309 97 76 0,000 0,40561109 0,41499355 ! tRNA metabolic process GO:0006399 95 76 0,000 0,40561109 0,41480903 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,40967476 0,41877864 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,40967476 0,4185926 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,40967476 0,41840673 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,41371088 0,42234134 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,41771964 0,42624453 ! cellular respiration GO:0045333 107 79 0,000 0,41771964 0,42605551 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,41771964 0,42586665 ! regulation of lyase activity GO:0051339 133 79 0,000 0,41771964 0,42567797 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,41771964 0,42548945 ! chromatin assembly GO:0031497 102 80 0,000 0,42170121 0,42935493 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,42170121 0,42916495 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,42170121 0,42897514 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,42565579 0,43280651 ! mRNA transport GO:0051028 121 81 0,000 0,42565579 0,43261525 ! vitamin metabolic process GO:0006766 103 81 0,000 0,42565579 0,43242417 ! detection of stimulus GO:0051606 108 82 0,000 0,42958355 0,43622171 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,43348468 0,43998886 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,43348468 0,43979478 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,43735934 0,4435302 ! sterol metabolic process GO:0016125 120 84 0,000 0,43735934 0,44333472 ! transcription initiation GO:0006352 118 85 0,000 0,44120773 0,44703867 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,44503001 0,45071292 ! nucleosome organization GO:0034728 114 87 0,000 0,44882637 0,45435768 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,44882637 0,45415779 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,44882637 0,45395807 ! female pregnancy GO:0007565 130 87 0,000 0,44882637 0,45375853 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,45259698 0,45736953 ! establishment of RNA localization GO:0051236 128 88 0,000 0,45259698 0,45716866 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,45259698 0,45696797 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,456342 0,46054699 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,456342 0,460345 ! hormone metabolic process GO:0042445 121 90 0,000 0,46006162 0,46389378 ! RNA localization GO:0006403 135 91 0,000 0,463756 0,46741402 ! ATP metabolic process GO:0046034 137 91 0,000 0,463756 0,46720928 ! response to virus GO:0009615 122 91 0,000 0,463756 0,46700473 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,46742531 0,47049375 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,46742531 0,47028793 ! positive regulation of immune response GO:0050778 121 92 0,000 0,46742531 0,4700823 ! DNA recombination GO:0006310 146 92 0,000 0,46742531 0,46987684 ! sulfur metabolic process GO:0006790 118 92 0,000 0,46742531 0,46967157 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,47106973 0,4731268 ! electron transport chain GO:0022900 123 94 0,000 0,47468941 0,47655419 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,48185526 0,48353712 ! protein maturation GO:0051604 129 96 0,000 0,48185526 0,48332625 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,48540174 0,48667132 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,48540174 0,48645926 ! calcium ion transport GO:0006816 167 99 0,000 0,49242266 0,49328054 ! homophilic cell adhesion GO:0007156 149 100 0,000 0,49589742 0,49654509 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,49589742 0,49632901 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,49589742 0,49611312 ! divalent metal ion transport GO:0070838 171 100 0,000 0,49589742 0,49589742