pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6418-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! induction of positive chemotaxis GO:0050930 14 8 3,000 9,931E-09 2,284E-05 ! regulation of positive chemotaxis GO:0050926 17 11 3,000 4,645E-08 5,341E-05 GO:0050927|positive regulation of positive chemotaxis, ! induction of apoptosis by intracellular signals GO:0008629 67 40 4,000 2,847E-07 2,182E-04 ! protein amino acid autophosphorylation GO:0046777 80 45 4,000 5,214E-07 2,998E-04 ! positive regulation of locomotion GO:0040017 35 20 3,000 6,658E-07 3,063E-04 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! regulation of chemotaxis GO:0050920 36 21 3,000 8,203E-07 3,144E-04 ! regulation of fibroblast proliferation GO:0048145 35 22 3,000 9,999E-07 3,285E-04 ! regulation of behavior GO:0050795 38 22 3,000 9,999E-07 2,875E-04 ! negative regulation of phosphorylation GO:0042326 41 23 3,000 1,207E-06 3,085E-04 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 2,000 1,472E-06 3,385E-04 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 3,000 1,715E-06 3,587E-04 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of protein kinase activity GO:0006469 99 57 4,000 1,73E-06 3,315E-04 ! negative regulation of kinase activity GO:0033673 100 58 4,000 1,888E-06 3,34E-04 ! negative regulation of transferase activity GO:0051348 105 61 4,000 2,431E-06 3,994E-04 ! regulation of protein import into nucleus GO:0042306 53 29 3,000 3,187E-06 4,886E-04 ! protein oligomerization GO:0051259 100 65 4,000 3,339E-06 4,799E-04 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 2,000 3,514E-06 4,755E-04 ! chondrocyte differentiation GO:0002062 17 11 2,000 6,868E-06 8,776E-04 ! negative regulation of glucose import GO:0046325 14 11 2,000 6,868E-06 8,314E-04 GO:0010829|negative regulation of glucose transport, ! regulation of intracellular protein transport GO:0033157 59 35 3,000 6,914E-06 7,952E-04 ! regulation of epithelial cell proliferation GO:0050678 71 39 3,000 1,075E-05 1,177E-03 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 2,000 1,185E-05 1,238E-03 ! regulation of exocytosis GO:0017157 17 13 2,000 1,185E-05 1,185E-03 ! positive regulation of protein import into nucleus GO:0042307 23 13 2,000 1,185E-05 1,135E-03 ! positive regulation of response to external stimulus GO:0032103 65 40 3,000 1,191E-05 1,096E-03 ! positive regulation of MAP kinase activity GO:0043406 121 85 4,000 1,256E-05 1,111E-03 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 3,000 1,451E-05 1,236E-03 ! regulation of the force of heart contraction GO:0002026 21 15 2,000 1,875E-05 1,54E-03 ! response to UV GO:0009411 75 46 3,000 2,093E-05 1,66E-03 ! neutrophil chemotaxis GO:0030593 21 16 2,000 2,302E-05 1,765E-03 ! regulation of intracellular transport GO:0032386 78 49 3,000 2,696E-05 2E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 2,000 2,788E-05 2,004E-03 ! inactivation of MAPK activity GO:0000188 27 17 2,000 2,788E-05 1,943E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 2,000 2,788E-05 1,886E-03 ! positive regulation of cell migration GO:0030335 92 51 3,000 3,163E-05 2,079E-03 ! regulation of glucose import GO:0046324 21 18 2,000 3,337E-05 2,132E-03 GO:0010827|regulation of glucose transport, ! positive regulation of fibroblast proliferation GO:0048146 27 19 2,000 3,953E-05 2,457E-03 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 2,000 3,953E-05 2,392E-03 ! positive regulation of intracellular transport GO:0032388 29 19 2,000 3,953E-05 2,331E-03 ! positive regulation of cell motion GO:0051272 99 56 3,000 4,588E-05 2,638E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 2,000 4,639E-05 2,602E-03 ! positive regulation of inflammatory response GO:0050729 30 20 2,000 4,639E-05 2,54E-03 ! cellular response to extracellular stimulus GO:0031668 32 21 2,000 5,398E-05 2,887E-03 ! lung development GO:0030324 94 59 3,000 5,64E-05 2,948E-03 ! protein import into nucleus, translocation GO:0000060 36 22 2,000 6,235E-05 3,187E-03 ! protein tetramerization GO:0051262 39 22 2,000 6,235E-05 3,117E-03 ! respiratory tube development GO:0030323 99 62 3,000 6,858E-05 3,356E-03 ! positive regulation of cell adhesion GO:0045785 37 23 2,000 7,152E-05 3,427E-03 ! myelination GO:0042552 35 23 2,000 7,152E-05 3,357E-03 ! regulation of transcription factor import into nucleus GO:0042990 46 23 2,000 7,152E-05 3,29E-03 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 3,000 7,303E-05 3,294E-03 ! respiratory system development GO:0060541 100 64 3,000 7,77E-05 3,437E-03 ! negative regulation of protein modification process GO:0031400 50 26 2,000 1,042E-04 4,522E-03 ! positive regulation of phosphorylation GO:0042327 102 70 3,000 1,104E-04 4,7E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 1,229E-04 5,14E-03 ! forebrain regionalization GO:0021871 6 5 1,000 1,229E-04 5,048E-03 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 1,229E-04 4,959E-03 ! cerebral cortex radially oriented cell migration GO:0021799 8 5 1,000 1,229E-04 4,874E-03 ! positive regulation of glycolysis GO:0045821 11 5 1,000 1,229E-04 4,791E-03 ! microvillus organization GO:0032528 7 5 1,000 1,229E-04 4,711E-03 GO:0030033|microvillus assembly, ! cranial nerve morphogenesis GO:0021602 6 5 1,000 1,229E-04 4,634E-03 ! regulation of respiratory burst GO:0060263 8 5 1,000 1,229E-04 4,559E-03 ! negative regulation of osteoblast differentiation GO:0045668 5 5 1,000 1,229E-04 4,487E-03 ! ectodermal gut morphogenesis GO:0048567 5 5 1,000 1,229E-04 4,417E-03 GO:0007439|ectodermal gut development, ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 1,229E-04 4,349E-03 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 1,000 1,229E-04 4,283E-03 GO:0022011|myelination in the peripheral nervous system, ! positive regulation of phosphorus metabolic process GO:0010562 107 72 3,000 1,232E-04 4,228E-03 GO:0045937|positive regulation of phosphate metabolic process, ! negative regulation of transport GO:0051051 116 73 3,000 1,3E-04 4,396E-03 ! negative regulation of MAP kinase activity GO:0043407 54 28 2,000 1,306E-04 4,354E-03 ! ensheathment of neurons GO:0007272 43 28 2,000 1,306E-04 4,292E-03 GO:0008366|axon ensheathment, ! telencephalon development GO:0021537 52 29 2,000 1,453E-04 4,708E-03 ! regulation of protein transport GO:0051223 114 76 3,000 1,52E-04 4,855E-03 GO:0070201|regulation of establishment of protein localization, ! gland development GO:0048732 148 77 3,000 1,599E-04 5,038E-03 ! mammary gland development GO:0030879 57 31 2,000 1,779E-04 5,529E-03 ! leukocyte chemotaxis GO:0030595 43 31 2,000 1,779E-04 5,455E-03 GO:0060326|cell chemotaxis, ! regulation of helicase activity GO:0051095 11 6 1,000 1,839E-04 5,567E-03 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 1,839E-04 5,494E-03 ! mRNA stabilization GO:0048255 15 6 1,000 1,839E-04 5,424E-03 GO:0043489|RNA stabilization, ! spinal cord dorsal/ventral patterning GO:0021513 6 6 1,000 1,839E-04 5,355E-03 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 1,839E-04 5,288E-03 ! ER overload response GO:0006983 7 6 1,000 1,839E-04 5,223E-03 ! male sex determination GO:0030238 9 6 1,000 1,839E-04 5,159E-03 ! astrocyte development GO:0014002 14 6 1,000 1,839E-04 5,097E-03 ! Schwann cell development GO:0014044 14 6 1,000 1,839E-04 5,036E-03 ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 1,839E-04 4,977E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 1,000 1,839E-04 4,919E-03 ! peripheral nervous system development GO:0007422 53 32 2,000 1,958E-04 5,176E-03 ! regulation of protein localization GO:0032880 132 85 3,000 2,342E-04 6,122E-03 ! dorsal/ventral pattern formation GO:0009953 44 34 2,000 2,35E-04 6,074E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 3,000 2,45E-04 6,261E-03 ! regulation of action potential in neuron GO:0019228 54 35 2,000 2,564E-04 6,481E-03 ! protein homooligomerization GO:0051260 52 35 2,000 2,564E-04 6,41E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 1,000 2,569E-04 6,354E-03 ! cerebral cortex cell migration GO:0021795 11 7 1,000 2,569E-04 6,287E-03 ! T-helper 1 type immune response GO:0042088 11 7 1,000 2,569E-04 6,22E-03 ! spinal cord patterning GO:0021511 7 7 1,000 2,569E-04 6,156E-03 ! protein heterooligomerization GO:0051291 10 7 1,000 2,569E-04 6,092E-03 ! G1 DNA damage checkpoint GO:0031571 18 7 1,000 2,569E-04 6,03E-03 ! B cell lineage commitment GO:0002326 17 7 1,000 2,569E-04 5,969E-03 ! spinal cord motor neuron differentiation GO:0021522 9 7 1,000 2,569E-04 5,909E-03 ! T cell lineage commitment GO:0002360 12 7 1,000 2,569E-04 5,851E-03 ! response to tumor cell GO:0002347 12 7 1,000 2,569E-04 5,793E-03 ! interphase GO:0051325 159 88 3,000 2,676E-04 5,976E-03 ! neural tube development GO:0021915 50 36 2,000 2,79E-04 6,17E-03 ! gliogenesis GO:0042063 71 38 2,000 3,28E-04 7,185E-03 ! peptidyl-amino acid modification GO:0018193 147 93 3,000 3,307E-04 7,175E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 1,000 3,418E-04 7,347E-03 ! cell proliferation in forebrain GO:0021846 10 8 1,000 3,418E-04 7,279E-03 ! positive regulation of B cell proliferation GO:0030890 11 8 1,000 3,418E-04 7,212E-03 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 3,418E-04 7,146E-03 ! smoothened signaling pathway GO:0007224 8 8 1,000 3,418E-04 7,082E-03 ! astrocyte differentiation GO:0048708 16 8 1,000 3,418E-04 7,019E-03 ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 3,418E-04 6,957E-03 ! regulation of vascular permeability GO:0043114 12 8 1,000 3,418E-04 6,896E-03 ! Schwann cell differentiation GO:0014037 17 8 1,000 3,418E-04 6,836E-03 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 1,000 3,418E-04 6,777E-03 ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 3,418E-04 6,719E-03 ! regulation of embryonic development GO:0045995 16 8 1,000 3,418E-04 6,662E-03 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 3,418E-04 6,606E-03 ! regulation of response to external stimulus GO:0032101 139 96 3,000 3,733E-04 7,154E-03 ! response to light stimulus GO:0009416 153 96 3,000 3,733E-04 7,095E-03 ! T cell differentiation GO:0030217 65 40 2,000 3,822E-04 7,205E-03 ! positive regulation of protein transport GO:0051222 55 40 2,000 3,822E-04 7,147E-03 ! regulation of developmental growth GO:0048638 13 9 1,000 4,384E-04 8,132E-03 ! positive regulation of glucose metabolic process GO:0010907 15 9 1,000 4,384E-04 8,067E-03 ! telencephalon cell migration GO:0022029 16 9 1,000 4,384E-04 8,003E-03 ! regulation of glycolysis GO:0006110 15 9 1,000 4,384E-04 7,94E-03 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 1,000 4,384E-04 7,878E-03 ! lung alveolus development GO:0048286 17 9 1,000 4,384E-04 7,817E-03 ! negative regulation of striated muscle development GO:0045843 11 9 1,000 4,384E-04 7,757E-03 ! ventral spinal cord development GO:0021517 11 9 1,000 4,384E-04 7,698E-03 ! motor axon guidance GO:0008045 14 9 1,000 4,384E-04 7,639E-03 ! detection of calcium ion GO:0005513 13 9 1,000 4,384E-04 7,582E-03 ! localization within membrane GO:0051668 15 9 1,000 4,384E-04 7,525E-03 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 4,738E-04 8,072E-03 ! regulation of gene-specific transcription GO:0032583 69 43 2,000 4,738E-04 8,013E-03 ! leukocyte migration GO:0050900 60 43 2,000 4,738E-04 7,954E-03 ! epithelial tube morphogenesis GO:0060562 65 43 2,000 4,738E-04 7,897E-03 ! regulation of action potential GO:0001508 71 44 2,000 5,072E-04 8,392E-03 ! induction of apoptosis by extracellular signals GO:0008624 74 44 2,000 5,072E-04 8,332E-03 ! regulation of inflammatory response GO:0050727 60 44 2,000 5,072E-04 8,273E-03 ! regulation of mast cell proliferation GO:0070666 64 44 2,000 5,072E-04 8,215E-03 ! positive regulation of defense response GO:0031349 59 45 2,000 5,42E-04 8,718E-03 ! negative regulation of muscle development GO:0048635 12 10 1,000 5,468E-04 8,734E-03 ! neuron fate specification GO:0048665 11 10 1,000 5,468E-04 8,673E-03 ! regulation of B cell proliferation GO:0030888 15 10 1,000 5,468E-04 8,614E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 1,000 5,468E-04 8,555E-03 ! blood vessel remodeling GO:0001974 21 10 1,000 5,468E-04 8,497E-03 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 5,468E-04 8,44E-03 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 5,468E-04 8,384E-03 ! response to X-ray GO:0010165 16 10 1,000 5,468E-04 8,329E-03 ! forebrain cell migration GO:0021885 17 10 1,000 5,468E-04 8,274E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 1,000 5,468E-04 8,22E-03 ! regulation of bone resorption GO:0045124 24 10 1,000 5,468E-04 8,166E-03 ! cranial nerve development GO:0021545 12 10 1,000 5,468E-04 8,114E-03 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 5,468E-04 8,062E-03 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 1,000 5,468E-04 8,01E-03 GO:0043470|regulation of carbohydrate catabolic process, ! embryonic gut development GO:0048566 11 10 1,000 5,468E-04 7,96E-03 ! cytoplasmic sequestering of protein GO:0051220 14 10 1,000 5,468E-04 7,91E-03 ! regulation of leukocyte proliferation GO:0070663 71 47 2,000 6,163E-04 8,859E-03 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! regulation of muscle contraction GO:0006937 69 48 2,000 6,557E-04 9,367E-03 ! regulation of DNA replication GO:0006275 75 48 2,000 6,557E-04 9,31E-03 ! virus-host interaction GO:0019048 17 11 1,000 6,668E-04 9,409E-03 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 1,000 6,668E-04 9,351E-03 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 6,668E-04 9,294E-03 ! regulation of intracellular pH GO:0051453 17 11 1,000 6,668E-04 9,238E-03 ! nitric oxide metabolic process GO:0046209 14 11 1,000 6,668E-04 9,183E-03 GO:0006809|nitric oxide biosynthetic process, ! regulation of leukocyte migration GO:0002685 24 11 1,000 6,668E-04 9,129E-03 ! digestive tract morphogenesis GO:0048546 15 11 1,000 6,668E-04 9,074E-03 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! negative regulation of mast cell proliferation GO:0070667 17 11 1,000 6,668E-04 9,021E-03 GO:0042130|negative regulation of T cell proliferation, ! cartilage development GO:0051216 70 49 2,000 6,967E-04 9,371E-03 ! positive regulation of growth GO:0045927 67 50 2,000 7,393E-04 9,886E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 2,000 7,836E-04 0,01041731 ! positive regulation of cellular catabolic process GO:0031331 22 12 1,000 7,983E-04 0,01055232 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 1,000 7,983E-04 0,01049203 ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 1,000 7,983E-04 0,01043241 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! histone acetylation GO:0016573 23 12 1,000 7,983E-04 0,01037347 ! peptidyl-lysine modification GO:0018205 18 12 1,000 7,983E-04 0,01031519 ! response to gamma radiation GO:0010332 20 12 1,000 7,983E-04 0,01025757 ! regulation of mRNA stability GO:0043488 27 12 1,000 7,983E-04 0,01020058 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 7,983E-04 0,01014422 ! regulation of bone remodeling GO:0046850 90 53 2,000 8,77E-04 0,01108294 ! regulation of tissue remodeling GO:0034103 91 54 2,000 9,263E-04 0,0116414 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 9,413E-04 0,01176624 ! cell differentiation in spinal cord GO:0021515 16 13 1,000 9,413E-04 0,01170264 ! negative regulation of protein import into nucleus GO:0042308 25 13 1,000 9,413E-04 0,01163972 ! regulation of cellular pH GO:0030641 20 13 1,000 9,413E-04 0,01157748 ! regulation of monooxygenase activity GO:0032768 26 13 1,000 9,413E-04 0,01151589 ! regulation of RNA stability GO:0043487 28 13 1,000 9,413E-04 0,01145496 ! negative regulation of response to stimulus GO:0048585 80 56 2,000 1,03E-03 0,01246771 ! G1 phase of mitotic cell cycle GO:0000080 23 14 1,000 1,096E-03 0,01319401 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 1,096E-03 0,01312529 ! limbic system development GO:0021761 25 14 1,000 1,096E-03 0,01305728 ! pituitary gland development GO:0021983 23 14 1,000 1,096E-03 0,01298998 ! cellular response to starvation GO:0009267 21 14 1,000 1,096E-03 0,01292336 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 1,000 1,096E-03 0,01285742 GO:0060675|ureteric bud morphogenesis, ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 1,096E-03 0,01279216 ! G1/S transition checkpoint GO:0031575 33 14 1,000 1,096E-03 0,01272755 ! synaptic transmission, cholinergic GO:0007271 21 14 1,000 1,096E-03 0,01266359 ! regulation of erythrocyte differentiation GO:0045646 27 14 1,000 1,096E-03 0,01260028 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 1,096E-03 0,01253759 ! epithelial to mesenchymal transition GO:0001837 22 14 1,000 1,096E-03 0,01247552 ! activation of MAPK activity GO:0000187 84 59 2,000 1,199E-03 0,01358235 ! embryonic limb morphogenesis GO:0030326 86 60 2,000 1,259E-03 0,01419136 GO:0035113|embryonic appendage morphogenesis, ! regulation of heart contraction GO:0008016 91 60 2,000 1,259E-03 0,01412214 ! regulation of vesicle-mediated transport GO:0060627 79 60 2,000 1,259E-03 0,01405358 ! regulation of homeostatic process GO:0032844 105 60 2,000 1,259E-03 0,01398569 ! embryonic forelimb morphogenesis GO:0035115 17 15 1,000 1,261E-03 0,0139477 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 1,000 1,261E-03 0,01388097 ! cerebral cortex development GO:0021987 29 15 1,000 1,261E-03 0,01381487 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 1,261E-03 0,01374939 ! negative regulation of leukocyte proliferation GO:0070664 25 15 1,000 1,261E-03 0,01368454 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 1,261E-03 0,01362029 ! negative regulation of cell growth GO:0030308 106 62 2,000 1,384E-03 0,01487635 ! regulation of glucose metabolic process GO:0010906 22 16 1,000 1,438E-03 0,01538607 ! protein amino acid acetylation GO:0006473 28 16 1,000 1,438E-03 0,01531484 ! glial cell development GO:0021782 24 16 1,000 1,438E-03 0,01524426 ! diencephalon development GO:0021536 25 16 1,000 1,438E-03 0,01517433 ! G1 phase GO:0051318 27 16 1,000 1,438E-03 0,01510504 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 1,000 1,438E-03 0,01503639 ! nerve development GO:0021675 18 16 1,000 1,438E-03 0,01496835 ! negative regulation of cell size GO:0045792 108 64 2,000 1,517E-03 0,01571852 ! appendage morphogenesis GO:0035107 93 64 2,000 1,517E-03 0,01564803 GO:0035108|limb morphogenesis, ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 2,000 1,517E-03 0,01557818 ! regulation of caspase activity GO:0043281 97 65 2,000 1,587E-03 0,01621853 ! appendage development GO:0048736 94 65 2,000 1,587E-03 0,01614677 GO:0060173|limb development, ! forelimb morphogenesis GO:0035136 19 17 1,000 1,626E-03 0,01647807 ! neuromuscular junction development GO:0007528 23 17 1,000 1,626E-03 0,0164058 ! negative regulation of intracellular transport GO:0032387 29 17 1,000 1,626E-03 0,01633416 ! proximal/distal pattern formation GO:0009954 25 17 1,000 1,626E-03 0,01626314 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 1,626E-03 0,01619274 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 1,731E-03 0,01716406 ! positive regulation of DNA replication GO:0045740 29 18 1,000 1,825E-03 0,01801929 ! axis specification GO:0009798 26 18 1,000 1,825E-03 0,01794228 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 1,825E-03 0,01786593 ! somitogenesis GO:0001756 24 18 1,000 1,825E-03 0,01779023 ! detection of chemical stimulus GO:0009593 26 18 1,000 1,825E-03 0,01771516 ! cellular response to nutrient levels GO:0031669 27 18 1,000 1,825E-03 0,01764073 ! activation of JUN kinase activity GO:0007257 23 18 1,000 1,825E-03 0,01756692 ! gut development GO:0048565 26 18 1,000 1,825E-03 0,01749372 ! negative regulation of T cell activation GO:0050868 25 18 1,000 1,825E-03 0,01742114 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 1,825E-03 0,01734915 ! regulation of carbohydrate metabolic process GO:0006109 28 19 1,000 2,036E-03 0,01926641 GO:0010675|regulation of cellular carbohydrate metabolic process, ! negative regulation of epithelial cell proliferation GO:0050680 34 19 1,000 2,036E-03 0,01918745 ! response to starvation GO:0042594 30 19 1,000 2,036E-03 0,01910914 ! sex determination GO:0007530 29 19 1,000 2,036E-03 0,01903146 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 2,036E-03 0,01895441 ! embryonic organ morphogenesis GO:0048562 23 19 1,000 2,036E-03 0,01887798 ! lymphocyte differentiation GO:0030098 113 71 2,000 2,045E-03 0,01888929 ! regulation of peptidase activity GO:0052547 106 72 2,000 2,129E-03 0,01958245 ! response to hypoxia GO:0001666 132 72 2,000 2,129E-03 0,01950443 ! tube morphogenesis GO:0035239 118 73 2,000 2,214E-03 0,02020878 ! hindlimb morphogenesis GO:0035137 32 20 1,000 2,257E-03 0,02051414 ! spinal cord development GO:0021510 31 20 1,000 2,257E-03 0,02043338 ! pallium development GO:0021543 38 20 1,000 2,257E-03 0,02035324 ! positive regulation of B cell activation GO:0050871 31 20 1,000 2,257E-03 0,02027374 ! camera-type eye morphogenesis GO:0048593 34 20 1,000 2,257E-03 0,02019485 ! response to oxygen levels GO:0070482 137 74 2,000 2,302E-03 0,02052123 ! protein import into nucleus GO:0006606 118 74 2,000 2,302E-03 0,020442 ! negative regulation of growth GO:0045926 123 75 2,000 2,392E-03 0,02115864 ! nuclear import GO:0051170 121 75 2,000 2,392E-03 0,02107757 ! regulation of cell morphogenesis GO:0022604 140 76 2,000 2,484E-03 0,02180519 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 1,000 2,488E-03 0,02176172 ! protein amino acid acylation GO:0043543 37 21 1,000 2,488E-03 0,02167929 ! cell aging GO:0007569 32 21 1,000 2,488E-03 0,02159748 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 2,488E-03 0,02151629 ! response to endoplasmic reticulum stress GO:0034976 25 21 1,000 2,488E-03 0,0214357 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 1,000 2,488E-03 0,02135572 ! regulation of DNA binding GO:0051101 119 77 2,000 2,578E-03 0,02204333 ! positive regulation of protein modification process GO:0031401 107 78 2,000 2,675E-03 0,02278289 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 1,000 2,731E-03 0,02317833 ! vasculogenesis GO:0001570 33 22 1,000 2,731E-03 0,02309311 ! regulation of cell-matrix adhesion GO:0001952 51 22 1,000 2,731E-03 0,02300852 GO:0010810|regulation of cell-substrate adhesion, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 1,000 2,731E-03 0,02292455 ! ureteric bud development GO:0001657 32 22 1,000 2,731E-03 0,02284119 ! neural tube closure GO:0001843 33 22 1,000 2,731E-03 0,02275843 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! positive regulation of JUN kinase activity GO:0043507 28 22 1,000 2,731E-03 0,02267627 ! T cell activation GO:0042110 134 79 2,000 2,773E-03 0,02294304 ! protein localization in nucleus GO:0034504 133 80 2,000 2,874E-03 0,02369194 ! forebrain development GO:0030900 131 80 2,000 2,874E-03 0,02360733 ! neuron fate commitment GO:0048663 32 23 1,000 2,984E-03 0,02442663 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 1,000 2,984E-03 0,02434001 ! ER-nuclear signaling pathway GO:0006984 27 23 1,000 2,984E-03 0,024254 ! negative regulation of DNA replication GO:0008156 35 23 1,000 2,984E-03 0,0241686 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 2,984E-03 0,0240838 ! interaction with host GO:0051701 37 23 1,000 2,984E-03 0,02399959 ! regulation of cell adhesion GO:0030155 159 83 2,000 3,19E-03 0,02556341 ! regulation of cellular catabolic process GO:0031329 36 24 1,000 3,248E-03 0,02594037 ! insulin receptor signaling pathway GO:0008286 40 24 1,000 3,248E-03 0,02585061 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 3,248E-03 0,02576147 ! mitochondrial membrane organization GO:0007006 39 24 1,000 3,248E-03 0,02567294 ! response to toxin GO:0009636 38 24 1,000 3,248E-03 0,02558502 ! primary neural tube formation GO:0014020 35 24 1,000 3,248E-03 0,0254977 ! negative regulation of cell development GO:0010721 56 24 1,000 3,248E-03 0,02541097 GO:0050768|negative regulation of neurogenesis, ! base-excision repair GO:0006284 31 24 1,000 3,248E-03 0,02532483 ! regulation of oxidoreductase activity GO:0051341 39 24 1,000 3,248E-03 0,02523928 ! regulation of osteoblast differentiation GO:0045667 37 24 1,000 3,248E-03 0,02515429 ! neurotransmitter secretion GO:0007269 32 24 1,000 3,248E-03 0,02506988 ! regulation of JUN kinase activity GO:0043506 34 24 1,000 3,248E-03 0,02498604 ! regulation of defense response GO:0031347 117 84 2,000 3,3E-03 0,02529789 ! regulation of DNA metabolic process GO:0051052 135 85 2,000 3,412E-03 0,02607082 ! anterior/posterior pattern formation GO:0009952 124 85 2,000 3,412E-03 0,02598449 ! regulation of membrane potential GO:0042391 128 85 2,000 3,412E-03 0,02589874 ! protein amino acid alkylation GO:0008213 39 25 1,000 3,523E-03 0,02665125 GO:0006479|protein amino acid methylation, ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 3,523E-03 0,02656387 ! negative regulation of lymphocyte activation GO:0051250 37 25 1,000 3,523E-03 0,02647706 ! cell cycle arrest GO:0007050 150 86 2,000 3,526E-03 0,02641885 ! skeletal muscle tissue development GO:0007519 123 87 2,000 3,643E-03 0,02720524 GO:0060538|skeletal muscle organ development, ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 3,807E-03 0,02834037 ! regulation of pH GO:0006885 36 26 1,000 3,807E-03 0,02824895 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 3,807E-03 0,02815812 ! regulation of neurogenesis GO:0050767 153 89 2,000 3,884E-03 0,02863032 ! leukocyte differentiation GO:0002521 143 90 2,000 4,008E-03 0,02944904 ! response to ionizing radiation GO:0010212 47 27 1,000 4,103E-03 0,0300517 ! negative regulation of leukocyte activation GO:0002695 39 27 1,000 4,103E-03 0,0299563 ! negative regulation of protein transport GO:0051224 49 27 1,000 4,103E-03 0,0298615 ! cell fate commitment GO:0045165 141 92 2,000 4,263E-03 0,03092687 ! positive regulation of multicellular organism growth GO:0040018 38 28 1,000 4,408E-03 0,03188361 ! neural tube formation GO:0001841 41 28 1,000 4,408E-03 0,03178366 ! positive regulation of catabolic process GO:0009896 40 28 1,000 4,408E-03 0,03168433 ! regulation of B cell activation GO:0050864 42 28 1,000 4,408E-03 0,03158563 ! regulation of binding GO:0051098 151 95 2,000 4,663E-03 0,03330718 ! angiogenesis GO:0001525 149 95 2,000 4,663E-03 0,03320407 ! regulation of axonogenesis GO:0050770 51 29 1,000 4,724E-03 0,03353476 ! eye morphogenesis GO:0048592 51 29 1,000 4,724E-03 0,03343158 ! embryonic skeletal system morphogenesis GO:0048704 42 30 1,000 5,05E-03 0,0356285 ! embryonic epithelial tube formation GO:0001838 44 30 1,000 5,05E-03 0,03551954 ! negative regulation of cell activation GO:0050866 44 30 1,000 5,05E-03 0,03541125 ! protein import GO:0017038 156 99 2,000 5,231E-03 0,03657181 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 2,000 5,231E-03 0,03646099 ! protein localization in organelle GO:0033365 161 100 2,000 5,38E-03 0,03738139 ! DNA damage checkpoint GO:0000077 53 31 1,000 5,386E-03 0,03731235 ! glial cell differentiation GO:0010001 55 31 1,000 5,386E-03 0,0372003 ! xenobiotic metabolic process GO:0006805 44 31 1,000 5,386E-03 0,03708893 ! odontogenesis GO:0042476 50 31 1,000 5,386E-03 0,03697821 ! maintenance of protein location in cell GO:0032507 60 31 1,000 5,386E-03 0,03686816 ! segmentation GO:0035282 41 31 1,000 5,386E-03 0,03675876 ! regulation of striated muscle tissue development GO:0016202 47 31 1,000 5,386E-03 0,03665 ! metanephros development GO:0001656 58 31 1,000 5,386E-03 0,03654189 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 5,386E-03 0,03643442 ! cell fate specification GO:0001708 37 31 1,000 5,386E-03 0,03632757 ! regulation of muscle development GO:0048634 48 32 1,000 5,732E-03 0,03854833 ! negative regulation of DNA metabolic process GO:0051053 48 32 1,000 5,732E-03 0,03843594 ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 5,732E-03 0,03832421 ! calcium-mediated signaling GO:0019722 50 32 1,000 5,732E-03 0,03821312 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 1,000 5,732E-03 0,03810268 ! positive regulation of DNA metabolic process GO:0051054 54 33 1,000 6,088E-03 0,04035216 ! carbohydrate homeostasis GO:0033500 39 33 1,000 6,088E-03 0,04023621 GO:0042593|glucose homeostasis, ! negative regulation of DNA binding GO:0043392 54 33 1,000 6,088E-03 0,04012092 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 6,088E-03 0,04000629 ! androgen receptor signaling pathway GO:0030521 54 33 1,000 6,088E-03 0,03989231 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 6,454E-03 0,04216919 ! regulation of neuron projection development GO:0010975 63 34 1,000 6,454E-03 0,04204973 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 6,454E-03 0,04193094 ! DNA integrity checkpoint GO:0031570 57 34 1,000 6,454E-03 0,04181283 ! neuron migration GO:0001764 46 34 1,000 6,454E-03 0,04169538 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 1,000 6,454E-03 0,04157858 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 6,454E-03 0,04146244 ! embryonic organ development GO:0048568 45 34 1,000 6,454E-03 0,04134695 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 1,000 6,454E-03 0,04123209 ! maintenance of protein location GO:0045185 65 35 1,000 6,829E-03 0,04351086 ! positive regulation of leukocyte proliferation GO:0070665 50 35 1,000 6,829E-03 0,04339067 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 7,215E-03 0,04571251 GO:0090047|positive regulation of transcription regulator activity, ! negative regulation of binding GO:0051100 58 36 1,000 7,215E-03 0,04558692 ! tissue remodeling GO:0048771 62 36 1,000 7,215E-03 0,04546203 ! response to xenobiotic stimulus GO:0009410 50 36 1,000 7,215E-03 0,04533781 ! regulation of T cell proliferation GO:0042129 58 38 1,000 8,014E-03 0,05022471 ! mesenchymal cell development GO:0014031 64 38 1,000 8,014E-03 0,05008823 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! maintenance of location in cell GO:0051651 69 38 1,000 8,014E-03 0,04995249 ! morphogenesis of embryonic epithelium GO:0016331 60 39 1,000 8,428E-03 0,05239123 ! JNK cascade GO:0007254 54 39 1,000 8,428E-03 0,05225001 ! developmental growth GO:0048589 62 39 1,000 8,428E-03 0,05210956 ! synapse organization GO:0050808 55 39 1,000 8,428E-03 0,05196985 ! response to calcium ion GO:0051592 58 40 1,000 8,852E-03 0,05443513 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 1,000 8,852E-03 0,05428997 ! double-strand break repair GO:0006302 67 40 1,000 8,852E-03 0,05414558 ! B cell differentiation GO:0030183 62 40 1,000 8,852E-03 0,05400196 ! regulation of myeloid cell differentiation GO:0045637 69 40 1,000 8,852E-03 0,0538591 ! positive regulation of DNA binding GO:0043388 57 41 1,000 9,284E-03 0,05634369 ! regulation of T cell differentiation GO:0045580 59 41 1,000 9,284E-03 0,05619542 ! biopolymer methylation GO:0043414 62 41 1,000 9,284E-03 0,05604793 ! regulation of JNK cascade GO:0046328 58 41 1,000 9,284E-03 0,0559012 ! mitochondrial transport GO:0006839 60 42 1,000 9,727E-03 0,05841034 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 1,000 9,727E-03 0,05825823 ! branching morphogenesis of a tube GO:0048754 72 42 1,000 9,727E-03 0,05810691 ! embryonic skeletal system development GO:0048706 56 42 1,000 9,727E-03 0,05795637 ! regulation of cell shape GO:0008360 78 42 1,000 9,727E-03 0,05780661 ! positive regulation of binding GO:0051099 59 43 1,000 0,01017795 0,06033319 ! activation of caspase activity GO:0006919 65 43 1,000 0,01017795 0,06017809 ! response to insulin stimulus GO:0032868 63 43 1,000 0,01017795 0,06002379 ! methylation GO:0032259 64 43 1,000 0,01017795 0,05987027 ! regulation of cell projection organization GO:0031344 83 44 1,000 0,01063846 0,06241953 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 1,000 0,01063846 0,0622607 ! positive regulation of cell cycle GO:0045787 77 45 1,000 0,01110806 0,064844 ! vascular process in circulatory system GO:0003018 69 45 1,000 0,01110806 0,06467984 ! regulation of ossification GO:0030278 71 46 1,000 0,01158668 0,06729637 ! histone modification GO:0016570 68 46 1,000 0,01158668 0,06712686 ! endocrine system development GO:0035270 83 47 1,000 0,01207425 0,06977583 ! covalent chromatin modification GO:0016569 75 47 1,000 0,01207425 0,06960096 ! negative regulation of immune system process GO:0002683 73 47 1,000 0,01207425 0,06942695 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,01207425 0,06925382 ! positive regulation of caspase activity GO:0043280 72 48 1,000 0,01257071 0,07192198 GO:0010952|positive regulation of peptidase activity, ! heart morphogenesis GO:0003007 65 48 1,000 0,01257071 0,07174351 ! regulation of lymphocyte differentiation GO:0045619 69 48 1,000 0,01257071 0,07156593 ! regulation of angiogenesis GO:0045765 94 49 1,000 0,01307599 0,07425869 ! morphogenesis of a branching structure GO:0001763 86 49 1,000 0,01307599 0,07407579 ! integrin-mediated signaling pathway GO:0007229 81 49 1,000 0,01307599 0,07389378 ! maintenance of location GO:0051235 84 49 1,000 0,01307599 0,07371267 ! skeletal muscle fiber development GO:0048741 73 50 1,000 0,01359001 0,07642306 ! regulation of multicellular organism growth GO:0040014 65 50 1,000 0,01359001 0,07623666 ! activation of phospholipase C activity GO:0007202 87 51 1,000 0,01411273 0,07897633 GO:0010863|positive regulation of phospholipase C activity, ! muscle fiber development GO:0048747 74 51 1,000 0,01411273 0,07878464 ! positive regulation of phospholipase activity GO:0010518 88 52 1,000 0,01464406 0,08155286 ! aging GO:0007568 79 52 1,000 0,01464406 0,08135588 ! nucleotide-excision repair GO:0006289 64 52 1,000 0,01464406 0,08115984 ! regulation of neurotransmitter levels GO:0001505 73 53 1,000 0,01518394 0,08394968 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,01518394 0,08374836 ! kidney development GO:0001822 90 53 1,000 0,01518394 0,08354801 ! cell projection assembly GO:0030031 76 53 1,000 0,01518394 0,08334861 ! regulation of mitosis GO:0007088 84 54 1,000 0,01573231 0,08615315 GO:0051783|regulation of nuclear division, ! regulation of phospholipase activity GO:0010517 90 54 1,000 0,01573231 0,08594851 ! positive regulation of lipase activity GO:0060193 90 54 1,000 0,01573231 0,08574484 ! DNA damage response, signal transduction GO:0042770 96 56 1,000 0,01685427 0,09164258 ! camera-type eye development GO:0043010 88 57 1,000 0,01742771 0,09453713 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 0,01742771 0,09431469 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,01760919 0,09507311 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,01760919 0,09485046 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,01760919 0,09462884 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,01760919 0,09440826 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,01760919 0,09418871 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01760919 0,09397017 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,01760919 0,09375265 ! benzene and derivative metabolic process GO:0042537 11 5 0,000 0,01760919 0,09353613 ! sleep GO:0030431 11 5 0,000 0,01760919 0,09332061 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,01760919 0,09310608 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,01760919 0,09289253 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,01760919 0,09267997 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 0,000 0,01760919 0,09246837 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 6 5 0,000 0,01760919 0,09225773 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,01760919 0,09204806 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01760919 0,09183933 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,01760919 0,09163155 ! cobalt ion transport GO:0006824 9 5 0,000 0,01760919 0,09142471 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,01760919 0,0912188 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,01760919 0,09101381 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,01760919 0,09080974 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,01760919 0,09060659 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,01760919 0,09040434 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,01760919 0,090203 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,01760919 0,09000254 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,01760919 0,08980298 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,01760919 0,0896043 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01760919 0,0894065 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01760919 0,08920957 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01760919 0,08901351 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,01760919 0,0888183 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01760919 0,08862395 ! malate metabolic process GO:0006108 7 5 0,000 0,01760919 0,08843045 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,01760919 0,08823779 ! behavioral response to pain GO:0048266 7 5 0,000 0,01760919 0,08804597 ! clathrin coat assembly GO:0048268 11 5 0,000 0,01760919 0,08785498 ! phototransduction, visible light GO:0007603 6 5 0,000 0,01760919 0,08766482 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01760919 0,08747548 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! mating behavior GO:0007617 6 5 0,000 0,01760919 0,08728695 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01760919 0,08709924 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,01760919 0,08691233 ! rhythmic behavior GO:0007622 12 5 0,000 0,01760919 0,08672622 ! copulation GO:0007620 7 5 0,000 0,01760919 0,08654091 ! glial cell fate commitment GO:0021781 12 5 0,000 0,01760919 0,08635639 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,01760919 0,08617265 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,01760919 0,08598969 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,01760919 0,08580751 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,01760919 0,0856261 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,01760919 0,08544545 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,01760919 0,08526557 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,01760919 0,08508644 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01760919 0,08490806 ! response to protozoan GO:0001562 9 5 0,000 0,01760919 0,08473043 ! lymph vessel development GO:0001945 7 5 0,000 0,01760919 0,08455354 ! endochondral ossification GO:0001958 12 5 0,000 0,01760919 0,08437739 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,01760919 0,08420197 ! parathyroid gland development GO:0060017 8 5 0,000 0,01760919 0,08402727 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,01760919 0,0838533 ! anagen GO:0042640 6 5 0,000 0,01760919 0,08368005 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,01760919 0,08350752 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,01760919 0,08333569 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,01760919 0,08316457 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,01760919 0,08299415 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,01760919 0,08282443 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,01760919 0,0826554 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,01760919 0,08248706 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,01760919 0,0823194 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,01760919 0,08215242 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 6 5 0,000 0,01760919 0,08198612 ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,01760919 0,0818205 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,01760919 0,08165553 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,01760919 0,08149124 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,01760919 0,0813276 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,01760919 0,08116462 ! ovulation GO:0030728 6 5 0,000 0,01760919 0,08100229 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,01760919 0,08084061 GO:0033135|regulation of peptidyl-serine phosphorylation, ! valine metabolic process GO:0006573 8 5 0,000 0,01760919 0,08067957 ! response to pH GO:0009268 9 5 0,000 0,01760919 0,08051918 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,01760919 0,08035942 ! proline biosynthetic process GO:0006561 6 5 0,000 0,01760919 0,08020029 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01760919 0,08004179 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,01760919 0,07988392 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01760919 0,07972666 ! polyol catabolic process GO:0046174 7 5 0,000 0,01760919 0,07957003 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01760919 0,07941401 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01760919 0,0792586 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01760919 0,0791038 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,01760919 0,0789496 ! nerve growth factor processing GO:0032455 7 5 0,000 0,01760919 0,078796 ! urea metabolic process GO:0019627 6 5 0,000 0,01760919 0,078643 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,01760919 0,07849059 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01760919 0,07833877 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,01760919 0,07818754 ! neutrophil activation GO:0042119 5 5 0,000 0,01760919 0,07803689 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,01760919 0,07788682 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,01760919 0,07773732 ! response to food GO:0032094 5 5 0,000 0,01760919 0,0775884 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,01760919 0,07744005 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01760919 0,07729226 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,01760919 0,07714504 ! forebrain neuron development GO:0021884 7 5 0,000 0,01760919 0,07699837 ! melanosome organization GO:0032438 7 5 0,000 0,01760919 0,07685227 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,01760919 0,07670671 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,01760919 0,07656171 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,01760919 0,07641726 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01760919 0,07627334 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,01760919 0,07612997 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,01760919 0,07598714 ! nucleoside transport GO:0015858 6 5 0,000 0,01760919 0,07584484 ! nucleoside salvage GO:0043174 7 5 0,000 0,01760919 0,07570308 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,01760919 0,07556184 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01760919 0,07542113 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,01760919 0,07528094 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,01760919 0,07514127 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01760919 0,07500212 ! early endosome to late endosome transport GO:0045022 11 5 0,000 0,01760919 0,07486348 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01760919 0,07472536 ! depyrimidination GO:0045008 8 5 0,000 0,01760919 0,07458774 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,01760919 0,07445063 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,01760919 0,07431403 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,01760919 0,07417792 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01760919 0,07404231 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,01760919 0,0739072 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,01760919 0,07377258 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,01760919 0,07363845 ! negative regulation of gliogenesis GO:0014014 16 5 0,000 0,01760919 0,0735048 GO:0045686|negative regulation of glial cell differentiation, ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,01760919 0,07337164 ! monocyte differentiation GO:0030224 8 5 0,000 0,01760919 0,07323896 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,01760919 0,07310676 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01760919 0,07297504 ! centrosome duplication GO:0051298 5 5 0,000 0,01760919 0,07284379 ! response to UV-C GO:0010225 6 5 0,000 0,01760919 0,07271301 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,01760919 0,0725827 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,01760919 0,07245285 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,01760919 0,07232347 ! regulation of dendrite development GO:0050773 12 5 0,000 0,01760919 0,07219455 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,01760919 0,07206609 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01760919 0,07193809 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,01760919 0,07181054 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,01760919 0,07168344 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,01760919 0,07155679 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,01760919 0,07143059 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,01760919 0,07130483 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,01760919 0,07117952 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01760919 0,07105464 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,01760919 0,0709302 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01760919 0,0708062 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01760919 0,07068263 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,01760919 0,07055949 ! neural tube patterning GO:0021532 6 5 0,000 0,01760919 0,07043677 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,01760919 0,07031449 ! histone demethylation GO:0016577 9 5 0,000 0,01760919 0,07019263 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,01760919 0,07007119 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01760919 0,06995016 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,01760919 0,06982956 ! enteric nervous system development GO:0048484 8 5 0,000 0,01760919 0,06970937 ! establishment of planar polarity GO:0001736 6 5 0,000 0,01760919 0,0695896 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,01760919 0,06947023 ! muscle cell proliferation GO:0033002 8 5 0,000 0,01760919 0,06935128 ! transcription termination GO:0006353 8 5 0,000 0,01760919 0,06923273 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,01760919 0,06911458 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,01760919 0,06899684 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,01760919 0,0688795 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,01760919 0,06876256 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01760919 0,06864601 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01760919 0,06852986 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,01760919 0,0684141 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,01760919 0,06829873 ! apical protein localization GO:0045176 6 5 0,000 0,01760919 0,06818375 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,01760919 0,06806915 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01760919 0,06795494 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01760919 0,06784111 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,01760919 0,06772767 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,01760919 0,0676146 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,01760919 0,06750191 ! glial cell migration GO:0008347 10 5 0,000 0,01760919 0,06738959 ! determination of adult lifespan GO:0008340 8 5 0,000 0,01760919 0,06727765 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,01760919 0,06716608 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01760919 0,06705488 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,01760919 0,06694404 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,01760919 0,06683357 ! neural plate development GO:0001840 6 5 0,000 0,01760919 0,06672347 ! regulation of sensory perception GO:0051931 6 5 0,000 0,01760919 0,06661373 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,01760919 0,06650434 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,01760919 0,06639532 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,01760919 0,06628665 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,01760919 0,06617834 ! sensory cilium assembly GO:0035058 6 5 0,000 0,01760919 0,06607038 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,01760919 0,06596278 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01760919 0,06585552 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,01760919 0,06574861 ! spindle assembly GO:0051225 5 5 0,000 0,01760919 0,06564205 ! receptor biosynthetic process GO:0032800 6 5 0,000 0,01760919 0,06553583 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,01760919 0,06542996 ! organ regeneration GO:0031100 7 5 0,000 0,01760919 0,06532443 ! NAD biosynthetic process GO:0009435 7 5 0,000 0,01760919 0,06521924 ! carnitine metabolic process GO:0009437 5 5 0,000 0,01760919 0,06511438 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,01760919 0,06500986 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,01760919 0,06490568 GO:0055081|anion homeostasis, ! viral reproductive process GO:0022415 87 58 1,000 0,01800939 0,06627457 ! steroid hormone receptor signaling pathway GO:0030518 96 58 1,000 0,01800939 0,0661687 ! regulation of cellular response to stress GO:0080135 85 61 1,000 0,01980318 0,07264324 ! cell-matrix adhesion GO:0007160 114 61 1,000 0,01980318 0,07252756 ! urogenital system development GO:0001655 101 61 1,000 0,01980318 0,07241225 ! neurotransmitter transport GO:0006836 81 62 1,000 0,02041715 0,07453878 ! regulation of transcription factor activity GO:0051090 97 63 1,000 0,02103903 0,07668743 GO:0090046|regulation of transcription regulator activity, ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 1,000 0,02103903 0,07656608 ! viral reproduction GO:0016032 92 63 1,000 0,02103903 0,07644513 ! regulation of lipase activity GO:0060191 109 63 1,000 0,02103903 0,07632455 ! tRNA transcription GO:0009304 11 6 0,000 0,02109424 0,07640435 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,02109424 0,07628422 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,02109424 0,07616446 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,02109424 0,07604508 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,02109424 0,07592607 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,02109424 0,07580744 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,02109424 0,07568918 ! cytokinesis during cell cycle GO:0033205 9 6 0,000 0,02109424 0,07557128 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,02109424 0,07545375 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,02109424 0,07533659 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,02109424 0,07521979 ! prostate gland development GO:0030850 9 6 0,000 0,02109424 0,07510335 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,02109424 0,07498727 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,02109424 0,07487155 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,02109424 0,07475618 GO:0021872|generation of neurons in the forebrain, ! male meiosis GO:0007140 7 6 0,000 0,02109424 0,07464117 ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,02109424 0,07452652 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,02109424 0,07441221 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,02109424 0,07429826 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,02109424 0,07418465 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,02109424 0,07407139 ! regulation of protein export from nucleus GO:0046825 6 6 0,000 0,02109424 0,07395848 ! neuron adhesion GO:0007158 9 6 0,000 0,02109424 0,07384591 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,02109424 0,07373368 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,02109424 0,07362179 ! signal peptide processing GO:0006465 8 6 0,000 0,02109424 0,07351024 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,02109424 0,07339903 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,02109424 0,07328816 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,02109424 0,07317762 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,02109424 0,07306741 ! opsonization GO:0008228 8 6 0,000 0,02109424 0,07295754 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,02109424 0,07284799 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,02109424 0,07273877 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,02109424 0,07262988 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,02109424 0,07252132 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,02109424 0,07241308 ! photoreceptor cell development GO:0042461 10 6 0,000 0,02109424 0,07230516 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,02109424 0,07219756 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,02109424 0,07209028 ! mechanosensory behavior GO:0007638 8 6 0,000 0,02109424 0,07198333 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,02109424 0,07187668 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,02109424 0,07177036 ! response to interferon-gamma GO:0034341 12 6 0,000 0,02109424 0,07166435 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,02109424 0,07155865 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,02109424 0,07145326 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,02109424 0,07134818 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,02109424 0,07124341 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,02109424 0,07113895 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,02109424 0,07103479 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,02109424 0,07093094 ! thymic T cell selection GO:0045061 12 6 0,000 0,02109424 0,07082739 ! protein lipoylation GO:0009249 10 6 0,000 0,02109424 0,07072414 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,02109424 0,0706212 ! pigment granule organization GO:0048753 11 6 0,000 0,02109424 0,07051855 ! drug transport GO:0015893 6 6 0,000 0,02109424 0,0704162 ! cysteine metabolic process GO:0006534 7 6 0,000 0,02109424 0,07031415 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,02109424 0,07021239 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,02109424 0,07011093 ! histidine metabolic process GO:0006547 6 6 0,000 0,02109424 0,07000976 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,02109424 0,06990888 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,02109424 0,06980829 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,02109424 0,06970799 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,02109424 0,06960798 ! adenohypophysis development GO:0021984 10 6 0,000 0,02109424 0,06950825 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,02109424 0,06940881 ! hyperosmotic response GO:0006972 8 6 0,000 0,02109424 0,06930966 ! microtubule nucleation GO:0007020 10 6 0,000 0,02109424 0,06921079 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,02109424 0,0691122 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,02109424 0,06901389 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,02109424 0,06891585 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,02109424 0,0688181 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,02109424 0,06872063 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,02109424 0,06862343 ! response to dietary excess GO:0002021 7 6 0,000 0,02109424 0,0685265 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,02109424 0,06842985 ! cerebral cortex neuron differentiation GO:0021895 12 6 0,000 0,02109424 0,06833347 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,02109424 0,06823736 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,02109424 0,06814152 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,02109424 0,06804595 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,02109424 0,06795065 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,02109424 0,06785561 ! neuron apoptosis GO:0051402 8 6 0,000 0,02109424 0,06776084 ! organic alcohol transport GO:0015850 9 6 0,000 0,02109424 0,06766633 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,02109424 0,06757209 ! T cell mediated immunity GO:0002456 12 6 0,000 0,02109424 0,06747811 ! carnitine transport GO:0015879 8 6 0,000 0,02109424 0,06738439 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,02109424 0,06729093 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,02109424 0,06719773 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,02109424 0,06710479 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,02109424 0,0670121 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,02109424 0,06691967 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,02109424 0,0668275 ! parturition GO:0007567 12 6 0,000 0,02109424 0,06673557 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,02109424 0,0666439 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,02109424 0,06655249 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,02109424 0,06646132 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 0,000 0,02109424 0,0663704 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! spindle checkpoint GO:0031577 14 6 0,000 0,02109424 0,06627973 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,02109424 0,06618931 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,02109424 0,06609913 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,02109424 0,0660092 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,02109424 0,06591951 ! macrophage differentiation GO:0030225 10 6 0,000 0,02109424 0,06583007 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,02109424 0,06574087 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,02109424 0,06565191 ! interaction with symbiont GO:0051702 8 6 0,000 0,02109424 0,06556319 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,02109424 0,06547471 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,02109424 0,06538647 ! eating behavior GO:0042755 6 6 0,000 0,02109424 0,06529847 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,02109424 0,0652107 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,02109424 0,06512317 ! response to copper ion GO:0046688 9 6 0,000 0,02109424 0,06503587 ! DNA topological change GO:0006265 8 6 0,000 0,02109424 0,06494881 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,02109424 0,06486198 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,02109424 0,06477538 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,02109424 0,06468902 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,02109424 0,06460288 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,02109424 0,06451697 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,02109424 0,06443129 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,02109424 0,06434584 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,02109424 0,06426061 ! gas homeostasis GO:0033483 11 6 0,000 0,02109424 0,06417561 ! hair follicle maturation GO:0048820 7 6 0,000 0,02109424 0,06409083 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,02109424 0,06400628 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,02109424 0,06392195 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,02109424 0,06383784 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,02109424 0,06375396 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,02109424 0,06367029 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,02109424 0,06358684 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,02109424 0,06350361 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,02109424 0,0634206 ! histone ubiquitination GO:0016574 7 6 0,000 0,02109424 0,06333781 ! regulation of meiosis GO:0040020 10 6 0,000 0,02109424 0,06325523 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,02109424 0,06317287 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,02109424 0,06309072 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,02109424 0,06300878 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,02109424 0,06292706 ! membrane to membrane docking GO:0022614 12 6 0,000 0,02109424 0,06284555 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,02109424 0,06276425 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,02109424 0,06268315 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,02109424 0,06260227 ! receptor internalization GO:0031623 9 6 0,000 0,02109424 0,0625216 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,02109424 0,06244113 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,02109424 0,06236088 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,02109424 0,06228082 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,02109424 0,06220098 ! protein deubiquitination GO:0016579 8 6 0,000 0,02109424 0,06212133 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,02109424 0,06204189 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,02109424 0,06196266 ! axonal fasciculation GO:0007413 9 6 0,000 0,02109424 0,06188362 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,02109424 0,06180479 ! thiamin metabolic process GO:0006772 6 6 0,000 0,02109424 0,06172616 ! midbrain development GO:0030901 6 6 0,000 0,02109424 0,06164773 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,02109424 0,06156949 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,02109424 0,06149146 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 8 6 0,000 0,02109424 0,06141362 ! progesterone metabolic process GO:0042448 8 6 0,000 0,02109424 0,06133598 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,02109424 0,06125854 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,02109424 0,06118129 GO:0046479|glycosphingolipid catabolic process, ! negative regulation of axon extension GO:0030517 13 6 0,000 0,02109424 0,06110423 ! positive regulation of glucose import GO:0046326 6 6 0,000 0,02109424 0,06102737 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,02109424 0,06095071 ! adult feeding behavior GO:0008343 6 6 0,000 0,02109424 0,06087423 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,02109424 0,06079795 ! blastocyst growth GO:0001832 15 6 0,000 0,02109424 0,06072185 ! pigment granule transport GO:0051904 12 6 0,000 0,02109424 0,06064595 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,02109424 0,06057024 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,02109424 0,06049472 ! catecholamine transport GO:0051937 7 6 0,000 0,02109424 0,06041938 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,02109424 0,06034423 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,02109424 0,06026927 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,02109424 0,06019449 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,02109424 0,0601199 ! protein prenylation GO:0018342 10 6 0,000 0,02109424 0,0600455 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,02109424 0,05997128 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,02109424 0,05989724 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,02109424 0,05982338 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,02109424 0,05974971 ! cell cycle checkpoint GO:0000075 108 64 1,000 0,02166877 0,06130155 ! adaptive immune response GO:0002250 94 64 1,000 0,02166877 0,06122624 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! B cell activation GO:0042113 104 65 1,000 0,02230629 0,06295028 ! regulation of MAPKKK cascade GO:0043408 101 65 1,000 0,02230629 0,06287314 ! cell-substrate adhesion GO:0031589 121 66 1,000 0,02295155 0,0646127 ! axon guidance GO:0007411 99 66 1,000 0,02295155 0,06453371 ! regulation of neuron differentiation GO:0045664 107 67 1,000 0,02360448 0,06628854 ! learning or memory GO:0007611 123 68 1,000 0,02426502 0,06806043 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,02456713 0,06882387 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,02456713 0,06874015 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,02456713 0,06865662 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,02456713 0,0685733 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,02456713 0,06849018 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,02456713 0,06840726 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,02456713 0,06832455 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,02456713 0,06824203 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,02456713 0,06815971 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,02456713 0,06807759 ! reproductive behavior GO:0019098 12 7 0,000 0,02456713 0,06799567 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,02456713 0,06791394 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,02456713 0,06783241 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,02456713 0,06775108 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,02456713 0,06766994 ! oligopeptide transport GO:0006857 11 7 0,000 0,02456713 0,06758899 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,02456713 0,06750824 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,02456713 0,06742768 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,02456713 0,06734732 ! RNA methylation GO:0001510 11 7 0,000 0,02456713 0,06726714 ! pericardium development GO:0060039 8 7 0,000 0,02456713 0,06718716 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,02456713 0,06710736 ! fibril organization GO:0043206 13 7 0,000 0,02456713 0,06702776 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,02456713 0,06694834 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,02456713 0,06686911 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,02456713 0,06679007 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,02456713 0,06671122 ! lipoprotein transport GO:0042953 9 7 0,000 0,02456713 0,06663255 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,02456713 0,06655406 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,02456713 0,06647576 ! estrogen metabolic process GO:0008210 14 7 0,000 0,02456713 0,06639765 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,02456713 0,06631972 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,02456713 0,06624197 ! chemosensory behavior GO:0007635 9 7 0,000 0,02456713 0,0661644 ! microtubule bundle formation GO:0001578 8 7 0,000 0,02456713 0,06608702 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,02456713 0,06600981 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,02456713 0,06593279 ! leukocyte degranulation GO:0043299 10 7 0,000 0,02456713 0,06585594 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,02456713 0,06577928 ! reflex GO:0060004 12 7 0,000 0,02456713 0,06570279 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,02456713 0,06562648 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,02456713 0,06555035 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,02456713 0,06547439 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,02456713 0,06539861 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,02456713 0,06532301 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,02456713 0,06524757 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,02456713 0,06517232 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 0,000 0,02456713 0,06509723 ! adrenal gland development GO:0030325 17 7 0,000 0,02456713 0,06502232 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,02456713 0,06494759 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,02456713 0,06487302 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,02456713 0,06479862 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,02456713 0,0647244 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,02456713 0,06465034 ! endosome organization GO:0007032 10 7 0,000 0,02456713 0,06457646 ! thyroid hormone generation GO:0006590 11 7 0,000 0,02456713 0,06450274 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,02456713 0,06442919 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,02456713 0,06435581 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,02456713 0,06428259 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,02456713 0,06420955 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,02456713 0,06413666 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,02456713 0,06406395 ! galactose metabolic process GO:0006012 10 7 0,000 0,02456713 0,06399139 ! vesicle fusion GO:0006906 15 7 0,000 0,02456713 0,063919 ! intracellular pH reduction GO:0051452 10 7 0,000 0,02456713 0,06384678 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,02456713 0,06377472 ! organ growth GO:0035265 11 7 0,000 0,02456713 0,06370282 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,02456713 0,06363108 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,02456713 0,0635595 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,02456713 0,06348809 ! retinol metabolic process GO:0042572 9 7 0,000 0,02456713 0,06341683 ! behavioral fear response GO:0001662 13 7 0,000 0,02456713 0,06334574 GO:0002209|behavioral defense response, ! positive regulation of mitotic cell cycle GO:0045931 11 7 0,000 0,02456713 0,0632748 ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,02456713 0,06320403 ! rRNA modification GO:0000154 12 7 0,000 0,02456713 0,06313341 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,02456713 0,06306295 ! response to UV-B GO:0010224 11 7 0,000 0,02456713 0,06299264 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,02456713 0,06292249 ! intermediate filament organization GO:0045109 11 7 0,000 0,02456713 0,0628525 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,02456713 0,06278267 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,02456713 0,06271299 ! fibrinolysis GO:0042730 9 7 0,000 0,02456713 0,06264346 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,02456713 0,06257409 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,02456713 0,06250487 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,02456713 0,0624358 ! response to tropane GO:0014073 13 7 0,000 0,02456713 0,06236689 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,02456713 0,06229813 ! melanosome localization GO:0032400 10 7 0,000 0,02456713 0,06222951 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,02456713 0,06216106 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,02456713 0,06209275 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,02456713 0,06202459 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,02456713 0,06195658 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,02456713 0,06188872 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,02456713 0,06182101 ! mast cell activation GO:0045576 9 7 0,000 0,02456713 0,06175344 ! multicellular organismal aging GO:0010259 11 7 0,000 0,02456713 0,06168603 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,02456713 0,06161876 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,02456713 0,06155163 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,02456713 0,06148466 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,02456713 0,06141783 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,02456713 0,06135114 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,02456713 0,0612846 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,02456713 0,0612182 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,02456713 0,06115195 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,02456713 0,06108584 ! regulation of lipid transport GO:0032368 13 7 0,000 0,02456713 0,06101987 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,02456713 0,06095404 ! neuroblast proliferation GO:0007405 13 7 0,000 0,02456713 0,06088836 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,02456713 0,06082282 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,02456713 0,06075742 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,02456713 0,06069216 ! diuresis GO:0030146 12 7 0,000 0,02456713 0,06062704 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,02456713 0,06056206 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,02456713 0,06049722 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,02456713 0,06043251 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,02456713 0,06036795 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,02456713 0,06030352 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,02456713 0,06023923 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,02456713 0,06017508 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,02456713 0,06011106 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,02456713 0,06004718 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,02456713 0,05998344 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,02456713 0,05991983 ! lymph node development GO:0048535 9 7 0,000 0,02456713 0,05985636 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 0,000 0,02456713 0,05979302 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,02456713 0,05972981 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,02456713 0,05966674 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,02456713 0,0596038 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,02456713 0,05954099 ! ATP catabolic process GO:0006200 10 7 0,000 0,02456713 0,05947832 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,02456713 0,05941577 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,02456713 0,05935336 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,02456713 0,05929108 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,02456713 0,05922893 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,02456713 0,05916691 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,02456713 0,05910502 ! muscle adaptation GO:0043500 12 7 0,000 0,02456713 0,05904326 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,02456713 0,05898163 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,02456713 0,05892012 ! retina homeostasis GO:0001895 9 7 0,000 0,02456713 0,05885875 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,02456713 0,0587975 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,02456713 0,05873638 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,02456713 0,05867539 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,02456713 0,05861452 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,02456713 0,05855378 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,02456713 0,05849317 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,02456713 0,05843268 ! response to drug GO:0042493 108 69 1,000 0,02493311 0,0592419 ! response to metal ion GO:0010038 103 70 1,000 0,02560869 0,0607843 ! eye development GO:0001654 111 70 1,000 0,02560869 0,06072163 ! regulation of catabolic process GO:0009894 106 70 1,000 0,02560869 0,0606591 ! phosphoinositide-mediated signaling GO:0048015 109 71 1,000 0,0262917 0,06221286 ! mitochondrion organization GO:0007005 104 73 1,000 0,02767976 0,06543006 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,02802789 0,06618496 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,02802789 0,06611708 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! axon extension GO:0048675 11 8 0,000 0,02802789 0,06604934 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,02802789 0,06598174 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,02802789 0,06591427 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,02802789 0,06584694 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,02802789 0,06577975 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,02802789 0,0657127 ! phosphate transport GO:0006817 10 8 0,000 0,02802789 0,06564578 ! N-glycan processing GO:0006491 12 8 0,000 0,02802789 0,065579 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,02802789 0,06551235 ! UTP metabolic process GO:0046051 8 8 0,000 0,02802789 0,06544584 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,02802789 0,06537947 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,02802789 0,06531323 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,02802789 0,06524712 ! succinate metabolic process GO:0006105 14 8 0,000 0,02802789 0,06518115 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02802789 0,06511531 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,02802789 0,0650496 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,02802789 0,06498403 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,02802789 0,06491859 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,02802789 0,06485327 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,02802789 0,0647881 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02802789 0,06472305 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,02802789 0,06465813 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,02802789 0,06459334 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,02802789 0,06452868 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,02802789 0,06446416 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,02802789 0,06439976 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,02802789 0,06433548 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,02802789 0,06427134 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,02802789 0,06420733 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 0,000 0,02802789 0,06414344 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,02802789 0,06407968 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,02802789 0,06401604 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,02802789 0,06395253 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,02802789 0,06388915 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,02802789 0,0638259 ! melanin metabolic process GO:0006582 12 8 0,000 0,02802789 0,06376276 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,02802789 0,06369976 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02802789 0,06363688 ! macrophage activation GO:0042116 12 8 0,000 0,02802789 0,06357412 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,02802789 0,06351148 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,02802789 0,06344897 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! multicellular organism growth GO:0035264 14 8 0,000 0,02802789 0,06338658 ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,02802789 0,06332432 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,02802789 0,06326217 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,02802789 0,06320015 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,02802789 0,06313825 ! ruffle organization GO:0031529 11 8 0,000 0,02802789 0,06307647 ! osteoblast development GO:0002076 13 8 0,000 0,02802789 0,06301481 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,02802789 0,06295328 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,02802789 0,06289186 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,02802789 0,06283056 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,02802789 0,06276938 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,02802789 0,06270832 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,02802789 0,06264738 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,02802789 0,06258656 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,02802789 0,06252585 ! regulation of gliogenesis GO:0014013 20 8 0,000 0,02802789 0,06246527 GO:0045685|regulation of glial cell differentiation, ! brain morphogenesis GO:0048854 20 8 0,000 0,02802789 0,0624048 ! oligodendrocyte development GO:0014003 8 8 0,000 0,02802789 0,06234444 ! segment specification GO:0007379 10 8 0,000 0,02802789 0,06228421 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,02802789 0,06222409 ! cellular extravasation GO:0045123 11 8 0,000 0,02802789 0,06216408 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,02802789 0,0621042 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,02802789 0,06204442 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,02802789 0,06198476 ! snRNA metabolic process GO:0016073 10 8 0,000 0,02802789 0,06192522 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,02802789 0,06186579 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,02802789 0,06180648 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,02802789 0,06174728 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,02802789 0,06168819 ! nucleosome disassembly GO:0006337 12 8 0,000 0,02802789 0,06162921 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,02802789 0,06157035 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,02802789 0,0615116 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,02802789 0,06145296 ! icosanoid secretion GO:0032309 12 8 0,000 0,02802789 0,06139443 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,02802789 0,06133602 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02802789 0,06127771 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,02802789 0,06121952 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,02802789 0,06116144 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,02802789 0,06110346 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,02802789 0,0610456 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,02802789 0,06098785 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,02802789 0,0609302 ! sterol catabolic process GO:0016127 9 8 0,000 0,02802789 0,06087267 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,02802789 0,06081524 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,02802789 0,06075792 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,02802789 0,06070071 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,02802789 0,06064361 ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02802789 0,06058661 ! prophase GO:0051324 11 8 0,000 0,02802789 0,06052972 ! S phase GO:0051320 8 8 0,000 0,02802789 0,06047294 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,02802789 0,06041627 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,02802789 0,0603597 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,02802789 0,06030323 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,02802789 0,06024687 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,02802789 0,06019062 ! hormone catabolic process GO:0042447 13 8 0,000 0,02802789 0,06013447 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,02802789 0,06007843 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,02802789 0,06002249 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,02802789 0,05996666 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,02802789 0,05991092 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,02802789 0,0598553 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,02802789 0,05979977 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,02802789 0,05974435 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02802789 0,05968903 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,02802789 0,05963382 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,02802789 0,0595787 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,02802789 0,05952369 ! lamellipodium assembly GO:0030032 9 8 0,000 0,02802789 0,05946878 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02802789 0,05941397 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,02802789 0,05935926 ! cellular response to hormone stimulus GO:0032870 109 74 1,000 0,0283847 0,06005962 ! positive regulation of lymphocyte activation GO:0051251 108 74 1,000 0,0283847 0,06000442 ! response to inorganic substance GO:0010035 115 75 1,000 0,02909683 0,06145336 ! one-carbon metabolic process GO:0006730 110 77 1,000 0,03054245 0,06444736 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,03147658 0,06635758 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,03147658 0,06629682 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,03147658 0,06623616 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,03147658 0,06617562 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,03147658 0,06611518 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,03147658 0,06605486 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,03147658 0,06599464 ! SMAD protein nuclear translocation GO:0007184 15 9 0,000 0,03147658 0,06593454 ! GTP metabolic process GO:0046039 9 9 0,000 0,03147658 0,06587454 ! elastic fiber assembly GO:0048251 13 9 0,000 0,03147658 0,06581466 ! social behavior GO:0035176 14 9 0,000 0,03147658 0,06575488 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,03147658 0,06569521 ! artery development GO:0060840 19 9 0,000 0,03147658 0,06563565 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,03147658 0,0655762 ! response to pain GO:0048265 16 9 0,000 0,03147658 0,06551685 ! protein complex disassembly GO:0043241 17 9 0,000 0,03147658 0,06545762 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,03147658 0,06539849 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,03147658 0,06533946 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,03147658 0,06528054 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,03147658 0,06522173 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,03147658 0,06516303 ! protein targeting to ER GO:0045047 19 9 0,000 0,03147658 0,06510443 ! T cell selection GO:0045058 18 9 0,000 0,03147658 0,06504593 ! endoderm development GO:0007492 12 9 0,000 0,03147658 0,06498754 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,03147658 0,06492926 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,03147658 0,06487108 ! arginine catabolic process GO:0006527 10 9 0,000 0,03147658 0,064813 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,03147658 0,06475503 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,03147658 0,06469716 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,03147658 0,0646394 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,03147658 0,06458173 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,03147658 0,06452417 ! indolalkylamine metabolic process GO:0006586 14 9 0,000 0,03147658 0,06446672 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,03147658 0,06440936 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,03147658 0,06435211 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,03147658 0,06429496 ! mannose metabolic process GO:0006013 9 9 0,000 0,03147658 0,06423791 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,03147658 0,06418096 ! receptor clustering GO:0043113 15 9 0,000 0,03147658 0,06412411 ! epithelial cell development GO:0002064 10 9 0,000 0,03147658 0,06406737 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,03147658 0,06401072 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,03147658 0,06395417 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,03147658 0,06389773 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,03147658 0,06384138 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,03147658 0,06378513 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,03147658 0,06372898 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,03147658 0,06367293 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,03147658 0,06361698 ! blastoderm segmentation GO:0007350 11 9 0,000 0,03147658 0,06356113 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,03147658 0,06350537 ! DNA ligation GO:0006266 14 9 0,000 0,03147658 0,06344971 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,03147658 0,06339415 ! response to amine stimulus GO:0014075 13 9 0,000 0,03147658 0,06333869 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,03147658 0,06328333 ! erythrocyte development GO:0048821 11 9 0,000 0,03147658 0,06322806 ! renal water homeostasis GO:0003091 14 9 0,000 0,03147658 0,06317288 ! postreplication repair GO:0006301 11 9 0,000 0,03147658 0,06311781 ! mRNA cleavage GO:0006379 13 9 0,000 0,03147658 0,06306283 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,03147658 0,06300794 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,03147658 0,06295315 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,03147658 0,06289846 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,03147658 0,06284386 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,03147658 0,06278935 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,03147658 0,06273494 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,03147658 0,06268063 ! acid secretion GO:0046717 14 9 0,000 0,03147658 0,0626264 ! musculoskeletal movement GO:0050881 11 9 0,000 0,03147658 0,06257228 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,03147658 0,06251824 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,03147658 0,0624643 ! purine base metabolic process GO:0006144 18 9 0,000 0,03147658 0,06241045 ! oocyte differentiation GO:0009994 12 9 0,000 0,03147658 0,0623567 GO:0048599|oocyte development, ! thymus development GO:0048538 15 9 0,000 0,03147658 0,06230303 ! pyridine nucleotide biosynthetic process GO:0019363 11 9 0,000 0,03147658 0,06224946 ! spleen development GO:0048536 15 9 0,000 0,03147658 0,06219598 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,03147658 0,0621426 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,03147658 0,0620893 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,03147658 0,0620361 ! blastocyst formation GO:0001825 12 9 0,000 0,03147658 0,06198298 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,03147658 0,06192996 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,03147658 0,06187703 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,03147658 0,06182419 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,03147658 0,06177144 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,03147658 0,06171878 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,03147658 0,0616662 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,03147658 0,06161372 ! prepulse inhibition GO:0060134 14 9 0,000 0,03147658 0,06156133 ! embryonic placenta development GO:0001892 12 9 0,000 0,03147658 0,06150903 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,03147658 0,06145681 ! insulin secretion GO:0030073 17 9 0,000 0,03147658 0,06140469 ! sequestering of metal ion GO:0051238 11 9 0,000 0,03147658 0,06135265 ! response to nicotine GO:0035094 16 9 0,000 0,03147658 0,0613007 ! establishment of cell polarity GO:0030010 12 9 0,000 0,03147658 0,06124884 ! nucleus localization GO:0051647 15 9 0,000 0,03147658 0,06119706 ! regulation of synapse organization GO:0050807 12 9 0,000 0,03147658 0,06114537 ! regulation of cell cycle process GO:0010564 122 81 1,000 0,03351746 0,06505499 ! positive regulation of cell activation GO:0050867 120 81 1,000 0,03351746 0,06500014 GO:0002696|positive regulation of leukocyte activation, ! ossification GO:0001503 134 82 1,000 0,03427834 0,06641971 GO:0060348|bone development, ! detection of stimulus GO:0051606 108 82 1,000 0,03427834 0,0663638 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,03491322 0,06753608 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,03491322 0,06747933 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,03491322 0,06742267 ! thyroid gland development GO:0030878 19 10 0,000 0,03491322 0,06736611 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,03491322 0,06730964 ! synapsis GO:0007129 13 10 0,000 0,03491322 0,06725327 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,03491322 0,06719699 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,03491322 0,0671408 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,03491322 0,06708471 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,03491322 0,06702872 ! sulfate transport GO:0008272 12 10 0,000 0,03491322 0,06697281 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,03491322 0,066917 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,03491322 0,06686128 ! androgen metabolic process GO:0008209 13 10 0,000 0,03491322 0,06680566 ! phospholipid efflux GO:0033700 16 10 0,000 0,03491322 0,06675013 ! hippocampus development GO:0021766 19 10 0,000 0,03491322 0,06669469 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,03491322 0,06663934 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,03491322 0,06658408 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,03491322 0,06652892 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,03491322 0,06647384 ! pathogenesis GO:0009405 13 10 0,000 0,03491322 0,06641886 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,03491322 0,06636397 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,03491322 0,06630917 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,03491322 0,06625446 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 0,000 0,03491322 0,06619984 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,03491322 0,06614531 ! melanocyte differentiation GO:0030318 15 10 0,000 0,03491322 0,06609087 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,03491322 0,06603651 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,03491322 0,06598225 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,03491322 0,06592808 ! B cell proliferation GO:0042100 14 10 0,000 0,03491322 0,065874 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,03491322 0,06582 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,03491322 0,06576609 ! lipid digestion GO:0044241 15 10 0,000 0,03491322 0,06571228 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,03491322 0,06565855 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,03491322 0,0656049 ! UV protection GO:0009650 14 10 0,000 0,03491322 0,06555135 ! entry into host cell GO:0030260 20 10 0,000 0,03491322 0,06549788 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,03491322 0,0654445 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,03491322 0,06539121 ! negative regulation of ossification GO:0030279 19 10 0,000 0,03491322 0,065338 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,03491322 0,06528488 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,03491322 0,06523185 ! negative regulation of axonogenesis GO:0050771 23 10 0,000 0,03491322 0,0651789 ! regulation of organ growth GO:0046620 11 10 0,000 0,03491322 0,06512604 ! response to dsRNA GO:0043331 18 10 0,000 0,03491322 0,06507326 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,03491322 0,06502057 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,03491322 0,06496796 ! embryonic axis specification GO:0000578 12 10 0,000 0,03491322 0,06491544 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,03491322 0,06486301 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,03491322 0,06481065 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,03491322 0,06475839 ! fucose catabolic process GO:0019317 16 10 0,000 0,03491322 0,06470621 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,03491322 0,06465411 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,03491322 0,06460209 ! protein sumoylation GO:0016925 12 10 0,000 0,03491322 0,06455016 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,03491322 0,06449831 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,03491322 0,06444655 ! zymogen activation GO:0031638 14 10 0,000 0,03491322 0,06439487 ! salivary gland development GO:0007431 22 10 0,000 0,03491322 0,06434327 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,03491322 0,06429175 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,03491322 0,06424032 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,03491322 0,06418897 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,03491322 0,0641377 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,03491322 0,06408651 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,03491322 0,06403541 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,03491322 0,06398438 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,03491322 0,06393344 ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,03491322 0,06388258 ! detection of bacterium GO:0016045 10 10 0,000 0,03491322 0,0638318 ! activation of innate immune response GO:0002218 10 10 0,000 0,03491322 0,0637811 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,03491322 0,06373048 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,03491322 0,06367994 ! developmental induction GO:0031128 13 10 0,000 0,03491322 0,06362948 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,03491322 0,0635791 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,03491322 0,0635288 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,03491322 0,06347858 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,03660118 0,06649504 ! Wnt receptor signaling pathway GO:0016055 130 87 1,000 0,03818269 0,06931349 ! rRNA transcription GO:0009303 17 11 0,000 0,03833786 0,06954029 ! respiratory burst GO:0045730 14 11 0,000 0,03833786 0,06948549 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,03833786 0,06943077 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,03833786 0,06937615 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,03833786 0,06932161 ! double-strand break repair via homologous recombination GO:0000724 16 11 0,000 0,03833786 0,06926715 GO:0000725|recombinational repair, ! filopodium assembly GO:0046847 19 11 0,000 0,03833786 0,06921278 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,03833786 0,0691585 ! RNA polyadenylation GO:0043631 19 11 0,000 0,03833786 0,0691043 ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,03833786 0,06905018 ! mating GO:0007618 14 11 0,000 0,03833786 0,06899615 ! dopamine receptor signaling pathway GO:0007212 22 11 0,000 0,03833786 0,06894221 ! T cell proliferation GO:0042098 20 11 0,000 0,03833786 0,06888835 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,03833786 0,06883457 ! bone resorption GO:0045453 16 11 0,000 0,03833786 0,06878088 ! regulated secretory pathway GO:0045055 14 11 0,000 0,03833786 0,06872727 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,03833786 0,06867374 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,03833786 0,0686203 ! regulation of mRNA processing GO:0050684 18 11 0,000 0,03833786 0,06856694 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,03833786 0,06851366 ! oligodendrocyte differentiation GO:0048709 14 11 0,000 0,03833786 0,06846047 ! syncytium formation GO:0006949 15 11 0,000 0,03833786 0,06840736 ! plasma membrane organization GO:0007009 18 11 0,000 0,03833786 0,06835433 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,03833786 0,06830138 ! focal adhesion formation GO:0048041 24 11 0,000 0,03833786 0,06824852 ! mitotic spindle organization GO:0007052 15 11 0,000 0,03833786 0,06819573 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,03833786 0,06814303 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,03833786 0,06809041 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,03833786 0,06803787 ! adult heart development GO:0007512 11 11 0,000 0,03833786 0,06798541 ! actin cytoskeleton reorganization GO:0031532 21 11 0,000 0,03833786 0,06793304 ! temperature homeostasis GO:0001659 16 11 0,000 0,03833786 0,06788074 ! L-glutamate transport GO:0015813 16 11 0,000 0,03833786 0,06782853 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,03833786 0,06777639 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,03833786 0,06772433 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,03833786 0,06767236 ! stem cell development GO:0048864 29 11 0,000 0,03833786 0,06762046 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,03833786 0,06756865 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,03833786 0,06751691 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,03833786 0,06746525 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,03833786 0,06741367 ! vasoconstriction GO:0042310 15 11 0,000 0,03833786 0,06736217 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,03833786 0,06731075 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,03833786 0,06725941 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,03833786 0,06720814 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,03833786 0,06715696 ! ribosome assembly GO:0042255 13 11 0,000 0,03833786 0,06710585 ! histone deacetylation GO:0016575 13 11 0,000 0,03833786 0,06705482 ! chromatin silencing GO:0006342 19 11 0,000 0,03833786 0,06700386 ! nucleosome positioning GO:0016584 13 11 0,000 0,03833786 0,06695299 ! T cell homeostasis GO:0043029 20 11 0,000 0,03833786 0,06690219 ! regulation of isotype switching GO:0045191 19 11 0,000 0,03833786 0,06685147 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,03833786 0,06680082 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,03833786 0,06675025 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,03833786 0,06669976 ! aromatic amino acid family catabolic process GO:0009074 13 11 0,000 0,03833786 0,06664934 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,03833786 0,066599 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,03833786 0,06654874 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,03833786 0,06649855 ! male genitalia development GO:0030539 13 11 0,000 0,03833786 0,06644844 ! cholesterol efflux GO:0033344 19 11 0,000 0,03833786 0,06639841 ! biogenic amine catabolic process GO:0042402 21 11 0,000 0,03833786 0,06634844 ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,03833786 0,06629856 ! germ cell migration GO:0008354 18 11 0,000 0,03833786 0,06624875 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,03833786 0,06619901 ! defense response to fungus GO:0050832 12 11 0,000 0,03833786 0,06614935 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,03833786 0,06609976 ! lysogeny GO:0030069 18 11 0,000 0,03833786 0,06605025 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,03833786 0,06600081 ! acrosome reaction GO:0007340 13 11 0,000 0,03833786 0,06595145 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,03833786 0,06590215 ! reproductive developmental process GO:0003006 127 89 1,000 0,03979005 0,06834736 ! regulation of T cell activation GO:0050863 128 89 1,000 0,03979005 0,06829635 ! lactation GO:0007595 20 12 0,000 0,04175055 0,07160795 ! reproductive cellular process GO:0048610 14 12 0,000 0,04175055 0,07155459 ! tRNA modification GO:0006400 14 12 0,000 0,04175055 0,07150131 ! negative regulation of cell projection organization GO:0031345 26 12 0,000 0,04175055 0,07144811 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,04175055 0,07139499 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,04175055 0,07134195 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,04175055 0,07128898 ! non-recombinational repair GO:0000726 19 12 0,000 0,04175055 0,0712361 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,04175055 0,07118329 ! peroxisomal transport GO:0043574 21 12 0,000 0,04175055 0,07113056 ! cartilage condensation GO:0001502 18 12 0,000 0,04175055 0,07107791 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,04175055 0,07102534 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,04175055 0,07097285 ! heart looping GO:0001947 15 12 0,000 0,04175055 0,07092043 ! palate development GO:0060021 15 12 0,000 0,04175055 0,07086809 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,04175055 0,07081583 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 0,000 0,04175055 0,07076364 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,04175055 0,07071153 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,04175055 0,0706595 ! arginine metabolic process GO:0006525 13 12 0,000 0,04175055 0,07060755 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,04175055 0,07055567 ! methionine metabolic process GO:0006555 13 12 0,000 0,04175055 0,07050386 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,04175055 0,07045214 ! Golgi organization GO:0007030 18 12 0,000 0,04175055 0,07040049 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,04175055 0,07034891 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,04175055 0,07029741 ! monoamine transport GO:0015844 13 12 0,000 0,04175055 0,07024599 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,04175055 0,07019464 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! neutral amino acid transport GO:0015804 19 12 0,000 0,04175055 0,07014336 ! L-amino acid transport GO:0015807 20 12 0,000 0,04175055 0,07009216 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,04175055 0,07004104 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,04175055 0,06998999 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,04175055 0,06993901 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,04175055 0,06988811 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,04175055 0,06983728 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,04175055 0,06978653 ! cerebellum development GO:0021549 13 12 0,000 0,04175055 0,06973585 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,04175055 0,06968524 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,04175055 0,06963471 ! histone methylation GO:0016571 15 12 0,000 0,04175055 0,06958425 ! autonomic nervous system development GO:0048483 23 12 0,000 0,04175055 0,06953386 ! gland morphogenesis GO:0022612 23 12 0,000 0,04175055 0,06948355 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,04175055 0,06943331 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,04175055 0,06938314 ! regulation of epidermis development GO:0045682 17 12 0,000 0,04175055 0,06933304 ! intestinal absorption GO:0050892 19 12 0,000 0,04175055 0,06928302 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,04175055 0,06923307 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,04175055 0,06918319 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,04175055 0,06913338 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,04175055 0,06908364 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,04175055 0,06903398 ! microspike assembly GO:0030035 23 12 0,000 0,04175055 0,06898438 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,04175055 0,06893486 ! response to cold GO:0009409 14 12 0,000 0,04175055 0,06888541 ! response to oxidative stress GO:0006979 141 94 1,000 0,04391871 0,07241077 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,04515132 0,07438971 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,04515132 0,07433646 ! cGMP metabolic process GO:0046068 16 13 0,000 0,04515132 0,07428329 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,04515132 0,07423019 ! water transport GO:0006833 17 13 0,000 0,04515132 0,07417717 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,04515132 0,07412422 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,04515132 0,07407135 ! lipid localization GO:0010876 24 13 0,000 0,04515132 0,07401856 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,04515132 0,07396584 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,04515132 0,07391319 ! organelle fusion GO:0048284 28 13 0,000 0,04515132 0,07386062 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,04515132 0,07380813 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,04515132 0,07375571 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,04515132 0,07370336 ! response to hexose stimulus GO:0009746 19 13 0,000 0,04515132 0,07365109 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,04515132 0,07359889 ! glutamate metabolic process GO:0006536 18 13 0,000 0,04515132 0,07354677 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,04515132 0,07349472 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,04515132 0,07344274 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,04515132 0,07339084 ! NAD metabolic process GO:0019674 21 13 0,000 0,04515132 0,07333901 ! exocrine system development GO:0035272 27 13 0,000 0,04515132 0,07328725 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,04515132 0,07323557 ! bone mineralization GO:0030282 15 13 0,000 0,04515132 0,07318396 ! intermediate filament cytoskeleton organization GO:0045104 23 13 0,000 0,04515132 0,07313242 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,04515132 0,07308095 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,04515132 0,07302956 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,04515132 0,07297824 ! genitalia development GO:0048806 15 13 0,000 0,04515132 0,07292699 ! cellular pigmentation GO:0033059 24 13 0,000 0,04515132 0,07287581 ! tissue regeneration GO:0042246 21 13 0,000 0,04515132 0,07282471 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,04515132 0,07277368 ! cofactor transport GO:0051181 19 13 0,000 0,04515132 0,07272271 ! NADP metabolic process GO:0006739 18 13 0,000 0,04515132 0,07267182 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,04515132 0,072621 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,04515132 0,07257026 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,04515132 0,07251958 ! gas transport GO:0015669 18 13 0,000 0,04515132 0,07246897 ! heme biosynthetic process GO:0006783 20 13 0,000 0,04515132 0,07241843 ! regulation of axon extension GO:0030516 23 13 0,000 0,04515132 0,07236797 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,04515132 0,07231757 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,04515132 0,07226725 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,04515132 0,07221699 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,04515132 0,07216681 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,04515132 0,07211669 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,04515132 0,07206664 ! in utero embryonic development GO:0001701 147 96 1,000 0,04561316 0,07275331 ! extracellular structure organization GO:0043062 156 99 1,000 0,0481996 0,07682542 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,04854022 0,07731475 ! superoxide anion generation GO:0042554 18 14 0,000 0,04854022 0,07726124 ! neuron maturation GO:0042551 21 14 0,000 0,04854022 0,07720781 ! regulation of S phase GO:0033261 18 14 0,000 0,04854022 0,07715445 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,04854022 0,07710117 ! myotube differentiation GO:0014902 21 14 0,000 0,04854022 0,07704796 ! phosphoinositide phosphorylation GO:0046854 21 14 0,000 0,04854022 0,07699482 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,04854022 0,07694176 ! inositol metabolic process GO:0006020 20 14 0,000 0,04854022 0,07688877 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,04854022 0,07683585 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,04854022 0,07678301 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,04854022 0,07673024 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,04854022 0,07667754 ! gene silencing by RNA GO:0031047 20 14 0,000 0,04854022 0,07662491 ! response to cAMP GO:0051591 19 14 0,000 0,04854022 0,07657236 ! startle response GO:0001964 21 14 0,000 0,04854022 0,07651987 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,04854022 0,07646746 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,04854022 0,07641512 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,04854022 0,07636286 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,04854022 0,07631066 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,04854022 0,07625854 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,04854022 0,07620648 ! glycine metabolic process GO:0006544 22 14 0,000 0,04854022 0,0761545 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,04854022 0,07610259 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,04854022 0,07605075 ! regulation of heart rate GO:0002027 23 14 0,000 0,04854022 0,07599898 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,04854022 0,07594728 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,04854022 0,07589565 ! embryo implantation GO:0007566 27 14 0,000 0,04854022 0,07584409 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,04854022 0,0757926 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! intermediate filament-based process GO:0045103 24 14 0,000 0,04854022 0,07574118 ! axon cargo transport GO:0008088 27 14 0,000 0,04854022 0,07568983 ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,04854022 0,07563855 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,04854022 0,07558734 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,04854022 0,07553619 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,04854022 0,07548512 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,04854022 0,07543412 ! mRNA splice site selection GO:0006376 26 14 0,000 0,04854022 0,07538318 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,04854022 0,07533232 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,04854022 0,07528152 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,04854022 0,07523079 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,04854022 0,07518013 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,04854022 0,07512954 ! muscle maintenance GO:0046716 19 14 0,000 0,04854022 0,07507902 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,04854022 0,07502856 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,04854022 0,07497817 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,04854022 0,07492785 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,04854022 0,0748776 ! cell killing GO:0001906 20 14 0,000 0,04854022 0,07482741 ! cilium assembly GO:0042384 20 14 0,000 0,04854022 0,07477729 ! peptide hormone secretion GO:0030072 23 14 0,000 0,04854022 0,07472724 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,04907348 0,07549765 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,05191728 0,07981934 ! positive regulation of cell size GO:0045793 20 15 0,000 0,05191728 0,07976602 ! metencephalon development GO:0022037 19 15 0,000 0,05191728 0,07971277 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,05191728 0,0796596 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,05191728 0,07960649 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,05191728 0,07955346 ! skin development GO:0043588 25 15 0,000 0,05191728 0,07950049 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,05191728 0,0794476 ! lipid phosphorylation GO:0046834 23 15 0,000 0,05191728 0,07939477 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,05191728 0,07934202 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,05191728 0,07928933 ! bile acid metabolic process GO:0008206 22 15 0,000 0,05191728 0,07923672 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,05191728 0,07918418 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,05191728 0,0791317 ! adult walking behavior GO:0007628 25 15 0,000 0,05191728 0,0790793 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,05191728 0,07902696 ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 0,000 0,05191728 0,07897469 ! myoblast differentiation GO:0045445 27 15 0,000 0,05191728 0,0789225 ! centrosome cycle GO:0007098 16 15 0,000 0,05191728 0,07887037 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,05191728 0,07881831 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,05191728 0,07876632 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,05191728 0,07871439 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,05191728 0,07866254 ! response to osmotic stress GO:0006970 22 15 0,000 0,05191728 0,07861075 ! vesicle coating GO:0006901 25 15 0,000 0,05191728 0,07855904 ! DNA integration GO:0015074 22 15 0,000 0,05191728 0,07850739 ! peptidyl-serine phosphorylation GO:0018105 23 15 0,000 0,05191728 0,07845581 ! peptide secretion GO:0002790 27 15 0,000 0,05191728 0,07840429 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,05191728 0,07835285 ! regulation of vasodilation GO:0042312 24 15 0,000 0,05191728 0,07830147 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,05191728 0,07825015 ! neuron recognition GO:0008038 22 15 0,000 0,05191728 0,07819891 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,05191728 0,07814773 ! cellular amino acid derivative catabolic process GO:0042219 27 15 0,000 0,05191728 0,07809662 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,05191728 0,07804558 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,05191728 0,0779946 ! biomineral formation GO:0031214 18 15 0,000 0,05191728 0,07794369 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,05191728 0,07789285 ! regulation of T-helper cell differentiation GO:0045622 23 15 0,000 0,05191728 0,07784207 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,05191728 0,07779136 ! dopamine metabolic process GO:0042417 30 15 0,000 0,05191728 0,07774071 ! organic cation transport GO:0015695 19 15 0,000 0,05191728 0,07769013 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,05191728 0,07763962 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,05191728 0,07758917 ! defense response to virus GO:0051607 27 15 0,000 0,05191728 0,07753879 ! peptide hormone processing GO:0016486 19 15 0,000 0,05191728 0,07748847 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,05191728 0,07743822 ! protein secretion GO:0009306 27 16 0,000 0,05528254 0,08240431 ! hormone secretion GO:0046879 25 16 0,000 0,05528254 0,08235094 ! bone remodeling GO:0046849 24 16 0,000 0,05528254 0,08229764 ! endothelial cell migration GO:0043542 22 16 0,000 0,05528254 0,08224441 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,05528254 0,08219124 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,05528254 0,08213815 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,05528254 0,08208512 ! patterning of blood vessels GO:0001569 24 16 0,000 0,05528254 0,08203216 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,05528254 0,08197927 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,05528254 0,08192645 ! protein polyubiquitination GO:0000209 26 16 0,000 0,05528254 0,0818737 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,05528254 0,08182101 ! cellular response to unfolded protein GO:0034620 19 16 0,000 0,05528254 0,08176839 GO:0030968|endoplasmic reticulum unfolded protein response, ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,05528254 0,08171584 ! fructose metabolic process GO:0006000 20 16 0,000 0,05528254 0,08166336 ! regulation of protein binding GO:0043393 27 16 0,000 0,05528254 0,08161094 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,05528254 0,0815586 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,05528254 0,08150632 ! protein export from nucleus GO:0006611 24 16 0,000 0,05528254 0,0814541 ! negative regulation of immune response GO:0050777 28 16 0,000 0,05528254 0,08140195 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,05528254 0,08134987 ! DNA replication initiation GO:0006270 25 16 0,000 0,05528254 0,08129786 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,05528254 0,08124591 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 0,000 0,05528254 0,08119403 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,05528254 0,08114222 ! oogenesis GO:0048477 23 16 0,000 0,05528254 0,08109047 ! neural crest cell migration GO:0001755 24 16 0,000 0,05528254 0,08103878 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,05528254 0,08098717 GO:0006626|protein targeting to mitochondrion, ! detection of biotic stimulus GO:0009595 19 16 0,000 0,05528254 0,08093562 ! steroid catabolic process GO:0006706 22 16 0,000 0,05528254 0,08088413 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,05528254 0,08083271 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,05528254 0,08078135 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,05528254 0,08073006 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,05528254 0,08067884 ! sperm-egg recognition GO:0035036 16 16 0,000 0,05528254 0,08062768 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,05528254 0,08057659 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,05528254 0,08052556 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,05528254 0,08047459 ! negative regulation of translation GO:0017148 22 16 0,000 0,05528254 0,08042369 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,05863606 0,08524838 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,05863606 0,08519453 ! negative regulation of defense response GO:0031348 19 17 0,000 0,05863606 0,08514074 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,05863606 0,08508703 ! phosphatidylinositol metabolic process GO:0046488 22 17 0,000 0,05863606 0,08503338 ! glycerol metabolic process GO:0006071 20 17 0,000 0,05863606 0,0849798 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,05863606 0,08492628 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,05863606 0,08487283 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,05863606 0,08481946 ! signal complex assembly GO:0007172 29 17 0,000 0,05863606 0,08476614 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,05863606 0,0847129 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,05863606 0,08465972 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,05863606 0,08460661 ! memory GO:0007613 25 17 0,000 0,05863606 0,08455356 ! keratinization GO:0031424 17 17 0,000 0,05863606 0,08450059 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,05863606 0,08444767 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,05863606 0,08439483 ! retinoid metabolic process GO:0001523 22 17 0,000 0,05863606 0,08434205 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,05863606 0,08428933 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,05863606 0,08423669 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,05863606 0,0841841 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,05863606 0,08413159 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,05863606 0,08407914 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,05863606 0,08402675 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,05863606 0,08397443 ! membrane budding GO:0006900 29 17 0,000 0,05863606 0,08392217 ! heme metabolic process GO:0042168 27 17 0,000 0,05863606 0,08386998 ! actin filament bundle formation GO:0051017 26 17 0,000 0,05863606 0,08381786 ! negative regulation of protein catabolic process GO:0042177 26 17 0,000 0,05863606 0,0837658 ! body fluid secretion GO:0007589 27 17 0,000 0,05863606 0,0837138 ! stem cell differentiation GO:0048863 36 17 0,000 0,05863606 0,08366187 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,05863606 0,08361 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,05863606 0,0835582 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,05863606 0,08350646 ! sensory perception of pain GO:0019233 23 17 0,000 0,05863606 0,08345479 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,05863606 0,08340318 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,05863606 0,08335163 ! synaptogenesis GO:0007416 24 17 0,000 0,05863606 0,08330015 ! peptidyl-serine modification GO:0018209 27 17 0,000 0,05863606 0,08324873 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,05863606 0,08319737 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,05863606 0,08314608 ! cell-cell junction organization GO:0045216 25 17 0,000 0,05863606 0,08309485 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,05863606 0,08304368 ! aromatic compound catabolic process GO:0019439 22 17 0,000 0,05863606 0,08299258 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,05863606 0,08294153 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,05863606 0,08289056 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 0,000 0,06197786 0,08756086 ! positive regulation of translation GO:0045727 28 18 0,000 0,06197786 0,08750711 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,06197786 0,08745342 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,06197786 0,0873998 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,06197786 0,08734625 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,06197786 0,08729276 ! cAMP metabolic process GO:0046058 33 18 0,000 0,06197786 0,08723934 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,06197786 0,08718598 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,06197786 0,08713269 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,06197786 0,08707946 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,06197786 0,0870263 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,06197786 0,0869732 ! pancreas development GO:0031016 26 18 0,000 0,06197786 0,08692017 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,06197786 0,0868672 ! glutamine metabolic process GO:0006541 23 18 0,000 0,06197786 0,0868143 ! response to retinoic acid GO:0032526 25 18 0,000 0,06197786 0,08676146 ! pigmentation during development GO:0048066 31 18 0,000 0,06197786 0,08670869 ! central nervous system neuron development GO:0021954 30 18 0,000 0,06197786 0,08665597 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,06197786 0,08660333 ! fucose metabolic process GO:0006004 26 18 0,000 0,06197786 0,08655075 ! response to fungus GO:0009620 19 18 0,000 0,06197786 0,08649823 ! peptide cross-linking GO:0018149 31 18 0,000 0,06197786 0,08644577 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 0,000 0,06197786 0,08639338 ! heart process GO:0003015 27 18 0,000 0,06197786 0,08634105 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,06197786 0,08628879 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,06197786 0,08623659 ! visual learning GO:0008542 35 18 0,000 0,06197786 0,08618445 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,06197786 0,08613237 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,06197786 0,08608036 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,06197786 0,08602841 ! vitamin transport GO:0051180 24 18 0,000 0,06197786 0,08597652 ! hormone transport GO:0009914 27 18 0,000 0,06197786 0,0859247 ! negative regulation of neuron differentiation GO:0045665 24 18 0,000 0,06197786 0,08587294 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,06197786 0,08582124 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,06197786 0,0857696 ! cell-cell recognition GO:0009988 20 18 0,000 0,06197786 0,08571803 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,06197786 0,08566651 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,06197786 0,08561506 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,06197786 0,08556367 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,06530799 0,090107 ! positive regulation of protein catabolic process GO:0045732 23 19 0,000 0,06530799 0,09005298 ! positive regulation of ossification GO:0045778 30 19 0,000 0,06530799 0,08999903 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,06530799 0,08994513 ! reciprocal meiotic recombination GO:0007131 31 19 0,000 0,06530799 0,08989131 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,06530799 0,08983754 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,06530799 0,08978385 ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,06530799 0,08973021 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,06530799 0,08967664 ! regeneration GO:0031099 32 19 0,000 0,06530799 0,08962314 ! calcium-independent cell-cell adhesion GO:0016338 21 19 0,000 0,06530799 0,08956969 ! response to alkaloid GO:0043279 32 19 0,000 0,06530799 0,08951631 ! sensory perception of taste GO:0050909 23 19 0,000 0,06530799 0,089463 ! smooth muscle contraction GO:0006939 36 19 0,000 0,06530799 0,08940975 ! peroxisome organization GO:0007031 29 19 0,000 0,06530799 0,08935656 ! digestive system process GO:0022600 30 19 0,000 0,06530799 0,08930343 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,06530799 0,08925037 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,06530799 0,08919737 ! response to vitamin A GO:0033189 26 19 0,000 0,06530799 0,08914444 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,06530799 0,08909156 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,06530799 0,08903875 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,06530799 0,088986 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,06530799 0,08893332 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,06530799 0,0888807 ! plasma membrane fusion GO:0045026 23 19 0,000 0,06530799 0,08882813 ! cytolysis GO:0019835 20 19 0,000 0,06530799 0,08877564 ! renal system process GO:0003014 35 19 0,000 0,06530799 0,0887232 ! vasodilation GO:0042311 33 19 0,000 0,06530799 0,08867082 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,06530799 0,08861851 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,06530799 0,08856626 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,06530799 0,08851407 ! regulation of interleukin-2 production GO:0032663 31 19 0,000 0,06530799 0,08846194 ! negative regulation of angiogenesis GO:0016525 36 19 0,000 0,06530799 0,08840987 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,06530799 0,08835787 ! sarcomere organization GO:0045214 23 19 0,000 0,06530799 0,08830592 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,06530799 0,08825404 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,06530799 0,08820222 ! aromatic amino acid family metabolic process GO:0009072 24 19 0,000 0,06530799 0,08815045 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,06530799 0,08809875 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,06530799 0,08804711 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,06530799 0,08799553 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 0,000 0,06530799 0,08794401 ! protein stabilization GO:0050821 26 19 0,000 0,06530799 0,08789255 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,06862649 0,09230463 ! iron ion transport GO:0006826 37 20 0,000 0,06862649 0,09225068 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,06862649 0,0921968 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,06862649 0,09214298 GO:0006044|N-acetylglucosamine metabolic process, ! microtubule-based transport GO:0010970 37 20 0,000 0,06862649 0,09208922 ! response to vitamin GO:0033273 29 20 0,000 0,06862649 0,09203552 ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,06862649 0,09198189 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,06862649 0,09192832 ! response to ethanol GO:0045471 37 20 0,000 0,06862649 0,09187481 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,06862649 0,09182136 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,06862649 0,09176798 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,06862649 0,09171465 ! chromosome condensation GO:0030261 31 20 0,000 0,06862649 0,09166139 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,06862649 0,09160819 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,06862649 0,09155506 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,06862649 0,09150198 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,06862649 0,09144897 ! DNA modification GO:0006304 28 20 0,000 0,06862649 0,09139601 ! collagen fibril organization GO:0030199 45 20 0,000 0,06862649 0,09134312 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,06862649 0,09129029 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,06862649 0,09123752 ! collagen catabolic process GO:0030574 25 20 0,000 0,06862649 0,09118482 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,06862649 0,09113217 ! water-soluble vitamin biosynthetic process GO:0042364 22 20 0,000 0,06862649 0,09107958 ! alditol metabolic process GO:0019400 24 20 0,000 0,06862649 0,09102706 ! actin filament-based movement GO:0030048 34 20 0,000 0,06862649 0,09097459 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,07193339 0,09530345 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,07193339 0,09524859 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,07193339 0,09519378 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,07193339 0,09513904 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,07193339 0,09508437 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,07193339 0,09502975 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,07193339 0,0949752 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,07193339 0,09492071 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,07193339 0,09486628 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,07193339 0,09481192 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,07193339 0,09475762 ! vesicle docking GO:0048278 27 21 0,000 0,07193339 0,09470338 ! phototransduction GO:0007602 25 21 0,000 0,07193339 0,0946492 ! dendrite development GO:0016358 35 21 0,000 0,07193339 0,09459508 ! visual behavior GO:0007632 39 21 0,000 0,07193339 0,09454103 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,07193339 0,09448703 ! ovarian follicle development GO:0001541 30 21 0,000 0,07193339 0,0944331 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,07193339 0,09437923 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,07193339 0,09432543 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,07193339 0,09427168 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,07193339 0,09421799 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,07193339 0,09416437 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 0,000 0,07193339 0,09411081 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 0,000 0,07193339 0,0940573 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,07193339 0,09400386 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,07193339 0,09395048 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,07193339 0,09389716 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,07193339 0,0938439 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,07193339 0,0937907 ! fatty acid transport GO:0015908 30 21 0,000 0,07193339 0,09373756 ! immunoglobulin production GO:0002377 33 21 0,000 0,07193339 0,09368448 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,07193339 0,09363146 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,07193339 0,0935785 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,07193339 0,09352561 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,07193339 0,09347277 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,07193339 0,09341999 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,07193339 0,09336727 ! response to cytokine stimulus GO:0034097 47 21 0,000 0,07193339 0,09331461 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,07193339 0,093262 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,07193339 0,09320946 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,07193339 0,09315698 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,07193339 0,09310456 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,07193339 0,09305219 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,07193339 0,09299989 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,07522874 0,09720568 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,07522874 0,0971511 ! viral genome replication GO:0019079 29 22 0,000 0,07522874 0,09709658 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,07522874 0,09704212 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,07522874 0,09698773 ! leukocyte adhesion GO:0007159 38 22 0,000 0,07522874 0,09693339 ! molting cycle process GO:0022404 40 22 0,000 0,07522874 0,09687912 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! dicarboxylic acid metabolic process GO:0043648 33 22 0,000 0,07522874 0,0968249 ! glutamate signaling pathway GO:0007215 34 22 0,000 0,07522874 0,09677075 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,07522874 0,09671666 ! microtubule organizing center organization GO:0031023 28 22 0,000 0,07522874 0,09666263 GO:0051297|centrosome organization, ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,07522874 0,09660866 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,07522874 0,09655475 ! lysosome organization GO:0007040 37 22 0,000 0,07522874 0,09650089 ! barbed-end actin filament capping GO:0051016 33 22 0,000 0,07522874 0,0964471 GO:0051693|actin filament capping, ! coenzyme catabolic process GO:0009109 33 22 0,000 0,07522874 0,09639337 ! vitamin biosynthetic process GO:0009110 24 22 0,000 0,07522874 0,0963397 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,07522874 0,09628609 ! membrane depolarization GO:0051899 35 22 0,000 0,07522874 0,09623254 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,07522874 0,09617905 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,07522874 0,09612561 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,07522874 0,09607224 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,07522874 0,09601893 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,07522874 0,09596567 ! blastocyst development GO:0001824 37 22 0,000 0,07522874 0,09591247 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,07851258 0,10004373 ! embryonic pattern specification GO:0009880 31 23 0,000 0,07851258 0,09998833 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,07851258 0,099933 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,07851258 0,09987773 ! vesicle targeting GO:0006903 32 23 0,000 0,07851258 0,09982252 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,07851258 0,09976737 ! osteoblast differentiation GO:0001649 40 23 0,000 0,07851258 0,09971228 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,07851258 0,09965725 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,07851258 0,09960228 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,07851258 0,09954737 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,07851258 0,09949252 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,07851258 0,09943774 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,07851258 0,09938301 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,07851258 0,09932835 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,07851258 0,09927374 ! cell fate determination GO:0001709 45 23 0,000 0,07851258 0,09921919 ! pentose metabolic process GO:0019321 31 23 0,000 0,07851258 0,09916471 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,07851258 0,09911028 ! spermatid development GO:0007286 33 23 0,000 0,07851258 0,09905591 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,07851258 0,09900161 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,07851258 0,09894736 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,07851258 0,09889317 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,07851258 0,09883904 ! telomere organization GO:0032200 32 23 0,000 0,07851258 0,09878497 GO:0000723|telomere maintenance, ! negative regulation of catabolic process GO:0009895 34 23 0,000 0,07851258 0,09873096 ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,07851258 0,09867701 ! regulation of amine transport GO:0051952 38 23 0,000 0,07851258 0,09862312 ! liver development GO:0001889 40 23 0,000 0,07851258 0,09856929 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,08178494 0,10262159 ! initiation of viral infection GO:0019059 42 24 0,000 0,08178494 0,10256563 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,08178494 0,10250974 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,08178494 0,10245391 ! superoxide metabolic process GO:0006801 32 24 0,000 0,08178494 0,10239813 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,08178494 0,10234242 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,08178494 0,10228677 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,08178494 0,10223118 ! sperm motility GO:0030317 27 24 0,000 0,08178494 0,10217565 ! vacuole organization GO:0007033 39 24 0,000 0,08178494 0,10212018 ! receptor metabolic process GO:0043112 37 24 0,000 0,08178494 0,10206477 ! neural crest cell development GO:0014032 39 24 0,000 0,08178494 0,10200942 GO:0014033|neural crest cell differentiation, ! regulation of alpha-beta T cell activation GO:0046634 35 24 0,000 0,08178494 0,10195413 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,08178494 0,1018989 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,08178494 0,10184373 ! glutathione metabolic process GO:0006749 29 24 0,000 0,08178494 0,10178862 ! negative regulation of actin filament depolymerization GO:0030835 36 25 0,000 0,08504588 0,10578989 ! negative regulation of actin filament polymerization GO:0030837 36 25 0,000 0,08504588 0,10573271 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,08504588 0,10567559 ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,08504588 0,10561853 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,08504588 0,10556153 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,08504588 0,10550459 ! peptide transport GO:0015833 43 25 0,000 0,08504588 0,10544772 ! male gonad development GO:0008584 33 25 0,000 0,08504588 0,1053909 ! iron ion homeostasis GO:0055072 39 25 0,000 0,08504588 0,10533415 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,08504588 0,10527746 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,08504588 0,10522082 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,08504588 0,10516425 ! phospholipid transport GO:0015914 35 25 0,000 0,08504588 0,10510774 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,08504588 0,1050513 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,08504588 0,10499491 ! detection of light stimulus GO:0009583 30 25 0,000 0,08504588 0,10493858 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,08504588 0,10488231 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,08504588 0,10482611 GO:0032943|mononuclear cell proliferation, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,08829541 0,10877314 ! translational initiation GO:0006413 43 26 0,000 0,08829541 0,10871491 ! circadian rhythm GO:0007623 42 26 0,000 0,08829541 0,10865674 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,08829541 0,10859863 ! post-embryonic development GO:0009791 42 26 0,000 0,08829541 0,10854059 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,08829541 0,10848261 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,08829541 0,10842469 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,08829541 0,10836683 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 0,000 0,08829541 0,10830904 ! nicotinamide metabolic process GO:0006769 39 26 0,000 0,08829541 0,1082513 GO:0046496|nicotinamide nucleotide metabolic process, ! spermatid differentiation GO:0048515 36 26 0,000 0,08829541 0,10819363 ! negative regulation of protein polymerization GO:0032272 38 26 0,000 0,08829541 0,10813602 ! regulation of coagulation GO:0050818 39 26 0,000 0,08829541 0,10807847 ! alkaloid metabolic process GO:0009820 40 27 0,000 0,09153359 0,11198259 ! regulation of actin filament depolymerization GO:0030834 39 27 0,000 0,09153359 0,11192305 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,09153359 0,11186358 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,09153359 0,11180418 ! membrane docking GO:0022406 39 27 0,000 0,09153359 0,11174483 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,09153359 0,11168555 ! catechol metabolic process GO:0009712 43 27 0,000 0,09153359 0,11162633 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,09153359 0,11156718 ! acute-phase response GO:0006953 42 27 0,000 0,09153359 0,11150808 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,09153359 0,11144905 ! myofibril assembly GO:0030239 36 27 0,000 0,09153359 0,11139009 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,09153359 0,11133118 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,09153359 0,11127234 ! natural killer cell activation GO:0030101 35 27 0,000 0,09153359 0,11121356 ! lipid oxidation GO:0034440 38 27 0,000 0,09153359 0,11115484 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,09153359 0,11109618 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,09153359 0,11103759 ! negative regulation of transcription regulator activity GO:0090048 47 27 0,000 0,09153359 0,11097905 GO:0043433|negative regulation of transcription factor activity, ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,09153359 0,11092058 ! gene silencing GO:0016458 41 27 0,000 0,09153359 0,11086217 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,09476046 0,11471003 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,09476046 0,11464968 ! phenol metabolic process GO:0018958 44 28 0,000 0,09476046 0,11458941 ! negative regulation of protein complex assembly GO:0031333 42 28 0,000 0,09476046 0,11452919 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,09476046 0,11446904 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,09476046 0,11440895 ! cell junction assembly GO:0034329 56 28 0,000 0,09476046 0,11434892 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,09476046 0,11428896 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,09476046 0,11422906 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,09476046 0,11416923 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,09476046 0,11410945 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,09476046 0,11404974 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,09476046 0,11399009 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,09476046 0,1139305 GO:0002764|immune response-regulating signal transduction, ! response to organic cyclic substance GO:0014070 47 28 0,000 0,09476046 0,11387098 ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,09476046 0,11381151 ! positive regulation of T cell differentiation GO:0045582 39 28 0,000 0,09476046 0,11375211 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,09476046 0,11369278 ! mesoderm formation GO:0001707 46 28 0,000 0,09476046 0,1136335 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,09476046 0,11357428 ! BMP signaling pathway GO:0030509 40 28 0,000 0,09476046 0,11351513 ! pyridine nucleotide metabolic process GO:0019362 41 28 0,000 0,09476046 0,11345604 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,09476046 0,11339701 ! placenta development GO:0001890 37 28 0,000 0,09476046 0,11333804 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,09797604 0,11712313 ! regulation of innate immune response GO:0045088 38 29 0,000 0,09797604 0,11706229 ! ovulation cycle process GO:0022602 41 29 0,000 0,09797604 0,11700151 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,09797604 0,11694079 ! protein targeting to membrane GO:0006612 53 29 0,000 0,09797604 0,11688014 ! mismatch repair GO:0006298 34 29 0,000 0,09797604 0,11681954 ! muscle cell development GO:0055001 38 29 0,000 0,09797604 0,11675902 ! formation of primary germ layer GO:0001704 48 29 0,000 0,09797604 0,11669855 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,09797604 0,11663815 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,09797604 0,11657781 ! tissue homeostasis GO:0001894 42 29 0,000 0,09797604 0,11651753 GO:0048871|multicellular organismal homeostasis, ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,10118039 0,1202661 ! collagen metabolic process GO:0032963 40 30 0,000 0,10118039 0,12020398 ! organic anion transport GO:0015711 51 30 0,000 0,10118039 0,12014192 ! cholesterol transport GO:0030301 46 30 0,000 0,10118039 0,12007993 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 49 30 0,000 0,10118039 0,120018 ! spindle organization GO:0007051 37 30 0,000 0,10118039 0,11995613 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,10118039 0,11989433 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,10118039 0,1198326 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,10118039 0,11977092 ! ceramide metabolic process GO:0006672 43 30 0,000 0,10118039 0,11970931 ! ovulation cycle GO:0042698 43 30 0,000 0,10118039 0,11964776 ! hindbrain development GO:0030902 45 30 0,000 0,10118039 0,11958628 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,10118039 0,11952486 ! adult locomotory behavior GO:0008344 47 30 0,000 0,10118039 0,1194635 ! regulation of microtubule-based process GO:0032886 58 30 0,000 0,10118039 0,11940221 ! response to heat GO:0009408 41 30 0,000 0,10118039 0,11934097 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,10118039 0,11927981 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,10118039 0,1192187 ! negative regulation of secretion GO:0051048 49 31 0,000 0,10437354 0,12291815 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,10437354 0,12285524 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,10437354 0,1227924 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,10437354 0,12272962 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,10437354 0,12266691 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,10437354 0,12260426 ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,10437354 0,12254167 ! RNA modification GO:0009451 40 31 0,000 0,10437354 0,12247915 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,10755553 0,12614876 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,10755553 0,12608446 ! meiosis I GO:0007127 52 32 0,000 0,10755553 0,12602023 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,10755553 0,12595606 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,10755553 0,12589196 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,10755553 0,12582793 GO:0006639|acylglycerol metabolic process, ! regulation of protein stability GO:0031647 48 32 0,000 0,10755553 0,12576396 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 0,000 0,10755553 0,12570006 ! cytokine production GO:0001816 44 32 0,000 0,10755553 0,12563622 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,10755553 0,12557244 ! vesicle localization GO:0051648 47 32 0,000 0,10755553 0,12550873 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 0,000 0,11072639 0,12914335 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! RNA export from nucleus GO:0006405 44 33 0,000 0,11072639 0,1290779 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,11072639 0,12901251 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,11072639 0,12894719 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,11072639 0,12888193 ! sister chromatid segregation GO:0000819 46 33 0,000 0,11072639 0,12881674 ! ear morphogenesis GO:0042471 42 33 0,000 0,11072639 0,12875161 ! actomyosin structure organization GO:0031032 43 33 0,000 0,11072639 0,12868656 ! cell junction organization GO:0034330 63 33 0,000 0,11072639 0,12862156 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,11072639 0,12855663 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,11072639 0,12849177 ! nucleus organization GO:0006997 49 33 0,000 0,11072639 0,12842698 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,11072639 0,12836224 ! female gonad development GO:0008585 49 33 0,000 0,11072639 0,12829758 ! positive regulation of cell development GO:0010720 54 33 0,000 0,11072639 0,12823298 ! lipid homeostasis GO:0055088 55 33 0,000 0,11072639 0,12816844 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,11072639 0,12810397 ! regulation of proteolysis GO:0030162 50 33 0,000 0,11072639 0,12803956 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,11072639 0,12797522 ! cytokinesis GO:0000910 52 33 0,000 0,11072639 0,12791095 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,11072639 0,12784673 ! mRNA catabolic process GO:0006402 48 34 0,000 0,11388617 0,13142909 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,11388617 0,13136318 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,11388617 0,13129733 ! feeding behavior GO:0007631 45 34 0,000 0,11388617 0,13123155 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,11388617 0,13116584 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,11388617 0,13110019 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,11388617 0,13103461 ! female gamete generation GO:0007292 43 34 0,000 0,11388617 0,13096909 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,11388617 0,13090364 ! polyol metabolic process GO:0019751 44 34 0,000 0,11388617 0,13083825 ! aerobic respiration GO:0009060 47 34 0,000 0,11388617 0,13077293 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,1170349 0,13432149 ! Notch signaling pathway GO:0007219 56 35 0,000 0,1170349 0,1342545 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,1170349 0,13418757 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,1170349 0,13412071 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,1170349 0,13405392 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,1170349 0,13398719 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,1170349 0,13392053 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 51 35 0,000 0,1170349 0,13385394 ! glycogen metabolic process GO:0005977 48 35 0,000 0,1170349 0,13378741 ! pigment metabolic process GO:0042440 61 35 0,000 0,1170349 0,13372095 ! response to reactive oxygen species GO:0000302 55 36 0,000 0,12017262 0,13723785 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,12017262 0,13716974 ! cellular amide metabolic process GO:0043603 52 36 0,000 0,12017262 0,1371017 ! organic ether metabolic process GO:0018904 46 36 0,000 0,12017262 0,13703373 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,12017262 0,13696582 ! development of primary female sexual characteristics GO:0046545 52 36 0,000 0,12017262 0,13689798 GO:0046660|female sex differentiation, ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,12017262 0,13683021 ! glucan metabolic process GO:0044042 49 36 0,000 0,12017262 0,13676251 GO:0006073|cellular glucan metabolic process, ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,12329937 0,14025151 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,12329937 0,14018218 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,12329937 0,14011292 ! learning GO:0007612 67 37 0,000 0,12329937 0,14004373 ! ion transmembrane transport GO:0034220 56 37 0,000 0,12329937 0,13997461 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,12329937 0,13990555 ! regulation of protein secretion GO:0050708 51 37 0,000 0,12329937 0,13983656 ! amino acid activation GO:0043038 52 37 0,000 0,12329937 0,13976765 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 0,000 0,12329937 0,13969879 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,12641519 0,14315851 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,12641519 0,14308806 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,12641519 0,14301767 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,12641519 0,14294736 ! phagocytosis GO:0006909 60 38 0,000 0,12641519 0,14287712 ! pigmentation GO:0043473 74 38 0,000 0,12641519 0,14280694 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,12952011 0,14624264 ! negative regulation of protein complex disassembly GO:0043242 67 39 0,000 0,12952011 0,14617088 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,12952011 0,14609919 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,12952011 0,14602757 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,12952011 0,14595603 ! male sex differentiation GO:0046661 53 39 0,000 0,12952011 0,14588455 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,12952011 0,14581314 ! chromatin remodeling GO:0006338 68 39 0,000 0,12952011 0,14574181 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,12952011 0,14567054 ! cell growth GO:0016049 61 39 0,000 0,12952011 0,14559934 ! regulation of actin filament polymerization GO:0030833 59 40 0,000 0,13261417 0,14900469 ! regulation of tube size GO:0035150 60 40 0,000 0,13261417 0,14893193 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,13261417 0,14885925 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 0,000 0,13261417 0,14878663 ! peptide metabolic process GO:0006518 56 40 0,000 0,13261417 0,14871409 ! inner ear development GO:0048839 57 40 0,000 0,13261417 0,14864162 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,13261417 0,14856922 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! epidermal cell differentiation GO:0009913 53 40 0,000 0,13261417 0,14849688 ! JAK-STAT cascade GO:0007259 53 40 0,000 0,13261417 0,14842462 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,13569742 0,15180158 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,13569742 0,15172779 ! energy reserve metabolic process GO:0006112 59 41 0,000 0,13569742 0,15165406 ! glucose transport GO:0015758 52 41 0,000 0,13569742 0,15158041 ! endosome transport GO:0016197 71 41 0,000 0,13569742 0,15150682 ! striated muscle contraction GO:0006941 62 41 0,000 0,13569742 0,15143331 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,13569742 0,15135987 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,13876988 0,15471193 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,13876988 0,15463697 ! cellular component disassembly GO:0022411 64 42 0,000 0,13876988 0,15456209 ! hexose transport GO:0008645 54 42 0,000 0,13876988 0,15448728 GO:0015749|monosaccharide transport, ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 0,000 0,13876988 0,15441254 ! excretion GO:0007588 63 42 0,000 0,13876988 0,15433787 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,13876988 0,15426327 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,13876988 0,15418875 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,13876988 0,1541143 ! neuromuscular process GO:0050905 79 43 0,000 0,14183159 0,15743854 ! DNA-dependent DNA replication GO:0006261 59 43 0,000 0,14183159 0,15736259 ! tRNA processing GO:0008033 49 43 0,000 0,14183159 0,15728672 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 0,000 0,14183159 0,15721092 ! vesicle organization GO:0016050 79 43 0,000 0,14183159 0,15713519 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,14488259 0,16043811 ! glycolysis GO:0006096 53 44 0,000 0,14488259 0,1603609 ! regulation of ion transport GO:0043269 57 44 0,000 0,14488259 0,16028377 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,14488259 0,16020671 ! negative regulation of cell migration GO:0030336 92 44 0,000 0,14488259 0,16012973 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,14488259 0,16005281 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,14488259 0,15997598 ! RNA catabolic process GO:0006401 64 45 0,000 0,14792292 0,16325466 ! regulation of translational initiation GO:0006446 64 45 0,000 0,14792292 0,16317636 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,14792292 0,16309814 ! cell recognition GO:0008037 58 45 0,000 0,14792292 0,16301999 ! cell maturation GO:0048469 60 45 0,000 0,14792292 0,16294192 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,15095262 0,16619962 ! regulation of protein complex disassembly GO:0043244 77 46 0,000 0,15095262 0,1661201 ! cell redox homeostasis GO:0045454 63 46 0,000 0,15095262 0,16604066 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,15095262 0,16596129 ! regulation of adaptive immune response GO:0002819 72 46 0,000 0,15095262 0,165882 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,15397171 0,16911888 ! viral infectious cycle GO:0019058 71 47 0,000 0,15397171 0,16903815 ! response to estrogen stimulus GO:0043627 74 47 0,000 0,15397171 0,16895751 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,15397171 0,16887694 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,15397171 0,16879644 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,15397171 0,16871602 ! regulation of protein polymerization GO:0032271 71 47 0,000 0,15397171 0,16863568 ! chloride transport GO:0006821 67 48 0,000 0,15698024 0,17184891 ! response to temperature stimulus GO:0009266 62 48 0,000 0,15698024 0,17176715 ! cellular polysaccharide metabolic process GO:0044264 63 48 0,000 0,15698024 0,17168548 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 0,000 0,15698024 0,17160388 ! gastrulation GO:0007369 73 48 0,000 0,15698024 0,17152236 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,15698024 0,17144091 GO:0019724|B cell mediated immunity, ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 0,000 0,15698024 0,17135954 ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,15698024 0,17127825 ! regulation of endocytosis GO:0030100 63 48 0,000 0,15698024 0,17119704 ! nuclear export GO:0051168 69 48 0,000 0,15698024 0,1711159 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,15698024 0,17103485 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,15997825 0,17421874 ! sensory perception of smell GO:0007608 61 49 0,000 0,15997825 0,17413628 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,15997825 0,17405391 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,15997825 0,17397162 ! RNA elongation GO:0006354 62 49 0,000 0,15997825 0,1738894 ! germ cell development GO:0007281 68 49 0,000 0,15997825 0,17380726 ! heterocycle catabolic process GO:0046700 72 49 0,000 0,15997825 0,1737252 ! regulation of actin filament length GO:0030832 72 50 0,000 0,16296576 0,17688592 ! ear development GO:0043583 72 50 0,000 0,16296576 0,17680248 ! membrane fusion GO:0006944 80 50 0,000 0,16296576 0,17671912 ! negative regulation of cytoskeleton organization GO:0051494 84 50 0,000 0,16296576 0,17663584 ! lipid modification GO:0030258 73 50 0,000 0,16296576 0,17655264 ! proton transport GO:0015992 75 50 0,000 0,16296576 0,17646952 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,16296576 0,17638647 ! positive regulation of secretion GO:0051047 71 51 0,000 0,16594282 0,17952422 ! hydrogen transport GO:0006818 77 51 0,000 0,16594282 0,17943982 ! regulation of protein catabolic process GO:0042176 77 51 0,000 0,16594282 0,1793555 ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,16594282 0,17927125 ! adult behavior GO:0030534 80 51 0,000 0,16594282 0,17918709 ! negative regulation of cell motion GO:0051271 104 51 0,000 0,16594282 0,179103 ! transition metal ion transport GO:0000041 74 52 0,000 0,16890947 0,18221941 ! regulation of cellular component size GO:0032535 74 52 0,000 0,16890947 0,18213398 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,16890947 0,18204863 ! establishment of organelle localization GO:0051656 85 52 0,000 0,16890947 0,18196336 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,17186573 0,18506141 ! single fertilization GO:0007338 59 53 0,000 0,17186573 0,18497481 ! amino acid transport GO:0006865 84 54 0,000 0,17481164 0,18805742 ! regulation of protein complex assembly GO:0043254 81 54 0,000 0,17481164 0,1879695 ! glucose catabolic process GO:0006007 66 54 0,000 0,17481164 0,18788167 ! cytokine-mediated signaling pathway GO:0019221 76 54 0,000 0,17481164 0,18779391 ! DNA catabolic process GO:0006308 67 54 0,000 0,17481164 0,18770624 ! detection of external stimulus GO:0009581 66 54 0,000 0,17481164 0,18761865 ! cellular amino acid catabolic process GO:0009063 74 54 0,000 0,17481164 0,18753114 ! exocytosis GO:0006887 74 55 0,000 0,17774724 0,19059145 ! mesoderm development GO:0007498 76 55 0,000 0,17774724 0,19050264 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,17774724 0,19041391 ! water-soluble vitamin metabolic process GO:0006767 71 55 0,000 0,17774724 0,19032526 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,18067257 0,19336757 ! carbohydrate transport GO:0008643 74 57 0,000 0,18358766 0,1963961 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,18358766 0,19630479 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,18358766 0,19621357 ! coenzyme biosynthetic process GO:0009108 67 57 0,000 0,18358766 0,19612244 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,18358766 0,19603139 ! secondary metabolic process GO:0019748 84 57 0,000 0,18358766 0,19594042 ! developmental maturation GO:0021700 75 57 0,000 0,18358766 0,19584954 ! gonad development GO:0008406 79 57 0,000 0,18358766 0,19575874 ! regulation of cytokine biosynthetic process GO:0042035 76 58 0,000 0,18649254 0,19876406 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,18649254 0,19867199 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,18938725 0,20166235 ! actin filament organization GO:0007015 95 59 0,000 0,18938725 0,20156903 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,18938725 0,2014758 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,18938725 0,20138265 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 0,000 0,19227183 0,20435545 ! phosphoinositide metabolic process GO:0030384 87 60 0,000 0,19227183 0,20426106 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 0,000 0,19227183 0,20416676 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,19227183 0,20407254 ! fertilization GO:0009566 68 60 0,000 0,19227183 0,20397841 ! meiosis GO:0007126 96 61 0,000 0,1951463 0,20693246 GO:0051327|M phase of meiotic cell cycle, ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,1951463 0,2068371 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,1951463 0,20674182 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,1951463 0,20664664 ! extracellular matrix organization GO:0030198 103 61 0,000 0,1951463 0,20655154 ! negative regulation of ligase activity GO:0051352 91 61 0,000 0,1951463 0,20645653 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 0,000 0,1951463 0,20636161 ! amine catabolic process GO:0009310 90 62 0,000 0,19801072 0,20929442 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,19801072 0,20919828 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,19801072 0,20910223 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 0,000 0,19801072 0,20900626 ! meiotic cell cycle GO:0051321 97 62 0,000 0,19801072 0,20891039 ! organelle localization GO:0051640 96 62 0,000 0,19801072 0,2088146 ! cAMP-mediated signaling GO:0019933 97 63 0,000 0,2008651 0,21172765 ! regulation of actin cytoskeleton organization GO:0032956 97 64 0,000 0,20370948 0,21462749 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,20370948 0,21452922 ! hexose catabolic process GO:0019320 82 64 0,000 0,20370948 0,21443104 ! reproductive structure development GO:0048608 90 65 0,000 0,20654391 0,21731518 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 0,000 0,20654391 0,21721582 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 0,000 0,20654391 0,21711654 ! defense response to bacterium GO:0042742 73 65 0,000 0,20654391 0,21701736 ! positive regulation of T cell activation GO:0050870 94 65 0,000 0,20654391 0,21691826 ! activation of immune response GO:0002253 83 65 0,000 0,20654391 0,21681926 ! regulation of actin filament-based process GO:0032970 99 66 0,000 0,20936841 0,219684 ! antigen processing and presentation GO:0019882 96 66 0,000 0,20936841 0,21958383 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,20936841 0,21948375 ! regulation of immune effector process GO:0002697 101 66 0,000 0,20936841 0,21938375 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,21218301 0,22223175 ! acute inflammatory response GO:0002526 92 68 0,000 0,21498776 0,22506684 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,21498776 0,22496444 ! development of primary sexual characteristics GO:0045137 92 68 0,000 0,21498776 0,22486214 ! intracellular protein transmembrane transport GO:0065002 102 68 0,000 0,21498776 0,22475993 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,21498776 0,22465781 ! rhythmic process GO:0048511 105 68 0,000 0,21498776 0,22455579 ! inorganic anion transport GO:0015698 93 68 0,000 0,21498776 0,22445386 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,21778268 0,22726868 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,21778268 0,22716561 ! positive regulation of ligase activity GO:0051351 99 69 0,000 0,21778268 0,22706263 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 0,000 0,22056781 0,22986224 ! humoral immune response GO:0006959 86 70 0,000 0,22056781 0,22975814 ! amine transport GO:0015837 101 70 0,000 0,22056781 0,22965413 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,22056781 0,22955021 ! muscle cell differentiation GO:0042692 104 71 0,000 0,22334318 0,23233348 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,22334318 0,23222845 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 0,000 0,22334318 0,23212351 ! steroid biosynthetic process GO:0006694 94 71 0,000 0,22334318 0,23201866 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,22334318 0,23191391 ! negative regulation of organelle organization GO:0010639 115 72 0,000 0,22610883 0,23467974 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,22610883 0,23457389 ! regulation of blood pressure GO:0008217 107 73 0,000 0,22886479 0,23732598 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,22886479 0,23721903 ! response to steroid hormone stimulus GO:0048545 114 73 0,000 0,22886479 0,23711217 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,23161109 0,2398494 ! digestion GO:0007586 97 74 0,000 0,23161109 0,23974146 ! blood coagulation GO:0007596 116 75 0,000 0,23434777 0,24246508 GO:0050817|coagulation, ! response to nutrient GO:0007584 104 75 0,000 0,23434777 0,24235606 ! regulation of ligase activity GO:0051340 114 75 0,000 0,23434777 0,24224714 ! cofactor biosynthetic process GO:0051188 92 75 0,000 0,23434777 0,24213831 ! amine biosynthetic process GO:0009309 97 76 0,000 0,23707486 0,24484606 ! tRNA metabolic process GO:0006399 95 76 0,000 0,23707486 0,24473617 ! response to unfolded protein GO:0006986 99 76 0,000 0,23707486 0,24462637 ! regulation of adenylate cyclase activity GO:0045761 131 77 0,000 0,23979239 0,24731951 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,23979239 0,24720865 ! sex differentiation GO:0007548 105 77 0,000 0,23979239 0,2470979 ! protein ubiquitination GO:0016567 125 77 0,000 0,23979239 0,24698724 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,23979239 0,24687668 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,23979239 0,24676622 ! nitrogen compound catabolic process GO:0044270 114 78 0,000 0,2425004 0,24944138 ! regulation of cyclase activity GO:0031279 132 78 0,000 0,2425004 0,24932987 ! regulation of cAMP biosynthetic process GO:0030817 136 79 0,000 0,24519892 0,25199174 ! cellular respiration GO:0045333 107 79 0,000 0,24519892 0,25187919 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,24519892 0,25176675 ! regulation of lyase activity GO:0051339 133 79 0,000 0,24519892 0,2516544 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,24519892 0,25154216 ! chromatin assembly GO:0031497 102 80 0,000 0,24788798 0,2541874 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,24788798 0,25407413 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 0,000 0,24788798 0,25396096 GO:0010498|proteasomal protein catabolic process, ! regulation of GTPase activity GO:0043087 129 80 0,000 0,24788798 0,25384788 ! regulation of cAMP metabolic process GO:0030814 141 81 0,000 0,25056761 0,25647775 ! hemostasis GO:0007599 125 81 0,000 0,25056761 0,25636366 ! mRNA transport GO:0051028 121 81 0,000 0,25056761 0,25624966 ! response to protein stimulus GO:0051789 111 81 0,000 0,25056761 0,25613578 ! regulation of neurological system process GO:0031644 122 81 0,000 0,25056761 0,25602199 ! vitamin metabolic process GO:0006766 103 81 0,000 0,25056761 0,2559083 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 0,000 0,25589872 0,26123704 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 0,000 0,25589872 0,26112114 ! microtubule cytoskeleton organization GO:0000226 120 84 0,000 0,25855027 0,26370981 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,25855027 0,26359292 ! sterol metabolic process GO:0016125 120 84 0,000 0,25855027 0,26347613 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,26119252 0,26605084 ! rRNA metabolic process GO:0016072 107 85 0,000 0,26119252 0,26593307 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,26119252 0,2658154 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 0,000 0,26382551 0,26837623 ! nucleosome organization GO:0034728 114 87 0,000 0,26644926 0,27092542 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,26644926 0,2708057 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,26644926 0,27068609 ! female pregnancy GO:0007565 130 87 0,000 0,26644926 0,27056658 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,26906381 0,27310096 ! anatomical structure homeostasis GO:0060249 136 88 0,000 0,26906381 0,27298049 ! carboxylic acid catabolic process GO:0046395 122 88 0,000 0,26906381 0,27286013 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 0,000 0,26906381 0,27273987 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! protein processing GO:0016485 114 88 0,000 0,26906381 0,27261972 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,2716692 0,27513833 ! regulation of nucleotide metabolic process GO:0006140 150 89 0,000 0,2716692 0,27501723 ! protein modification by small protein conjugation GO:0032446 140 90 0,000 0,27426544 0,27752333 ! hormone metabolic process GO:0042445 121 90 0,000 0,27426544 0,27740128 ! RNA localization GO:0006403 135 91 0,000 0,27685258 0,27989492 ! ATP metabolic process GO:0046034 137 91 0,000 0,27685258 0,27977194 ! response to virus GO:0009615 122 91 0,000 0,27685258 0,27964907 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 0,000 0,27943065 0,28212928 ! glycerophospholipid metabolic process GO:0006650 130 92 0,000 0,27943065 0,28200548 ! positive regulation of immune response GO:0050778 121 92 0,000 0,27943065 0,28188179 ! DNA recombination GO:0006310 146 92 0,000 0,27943065 0,28175822 ! sulfur metabolic process GO:0006790 118 92 0,000 0,27943065 0,28163475 ! regulation of cytoskeleton organization GO:0051493 154 93 0,000 0,28199967 0,28409954 ! polysaccharide metabolic process GO:0005976 129 93 0,000 0,28199967 0,28397515 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,28199967 0,28385087 ! electron transport chain GO:0022900 123 94 0,000 0,28455968 0,28630239 ! carboxylic acid transport GO:0046942 147 95 0,000 0,28711071 0,28874274 GO:0015849|organic acid transport, ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 0,000 0,28965279 0,29117195 ! regulation of cellular component biogenesis GO:0044087 158 96 0,000 0,28965279 0,29104474 ! protein modification by small protein conjugation or removal GO:0070647 148 96 0,000 0,28965279 0,29091765 ! protein maturation GO:0051604 129 96 0,000 0,28965279 0,29079067 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,29218595 0,2932058 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 0,000 0,29218595 0,29307793 ! calcium ion transport GO:0006816 167 99 0,000 0,29722564 0,29800304 ! regulation of translation GO:0006417 151 100 0,000 0,29973223 0,30038524 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,29973223 0,30025441 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 0,000 0,29973223 0,30012369 ! divalent metal ion transport GO:0070838 171 100 0,000 0,29973223 0,29999309 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,29973223 0,2998626 ! Ras protein signal transduction GO:0007265 162 100 0,000 0,29973223 0,29973223