pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6410-VanDeVijver-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/vantveer-oligo_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! T cell homeostasis GO:0043029 8 8 3,000 1,431E-07 2,637E-04 ! lymphocyte homeostasis GO:0002260 10 10 3,000 4,248E-07 3,915E-04 ! positive regulation of multicellular organism growth GO:0040018 12 12 3,000 9,911E-07 6,089E-04 ! interphase of mitotic cell cycle GO:0051329 52 51 5,000 1,187E-06 5,47E-04 GO:0051325|interphase, ! response to light stimulus GO:0009416 53 52 5,000 1,335E-06 4,921E-04 ! regulation of cell-substrate adhesion GO:0010810 14 13 3,000 1,424E-06 4,375E-04 GO:0001952|regulation of cell-matrix adhesion, ! response to hypoxia GO:0001666 53 53 5,000 1,497E-06 3,943E-04 ! response to oxygen levels GO:0070482 55 54 5,000 1,676E-06 3,861E-04 ! regulation of cell adhesion GO:0030155 56 55 5,000 1,871E-06 3,832E-04 ! leukocyte homeostasis GO:0001776 15 15 3,000 2,691E-06 4,96E-04 ! peptidyl-amino acid modification GO:0018193 61 59 5,000 2,848E-06 4,771E-04 ! 2-oxoglutarate metabolic process GO:0006103 5 5 2,000 3,157E-06 4,848E-04 ! regulation of MAP kinase activity GO:0043405 67 66 5,000 5,535E-06 7,847E-04 ! regulation of homeostatic process GO:0032844 38 38 4,000 5,64E-06 7,424E-04 ! Ras protein signal transduction GO:0007265 69 67 5,000 6,048E-06 7,431E-04 ! regulation of activated T cell proliferation GO:0046006 6 6 2,000 6,283E-06 7,237E-04 ! succinate metabolic process GO:0006105 7 6 2,000 6,283E-06 6,811E-04 ! focal adhesion formation GO:0048041 7 6 2,000 6,283E-06 6,433E-04 ! negative regulation of T cell proliferation GO:0042130 6 6 2,000 6,283E-06 6,094E-04 GO:0070667|negative regulation of mast cell proliferation, ! peptidyl-serine phosphorylation GO:0018105 6 6 2,000 6,283E-06 5,789E-04 ! phosphoinositide 3-kinase cascade GO:0014065 6 6 2,000 6,283E-06 5,514E-04 ! response to radiation GO:0009314 70 68 5,000 6,598E-06 5,528E-04 ! regulation of mitotic cell cycle GO:0007346 72 69 5,000 7,189E-06 5,76E-04 ! regulation of cell migration GO:0030334 71 71 5,000 8,499E-06 6,526E-04 ! oxaloacetate metabolic process GO:0006107 7 7 2,000 1,094E-05 8,065E-04 ! visual behavior GO:0007632 7 7 2,000 1,094E-05 7,755E-04 GO:0008542|visual learning, ! negative regulation of lymphocyte proliferation GO:0050672 7 7 2,000 1,094E-05 7,468E-04 GO:0032945|negative regulation of mononuclear cell proliferation, GO:0070664|negative regulation of leukocyte proliferation, ! negative regulation of T cell activation GO:0050868 7 7 2,000 1,094E-05 7,201E-04 ! G1/S transition of mitotic cell cycle GO:0000082 21 21 3,000 1,144E-05 7,272E-04 ! regulation of multicellular organism growth GO:0040014 21 21 3,000 1,144E-05 7,03E-04 ! cell morphogenesis involved in differentiation GO:0000904 82 77 5,000 1,363E-05 8,105E-04 ! regulation of membrane potential GO:0042391 46 46 4,000 1,477E-05 8,507E-04 ! regulation of locomotion GO:0040012 79 79 5,000 1,582E-05 8,833E-04 ! regulation of cell motion GO:0051270 79 79 5,000 1,582E-05 8,573E-04 ! positive regulation of growth GO:0045927 23 23 3,000 1,676E-05 8,824E-04 ! phosphagen metabolic process GO:0006599 8 8 2,000 1,742E-05 8,918E-04 GO:0006600|creatine metabolic process, ! peptidyl-serine modification GO:0018209 8 8 2,000 1,742E-05 8,677E-04 ! branched chain family amino acid metabolic process GO:0009081 8 8 2,000 1,742E-05 8,448E-04 ! release of cytochrome c from mitochondria GO:0001836 9 8 2,000 1,742E-05 8,232E-04 ! gland development GO:0048732 51 49 4,000 2,023E-05 9,321E-04 ! positive regulation of MAP kinase activity GO:0043406 50 49 4,000 2,023E-05 9,093E-04 ! regulation of intracellular protein transport GO:0033157 25 25 3,000 2,37E-05 1,04E-03 ! regulation of T cell proliferation GO:0042129 25 25 3,000 2,37E-05 1,016E-03 ! DNA fragmentation involved in apoptosis GO:0006309 9 9 2,000 2,6E-05 1,089E-03 ! defense response to virus GO:0051607 9 9 2,000 2,6E-05 1,065E-03 ! regulation of nucleocytoplasmic transport GO:0046822 27 27 3,000 3,254E-05 1,304E-03 ! learning or memory GO:0007611 28 27 3,000 3,254E-05 1,276E-03 ! apoptotic mitochondrial changes GO:0008637 11 10 2,000 3,696E-05 1,419E-03 ! regulation of survival gene product expression GO:0045884 10 10 2,000 3,696E-05 1,39E-03 ! cell-substrate junction assembly GO:0007044 11 10 2,000 3,696E-05 1,362E-03 ! cell structure disassembly during apoptosis GO:0006921 10 10 2,000 3,696E-05 1,336E-03 ! regulation of erythrocyte differentiation GO:0045646 10 10 2,000 3,696E-05 1,31E-03 ! regulation of mast cell proliferation GO:0070666 28 28 3,000 3,777E-05 1,313E-03 ! regulation of protein localization GO:0032880 58 57 4,000 4,26E-05 1,454E-03 ! positive regulation of cell cycle GO:0045787 29 29 3,000 4,359E-05 1,461E-03 ! regulation of epithelial cell proliferation GO:0050678 29 29 3,000 4,359E-05 1,434E-03 ! regulation of lymphocyte proliferation GO:0050670 29 29 3,000 4,359E-05 1,409E-03 GO:0032944|regulation of mononuclear cell proliferation, GO:0070663|regulation of leukocyte proliferation, ! response to UV GO:0009411 29 29 3,000 4,359E-05 1,385E-03 ! G1 phase of mitotic cell cycle GO:0000080 12 11 2,000 5,057E-05 1,58E-03 ! positive regulation of nucleocytoplasmic transport GO:0046824 11 11 2,000 5,057E-05 1,553E-03 GO:0032388|positive regulation of intracellular transport, ! apoptotic nuclear changes GO:0030262 11 11 2,000 5,057E-05 1,528E-03 ! negative regulation of lymphocyte activation GO:0051250 11 11 2,000 5,057E-05 1,503E-03 ! regulation of intracellular transport GO:0032386 31 31 3,000 5,716E-05 1,672E-03 ! muscle organ development GO:0007517 102 100 5,000 6,074E-05 1,749E-03 ! axonogenesis GO:0007409 66 62 4,000 6,415E-05 1,819E-03 ! DNA catabolic process, endonucleolytic GO:0000737 12 12 2,000 6,71E-05 1,874E-03 ! G1 phase GO:0051318 13 12 2,000 6,71E-05 1,846E-03 ! regulation of neuron apoptosis GO:0043523 34 33 3,000 7,357E-05 1,994E-03 ! regulation of bone remodeling GO:0046850 34 34 3,000 8,296E-05 2,216E-03 ! response to peptide hormone stimulus GO:0043434 36 34 3,000 8,296E-05 2,184E-03 ! mitochondrial membrane organization GO:0007006 13 13 2,000 8,68E-05 2,253E-03 ! cell aging GO:0007569 13 13 2,000 8,68E-05 2,222E-03 ! negative regulation of leukocyte activation GO:0002695 13 13 2,000 8,68E-05 2,192E-03 ! regulation of tissue remodeling GO:0034103 35 35 3,000 9,318E-05 2,321E-03 ! cell morphogenesis involved in neuron differentiation GO:0048667 72 67 4,000 9,327E-05 2,292E-03 GO:0048812|neuron projection morphogenesis, GO:0048858|cell projection morphogenesis, ! positive regulation of cell migration GO:0030335 36 36 3,000 1,043E-04 2,529E-03 ! positive regulation of epithelial cell proliferation GO:0050679 14 14 2,000 1,099E-04 2,631E-03 ! cell part morphogenesis GO:0032990 75 70 4,000 1,151E-04 2,719E-03 ! muscle tissue development GO:0060537 72 70 4,000 1,151E-04 2,685E-03 ! axon guidance GO:0007411 39 38 3,000 1,294E-04 2,98E-03 ! regulation of transcription factor import into nucleus GO:0042990 15 15 2,000 1,367E-04 3,111E-03 ! negative regulation of cell activation GO:0050866 15 15 2,000 1,367E-04 3,074E-03 ! lymphocyte differentiation GO:0030098 39 39 3,000 1,434E-04 3,184E-03 ! positive regulation of cell motion GO:0051272 39 39 3,000 1,434E-04 3,147E-03 ! learning GO:0007612 16 16 2,000 1,675E-04 3,631E-03 ! lymphocyte proliferation GO:0046651 16 16 2,000 1,675E-04 3,589E-03 ! positive regulation of cell adhesion GO:0045785 17 17 2,000 2,024E-04 4,287E-03 ! myelination GO:0042552 17 17 2,000 2,024E-04 4,238E-03 ! dicarboxylic acid metabolic process GO:0043648 18 17 2,000 2,024E-04 4,191E-03 ! cell junction assembly GO:0034329 18 17 2,000 2,024E-04 4,144E-03 ! pigmentation GO:0043473 17 17 2,000 2,024E-04 4,099E-03 ! mitochondrion organization GO:0007005 44 43 3,000 2,108E-04 4,223E-03 ! homeostasis of number of cells GO:0048872 44 43 3,000 2,108E-04 4,178E-03 ! neuron projection development GO:0031175 85 80 4,000 2,17E-04 4,254E-03 ! lymphocyte activation GO:0046649 82 81 4,000 2,3E-04 4,462E-03 ! epidermal growth factor receptor signaling pathway GO:0007173 18 18 2,000 2,417E-04 4,639E-03 ! mononuclear cell proliferation GO:0032943 18 18 2,000 2,417E-04 4,592E-03 GO:0070661|leukocyte proliferation, ! ensheathment of neurons GO:0007272 18 18 2,000 2,417E-04 4,545E-03 GO:0008366|axon ensheathment, ! Wnt receptor signaling pathway GO:0016055 46 45 3,000 2,519E-04 4,69E-03 ! blood vessel morphogenesis GO:0048514 84 83 4,000 2,58E-04 4,754E-03 ! peptidyl-tyrosine phosphorylation GO:0018108 20 19 2,000 2,856E-04 5,211E-03 ! metanephros development GO:0001656 19 19 2,000 2,856E-04 5,16E-03 ! peripheral nervous system development GO:0007422 19 19 2,000 2,856E-04 5,11E-03 ! positive regulation of protein kinase activity GO:0045860 89 86 4,000 3,046E-04 5,398E-03 ! regulation of anatomical structure morphogenesis GO:0022603 90 86 4,000 3,046E-04 5,347E-03 ! heart development GO:0007507 90 87 4,000 3,215E-04 5,59E-03 ! nucleus organization GO:0006997 20 20 2,000 3,343E-04 5,758E-03 ! peptidyl-tyrosine modification GO:0018212 21 20 2,000 3,343E-04 5,705E-03 ! negative regulation of neuron apoptosis GO:0043524 21 20 2,000 3,343E-04 5,653E-03 ! regulation of B cell activation GO:0050864 20 20 2,000 3,343E-04 5,601E-03 ! positive regulation of transferase activity GO:0051347 91 88 4,000 3,391E-04 5,63E-03 GO:0033674|positive regulation of kinase activity, ! leukocyte differentiation GO:0002521 50 49 3,000 3,51E-04 5,776E-03 ! brain development GO:0007420 91 90 4,000 3,765E-04 6,14E-03 ! T cell activation GO:0042110 51 50 3,000 3,796E-04 6,137E-03 ! mammary gland development GO:0030879 23 21 2,000 3,881E-04 6,22E-03 ! regulation of protein import into nucleus GO:0042306 21 21 2,000 3,881E-04 6,167E-03 ! regulation of action potential in neuron GO:0019228 21 21 2,000 3,881E-04 6,114E-03 ! negative regulation of cell cycle GO:0045786 92 91 4,000 3,963E-04 6,19E-03 ! cellular amide metabolic process GO:0043603 22 22 2,000 4,472E-04 6,926E-03 ! cell junction organization GO:0034330 23 22 2,000 4,472E-04 6,869E-03 ! ovulation cycle process GO:0022602 22 22 2,000 4,472E-04 6,812E-03 ! male sex differentiation GO:0046661 22 22 2,000 4,472E-04 6,756E-03 ! neuron migration GO:0001764 22 22 2,000 4,472E-04 6,701E-03 ! blood vessel development GO:0001568 95 94 4,000 4,605E-04 6,845E-03 ! metencephalon development GO:0022037 5 5 1,000 4,703E-04 6,935E-03 ! regulation of long-term neuronal synaptic plasticity GO:0048169 5 5 1,000 4,703E-04 6,88E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 5 5 1,000 4,703E-04 6,825E-03 ! adrenal gland development GO:0030325 5 5 1,000 4,703E-04 6,772E-03 ! astrocyte differentiation GO:0048708 5 5 1,000 4,703E-04 6,72E-03 ! regulation of phospholipase A2 activity GO:0032429 5 5 1,000 4,703E-04 6,668E-03 ! fear response GO:0042596 5 5 1,000 4,703E-04 6,617E-03 ! Schwann cell differentiation GO:0014037 5 5 1,000 4,703E-04 6,567E-03 ! regulation of gliogenesis GO:0014013 5 5 1,000 4,703E-04 6,517E-03 GO:0045685|regulation of glial cell differentiation, ! response to UV-B GO:0010224 5 5 1,000 4,703E-04 6,469E-03 ! regulation of mitochondrial membrane potential GO:0051881 5 5 1,000 4,703E-04 6,421E-03 ! cellular pigmentation GO:0033059 5 5 1,000 4,703E-04 6,374E-03 ! DNA methylation GO:0006306 5 5 1,000 4,703E-04 6,327E-03 GO:0006305|DNA alkylation, ! T cell lineage commitment GO:0002360 5 5 1,000 4,703E-04 6,281E-03 ! peptidyl-lysine modification GO:0018205 5 5 1,000 4,703E-04 6,236E-03 ! negative regulation of neuroblast proliferation GO:0007406 5 5 1,000 4,703E-04 6,192E-03 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 5 5 1,000 4,703E-04 6,148E-03 ! oocyte differentiation GO:0009994 5 5 1,000 4,703E-04 6,104E-03 GO:0048599|oocyte development, ! regulation of protein homodimerization activity GO:0043496 6 5 1,000 4,703E-04 6,062E-03 ! spleen development GO:0048536 5 5 1,000 4,703E-04 6,02E-03 ! regulation of Rac protein signal transduction GO:0035020 5 5 1,000 4,703E-04 5,978E-03 ! response to nicotine GO:0035094 5 5 1,000 4,703E-04 5,937E-03 ! regulation of T cell activation GO:0050863 53 53 3,000 4,753E-04 5,959E-03 ! regulation of protein transport GO:0051223 53 53 3,000 4,753E-04 5,919E-03 GO:0070201|regulation of establishment of protein localization, ! vasculature development GO:0001944 97 96 4,000 5,075E-04 6,277E-03 ! response to virus GO:0009615 54 54 3,000 5,107E-04 6,275E-03 ! female gonad development GO:0008585 23 23 2,000 5,118E-04 6,247E-03 ! mitochondrial transport GO:0006839 24 24 2,000 5,82E-04 7,057E-03 ! regulation of action potential GO:0001508 24 24 2,000 5,82E-04 7,011E-03 ! gliogenesis GO:0042063 24 24 2,000 5,82E-04 6,966E-03 ! T cell differentiation GO:0030217 24 24 2,000 5,82E-04 6,921E-03 ! ovulation cycle GO:0042698 24 24 2,000 5,82E-04 6,876E-03 ! androgen receptor signaling pathway GO:0030521 24 24 2,000 5,82E-04 6,833E-03 ! response to hormone stimulus GO:0009725 102 100 4,000 6,122E-04 7,141E-03 ! hemopoiesis GO:0030097 104 100 4,000 6,122E-04 7,096E-03 ! cellular component disassembly GO:0022411 26 25 2,000 6,582E-04 7,582E-03 ! development of primary female sexual characteristics GO:0046545 25 25 2,000 6,582E-04 7,534E-03 GO:0046660|female sex differentiation, ! negative regulation of immune system process GO:0002683 25 25 2,000 6,582E-04 7,488E-03 ! JAK-STAT cascade GO:0007259 26 25 2,000 6,582E-04 7,442E-03 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 6 6 1,000 7,024E-04 7,893E-03 ! N-terminal protein amino acid modification GO:0031365 6 6 1,000 7,024E-04 7,845E-03 GO:0018409|peptide or protein amino-terminal blocking, ! tRNA modification GO:0006400 6 6 1,000 7,024E-04 7,798E-03 ! 'de novo' posttranslational protein folding GO:0051084 6 6 1,000 7,024E-04 7,751E-03 ! regulation of B cell proliferation GO:0030888 6 6 1,000 7,024E-04 7,705E-03 ! artery development GO:0060840 6 6 1,000 7,024E-04 7,659E-03 GO:0048844|artery morphogenesis, ! positive regulation of transcription factor import into nucleus GO:0042993 6 6 1,000 7,024E-04 7,614E-03 ! ER overload response GO:0006983 6 6 1,000 7,024E-04 7,57E-03 ! asymmetric protein localization GO:0008105 6 6 1,000 7,024E-04 7,526E-03 ! Rac protein signal transduction GO:0016601 6 6 1,000 7,024E-04 7,482E-03 ! negative regulation of ossification GO:0030279 6 6 1,000 7,024E-04 7,439E-03 ! regulation of bone resorption GO:0045124 6 6 1,000 7,024E-04 7,397E-03 ! regulation of T cell differentiation in the thymus GO:0033081 6 6 1,000 7,024E-04 7,355E-03 ! positive regulation of B cell differentiation GO:0045579 6 6 1,000 7,024E-04 7,313E-03 ! positive regulation of Ras GTPase activity GO:0032320 6 6 1,000 7,024E-04 7,272E-03 ! thymus development GO:0048538 6 6 1,000 7,024E-04 7,232E-03 ! germ cell migration GO:0008354 6 6 1,000 7,024E-04 7,191E-03 ! establishment or maintenance of apical/basal cell polarity GO:0035088 6 6 1,000 7,024E-04 7,152E-03 ! regulation of synaptic transmission, GABAergic GO:0032228 6 6 1,000 7,024E-04 7,112E-03 ! localization within membrane GO:0051668 6 6 1,000 7,024E-04 7,073E-03 ! negative regulation of cell migration GO:0030336 26 26 2,000 7,404E-04 7,416E-03 ! induction of apoptosis by intracellular signals GO:0008629 26 26 2,000 7,404E-04 7,376E-03 ! germ cell development GO:0007281 27 26 2,000 7,404E-04 7,336E-03 ! mesenchymal cell development GO:0014031 29 27 2,000 8,289E-04 8,169E-03 GO:0060485|mesenchyme development, GO:0048762|mesenchymal cell differentiation, ! regulation of lymphocyte activation GO:0051249 62 62 3,000 8,648E-04 8,478E-03 ! protein amino acid autophosphorylation GO:0046777 28 28 2,000 9,238E-04 9,008E-03 ! angiogenesis GO:0001525 65 64 3,000 9,75E-04 9,458E-03 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 7 7 1,000 9,789E-04 9,446E-03 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 7 7 1,000 9,789E-04 9,397E-03 ! positive regulation of GTPase activity GO:0043547 7 7 1,000 9,789E-04 9,348E-03 ! hair follicle morphogenesis GO:0031069 7 7 1,000 9,789E-04 9,3E-03 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 7 7 1,000 9,789E-04 9,252E-03 ! digestive system development GO:0055123 7 7 1,000 9,789E-04 9,205E-03 GO:0048546|digestive tract morphogenesis, GO:0048547|gut morphogenesis, ! vascular endothelial growth factor receptor signaling pathway GO:0048010 7 7 1,000 9,789E-04 9,158E-03 ! positive regulation of survival gene product expression GO:0045885 7 7 1,000 9,789E-04 9,112E-03 ! regulation of skeletal muscle fiber development GO:0048742 7 7 1,000 9,789E-04 9,066E-03 ! alpha-beta T cell differentiation GO:0046632 7 7 1,000 9,789E-04 9,021E-03 ! NLS-bearing substrate import into nucleus GO:0006607 7 7 1,000 9,789E-04 8,976E-03 ! autonomic nervous system development GO:0048483 7 7 1,000 9,789E-04 8,931E-03 ! natural killer cell activation GO:0030101 7 7 1,000 9,789E-04 8,887E-03 ! response to gamma radiation GO:0010332 8 7 1,000 9,789E-04 8,844E-03 ! branching morphogenesis of a tube GO:0048754 29 29 2,000 1,025E-03 9,218E-03 ! positive regulation of protein transport GO:0051222 29 29 2,000 1,025E-03 9,174E-03 ! response to reactive oxygen species GO:0000302 31 30 2,000 1,134E-03 0,01009431 ! regulation of ossification GO:0030278 30 30 2,000 1,134E-03 0,01004578 ! striated muscle tissue development GO:0014706 69 67 3,000 1,158E-03 0,01021474 ! negative regulation of cell differentiation GO:0045596 68 67 3,000 1,158E-03 0,01016609 ! aging GO:0007568 32 31 2,000 1,249E-03 0,01091049 ! regulation of myeloid cell differentiation GO:0045637 32 31 2,000 1,249E-03 0,01085902 ! negative regulation of cell motion GO:0051271 31 31 2,000 1,249E-03 0,01080804 ! regulation of leukocyte activation GO:0002694 69 69 3,000 1,293E-03 0,01113771 ! regulation of skeletal muscle tissue development GO:0048641 8 8 1,000 1,299E-03 0,01113882 ! 'de novo' protein folding GO:0006458 8 8 1,000 1,299E-03 0,01108725 ! negative regulation of bone remodeling GO:0046851 8 8 1,000 1,299E-03 0,01103616 ! regulation of neuronal synaptic plasticity GO:0048168 8 8 1,000 1,299E-03 0,01098553 ! lipid localization GO:0010876 8 8 1,000 1,299E-03 0,01093537 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 8 8 1,000 1,299E-03 0,01088567 ! T cell selection GO:0045058 8 8 1,000 1,299E-03 0,01083641 ! fructose metabolic process GO:0006000 8 8 1,000 1,299E-03 0,0107876 ! negative regulation of mitotic cell cycle GO:0045930 9 8 1,000 1,299E-03 0,01073922 ! alpha-beta T cell activation GO:0046631 8 8 1,000 1,299E-03 0,01069128 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 32 32 2,000 1,372E-03 0,01123499 ! morphogenesis of a branching structure GO:0001763 32 32 2,000 1,372E-03 0,01118528 ! regulation of lymphocyte differentiation GO:0045619 32 32 2,000 1,372E-03 0,011136 ! kidney development GO:0001822 32 32 2,000 1,372E-03 0,01108716 ! regulation of cell activation GO:0050865 71 71 3,000 1,439E-03 0,01157936 ! regulation of angiogenesis GO:0045765 35 34 2,000 1,639E-03 0,01313082 ! lactation GO:0007595 10 9 1,000 1,663E-03 0,01327012 ! negative regulation of cell cycle process GO:0010948 9 9 1,000 1,663E-03 0,01321292 ! regulation of nitric-oxide synthase activity GO:0050999 9 9 1,000 1,663E-03 0,01315621 ! response to alkaloid GO:0043279 10 9 1,000 1,663E-03 0,01309999 ! regulation of interleukin-2 biosynthetic process GO:0045076 9 9 1,000 1,663E-03 0,01304424 ! response to ethanol GO:0045471 9 9 1,000 1,663E-03 0,01298897 ! activation of pro-apoptotic gene products GO:0008633 9 9 1,000 1,663E-03 0,01293417 ! cerebral cortex development GO:0021987 9 9 1,000 1,663E-03 0,01287982 ! branching involved in ureteric bud morphogenesis GO:0001658 9 9 1,000 1,663E-03 0,01282593 GO:0060675|ureteric bud morphogenesis, ! negative regulation of protein import into nucleus GO:0042308 9 9 1,000 1,663E-03 0,01277249 ! positive regulation of protein import into nucleus GO:0042307 9 9 1,000 1,663E-03 0,01271949 ! T cell differentiation in the thymus GO:0033077 9 9 1,000 1,663E-03 0,01266693 ! histone acetylation GO:0016573 9 9 1,000 1,663E-03 0,0126148 ! negative regulation of tissue remodeling GO:0034104 9 9 1,000 1,663E-03 0,0125631 ! regulation of blood vessel endothelial cell migration GO:0043535 9 9 1,000 1,663E-03 0,01251183 ! regulation of cyclin-dependent protein kinase activity GO:0000079 35 35 2,000 1,784E-03 0,01336228 ! multicellular organism reproduction GO:0032504 36 35 2,000 1,784E-03 0,01330818 GO:0048609|reproductive process in a multicellular organism, ! positive regulation of phosphorylation GO:0042327 35 35 2,000 1,784E-03 0,01325452 ! positive regulation of multicellular organismal process GO:0051240 76 76 3,000 1,852E-03 0,01370794 ! oxygen and reactive oxygen species metabolic process GO:0006800 37 36 2,000 1,936E-03 0,0142739 ! positive regulation of phosphorus metabolic process GO:0010562 36 36 2,000 1,936E-03 0,01421704 GO:0045937|positive regulation of phosphate metabolic process, ! female pregnancy GO:0007565 37 36 2,000 1,936E-03 0,01416062 ! gonad development GO:0008406 36 36 2,000 1,936E-03 0,01410465 ! neuron maturation GO:0042551 10 10 1,000 2,07E-03 0,01501857 ! negative regulation of nucleocytoplasmic transport GO:0046823 10 10 1,000 2,07E-03 0,01495967 ! glial cell development GO:0021782 10 10 1,000 2,07E-03 0,01490124 ! induction of apoptosis via death domain receptors GO:0008625 10 10 1,000 2,07E-03 0,01484325 ! epidermis morphogenesis GO:0048730 10 10 1,000 2,07E-03 0,01478572 ! neuromuscular junction development GO:0007528 10 10 1,000 2,07E-03 0,01472863 ! regulation of protein binding GO:0043393 11 10 1,000 2,07E-03 0,01467199 ! intermediate filament cytoskeleton organization GO:0045104 10 10 1,000 2,07E-03 0,01461577 ! regulation of B cell differentiation GO:0045577 10 10 1,000 2,07E-03 0,01455999 ! gland morphogenesis GO:0022612 10 10 1,000 2,07E-03 0,01450462 ! epithelial to mesenchymal transition GO:0001837 10 10 1,000 2,07E-03 0,01444968 ! gut development GO:0048565 10 10 1,000 2,07E-03 0,01439516 ! positive regulation of neuron apoptosis GO:0043525 10 10 1,000 2,07E-03 0,01434104 ! negative regulation of homeostatic process GO:0032845 10 10 1,000 2,07E-03 0,01428733 ! negative regulation of protein kinase activity GO:0006469 37 37 2,000 2,097E-03 0,01441949 ! response to drug GO:0042493 37 37 2,000 2,097E-03 0,01436588 ! negative regulation of kinase activity GO:0033673 38 38 2,000 2,265E-03 0,01546379 ! cell-matrix adhesion GO:0007160 39 38 2,000 2,265E-03 0,01540673 ! urogenital system development GO:0001655 38 38 2,000 2,265E-03 0,01535008 ! steroid hormone receptor signaling pathway GO:0030518 38 38 2,000 2,265E-03 0,01529386 ! tube development GO:0035295 83 81 3,000 2,341E-03 0,0157482 ! activation of MAPK activity GO:0000187 39 39 2,000 2,442E-03 0,01636775 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 11 11 1,000 2,519E-03 0,01681782 ! protein amino acid acetylation GO:0006473 11 11 1,000 2,519E-03 0,01675711 ! T cell proliferation GO:0042098 11 11 1,000 2,519E-03 0,01669683 ! negative regulation of endothelial cell proliferation GO:0001937 11 11 1,000 2,519E-03 0,01663698 ! regulation of viral genome replication GO:0045069 11 11 1,000 2,519E-03 0,01657756 ! spinal cord development GO:0021510 11 11 1,000 2,519E-03 0,01651857 ! positive regulation of nitric oxide biosynthetic process GO:0045429 11 11 1,000 2,519E-03 0,01645999 ! intermediate filament-based process GO:0045103 11 11 1,000 2,519E-03 0,01640183 ! regulation of interleukin-2 production GO:0032663 11 11 1,000 2,519E-03 0,01634408 ! regulation of monooxygenase activity GO:0032768 11 11 1,000 2,519E-03 0,01628673 ! oogenesis GO:0048477 11 11 1,000 2,519E-03 0,01622978 ! hindbrain development GO:0030902 11 11 1,000 2,519E-03 0,01617323 ! negative regulation of transferase activity GO:0051348 40 40 2,000 2,627E-03 0,01681388 ! DNA catabolic process GO:0006308 41 40 2,000 2,627E-03 0,0167557 ! intracellular receptor-mediated signaling pathway GO:0030522 40 40 2,000 2,627E-03 0,01669792 ! regulation of cellular localization GO:0060341 86 85 3,000 2,792E-03 0,0176824 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 12 12 1,000 3,009E-03 0,01899085 ! initiation of viral infection GO:0019059 12 12 1,000 3,009E-03 0,01892604 ! osteoblast differentiation GO:0001649 12 12 1,000 3,009E-03 0,01886166 ! male gonad development GO:0008584 12 12 1,000 3,009E-03 0,01879772 ! renal system process GO:0003014 12 12 1,000 3,009E-03 0,01873422 ! regulation of steroid metabolic process GO:0019218 12 12 1,000 3,009E-03 0,01867114 ! fibroblast growth factor receptor signaling pathway GO:0008543 12 12 1,000 3,009E-03 0,01860848 ! pallium development GO:0021543 13 12 1,000 3,009E-03 0,01854625 ! regulation of chromosome organization GO:0033044 12 12 1,000 3,009E-03 0,01848443 ! somitogenesis GO:0001756 13 12 1,000 3,009E-03 0,01842302 ! regulation of mitotic metaphase/anaphase transition GO:0030071 13 12 1,000 3,009E-03 0,01836201 ! cell-substrate adhesion GO:0031589 43 42 2,000 3,023E-03 0,0183893 ! development of primary sexual characteristics GO:0045137 42 42 2,000 3,023E-03 0,01832881 ! response to protein stimulus GO:0051789 42 42 2,000 3,023E-03 0,01826872 ! forebrain development GO:0030900 43 42 2,000 3,023E-03 0,01820902 ! reproductive structure development GO:0048608 43 43 2,000 3,234E-03 0,01941601 ! regulation of Ras protein signal transduction GO:0046578 90 90 3,000 3,435E-03 0,02055336 ! G2/M transition of mitotic cell cycle GO:0000086 13 13 1,000 3,54E-03 0,02111483 ! positive regulation of JAK-STAT cascade GO:0046427 13 13 1,000 3,54E-03 0,02104672 ! regeneration GO:0031099 13 13 1,000 3,54E-03 0,02097904 ! post-embryonic development GO:0009791 14 13 1,000 3,54E-03 0,0209118 ! patterning of blood vessels GO:0001569 13 13 1,000 3,54E-03 0,02084499 ! regulation of DNA recombination GO:0000018 13 13 1,000 3,54E-03 0,02077861 ! regulation of nitric oxide biosynthetic process GO:0045428 13 13 1,000 3,54E-03 0,02071264 ! response to corticosteroid stimulus GO:0031960 13 13 1,000 3,54E-03 0,0206471 GO:0051384|response to glucocorticoid stimulus, ! actin filament bundle formation GO:0051017 13 13 1,000 3,54E-03 0,02058196 ! ureteric bud development GO:0001657 13 13 1,000 3,54E-03 0,02051724 ! regulation of endothelial cell migration GO:0010594 13 13 1,000 3,54E-03 0,02045292 ! response to endoplasmic reticulum stress GO:0034976 13 13 1,000 3,54E-03 0,02038901 ! negative regulation of protein kinase cascade GO:0010741 13 13 1,000 3,54E-03 0,02032549 ! regulation of viral reproduction GO:0050792 13 13 1,000 3,54E-03 0,02026237 ! negative regulation of intracellular transport GO:0032387 13 13 1,000 3,54E-03 0,02019964 ! negative regulation of myeloid cell differentiation GO:0045638 13 13 1,000 3,54E-03 0,02013729 ! response to cytokine stimulus GO:0034097 13 13 1,000 3,54E-03 0,02007533 ! camera-type eye morphogenesis GO:0048593 13 13 1,000 3,54E-03 0,02001375 ! tissue homeostasis GO:0001894 13 13 1,000 3,54E-03 0,01995255 GO:0048871|multicellular organismal homeostasis, ! tube morphogenesis GO:0035239 47 46 2,000 3,921E-03 0,02202901 ! cellular response to hormone stimulus GO:0032870 48 46 2,000 3,921E-03 0,02196205 ! protein amino acid acylation GO:0043543 14 14 1,000 4,112E-03 0,02296402 ! hair cycle GO:0042633 14 14 1,000 4,112E-03 0,02289464 GO:0022404|molting cycle process, GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042303|molting cycle, ! negative regulation of epithelial cell proliferation GO:0050680 14 14 1,000 4,112E-03 0,02282568 ! multicellular organismal response to stress GO:0033555 14 14 1,000 4,112E-03 0,02275714 ! response to organic cyclic substance GO:0014070 15 14 1,000 4,112E-03 0,022689 ! DNA modification GO:0006304 14 14 1,000 4,112E-03 0,02262127 ! collagen fibril organization GO:0030199 14 14 1,000 4,112E-03 0,02255395 ! positive regulation of inflammatory response GO:0050729 14 14 1,000 4,112E-03 0,02248702 ! sex differentiation GO:0007548 47 47 2,000 4,167E-03 0,02272381 ! rhythmic process GO:0048511 47 47 2,000 4,167E-03 0,02265678 ! actin filament organization GO:0007015 50 48 2,000 4,424E-03 0,02397906 ! ossification GO:0001503 50 49 2,000 4,689E-03 0,02534428 GO:0060348|bone development, ! skeletal muscle tissue development GO:0007519 50 49 2,000 4,689E-03 0,02527018 GO:0060538|skeletal muscle organ development, ! positive regulation of fibroblast proliferation GO:0048146 15 15 1,000 4,723E-03 0,02537965 ! striated muscle cell differentiation GO:0051146 16 15 1,000 4,723E-03 0,02530587 ! insulin receptor signaling pathway GO:0008286 17 15 1,000 4,723E-03 0,02523252 ! ovarian follicle development GO:0001541 15 15 1,000 4,723E-03 0,02515959 ! ER-nuclear signaling pathway GO:0006984 15 15 1,000 4,723E-03 0,02508709 ! response to ionizing radiation GO:0010212 16 15 1,000 4,723E-03 0,025015 ! positive regulation of B cell activation GO:0050871 15 15 1,000 4,723E-03 0,02494332 ! protein homooligomerization GO:0051260 15 15 1,000 4,723E-03 0,02487206 ! anti-apoptosis GO:0006916 100 99 3,000 4,834E-03 0,02538242 ! regulation of DNA metabolic process GO:0051052 51 50 2,000 4,964E-03 0,02599258 ! regulation of neurogenesis GO:0050767 51 50 2,000 4,964E-03 0,02591894 ! response to other organism GO:0051707 101 100 3,000 5,01E-03 0,02608315 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 16 16 1,000 5,374E-03 0,02790064 ! regulation of synaptic plasticity GO:0048167 16 16 1,000 5,374E-03 0,02782227 ! positive regulation of mitosis GO:0045840 16 16 1,000 5,374E-03 0,02774433 GO:0051785|positive regulation of nuclear division, ! cellular response to reactive oxygen species GO:0034614 16 16 1,000 5,374E-03 0,02766683 ! segmentation GO:0035282 17 16 1,000 5,374E-03 0,02758977 ! positive regulation of cell development GO:0010720 16 16 1,000 5,374E-03 0,02751313 ! cell fate commitment GO:0045165 52 52 2,000 5,543E-03 0,02830046 ! regulation of fibroblast proliferation GO:0048145 17 17 1,000 6,064E-03 0,03087189 ! glucose transport GO:0015758 17 17 1,000 6,064E-03 0,03078685 ! development of primary male sexual characteristics GO:0046546 17 17 1,000 6,064E-03 0,03070227 ! response to toxin GO:0009636 18 17 1,000 6,064E-03 0,03061815 ! negative regulation of cell development GO:0010721 18 17 1,000 6,064E-03 0,0305345 GO:0050768|negative regulation of neurogenesis, ! regulation of oxidoreductase activity GO:0051341 17 17 1,000 6,064E-03 0,0304513 ! regulation of osteoblast differentiation GO:0045667 17 17 1,000 6,064E-03 0,03036855 ! liver development GO:0001889 17 17 1,000 6,064E-03 0,03028625 ! sulfur metabolic process GO:0006790 55 54 2,000 6,161E-03 0,03069044 ! meiosis I GO:0007127 18 18 1,000 6,792E-03 0,03373829 ! hexose transport GO:0008645 18 18 1,000 6,792E-03 0,0336476 GO:0015749|monosaccharide transport, ! telencephalon development GO:0021537 19 18 1,000 6,792E-03 0,03355739 ! negative regulation of MAP kinase activity GO:0043407 18 18 1,000 6,792E-03 0,03346766 ! B cell differentiation GO:0030183 18 18 1,000 6,792E-03 0,03337842 ! reproductive developmental process GO:0003006 56 56 2,000 6,819E-03 0,03342451 ! extracellular structure organization GO:0043062 56 56 2,000 6,819E-03 0,03333585 ! regulation of nervous system development GO:0051960 57 56 2,000 6,819E-03 0,03324766 ! regulation of binding GO:0051098 60 57 2,000 7,163E-03 0,03483244 ! DNA damage checkpoint GO:0000077 19 19 1,000 7,557E-03 0,03665149 ! glial cell differentiation GO:0010001 19 19 1,000 7,557E-03 0,03655529 ! regulation of JAK-STAT cascade GO:0046425 19 19 1,000 7,557E-03 0,03645959 ! regulation of endothelial cell proliferation GO:0001936 19 19 1,000 7,557E-03 0,0363644 ! positive regulation of T cell proliferation GO:0042102 19 19 1,000 7,557E-03 0,0362697 ! regulation of striated muscle tissue development GO:0016202 20 19 1,000 7,557E-03 0,03617549 ! multicellular organismal metabolic process GO:0044236 19 19 1,000 7,557E-03 0,03608177 ! cellular response to oxidative stress GO:0034599 19 19 1,000 7,557E-03 0,03598854 ! regulation of protein stability GO:0031647 19 19 1,000 7,557E-03 0,03589579 ! eye morphogenesis GO:0048592 19 19 1,000 7,557E-03 0,03580351 ! response to heat GO:0009408 19 19 1,000 7,557E-03 0,0357117 ! regulation of cell development GO:0060284 60 59 2,000 7,881E-03 0,0371497 ! immune effector process GO:0002252 59 59 2,000 7,881E-03 0,03705493 ! regulation of muscle development GO:0048634 21 20 1,000 8,36E-03 0,03920257 ! establishment or maintenance of cell polarity GO:0007163 21 20 1,000 8,36E-03 0,03910307 ! chromatin remodeling GO:0006338 20 20 1,000 8,36E-03 0,03900408 ! female gamete generation GO:0007292 20 20 1,000 8,36E-03 0,03890558 ! RNA modification GO:0009451 20 20 1,000 8,36E-03 0,03880758 ! regulation of protein amino acid phosphorylation GO:0001932 62 61 2,000 8,641E-03 0,04001373 ! mitotic sister chromatid segregation GO:0000070 21 21 1,000 9,199E-03 0,04248887 ! positive regulation of adenylate cyclase activity GO:0045762 21 21 1,000 9,199E-03 0,04238265 GO:0051349|positive regulation of lyase activity, GO:0031281|positive regulation of cyclase activity, ! DNA integrity checkpoint GO:0031570 21 21 1,000 9,199E-03 0,04227696 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 21 21 1,000 9,199E-03 0,04217179 ! cellular response to insulin stimulus GO:0032869 23 21 1,000 9,199E-03 0,04206715 ! negative regulation of protein transport GO:0051224 21 21 1,000 9,199E-03 0,04196302 ! positive regulation of transcription factor activity GO:0051091 22 22 1,000 0,01007376 0,04584183 GO:0090047|positive regulation of transcription regulator activity, ! sister chromatid segregation GO:0000819 22 22 1,000 0,01007376 0,04572892 ! positive regulation of lymphocyte proliferation GO:0050671 22 22 1,000 0,01007376 0,04561657 GO:0032946|positive regulation of mononuclear cell proliferation, GO:0070665|positive regulation of leukocyte proliferation, GO:0070668|positive regulation of mast cell proliferation, ! spindle organization GO:0007051 22 22 1,000 0,01007376 0,04550476 ! biopolymer methylation GO:0043414 22 22 1,000 0,01007376 0,0453935 GO:0032259|methylation, ! positive regulation of lymphocyte differentiation GO:0045621 22 22 1,000 0,01007376 0,04528279 ! cytokinesis GO:0000910 23 22 1,000 0,01007376 0,04517261 ! response to hydrogen peroxide GO:0042542 24 23 1,000 0,01098443 0,04913664 ! viral infectious cycle GO:0019058 23 23 1,000 0,01098443 0,04901767 ! response to estrogen stimulus GO:0043627 23 23 1,000 0,01098443 0,04889927 ! mitotic cell cycle checkpoint GO:0007093 24 23 1,000 0,01098443 0,04878144 ! induction of apoptosis by extracellular signals GO:0008624 23 23 1,000 0,01098443 0,04866417 ! endocrine system development GO:0035270 23 23 1,000 0,01098443 0,04854747 ! calcium-mediated signaling GO:0019722 23 23 1,000 0,01098443 0,04843133 ! cell projection assembly GO:0030031 25 23 1,000 0,01098443 0,04831574 ! regulation of cell size GO:0008361 68 68 2,000 0,01163092 0,05103759 ! epithelial tube morphogenesis GO:0060562 25 24 1,000 0,0119301 0,05222605 ! glucan metabolic process GO:0044042 25 24 1,000 0,0119301 0,05210229 GO:0006073|cellular glucan metabolic process, GO:0005977|glycogen metabolic process, ! positive regulation of transport GO:0051050 71 70 2,000 0,01258154 0,05481743 ! wound healing GO:0042060 74 70 2,000 0,01258154 0,05468815 ! growth GO:0040007 70 70 2,000 0,01258154 0,05455947 ! positive regulation of DNA binding GO:0043388 26 25 1,000 0,01291026 0,05585355 ! calcium ion homeostasis GO:0055074 71 71 2,000 0,01307313 0,05642571 GO:0006874|cellular calcium ion homeostasis, ! sensory organ development GO:0007423 72 72 2,000 0,01357563 0,05845767 ! positive regulation of hydrolase activity GO:0051345 72 72 2,000 0,01357563 0,05832141 ! positive regulation of binding GO:0051099 27 26 1,000 0,01392442 0,0596807 ! positive regulation of defense response GO:0031349 26 26 1,000 0,01392442 0,05954223 ! glycolysis GO:0006096 26 26 1,000 0,01392442 0,0594044 ! positive regulation of cytokine biosynthetic process GO:0042108 26 26 1,000 0,01392442 0,0592672 ! regulation of T cell differentiation GO:0045580 26 26 1,000 0,01392442 0,05913064 ! pigment metabolic process GO:0042440 26 26 1,000 0,01392442 0,05899471 ! response to insulin stimulus GO:0032868 28 26 1,000 0,01392442 0,0588594 ! synapse organization GO:0050808 26 26 1,000 0,01392442 0,05872471 ! energy reserve metabolic process GO:0006112 28 27 1,000 0,01497206 0,06299887 ! cell growth GO:0016049 27 27 1,000 0,01497206 0,06285536 ! response to oxidative stress GO:0006979 76 75 2,000 0,01514889 0,06345321 ! carbohydrate transport GO:0008643 28 28 1,000 0,01605269 0,06708642 ! keratinocyte differentiation GO:0030216 28 28 1,000 0,01605269 0,06693464 ! histone modification GO:0016570 28 28 1,000 0,01605269 0,06678355 ! developmental growth GO:0048589 28 28 1,000 0,01605269 0,06663313 ! cellular metal ion homeostasis GO:0006875 77 77 2,000 0,01625285 0,06731235 ! regulation of protein modification process GO:0031399 79 78 2,000 0,01682143 0,06951098 ! positive regulation of protein kinase cascade GO:0010740 79 78 2,000 0,01682143 0,06935547 ! metal ion homeostasis GO:0055065 78 78 2,000 0,01682143 0,06920066 ! viral reproductive process GO:0022415 29 29 1,000 0,01716583 0,07046017 ! tRNA processing GO:0008033 29 29 1,000 0,01716583 0,07030359 ! regulation of gene expression, epigenetic GO:0040029 29 29 1,000 0,01716583 0,07014771 ! covalent chromatin modification GO:0016569 29 29 1,000 0,01716583 0,06999252 ! activation of phospholipase C activity GO:0007202 30 30 1,000 0,01831097 0,07449696 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of response to external stimulus GO:0032103 30 30 1,000 0,01831097 0,07433287 ! positive regulation of protein amino acid phosphorylation GO:0001934 30 30 1,000 0,01831097 0,0741695 ! response to temperature stimulus GO:0009266 30 30 1,000 0,01831097 0,07400685 ! regulation of inflammatory response GO:0050727 30 30 1,000 0,01831097 0,07384491 ! vesicle organization GO:0016050 30 30 1,000 0,01831097 0,07368368 ! establishment of organelle localization GO:0051656 31 30 1,000 0,01831097 0,07352315 ! MAPKKK cascade GO:0000165 82 81 2,000 0,01859387 0,07449676 ! skeletal muscle fiber development GO:0048741 31 31 1,000 0,01948765 0,07790834 ! B cell activation GO:0042113 31 31 1,000 0,01948765 0,07773971 ! positive regulation of phospholipase activity GO:0010518 31 31 1,000 0,01948765 0,0775718 ! regulation of DNA replication GO:0006275 32 31 1,000 0,01948765 0,07740462 ! camera-type eye development GO:0043010 31 31 1,000 0,01948765 0,07723816 ! extracellular matrix organization GO:0030198 31 31 1,000 0,01948765 0,07707241 ! epidermal cell differentiation GO:0009913 31 31 1,000 0,01948765 0,07690738 ! cellular amino acid derivative metabolic process GO:0006575 87 84 2,000 0,02046669 0,08059853 ! negative regulation of cell growth GO:0030308 32 32 1,000 0,02069539 0,08132538 ! muscle fiber development GO:0048747 32 32 1,000 0,02069539 0,08115235 ! glucose catabolic process GO:0006007 32 32 1,000 0,02069539 0,08098005 ! regulation of phospholipase activity GO:0010517 32 32 1,000 0,02069539 0,08080848 ! cell maturation GO:0048469 32 32 1,000 0,02069539 0,08063764 ! positive regulation of lipase activity GO:0060193 32 32 1,000 0,02069539 0,08046752 ! positive regulation of cell differentiation GO:0045597 87 85 2,000 0,02111333 0,08191971 ! hexose metabolic process GO:0019318 87 86 2,000 0,02177116 0,08429464 ! negative regulation of cell size GO:0045792 33 33 1,000 0,02193371 0,08474597 ! activation of protein kinase activity GO:0032147 35 33 1,000 0,02193371 0,08456868 ! regulation of neuron differentiation GO:0045664 34 33 1,000 0,02193371 0,08439213 ! regulation of synaptic transmission GO:0050804 33 33 1,000 0,02193371 0,08421631 ! response to metal ion GO:0010038 34 34 1,000 0,02320215 0,08890138 ! ear development GO:0043583 34 34 1,000 0,02320215 0,08871694 ! muscle cell differentiation GO:0042692 35 34 1,000 0,02320215 0,08853326 ! cellular polysaccharide metabolic process GO:0044264 35 34 1,000 0,02320215 0,08835034 ! regulation of lipid metabolic process GO:0019216 34 34 1,000 0,02320215 0,08816817 ! secondary metabolic process GO:0019748 34 34 1,000 0,02320215 0,08798676 ! viral reproduction GO:0016032 34 34 1,000 0,02320215 0,08780608 ! cellular di-, tri-valent inorganic cation homeostasis GO:0030005 89 89 2,000 0,02381188 0,0899289 ! regulation of cytokine biosynthetic process GO:0042035 35 35 1,000 0,02450025 0,09233937 ! response to steroid hormone stimulus GO:0048545 35 35 1,000 0,02450025 0,09215093 ! di-, tri-valent inorganic cation homeostasis GO:0055066 91 91 2,000 0,0252284 0,09469643 ! response to inorganic substance GO:0010035 36 36 1,000 0,02582754 0,09674829 ! regulation of mitosis GO:0007088 37 36 1,000 0,02582754 0,09655205 GO:0051783|regulation of nuclear division, ! positive regulation of organelle organization GO:0010638 36 36 1,000 0,02582754 0,0963566 ! integrin-mediated signaling pathway GO:0007229 36 36 1,000 0,02582754 0,09616194 ! regulation of transmission of nerve impulse GO:0051969 36 36 1,000 0,02582754 0,09596806 ! regulation of lipase activity GO:0060191 36 36 1,000 0,02582754 0,09577497 ! fatty acid metabolic process GO:0006631 93 92 2,000 0,02595347 0,09604868 ! regulation of adenylate cyclase activity GO:0045761 37 37 1,000 0,02718358 0,10039949 GO:0031279|regulation of cyclase activity, GO:0051339|regulation of lyase activity, ! regulation of transcription factor activity GO:0051090 38 37 1,000 0,02718358 0,10019869 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 37 37 1,000 0,02718358 0,09999869 GO:0051327|M phase of meiotic cell cycle, ! lung development GO:0030324 38 37 1,000 0,02718358 0,09979949 ! eye development GO:0001654 37 37 1,000 0,02718358 0,09960108 ! negative regulation of growth GO:0045926 37 37 1,000 0,02718358 0,09940346 ! DNA damage response, signal transduction GO:0042770 37 37 1,000 0,02718358 0,09920662 ! regulation of Rho protein signal transduction GO:0035023 37 37 1,000 0,02718358 0,09901056 ! pattern specification process GO:0007389 96 94 2,000 0,02743719 0,09973718 ! epidermis development GO:0008544 94 94 2,000 0,02743719 0,09954084 ! chromosome segregation GO:0007059 38 38 1,000 0,02856792 0,10343946 ! hexose catabolic process GO:0019320 38 38 1,000 0,02856792 0,10323663 ! meiotic cell cycle GO:0051321 38 38 1,000 0,02856792 0,10303461 ! regulation of neurological system process GO:0031644 38 38 1,000 0,02856792 0,10283337 ! regulation of cAMP biosynthetic process GO:0030817 39 39 1,000 0,02998012 0,10770636 ! positive regulation of protein modification process GO:0031401 39 39 1,000 0,02998012 0,10749681 ! respiratory tube development GO:0030323 40 39 1,000 0,02998012 0,10728808 ! response to unfolded protein GO:0006986 39 39 1,000 0,02998012 0,10708016 ! cytokine-mediated signaling pathway GO:0019221 39 39 1,000 0,02998012 0,10687304 ! regulation of MAPKKK cascade GO:0043408 41 39 1,000 0,02998012 0,10666672 ! positive regulation of T cell activation GO:0050870 39 39 1,000 0,02998012 0,1064612 ! respiratory system development GO:0060541 40 39 1,000 0,02998012 0,10625646 ! developmental maturation GO:0021700 39 39 1,000 0,02998012 0,10605252 ! protein oligomerization GO:0051259 39 39 1,000 0,02998012 0,10584935 ! endocytosis GO:0006897 99 98 2,000 0,03053877 0,1076156 GO:0010324|membrane invagination, ! ectoderm development GO:0007398 99 99 2,000 0,03134204 0,11023547 ! regulation of cAMP metabolic process GO:0030814 40 40 1,000 0,03141973 0,11029823 ! organelle localization GO:0051640 41 40 1,000 0,03141973 0,11008854 ! negative regulation of transcription from RNA polymerase II promoter GO:0000122 103 100 2,000 0,03215644 0,112456 ! regulation of nucleotide biosynthetic process GO:0030808 41 41 1,000 0,03288633 0,11479074 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! cell cycle checkpoint GO:0000075 42 41 1,000 0,03288633 0,11457374 ! elevation of cytosolic calcium ion concentration GO:0007204 41 41 1,000 0,03288633 0,11435756 ! regulation of caspase activity GO:0043281 41 41 1,000 0,03288633 0,1141422 ! regulation of Ras GTPase activity GO:0032318 41 41 1,000 0,03288633 0,11392765 ! monosaccharide catabolic process GO:0046365 41 41 1,000 0,03288633 0,1137139 ! regulation of cyclic nucleotide metabolic process GO:0030799 42 42 1,000 0,03437948 0,11865428 ! regulation of endopeptidase activity GO:0052548 42 42 1,000 0,03437948 0,1184325 ! cytosolic calcium ion homeostasis GO:0051480 42 42 1,000 0,03437948 0,11821154 ! negative regulation of ligase activity GO:0051352 43 42 1,000 0,03437948 0,11799141 GO:0051444|negative regulation of ubiquitin-protein ligase activity, GO:0051436|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle, ! one-carbon metabolic process GO:0006730 42 42 1,000 0,03437948 0,11777209 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 42 42 1,000 0,03437948 0,11755359 ! rRNA transcription GO:0009303 5 5 0,000 0,03441022 0,11744081 ! positive regulation of protein ubiquitination GO:0031398 5 5 0,000 0,03441022 0,11722373 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 5 5 0,000 0,03441022 0,11700745 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 5 5 0,000 0,03441022 0,11679196 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! neuron fate specification GO:0048665 5 5 0,000 0,03441022 0,11657727 ! hemoglobin biosynthetic process GO:0042541 5 5 0,000 0,03441022 0,11636337 ! reproductive cellular process GO:0048610 5 5 0,000 0,03441022 0,11615025 ! positive regulation of glucose metabolic process GO:0010907 5 5 0,000 0,03441022 0,11593791 ! negative regulation of blood pressure GO:0045776 6 5 0,000 0,03441022 0,11572634 ! prostate gland development GO:0030850 5 5 0,000 0,03441022 0,11551555 ! water transport GO:0006833 5 5 0,000 0,03441022 0,11530552 GO:0042044|fluid transport, ! forebrain regionalization GO:0021871 5 5 0,000 0,03441022 0,11509625 ! DNA synthesis during DNA repair GO:0000731 5 5 0,000 0,03441022 0,11488775 ! positive regulation of B cell proliferation GO:0030890 5 5 0,000 0,03441022 0,11467999 ! glycerol metabolic process GO:0006071 5 5 0,000 0,03441022 0,11447299 ! regulation of cellular amine metabolic process GO:0033238 5 5 0,000 0,03441022 0,11426673 GO:0042053|regulation of dopamine metabolic process, GO:0042069|regulation of catecholamine metabolic process, ! meiotic prophase I GO:0007128 5 5 0,000 0,03441022 0,11406122 GO:0051324|prophase, ! cell volume homeostasis GO:0006884 5 5 0,000 0,03441022 0,11385644 ! regulation of epidermal growth factor receptor activity GO:0007176 5 5 0,000 0,03441022 0,11365239 GO:0010469|regulation of receptor activity, ! filopodium assembly GO:0046847 7 5 0,000 0,03441022 0,11344908 GO:0030035|microspike assembly, ! CTP metabolic process GO:0046036 5 5 0,000 0,03441022 0,11324649 GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, GO:0006241|CTP biosynthetic process, ! Golgi to endosome transport GO:0006895 5 5 0,000 0,03441022 0,11304463 ! GTP metabolic process GO:0046039 5 5 0,000 0,03441022 0,11284348 ! establishment of tissue polarity GO:0007164 5 5 0,000 0,03441022 0,11264305 ! mRNA stabilization GO:0048255 5 5 0,000 0,03441022 0,11244333 GO:0043489|RNA stabilization, ! positive regulation of cell-cell adhesion GO:0022409 5 5 0,000 0,03441022 0,11224431 ! regulation of neurotransmitter secretion GO:0046928 5 5 0,000 0,03441022 0,112046 GO:0001956|positive regulation of neurotransmitter secretion, ! neurotransmitter uptake GO:0001504 5 5 0,000 0,03441022 0,11184839 ! social behavior GO:0035176 5 5 0,000 0,03441022 0,11165147 ! macrophage chemotaxis GO:0048246 6 5 0,000 0,03441022 0,11145525 ! memory GO:0007613 5 5 0,000 0,03441022 0,11125971 ! dopamine receptor signaling pathway GO:0007212 5 5 0,000 0,03441022 0,11106486 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 5 5 0,000 0,03441022 0,11087069 ! membrane hyperpolarization GO:0060081 5 5 0,000 0,03441022 0,1106772 ! response to lipid GO:0033993 5 5 0,000 0,03441022 0,11048438 ! erythrocyte maturation GO:0043249 5 5 0,000 0,03441022 0,11029224 ! hippocampus development GO:0021766 6 5 0,000 0,03441022 0,11010076 ! regulation of carbohydrate biosynthetic process GO:0043255 5 5 0,000 0,03441022 0,10990994 ! glucocorticoid metabolic process GO:0008211 5 5 0,000 0,03441022 0,10971979 ! middle ear morphogenesis GO:0042474 5 5 0,000 0,03441022 0,10953029 ! amyloid precursor protein catabolic process GO:0042987 5 5 0,000 0,03441022 0,10934144 ! mechanosensory behavior GO:0007638 5 5 0,000 0,03441022 0,10915325 ! heart looping GO:0001947 5 5 0,000 0,03441022 0,1089657 ! negative regulation of endocytosis GO:0045806 5 5 0,000 0,03441022 0,10877879 ! response to interferon-gamma GO:0034341 5 5 0,000 0,03441022 0,10859253 ! pseudouridine synthesis GO:0001522 5 5 0,000 0,03441022 0,1084069 ! endocrine pancreas development GO:0031018 5 5 0,000 0,03441022 0,1082219 ! pH reduction GO:0045851 5 5 0,000 0,03441022 0,10803754 GO:0051452|intracellular pH reduction, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 5 5 0,000 0,03441022 0,1078538 ! lipopolysaccharide metabolic process GO:0008653 5 5 0,000 0,03441022 0,10767069 ! positive regulation of chemokine biosynthetic process GO:0045080 5 5 0,000 0,03441022 0,1074882 ! sphingoid biosynthetic process GO:0046520 5 5 0,000 0,03441022 0,10730632 GO:0046513|ceramide biosynthetic process, ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 5 5 0,000 0,03441022 0,10712506 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! thymic T cell selection GO:0045061 5 5 0,000 0,03441022 0,10694441 ! photoreceptor cell maintenance GO:0045494 5 5 0,000 0,03441022 0,10676437 ! regulation of cardiac muscle hypertrophy GO:0010611 5 5 0,000 0,03441022 0,10658493 GO:0010612|regulation of cardiac muscle adaptation, GO:0014743|regulation of muscle hypertrophy, GO:0043502|regulation of muscle adaptation, ! melanocyte differentiation GO:0030318 5 5 0,000 0,03441022 0,1064061 GO:0050931|pigment cell differentiation, ! ovulation GO:0030728 5 5 0,000 0,03441022 0,10622787 ! mitochondrial respiratory chain complex assembly GO:0033108 5 5 0,000 0,03441022 0,10605023 GO:0032981|mitochondrial respiratory chain complex I assembly, GO:0010257|NADH dehydrogenase complex assembly, ! pituitary gland development GO:0021983 5 5 0,000 0,03441022 0,10587318 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 5 5 0,000 0,03441022 0,10569673 GO:0033135|regulation of peptidyl-serine phosphorylation, ! tyrosine metabolic process GO:0006570 5 5 0,000 0,03441022 0,10552086 ! cytoskeletal anchoring at plasma membrane GO:0007016 6 5 0,000 0,03441022 0,10534557 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 5 5 0,000 0,03441022 0,10517087 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, GO:0009164|nucleoside catabolic process, ! microtubule nucleation GO:0007020 5 5 0,000 0,03441022 0,10499675 ! regulation of interleukin-6 biosynthetic process GO:0045408 5 5 0,000 0,03441022 0,1048232 ! regulation of interleukin-8 biosynthetic process GO:0045414 5 5 0,000 0,03441022 0,10465022 ! indolalkylamine metabolic process GO:0006586 5 5 0,000 0,03441022 0,10447782 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! muscle cell migration GO:0014812 5 5 0,000 0,03441022 0,10430598 ! phasic smooth muscle contraction GO:0014821 5 5 0,000 0,03441022 0,10413471 ! central nervous system neuron axonogenesis GO:0021955 6 5 0,000 0,03441022 0,10396399 GO:0021952|central nervous system projection neuron axonogenesis, ! sister chromatid cohesion GO:0007062 5 5 0,000 0,03441022 0,10379384 ! response to ATP GO:0033198 5 5 0,000 0,03441022 0,10362424 ! regulation of type I interferon production GO:0032479 5 5 0,000 0,03441022 0,1034552 ! regulation of appetite GO:0032098 5 5 0,000 0,03441022 0,1032867 GO:0032095|regulation of response to food, ! vesicle fusion GO:0006906 5 5 0,000 0,03441022 0,10311876 ! paraxial mesoderm development GO:0048339 5 5 0,000 0,03441022 0,10295136 ! regulation of the force of heart contraction GO:0002026 5 5 0,000 0,03441022 0,1027845 ! maintenance of protein location in nucleus GO:0051457 5 5 0,000 0,03441022 0,10261818 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,03441022 0,1024524 ! receptor clustering GO:0043113 5 5 0,000 0,03441022 0,10228715 ! neurotransmitter biosynthetic process GO:0042136 6 5 0,000 0,03441022 0,10212244 ! actin cytoskeleton reorganization GO:0031532 5 5 0,000 0,03441022 0,10195826 ! lens development in camera-type eye GO:0002088 5 5 0,000 0,03441022 0,1017946 ! retinol metabolic process GO:0042572 5 5 0,000 0,03441022 0,10163147 ! corticosteroid receptor signaling pathway GO:0031958 5 5 0,000 0,03441022 0,10146886 GO:0042921|glucocorticoid receptor signaling pathway, ! temperature homeostasis GO:0001659 5 5 0,000 0,03441022 0,10130677 ! positive regulation of exocytosis GO:0045921 6 5 0,000 0,03441022 0,10114519 ! parturition GO:0007567 5 5 0,000 0,03441022 0,10098413 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,03441022 0,10082359 ! regulation of vascular endothelial growth factor production GO:0010574 5 5 0,000 0,03441022 0,10066355 ! acyl-CoA metabolic process GO:0006637 5 5 0,000 0,03441022 0,10050402 ! wound healing, spreading of epidermal cells GO:0035313 5 5 0,000 0,03441022 0,10034499 ! protein heterooligomerization GO:0051291 5 5 0,000 0,03441022 0,10018647 ! positive regulation of peptide secretion GO:0002793 5 5 0,000 0,03441022 0,10002845 ! oligodendrocyte development GO:0014003 5 5 0,000 0,03441022 0,09987092 ! hyaluronan metabolic process GO:0030212 5 5 0,000 0,03441022 0,09971389 ! activated T cell proliferation GO:0050798 5 5 0,000 0,03441022 0,09955736 ! interaction with symbiont GO:0051702 5 5 0,000 0,03441022 0,09940131 ! cellular extravasation GO:0045123 5 5 0,000 0,03441022 0,09924575 ! positive regulation of axonogenesis GO:0050772 5 5 0,000 0,03441022 0,09909068 ! peptidyl-asparagine modification GO:0018196 5 5 0,000 0,03441022 0,09893609 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! positive regulation of phagocytosis GO:0050766 5 5 0,000 0,03441022 0,09878199 ! regulation of insulin receptor signaling pathway GO:0046626 5 5 0,000 0,03441022 0,09862836 ! antigen processing and presentation of exogenous antigen GO:0019884 5 5 0,000 0,03441022 0,09847521 ! enucleate erythrocyte differentiation GO:0043353 6 5 0,000 0,03441022 0,09832254 ! response to amine stimulus GO:0014075 5 5 0,000 0,03441022 0,09817033 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 5 5 0,000 0,03441022 0,0980186 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 5 5 0,000 0,03441022 0,09786734 ! synaptic vesicle exocytosis GO:0016079 6 5 0,000 0,03441022 0,09771654 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 5 5 0,000 0,03441022 0,09756621 ! glycosylceramide metabolic process GO:0006677 5 5 0,000 0,03441022 0,09741634 ! neuron recognition GO:0008038 5 5 0,000 0,03441022 0,09726693 ! negative regulation of focal adhesion formation GO:0051895 6 5 0,000 0,03441022 0,09711797 ! decidualization GO:0046697 5 5 0,000 0,03441022 0,09696947 ! hair follicle maturation GO:0048820 5 5 0,000 0,03441022 0,09682143 ! phosphatidylinositol biosynthetic process GO:0006661 5 5 0,000 0,03441022 0,09667384 ! purine deoxyribonucleotide metabolic process GO:0009151 5 5 0,000 0,03441022 0,09652669 GO:0009155|purine deoxyribonucleotide catabolic process, ! regulation of interleukin-12 production GO:0032655 5 5 0,000 0,03441022 0,09637999 ! positive regulation of interleukin-6 production GO:0032755 5 5 0,000 0,03441022 0,09623374 ! positive regulation of monooxygenase activity GO:0032770 5 5 0,000 0,03441022 0,09608793 ! postreplication repair GO:0006301 5 5 0,000 0,03441022 0,09594257 ! spinal cord motor neuron differentiation GO:0021522 5 5 0,000 0,03441022 0,09579764 GO:0021517|ventral spinal cord development, ! histone methylation GO:0016571 5 5 0,000 0,03441022 0,09565315 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,03441022 0,09550909 ! positive regulation of immunoglobulin mediated immune response GO:0002891 5 5 0,000 0,03441022 0,09536547 GO:0002714|positive regulation of B cell mediated immunity, ! positive regulation of interferon-gamma production GO:0032729 5 5 0,000 0,03441022 0,09522228 ! negative regulation of tumor necrosis factor production GO:0032720 5 5 0,000 0,03441022 0,09507951 ! intracellular cholesterol transport GO:0032367 5 5 0,000 0,03441022 0,09493718 GO:0032366|intracellular sterol transport, ! regulation of mast cell activation GO:0033003 5 5 0,000 0,03441022 0,09479527 ! morphogenesis of a polarized epithelium GO:0001738 5 5 0,000 0,03441022 0,09465379 ! regulation of hormone metabolic process GO:0032350 5 5 0,000 0,03441022 0,09451272 ! regulation of transcription from RNA polymerase III promoter GO:0006359 5 5 0,000 0,03441022 0,09437208 ! regulation of inflammatory response to antigenic stimulus GO:0002861 5 5 0,000 0,03441022 0,09423185 ! sterol catabolic process GO:0016127 5 5 0,000 0,03441022 0,09409204 GO:0006707|cholesterol catabolic process, ! negative regulation of oxidoreductase activity GO:0051354 5 5 0,000 0,03441022 0,09395265 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 5 5 0,000 0,03441022 0,09381366 ! detection of biotic stimulus GO:0009595 5 5 0,000 0,03441022 0,09367509 ! regulation of immune response to tumor cell GO:0002837 5 5 0,000 0,03441022 0,09353693 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of DNA replication initiation GO:0030174 5 5 0,000 0,03441022 0,09339917 ! zymogen activation GO:0031638 5 5 0,000 0,03441022 0,09326182 ! positive regulation of interleukin-1 beta secretion GO:0050718 5 5 0,000 0,03441022 0,09312487 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 5 5 0,000 0,03441022 0,09298832 GO:0002820|negative regulation of adaptive immune response, ! cellular response to nutrient GO:0031670 5 5 0,000 0,03441022 0,09285218 ! peptidyl-histidine modification GO:0018202 5 5 0,000 0,03441022 0,09271643 ! nucleosome positioning GO:0016584 5 5 0,000 0,03441022 0,09258107 ! regulation of isotype switching GO:0045191 5 5 0,000 0,03441022 0,09244612 ! negative regulation of neurological system process GO:0031645 5 5 0,000 0,03441022 0,09231155 ! regulation of myoblast differentiation GO:0045661 5 5 0,000 0,03441022 0,09217738 ! glutathione biosynthetic process GO:0006750 5 5 0,000 0,03441022 0,09204359 ! NADPH regeneration GO:0006740 5 5 0,000 0,03441022 0,0919102 GO:0006098|pentose-phosphate shunt, ! positive regulation of erythrocyte differentiation GO:0045648 5 5 0,000 0,03441022 0,09177719 ! positive regulation of epidermis development GO:0045684 5 5 0,000 0,03441022 0,09164456 ! positive regulation of leukocyte chemotaxis GO:0002690 5 5 0,000 0,03441022 0,09151232 GO:0002688|regulation of leukocyte chemotaxis, ! musculoskeletal movement GO:0050881 5 5 0,000 0,03441022 0,09138046 GO:0050879|multicellular organismal movement, ! neuromuscular process controlling posture GO:0050884 5 5 0,000 0,03441022 0,09124897 ! sarcomere organization GO:0045214 5 5 0,000 0,03441022 0,09111787 ! regulation of epidermal cell differentiation GO:0045604 5 5 0,000 0,03441022 0,09098714 ! activation of NF-kappaB-inducing kinase activity GO:0007250 5 5 0,000 0,03441022 0,09085679 ! negative regulation of glucose transport GO:0010829 5 5 0,000 0,03441022 0,0907268 GO:0046325|negative regulation of glucose import, ! positive regulation of T-helper cell differentiation GO:0045624 5 5 0,000 0,03441022 0,09059719 GO:0045622|regulation of T-helper cell differentiation, ! dopamine biosynthetic process GO:0042416 5 5 0,000 0,03441022 0,09046795 ! male genitalia development GO:0030539 5 5 0,000 0,03441022 0,09033908 ! nicotinamide nucleotide biosynthetic process GO:0019359 5 5 0,000 0,03441022 0,09021058 ! quaternary ammonium group transport GO:0015697 5 5 0,000 0,03441022 0,09008244 ! thyroid hormone metabolic process GO:0042403 5 5 0,000 0,03441022 0,08995466 ! leukocyte mediated cytotoxicity GO:0001909 5 5 0,000 0,03441022 0,08982725 ! positive regulation of viral reproduction GO:0048524 5 5 0,000 0,03441022 0,08970019 ! removal of superoxide radicals GO:0019430 6 5 0,000 0,03441022 0,0895735 ! myeloid cell homeostasis GO:0002262 5 5 0,000 0,03441022 0,08944716 ! regulation of fatty acid oxidation GO:0046320 5 5 0,000 0,03441022 0,08932118 ! ATP catabolic process GO:0006200 5 5 0,000 0,03441022 0,08919555 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,03441022 0,08907028 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 5 5 0,000 0,03441022 0,08894535 ! blastocyst formation GO:0001825 5 5 0,000 0,03441022 0,08882078 ! regulation of fibrinolysis GO:0051917 5 5 0,000 0,03441022 0,08869655 ! embryonic gut development GO:0048566 5 5 0,000 0,03441022 0,08857268 ! negative regulation of organic acid transport GO:0032891 5 5 0,000 0,03441022 0,08844914 ! pyrimidine base metabolic process GO:0006206 5 5 0,000 0,03441022 0,08832596 ! activation of innate immune response GO:0002218 5 5 0,000 0,03441022 0,08820311 GO:0002758|innate immune response-activating signal transduction, ! positive regulation of blood vessel endothelial cell migration GO:0043536 5 5 0,000 0,03441022 0,08808061 ! catecholamine transport GO:0051937 5 5 0,000 0,03441022 0,08795844 ! negative regulation of blood vessel endothelial cell migration GO:0043537 5 5 0,000 0,03441022 0,08783661 ! regulation of NF-kappaB import into nucleus GO:0042345 5 5 0,000 0,03441022 0,08771513 ! muscle adaptation GO:0043500 5 5 0,000 0,03441022 0,08759397 ! positive regulation of actin filament bundle formation GO:0032233 5 5 0,000 0,03441022 0,08747315 ! embryonic heart tube development GO:0035050 5 5 0,000 0,03441022 0,08735267 ! cardiac cell differentiation GO:0035051 6 5 0,000 0,03441022 0,08723251 ! positive regulation of homeostatic process GO:0032846 5 5 0,000 0,03441022 0,08711269 ! defense response to fungus GO:0050832 5 5 0,000 0,03441022 0,08699319 ! lysogeny GO:0030069 5 5 0,000 0,03441022 0,08687402 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 5 5 0,000 0,03441022 0,08675518 ! B cell receptor signaling pathway GO:0050853 5 5 0,000 0,03441022 0,08663666 ! positive regulation of smooth muscle contraction GO:0045987 5 5 0,000 0,03441022 0,08651847 ! establishment of cell polarity GO:0030010 5 5 0,000 0,03441022 0,08640059 ! mitochondrion localization GO:0051646 5 5 0,000 0,03441022 0,08628304 ! nucleus localization GO:0051647 5 5 0,000 0,03441022 0,08616581 ! regulation of synapse structure and activity GO:0050803 5 5 0,000 0,03441022 0,0860489 ! alcohol catabolic process GO:0046164 43 43 1,000 0,03589876 0,08964962 ! regulation of nucleotide metabolic process GO:0006140 43 43 1,000 0,03589876 0,08952831 ! humoral immune response GO:0006959 44 44 1,000 0,03744375 0,09325518 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 45 44 1,000 0,03744375 0,09312933 ! protein import into nucleus GO:0006606 44 44 1,000 0,03744375 0,09300382 ! negative regulation of organelle organization GO:0010639 45 44 1,000 0,03744375 0,09287864 ! positive regulation of lymphocyte activation GO:0051251 44 44 1,000 0,03744375 0,09275381 ! homophilic cell adhesion GO:0007156 45 45 1,000 0,03901403 0,0965139 ! regulation of DNA binding GO:0051101 47 45 1,000 0,03901403 0,09638453 ! phosphoinositide-mediated signaling GO:0048015 45 45 1,000 0,03901403 0,0962555 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 46 45 1,000 0,03901403 0,09612682 ! nuclear import GO:0051170 45 45 1,000 0,03901403 0,09599848 ! regulation of peptidase activity GO:0052547 46 46 1,000 0,04060919 0,09979032 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 47 46 1,000 0,04060919 0,09965744 ! positive regulation of ligase activity GO:0051351 47 46 1,000 0,04060919 0,09952492 ! axon extension GO:0048675 7 6 0,000 0,04115179 0,10072079 ! oligosaccharide biosynthetic process GO:0009312 6 6 0,000 0,04115179 0,10058721 ! somatic diversification of immune receptors via somatic mutation GO:0002566 6 6 0,000 0,04115179 0,10045398 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 6 6 0,000 0,04115179 0,1003211 ! negative regulation of cellular catabolic process GO:0031330 6 6 0,000 0,04115179 0,10018858 ! virus-host interaction GO:0019048 6 6 0,000 0,04115179 0,1000564 ! regulation of S phase GO:0033261 6 6 0,000 0,04115179 0,09992458 ! myotube differentiation GO:0014902 6 6 0,000 0,04115179 0,0997931 ! bone remodeling GO:0046849 6 6 0,000 0,04115179 0,09966196 ! N-glycan processing GO:0006491 6 6 0,000 0,04115179 0,09953117 ! regulation of lipid kinase activity GO:0043550 6 6 0,000 0,04115179 0,09940073 ! glycosaminoglycan catabolic process GO:0006027 6 6 0,000 0,04115179 0,09927062 ! negative regulation of JAK-STAT cascade GO:0046426 6 6 0,000 0,04115179 0,09914085 ! retina development in camera-type eye GO:0060041 6 6 0,000 0,04115179 0,09901143 ! RNA methylation GO:0001510 6 6 0,000 0,04115179 0,09888234 ! cartilage condensation GO:0001502 7 6 0,000 0,04115179 0,09875359 ! regulation of positive chemotaxis GO:0050926 6 6 0,000 0,04115179 0,09862517 GO:0050927|positive regulation of positive chemotaxis, ! positive regulation of neurotransmitter transport GO:0051590 6 6 0,000 0,04115179 0,09849708 ! bile acid metabolic process GO:0008206 6 6 0,000 0,04115179 0,09836933 ! androgen metabolic process GO:0008209 6 6 0,000 0,04115179 0,09824191 ! estrogen metabolic process GO:0008210 6 6 0,000 0,04115179 0,09811482 ! limbic system development GO:0021761 7 6 0,000 0,04115179 0,09798805 ! cytoplasmic sequestering of transcription factor GO:0042994 6 6 0,000 0,04115179 0,09786162 ! positive regulation of heart contraction GO:0045823 6 6 0,000 0,04115179 0,09773551 ! positive regulation of gene expression, epigenetic GO:0045815 6 6 0,000 0,04115179 0,09760972 ! pathogenesis GO:0009405 6 6 0,000 0,04115179 0,09748426 ! negative regulation of protein amino acid phosphorylation GO:0001933 6 6 0,000 0,04115179 0,09735912 ! positive regulation of cell growth GO:0030307 6 6 0,000 0,04115179 0,0972343 ! ribonucleoside triphosphate catabolic process GO:0009203 6 6 0,000 0,04115179 0,0971098 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! regulation of chemokine biosynthetic process GO:0045073 6 6 0,000 0,04115179 0,09698562 ! nerve growth factor receptor signaling pathway GO:0048011 6 6 0,000 0,04115179 0,09686175 ! inositol phosphate-mediated signaling GO:0048016 6 6 0,000 0,04115179 0,09673821 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 6 6 0,000 0,04115179 0,09661497 ! arginine metabolic process GO:0006525 6 6 0,000 0,04115179 0,09649205 GO:0006527|arginine catabolic process, ! regulation of catecholamine secretion GO:0050433 6 6 0,000 0,04115179 0,09636945 ! oligodendrocyte differentiation GO:0048709 6 6 0,000 0,04115179 0,09624715 ! glutamate catabolic process GO:0006538 7 6 0,000 0,04115179 0,09612516 ! telomere maintenance via telomerase GO:0007004 6 6 0,000 0,04115179 0,09600349 GO:0010833|telomere maintenance via telomere lengthening, ! L-phenylalanine metabolic process GO:0006558 6 6 0,000 0,04115179 0,09588212 GO:0006559|L-phenylalanine catabolic process, ! glucan biosynthetic process GO:0009250 6 6 0,000 0,04115179 0,09576105 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 6 6 0,000 0,04115179 0,09564029 ! V(D)J recombination GO:0033151 6 6 0,000 0,04115179 0,09551984 ! vascular smooth muscle contraction GO:0014829 6 6 0,000 0,04115179 0,09539969 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 6 6 0,000 0,04115179 0,09527984 ! negative regulation of endothelial cell migration GO:0010596 6 6 0,000 0,04115179 0,09516029 ! regulation of heart rate GO:0002027 6 6 0,000 0,04115179 0,09504104 ! lipid digestion GO:0044241 6 6 0,000 0,04115179 0,09492209 ! retrograde transport, endosome to Golgi GO:0042147 6 6 0,000 0,04115179 0,09480344 ! phagocytosis, engulfment GO:0006911 6 6 0,000 0,04115179 0,09468509 ! regulation of vascular permeability GO:0043114 6 6 0,000 0,04115179 0,09456702 ! regulation of calcium ion transport into cytosol GO:0010522 6 6 0,000 0,04115179 0,09444926 ! ruffle organization GO:0031529 6 6 0,000 0,04115179 0,09433178 ! preassembly of GPI anchor in ER membrane GO:0016254 6 6 0,000 0,04115179 0,0942146 ! retinoic acid metabolic process GO:0042573 6 6 0,000 0,04115179 0,09409771 ! neutral amino acid transport GO:0015804 6 6 0,000 0,04115179 0,09398111 ! L-amino acid transport GO:0015807 6 6 0,000 0,04115179 0,09386479 ! bone mineralization GO:0030282 6 6 0,000 0,04115179 0,09374877 GO:0031214|biomineral formation, ! rRNA modification GO:0000154 6 6 0,000 0,04115179 0,09363303 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 6 6 0,000 0,04115179 0,09351758 GO:0002717|positive regulation of natural killer cell mediated immunity, GO:0002715|regulation of natural killer cell mediated immunity, GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 7 6 0,000 0,04115179 0,09340241 ! purine base biosynthetic process GO:0009113 6 6 0,000 0,04115179 0,09328752 ! G1 DNA damage checkpoint GO:0031571 6 6 0,000 0,04115179 0,09317292 ! negative regulation of axonogenesis GO:0050771 7 6 0,000 0,04115179 0,09305859 ! regulation of phagocytosis GO:0050764 6 6 0,000 0,04115179 0,09294455 ! regulation of organ growth GO:0046620 6 6 0,000 0,04115179 0,09283079 ! regulation of circadian rhythm GO:0042752 6 6 0,000 0,04115179 0,0927173 ! positive regulation of T cell mediated immunity GO:0002711 6 6 0,000 0,04115179 0,09260409 ! response to dsRNA GO:0043331 6 6 0,000 0,04115179 0,09249116 ! DNA unwinding during replication GO:0006268 6 6 0,000 0,04115179 0,09237851 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 6 6 0,000 0,04115179 0,09226612 GO:0009147|pyrimidine nucleoside triphosphate metabolic process, ! genitalia development GO:0048806 6 6 0,000 0,04115179 0,09215401 ! sphingomyelin metabolic process GO:0006684 6 6 0,000 0,04115179 0,09204218 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 6 6 0,000 0,04115179 0,09193061 ! multicellular organismal aging GO:0010259 6 6 0,000 0,04115179 0,09181931 ! regulation of focal adhesion formation GO:0051893 7 6 0,000 0,04115179 0,09170829 ! respiratory chain complex IV assembly GO:0008535 6 6 0,000 0,04115179 0,09159753 ! erythrocyte development GO:0048821 6 6 0,000 0,04115179 0,09148704 ! renal water homeostasis GO:0003091 6 6 0,000 0,04115179 0,09137681 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 6 6 0,000 0,04115179 0,09126685 GO:0043372|positive regulation of CD4-positive, alpha beta T cell differentiation, ! ribosomal large subunit biogenesis GO:0042273 6 6 0,000 0,04115179 0,09115716 ! regulation of Rho GTPase activity GO:0032319 6 6 0,000 0,04115179 0,09104772 ! ribosome assembly GO:0042255 6 6 0,000 0,04115179 0,09093855 ! diencephalon development GO:0021536 6 6 0,000 0,04115179 0,09082965 ! fucose catabolic process GO:0019317 6 6 0,000 0,04115179 0,090721 GO:0042355|L-fucose catabolic process, ! nitric oxide metabolic process GO:0046209 6 6 0,000 0,04115179 0,09061261 GO:0006809|nitric oxide biosynthetic process, ! protein sumoylation GO:0016925 6 6 0,000 0,04115179 0,09050448 ! regulation of lipid transport GO:0032368 6 6 0,000 0,04115179 0,09039661 ! regulation of cell division GO:0051302 6 6 0,000 0,04115179 0,09028899 ! positive regulation of interleukin-1 secretion GO:0050716 6 6 0,000 0,04115179 0,09018163 ! cellular metabolic compound salvage GO:0043094 6 6 0,000 0,04115179 0,09007453 ! regulation of T-helper 2 type immune response GO:0002828 6 6 0,000 0,04115179 0,08996768 ! salivary gland morphogenesis GO:0007435 6 6 0,000 0,04115179 0,08986108 ! neuroblast proliferation GO:0007405 6 6 0,000 0,04115179 0,08975474 ! regulation of interleukin-1 beta secretion GO:0050706 6 6 0,000 0,04115179 0,08964865 ! nitric oxide mediated signal transduction GO:0007263 6 6 0,000 0,04115179 0,0895428 ! regulation of glucose transport GO:0010827 6 6 0,000 0,04115179 0,08943721 GO:0046324|regulation of glucose import, ! intestinal absorption GO:0050892 6 6 0,000 0,04115179 0,08933187 ! methionine biosynthetic process GO:0009086 6 6 0,000 0,04115179 0,08922677 ! glutamine family amino acid biosynthetic process GO:0009084 6 6 0,000 0,04115179 0,08912192 ! serine family amino acid biosynthetic process GO:0009070 6 6 0,000 0,04115179 0,08901732 ! lymph node development GO:0048535 6 6 0,000 0,04115179 0,08891296 ! organic cation transport GO:0015695 6 6 0,000 0,04115179 0,08880885 ! negative regulation of BMP signaling pathway GO:0030514 6 6 0,000 0,04115179 0,08870498 ! regulation of RNA splicing GO:0043484 6 6 0,000 0,04115179 0,08860135 ! regulation of cellular carbohydrate catabolic process GO:0043471 6 6 0,000 0,04115179 0,08849796 GO:0043470|regulation of carbohydrate catabolic process, GO:0006110|regulation of glycolysis, ! positive regulation of JNK cascade GO:0046330 7 6 0,000 0,04115179 0,08839482 ! sperm-egg recognition GO:0035036 7 6 0,000 0,04115179 0,08829191 GO:0007339|binding of sperm to zona pellucida, ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 6 6 0,000 0,04115179 0,08818925 ! alditol metabolic process GO:0019400 6 6 0,000 0,04115179 0,08808682 ! regulation of amino acid transport GO:0051955 6 6 0,000 0,04115179 0,08798463 ! maternal placenta development GO:0001893 6 6 0,000 0,04115179 0,08788268 ! regulation of embryonic development GO:0045995 6 6 0,000 0,04115179 0,08778096 ! negative regulation of immune effector process GO:0002698 6 6 0,000 0,04115179 0,08767948 ! regulation of ubiquitin-protein ligase activity GO:0051438 49 48 1,000 0,04387252 0,09336843 ! regulation of cell cycle process GO:0010564 50 48 1,000 0,04387252 0,09326074 ! protein localization in nucleus GO:0034504 48 48 1,000 0,04387252 0,09315329 ! cell cycle arrest GO:0007050 49 49 1,000 0,04553989 0,09658231 ! response to nutrient GO:0007584 49 49 1,000 0,04553989 0,09647129 ! regulation of ligase activity GO:0051340 50 49 1,000 0,04553989 0,09636053 ! positive regulation of cell activation GO:0050867 49 49 1,000 0,04553989 0,09625003 GO:0002696|positive regulation of leukocyte activation, ! regulation of defense response GO:0031347 50 50 1,000 0,04723054 0,09970892 ! negative regulation of transport GO:0051051 51 50 1,000 0,04723054 0,09959483 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 50 50 1,000 0,04723054 0,09948101 ! anatomical structure homeostasis GO:0060249 51 50 1,000 0,04723054 0,09936745 ! anterior/posterior pattern formation GO:0009952 51 50 1,000 0,04723054 0,09925414 ! respiratory burst GO:0045730 7 7 0,000 0,04784727 0,10043567 ! negative regulation of cell projection organization GO:0031345 8 7 0,000 0,04784727 0,10032141 ! positive regulation of blood pressure GO:0045777 7 7 0,000 0,04784727 0,10020741 ! positive regulation of cellular catabolic process GO:0031331 7 7 0,000 0,04784727 0,10009367 ! pteridine and derivative biosynthetic process GO:0042559 7 7 0,000 0,04784727 0,09998018 ! regulation of chemokine production GO:0032642 7 7 0,000 0,04784727 0,09986695 ! double-strand break repair via homologous recombination GO:0000724 7 7 0,000 0,04784727 0,09975398 GO:0000725|recombinational repair, ! SMAD protein nuclear translocation GO:0007184 7 7 0,000 0,04784727 0,09964126 ! cellular protein complex disassembly GO:0043624 8 7 0,000 0,04784727 0,0995288 GO:0043241|protein complex disassembly, ! gene silencing by RNA GO:0031047 7 7 0,000 0,04784727 0,09941659 ! regulation of receptor-mediated endocytosis GO:0048259 7 7 0,000 0,04784727 0,09930464 ! regulation of neurotransmitter transport GO:0051588 7 7 0,000 0,04784727 0,09919293 ! keratinocyte proliferation GO:0043616 7 7 0,000 0,04784727 0,09908148 ! axis specification GO:0009798 7 7 0,000 0,04784727 0,09897028 ! negative regulation of muscle cell differentiation GO:0051148 7 7 0,000 0,04784727 0,09885933 ! startle response GO:0001964 7 7 0,000 0,04784727 0,09874862 ! amyloid precursor protein metabolic process GO:0042982 7 7 0,000 0,04784727 0,09863816 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 8 7 0,000 0,04784727 0,09852795 ! positive regulation of lipid metabolic process GO:0045834 7 7 0,000 0,04784727 0,09841799 ! negative regulation of lipid metabolic process GO:0045833 7 7 0,000 0,04784727 0,09830827 ! regulation of interferon-gamma biosynthetic process GO:0045072 7 7 0,000 0,04784727 0,0981988 ! endothelial cell differentiation GO:0045446 7 7 0,000 0,04784727 0,09808957 ! negative regulation of striated muscle development GO:0045843 7 7 0,000 0,04784727 0,09798058 ! hemoglobin metabolic process GO:0020027 7 7 0,000 0,04784727 0,09787183 ! regulation of exit from mitosis GO:0007096 7 7 0,000 0,04784727 0,09776332 ! protein targeting to ER GO:0045047 8 7 0,000 0,04784727 0,09765506 ! cell differentiation in spinal cord GO:0021515 7 7 0,000 0,04784727 0,09754703 ! endoderm development GO:0007492 7 7 0,000 0,04784727 0,09743925 ! regulation of defense response to virus GO:0050688 7 7 0,000 0,04784727 0,0973317 ! glycolipid biosynthetic process GO:0009247 7 7 0,000 0,04784727 0,09722439 GO:0006688|glycosphingolipid biosynthetic process, ! regulation of mRNA processing GO:0050684 7 7 0,000 0,04784727 0,09711731 ! response to hexose stimulus GO:0009746 7 7 0,000 0,04784727 0,09701047 GO:0034284|response to monosaccharide stimulus, GO:0009749|response to glucose stimulus, ! membrane protein ectodomain proteolysis GO:0006509 7 7 0,000 0,04784727 0,09690387 GO:0033619|membrane protein proteolysis, ! cardiac muscle tissue development GO:0048738 7 7 0,000 0,04784727 0,0967975 ! nucleotide-sugar metabolic process GO:0009225 7 7 0,000 0,04784727 0,09669136 ! complement activation, alternative pathway GO:0006957 7 7 0,000 0,04784727 0,09658545 ! arachidonic acid secretion GO:0050482 7 7 0,000 0,04784727 0,09647978 GO:0032309|icosanoid secretion, ! polyamine biosynthetic process GO:0006596 7 7 0,000 0,04784727 0,09637434 ! response to X-ray GO:0010165 7 7 0,000 0,04784727 0,09626913 ! regulation of intracellular pH GO:0051453 7 7 0,000 0,04784727 0,09616414 ! UV protection GO:0009650 7 7 0,000 0,04784727 0,09605939 ! DNA integration GO:0015074 7 7 0,000 0,04784727 0,09595486 ! myofibril assembly GO:0030239 7 7 0,000 0,04784727 0,09585056 GO:0055002|striated muscle cell development, ! positive regulation of carbohydrate metabolic process GO:0045913 7 7 0,000 0,04784727 0,09574649 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! positive regulation of muscle contraction GO:0045933 7 7 0,000 0,04784727 0,09564265 ! negative regulation of muscle contraction GO:0045932 7 7 0,000 0,04784727 0,09553902 ! chondroitin sulfate biosynthetic process GO:0030206 7 7 0,000 0,04784727 0,09543563 GO:0030204|chondroitin sulfate metabolic process, ! regulation of exocytosis GO:0017157 8 7 0,000 0,04784727 0,09533245 ! phosphatidylcholine biosynthetic process GO:0006656 7 7 0,000 0,04784727 0,0952295 ! heparan sulfate proteoglycan metabolic process GO:0030201 7 7 0,000 0,04784727 0,09512677 GO:0015012|heparan sulfate proteoglycan biosynthetic process, ! stem cell development GO:0048864 7 7 0,000 0,04784727 0,09502427 GO:0019827|stem cell maintenance, ! negative regulation of myeloid leukocyte differentiation GO:0002762 7 7 0,000 0,04784727 0,09492198 ! axon cargo transport GO:0008088 7 7 0,000 0,04784727 0,09481991 ! eating behavior GO:0042755 7 7 0,000 0,04784727 0,09471807 ! RNA-dependent DNA replication GO:0006278 7 7 0,000 0,04784727 0,09461644 ! purine nucleoside triphosphate catabolic process GO:0009146 7 7 0,000 0,04784727 0,09451503 ! regulation of interleukin-8 production GO:0032677 7 7 0,000 0,04784727 0,09441383 ! purine ribonucleotide catabolic process GO:0009154 7 7 0,000 0,04784727 0,09431285 ! ribosomal small subunit biogenesis GO:0042274 7 7 0,000 0,04784727 0,09421209 ! cranial nerve development GO:0021545 7 7 0,000 0,04784727 0,09411155 ! protein import into peroxisome matrix GO:0016558 7 7 0,000 0,04784727 0,09401121 ! induction of an organ GO:0001759 7 7 0,000 0,04784727 0,0939111 ! leukocyte activation during immune response GO:0002366 7 7 0,000 0,04784727 0,09381119 GO:0002263|cell activation during immune response, ! response to estradiol stimulus GO:0032355 7 7 0,000 0,04784727 0,0937115 ! intracellular lipid transport GO:0032365 7 7 0,000 0,04784727 0,09361202 ! detection of chemical stimulus GO:0009593 8 7 0,000 0,04784727 0,09351275 ! platelet activation GO:0030168 8 7 0,000 0,04784727 0,09341369 ! negative regulation of cytokine secretion GO:0050710 7 7 0,000 0,04784727 0,09331484 ! regulation of interleukin-1 secretion GO:0050704 7 7 0,000 0,04784727 0,09321619 ! NADP metabolic process GO:0006739 7 7 0,000 0,04784727 0,09311776 ! neuromuscular synaptic transmission GO:0007274 7 7 0,000 0,04784727 0,09301953 ! synaptic transmission, cholinergic GO:0007271 7 7 0,000 0,04784727 0,09292152 ! ubiquinone metabolic process GO:0006743 7 7 0,000 0,04784727 0,0928237 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, GO:0042375|quinone cofactor metabolic process, ! regulation of macrophage differentiation GO:0045649 8 7 0,000 0,04784727 0,0927261 ! positive regulation of acute inflammatory response GO:0002675 7 7 0,000 0,04784727 0,0926287 ! regulation of osteoclast differentiation GO:0045670 7 7 0,000 0,04784727 0,0925315 ! negative regulation of cell-substrate adhesion GO:0010812 8 7 0,000 0,04784727 0,09243451 GO:0001953|negative regulation of cell-matrix adhesion, ! multicellular organismal water homeostasis GO:0050891 7 7 0,000 0,04784727 0,09233772 ! regulation of ATPase activity GO:0043462 7 7 0,000 0,04784727 0,09224113 ! cell-cell recognition GO:0009988 8 7 0,000 0,04784727 0,09214474 ! hormone catabolic process GO:0042447 7 7 0,000 0,04784727 0,09204856 ! dopamine metabolic process GO:0042417 7 7 0,000 0,04784727 0,09195257 ! cAMP biosynthetic process GO:0006171 7 7 0,000 0,04784727 0,09185679 ! oxygen transport GO:0015671 7 7 0,000 0,04784727 0,09176121 ! pyridine nucleotide biosynthetic process GO:0019363 7 7 0,000 0,04784727 0,09166582 ! regulation of mRNA stability GO:0043488 7 7 0,000 0,04784727 0,09157063 ! biogenic amine catabolic process GO:0042402 7 7 0,000 0,04784727 0,09147564 ! regulation of axon extension GO:0030516 7 7 0,000 0,04784727 0,09138085 ! cell killing GO:0001906 7 7 0,000 0,04784727 0,09128625 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 7 7 0,000 0,04784727 0,09119185 ! adult feeding behavior GO:0008343 7 7 0,000 0,04784727 0,09109764 ! pyrimidine nucleotide catabolic process GO:0006244 7 7 0,000 0,04784727 0,09100363 ! positive regulation of protein polymerization GO:0032273 7 7 0,000 0,04784727 0,09090981 ! T cell receptor signaling pathway GO:0050852 7 7 0,000 0,04784727 0,09081619 ! response to cold GO:0009409 7 7 0,000 0,04784727 0,09072276 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 52 52 1,000 0,0506801 0,09599529 ! regulation of GTPase activity GO:0043087 53 52 1,000 0,0506801 0,09589673 ! carbohydrate catabolic process GO:0016052 53 53 1,000 0,05243824 0,09912172 ! tRNA metabolic process GO:0006399 53 53 1,000 0,05243824 0,09902016 ! protein amino acid dephosphorylation GO:0006470 55 54 1,000 0,05421812 0,10227634 ! negative regulation of multicellular organismal process GO:0051241 55 54 1,000 0,05421812 0,10217177 ! negative regulation of muscle development GO:0048635 8 8 0,000 0,05449696 0,10259234 ! very-long-chain fatty acid metabolic process GO:0000038 8 8 0,000 0,05449696 0,10248765 ! positive regulation of translation GO:0045727 8 8 0,000 0,05449696 0,10238318 ! positive regulation of cell killing GO:0031343 8 8 0,000 0,05449696 0,10227892 ! superoxide anion generation GO:0042554 8 8 0,000 0,05449696 0,10217487 ! sulfur amino acid biosynthetic process GO:0000097 8 8 0,000 0,05449696 0,10207104 ! cGMP metabolic process GO:0046068 8 8 0,000 0,05449696 0,10196741 GO:0006182|cGMP biosynthetic process, ! thyroid gland development GO:0030878 8 8 0,000 0,05449696 0,101864 ! dicarboxylic acid transport GO:0006835 8 8 0,000 0,05449696 0,10176079 ! phosphoinositide phosphorylation GO:0046854 8 8 0,000 0,05449696 0,10165779 ! embryonic hindlimb morphogenesis GO:0035116 8 8 0,000 0,05449696 0,10155501 ! zinc ion transport GO:0006829 8 8 0,000 0,05449696 0,10145243 ! embryonic forelimb morphogenesis GO:0035115 8 8 0,000 0,05449696 0,10135005 ! folic acid and derivative biosynthetic process GO:0009396 8 8 0,000 0,05449696 0,10124788 ! cardiac muscle contraction GO:0060048 8 8 0,000 0,05449696 0,10114592 ! response to pain GO:0048265 8 8 0,000 0,05449696 0,10104417 ! response to cAMP GO:0051591 8 8 0,000 0,05449696 0,10094261 ! COPI coating of Golgi vesicle GO:0048205 8 8 0,000 0,05449696 0,10084127 GO:0048200|Golgi transport vesicle coating, ! regulation of excitatory postsynaptic membrane potential GO:0060079 8 8 0,000 0,05449696 0,10074012 ! negative regulation of ion transport GO:0043271 8 8 0,000 0,05449696 0,10063918 ! regulation of response to extracellular stimulus GO:0032104 8 8 0,000 0,05449696 0,10053844 GO:0032107|regulation of response to nutrient levels, ! adult walking behavior GO:0007628 8 8 0,000 0,05449696 0,1004379 ! sensory perception of taste GO:0050909 8 8 0,000 0,05449696 0,10033756 ! organelle fusion GO:0048284 8 8 0,000 0,05449696 0,10023743 ! pancreas development GO:0031016 8 8 0,000 0,05449696 0,10013749 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 8 0,000 0,05449696 0,10003775 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 8 8 0,000 0,05449696 0,09993821 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 8 8 0,000 0,05449696 0,09983887 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 8 8 0,000 0,05449696 0,09973972 ! sperm motility GO:0030317 8 8 0,000 0,05449696 0,09964077 ! regulation of striated muscle contraction GO:0006942 8 8 0,000 0,05449696 0,09954202 ! DNA duplex unwinding GO:0032508 8 8 0,000 0,05449696 0,09944347 GO:0032392|DNA geometric change, ! glycine metabolic process GO:0006544 8 8 0,000 0,05449696 0,0993451 ! ribonucleotide catabolic process GO:0009261 8 8 0,000 0,05449696 0,09924694 ! negative regulation of microtubule depolymerization GO:0007026 8 8 0,000 0,05449696 0,09914896 GO:0031114|regulation of microtubule depolymerization, ! polyamine metabolic process GO:0006595 8 8 0,000 0,05449696 0,09905118 ! Golgi organization GO:0007030 8 8 0,000 0,05449696 0,0989536 ! cell-cell junction assembly GO:0007043 8 8 0,000 0,05449696 0,0988562 ! regulation of stress fiber formation GO:0051492 9 8 0,000 0,05449696 0,098759 ! positive regulation of endothelial cell migration GO:0010595 8 8 0,000 0,05449696 0,09866199 ! mannose metabolic process GO:0006013 9 8 0,000 0,05449696 0,09856516 ! NAD metabolic process GO:0019674 8 8 0,000 0,05449696 0,09846853 ! sex determination GO:0007530 8 8 0,000 0,05449696 0,09837209 ! plasma membrane fusion GO:0045026 8 8 0,000 0,05449696 0,09827583 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 8 8 0,000 0,05449696 0,09817977 ! response to fungus GO:0009620 8 8 0,000 0,05449696 0,09808389 ! stem cell differentiation GO:0048863 8 8 0,000 0,05449696 0,0979882 ! positive regulation of myeloid leukocyte differentiation GO:0002763 9 8 0,000 0,05449696 0,09789269 ! embryonic digit morphogenesis GO:0042733 8 8 0,000 0,05449696 0,09779737 ! regulation of cytokine production during immune response GO:0002718 8 8 0,000 0,05449696 0,09770224 ! base-excision repair, AP site formation GO:0006285 8 8 0,000 0,05449696 0,09760729 ! regulation of vasodilation GO:0042312 8 8 0,000 0,05449696 0,09751253 ! vasoconstriction GO:0042310 8 8 0,000 0,05449696 0,09741794 ! regulation of T cell mediated immunity GO:0002709 8 8 0,000 0,05449696 0,09732355 ! muscle cell development GO:0055001 8 8 0,000 0,05449696 0,09722933 ! nucleoside triphosphate catabolic process GO:0009143 8 8 0,000 0,05449696 0,0971353 ! regulation of fatty acid metabolic process GO:0019217 8 8 0,000 0,05449696 0,09704145 ! sensory perception of pain GO:0019233 8 8 0,000 0,05449696 0,09694778 ! gastrulation with mouth forming second GO:0001702 8 8 0,000 0,05449696 0,09685429 ! immunoglobulin production during immune response GO:0002381 8 8 0,000 0,05449696 0,09676098 GO:0002208|somatic diversification of immunoglobulins during immune response, GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! mRNA cleavage GO:0006379 8 8 0,000 0,05449696 0,09666785 ! chromatin silencing GO:0006342 8 8 0,000 0,05449696 0,0965749 ! tissue regeneration GO:0042246 8 8 0,000 0,05449696 0,09648213 ! salivary gland development GO:0007431 8 8 0,000 0,05449696 0,09638954 ! negative regulation of blood coagulation GO:0030195 9 8 0,000 0,05449696 0,09629712 ! peptide biosynthetic process GO:0043043 9 8 0,000 0,05449696 0,09620489 ! water homeostasis GO:0030104 8 8 0,000 0,05449696 0,09611282 ! cofactor transport GO:0051181 8 8 0,000 0,05449696 0,09602094 ! regulation of acute inflammatory response GO:0002673 8 8 0,000 0,05449696 0,09592923 ! acid secretion GO:0046717 8 8 0,000 0,05449696 0,09583769 ! positive regulation of leukocyte migration GO:0002687 8 8 0,000 0,05449696 0,09574633 ! C21-steroid hormone biosynthetic process GO:0006700 8 8 0,000 0,05449696 0,09565514 ! protein-chromophore linkage GO:0018298 9 8 0,000 0,05449696 0,09556413 ! regulation of immunoglobulin production GO:0002637 8 8 0,000 0,05449696 0,09547329 ! catecholamine biosynthetic process GO:0042423 8 8 0,000 0,05449696 0,09538262 ! regulation of RNA stability GO:0043487 8 8 0,000 0,05449696 0,09529213 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 8 8 0,000 0,05449696 0,0952018 ! regulation of generation of precursor metabolites and energy GO:0043467 8 8 0,000 0,05449696 0,09511165 ! aromatic compound biosynthetic process GO:0019438 8 8 0,000 0,05449696 0,09502167 ! regulation of organic acid transport GO:0032890 8 8 0,000 0,05449696 0,09493185 ! positive regulation of calcium ion transport GO:0051928 8 8 0,000 0,05449696 0,09484221 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 8 8 0,000 0,05449696 0,09475274 ! regulation of multi-organism process GO:0043900 8 8 0,000 0,05449696 0,09466343 ! positive regulation of amine transport GO:0051954 8 8 0,000 0,05449696 0,09457429 ! developmental induction GO:0031128 8 8 0,000 0,05449696 0,09448533 GO:0045168|cell-cell signaling involved in cell fate specification, ! peptide hormone secretion GO:0030072 8 8 0,000 0,05449696 0,09439652 ! positive regulation of calcium-mediated signaling GO:0050850 8 8 0,000 0,05449696 0,09430789 ! actin filament polymerization GO:0030041 9 8 0,000 0,05449696 0,09421942 ! cytoplasmic sequestering of protein GO:0051220 8 8 0,000 0,05449696 0,09413112 ! peptide hormone processing GO:0016486 8 8 0,000 0,05449696 0,09404298 ! positive regulation of synaptic transmission GO:0050806 8 8 0,000 0,05449696 0,09395501 ! regulation of steroid biosynthetic process GO:0050810 8 8 0,000 0,05449696 0,0938672 ! microtubule cytoskeleton organization GO:0000226 55 55 1,000 0,05601936 0,09639932 ! embryonic pattern specification GO:0009880 10 9 0,000 0,06110117 0,10504614 ! positive regulation of cell size GO:0045793 9 9 0,000 0,06110117 0,10494824 ! positive regulation of cell projection organization GO:0031346 9 9 0,000 0,06110117 0,10485053 ! regulation of membrane protein ectodomain proteolysis GO:0051043 9 9 0,000 0,06110117 0,10475299 ! positive regulation of protein complex assembly GO:0031334 9 9 0,000 0,06110117 0,10465564 ! cortical actin cytoskeleton organization GO:0030866 10 9 0,000 0,06110117 0,10455846 ! viral genome replication GO:0019079 9 9 0,000 0,06110117 0,10446147 ! phospholipid catabolic process GO:0009395 9 9 0,000 0,06110117 0,10436466 ! copper ion transport GO:0006825 9 9 0,000 0,06110117 0,10426802 ! lipid phosphorylation GO:0046834 9 9 0,000 0,06110117 0,10417157 ! aminoglycan catabolic process GO:0006026 9 9 0,000 0,06110117 0,10407529 ! Golgi vesicle budding GO:0048194 9 9 0,000 0,06110117 0,10397919 ! regulation of cell-cell adhesion GO:0022407 9 9 0,000 0,06110117 0,10388327 ! RNA polyadenylation GO:0043631 9 9 0,000 0,06110117 0,10378752 GO:0006378|mRNA polyadenylation, ! gamma-aminobutyric acid signaling pathway GO:0007214 9 9 0,000 0,06110117 0,10369196 ! regulation of postsynaptic membrane potential GO:0060078 9 9 0,000 0,06110117 0,10359656 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 9 9 0,000 0,06110117 0,10350135 ! negative regulation of cytokine biosynthetic process GO:0042036 9 9 0,000 0,06110117 0,1034063 ! phospholipid efflux GO:0033700 9 9 0,000 0,06110117 0,10331143 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 9 9 0,000 0,06110117 0,10321674 ! cytokine biosynthetic process GO:0042089 9 9 0,000 0,06110117 0,10312222 GO:0042107|cytokine metabolic process, ! positive regulation of endothelial cell proliferation GO:0001938 9 9 0,000 0,06110117 0,10302787 ! negative regulation of gene expression, epigenetic GO:0045814 9 9 0,000 0,06110117 0,1029337 ! platelet-derived growth factor receptor signaling pathway GO:0048008 9 9 0,000 0,06110117 0,10283969 ! pyrimidine ribonucleotide metabolic process GO:0009218 9 9 0,000 0,06110117 0,10274586 ! methionine metabolic process GO:0006555 9 9 0,000 0,06110117 0,1026522 ! glutamine metabolic process GO:0006541 9 9 0,000 0,06110117 0,10255871 ! response to osmotic stress GO:0006970 9 9 0,000 0,06110117 0,10246539 ! pigmentation during development GO:0048066 9 9 0,000 0,06110117 0,10237224 ! reverse cholesterol transport GO:0043691 9 9 0,000 0,06110117 0,10227926 ! central nervous system neuron development GO:0021954 10 9 0,000 0,06110117 0,10218645 ! pyrimidine ribonucleoside metabolic process GO:0046131 9 9 0,000 0,06110117 0,1020938 ! nucleobase biosynthetic process GO:0046112 9 9 0,000 0,06110117 0,10200133 ! substrate-bound cell migration GO:0006929 9 9 0,000 0,06110117 0,10190902 ! neurotransmitter metabolic process GO:0042133 11 9 0,000 0,06110117 0,10181688 ! negative regulation of caspase activity GO:0043154 9 9 0,000 0,06110117 0,1017249 ! L-glutamate transport GO:0015813 9 9 0,000 0,06110117 0,10163309 GO:0015800|acidic amino acid transport, ! peptide secretion GO:0002790 9 9 0,000 0,06110117 0,10154145 ! regulation of dephosphorylation GO:0035303 9 9 0,000 0,06110117 0,10144997 ! cotranslational protein targeting to membrane GO:0006613 10 9 0,000 0,06110117 0,10135865 ! positive regulation of alpha-beta T cell differentiation GO:0046638 9 9 0,000 0,06110117 0,1012675 ! ventricular cardiac muscle morphogenesis GO:0055010 9 9 0,000 0,06110117 0,10117652 ! behavioral interaction between organisms GO:0051705 9 9 0,000 0,06110117 0,10108569 ! DNA replication initiation GO:0006270 9 9 0,000 0,06110117 0,10099503 ! prostaglandin metabolic process GO:0006693 9 9 0,000 0,06110117 0,10090454 GO:0006692|prostanoid metabolic process, ! regulation of cellular pH GO:0030641 9 9 0,000 0,06110117 0,1008142 ! regulation of immunoglobulin mediated immune response GO:0002889 9 9 0,000 0,06110117 0,10072403 GO:0002712|regulation of B cell mediated immunity, ! cellular amino acid derivative catabolic process GO:0042219 10 9 0,000 0,06110117 0,10063402 ! positive regulation of oxidoreductase activity GO:0051353 9 9 0,000 0,06110117 0,10054416 ! positive regulation of cytokine secretion GO:0050715 9 9 0,000 0,06110117 0,10045447 ! negative regulation of inflammatory response GO:0050728 9 9 0,000 0,06110117 0,10036494 ! negative regulation of protein secretion GO:0050709 9 9 0,000 0,06110117 0,10027557 ! regulation of leukocyte migration GO:0002685 9 9 0,000 0,06110117 0,10018636 ! positive regulation of transmission of nerve impulse GO:0051971 9 9 0,000 0,06110117 0,1000973 ! collagen catabolic process GO:0030574 9 9 0,000 0,06110117 0,1000084 ! aromatic amino acid family catabolic process GO:0009074 9 9 0,000 0,06110117 0,09991967 ! purine base metabolic process GO:0006144 9 9 0,000 0,06110117 0,09983109 ! gas transport GO:0015669 9 9 0,000 0,06110117 0,09974266 ! cholesterol efflux GO:0033344 9 9 0,000 0,06110117 0,09965439 ! regulation of leukocyte mediated cytotoxicity GO:0001910 9 9 0,000 0,06110117 0,09956628 ! estrogen receptor signaling pathway GO:0030520 9 9 0,000 0,06110117 0,09947833 ! somatic recombination of immunoglobulin gene segments GO:0016447 9 9 0,000 0,06110117 0,09939052 ! regulation of actin filament bundle formation GO:0032231 10 9 0,000 0,06110117 0,09930288 ! regulation of calcium-mediated signaling GO:0050848 9 9 0,000 0,06110117 0,09921539 ! actin filament-based movement GO:0030048 9 9 0,000 0,06110117 0,09912805 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 9 9 0,000 0,06110117 0,09904087 ! dephosphorylation GO:0016311 60 59 1,000 0,06343058 0,10272633 ! protein localization in organelle GO:0033365 59 59 1,000 0,06343058 0,10263614 ! potassium ion transport GO:0006813 60 60 1,000 0,06533315 0,10562193 ! proteasomal protein catabolic process GO:0010498 62 61 1,000 0,06725492 0,10863349 GO:0043161|proteasomal ubiquitin-dependent protein catabolic process, ! positive regulation of cellular protein metabolic process GO:0032270 61 61 1,000 0,06725492 0,10853837 ! protein import into nucleus, docking GO:0000059 10 10 0,000 0,06766021 0,10909691 ! regulation of protein ubiquitination GO:0031396 10 10 0,000 0,06766021 0,10900155 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 10 10 0,000 0,06766021 0,10890635 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 10 10 0,000 0,06766021 0,10881132 ! regulation of glucose metabolic process GO:0010906 10 10 0,000 0,06766021 0,10871645 ! ER-associated protein catabolic process GO:0030433 10 10 0,000 0,06766021 0,10862175 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of cell killing GO:0031341 10 10 0,000 0,06766021 0,10852721 ! pteridine and derivative metabolic process GO:0042558 10 10 0,000 0,06766021 0,10843284 ! positive regulation of anti-apoptosis GO:0045768 10 10 0,000 0,06766021 0,10833864 GO:0045767|regulation of anti-apoptosis, ! cortical cytoskeleton organization GO:0030865 11 10 0,000 0,06766021 0,10824459 ! regulation of lipid biosynthetic process GO:0046890 10 10 0,000 0,06766021 0,10815071 ! reciprocal meiotic recombination GO:0007131 10 10 0,000 0,06766021 0,10805699 ! hormone secretion GO:0046879 10 10 0,000 0,06766021 0,10796344 ! glucosamine metabolic process GO:0006041 10 10 0,000 0,06766021 0,10787004 GO:0006044|N-acetylglucosamine metabolic process, ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 10 10 0,000 0,06766021 0,10777681 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! inositol metabolic process GO:0006020 10 10 0,000 0,06766021 0,10768374 ! cAMP metabolic process GO:0046058 10 10 0,000 0,06766021 0,10759083 ! vesicle targeting, to, from or within Golgi GO:0048199 10 10 0,000 0,06766021 0,10749808 ! transcription from RNA polymerase III promoter GO:0006383 10 10 0,000 0,06766021 0,10740549 ! forelimb morphogenesis GO:0035136 10 10 0,000 0,06766021 0,10731305 ! phototransduction GO:0007602 11 10 0,000 0,06766021 0,10722078 ! calcium-independent cell-cell adhesion GO:0016338 10 10 0,000 0,06766021 0,10712867 ! auditory receptor cell differentiation GO:0042491 10 10 0,000 0,06766021 0,10703671 ! fat cell differentiation GO:0045444 10 10 0,000 0,06766021 0,10694491 ! myoblast differentiation GO:0045445 10 10 0,000 0,06766021 0,10685327 ! centrosome cycle GO:0007098 10 10 0,000 0,06766021 0,10676179 ! inactivation of MAPK activity GO:0000188 10 10 0,000 0,06766021 0,10667046 ! positive regulation of proteolysis GO:0045862 10 10 0,000 0,06766021 0,10657929 ! response to carbohydrate stimulus GO:0009743 10 10 0,000 0,06766021 0,10648827 ! protein polyubiquitination GO:0000209 10 10 0,000 0,06766021 0,10639741 ! glutamate metabolic process GO:0006536 11 10 0,000 0,06766021 0,10630671 ! plasma membrane organization GO:0007009 10 10 0,000 0,06766021 0,10621616 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 10 10 0,000 0,06766021 0,10612576 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! lysosomal transport GO:0007041 10 10 0,000 0,06766021 0,10603552 ! cellular response to unfolded protein GO:0034620 10 10 0,000 0,06766021 0,10594543 GO:0030968|endoplasmic reticulum unfolded protein response, ! central nervous system neuron differentiation GO:0021953 11 10 0,000 0,06766021 0,10585549 ! purine ribonucleoside metabolic process GO:0046128 10 10 0,000 0,06766021 0,10576571 GO:0042278|purine nucleoside metabolic process, ! vesicle coating GO:0006901 10 10 0,000 0,06766021 0,10567608 ! exocrine system development GO:0035272 10 10 0,000 0,06766021 0,1055866 ! embryo implantation GO:0007566 11 10 0,000 0,06766021 0,10549727 ! protein targeting to peroxisome GO:0006625 10 10 0,000 0,06766021 0,10540809 ! protein targeting to mitochondrion GO:0006626 10 10 0,000 0,06766021 0,10531906 GO:0070585|protein localization in mitochondrion, ! regulation of alpha-beta T cell differentiation GO:0046637 10 10 0,000 0,06766021 0,10523018 ! protein export from nucleus GO:0006611 10 10 0,000 0,06766021 0,10514146 ! negative regulation of immune response GO:0050777 10 10 0,000 0,06766021 0,10505288 ! cytolysis GO:0019835 10 10 0,000 0,06766021 0,10496445 ! positive regulation of biomineral formation GO:0070169 10 10 0,000 0,06766021 0,10487617 GO:0030501|positive regulation of bone mineralization, ! mismatch repair GO:0006298 10 10 0,000 0,06766021 0,10478804 ! histone deacetylation GO:0016575 10 10 0,000 0,06766021 0,10470006 ! mRNA splice site selection GO:0006376 11 10 0,000 0,06766021 0,10461222 ! synaptic vesicle transport GO:0048489 11 10 0,000 0,06766021 0,10452453 ! positive regulation of neurological system process GO:0031646 10 10 0,000 0,06766021 0,10443699 ! sphingolipid biosynthetic process GO:0030148 10 10 0,000 0,06766021 0,1043496 GO:0046467|membrane lipid biosynthetic process, ! sphingolipid catabolic process GO:0030149 10 10 0,000 0,06766021 0,10426235 GO:0046466|membrane lipid catabolic process, ! nerve-nerve synaptic transmission GO:0007270 10 10 0,000 0,06766021 0,10417525 ! regulation of epidermis development GO:0045682 10 10 0,000 0,06766021 0,10408829 ! folic acid and derivative metabolic process GO:0006760 10 10 0,000 0,06766021 0,10400148 ! negative regulation of neuron differentiation GO:0045665 10 10 0,000 0,06766021 0,10391481 ! aspartate family amino acid biosynthetic process GO:0009067 10 10 0,000 0,06766021 0,10382828 ! regulation of BMP signaling pathway GO:0030510 10 10 0,000 0,06766021 0,1037419 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 10 10 0,000 0,06766021 0,10365567 ! nerve development GO:0021675 10 10 0,000 0,06766021 0,10356958 ! embryonic organ morphogenesis GO:0048562 10 10 0,000 0,06766021 0,10348363 ! mRNA 3'-end processing GO:0031124 10 10 0,000 0,06766021 0,10339782 ! antigen receptor-mediated signaling pathway GO:0050851 10 10 0,000 0,06766021 0,10331215 ! negative regulation of coagulation GO:0050819 11 10 0,000 0,06766021 0,10322663 ! protein stabilization GO:0050821 10 10 0,000 0,06766021 0,10314125 ! morphogenesis of an epithelium GO:0002009 63 62 1,000 0,06919553 0,10539452 GO:0060429|epithelium development, ! protein import GO:0017038 62 62 1,000 0,06919553 0,10530749 ! negative regulation of cellular component organization GO:0051129 65 63 1,000 0,07115465 0,10819969 ! glucose metabolic process GO:0006006 63 63 1,000 0,07115465 0,10811049 ! regulation of response to external stimulus GO:0032101 65 64 1,000 0,07313194 0,1110232 ! positive regulation of protein metabolic process GO:0051247 64 64 1,000 0,07313194 0,11093183 ! protein secretion GO:0009306 11 11 0,000 0,07417438 0,11242054 ! oligosaccharide metabolic process GO:0009311 11 11 0,000 0,07417438 0,11232816 ! myeloid leukocyte differentiation GO:0002573 12 11 0,000 0,07417438 0,11223594 ! negative regulation of defense response GO:0031348 11 11 0,000 0,07417438 0,11214387 ! determination of bilateral symmetry GO:0009855 11 11 0,000 0,07417438 0,11205195 GO:0009799|determination of symmetry, GO:0007368|determination of left/right symmetry, ! positive regulation of hormone secretion GO:0046887 11 11 0,000 0,07417438 0,11196018 ! phosphatidylinositol metabolic process GO:0046488 11 11 0,000 0,07417438 0,11186856 ! skin development GO:0043588 11 11 0,000 0,07417438 0,11177708 ! cellular component assembly involved in morphogenesis GO:0010927 11 11 0,000 0,07417438 0,11168576 ! signal complex assembly GO:0007172 11 11 0,000 0,07417438 0,11159459 ! microtubule-based transport GO:0010970 11 11 0,000 0,07417438 0,11150357 ! endothelial cell migration GO:0043542 11 11 0,000 0,07417438 0,11141269 ! peroxisomal transport GO:0043574 11 11 0,000 0,07417438 0,11132197 ! protein amino acid methylation GO:0006479 11 11 0,000 0,07417438 0,11123139 GO:0008213|protein amino acid alkylation, ! heart contraction GO:0060047 11 11 0,000 0,07417438 0,11114095 GO:0003015|heart process, ! detection of light stimulus involved in sensory perception GO:0050962 12 11 0,000 0,07417438 0,11105067 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! dendrite development GO:0016358 11 11 0,000 0,07417438 0,11096053 ! regulation of transmembrane transporter activity GO:0022898 11 11 0,000 0,07417438 0,11087054 GO:0032412|regulation of ion transmembrane transporter activity, GO:0032409|regulation of transporter activity, ! activation of MAPKK activity GO:0000186 12 11 0,000 0,07417438 0,11078069 ! smooth muscle contraction GO:0006939 11 11 0,000 0,07417438 0,11069099 ! cellular response to starvation GO:0009267 11 11 0,000 0,07417438 0,11060144 ! cellular macromolecular complex disassembly GO:0034623 12 11 0,000 0,07417438 0,11051202 ! digestive system process GO:0022600 11 11 0,000 0,07417438 0,11042276 ! mitotic spindle organization GO:0007052 11 11 0,000 0,07417438 0,11033364 ! fucose metabolic process GO:0006004 11 11 0,000 0,07417438 0,11024466 ! membrane budding GO:0006900 11 11 0,000 0,07417438 0,11015582 ! monoamine transport GO:0015844 11 11 0,000 0,07417438 0,11006713 ! regulation of cellular ketone metabolic process GO:0010565 11 11 0,000 0,07417438 0,10997858 ! response to lipopolysaccharide GO:0032496 11 11 0,000 0,07417438 0,10989017 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 11 11 0,000 0,07417438 0,10980191 ! body fluid secretion GO:0007589 11 11 0,000 0,07417438 0,10971378 ! G1/S transition checkpoint GO:0031575 12 11 0,000 0,07417438 0,1096258 ! positive regulation of alpha-beta T cell activation GO:0046635 11 11 0,000 0,07417438 0,10953796 ! cardiac muscle tissue morphogenesis GO:0055008 11 11 0,000 0,07417438 0,10945026 GO:0060415|muscle tissue morphogenesis, ! interaction with host GO:0051701 11 11 0,000 0,07417438 0,1093627 ! membrane depolarization GO:0051899 11 11 0,000 0,07417438 0,10927528 ! regulation of ARF GTPase activity GO:0032312 11 11 0,000 0,07417438 0,109188 ! negative regulation of angiogenesis GO:0016525 11 11 0,000 0,07417438 0,10910086 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 11 11 0,000 0,07417438 0,10901386 ! regulation of cellular carbohydrate metabolic process GO:0010675 11 11 0,000 0,07417438 0,10892699 GO:0006109|regulation of carbohydrate metabolic process, ! vitamin transport GO:0051180 11 11 0,000 0,07417438 0,10884027 ! muscle maintenance GO:0046716 12 11 0,000 0,07417438 0,10875368 ! vitamin A metabolic process GO:0006776 11 11 0,000 0,07417438 0,10866723 ! steroid catabolic process GO:0006706 11 11 0,000 0,07417438 0,10858092 ! endocrine process GO:0050886 11 11 0,000 0,07417438 0,10849474 GO:0001990|regulation of systemic arterial blood pressure by hormone, ! aromatic amino acid family metabolic process GO:0009072 11 11 0,000 0,07417438 0,1084087 ! proximal/distal pattern formation GO:0009954 11 11 0,000 0,07417438 0,1083228 ! somatic diversification of immunoglobulins GO:0016445 11 11 0,000 0,07417438 0,10823703 ! RNA 3'-end processing GO:0031123 11 11 0,000 0,07417438 0,1081514 ! positive regulation of cellular component organization GO:0051130 65 65 1,000 0,07512706 0,10945389 ! polysaccharide metabolic process GO:0005976 69 66 1,000 0,07713967 0,11229732 ! positive regulation of protein catabolic process GO:0045732 12 12 0,000 0,08064397 0,1173061 ! translational initiation GO:0006413 12 12 0,000 0,08064397 0,11721359 ! positive regulation of angiogenesis GO:0045766 12 12 0,000 0,08064397 0,11712122 ! iron ion transport GO:0006826 13 12 0,000 0,08064397 0,117029 ! phosphatidylcholine metabolic process GO:0046470 12 12 0,000 0,08064397 0,11693693 ! amino sugar metabolic process GO:0006040 12 12 0,000 0,08064397 0,11684499 ! post-Golgi vesicle-mediated transport GO:0006892 12 12 0,000 0,08064397 0,11675321 ! protein amino acid ADP-ribosylation GO:0006471 12 12 0,000 0,08064397 0,11666156 ! heterophilic cell adhesion GO:0007157 12 12 0,000 0,08064397 0,11657007 ! collagen metabolic process GO:0032963 12 12 0,000 0,08064397 0,11647871 ! hindlimb morphogenesis GO:0035137 12 12 0,000 0,08064397 0,1163875 ! xenobiotic metabolic process GO:0006805 12 12 0,000 0,08064397 0,11629643 ! glutamate signaling pathway GO:0007215 12 12 0,000 0,08064397 0,1162055 ! C21-steroid hormone metabolic process GO:0008207 13 12 0,000 0,08064397 0,11611471 ! regulation of muscle cell differentiation GO:0051147 13 12 0,000 0,08064397 0,11602407 ! cellular response to hydrogen peroxide GO:0070301 12 12 0,000 0,08064397 0,11593357 GO:0042744|hydrogen peroxide catabolic process, ! negative regulation of peptidase activity GO:0010466 12 12 0,000 0,08064397 0,11584321 ! actomyosin structure organization GO:0031032 12 12 0,000 0,08064397 0,11575299 ! microtubule organizing center organization GO:0031023 12 12 0,000 0,08064397 0,11566291 GO:0051297|centrosome organization, ! positive regulation of endocytosis GO:0045807 12 12 0,000 0,08064397 0,11557297 ! retinoid metabolic process GO:0001523 12 12 0,000 0,08064397 0,11548316 GO:0016101|diterpenoid metabolic process, ! mitotic chromosome condensation GO:0007076 12 12 0,000 0,08064397 0,1153935 ! positive regulation of innate immune response GO:0045089 12 12 0,000 0,08064397 0,11530398 ! GPI anchor biosynthetic process GO:0006506 12 12 0,000 0,08064397 0,1152146 GO:0006505|GPI anchor metabolic process, ! glycoprotein catabolic process GO:0006516 13 12 0,000 0,08064397 0,11512535 ! acute-phase response GO:0006953 12 12 0,000 0,08064397 0,11503625 ! deoxyribonucleotide catabolic process GO:0009264 12 12 0,000 0,08064397 0,11494728 ! vacuolar transport GO:0007034 12 12 0,000 0,08064397 0,11485845 ! polysaccharide catabolic process GO:0000272 12 12 0,000 0,08064397 0,11476976 ! vesicle docking during exocytosis GO:0006904 12 12 0,000 0,08064397 0,1146812 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 12 12 0,000 0,08064397 0,11459278 ! barbed-end actin filament capping GO:0051016 12 12 0,000 0,08064397 0,11450449 GO:0051693|actin filament capping, ! regulation of insulin secretion GO:0050796 12 12 0,000 0,08064397 0,11441635 ! regulation of alpha-beta T cell activation GO:0046634 12 12 0,000 0,08064397 0,11432833 ! regulation of tumor necrosis factor production GO:0032680 12 12 0,000 0,08064397 0,11424046 ! regulation of interleukin-6 production GO:0032675 12 12 0,000 0,08064397 0,11415271 ! cell fate determination GO:0001709 12 12 0,000 0,08064397 0,11406511 ! regulation of response to biotic stimulus GO:0002831 12 12 0,000 0,08064397 0,11397763 ! positive regulation of adaptive immune response GO:0002821 12 12 0,000 0,08064397 0,11389029 ! detection of light stimulus GO:0009583 13 12 0,000 0,08064397 0,11380309 ! synaptogenesis GO:0007416 12 12 0,000 0,08064397 0,11371602 ! fat-soluble vitamin metabolic process GO:0006775 12 12 0,000 0,08064397 0,11362908 ! hormone transport GO:0009914 12 12 0,000 0,08064397 0,11354227 ! neurotransmitter secretion GO:0007269 14 12 0,000 0,08064397 0,1134556 ! heme biosynthetic process GO:0006783 12 12 0,000 0,08064397 0,11336906 ! spermatid differentiation GO:0048515 13 12 0,000 0,08064397 0,11328265 GO:0007286|spermatid development, ! aromatic compound catabolic process GO:0019439 13 12 0,000 0,08064397 0,11319637 ! pyrimidine nucleotide biosynthetic process GO:0006221 12 12 0,000 0,08064397 0,11311022 ! neural tube closure GO:0001843 13 12 0,000 0,08064397 0,11302421 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! negative regulation of translation GO:0017148 12 12 0,000 0,08064397 0,11293832 ! regulation of microtubule polymerization or depolymerization GO:0031110 12 12 0,000 0,08064397 0,11285257 ! cellular monovalent inorganic cation homeostasis GO:0030004 12 12 0,000 0,08064397 0,11276694 ! sensory perception of sound GO:0007605 71 69 1,000 0,08327921 0,1163636 GO:0050954|sensory perception of mechanical stimulus, ! regionalization GO:0003002 70 69 1,000 0,08327921 0,11627545 ! response to nutrient levels GO:0031667 69 69 1,000 0,08327921 0,11618743 ! positive regulation of DNA replication GO:0045740 14 13 0,000 0,08706929 0,12138328 ! positive regulation of smooth muscle cell proliferation GO:0048661 13 13 0,000 0,08706929 0,12129153 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 13 13 0,000 0,08706929 0,12119992 GO:0016444|somatic cell DNA recombination, ! negative regulation of actin filament polymerization GO:0030837 13 13 0,000 0,08706929 0,12110845 ! phenol metabolic process GO:0018958 13 13 0,000 0,08706929 0,12101712 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, GO:0009712|catechol metabolic process, ! gluconeogenesis GO:0006094 13 13 0,000 0,08706929 0,12092592 ! negative regulation of hormone secretion GO:0046888 13 13 0,000 0,08706929 0,12083486 ! 2'-deoxyribonucleotide metabolic process GO:0009394 13 13 0,000 0,08706929 0,12074394 GO:0019692|deoxyribose phosphate metabolic process, ! intra-Golgi vesicle-mediated transport GO:0006891 13 13 0,000 0,08706929 0,12065315 ! glycosaminoglycan biosynthetic process GO:0006024 13 13 0,000 0,08706929 0,12056251 ! keratinization GO:0031424 13 13 0,000 0,08706929 0,12047199 ! negative regulation of protein modification process GO:0031400 13 13 0,000 0,08706929 0,12038162 ! vasculogenesis GO:0001570 13 13 0,000 0,08706929 0,12029138 ! regulation of innate immune response GO:0045088 13 13 0,000 0,08706929 0,12020127 ! negative regulation of DNA replication GO:0008156 13 13 0,000 0,08706929 0,1201113 ! multicellular organismal macromolecule metabolic process GO:0044259 13 13 0,000 0,08706929 0,12002146 ! multicellular organismal catabolic process GO:0044243 13 13 0,000 0,08706929 0,11993176 ! autophagy GO:0006914 13 13 0,000 0,08706929 0,11984219 ! receptor metabolic process GO:0043112 14 13 0,000 0,08706929 0,11975276 ! negative regulation of protein catabolic process GO:0042177 13 13 0,000 0,08706929 0,11966346 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 13 13 0,000 0,08706929 0,11957429 ! coenzyme catabolic process GO:0009109 13 13 0,000 0,08706929 0,11948525 GO:0046356|acetyl-CoA catabolic process, GO:0006099|tricarboxylic acid cycle, ! purine nucleoside monophosphate metabolic process GO:0009126 13 13 0,000 0,08706929 0,11939635 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of peptide secretion GO:0002791 13 13 0,000 0,08706929 0,11930758 ! nucleobase metabolic process GO:0009112 13 13 0,000 0,08706929 0,11921894 ! regulation of axonogenesis GO:0050770 14 13 0,000 0,08706929 0,11913043 ! positive regulation of neurogenesis GO:0050769 13 13 0,000 0,08706929 0,11904206 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 14 13 0,000 0,08706929 0,11895381 ! nucleotide-excision repair, DNA gap filling GO:0006297 13 13 0,000 0,08706929 0,1188657 ! vasodilation GO:0042311 14 13 0,000 0,08706929 0,11877772 ! positive regulation of leukocyte mediated immunity GO:0002705 13 13 0,000 0,08706929 0,11868986 GO:0002708|positive regulation of lymphocyte mediated immunity, ! negative regulation of phosphorylation GO:0042326 13 13 0,000 0,08706929 0,11860214 ! glycosphingolipid metabolic process GO:0006687 13 13 0,000 0,08706929 0,11851455 GO:0006664|glycolipid metabolic process, ! positive regulation of locomotion GO:0040017 13 13 0,000 0,08706929 0,11842708 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, GO:0050920|regulation of chemotaxis, ! neural crest cell migration GO:0001755 14 13 0,000 0,08706929 0,11833975 ! neutrophil chemotaxis GO:0030593 14 13 0,000 0,08706929 0,11825254 ! long-chain fatty acid transport GO:0015909 13 13 0,000 0,08706929 0,11816546 ! immunoglobulin production GO:0002377 13 13 0,000 0,08706929 0,11807851 GO:0002440|production of molecular mediator of immune response, ! negative regulation of Wnt receptor signaling pathway GO:0030178 13 13 0,000 0,08706929 0,11799169 ! cell-cell junction organization GO:0045216 13 13 0,000 0,08706929 0,11790499 ! activation of JUN kinase activity GO:0007257 13 13 0,000 0,08706929 0,11781843 ! terpenoid metabolic process GO:0006721 13 13 0,000 0,08706929 0,11773199 ! alkene biosynthetic process GO:0043450 13 13 0,000 0,08706929 0,11764567 GO:0019370|leukotriene biosynthetic process, ! purine nucleotide catabolic process GO:0006195 13 13 0,000 0,08706929 0,11755948 ! porphyrin biosynthetic process GO:0006779 13 13 0,000 0,08706929 0,11747342 GO:0033014|tetrapyrrole biosynthetic process, ! negative regulation of cytokine production GO:0001818 13 13 0,000 0,08706929 0,11738749 ! pyrimidine nucleoside metabolic process GO:0006213 13 13 0,000 0,08706929 0,11730168 ! blastocyst development GO:0001824 13 13 0,000 0,08706929 0,11721599 ! telomere organization GO:0032200 13 13 0,000 0,08706929 0,11713043 GO:0000723|telomere maintenance, ! water-soluble vitamin biosynthetic process GO:0042364 13 13 0,000 0,08706929 0,117045 ! regulation of amine transport GO:0051952 13 13 0,000 0,08706929 0,11695969 ! inner ear receptor cell differentiation GO:0060113 13 13 0,000 0,08706929 0,11687451 ! protein tetramerization GO:0051262 13 13 0,000 0,08706929 0,11678944 ! negative regulation of signal transduction GO:0009968 71 71 1,000 0,08745379 0,11721988 ! response to extracellular stimulus GO:0009991 72 72 1,000 0,08956459 0,11996188 ! regulation of cytokine production GO:0001817 72 72 1,000 0,08956459 0,11987476 ! neuron fate commitment GO:0048663 14 14 0,000 0,09345063 0,12498513 ! sulfur amino acid metabolic process GO:0000096 14 14 0,000 0,09345063 0,12489449 ! regulation of interferon-gamma production GO:0032649 14 14 0,000 0,09345063 0,12480399 ! pyruvate metabolic process GO:0006090 14 14 0,000 0,09345063 0,12471362 ! cellular aldehyde metabolic process GO:0006081 14 14 0,000 0,09345063 0,12462338 ! acetyl-CoA metabolic process GO:0006084 14 14 0,000 0,09345063 0,12453327 ! cellular iron ion homeostasis GO:0006879 14 14 0,000 0,09345063 0,12444329 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 14 14 0,000 0,09345063 0,12435344 ! regulation of neuron projection development GO:0010975 15 14 0,000 0,09345063 0,12426371 ! protein amino acid deacetylation GO:0006476 14 14 0,000 0,09345063 0,12417412 ! aminoglycan biosynthetic process GO:0006023 14 14 0,000 0,09345063 0,12408466 ! vesicle docking GO:0048278 14 14 0,000 0,09345063 0,12399533 ! superoxide metabolic process GO:0006801 15 14 0,000 0,09345063 0,12390612 ! macromolecular complex disassembly GO:0032984 15 14 0,000 0,09345063 0,12381704 ! calcium-dependent cell-cell adhesion GO:0016339 14 14 0,000 0,09345063 0,1237281 ! mechanoreceptor differentiation GO:0042490 14 14 0,000 0,09345063 0,12363927 ! isoprenoid biosynthetic process GO:0008299 14 14 0,000 0,09345063 0,12355058 ! immune response-activating cell surface receptor signaling pathway GO:0002429 14 14 0,000 0,09345063 0,12346201 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! response to retinoic acid GO:0032526 14 14 0,000 0,09345063 0,12337357 GO:0033189|response to vitamin A, ! lysosome organization GO:0007040 14 14 0,000 0,09345063 0,12328526 ! actin polymerization or depolymerization GO:0008154 15 14 0,000 0,09345063 0,12319707 ! D-ribose metabolic process GO:0006014 14 14 0,000 0,09345063 0,12310901 ! negative regulation of phosphorus metabolic process GO:0010563 14 14 0,000 0,09345063 0,12302108 GO:0045936|negative regulation of phosphate metabolic process, ! peptide transport GO:0015833 14 14 0,000 0,09345063 0,12293327 ! primary neural tube formation GO:0014020 15 14 0,000 0,09345063 0,12284558 ! peptide cross-linking GO:0018149 14 14 0,000 0,09345063 0,12275802 ! regulation of behavior GO:0050795 14 14 0,000 0,09345063 0,12267059 ! vitamin biosynthetic process GO:0009110 14 14 0,000 0,09345063 0,12258328 ! base-excision repair GO:0006284 14 14 0,000 0,09345063 0,12249609 ! leukotriene metabolic process GO:0006691 14 14 0,000 0,09345063 0,12240903 ! regulation of vasoconstriction GO:0019229 14 14 0,000 0,09345063 0,12232209 ! formation of primary germ layer GO:0001704 14 14 0,000 0,09345063 0,12223528 GO:0001707|mesoderm formation, ! proteoglycan biosynthetic process GO:0030166 14 14 0,000 0,09345063 0,12214859 ! regulation of blood coagulation GO:0030193 15 14 0,000 0,09345063 0,12206202 ! group transfer coenzyme metabolic process GO:0006752 14 14 0,000 0,09345063 0,12197557 ! positive regulation of osteoblast differentiation GO:0045669 14 14 0,000 0,09345063 0,12188925 ! neuromuscular process controlling balance GO:0050885 14 14 0,000 0,09345063 0,12180305 ! aspartate family amino acid metabolic process GO:0009066 14 14 0,000 0,09345063 0,12171697 ! response to molecule of bacterial origin GO:0002237 14 14 0,000 0,09345063 0,12163101 ! negative regulation of protein polymerization GO:0032272 14 14 0,000 0,09345063 0,12154517 ! negative regulation of cell communication GO:0010648 76 76 1,000 0,09815745 0,12757699 ! protein import into nucleus, translocation GO:0000060 15 15 0,000 0,09978829 0,12960523 ! negative regulation of actin filament depolymerization GO:0030835 15 15 0,000 0,09978829 0,12951395 ! positive regulation of ossification GO:0045778 15 15 0,000 0,09978829 0,12942281 GO:0046852|positive regulation of bone remodeling, GO:0034105|positive regulation of tissue remodeling, ! negative regulation of protein complex assembly GO:0031333 15 15 0,000 0,09978829 0,1293318 ! protein amino acid O-linked glycosylation GO:0006493 15 15 0,000 0,09978829 0,12924091 ! cellular polysaccharide biosynthetic process GO:0033692 15 15 0,000 0,09978829 0,12915015 ! proteoglycan metabolic process GO:0006029 15 15 0,000 0,09978829 0,12905952 ! response to vitamin GO:0033273 15 15 0,000 0,09978829 0,12896901 ! odontogenesis of dentine-containing tooth GO:0042475 15 15 0,000 0,09978829 0,12887864 ! detection of stimulus involved in sensory perception GO:0050906 16 15 0,000 0,09978829 0,12878839 ! antigen processing and presentation of peptide antigen GO:0048002 15 15 0,000 0,09978829 0,12869826 ! regulation of smooth muscle contraction GO:0006940 15 15 0,000 0,09978829 0,12860826 ! deoxyribonucleotide metabolic process GO:0009262 15 15 0,000 0,09978829 0,12851839 ! complement activation, classical pathway GO:0006958 15 15 0,000 0,09978829 0,12842864 ! heme metabolic process GO:0042168 15 15 0,000 0,09978829 0,12833902 ! mesoderm morphogenesis GO:0048332 15 15 0,000 0,09978829 0,12824952 ! chromosome condensation GO:0030261 15 15 0,000 0,09978829 0,12816015 ! response to starvation GO:0042594 15 15 0,000 0,09978829 0,1280709 ! response to mechanical stimulus GO:0009612 15 15 0,000 0,09978829 0,12798178 ! hydrogen peroxide metabolic process GO:0042743 15 15 0,000 0,09978829 0,12789278 ! regulation of biomineral formation GO:0070167 15 15 0,000 0,09978829 0,1278039 GO:0030500|regulation of bone mineralization, ! regulation of production of molecular mediator of immune response GO:0002700 15 15 0,000 0,09978829 0,12771515 ! cyclic nucleotide biosynthetic process GO:0009190 15 15 0,000 0,09978829 0,12762652 ! cholesterol biosynthetic process GO:0006695 15 15 0,000 0,09978829 0,12753801 ! phospholipid transport GO:0015914 15 15 0,000 0,09978829 0,12744963 ! regulation of cytokine secretion GO:0050707 15 15 0,000 0,09978829 0,12736137 ! glutathione metabolic process GO:0006749 16 15 0,000 0,09978829 0,12727323 ! nicotinamide metabolic process GO:0006769 15 15 0,000 0,09978829 0,12718521 GO:0046496|nicotinamide nucleotide metabolic process, ! positive regulation of myeloid cell differentiation GO:0045639 16 15 0,000 0,09978829 0,12709732 ! cellular alkene metabolic process GO:0043449 15 15 0,000 0,09978829 0,12700954 ! negative regulation of transcription factor activity GO:0043433 16 15 0,000 0,09978829 0,12692189 GO:0090048|negative regulation of transcription regulator activity, ! somatic diversification of immune receptors GO:0002200 15 15 0,000 0,09978829 0,12683436 ! positive regulation of immune effector process GO:0002699 15 15 0,000 0,09978829 0,12674694 ! nuclear transport GO:0051169 79 79 1,000 0,10475085 0,13295855 GO:0006913|nucleocytoplasmic transport, ! negative regulation of adenylate cyclase activity GO:0007194 16 16 0,000 0,10608256 0,1345562 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! alkaloid metabolic process GO:0009820 16 16 0,000 0,10608256 0,13446365 ! spliceosomal snRNP biogenesis GO:0000387 16 16 0,000 0,10608256 0,13437124 ! circadian rhythm GO:0007623 16 16 0,000 0,10608256 0,13427895 ! inner ear morphogenesis GO:0042472 16 16 0,000 0,10608256 0,13418679 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 16 16 0,000 0,10608256 0,13409476 ! vacuole organization GO:0007033 16 16 0,000 0,10608256 0,13400285 ! positive regulation of cytoskeleton organization GO:0051495 16 16 0,000 0,10608256 0,13391106 ! vesicle targeting GO:0006903 17 16 0,000 0,10608256 0,13381941 ! fatty acid beta-oxidation GO:0006635 16 16 0,000 0,10608256 0,13372788 ! triglyceride metabolic process GO:0006641 16 16 0,000 0,10608256 0,13363647 ! iron ion homeostasis GO:0055072 16 16 0,000 0,10608256 0,13354519 ! regulation of myeloid leukocyte differentiation GO:0002761 17 16 0,000 0,10608256 0,13345403 ! regulation of systemic arterial blood pressure GO:0003073 17 16 0,000 0,10608256 0,133363 ! cell fate specification GO:0001708 16 16 0,000 0,10608256 0,13327209 ! pentose metabolic process GO:0019321 16 16 0,000 0,10608256 0,1331813 ! fatty acid transport GO:0015908 16 16 0,000 0,10608256 0,13309064 ! positive regulation of MAPKKK cascade GO:0043410 17 16 0,000 0,10608256 0,1330001 ! cellular response to nutrient levels GO:0031669 16 16 0,000 0,10608256 0,13290969 ! regulation of microtubule cytoskeleton organization GO:0070507 16 16 0,000 0,10608256 0,1328194 ! cofactor catabolic process GO:0051187 16 16 0,000 0,10608256 0,13272923 ! ethanolamine and derivative metabolic process GO:0042439 17 16 0,000 0,10608256 0,13263918 ! polyol metabolic process GO:0019751 16 16 0,000 0,10608256 0,13254926 ! serine family amino acid metabolic process GO:0009069 16 16 0,000 0,10608256 0,13245945 ! glutamine family amino acid catabolic process GO:0009065 17 16 0,000 0,10608256 0,13236977 ! porphyrin metabolic process GO:0006778 16 16 0,000 0,10608256 0,13228021 GO:0033013|tetrapyrrole metabolic process, ! embryonic epithelial tube formation GO:0001838 17 16 0,000 0,10608256 0,13219077 GO:0001841|neural tube formation, ! positive regulation of catabolic process GO:0009896 16 16 0,000 0,10608256 0,13210146 ! regulation of JUN kinase activity GO:0043506 17 16 0,000 0,10608256 0,13201226 GO:0043507|positive regulation of JUN kinase activity, ! regulation of cell morphogenesis involved in differentiation GO:0010769 17 16 0,000 0,10608256 0,13192318 ! response to xenobiotic stimulus GO:0009410 16 16 0,000 0,10608256 0,13183422 ! regulation of coagulation GO:0050818 17 16 0,000 0,10608256 0,13174539 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 17 17 0,000 0,11233373 0,13941486 ! regulation of smooth muscle cell proliferation GO:0048660 17 17 0,000 0,11233373 0,13932104 ! regulation of actin filament depolymerization GO:0030834 17 17 0,000 0,11233373 0,13922735 ! phosphoinositide biosynthetic process GO:0046489 17 17 0,000 0,11233373 0,13913378 ! regulation of transmembrane transport GO:0034762 17 17 0,000 0,11233373 0,13904034 ! nucleotide-excision repair, DNA damage removal GO:0000718 18 17 0,000 0,11233373 0,13894702 ! leukocyte adhesion GO:0007159 17 17 0,000 0,11233373 0,13885383 ! sensory perception of smell GO:0007608 17 17 0,000 0,11233373 0,13876077 ! tissue remodeling GO:0048771 17 17 0,000 0,11233373 0,13866782 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 17 17 0,000 0,11233373 0,13857501 ! embryonic skeletal system morphogenesis GO:0048704 17 17 0,000 0,11233373 0,13848232 ! cellular carbohydrate biosynthetic process GO:0034637 17 17 0,000 0,11233373 0,13838975 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 17 17 0,000 0,11233373 0,1382973 ! neural crest cell development GO:0014032 19 17 0,000 0,11233373 0,13820498 GO:0014033|neural crest cell differentiation, ! immune response-activating signal transduction GO:0002757 17 17 0,000 0,11233373 0,13811278 GO:0002764|immune response-regulating signal transduction, ! cell recognition GO:0008037 18 17 0,000 0,11233373 0,13802071 ! positive regulation of protein secretion GO:0050714 17 17 0,000 0,11233373 0,13792876 ! pyridine nucleotide metabolic process GO:0019362 17 17 0,000 0,11233373 0,13783693 ! myeloid leukocyte activation GO:0002274 18 17 0,000 0,11233373 0,13774522 ! adult locomotory behavior GO:0008344 17 17 0,000 0,11233373 0,13765363 ! embryonic organ development GO:0048568 17 17 0,000 0,11233373 0,13756217 ! regulation of calcium ion transport GO:0051924 17 17 0,000 0,11233373 0,13747082 ! gene silencing GO:0016458 17 17 0,000 0,11233373 0,1373796 ! ncRNA processing GO:0034470 83 83 1,000 0,11372561 0,13898959 ! positive regulation of response to stimulus GO:0048584 86 85 1,000 0,11828665 0,14446806 ! mRNA export from nucleus GO:0006406 18 18 0,000 0,11854209 0,14468415 ! regulation of cell projection organization GO:0031344 19 18 0,000 0,11854209 0,1445884 ! regulation of cellular catabolic process GO:0031329 18 18 0,000 0,11854209 0,14449277 ! icosanoid biosynthetic process GO:0046456 18 18 0,000 0,11854209 0,14439727 ! regulation of metal ion transport GO:0010959 18 18 0,000 0,11854209 0,1443019 ! membrane docking GO:0022406 18 18 0,000 0,11854209 0,14420665 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 18 18 0,000 0,11854209 0,14411152 ! response to calcium ion GO:0051592 18 18 0,000 0,11854209 0,14401653 ! negative regulation of response to external stimulus GO:0032102 18 18 0,000 0,11854209 0,14392165 ! cholesterol homeostasis GO:0042632 18 18 0,000 0,11854209 0,14382691 GO:0055092|sterol homeostasis, ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 18 18 0,000 0,11854209 0,14373228 ! striated muscle contraction GO:0006941 18 18 0,000 0,11854209 0,14363779 ! neutral lipid metabolic process GO:0006638 18 18 0,000 0,11854209 0,14354341 GO:0006639|acylglycerol metabolic process, ! negative regulation of DNA binding GO:0043392 19 18 0,000 0,11854209 0,14344916 ! ceramide metabolic process GO:0006672 18 18 0,000 0,11854209 0,14335503 GO:0046519|sphingoid metabolic process, ! ribonucleoside monophosphate metabolic process GO:0009161 18 18 0,000 0,11854209 0,14326103 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! hexose biosynthetic process GO:0019319 18 18 0,000 0,11854209 0,14316715 ! cellular response to extracellular stimulus GO:0031668 18 18 0,000 0,11854209 0,14307339 ! BMP signaling pathway GO:0030509 18 18 0,000 0,11854209 0,14297976 ! regulation of microtubule-based process GO:0032886 18 18 0,000 0,11854209 0,14288625 ! negative regulation of catabolic process GO:0009895 18 18 0,000 0,11854209 0,14279286 ! symbiosis, encompassing mutualism through parasitism GO:0044403 18 18 0,000 0,11854209 0,14269959 ! establishment of vesicle localization GO:0051650 19 18 0,000 0,11854209 0,14260644 ! activation of adenylate cyclase activity GO:0007190 19 19 0,000 0,12470793 0,1499261 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 19 19 0,000 0,12470793 0,14982836 GO:0006956|complement activation, ! negative regulation of DNA metabolic process GO:0051053 19 19 0,000 0,12470793 0,14973076 ! regulation of pH GO:0006885 19 19 0,000 0,12470793 0,14963328 ! feeding behavior GO:0007631 19 19 0,000 0,12470793 0,14953592 ! peroxisome organization GO:0007031 19 19 0,000 0,12470793 0,14943869 ! ribonucleoside metabolic process GO:0009119 19 19 0,000 0,12470793 0,14934159 ! regulation of lymphocyte mediated immunity GO:0002706 19 19 0,000 0,12470793 0,14924462 ! positive regulation of T cell differentiation GO:0045582 19 19 0,000 0,12470793 0,14914777 ! nuclear-transcribed mRNA catabolic process GO:0000956 19 19 0,000 0,12470793 0,14905104 ! hormone biosynthetic process GO:0042446 19 19 0,000 0,12470793 0,14895445 ! biogenic amine biosynthetic process GO:0042401 20 19 0,000 0,12470793 0,14885797 ! dorsal/ventral pattern formation GO:0009953 19 19 0,000 0,12470793 0,14876163 ! regulation of cell shape GO:0008360 21 19 0,000 0,12470793 0,1486654 ! placenta development GO:0001890 19 19 0,000 0,12470793 0,1485693 ! vesicle localization GO:0051648 20 19 0,000 0,12470793 0,14847333 ! chemotaxis GO:0006935 90 89 1,000 0,12754532 0,15175341 GO:0042330|taxis, ! negative regulation of cell adhesion GO:0007162 21 20 0,000 0,13083153 0,15556291 ! negative regulation of binding GO:0051100 21 20 0,000 0,13083153 0,15546261 ! organic ether metabolic process GO:0018904 20 20 0,000 0,13083153 0,15536244 GO:0006662|glycerol ether metabolic process, ! cytoskeleton-dependent intracellular transport GO:0030705 20 20 0,000 0,13083153 0,1552624 ! neural tube development GO:0021915 21 20 0,000 0,13083153 0,15516249 ! phagocytosis GO:0006909 21 20 0,000 0,13083153 0,1550627 ! positive regulation of gene-specific transcription GO:0043193 20 20 0,000 0,13083153 0,15496305 ! unsaturated fatty acid biosynthetic process GO:0006636 20 20 0,000 0,13083153 0,15486352 ! protein targeting to membrane GO:0006612 22 20 0,000 0,13083153 0,15476412 ! cyclic nucleotide metabolic process GO:0009187 20 20 0,000 0,13083153 0,15466485 ! detection of abiotic stimulus GO:0009582 21 20 0,000 0,13083153 0,15456571 ! lipid oxidation GO:0034440 20 20 0,000 0,13083153 0,15446669 GO:0019395|fatty acid oxidation, ! monosaccharide biosynthetic process GO:0046364 20 20 0,000 0,13083153 0,1543678 ! single fertilization GO:0007338 21 20 0,000 0,13083153 0,15426904 ! energy derivation by oxidation of organic compounds GO:0015980 94 92 1,000 0,1346007 0,15861195 ! positive regulation of immune system process GO:0002684 92 92 1,000 0,1346007 0,15851061 ! mRNA catabolic process GO:0006402 21 21 0,000 0,13691317 0,16113089 ! protein amino acid lipidation GO:0006497 21 21 0,000 0,13691317 0,16102806 ! receptor-mediated endocytosis GO:0006898 21 21 0,000 0,13691317 0,16092537 ! Notch signaling pathway GO:0007219 22 21 0,000 0,13691317 0,1608228 ! morphogenesis of embryonic epithelium GO:0016331 22 21 0,000 0,13691317 0,16072037 ! ear morphogenesis GO:0042471 21 21 0,000 0,13691317 0,16061806 ! organic anion transport GO:0015711 21 21 0,000 0,13691317 0,16051589 ! cholesterol transport GO:0030301 21 21 0,000 0,13691317 0,16041384 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 22 21 0,000 0,13691317 0,16031193 ! regulation of Rab protein signal transduction GO:0032483 21 21 0,000 0,13691317 0,16021014 GO:0032313|regulation of Rab GTPase activity, ! regulation of leukocyte mediated immunity GO:0002703 21 21 0,000 0,13691317 0,16010849 ! regulation of proteolysis GO:0030162 21 21 0,000 0,13691317 0,16000696 ! negative regulation of hydrolase activity GO:0051346 21 21 0,000 0,13691317 0,15990556 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 21 21 0,000 0,13691317 0,15980429 ! tissue morphogenesis GO:0048729 94 93 1,000 0,13697237 0,15977221 ! regulation of response to stress GO:0080134 97 94 1,000 0,13935357 0,16244695 ! RNA export from nucleus GO:0006405 22 22 0,000 0,14295314 0,1665377 ! positive regulation of DNA metabolic process GO:0051054 23 22 0,000 0,14295314 0,1664325 ! regulation of ion transport GO:0043269 22 22 0,000 0,14295314 0,16632743 ! odontogenesis GO:0042476 22 22 0,000 0,14295314 0,16622249 ! hormone-mediated signaling GO:0009755 22 22 0,000 0,14295314 0,16611768 ! embryonic skeletal system development GO:0048706 22 22 0,000 0,14295314 0,16601301 ! maintenance of protein location in cell GO:0032507 23 22 0,000 0,14295314 0,16590847 ! pigment biosynthetic process GO:0046148 22 22 0,000 0,14295314 0,16580406 ! cell chemotaxis GO:0060326 23 22 0,000 0,14295314 0,16569978 GO:0030595|leukocyte chemotaxis, ! respiratory gaseous exchange GO:0007585 22 22 0,000 0,14295314 0,16559563 ! erythrocyte differentiation GO:0030218 23 22 0,000 0,14295314 0,16549161 ! sterol biosynthetic process GO:0016126 22 22 0,000 0,14295314 0,16538773 ! regulation of adaptive immune response GO:0002819 22 22 0,000 0,14295314 0,16528397 ! detection of external stimulus GO:0009581 23 22 0,000 0,14295314 0,16518034 ! regulation of Wnt receptor signaling pathway GO:0030111 23 22 0,000 0,14295314 0,16507685 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 22 22 0,000 0,14295314 0,16497348 ! fatty acid catabolic process GO:0009062 23 22 0,000 0,14295314 0,16487024 ! aerobic respiration GO:0009060 22 22 0,000 0,14295314 0,16476713 ! cytokine production GO:0001816 22 22 0,000 0,14295314 0,16466415 ! pyrimidine nucleotide metabolic process GO:0006220 22 22 0,000 0,14295314 0,1645613 ! regulation of cell growth GO:0001558 97 96 1,000 0,1441436 0,16582813 ! epithelial cell differentiation GO:0030855 23 23 0,000 0,14895172 0,17125267 ! regulation of hormone secretion GO:0046883 23 23 0,000 0,14895172 0,1711459 ! negative regulation of protein complex disassembly GO:0043242 23 23 0,000 0,14895172 0,17103927 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 23 23 0,000 0,14895172 0,17093277 ! regulation of ARF protein signal transduction GO:0032012 23 23 0,000 0,14895172 0,1708264 ! lipoprotein biosynthetic process GO:0042158 23 23 0,000 0,14895172 0,17072017 ! monovalent inorganic cation homeostasis GO:0055067 23 23 0,000 0,14895172 0,17061406 ! lipid homeostasis GO:0055088 23 23 0,000 0,14895172 0,17050809 ! Rho protein signal transduction GO:0007266 24 23 0,000 0,14895172 0,17040225 ! regulation of JNK cascade GO:0046328 25 23 0,000 0,14895172 0,17029654 ! posttranscriptional regulation of gene expression GO:0010608 98 98 1,000 0,1489689 0,17021059 ! regulation of system process GO:0044057 98 98 1,000 0,1489689 0,17010513 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 26 24 0,000 0,15490919 0,17677872 ! cellular amino acid biosynthetic process GO:0008652 24 24 0,000 0,15490919 0,17666932 ! glucose homeostasis GO:0042593 24 24 0,000 0,15490919 0,17656007 GO:0033500|carbohydrate homeostasis, ! heterocycle biosynthetic process GO:0018130 24 24 0,000 0,15490919 0,17645094 ! nucleotide catabolic process GO:0009166 24 24 0,000 0,15490919 0,17634196 ! erythrocyte homeostasis GO:0034101 25 24 0,000 0,15490919 0,1762331 ! fertilization GO:0009566 25 24 0,000 0,15490919 0,17612439 ! maintenance of protein location GO:0045185 25 24 0,000 0,15490919 0,1760158 ! oxidoreduction coenzyme metabolic process GO:0006733 24 24 0,000 0,15490919 0,17590735 ! regulation of actin filament polymerization GO:0030833 25 25 0,000 0,16082581 0,18251352 ! negative regulation of secretion GO:0051048 26 25 0,000 0,16082581 0,18240121 ! protein amino acid N-linked glycosylation GO:0006487 25 25 0,000 0,16082581 0,18228903 ! regulation of gene-specific transcription GO:0032583 25 25 0,000 0,16082581 0,18217699 ! sensory perception of chemical stimulus GO:0007606 25 25 0,000 0,16082581 0,18206509 ! endosome transport GO:0016197 25 25 0,000 0,16082581 0,18195332 ! alcohol biosynthetic process GO:0046165 25 25 0,000 0,16082581 0,18184169 ! polysaccharide biosynthetic process GO:0000271 25 25 0,000 0,16082581 0,1817302 ! excretion GO:0007588 25 25 0,000 0,16082581 0,18161885 ! generation of a signal involved in cell-cell signaling GO:0003001 27 25 0,000 0,16082581 0,18150763 ! gastrulation GO:0007369 25 25 0,000 0,16082581 0,18139655 ! heart morphogenesis GO:0003007 25 25 0,000 0,16082581 0,1812856 ! icosanoid metabolic process GO:0006690 25 25 0,000 0,16082581 0,18117479 ! regulation of endocytosis GO:0030100 25 25 0,000 0,16082581 0,18106412 ! positive regulation of cytokine production GO:0001819 25 25 0,000 0,16082581 0,18095358 ! transforming growth factor beta receptor signaling pathway GO:0007179 26 26 0,000 0,16670186 0,1874506 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 26 26 0,000 0,16670186 0,1873363 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 26 26 0,000 0,16670186 0,18722214 ! cellular defense response GO:0006968 26 26 0,000 0,16670186 0,18710812 ! double-strand break repair GO:0006302 27 26 0,000 0,16670186 0,18699424 ! regulation of protein secretion GO:0050708 26 26 0,000 0,16670186 0,18688049 ! regulation of blood vessel size GO:0050880 27 26 0,000 0,16670186 0,18676689 GO:0035150|regulation of tube size, ! maintenance of location in cell GO:0051651 27 26 0,000 0,16670186 0,18665342 ! chloride transport GO:0006821 27 27 0,000 0,17253762 0,19307033 ! regulation of neurotransmitter levels GO:0001505 31 27 0,000 0,17253762 0,19295318 ! monocarboxylic acid transport GO:0015718 27 27 0,000 0,17253762 0,19283617 ! cAMP-mediated signaling GO:0019933 27 27 0,000 0,17253762 0,1927193 ! peptide metabolic process GO:0006518 29 27 0,000 0,17253762 0,19260257 ! activation of caspase activity GO:0006919 27 27 0,000 0,17253762 0,19248598 ! inner ear development GO:0048839 27 27 0,000 0,17253762 0,19236954 ! defense response to bacterium GO:0042742 27 27 0,000 0,17253762 0,19225323 ! isoprenoid metabolic process GO:0006720 27 27 0,000 0,17253762 0,19213706 ! glutamine family amino acid metabolic process GO:0009064 28 27 0,000 0,17253762 0,19202104 ! tRNA aminoacylation for protein translation GO:0006418 28 28 0,000 0,17833336 0,19835147 GO:0043038|amino acid activation, GO:0043039|tRNA aminoacylation, ! stress-activated protein kinase signaling pathway GO:0031098 28 28 0,000 0,17833336 0,19823184 GO:0007254|JNK cascade, ! neuromuscular process GO:0050905 28 28 0,000 0,17833336 0,19811235 ! regulation of muscle contraction GO:0006937 28 28 0,000 0,17833336 0,197993 ! unsaturated fatty acid metabolic process GO:0033559 28 28 0,000 0,17833336 0,1978738 ! sulfur compound biosynthetic process GO:0044272 28 28 0,000 0,17833336 0,19775475 ! cartilage development GO:0051216 29 28 0,000 0,17833336 0,19763583 ! glycerophospholipid biosynthetic process GO:0046474 30 29 0,000 0,18408935 0,20389223 ! phosphoinositide metabolic process GO:0030384 29 29 0,000 0,18408935 0,20376977 ! leukocyte migration GO:0050900 30 29 0,000 0,18408935 0,20364746 ! antigen processing and presentation GO:0019882 29 29 0,000 0,18408935 0,20352529 ! DNA-dependent DNA replication GO:0006261 29 29 0,000 0,18408935 0,20340328 ! adult behavior GO:0030534 30 29 0,000 0,18408935 0,2032814 ! regulation of protein polymerization GO:0032271 29 29 0,000 0,18408935 0,20315968 ! transition metal ion transport GO:0000041 31 30 0,000 0,18980584 0,20934301 ! RNA catabolic process GO:0006401 30 30 0,000 0,18980584 0,2092178 ! ER to Golgi vesicle-mediated transport GO:0006888 30 30 0,000 0,18980584 0,20909275 ! positive regulation of peptidase activity GO:0010952 30 30 0,000 0,18980584 0,20896784 GO:0043280|positive regulation of caspase activity, ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 30 30 0,000 0,18980584 0,20884308 ! neuropeptide signaling pathway GO:0007218 30 30 0,000 0,18980584 0,20871848 ! regulation of protein complex disassembly GO:0043244 30 30 0,000 0,18980584 0,20859402 ! skeletal system morphogenesis GO:0048705 31 30 0,000 0,18980584 0,20846971 ! vascular process in circulatory system GO:0003018 31 30 0,000 0,18980584 0,20834554 ! immunoglobulin mediated immune response GO:0016064 30 30 0,000 0,18980584 0,20822153 GO:0019724|B cell mediated immunity, ! water-soluble vitamin metabolic process GO:0006767 30 30 0,000 0,18980584 0,20809766 ! cellular amino acid derivative biosynthetic process GO:0042398 31 30 0,000 0,18980584 0,20797394 ! regulation of translational initiation GO:0006446 31 31 0,000 0,19548311 0,21406737 ! membrane fusion GO:0006944 31 31 0,000 0,19548311 0,21394025 ! negative regulation of cytoskeleton organization GO:0051494 32 31 0,000 0,19548311 0,21381328 ! lipoprotein metabolic process GO:0042157 31 31 0,000 0,19548311 0,21368646 ! ion transmembrane transport GO:0034220 31 31 0,000 0,19548311 0,2135598 GO:0015985|energy coupled proton transport, down electrochemical gradient, GO:0015986|ATP synthesis coupled proton transport, ! glycerolipid biosynthetic process GO:0045017 32 31 0,000 0,19548311 0,21343328 ! digestion GO:0007586 31 31 0,000 0,19548311 0,21330692 ! nucleoside metabolic process GO:0009116 31 31 0,000 0,19548311 0,2131807 ! regulation of heart contraction GO:0008016 31 31 0,000 0,19548311 0,21305463 ! sphingolipid metabolic process GO:0006665 31 31 0,000 0,19548311 0,21292871 ! ribonucleoprotein complex assembly GO:0022618 32 31 0,000 0,19548311 0,21280294 ! cell redox homeostasis GO:0045454 32 32 0,000 0,20112143 0,21881157 ! lipid modification GO:0030258 32 32 0,000 0,20112143 0,21868247 ! glycosaminoglycan metabolic process GO:0030203 34 32 0,000 0,20112143 0,21855353 ! regulation of vesicle-mediated transport GO:0060627 33 32 0,000 0,20112143 0,21842474 ! nuclear export GO:0051168 32 32 0,000 0,20112143 0,21829611 ! protein maturation by peptide bond cleavage GO:0051605 32 32 0,000 0,20112143 0,21816762 ! maintenance of location GO:0051235 33 32 0,000 0,20112143 0,21803929 ! regulation of cellular response to stress GO:0080135 35 33 0,000 0,20672104 0,22397818 ! amino acid transport GO:0006865 33 33 0,000 0,20672104 0,22384658 ! regulation of protein complex assembly GO:0043254 33 33 0,000 0,20672104 0,22371514 ! membrane lipid metabolic process GO:0006643 33 33 0,000 0,20672104 0,22358385 ! regulation of actin polymerization or depolymerization GO:0008064 33 33 0,000 0,20672104 0,22345272 ! regulation of actin filament length GO:0030832 34 34 0,000 0,21228222 0,22932951 ! regulation of protein catabolic process GO:0042176 35 34 0,000 0,21228222 0,22919516 ! coenzyme biosynthetic process GO:0009108 34 34 0,000 0,21228222 0,22906097 ! nucleoside monophosphate biosynthetic process GO:0009124 34 34 0,000 0,21228222 0,22892694 ! negative regulation of response to stimulus GO:0048585 34 34 0,000 0,21228222 0,22879306 ! detection of stimulus GO:0051606 36 34 0,000 0,21228222 0,22865934 ! acute inflammatory response GO:0002526 35 35 0,000 0,21780522 0,23447139 ! regulation of cellular component size GO:0032535 35 35 0,000 0,21780522 0,23433452 ! mesoderm development GO:0007498 35 35 0,000 0,21780522 0,2341978 ! regulation of cell morphogenesis GO:0022604 38 35 0,000 0,21780522 0,23406124 ! inorganic anion transport GO:0015698 35 35 0,000 0,21780522 0,23392484 ! regulation of immune effector process GO:0002697 35 35 0,000 0,21780522 0,2337886 ! hydrogen transport GO:0006818 36 36 0,000 0,2232903 0,23953668 GO:0015992|proton transport, ! aminoglycan metabolic process GO:0006022 38 36 0,000 0,2232903 0,23939734 ! embryonic limb morphogenesis GO:0030326 36 36 0,000 0,2232903 0,23925815 GO:0035113|embryonic appendage morphogenesis, ! RNA elongation from RNA polymerase II promoter GO:0006368 36 36 0,000 0,2232903 0,23911913 ! heterocycle catabolic process GO:0046700 36 36 0,000 0,2232903 0,23898027 ! activation of immune response GO:0002253 36 36 0,000 0,2232903 0,23884157 ! coagulation GO:0050817 39 36 0,000 0,2232903 0,23870303 GO:0007596|blood coagulation, ! lymphocyte mediated immunity GO:0002449 37 37 0,000 0,22873771 0,24438469 ! ATP synthesis coupled electron transport GO:0042773 37 37 0,000 0,22873771 0,2442431 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! cellular amino acid catabolic process GO:0009063 38 37 0,000 0,22873771 0,24410168 ! adaptive immune response GO:0002250 37 37 0,000 0,22873771 0,24396041 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! positive regulation of secretion GO:0051047 39 38 0,000 0,2341477 0,24958601 ! neurotransmitter transport GO:0006836 40 38 0,000 0,2341477 0,24944174 ! cellular hormone metabolic process GO:0034754 39 38 0,000 0,2341477 0,24929764 ! exocytosis GO:0006887 40 38 0,000 0,2341477 0,2491537 ! RNA elongation GO:0006354 38 38 0,000 0,2341477 0,24900993 ! hemostasis GO:0007599 42 39 0,000 0,23952053 0,2545769 ! nucleoside monophosphate metabolic process GO:0009123 39 39 0,000 0,23952053 0,25443017 ! fatty acid biosynthetic process GO:0006633 39 39 0,000 0,23952053 0,25428361 ! nucleotide-excision repair GO:0006289 40 39 0,000 0,23952053 0,25413721 ! intracellular protein transmembrane transport GO:0065002 39 39 0,000 0,23952053 0,25399099 ! limb development GO:0060173 39 39 0,000 0,23952053 0,25384494 GO:0048736|appendage development, GO:0035107|appendage morphogenesis, ! myeloid cell differentiation GO:0030099 42 40 0,000 0,24485645 0,25935083 ! amine catabolic process GO:0009310 42 41 0,000 0,2501557 0,26481158 ! phospholipid biosynthetic process GO:0008654 42 41 0,000 0,2501557 0,26465956 ! leukocyte mediated immunity GO:0002443 41 41 0,000 0,2501557 0,26450772 ! respiratory electron transport chain GO:0022904 43 42 0,000 0,25541854 0,26991764 ! protein ubiquitination GO:0016567 43 42 0,000 0,25541854 0,26976296 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 43 43 0,000 0,2606452 0,27512549 ! mRNA transport GO:0051028 44 44 0,000 0,26583593 0,28044397 ! vitamin metabolic process GO:0006766 44 44 0,000 0,26583593 0,28028354 ! amine biosynthetic process GO:0009309 46 45 0,000 0,27099097 0,28555538 ! regulation of actin cytoskeleton organization GO:0032956 46 45 0,000 0,27099097 0,28539221 ! steroid biosynthetic process GO:0006694 46 45 0,000 0,27099097 0,28522922 ! protein processing GO:0016485 45 45 0,000 0,27099097 0,28506642 ! regulation of actin filament-based process GO:0032970 47 46 0,000 0,27611057 0,29028624 ! cyclic-nucleotide-mediated signaling GO:0019935 46 46 0,000 0,27611057 0,29012074 ! transcription initiation from RNA polymerase II promoter GO:0006367 46 46 0,000 0,27611057 0,28995543 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 47 47 0,000 0,28119496 0,2951266 ! regulation of blood pressure GO:0008217 48 47 0,000 0,28119496 0,29495862 ! amine transport GO:0015837 47 47 0,000 0,28119496 0,29479084 ! regulation of catabolic process GO:0009894 48 47 0,000 0,28119496 0,29462325 ! calcium ion transport GO:0006816 48 48 0,000 0,28624437 0,29974339 ! glycerophospholipid metabolic process GO:0006650 49 48 0,000 0,28624437 0,29957318 ! DNA recombination GO:0006310 48 48 0,000 0,28624437 0,29940316 ! cellular lipid catabolic process GO:0044242 50 49 0,000 0,29125905 0,30447556 ! divalent metal ion transport GO:0070838 49 49 0,000 0,29125905 0,30430296 ! response to bacterium GO:0009617 50 49 0,000 0,29125905 0,30413055 ! cofactor biosynthetic process GO:0051188 49 49 0,000 0,29125905 0,30395834 ! chromatin assembly GO:0031497 50 50 0,000 0,29623922 0,30898069 GO:0006334|nucleosome assembly, ! RNA transport GO:0050658 50 50 0,000 0,29623922 0,30880593 GO:0050657|nucleic acid transport, GO:0051236|establishment of RNA localization, ! nitrogen compound catabolic process GO:0044270 51 50 0,000 0,29623922 0,30863136 ! transcription initiation GO:0006352 50 50 0,000 0,29623922 0,30845699 ! biogenic amine metabolic process GO:0006576 52 51 0,000 0,30118512 0,3134298 ! protein modification by small protein conjugation GO:0032446 52 51 0,000 0,30118512 0,31325292 ! positive regulation of immune response GO:0050778 51 51 0,000 0,30118512 0,31307624 ! rRNA metabolic process GO:0016072 51 51 0,000 0,30118512 0,31289976 GO:0006364|rRNA processing, ! protein-DNA complex assembly GO:0065004 51 51 0,000 0,30118512 0,31272348 ! ATP biosynthetic process GO:0006754 51 51 0,000 0,30118512 0,3125474 ! protein maturation GO:0051604 51 51 0,000 0,30118512 0,31237151 ! RNA localization GO:0006403 52 52 0,000 0,30609699 0,31728726 ! cholesterol metabolic process GO:0008203 52 52 0,000 0,30609699 0,31710891 ! regulation of body fluid levels GO:0050878 55 52 0,000 0,30609699 0,31693075 ! sodium ion transport GO:0006814 53 53 0,000 0,31097504 0,32180067 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 53 53 0,000 0,31097504 0,32162009 ! carbohydrate biosynthetic process GO:0016051 53 53 0,000 0,31097504 0,32143971 ! hormone metabolic process GO:0042445 55 54 0,000 0,31581951 0,32626421 ! nucleosome organization GO:0034728 55 55 0,000 0,32063062 0,33104887 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 55 55 0,000 0,32063062 0,33086351 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! in utero embryonic development GO:0001701 55 55 0,000 0,32063062 0,33067836 ! protein modification by small protein conjugation or removal GO:0070647 56 55 0,000 0,32063062 0,33049342 ! ribonucleoside triphosphate biosynthetic process GO:0009201 56 56 0,000 0,3254086 0,33523089 ! ATP metabolic process GO:0046034 57 57 0,000 0,33015368 0,33992918 ! nucleoside triphosphate biosynthetic process GO:0009142 57 57 0,000 0,33015368 0,33973938 ! innate immune response GO:0045087 58 58 0,000 0,33486607 0,3443963 ! carboxylic acid transport GO:0046942 59 59 0,000 0,33954599 0,34901464 GO:0015849|organic acid transport, ! sterol metabolic process GO:0016125 59 59 0,000 0,33954599 0,3488201 ! cellular aromatic compound metabolic process GO:0006725 60 59 0,000 0,33954599 0,34862577 ! negative regulation of cellular protein metabolic process GO:0032269 60 60 0,000 0,34419366 0,35320096 ! protein polymerization GO:0051258 65 60 0,000 0,34419366 0,35300441 ! cellular respiration GO:0045333 62 61 0,000 0,34880931 0,35753924 ! carboxylic acid catabolic process GO:0046395 63 61 0,000 0,34880931 0,3573405 GO:0016054|organic acid catabolic process, ! lipid transport GO:0006869 62 62 0,000 0,35339314 0,36183531 ! purine ribonucleoside triphosphate metabolic process GO:0009205 62 62 0,000 0,35339314 0,3616344 ! regulation of cellular component biogenesis GO:0044087 63 62 0,000 0,35339314 0,36143372 ! di-, tri-valent inorganic cation transport GO:0015674 63 62 0,000 0,35339314 0,36123326 ! regulation of secretion GO:0051046 65 63 0,000 0,35794538 0,36568366 ! ribonucleoside triphosphate metabolic process GO:0009199 63 63 0,000 0,35794538 0,36548107 ! purine nucleoside triphosphate metabolic process GO:0009144 63 63 0,000 0,35794538 0,3652787 ! glycerolipid metabolic process GO:0046486 65 64 0,000 0,36246622 0,36968747 ! regulation of cytoskeleton organization GO:0051493 66 64 0,000 0,36246622 0,36948299 ! anion transport GO:0006820 65 65 0,000 0,3669559 0,3738528 ! regulation of hormone levels GO:0010817 66 65 0,000 0,3669559 0,37364625 ! protein amino acid glycosylation GO:0006486 66 66 0,000 0,37141461 0,37797743 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! nucleoside triphosphate metabolic process GO:0009141 66 66 0,000 0,37141461 0,37776883 ! DNA packaging GO:0006323 66 66 0,000 0,37141461 0,37756047 ! negative regulation of protein metabolic process GO:0051248 66 66 0,000 0,37141461 0,37735233 ! Golgi vesicle transport GO:0048193 67 67 0,000 0,37584257 0,38164069 ! muscle contraction GO:0006936 67 67 0,000 0,37584257 0,38143053 ! purine ribonucleotide biosynthetic process GO:0009152 68 68 0,000 0,38023998 0,38568095 ! chromatin assembly or disassembly GO:0006333 68 68 0,000 0,38023998 0,3854688 ! regulation of translation GO:0006417 69 69 0,000 0,38460705 0,38968158 ! carboxylic acid biosynthetic process GO:0046394 70 70 0,000 0,38894398 0,39385921 GO:0016053|organic acid biosynthetic process, ! translational elongation GO:0006414 71 71 0,000 0,39325098 0,39800196 ! oxidative phosphorylation GO:0006119 71 71 0,000 0,39325098 0,39778352 ! ribosome biogenesis GO:0042254 71 71 0,000 0,39325098 0,39756531 ! secretion by cell GO:0032940 75 72 0,000 0,39752826 0,40166918 ! muscle system process GO:0003012 72 72 0,000 0,39752826 0,40144908 ! electron transport chain GO:0022900 75 74 0,000 0,40599442 0,40977421 ! coenzyme metabolic process GO:0006732 75 74 0,000 0,40599442 0,40954992 ! ribonucleotide biosynthetic process GO:0009260 75 75 0,000 0,4101837 0,41354954 ! purine ribonucleotide metabolic process GO:0009150 75 75 0,000 0,4101837 0,41332343 ! microtubule-based movement GO:0007018 82 78 0,000 0,42257873 0,42558066 ! regulation of immune response GO:0050776 78 78 0,000 0,42257873 0,42534823 ! glycoprotein biosynthetic process GO:0009101 80 80 0,000 0,4307 0,43328608 ! lipid catabolic process GO:0016042 82 81 0,000 0,43471859 0,43709022 ! ribonucleotide metabolic process GO:0009259 83 83 0,000 0,44267262 0,44484495 ! nitrogen compound biosynthetic process GO:0044271 86 85 0,000 0,45051702 0,45248113 ! organophosphate metabolic process GO:0019637 87 86 0,000 0,45439858 0,45613104 GO:0006644|phospholipid metabolic process, ! male gamete generation GO:0048232 90 88 0,000 0,46208132 0,46359057 GO:0007283|spermatogenesis, ! purine nucleotide biosynthetic process GO:0006164 88 88 0,000 0,46208132 0,46333834 ! DNA replication GO:0006260 91 91 0,000 0,4734072 0,47443691 ! visual perception GO:0007601 93 92 0,000 0,47713035 0,47790828 GO:0050953|sensory perception of light stimulus, ! cofactor metabolic process GO:0051186 95 94 0,000 0,48449949 0,48502583 ! glycoprotein metabolic process GO:0009100 99 98 0,000 0,49893396 0,49920482 ! blood circulation GO:0008015 99 98 0,000 0,49893396 0,49893396 GO:0003013|circulatory system process,