pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6413-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of intracellular protein transport GO:0033157 25 25 4,000 2,844E-07 5,242E-04 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 3,000 3,476E-07 3,203E-04 GO:0032388|positive regulation of intracellular transport, ! regulation of nucleocytoplasmic transport GO:0046822 27 27 4,000 4,284E-07 2,632E-04 ! protein amino acid autophosphorylation GO:0046777 28 28 4,000 5,192E-07 2,392E-04 ! regulation of intracellular transport GO:0032386 31 31 4,000 8,86E-07 3,266E-04 ! actin cytoskeleton reorganization GO:0031532 5 5 2,000 1,949E-06 5,985E-04 ! nucleus localization GO:0051647 5 5 2,000 1,949E-06 5,13E-04 ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 2,000 3,881E-06 8,941E-04 ! phosphoinositide-mediated signaling GO:0048015 45 45 4,000 5,992E-06 1,227E-03 ! regulation of protein transport GO:0051223 53 53 4,000 1,359E-05 2,505E-03 GO:0070201|regulation of establishment of protein localization, ! positive regulation of protein import into nucleus GO:0042307 9 9 2,000 1,61E-05 2,697E-03 ! regulation of protein localization GO:0032880 58 57 4,000 1,949E-05 2,993E-03 ! peptidyl-amino acid modification GO:0018193 61 59 4,000 2,31E-05 3,274E-03 ! positive regulation of protein transport GO:0051222 29 29 3,000 2,315E-05 3,048E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 2,000 3,136E-05 3,853E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 2,000 5,391E-05 6,21E-03 ! positive regulation of cell migration GO:0030335 36 36 3,000 5,571E-05 6,04E-03 ! meiosis GO:0007126 37 37 3,000 6,22E-05 6,369E-03 GO:0051327|M phase of meiotic cell cycle, ! lung development GO:0030324 38 37 3,000 6,22E-05 6,033E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 6,833E-05 6,297E-03 ! meiotic cell cycle GO:0051321 38 38 3,000 6,922E-05 6,075E-03 ! respiratory tube development GO:0030323 40 39 3,000 7,68E-05 6,434E-03 ! respiratory system development GO:0060541 40 39 3,000 7,68E-05 6,154E-03 ! positive regulation of cell motion GO:0051272 39 39 3,000 7,68E-05 5,897E-03 ! regulation of transcription factor import into nucleus GO:0042990 15 15 2,000 8,506E-05 6,271E-03 ! positive regulation of catabolic process GO:0009896 16 16 2,000 1,043E-04 7,39E-03 ! tissue remodeling GO:0048771 17 17 2,000 1,261E-04 8,606E-03 ! regulation of cellular localization GO:0060341 86 85 4,000 1,351E-04 8,891E-03 ! Wnt receptor signaling pathway GO:0016055 46 45 3,000 1,356E-04 8,616E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 2,000 1,507E-04 9,256E-03 ! positive regulation of transferase activity GO:0051347 91 88 4,000 1,592E-04 9,466E-03 GO:0033674|positive regulation of kinase activity, ! regulation of catabolic process GO:0009894 48 47 3,000 1,609E-04 9,267E-03 ! positive regulation of MAP kinase activity GO:0043406 50 49 3,000 1,895E-04 0,01058315 ! regulation of protein import into nucleus GO:0042306 21 21 2,000 2,425E-04 0,01314654 ! negative regulation of protein transport GO:0051224 21 21 2,000 2,425E-04 0,01277093 ! response to hypoxia GO:0001666 53 53 3,000 2,574E-04 0,01317895 ! response to oxygen levels GO:0070482 55 54 3,000 2,768E-04 0,01378916 ! reproductive developmental process GO:0003006 56 56 3,000 3,188E-04 0,0154596 ! positive regulation of glucose metabolic process GO:0010907 5 5 1,000 3,426E-04 0,01619042 ! prostate gland development GO:0030850 5 5 1,000 3,426E-04 0,01578566 ! filopodium assembly GO:0046847 7 5 1,000 3,426E-04 0,01540065 GO:0030035|microspike assembly, ! mRNA stabilization GO:0048255 5 5 1,000 3,426E-04 0,01503396 GO:0043489|RNA stabilization, ! dopamine receptor signaling pathway GO:0007212 5 5 1,000 3,426E-04 0,01468434 ! hippocampus development GO:0021766 6 5 1,000 3,426E-04 0,0143506 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 3,426E-04 0,0140317 ! receptor clustering GO:0043113 5 5 1,000 3,426E-04 0,01372666 ! protein heterooligomerization GO:0051291 5 5 1,000 3,426E-04 0,01343461 ! negative regulation of focal adhesion formation GO:0051895 6 5 1,000 3,426E-04 0,01315472 ! zymogen activation GO:0031638 5 5 1,000 3,426E-04 0,01288625 ! peptidyl-lysine modification GO:0018205 5 5 1,000 3,426E-04 0,01262853 ! peptidyl-histidine modification GO:0018202 5 5 1,000 3,426E-04 0,01238091 ! positive regulation of viral reproduction GO:0048524 5 5 1,000 3,426E-04 0,01214282 ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 1,000 3,426E-04 0,01191371 ! androgen receptor signaling pathway GO:0030521 24 24 2,000 3,645E-04 0,01244119 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 5,12E-04 0,0171557 GO:0018409|peptide or protein amino-terminal blocking, ! virus-host interaction GO:0019048 6 6 1,000 5,12E-04 0,01684934 ! regulation of lipid kinase activity GO:0043550 6 6 1,000 5,12E-04 0,01655374 ! regulation of positive chemotaxis GO:0050926 6 6 1,000 5,12E-04 0,01626833 GO:0050927|positive regulation of positive chemotaxis, ! limbic system development GO:0021761 7 6 1,000 5,12E-04 0,0159926 ! ER overload response GO:0006983 6 6 1,000 5,12E-04 0,01572606 ! negative regulation of T cell proliferation GO:0042130 6 6 1,000 5,12E-04 0,01546825 GO:0070667|negative regulation of mast cell proliferation, ! regulation of vascular permeability GO:0043114 6 6 1,000 5,12E-04 0,01521876 ! peptidyl-serine phosphorylation GO:0018105 6 6 1,000 5,12E-04 0,0149772 ! regulation of bone resorption GO:0045124 6 6 1,000 5,12E-04 0,01474318 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 5,12E-04 0,01451636 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 1,000 5,12E-04 0,01429641 ! regulation of focal adhesion formation GO:0051893 7 6 1,000 5,12E-04 0,01408303 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 1,000 5,12E-04 0,01387593 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! regulation of embryonic development GO:0045995 6 6 1,000 5,12E-04 0,01367483 ! localization within membrane GO:0051668 6 6 1,000 5,12E-04 0,01347948 ! regulation of MAP kinase activity GO:0043405 67 66 3,000 5,992E-04 0,01555304 ! regulation of epithelial cell proliferation GO:0050678 29 29 2,000 6,446E-04 0,01650053 ! establishment of organelle localization GO:0051656 31 30 2,000 7,133E-04 0,01800815 ! positive regulation of cellular catabolic process GO:0031331 7 7 1,000 7,141E-04 0,01778382 ! double-strand break repair via homologous recombination GO:0000724 7 7 1,000 7,141E-04 0,0175467 GO:0000725|recombinational repair, ! regulation of mRNA processing GO:0050684 7 7 1,000 7,141E-04 0,01731582 ! negative regulation of lymphocyte proliferation GO:0050672 7 7 1,000 7,141E-04 0,01709094 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 1,000 7,141E-04 0,01687183 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! negative regulation of cell-substrate adhesion GO:0010812 8 7 1,000 7,141E-04 0,01665826 GO:0001953|negative regulation of cell-matrix adhesion, ! regulation of mRNA stability GO:0043488 7 7 1,000 7,141E-04 0,01645003 ! negative regulation of T cell activation GO:0050868 7 7 1,000 7,141E-04 0,01624694 ! positive regulation of transport GO:0051050 71 70 3,000 7,493E-04 0,01684032 ! regulation of DNA replication GO:0006275 32 31 2,000 7,865E-04 0,01746313 ! regulation of cell migration GO:0030334 71 71 3,000 7,906E-04 0,01734616 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 9,485E-04 0,02056528 ! positive regulation of endothelial cell migration GO:0010595 8 8 1,000 9,485E-04 0,02032615 ! sex determination GO:0007530 8 8 1,000 9,485E-04 0,02009252 ! peptidyl-serine modification GO:0018209 8 8 1,000 9,485E-04 0,01986419 ! positive regulation of leukocyte migration GO:0002687 8 8 1,000 9,485E-04 0,019641 ! regulation of RNA stability GO:0043487 8 8 1,000 9,485E-04 0,01942277 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 1,000 9,485E-04 0,01920933 ! cytoplasmic sequestering of protein GO:0051220 8 8 1,000 9,485E-04 0,01900053 ! regulation of protein catabolic process GO:0042176 35 34 2,000 1,034E-03 0,02049249 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 1,126E-03 0,02208379 ! regulation of locomotion GO:0040012 79 79 3,000 1,181E-03 0,02291679 ! regulation of cell motion GO:0051270 79 79 3,000 1,181E-03 0,02267807 ! positive regulation of cell projection organization GO:0031346 9 9 1,000 1,215E-03 0,02308262 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 1,215E-03 0,02284709 ! positive regulation of endothelial cell proliferation GO:0001938 9 9 1,000 1,215E-03 0,02261631 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 1,000 1,215E-03 0,02239014 ! cerebral cortex development GO:0021987 9 9 1,000 1,215E-03 0,02216846 ! regulation of dephosphorylation GO:0035303 9 9 1,000 1,215E-03 0,02195112 ! histone acetylation GO:0016573 9 9 1,000 1,215E-03 0,021738 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 1,215E-03 0,02152899 ! regulation of leukocyte migration GO:0002685 9 9 1,000 1,215E-03 0,02132395 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 1,215E-03 0,02112278 ! tube development GO:0035295 83 81 3,000 1,297E-03 0,0223376 ! regulation of transcription factor activity GO:0051090 38 37 2,000 1,326E-03 0,02263089 GO:0090046|regulation of transcription regulator activity, ! steroid hormone receptor signaling pathway GO:0030518 38 38 2,000 1,434E-03 0,02424495 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 1,000 1,513E-03 0,02534741 ! regulation of glucose metabolic process GO:0010906 10 10 1,000 1,513E-03 0,02511906 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 1,513E-03 0,02489478 ! phototransduction GO:0007602 11 10 1,000 1,513E-03 0,02467447 ! calcium-independent cell-cell adhesion GO:0016338 10 10 1,000 1,513E-03 0,02445803 ! neuromuscular junction development GO:0007528 10 10 1,000 1,513E-03 0,02424535 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 1,513E-03 0,02403634 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 1,513E-03 0,0238309 ! protein stabilization GO:0050821 10 10 1,000 1,513E-03 0,02362894 ! protein oligomerization GO:0051259 39 39 2,000 1,547E-03 0,02395907 ! positive regulation of protein kinase activity GO:0045860 89 86 3,000 1,62E-03 0,02488287 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 2,000 1,666E-03 0,02536864 ! organelle localization GO:0051640 41 40 2,000 1,666E-03 0,0251607 ! heart development GO:0007507 90 87 3,000 1,691E-03 0,02533698 ! myeloid leukocyte differentiation GO:0002573 12 11 1,000 1,842E-03 0,02737883 ! signal complex assembly GO:0007172 11 11 1,000 1,842E-03 0,0271598 ! protein amino acid acetylation GO:0006473 11 11 1,000 1,842E-03 0,02694424 ! detection of light stimulus involved in sensory perception GO:0050962 12 11 1,000 1,842E-03 0,02673208 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! regulation of viral genome replication GO:0045069 11 11 1,000 1,842E-03 0,02652324 ! apoptotic nuclear changes GO:0030262 11 11 1,000 1,842E-03 0,02631763 ! interaction with host GO:0051701 11 11 1,000 1,842E-03 0,02611519 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 1,842E-03 0,02591584 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 1,000 1,842E-03 0,0257195 GO:0006109|regulation of carbohydrate metabolic process, ! negative regulation of lymphocyte activation GO:0051250 11 11 1,000 1,842E-03 0,02552612 ! reproductive structure development GO:0048608 43 43 2,000 2,055E-03 0,0282615 ! positive regulation of protein catabolic process GO:0045732 12 12 1,000 2,202E-03 0,03006385 ! pallium development GO:0021543 13 12 1,000 2,202E-03 0,0298428 ! somitogenesis GO:0001756 13 12 1,000 2,202E-03 0,02962497 ! detection of light stimulus GO:0009583 13 12 1,000 2,202E-03 0,02941029 ! regulation of DNA binding GO:0051101 47 45 2,000 2,343E-03 0,03106954 ! positive regulation of DNA replication GO:0045740 14 13 1,000 2,593E-03 0,03413204 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 1,000 2,593E-03 0,03388997 ! negative regulation of protein modification process GO:0031400 13 13 1,000 2,593E-03 0,03365131 ! vasculogenesis GO:0001570 13 13 1,000 2,593E-03 0,03341599 ! receptor metabolic process GO:0043112 14 13 1,000 2,593E-03 0,03318393 ! negative regulation of protein catabolic process GO:0042177 13 13 1,000 2,593E-03 0,03295508 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 2,593E-03 0,03272936 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 2,593E-03 0,03250671 ! regulation of viral reproduction GO:0050792 13 13 1,000 2,593E-03 0,03228707 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 1,000 2,593E-03 0,03207038 ! positive regulation of locomotion GO:0040017 13 13 1,000 2,593E-03 0,03185657 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! negative regulation of intracellular transport GO:0032387 13 13 1,000 2,593E-03 0,0316456 ! negative regulation of leukocyte activation GO:0002695 13 13 1,000 2,593E-03 0,03143741 ! regulation of cell-substrate adhesion GO:0010810 14 13 1,000 2,593E-03 0,03123194 GO:0001952|regulation of cell-matrix adhesion, ! tissue homeostasis GO:0001894 13 13 1,000 2,593E-03 0,03102913 GO:0048871|multicellular organismal homeostasis, ! protein tetramerization GO:0051262 13 13 1,000 2,593E-03 0,03082894 ! posttranscriptional regulation of gene expression GO:0010608 98 98 3,000 2,618E-03 0,03092646 ! sex differentiation GO:0007548 47 47 2,000 2,656E-03 0,03117478 ! anti-apoptosis GO:0006916 100 99 3,000 2,716E-03 0,03168461 ! ossification GO:0001503 50 49 2,000 2,993E-03 0,03468911 GO:0060348|bone development, ! gland development GO:0048732 51 49 2,000 2,993E-03 0,0344723 ! skeletal muscle tissue development GO:0007519 50 49 2,000 2,993E-03 0,03425819 GO:0060538|skeletal muscle organ development, ! protein amino acid acylation GO:0043543 14 14 1,000 3,014E-03 0,03428341 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 1,000 3,014E-03 0,03407308 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of behavior GO:0050795 14 14 1,000 3,014E-03 0,03386532 ! base-excision repair GO:0006284 14 14 1,000 3,014E-03 0,03366007 ! regulation of DNA metabolic process GO:0051052 51 50 2,000 3,171E-03 0,0352018 ! negative regulation of transport GO:0051051 51 50 2,000 3,171E-03 0,03499101 ! negative regulation of protein complex assembly GO:0031333 15 15 1,000 3,464E-03 0,03800144 ! detection of stimulus involved in sensory perception GO:0050906 16 15 1,000 3,464E-03 0,03777658 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 3,464E-03 0,03755437 ! ovarian follicle development GO:0001541 15 15 1,000 3,464E-03 0,03733475 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 3,464E-03 0,03711769 ! chromosome condensation GO:0030261 15 15 1,000 3,464E-03 0,03690313 ! response to mechanical stimulus GO:0009612 15 15 1,000 3,464E-03 0,03669105 ! negative regulation of transcription factor activity GO:0043433 16 15 1,000 3,464E-03 0,03648138 GO:0090048|negative regulation of transcription regulator activity, ! negative regulation of cell activation GO:0050866 15 15 1,000 3,464E-03 0,0362741 ! protein homooligomerization GO:0051260 15 15 1,000 3,464E-03 0,03606917 ! response to light stimulus GO:0009416 53 52 2,000 3,546E-03 0,03671228 ! negative regulation of adenylate cyclase activity GO:0007194 16 16 1,000 3,944E-03 0,04060798 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! segmentation GO:0035282 17 16 1,000 3,944E-03 0,04038238 ! microtubule cytoskeleton organization GO:0000226 55 55 2,000 4,157E-03 0,04233282 ! regulation of cell adhesion GO:0030155 56 55 2,000 4,157E-03 0,04210022 ! extracellular structure organization GO:0043062 56 56 2,000 4,375E-03 0,04405846 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 1,000 4,453E-03 0,0446034 ! positive regulation of cell adhesion GO:0045785 17 17 1,000 4,453E-03 0,0443623 ! myelination GO:0042552 17 17 1,000 4,453E-03 0,04412379 ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 4,453E-03 0,04388783 ! regulation of binding GO:0051098 60 57 2,000 4,599E-03 0,04508339 ! regulation of cell projection organization GO:0031344 19 18 1,000 4,991E-03 0,0486677 ! regulation of cellular catabolic process GO:0031329 18 18 1,000 4,991E-03 0,04841155 ! meiosis I GO:0007127 18 18 1,000 4,991E-03 0,04815809 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 1,000 4,991E-03 0,04790726 ! negative regulation of DNA binding GO:0043392 19 18 1,000 4,991E-03 0,04765904 ! telencephalon development GO:0021537 19 18 1,000 4,991E-03 0,04741337 ! ensheathment of neurons GO:0007272 18 18 1,000 4,991E-03 0,04717023 GO:0008366|axon ensheathment, ! negative regulation of catabolic process GO:0009895 18 18 1,000 4,991E-03 0,04692956 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 1,000 4,991E-03 0,04669134 ! protein polymerization GO:0051258 65 60 2,000 5,312E-03 0,04944877 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 5,557E-03 0,05146585 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 1,000 5,557E-03 0,05120852 ! peripheral nervous system development GO:0007422 19 19 1,000 5,557E-03 0,05095375 ! regulation of protein stability GO:0031647 19 19 1,000 5,557E-03 0,0507015 ! regulation of cell shape GO:0008360 21 19 1,000 5,557E-03 0,05045174 ! response to heat GO:0009408 19 19 1,000 5,557E-03 0,05020443 ! regulation of cellular component biogenesis GO:0044087 63 62 2,000 5,823E-03 0,05235245 ! negative regulation of cellular component organization GO:0051129 65 63 2,000 6,089E-03 0,05447884 ! negative regulation of cell adhesion GO:0007162 21 20 1,000 6,151E-03 0,05476775 ! establishment or maintenance of cell polarity GO:0007163 21 20 1,000 6,151E-03 0,05450444 ! negative regulation of binding GO:0051100 21 20 1,000 6,151E-03 0,05424366 ! nucleus organization GO:0006997 20 20 1,000 6,151E-03 0,05398535 ! detection of abiotic stimulus GO:0009582 21 20 1,000 6,151E-03 0,0537295 ! peptidyl-tyrosine modification GO:0018212 21 20 1,000 6,151E-03 0,05347606 ! angiogenesis GO:0001525 65 64 2,000 6,363E-03 0,05505297 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 1,000 6,773E-03 0,05833287 ! mammary gland development GO:0030879 23 21 1,000 6,773E-03 0,05806155 ! regulation of action potential in neuron GO:0019228 21 21 1,000 6,773E-03 0,05779275 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 6,773E-03 0,05752642 ! DNA packaging GO:0006323 66 66 2,000 6,931E-03 0,05859497 ! negative regulation of protein metabolic process GO:0051248 66 66 2,000 6,931E-03 0,05832741 ! striated muscle tissue development GO:0014706 69 67 2,000 7,226E-03 0,0605348 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 7,423E-03 0,06190052 GO:0090047|positive regulation of transcription regulator activity, ! positive regulation of DNA metabolic process GO:0051054 23 22 1,000 7,423E-03 0,06162169 ! maintenance of protein location in cell GO:0032507 23 22 1,000 7,423E-03 0,06134536 ! ovulation cycle process GO:0022602 22 22 1,000 7,423E-03 0,0610715 ! spindle organization GO:0007051 22 22 1,000 7,423E-03 0,06080007 ! detection of external stimulus GO:0009581 23 22 1,000 7,423E-03 0,06053104 ! neuron migration GO:0001764 22 22 1,000 7,423E-03 0,06026439 ! response to radiation GO:0009314 70 68 2,000 7,529E-03 0,06085623 ! response to estrogen stimulus GO:0043627 23 23 1,000 8,099E-03 0,06518191 ! positive regulation of growth GO:0045927 23 23 1,000 8,099E-03 0,06489851 ! female gonad development GO:0008585 23 23 1,000 8,099E-03 0,06461756 ! calcium-mediated signaling GO:0019722 23 23 1,000 8,099E-03 0,06433904 ! cell projection assembly GO:0030031 25 23 1,000 8,099E-03 0,0640629 ! muscle tissue development GO:0060537 72 70 2,000 8,156E-03 0,06423719 ! regulation of action potential GO:0001508 24 24 1,000 8,802E-03 0,06903213 ! gliogenesis GO:0042063 24 24 1,000 8,802E-03 0,06873962 ! glucose homeostasis GO:0042593 24 24 1,000 8,802E-03 0,06844958 GO:0033500|carbohydrate homeostasis, ! ovulation cycle GO:0042698 24 24 1,000 8,802E-03 0,06816198 ! maintenance of protein location GO:0045185 25 24 1,000 8,802E-03 0,06787678 ! glucan metabolic process GO:0044042 25 24 1,000 8,802E-03 0,06759396 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! regulation of gene-specific transcription GO:0032583 25 25 1,000 9,532E-03 0,07289251 ! endosome transport GO:0016197 25 25 1,000 9,532E-03 0,0725913 ! development of primary female sexual characteristics GO:0046545 25 25 1,000 9,532E-03 0,07229257 GO:0046660|female sex differentiation, ! regulation of T cell proliferation GO:0042129 25 25 1,000 9,532E-03 0,07199629 ! positive regulation of DNA binding GO:0043388 26 25 1,000 9,532E-03 0,07170243 ! heart morphogenesis GO:0003007 25 25 1,000 9,532E-03 0,07141096 ! negative regulation of immune system process GO:0002683 25 25 1,000 9,532E-03 0,07112184 ! positive regulation of binding GO:0051099 27 26 1,000 0,01028741 0,07645038 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 1,000 0,01028741 0,07614335 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01028741 0,07583878 ! double-strand break repair GO:0006302 27 26 1,000 0,01028741 0,07553663 ! response to insulin stimulus GO:0032868 28 26 1,000 0,01028741 0,07523688 ! maintenance of location in cell GO:0051651 27 26 1,000 0,01028741 0,07493951 ! synapse organization GO:0050808 26 26 1,000 0,01028741 0,07464447 ! cell morphogenesis involved in differentiation GO:0000904 82 77 2,000 0,0105905 0,07654234 ! regulation of protein modification process GO:0031399 79 78 2,000 0,01096907 0,07896874 ! microtubule-based movement GO:0007018 82 78 2,000 0,01096907 0,07866147 ! energy reserve metabolic process GO:0006112 28 27 1,000 0,01106878 0,07906883 ! cAMP-mediated signaling GO:0019933 27 27 1,000 0,01106878 0,07876354 ! mesenchymal cell development GO:0014031 29 27 1,000 0,01106878 0,0784606 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! cell growth GO:0016049 27 27 1,000 0,01106878 0,07815999 ! histone modification GO:0016570 28 28 1,000 0,01187558 0,08353701 ! regulation of mast cell proliferation GO:0070666 28 28 1,000 0,01187558 0,08321938 ! positive regulation of cell cycle GO:0045787 29 29 1,000 0,0127075 0,08871186 ! viral reproductive process GO:0022415 29 29 1,000 0,0127075 0,08837709 ! branching morphogenesis of a tube GO:0048754 29 29 1,000 0,0127075 0,08804485 ! regulation of lymphocyte proliferation GO:0050670 29 29 1,000 0,0127075 0,08771509 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! covalent chromatin modification GO:0016569 29 29 1,000 0,0127075 0,0873878 ! response to UV GO:0009411 29 29 1,000 0,0127075 0,08706294 ! blood vessel morphogenesis GO:0048514 84 83 2,000 0,01297935 0,08859605 ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,01356423 0,0922468 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 0,01356423 0,09190766 ! response to temperature stimulus GO:0009266 30 30 1,000 0,01356423 0,091571 ! vascular process in circulatory system GO:0003018 31 30 1,000 0,01356423 0,0912368 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 2,000 0,01428037 0,09570448 ! regulation of translational initiation GO:0006446 31 31 1,000 0,01444546 0,09646008 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,01444546 0,09611185 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,01444546 0,09576612 ! extracellular matrix organization GO:0030198 31 31 1,000 0,01444546 0,09542287 ! male gamete generation GO:0048232 90 88 2,000 0,01518762 0,09996711 GO:0007283|spermatogenesis, ! muscle fiber development GO:0048747 32 32 1,000 0,01535087 0,10068207 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,01535087 0,10032504 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 1,000 0,01535087 0,09997054 ! morphogenesis of a branching structure GO:0001763 32 32 1,000 0,01535087 0,09961853 ! regulation of lymphocyte differentiation GO:0045619 32 32 1,000 0,01535087 0,09926899 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,01535087 0,09892189 ! maintenance of location GO:0051235 33 32 1,000 0,01535087 0,09857722 ! regulation of protein complex assembly GO:0043254 33 33 1,000 0,01628017 0,10418181 ! regulation of angiogenesis GO:0045765 35 34 1,000 0,01723305 0,10989799 ! regulation of bone remodeling GO:0046850 34 34 1,000 0,01723305 0,10951903 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 0,01723305 0,10914268 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 0,01723305 0,1087689 ! response to peptide hormone stimulus GO:0043434 36 34 1,000 0,01723305 0,10839768 ! viral reproduction GO:0016032 34 34 1,000 0,01723305 0,10802898 ! detection of stimulus GO:0051606 36 34 1,000 0,01723305 0,10766278 ! blood vessel development GO:0001568 95 94 2,000 0,0181024 0,11271188 ! multicellular organism reproduction GO:0032504 36 35 1,000 0,01820922 0,11299525 GO:0048609|reproductive process in a multicellular organism, ! regulation of cell morphogenesis GO:0022604 38 35 1,000 0,01820922 0,11261607 ! positive regulation of phosphorylation GO:0042327 35 35 1,000 0,01820922 0,11223943 ! regulation of tissue remodeling GO:0034103 35 35 1,000 0,01820922 0,1118653 ! response to steroid hormone stimulus GO:0048545 35 35 1,000 0,01820922 0,11149365 ! vasculature development GO:0001944 97 96 2,000 0,01913869 0,11679673 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 1,000 0,01920837 0,11683505 GO:0045937|positive regulation of phosphate metabolic process, ! gonad development GO:0008406 36 36 1,000 0,01920837 0,11645073 ! regulation of lipase activity GO:0060191 36 36 1,000 0,01920837 0,11606892 ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 0,02023021 0,12184402 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! negative regulation of protein kinase activity GO:0006469 37 37 1,000 0,02023021 0,12144714 ! adaptive immune response GO:0002250 37 37 1,000 0,02023021 0,12105283 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! negative regulation of kinase activity GO:0033673 38 38 1,000 0,02127445 0,12688933 ! chromosome segregation GO:0007059 38 38 1,000 0,02127445 0,12648001 ! urogenital system development GO:0001655 38 38 1,000 0,02127445 0,12607332 ! axon guidance GO:0007411 39 38 1,000 0,02127445 0,12566924 ! regulation of homeostatic process GO:0032844 38 38 1,000 0,02127445 0,12526774 ! response to hormone stimulus GO:0009725 102 100 2,000 0,02130883 0,1250706 ! muscle organ development GO:0007517 102 100 2,000 0,02130883 0,12467355 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 2,000 0,02130883 0,12427901 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 0,02234079 0,1298867 ! activation of MAPK activity GO:0000187 39 39 1,000 0,02234079 0,12947825 ! response to unfolded protein GO:0006986 39 39 1,000 0,02234079 0,12907236 ! nucleotide-excision repair GO:0006289 40 39 1,000 0,02234079 0,12866901 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 0,02342896 0,13451583 ! negative regulation of transferase activity GO:0051348 40 40 1,000 0,02342896 0,13409808 ! myeloid cell differentiation GO:0030099 42 40 1,000 0,02342896 0,13368291 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,02453867 0,13958264 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! regulation of caspase activity GO:0043281 41 41 1,000 0,02453867 0,13915315 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,02566964 0,14512007 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,02566964 0,14467628 ! development of primary sexual characteristics GO:0045137 42 42 1,000 0,02566964 0,1442352 ! protein ubiquitination GO:0016567 43 42 1,000 0,02566964 0,14379679 ! response to protein stimulus GO:0051789 42 42 1,000 0,02566964 0,14336104 ! forebrain development GO:0030900 43 42 1,000 0,02566964 0,14292793 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,02566964 0,14249742 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 1,000 0,02682158 0,14844497 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,02682158 0,14800052 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 0,02799422 0,15401001 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,02918729 0,16009576 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 0,02918729 0,1596207 ! protein processing GO:0016485 45 45 1,000 0,02918729 0,15914845 ! rRNA transcription GO:0009303 5 5 0,000 0,02945195 0,16011783 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,02945195 0,15964689 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,02945195 0,15917872 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,02945195 0,15871328 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,02945195 0,15825056 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,02945195 0,15779053 ! reproductive cellular process GO:0048610 5 5 0,000 0,02945195 0,15733317 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,02945195 0,15687845 ! metencephalon development GO:0022037 5 5 0,000 0,02945195 0,15642635 ! water transport GO:0006833 5 5 0,000 0,02945195 0,15597685 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,02945195 0,15552992 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,02945195 0,15508555 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,02945195 0,15464371 ! glycerol metabolic process GO:0006071 5 5 0,000 0,02945195 0,15420438 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,02945195 0,15376754 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,02945195 0,15333317 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,02945195 0,15290125 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,02945195 0,15247175 GO:0010469|regulation of receptor activity, ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 0,000 0,02945195 0,15204466 ! CTP metabolic process GO:0046036 5 5 0,000 0,02945195 0,15161995 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,02945195 0,15119761 ! GTP metabolic process GO:0046039 5 5 0,000 0,02945195 0,15077762 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,02945195 0,15035995 ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,02945195 0,14994459 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,02945195 0,14953152 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,02945195 0,14912072 ! social behavior GO:0035176 5 5 0,000 0,02945195 0,14871217 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,02945195 0,14830586 ! 2-oxoglutarate metabolic process GO:0006103 5 5 0,000 0,02945195 0,14790175 ! memory GO:0007613 5 5 0,000 0,02945195 0,14749985 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,02945195 0,14710012 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,02945195 0,14670255 ! response to lipid GO:0033993 5 5 0,000 0,02945195 0,14630712 ! erythrocyte maturation GO:0043249 5 5 0,000 0,02945195 0,14591383 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,02945195 0,14552264 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,02945195 0,14513354 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,02945195 0,14474652 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,02945195 0,14436155 ! mechanosensory behavior GO:0007638 5 5 0,000 0,02945195 0,14397863 ! heart looping GO:0001947 5 5 0,000 0,02945195 0,14359773 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,02945195 0,14321885 ! response to interferon-gamma GO:0034341 5 5 0,000 0,02945195 0,14284196 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,02945195 0,14246704 ! endocrine pancreas development GO:0031018 5 5 0,000 0,02945195 0,14209409 ! pH reduction GO:0045851 5 5 0,000 0,02945195 0,14172309 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,02945195 0,14135402 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,02945195 0,14098687 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,02945195 0,14062161 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,02945195 0,14025825 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,02945195 0,13989676 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,02945195 0,13953713 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 0,000 0,02945195 0,13917934 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,02945195 0,13882338 ! adrenal gland development GO:0030325 5 5 0,000 0,02945195 0,13846924 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,02945195 0,1381169 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,02945195 0,13776635 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,02945195 0,13741758 ! astrocyte differentiation GO:0048708 5 5 0,000 0,02945195 0,13707056 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,02945195 0,1367253 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,02945195 0,13638177 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,02945195 0,13603996 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,02945195 0,13569986 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,02945195 0,13536145 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,02945195 0,13502473 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,02945195 0,13468969 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,02945195 0,1343563 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,02945195 0,13402455 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,02945195 0,13369444 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,02945195 0,13336595 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,02945195 0,13303908 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,02945195 0,1327138 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,02945195 0,13239011 ! response to ATP GO:0033198 5 5 0,000 0,02945195 0,13206799 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,02945195 0,13174743 ! regulation of appetite GO:0032098 5 5 0,000 0,02945195 0,13142843 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,02945195 0,13111097 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,02945195 0,13079504 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,02945195 0,13048063 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,02945195 0,13016773 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02945195 0,12985632 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,02945195 0,1295464 ! fear response GO:0042596 5 5 0,000 0,02945195 0,12923796 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,02945195 0,12893098 ! retinol metabolic process GO:0042572 5 5 0,000 0,02945195 0,12862546 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,02945195 0,12832138 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,02945195 0,12801873 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,02945195 0,12771751 ! parturition GO:0007567 5 5 0,000 0,02945195 0,12741771 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,02945195 0,1271193 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,02945195 0,1268223 ! Schwann cell differentiation GO:0014037 5 5 0,000 0,02945195 0,12652667 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,02945195 0,12623243 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,02945195 0,12593954 ! regulation of gliogenesis GO:0014013 5 5 0,000 0,02945195 0,12564802 GO:0045685|regulation of glial cell differentiation, ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,02945195 0,12535784 ! response to UV-B GO:0010224 5 5 0,000 0,02945195 0,12506899 ! oligodendrocyte development GO:0014003 5 5 0,000 0,02945195 0,12478148 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,02945195 0,12449528 ! activated T cell proliferation GO:0050798 5 5 0,000 0,02945195 0,1242104 ! interaction with symbiont GO:0051702 5 5 0,000 0,02945195 0,12392681 ! cellular extravasation GO:0045123 5 5 0,000 0,02945195 0,12364452 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,02945195 0,12336351 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,02945195 0,12308377 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,02945195 0,1228053 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,02945195 0,12252809 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,02945195 0,12225212 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,02945195 0,1219774 ! response to amine stimulus GO:0014075 5 5 0,000 0,02945195 0,12170391 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,02945195 0,12143164 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,02945195 0,12116059 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,02945195 0,12089074 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,02945195 0,1206221 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,02945195 0,12035464 ! neuron recognition GO:0008038 5 5 0,000 0,02945195 0,12008837 ! decidualization GO:0046697 5 5 0,000 0,02945195 0,11982327 ! hair follicle maturation GO:0048820 5 5 0,000 0,02945195 0,11955935 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,02945195 0,11929658 ! regulation of mitochondrial membrane potential GO:0051881 5 5 0,000 0,02945195 0,11903496 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,02945195 0,11877449 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,02945195 0,11851516 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,02945195 0,11825696 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,02945195 0,11799988 ! postreplication repair GO:0006301 5 5 0,000 0,02945195 0,11774391 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,02945195 0,11748905 GO:0021517|ventral spinal cord development, ! cellular pigmentation GO:0033059 5 5 0,000 0,02945195 0,1172353 ! histone methylation GO:0016571 5 5 0,000 0,02945195 0,11698264 ! DNA methylation GO:0006306 5 5 0,000 0,02945195 0,11673106 GO:0006305|DNA alkylation, ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02945195 0,11648056 ! T cell lineage commitment GO:0002360 5 5 0,000 0,02945195 0,11623114 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,02945195 0,11598278 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,02945195 0,11573549 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,02945195 0,11548924 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,02945195 0,11524404 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,02945195 0,11499988 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,02945195 0,11475675 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,02945195 0,11451465 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,02945195 0,11427356 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,02945195 0,11403349 ! sterol catabolic process GO:0016127 5 5 0,000 0,02945195 0,11379443 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,02945195 0,11355637 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,02945195 0,1133193 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,02945195 0,11308321 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,02945195 0,11284811 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,02945195 0,11261399 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,02945195 0,11238083 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,02945195 0,11214864 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,02945195 0,11191741 ! negative regulation of neuroblast proliferation GO:0007406 5 5 0,000 0,02945195 0,11168713 ! nucleosome positioning GO:0016584 5 5 0,000 0,02945195 0,11145779 ! regulation of isotype switching GO:0045191 5 5 0,000 0,02945195 0,11122939 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 0,000 0,02945195 0,11100193 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,02945195 0,11077539 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,02945195 0,11054978 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,02945195 0,11032509 ! NADPH regeneration GO:0006740 5 5 0,000 0,02945195 0,1101013 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,02945195 0,10987843 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,02945195 0,10965645 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,02945195 0,10943537 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,02945195 0,10921518 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,02945195 0,10899587 ! sarcomere organization GO:0045214 5 5 0,000 0,02945195 0,10877744 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,02945195 0,10855989 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,02945195 0,1083432 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,02945195 0,10812738 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,02945195 0,10791241 GO:0045622|regulation of T-helper cell differentiation, ! oocyte differentiation GO:0009994 5 5 0,000 0,02945195 0,1076983 GO:0048599|oocyte development, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,02945195 0,10748504 ! regulation of protein homodimerization activity GO:0043496 6 5 0,000 0,02945195 0,10727261 ! spleen development GO:0048536 5 5 0,000 0,02945195 0,10706103 ! male genitalia development GO:0030539 5 5 0,000 0,02945195 0,10685028 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,02945195 0,10664036 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,02945195 0,10643126 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,02945195 0,10622298 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,02945195 0,10601551 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,02945195 0,10580886 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,02945195 0,105603 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,02945195 0,10539795 ! regulation of Rac protein signal transduction GO:0035020 5 5 0,000 0,02945195 0,10519369 ! ATP catabolic process GO:0006200 5 5 0,000 0,02945195 0,10499022 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02945195 0,10478754 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,02945195 0,10458563 ! blastocyst formation GO:0001825 5 5 0,000 0,02945195 0,10438451 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,02945195 0,10418415 ! embryonic gut development GO:0048566 5 5 0,000 0,02945195 0,10398457 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,02945195 0,10378574 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,02945195 0,10358768 ! activation of innate immune response GO:0002218 5 5 0,000 0,02945195 0,10339037 GO:0002758|innate immune response-activating signal transduction, ! catecholamine transport GO:0051937 5 5 0,000 0,02945195 0,10319381 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,02945195 0,10299799 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,02945195 0,10280292 ! muscle adaptation GO:0043500 5 5 0,000 0,02945195 0,10260859 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,02945195 0,10241499 ! embryonic heart tube development GO:0035050 5 5 0,000 0,02945195 0,10222212 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,02945195 0,10202997 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,02945195 0,10183854 ! defense response to fungus GO:0050832 5 5 0,000 0,02945195 0,10164783 ! lysogeny GO:0030069 5 5 0,000 0,02945195 0,10145784 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,02945195 0,10126855 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,02945195 0,10107997 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,02945195 0,10089209 ! response to nicotine GO:0035094 5 5 0,000 0,02945195 0,1007049 ! establishment of cell polarity GO:0030010 5 5 0,000 0,02945195 0,10051841 ! mitochondrion localization GO:0051646 5 5 0,000 0,02945195 0,10033261 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,02945195 0,1001475 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 1,000 0,03040051 0,10318258 ! tube morphogenesis GO:0035239 47 46 1,000 0,03040051 0,1029929 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,03040051 0,10280393 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 0,03040051 0,10261564 ! positive regulation of ligase activity GO:0051351 47 46 1,000 0,03040051 0,10242804 ! cellular response to hormone stimulus GO:0032870 48 46 1,000 0,03040051 0,10224113 ! regulation of membrane potential GO:0042391 46 46 1,000 0,03040051 0,1020549 ! rhythmic process GO:0048511 47 47 1,000 0,03163361 0,10600136 ! actin filament organization GO:0007015 50 48 1,000 0,03288633 0,10999911 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 0,03288633 0,10979984 ! DNA recombination GO:0006310 48 48 1,000 0,03288633 0,10960128 ! leukocyte differentiation GO:0002521 50 49 1,000 0,0341584 0,11363526 ! cell cycle arrest GO:0007050 49 49 1,000 0,0341584 0,11343051 ! regulation of ligase activity GO:0051340 50 49 1,000 0,0341584 0,1132265 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 0,000 0,03523995 0,11660183 ! axon extension GO:0048675 7 6 0,000 0,03523995 0,11639287 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,03523995 0,11618465 ! tRNA modification GO:0006400 6 6 0,000 0,03523995 0,11597718 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,03523995 0,11577044 GO:0016446|somatic hypermutation of immunoglobulin genes, ! 'de novo' posttranslational protein folding GO:0051084 6 6 0,000 0,03523995 0,11556445 ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,03523995 0,11535918 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,03523995 0,11515464 ! regulation of S phase GO:0033261 6 6 0,000 0,03523995 0,11495083 ! myotube differentiation GO:0014902 6 6 0,000 0,03523995 0,11474774 ! regulation of B cell proliferation GO:0030888 6 6 0,000 0,03523995 0,11454536 ! bone remodeling GO:0046849 6 6 0,000 0,03523995 0,1143437 ! N-glycan processing GO:0006491 6 6 0,000 0,03523995 0,11414274 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,03523995 0,11394249 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,03523995 0,11374294 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,03523995 0,11354409 ! RNA methylation GO:0001510 6 6 0,000 0,03523995 0,11334593 ! cartilage condensation GO:0001502 7 6 0,000 0,03523995 0,11314847 ! regulation of activated T cell proliferation GO:0046006 6 6 0,000 0,03523995 0,11295169 ! succinate metabolic process GO:0006105 7 6 0,000 0,03523995 0,11275559 ! artery development GO:0060840 6 6 0,000 0,03523995 0,11256017 GO:0048844|artery morphogenesis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,03523995 0,11236543 ! bile acid metabolic process GO:0008206 6 6 0,000 0,03523995 0,11217136 ! androgen metabolic process GO:0008209 6 6 0,000 0,03523995 0,11197796 ! estrogen metabolic process GO:0008210 6 6 0,000 0,03523995 0,11178523 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,03523995 0,11159316 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,03523995 0,11140175 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,03523995 0,11121099 ! pathogenesis GO:0009405 6 6 0,000 0,03523995 0,11102089 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,03523995 0,11083143 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,03523995 0,11064262 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,03523995 0,11045445 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,03523995 0,11026693 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,03523995 0,11008003 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,03523995 0,10989377 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,03523995 0,10970814 ! arginine metabolic process GO:0006525 6 6 0,000 0,03523995 0,10952314 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,03523995 0,10933875 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,03523995 0,10915499 ! glutamate catabolic process GO:0006538 7 6 0,000 0,03523995 0,10897184 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,03523995 0,10878931 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,03523995 0,10860739 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,03523995 0,10842608 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,03523995 0,10824537 ! V(D)J recombination GO:0033151 6 6 0,000 0,03523995 0,10806526 ! focal adhesion formation GO:0048041 7 6 0,000 0,03523995 0,10788575 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,03523995 0,10770683 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,03523995 0,10752851 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,03523995 0,10735078 ! regulation of heart rate GO:0002027 6 6 0,000 0,03523995 0,10717363 ! lipid digestion GO:0044241 6 6 0,000 0,03523995 0,10699707 ! asymmetric protein localization GO:0008105 6 6 0,000 0,03523995 0,10682108 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,03523995 0,10664568 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,03523995 0,10647085 ! Rac protein signal transduction GO:0016601 6 6 0,000 0,03523995 0,10629659 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,03523995 0,10612291 ! ruffle organization GO:0031529 6 6 0,000 0,03523995 0,10594979 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,03523995 0,10577723 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,03523995 0,10560523 ! neutral amino acid transport GO:0015804 6 6 0,000 0,03523995 0,1054338 ! L-amino acid transport GO:0015807 6 6 0,000 0,03523995 0,10526292 ! bone mineralization GO:0030282 6 6 0,000 0,03523995 0,10509259 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,03523995 0,10492281 ! negative regulation of ossification GO:0030279 6 6 0,000 0,03523995 0,10475358 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,03523995 0,10458489 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,03523995 0,10441675 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,03523995 0,10424915 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,03523995 0,10408208 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,03523995 0,10391555 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,03523995 0,10374955 ! regulation of organ growth GO:0046620 6 6 0,000 0,03523995 0,10358408 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,03523995 0,10341914 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,03523995 0,10325472 ! response to dsRNA GO:0043331 6 6 0,000 0,03523995 0,10309082 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,03523995 0,10292745 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,03523995 0,10276459 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,03523995 0,10260224 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,03523995 0,10244041 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,03523995 0,10227909 ! positive regulation of B cell differentiation GO:0045579 6 6 0,000 0,03523995 0,10211827 ! multicellular organismal aging GO:0010259 6 6 0,000 0,03523995 0,10195796 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,03523995 0,10179815 ! erythrocyte development GO:0048821 6 6 0,000 0,03523995 0,10163884 ! renal water homeostasis GO:0003091 6 6 0,000 0,03523995 0,10148003 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,03523995 0,10132171 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,03523995 0,10116389 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,03523995 0,10100656 ! ribosome assembly GO:0042255 6 6 0,000 0,03523995 0,10084972 ! positive regulation of Ras GTPase activity GO:0032320 6 6 0,000 0,03523995 0,10069336 ! diencephalon development GO:0021536 6 6 0,000 0,03523995 0,10053749 ! fucose catabolic process GO:0019317 6 6 0,000 0,03523995 0,1003821 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,03523995 0,10022719 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,03523995 0,10007276 ! regulation of lipid transport GO:0032368 6 6 0,000 0,03523995 0,0999188 ! regulation of cell division GO:0051302 6 6 0,000 0,03523995 0,09976531 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,03523995 0,0996123 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,03523995 0,09945975 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,03523995 0,09930767 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,03523995 0,09915606 ! neuroblast proliferation GO:0007405 6 6 0,000 0,03523995 0,09900491 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,03523995 0,09885421 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,03523995 0,09870398 ! regulation of glucose transport GO:0010827 6 6 0,000 0,03523995 0,0985542 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,03523995 0,09840488 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,03523995 0,098256 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,03523995 0,09810758 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,03523995 0,09795961 ! thymus development GO:0048538 6 6 0,000 0,03523995 0,09781208 ! lymph node development GO:0048535 6 6 0,000 0,03523995 0,09766499 ! organic cation transport GO:0015695 6 6 0,000 0,03523995 0,09751835 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,03523995 0,09737214 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,03523995 0,09722638 ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,03523995 0,09708105 ! sperm-egg recognition GO:0035036 7 6 0,000 0,03523995 0,09693615 GO:0007339|binding of sperm to zona pellucida, ! germ cell migration GO:0008354 6 6 0,000 0,03523995 0,09679168 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 0,000 0,03523995 0,09664765 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,03523995 0,09650404 ! alditol metabolic process GO:0019400 6 6 0,000 0,03523995 0,09636086 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 0,000 0,03523995 0,0962181 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,03523995 0,09607577 ! maternal placenta development GO:0001893 6 6 0,000 0,03523995 0,09593385 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,03523995 0,09579236 ! chromatin assembly GO:0031497 50 50 1,000 0,03544956 0,09622023 GO:0006334|nucleosome assembly, ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,03544956 0,09607873 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,03544956 0,09593764 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,03544956 0,09579697 ! protein modification by small protein conjugation GO:0032446 52 51 1,000 0,03675954 0,09919156 ! protein-DNA complex assembly GO:0065004 51 51 1,000 0,03675954 0,09904654 ! interphase of mitotic cell cycle GO:0051329 52 51 1,000 0,03675954 0,09890195 GO:0051325|interphase, ! protein maturation GO:0051604 51 51 1,000 0,03675954 0,09875777 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,03808809 0,1021781 ! regulation of T cell activation GO:0050863 53 53 1,000 0,03943496 0,10563754 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,04079988 0,10913524 ! respiratory burst GO:0045730 7 7 0,000 0,04099426 0,10949626 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 0,000 0,04099426 0,1093378 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 0,000 0,04099426 0,1091798 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,04099426 0,10902225 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,04099426 0,10886516 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,04099426 0,10870852 ! regulation of chemokine production GO:0032642 7 7 0,000 0,04099426 0,10855233 ! positive regulation of GTPase activity GO:0043547 7 7 0,000 0,04099426 0,10839659 ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,04099426 0,10824129 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,04099426 0,10808644 GO:0043241|protein complex disassembly, ! hair follicle morphogenesis GO:0031069 7 7 0,000 0,04099426 0,10793203 ! gene silencing by RNA GO:0031047 7 7 0,000 0,04099426 0,10777806 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,04099426 0,10762453 ! oxaloacetate metabolic process GO:0006107 7 7 0,000 0,04099426 0,10747144 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,04099426 0,10731878 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,04099426 0,10716656 ! axis specification GO:0009798 7 7 0,000 0,04099426 0,10701476 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,04099426 0,1068634 ! visual behavior GO:0007632 7 7 0,000 0,04099426 0,10671246 GO:0008542|visual learning, ! startle response GO:0001964 7 7 0,000 0,04099426 0,10656195 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,04099426 0,10641186 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,04099426 0,1062622 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,04099426 0,10611295 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,04099426 0,10596413 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,04099426 0,10581572 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,04099426 0,10566772 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,04099426 0,10552014 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 0,000 0,04099426 0,10537297 ! digestive system development GO:0055123 7 7 0,000 0,04099426 0,10522621 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,04099426 0,10507986 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,04099426 0,10493392 ! protein targeting to ER GO:0045047 8 7 0,000 0,04099426 0,10478838 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,04099426 0,10464324 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 0,000 0,04099426 0,10449851 ! endoderm development GO:0007492 7 7 0,000 0,04099426 0,10435417 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,04099426 0,10421024 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,04099426 0,1040667 GO:0006688|glycosphingolipid biosynthetic process, ! response to hexose stimulus GO:0009746 7 7 0,000 0,04099426 0,10392355 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,04099426 0,1037808 GO:0033619|membrane protein proteolysis, ! positive regulation of survival gene product expression GO:0045885 7 7 0,000 0,04099426 0,10363844 ! regulation of skeletal muscle fiber development GO:0048742 7 7 0,000 0,04099426 0,10349647 ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,04099426 0,10335489 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,04099426 0,10321369 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,04099426 0,10307288 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,04099426 0,10293245 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,04099426 0,10279241 ! response to X-ray GO:0010165 7 7 0,000 0,04099426 0,10265275 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,04099426 0,10251346 ! UV protection GO:0009650 7 7 0,000 0,04099426 0,10237456 ! DNA integration GO:0015074 7 7 0,000 0,04099426 0,10223602 ! myofibril assembly GO:0030239 7 7 0,000 0,04099426 0,10209787 GO:0055002|striated muscle cell development, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,04099426 0,10196008 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,04099426 0,10182267 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,04099426 0,10168563 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,04099426 0,10154895 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,04099426 0,10141265 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,04099426 0,10127671 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,04099426 0,10114113 GO:0019827|stem cell maintenance, ! alpha-beta T cell differentiation GO:0046632 7 7 0,000 0,04099426 0,10100591 ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,04099426 0,10087106 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 0,000 0,04099426 0,10073656 ! axon cargo transport GO:0008088 7 7 0,000 0,04099426 0,10060243 ! eating behavior GO:0042755 7 7 0,000 0,04099426 0,10046865 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,04099426 0,10033522 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,04099426 0,10020215 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,04099426 0,10006943 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,04099426 0,09993707 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,04099426 0,09980505 ! cranial nerve development GO:0021545 7 7 0,000 0,04099426 0,09967338 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,04099426 0,09954206 ! induction of an organ GO:0001759 7 7 0,000 0,04099426 0,09941108 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,04099426 0,09928045 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,04099426 0,09915016 ! autonomic nervous system development GO:0048483 7 7 0,000 0,04099426 0,09902021 ! intracellular lipid transport GO:0032365 7 7 0,000 0,04099426 0,0988906 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,04099426 0,09876134 ! platelet activation GO:0030168 8 7 0,000 0,04099426 0,0986324 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,04099426 0,09850381 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,04099426 0,09837555 ! natural killer cell activation GO:0030101 7 7 0,000 0,04099426 0,09824762 ! response to gamma radiation GO:0010332 8 7 0,000 0,04099426 0,09812003 ! NADP metabolic process GO:0006739 7 7 0,000 0,04099426 0,09799277 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,04099426 0,09786583 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,04099426 0,09773923 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,04099426 0,09761295 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,04099426 0,097487 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,04099426 0,09736137 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,04099426 0,09723606 ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,04099426 0,09711108 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,04099426 0,09698642 ! cell-cell recognition GO:0009988 8 7 0,000 0,04099426 0,09686208 ! hormone catabolic process GO:0042447 7 7 0,000 0,04099426 0,09673806 ! dopamine metabolic process GO:0042417 7 7 0,000 0,04099426 0,09661435 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,04099426 0,09649096 ! oxygen transport GO:0015671 7 7 0,000 0,04099426 0,09636789 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,04099426 0,09624512 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,04099426 0,09612267 ! regulation of axon extension GO:0030516 7 7 0,000 0,04099426 0,09600054 ! cell killing GO:0001906 7 7 0,000 0,04099426 0,09587871 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,04099426 0,09575719 ! adult feeding behavior GO:0008343 7 7 0,000 0,04099426 0,09563598 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,04099426 0,09551507 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,04099426 0,09539447 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,04099426 0,09527418 ! response to cold GO:0009409 7 7 0,000 0,04099426 0,09515418 ! nucleosome organization GO:0034728 55 55 1,000 0,04218261 0,09778938 ! protein modification by small protein conjugation or removal GO:0070647 56 55 1,000 0,04218261 0,09766653 ! regulation of skeletal muscle tissue development GO:0048641 8 8 0,000 0,04671509 0,10802497 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,04671509 0,1078896 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,04671509 0,10775457 ! positive regulation of translation GO:0045727 8 8 0,000 0,04671509 0,10761988 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,04671509 0,10748552 ! superoxide anion generation GO:0042554 8 8 0,000 0,04671509 0,1073515 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,04671509 0,10721781 ! cGMP metabolic process GO:0046068 8 8 0,000 0,04671509 0,10708446 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,04671509 0,10695143 ! 'de novo' protein folding GO:0006458 8 8 0,000 0,04671509 0,10681874 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,04671509 0,10668637 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,04671509 0,10655434 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,04671509 0,10642263 ! zinc ion transport GO:0006829 8 8 0,000 0,04671509 0,10629124 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,04671509 0,10616018 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,04671509 0,10602944 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 0,000 0,04671509 0,10589902 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,04671509 0,10576892 ! lipid localization GO:0010876 8 8 0,000 0,04671509 0,10563915 GO:0019915|lipid storage, ! response to pain GO:0048265 8 8 0,000 0,04671509 0,10550969 ! response to cAMP GO:0051591 8 8 0,000 0,04671509 0,10538054 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,04671509 0,10525172 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,04671509 0,1051232 ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 0,000 0,04671509 0,104995 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,04671509 0,10486712 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,04671509 0,10473954 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,04671509 0,10461228 ! sensory perception of taste GO:0050909 8 8 0,000 0,04671509 0,10448532 ! organelle fusion GO:0048284 8 8 0,000 0,04671509 0,10435867 ! pancreas development GO:0031016 8 8 0,000 0,04671509 0,10423233 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,04671509 0,10410629 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! T cell selection GO:0045058 8 8 0,000 0,04671509 0,10398056 ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,04671509 0,10385513 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,04671509 0,10373 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,04671509 0,10360518 ! sperm motility GO:0030317 8 8 0,000 0,04671509 0,10348065 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,04671509 0,10335643 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,04671509 0,1032325 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,04671509 0,10310887 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,04671509 0,10298553 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,04671509 0,10286249 GO:0031114|regulation of microtubule depolymerization, ! phosphagen metabolic process GO:0006599 8 8 0,000 0,04671509 0,10273974 GO:0006600|creatine metabolic process, ! polyamine metabolic process GO:0006595 8 8 0,000 0,04671509 0,10261729 ! Golgi organization GO:0007030 8 8 0,000 0,04671509 0,10249512 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,04671509 0,10237325 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,04671509 0,10225167 ! fructose metabolic process GO:0006000 8 8 0,000 0,04671509 0,10213037 ! mannose metabolic process GO:0006013 9 8 0,000 0,04671509 0,10200936 ! NAD metabolic process GO:0019674 8 8 0,000 0,04671509 0,10188864 ! negative regulation of mitotic cell cycle GO:0045930 9 8 0,000 0,04671509 0,10176821 ! plasma membrane fusion GO:0045026 8 8 0,000 0,04671509 0,10164806 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,04671509 0,10152819 ! response to fungus GO:0009620 8 8 0,000 0,04671509 0,1014086 ! stem cell differentiation GO:0048863 8 8 0,000 0,04671509 0,1012893 ! alpha-beta T cell activation GO:0046631 8 8 0,000 0,04671509 0,10117027 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,04671509 0,10105153 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,04671509 0,10093306 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,04671509 0,10081488 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,04671509 0,10069696 ! regulation of vasodilation GO:0042312 8 8 0,000 0,04671509 0,10057933 ! vasoconstriction GO:0042310 8 8 0,000 0,04671509 0,10046196 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,04671509 0,10034488 ! muscle cell development GO:0055001 8 8 0,000 0,04671509 0,10022806 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,04671509 0,10011152 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,04671509 0,09999524 ! sensory perception of pain GO:0019233 8 8 0,000 0,04671509 0,09987924 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,04671509 0,0997635 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,04671509 0,09964804 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,04671509 0,09953284 ! chromatin silencing GO:0006342 8 8 0,000 0,04671509 0,0994179 ! tissue regeneration GO:0042246 8 8 0,000 0,04671509 0,09930323 ! salivary gland development GO:0007431 8 8 0,000 0,04671509 0,09918883 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,04671509 0,09907469 ! T cell homeostasis GO:0043029 8 8 0,000 0,04671509 0,09896081 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,04671509 0,09884719 ! water homeostasis GO:0030104 8 8 0,000 0,04671509 0,09873383 ! cofactor transport GO:0051181 8 8 0,000 0,04671509 0,09862074 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,04671509 0,0985079 ! acid secretion GO:0046717 8 8 0,000 0,04671509 0,09839532 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,04671509 0,098283 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,04671509 0,09817093 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,04671509 0,09805912 ! branched chain family amino acid metabolic process GO:0009081 8 8 0,000 0,04671509 0,09794756 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,04671509 0,09783625 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,04671509 0,0977252 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,04671509 0,0976144 ! release of cytochrome c from mitochondria GO:0001836 9 8 0,000 0,04671509 0,09750385 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,04671509 0,09739356 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,04671509 0,09728351 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,04671509 0,09717371 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,04671509 0,09706415 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,04671509 0,09695485 ! developmental induction GO:0031128 8 8 0,000 0,04671509 0,09684579 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,04671509 0,09673697 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,04671509 0,0966284 ! actin filament polymerization GO:0030041 9 8 0,000 0,04671509 0,09652007 ! peptide hormone processing GO:0016486 8 8 0,000 0,04671509 0,09641199 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,04671509 0,09630414 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,04671509 0,09619654 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 1,000 0,04935474 0,10151874 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,05083917 0,1044555 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! regulation of protein amino acid phosphorylation GO:0001932 62 61 1,000 0,05083917 0,10433918 ! axonogenesis GO:0007409 66 62 1,000 0,0523397 0,10729929 ! regulation of lymphocyte activation GO:0051249 62 62 1,000 0,0523397 0,10718007 ! lactation GO:0007595 10 9 0,000 0,05240261 0,10718981 ! embryonic pattern specification GO:0009880 10 9 0,000 0,05240261 0,10707097 ! positive regulation of cell size GO:0045793 9 9 0,000 0,05240261 0,1069524 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,05240261 0,10683409 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,05240261 0,10671604 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,05240261 0,10659825 ! negative regulation of cell cycle process GO:0010948 9 9 0,000 0,05240261 0,10648072 ! viral genome replication GO:0019079 9 9 0,000 0,05240261 0,10636345 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,05240261 0,10624644 ! copper ion transport GO:0006825 9 9 0,000 0,05240261 0,10612969 ! lipid phosphorylation GO:0046834 9 9 0,000 0,05240261 0,10601319 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,05240261 0,10589695 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,05240261 0,10578096 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,05240261 0,10566522 ! RNA polyadenylation GO:0043631 9 9 0,000 0,05240261 0,10554974 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,05240261 0,10543451 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,05240261 0,10531954 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,05240261 0,10520481 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,05240261 0,10509033 ! phospholipid efflux GO:0033700 9 9 0,000 0,05240261 0,1049761 ! response to alkaloid GO:0043279 10 9 0,000 0,05240261 0,10486212 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,05240261 0,10474839 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,05240261 0,1046349 GO:0042107|cytokine metabolic process, ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,05240261 0,10452166 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 0,000 0,05240261 0,10440866 ! response to ethanol GO:0045471 9 9 0,000 0,05240261 0,10429591 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,05240261 0,1041834 ! activation of pro-apoptotic gene products GO:0008633 9 9 0,000 0,05240261 0,10407114 ! methionine metabolic process GO:0006555 9 9 0,000 0,05240261 0,10395911 ! glutamine metabolic process GO:0006541 9 9 0,000 0,05240261 0,10384733 ! response to osmotic stress GO:0006970 9 9 0,000 0,05240261 0,10373578 ! pigmentation during development GO:0048066 9 9 0,000 0,05240261 0,10362448 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,05240261 0,10351341 ! central nervous system neuron development GO:0021954 10 9 0,000 0,05240261 0,10340259 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,05240261 0,10329199 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,05240261 0,10318164 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,05240261 0,10307152 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,05240261 0,10296164 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,05240261 0,10285199 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 0,000 0,05240261 0,10274257 GO:0060675|ureteric bud morphogenesis, ! L-glutamate transport GO:0015813 9 9 0,000 0,05240261 0,10263338 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,05240261 0,10252443 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,05240261 0,10241571 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,05240261 0,10230722 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,05240261 0,10219896 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,05240261 0,10209092 ! negative regulation of protein import into nucleus GO:0042308 9 9 0,000 0,05240261 0,10198312 ! DNA replication initiation GO:0006270 9 9 0,000 0,05240261 0,10187554 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,05240261 0,10176819 GO:0006692|prostanoid metabolic process, ! T cell differentiation in the thymus GO:0033077 9 9 0,000 0,05240261 0,10166107 ! regulation of cellular pH GO:0030641 9 9 0,000 0,05240261 0,10155417 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 0,000 0,05240261 0,10144749 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,05240261 0,10134104 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,05240261 0,10123482 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,05240261 0,10112881 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,05240261 0,10102303 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,05240261 0,10091747 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,05240261 0,10081212 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,05240261 0,100707 ! collagen catabolic process GO:0030574 9 9 0,000 0,05240261 0,1006021 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,05240261 0,10049741 ! purine base metabolic process GO:0006144 9 9 0,000 0,05240261 0,10039295 ! gas transport GO:0015669 9 9 0,000 0,05240261 0,1002887 ! cholesterol efflux GO:0033344 9 9 0,000 0,05240261 0,10018466 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,05240261 0,10008084 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,05240261 0,09997724 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,05240261 0,09987385 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,05240261 0,09977068 ! defense response to virus GO:0051607 9 9 0,000 0,05240261 0,09966771 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,05240261 0,09956496 ! actin filament-based movement GO:0030048 9 9 0,000 0,05240261 0,09946243 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,05240261 0,0993601 ! glucose metabolic process GO:0006006 63 63 1,000 0,0538561 0,1020111 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,05538815 0,1048053 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,05538815 0,10469781 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,05693561 0,10751264 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,05805703 0,10951802 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,05805703 0,10940604 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,05805703 0,10929428 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,05805703 0,10918276 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,05805703 0,10907146 ! neuron maturation GO:0042551 10 10 0,000 0,05805703 0,10896039 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,05805703 0,10884955 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,05805703 0,10873893 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,05805703 0,10862853 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,05805703 0,10851836 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,05805703 0,10840841 ! hormone secretion GO:0046879 10 10 0,000 0,05805703 0,10829869 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,05805703 0,10818918 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,05805703 0,1080799 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,05805703 0,10797084 ! cAMP metabolic process GO:0046058 10 10 0,000 0,05805703 0,107862 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,05805703 0,10775338 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,05805703 0,10764497 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,05805703 0,10753679 ! glial cell development GO:0021782 10 10 0,000 0,05805703 0,10742882 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,05805703 0,10732107 ! apoptotic mitochondrial changes GO:0008637 11 10 0,000 0,05805703 0,10721353 ! fat cell differentiation GO:0045444 10 10 0,000 0,05805703 0,10710621 ! myoblast differentiation GO:0045445 10 10 0,000 0,05805703 0,1069991 ! centrosome cycle GO:0007098 10 10 0,000 0,05805703 0,10689221 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,05805703 0,10678553 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,05805703 0,10667907 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,05805703 0,10657281 ! regulation of survival gene product expression GO:0045884 10 10 0,000 0,05805703 0,10646677 ! induction of apoptosis via death domain receptors GO:0008625 10 10 0,000 0,05805703 0,10636094 ! epidermis morphogenesis GO:0048730 10 10 0,000 0,05805703 0,10625532 ! protein polyubiquitination GO:0000209 10 10 0,000 0,05805703 0,1061499 ! glutamate metabolic process GO:0006536 11 10 0,000 0,05805703 0,1060447 ! plasma membrane organization GO:0007009 10 10 0,000 0,05805703 0,10593971 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,05805703 0,10583492 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cell-substrate junction assembly GO:0007044 11 10 0,000 0,05805703 0,10573034 ! lysosomal transport GO:0007041 10 10 0,000 0,05805703 0,10562597 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,05805703 0,1055218 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,05805703 0,10541784 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,05805703 0,10531408 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,05805703 0,10521052 ! exocrine system development GO:0035272 10 10 0,000 0,05805703 0,10510717 ! cell structure disassembly during apoptosis GO:0006921 10 10 0,000 0,05805703 0,10500403 ! embryo implantation GO:0007566 11 10 0,000 0,05805703 0,10490108 ! regulation of protein binding GO:0043393 11 10 0,000 0,05805703 0,10479834 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,05805703 0,1046958 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,05805703 0,10459345 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,05805703 0,10449131 ! intermediate filament cytoskeleton organization GO:0045104 10 10 0,000 0,05805703 0,10438937 ! protein export from nucleus GO:0006611 10 10 0,000 0,05805703 0,10428763 ! negative regulation of immune response GO:0050777 10 10 0,000 0,05805703 0,10418608 ! cytolysis GO:0019835 10 10 0,000 0,05805703 0,10408473 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,05805703 0,10398358 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,05805703 0,10388263 ! regulation of B cell differentiation GO:0045577 10 10 0,000 0,05805703 0,10378187 ! histone deacetylation GO:0016575 10 10 0,000 0,05805703 0,1036813 ! mRNA splice site selection GO:0006376 11 10 0,000 0,05805703 0,10358093 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,05805703 0,10348076 ! gland morphogenesis GO:0022612 10 10 0,000 0,05805703 0,10338078 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,05805703 0,10328099 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,05805703 0,10318139 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,05805703 0,10308199 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,05805703 0,10298278 ! regulation of erythrocyte differentiation GO:0045646 10 10 0,000 0,05805703 0,10288375 ! regulation of epidermis development GO:0045682 10 10 0,000 0,05805703 0,10278492 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,05805703 0,10268628 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,05805703 0,10258783 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,05805703 0,10248956 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,05805703 0,10239149 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,05805703 0,1022936 ! lymphocyte homeostasis GO:0002260 10 10 0,000 0,05805703 0,1021959 ! nerve development GO:0021675 10 10 0,000 0,05805703 0,10209838 ! gut development GO:0048565 10 10 0,000 0,05805703 0,10200105 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,05805703 0,10190391 ! positive regulation of neuron apoptosis GO:0043525 10 10 0,000 0,05805703 0,10180695 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,05805703 0,10171017 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,05805703 0,10161358 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,05805703 0,10151718 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,05849826 0,10219174 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 1,000 0,06007586 0,10484831 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! Ras protein signal transduction GO:0007265 69 67 1,000 0,06007586 0,10474912 ! chromatin assembly or disassembly GO:0006333 68 68 1,000 0,0616682 0,10742391 ! regulation of cell size GO:0008361 68 68 1,000 0,0616682 0,10732248 ! regulation of translation GO:0006417 69 69 1,000 0,06327506 0,11001503 ! regionalization GO:0003002 70 69 1,000 0,06327506 0,10991134 ! regulation of leukocyte activation GO:0002694 69 69 1,000 0,06327506 0,10980785 ! protein secretion GO:0009306 11 11 0,000 0,06367852 0,11040406 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,06367852 0,1103003 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 0,000 0,06367852 0,11019673 ! negative regulation of defense response GO:0031348 11 11 0,000 0,06367852 0,11009336 ! G1 phase of mitotic cell cycle GO:0000080 12 11 0,000 0,06367852 0,10999017 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,06367852 0,10988719 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,06367852 0,10978439 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,06367852 0,10968179 ! skin development GO:0043588 11 11 0,000 0,06367852 0,10957938 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,06367852 0,10947716 ! microtubule-based transport GO:0010970 11 11 0,000 0,06367852 0,10937513 ! endothelial cell migration GO:0043542 11 11 0,000 0,06367852 0,10927329 ! peroxisomal transport GO:0043574 11 11 0,000 0,06367852 0,10917164 ! protein amino acid methylation GO:0006479 11 11 0,000 0,06367852 0,10907018 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,06367852 0,10896891 GO:0003015|heart process, ! dendrite development GO:0016358 11 11 0,000 0,06367852 0,10886783 ! T cell proliferation GO:0042098 11 11 0,000 0,06367852 0,10876693 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,06367852 0,10866622 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! negative regulation of endothelial cell proliferation GO:0001937 11 11 0,000 0,06367852 0,1085657 ! spinal cord development GO:0021510 11 11 0,000 0,06367852 0,10846536 ! activation of MAPKK activity GO:0000186 12 11 0,000 0,06367852 0,1083652 ! smooth muscle contraction GO:0006939 11 11 0,000 0,06367852 0,10826524 ! cellular response to starvation GO:0009267 11 11 0,000 0,06367852 0,10816545 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,06367852 0,10806585 ! digestive system process GO:0022600 11 11 0,000 0,06367852 0,10796644 ! mitotic spindle organization GO:0007052 11 11 0,000 0,06367852 0,1078672 ! fucose metabolic process GO:0006004 11 11 0,000 0,06367852 0,10776815 ! membrane budding GO:0006900 11 11 0,000 0,06367852 0,10766928 ! monoamine transport GO:0015844 11 11 0,000 0,06367852 0,10757059 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,06367852 0,10747208 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,06367852 0,10737376 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,06367852 0,10727561 ! body fluid secretion GO:0007589 11 11 0,000 0,06367852 0,10717764 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,06367852 0,10707985 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,06367852 0,10698224 ! intermediate filament-based process GO:0045103 11 11 0,000 0,06367852 0,10688481 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,06367852 0,10678755 GO:0060415|muscle tissue morphogenesis, ! membrane depolarization GO:0051899 11 11 0,000 0,06367852 0,10669047 ! regulation of interleukin-2 production GO:0032663 11 11 0,000 0,06367852 0,10659357 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,06367852 0,10649684 ! oogenesis GO:0048477 11 11 0,000 0,06367852 0,10640029 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,06367852 0,10630391 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,06367852 0,10620771 ! vitamin transport GO:0051180 11 11 0,000 0,06367852 0,10611168 ! muscle maintenance GO:0046716 12 11 0,000 0,06367852 0,10601582 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,06367852 0,10592014 ! hindbrain development GO:0030902 11 11 0,000 0,06367852 0,10582463 ! steroid catabolic process GO:0006706 11 11 0,000 0,06367852 0,10572929 ! endocrine process GO:0050886 11 11 0,000 0,06367852 0,10563413 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,06367852 0,10553913 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,06367852 0,10544431 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,06367852 0,10534966 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,06367852 0,10525517 ! cell part morphogenesis GO:0032990 75 70 1,000 0,06489621 0,10717179 ! wound healing GO:0042060 74 70 1,000 0,06489621 0,10707584 ! growth GO:0040007 70 70 1,000 0,06489621 0,10698006 ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,06653143 0,10957769 ! regulation of cell activation GO:0050865 71 71 1,000 0,06653143 0,10947985 ! positive regulation of hydrolase activity GO:0051345 72 72 1,000 0,06818052 0,1120934 ! translational initiation GO:0006413 12 12 0,000 0,06926728 0,11377861 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 0,000 0,06926728 0,11367729 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,06926728 0,11357615 ! initiation of viral infection GO:0019059 12 12 0,000 0,06926728 0,1134752 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 0,000 0,06926728 0,11337442 ! iron ion transport GO:0006826 13 12 0,000 0,06926728 0,11327382 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,06926728 0,1131734 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,06926728 0,11307316 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,06926728 0,1129731 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,06926728 0,11287321 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,06926728 0,1127735 ! collagen metabolic process GO:0032963 12 12 0,000 0,06926728 0,11267396 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,06926728 0,1125746 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,06926728 0,11247542 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,06926728 0,11237641 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,06926728 0,11227757 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,06926728 0,11217891 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,06926728 0,11208042 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,06926728 0,1119821 ! actomyosin structure organization GO:0031032 12 12 0,000 0,06926728 0,11188396 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,06926728 0,11178599 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,06926728 0,11168819 ! retinoid metabolic process GO:0001523 12 12 0,000 0,06926728 0,11159056 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,06926728 0,1114931 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,06926728 0,11139581 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,06926728 0,11129869 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,06926728 0,11120174 ! acute-phase response GO:0006953 12 12 0,000 0,06926728 0,11110496 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,06926728 0,11100835 ! vacuolar transport GO:0007034 12 12 0,000 0,06926728 0,1109119 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,06926728 0,11081562 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,06926728 0,11071951 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,06926728 0,11062357 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,06926728 0,11052779 GO:0051693|actin filament capping, ! osteoblast differentiation GO:0001649 12 12 0,000 0,06926728 0,11043218 ! male gonad development GO:0008584 12 12 0,000 0,06926728 0,11033673 ! regulation of insulin secretion GO:0050796 12 12 0,000 0,06926728 0,11024145 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,06926728 0,11014633 ! renal system process GO:0003014 12 12 0,000 0,06926728 0,11005138 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,06926728 0,10995659 ! regulation of steroid metabolic process GO:0019218 12 12 0,000 0,06926728 0,10986196 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 0,000 0,06926728 0,1097675 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,06926728 0,10967319 ! cell fate determination GO:0001709 12 12 0,000 0,06926728 0,10957905 ! regulation of chromosome organization GO:0033044 12 12 0,000 0,06926728 0,10948508 ! positive regulation of multicellular organism growth GO:0040018 12 12 0,000 0,06926728 0,10939126 ! G1 phase GO:0051318 13 12 0,000 0,06926728 0,1092976 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,06926728 0,1092041 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,06926728 0,10911077 ! synaptogenesis GO:0007416 12 12 0,000 0,06926728 0,10901759 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,06926728 0,10892457 ! hormone transport GO:0009914 12 12 0,000 0,06926728 0,10883171 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,06926728 0,10873901 ! heme biosynthetic process GO:0006783 12 12 0,000 0,06926728 0,10864647 ! spermatid differentiation GO:0048515 13 12 0,000 0,06926728 0,10855408 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,06926728 0,10846185 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,06926728 0,10836978 ! neural tube closure GO:0001843 13 12 0,000 0,06926728 0,10827786 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 0,000 0,06926728 0,1081861 ! negative regulation of translation GO:0017148 12 12 0,000 0,06926728 0,10809449 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,06926728 0,10800304 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,06926728 0,10791175 ! response to oxidative stress GO:0006979 76 75 1,000 0,07320881 0,11395594 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,07482349 0,11637105 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,07482349 0,11627293 ! phenol metabolic process GO:0018958 13 13 0,000 0,07482349 0,11617497 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! G2/M transition of mitotic cell cycle GO:0000086 13 13 0,000 0,07482349 0,11607718 ! gluconeogenesis GO:0006094 13 13 0,000 0,07482349 0,11597955 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,07482349 0,11588209 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,07482349 0,1157848 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,07482349 0,11568766 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,07482349 0,11559069 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 0,000 0,07482349 0,11549388 ! regeneration GO:0031099 13 13 0,000 0,07482349 0,11539723 ! keratinization GO:0031424 13 13 0,000 0,07482349 0,11530074 ! post-embryonic development GO:0009791 14 13 0,000 0,07482349 0,11520442 ! patterning of blood vessels GO:0001569 13 13 0,000 0,07482349 0,11510826 ! regulation of DNA recombination GO:0000018 13 13 0,000 0,07482349 0,11501225 ! regulation of innate immune response GO:0045088 13 13 0,000 0,07482349 0,11491641 ! mitochondrial membrane organization GO:0007006 13 13 0,000 0,07482349 0,11482073 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,07482349 0,1147252 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,07482349 0,11462983 ! response to corticosteroid stimulus GO:0031960 13 13 0,000 0,07482349 0,11453463 GO:0051384|response to glucocorticoid stimulus, ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,07482349 0,11443958 ! autophagy GO:0006914 13 13 0,000 0,07482349 0,11434469 ! actin filament bundle formation GO:0051017 13 13 0,000 0,07482349 0,11424995 ! ureteric bud development GO:0001657 13 13 0,000 0,07482349 0,11415537 ! cell aging GO:0007569 13 13 0,000 0,07482349 0,11406095 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,07482349 0,11396669 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,07482349 0,11387258 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! negative regulation of protein kinase cascade GO:0010741 13 13 0,000 0,07482349 0,11377862 ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,07482349 0,11368482 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,07482349 0,11359118 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,07482349 0,11349769 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,07482349 0,11340435 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,07482349 0,11331117 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,07482349 0,11321814 ! vasodilation GO:0042311 14 13 0,000 0,07482349 0,11312526 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,07482349 0,11303253 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,07482349 0,11293996 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,07482349 0,11284754 GO:0006664|glycolipid metabolic process, ! neural crest cell migration GO:0001755 14 13 0,000 0,07482349 0,11275527 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,07482349 0,11266315 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,07482349 0,11257118 ! immunoglobulin production GO:0002377 13 13 0,000 0,07482349 0,11247936 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,07482349 0,11238769 ! cell-cell junction organization GO:0045216 13 13 0,000 0,07482349 0,11229617 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 0,000 0,07482349 0,11220479 ! response to cytokine stimulus GO:0034097 13 13 0,000 0,07482349 0,11211357 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,07482349 0,11202249 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,07482349 0,11193157 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,07482349 0,11184079 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,07482349 0,11175015 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,07482349 0,11165967 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,07482349 0,11156933 ! camera-type eye morphogenesis GO:0048593 13 13 0,000 0,07482349 0,11147914 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,07482349 0,11138909 ! blastocyst development GO:0001824 13 13 0,000 0,07482349 0,11129919 ! telomere organization GO:0032200 13 13 0,000 0,07482349 0,11120943 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,07482349 0,11111982 ! regulation of amine transport GO:0051952 13 13 0,000 0,07482349 0,11103035 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,07482349 0,11094102 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,07491122 0,11098181 ! positive regulation of protein kinase cascade GO:0010740 79 78 1,000 0,07835426 0,11598948 ! neuron fate commitment GO:0048663 14 14 0,000 0,08034733 0,11884441 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,08034733 0,11874911 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,08034733 0,11865395 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,08034733 0,11855896 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,08034733 0,11846411 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,08034733 0,11836941 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,08034733 0,11827487 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,08034733 0,11818048 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,08034733 0,11808623 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,08034733 0,11799214 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,08034733 0,1178982 ! vesicle docking GO:0048278 14 14 0,000 0,08034733 0,1178044 ! superoxide metabolic process GO:0006801 15 14 0,000 0,08034733 0,11771076 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,08034733 0,11761726 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,08034733 0,11752392 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,08034733 0,11743072 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,08034733 0,11733767 ! hair cycle GO:0042633 14 14 0,000 0,08034733 0,11724476 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 0,000 0,08034733 0,11715201 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,08034733 0,1170594 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,08034733 0,11696693 GO:0033189|response to vitamin A, ! multicellular organismal response to stress GO:0033555 14 14 0,000 0,08034733 0,11687461 ! lysosome organization GO:0007040 14 14 0,000 0,08034733 0,11678244 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,08034733 0,11669041 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,08034733 0,11659853 ! peptide transport GO:0015833 14 14 0,000 0,08034733 0,11650679 ! primary neural tube formation GO:0014020 15 14 0,000 0,08034733 0,1164152 ! peptide cross-linking GO:0018149 14 14 0,000 0,08034733 0,11632375 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,08034733 0,11623245 ! response to organic cyclic substance GO:0014070 15 14 0,000 0,08034733 0,11614128 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,08034733 0,11605026 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,08034733 0,11595939 ! formation of primary germ layer GO:0001704 14 14 0,000 0,08034733 0,11586865 GO:0001707|mesoderm formation, ! DNA modification GO:0006304 14 14 0,000 0,08034733 0,11577806 ! collagen fibril organization GO:0030199 14 14 0,000 0,08034733 0,11568761 ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,08034733 0,1155973 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,08034733 0,11550713 ! positive regulation of inflammatory response GO:0050729 14 14 0,000 0,08034733 0,1154171 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,08034733 0,11532721 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,08034733 0,11523746 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,08034733 0,11514785 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,08034733 0,11505838 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,08034733 0,11496905 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,08034733 0,11487986 ! neuron projection development GO:0031175 85 80 1,000 0,08184693 0,11693324 ! MAPKKK cascade GO:0000165 82 81 1,000 0,08361136 0,11936154 ! lipid catabolic process GO:0016042 82 81 1,000 0,08361136 0,11926915 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,085839 0,1223521 ! positive regulation of fibroblast proliferation GO:0048146 15 15 0,000 0,085839 0,12225755 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,085839 0,12216314 ! positive regulation of ossification GO:0045778 15 15 0,000 0,085839 0,12206888 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,085839 0,12197477 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,085839 0,12188079 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,085839 0,12178697 ! response to vitamin GO:0033273 15 15 0,000 0,085839 0,12169329 ! striated muscle cell differentiation GO:0051146 16 15 0,000 0,085839 0,12159975 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,085839 0,12150635 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,085839 0,1214131 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,085839 0,12131999 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,085839 0,12122703 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,085839 0,1211342 ! heme metabolic process GO:0042168 15 15 0,000 0,085839 0,12104152 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,085839 0,12094898 ! response to starvation GO:0042594 15 15 0,000 0,085839 0,12085659 ! response to ionizing radiation GO:0010212 16 15 0,000 0,085839 0,12076433 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,085839 0,12067221 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,085839 0,12058024 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,085839 0,1204884 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,085839 0,12039671 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,085839 0,12030515 ! phospholipid transport GO:0015914 15 15 0,000 0,085839 0,12021373 ! leukocyte homeostasis GO:0001776 15 15 0,000 0,085839 0,12012245 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,085839 0,12003131 ! glutathione metabolic process GO:0006749 16 15 0,000 0,085839 0,11994031 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,085839 0,11984945 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of B cell activation GO:0050871 15 15 0,000 0,085839 0,11975872 ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,085839 0,11966813 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,085839 0,11957768 ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,085839 0,11948736 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,085839 0,11939719 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,09078525 0,12618191 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 0,000 0,09129866 0,12679987 ! alkaloid metabolic process GO:0009820 16 16 0,000 0,09129866 0,12670439 ! regulation of synaptic plasticity GO:0048167 16 16 0,000 0,09129866 0,12660905 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,09129866 0,12651386 ! learning GO:0007612 16 16 0,000 0,09129866 0,12641881 ! circadian rhythm GO:0007623 16 16 0,000 0,09129866 0,1263239 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,09129866 0,12622913 ! positive regulation of mitosis GO:0045840 16 16 0,000 0,09129866 0,12613451 GO:0051785|positive regulation of nuclear division, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,09129866 0,12604003 ! vacuole organization GO:0007033 16 16 0,000 0,09129866 0,12594568 ! cellular response to reactive oxygen species GO:0034614 16 16 0,000 0,09129866 0,12585148 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,09129866 0,12575742 ! vesicle targeting GO:0006903 17 16 0,000 0,09129866 0,12566351 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,09129866 0,12556973 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,09129866 0,12547609 ! iron ion homeostasis GO:0055072 16 16 0,000 0,09129866 0,12538259 ! positive regulation of cell development GO:0010720 16 16 0,000 0,09129866 0,12528923 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,09129866 0,12519601 ! lymphocyte proliferation GO:0046651 16 16 0,000 0,09129866 0,12510292 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,09129866 0,12500998 ! cell fate specification GO:0001708 16 16 0,000 0,09129866 0,12491717 ! pentose metabolic process GO:0019321 16 16 0,000 0,09129866 0,12482451 ! fatty acid transport GO:0015908 16 16 0,000 0,09129866 0,12473197 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,09129866 0,12463958 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,09129866 0,12454732 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,09129866 0,1244552 ! cofactor catabolic process GO:0051187 16 16 0,000 0,09129866 0,12436322 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,09129866 0,12427137 ! polyol metabolic process GO:0019751 16 16 0,000 0,09129866 0,12417966 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,09129866 0,12408808 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,09129866 0,12399663 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,09129866 0,12390533 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,09129866 0,12381415 GO:0001841|neural tube formation, ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,09129866 0,12372311 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,09129866 0,12363221 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,09129866 0,12354143 ! regulation of coagulation GO:0050818 17 16 0,000 0,09129866 0,12345079 ! hexose metabolic process GO:0019318 87 86 1,000 0,0926068 0,1251278 ! regulation of fibroblast proliferation GO:0048145 17 17 0,000 0,09672651 0,1305985 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,09672651 0,1305029 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,09672651 0,13040743 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,09672651 0,1303121 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,09672651 0,13021692 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,09672651 0,13012187 ! leukocyte adhesion GO:0007159 17 17 0,000 0,09672651 0,13002696 ! dicarboxylic acid metabolic process GO:0043648 18 17 0,000 0,09672651 0,12993219 ! sensory perception of smell GO:0007608 17 17 0,000 0,09672651 0,12983755 ! glucose transport GO:0015758 17 17 0,000 0,09672651 0,12974306 ! cell junction assembly GO:0034329 18 17 0,000 0,09672651 0,1296487 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,09672651 0,12955448 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,09672651 0,12946039 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,09672651 0,12936644 ! development of primary male sexual characteristics GO:0046546 17 17 0,000 0,09672651 0,12927263 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,09672651 0,12917896 ! neural crest cell development GO:0014032 19 17 0,000 0,09672651 0,12908542 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 18 17 0,000 0,09672651 0,12899201 ! negative regulation of cell development GO:0010721 18 17 0,000 0,09672651 0,12889874 GO:0050768|negative regulation of neurogenesis, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,09672651 0,12880561 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,09672651 0,12871261 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,09672651 0,12861974 ! regulation of osteoblast differentiation GO:0045667 17 17 0,000 0,09672651 0,12852701 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,09672651 0,12843441 ! pigmentation GO:0043473 17 17 0,000 0,09672651 0,12834194 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,09672651 0,12824961 ! adult locomotory behavior GO:0008344 17 17 0,000 0,09672651 0,12815741 ! embryonic organ development GO:0048568 17 17 0,000 0,09672651 0,12806534 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,09672651 0,12797341 ! liver development GO:0001889 17 17 0,000 0,09672651 0,12788161 ! gene silencing GO:0016458 17 17 0,000 0,09672651 0,12778993 ! chemotaxis GO:0006935 90 89 1,000 0,09813579 0,12955893 GO:0042330|taxis, ! brain development GO:0007420 91 90 1,000 0,09999963 0,13192506 ! negative regulation of cell cycle GO:0045786 92 91 1,000 0,10187358 0,13430115 ! DNA replication GO:0006260 91 91 1,000 0,10187358 0,13420515 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,10212272 0,13443727 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,10212272 0,13434131 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,10212272 0,13424549 ! membrane docking GO:0022406 18 18 0,000 0,10212272 0,13414981 ! mononuclear cell proliferation GO:0032943 18 18 0,000 0,10212272 0,13405426 GO:0070661|leukocyte proliferation, ! response to calcium ion GO:0051592 18 18 0,000 0,10212272 0,13395885 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,10212272 0,13386357 ! hexose transport GO:0008645 18 18 0,000 0,10212272 0,13376843 GO:0015749|monosaccharide transport, ! cholesterol homeostasis GO:0042632 18 18 0,000 0,10212272 0,13367342 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,10212272 0,13357855 ! striated muscle contraction GO:0006941 18 18 0,000 0,10212272 0,13348382 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,10212272 0,13338921 GO:0006639|acylglycerol metabolic process, ! ceramide metabolic process GO:0006672 18 18 0,000 0,10212272 0,13329475 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,10212272 0,13320041 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! hexose biosynthetic process GO:0019319 18 18 0,000 0,10212272 0,13310621 ! negative regulation of MAP kinase activity GO:0043407 18 18 0,000 0,10212272 0,13301214 ! B cell differentiation GO:0030183 18 18 0,000 0,10212272 0,13291821 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,10212272 0,1328244 ! BMP signaling pathway GO:0030509 18 18 0,000 0,10212272 0,13273073 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,10212272 0,1326372 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,10212272 0,13254379 ! visual perception GO:0007601 93 92 1,000 0,10375747 0,13457074 GO:0050953|sensory perception of light stimulus, ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,10375747 0,1344761 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,10375747 0,1343816 ! DNA damage checkpoint GO:0000077 19 19 0,000 0,10748748 0,13911477 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,10748748 0,13901714 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,10748748 0,13891966 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,10748748 0,1388223 ! glial cell differentiation GO:0010001 19 19 0,000 0,10748748 0,13872509 ! regulation of pH GO:0006885 19 19 0,000 0,10748748 0,13862801 ! regulation of JAK-STAT cascade GO:0046425 19 19 0,000 0,10748748 0,13853107 ! feeding behavior GO:0007631 19 19 0,000 0,10748748 0,13843426 ! peroxisome organization GO:0007031 19 19 0,000 0,10748748 0,13833759 ! positive regulation of T cell proliferation GO:0042102 19 19 0,000 0,10748748 0,13824105 ! regulation of striated muscle tissue development GO:0016202 20 19 0,000 0,10748748 0,13814465 ! multicellular organismal metabolic process GO:0044236 19 19 0,000 0,10748748 0,13804838 ! metanephros development GO:0001656 19 19 0,000 0,10748748 0,13795225 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,10748748 0,13785625 ! cellular response to oxidative stress GO:0034599 19 19 0,000 0,10748748 0,13776038 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,10748748 0,13766465 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,10748748 0,13756905 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,10748748 0,13747358 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,10748748 0,13737824 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,10748748 0,13728304 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,10748748 0,13718797 ! eye morphogenesis GO:0048592 19 19 0,000 0,10748748 0,13709303 ! placenta development GO:0001890 19 19 0,000 0,10748748 0,13699822 ! vesicle localization GO:0051648 20 19 0,000 0,10748748 0,13690354 ! pattern specification process GO:0007389 96 94 1,000 0,10755435 0,13689411 ! regulation of cell growth GO:0001558 97 96 1,000 0,11138888 0,14167681 ! regulation of muscle development GO:0048634 21 20 0,000 0,11282096 0,14339933 ! organic ether metabolic process GO:0018904 20 20 0,000 0,11282096 0,14330051 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,11282096 0,14320181 ! neural tube development GO:0021915 21 20 0,000 0,11282096 0,14310326 ! phagocytosis GO:0006909 21 20 0,000 0,11282096 0,14300484 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,11282096 0,14290655 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,11282096 0,1428084 ! protein targeting to membrane GO:0006612 22 20 0,000 0,11282096 0,14271039 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,11282096 0,14261251 ! chromatin remodeling GO:0006338 20 20 0,000 0,11282096 0,14251476 ! lipid oxidation GO:0034440 20 20 0,000 0,11282096 0,14241715 GO:0019395|fatty acid oxidation, ! female gamete generation GO:0007292 20 20 0,000 0,11282096 0,14231967 ! negative regulation of neuron apoptosis GO:0043524 21 20 0,000 0,11282096 0,14222232 ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,11282096 0,14212511 ! RNA modification GO:0009451 20 20 0,000 0,11282096 0,14202803 ! single fertilization GO:0007338 21 20 0,000 0,11282096 0,14193108 ! regulation of B cell activation GO:0050864 20 20 0,000 0,11282096 0,14183427 ! blood circulation GO:0008015 99 98 1,000 0,11525966 0,14480133 GO:0003013|circulatory system process, ! mitotic sister chromatid segregation GO:0000070 21 21 0,000 0,11812334 0,14829791 ! mRNA catabolic process GO:0006402 21 21 0,000 0,11812334 0,14819695 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 0,000 0,11812334 0,14809614 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! protein amino acid lipidation GO:0006497 21 21 0,000 0,11812334 0,14799546 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,11812334 0,14789492 ! Notch signaling pathway GO:0007219 22 21 0,000 0,11812334 0,14779452 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,11812334 0,14769425 ! ear morphogenesis GO:0042471 21 21 0,000 0,11812334 0,14759412 ! organic anion transport GO:0015711 21 21 0,000 0,11812334 0,14749412 ! cholesterol transport GO:0030301 21 21 0,000 0,11812334 0,14739426 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,11812334 0,14729454 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,11812334 0,14719495 GO:0032313|regulation of Rab GTPase activity, ! DNA integrity checkpoint GO:0031570 21 21 0,000 0,11812334 0,14709549 ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,11812334 0,14699617 ! regulation of multicellular organism growth GO:0040014 21 21 0,000 0,11812334 0,14689698 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 0,000 0,11812334 0,14679793 ! regulation of proteolysis GO:0030162 21 21 0,000 0,11812334 0,14669901 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,11812334 0,14660022 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,11812334 0,14650156 ! hemopoiesis GO:0030097 104 100 1,000 0,11916536 0,14769452 ! RNA export from nucleus GO:0006405 22 22 0,000 0,1233948 0,15283375 ! sister chromatid segregation GO:0000819 22 22 0,000 0,1233948 0,15273111 ! cellular amide metabolic process GO:0043603 22 22 0,000 0,1233948 0,15262861 ! regulation of ion transport GO:0043269 22 22 0,000 0,1233948 0,15252624 ! odontogenesis GO:0042476 22 22 0,000 0,1233948 0,15242401 ! cell junction organization GO:0034330 23 22 0,000 0,1233948 0,15232192 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 0,000 0,1233948 0,15221996 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! hormone-mediated signaling GO:0009755 22 22 0,000 0,1233948 0,15211814 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,1233948 0,15201646 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,1233948 0,15191491 ! cell chemotaxis GO:0060326 23 22 0,000 0,1233948 0,1518135 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,1233948 0,15171222 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,1233948 0,15161108 ! male sex differentiation GO:0046661 22 22 0,000 0,1233948 0,15151008 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,1233948 0,1514092 ! biopolymer methylation GO:0043414 22 22 0,000 0,1233948 0,15130847 GO:0032259|methylation, ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,1233948 0,15120786 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,1233948 0,15110739 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,1233948 0,15100706 ! positive regulation of lymphocyte differentiation GO:0045621 22 22 0,000 0,1233948 0,15090685 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,1233948 0,15080678 ! aerobic respiration GO:0009060 22 22 0,000 0,1233948 0,15070684 ! cytokine production GO:0001816 22 22 0,000 0,1233948 0,15060704 ! cytokinesis GO:0000910 23 22 0,000 0,1233948 0,15050736 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,1233948 0,15040782 ! response to hydrogen peroxide GO:0042542 24 23 0,000 0,12863552 0,15669217 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,12863552 0,15658868 ! viral infectious cycle GO:0019058 23 23 0,000 0,12863552 0,15648532 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,12863552 0,1563821 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,12863552 0,15627901 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,12863552 0,15617606 ! mitotic cell cycle checkpoint GO:0007093 24 23 0,000 0,12863552 0,15607325 ! induction of apoptosis by extracellular signals GO:0008624 23 23 0,000 0,12863552 0,15597057 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,12863552 0,15586802 ! endocrine system development GO:0035270 23 23 0,000 0,12863552 0,15576561 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,12863552 0,15566334 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,12863552 0,15556119 ! lipid homeostasis GO:0055088 23 23 0,000 0,12863552 0,15545919 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,12863552 0,15535731 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,12863552 0,15525557 ! mitochondrial transport GO:0006839 24 24 0,000 0,13384566 0,16143819 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,13384566 0,1613326 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,13384566 0,16122716 ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,13384566 0,16112185 ! T cell differentiation GO:0030217 24 24 0,000 0,13384566 0,16101668 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,13384566 0,16091164 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,13384566 0,16080675 ! fertilization GO:0009566 25 24 0,000 0,13384566 0,16070199 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,13384566 0,16059736 ! epithelial tube morphogenesis GO:0060562 25 24 0,000 0,13384566 0,16049288 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,1390254 0,16659546 ! negative regulation of secretion GO:0051048 26 25 0,000 0,1390254 0,16648721 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,1390254 0,1663791 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,1390254 0,16627114 ! cellular component disassembly GO:0022411 26 25 0,000 0,1390254 0,16616331 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,1390254 0,16605562 ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,1390254 0,16594807 ! excretion GO:0007588 25 25 0,000 0,1390254 0,16584066 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,1390254 0,16573339 ! gastrulation GO:0007369 25 25 0,000 0,1390254 0,16562626 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,1390254 0,16551926 ! regulation of endocytosis GO:0030100 25 25 0,000 0,1390254 0,16541241 ! JAK-STAT cascade GO:0007259 26 25 0,000 0,1390254 0,16530569 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,1390254 0,16519911 ! positive regulation of defense response GO:0031349 26 26 0,000 0,14417492 0,17120772 ! glycolysis GO:0006096 26 26 0,000 0,14417492 0,17109748 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,14417492 0,17098738 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,14417492 0,17087742 ! negative regulation of cell migration GO:0030336 26 26 0,000 0,14417492 0,1707676 ! induction of apoptosis by intracellular signals GO:0008629 26 26 0,000 0,14417492 0,17065792 ! cellular defense response GO:0006968 26 26 0,000 0,14417492 0,17054839 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 0,000 0,14417492 0,17043899 ! regulation of protein secretion GO:0050708 26 26 0,000 0,14417492 0,17032973 ! germ cell development GO:0007281 27 26 0,000 0,14417492 0,17022062 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,14417492 0,17011164 GO:0035150|regulation of tube size, ! pigment metabolic process GO:0042440 26 26 0,000 0,14417492 0,17000281 ! chloride transport GO:0006821 27 27 0,000 0,14929439 0,17592683 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,14929439 0,17581442 ! learning or memory GO:0007611 28 27 0,000 0,14929439 0,17570215 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,14929439 0,17559002 ! peptide metabolic process GO:0006518 29 27 0,000 0,14929439 0,17547804 ! activation of caspase activity GO:0006919 27 27 0,000 0,14929439 0,1753662 ! inner ear development GO:0048839 27 27 0,000 0,14929439 0,1752545 ! defense response to bacterium GO:0042742 27 27 0,000 0,14929439 0,17514294 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,14929439 0,17503153 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,14929439 0,17492026 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,15438398 0,18076853 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,15438398 0,18065376 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,15438398 0,18053913 ! carbohydrate transport GO:0008643 28 28 0,000 0,15438398 0,18042465 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,15438398 0,18031031 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,15438398 0,18019612 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,15438398 0,18008207 ! keratinocyte differentiation GO:0030216 28 28 0,000 0,15438398 0,17996817 ! developmental growth GO:0048589 28 28 0,000 0,15438398 0,17985441 ! cartilage development GO:0051216 29 28 0,000 0,15438398 0,17974079 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,15944385 0,18551453 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,15944385 0,18539749 ! leukocyte migration GO:0050900 30 29 0,000 0,15944385 0,18528059 ! antigen processing and presentation GO:0019882 29 29 0,000 0,15944385 0,18516384 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,15944385 0,18504724 ! tRNA processing GO:0008033 29 29 0,000 0,15944385 0,18493079 ! regulation of gene expression, epigenetic GO:0040029 29 29 0,000 0,15944385 0,18481448 ! adult behavior GO:0030534 30 29 0,000 0,15944385 0,18469831 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,15944385 0,1845823 ! transition metal ion transport GO:0000041 31 30 0,000 0,16447418 0,1902862 ! RNA catabolic process GO:0006401 30 30 0,000 0,16447418 0,19016683 ! response to reactive oxygen species GO:0000302 31 30 0,000 0,16447418 0,1900476 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,16447418 0,18992852 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,16447418 0,18980959 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,16447418 0,18969081 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,16447418 0,18957218 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,16447418 0,1894537 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 0,000 0,16447418 0,18933536 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,16447418 0,18921718 ! regulation of ossification GO:0030278 30 30 0,000 0,16447418 0,18909914 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,16447418 0,18898125 GO:0019724|B cell mediated immunity, ! regulation of inflammatory response GO:0050727 30 30 0,000 0,16447418 0,1888635 ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,16447418 0,1887459 ! vesicle organization GO:0016050 30 30 0,000 0,16447418 0,18862845 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,16447418 0,18851114 ! membrane fusion GO:0006944 31 31 0,000 0,16947514 0,19412224 ! B cell activation GO:0042113 31 31 0,000 0,16947514 0,19400167 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,16947514 0,19388124 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,16947514 0,19376097 ! ion transmembrane transport GO:0034220 31 31 0,000 0,16947514 0,19364085 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! aging GO:0007568 32 31 0,000 0,16947514 0,19352087 ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,16947514 0,19340104 ! digestion GO:0007586 31 31 0,000 0,16947514 0,19328136 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,16947514 0,19316183 ! regulation of heart contraction GO:0008016 31 31 0,000 0,16947514 0,19304245 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,16947514 0,19292321 ! camera-type eye development GO:0043010 31 31 0,000 0,16947514 0,19280413 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,16947514 0,19268518 ! epidermal cell differentiation GO:0009913 31 31 0,000 0,16947514 0,19256639 ! regulation of myeloid cell differentiation GO:0045637 32 31 0,000 0,16947514 0,19244774 ! negative regulation of cell motion GO:0051271 31 31 0,000 0,16947514 0,19232924 ! negative regulation of cell growth GO:0030308 32 32 0,000 0,17444689 0,19784961 ! cell redox homeostasis GO:0045454 32 32 0,000 0,17444689 0,19772793 ! glucose catabolic process GO:0006007 32 32 0,000 0,17444689 0,1976064 ! lipid modification GO:0030258 32 32 0,000 0,17444689 0,19748502 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,17444689 0,19736379 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,17444689 0,19724271 ! cell maturation GO:0048469 32 32 0,000 0,17444689 0,19712178 ! nuclear export GO:0051168 32 32 0,000 0,17444689 0,19700099 ! kidney development GO:0001822 32 32 0,000 0,17444689 0,19688036 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,17444689 0,19675987 ! negative regulation of cell size GO:0045792 33 33 0,000 0,1793896 0,20221103 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,1793896 0,20208743 ! amino acid transport GO:0006865 33 33 0,000 0,1793896 0,20196398 ! activation of protein kinase activity GO:0032147 35 33 0,000 0,1793896 0,20184068 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,1793896 0,20171753 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,1793896 0,20159453 ! regulation of neuron differentiation GO:0045664 34 33 0,000 0,1793896 0,20147168 ! regulation of neuron apoptosis GO:0043523 34 33 0,000 0,1793896 0,20134899 ! regulation of synaptic transmission GO:0050804 33 33 0,000 0,1793896 0,20122644 ! regulation of actin filament length GO:0030832 34 34 0,000 0,18430344 0,20661267 ! response to metal ion GO:0010038 34 34 0,000 0,18430344 0,20648707 ! ear development GO:0043583 34 34 0,000 0,18430344 0,20636162 ! muscle cell differentiation GO:0042692 35 34 0,000 0,18430344 0,20623633 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,18430344 0,20611118 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,18430344 0,20598619 ! secondary metabolic process GO:0019748 34 34 0,000 0,18430344 0,20586135 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,18430344 0,20573666 ! acute inflammatory response GO:0002526 35 35 0,000 0,18918856 0,21106206 ! regulation of cellular component size GO:0032535 35 35 0,000 0,18918856 0,21093437 ! regulation of cytokine biosynthetic process GO:0042035 35 35 0,000 0,18918856 0,21080684 ! mesoderm development GO:0007498 35 35 0,000 0,18918856 0,21067947 ! inorganic anion transport GO:0015698 35 35 0,000 0,18918856 0,21055224 ! regulation of immune effector process GO:0002697 35 35 0,000 0,18918856 0,21042518 ! hydrogen transport GO:0006818 36 36 0,000 0,19404514 0,21569673 GO:0015992|proton transport, ! response to inorganic substance GO:0010035 36 36 0,000 0,19404514 0,21556672 ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,19404514 0,21543686 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 0,000 0,19404514 0,21530716 ! regulation of mitosis GO:0007088 37 36 0,000 0,19404514 0,21517761 GO:0051783|regulation of nuclear division, ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,19404514 0,21504822 GO:0035113|embryonic appendage morphogenesis, ! female pregnancy GO:0007565 37 36 0,000 0,19404514 0,21491898 ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,19404514 0,2147899 ! positive regulation of organelle organization GO:0010638 36 36 0,000 0,19404514 0,21466098 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,19404514 0,21453221 ! integrin-mediated signaling pathway GO:0007229 36 36 0,000 0,19404514 0,21440359 ! regulation of transmission of nerve impulse GO:0051969 36 36 0,000 0,19404514 0,21427513 ! activation of immune response GO:0002253 36 36 0,000 0,19404514 0,21414682 ! coagulation GO:0050817 39 36 0,000 0,19404514 0,21401866 GO:0007596|blood coagulation, ! response to drug GO:0042493 37 37 0,000 0,19887333 0,21921265 ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,19887333 0,21908162 ! eye development GO:0001654 37 37 0,000 0,19887333 0,21895074 ! negative regulation of growth GO:0045926 37 37 0,000 0,19887333 0,21882003 ! DNA damage response, signal transduction GO:0042770 37 37 0,000 0,19887333 0,21868947 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,19887333 0,21855906 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,19887333 0,21842881 ! regulation of Rho protein signal transduction GO:0035023 37 37 0,000 0,19887333 0,21829872 ! positive regulation of secretion GO:0051047 39 38 0,000 0,2036733 0,22343446 ! neurotransmitter transport GO:0006836 40 38 0,000 0,2036733 0,22330154 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,2036733 0,22316878 ! exocytosis GO:0006887 40 38 0,000 0,2036733 0,22303618 ! cell-matrix adhesion GO:0007160 39 38 0,000 0,2036733 0,22290373 ! hexose catabolic process GO:0019320 38 38 0,000 0,2036733 0,22277145 ! RNA elongation GO:0006354 38 38 0,000 0,2036733 0,22263932 ! regulation of neurological system process GO:0031644 38 38 0,000 0,2036733 0,22250734 ! hemostasis GO:0007599 42 39 0,000 0,20844521 0,22758561 ! positive regulation of protein modification process GO:0031401 39 39 0,000 0,20844521 0,22745087 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,20844521 0,22731628 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,20844521 0,22718185 ! cytokine-mediated signaling pathway GO:0019221 39 39 0,000 0,20844521 0,22704759 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,20844521 0,22691348 ! regulation of MAPKKK cascade GO:0043408 41 39 0,000 0,20844521 0,22677953 ! positive regulation of T cell activation GO:0050870 39 39 0,000 0,20844521 0,22664573 ! developmental maturation GO:0021700 39 39 0,000 0,20844521 0,2265121 ! lymphocyte differentiation GO:0030098 39 39 0,000 0,20844521 0,22637862 ! limb development GO:0060173 39 39 0,000 0,20844521 0,2262453 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! DNA catabolic process GO:0006308 41 40 0,000 0,21318921 0,23125822 ! cell cycle checkpoint GO:0000075 42 41 0,000 0,21790548 0,23623517 ! amine catabolic process GO:0009310 42 41 0,000 0,21790548 0,23609629 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 0,000 0,21790548 0,23595758 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,21790548 0,23581902 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,21790548 0,23568063 ! regulation of Ras GTPase activity GO:0032318 41 41 0,000 0,21790548 0,2355424 ! monosaccharide catabolic process GO:0046365 41 41 0,000 0,21790548 0,23540433 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,22259416 0,24032866 ! cytosolic calcium ion homeostasis GO:0051480 42 42 0,000 0,22259416 0,24018796 ! cell-substrate adhesion GO:0031589 43 42 0,000 0,22259416 0,24004741 ! negative regulation of ligase activity GO:0051352 43 42 0,000 0,22259416 0,23990703 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! one-carbon metabolic process GO:0006730 42 42 0,000 0,22259416 0,23976682 ! mitochondrion organization GO:0007005 44 43 0,000 0,22725541 0,24464469 ! alcohol catabolic process GO:0046164 43 43 0,000 0,22725541 0,24450188 ! homeostasis of number of cells GO:0048872 44 43 0,000 0,22725541 0,24435923 ! humoral immune response GO:0006959 44 44 0,000 0,23188939 0,24919658 ! mRNA transport GO:0051028 44 44 0,000 0,23188939 0,24905137 ! protein import into nucleus GO:0006606 44 44 0,000 0,23188939 0,24890631 ! negative regulation of organelle organization GO:0010639 45 44 0,000 0,23188939 0,24876143 ! vitamin metabolic process GO:0006766 44 44 0,000 0,23188939 0,24861672 ! positive regulation of lymphocyte activation GO:0051251 44 44 0,000 0,23188939 0,24847218 ! amine biosynthetic process GO:0009309 46 45 0,000 0,23649625 0,25326124 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,23649625 0,25311417 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,23649625 0,25296726 ! nuclear import GO:0051170 45 45 0,000 0,23649625 0,25282053 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,24107616 0,25756717 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,24107616 0,25741794 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,24562926 0,26212781 ! regulation of blood pressure GO:0008217 48 47 0,000 0,24562926 0,26197611 ! amine transport GO:0015837 47 47 0,000 0,24562926 0,26182459 ! calcium ion transport GO:0006816 48 48 0,000 0,2501557 0,26649535 ! regulation of cell cycle process GO:0010564 50 48 0,000 0,2501557 0,2663414 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,2501557 0,26618762 ! protein localization in nucleus GO:0034504 48 48 0,000 0,2501557 0,26603402 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,25465565 0,27066341 ! divalent metal ion transport GO:0070838 49 49 0,000 0,25465565 0,27050741 ! response to nutrient GO:0007584 49 49 0,000 0,25465565 0,27035159 ! response to bacterium GO:0009617 50 49 0,000 0,25465565 0,27019595 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,25465565 0,27004048 ! positive regulation of cell activation GO:0050867 49 49 0,000 0,25465565 0,2698852 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 0,000 0,25912924 0,2744685 ! RNA transport GO:0050658 50 50 0,000 0,25912924 0,27431085 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! T cell activation GO:0042110 51 50 0,000 0,25912924 0,27415338 ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,25912924 0,27399609 ! regulation of neurogenesis GO:0050767 51 50 0,000 0,25912924 0,27383899 ! transcription initiation GO:0006352 50 50 0,000 0,25912924 0,27368206 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,26357664 0,27821978 ! positive regulation of immune response GO:0050778 51 51 0,000 0,26357664 0,27806053 ! rRNA metabolic process GO:0016072 51 51 0,000 0,26357664 0,27790145 GO:0006364|rRNA processing, ! ATP biosynthetic process GO:0006754 51 51 0,000 0,26357664 0,27774256 ! RNA localization GO:0006403 52 52 0,000 0,26799798 0,28224016 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,26799798 0,28207897 ! cell fate commitment GO:0045165 52 52 0,000 0,26799798 0,28191797 ! regulation of GTPase activity GO:0043087 53 52 0,000 0,26799798 0,28175715 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,26799798 0,28159651 ! sodium ion transport GO:0006814 53 53 0,000 0,27239342 0,2860519 ! tRNA metabolic process GO:0006399 53 53 0,000 0,27239342 0,285889 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,27239342 0,28572628 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,27239342 0,28556375 ! carbohydrate catabolic process GO:0016052 53 53 0,000 0,27239342 0,28540141 ! protein amino acid dephosphorylation GO:0006470 55 54 0,000 0,27676311 0,28981501 ! response to virus GO:0009615 54 54 0,000 0,27676311 0,28965043 ! hormone metabolic process GO:0042445 55 54 0,000 0,27676311 0,28948605 ! sulfur metabolic process GO:0006790 55 54 0,000 0,27676311 0,28932185 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,28110719 0,29369646 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! in utero embryonic development GO:0001701 55 55 0,000 0,28110719 0,29353006 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,28542582 0,29787077 ! regulation of nervous system development GO:0051960 57 56 0,000 0,28542582 0,2977022 ! ATP metabolic process GO:0046034 57 57 0,000 0,28971913 0,30200925 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,28971913 0,30183853 ! innate immune response GO:0045087 58 58 0,000 0,29398727 0,30611217 ! dephosphorylation GO:0016311 60 59 0,000 0,29823038 0,31035494 ! carboxylic acid transport GO:0046942 59 59 0,000 0,29823038 0,31017979 GO:0015849|organic acid transport, ! regulation of cell development GO:0060284 60 59 0,000 0,29823038 0,31000485 ! sterol metabolic process GO:0016125 59 59 0,000 0,29823038 0,3098301 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,29823038 0,30965554 ! protein localization in organelle GO:0033365 59 59 0,000 0,29823038 0,30948119 ! immune effector process GO:0002252 59 59 0,000 0,29823038 0,30930703 ! potassium ion transport GO:0006813 60 60 0,000 0,30244861 0,31350551 ! cellular respiration GO:0045333 62 61 0,000 0,3066421 0,31767363 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,3066421 0,31749517 GO:0016054|organic acid catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 0,000 0,3066421 0,3173169 ! lipid transport GO:0006869 62 62 0,000 0,31081099 0,32145043 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,31081099 0,32127014 ! morphogenesis of an epithelium GO:0002009 63 62 0,000 0,31081099 0,32109006 GO:0060429|epithelium development, ! protein import GO:0017038 62 62 0,000 0,31081099 0,32091017 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,31081099 0,32073049 ! regulation of secretion GO:0051046 65 63 0,000 0,31495543 0,32482532 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,31495543 0,32464365 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,31495543 0,32446219 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,31907554 0,32852303 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,31907554 0,3283396 ! anion transport GO:0006820 65 65 0,000 0,32317148 0,33236888 ! regulation of hormone levels GO:0010817 66 65 0,000 0,32317148 0,33218351 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,32724338 0,33618146 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,32724338 0,33599417 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,33129137 0,33996102 ! muscle contraction GO:0006936 67 67 0,000 0,33129137 0,33977184 ! negative regulation of cell differentiation GO:0045596 68 67 0,000 0,33129137 0,33958287 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,33531559 0,34351675 ! sensory perception of sound GO:0007605 71 69 0,000 0,33931619 0,34742208 GO:0050954|sensory perception of mechanical stimulus, ! response to nutrient levels GO:0031667 69 69 0,000 0,33931619 0,34722917 ! regulation of mitotic cell cycle GO:0007346 72 69 0,000 0,33931619 0,34703648 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,34329329 0,35090934 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,34724703 0,35475404 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,34724703 0,3545575 ! calcium ion homeostasis GO:0055074 71 71 0,000 0,34724703 0,35436117 GO:0006874|cellular calcium ion homeostasis, ! ribosome biogenesis GO:0042254 71 71 0,000 0,34724703 0,35416507 ! secretion by cell GO:0032940 75 72 0,000 0,35117755 0,35797578 ! muscle system process GO:0003012 72 72 0,000 0,35117755 0,3577779 ! sensory organ development GO:0007423 72 72 0,000 0,35117755 0,35758023 ! response to extracellular stimulus GO:0009991 72 72 0,000 0,35117755 0,35738278 ! regulation of cytokine production GO:0001817 72 72 0,000 0,35117755 0,35718555 ! electron transport chain GO:0022900 75 74 0,000 0,35896943 0,36490935 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,35896943 0,36470819 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,36283106 0,36842845 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,36283106 0,36822557 ! positive regulation of multicellular organismal process GO:0051240 76 76 0,000 0,36666999 0,37191678 ! cellular metal ion homeostasis GO:0006875 77 77 0,000 0,37048635 0,37558105 ! metal ion homeostasis GO:0055065 78 78 0,000 0,37428027 0,37921855 ! regulation of immune response GO:0050776 78 78 0,000 0,37428027 0,37901019 ! nuclear transport GO:0051169 79 79 0,000 0,37805189 0,38261924 GO:0006913|nucleocytoplasmic transport, ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,38180132 0,38620188 ! lymphocyte activation GO:0046649 82 81 0,000 0,38552869 0,3897583 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,39291778 0,39701067 ! ncRNA processing GO:0034470 83 83 0,000 0,39291778 0,39679313 ! cellular amino acid derivative metabolic process GO:0006575 87 84 0,000 0,39657974 0,40027189 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,40022015 0,40372509 ! positive regulation of cell differentiation GO:0045597 87 85 0,000 0,40022015 0,40350424 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,40383913 0,4069303 GO:0006644|phospholipid metabolic process, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,4110133 0,41393306 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 0,000 0,41456872 0,41728572 ! regulation of Ras protein signal transduction GO:0046578 90 90 0,000 0,41810321 0,42061365 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 0,000 0,42161687 0,42391702 ! fatty acid metabolic process GO:0006631 93 92 0,000 0,42510983 0,42719597 ! tissue morphogenesis GO:0048729 94 93 0,000 0,42858221 0,43045069 ! regulation of response to stress GO:0080134 97 94 0,000 0,43203412 0,43368131 ! epidermis development GO:0008544 94 94 0,000 0,43203412 0,43344523 ! cofactor metabolic process GO:0051186 95 94 0,000 0,43203412 0,4332094 ! endocytosis GO:0006897 99 98 0,000 0,44563946 0,44660877 GO:0010324|membrane invagination, ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,44563946 0,44636605 ! regulation of system process GO:0044057 98 98 0,000 0,44563946 0,44612359 ! ectoderm development GO:0007398 99 99 0,000 0,4489908 0,44923455 ! response to other organism GO:0051707 101 100 0,000 0,45232237 0,45232237