pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6421-IPC-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! inner ear receptor cell differentiation GO:0060113 42 22 6,000 7,157E-12 1,748E-08 ! mechanoreceptor differentiation GO:0042490 48 24 6,000 1,441E-11 1,76E-08 ! negative regulation of phosphorylation GO:0042326 52 24 5,000 1,233E-09 1,004E-06 ! lung development GO:0030324 165 69 7,000 1,315E-09 8,029E-07 ! respiratory tube development GO:0030323 171 72 7,000 1,859E-09 9,085E-07 ! negative regulation of phosphorus metabolic process GO:0010563 56 26 5,000 2,093E-09 8,523E-07 GO:0045936|negative regulation of phosphate metabolic process, ! respiratory system development GO:0060541 175 74 7,000 2,323E-09 8,107E-07 ! positive regulation of glycolysis GO:0045821 13 5 3,000 2,342E-09 7,151E-07 ! fibroblast growth factor receptor signaling pathway GO:0008543 54 29 5,000 4,269E-09 1,159E-06 ! inner ear development GO:0048839 89 53 6,000 5,724E-09 1,398E-06 ! auditory receptor cell differentiation GO:0042491 36 17 4,000 1,275E-08 2,831E-06 ! ear development GO:0043583 114 66 6,000 2,748E-08 5,594E-06 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 3,000 3,242E-08 6,093E-06 ! intra-Golgi vesicle-mediated transport GO:0006891 48 22 4,000 5,322E-08 9,287E-06 ! positive regulation of glucose metabolic process GO:0010907 18 9 3,000 5,815E-08 9,471E-06 ! induction of positive chemotaxis GO:0050930 17 9 3,000 5,815E-08 8,879E-06 ! regulation of glycolysis GO:0006110 20 9 3,000 5,815E-08 8,357E-06 ! regulation of cellular carbohydrate catabolic process GO:0043471 21 10 3,000 9,656E-08 1,311E-05 GO:0043470|regulation of carbohydrate catabolic process, ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 3,000 9,656E-08 1,242E-05 ! positive regulation of endothelial cell proliferation GO:0001938 23 11 3,000 1,512E-07 1,847E-05 ! positive regulation of cellular catabolic process GO:0031331 34 12 3,000 2,259E-07 2,628E-05 ! regulation of positive chemotaxis GO:0050926 22 12 3,000 2,259E-07 2,509E-05 GO:0050927|positive regulation of positive chemotaxis, ! embryonic placenta development GO:0001892 21 12 3,000 2,259E-07 2,4E-05 ! positive regulation of carbohydrate metabolic process GO:0045913 23 13 3,000 3,252E-07 3,31E-05 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of catabolic process GO:0009896 72 32 4,000 3,918E-07 3,829E-05 ! negative regulation of protein amino acid phosphorylation GO:0001933 36 14 3,000 4,536E-07 4,262E-05 ! regulation of glucose metabolic process GO:0010906 28 16 3,000 8,186E-07 7,407E-05 ! negative regulation of protein kinase activity GO:0006469 144 69 5,000 9,224E-07 8,048E-05 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 131 69 5,000 9,224E-07 7,77E-05 ! negative regulation of kinase activity GO:0033673 145 70 5,000 1,005E-06 8,184E-05 ! mRNA transcription GO:0009299 10 5 2,000 1,012E-06 7,973E-05 ! regulation of generation of precursor metabolites and energy GO:0043467 37 18 3,000 1,366E-06 1,043E-04 ! negative regulation of transferase activity GO:0051348 155 74 5,000 1,398E-06 1,035E-04 ! regulation of hormone biosynthetic process GO:0046885 10 6 2,000 2,016E-06 1,449E-04 ! regulation of carbohydrate metabolic process GO:0006109 37 20 3,000 2,148E-06 1,499E-04 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of epithelial cell proliferation GO:0050678 122 45 4,000 2,263E-06 1,535E-04 ! induction of apoptosis by intracellular signals GO:0008629 95 45 4,000 2,263E-06 1,494E-04 ! positive regulation of phosphorylation GO:0042327 149 81 5,000 2,384E-06 1,532E-04 ! G1/S transition of mitotic cell cycle GO:0000082 124 46 4,000 2,529E-06 1,584E-04 ! regulation of gene-specific transcription GO:0032583 102 46 4,000 2,529E-06 1,545E-04 ! positive regulation of phosphorus metabolic process GO:0010562 156 83 5,000 2,751E-06 1,639E-04 GO:0045937|positive regulation of phosphate metabolic process, ! positive regulation of locomotion GO:0040017 44 22 3,000 3,219E-06 1,872E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! positive regulation of protein ubiquitination GO:0031398 14 7 2,000 3,516E-06 1,998E-04 ! regulation of protein export from nucleus GO:0046825 10 7 2,000 3,516E-06 1,952E-04 ! N-terminal protein amino acid acetylation GO:0006474 14 7 2,000 3,516E-06 1,909E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 16 7 2,000 3,516E-06 1,867E-04 ! regulation of chemotaxis GO:0050920 45 23 3,000 3,882E-06 2,018E-04 ! regulation of cellular catabolic process GO:0031329 55 24 3,000 4,641E-06 2,362E-04 ! histone modification GO:0016570 104 52 4,000 4,687E-06 2,337E-04 ! cartilage development GO:0051216 99 53 4,000 5,156E-06 2,519E-04 ! regulation of behavior GO:0050795 48 25 3,000 5,505E-06 2,637E-04 ! ER overload response GO:0006983 13 8 2,000 5,607E-06 2,634E-04 ! regulation of T cell differentiation in the thymus GO:0033081 14 8 2,000 5,607E-06 2,584E-04 ! positive regulation of erythrocyte differentiation GO:0045648 30 8 2,000 5,607E-06 2,537E-04 ! covalent chromatin modification GO:0016569 115 54 4,000 5,66E-06 2,514E-04 ! regulation of endothelial cell proliferation GO:0001936 60 27 3,000 7,582E-06 3,308E-04 ! positive regulation of cell migration GO:0030335 137 58 4,000 8,078E-06 3,462E-04 ! regulation of fibroblast proliferation GO:0048145 56 28 3,000 8,813E-06 3,712E-04 ! epidermal growth factor receptor signaling pathway GO:0007173 69 28 3,000 8,813E-06 3,649E-04 ! negative regulation of protein modification process GO:0031400 66 28 3,000 8,813E-06 3,588E-04 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 21 10 2,000 1,193E-05 4,778E-04 ! positive regulation vascular endothelial growth factor production GO:0010575 25 10 2,000 1,193E-05 4,701E-04 ! regulation of insulin receptor signaling pathway GO:0046626 22 10 2,000 1,193E-05 4,627E-04 ! positive regulation of cell motion GO:0051272 157 65 4,000 1,418E-05 5,413E-04 ! regulation of nitric-oxide synthase activity GO:0050999 28 11 2,000 1,635E-05 6,145E-04 ! peptide or protein amino-terminal blocking GO:0018409 22 11 2,000 1,635E-05 6,052E-04 ! chondrocyte differentiation GO:0002062 27 11 2,000 1,635E-05 5,961E-04 ! regulation of vascular endothelial growth factor production GO:0010574 26 11 2,000 1,635E-05 5,874E-04 ! negative regulation of glucose import GO:0046325 18 11 2,000 1,635E-05 5,789E-04 GO:0010829|negative regulation of glucose transport, ! positive regulation of gene-specific transcription GO:0043193 70 33 3,000 1,729E-05 6,035E-04 ! regulation of B cell proliferation GO:0030888 22 12 2,000 2,172E-05 7,475E-04 ! histone acetylation GO:0016573 27 12 2,000 2,172E-05 7,371E-04 ! regulation of hormone metabolic process GO:0032350 28 12 2,000 2,172E-05 7,27E-04 ! peptidyl-lysine modification GO:0018205 21 12 2,000 2,172E-05 7,172E-04 ! negative regulation of mast cell proliferation GO:0070667 24 12 2,000 2,172E-05 7,076E-04 GO:0042130|negative regulation of T cell proliferation, ! placenta development GO:0001890 53 35 3,000 2,197E-05 7,061E-04 ! positive regulation of protein amino acid phosphorylation GO:0001934 123 74 4,000 2,673E-05 8,48E-04 ! regulation of monooxygenase activity GO:0032768 35 13 2,000 2,814E-05 8,815E-04 ! regulation of erythrocyte differentiation GO:0045646 47 13 2,000 2,814E-05 8,703E-04 ! regulation of catabolic process GO:0009894 173 77 4,000 3,241E-05 9,898E-04 ! response to hypoxia GO:0001666 178 81 4,000 4,14E-05 1,249E-03 ! N-terminal protein amino acid modification GO:0031365 30 15 2,000 4,446E-05 1,325E-03 ! regulation of the force of heart contraction GO:0002026 31 15 2,000 4,446E-05 1,309E-03 ! histone deacetylation GO:0016575 24 15 2,000 4,446E-05 1,293E-03 ! regulation of intracellular protein transport GO:0033157 86 42 3,000 4,577E-05 1,316E-03 ! regulation of T cell differentiation GO:0045580 78 42 3,000 4,577E-05 1,3E-03 ! response to oxygen levels GO:0070482 183 83 4,000 4,656E-05 1,308E-03 ! negative regulation of transport GO:0051051 164 85 4,000 5,221E-05 1,449E-03 ! negative regulation of growth GO:0045926 168 85 4,000 5,221E-05 1,433E-03 ! regulation of protein ubiquitination GO:0031396 28 16 2,000 5,454E-05 1,48E-03 ! negative regulation of nucleocytoplasmic transport GO:0046823 35 16 2,000 5,454E-05 1,464E-03 ! negative regulation of leukocyte proliferation GO:0070664 32 16 2,000 5,454E-05 1,448E-03 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of response to external stimulus GO:0032103 88 44 3,000 5,511E-05 1,448E-03 ! regulation of nucleocytoplasmic transport GO:0046822 92 46 3,000 6,576E-05 1,709E-03 ! cell growth GO:0016049 90 46 3,000 6,576E-05 1,691E-03 ! embryonic forelimb morphogenesis GO:0035115 31 17 2,000 6,599E-05 1,679E-03 ! neutrophil chemotaxis GO:0030593 29 17 2,000 6,599E-05 1,662E-03 ! positive regulation of protein modification process GO:0031401 156 90 4,000 6,864E-05 1,711E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 39 18 2,000 7,892E-05 1,947E-03 ! regulation of lymphocyte differentiation GO:0045619 92 49 3,000 8,445E-05 2,063E-03 ! regulation of mast cell proliferation GO:0070666 89 49 3,000 8,445E-05 2,043E-03 ! negative regulation of epithelial cell proliferation GO:0050680 48 19 2,000 9,339E-05 2,237E-03 ! interphase of mitotic cell cycle GO:0051329 224 98 4,000 1,029E-04 2,441E-03 ! protein amino acid deacetylation GO:0006476 34 20 2,000 1,095E-04 2,572E-03 ! protein amino acid acetylation GO:0006473 41 20 2,000 1,095E-04 2,548E-03 ! forelimb morphogenesis GO:0035136 35 20 2,000 1,095E-04 2,524E-03 ! apoptotic mitochondrial changes GO:0008637 42 20 2,000 1,095E-04 2,5E-03 ! positive regulation of myeloid cell differentiation GO:0045639 63 20 2,000 1,095E-04 2,477E-03 ! regulation of glucose import GO:0046324 30 20 2,000 1,095E-04 2,454E-03 GO:0010827|regulation of glucose transport, ! negative regulation of T cell activation GO:0050868 41 20 2,000 1,095E-04 2,432E-03 ! regulation of leukocyte proliferation GO:0070663 97 53 3,000 1,15E-04 2,532E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of nitric oxide biosynthetic process GO:0045428 44 21 2,000 1,273E-04 2,777E-03 ! negative regulation of intracellular transport GO:0032387 44 21 2,000 1,273E-04 2,752E-03 ! positive regulation of inflammatory response GO:0050729 41 21 2,000 1,273E-04 2,728E-03 ! response to UV GO:0009411 120 55 3,000 1,33E-04 2,825E-03 ! inactivation of MAPK activity GO:0000188 45 22 2,000 1,469E-04 3,094E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 111 57 3,000 1,529E-04 3,193E-03 ! regulation of intracellular transport GO:0032386 108 57 3,000 1,529E-04 3,166E-03 ! positive regulation of epithelial cell proliferation GO:0050679 73 24 2,000 1,917E-04 3,936E-03 ! sex determination GO:0007530 48 24 2,000 1,917E-04 3,903E-03 ! regulation of oxidoreductase activity GO:0051341 48 24 2,000 1,917E-04 3,871E-03 ! regulation of homeostatic process GO:0032844 148 62 3,000 2,12E-04 4,246E-03 ! positive regulation of fibroblast proliferation GO:0048146 48 25 2,000 2,171E-04 4,313E-03 ! vasculogenesis GO:0001570 49 25 2,000 2,171E-04 4,278E-03 ! protein tetramerization GO:0051262 57 25 2,000 2,171E-04 4,244E-03 ! hemoglobin biosynthetic process GO:0042541 8 5 1,000 2,174E-04 4,215E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,174E-04 4,182E-03 ! selenocysteine incorporation GO:0001514 12 5 1,000 2,174E-04 4,149E-03 GO:0006451|translational readthrough, ! regulation of mitochondrial membrane permeability GO:0046902 15 5 1,000 2,174E-04 4,117E-03 ! metabotropic glutamate receptor signaling pathway GO:0007216 7 5 1,000 2,174E-04 4,086E-03 ! microvillus organization GO:0032528 8 5 1,000 2,174E-04 4,054E-03 GO:0030033|microvillus assembly, ! regulation of phospholipase A2 activity GO:0032429 15 5 1,000 2,174E-04 4,024E-03 ! meiotic chromosome segregation GO:0045132 10 5 1,000 2,174E-04 3,993E-03 ! response to mercury ion GO:0046689 8 5 1,000 2,174E-04 3,964E-03 ! positive regulation of chemokine production GO:0032722 8 5 1,000 2,174E-04 3,934E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 1,000 2,174E-04 3,905E-03 ! protein insertion into membrane GO:0051205 17 5 1,000 2,174E-04 3,877E-03 ! stem cell division GO:0017145 11 5 1,000 2,174E-04 3,849E-03 GO:0048103|somatic stem cell division, ! protein amino acid autophosphorylation GO:0046777 157 64 3,000 2,398E-04 4,214E-03 ! myelination GO:0042552 50 26 2,000 2,446E-04 4,268E-03 ! response to endoplasmic reticulum stress GO:0034976 46 26 2,000 2,446E-04 4,238E-03 ! negative regulation of cell development GO:0010721 83 26 2,000 2,446E-04 4,208E-03 GO:0050768|negative regulation of neurogenesis, ! cellular response to oxidative stress GO:0034599 43 27 2,000 2,742E-04 4,685E-03 ! negative regulation of lymphocyte activation GO:0051250 55 27 2,000 2,742E-04 4,652E-03 ! negative regulation of cell growth GO:0030308 142 67 3,000 2,861E-04 4,82E-03 ! protein amino acid acylation GO:0043543 59 28 2,000 3,061E-04 5,122E-03 ! dendrite development GO:0016358 67 28 2,000 3,061E-04 5,087E-03 ! negative regulation of cell size GO:0045792 144 69 3,000 3,203E-04 5,288E-03 ! embryonic hemopoiesis GO:0035162 16 6 1,000 3,251E-04 5,33E-03 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 1,000 3,251E-04 5,295E-03 ! establishment of spindle localization GO:0051293 16 6 1,000 3,251E-04 5,26E-03 GO:0051653|spindle localization, ! regulation of interleukin-13 production GO:0032656 12 6 1,000 3,251E-04 5,225E-03 ! neural tube patterning GO:0021532 8 6 1,000 3,251E-04 5,191E-03 ! oxygen homeostasis GO:0032364 10 6 1,000 3,251E-04 5,157E-03 ! myeloid dendritic cell activation GO:0001773 10 6 1,000 3,251E-04 5,124E-03 GO:0043011|myeloid dendritic cell differentiation, ! negative regulation of neuroblast proliferation GO:0007406 25 6 1,000 3,251E-04 5,091E-03 ! negative regulation of axon extension GO:0030517 24 6 1,000 3,251E-04 5,059E-03 ! maternal placenta development GO:0001893 12 6 1,000 3,251E-04 5,027E-03 ! negative regulation of B cell activation GO:0050869 14 6 1,000 3,251E-04 4,995E-03 ! ER-nuclear signaling pathway GO:0006984 52 29 2,000 3,402E-04 5,195E-03 ! regulation of B cell activation GO:0050864 55 30 2,000 3,767E-04 5,716E-03 ! cellular response to extracellular stimulus GO:0031668 52 31 2,000 4,157E-04 6,268E-03 ! ensheathment of neurons GO:0007272 64 31 2,000 4,157E-04 6,23E-03 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 60 31 2,000 4,157E-04 6,192E-03 ! regulation of helicase activity GO:0051095 16 7 1,000 4,537E-04 6,718E-03 ! mRNA stabilization GO:0048255 18 7 1,000 4,537E-04 6,677E-03 GO:0043489|RNA stabilization, ! vascular endothelial growth factor receptor signaling pathway GO:0048010 22 7 1,000 4,537E-04 6,637E-03 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 1,000 4,537E-04 6,598E-03 ! male sex determination GO:0030238 15 7 1,000 4,537E-04 6,559E-03 ! G1 DNA damage checkpoint GO:0031571 20 7 1,000 4,537E-04 6,52E-03 ! B cell lineage commitment GO:0002326 21 7 1,000 4,537E-04 6,482E-03 ! regulation of interleukin-10 production GO:0032653 13 7 1,000 4,537E-04 6,445E-03 ! positive regulation of monooxygenase activity GO:0032770 12 7 1,000 4,537E-04 6,407E-03 ! T cell lineage commitment GO:0002360 16 7 1,000 4,537E-04 6,37E-03 ! axonal fasciculation GO:0007413 19 7 1,000 4,537E-04 6,334E-03 ! learning or memory GO:0007611 161 76 3,000 4,634E-04 6,433E-03 ! leukocyte chemotaxis GO:0030595 55 33 2,000 5,011E-04 6,916E-03 GO:0060326|cell chemotaxis, ! negative regulation of protein transport GO:0051224 74 33 2,000 5,011E-04 6,877E-03 ! negative regulation of MAP kinase activity GO:0043407 78 34 2,000 5,477E-04 7,475E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 26 8 1,000 6,031E-04 8,185E-03 ! male meiosis GO:0007140 9 8 1,000 6,031E-04 8,14E-03 ! T-helper 1 type immune response GO:0042088 12 8 1,000 6,031E-04 8,096E-03 ! hemoglobin metabolic process GO:0020027 14 8 1,000 6,031E-04 8,051E-03 ! activation of caspase activity by cytochrome c GO:0008635 14 8 1,000 6,031E-04 8,008E-03 ! L-phenylalanine metabolic process GO:0006558 12 8 1,000 6,031E-04 7,964E-03 GO:0006559|L-phenylalanine catabolic process, ! positive regulation of endothelial cell migration GO:0010595 19 8 1,000 6,031E-04 7,921E-03 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 1,000 6,031E-04 7,879E-03 ! synaptic transmission, glutamatergic GO:0035249 24 8 1,000 6,031E-04 7,837E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 6,031E-04 7,796E-03 ! phosphoinositide 3-kinase cascade GO:0014065 29 8 1,000 6,031E-04 7,755E-03 ! regulation of interleukin-4 production GO:0032673 18 8 1,000 6,031E-04 7,714E-03 ! gas homeostasis GO:0033483 14 8 1,000 6,031E-04 7,674E-03 ! response to tumor cell GO:0002347 16 8 1,000 6,031E-04 7,634E-03 ! regulation of respiratory burst GO:0060263 12 8 1,000 6,031E-04 7,595E-03 ! T cell activation GO:0042110 189 84 3,000 6,77E-04 8,481E-03 ! tissue remodeling GO:0048771 78 37 2,000 7,038E-04 8,772E-03 ! androgen receptor signaling pathway GO:0030521 81 37 2,000 7,038E-04 8,728E-03 ! negative regulation of cell activation GO:0050866 69 37 2,000 7,038E-04 8,684E-03 ! regulation of protein transport GO:0051223 165 87 3,000 7,725E-04 9,483E-03 GO:0070201|regulation of establishment of protein localization, ! microtubule bundle formation GO:0001578 22 9 1,000 7,73E-04 9,443E-03 ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 1,000 7,73E-04 9,396E-03 ! fusion of sperm to egg plasma membrane GO:0007342 12 9 1,000 7,73E-04 9,349E-03 ! carbohydrate homeostasis GO:0033500 59 39 2,000 8,221E-04 9,894E-03 GO:0042593|glucose homeostasis, ! regulation of cell cycle process GO:0010564 161 90 3,000 8,772E-04 0,01050435 ! regulation of action potential in neuron GO:0019228 80 40 2,000 8,857E-04 0,01055547 ! regulation of developmental growth GO:0048638 16 10 1,000 9,633E-04 0,01142398 ! positive regulation of B cell proliferation GO:0030890 18 10 1,000 9,633E-04 0,01136879 ! regulation of long-term neuronal synaptic plasticity GO:0048169 32 10 1,000 9,633E-04 0,01131413 ! lung alveolus development GO:0048286 26 10 1,000 9,633E-04 0,01125999 ! negative regulation of striated muscle development GO:0045843 26 10 1,000 9,633E-04 0,01120638 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 25 10 1,000 9,633E-04 0,01115326 ! motor axon guidance GO:0008045 22 10 1,000 9,633E-04 0,01110066 ! regulation of bone resorption GO:0045124 25 10 1,000 9,633E-04 0,01104854 ! protein heterooligomerization GO:0051291 17 10 1,000 9,633E-04 0,01099691 ! induction of an organ GO:0001759 17 10 1,000 9,633E-04 0,01094576 ! midbrain development GO:0030901 14 10 1,000 9,633E-04 0,01089509 ! positive regulation of MAP kinase activity GO:0043406 174 93 3,000 9,914E-04 0,01116163 ! T cell differentiation GO:0030217 93 42 2,000 1,022E-03 0,01145441 ! response to xenobiotic stimulus GO:0009410 63 42 2,000 1,022E-03 0,01140211 ! epithelial cell differentiation GO:0030855 83 43 2,000 1,095E-03 0,01215967 ! regulation of T cell proliferation GO:0042129 80 43 2,000 1,095E-03 0,01210465 ! regulation of myeloid cell differentiation GO:0045637 105 43 2,000 1,095E-03 0,01205013 ! regulation of T cell activation GO:0050863 175 96 3,000 1,116E-03 0,01222371 ! regulation of protein localization GO:0032880 188 97 3,000 1,16E-03 0,01264656 ! negative regulation of muscle development GO:0048635 27 11 1,000 1,174E-03 0,01274412 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 27 11 1,000 1,174E-03 0,01268773 ! blood vessel remodeling GO:0001974 30 11 1,000 1,174E-03 0,01263184 ! negative regulation of cell-matrix adhesion GO:0001953 37 11 1,000 1,174E-03 0,01257644 GO:0010812|negative regulation of cell-substrate adhesion, ! regulation of intracellular pH GO:0051453 21 11 1,000 1,174E-03 0,01252152 ! negative regulation of axonogenesis GO:0050771 37 11 1,000 1,174E-03 0,01246708 ! nitric oxide metabolic process GO:0046209 17 11 1,000 1,174E-03 0,01241311 GO:0006809|nitric oxide biosynthetic process, ! positive regulation of leukocyte migration GO:0002687 28 11 1,000 1,174E-03 0,0123596 ! regulation of embryonic development GO:0045995 35 11 1,000 1,174E-03 0,01230656 ! leukocyte differentiation GO:0002521 232 98 3,000 1,205E-03 0,01257554 ! forebrain development GO:0030900 210 98 3,000 1,205E-03 0,01252203 ! leukocyte migration GO:0050900 75 46 2,000 1,333E-03 0,01379993 ! virus-host interaction GO:0019048 30 12 1,000 1,404E-03 0,01447383 ! tyrosine metabolic process GO:0006570 19 12 1,000 1,404E-03 0,01441302 ! regulation of leukocyte migration GO:0002685 29 12 1,000 1,404E-03 0,01435271 ! regulation of blood vessel endothelial cell migration GO:0043535 38 12 1,000 1,404E-03 0,01429291 ! developmental induction GO:0031128 22 12 1,000 1,404E-03 0,0142336 GO:0045168|cell-cell signaling involved in cell fate specification, ! localization within membrane GO:0051668 26 12 1,000 1,404E-03 0,01417479 ! neural tube development GO:0021915 91 47 2,000 1,419E-03 0,01426711 ! positive regulation of cell cycle GO:0045787 96 48 2,000 1,509E-03 0,01510392 ! positive regulation of defense response GO:0031349 88 48 2,000 1,509E-03 0,01504227 ! regulation of inflammatory response GO:0050727 84 48 2,000 1,509E-03 0,01498112 ! JAK-STAT cascade GO:0007259 82 48 2,000 1,509E-03 0,01492047 ! negative regulation of cell projection organization GO:0031345 42 13 1,000 1,654E-03 0,01629633 ! regulation of chemokine production GO:0032642 18 13 1,000 1,654E-03 0,01623088 ! cartilage condensation GO:0001502 22 13 1,000 1,654E-03 0,01616596 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 27 13 1,000 1,654E-03 0,01610155 ! response to X-ray GO:0010165 28 13 1,000 1,654E-03 0,01603765 ! aromatic amino acid family catabolic process GO:0009074 20 13 1,000 1,654E-03 0,01597426 ! regulation of mRNA stability GO:0043488 32 13 1,000 1,654E-03 0,01591137 ! regulation of action potential GO:0001508 102 50 2,000 1,698E-03 0,01626551 ! induction of apoptosis by extracellular signals GO:0008624 99 50 2,000 1,698E-03 0,01620198 ! activation of caspase activity GO:0006919 95 50 2,000 1,698E-03 0,01613893 ! positive regulation of cytokine production GO:0001819 94 50 2,000 1,698E-03 0,01607638 ! negative regulation of immune system process GO:0002683 101 51 2,000 1,798E-03 0,01695691 ! cell-cell junction assembly GO:0007043 32 14 1,000 1,924E-03 0,01807899 ! negative regulation of protein import into nucleus GO:0042308 33 14 1,000 1,924E-03 0,01800972 ! regulation of cellular pH GO:0030641 27 14 1,000 1,924E-03 0,01794098 ! response to gamma radiation GO:0010332 30 14 1,000 1,924E-03 0,01787276 ! regulation of RNA stability GO:0043487 33 14 1,000 1,924E-03 0,01780506 ! regulation of axon extension GO:0030516 43 14 1,000 1,924E-03 0,01773787 ! release of cytochrome c from mitochondria GO:0001836 31 14 1,000 1,924E-03 0,01767119 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 79 53 2,000 2,008E-03 0,01837674 ! regulation of angiogenesis GO:0045765 125 54 2,000 2,119E-03 0,01931875 ! activation of phospholipase C activity GO:0007202 110 54 2,000 2,119E-03 0,01924693 GO:0010863|positive regulation of phospholipase C activity, ! regulation of muscle contraction GO:0006937 94 54 2,000 2,119E-03 0,01917564 ! negative regulation of bone remodeling GO:0046851 34 15 1,000 2,213E-03 0,01995197 ! regulation of mRNA processing GO:0050684 26 15 1,000 2,213E-03 0,01987862 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 30 15 1,000 2,213E-03 0,0198058 ! G1/S transition checkpoint GO:0031575 37 15 1,000 2,213E-03 0,01973352 ! positive regulation of oxidoreductase activity GO:0051353 22 15 1,000 2,213E-03 0,01966176 ! synaptic transmission, cholinergic GO:0007271 24 15 1,000 2,213E-03 0,01959052 ! muscle maintenance GO:0046716 26 15 1,000 2,213E-03 0,0195198 ! epithelial to mesenchymal transition GO:0001837 30 15 1,000 2,213E-03 0,01944958 ! positive regulation of phospholipase activity GO:0010518 111 55 2,000 2,234E-03 0,01956049 ! regulation of DNA replication GO:0006275 105 56 2,000 2,352E-03 0,0205234 ! positive regulation of caspase activity GO:0043280 108 57 2,000 2,474E-03 0,02151263 GO:0010952|positive regulation of peptidase activity, ! regulation of phospholipase activity GO:0010517 113 57 2,000 2,474E-03 0,02143635 ! heart morphogenesis GO:0003007 105 57 2,000 2,474E-03 0,0213606 ! positive regulation of cell size GO:0045793 29 16 1,000 2,522E-03 0,02169147 ! regulation of interleukin-2 biosynthetic process GO:0045076 32 16 1,000 2,522E-03 0,02161536 ! neuron recognition GO:0008038 40 16 1,000 2,522E-03 0,02153978 ! negative regulation of tissue remodeling GO:0034104 37 16 1,000 2,522E-03 0,02146473 ! regulation of T-helper cell differentiation GO:0045622 30 16 1,000 2,522E-03 0,0213902 ! positive regulation of neuron apoptosis GO:0043525 32 16 1,000 2,522E-03 0,02131618 ! aging GO:0007568 112 58 2,000 2,6E-03 0,02190681 ! positive regulation of lipase activity GO:0060193 115 58 2,000 2,6E-03 0,02183153 ! negative regulation of cell cycle process GO:0010948 35 17 1,000 2,849E-03 0,02383652 ! platelet-derived growth factor receptor signaling pathway GO:0048008 31 17 1,000 2,849E-03 0,02375517 ! negative regulation of microtubule depolymerization GO:0007026 50 17 1,000 2,849E-03 0,02367437 GO:0031114|regulation of microtubule depolymerization, ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 31 17 1,000 2,849E-03 0,02359412 ! DNA fragmentation involved in apoptosis GO:0006309 27 17 1,000 2,849E-03 0,02351441 ! negative regulation of homeostatic process GO:0032845 36 17 1,000 2,849E-03 0,02343523 ! DNA catabolic process GO:0006308 94 60 2,000 2,864E-03 0,0234815 ! regulation of heart contraction GO:0008016 123 61 2,000 3,002E-03 0,02452933 ! negative regulation of response to stimulus GO:0048585 106 61 2,000 3,002E-03 0,02444756 ! patterning of blood vessels GO:0001569 43 18 1,000 3,195E-03 0,02593421 ! heart looping GO:0001947 34 18 1,000 3,195E-03 0,02584834 ! neural crest cell migration GO:0001755 41 18 1,000 3,195E-03 0,02576303 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 52 18 1,000 3,195E-03 0,02567828 ! positive regulation of translation GO:0045727 31 19 1,000 3,56E-03 0,02851715 ! regulation of neuronal synaptic plasticity GO:0048168 51 19 1,000 3,56E-03 0,02842396 ! neuromuscular junction development GO:0007528 43 19 1,000 3,56E-03 0,02833137 ! regulation of endothelial cell migration GO:0010594 45 19 1,000 3,56E-03 0,02823939 ! proximal/distal pattern formation GO:0009954 33 19 1,000 3,56E-03 0,028148 ! steroid hormone receptor signaling pathway GO:0030518 146 66 2,000 3,752E-03 0,02957118 ! embryonic limb morphogenesis GO:0030326 139 67 2,000 3,915E-03 0,03075244 GO:0035113|embryonic appendage morphogenesis, ! positive regulation of angiogenesis GO:0045766 50 20 1,000 3,944E-03 0,03087956 ! positive regulation of nucleocytoplasmic transport GO:0046824 40 20 1,000 3,944E-03 0,03078091 ! peptidyl-serine phosphorylation GO:0018105 44 20 1,000 3,944E-03 0,03068288 ! regulation of interleukin-2 production GO:0032663 39 20 1,000 3,944E-03 0,03058547 ! cell-cell junction organization GO:0045216 43 20 1,000 3,944E-03 0,03048868 ! aromatic compound catabolic process GO:0019439 31 20 1,000 3,944E-03 0,0303925 ! regulation of lipase activity GO:0060191 137 68 2,000 4,082E-03 0,03135621 ! cell structure disassembly during apoptosis GO:0006921 32 21 1,000 4,345E-03 0,03327848 ! plasma membrane fusion GO:0045026 33 21 1,000 4,345E-03 0,03317449 ! cellular monovalent inorganic cation homeostasis GO:0030004 42 21 1,000 4,345E-03 0,03307114 ! cell cycle checkpoint GO:0000075 145 71 2,000 4,607E-03 0,03495588 ! intracellular receptor-mediated signaling pathway GO:0030522 156 71 2,000 4,607E-03 0,03484766 ! positive regulation of protein catabolic process GO:0045732 44 22 1,000 4,765E-03 0,03593066 ! hindlimb morphogenesis GO:0035137 47 22 1,000 4,765E-03 0,0358201 ! glutamate signaling pathway GO:0007215 48 22 1,000 4,765E-03 0,03571022 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 56 22 1,000 4,765E-03 0,03560102 ! cellular response to starvation GO:0009267 37 22 1,000 4,765E-03 0,03549248 ! apoptotic nuclear changes GO:0030262 34 22 1,000 4,765E-03 0,0353846 ! cell aging GO:0007569 48 22 1,000 4,765E-03 0,03527737 ! regulation of alpha-beta T cell differentiation GO:0046637 41 22 1,000 4,765E-03 0,03517079 ! positive regulation of intracellular transport GO:0032388 42 22 1,000 4,765E-03 0,03506486 ! response to glucocorticoid stimulus GO:0051384 42 22 1,000 4,765E-03 0,03495956 ! peptidyl-serine modification GO:0018209 50 22 1,000 4,765E-03 0,03485489 ! positive regulation of B cell activation GO:0050871 42 22 1,000 4,765E-03 0,03475084 ! regulation of mitotic metaphase/anaphase transition GO:0030071 44 22 1,000 4,765E-03 0,03464742 ! appendage morphogenesis GO:0035107 150 72 2,000 4,791E-03 0,03473331 GO:0035108|limb morphogenesis, ! appendage development GO:0048736 151 73 2,000 4,98E-03 0,03599159 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 136 74 2,000 5,172E-03 0,03727422 ! positive regulation of DNA replication GO:0045740 44 23 1,000 5,203E-03 0,03738553 ! gluconeogenesis GO:0006094 38 23 1,000 5,203E-03 0,0372759 ! regulation of cell-matrix adhesion GO:0001952 81 23 1,000 5,203E-03 0,0371669 GO:0010810|regulation of cell-substrate adhesion, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 49 23 1,000 5,203E-03 0,03705854 ! negative regulation of Wnt receptor signaling pathway GO:0030178 44 23 1,000 5,203E-03 0,03695082 ! nerve-nerve synaptic transmission GO:0007270 59 23 1,000 5,203E-03 0,03684371 ! regulation of transcription factor activity GO:0051090 137 75 2,000 5,369E-03 0,03791216 GO:0090046|regulation of transcription regulator activity, ! phosphoinositide-mediated signaling GO:0048015 141 75 2,000 5,369E-03 0,0378029 ! axon guidance GO:0007411 162 75 2,000 5,369E-03 0,03769427 ! lymphocyte differentiation GO:0030098 193 76 2,000 5,571E-03 0,03899759 ! positive regulation of cell adhesion GO:0045785 61 24 1,000 5,659E-03 0,03949729 ! DNA catabolic process, endonucleolytic GO:0000737 38 24 1,000 5,659E-03 0,03938476 ! response to corticosteroid stimulus GO:0031960 46 24 1,000 5,659E-03 0,03927287 ! platelet activation GO:0030168 41 24 1,000 5,659E-03 0,03916162 ! aromatic amino acid family metabolic process GO:0009072 37 24 1,000 5,659E-03 0,03905099 ! regulation of microtubule polymerization or depolymerization GO:0031110 68 24 1,000 5,659E-03 0,03894099 ! regulation of endopeptidase activity GO:0052548 141 77 2,000 5,777E-03 0,03964518 ! protein import into nucleus, translocation GO:0000060 51 25 1,000 6,132E-03 0,04196083 ! myeloid leukocyte differentiation GO:0002573 46 25 1,000 6,132E-03 0,04184362 ! G2/M transition of mitotic cell cycle GO:0000086 45 25 1,000 6,132E-03 0,04172706 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 51 25 1,000 6,132E-03 0,04161115 ! negative regulation of DNA replication GO:0008156 45 25 1,000 6,132E-03 0,04149589 ! regulation of alpha-beta T cell activation GO:0046634 48 25 1,000 6,132E-03 0,04138126 ! interaction with host GO:0051701 66 25 1,000 6,132E-03 0,04126726 ! regulation of ubiquitin-protein ligase activity GO:0051438 136 79 2,000 6,203E-03 0,04163162 ! protein oligomerization GO:0051259 149 79 2,000 6,203E-03 0,04151756 ! negative regulation of organelle organization GO:0010639 181 80 2,000 6,423E-03 0,04287085 ! pyruvate metabolic process GO:0006090 43 26 1,000 6,622E-03 0,04408325 ! peptidyl-tyrosine phosphorylation GO:0018108 55 26 1,000 6,622E-03 0,04396346 ! neural crest cell development GO:0014032 59 26 1,000 6,622E-03 0,04384431 GO:0014033|neural crest cell differentiation, ! positive regulation of nuclear division GO:0051785 41 26 1,000 6,622E-03 0,04372582 GO:0045840|positive regulation of mitosis, ! neural tube closure GO:0001843 58 26 1,000 6,622E-03 0,04360796 GO:0060606|tube closure, ! meiosis GO:0007126 143 81 2,000 6,647E-03 0,04365261 GO:0051327|M phase of meiotic cell cycle, ! regulation of peptidase activity GO:0052547 150 82 2,000 6,876E-03 0,04503509 ! meiotic cell cycle GO:0051321 144 82 2,000 6,876E-03 0,04491468 ! response to drug GO:0042493 149 83 2,000 7,11E-03 0,04631663 ! tube lumen formation GO:0035148 59 27 1,000 7,13E-03 0,04632776 ! insulin receptor signaling pathway GO:0008286 66 27 1,000 7,13E-03 0,04620488 ! mitochondrial membrane organization GO:0007006 60 27 1,000 7,13E-03 0,04608264 ! response to starvation GO:0042594 47 27 1,000 7,13E-03 0,04596105 ! response to toxin GO:0009636 49 27 1,000 7,13E-03 0,0458401 ! regulation of chromosome organization GO:0033044 49 27 1,000 7,13E-03 0,04571979 ! cellular response to nutrient levels GO:0031669 45 27 1,000 7,13E-03 0,0456001 ! regulation of ligase activity GO:0051340 147 84 2,000 7,348E-03 0,04686885 ! regulation of neuron differentiation GO:0045664 187 85 2,000 7,591E-03 0,0482923 ! neuron fate commitment GO:0048663 52 28 1,000 7,655E-03 0,04857574 ! circadian rhythm GO:0007623 56 28 1,000 7,655E-03 0,0484499 ! base-excision repair GO:0006284 41 28 1,000 7,655E-03 0,0483247 ! peptidyl-tyrosine modification GO:0018212 57 28 1,000 7,655E-03 0,04820015 ! mitochondrion organization GO:0007005 159 87 2,000 8,091E-03 0,05081158 ! positive regulation of smooth muscle cell proliferation GO:0048661 46 29 1,000 8,197E-03 0,05134718 ! cellular iron ion homeostasis GO:0006879 57 29 1,000 8,197E-03 0,05121585 ! primary neural tube formation GO:0014020 61 29 1,000 8,197E-03 0,0510852 ! response to organic cyclic substance GO:0014070 58 29 1,000 8,197E-03 0,05095521 ! somitogenesis GO:0001756 52 29 1,000 8,197E-03 0,05082589 ! negative regulation of neuron differentiation GO:0045665 46 29 1,000 8,197E-03 0,05069721 ! regulation of DNA binding GO:0051101 167 89 2,000 8,61E-03 0,05311493 ! tube morphogenesis GO:0035239 194 89 2,000 8,61E-03 0,05298114 ! negative regulation of transcription regulator activity GO:0090048 57 30 1,000 8,756E-03 0,05374383 GO:0043433|negative regulation of transcription factor activity, ! tissue homeostasis GO:0001894 50 30 1,000 8,756E-03 0,05360914 GO:0048871|multicellular organismal homeostasis, ! ossification GO:0001503 205 91 2,000 9,148E-03 0,05587009 ! cell junction assembly GO:0034329 85 31 1,000 9,331E-03 0,05684586 ! male gonad development GO:0008584 56 31 1,000 9,331E-03 0,05670445 ! iron ion homeostasis GO:0055072 60 31 1,000 9,331E-03 0,05656374 ! regulation of microtubule cytoskeleton organization GO:0070507 77 31 1,000 9,331E-03 0,05642373 ! response to heat GO:0009408 54 31 1,000 9,331E-03 0,05628442 ! bone development GO:0060348 206 92 2,000 9,424E-03 0,05670672 ! regulation of cell adhesion GO:0030155 241 92 2,000 9,424E-03 0,05656739 ! regulation of cell morphogenesis GO:0022604 243 93 2,000 9,705E-03 0,05811182 ! collagen metabolic process GO:0032963 49 32 1,000 9,922E-03 0,05926754 ! spindle organization GO:0007051 50 32 1,000 9,922E-03 0,05912299 ! metanephros development GO:0001656 81 32 1,000 9,922E-03 0,05897913 ! regulation of protein import into nucleus GO:0042306 69 32 1,000 9,922E-03 0,05883598 ! hexose biosynthetic process GO:0019319 53 32 1,000 9,922E-03 0,05869352 ! peripheral nervous system development GO:0007422 68 32 1,000 9,922E-03 0,05855175 ! hindbrain development GO:0030902 65 32 1,000 9,922E-03 0,05841066 ! myeloid leukocyte activation GO:0002274 53 32 1,000 9,922E-03 0,05827025 ! regulation of membrane potential GO:0042391 179 94 2,000 9,991E-03 0,05853276 ! regulation of defense response GO:0031347 171 95 2,000 0,01028186 0,06009231 ! regulation of pH GO:0006885 56 33 1,000 0,01053023 0,06139701 ! response to ionizing radiation GO:0010212 74 33 1,000 0,01053023 0,06125083 ! regulation of axonogenesis GO:0050770 86 33 1,000 0,01053023 0,06110534 ! regulation of DNA metabolic process GO:0051052 188 97 2,000 0,01087811 0,06297449 ! cell fate specification GO:0001708 56 34 1,000 0,01115414 0,06441977 ! symbiosis, encompassing mutualism through parasitism GO:0044403 79 34 1,000 0,01115414 0,06426784 ! negative regulation of DNA metabolic process GO:0051053 65 35 1,000 0,01179397 0,06779451 ! DNA damage checkpoint GO:0000077 78 35 1,000 0,01179397 0,06763537 ! regulation of synaptic plasticity GO:0048167 78 35 1,000 0,01179397 0,06747697 ! regulation of striated muscle tissue development GO:0016202 81 35 1,000 0,01179397 0,06731932 ! multicellular organismal macromolecule metabolic process GO:0044259 54 35 1,000 0,01179397 0,06716239 ! calcium-mediated signaling GO:0019722 67 35 1,000 0,01179397 0,0670062 ! skeletal muscle tissue development GO:0007519 223 100 2,000 0,01180934 0,06693784 GO:0060538|skeletal muscle organ development, ! regulation of muscle development GO:0048634 82 36 1,000 0,01244956 0,0704034 ! mitotic sister chromatid segregation GO:0000070 63 36 1,000 0,01244956 0,0702408 ! negative regulation of DNA binding GO:0043392 67 36 1,000 0,01244956 0,07007896 ! negative regulation of hydrolase activity GO:0051346 66 36 1,000 0,01244956 0,06991786 ! embryonic organ development GO:0048568 67 36 1,000 0,01244956 0,0697575 ! monosaccharide biosynthetic process GO:0046364 57 36 1,000 0,01244956 0,06959787 ! regulation of smooth muscle cell proliferation GO:0048660 64 37 1,000 0,01312074 0,07318259 ! negative regulation of cell adhesion GO:0007162 94 37 1,000 0,01312074 0,07301589 ! xenobiotic metabolic process GO:0006805 55 37 1,000 0,01312074 0,07284994 ! sister chromatid segregation GO:0000819 65 37 1,000 0,01312074 0,07268475 ! cell junction organization GO:0034330 96 37 1,000 0,01312074 0,0725203 ! regulation of microtubule-based process GO:0032886 86 37 1,000 0,01312074 0,0723566 ! positive regulation of DNA metabolic process GO:0051054 77 38 1,000 0,01380737 0,07597162 ! cellular component assembly involved in morphogenesis GO:0010927 65 38 1,000 0,01380737 0,07580089 ! meiosis I GO:0007127 74 38 1,000 0,01380737 0,07563094 ! DNA integrity checkpoint GO:0031570 82 38 1,000 0,01380737 0,07546174 ! regulation of Wnt receptor signaling pathway GO:0030111 78 38 1,000 0,01380737 0,0752933 ! regulation of protein stability GO:0031647 77 38 1,000 0,01380737 0,07512561 ! glycogen metabolic process GO:0005977 63 38 1,000 0,01380737 0,07495866 ! cellular response to insulin stimulus GO:0032869 85 38 1,000 0,01380737 0,07479245 ! neural tube formation GO:0001841 79 38 1,000 0,01380737 0,07462698 ! regulation of neuron projection development GO:0010975 102 39 1,000 0,01450927 0,07824757 ! negative regulation of binding GO:0051100 71 39 1,000 0,01450927 0,07807522 ! mitotic cell cycle checkpoint GO:0007093 76 39 1,000 0,01450927 0,07790363 ! positive regulation of leukocyte proliferation GO:0070665 70 39 1,000 0,01450927 0,07773278 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! regulation of cell morphogenesis involved in differentiation GO:0010769 101 39 1,000 0,01450927 0,07756269 ! glucan metabolic process GO:0044042 64 39 1,000 0,01450927 0,07739334 GO:0006073|cellular glucan metabolic process, ! mammary gland development GO:0030879 93 40 1,000 0,0152263 0,08104106 ! learning GO:0007612 82 40 1,000 0,0152263 0,08086489 ! nucleus organization GO:0006997 73 40 1,000 0,0152263 0,08068948 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 75 41 1,000 0,01595829 0,08438553 ! multicellular organismal metabolic process GO:0044236 64 41 1,000 0,01595829 0,08420327 ! mesenchymal cell development GO:0014031 94 41 1,000 0,01595829 0,0840218 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! monovalent inorganic cation homeostasis GO:0055067 72 41 1,000 0,01595829 0,0838411 ! embryonic epithelial tube formation GO:0001838 85 41 1,000 0,01595829 0,08366119 ! alcohol biosynthetic process GO:0046165 65 42 1,000 0,0167051 0,08738879 ! dorsal/ventral pattern formation GO:0009953 75 42 1,000 0,0167051 0,08720206 ! cytokinesis GO:0000910 84 42 1,000 0,0167051 0,08701613 ! positive regulation of transcription factor activity GO:0051091 71 43 1,000 0,01746657 0,090789 GO:0090047|positive regulation of transcription regulator activity, ! development of primary male sexual characteristics GO:0046546 80 43 1,000 0,01746657 0,09059624 ! segmentation GO:0035282 78 43 1,000 0,01746657 0,0904043 ! neuron migration GO:0001764 85 43 1,000 0,01746657 0,09021317 ! energy reserve metabolic process GO:0006112 76 44 1,000 0,01824254 0,09402223 ! negative regulation of protein complex disassembly GO:0043242 113 44 1,000 0,01824254 0,09382429 ! double-strand break repair GO:0006302 85 44 1,000 0,01824254 0,09362718 ! branching morphogenesis of a tube GO:0048754 102 45 1,000 0,01903287 0,09747864 ! B cell differentiation GO:0030183 124 45 1,000 0,01903287 0,09727471 ! positive regulation of cytokine biosynthetic process GO:0042108 76 46 1,000 0,01983741 0,10117493 ! pigmentation GO:0043473 103 46 1,000 0,01983741 0,10096415 ! positive regulation of protein transport GO:0051222 80 46 1,000 0,01983741 0,10075424 ! response to insulin stimulus GO:0032868 98 47 1,000 0,020656 0,10469421 ! mitochondrial transport GO:0006839 94 48 1,000 0,0214885 0,1086882 ! cellular component disassembly GO:0022411 89 48 1,000 0,0214885 0,10846364 ! positive regulation of DNA binding GO:0043388 83 48 1,000 0,0214885 0,10824 ! vascular process in circulatory system GO:0003018 85 48 1,000 0,0214885 0,10801729 ! male sex differentiation GO:0046661 93 48 1,000 0,0214885 0,10779548 ! negative regulation of protein ubiquitination GO:0031397 10 5 0,000 0,02327359 0,11651104 ! negative regulation of nucleotide biosynthetic process GO:0030809 11 5 0,000 0,02327359 0,11627277 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of muscle development GO:0048636 15 5 0,000 0,02327359 0,11603548 GO:0045844|positive regulation of striated muscle development, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,02327359 0,11579916 ! positive regulation of helicase activity GO:0051096 12 5 0,000 0,02327359 0,11556379 ! neuron fate determination GO:0048664 7 5 0,000 0,02327359 0,11532938 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02327359 0,11509592 ! regulation of cGMP biosynthetic process GO:0030826 10 5 0,000 0,02327359 0,11486341 ! polyol transport GO:0015791 12 5 0,000 0,02327359 0,11463183 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,02327359 0,11440118 ! response to superoxide GO:0000303 10 5 0,000 0,02327359 0,11417146 ! positive regulation of lipid biosynthetic process GO:0046889 11 5 0,000 0,02327359 0,11394266 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 10 5 0,000 0,02327359 0,11371477 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,02327359 0,1134878 ! female meiosis GO:0007143 10 5 0,000 0,02327359 0,11326172 ! cell adhesion mediated by integrin GO:0033627 10 5 0,000 0,02327359 0,11303655 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,02327359 0,11281227 ! hypothalamus development GO:0021854 9 5 0,000 0,02327359 0,11258888 ! phosphatidic acid metabolic process GO:0046473 6 5 0,000 0,02327359 0,11236637 ! cobalt ion transport GO:0006824 11 5 0,000 0,02327359 0,11214474 ! cellular sodium ion homeostasis GO:0006883 11 5 0,000 0,02327359 0,11192399 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 16 5 0,000 0,02327359 0,1117041 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,02327359 0,11148507 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,02327359 0,1112669 ! regulation of cardiac muscle cell proliferation GO:0060043 9 5 0,000 0,02327359 0,11104958 ! embryonic camera-type eye development GO:0031076 12 5 0,000 0,02327359 0,11083311 GO:0048596|embryonic camera-type eye morphogenesis, ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02327359 0,11061748 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 7 5 0,000 0,02327359 0,11040269 ! transposition GO:0032196 9 5 0,000 0,02327359 0,11018873 ! 2-oxoglutarate metabolic process GO:0006103 10 5 0,000 0,02327359 0,1099756 ! negative chemotaxis GO:0050919 16 5 0,000 0,02327359 0,10976329 ! positive regulation of histone modification GO:0031058 6 5 0,000 0,02327359 0,1095518 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,02327359 0,10934113 ! negative regulation of receptor-mediated endocytosis GO:0048261 6 5 0,000 0,02327359 0,10913126 ! behavioral response to pain GO:0048266 10 5 0,000 0,02327359 0,10892219 ! clathrin coat assembly GO:0048268 15 5 0,000 0,02327359 0,10871393 ! Notch receptor processing GO:0007220 11 5 0,000 0,02327359 0,10850646 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02327359 0,10829978 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! micturition GO:0060073 9 5 0,000 0,02327359 0,10809389 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,02327359 0,10788878 ! copulation GO:0007620 9 5 0,000 0,02327359 0,10768444 ! glial cell fate commitment GO:0021781 14 5 0,000 0,02327359 0,10748088 ! protein maturation by protein folding GO:0022417 14 5 0,000 0,02327359 0,10727809 ! bioluminescence GO:0008218 9 5 0,000 0,02327359 0,10707606 ! spermidine metabolic process GO:0008216 7 5 0,000 0,02327359 0,10687478 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,02327359 0,10667427 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,02327359 0,1064745 ! apoptotic cell clearance GO:0043277 23 5 0,000 0,02327359 0,10627549 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,02327359 0,10607721 ! smooth muscle cell differentiation GO:0051145 8 5 0,000 0,02327359 0,10587968 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,02327359 0,10568287 ! grooming behavior GO:0007625 6 5 0,000 0,02327359 0,1054868 ! detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 6 5 0,000 0,02327359 0,10529145 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,02327359 0,10509683 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 12 5 0,000 0,02327359 0,10490293 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02327359 0,10470973 ! response to protozoan GO:0001562 13 5 0,000 0,02327359 0,10451725 ! lymph vessel development GO:0001945 10 5 0,000 0,02327359 0,10432548 ! regulation of activin receptor signaling pathway GO:0032925 15 5 0,000 0,02327359 0,10413441 ! endochondral ossification GO:0001958 17 5 0,000 0,02327359 0,10394403 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,02327359 0,10375435 ! single strand break repair GO:0000012 8 5 0,000 0,02327359 0,10356537 ! parathyroid gland development GO:0060017 14 5 0,000 0,02327359 0,10337706 ! anagen GO:0042640 7 5 0,000 0,02327359 0,10318945 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,02327359 0,10300251 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,02327359 0,10281625 ! cytokine secretion GO:0050663 15 5 0,000 0,02327359 0,10263066 ! hydrogen peroxide biosynthetic process GO:0050665 8 5 0,000 0,02327359 0,10244574 ! ceramide catabolic process GO:0046514 7 5 0,000 0,02327359 0,10226148 ! skeletal myofibril assembly GO:0014866 12 5 0,000 0,02327359 0,10207789 ! smooth muscle tissue development GO:0048745 32 5 0,000 0,02327359 0,10189496 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,02327359 0,10171268 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,02327359 0,10153105 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,02327359 0,10135006 ! cardiac muscle fiber development GO:0048739 12 5 0,000 0,02327359 0,10116973 ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,02327359 0,10099003 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! negative regulation of survival gene product expression GO:0008634 9 5 0,000 0,02327359 0,10081097 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,02327359 0,10063254 ! cellular di-, tri-valent inorganic anion homeostasis GO:0030319 10 5 0,000 0,02327359 0,10045474 GO:0030643|cellular phosphate ion homeostasis, GO:0055062|phosphate ion homeostasis, GO:0055061|di-, tri-valent inorganic anion homeostasis, ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,02327359 0,10027758 ! negative regulation of RNA splicing GO:0033119 6 5 0,000 0,02327359 0,10010103 ! glycine biosynthetic process GO:0006545 7 5 0,000 0,02327359 0,09992511 ! valine metabolic process GO:0006573 12 5 0,000 0,02327359 0,0997498 ! endoplasmic reticulum organization GO:0007029 12 5 0,000 0,02327359 0,09957511 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 16 5 0,000 0,02327359 0,09940102 ! assembly of spliceosomal tri-snRNP GO:0000244 8 5 0,000 0,02327359 0,09922755 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 7 5 0,000 0,02327359 0,09905468 ! immunoglobulin V(D)J recombination GO:0033152 25 5 0,000 0,02327359 0,09888241 ! polyol catabolic process GO:0046174 9 5 0,000 0,02327359 0,09871074 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 6 5 0,000 0,02327359 0,09853966 ! melanin biosynthetic process from tyrosine GO:0006583 8 5 0,000 0,02327359 0,09836918 ! regulation of cardiac muscle contraction GO:0055117 6 5 0,000 0,02327359 0,09819928 ! muscle cell migration GO:0014812 8 5 0,000 0,02327359 0,09802998 ! mitochondrial fission GO:0000266 8 5 0,000 0,02327359 0,09786125 ! sister chromatid cohesion GO:0007062 15 5 0,000 0,02327359 0,0976931 ! response to tumor necrosis factor GO:0034612 10 5 0,000 0,02327359 0,09752553 ! nerve growth factor processing GO:0032455 9 5 0,000 0,02327359 0,09735854 ! positive regulation of filopodium assembly GO:0051491 16 5 0,000 0,02327359 0,09719211 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 8 5 0,000 0,02327359 0,09702626 ! anaerobic glycolysis GO:0019642 6 5 0,000 0,02327359 0,09686096 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,02327359 0,09669623 ! monocyte activation GO:0042117 10 5 0,000 0,02327359 0,09653206 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,02327359 0,09636845 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,02327359 0,09620539 ! response to food GO:0032094 6 5 0,000 0,02327359 0,09604288 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,02327359 0,09588092 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,02327359 0,0957195 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 10 5 0,000 0,02327359 0,09555863 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02327359 0,0953983 ! forebrain neuron development GO:0021884 13 5 0,000 0,02327359 0,0952385 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,02327359 0,09507924 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 10 5 0,000 0,02327359 0,09492051 ! virus-infected cell apoptosis GO:0006926 7 5 0,000 0,02327359 0,09476231 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,02327359 0,09460463 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02327359 0,09444748 GO:0009251|glucan catabolic process, ! entrainment of circadian clock GO:0009649 12 5 0,000 0,02327359 0,09429085 ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,02327359 0,09413474 ! peptidyl-histidine phosphorylation GO:0018106 10 5 0,000 0,02327359 0,09397915 ! lipid glycosylation GO:0030259 7 5 0,000 0,02327359 0,09382407 ! nucleobase transport GO:0015851 6 5 0,000 0,02327359 0,0936695 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02327359 0,09351544 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! establishment of synaptic specificity at neuromuscular junction GO:0007529 8 5 0,000 0,02327359 0,09336188 ! positive regulation of vasoconstriction GO:0045907 10 5 0,000 0,02327359 0,09320883 ! positive regulation of fatty acid metabolic process GO:0045923 14 5 0,000 0,02327359 0,09305628 ! basic amino acid transport GO:0015802 12 5 0,000 0,02327359 0,09290422 ! cellular glucose homeostasis GO:0001678 6 5 0,000 0,02327359 0,09275267 ! heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 13 5 0,000 0,02327359 0,09260161 ! actin nucleation GO:0045010 11 5 0,000 0,02327359 0,09245103 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,02327359 0,09230095 ! depurination GO:0045007 5 5 0,000 0,02327359 0,09215135 ! depyrimidination GO:0045008 10 5 0,000 0,02327359 0,09200224 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,02327359 0,09185361 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02327359 0,09170546 ! G2/M transition checkpoint GO:0031576 8 5 0,000 0,02327359 0,09155779 GO:0031572|G2/M transition DNA damage checkpoint, ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,02327359 0,09141059 ! zinc ion homeostasis GO:0055069 9 5 0,000 0,02327359 0,09126386 GO:0006882|cellular zinc ion homeostasis, ! nucleoside monophosphate catabolic process GO:0009125 14 5 0,000 0,02327359 0,09111761 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02327359 0,09097182 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,02327359 0,09082649 ! activated T cell proliferation GO:0050798 16 5 0,000 0,02327359 0,09068164 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,02327359 0,09053724 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 11 5 0,000 0,02327359 0,0903933 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,02327359 0,09024982 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02327359 0,09010679 ! gamma-delta T cell activation GO:0046629 6 5 0,000 0,02327359 0,08996422 ! response to arsenic GO:0046685 11 5 0,000 0,02327359 0,08982209 ! negative regulation of T cell mediated immunity GO:0002710 15 5 0,000 0,02327359 0,08968042 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,02327359 0,08953919 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 8 5 0,000 0,02327359 0,0893984 ! L-ascorbic acid metabolic process GO:0019852 10 5 0,000 0,02327359 0,08925806 ! base-excision repair, DNA ligation GO:0006288 6 5 0,000 0,02327359 0,08911816 ! response to cadmium ion GO:0046686 7 5 0,000 0,02327359 0,08897869 ! tetrahydrofolate metabolic process GO:0046653 7 5 0,000 0,02327359 0,08883966 ! UDP-N-acetylgalactosamine metabolic process GO:0019276 5 5 0,000 0,02327359 0,08870107 ! DNA replication, synthesis of RNA primer GO:0006269 8 5 0,000 0,02327359 0,08856291 ! bile acid biosynthetic process GO:0006699 7 5 0,000 0,02327359 0,08842517 ! sphingomyelin catabolic process GO:0006685 7 5 0,000 0,02327359 0,08828787 ! ganglioside catabolic process GO:0006689 12 5 0,000 0,02327359 0,08815099 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,02327359 0,08801453 ! decidualization GO:0046697 11 5 0,000 0,02327359 0,08787849 ! platelet activating factor biosynthetic process GO:0006663 7 5 0,000 0,02327359 0,08774288 ! positive regulation of interleukin-4 production GO:0032753 9 5 0,000 0,02327359 0,08760768 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 8 5 0,000 0,02327359 0,0874729 ! regulation of chondrocyte differentiation GO:0032330 16 5 0,000 0,02327359 0,08733853 ! embryonic cleavage GO:0040016 6 5 0,000 0,02327359 0,08720458 ! peroxisome fission GO:0016559 5 5 0,000 0,02327359 0,08707103 ! histone demethylation GO:0016577 13 5 0,000 0,02327359 0,0869379 ! reproductive behavior in a multicellular organism GO:0033057 17 5 0,000 0,02327359 0,08680517 ! mitotic recombination GO:0006312 9 5 0,000 0,02327359 0,08667284 ! spinal cord association neuron differentiation GO:0021527 9 5 0,000 0,02327359 0,08654092 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,02327359 0,0864094 ! metaphase plate congression GO:0051310 7 5 0,000 0,02327359 0,08627828 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02327359 0,08614755 GO:0032374|regulation of cholesterol transport, ! enteric nervous system development GO:0048484 8 5 0,000 0,02327359 0,08601722 ! indolalkylamine catabolic process GO:0046218 8 5 0,000 0,02327359 0,08588729 GO:0006569|tryptophan catabolic process, GO:0042436|indole derivative catabolic process, ! lymphocyte costimulation GO:0031294 8 5 0,000 0,02327359 0,08575775 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 12 5 0,000 0,02327359 0,08562859 ! muscle cell proliferation GO:0033002 12 5 0,000 0,02327359 0,08549983 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,02327359 0,08537145 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 16 5 0,000 0,02327359 0,08524346 ! B cell homeostasis GO:0001782 13 5 0,000 0,02327359 0,08511585 ! positive regulation of Wnt receptor signaling pathway GO:0030177 13 5 0,000 0,02327359 0,08498862 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,02327359 0,08486177 ! metaphase GO:0051323 11 5 0,000 0,02327359 0,0847353 ! melatonin biosynthetic process GO:0030187 7 5 0,000 0,02327359 0,0846092 GO:0030186|melatonin metabolic process, ! positive regulation of blood coagulation GO:0030194 12 5 0,000 0,02327359 0,08448349 ! cellular response to nutrient GO:0031670 8 5 0,000 0,02327359 0,08435814 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,02327359 0,08423316 ! regulation of muscle cell apoptosis GO:0010660 7 5 0,000 0,02327359 0,08410856 ! ATP-dependent chromatin remodeling GO:0043044 10 5 0,000 0,02327359 0,08398432 ! regulation of hair follicle development GO:0051797 10 5 0,000 0,02327359 0,08386045 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 14 5 0,000 0,02327359 0,08373694 ! response to redox state GO:0051775 6 5 0,000 0,02327359 0,0836138 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 7 5 0,000 0,02327359 0,08349102 ! glucocorticoid biosynthetic process GO:0006704 7 5 0,000 0,02327359 0,0833686 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,02327359 0,08324654 ! brown fat cell differentiation GO:0050873 7 5 0,000 0,02327359 0,08312483 ! regulation of telomerase activity GO:0051972 7 5 0,000 0,02327359 0,08300348 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02327359 0,08288249 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 15 5 0,000 0,02327359 0,08276184 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02327359 0,08264155 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 15 5 0,000 0,02327359 0,0825216 ! striatum development GO:0021756 14 5 0,000 0,02327359 0,08240201 ! positive regulation of T cell mediated cytotoxicity GO:0001916 15 5 0,000 0,02327359 0,08228276 ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,02327359 0,08216385 ! glial cell migration GO:0008347 10 5 0,000 0,02327359 0,08204529 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,02327359 0,08192707 ! neural plate morphogenesis GO:0001839 7 5 0,000 0,02327359 0,08180919 ! regulation of mitochondrial depolarization GO:0051900 14 5 0,000 0,02327359 0,08169165 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,02327359 0,08157444 ! T cell activation during immune response GO:0002286 9 5 0,000 0,02327359 0,08145757 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,02327359 0,08134104 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,02327359 0,08122484 ! innate immune response activating cell surface receptor signaling pathway GO:0002220 7 5 0,000 0,02327359 0,08110897 ! neuroprotection GO:0043526 8 5 0,000 0,02327359 0,08099343 ! regulation of sensory perception GO:0051931 8 5 0,000 0,02327359 0,08087822 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,02327359 0,08076333 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,02327359 0,08064877 ! positive regulation of actin filament bundle formation GO:0032233 18 5 0,000 0,02327359 0,08053454 ! negative regulation of actin filament bundle formation GO:0032232 17 5 0,000 0,02327359 0,08042063 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,02327359 0,08030704 ! diacylglycerol metabolic process GO:0046339 7 5 0,000 0,02327359 0,08019377 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,02327359 0,08008082 ! release of sequestered calcium ion into cytosol GO:0051209 14 5 0,000 0,02327359 0,07996819 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! inner ear receptor stereocilium organization GO:0060122 12 5 0,000 0,02327359 0,07985588 GO:0060119|inner ear receptor cell development, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,02327359 0,07974388 ! spindle assembly GO:0051225 6 5 0,000 0,02327359 0,07963219 ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,02327359 0,07952082 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,02327359 0,07940976 ! protein palmitoylation GO:0018345 12 5 0,000 0,02327359 0,079299 ! drug metabolic process GO:0017144 7 5 0,000 0,02327359 0,07918856 ! phospholipid scrambling GO:0017121 8 5 0,000 0,02327359 0,07907842 ! organ regeneration GO:0031100 7 5 0,000 0,02327359 0,07896859 ! carnitine metabolic process GO:0009437 8 5 0,000 0,02327359 0,07885906 GO:0006577|betaine metabolic process, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,02327359 0,07874984 ! regulation of cell projection organization GO:0031344 135 51 1,000 0,02406797 0,08132512 ! response to temperature stimulus GO:0009266 84 51 1,000 0,02406797 0,08121279 ! positive regulation of binding GO:0051099 88 52 1,000 0,02495464 0,08408854 ! Notch signaling pathway GO:0007219 111 52 1,000 0,02495464 0,08397272 ! regulation of protein complex disassembly GO:0043244 127 52 1,000 0,02495464 0,08385721 ! morphogenesis of embryonic epithelium GO:0016331 106 52 1,000 0,02495464 0,08374202 ! morphogenesis of a branching structure GO:0001763 116 52 1,000 0,02495464 0,08362715 ! positive regulation of growth GO:0045927 96 53 1,000 0,02585449 0,08652401 ! chromatin remodeling GO:0006338 122 53 1,000 0,02585449 0,08640565 ! regulation of neuron apoptosis GO:0043523 117 53 1,000 0,02585449 0,08628761 ! synapse organization GO:0050808 102 53 1,000 0,02585449 0,08616989 ! regulation of translational initiation GO:0006446 87 54 1,000 0,02676739 0,08909091 ! membrane fusion GO:0006944 122 54 1,000 0,02676739 0,08896969 ! regulation of cell shape GO:0008360 142 54 1,000 0,02676739 0,08884881 ! epithelial tube morphogenesis GO:0060562 114 54 1,000 0,02676739 0,08872826 ! cell recognition GO:0008037 98 55 1,000 0,02769318 0,09167268 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,02786329 0,09211099 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,02786329 0,09198651 ! negative regulation of S phase of mitotic cell cycle GO:0045749 12 6 0,000 0,02786329 0,09186238 ! positive regulation of cAMP biosynthetic process GO:0030819 13 6 0,000 0,02786329 0,09173857 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,02786329 0,0916151 ! oligosaccharide biosynthetic process GO:0009312 11 6 0,000 0,02786329 0,09149196 ! regulation of cGMP metabolic process GO:0030823 12 6 0,000 0,02786329 0,09136915 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,02786329 0,09124668 ! post-embryonic morphogenesis GO:0009886 9 6 0,000 0,02786329 0,09112452 ! response to oxygen radical GO:0000305 11 6 0,000 0,02786329 0,0910027 ! positive regulation of axon extension GO:0045773 13 6 0,000 0,02786329 0,0908812 ! myoblast cell fate commitment GO:0048625 18 6 0,000 0,02786329 0,09076003 ! negative regulation of small GTPase mediated signal transduction GO:0051058 19 6 0,000 0,02786329 0,09063917 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 10 6 0,000 0,02786329 0,09051864 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,02786329 0,09039843 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! virion attachment to host cell surface receptor GO:0019062 16 6 0,000 0,02786329 0,09027854 ! forebrain regionalization GO:0021871 9 6 0,000 0,02786329 0,09015897 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,02786329 0,09003971 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,02786329 0,08992077 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 12 6 0,000 0,02786329 0,08980214 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,02786329 0,08968382 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 27 6 0,000 0,02786329 0,08956582 ! regulation of respiratory gaseous exchange GO:0043576 9 6 0,000 0,02786329 0,08944812 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,02786329 0,08933073 ! negative regulation of cell-cell adhesion GO:0022408 13 6 0,000 0,02786329 0,08921366 ! positive regulation of cell-cell adhesion GO:0022409 15 6 0,000 0,02786329 0,08909688 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,02786329 0,08898042 ! malate metabolic process GO:0006108 13 6 0,000 0,02786329 0,08886426 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 7 6 0,000 0,02786329 0,0887484 GO:0050907|detection of chemical stimulus involved in sensory perception, ! sensory perception of bitter taste GO:0050913 9 6 0,000 0,02786329 0,08863284 ! posttranscriptional gene silencing by RNA GO:0035194 20 6 0,000 0,02786329 0,08851758 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 10 6 0,000 0,02786329 0,08840262 ! protein refolding GO:0042026 15 6 0,000 0,02786329 0,08828796 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,02786329 0,0881736 ! opsonization GO:0008228 8 6 0,000 0,02786329 0,08805953 ! mating behavior GO:0007617 7 6 0,000 0,02786329 0,08794576 ! erythrocyte maturation GO:0043249 8 6 0,000 0,02786329 0,08783228 ! protein amino acid dealkylation GO:0008214 15 6 0,000 0,02786329 0,0877191 GO:0006482|protein amino acid demethylation, ! photoreceptor cell development GO:0042461 10 6 0,000 0,02786329 0,0876062 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 12 6 0,000 0,02786329 0,0874936 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,02786329 0,08738128 ! response to interferon-gamma GO:0034341 16 6 0,000 0,02786329 0,08726926 ! toxin metabolic process GO:0009404 11 6 0,000 0,02786329 0,08715752 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,02786329 0,08704606 ! traversing start control point of mitotic cell cycle GO:0007089 14 6 0,000 0,02786329 0,08693489 ! spinal cord dorsal/ventral patterning GO:0021513 13 6 0,000 0,02786329 0,08682401 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 13 6 0,000 0,02786329 0,0867134 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! nuclear migration GO:0007097 13 6 0,000 0,02786329 0,08660308 ! cGMP-mediated signaling GO:0019934 14 6 0,000 0,02786329 0,08649304 ! dorsal spinal cord development GO:0021516 10 6 0,000 0,02786329 0,08638327 ! activation of MAPKKK activity GO:0000185 12 6 0,000 0,02786329 0,08627379 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 15 6 0,000 0,02786329 0,08616458 ! thymic T cell selection GO:0045061 16 6 0,000 0,02786329 0,08605565 ! sphingoid catabolic process GO:0046521 8 6 0,000 0,02786329 0,08594699 ! protein lipoylation GO:0009249 10 6 0,000 0,02786329 0,08583861 ! transepithelial chloride transport GO:0030321 12 6 0,000 0,02786329 0,0857305 GO:0070633|transepithelial transport, ! regulation of retroviral genome replication GO:0045091 8 6 0,000 0,02786329 0,08562267 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,02786329 0,0855151 ! regulation of isotype switching to IgG isotypes GO:0048302 11 6 0,000 0,02786329 0,0854078 ! glutamate catabolic process GO:0006538 12 6 0,000 0,02786329 0,08530078 ! mitochondrial respiratory chain complex assembly GO:0033108 11 6 0,000 0,02786329 0,08519402 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,02786329 0,08508753 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! positive regulation of peptidyl-serine phosphorylation GO:0033138 12 6 0,000 0,02786329 0,0849813 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,02786329 0,08487534 ! hyperosmotic response GO:0006972 10 6 0,000 0,02786329 0,08476964 ! L-serine biosynthetic process GO:0006564 7 6 0,000 0,02786329 0,0846642 ! chromatin-mediated maintenance of transcription GO:0048096 17 6 0,000 0,02786329 0,08455903 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 11 6 0,000 0,02786329 0,08445412 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,02786329 0,08434947 ! urea metabolic process GO:0019627 7 6 0,000 0,02786329 0,08424507 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,02786329 0,08414094 ! neutrophil activation GO:0042119 7 6 0,000 0,02786329 0,08403706 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,02786329 0,08393344 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 10 6 0,000 0,02786329 0,08383007 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,02786329 0,08372696 ! paraxial mesoderm development GO:0048339 16 6 0,000 0,02786329 0,0836241 ! positive regulation of multicellular organismal metabolic process GO:0044253 8 6 0,000 0,02786329 0,0835215 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,02786329 0,08341914 ! neuron apoptosis GO:0051402 15 6 0,000 0,02786329 0,08331704 ! T cell mediated immunity GO:0002456 17 6 0,000 0,02786329 0,08321518 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,02786329 0,08311358 GO:0010543|regulation of platelet activation, ! folic acid transport GO:0015884 14 6 0,000 0,02786329 0,08301222 ! carnitine transport GO:0015879 10 6 0,000 0,02786329 0,08291111 GO:0015838|betaine transport, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02786329 0,08281024 ! positive regulation of exocytosis GO:0045921 11 6 0,000 0,02786329 0,08270962 ! protein import into mitochondrial inner membrane GO:0045039 9 6 0,000 0,02786329 0,08260925 ! early endosome to late endosome transport GO:0045022 16 6 0,000 0,02786329 0,08250912 ! 5S class rRNA transcription GO:0042791 13 6 0,000 0,02786329 0,08240923 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,02786329 0,08230958 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 15 6 0,000 0,02786329 0,08221017 ! regulation of collagen metabolic process GO:0010712 10 6 0,000 0,02786329 0,082111 ! sodium ion homeostasis GO:0055078 12 6 0,000 0,02786329 0,08201207 ! deoxyribonucleoside metabolic process GO:0009120 11 6 0,000 0,02786329 0,08191338 ! negative regulation of gliogenesis GO:0014014 18 6 0,000 0,02786329 0,08181493 GO:0045686|negative regulation of glial cell differentiation, ! neural nucleus development GO:0048857 19 6 0,000 0,02786329 0,08171671 ! response to UV-C GO:0010225 14 6 0,000 0,02786329 0,08161873 ! astrocyte development GO:0014002 16 6 0,000 0,02786329 0,08152098 ! protein targeting to lysosome GO:0006622 12 6 0,000 0,02786329 0,08142347 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,02786329 0,08132619 ! interaction with symbiont GO:0051702 14 6 0,000 0,02786329 0,08122914 ! regulation of dendrite development GO:0050773 16 6 0,000 0,02786329 0,08113232 ! peptidyl-arginine modification GO:0018195 13 6 0,000 0,02786329 0,08103574 ! positive regulation of cytokine production during immune response GO:0002720 11 6 0,000 0,02786329 0,08093938 ! response to copper ion GO:0046688 10 6 0,000 0,02786329 0,08084325 ! response to exogenous dsRNA GO:0043330 13 6 0,000 0,02786329 0,08074735 ! enucleate erythrocyte differentiation GO:0043353 14 6 0,000 0,02786329 0,08065168 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02786329 0,08055624 ! regulation of interleukin-5 production GO:0032674 10 6 0,000 0,02786329 0,08046102 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,02786329 0,08036602 ! positive regulation of B cell differentiation GO:0045579 13 6 0,000 0,02786329 0,08027125 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,02786329 0,0801767 ! nucleoside catabolic process GO:0009164 10 6 0,000 0,02786329 0,08008238 ! hair follicle maturation GO:0048820 8 6 0,000 0,02786329 0,07998827 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,02786329 0,07989439 ! Schwann cell development GO:0014044 15 6 0,000 0,02786329 0,07980073 ! CD4-positive, alpha beta T cell differentiation GO:0043367 11 6 0,000 0,02786329 0,07970728 ! response to pheromone GO:0019236 6 6 0,000 0,02786329 0,07961406 ! purine deoxyribonucleotide catabolic process GO:0009155 6 6 0,000 0,02786329 0,07952105 ! regulation of myeloid cell apoptosis GO:0033032 14 6 0,000 0,02786329 0,07942826 ! base conversion or substitution editing GO:0016553 6 6 0,000 0,02786329 0,07933569 ! subpallium development GO:0021544 15 6 0,000 0,02786329 0,07924333 ! negative regulation of multicellular organism growth GO:0040015 9 6 0,000 0,02786329 0,07915119 ! regulation of myeloid leukocyte mediated immunity GO:0002886 9 6 0,000 0,02786329 0,07905926 ! maintenance of organ identity GO:0048496 9 6 0,000 0,02786329 0,07896754 ! G2 phase GO:0051319 16 6 0,000 0,02786329 0,07887604 GO:0000085|G2 phase of mitotic cell cycle, ! indolalkylamine biosynthetic process GO:0046219 8 6 0,000 0,02786329 0,07878475 GO:0042435|indole derivative biosynthetic process, ! tetracycline transport GO:0015904 8 6 0,000 0,02786329 0,07869366 ! establishment of planar polarity GO:0001736 7 6 0,000 0,02786329 0,07860279 ! regulation of mast cell activation GO:0033003 13 6 0,000 0,02786329 0,07851213 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,02786329 0,07842168 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 10 6 0,000 0,02786329 0,07833144 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,02786329 0,0782414 ! receptor internalization GO:0031623 11 6 0,000 0,02786329 0,07815157 ! positive regulation of pseudopodium assembly GO:0031274 15 6 0,000 0,02786329 0,07806195 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 9 6 0,000 0,02786329 0,07797253 ! neutrophil homeostasis GO:0001780 11 6 0,000 0,02786329 0,07788332 ! salivary gland morphogenesis GO:0007435 14 6 0,000 0,02786329 0,07779431 ! protein deubiquitination GO:0016579 16 6 0,000 0,02786329 0,0777055 ! protein destabilization GO:0031648 9 6 0,000 0,02786329 0,0776169 ! regulation of hydrogen peroxide metabolic process GO:0010310 7 6 0,000 0,02786329 0,0775285 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,02786329 0,0774403 ! positive regulation of T-helper 1 cell differentiation GO:0045627 9 6 0,000 0,02786329 0,0773523 ! regulation of viral transcription GO:0046782 11 6 0,000 0,02786329 0,07726449 ! progesterone metabolic process GO:0042448 12 6 0,000 0,02786329 0,07717689 ! activation of Ras GTPase activity GO:0032856 13 6 0,000 0,02786329 0,07708949 GO:0032862|activation of Rho GTPase activity, ! removal of superoxide radicals GO:0019430 12 6 0,000 0,02786329 0,07700229 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,02786329 0,07691528 ! determination of adult lifespan GO:0008340 17 6 0,000 0,02786329 0,07682847 ! ectodermal gut morphogenesis GO:0048567 16 6 0,000 0,02786329 0,07674185 GO:0007439|ectodermal gut development, ! cerebellar cortex formation GO:0021697 8 6 0,000 0,02786329 0,07665543 ! neural plate development GO:0001840 9 6 0,000 0,02786329 0,0765692 ! catecholamine transport GO:0051937 9 6 0,000 0,02786329 0,07648317 ! negative regulation of NF-kappaB import into nucleus GO:0042347 15 6 0,000 0,02786329 0,07639733 ! sensory cilium assembly GO:0035058 10 6 0,000 0,02786329 0,07631168 ! organ or tissue specific immune response GO:0002251 8 6 0,000 0,02786329 0,07622623 ! cytoplasmic microtubule organization GO:0031122 18 6 0,000 0,02786329 0,07614096 ! regulation of T cell receptor signaling pathway GO:0050856 11 6 0,000 0,02786329 0,07605589 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,02786329 0,075971 ! metallo-sulfur cluster assembly GO:0031163 6 6 0,000 0,02786329 0,07588631 GO:0016226|iron-sulfur cluster assembly, ! negative regulation of synaptic transmission GO:0050805 14 6 0,000 0,02786329 0,0758018 ! positive regulation of coagulation GO:0050820 13 6 0,000 0,02786329 0,07571749 ! cellular anion homeostasis GO:0030002 11 6 0,000 0,02786329 0,07563336 GO:0055081|anion homeostasis, ! skeletal muscle fiber development GO:0048741 130 56 1,000 0,02863173 0,07763299 ! negative regulation of cytoskeleton organization GO:0051494 139 56 1,000 0,02863173 0,07754692 ! regulation of protein catabolic process GO:0042176 126 56 1,000 0,02863173 0,07746104 ! regulation of bone remodeling GO:0046850 143 57 1,000 0,02958291 0,07994584 ! muscle fiber development GO:0048747 131 57 1,000 0,02958291 0,0798575 ! nucleotide-excision repair GO:0006289 91 57 1,000 0,02958291 0,07976936 ! cellular polysaccharide metabolic process GO:0044264 93 58 1,000 0,03054656 0,08227702 ! regulation of tissue remodeling GO:0034103 146 58 1,000 0,03054656 0,08218641 ! positive regulation of organelle organization GO:0010638 108 58 1,000 0,03054656 0,08209599 ! establishment of organelle localization GO:0051656 122 59 1,000 0,03152257 0,08462598 ! tRNA transcription GO:0009304 17 7 0,000 0,03243155 0,08697067 ! positive regulation of MHC class II biosynthetic process GO:0045348 13 7 0,000 0,03243155 0,08687531 GO:0045346|regulation of MHC class II biosynthetic process, ! behavioral response to cocaine GO:0048148 14 7 0,000 0,03243155 0,08678015 ! cytokinesis during cell cycle GO:0033205 14 7 0,000 0,03243155 0,08668521 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 13 7 0,000 0,03243155 0,08659047 ! sleep GO:0030431 16 7 0,000 0,03243155 0,08649594 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,03243155 0,08640161 ! chaperone mediated protein folding requiring cofactor GO:0051085 12 7 0,000 0,03243155 0,08630749 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,03243155 0,08621358 ! prostate gland development GO:0030850 14 7 0,000 0,03243155 0,08611987 ! nucleotide-sugar transport GO:0015780 11 7 0,000 0,03243155 0,08602636 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03243155 0,08593306 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,03243155 0,08583996 ! regulation of lipid catabolic process GO:0050994 17 7 0,000 0,03243155 0,08574706 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03243155 0,08565436 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! platelet activating factor metabolic process GO:0046469 12 7 0,000 0,03243155 0,08556186 ! N-acetylglucosamine catabolic process GO:0006046 10 7 0,000 0,03243155 0,08546956 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,03243155 0,08537746 ! SMAD protein complex assembly GO:0007183 13 7 0,000 0,03243155 0,08528555 ! glycolipid transport GO:0046836 11 7 0,000 0,03243155 0,08519385 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,03243155 0,08510234 GO:0051923|sulfation, ! neuron adhesion GO:0007158 14 7 0,000 0,03243155 0,08501103 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,03243155 0,08491991 ! establishment of tissue polarity GO:0007164 8 7 0,000 0,03243155 0,08482899 ! nucleotide-excision repair, DNA incision GO:0033683 11 7 0,000 0,03243155 0,08473827 ! pericardium development GO:0060039 16 7 0,000 0,03243155 0,08464773 ! glucocorticoid receptor signaling pathway GO:0042921 16 7 0,000 0,03243155 0,0845574 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 17 7 0,000 0,03243155 0,08446725 ! oxaloacetate metabolic process GO:0006107 13 7 0,000 0,03243155 0,08437729 ! regulation of gluconeogenesis GO:0006111 8 7 0,000 0,03243155 0,08428753 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,03243155 0,08419796 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,03243155 0,08410858 ! lipoprotein transport GO:0042953 14 7 0,000 0,03243155 0,08401938 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 10 7 0,000 0,03243155 0,08393038 ! rhythmic behavior GO:0007622 17 7 0,000 0,03243155 0,08384157 ! regulation of dopamine metabolic process GO:0042053 12 7 0,000 0,03243155 0,08375294 GO:0042069|regulation of catecholamine metabolic process, ! neuron remodeling GO:0016322 16 7 0,000 0,03243155 0,0836645 ! sensory perception of temperature stimulus GO:0050951 12 7 0,000 0,03243155 0,08357624 ! glucocorticoid metabolic process GO:0008211 11 7 0,000 0,03243155 0,08348818 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,03243155 0,08340029 ! regulation of odontogenesis GO:0042481 14 7 0,000 0,03243155 0,0833126 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,03243155 0,08322508 ! amyloid precursor protein catabolic process GO:0042987 15 7 0,000 0,03243155 0,08313775 ! mechanosensory behavior GO:0007638 16 7 0,000 0,03243155 0,08305061 ! DNA ligation during DNA repair GO:0051103 12 7 0,000 0,03243155 0,08296364 ! positive regulation of isotype switching GO:0045830 17 7 0,000 0,03243155 0,08287686 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 11 7 0,000 0,03243155 0,08279026 ! negative regulation of viral genome replication GO:0045071 9 7 0,000 0,03243155 0,08270384 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03243155 0,0826176 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03243155 0,08253154 ! spinal cord patterning GO:0021511 14 7 0,000 0,03243155 0,08244566 ! dermatan sulfate proteoglycan metabolic process GO:0050655 16 7 0,000 0,03243155 0,08235996 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 13 7 0,000 0,03243155 0,08227443 ! adrenal gland development GO:0030325 17 7 0,000 0,03243155 0,08218909 ! cysteine metabolic process GO:0006534 13 7 0,000 0,03243155 0,08210392 ! induction of apoptosis by oxidative stress GO:0008631 9 7 0,000 0,03243155 0,08201892 ! ovulation GO:0030728 10 7 0,000 0,03243155 0,08193411 ! adenohypophysis development GO:0021984 11 7 0,000 0,03243155 0,08184946 ! deoxyribonucleotide biosynthetic process GO:0009263 13 7 0,000 0,03243155 0,08176499 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 12 7 0,000 0,03243155 0,0816807 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 21 7 0,000 0,03243155 0,08159658 ! microtubule nucleation GO:0007020 21 7 0,000 0,03243155 0,08151263 ! proline biosynthetic process GO:0006561 10 7 0,000 0,03243155 0,08142886 ! tryptophan metabolic process GO:0006568 11 7 0,000 0,03243155 0,08134526 ! thyroid hormone generation GO:0006590 13 7 0,000 0,03243155 0,08126183 ! regulation of granule cell precursor proliferation GO:0021936 12 7 0,000 0,03243155 0,08117857 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 13 7 0,000 0,03243155 0,08109548 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03243155 0,08101256 ! peptidoglycan metabolic process GO:0000270 7 7 0,000 0,03243155 0,08092981 GO:0009253|peptidoglycan catabolic process, ! positive regulation of activated T cell proliferation GO:0042104 15 7 0,000 0,03243155 0,08084722 ! galactose metabolic process GO:0006012 13 7 0,000 0,03243155 0,08076481 ! vesicle fusion GO:0006906 20 7 0,000 0,03243155 0,08068257 ! response to dietary excess GO:0002021 8 7 0,000 0,03243155 0,08060049 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,03243155 0,08051858 ! intracellular pH reduction GO:0051452 13 7 0,000 0,03243155 0,08043683 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,03243155 0,08035525 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 10 7 0,000 0,03243155 0,08027384 ! organ growth GO:0035265 15 7 0,000 0,03243155 0,08019259 ! nucleoside transport GO:0015858 11 7 0,000 0,03243155 0,08011151 ! nucleoside salvage GO:0043174 11 7 0,000 0,03243155 0,08003059 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 16 7 0,000 0,03243155 0,07994983 ! antigen processing and presentation of endogenous peptide antigen GO:0002483 17 7 0,000 0,03243155 0,07986923 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! negative regulation of DNA recombination GO:0045910 16 7 0,000 0,03243155 0,0797888 ! parturition GO:0007567 16 7 0,000 0,03243155 0,07970853 ! positive regulation of mitotic cell cycle GO:0045931 14 7 0,000 0,03243155 0,07962842 ! rRNA modification GO:0000154 14 7 0,000 0,03243155 0,07954847 ! regulation of chromatin assembly or disassembly GO:0001672 14 7 0,000 0,03243155 0,07946869 ! spindle checkpoint GO:0031577 16 7 0,000 0,03243155 0,07938906 ! wound healing, spreading of epidermal cells GO:0035313 16 7 0,000 0,03243155 0,07930959 ! regulation of cholesterol biosynthetic process GO:0045540 14 7 0,000 0,03243155 0,07923028 ! monocyte differentiation GO:0030224 16 7 0,000 0,03243155 0,07915113 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 15 7 0,000 0,03243155 0,07907214 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,03243155 0,0789933 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 14 7 0,000 0,03243155 0,07891462 ! hyaluronan metabolic process GO:0030212 9 7 0,000 0,03243155 0,0788361 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,03243155 0,07875773 ! fibrinolysis GO:0042730 11 7 0,000 0,03243155 0,07867952 ! skeletal muscle contraction GO:0003009 8 7 0,000 0,03243155 0,07860147 ! eating behavior GO:0042755 8 7 0,000 0,03243155 0,07852357 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,03243155 0,07844582 ! positive regulation of systemic arterial blood pressure GO:0003084 11 7 0,000 0,03243155 0,07836823 ! negative regulation of interferon-gamma production GO:0032689 13 7 0,000 0,03243155 0,07829079 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,03243155 0,0782135 ! negative regulation of focal adhesion formation GO:0051895 21 7 0,000 0,03243155 0,07813637 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,03243155 0,07805939 ! cranial nerve morphogenesis GO:0021602 12 7 0,000 0,03243155 0,07798256 ! phosphatidylinositol biosynthetic process GO:0006661 19 7 0,000 0,03243155 0,07790588 ! purine deoxyribonucleotide metabolic process GO:0009151 8 7 0,000 0,03243155 0,07782935 ! regulation of interleukin-1 beta production GO:0032651 11 7 0,000 0,03243155 0,07775297 ! positive regulation of tumor necrosis factor production GO:0032760 10 7 0,000 0,03243155 0,07767674 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,03243155 0,07760067 ! histone ubiquitination GO:0016574 9 7 0,000 0,03243155 0,07752474 ! regulation of meiosis GO:0040020 12 7 0,000 0,03243155 0,07744895 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 14 7 0,000 0,03243155 0,07737332 ! positive regulation of immunoglobulin mediated immune response GO:0002891 16 7 0,000 0,03243155 0,07729783 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,03243155 0,07722249 ! membrane to membrane docking GO:0022614 14 7 0,000 0,03243155 0,0771473 ! transcription termination GO:0006353 14 7 0,000 0,03243155 0,07707226 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,03243155 0,07699736 ! anaphase GO:0051322 18 7 0,000 0,03243155 0,0769226 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 17 7 0,000 0,03243155 0,07684799 ! negative regulation of nuclear division GO:0051784 15 7 0,000 0,03243155 0,07677353 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 16 7 0,000 0,03243155 0,07669921 ! energy coupled proton transport, against electrochemical gradient GO:0015988 13 7 0,000 0,03243155 0,07662503 GO:0015991|ATP hydrolysis coupled proton transport, ! peptidyl-threonine modification GO:0018210 26 7 0,000 0,03243155 0,07655099 ! diuresis GO:0030146 12 7 0,000 0,03243155 0,0764771 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,03243155 0,07640336 ! thiamin metabolic process GO:0006772 7 7 0,000 0,03243155 0,07632975 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03243155 0,07625628 ! antibiotic transport GO:0042891 9 7 0,000 0,03243155 0,07618296 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,03243155 0,07610978 ! tetrahydrobiopterin biosynthetic process GO:0006729 9 7 0,000 0,03243155 0,07603674 ! positive regulation of T-helper 2 cell differentiation GO:0045630 13 7 0,000 0,03243155 0,07596383 ! regulation of T-helper 1 cell differentiation GO:0045625 10 7 0,000 0,03243155 0,07589107 ! negative regulation of transmission of nerve impulse GO:0051970 15 7 0,000 0,03243155 0,07581845 ! melanin biosynthetic process GO:0042438 10 7 0,000 0,03243155 0,07574597 ! aspartate family amino acid catabolic process GO:0009068 10 7 0,000 0,03243155 0,07567362 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,03243155 0,07560141 ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,03243155 0,07552934 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 13 7 0,000 0,03243155 0,07545741 ! nonprotein amino acid metabolic process GO:0019794 15 7 0,000 0,03243155 0,07538561 ! regulation of T cell mediated cytotoxicity GO:0001914 19 7 0,000 0,03243155 0,07531395 ! endosome to lysosome transport GO:0008333 12 7 0,000 0,03243155 0,07524243 ! protein modification by small protein removal GO:0070646 19 7 0,000 0,03243155 0,07517104 ! lymphocyte activation during immune response GO:0002285 11 7 0,000 0,03243155 0,07509979 ! positive regulation of fibrinolysis GO:0051919 12 7 0,000 0,03243155 0,07502867 ! negative regulation of telomere maintenance GO:0032205 13 7 0,000 0,03243155 0,07495769 ! toll-like receptor signaling pathway GO:0002224 10 7 0,000 0,03243155 0,07488684 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,03243155 0,07481613 ! muscle adaptation GO:0043500 13 7 0,000 0,03243155 0,07474555 ! embryonic heart tube development GO:0035050 14 7 0,000 0,03243155 0,0746751 ! retina homeostasis GO:0001895 12 7 0,000 0,03243155 0,07460478 ! negative regulation of nucleotide metabolic process GO:0045980 13 7 0,000 0,03243155 0,0745346 ! protein amino acid prenylation GO:0018346 19 7 0,000 0,03243155 0,07446455 ! positive regulation of microtubule polymerization GO:0031116 15 7 0,000 0,03243155 0,07439463 ! defense response to Gram-negative bacterium GO:0050829 10 7 0,000 0,03243155 0,07432484 ! kidney development GO:0001822 133 60 1,000 0,03251079 0,0744366 ! camera-type eye development GO:0043010 126 61 1,000 0,03351108 0,07665502 ! viral reproductive process GO:0022415 132 62 1,000 0,03452331 0,07889659 ! DNA damage response, signal transduction GO:0042770 136 62 1,000 0,03452331 0,07882285 ! regulation of mitosis GO:0007088 112 63 1,000 0,03554736 0,08108515 GO:0051783|regulation of nuclear division, ! skeletal system morphogenesis GO:0048705 118 63 1,000 0,03554736 0,08100951 ! integrin-mediated signaling pathway GO:0007229 160 64 1,000 0,03658308 0,08329214 ! response to peptide hormone stimulus GO:0043434 129 64 1,000 0,03658308 0,08321459 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 17 8 0,000 0,03697847 0,08403573 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 18 8 0,000 0,03697847 0,08395763 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 18 8 0,000 0,03697847 0,08387967 ! somatic diversification of immune receptors via somatic mutation GO:0002566 12 8 0,000 0,03697847 0,08380186 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 17 8 0,000 0,03697847 0,0837242 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,03697847 0,08364667 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,03697847 0,08356929 ! glycerol-3-phosphate metabolic process GO:0006072 15 8 0,000 0,03697847 0,08349206 ! neutral lipid biosynthetic process GO:0046460 12 8 0,000 0,03697847 0,08341497 GO:0046463|acylglycerol biosynthetic process, ! regulation of cellular amine metabolic process GO:0033238 13 8 0,000 0,03697847 0,08333801 ! meiotic prophase I GO:0007128 14 8 0,000 0,03697847 0,08326121 ! response to zinc ion GO:0010043 12 8 0,000 0,03697847 0,08318454 ! regulation of lipid kinase activity GO:0043550 17 8 0,000 0,03697847 0,08310801 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,03697847 0,08303162 ! oligopeptide transport GO:0006857 16 8 0,000 0,03697847 0,08295538 ! actin-myosin filament sliding GO:0033275 13 8 0,000 0,03697847 0,08287927 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! protein thiol-disulfide exchange GO:0006467 10 8 0,000 0,03697847 0,08280331 ! receptor guanylyl cyclase signaling pathway GO:0007168 10 8 0,000 0,03697847 0,08272748 ! signal peptide processing GO:0006465 12 8 0,000 0,03697847 0,08265179 ! prostaglandin biosynthetic process GO:0001516 15 8 0,000 0,03697847 0,08257624 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 18 8 0,000 0,03697847 0,08250083 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,03697847 0,08242555 ! succinate metabolic process GO:0006105 17 8 0,000 0,03697847 0,08235042 ! tachykinin receptor signaling pathway GO:0007217 12 8 0,000 0,03697847 0,08227542 ! membrane hyperpolarization GO:0060081 11 8 0,000 0,03697847 0,08220055 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,03697847 0,08212583 ! estrogen metabolic process GO:0008210 17 8 0,000 0,03697847 0,08205123 ! negative regulation of muscle cell differentiation GO:0051148 17 8 0,000 0,03697847 0,08197678 ! regulation of response to extracellular stimulus GO:0032104 14 8 0,000 0,03697847 0,08190245 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,03697847 0,08182827 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,03697847 0,08175422 ! reflex GO:0060004 17 8 0,000 0,03697847 0,0816803 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,03697847 0,08160651 ! glycerolipid catabolic process GO:0046503 14 8 0,000 0,03697847 0,08153286 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,03697847 0,08145934 ! pigment granule organization GO:0048753 17 8 0,000 0,03697847 0,08138595 ! regulation of defense response to virus by host GO:0050691 9 8 0,000 0,03697847 0,0813127 ! regulation of defense response to virus by virus GO:0050690 22 8 0,000 0,03697847 0,08123958 ! astrocyte differentiation GO:0048708 19 8 0,000 0,03697847 0,08116658 ! histidine catabolic process GO:0006548 10 8 0,000 0,03697847 0,08109372 GO:0009077|histidine family amino acid catabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,03697847 0,08102099 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 15 8 0,000 0,03697847 0,08094839 ! regulation of interleukin-6 biosynthetic process GO:0045408 13 8 0,000 0,03697847 0,08087592 ! regulation of pigmentation during development GO:0048070 25 8 0,000 0,03697847 0,08080358 ! melanin metabolic process GO:0006582 17 8 0,000 0,03697847 0,08073137 ! tetrahydrobiopterin metabolic process GO:0046146 11 8 0,000 0,03697847 0,08065929 ! embryonic eye morphogenesis GO:0048048 16 8 0,000 0,03697847 0,08058734 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 13 8 0,000 0,03697847 0,08051551 ! macrophage activation GO:0042116 13 8 0,000 0,03697847 0,08044382 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,03697847 0,08037225 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! positive regulation of insulin secretion GO:0032024 17 8 0,000 0,03697847 0,08030081 ! cerebral cortex neuron differentiation GO:0021895 16 8 0,000 0,03697847 0,08022949 ! purine salvage GO:0043101 12 8 0,000 0,03697847 0,0801583 ! regulation of multicellular organismal metabolic process GO:0044246 12 8 0,000 0,03697847 0,08008724 ! osteoblast development GO:0002076 17 8 0,000 0,03697847 0,0800163 ! positive regulation of vasodilation GO:0045909 14 8 0,000 0,03697847 0,07994549 ! negative regulation of translational initiation GO:0045947 12 8 0,000 0,03697847 0,07987481 ! Schwann cell differentiation GO:0014037 21 8 0,000 0,03697847 0,07980425 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 23 8 0,000 0,03697847 0,07973381 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,03697847 0,0796635 ! response to UV-B GO:0010224 17 8 0,000 0,03697847 0,07959331 ! protein targeting to vacuole GO:0006623 14 8 0,000 0,03697847 0,07952325 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,03697847 0,0794533 ! intermediate filament organization GO:0045109 12 8 0,000 0,03697847 0,07938349 ! cardiac muscle cell differentiation GO:0055007 31 8 0,000 0,03697847 0,07931379 ! cellular extravasation GO:0045123 13 8 0,000 0,03697847 0,07924422 ! cardiac muscle cell development GO:0055013 14 8 0,000 0,03697847 0,07917477 ! response to antibiotic GO:0046677 11 8 0,000 0,03697847 0,07910544 ! transcription-coupled nucleotide-excision repair GO:0006283 14 8 0,000 0,03697847 0,07903623 ! positive regulation of production of molecular mediator of immune response GO:0002702 31 8 0,000 0,03697847 0,07896714 ! DNA topological change GO:0006265 12 8 0,000 0,03697847 0,07889817 ! response to tropane GO:0014073 15 8 0,000 0,03697847 0,07882933 GO:0042220|response to cocaine, ! melanosome transport GO:0032402 13 8 0,000 0,03697847 0,0787606 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,03697847 0,07869199 ! mast cell activation GO:0045576 14 8 0,000 0,03697847 0,07862351 ! multicellular organismal aging GO:0010259 20 8 0,000 0,03697847 0,07855514 ! regulation of focal adhesion formation GO:0051893 23 8 0,000 0,03697847 0,07848689 ! dendrite morphogenesis GO:0048813 14 8 0,000 0,03697847 0,07841876 ! phosphatidylserine metabolic process GO:0006658 9 8 0,000 0,03697847 0,07835074 ! regulation of interleukin-1 production GO:0032652 14 8 0,000 0,03697847 0,07828285 ! nucleosome disassembly GO:0006337 14 8 0,000 0,03697847 0,07821507 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,03697847 0,07814741 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! establishment of nucleus localization GO:0040023 18 8 0,000 0,03697847 0,07807987 ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,03697847 0,07801244 ! establishment of chromosome localization GO:0051303 14 8 0,000 0,03697847 0,07794513 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 15 8 0,000 0,03697847 0,07787794 ! intracellular lipid transport GO:0032365 16 8 0,000 0,03697847 0,07781086 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,03697847 0,0777439 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 17 8 0,000 0,03697847 0,07767705 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,03697847 0,07761032 ! positive regulation of leukocyte chemotaxis GO:0002690 18 8 0,000 0,03697847 0,0775437 GO:0002688|regulation of leukocyte chemotaxis, ! regulation of synaptic transmission, glutamatergic GO:0051966 18 8 0,000 0,03697847 0,07747719 ! hormone catabolic process GO:0042447 17 8 0,000 0,03697847 0,0774108 ! glycolipid catabolic process GO:0019377 16 8 0,000 0,03697847 0,07734453 GO:0046479|glycosphingolipid catabolic process, ! lymph node development GO:0048535 11 8 0,000 0,03697847 0,07727836 ! positive regulation of ATPase activity GO:0032781 13 8 0,000 0,03697847 0,07721231 ! negative regulation of viral reproduction GO:0048525 10 8 0,000 0,03697847 0,07714638 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,03697847 0,07708055 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 15 8 0,000 0,03697847 0,07701484 ! adult feeding behavior GO:0008343 10 8 0,000 0,03697847 0,07694924 ! regulation of Rac protein signal transduction GO:0035020 18 8 0,000 0,03697847 0,07688375 ! ATP catabolic process GO:0006200 11 8 0,000 0,03697847 0,07681837 ! blastocyst growth GO:0001832 19 8 0,000 0,03697847 0,07675311 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,03697847 0,07668795 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,03697847 0,07662291 ! pattern recognition receptor signaling pathway GO:0002221 13 8 0,000 0,03697847 0,07655797 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,03697847 0,07649315 ! regulation of synaptic transmission, GABAergic GO:0032228 17 8 0,000 0,03697847 0,07642843 ! negative regulation of blood vessel endothelial cell migration GO:0043537 22 8 0,000 0,03697847 0,07636383 ! positive regulation of NF-kappaB import into nucleus GO:0042346 15 8 0,000 0,03697847 0,07629933 ! pyrimidine nucleotide catabolic process GO:0006244 16 8 0,000 0,03697847 0,07623494 ! amino sugar catabolic process GO:0046348 11 8 0,000 0,03697847 0,07617066 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 22 8 0,000 0,03697847 0,07610649 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,03697847 0,07604243 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 18 8 0,000 0,03697847 0,07597848 ! positive regulation of smooth muscle contraction GO:0045987 15 8 0,000 0,03697847 0,07591463 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,03697847 0,07585089 ! negative regulation of DNA replication initiation GO:0032297 10 8 0,000 0,03697847 0,07578725 GO:0000076|DNA replication checkpoint, ! protein prenylation GO:0018342 21 8 0,000 0,03697847 0,07572373 ! NAD biosynthetic process GO:0009435 17 8 0,000 0,03697847 0,07566031 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 17 8 0,000 0,03697847 0,07559699 ! regulation of microtubule polymerization GO:0031113 17 8 0,000 0,03697847 0,07553379 ! regulation of cytokine biosynthetic process GO:0042035 108 66 1,000 0,03868904 0,07896184 ! gonad development GO:0008406 115 66 1,000 0,03868904 0,07889592 ! activation of MAPK activity GO:0000187 124 67 1,000 0,03975901 0,08101023 ! chromosome segregation GO:0007059 127 67 1,000 0,03975901 0,08094272 ! myeloid cell differentiation GO:0030099 126 67 1,000 0,03975901 0,08087532 ! negative regulation of ligase activity GO:0051352 116 68 1,000 0,04084015 0,08300539 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! viral reproduction GO:0016032 142 68 1,000 0,04084015 0,08293639 ! adaptive immune response GO:0002250 126 68 1,000 0,04084015 0,08286751 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 114 68 1,000 0,04084015 0,08279874 ! cell projection assembly GO:0030031 138 68 1,000 0,04084015 0,08273008 ! axon extension GO:0048675 16 9 0,000 0,04150415 0,08400551 ! 'de novo' posttranslational protein folding GO:0051084 15 9 0,000 0,04150415 0,08393597 ! regulation of epithelial cell differentiation GO:0030856 18 9 0,000 0,04150415 0,08386654 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,04150415 0,08379723 GO:0006740|NADPH regeneration, ! DNA synthesis during DNA repair GO:0000731 18 9 0,000 0,04150415 0,08372803 ! cell proliferation in forebrain GO:0021846 18 9 0,000 0,04150415 0,08365895 ! neutral lipid catabolic process GO:0046461 14 9 0,000 0,04150415 0,08358998 ! reproductive behavior GO:0019098 22 9 0,000 0,04150415 0,08352113 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,04150415 0,08345238 ! regulation of epidermal growth factor receptor activity GO:0007176 17 9 0,000 0,04150415 0,08338375 GO:0010469|regulation of receptor activity, ! Golgi to endosome transport GO:0006895 25 9 0,000 0,04150415 0,08331524 ! UTP metabolic process GO:0046051 10 9 0,000 0,04150415 0,08324684 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! RNA methylation GO:0001510 16 9 0,000 0,04150415 0,08317854 ! regulation of activated T cell proliferation GO:0046006 19 9 0,000 0,04150415 0,08311037 ! artery development GO:0060840 25 9 0,000 0,04150415 0,0830423 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 14 9 0,000 0,04150415 0,08297434 ! cerebral cortex cell migration GO:0021795 18 9 0,000 0,04150415 0,0829065 ! equilibrioception GO:0050957 20 9 0,000 0,04150415 0,08283876 ! cytoplasmic sequestering of transcription factor GO:0042994 15 9 0,000 0,04150415 0,08277114 ! chemosensory behavior GO:0007635 21 9 0,000 0,04150415 0,08270363 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,04150415 0,08263622 ! amyloid precursor protein metabolic process GO:0042982 18 9 0,000 0,04150415 0,08256893 ! leukocyte degranulation GO:0043299 16 9 0,000 0,04150415 0,08250175 ! ganglioside metabolic process GO:0001573 22 9 0,000 0,04150415 0,08243467 ! negative regulation of endocytosis GO:0045806 12 9 0,000 0,04150415 0,08236771 ! positive regulation of gene expression, epigenetic GO:0045815 22 9 0,000 0,04150415 0,08230085 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 16 9 0,000 0,04150415 0,0822341 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,04150415 0,08216746 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,04150415 0,08210093 ! glycerol ether biosynthetic process GO:0046504 14 9 0,000 0,04150415 0,0820345 ! protein targeting to ER GO:0045047 25 9 0,000 0,04150415 0,08196819 ! ceramide biosynthetic process GO:0046513 20 9 0,000 0,04150415 0,08190198 ! nerve growth factor receptor signaling pathway GO:0048011 20 9 0,000 0,04150415 0,08183587 ! T cell selection GO:0045058 27 9 0,000 0,04150415 0,08176988 ! insulin-like growth factor receptor signaling pathway GO:0048009 22 9 0,000 0,04150415 0,08170399 ! embryonic cranial skeleton morphogenesis GO:0048701 20 9 0,000 0,04150415 0,0816382 ! glycine catabolic process GO:0006546 15 9 0,000 0,04150415 0,08157252 ! cytoskeletal anchoring at plasma membrane GO:0007016 31 9 0,000 0,04150415 0,08150695 ! endosome organization GO:0007032 20 9 0,000 0,04150415 0,08144148 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,04150415 0,08137612 ! retinoic acid receptor signaling pathway GO:0048384 16 9 0,000 0,04150415 0,08131086 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,04150415 0,08124571 ! mannose metabolic process GO:0006013 13 9 0,000 0,04150415 0,08118066 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 25 9 0,000 0,04150415 0,08111572 ! retrograde transport, endosome to Golgi GO:0042147 29 9 0,000 0,04150415 0,08105088 ! positive regulation of mesenchymal cell proliferation GO:0002053 34 9 0,000 0,04150415 0,08098614 ! Rac protein signal transduction GO:0016601 20 9 0,000 0,04150415 0,08092151 ! receptor clustering GO:0043113 20 9 0,000 0,04150415 0,08085697 ! neurotransmitter catabolic process GO:0042135 18 9 0,000 0,04150415 0,08079255 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,04150415 0,08072822 ! retinol metabolic process GO:0042572 20 9 0,000 0,04150415 0,080664 ! negative regulation of muscle contraction GO:0045932 16 9 0,000 0,04150415 0,08059988 ! determination of anterior/posterior axis, embryo GO:0008595 17 9 0,000 0,04150415 0,08053586 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 24 9 0,000 0,04150415 0,08047194 ! macrophage differentiation GO:0030225 15 9 0,000 0,04150415 0,08040813 ! oligodendrocyte development GO:0014003 11 9 0,000 0,04150415 0,08034441 ! positive regulation of myeloid leukocyte differentiation GO:0002763 25 9 0,000 0,04150415 0,0802808 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,04150415 0,08021728 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! regulation of circadian rhythm GO:0042752 20 9 0,000 0,04150415 0,08015387 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,04150415 0,08009056 ! response to amine stimulus GO:0014075 13 9 0,000 0,04150415 0,08002734 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,04150415 0,07996423 ! nucleoside diphosphate metabolic process GO:0009132 17 9 0,000 0,04150415 0,07990122 ! erythrocyte development GO:0048821 17 9 0,000 0,04150415 0,0798383 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,04150415 0,07977549 ! regulation of mitochondrial membrane potential GO:0051881 19 9 0,000 0,04150415 0,07971277 ! renal water homeostasis GO:0003091 15 9 0,000 0,04150415 0,07965015 ! postreplication repair GO:0006301 25 9 0,000 0,04150415 0,07958763 ! protein import into peroxisome matrix GO:0016558 20 9 0,000 0,04150415 0,07952521 ! icosanoid secretion GO:0032309 15 9 0,000 0,04150415 0,07946289 GO:0050482|arachidonic acid secretion, ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,04150415 0,07940066 GO:0021696|cerebellar cortex morphogenesis, ! regulation of cell division GO:0051302 17 9 0,000 0,04150415 0,07933853 ! retinal ganglion cell axon guidance GO:0031290 14 9 0,000 0,04150415 0,0792765 ! morphogenesis of a polarized epithelium GO:0001738 12 9 0,000 0,04150415 0,07921457 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,04150415 0,07915273 ! sterol catabolic process GO:0016127 14 9 0,000 0,04150415 0,07909099 GO:0006707|cholesterol catabolic process, ! negative regulation of cytokine secretion GO:0050710 16 9 0,000 0,04150415 0,07902934 ! regulation of T-helper 1 type immune response GO:0002825 12 9 0,000 0,04150415 0,07896779 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 9 0,000 0,04150415 0,07890634 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 10 9 0,000 0,04150415 0,07884498 GO:0000084|S phase of mitotic cell cycle, ! regulation of macrophage activation GO:0043030 17 9 0,000 0,04150415 0,07878372 ! regulation of macrophage differentiation GO:0045649 16 9 0,000 0,04150415 0,07872255 ! neuromuscular process controlling posture GO:0050884 15 9 0,000 0,04150415 0,07866148 ! negative regulation of lymphocyte differentiation GO:0045620 20 9 0,000 0,04150415 0,0786005 ! branched chain family amino acid catabolic process GO:0009083 19 9 0,000 0,04150415 0,07853962 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,04150415 0,07847883 ! purine base metabolic process GO:0006144 25 9 0,000 0,04150415 0,07841813 ! pigment granule transport GO:0051904 17 9 0,000 0,04150415 0,07835753 ! regulation of telomere maintenance GO:0032204 17 9 0,000 0,04150415 0,07829702 ! pyrimidine base metabolic process GO:0006206 22 9 0,000 0,04150415 0,07823661 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 10 9 0,000 0,04150415 0,07817629 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,04150415 0,07811606 ! regulation of amino acid transport GO:0051955 12 9 0,000 0,04150415 0,07805592 ! mitochondrion localization GO:0051646 18 9 0,000 0,04150415 0,07799588 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 116 69 1,000 0,04193231 0,07873992 ! urogenital system development GO:0001655 149 69 1,000 0,04193231 0,07867945 ! cellular amino acid catabolic process GO:0009063 120 69 1,000 0,04193231 0,07861906 ! single fertilization GO:0007338 83 69 1,000 0,04193231 0,07855877 ! cell redox homeostasis GO:0045454 114 70 1,000 0,04303539 0,08056356 ! germ cell development GO:0007281 133 70 1,000 0,04303539 0,08050188 ! B cell activation GO:0042113 179 72 1,000 0,04527376 0,08462417 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 119 72 1,000 0,04527376 0,08455947 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 123 72 1,000 0,04527376 0,08449487 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 22 10 0,000 0,04600869 0,08580094 ! autophagic vacuole formation GO:0000045 17 10 0,000 0,04600869 0,0857355 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,04600869 0,08567015 ! negative regulation of lipid biosynthetic process GO:0051055 15 10 0,000 0,04600869 0,0856049 ! associative learning GO:0008306 21 10 0,000 0,04600869 0,08553975 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,04600869 0,0854747 ! phosphate transport GO:0006817 24 10 0,000 0,04600869 0,08540975 ! cell volume homeostasis GO:0006884 17 10 0,000 0,04600869 0,0853449 ! CTP metabolic process GO:0046036 11 10 0,000 0,04600869 0,08528015 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! SMAD protein nuclear translocation GO:0007184 21 10 0,000 0,04600869 0,08521549 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,04600869 0,08515094 ! GTP metabolic process GO:0046039 11 10 0,000 0,04600869 0,08508648 ! syncytium formation by plasma membrane fusion GO:0000768 18 10 0,000 0,04600869 0,08502211 GO:0007520|myoblast fusion, ! elastic fiber assembly GO:0048251 17 10 0,000 0,04600869 0,08495785 ! social behavior GO:0035176 29 10 0,000 0,04600869 0,08489368 ! COPI coating of Golgi vesicle GO:0048205 23 10 0,000 0,04600869 0,08482961 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 18 10 0,000 0,04600869 0,08476564 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 22 10 0,000 0,04600869 0,08470176 ! androgen metabolic process GO:0008209 17 10 0,000 0,04600869 0,08463798 ! phospholipid efflux GO:0033700 19 10 0,000 0,04600869 0,08457429 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,04600869 0,0845107 ! bile acid and bile salt transport GO:0015721 15 10 0,000 0,04600869 0,08444721 ! regulation of mesenchymal cell proliferation GO:0010464 36 10 0,000 0,04600869 0,08438381 ! positive regulation of heart contraction GO:0045823 17 10 0,000 0,04600869 0,08432051 ! pathogenesis GO:0009405 17 10 0,000 0,04600869 0,0842573 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,04600869 0,08419418 ! sphingoid biosynthetic process GO:0046520 22 10 0,000 0,04600869 0,08413116 ! regulation of S phase of mitotic cell cycle GO:0007090 18 10 0,000 0,04600869 0,08406824 ! endoderm development GO:0007492 18 10 0,000 0,04600869 0,08400541 ! positive regulation of survival gene product expression GO:0045885 26 10 0,000 0,04600869 0,08394267 ! arginine catabolic process GO:0006527 17 10 0,000 0,04600869 0,08388003 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,04600869 0,08381748 ! proline metabolic process GO:0006560 13 10 0,000 0,04600869 0,08375502 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,04600869 0,08369265 GO:0005978|glycogen biosynthetic process, ! phosphagen metabolic process GO:0006599 17 10 0,000 0,04600869 0,08363038 GO:0006600|creatine metabolic process, ! polyamine biosynthetic process GO:0006596 13 10 0,000 0,04600869 0,0835682 ! V(D)J recombination GO:0033151 34 10 0,000 0,04600869 0,08350612 ! reverse cholesterol transport GO:0043691 19 10 0,000 0,04600869 0,08344412 ! central nervous system neuron axonogenesis GO:0021955 23 10 0,000 0,04600869 0,08338222 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 34 10 0,000 0,04600869 0,08332041 ! B cell proliferation GO:0042100 19 10 0,000 0,04600869 0,08325869 ! nucleobase biosynthetic process GO:0046112 26 10 0,000 0,04600869 0,08319707 ! regulation of sodium ion transport GO:0002028 26 10 0,000 0,04600869 0,08313553 ! multicellular organism growth GO:0035264 19 10 0,000 0,04600869 0,08307408 ! phagocytosis, engulfment GO:0006911 33 10 0,000 0,04600869 0,08301273 ! neurotransmitter biosynthetic process GO:0042136 18 10 0,000 0,04600869 0,08295147 ! ruffle organization GO:0031529 17 10 0,000 0,04600869 0,08289029 ! epithelial cell development GO:0002064 21 10 0,000 0,04600869 0,08282921 ! lens development in camera-type eye GO:0002088 17 10 0,000 0,04600869 0,08276821 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,04600869 0,08270731 ! intestinal cholesterol absorption GO:0030299 19 10 0,000 0,04600869 0,0826465 ! positive regulation of translational initiation GO:0045948 12 10 0,000 0,04600869 0,08258577 ! chondroitin sulfate biosynthetic process GO:0030206 22 10 0,000 0,04600869 0,08252514 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 13 10 0,000 0,04600869 0,08246459 ! regulation of gliogenesis GO:0014013 23 10 0,000 0,04600869 0,08240413 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 23 10 0,000 0,04600869 0,08234376 ! alpha-beta T cell differentiation GO:0046632 24 10 0,000 0,04600869 0,08228348 ! segment specification GO:0007379 15 10 0,000 0,04600869 0,08222329 ! positive regulation of phagocytosis GO:0050766 14 10 0,000 0,04600869 0,08216318 ! blastoderm segmentation GO:0007350 19 10 0,000 0,04600869 0,08210317 ! base-excision repair, AP site formation GO:0006285 15 10 0,000 0,04600869 0,08204324 ! response to dsRNA GO:0043331 23 10 0,000 0,04600869 0,0819834 ! DNA ligation GO:0006266 18 10 0,000 0,04600869 0,08192364 ! regulation of fat cell differentiation GO:0045598 18 10 0,000 0,04600869 0,08186397 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,04600869 0,08180439 ! melanosome localization GO:0032400 16 10 0,000 0,04600869 0,0817449 ! glycosphingolipid biosynthetic process GO:0006688 16 10 0,000 0,04600869 0,08168549 ! regulation of B cell differentiation GO:0045577 24 10 0,000 0,04600869 0,08162617 ! regulation of protein kinase B signaling cascade GO:0051896 27 10 0,000 0,04600869 0,08156693 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,04600869 0,08150779 ! spinal cord motor neuron differentiation GO:0021522 19 10 0,000 0,04600869 0,08144872 ! leukocyte activation during immune response GO:0002366 15 10 0,000 0,04600869 0,08138974 GO:0002263|cell activation during immune response, ! mRNA cleavage GO:0006379 18 10 0,000 0,04600869 0,08133085 ! protein sumoylation GO:0016925 17 10 0,000 0,04600869 0,08127204 ! synaptic vesicle endocytosis GO:0048488 23 10 0,000 0,04600869 0,08121332 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,04600869 0,08115468 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,04600869 0,08109613 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,04600869 0,08103766 ! positive regulation of interleukin-1 beta secretion GO:0050718 15 10 0,000 0,04600869 0,08097928 ! salivary gland development GO:0007431 28 10 0,000 0,04600869 0,08092098 ! ubiquinone metabolic process GO:0006743 17 10 0,000 0,04600869 0,08086276 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 18 10 0,000 0,04600869 0,08080463 ! musculoskeletal movement GO:0050881 16 10 0,000 0,04600869 0,08074658 GO:0050879|multicellular organismal movement, ! multicellular organismal water homeostasis GO:0050891 16 10 0,000 0,04600869 0,08068861 ! methionine biosynthetic process GO:0009086 21 10 0,000 0,04600869 0,08063073 ! serine family amino acid catabolic process GO:0009071 18 10 0,000 0,04600869 0,08057293 ! nicotinamide nucleotide biosynthetic process GO:0019359 20 10 0,000 0,04600869 0,08051521 ! quaternary ammonium group transport GO:0015697 22 10 0,000 0,04600869 0,08045758 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,04600869 0,08040003 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,04600869 0,08034256 ! positive regulation of viral reproduction GO:0048524 19 10 0,000 0,04600869 0,08028517 ! detection of calcium ion GO:0005513 24 10 0,000 0,04600869 0,08022786 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,04600869 0,08017064 ! blastocyst formation GO:0001825 18 10 0,000 0,04600869 0,0801135 ! regulation of fibrinolysis GO:0051917 20 10 0,000 0,04600869 0,08005644 ! cerebellar cortex development GO:0021695 16 10 0,000 0,04600869 0,07999946 ! natural killer cell mediated immunity GO:0002228 19 10 0,000 0,04600869 0,07994256 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 17 10 0,000 0,04600869 0,07988574 ! response to nicotine GO:0035094 20 10 0,000 0,04600869 0,079829 ! negative regulation of immune effector process GO:0002698 23 10 0,000 0,04600869 0,07977235 ! amino acid transport GO:0006865 148 74 1,000 0,04755426 0,08239366 ! organelle localization GO:0051640 155 74 1,000 0,04755426 0,08233527 ! reproductive structure development GO:0048608 131 75 1,000 0,04871001 0,08427659 ! eye development GO:0001654 155 75 1,000 0,04871001 0,08421695 ! rhythmic process GO:0048511 142 75 1,000 0,04871001 0,08415739 ! cell-matrix adhesion GO:0007160 181 76 1,000 0,04987593 0,08611087 ! respiratory burst GO:0045730 17 11 0,000 0,05049219 0,08711329 ! very-long-chain fatty acid metabolic process GO:0000038 22 11 0,000 0,05049219 0,08705181 ! neuron fate specification GO:0048665 18 11 0,000 0,05049219 0,08699042 ! telencephalon cell migration GO:0022029 23 11 0,000 0,05049219 0,08692912 ! cortical actin cytoskeleton organization GO:0030866 29 11 0,000 0,05049219 0,0868679 ! thyroid gland development GO:0030878 26 11 0,000 0,05049219 0,08680677 ! synapsis GO:0007129 14 11 0,000 0,05049219 0,08674572 GO:0070192|chromosome organization involved in meiosis, ! N-glycan processing GO:0006491 24 11 0,000 0,05049219 0,08668476 ! Golgi vesicle budding GO:0048194 26 11 0,000 0,05049219 0,08662389 ! response to pain GO:0048265 27 11 0,000 0,05049219 0,0865631 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,05049219 0,0865024 ! keratinocyte proliferation GO:0043616 19 11 0,000 0,05049219 0,08644178 ! bone resorption GO:0045453 16 11 0,000 0,05049219 0,08638124 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 15 11 0,000 0,05049219 0,0863208 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,05049219 0,08626043 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,05049219 0,08620015 ! melanocyte differentiation GO:0030318 20 11 0,000 0,05049219 0,08613996 GO:0050931|pigment cell differentiation, ! histidine metabolic process GO:0006547 22 11 0,000 0,05049219 0,08607984 GO:0009075|histidine family amino acid metabolic process, ! syncytium formation GO:0006949 20 11 0,000 0,05049219 0,08601982 ! telomere maintenance via telomerase GO:0007004 24 11 0,000 0,05049219 0,08595987 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 21 11 0,000 0,05049219 0,08590001 ! substrate-bound cell migration GO:0006929 14 11 0,000 0,05049219 0,08584023 ! UV protection GO:0009650 20 11 0,000 0,05049219 0,08578054 ! adult heart development GO:0007512 16 11 0,000 0,05049219 0,08572093 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,05049219 0,0856614 ! macroautophagy GO:0016236 19 11 0,000 0,05049219 0,08560195 ! temperature homeostasis GO:0001659 18 11 0,000 0,05049219 0,08554259 ! behavioral fear response GO:0001662 27 11 0,000 0,05049219 0,08548331 GO:0002209|behavioral defense response, ! positive regulation of muscle contraction GO:0045933 19 11 0,000 0,05049219 0,08542411 ! negative regulation of ossification GO:0030279 27 11 0,000 0,05049219 0,08536499 ! regulation of smoothened signaling pathway GO:0008589 27 11 0,000 0,05049219 0,08530596 ! positive regulation of peptide secretion GO:0002793 24 11 0,000 0,05049219 0,08524701 ! alpha-beta T cell activation GO:0046631 26 11 0,000 0,05049219 0,08518813 ! regulation of organ growth GO:0046620 14 11 0,000 0,05049219 0,08512934 ! pigment granule localization GO:0051875 20 11 0,000 0,05049219 0,08507063 ! positive regulation of T cell mediated immunity GO:0002711 26 11 0,000 0,05049219 0,085012 ! vasoconstriction GO:0042310 20 11 0,000 0,05049219 0,08495345 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 12 11 0,000 0,05049219 0,08489499 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,05049219 0,0848366 ! embryonic axis specification GO:0000578 19 11 0,000 0,05049219 0,08477829 ! sphingomyelin metabolic process GO:0006684 18 11 0,000 0,05049219 0,08472007 ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,05049219 0,08466192 ! positive regulation of Rho GTPase activity GO:0032321 31 11 0,000 0,05049219 0,08460385 ! DNA methylation GO:0006306 19 11 0,000 0,05049219 0,08454586 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 16 11 0,000 0,05049219 0,08448796 ! positive regulation of interleukin-1 secretion GO:0050716 16 11 0,000 0,05049219 0,08443013 ! cellular metabolic compound salvage GO:0043094 16 11 0,000 0,05049219 0,08437238 ! prophase GO:0051324 17 11 0,000 0,05049219 0,08431471 ! neuroblast proliferation GO:0007405 25 11 0,000 0,05049219 0,08425712 ! nucleosome positioning GO:0016584 15 11 0,000 0,05049219 0,0841996 ! regulation of isotype switching GO:0045191 24 11 0,000 0,05049219 0,08414217 ! regulation of interleukin-1 beta secretion GO:0050706 17 11 0,000 0,05049219 0,08408481 ! negative regulation of neurological system process GO:0031645 21 11 0,000 0,05049219 0,08402753 ! apical protein localization GO:0045176 18 11 0,000 0,05049219 0,08397033 ! acid secretion GO:0046717 20 11 0,000 0,05049219 0,08391321 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,05049219 0,08385616 ! positive regulation of neuron differentiation GO:0045666 22 11 0,000 0,05049219 0,0837992 ! nitric oxide mediated signal transduction GO:0007263 26 11 0,000 0,05049219 0,08374231 ! regulation of T-helper 2 cell differentiation GO:0045628 21 11 0,000 0,05049219 0,08368549 ! somatic diversification of immunoglobulins during immune response GO:0002208 23 11 0,000 0,05049219 0,08362876 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 29 11 0,000 0,05049219 0,0835721 ! cholesterol efflux GO:0033344 21 11 0,000 0,05049219 0,08351552 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,05049219 0,08345901 ! oocyte development GO:0048599 20 11 0,000 0,05049219 0,08340258 ! germ cell migration GO:0008354 26 11 0,000 0,05049219 0,08334623 ! embryonic gut development GO:0048566 19 11 0,000 0,05049219 0,08328995 ! regulation of organic acid transport GO:0032890 19 11 0,000 0,05049219 0,08323375 ! establishment or maintenance of apical/basal cell polarity GO:0035088 24 11 0,000 0,05049219 0,08317762 ! activation of innate immune response GO:0002218 16 11 0,000 0,05049219 0,08312157 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 37 11 0,000 0,05049219 0,0830656 ! cardiac cell differentiation GO:0035051 36 11 0,000 0,05049219 0,0830097 ! lysogeny GO:0030069 22 11 0,000 0,05049219 0,08295388 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,05049219 0,08289813 ! T cell receptor signaling pathway GO:0050852 29 11 0,000 0,05049219 0,08284246 ! sequestering of metal ion GO:0051238 15 11 0,000 0,05049219 0,08278686 ! nucleus localization GO:0051647 22 11 0,000 0,05049219 0,08273133 ! amine catabolic process GO:0009310 136 77 1,000 0,05105189 0,08359234 ! positive regulation of ligase activity GO:0051351 130 77 1,000 0,05105189 0,08353635 ! fertilization GO:0009566 99 78 1,000 0,05223779 0,08541962 ! positive regulation of lymphocyte activation GO:0051251 142 78 1,000 0,05223779 0,08536249 ! blood coagulation GO:0007596 151 79 1,000 0,0534335 0,08725804 GO:0050817|coagulation, ! response to steroid hormone stimulus GO:0048545 147 79 1,000 0,0534335 0,08719976 ! regulation of synaptic transmission GO:0050804 159 79 1,000 0,0534335 0,08714154 ! development of primary sexual characteristics GO:0045137 143 80 1,000 0,0546389 0,08904792 ! regulation of membrane protein ectodomain proteolysis GO:0051043 25 12 0,000 0,05495474 0,08950295 ! positive regulation of blood pressure GO:0045777 18 12 0,000 0,05495474 0,08944332 ! cortical cytoskeleton organization GO:0030865 30 12 0,000 0,05495474 0,08938377 ! mating GO:0007618 17 12 0,000 0,05495474 0,0893243 ! protein complex disassembly GO:0043241 28 12 0,000 0,05495474 0,08926491 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,05495474 0,0892056 ! regulation of cell projection assembly GO:0060491 33 12 0,000 0,05495474 0,08914637 ! hippocampus development GO:0021766 29 12 0,000 0,05495474 0,08908721 ! positive regulation of transcription factor import into nucleus GO:0042993 25 12 0,000 0,05495474 0,08902813 ! cytokine biosynthetic process GO:0042089 23 12 0,000 0,05495474 0,08896914 ! T cell proliferation GO:0042098 32 12 0,000 0,05495474 0,08891022 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,05495474 0,08885137 ! regulation of exit from mitosis GO:0007096 19 12 0,000 0,05495474 0,08879261 ! ventral spinal cord development GO:0021517 25 12 0,000 0,05495474 0,08873392 ! glycolipid biosynthetic process GO:0009247 18 12 0,000 0,05495474 0,08867532 ! drug transport GO:0015893 16 12 0,000 0,05495474 0,08861678 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 23 12 0,000 0,05495474 0,08855833 ! oligodendrocyte differentiation GO:0048709 17 12 0,000 0,05495474 0,08849995 ! polyamine metabolic process GO:0006595 18 12 0,000 0,05495474 0,08844165 ! focal adhesion formation GO:0048041 37 12 0,000 0,05495474 0,08838343 ! mitotic spindle organization GO:0007052 23 12 0,000 0,05495474 0,08832528 ! negative regulation of endothelial cell migration GO:0010596 26 12 0,000 0,05495474 0,08826721 ! regulation of Cdc42 protein signal transduction GO:0032489 27 12 0,000 0,05495474 0,08820922 GO:0043088|regulation of Cdc42 GTPase activity, ! forebrain cell migration GO:0021885 24 12 0,000 0,05495474 0,0881513 ! lipid digestion GO:0044241 21 12 0,000 0,05495474 0,08809346 ! regulation of calcium ion transport into cytosol GO:0010522 17 12 0,000 0,05495474 0,08803569 ! entry into host cell GO:0030260 34 12 0,000 0,05495474 0,087978 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,05495474 0,08792038 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 25 12 0,000 0,05495474 0,08786285 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 20 12 0,000 0,05495474 0,08780538 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,05495474 0,08774799 ! protein targeting to peroxisome GO:0006625 27 12 0,000 0,05495474 0,08769068 ! negative regulation of myeloid leukocyte differentiation GO:0002762 17 12 0,000 0,05495474 0,08763344 ! regulation of phagocytosis GO:0050764 17 12 0,000 0,05495474 0,08757627 ! snRNA metabolic process GO:0016073 30 12 0,000 0,05495474 0,08751918 GO:0016180|snRNA processing, ! synaptic vesicle exocytosis GO:0016079 22 12 0,000 0,05495474 0,08746217 ! regulation of interleukin-8 production GO:0032677 22 12 0,000 0,05495474 0,08740523 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,05495474 0,08734836 ! cranial nerve development GO:0021545 23 12 0,000 0,05495474 0,08729157 ! fucose catabolic process GO:0019317 25 12 0,000 0,05495474 0,08723485 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 24 12 0,000 0,05495474 0,0871782 ! mRNA polyadenylation GO:0006378 24 12 0,000 0,05495474 0,08712163 ! autonomic nervous system development GO:0048483 24 12 0,000 0,05495474 0,08706513 ! zymogen activation GO:0031638 18 12 0,000 0,05495474 0,0870087 ! T cell homeostasis GO:0043029 28 12 0,000 0,05495474 0,08695235 ! regulation of interleukin-1 secretion GO:0050704 18 12 0,000 0,05495474 0,08689607 ! glutathione biosynthetic process GO:0006750 15 12 0,000 0,05495474 0,08683986 ! oocyte differentiation GO:0009994 21 12 0,000 0,05495474 0,08678373 ! leukocyte mediated cytotoxicity GO:0001909 28 12 0,000 0,05495474 0,08672767 ! quinone cofactor metabolic process GO:0042375 20 12 0,000 0,05495474 0,08667168 ! defense response to Gram-positive bacterium GO:0050830 14 12 0,000 0,05495474 0,08661576 ! defense response to fungus GO:0050832 15 12 0,000 0,05495474 0,08655991 ! lamellipodium assembly GO:0030032 24 12 0,000 0,05495474 0,08650414 ! response to cold GO:0009409 17 12 0,000 0,05495474 0,08644844 ! establishment of cell polarity GO:0030010 21 12 0,000 0,05495474 0,08639281 ! regulation of synapse organization GO:0050807 18 12 0,000 0,05495474 0,08633725 ! cell-substrate adhesion GO:0031589 189 82 1,000 0,05707833 0,08961592 ! protein import into nucleus GO:0006606 174 82 1,000 0,05707833 0,08955836 ! nuclear import GO:0051170 177 83 1,000 0,05831213 0,09143551 ! cGMP metabolic process GO:0046068 18 13 0,000 0,05939644 0,09307601 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 26 13 0,000 0,05939644 0,09301635 ! double-strand break repair via homologous recombination GO:0000724 19 13 0,000 0,05939644 0,09295676 GO:0000725|recombinational repair, ! folic acid and derivative biosynthetic process GO:0009396 25 13 0,000 0,05939644 0,09289725 ! peroxisomal transport GO:0043574 28 13 0,000 0,05939644 0,09283782 ! glycosaminoglycan catabolic process GO:0006027 15 13 0,000 0,05939644 0,09277846 ! negative regulation of transcription factor import into nucleus GO:0042992 31 13 0,000 0,05939644 0,09271917 ! organelle fusion GO:0048284 36 13 0,000 0,05939644 0,09265997 ! positive regulation of lipid metabolic process GO:0045834 30 13 0,000 0,05939644 0,09260083 ! negative regulation of lipid metabolic process GO:0045833 20 13 0,000 0,05939644 0,09254178 ! pseudouridine synthesis GO:0001522 19 13 0,000 0,05939644 0,0924828 ! endocrine pancreas development GO:0031018 25 13 0,000 0,05939644 0,09242389 ! positive regulation of cell growth GO:0030307 24 13 0,000 0,05939644 0,09236506 ! regulation of interferon-gamma biosynthetic process GO:0045072 19 13 0,000 0,05939644 0,0923063 ! two-component signal transduction system (phosphorelay) GO:0000160 22 13 0,000 0,05939644 0,09224762 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 28 13 0,000 0,05939644 0,09218901 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,05939644 0,09213048 ! methionine metabolic process GO:0006555 31 13 0,000 0,05939644 0,09207202 ! plasma membrane organization GO:0007009 27 13 0,000 0,05939644 0,09201364 ! ribonucleotide catabolic process GO:0009261 21 13 0,000 0,05939644 0,09195533 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 31 13 0,000 0,05939644 0,09189709 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 25 13 0,000 0,05939644 0,09183893 ! indolalkylamine metabolic process GO:0006586 19 13 0,000 0,05939644 0,09178084 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! cytokine metabolic process GO:0042107 24 13 0,000 0,05939644 0,09172282 ! cellular carbohydrate catabolic process GO:0044275 17 13 0,000 0,05939644 0,09166488 ! exocrine system development GO:0035272 34 13 0,000 0,05939644 0,09160701 ! asymmetric protein localization GO:0008105 24 13 0,000 0,05939644 0,09154921 ! membrane protein proteolysis GO:0033619 33 13 0,000 0,05939644 0,09149149 GO:0006509|membrane protein ectodomain proteolysis, ! monoamine transport GO:0015844 21 13 0,000 0,05939644 0,09143384 ! L-glutamate transport GO:0015813 30 13 0,000 0,05939644 0,09137626 GO:0015800|acidic amino acid transport, ! negative regulation of mitotic cell cycle GO:0045930 35 13 0,000 0,05939644 0,09131876 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 30 13 0,000 0,05939644 0,09126132 ! protein homotetramerization GO:0051289 24 13 0,000 0,05939644 0,09120396 ! regulation of cytokine production during immune response GO:0002718 25 13 0,000 0,05939644 0,09114667 ! regulation of natural killer cell mediated immunity GO:0002715 28 13 0,000 0,05939644 0,09108946 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 23 13 0,000 0,05939644 0,09103231 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 15 13 0,000 0,05939644 0,09097524 ! nucleoside triphosphate catabolic process GO:0009143 22 13 0,000 0,05939644 0,09091824 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,05939644 0,09086131 ! gastrulation with mouth forming second GO:0001702 29 13 0,000 0,05939644 0,09080445 ! histone methylation GO:0016571 29 13 0,000 0,05939644 0,09074766 ! chromatin silencing GO:0006342 29 13 0,000 0,05939644 0,09069094 ! gland morphogenesis GO:0022612 31 13 0,000 0,05939644 0,09063429 ! regulation of acute inflammatory response GO:0002673 24 13 0,000 0,05939644 0,09057772 ! regulation of epidermis development GO:0045682 19 13 0,000 0,05939644 0,09052121 ! positive regulation of T-helper cell differentiation GO:0045624 22 13 0,000 0,05939644 0,09046478 ! pyridine nucleotide biosynthetic process GO:0019363 24 13 0,000 0,05939644 0,09040841 ! spleen development GO:0048536 24 13 0,000 0,05939644 0,09035212 ! digestive tract morphogenesis GO:0048546 31 13 0,000 0,05939644 0,0902959 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 24 13 0,000 0,05939644 0,09023974 ! anterior/posterior axis specification GO:0009948 22 13 0,000 0,05939644 0,09018366 ! regulation of RNA splicing GO:0043484 22 13 0,000 0,05939644 0,09012764 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,05939644 0,0900717 ! regulation of fatty acid oxidation GO:0046320 34 13 0,000 0,05939644 0,09001582 ! positive regulation of homeostatic process GO:0032846 23 13 0,000 0,05939644 0,08996002 ! mRNA 3'-end processing GO:0031124 25 13 0,000 0,05939644 0,08990428 ! insulin secretion GO:0030073 24 13 0,000 0,05939644 0,08984861 ! positive regulation of calcium-mediated signaling GO:0050850 28 13 0,000 0,05939644 0,08979301 ! cytoplasmic sequestering of protein GO:0051220 25 13 0,000 0,05939644 0,08973748 ! acrosome reaction GO:0007340 19 13 0,000 0,05939644 0,08968202 ! regulation of synapse structure and activity GO:0050803 19 13 0,000 0,05939644 0,08962662 ! regulation of steroid biosynthetic process GO:0050810 20 13 0,000 0,05939644 0,0895713 ! response to metal ion GO:0010038 158 84 1,000 0,05955516 0,08975525 ! hemostasis GO:0007599 165 85 1,000 0,06080731 0,09158586 ! regulation of transmission of nerve impulse GO:0051969 167 85 1,000 0,06080731 0,09152943 ! cellular response to hormone stimulus GO:0032870 182 85 1,000 0,06080731 0,09147307 ! positive regulation of cell activation GO:0050867 161 86 1,000 0,06206848 0,09331279 GO:0002696|positive regulation of leukocyte activation, ! rRNA transcription GO:0009303 28 14 0,000 0,06381739 0,09588308 ! positive regulation of small GTPase mediated signal transduction GO:0051057 27 14 0,000 0,06381739 0,09582415 GO:0046579|positive regulation of Ras protein signal transduction, ! regulation of S phase GO:0033261 26 14 0,000 0,06381739 0,09576529 ! water transport GO:0006833 21 14 0,000 0,06381739 0,0957065 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 26 14 0,000 0,06381739 0,09564778 ! non-recombinational repair GO:0000726 29 14 0,000 0,06381739 0,09558914 GO:0006303|double-strand break repair via nonhomologous end joining, ! vesicle targeting, to, from or within Golgi GO:0048199 29 14 0,000 0,06381739 0,09553057 ! retina development in camera-type eye GO:0060041 28 14 0,000 0,06381739 0,09547207 ! hair follicle morphogenesis GO:0031069 27 14 0,000 0,06381739 0,09541364 ! RNA polyadenylation GO:0043631 32 14 0,000 0,06381739 0,09535528 ! lipid localization GO:0010876 32 14 0,000 0,06381739 0,095297 GO:0019915|lipid storage, ! palate development GO:0060021 32 14 0,000 0,06381739 0,09523878 ! regulated secretory pathway GO:0045055 24 14 0,000 0,06381739 0,09518064 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 29 14 0,000 0,06381739 0,09512257 ! nucleotide-sugar metabolic process GO:0009225 21 14 0,000 0,06381739 0,09506457 ! arginine metabolic process GO:0006525 21 14 0,000 0,06381739 0,09500663 ! deoxyribonucleotide catabolic process GO:0009264 21 14 0,000 0,06381739 0,09494877 ! regulation of heart rate GO:0002027 25 14 0,000 0,06381739 0,09489098 ! fear response GO:0042596 34 14 0,000 0,06381739 0,09483326 ! organic alcohol transport GO:0015850 29 14 0,000 0,06381739 0,09477562 ! negative regulation of caspase activity GO:0043154 23 14 0,000 0,06381739 0,09471804 ! branching involved in ureteric bud morphogenesis GO:0001658 31 14 0,000 0,06381739 0,09466053 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,06381739 0,09460309 ! neutral amino acid transport GO:0015804 28 14 0,000 0,06381739 0,09454572 ! bone mineralization GO:0030282 18 14 0,000 0,06381739 0,09448842 ! cotranslational protein targeting to membrane GO:0006613 26 14 0,000 0,06381739 0,09443119 ! RNA-dependent DNA replication GO:0006278 28 14 0,000 0,06381739 0,09437402 ! T cell differentiation in the thymus GO:0033077 37 14 0,000 0,06381739 0,09431693 ! cell wall macromolecule catabolic process GO:0016998 16 14 0,000 0,06381739 0,09425991 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 23 14 0,000 0,06381739 0,09420295 ! ribosome assembly GO:0042255 18 14 0,000 0,06381739 0,09414607 ! cerebellum development GO:0021549 23 14 0,000 0,06381739 0,09408925 ! positive regulation of Ras GTPase activity GO:0032320 42 14 0,000 0,06381739 0,0940325 ! regulation of T-helper 2 type immune response GO:0002828 25 14 0,000 0,06381739 0,09397582 ! negative regulation of protein secretion GO:0050709 30 14 0,000 0,06381739 0,09391921 ! positive regulation of bone mineralization GO:0030501 32 14 0,000 0,06381739 0,09386267 ! NADP metabolic process GO:0006739 24 14 0,000 0,06381739 0,09380619 ! serine family amino acid biosynthetic process GO:0009070 19 14 0,000 0,06381739 0,09374978 ! oxygen transport GO:0015671 22 14 0,000 0,06381739 0,09369344 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,06381739 0,09363717 ! male genitalia development GO:0030539 26 14 0,000 0,06381739 0,09358096 ! regulation of calcium-mediated signaling GO:0050848 29 14 0,000 0,06381739 0,09352483 ! positive regulation of protein polymerization GO:0032273 27 14 0,000 0,06381739 0,09346876 ! protein localization in nucleus GO:0034504 192 89 1,000 0,06590493 0,09646839 ! regulation of neurological system process GO:0031644 175 89 1,000 0,06590493 0,09641062 ! response to inorganic substance GO:0010035 173 90 1,000 0,06720103 0,09824783 ! response to unfolded protein GO:0006986 139 90 1,000 0,06720103 0,09818907 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,06821769 0,09961495 ! lactation GO:0007595 30 15 0,000 0,06821769 0,09955544 ! reproductive cellular process GO:0048610 22 15 0,000 0,06821769 0,09949601 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,06821769 0,09943664 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! tRNA modification GO:0006400 24 15 0,000 0,06821769 0,09937735 ! superoxide anion generation GO:0042554 22 15 0,000 0,06821769 0,09931812 ! pteridine and derivative biosynthetic process GO:0042559 20 15 0,000 0,06821769 0,09925897 ! phospholipid catabolic process GO:0009395 27 15 0,000 0,06821769 0,09919989 ! copper ion transport GO:0006825 22 15 0,000 0,06821769 0,09914087 ! positive regulation of GTPase activity GO:0043547 43 15 0,000 0,06821769 0,09908193 ! cardiac muscle contraction GO:0060048 28 15 0,000 0,06821769 0,09902306 ! regulation of cell-cell adhesion GO:0022407 35 15 0,000 0,06821769 0,09896426 ! sulfate transport GO:0008272 27 15 0,000 0,06821769 0,09890552 ! response to cAMP GO:0051591 25 15 0,000 0,06821769 0,09884686 ! regulation of excitatory postsynaptic membrane potential GO:0060079 33 15 0,000 0,06821769 0,09878827 ! negative regulation of cytokine biosynthetic process GO:0042036 25 15 0,000 0,06821769 0,09872974 ! response to hexose stimulus GO:0009746 25 15 0,000 0,06821769 0,09867129 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide biosynthetic process GO:0009220 24 15 0,000 0,06821769 0,0986129 ! glycoprotein catabolic process GO:0006516 33 15 0,000 0,06821769 0,09855459 ! vesicle coating GO:0006901 38 15 0,000 0,06821769 0,09849634 ! actin cytoskeleton reorganization GO:0031532 38 15 0,000 0,06821769 0,09843816 ! regulation of exocytosis GO:0017157 26 15 0,000 0,06821769 0,09838005 ! heparan sulfate proteoglycan metabolic process GO:0030201 35 15 0,000 0,06821769 0,09832201 ! intermediate filament cytoskeleton organization GO:0045104 34 15 0,000 0,06821769 0,09826404 ! positive regulation of axonogenesis GO:0050772 33 15 0,000 0,06821769 0,09820613 ! positive regulation of biomineral formation GO:0070169 33 15 0,000 0,06821769 0,0981483 ! regulation of vasodilation GO:0042312 27 15 0,000 0,06821769 0,09809053 ! regulation of T cell mediated immunity GO:0002709 36 15 0,000 0,06821769 0,09803283 ! water homeostasis GO:0030104 28 15 0,000 0,06821769 0,0979752 ! cofactor transport GO:0051181 30 15 0,000 0,06821769 0,09791763 ! protein-chromophore linkage GO:0018298 25 15 0,000 0,06821769 0,09786013 ! intestinal absorption GO:0050892 31 15 0,000 0,06821769 0,0978027 ! dopamine metabolic process GO:0042417 35 15 0,000 0,06821769 0,09774534 ! cAMP biosynthetic process GO:0006171 25 15 0,000 0,06821769 0,09768805 ! heme biosynthetic process GO:0006783 33 15 0,000 0,06821769 0,09763082 ! cell killing GO:0001906 32 15 0,000 0,06821769 0,09757366 ! lymphocyte homeostasis GO:0002260 33 15 0,000 0,06821769 0,09751656 ! positive regulation of calcium ion transport GO:0051928 21 15 0,000 0,06821769 0,09745954 ! L-fucose metabolic process GO:0042354 33 15 0,000 0,06821769 0,09740258 ! regulation of NF-kappaB import into nucleus GO:0042345 32 15 0,000 0,06821769 0,09734568 ! actin filament polymerization GO:0030041 27 15 0,000 0,06821769 0,09728886 ! cell wall macromolecule metabolic process GO:0044036 17 15 0,000 0,06821769 0,09723209 ! gland development GO:0048732 220 91 1,000 0,0685056 0,09758553 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 165 93 1,000 0,0711397 0,10127872 GO:0010498|proteasomal protein catabolic process, ! amine transport GO:0015837 181 93 1,000 0,0711397 0,10121973 ! nitrogen compound catabolic process GO:0044270 167 94 1,000 0,07246902 0,10305111 ! carbohydrate biosynthetic process GO:0016051 158 94 1,000 0,07246902 0,10299116 ! sulfur amino acid biosynthetic process GO:0000097 31 16 0,000 0,07259742 0,10311367 ! dicarboxylic acid transport GO:0006835 47 16 0,000 0,07259742 0,10305375 ! embryonic hindlimb morphogenesis GO:0035116 36 16 0,000 0,07259742 0,10299391 ! bone remodeling GO:0046849 28 16 0,000 0,07259742 0,10293413 ! heterophilic cell adhesion GO:0007157 43 16 0,000 0,07259742 0,10287442 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,07259742 0,10281479 ! regulation of neurotransmitter secretion GO:0046928 35 16 0,000 0,07259742 0,10275522 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 23 16 0,000 0,07259742 0,10269572 ! positive regulation of ion transport GO:0043270 23 16 0,000 0,07259742 0,10263629 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 34 16 0,000 0,07259742 0,10257693 ! startle response GO:0001964 28 16 0,000 0,07259742 0,10251763 ! regulation of transmembrane transporter activity GO:0022898 27 16 0,000 0,07259742 0,10245841 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 34 16 0,000 0,07259742 0,10239925 ! pyrimidine ribonucleotide metabolic process GO:0009218 27 16 0,000 0,07259742 0,10234016 ! protein polyubiquitination GO:0000209 41 16 0,000 0,07259742 0,10228114 ! glutamate metabolic process GO:0006536 25 16 0,000 0,07259742 0,10222219 ! pituitary gland development GO:0021983 30 16 0,000 0,07259742 0,10216331 ! response to osmotic stress GO:0006970 27 16 0,000 0,07259742 0,10210449 ! lysosomal transport GO:0007041 31 16 0,000 0,07259742 0,10204574 ! fructose metabolic process GO:0006000 25 16 0,000 0,07259742 0,10198706 ! L-amino acid transport GO:0015807 33 16 0,000 0,07259742 0,10192845 ! stem cell development GO:0048864 46 16 0,000 0,07259742 0,10186991 GO:0019827|stem cell maintenance, ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,07259742 0,10181143 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,07259742 0,10175301 ! intermediate filament-based process GO:0045103 36 16 0,000 0,07259742 0,10169467 ! NLS-bearing substrate import into nucleus GO:0006607 49 16 0,000 0,07259742 0,10163639 ! negative regulation of immune response GO:0050777 38 16 0,000 0,07259742 0,10157818 ! axon cargo transport GO:0008088 46 16 0,000 0,07259742 0,10152004 ! embryonic digit morphogenesis GO:0042733 36 16 0,000 0,07259742 0,10146196 ! nucleotide-excision repair, DNA gap filling GO:0006297 25 16 0,000 0,07259742 0,10140395 ! positive regulation of protein import into nucleus GO:0042307 34 16 0,000 0,07259742 0,101346 ! DNA replication initiation GO:0006270 28 16 0,000 0,07259742 0,10128812 ! mRNA splice site selection GO:0006376 44 16 0,000 0,07259742 0,10123031 ! tissue regeneration GO:0042246 27 16 0,000 0,07259742 0,10117256 ! positive regulation of cytokine secretion GO:0050715 29 16 0,000 0,07259742 0,10111488 ! negative regulation of inflammatory response GO:0050728 24 16 0,000 0,07259742 0,10105727 ! biomineral formation GO:0031214 22 16 0,000 0,07259742 0,10099972 ! neuromuscular synaptic transmission GO:0007274 34 16 0,000 0,07259742 0,10094223 ! C21-steroid hormone biosynthetic process GO:0006700 26 16 0,000 0,07259742 0,10088481 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,07259742 0,10082746 ! regulation of ATPase activity GO:0043462 26 16 0,000 0,07259742 0,10077017 ! aspartate family amino acid biosynthetic process GO:0009067 30 16 0,000 0,07259742 0,10071295 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 34 16 0,000 0,07259742 0,10065579 ! peptide hormone processing GO:0016486 27 16 0,000 0,07259742 0,1005987 ! negative regulation of multicellular organismal process GO:0051241 174 95 1,000 0,07380637 0,10221597 ! sex differentiation GO:0007548 171 96 1,000 0,07515167 0,10402013 ! response to protein stimulus GO:0051789 158 96 1,000 0,07515167 0,10396123 ! positive regulation of cell killing GO:0031343 36 17 0,000 0,0769567 0,10639797 ! metencephalon development GO:0022037 32 17 0,000 0,0769567 0,10633779 ! negative regulation of hormone secretion GO:0046888 26 17 0,000 0,0769567 0,10627768 ! signal complex assembly GO:0007172 47 17 0,000 0,0769567 0,10621763 ! filopodium assembly GO:0046847 42 17 0,000 0,0769567 0,10615766 ! endothelial cell migration GO:0043542 31 17 0,000 0,0769567 0,10609775 ! gene silencing by RNA GO:0031047 38 17 0,000 0,0769567 0,10603791 ! positive regulation of receptor-mediated endocytosis GO:0048260 24 17 0,000 0,0769567 0,10597813 ! glial cell development GO:0021782 28 17 0,000 0,0769567 0,10591843 ! regulation of muscle cell differentiation GO:0051147 36 17 0,000 0,0769567 0,10585879 ! negative regulation of peptidase activity GO:0010466 28 17 0,000 0,0769567 0,10579922 ! negative regulation of endothelial cell proliferation GO:0001937 38 17 0,000 0,0769567 0,10573971 ! negative regulation of gene expression, epigenetic GO:0045814 40 17 0,000 0,0769567 0,10568027 ! myoblast differentiation GO:0045445 50 17 0,000 0,0769567 0,1056209 ! activation of MAPKK activity GO:0000186 43 17 0,000 0,0769567 0,1055616 ! regulation of survival gene product expression GO:0045884 38 17 0,000 0,0769567 0,10550236 ! cardiac muscle tissue development GO:0048738 34 17 0,000 0,0769567 0,10544319 ! induction of apoptosis via death domain receptors GO:0008625 23 17 0,000 0,0769567 0,10538408 ! regulation of striated muscle contraction GO:0006942 23 17 0,000 0,0769567 0,10532505 ! complement activation, alternative pathway GO:0006957 19 17 0,000 0,0769567 0,10526607 ! NAD metabolic process GO:0019674 33 17 0,000 0,0769567 0,10520717 ! membrane budding GO:0006900 42 17 0,000 0,0769567 0,10514833 ! preassembly of GPI anchor in ER membrane GO:0016254 29 17 0,000 0,0769567 0,10508955 ! regulation of protein binding GO:0043393 33 17 0,000 0,0769567 0,10503084 ! nucleobase metabolic process GO:0009112 43 17 0,000 0,0769567 0,1049722 ! DNA unwinding during replication GO:0006268 26 17 0,000 0,0769567 0,10491362 ! genitalia development GO:0048806 32 17 0,000 0,0769567 0,10485511 ! regulation of immunoglobulin mediated immune response GO:0002889 35 17 0,000 0,0769567 0,10479666 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 30 17 0,000 0,0769567 0,10473828 ! negative regulation of blood coagulation GO:0030195 25 17 0,000 0,0769567 0,10467996 ! steroid catabolic process GO:0006706 34 17 0,000 0,0769567 0,10462171 ! activation of NF-kappaB-inducing kinase activity GO:0007250 30 17 0,000 0,0769567 0,10456352 ! branched chain family amino acid metabolic process GO:0009081 37 17 0,000 0,0769567 0,1045054 ! gas transport GO:0015669 26 17 0,000 0,0769567 0,10444734 ! organic cation transport GO:0015695 32 17 0,000 0,0769567 0,10438934 ! RNA 3'-end processing GO:0031123 37 17 0,000 0,0769567 0,10433141 ! antigen receptor-mediated signaling pathway GO:0050851 40 17 0,000 0,0769567 0,10427355 ! positive regulation of protein complex assembly GO:0031334 34 18 0,000 0,0812956 0,11009155 ! positive regulation of anti-apoptosis GO:0045768 47 18 0,000 0,0812956 0,11003055 ! phosphatidylcholine metabolic process GO:0046470 26 18 0,000 0,0812956 0,10996963 ! limbic system development GO:0021761 40 18 0,000 0,0812956 0,10990877 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,0812956 0,10984798 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 25 18 0,000 0,0812956 0,10978726 ! adult walking behavior GO:0007628 36 18 0,000 0,0812956 0,1097266 ! ciliary or flagellar motility GO:0001539 32 18 0,000 0,0812956 0,10966601 ! regulation of viral genome replication GO:0045069 30 18 0,000 0,0812956 0,10960549 ! centrosome cycle GO:0007098 26 18 0,000 0,0812956 0,10954504 ! positive regulation of proteolysis GO:0045862 36 18 0,000 0,0812956 0,10948465 ! regulation of defense response to virus GO:0050688 35 18 0,000 0,0812956 0,10942432 ! epidermis morphogenesis GO:0048730 43 18 0,000 0,0812956 0,10936407 ! glycine metabolic process GO:0006544 30 18 0,000 0,0812956 0,10930388 ! glutamine metabolic process GO:0006541 29 18 0,000 0,0812956 0,10924376 ! response to retinoic acid GO:0032526 31 18 0,000 0,0812956 0,1091837 ! cell-substrate junction assembly GO:0007044 56 18 0,000 0,0812956 0,10912371 ! pyrimidine ribonucleoside metabolic process GO:0046131 26 18 0,000 0,0812956 0,10906378 ! DNA integration GO:0015074 32 18 0,000 0,0812956 0,10900392 ! negative regulation of protein catabolic process GO:0042177 42 18 0,000 0,0812956 0,10894413 ! positive regulation of alpha-beta T cell differentiation GO:0046638 31 18 0,000 0,0812956 0,1088844 ! ventricular cardiac muscle morphogenesis GO:0055010 30 18 0,000 0,0812956 0,10882474 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 29 18 0,000 0,0812956 0,10876514 ! long-chain fatty acid transport GO:0015909 32 18 0,000 0,0812956 0,10870561 ! sphingolipid catabolic process GO:0030149 32 18 0,000 0,0812956 0,10864614 GO:0046466|membrane lipid catabolic process, ! regulation of immunoglobulin production GO:0002637 49 18 0,000 0,0812956 0,10858674 ! porphyrin biosynthetic process GO:0006779 37 18 0,000 0,0812956 0,1085274 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 33 18 0,000 0,0812956 0,10846813 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 36 18 0,000 0,0812956 0,10840892 ! aromatic compound biosynthetic process GO:0019438 26 18 0,000 0,0812956 0,10834978 ! detection of bacterium GO:0016045 22 18 0,000 0,0812956 0,1082907 ! nerve development GO:0021675 34 18 0,000 0,0812956 0,10823169 ! defense response to virus GO:0051607 43 18 0,000 0,0812956 0,10817274 ! microspike assembly GO:0030035 46 18 0,000 0,0812956 0,10811385 ! positive regulation of synaptic transmission GO:0050806 35 18 0,000 0,0812956 0,10805503 ! oligosaccharide metabolic process GO:0009311 38 19 0,000 0,08561423 0,11373331 ! negative regulation of defense response GO:0031348 27 19 0,000 0,08561423 0,1136715 ! G1 phase of mitotic cell cycle GO:0000080 39 19 0,000 0,08561423 0,11360976 ! neuron maturation GO:0042551 46 19 0,000 0,08561423 0,11354808 ! regulation of lipid biosynthetic process GO:0046890 28 19 0,000 0,08561423 0,11348647 ! positive regulation of hormone secretion GO:0046887 35 19 0,000 0,08561423 0,11342492 ! 2'-deoxyribonucleotide metabolic process GO:0009394 31 19 0,000 0,08561423 0,11336345 GO:0019692|deoxyribose phosphate metabolic process, ! protein amino acid ADP-ribosylation GO:0006471 37 19 0,000 0,08561423 0,11330204 ! inositol metabolic process GO:0006020 33 19 0,000 0,08561423 0,11324069 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,08561423 0,11317942 ! memory GO:0007613 34 19 0,000 0,08561423 0,11311821 ! regulation of postsynaptic membrane potential GO:0060078 38 19 0,000 0,08561423 0,11305706 ! cellular response to hydrogen peroxide GO:0070301 25 19 0,000 0,08561423 0,11299598 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 37 19 0,000 0,08561423 0,11293497 ! cell differentiation in spinal cord GO:0021515 37 19 0,000 0,08561423 0,11287402 ! cerebral cortex development GO:0021987 40 19 0,000 0,08561423 0,11281314 ! pigmentation during development GO:0048066 42 19 0,000 0,08561423 0,11275232 ! response to vitamin A GO:0033189 32 19 0,000 0,08561423 0,11269157 ! heme metabolic process GO:0042168 40 19 0,000 0,08561423 0,11263089 ! response to lipopolysaccharide GO:0032496 34 19 0,000 0,08561423 0,11257027 ! response to fungus GO:0009620 26 19 0,000 0,08561423 0,11250972 ! peptide cross-linking GO:0018149 39 19 0,000 0,08561423 0,11244923 ! protein export from nucleus GO:0006611 40 19 0,000 0,08561423 0,1123888 ! heart process GO:0003015 32 19 0,000 0,08561423 0,11232844 GO:0060047|heart contraction, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 30 19 0,000 0,08561423 0,11226815 ! regulation of steroid metabolic process GO:0019218 35 19 0,000 0,08561423 0,11220792 ! visual learning GO:0008542 38 19 0,000 0,08561423 0,11214775 ! cellular pigmentation GO:0033059 37 19 0,000 0,08561423 0,11208765 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 35 19 0,000 0,08561423 0,11202762 ! peptide biosynthetic process GO:0043043 26 19 0,000 0,08561423 0,11196765 ! vitamin transport GO:0051180 31 19 0,000 0,08561423 0,11190774 ! folic acid and derivative metabolic process GO:0006760 39 19 0,000 0,08561423 0,11184789 ! positive regulation of transmission of nerve impulse GO:0051971 36 19 0,000 0,08561423 0,11178811 ! somatic recombination of immunoglobulin gene segments GO:0016447 52 19 0,000 0,08561423 0,1117284 ! embryonic organ morphogenesis GO:0048562 34 19 0,000 0,08561423 0,11166875 ! cilium assembly GO:0042384 38 19 0,000 0,08561423 0,11160916 ! peptide hormone secretion GO:0030072 32 19 0,000 0,08561423 0,11154963 ! protein secretion GO:0009306 45 20 0,000 0,08991268 0,11708778 ! protein import into nucleus, docking GO:0000059 42 20 0,000 0,08991268 0,1170254 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 32 20 0,000 0,08991268 0,11696308 ! positive regulation of ossification GO:0045778 50 20 0,000 0,08991268 0,11690084 ! skin development GO:0043588 42 20 0,000 0,08991268 0,11683866 ! phosphoinositide phosphorylation GO:0046854 40 20 0,000 0,08991268 0,11677654 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 40 20 0,000 0,08991268 0,11671449 ! aminoglycan catabolic process GO:0006026 25 20 0,000 0,08991268 0,11665251 ! response to vitamin GO:0033273 36 20 0,000 0,08991268 0,11659059 ! transcription from RNA polymerase III promoter GO:0006383 46 20 0,000 0,08991268 0,11652874 ! bile acid metabolic process GO:0008206 34 20 0,000 0,08991268 0,11646695 ! response to alkaloid GO:0043279 38 20 0,000 0,08991268 0,11640523 ! retinoid metabolic process GO:0001523 34 20 0,000 0,08991268 0,11634358 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 40 20 0,000 0,08991268 0,11628199 ! response to carbohydrate stimulus GO:0009743 33 20 0,000 0,08991268 0,11622046 ! DNA duplex unwinding GO:0032508 30 20 0,000 0,08991268 0,116159 GO:0032392|DNA geometric change, ! cellular response to unfolded protein GO:0034620 35 20 0,000 0,08991268 0,11609761 GO:0030968|endoplasmic reticulum unfolded protein response, ! actin filament bundle formation GO:0051017 47 20 0,000 0,08991268 0,11603628 ! body fluid secretion GO:0007589 33 20 0,000 0,08991268 0,11597501 ! fatty acid beta-oxidation GO:0006635 36 20 0,000 0,08991268 0,11591381 ! peptide secretion GO:0002790 38 20 0,000 0,08991268 0,11585268 ! behavioral interaction between organisms GO:0051705 47 20 0,000 0,08991268 0,1157916 ! regulation of fatty acid metabolic process GO:0019217 45 20 0,000 0,08991268 0,1157306 ! protein localization in mitochondrion GO:0070585 39 20 0,000 0,08991268 0,11566965 GO:0006626|protein targeting to mitochondrion, ! positive regulation of neurological system process GO:0031646 39 20 0,000 0,08991268 0,11560878 ! negative regulation of myeloid cell differentiation GO:0045638 32 20 0,000 0,08991268 0,11554796 ! purine nucleotide catabolic process GO:0006195 32 20 0,000 0,08991268 0,11548721 ! regulation of leukocyte mediated cytotoxicity GO:0001910 44 20 0,000 0,08991268 0,11542652 ! estrogen receptor signaling pathway GO:0030520 45 20 0,000 0,08991268 0,1153659 ! binding of sperm to zona pellucida GO:0007339 22 20 0,000 0,08991268 0,11530534 ! negative regulation of translation GO:0017148 32 20 0,000 0,08991268 0,11524484 ! negative regulation of coagulation GO:0050819 30 20 0,000 0,08991268 0,11518441 ! regulation of cell killing GO:0031341 46 21 0,000 0,09419104 0,12060205 ! phosphatidylinositol metabolic process GO:0046488 47 21 0,000 0,09419104 0,12053888 ! hormone secretion GO:0046879 39 21 0,000 0,09419104 0,12047577 ! lipid phosphorylation GO:0046834 43 21 0,000 0,09419104 0,12041272 ! cAMP metabolic process GO:0046058 41 21 0,000 0,09419104 0,12034975 ! regulation of neurotransmitter transport GO:0051588 44 21 0,000 0,09419104 0,12028684 ! gamma-aminobutyric acid signaling pathway GO:0007214 31 21 0,000 0,09419104 0,12022399 ! C21-steroid hormone metabolic process GO:0008207 38 21 0,000 0,09419104 0,12016121 ! ovarian follicle development GO:0001541 39 21 0,000 0,09419104 0,12009849 ! smooth muscle contraction GO:0006939 48 21 0,000 0,09419104 0,12003585 ! cellular macromolecular complex disassembly GO:0034623 44 21 0,000 0,09419104 0,11997326 ! neurotransmitter metabolic process GO:0042133 39 21 0,000 0,09419104 0,11991074 ! positive regulation of alpha-beta T cell activation GO:0046635 38 21 0,000 0,09419104 0,11984829 ! prostaglandin metabolic process GO:0006693 43 21 0,000 0,09419104 0,1197859 GO:0006692|prostanoid metabolic process, ! regulation of vasoconstriction GO:0019229 40 21 0,000 0,09419104 0,11972358 ! sensory perception of pain GO:0019233 33 21 0,000 0,09419104 0,11966132 ! ribosomal small subunit biogenesis GO:0042274 25 21 0,000 0,09419104 0,11959912 ! diencephalon development GO:0021536 36 21 0,000 0,09419104 0,119537 ! collagen fibril organization GO:0030199 62 21 0,000 0,09419104 0,11947493 ! negative regulation of angiogenesis GO:0016525 49 21 0,000 0,09419104 0,11941293 ! vitamin A metabolic process GO:0006776 35 21 0,000 0,09419104 0,11935099 ! positive regulation of osteoblast differentiation GO:0045669 52 21 0,000 0,09419104 0,11928912 ! collagen catabolic process GO:0030574 29 21 0,000 0,09419104 0,11922731 ! leukotriene biosynthetic process GO:0019370 42 21 0,000 0,09419104 0,11916557 GO:0043450|alkene biosynthetic process, ! camera-type eye morphogenesis GO:0048593 47 21 0,000 0,09419104 0,11910389 ! sperm-egg recognition GO:0035036 23 21 0,000 0,09419104 0,11904227 ! actin filament-based movement GO:0030048 47 21 0,000 0,09419104 0,11898072 ! pteridine and derivative metabolic process GO:0042558 32 22 0,000 0,09844941 0,12429556 ! reciprocal meiotic recombination GO:0007131 44 22 0,000 0,09844941 0,12423136 ! cellular aldehyde metabolic process GO:0006081 35 22 0,000 0,09844941 0,12416722 ! positive regulation of bone remodeling GO:0046852 54 22 0,000 0,09844941 0,12410316 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 59 22 0,000 0,09844941 0,12403915 ! vacuolar transport GO:0007034 41 22 0,000 0,09844941 0,12397521 ! central nervous system neuron development GO:0021954 47 22 0,000 0,09844941 0,12391134 ! fucose metabolic process GO:0006004 44 22 0,000 0,09844941 0,12384754 ! actin polymerization or depolymerization GO:0008154 52 22 0,000 0,09844941 0,1237838 ! D-ribose metabolic process GO:0006014 36 22 0,000 0,09844941 0,12372012 ! ureteric bud development GO:0001657 50 22 0,000 0,09844941 0,12365651 ! stem cell differentiation GO:0048863 57 22 0,000 0,09844941 0,12359297 ! regulation of myeloid leukocyte differentiation GO:0002761 41 22 0,000 0,09844941 0,12352949 ! cytolysis GO:0019835 27 22 0,000 0,09844941 0,12346608 ! renal system process GO:0003014 42 22 0,000 0,09844941 0,12340273 ! vasodilation GO:0042311 40 22 0,000 0,09844941 0,12333944 ! cholesterol biosynthetic process GO:0006695 39 22 0,000 0,09844941 0,12327622 ! G1 phase GO:0051318 44 22 0,000 0,09844941 0,12321307 ! detection of chemical stimulus GO:0009593 42 22 0,000 0,09844941 0,12314998 ! positive regulation of adaptive immune response GO:0002821 42 22 0,000 0,09844941 0,12308696 ! regulation of cytokine secretion GO:0050707 41 22 0,000 0,09844941 0,123024 ! sphingolipid biosynthetic process GO:0030148 45 22 0,000 0,09844941 0,1229611 ! sarcomere organization GO:0045214 32 22 0,000 0,09844941 0,12289827 ! response to cytokine stimulus GO:0034097 69 22 0,000 0,09844941 0,1228355 ! activation of JUN kinase activity GO:0007257 47 22 0,000 0,09844941 0,1227728 ! terpenoid metabolic process GO:0006721 40 22 0,000 0,09844941 0,12271016 ! somatic diversification of immunoglobulins GO:0016445 55 22 0,000 0,09844941 0,12264759 ! gut development GO:0048565 44 22 0,000 0,09844941 0,12258507 ! pyrimidine nucleotide biosynthetic process GO:0006221 37 22 0,000 0,09844941 0,12252263 ! protein stabilization GO:0050821 41 22 0,000 0,09844941 0,12246024 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 29 23 0,000 0,10268788 0,12766743 ! regulation of anti-apoptosis GO:0045767 62 23 0,000 0,10268788 0,12760249 ! sulfur amino acid metabolic process GO:0000096 48 23 0,000 0,10268788 0,12753762 ! glycerol metabolic process GO:0006071 40 23 0,000 0,10268788 0,12747281 ! viral genome replication GO:0019079 44 23 0,000 0,10268788 0,12740807 ! nucleotide-excision repair, DNA damage removal GO:0000718 36 23 0,000 0,10268788 0,1273434 ! glucosamine metabolic process GO:0006041 31 23 0,000 0,10268788 0,12727879 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 32 23 0,000 0,10268788 0,12721425 ! regeneration GO:0031099 42 23 0,000 0,10268788 0,12714977 ! axis specification GO:0009798 43 23 0,000 0,10268788 0,12708536 ! visual behavior GO:0007632 46 23 0,000 0,10268788 0,12702101 ! regulation of DNA recombination GO:0000018 51 23 0,000 0,10268788 0,12695673 ! response to ethanol GO:0045471 47 23 0,000 0,10268788 0,12689251 ! photoreceptor cell maintenance GO:0045494 41 23 0,000 0,10268788 0,12682836 ! activation of pro-apoptotic gene products GO:0008633 51 23 0,000 0,10268788 0,12676427 ! deoxyribonucleotide metabolic process GO:0009262 37 23 0,000 0,10268788 0,12670025 ! peroxisome organization GO:0007031 43 23 0,000 0,10268788 0,12663629 ! lysosome organization GO:0007040 47 23 0,000 0,10268788 0,1265724 ! cellular response to reactive oxygen species GO:0034614 35 23 0,000 0,10268788 0,12650857 ! vesicle targeting GO:0006903 49 23 0,000 0,10268788 0,12644481 ! cardiac muscle tissue morphogenesis GO:0055008 37 23 0,000 0,10268788 0,12638111 GO:0060415|muscle tissue morphogenesis, ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 40 23 0,000 0,10268788 0,12631747 ! regulation of interleukin-6 production GO:0032675 31 23 0,000 0,10268788 0,1262539 ! regulation of Rho GTPase activity GO:0032319 56 23 0,000 0,10268788 0,12619039 ! DNA modification GO:0006304 36 23 0,000 0,10268788 0,12612695 ! fatty acid transport GO:0015908 47 23 0,000 0,10268788 0,12606357 ! regulation of bone mineralization GO:0030500 54 23 0,000 0,10268788 0,12600025 ! hormone transport GO:0009914 41 23 0,000 0,10268788 0,125937 ! cell-cell recognition GO:0009988 28 23 0,000 0,10268788 0,12587381 ! negative regulation of cytokine production GO:0001818 41 23 0,000 0,10268788 0,12581068 ! acetyl-CoA catabolic process GO:0046356 37 23 0,000 0,10268788 0,12574762 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 40 23 0,000 0,10268788 0,12568462 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 35 24 0,000 0,10690655 0,13078252 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 61 24 0,000 0,10690655 0,13071706 GO:0016444|somatic cell DNA recombination, ! membrane lipid biosynthetic process GO:0046467 47 24 0,000 0,10690655 0,13065167 ! protein amino acid O-linked glycosylation GO:0006493 45 24 0,000 0,10690655 0,13058635 ! post-Golgi vesicle-mediated transport GO:0006892 62 24 0,000 0,10690655 0,13052109 ! glycosaminoglycan biosynthetic process GO:0006024 51 24 0,000 0,10690655 0,13045589 ! calcium-independent cell-cell adhesion GO:0016338 36 24 0,000 0,10690655 0,13039076 ! immune response-activating cell surface receptor signaling pathway GO:0002429 49 24 0,000 0,10690655 0,13032569 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! central nervous system neuron differentiation GO:0021953 51 24 0,000 0,10690655 0,13026069 ! purine ribonucleoside metabolic process GO:0046128 38 24 0,000 0,10690655 0,13019576 GO:0042278|purine nucleoside metabolic process, ! positive regulation of cytoskeleton organization GO:0051495 52 24 0,000 0,10690655 0,13013089 ! barbed-end actin filament capping GO:0051016 58 24 0,000 0,10690655 0,13006608 GO:0051693|actin filament capping, ! regulation of viral reproduction GO:0050792 41 24 0,000 0,10690655 0,13000134 ! positive regulation of leukocyte mediated immunity GO:0002705 47 24 0,000 0,10690655 0,12993666 GO:0002708|positive regulation of lymphocyte mediated immunity, ! leukotriene metabolic process GO:0006691 47 24 0,000 0,10690655 0,12987205 ! glycosphingolipid metabolic process GO:0006687 44 24 0,000 0,10690655 0,1298075 ! regulation of tumor necrosis factor production GO:0032680 37 24 0,000 0,10690655 0,12974302 ! membrane depolarization GO:0051899 45 24 0,000 0,10690655 0,1296786 ! pallium development GO:0021543 56 24 0,000 0,10690655 0,12961424 ! oogenesis GO:0048477 44 24 0,000 0,10690655 0,12954995 ! synaptic vesicle transport GO:0048489 52 24 0,000 0,10690655 0,12948572 ! detection of biotic stimulus GO:0009595 34 24 0,000 0,10690655 0,12942155 ! glutamine family amino acid catabolic process GO:0009065 45 24 0,000 0,10690655 0,12935745 ! aspartate family amino acid metabolic process GO:0009066 47 24 0,000 0,10690655 0,12929341 ! porphyrin metabolic process GO:0006778 50 24 0,000 0,10690655 0,12922944 GO:0033013|tetrapyrrole metabolic process, ! pyrimidine nucleoside metabolic process GO:0006213 34 24 0,000 0,10690655 0,12916552 ! negative regulation of catabolic process GO:0009895 52 24 0,000 0,10690655 0,12910168 ! regulation of amine transport GO:0051952 41 24 0,000 0,10690655 0,12903789 ! regulation of transmembrane transport GO:0034762 39 25 0,000 0,11110549 0,13403986 ! leukocyte adhesion GO:0007159 55 25 0,000 0,11110549 0,1339737 ! dicarboxylic acid metabolic process GO:0043648 48 25 0,000 0,11110549 0,13390761 ! phototransduction GO:0007602 37 25 0,000 0,11110549 0,13384158 ! keratinization GO:0031424 37 25 0,000 0,11110549 0,13377561 ! vacuole organization GO:0007033 49 25 0,000 0,11110549 0,13370971 ! polysaccharide catabolic process GO:0000272 30 25 0,000 0,11110549 0,13364388 ! receptor metabolic process GO:0043112 53 25 0,000 0,11110549 0,13357811 ! chromosome condensation GO:0030261 48 25 0,000 0,11110549 0,13351241 ! regulation of insulin secretion GO:0050796 42 25 0,000 0,11110549 0,13344676 ! lymphocyte proliferation GO:0046651 55 25 0,000 0,11110549 0,13338119 ! regulation of biomineral formation GO:0070167 56 25 0,000 0,11110549 0,13331568 ! immunoglobulin production GO:0002377 62 25 0,000 0,11110549 0,13325023 GO:0002440|production of molecular mediator of immune response, ! positive regulation of protein secretion GO:0050714 41 25 0,000 0,11110549 0,13318485 ! leukocyte homeostasis GO:0001776 50 25 0,000 0,11110549 0,13311953 ! cellular alkene metabolic process GO:0043449 48 25 0,000 0,11110549 0,13305427 ! liver development GO:0001889 55 25 0,000 0,11110549 0,13298908 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 36 26 0,000 0,11528482 0,137924 ! initiation of viral infection GO:0019059 60 26 0,000 0,11528482 0,13785649 ! aminoglycan biosynthetic process GO:0006023 53 26 0,000 0,11528482 0,13778904 ! molting cycle process GO:0022404 52 26 0,000 0,11528482 0,13772167 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! macromolecular complex disassembly GO:0032984 54 26 0,000 0,11528482 0,13765435 ! protein amino acid alkylation GO:0008213 59 26 0,000 0,11528482 0,13758711 GO:0006479|protein amino acid methylation, ! regulation of transcription factor import into nucleus GO:0042990 58 26 0,000 0,11528482 0,13751992 ! microtubule organizing center organization GO:0031023 42 26 0,000 0,11528482 0,13745281 GO:0051297|centrosome organization, ! spinal cord development GO:0021510 54 26 0,000 0,11528482 0,13738576 ! regulation of smooth muscle contraction GO:0006940 48 26 0,000 0,11528482 0,13731877 ! multicellular organismal response to stress GO:0033555 61 26 0,000 0,11528482 0,13725185 ! digestive system process GO:0022600 49 26 0,000 0,11528482 0,137185 ! vesicle docking during exocytosis GO:0006904 49 26 0,000 0,11528482 0,13711821 ! regulation of cellular ketone metabolic process GO:0010565 51 26 0,000 0,11528482 0,13705149 ! osteoblast differentiation GO:0001649 63 26 0,000 0,11528482 0,13698483 ! coenzyme catabolic process GO:0009109 42 26 0,000 0,11528482 0,13691823 ! hydrogen peroxide metabolic process GO:0042743 35 26 0,000 0,11528482 0,1368517 ! ribonucleoside monophosphate metabolic process GO:0009161 45 26 0,000 0,11528482 0,13678524 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! pentose metabolic process GO:0019321 43 26 0,000 0,11528482 0,13671884 ! response to estradiol stimulus GO:0032355 43 26 0,000 0,11528482 0,1366525 ! positive regulation of MAPKKK cascade GO:0043410 50 26 0,000 0,11528482 0,13658623 ! regulation of blood coagulation GO:0030193 46 26 0,000 0,11528482 0,13652002 ! regulation of osteoblast differentiation GO:0045667 68 26 0,000 0,11528482 0,13645388 ! somatic diversification of immune receptors GO:0002200 63 26 0,000 0,11528482 0,1363878 ! blastocyst development GO:0001824 50 26 0,000 0,11528482 0,13632178 ! telomere organization GO:0032200 46 26 0,000 0,11528482 0,13625583 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 44 26 0,000 0,11528482 0,13618994 ! alditol metabolic process GO:0019400 44 26 0,000 0,11528482 0,13612412 ! positive regulation of JUN kinase activity GO:0043507 59 26 0,000 0,11528482 0,13605836 ! regulation of multi-organism process GO:0043900 45 26 0,000 0,11528482 0,13599266 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 31 27 0,000 0,11944461 0,14083165 ! embryonic pattern specification GO:0009880 49 27 0,000 0,11944461 0,14076371 ! negative regulation of actin filament depolymerization GO:0030835 63 27 0,000 0,11944461 0,14069584 ! negative regulation of actin filament polymerization GO:0030837 61 27 0,000 0,11944461 0,14062804 ! positive regulation of cell projection organization GO:0031346 66 27 0,000 0,11944461 0,1405603 ! regulation of interferon-gamma production GO:0032649 43 27 0,000 0,11944461 0,14049262 ! acetyl-CoA metabolic process GO:0006084 41 27 0,000 0,11944461 0,14042501 ! iron ion transport GO:0006826 65 27 0,000 0,11944461 0,14035747 ! cellular polysaccharide biosynthetic process GO:0033692 41 27 0,000 0,11944461 0,14028999 ! superoxide metabolic process GO:0006801 41 27 0,000 0,11944461 0,14022257 ! odontogenesis of dentine-containing tooth GO:0042475 54 27 0,000 0,11944461 0,14015522 ! multicellular organismal catabolic process GO:0044243 38 27 0,000 0,11944461 0,14008794 ! fat-soluble vitamin metabolic process GO:0006775 42 27 0,000 0,11944461 0,14002072 ! leukocyte proliferation GO:0070661 59 27 0,000 0,11944461 0,13995356 GO:0032943|mononuclear cell proliferation, ! spliceosomal snRNP biogenesis GO:0000387 40 28 0,000 0,12358496 0,1447354 ! vesicle docking GO:0048278 55 28 0,000 0,12358496 0,14466605 ! fat cell differentiation GO:0045444 57 28 0,000 0,12358496 0,14459676 ! positive regulation of innate immune response GO:0045089 49 28 0,000 0,12358496 0,14452755 ! sperm motility GO:0030317 37 28 0,000 0,12358496 0,14445839 ! vitamin biosynthetic process GO:0009110 48 28 0,000 0,12358496 0,14438931 ! cyclic nucleotide biosynthetic process GO:0009190 43 28 0,000 0,12358496 0,14432029 ! regulation of systemic arterial blood pressure GO:0003073 55 28 0,000 0,12358496 0,14425134 ! positive regulation of T cell differentiation GO:0045582 48 28 0,000 0,12358496 0,14418245 ! glycolipid metabolic process GO:0006664 50 28 0,000 0,12358496 0,14411363 ! proteoglycan biosynthetic process GO:0030166 62 28 0,000 0,12358496 0,14404487 ! regulation of response to biotic stimulus GO:0002831 52 28 0,000 0,12358496 0,14397618 ! glutathione metabolic process GO:0006749 42 28 0,000 0,12358496 0,14390755 ! group transfer coenzyme metabolic process GO:0006752 53 28 0,000 0,12358496 0,14383899 ! lipid oxidation GO:0034440 48 28 0,000 0,12358496 0,1437705 GO:0019395|fatty acid oxidation, ! regulation of JUN kinase activity GO:0043506 67 28 0,000 0,12358496 0,14370207 ! negative regulation of protein polymerization GO:0032272 63 28 0,000 0,12358496 0,1436337 ! translational initiation GO:0006413 66 29 0,000 0,12770595 0,14835266 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 57 29 0,000 0,12770595 0,14828215 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! catechol metabolic process GO:0009712 55 29 0,000 0,12770595 0,14821171 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! autophagy GO:0006914 47 29 0,000 0,12770595 0,14814133 ! respiratory gaseous exchange GO:0007585 61 29 0,000 0,12770595 0,14807102 ! regulation of peptide secretion GO:0002791 52 29 0,000 0,12770595 0,14800078 ! regulation of production of molecular mediator of immune response GO:0002700 69 29 0,000 0,12770595 0,1479306 ! synaptogenesis GO:0007416 46 29 0,000 0,12770595 0,14786049 ! neuromuscular process controlling balance GO:0050885 67 29 0,000 0,12770595 0,14779045 ! ethanolamine and derivative metabolic process GO:0042439 48 29 0,000 0,12770595 0,14772047 ! negative regulation of neuron apoptosis GO:0043524 69 29 0,000 0,12770595 0,14765056 ! regulation of actin filament depolymerization GO:0030834 67 30 0,000 0,13180769 0,1523208 ! phenol metabolic process GO:0018958 56 30 0,000 0,13180769 0,15224878 ! negative regulation of protein complex assembly GO:0031333 68 30 0,000 0,13180769 0,15217683 ! icosanoid biosynthetic process GO:0046456 60 30 0,000 0,13180769 0,15210495 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 56 30 0,000 0,13180769 0,15203313 ! detection of light stimulus involved in sensory perception GO:0050962 42 30 0,000 0,13180769 0,15196139 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! sensory perception of taste GO:0050909 41 30 0,000 0,13180769 0,15188971 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 50 30 0,000 0,13180769 0,15181809 ! acute-phase response GO:0006953 50 30 0,000 0,13180769 0,15174655 ! complement activation, classical pathway GO:0006958 51 30 0,000 0,13180769 0,15167507 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 58 30 0,000 0,13180769 0,15160366 ! myofibril assembly GO:0030239 50 30 0,000 0,13180769 0,15153232 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 72 30 0,000 0,13180769 0,15146104 ! immune response-activating signal transduction GO:0002757 58 30 0,000 0,13180769 0,15138983 GO:0002764|immune response-regulating signal transduction, ! determination of left/right symmetry GO:0007368 53 30 0,000 0,13180769 0,15131869 ! cell fate determination GO:0001709 64 30 0,000 0,13180769 0,15124762 ! positive regulation of multicellular organism growth GO:0040018 55 30 0,000 0,13180769 0,15117661 ! phospholipid transport GO:0015914 65 30 0,000 0,13180769 0,15110567 ! sterol biosynthetic process GO:0016126 56 30 0,000 0,13180769 0,15103479 ! nicotinamide metabolic process GO:0006769 56 30 0,000 0,13180769 0,15096398 GO:0046496|nicotinamide nucleotide metabolic process, ! neurotransmitter secretion GO:0007269 55 30 0,000 0,13180769 0,15089324 ! regulation of coagulation GO:0050818 52 30 0,000 0,13180769 0,15082257 ! alkaloid metabolic process GO:0009820 57 31 0,000 0,13589025 0,15542129 ! determination of bilateral symmetry GO:0009855 55 31 0,000 0,13589025 0,15534856 GO:0009799|determination of symmetry, ! zinc ion transport GO:0006829 54 31 0,000 0,13589025 0,1552759 ! amino sugar metabolic process GO:0006040 41 31 0,000 0,13589025 0,15520331 ! regulation of innate immune response GO:0045088 57 31 0,000 0,13589025 0,15513078 ! ovulation cycle process GO:0022602 55 31 0,000 0,13589025 0,15505833 ! peptide transport GO:0015833 60 31 0,000 0,13589025 0,15498594 ! erythrocyte differentiation GO:0030218 62 31 0,000 0,13589025 0,15491362 ! detection of light stimulus GO:0009583 44 31 0,000 0,13589025 0,15484136 ! natural killer cell activation GO:0030101 50 31 0,000 0,13589025 0,15476917 ! cofactor catabolic process GO:0051187 54 31 0,000 0,13589025 0,15469705 ! fatty acid catabolic process GO:0009062 54 31 0,000 0,13589025 0,154625 ! eye morphogenesis GO:0048592 65 31 0,000 0,13589025 0,15455302 ! positive regulation of immune effector process GO:0002699 78 31 0,000 0,13589025 0,1544811 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 54 32 0,000 0,13995373 0,15902649 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 50 32 0,000 0,13995373 0,15895256 ! cellular carbohydrate biosynthetic process GO:0034637 47 32 0,000 0,13995373 0,1588787 ! positive regulation of T cell proliferation GO:0042102 60 32 0,000 0,13995373 0,1588049 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 54 32 0,000 0,13995373 0,15873118 ! response to mechanical stimulus GO:0009612 60 32 0,000 0,13995373 0,15865752 ! muscle cell development GO:0055001 52 32 0,000 0,13995373 0,15858393 ! mesoderm formation GO:0001707 73 32 0,000 0,13995373 0,15851041 ! ovulation cycle GO:0042698 57 32 0,000 0,13995373 0,15843696 ! BMP signaling pathway GO:0030509 71 32 0,000 0,13995373 0,15836357 ! positive regulation of lymphocyte differentiation GO:0045621 56 32 0,000 0,13995373 0,15829026 ! gene silencing GO:0016458 71 32 0,000 0,13995373 0,15821701 ! negative regulation of response to external stimulus GO:0032102 50 33 0,000 0,14399821 0,16271398 ! cholesterol homeostasis GO:0042632 60 33 0,000 0,14399821 0,16263876 GO:0055092|sterol homeostasis, ! pigment biosynthetic process GO:0046148 73 33 0,000 0,14399821 0,1625636 ! unsaturated fatty acid biosynthetic process GO:0006636 65 33 0,000 0,14399821 0,16248851 ! triglyceride metabolic process GO:0006641 46 33 0,000 0,14399821 0,1624135 ! positive regulation of neurogenesis GO:0050769 72 33 0,000 0,14399821 0,16233855 ! pyridine nucleotide metabolic process GO:0019362 60 33 0,000 0,14399821 0,16226367 ! regulation of calcium ion transport GO:0051924 60 33 0,000 0,14399821 0,16218886 ! establishment of vesicle localization GO:0051650 67 33 0,000 0,14399821 0,16211412 ! response to hydrogen peroxide GO:0042542 56 34 0,000 0,14802379 0,16656938 ! glial cell differentiation GO:0010001 67 34 0,000 0,14802379 0,16649269 ! post-embryonic development GO:0009791 76 34 0,000 0,14802379 0,16641607 ! inner ear morphogenesis GO:0042472 51 34 0,000 0,14802379 0,16633952 ! cholesterol transport GO:0030301 62 34 0,000 0,14802379 0,16626304 ! GPI anchor biosynthetic process GO:0006506 58 34 0,000 0,14802379 0,16618664 ! spliceosome assembly GO:0000245 75 34 0,000 0,14802379 0,1661103 ! nuclear-transcribed mRNA catabolic process GO:0000956 57 34 0,000 0,14802379 0,16603403 ! regulation of ARF GTPase activity GO:0032312 73 34 0,000 0,14802379 0,16595783 ! formation of primary germ layer GO:0001704 76 34 0,000 0,14802379 0,16588171 ! serine family amino acid metabolic process GO:0009069 56 34 0,000 0,14802379 0,16580565 ! adult locomotory behavior GO:0008344 62 34 0,000 0,14802379 0,16572966 ! mRNA export from nucleus GO:0006406 53 35 0,000 0,15203055 0,17013771 ! negative regulation of secretion GO:0051048 68 35 0,000 0,15203055 0,17005981 ! proteoglycan metabolic process GO:0006029 75 35 0,000 0,15203055 0,16998198 ! membrane docking GO:0022406 69 35 0,000 0,15203055 0,16990422 ! positive regulation of endocytosis GO:0045807 56 35 0,000 0,15203055 0,16982653 ! GPI anchor metabolic process GO:0006505 61 35 0,000 0,15203055 0,16974892 ! mesoderm morphogenesis GO:0048332 80 35 0,000 0,15203055 0,16967137 ! ceramide metabolic process GO:0006672 72 35 0,000 0,15203055 0,1695939 ! telencephalon development GO:0021537 81 35 0,000 0,15203055 0,16951649 ! sterol transport GO:0015918 63 35 0,000 0,15203055 0,16943916 ! biogenic amine biosynthetic process GO:0042401 65 35 0,000 0,15203055 0,16936189 ! vesicle localization GO:0051648 70 35 0,000 0,15203055 0,1692847 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 52 36 0,000 0,15601858 0,17364619 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 54 36 0,000 0,15601858 0,17356712 ! antigen processing and presentation of peptide antigen GO:0048002 68 36 0,000 0,15601858 0,17348811 ! positive regulation of cell development GO:0010720 85 36 0,000 0,15601858 0,17340918 ! protein targeting to membrane GO:0006612 75 36 0,000 0,15601858 0,17333033 ! regulation of proteolysis GO:0030162 77 36 0,000 0,15601858 0,17325154 ! aerobic respiration GO:0009060 56 36 0,000 0,15601858 0,17317282 ! cytokine production GO:0001816 68 36 0,000 0,15601858 0,17309418 ! pyrimidine nucleotide metabolic process GO:0006220 63 36 0,000 0,15601858 0,17301561 ! negative regulation of adenylate cyclase activity GO:0007194 64 37 0,000 0,15998796 0,17733693 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! odontogenesis GO:0042476 74 37 0,000 0,15998796 0,1772565 ! actomyosin structure organization GO:0031032 68 37 0,000 0,15998796 0,17717615 ! maintenance of protein location in cell GO:0032507 89 37 0,000 0,15998796 0,17709587 ! female gonad development GO:0008585 71 37 0,000 0,15998796 0,17701567 ! hormone biosynthetic process GO:0042446 62 37 0,000 0,15998796 0,17693553 ! positive regulation of JAK-STAT cascade GO:0046427 55 38 0,000 0,16393879 0,18122283 ! organic anion transport GO:0015711 82 38 0,000 0,16393879 0,18114087 ! sphingoid metabolic process GO:0046519 78 38 0,000 0,16393879 0,18105898 ! embryonic skeletal system morphogenesis GO:0048704 68 38 0,000 0,16393879 0,18097716 ! neutral lipid metabolic process GO:0006638 54 38 0,000 0,16393879 0,18089542 GO:0006639|acylglycerol metabolic process, ! cyclic nucleotide metabolic process GO:0009187 69 38 0,000 0,16393879 0,18081375 ! spermatid development GO:0007286 69 38 0,000 0,16393879 0,18073216 ! pigment metabolic process GO:0042440 87 38 0,000 0,16393879 0,18065064 ! regulation of metal ion transport GO:0010959 71 39 0,000 0,16787114 0,18490045 ! regulation of lymphocyte mediated immunity GO:0002706 79 39 0,000 0,16787114 0,18481713 ! nucleotide catabolic process GO:0009166 70 39 0,000 0,16787114 0,18473388 ! erythrocyte homeostasis GO:0034101 75 39 0,000 0,16787114 0,1846507 ! isoprenoid metabolic process GO:0006720 70 39 0,000 0,16787114 0,1845676 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 62 40 0,000 0,17178511 0,18878589 GO:0006956|complement activation, ! ER to Golgi vesicle-mediated transport GO:0006888 91 40 0,000 0,17178511 0,18870101 ! development of primary female sexual characteristics GO:0046545 80 40 0,000 0,17178511 0,1886162 GO:0046660|female sex differentiation, ! lipid homeostasis GO:0055088 75 40 0,000 0,17178511 0,18853146 ! mismatch repair GO:0006298 58 40 0,000 0,17178511 0,18844681 ! glycerol ether metabolic process GO:0006662 57 40 0,000 0,17178511 0,18836222 ! Rho protein signal transduction GO:0007266 88 40 0,000 0,17178511 0,18827772 ! RNA export from nucleus GO:0006405 61 41 0,000 0,17568079 0,19246106 ! mRNA catabolic process GO:0006402 79 41 0,000 0,17568079 0,19237479 ! phosphoinositide biosynthetic process GO:0046489 77 41 0,000 0,17568079 0,1922886 ! regulation of hormone secretion GO:0046883 69 41 0,000 0,17568079 0,19220249 ! establishment or maintenance of cell polarity GO:0007163 96 41 0,000 0,17568079 0,19211645 ! cellular amide metabolic process GO:0043603 73 41 0,000 0,17568079 0,1920305 ! gliogenesis GO:0042063 91 41 0,000 0,17568079 0,19194461 ! feeding behavior GO:0007631 69 41 0,000 0,17568079 0,19185881 ! energy coupled proton transport, down electrochemical gradient GO:0015985 75 41 0,000 0,17568079 0,19177308 GO:0015986|ATP synthesis coupled proton transport, ! maintenance of protein location GO:0045185 95 41 0,000 0,17568079 0,19168743 ! spermatid differentiation GO:0048515 73 41 0,000 0,17568079 0,19160186 ! RNA modification GO:0009451 64 41 0,000 0,17568079 0,19151636 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 66 42 0,000 0,17955824 0,19565601 ! ear morphogenesis GO:0042471 64 42 0,000 0,17955824 0,19556878 ! organic ether metabolic process GO:0018904 59 42 0,000 0,17955824 0,19548163 ! ribonucleoside metabolic process GO:0009119 64 42 0,000 0,17955824 0,19539456 ! regulation of leukocyte mediated immunity GO:0002703 84 42 0,000 0,17955824 0,19530756 ! regulation of protein secretion GO:0050708 77 42 0,000 0,17955824 0,19522064 ! transforming growth factor beta receptor signaling pathway GO:0007179 82 43 0,000 0,18341757 0,1993279 ! protein amino acid N-linked glycosylation GO:0006487 71 43 0,000 0,18341757 0,19923927 ! regulation of tube size GO:0035150 76 43 0,000 0,18341757 0,19915072 GO:0050880|regulation of blood vessel size, ! calcium-dependent cell-cell adhesion GO:0016339 56 43 0,000 0,18341757 0,19906225 ! glucose transport GO:0015758 66 43 0,000 0,18341757 0,19897385 ! striated muscle cell differentiation GO:0051146 91 43 0,000 0,18341757 0,19888554 ! monocarboxylic acid transport GO:0015718 93 43 0,000 0,18341757 0,1987973 ! cytoskeleton-dependent intracellular transport GO:0030705 106 43 0,000 0,18341757 0,19870914 ! hormone-mediated signaling GO:0009755 84 43 0,000 0,18341757 0,19862106 ! ion transmembrane transport GO:0034220 79 43 0,000 0,18341757 0,19853306 ! response to reactive oxygen species GO:0000302 75 44 0,000 0,18725885 0,20260113 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 92 44 0,000 0,18725885 0,20251145 ! hexose transport GO:0008645 68 44 0,000 0,18725885 0,20242184 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 105 44 0,000 0,18725885 0,20233231 ! striated muscle contraction GO:0006941 85 44 0,000 0,18725885 0,20224287 ! phagocytosis GO:0006909 105 44 0,000 0,18725885 0,2021535 ! heterocycle biosynthetic process GO:0018130 76 44 0,000 0,18725885 0,20206421 ! receptor-mediated endocytosis GO:0006898 98 45 0,000 0,19108216 0,20609878 ! ATP synthesis coupled electron transport GO:0042773 69 45 0,000 0,19108216 0,20600782 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! keratinocyte differentiation GO:0030216 81 45 0,000 0,19108216 0,20591695 ! biopolymer methylation GO:0043414 91 45 0,000 0,19108216 0,20582616 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 85 45 0,000 0,19108216 0,20573545 ! female gamete generation GO:0007292 71 45 0,000 0,19108216 0,20564481 ! oxidoreduction coenzyme metabolic process GO:0006733 79 45 0,000 0,19108216 0,20555426 ! polyol metabolic process GO:0019751 77 45 0,000 0,19108216 0,20546379 ! developmental growth GO:0048589 88 45 0,000 0,19108216 0,20537339 ! maintenance of location in cell GO:0051651 101 45 0,000 0,19108216 0,20528308 ! activation of adenylate cyclase activity GO:0007190 94 46 0,000 0,1948876 0,2092793 ! regulation of actin filament polymerization GO:0030833 99 46 0,000 0,1948876 0,20918735 ! glycolysis GO:0006096 71 46 0,000 0,1948876 0,20909548 ! negative regulation of cell migration GO:0030336 122 46 0,000 0,1948876 0,20900369 ! polysaccharide biosynthetic process GO:0000271 79 46 0,000 0,1948876 0,20891198 ! regulation of JNK cascade GO:0046328 104 47 0,000 0,19867525 0,21287878 ! positive regulation of adenylate cyclase activity GO:0045762 104 48 0,000 0,20244518 0,21682313 ! regulation of JAK-STAT cascade GO:0046425 76 48 0,000 0,20244518 0,21672812 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 108 48 0,000 0,20244518 0,21663319 ! endosome transport GO:0016197 127 48 0,000 0,20244518 0,21653834 ! icosanoid metabolic process GO:0006690 92 48 0,000 0,20244518 0,21644357 ! regulation of adaptive immune response GO:0002819 92 48 0,000 0,20244518 0,21634889 ! methylation GO:0032259 97 48 0,000 0,20244518 0,21625429 ! response to calcium ion GO:0051592 94 49 0,000 0,20619748 0,22016627 ! detection of stimulus involved in sensory perception GO:0050906 75 49 0,000 0,20619748 0,22007009 ! positive regulation of cyclase activity GO:0031281 106 49 0,000 0,20619748 0,21997399 ! JNK cascade GO:0007254 106 49 0,000 0,20619748 0,21987797 ! protein homooligomerization GO:0051260 84 49 0,000 0,20619748 0,21978204 ! regulation of ion transport GO:0043269 86 50 0,000 0,20993223 0,22366526 ! endocrine system development GO:0035270 109 50 0,000 0,20993223 0,22356776 ! regulation of ARF protein signal transduction GO:0032012 115 50 0,000 0,20993223 0,22347034 ! regulation of ossification GO:0030278 123 50 0,000 0,20993223 0,22337301 ! immunoglobulin mediated immune response GO:0016064 89 50 0,000 0,20993223 0,22327577 GO:0019724|B cell mediated immunity, ! regulation of gene expression, epigenetic GO:0040029 116 50 0,000 0,20993223 0,22317861 ! positive regulation of lyase activity GO:0051349 107 50 0,000 0,20993223 0,22308153 ! epidermal cell differentiation GO:0009913 87 50 0,000 0,20993223 0,22298454 ! viral infectious cycle GO:0019058 104 51 0,000 0,21364951 0,22683432 ! stress-activated protein kinase signaling pathway GO:0031098 113 51 0,000 0,21364951 0,22673578 ! peptide metabolic process GO:0006518 80 51 0,000 0,21364951 0,22663733 ! detection of abiotic stimulus GO:0009582 80 51 0,000 0,21364951 0,22653896 ! response to estrogen stimulus GO:0043627 98 52 0,000 0,21734941 0,23036209 ! cellular amino acid biosynthetic process GO:0008652 80 52 0,000 0,21734941 0,23026219 ! unsaturated fatty acid metabolic process GO:0033559 98 52 0,000 0,21734941 0,23016238 ! excretion GO:0007588 87 52 0,000 0,21734941 0,23006266 ! DNA-dependent DNA replication GO:0006261 82 52 0,000 0,21734941 0,22996302 ! RNA elongation from RNA polymerase II promoter GO:0006368 82 52 0,000 0,21734941 0,22986347 ! ribonucleoprotein complex assembly GO:0022618 104 52 0,000 0,21734941 0,22976401 ! amino acid activation GO:0043038 98 52 0,000 0,21734941 0,22966463 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! respiratory electron transport chain GO:0022904 83 53 0,000 0,22103201 0,23345491 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 90 53 0,000 0,22103201 0,23335402 ! vesicle organization GO:0016050 127 53 0,000 0,22103201 0,23325322 ! protein amino acid lipidation GO:0006497 109 54 0,000 0,22469738 0,23701887 ! neuromuscular process GO:0050905 107 54 0,000 0,22469738 0,23691657 ! embryonic skeletal system development GO:0048706 101 54 0,000 0,22469738 0,23681436 ! generation of a signal involved in cell-cell signaling GO:0003001 107 54 0,000 0,22469738 0,23671224 ! glutamine family amino acid metabolic process GO:0009064 85 54 0,000 0,22469738 0,23661021 ! RNA catabolic process GO:0006401 103 55 0,000 0,2283456 0,24034826 ! nucleoside monophosphate biosynthetic process GO:0009124 91 55 0,000 0,2283456 0,24024475 ! regulation of actin polymerization or depolymerization GO:0008064 111 55 0,000 0,2283456 0,24014133 ! regulation of multicellular organism growth GO:0040014 90 55 0,000 0,2283456 0,240038 ! cell maturation GO:0048469 107 55 0,000 0,2283456 0,23993476 ! regulation of protein polymerization GO:0032271 117 55 0,000 0,2283456 0,2398316 ! negative regulation of cell motion GO:0051271 142 55 0,000 0,2283456 0,23972854 ! glucose catabolic process GO:0006007 88 56 0,000 0,23197677 0,2434361 ! RNA elongation GO:0006354 90 56 0,000 0,23197677 0,24333158 ! chloride transport GO:0006821 102 57 0,000 0,23559094 0,2470166 ! regulation of actin filament length GO:0030832 118 58 0,000 0,23918821 0,25068074 ! sulfur compound biosynthetic process GO:0044272 108 58 0,000 0,23918821 0,25057324 ! lipoprotein biosynthetic process GO:0042158 115 58 0,000 0,23918821 0,25046584 ! gastrulation GO:0007369 122 58 0,000 0,23918821 0,25035853 ! cellular amino acid derivative biosynthetic process GO:0042398 100 58 0,000 0,23918821 0,25025131 ! maintenance of location GO:0051235 124 58 0,000 0,23918821 0,25014418 ! nuclear export GO:0051168 110 59 0,000 0,24276865 0,25377998 ! regulation of neurotransmitter levels GO:0001505 113 60 0,000 0,24633235 0,25739518 ! lipid modification GO:0030258 112 60 0,000 0,24633235 0,25728513 ! regulation of endocytosis GO:0030100 104 60 0,000 0,24633235 0,25717518 ! heterocycle catabolic process GO:0046700 100 60 0,000 0,24633235 0,25706532 ! adult behavior GO:0030534 104 60 0,000 0,24633235 0,25695556 ! positive regulation of secretion GO:0051047 110 61 0,000 0,24987937 0,2605443 ! regulation of cellular component size GO:0032535 125 61 0,000 0,24987937 0,26043315 ! regulation of Rab protein signal transduction GO:0032483 109 61 0,000 0,24987937 0,26032209 GO:0032313|regulation of Rab GTPase activity, ! glycosaminoglycan metabolic process GO:0030203 108 61 0,000 0,24987937 0,26021112 ! cytokine-mediated signaling pathway GO:0019221 112 61 0,000 0,24987937 0,26010025 ! proton transport GO:0015992 117 61 0,000 0,24987937 0,25998948 ! nucleoside metabolic process GO:0009116 91 62 0,000 0,25340979 0,2635505 ! tRNA processing GO:0008033 102 62 0,000 0,25340979 0,26343835 ! regulation of protein complex assembly GO:0043254 132 63 0,000 0,25692371 0,26697772 ! mesoderm development GO:0007498 128 63 0,000 0,25692371 0,26686421 ! water-soluble vitamin metabolic process GO:0006767 107 63 0,000 0,25692371 0,26675079 ! hydrogen transport GO:0006818 121 64 0,000 0,26042118 0,27026718 ! glycerophospholipid biosynthetic process GO:0046474 116 64 0,000 0,26042118 0,27015241 ! oxygen and reactive oxygen species metabolic process GO:0006800 99 65 0,000 0,26390228 0,2736474 ! lymphocyte mediated immunity GO:0002449 122 65 0,000 0,26390228 0,2735313 ! multicellular organism reproduction GO:0032504 123 65 0,000 0,26390228 0,2734153 GO:0048609|reproductive process in a multicellular organism, ! nucleoside monophosphate metabolic process GO:0009123 117 65 0,000 0,26390228 0,2732994 ! sphingolipid metabolic process GO:0006665 122 65 0,000 0,26390228 0,27318359 ! regulation of lipid metabolic process GO:0019216 132 66 0,000 0,2673671 0,27665304 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 113 67 0,000 0,27081571 0,28010278 ! fatty acid biosynthetic process GO:0006633 139 67 0,000 0,27081571 0,27998425 ! secondary metabolic process GO:0019748 125 67 0,000 0,27081571 0,27986581 ! regulation of cellular response to stress GO:0080135 142 68 0,000 0,27424818 0,28329315 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 116 68 0,000 0,27424818 0,28317342 ! hexose catabolic process GO:0019320 113 68 0,000 0,27424818 0,28305378 ! extracellular matrix organization GO:0030198 146 68 0,000 0,27424818 0,28293425 ! detection of external stimulus GO:0009581 102 68 0,000 0,27424818 0,28281482 ! positive regulation of T cell activation GO:0050870 124 68 0,000 0,27424818 0,28269549 ! cellular hormone metabolic process GO:0034754 120 69 0,000 0,27766459 0,28609641 ! homeostasis of number of cells GO:0048872 131 69 0,000 0,27766459 0,2859758 ! developmental maturation GO:0021700 128 69 0,000 0,27766459 0,28585529 ! activation of immune response GO:0002253 120 70 0,000 0,28106501 0,28923413 ! protein maturation by peptide bond cleavage GO:0051605 118 70 0,000 0,28106501 0,28911235 ! aminoglycan metabolic process GO:0006022 121 71 0,000 0,28444952 0,29247062 ! cAMP-mediated signaling GO:0019933 124 71 0,000 0,28444952 0,29234758 ! carbohydrate transport GO:0008643 114 72 0,000 0,2878182 0,29568539 ! actin filament organization GO:0007015 167 72 0,000 0,2878182 0,2955611 ! coenzyme biosynthetic process GO:0009108 119 72 0,000 0,2878182 0,29543691 ! membrane lipid metabolic process GO:0006643 132 72 0,000 0,2878182 0,29531283 ! regulation of MAPKKK cascade GO:0043408 157 72 0,000 0,2878182 0,29518886 ! humoral immune response GO:0006959 115 73 0,000 0,2911711 0,29850231 ! glycerolipid biosynthetic process GO:0045017 130 73 0,000 0,2911711 0,2983771 ! regulation of immune effector process GO:0002697 156 73 0,000 0,2911711 0,298252 ! acute inflammatory response GO:0002526 118 74 0,000 0,29450832 0,30154394 ! transition metal ion transport GO:0000041 143 75 0,000 0,29782992 0,30481713 ! leukocyte mediated immunity GO:0002443 136 75 0,000 0,29782992 0,30468949 ! regulation of actin cytoskeleton organization GO:0032956 167 76 0,000 0,30113597 0,30794273 ! elevation of cytosolic calcium ion concentration GO:0007204 147 76 0,000 0,30113597 0,30781388 ! regulation of blood pressure GO:0008217 134 76 0,000 0,30113597 0,30768515 ! neurotransmitter transport GO:0006836 142 77 0,000 0,30442655 0,31091725 ! phosphoinositide metabolic process GO:0030384 146 77 0,000 0,30442655 0,31078733 ! cytosolic calcium ion homeostasis GO:0051480 149 77 0,000 0,30442655 0,31065751 ! regulation of vesicle-mediated transport GO:0060627 136 77 0,000 0,30442655 0,3105278 ! monosaccharide catabolic process GO:0046365 125 77 0,000 0,30442655 0,31039819 ! lipoprotein metabolic process GO:0042157 147 78 0,000 0,30770173 0,31360673 ! antigen processing and presentation GO:0019882 117 78 0,000 0,30770173 0,31347595 ! regulation of actin filament-based process GO:0032970 170 79 0,000 0,31096158 0,31666492 ! steroid biosynthetic process GO:0006694 146 79 0,000 0,31096158 0,31653298 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 169 80 0,000 0,31420617 0,31970249 ! activation of protein kinase activity GO:0032147 170 80 0,000 0,31420617 0,31956939 ! muscle cell differentiation GO:0042692 178 81 0,000 0,31743558 0,32271956 ! transcription initiation from RNA polymerase II promoter GO:0006367 136 81 0,000 0,31743558 0,32258532 ! regulation of adenylate cyclase activity GO:0045761 165 83 0,000 0,3238491 0,32896605 ! exocytosis GO:0006887 153 83 0,000 0,3238491 0,32882933 ! cellular lipid catabolic process GO:0044242 150 83 0,000 0,3238491 0,32869271 ! intracellular protein transmembrane transport GO:0065002 165 83 0,000 0,3238491 0,32855621 ! inorganic anion transport GO:0015698 156 83 0,000 0,3238491 0,32841983 ! response to nutrient GO:0007584 135 84 0,000 0,32703337 0,33151142 ! digestion GO:0007586 130 84 0,000 0,32703337 0,33137392 ! cholesterol metabolic process GO:0008203 148 85 0,000 0,33020273 0,33444663 ! regulation of cyclase activity GO:0031279 168 85 0,000 0,33020273 0,33430802 ! regulation of cAMP biosynthetic process GO:0030817 173 86 0,000 0,33335725 0,33736195 ! regulation of lyase activity GO:0051339 169 86 0,000 0,33335725 0,33722226 ! neuropeptide signaling pathway GO:0007218 125 87 0,000 0,336497 0,34025752 ! alcohol catabolic process GO:0046164 142 87 0,000 0,336497 0,34011674 ! nucleosome assembly GO:0006334 126 87 0,000 0,336497 0,33997608 ! cellular respiration GO:0045333 143 88 0,000 0,33962205 0,3429916 ! amine biosynthetic process GO:0009309 146 88 0,000 0,33962205 0,34284986 ! sensory perception of smell GO:0007608 117 88 0,000 0,33962205 0,34270825 ! chromatin assembly GO:0031497 128 88 0,000 0,33962205 0,34256675 ! one-carbon metabolic process GO:0006730 167 88 0,000 0,33962205 0,34242537 ! regulation of cAMP metabolic process GO:0030814 182 89 0,000 0,34273247 0,34541891 ! cellular defense response GO:0006968 123 89 0,000 0,34273247 0,34527647 ! oxidative phosphorylation GO:0006119 152 90 0,000 0,34582833 0,3482517 ! regulation of nucleotide biosynthetic process GO:0030808 183 91 0,000 0,3489097 0,35120988 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! defense response to bacterium GO:0042742 112 91 0,000 0,3489097 0,35106523 ! protein-DNA complex assembly GO:0065004 134 92 0,000 0,35197663 0,35400532 ! vitamin metabolic process GO:0006766 153 93 0,000 0,35502921 0,35692854 ! female pregnancy GO:0007565 166 94 0,000 0,35806749 0,359835 ! sterol metabolic process GO:0016125 166 94 0,000 0,35806749 0,35968704 ! nucleosome organization GO:0034728 143 95 0,000 0,36109154 0,36257568 ! phospholipid biosynthetic process GO:0008654 188 95 0,000 0,36109154 0,36242672 ! regulation of cyclic nucleotide metabolic process GO:0030799 194 95 0,000 0,36109154 0,36227788 ! ATP biosynthetic process GO:0006754 197 95 0,000 0,36109154 0,36212916 ! cofactor biosynthetic process GO:0051188 161 95 0,000 0,36109154 0,36198057 ! biogenic amine metabolic process GO:0006576 162 97 0,000 0,36709724 0,3678501 ! transcription initiation GO:0006352 171 97 0,000 0,36709724 0,36769928 ! regulation of nucleotide metabolic process GO:0006140 197 98 0,000 0,370079 0,37053402 ! mRNA transport GO:0051028 185 100 0,000 0,37600071 0,37630879 ! positive regulation of immune response GO:0050778 175 100 0,000 0,37600071 0,37615469 ! hormone metabolic process GO:0042445 171 100 0,000 0,37600071 0,37600071