pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6408-Loi-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! nuclear migration GO:0007097 12 6 2,000 3,324E-07 7,996E-04 ! positive regulation of pseudopodium assembly GO:0031274 14 6 2,000 3,324E-07 3,998E-04 GO:0031272|regulation of pseudopodium assembly, ! protein amino acid autophosphorylation GO:0046777 141 60 4,000 4,998E-07 4,009E-04 ! regulation of lipid kinase activity GO:0043550 13 7 2,000 5,805E-07 3,492E-04 ! macrophage differentiation GO:0030225 11 7 2,000 5,805E-07 2,794E-04 ! phosphoinositide 3-kinase cascade GO:0014065 32 8 2,000 9,271E-07 3,718E-04 ! establishment of nucleus localization GO:0040023 16 8 2,000 9,271E-07 3,187E-04 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 23 10 2,000 1,979E-06 5,953E-04 ! nucleus localization GO:0051647 19 11 2,000 2,716E-06 7,262E-04 ! regulation of cell projection assembly GO:0060491 30 12 2,000 3,615E-06 8,698E-04 ! G1/S transition of mitotic cell cycle GO:0000082 115 46 3,000 6,254E-06 1,368E-03 ! epithelial to mesenchymal transition GO:0001837 28 15 2,000 7,435E-06 1,491E-03 ! filopodium assembly GO:0046847 32 16 2,000 9,134E-06 1,69E-03 ! positive regulation of nitric oxide biosynthetic process GO:0045429 35 17 2,000 1,107E-05 1,902E-03 ! microspike assembly GO:0030035 36 17 2,000 1,107E-05 1,776E-03 ! regulation of nitric oxide biosynthetic process GO:0045428 40 20 2,000 1,846E-05 2,775E-03 ! viral reproductive process GO:0022415 126 62 3,000 2,072E-05 2,932E-03 ! regulation of lipid metabolic process GO:0019216 115 63 3,000 2,208E-05 2,951E-03 ! positive regulation of epithelial cell proliferation GO:0050679 64 22 2,000 2,484E-05 3,145E-03 ! negative regulation of protein kinase activity GO:0006469 130 67 3,000 2,819E-05 3,391E-03 ! myeloid leukocyte differentiation GO:0002573 40 23 2,000 2,851E-05 3,266E-03 ! negative regulation of kinase activity GO:0033673 131 68 3,000 2,989E-05 3,269E-03 ! intracellular receptor-mediated signaling pathway GO:0030522 139 68 3,000 2,989E-05 3,127E-03 ! viral reproduction GO:0016032 134 68 3,000 2,989E-05 2,996E-03 ! interaction with host GO:0051701 62 25 2,000 3,689E-05 3,55E-03 ! negative regulation of transferase activity GO:0051348 140 72 3,000 3,746E-05 3,467E-03 ! insulin receptor signaling pathway GO:0008286 64 26 2,000 4,162E-05 3,709E-03 ! positive regulation of cell projection organization GO:0031346 58 27 2,000 4,674E-05 4,016E-03 ! negative regulation of protein complex assembly GO:0031333 59 29 2,000 5,817E-05 4,826E-03 ! positive regulation of glycolysis GO:0045821 14 5 1,000 6,588E-05 5,284E-03 ! regulation of phospholipase A2 activity GO:0032429 13 5 1,000 6,588E-05 5,113E-03 ! muscle cell proliferation GO:0033002 11 5 1,000 6,588E-05 4,954E-03 ! positive regulation of catabolic process GO:0009896 64 32 2,000 7,852E-05 5,725E-03 ! symbiosis, encompassing mutualism through parasitism GO:0044403 73 34 2,000 9,438E-05 6,679E-03 ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 24 6 1,000 9,866E-05 6,782E-03 ! activation of MAPKKK activity GO:0000185 12 6 1,000 9,866E-05 6,594E-03 ! male sex determination GO:0030238 15 6 1,000 9,866E-05 6,416E-03 ! negative regulation of gliogenesis GO:0014014 18 6 1,000 9,866E-05 6,247E-03 GO:0045686|negative regulation of glial cell differentiation, ! progesterone metabolic process GO:0042448 10 6 1,000 9,866E-05 6,087E-03 ! positive regulation of MAP kinase activity GO:0043406 160 93 3,000 1,02E-04 6,138E-03 ! interphase of mitotic cell cycle GO:0051329 209 95 3,000 1,108E-04 6,503E-03 ! androgen receptor signaling pathway GO:0030521 74 36 2,000 1,122E-04 6,427E-03 ! establishment or maintenance of cell polarity GO:0007163 83 37 2,000 1,219E-04 6,819E-03 ! cellular response to insulin stimulus GO:0032869 82 37 2,000 1,219E-04 6,664E-03 ! interphase GO:0051325 213 98 3,000 1,25E-04 6,684E-03 ! regulation of protein export from nucleus GO:0046825 10 7 1,000 1,379E-04 7,212E-03 ! N-terminal protein amino acid acetylation GO:0006474 13 7 1,000 1,379E-04 7,059E-03 ! regulation of respiratory burst GO:0060263 11 7 1,000 1,379E-04 6,912E-03 ! mesenchymal cell development GO:0014031 87 40 2,000 1,541E-04 7,566E-03 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of intracellular protein transport GO:0033157 80 42 2,000 1,784E-04 8,584E-03 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 22 8 1,000 1,835E-04 8,659E-03 ! cerebral cortex neuron differentiation GO:0021895 16 8 1,000 1,835E-04 8,493E-03 ! cardiac muscle cell differentiation GO:0055007 27 8 1,000 1,835E-04 8,332E-03 ! regulation of T cell differentiation in the thymus GO:0033081 13 8 1,000 1,835E-04 8,178E-03 ! regulation of epithelial cell proliferation GO:0050678 111 43 2,000 1,914E-04 8,373E-03 ! regulation of nucleocytoplasmic transport GO:0046822 85 46 2,000 2,341E-04 0,01005875 ! response to insulin stimulus GO:0032868 95 46 2,000 2,341E-04 9,882E-03 ! regulation of developmental growth GO:0048638 15 9 1,000 2,356E-04 9,773E-03 ! positive regulation of glucose metabolic process GO:0010907 18 9 1,000 2,356E-04 9,607E-03 ! regulation of glycolysis GO:0006110 21 9 1,000 2,356E-04 9,447E-03 ! insulin-like growth factor receptor signaling pathway GO:0048009 24 9 1,000 2,356E-04 9,292E-03 ! retinoic acid receptor signaling pathway GO:0048384 15 9 1,000 2,356E-04 9,143E-03 ! motor axon guidance GO:0008045 16 9 1,000 2,356E-04 8,997E-03 ! protein heterooligomerization GO:0051291 16 9 1,000 2,356E-04 8,857E-03 ! regulation of mast cell proliferation GO:0070666 81 48 2,000 2,658E-04 9,837E-03 ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 20 10 1,000 2,94E-04 0,01071751 ! positive regulation of B cell proliferation GO:0030890 16 10 1,000 2,94E-04 0,01055755 ! regulation of gliogenesis GO:0014013 23 10 1,000 2,94E-04 0,01040229 GO:0045685|regulation of glial cell differentiation, ! regulation of cellular carbohydrate catabolic process GO:0043471 22 10 1,000 2,94E-04 0,01025153 GO:0043470|regulation of carbohydrate catabolic process, ! localization within membrane GO:0051668 20 10 1,000 2,94E-04 0,01010508 ! regulation of cell projection organization GO:0031344 121 50 2,000 3E-04 0,01016774 ! viral infectious cycle GO:0019058 99 51 2,000 3,182E-04 0,01063338 ! regulation of leukocyte proliferation GO:0070663 88 51 2,000 3,182E-04 0,01048771 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! response to UV GO:0009411 104 53 2,000 3,566E-04 0,01159495 ! regulation of nitric-oxide synthase activity GO:0050999 26 11 1,000 3,587E-04 0,01150792 ! peptide or protein amino-terminal blocking GO:0018409 21 11 1,000 3,587E-04 0,0113565 ! neuroblast proliferation GO:0007405 24 11 1,000 3,587E-04 0,01120901 ! cardiac cell differentiation GO:0035051 31 11 1,000 3,587E-04 0,0110653 ! regulation of embryonic development GO:0045995 27 11 1,000 3,587E-04 0,01092524 ! heart morphogenesis GO:0003007 97 55 2,000 3,979E-04 0,0119668 ! positive regulation of cellular catabolic process GO:0031331 31 12 1,000 4,297E-04 0,0127651 ! virus-host interaction GO:0019048 29 12 1,000 4,297E-04 0,01260942 ! regulation of B cell proliferation GO:0030888 20 12 1,000 4,297E-04 0,0124575 ! hippocampus development GO:0021766 26 12 1,000 4,297E-04 0,0123092 ! positive regulation of transcription factor import into nucleus GO:0042993 23 12 1,000 4,297E-04 0,01216439 ! entry into host cell GO:0030260 32 12 1,000 4,297E-04 0,01202294 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! histone acetylation GO:0016573 26 12 1,000 4,297E-04 0,01188474 ! peptidyl-lysine modification GO:0018205 21 12 1,000 4,297E-04 0,01174969 ! negative regulation of mast cell proliferation GO:0070667 23 12 1,000 4,297E-04 0,01161767 GO:0042130|negative regulation of T cell proliferation, ! regulation of cyclin-dependent protein kinase activity GO:0000079 102 57 2,000 4,421E-04 0,01181961 ! positive regulation of cell migration GO:0030335 126 57 2,000 4,421E-04 0,01168973 ! regulation of intracellular transport GO:0032386 101 57 2,000 4,421E-04 0,01156266 ! establishment of organelle localization GO:0051656 109 59 2,000 4,894E-04 0,01266126 ! double-strand break repair via homologous recombination GO:0000724 19 13 1,000 5,07E-04 0,01297783 GO:0000725|recombinational repair, ! cellular carbohydrate catabolic process GO:0044275 15 13 1,000 5,07E-04 0,01284122 ! positive regulation of carbohydrate metabolic process GO:0045913 24 13 1,000 5,07E-04 0,01270746 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! regulation of monooxygenase activity GO:0032768 33 13 1,000 5,07E-04 0,01257645 ! regulation of fatty acid oxidation GO:0046320 27 13 1,000 5,07E-04 0,01244812 ! regulation of protein complex assembly GO:0043254 117 61 2,000 5,398E-04 0,01311862 ! response to peptide hormone stimulus GO:0043434 122 61 2,000 5,398E-04 0,01298744 ! N-terminal protein amino acid modification GO:0031365 27 14 1,000 5,905E-04 0,01406778 ! regulation of mRNA processing GO:0050684 24 14 1,000 5,905E-04 0,01392986 ! bone mineralization GO:0030282 17 14 1,000 5,905E-04 0,01379462 ! cAMP biosynthetic process GO:0006171 23 14 1,000 5,905E-04 0,01366198 ! steroid hormone receptor signaling pathway GO:0030518 129 63 2,000 5,934E-04 0,01359717 ! positive regulation of cell motion GO:0051272 146 64 2,000 6,214E-04 0,01410507 ! myeloid cell differentiation GO:0030099 111 65 2,000 6,503E-04 0,01462217 ! cell projection assembly GO:0030031 120 66 2,000 6,8E-04 0,01514846 ! C21-steroid hormone biosynthetic process GO:0006700 23 15 1,000 6,803E-04 0,01501546 ! regulation of glucose metabolic process GO:0010906 28 16 1,000 7,761E-04 0,01697598 ! negative regulation of nucleocytoplasmic transport GO:0046823 32 16 1,000 7,761E-04 0,01682304 ! activation of MAPKK activity GO:0000186 35 16 1,000 7,761E-04 0,01667284 ! positive regulation of protein import into nucleus GO:0042307 30 16 1,000 7,761E-04 0,01652529 ! biomineral formation GO:0031214 20 16 1,000 7,761E-04 0,01638033 ! negative regulation of leukocyte proliferation GO:0070664 31 16 1,000 7,761E-04 0,01623789 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! limbic system development GO:0021761 36 17 1,000 8,781E-04 0,01821369 ! ventricular cardiac muscle morphogenesis GO:0055010 27 17 1,000 8,781E-04 0,01805801 ! organelle localization GO:0051640 136 74 2,000 9,491E-04 0,01935118 ! phosphoinositide phosphorylation GO:0046854 33 18 1,000 9,862E-04 0,01994032 ! protein amino acid ADP-ribosylation GO:0006471 33 18 1,000 9,862E-04 0,01977415 ! response to retinoic acid GO:0032526 26 18 1,000 9,862E-04 0,01961073 ! regulation of generation of precursor metabolites and energy GO:0043467 38 18 1,000 9,862E-04 0,01944999 ! steroid biosynthetic process GO:0006694 131 76 2,000 1,025E-03 0,02005819 ! regulation of catabolic process GO:0009894 161 76 2,000 1,025E-03 0,01989643 ! lipid phosphorylation GO:0046834 35 19 1,000 1,1E-03 0,02118091 ! response to vitamin A GO:0033189 27 19 1,000 1,1E-03 0,02101281 ! neuromuscular junction development GO:0007528 34 19 1,000 1,1E-03 0,02084735 ! protein oligomerization GO:0051259 139 78 2,000 1,106E-03 0,02078104 ! protein amino acid acetylation GO:0006473 39 20 1,000 1,221E-03 0,02276635 ! positive regulation of nucleocytoplasmic transport GO:0046824 35 20 1,000 1,221E-03 0,02259123 ! cAMP metabolic process GO:0046058 36 20 1,000 1,221E-03 0,02241878 ! response to vitamin GO:0033273 31 20 1,000 1,221E-03 0,02224894 ! regulation of carbohydrate metabolic process GO:0006109 38 20 1,000 1,221E-03 0,02208165 GO:0010675|regulation of cellular carbohydrate metabolic process, ! C21-steroid hormone metabolic process GO:0008207 33 20 1,000 1,221E-03 0,02191686 ! regulation of fatty acid metabolic process GO:0019217 38 20 1,000 1,221E-03 0,02175452 ! negative regulation of T cell activation GO:0050868 40 20 1,000 1,221E-03 0,02159456 ! cholesterol metabolic process GO:0008203 136 82 2,000 1,277E-03 0,02243488 ! cellular response to hormone stimulus GO:0032870 167 82 2,000 1,277E-03 0,02227231 ! cholesterol biosynthetic process GO:0006695 37 21 1,000 1,347E-03 0,02331338 ! regulation of vasoconstriction GO:0019229 39 21 1,000 1,347E-03 0,02314686 ! negative regulation of Wnt receptor signaling pathway GO:0030178 39 21 1,000 1,347E-03 0,02298269 ! negative regulation of intracellular transport GO:0032387 41 21 1,000 1,347E-03 0,02282084 ! positive regulation of protein catabolic process GO:0045732 38 22 1,000 1,479E-03 0,02488559 ! calcium-independent cell-cell adhesion GO:0016338 30 22 1,000 1,479E-03 0,02471278 ! cardiac muscle tissue morphogenesis GO:0055008 33 22 1,000 1,479E-03 0,02454234 GO:0060415|muscle tissue morphogenesis, ! positive regulation of intracellular transport GO:0032388 37 22 1,000 1,479E-03 0,02437425 ! positive regulation of B cell activation GO:0050871 38 22 1,000 1,479E-03 0,02420844 ! regulation of protein transport GO:0051223 154 87 2,000 1,515E-03 0,02462655 GO:0070201|regulation of establishment of protein localization, ! positive regulation of DNA replication GO:0045740 43 23 1,000 1,617E-03 0,02611426 ! positive regulation of cell adhesion GO:0045785 56 23 1,000 1,617E-03 0,02594017 ! viral genome replication GO:0019079 41 23 1,000 1,617E-03 0,02576838 ! sex determination GO:0007530 47 23 1,000 1,617E-03 0,02559885 ! ossification GO:0001503 188 90 2,000 1,67E-03 0,02625654 ! bone development GO:0060348 189 91 2,000 1,723E-03 0,0269254 ! sterol metabolic process GO:0016125 152 91 2,000 1,723E-03 0,02675168 ! positive regulation of fibroblast proliferation GO:0048146 43 24 1,000 1,761E-03 0,02716437 ! regulation of cellular catabolic process GO:0031329 52 24 1,000 1,761E-03 0,02699135 ! negative regulation of phosphorylation GO:0042326 47 24 1,000 1,761E-03 0,02682051 ! pallium development GO:0021543 49 24 1,000 1,761E-03 0,02665183 ! regulation of oxidoreductase activity GO:0051341 46 24 1,000 1,761E-03 0,02648526 ! protein tetramerization GO:0051262 52 24 1,000 1,761E-03 0,02632075 ! G2/M transition of mitotic cell cycle GO:0000086 43 25 1,000 1,911E-03 0,02838527 ! myelination GO:0042552 45 25 1,000 1,911E-03 0,02821113 ! phototransduction GO:0007602 33 25 1,000 1,911E-03 0,02803911 ! protein amino acid alkylation GO:0008213 53 25 1,000 1,911E-03 0,02786918 GO:0006479|protein amino acid methylation, ! negative regulation of cell development GO:0010721 73 25 1,000 1,911E-03 0,02770129 GO:0050768|negative regulation of neurogenesis, ! somitogenesis GO:0001756 43 25 1,000 1,911E-03 0,02753541 ! forebrain development GO:0030900 188 95 2,000 1,949E-03 0,02791358 ! leukocyte differentiation GO:0002521 202 96 2,000 2,008E-03 0,02859052 ! initiation of viral infection GO:0019059 57 26 1,000 2,067E-03 0,02925453 ! regulation of transcription factor import into nucleus GO:0042990 54 26 1,000 2,067E-03 0,02908345 ! peptidyl-tyrosine phosphorylation GO:0018108 48 26 1,000 2,067E-03 0,02891436 ! negative regulation of phosphorus metabolic process GO:0010563 51 26 1,000 2,067E-03 0,02874723 GO:0045936|negative regulation of phosphate metabolic process, ! regulation of cellular ketone metabolic process GO:0010565 44 26 1,000 2,067E-03 0,02858201 ! regulation of protein localization GO:0032880 176 97 2,000 2,068E-03 0,02843873 ! skeletal muscle tissue development GO:0007519 186 99 2,000 2,192E-03 0,02997048 GO:0060538|skeletal muscle organ development, ! regulation of fibroblast proliferation GO:0048145 52 27 1,000 2,229E-03 0,03029455 ! epidermal growth factor receptor signaling pathway GO:0007173 61 27 1,000 2,229E-03 0,03012436 ! protein amino acid acylation GO:0043543 55 27 1,000 2,229E-03 0,02995606 ! cyclic nucleotide biosynthetic process GO:0009190 41 27 1,000 2,229E-03 0,02978964 ! negative regulation of neuron differentiation GO:0045665 42 27 1,000 2,229E-03 0,02962506 ! negative regulation of lymphocyte activation GO:0051250 53 27 1,000 2,229E-03 0,02946228 ! cell cycle arrest GO:0007050 213 100 2,000 2,256E-03 0,02966057 ! detection of light stimulus involved in sensory perception GO:0050962 36 28 1,000 2,396E-03 0,03133118 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! peptidyl-tyrosine modification GO:0018212 50 28 1,000 2,396E-03 0,03116182 ! sterol biosynthetic process GO:0016126 52 29 1,000 2,569E-03 0,03323442 ! detection of light stimulus GO:0009583 38 29 1,000 2,569E-03 0,0330567 ! cellular response to extracellular stimulus GO:0031668 48 29 1,000 2,569E-03 0,03288087 ! tissue homeostasis GO:0001894 48 29 1,000 2,569E-03 0,03270689 GO:0048871|multicellular organismal homeostasis, ! ensheathment of neurons GO:0007272 57 30 1,000 2,748E-03 0,03480031 GO:0008366|axon ensheathment, ! negative regulation of leukocyte activation GO:0002695 56 30 1,000 2,748E-03 0,03461811 ! regulation of B cell activation GO:0050864 50 30 1,000 2,748E-03 0,03443781 ! response to heat GO:0009408 50 30 1,000 2,748E-03 0,03425937 ! regulation of protein import into nucleus GO:0042306 63 32 1,000 3,123E-03 0,03873224 ! peripheral nervous system development GO:0007422 64 32 1,000 3,123E-03 0,03853362 ! negative regulation of protein transport GO:0051224 69 33 1,000 3,319E-03 0,0407421 ! telencephalon development GO:0021537 68 35 1,000 3,728E-03 0,04552629 ! calcium-mediated signaling GO:0019722 62 35 1,000 3,728E-03 0,04529636 ! regulation of Wnt receptor signaling pathway GO:0030111 71 36 1,000 3,94E-03 0,04764006 ! hormone biosynthetic process GO:0042446 57 36 1,000 3,94E-03 0,04740186 ! negative regulation of cell activation GO:0050866 65 36 1,000 3,94E-03 0,04716603 ! cyclic nucleotide metabolic process GO:0009187 63 37 1,000 4,159E-03 0,04953145 ! positive regulation of DNA metabolic process GO:0051054 72 38 1,000 4,382E-03 0,05193869 ! carbohydrate homeostasis GO:0033500 53 38 1,000 4,382E-03 0,05168409 GO:0042593|glucose homeostasis, ! positive regulation of leukocyte proliferation GO:0070665 62 38 1,000 4,382E-03 0,05143197 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! mammary gland development GO:0030879 86 39 1,000 4,611E-03 0,05385876 ! learning GO:0007612 77 39 1,000 4,611E-03 0,05359857 ! segmentation GO:0035282 67 39 1,000 4,611E-03 0,05334088 ! regulation of action potential in neuron GO:0019228 73 39 1,000 4,611E-03 0,05308566 ! regulation of T cell proliferation GO:0042129 71 41 1,000 5,086E-03 0,05827035 ! regulation of T cell differentiation GO:0045580 70 41 1,000 5,086E-03 0,05799418 ! positive regulation of transcription factor activity GO:0051091 62 42 1,000 5,331E-03 0,06050544 GO:0090047|positive regulation of transcription regulator activity, ! striated muscle cell differentiation GO:0051146 82 43 1,000 5,582E-03 0,06305354 ! double-strand break repair GO:0006302 81 44 1,000 5,838E-03 0,06563765 ! biopolymer methylation GO:0043414 84 44 1,000 5,838E-03 0,06533236 ! detection of stimulus involved in sensory perception GO:0050906 66 45 1,000 6,099E-03 0,06794094 ! induction of apoptosis by intracellular signals GO:0008629 93 45 1,000 6,099E-03 0,06762785 ! regulation of gene-specific transcription GO:0032583 96 46 1,000 6,366E-03 0,07026008 ! positive regulation of protein transport GO:0051222 72 46 1,000 6,366E-03 0,06993925 ! positive regulation of DNA binding GO:0043388 73 47 1,000 6,638E-03 0,0725943 ! methylation GO:0032259 90 47 1,000 6,638E-03 0,07226582 ! protein homooligomerization GO:0051260 76 47 1,000 6,638E-03 0,0719403 ! positive regulation of cell cycle GO:0045787 89 48 1,000 6,915E-03 0,07460684 ! regulation of lymphocyte differentiation GO:0045619 81 48 1,000 6,915E-03 0,07427377 ! regulation of action potential GO:0001508 95 49 1,000 7,197E-03 0,07696163 ! response to temperature stimulus GO:0009266 76 49 1,000 7,197E-03 0,07662109 ! detection of abiotic stimulus GO:0009582 74 49 1,000 7,197E-03 0,07628355 ! histone modification GO:0016570 91 50 1,000 7,485E-03 0,07898159 ! negative regulation of immune system process GO:0002683 95 50 1,000 7,485E-03 0,07863669 ! positive regulation of binding GO:0051099 78 51 1,000 7,777E-03 0,08135463 ! chromatin remodeling GO:0006338 109 51 1,000 7,777E-03 0,08100245 ! regulation of angiogenesis GO:0045765 114 52 1,000 8,075E-03 0,08373961 ! positive regulation of growth GO:0045927 90 52 1,000 8,075E-03 0,08338021 ! covalent chromatin modification GO:0016569 101 52 1,000 8,075E-03 0,08302389 ! amino acid activation GO:0043038 92 52 1,000 8,075E-03 0,08267059 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! synapse organization GO:0050808 85 52 1,000 8,075E-03 0,08232029 ! regulation of translational initiation GO:0006446 82 53 1,000 8,377E-03 0,0850456 ! nucleoside monophosphate biosynthetic process GO:0009124 85 53 1,000 8,377E-03 0,08468827 ! activation of phospholipase C activity GO:0007202 103 54 1,000 8,685E-03 0,0874316 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of phospholipase activity GO:0010518 104 55 1,000 8,998E-03 0,09020234 ! regulation of protein catabolic process GO:0042176 116 55 1,000 8,998E-03 0,08982806 ! skeletal muscle fiber development GO:0048741 111 56 1,000 9,315E-03 0,09261556 ! regulation of DNA replication GO:0006275 101 56 1,000 9,315E-03 0,09223443 ! muscle fiber development GO:0048747 112 57 1,000 9,638E-03 0,09503811 ! lipid modification GO:0030258 97 57 1,000 9,638E-03 0,0946502 ! regulation of phospholipase activity GO:0010517 106 57 1,000 9,638E-03 0,09426545 ! positive regulation of lipase activity GO:0060193 108 58 1,000 9,966E-03 0,0970749 ! tRNA processing GO:0008033 89 61 1,000 0,01097782 0,10650259 ! nucleoside monophosphate metabolic process GO:0009123 107 63 1,000 0,01167673 0,11282816 ! detection of external stimulus GO:0009581 91 63 1,000 0,01167673 0,11237684 ! embryonic limb morphogenesis GO:0030326 125 65 1,000 0,01239472 0,11881154 GO:0035113|embryonic appendage morphogenesis, ! fatty acid biosynthetic process GO:0006633 124 66 1,000 0,01276081 0,12183531 ! negative regulation of protein ubiquitination GO:0031397 9 5 0,000 0,01288345 0,12252004 ! negative regulation of nucleotide biosynthetic process GO:0030809 9 5 0,000 0,01288345 0,12203768 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! positive regulation of interferon-alpha biosynthetic process GO:0045356 7 5 0,000 0,01288345 0,1215591 ! positive regulation of helicase activity GO:0051096 11 5 0,000 0,01288345 0,12108426 ! neuron fate determination GO:0048664 7 5 0,000 0,01288345 0,12061312 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,01288345 0,12014562 ! regulation of cGMP biosynthetic process GO:0030826 9 5 0,000 0,01288345 0,11968174 ! hemoglobin biosynthetic process GO:0042541 7 5 0,000 0,01288345 0,11922143 ! polyol transport GO:0015791 12 5 0,000 0,01288345 0,11876464 ! post-embryonic morphogenesis GO:0009886 8 5 0,000 0,01288345 0,11831134 ! benzene and derivative metabolic process GO:0042537 12 5 0,000 0,01288345 0,11786149 ! response to superoxide GO:0000303 10 5 0,000 0,01288345 0,11741504 ! negative regulation of bone resorption GO:0045779 10 5 0,000 0,01288345 0,11697196 ! positive regulation of lipid biosynthetic process GO:0046889 9 5 0,000 0,01288345 0,11653222 GO:0045940|positive regulation of steroid metabolic process, ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 7 5 0,000 0,01288345 0,11609577 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! tongue development GO:0043586 8 5 0,000 0,01288345 0,11566258 ! female meiosis GO:0007143 7 5 0,000 0,01288345 0,1152326 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,01288345 0,11480582 ! phenylalanyl-tRNA aminoacylation GO:0006432 7 5 0,000 0,01288345 0,11438218 ! cobalt ion transport GO:0006824 11 5 0,000 0,01288345 0,11396166 ! cellular sodium ion homeostasis GO:0006883 10 5 0,000 0,01288345 0,11354421 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 15 5 0,000 0,01288345 0,11312982 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 10 5 0,000 0,01288345 0,11271844 ! nuclear mRNA 3'-splice site recognition GO:0000389 7 5 0,000 0,01288345 0,11231004 ! phospholipid dephosphorylation GO:0046839 12 5 0,000 0,01288345 0,11190459 ! regulation of cardiac muscle cell proliferation GO:0060043 8 5 0,000 0,01288345 0,11150205 ! embryonic camera-type eye development GO:0031076 10 5 0,000 0,01288345 0,1111024 GO:0048596|embryonic camera-type eye morphogenesis, ! selenocysteine incorporation GO:0001514 12 5 0,000 0,01288345 0,11070561 GO:0006451|translational readthrough, ! negative regulation of cell-cell adhesion GO:0022408 12 5 0,000 0,01288345 0,11031164 ! positive regulation of cell-cell adhesion GO:0022409 14 5 0,000 0,01288345 0,10992046 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,01288345 0,10953205 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,01288345 0,10914638 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,01288345 0,10876341 ! regulation of mitochondrial membrane permeability GO:0046902 14 5 0,000 0,01288345 0,10838311 ! negative chemotaxis GO:0050919 14 5 0,000 0,01288345 0,10800547 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,01288345 0,10763045 ! transcription from mitochondrial promoter GO:0006390 7 5 0,000 0,01288345 0,10725803 ! sensory perception of bitter taste GO:0050913 7 5 0,000 0,01288345 0,10688817 ! behavioral response to pain GO:0048266 9 5 0,000 0,01288345 0,10652086 ! clathrin coat assembly GO:0048268 14 5 0,000 0,01288345 0,10615606 ! Notch receptor processing GO:0007220 8 5 0,000 0,01288345 0,10579376 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,01288345 0,10543391 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,01288345 0,10507651 ! micturition GO:0060073 9 5 0,000 0,01288345 0,10472152 ! serotonin receptor signaling pathway GO:0007210 10 5 0,000 0,01288345 0,10436892 ! copulation GO:0007620 9 5 0,000 0,01288345 0,10401869 ! glial cell fate commitment GO:0021781 13 5 0,000 0,01288345 0,1036708 ! protein maturation by protein folding GO:0022417 13 5 0,000 0,01288345 0,10332524 ! spermidine metabolic process GO:0008216 7 5 0,000 0,01288345 0,10298196 ! regulation of potassium ion transport GO:0043266 10 5 0,000 0,01288345 0,10264096 ! cell migration involved in gastrulation GO:0042074 7 5 0,000 0,01288345 0,10230221 ! apoptotic cell clearance GO:0043277 20 5 0,000 0,01288345 0,10196569 ! positive regulation of muscle cell differentiation GO:0051149 13 5 0,000 0,01288345 0,10163138 ! lipoprotein particle clearance GO:0034381 10 5 0,000 0,01288345 0,10129925 ! grooming behavior GO:0007625 6 5 0,000 0,01288345 0,10096929 ! fructose 1,6-bisphosphate metabolic process GO:0030388 7 5 0,000 0,01288345 0,10064146 ! regulation of odontogenesis of dentine-containing tooth GO:0042487 11 5 0,000 0,01288345 0,10031576 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,01288345 0,09999216 ! response to protozoan GO:0001562 10 5 0,000 0,01288345 0,09967065 ! lymph vessel development GO:0001945 10 5 0,000 0,01288345 0,09935119 ! regulation of activin receptor signaling pathway GO:0032925 14 5 0,000 0,01288345 0,09903377 ! endochondral ossification GO:0001958 16 5 0,000 0,01288345 0,09871838 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 11 5 0,000 0,01288345 0,09840499 ! parathyroid gland development GO:0060017 13 5 0,000 0,01288345 0,09809358 ! anagen GO:0042640 6 5 0,000 0,01288345 0,09778413 ! deoxyribonucleoside triphosphate metabolic process GO:0009200 6 5 0,000 0,01288345 0,09747664 ! positive regulation of viral genome replication GO:0045070 9 5 0,000 0,01288345 0,09717107 ! traversing start control point of mitotic cell cycle GO:0007089 12 5 0,000 0,01288345 0,09686741 ! hydrogen peroxide biosynthetic process GO:0050665 7 5 0,000 0,01288345 0,09656564 ! dorsal spinal cord development GO:0021516 7 5 0,000 0,01288345 0,09626575 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 12 5 0,000 0,01288345 0,09596771 ! sphingoid catabolic process GO:0046521 6 5 0,000 0,01288345 0,09567151 ! skeletal myofibril assembly GO:0014866 10 5 0,000 0,01288345 0,09537714 ! smooth muscle tissue development GO:0048745 28 5 0,000 0,01288345 0,09508457 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 7 5 0,000 0,01288345 0,09479379 ! peptidyl-lysine modification to hypusine GO:0008612 10 5 0,000 0,01288345 0,09450479 GO:0046516|hypusine metabolic process, ! epithelial cell proliferation GO:0050673 9 5 0,000 0,01288345 0,09421754 ! cardiac muscle fiber development GO:0048739 10 5 0,000 0,01288345 0,09393203 ! transepithelial chloride transport GO:0030321 9 5 0,000 0,01288345 0,09364825 GO:0070633|transepithelial transport, ! thiamin diphosphate biosynthetic process GO:0009229 5 5 0,000 0,01288345 0,09336618 GO:0042724|thiamin and derivative biosynthetic process, GO:0042357|thiamin diphosphate metabolic process, ! regulation of retroviral genome replication GO:0045091 7 5 0,000 0,01288345 0,0930858 ! negative regulation of survival gene product expression GO:0008634 8 5 0,000 0,01288345 0,0928071 ! neutrophil mediated immunity GO:0002446 7 5 0,000 0,01288345 0,09253006 ! negative regulation of oligodendrocyte differentiation GO:0048715 15 5 0,000 0,01288345 0,09225467 ! histidine catabolic process GO:0006548 6 5 0,000 0,01288345 0,09198092 GO:0009077|histidine family amino acid catabolic process, ! glycine biosynthetic process GO:0006545 7 5 0,000 0,01288345 0,09170879 ! microvillus organization GO:0032528 7 5 0,000 0,01288345 0,09143826 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 10 5 0,000 0,01288345 0,09116933 ! L-serine biosynthetic process GO:0006564 6 5 0,000 0,01288345 0,09090197 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,01288345 0,09063617 ! tryptophan metabolic process GO:0006568 9 5 0,000 0,01288345 0,09037193 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 17 5 0,000 0,01288345 0,09010922 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,01288345 0,08984803 ! immunoglobulin V(D)J recombination GO:0033152 21 5 0,000 0,01288345 0,08958835 ! polyol catabolic process GO:0046174 7 5 0,000 0,01288345 0,08933017 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,01288345 0,08907348 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,01288345 0,08881825 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,01288345 0,08856449 ! muscle cell migration GO:0014812 8 5 0,000 0,01288345 0,08831217 ! mitochondrial fission GO:0000266 8 5 0,000 0,01288345 0,08806128 ! sister chromatid cohesion GO:0007062 12 5 0,000 0,01288345 0,08781181 ! mRNA transcription GO:0009299 9 5 0,000 0,01288345 0,08756376 ! peptidoglycan metabolic process GO:0000270 5 5 0,000 0,01288345 0,0873171 GO:0009253|peptidoglycan catabolic process, ! nerve growth factor processing GO:0032455 8 5 0,000 0,01288345 0,08707183 ! positive regulation of filopodium assembly GO:0051491 14 5 0,000 0,01288345 0,08682793 GO:0051489|regulation of filopodium assembly, ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,01288345 0,08658539 ! regulation of retinoic acid receptor signaling pathway GO:0048385 12 5 0,000 0,01288345 0,08634421 ! regulation of angiotensin levels in blood GO:0002002 9 5 0,000 0,01288345 0,08610436 GO:0060177|regulation of angiotensin metabolic process, ! regulation of response to food GO:0032095 7 5 0,000 0,01288345 0,08586585 ! response to food GO:0032094 6 5 0,000 0,01288345 0,08562865 ! morphogenesis of an epithelial sheet GO:0002011 11 5 0,000 0,01288345 0,08539276 ! positive regulation of transporter activity GO:0032411 8 5 0,000 0,01288345 0,08515816 GO:0032414|positive regulation of ion transmembrane transporter activity, ! regulation of glycogen metabolic process GO:0070873 11 5 0,000 0,01288345 0,08492485 GO:0032881|regulation of polysaccharide metabolic process, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,01288345 0,08469282 ! paraxial mesoderm development GO:0048339 14 5 0,000 0,01288345 0,08446205 ! forebrain neuron development GO:0021884 13 5 0,000 0,01288345 0,08423253 ! lipoprotein catabolic process GO:0042159 11 5 0,000 0,01288345 0,08400426 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 9 5 0,000 0,01288345 0,08377722 ! substrate-bound cell migration, cell extension GO:0006930 6 5 0,000 0,01288345 0,0835514 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,01288345 0,0833268 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 20 5 0,000 0,01288345 0,08310341 ! peptidyl-histidine phosphorylation GO:0018106 9 5 0,000 0,01288345 0,0828812 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,01288345 0,08266019 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 10 5 0,000 0,01288345 0,08244035 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 7 5 0,000 0,01288345 0,08222167 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,01288345 0,08200416 ! positive regulation of fatty acid metabolic process GO:0045923 11 5 0,000 0,01288345 0,08178779 ! basic amino acid transport GO:0015802 11 5 0,000 0,01288345 0,08157255 ! cellular glucose homeostasis GO:0001678 5 5 0,000 0,01288345 0,08135845 ! early endosome to late endosome transport GO:0045022 12 5 0,000 0,01288345 0,08114547 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 0,000 0,01288345 0,0809336 ! depyrimidination GO:0045008 10 5 0,000 0,01288345 0,08072284 ! regulation of synaptic growth at neuromuscular junction GO:0008582 9 5 0,000 0,01288345 0,08051317 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,01288345 0,08030459 ! homeostasis of number of cells within a tissue GO:0048873 12 5 0,000 0,01288345 0,08009708 ! zinc ion homeostasis GO:0055069 8 5 0,000 0,01288345 0,07989065 GO:0006882|cellular zinc ion homeostasis, ! meiotic chromosome segregation GO:0045132 7 5 0,000 0,01288345 0,07968527 ! nucleoside monophosphate catabolic process GO:0009125 11 5 0,000 0,01288345 0,07948095 ! forebrain morphogenesis GO:0048853 13 5 0,000 0,01288345 0,07927767 ! leukemia inhibitory factor signaling pathway GO:0048861 14 5 0,000 0,01288345 0,07907544 ! negative regulation of alpha-beta T cell activation GO:0046636 10 5 0,000 0,01288345 0,07887423 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 10 5 0,000 0,01288345 0,07867404 ! peptidyl-arginine modification GO:0018195 9 5 0,000 0,01288345 0,07847486 ! DNA damage response, detection of DNA damage GO:0042769 5 5 0,000 0,01288345 0,07827669 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,01288345 0,07807952 ! response to arsenic GO:0046685 10 5 0,000 0,01288345 0,07788334 ! negative regulation of T cell mediated immunity GO:0002710 12 5 0,000 0,01288345 0,07768815 GO:0002707|negative regulation of lymphocyte mediated immunity, ! mast cell degranulation GO:0043303 7 5 0,000 0,01288345 0,07749393 GO:0002448|mast cell mediated immunity, ! regulation of leukocyte degranulation GO:0043300 7 5 0,000 0,01288345 0,07730067 ! base-excision repair, DNA ligation GO:0006288 7 5 0,000 0,01288345 0,07710838 ! response to cadmium ion GO:0046686 7 5 0,000 0,01288345 0,07691705 ! bile acid biosynthetic process GO:0006699 6 5 0,000 0,01288345 0,07672666 ! sphingomyelin catabolic process GO:0006685 5 5 0,000 0,01288345 0,07653721 ! glucosylceramide metabolic process GO:0006678 6 5 0,000 0,01288345 0,0763487 ! decidualization GO:0046697 11 5 0,000 0,01288345 0,07616111 ! platelet activating factor biosynthetic process GO:0006663 6 5 0,000 0,01288345 0,07597444 ! CD4-positive, alpha beta T cell differentiation GO:0043367 8 5 0,000 0,01288345 0,07578868 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,01288345 0,07560383 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,01288345 0,07541988 GO:0032754|positive regulation of interleukin-5 production, ! protein autoprocessing GO:0016540 7 5 0,000 0,01288345 0,07523682 ! base conversion or substitution editing GO:0016553 5 5 0,000 0,01288345 0,07505465 ! neural tube patterning GO:0021532 7 5 0,000 0,01288345 0,07487336 ! embryonic cleavage GO:0040016 6 5 0,000 0,01288345 0,07469294 ! peroxisome fission GO:0016559 5 5 0,000 0,01288345 0,07451339 ! histone demethylation GO:0016577 10 5 0,000 0,01288345 0,0743347 ! reproductive behavior in a multicellular organism GO:0033057 14 5 0,000 0,01288345 0,07415687 ! mitotic recombination GO:0006312 9 5 0,000 0,01288345 0,07397988 ! negative regulation of interleukin-6 production GO:0032715 5 5 0,000 0,01288345 0,07380374 ! metaphase plate congression GO:0051310 7 5 0,000 0,01288345 0,07362843 ! regulation of sterol transport GO:0032371 7 5 0,000 0,01288345 0,07345396 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 8 5 0,000 0,01288345 0,07328031 ! enteric nervous system development GO:0048484 8 5 0,000 0,01288345 0,07310748 ! indolalkylamine biosynthetic process GO:0046219 7 5 0,000 0,01288345 0,07293546 GO:0042435|indole derivative biosynthetic process, GO:0030187|melatonin biosynthetic process, ! lymphocyte costimulation GO:0031294 6 5 0,000 0,01288345 0,07276425 GO:0031295|T cell costimulation, ! positive regulation of mast cell activation GO:0033005 11 5 0,000 0,01288345 0,07259384 ! skeletal muscle regeneration GO:0043403 8 5 0,000 0,01288345 0,07242423 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 14 5 0,000 0,01288345 0,07225541 ! plasminogen activation GO:0031639 5 5 0,000 0,01288345 0,07208737 ! B cell homeostasis GO:0001782 13 5 0,000 0,01288345 0,07192012 ! positive regulation of Wnt receptor signaling pathway GO:0030177 11 5 0,000 0,01288345 0,07175364 ! coenzyme A biosynthetic process GO:0015937 7 5 0,000 0,01288345 0,07158792 ! metaphase GO:0051323 8 5 0,000 0,01288345 0,07142297 ! positive regulation of blood coagulation GO:0030194 11 5 0,000 0,01288345 0,07125878 ! cellular response to nutrient GO:0031670 8 5 0,000 0,01288345 0,07109535 ! positive regulation of macrophage activation GO:0043032 12 5 0,000 0,01288345 0,07093266 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,01288345 0,07077071 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,01288345 0,0706095 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 10 5 0,000 0,01288345 0,07044902 GO:0042634|regulation of hair cycle, ! definitive hemopoiesis GO:0060216 13 5 0,000 0,01288345 0,07028928 ! response to redox state GO:0051775 5 5 0,000 0,01288345 0,07013025 GO:0006980|redox signal response, ! negative regulation of macrophage differentiation GO:0045650 6 5 0,000 0,01288345 0,06997194 ! regulation of hydrogen peroxide metabolic process GO:0010310 6 5 0,000 0,01288345 0,06981435 ! regulation of keratinocyte differentiation GO:0045616 6 5 0,000 0,01288345 0,06965746 ! regulation of telomerase activity GO:0051972 6 5 0,000 0,01288345 0,06950128 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,01288345 0,0693458 GO:0006681|galactosylceramide metabolic process, ! secretory granule organization GO:0033363 11 5 0,000 0,01288345 0,06919101 ! porphyrin catabolic process GO:0006787 12 5 0,000 0,01288345 0,06903691 GO:0033015|tetrapyrrole catabolic process, ! circadian behavior GO:0048512 13 5 0,000 0,01288345 0,06888349 ! striatum development GO:0021756 9 5 0,000 0,01288345 0,06873076 ! positive regulation of T cell mediated cytotoxicity GO:0001916 13 5 0,000 0,01288345 0,0685787 ! activation of Ras GTPase activity GO:0032856 10 5 0,000 0,01288345 0,06842731 GO:0032862|activation of Rho GTPase activity, ! triglyceride biosynthetic process GO:0019432 7 5 0,000 0,01288345 0,06827659 ! glial cell migration GO:0008347 11 5 0,000 0,01288345 0,06812653 ! inner cell mass cell proliferation GO:0001833 5 5 0,000 0,01288345 0,06797713 ! regulation of mitochondrial depolarization GO:0051900 13 5 0,000 0,01288345 0,06782838 ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,01288345 0,06768029 ! somatic stem cell maintenance GO:0035019 15 5 0,000 0,01288345 0,06753283 ! negative regulation of fibrinolysis GO:0051918 11 5 0,000 0,01288345 0,06738602 ! negative regulation of lipase activity GO:0060192 8 5 0,000 0,01288345 0,06723985 ! neuroprotection GO:0043526 6 5 0,000 0,01288345 0,06709431 ! neural plate development GO:0001840 8 5 0,000 0,01288345 0,0669494 ! positive regulation of blood vessel endothelial cell migration GO:0043536 16 5 0,000 0,01288345 0,06680511 ! regulation of sensory perception GO:0051931 7 5 0,000 0,01288345 0,06666144 GO:0051930|regulation of sensory perception of pain, ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 10 5 0,000 0,01288345 0,06651839 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 14 5 0,000 0,01288345 0,06637595 ! positive regulation of actin filament bundle formation GO:0032233 17 5 0,000 0,01288345 0,06623413 ! negative regulation of actin filament bundle formation GO:0032232 14 5 0,000 0,01288345 0,0660929 GO:0051497|negative regulation of stress fiber formation, ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 17 5 0,000 0,01288345 0,06595228 ! sequestering of calcium ion GO:0051208 7 5 0,000 0,01288345 0,06581225 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,01288345 0,06567282 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! retrograde protein transport, ER to cytosol GO:0030970 8 5 0,000 0,01288345 0,06553398 ! spindle assembly GO:0051225 6 5 0,000 0,01288345 0,06539572 ! metallo-sulfur cluster assembly GO:0031163 5 5 0,000 0,01288345 0,06525804 GO:0016226|iron-sulfur cluster assembly, ! ensheathment of axons in the peripheral nervous system GO:0032292 14 5 0,000 0,01288345 0,06512095 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 7 5 0,000 0,01288345 0,06498442 ! drug metabolic process GO:0017144 6 5 0,000 0,01288345 0,06484847 ! stem cell division GO:0017145 11 5 0,000 0,01288345 0,06471309 GO:0048103|somatic stem cell division, ! phospholipid scrambling GO:0017121 8 5 0,000 0,01288345 0,06457827 ! organ regeneration GO:0031100 7 5 0,000 0,01288345 0,06444401 ! carnitine metabolic process GO:0009437 7 5 0,000 0,01288345 0,06431031 GO:0006577|betaine metabolic process, ! cellular anion homeostasis GO:0030002 9 5 0,000 0,01288345 0,06417716 GO:0055081|anion homeostasis, ! regulation of liquid surface tension GO:0050828 10 5 0,000 0,01288345 0,06404457 ! cellular hormone metabolic process GO:0034754 113 67 1,000 0,01313158 0,06514348 ! negative regulation of cell growth GO:0030308 132 67 1,000 0,01313158 0,06500944 ! activation of MAPK activity GO:0000187 115 67 1,000 0,01313158 0,06487595 ! lung development GO:0030324 144 67 1,000 0,01313158 0,06474301 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 114 67 1,000 0,01313158 0,06461061 ! regulation of lipase activity GO:0060191 130 68 1,000 0,01350703 0,06632226 ! negative regulation of cell size GO:0045792 134 69 1,000 0,01388711 0,06804967 ! appendage morphogenesis GO:0035107 135 70 1,000 0,01427181 0,06979262 GO:0035108|limb morphogenesis, ! respiratory tube development GO:0030323 150 70 1,000 0,01427181 0,06965105 ! appendage development GO:0048736 136 71 1,000 0,01466109 0,07140605 GO:0060173|limb development, ! regulation of caspase activity GO:0043281 122 72 1,000 0,01505494 0,07317614 ! phosphoinositide metabolic process GO:0030384 128 72 1,000 0,01505494 0,0730286 ! respiratory system development GO:0060541 153 72 1,000 0,01505494 0,07288166 ! regulation of interferon-alpha biosynthetic process GO:0045354 8 6 0,000 0,0154404 0,07459761 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 7 6 0,000 0,0154404 0,07444811 ! negative regulation of S phase of mitotic cell cycle GO:0045749 11 6 0,000 0,0154404 0,07429922 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,0154404 0,07415092 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 9 6 0,000 0,0154404 0,07400321 ! oligosaccharide biosynthetic process GO:0009312 10 6 0,000 0,0154404 0,07385608 ! regulation of cGMP metabolic process GO:0030823 11 6 0,000 0,0154404 0,07370954 ! positive regulation of actin filament polymerization GO:0030838 11 6 0,000 0,0154404 0,07356358 ! sleep GO:0030431 13 6 0,000 0,0154404 0,0734182 ! response to oxygen radical GO:0000305 11 6 0,000 0,0154404 0,07327339 ! positive regulation of axon extension GO:0045773 11 6 0,000 0,0154404 0,07312915 ! myoblast cell fate commitment GO:0048625 16 6 0,000 0,0154404 0,07298548 ! negative regulation of small GTPase mediated signal transduction GO:0051058 17 6 0,000 0,0154404 0,07284237 GO:0046580|negative regulation of Ras protein signal transduction, ! pyrimidine nucleotide-sugar transport GO:0015781 11 6 0,000 0,0154404 0,07269982 ! regulation of interferon-beta production GO:0032648 8 6 0,000 0,0154404 0,07255783 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 10 6 0,000 0,0154404 0,07241639 ! virion attachment to host cell surface receptor GO:0019062 15 6 0,000 0,0154404 0,0722755 ! forebrain regionalization GO:0021871 8 6 0,000 0,0154404 0,07213516 ! DNA catabolic process, exonucleolytic GO:0000738 8 6 0,000 0,0154404 0,07199537 ! male meiosis GO:0007140 7 6 0,000 0,0154404 0,07185611 ! short-chain fatty acid metabolic process GO:0046459 8 6 0,000 0,0154404 0,07171739 ! response to zinc ion GO:0010043 9 6 0,000 0,0154404 0,07157921 ! transforming growth factor beta receptor complex assembly GO:0007181 7 6 0,000 0,0154404 0,07144156 ! regulation of respiratory gaseous exchange GO:0043576 8 6 0,000 0,0154404 0,07130443 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8 6 0,000 0,0154404 0,07116783 ! neurofilament cytoskeleton organization GO:0060052 12 6 0,000 0,0154404 0,07103176 ! malate metabolic process GO:0006108 11 6 0,000 0,0154404 0,0708962 ! posttranscriptional gene silencing by RNA GO:0035194 19 6 0,000 0,0154404 0,07076116 GO:0016441|posttranscriptional gene silencing, ! phototransduction, visible light GO:0007603 9 6 0,000 0,0154404 0,07062663 ! protein refolding GO:0042026 15 6 0,000 0,0154404 0,07049262 ! cerebral cortex radially oriented cell migration GO:0021799 11 6 0,000 0,0154404 0,07035911 ! opsonization GO:0008228 8 6 0,000 0,0154404 0,0702261 ! mating behavior GO:0007617 7 6 0,000 0,0154404 0,0700936 ! neuron remodeling GO:0016322 15 6 0,000 0,0154404 0,0699616 ! erythrocyte maturation GO:0043249 7 6 0,000 0,0154404 0,06983009 ! embryonic hemopoiesis GO:0035162 14 6 0,000 0,0154404 0,06969908 ! equilibrioception GO:0050957 14 6 0,000 0,0154404 0,06956856 ! protein amino acid dealkylation GO:0008214 12 6 0,000 0,0154404 0,06943852 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 9 6 0,000 0,0154404 0,06930897 ! photoreceptor cell development GO:0042461 10 6 0,000 0,0154404 0,06917991 GO:0046530|photoreceptor cell differentiation, ! regulation of smooth muscle cell differentiation GO:0051150 9 6 0,000 0,0154404 0,06905132 ! ovulation from ovarian follicle GO:0001542 8 6 0,000 0,0154404 0,06892321 ! response to interferon-gamma GO:0034341 15 6 0,000 0,0154404 0,06879557 ! toxin metabolic process GO:0009404 11 6 0,000 0,0154404 0,06866841 ! regulation of interleukin-12 biosynthetic process GO:0045075 7 6 0,000 0,0154404 0,06854171 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,0154404 0,06841549 ! spinal cord dorsal/ventral patterning GO:0021513 12 6 0,000 0,0154404 0,06828972 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 12 6 0,000 0,0154404 0,06816442 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, ! cGMP-mediated signaling GO:0019934 13 6 0,000 0,0154404 0,06803958 ! dermatan sulfate proteoglycan metabolic process GO:0050655 13 6 0,000 0,0154404 0,06791519 ! thymic T cell selection GO:0045061 12 6 0,000 0,0154404 0,06779126 ! protein lipoylation GO:0009249 10 6 0,000 0,0154404 0,06766778 ! cysteine metabolic process GO:0006534 10 6 0,000 0,0154404 0,06754474 ! regulation of oligodendrocyte differentiation GO:0048713 16 6 0,000 0,0154404 0,06742216 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,0154404 0,06730002 ! glutamate catabolic process GO:0006538 10 6 0,000 0,0154404 0,06717832 ! mitochondrial respiratory chain complex assembly GO:0033108 10 6 0,000 0,0154404 0,06705706 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 10 6 0,000 0,0154404 0,06693623 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! adenohypophysis development GO:0021984 10 6 0,000 0,0154404 0,06681584 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 11 6 0,000 0,0154404 0,06669589 GO:0033135|regulation of peptidyl-serine phosphorylation, ! response to pH GO:0009268 10 6 0,000 0,0154404 0,06657636 ! hyperosmotic response GO:0006972 9 6 0,000 0,0154404 0,06645726 ! chromatin-mediated maintenance of transcription GO:0048096 13 6 0,000 0,0154404 0,06633859 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 9 6 0,000 0,0154404 0,06622034 ! vascular smooth muscle contraction GO:0014829 13 6 0,000 0,0154404 0,06610251 ! urea metabolic process GO:0019627 7 6 0,000 0,0154404 0,0659851 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 7 6 0,000 0,0154404 0,0658681 ! neutrophil activation GO:0042119 8 6 0,000 0,0154404 0,06575152 ! positive regulation of muscle hypertrophy GO:0014742 10 6 0,000 0,0154404 0,06563535 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! regulation of appetite GO:0032098 9 6 0,000 0,0154404 0,06551959 ! cerebral cortex GABAergic interneuron differentiation GO:0021892 11 6 0,000 0,0154404 0,06540424 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,0154404 0,0652893 ! positive regulation of neuroblast proliferation GO:0002052 13 6 0,000 0,0154404 0,06517475 ! neuron apoptosis GO:0051402 9 6 0,000 0,0154404 0,06506061 ! nucleoside salvage GO:0043174 9 6 0,000 0,0154404 0,06494687 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 15 6 0,000 0,0154404 0,06483352 ! positive regulation of nitric-oxide synthase activity GO:0051000 11 6 0,000 0,0154404 0,06472057 ! T cell mediated immunity GO:0002456 16 6 0,000 0,0154404 0,06460802 ! negative regulation of platelet activation GO:0010544 9 6 0,000 0,0154404 0,06449585 GO:0010543|regulation of platelet activation, ! carnitine transport GO:0015879 10 6 0,000 0,0154404 0,06438407 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 14 6 0,000 0,0154404 0,06427268 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,0154404 0,06416167 ! positive regulation of exocytosis GO:0045921 8 6 0,000 0,0154404 0,06405105 ! protein import into mitochondrial inner membrane GO:0045039 8 6 0,000 0,0154404 0,06394081 ! 5S class rRNA transcription GO:0042791 11 6 0,000 0,0154404 0,06383094 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! DNA damage response, signal transduction resulting in transcription GO:0042772 19 6 0,000 0,0154404 0,06372146 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! neuronal ion channel clustering GO:0045161 12 6 0,000 0,0154404 0,06361234 ! regulation of collagen metabolic process GO:0010712 9 6 0,000 0,0154404 0,06350361 ! sodium ion homeostasis GO:0055078 11 6 0,000 0,0154404 0,06339524 ! establishment of spindle localization GO:0051293 12 6 0,000 0,0154404 0,06328724 GO:0051653|spindle localization, ! deoxyribonucleoside metabolic process GO:0009120 8 6 0,000 0,0154404 0,06317961 ! monocyte differentiation GO:0030224 12 6 0,000 0,0154404 0,06307234 ! neural nucleus development GO:0048857 14 6 0,000 0,0154404 0,06296544 ! response to UV-C GO:0010225 11 6 0,000 0,0154404 0,0628589 ! astrocyte development GO:0014002 15 6 0,000 0,0154404 0,06275272 ! protein targeting to lysosome GO:0006622 10 6 0,000 0,0154404 0,0626469 ! purine base biosynthetic process GO:0009113 17 6 0,000 0,0154404 0,06254143 ! interaction with symbiont GO:0051702 13 6 0,000 0,0154404 0,06243632 ! regulation of dendrite development GO:0050773 16 6 0,000 0,0154404 0,06233156 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,0154404 0,06222715 ! positive regulation of cytokine production during immune response GO:0002720 9 6 0,000 0,0154404 0,06212309 ! response to copper ion GO:0046688 10 6 0,000 0,0154404 0,06201938 ! response to exogenous dsRNA GO:0043330 10 6 0,000 0,0154404 0,06191602 ! enucleate erythrocyte differentiation GO:0043353 12 6 0,000 0,0154404 0,06181299 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,0154404 0,06171031 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,0154404 0,06160798 ! negative regulation of protein kinase B signaling cascade GO:0051898 14 6 0,000 0,0154404 0,06150598 ! positive regulation of B cell differentiation GO:0045579 11 6 0,000 0,0154404 0,06140431 ! regulation of dopamine secretion GO:0014059 14 6 0,000 0,0154404 0,06130299 ! nucleoside catabolic process GO:0009164 7 6 0,000 0,0154404 0,06120199 ! hair follicle maturation GO:0048820 7 6 0,000 0,0154404 0,06110133 ! negative regulation of T cell differentiation GO:0045581 14 6 0,000 0,0154404 0,061001 ! Schwann cell development GO:0014044 15 6 0,000 0,0154404 0,060901 ! purine deoxyribonucleotide metabolic process GO:0009151 7 6 0,000 0,0154404 0,06080132 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,0154404 0,06070198 ! regulation of myeloid cell apoptosis GO:0033032 13 6 0,000 0,0154404 0,06060295 ! subpallium development GO:0021544 10 6 0,000 0,0154404 0,06050425 ! negative regulation of multicellular organism growth GO:0040015 8 6 0,000 0,0154404 0,06040587 ! histone ubiquitination GO:0016574 8 6 0,000 0,0154404 0,06030781 ! regulation of myeloid leukocyte mediated immunity GO:0002886 8 6 0,000 0,0154404 0,06021006 ! maintenance of organ identity GO:0048496 9 6 0,000 0,0154404 0,06011264 ! G2 phase GO:0051319 16 6 0,000 0,0154404 0,06001552 GO:0000085|G2 phase of mitotic cell cycle, ! tetracycline transport GO:0015904 8 6 0,000 0,0154404 0,05991872 ! establishment of planar polarity GO:0001736 7 6 0,000 0,0154404 0,05982224 ! regulation of mast cell activation GO:0033003 12 6 0,000 0,0154404 0,05972606 ! membrane to membrane docking GO:0022614 14 6 0,000 0,0154404 0,05963019 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 12 6 0,000 0,0154404 0,05953463 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 8 6 0,000 0,0154404 0,05943937 ! negative regulation of oxidoreductase activity GO:0051354 11 6 0,000 0,0154404 0,05934442 ! receptor internalization GO:0031623 10 6 0,000 0,0154404 0,05924978 ! neutrophil homeostasis GO:0001780 10 6 0,000 0,0154404 0,05915543 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,0154404 0,05906138 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 13 6 0,000 0,0154404 0,05896763 ! protein deubiquitination GO:0016579 14 6 0,000 0,0154404 0,05887418 ! negative regulation of neuroblast proliferation GO:0007406 21 6 0,000 0,0154404 0,05878103 ! protein destabilization GO:0031648 9 6 0,000 0,0154404 0,05868817 ! negative regulation of osteoblast differentiation GO:0045668 17 6 0,000 0,0154404 0,0585956 ! tetrahydrobiopterin biosynthetic process GO:0006729 8 6 0,000 0,0154404 0,05850332 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 0,000 0,0154404 0,05841134 GO:0045625|regulation of T-helper 1 cell differentiation, ! regulation of viral transcription GO:0046782 10 6 0,000 0,0154404 0,05831964 ! regulation of oxygen and reactive oxygen species metabolic process GO:0080010 12 6 0,000 0,0154404 0,05822823 ! nonprotein amino acid metabolic process GO:0019794 12 6 0,000 0,0154404 0,0581371 ! negative regulation of axon extension GO:0030517 21 6 0,000 0,0154404 0,05804626 ! removal of superoxide radicals GO:0019430 11 6 0,000 0,0154404 0,05795571 ! triglyceride catabolic process GO:0019433 10 6 0,000 0,0154404 0,05786544 ! determination of adult lifespan GO:0008340 15 6 0,000 0,0154404 0,05777544 ! ectodermal gut morphogenesis GO:0048567 12 6 0,000 0,0154404 0,05768573 GO:0007439|ectodermal gut development, ! positive regulation of fibrinolysis GO:0051919 8 6 0,000 0,0154404 0,05759629 ! cerebellar cortex formation GO:0021697 8 6 0,000 0,0154404 0,05750714 ! catecholamine transport GO:0051937 9 6 0,000 0,0154404 0,05741825 ! negative regulation of NF-kappaB import into nucleus GO:0042347 14 6 0,000 0,0154404 0,05732964 ! sensory cilium assembly GO:0035058 10 6 0,000 0,0154404 0,05724131 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,0154404 0,05715325 ! cytoplasmic microtubule organization GO:0031122 14 6 0,000 0,0154404 0,05706545 ! maternal placenta development GO:0001893 12 6 0,000 0,0154404 0,05697793 ! regulation of T cell receptor signaling pathway GO:0050856 9 6 0,000 0,0154404 0,05689067 ! negative regulation of smooth muscle contraction GO:0045986 12 6 0,000 0,0154404 0,05680368 ! negative regulation of B cell activation GO:0050869 13 6 0,000 0,0154404 0,05671696 ! protein amino acid prenylation GO:0018346 16 6 0,000 0,0154404 0,0566305 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,0154404 0,05654431 ! positive regulation of microtubule polymerization GO:0031116 13 6 0,000 0,0154404 0,05645837 ! positive regulation of coagulation GO:0050820 12 6 0,000 0,0154404 0,0563727 ! learning or memory GO:0007611 147 73 1,000 0,01545333 0,0563344 ! axon guidance GO:0007411 139 73 1,000 0,01545333 0,05624917 ! regulation of transcription factor activity GO:0051090 126 74 1,000 0,01585622 0,0576285 GO:0090046|regulation of transcription regulator activity, ! meiosis GO:0007126 121 74 1,000 0,01585622 0,05754158 GO:0051327|M phase of meiotic cell cycle, ! regulation of endopeptidase activity GO:0052548 125 74 1,000 0,01585622 0,05745492 ! phosphoinositide-mediated signaling GO:0048015 131 75 1,000 0,0162636 0,05884245 ! meiotic cell cycle GO:0051321 122 75 1,000 0,0162636 0,0587541 ! positive regulation of lymphocyte activation GO:0051251 127 77 1,000 0,01709173 0,06165321 ! activation of protein kinase activity GO:0032147 147 79 1,000 0,01793749 0,06460718 ! regulation of peptidase activity GO:0052547 134 79 1,000 0,01793749 0,06451061 ! positive regulation of phosphorylation GO:0042327 129 79 1,000 0,01793749 0,06441432 ! tRNA transcription GO:0009304 14 7 0,000 0,01799082 0,06450956 ! positive regulation of MHC class II biosynthetic process GO:0045348 11 7 0,000 0,01799082 0,06441357 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 12 7 0,000 0,01799082 0,06431785 ! behavioral response to cocaine GO:0048148 14 7 0,000 0,01799082 0,06422243 ! regulation of helicase activity GO:0051095 15 7 0,000 0,01799082 0,06412728 ! cytokinesis during cell cycle GO:0033205 11 7 0,000 0,01799082 0,06403242 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 12 7 0,000 0,01799082 0,06393784 ! tumor necrosis factor-mediated signaling pathway GO:0033209 10 7 0,000 0,01799082 0,06384353 ! chaperone mediated protein folding requiring cofactor GO:0051085 11 7 0,000 0,01799082 0,06374951 ! negative regulation of cellular catabolic process GO:0031330 12 7 0,000 0,01799082 0,06365576 ! prostate gland development GO:0030850 13 7 0,000 0,01799082 0,06356228 ! nucleotide-sugar transport GO:0015780 12 7 0,000 0,01799082 0,06346909 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,01799082 0,06337616 GO:0070193|synaptonemal complex organization, ! forebrain neuron differentiation GO:0021879 16 7 0,000 0,01799082 0,0632835 ! regulation of lipid catabolic process GO:0050994 15 7 0,000 0,01799082 0,06319112 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,01799082 0,063099 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid biosynthetic process GO:0046460 11 7 0,000 0,01799082 0,06300716 GO:0046463|acylglycerol biosynthetic process, ! platelet activating factor metabolic process GO:0046469 11 7 0,000 0,01799082 0,06291558 ! N-acetylglucosamine catabolic process GO:0006046 9 7 0,000 0,01799082 0,06282426 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! Golgi to plasma membrane transport GO:0006893 14 7 0,000 0,01799082 0,06273321 ! SMAD protein complex assembly GO:0007183 12 7 0,000 0,01799082 0,06264243 ! glycolipid transport GO:0046836 10 7 0,000 0,01799082 0,0625519 ! protein amino acid sulfation GO:0006477 10 7 0,000 0,01799082 0,06246164 GO:0051923|sulfation, ! neuron adhesion GO:0007158 12 7 0,000 0,01799082 0,06237164 ! negative regulation of JAK-STAT cascade GO:0046426 17 7 0,000 0,01799082 0,06228189 ! actin-myosin filament sliding GO:0033275 11 7 0,000 0,01799082 0,06219241 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! establishment of tissue polarity GO:0007164 8 7 0,000 0,01799082 0,06210318 ! protein thiol-disulfide exchange GO:0006467 9 7 0,000 0,01799082 0,06201421 ! receptor guanylyl cyclase signaling pathway GO:0007168 8 7 0,000 0,01799082 0,06192549 ! nucleotide-excision repair, DNA incision GO:0033683 10 7 0,000 0,01799082 0,06183702 ! mRNA stabilization GO:0048255 18 7 0,000 0,01799082 0,06174881 GO:0043489|RNA stabilization, ! pericardium development GO:0060039 14 7 0,000 0,01799082 0,06166085 ! glucocorticoid receptor signaling pathway GO:0042921 13 7 0,000 0,01799082 0,06157314 GO:0031958|corticosteroid receptor signaling pathway, ! fibril organization GO:0043206 16 7 0,000 0,01799082 0,06148568 ! oxaloacetate metabolic process GO:0006107 10 7 0,000 0,01799082 0,06139846 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,01799082 0,0613115 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 15 7 0,000 0,01799082 0,06122478 ! positive regulation of neurotransmitter transport GO:0051590 16 7 0,000 0,01799082 0,0611383 ! lipoprotein transport GO:0042953 14 7 0,000 0,01799082 0,06105207 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,01799082 0,06096608 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,01799082 0,06088033 ! rhythmic behavior GO:0007622 15 7 0,000 0,01799082 0,06079483 ! regulation of dopamine metabolic process GO:0042053 11 7 0,000 0,01799082 0,06070956 GO:0042069|regulation of catecholamine metabolic process, ! estrogen metabolic process GO:0008210 17 7 0,000 0,01799082 0,06062453 ! sensory perception of temperature stimulus GO:0050951 11 7 0,000 0,01799082 0,06053974 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 14 7 0,000 0,01799082 0,06045519 ! regulation of odontogenesis GO:0042481 13 7 0,000 0,01799082 0,06037087 ! synaptic transmission, dopaminergic GO:0001963 12 7 0,000 0,01799082 0,06028679 ! amyloid precursor protein catabolic process GO:0042987 11 7 0,000 0,01799082 0,06020294 ! mechanosensory behavior GO:0007638 14 7 0,000 0,01799082 0,06011933 ! DNA ligation during DNA repair GO:0051103 13 7 0,000 0,01799082 0,06003594 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,01799082 0,05995279 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 10 7 0,000 0,01799082 0,05986987 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,01799082 0,05978718 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,01799082 0,05970471 ! spinal cord patterning GO:0021511 13 7 0,000 0,01799082 0,05962247 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 20 7 0,000 0,01799082 0,05954046 ! regulation of transcriptional preinitiation complex assembly GO:0045898 12 7 0,000 0,01799082 0,05945868 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 12 7 0,000 0,01799082 0,05937711 ! adrenal gland development GO:0030325 17 7 0,000 0,01799082 0,05929578 ! induction of apoptosis by oxidative stress GO:0008631 8 7 0,000 0,01799082 0,05921466 ! regulation of defense response to virus by host GO:0050691 7 7 0,000 0,01799082 0,05913377 ! ovulation GO:0030728 9 7 0,000 0,01799082 0,05905309 ! deoxyribonucleotide biosynthetic process GO:0009263 10 7 0,000 0,01799082 0,05897264 ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 9 7 0,000 0,01799082 0,0588924 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 19 7 0,000 0,01799082 0,05881239 ! microtubule nucleation GO:0007020 20 7 0,000 0,01799082 0,05873259 ! proline biosynthetic process GO:0006561 10 7 0,000 0,01799082 0,058653 ! thyroid hormone generation GO:0006590 13 7 0,000 0,01799082 0,05857363 ! regulation of granule cell precursor proliferation GO:0021936 13 7 0,000 0,01799082 0,05849448 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 11 7 0,000 0,01799082 0,05841554 ! tetrahydrobiopterin metabolic process GO:0046146 10 7 0,000 0,01799082 0,05833681 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,01799082 0,0582583 ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,01799082 0,05817999 ! galactose metabolic process GO:0006012 13 7 0,000 0,01799082 0,0581019 ! vesicle fusion GO:0006906 17 7 0,000 0,01799082 0,05802402 ! response to dietary excess GO:0002021 8 7 0,000 0,01799082 0,05794634 ! maintenance of protein location in nucleus GO:0051457 19 7 0,000 0,01799082 0,05786887 ! intracellular pH reduction GO:0051452 11 7 0,000 0,01799082 0,05779161 GO:0045851|pH reduction, ! glycerol ether catabolic process GO:0044269 12 7 0,000 0,01799082 0,05771455 GO:0046464|acylglycerol catabolic process, ! melanosome organization GO:0032438 9 7 0,000 0,01799082 0,0576377 ! organ growth GO:0035265 15 7 0,000 0,01799082 0,05756106 ! purine salvage GO:0043101 10 7 0,000 0,01799082 0,05748462 ! nucleoside transport GO:0015858 8 7 0,000 0,01799082 0,05740838 ! negative regulation of DNA recombination GO:0045910 15 7 0,000 0,01799082 0,05733234 ! parturition GO:0007567 14 7 0,000 0,01799082 0,0572565 ! positive regulation of mitotic cell cycle GO:0045931 12 7 0,000 0,01799082 0,05718087 ! rRNA modification GO:0000154 14 7 0,000 0,01799082 0,05710543 ! regulation of chromatin assembly or disassembly GO:0001672 13 7 0,000 0,01799082 0,05703019 ! spindle checkpoint GO:0031577 15 7 0,000 0,01799082 0,05695515 ! wound healing, spreading of epidermal cells GO:0035313 14 7 0,000 0,01799082 0,05688031 ! regulation of cholesterol biosynthetic process GO:0045540 12 7 0,000 0,01799082 0,05680566 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,01799082 0,05673121 ! negative regulation of peptide secretion GO:0002792 10 7 0,000 0,01799082 0,05665696 GO:0046676|negative regulation of insulin secretion, ! centrosome duplication GO:0051298 13 7 0,000 0,01799082 0,0565829 ! hyaluronan metabolic process GO:0030212 8 7 0,000 0,01799082 0,05650903 ! G1 DNA damage checkpoint GO:0031571 21 7 0,000 0,01799082 0,05643535 ! anterograde axon cargo transport GO:0008089 18 7 0,000 0,01799082 0,05636187 ! fibrinolysis GO:0042730 10 7 0,000 0,01799082 0,05628858 ! negative regulation of insulin receptor signaling pathway GO:0046627 15 7 0,000 0,01799082 0,05621548 ! eating behavior GO:0042755 7 7 0,000 0,01799082 0,05614256 ! B cell lineage commitment GO:0002326 21 7 0,000 0,01799082 0,05606984 ! antigen processing and presentation of exogenous antigen GO:0019884 10 7 0,000 0,01799082 0,0559973 ! positive regulation of systemic arterial blood pressure GO:0003084 10 7 0,000 0,01799082 0,05592496 ! negative regulation of interferon-gamma production GO:0032689 12 7 0,000 0,01799082 0,05585279 ! negative regulation of systemic arterial blood pressure GO:0003085 19 7 0,000 0,01799082 0,05578082 ! negative regulation of focal adhesion formation GO:0051895 20 7 0,000 0,01799082 0,05570903 ! respiratory chain complex IV assembly GO:0008535 14 7 0,000 0,01799082 0,05563742 ! cranial nerve morphogenesis GO:0021602 11 7 0,000 0,01799082 0,055566 ! phosphatidylinositol biosynthetic process GO:0006661 14 7 0,000 0,01799082 0,05549476 ! regulation of interleukin-1 beta production GO:0032651 10 7 0,000 0,01799082 0,05542371 ! phosphatidylserine metabolic process GO:0006658 8 7 0,000 0,01799082 0,05535283 ! regulation of interleukin-10 production GO:0032653 13 7 0,000 0,01799082 0,05528214 ! positive regulation of tumor necrosis factor production GO:0032760 9 7 0,000 0,01799082 0,05521163 ! positive regulation of monooxygenase activity GO:0032770 12 7 0,000 0,01799082 0,05514129 ! cell differentiation in hindbrain GO:0021533 10 7 0,000 0,01799082 0,05507114 ! regulation of meiosis GO:0040020 12 7 0,000 0,01799082 0,05500116 GO:0051445|regulation of meiotic cell cycle, ! transcription from RNA polymerase I promoter GO:0006360 13 7 0,000 0,01799082 0,05493137 ! T cell lineage commitment GO:0002360 16 7 0,000 0,01799082 0,05486174 ! positive regulation of immunoglobulin mediated immune response GO:0002891 13 7 0,000 0,01799082 0,0547923 GO:0002714|positive regulation of B cell mediated immunity, ! regulation of lipid transport GO:0032368 14 7 0,000 0,01799082 0,05472303 ! oxygen homeostasis GO:0032364 12 7 0,000 0,01799082 0,05465393 ! transcription termination GO:0006353 13 7 0,000 0,01799082 0,05458501 ! response to tumor cell GO:0002347 13 7 0,000 0,01799082 0,05451627 ! coenzyme A metabolic process GO:0015936 12 7 0,000 0,01799082 0,05444769 ! anaphase GO:0051322 17 7 0,000 0,01799082 0,05437929 GO:0000090|mitotic anaphase, ! peptidyl-histidine modification GO:0018202 16 7 0,000 0,01799082 0,05431106 ! axonal fasciculation GO:0007413 18 7 0,000 0,01799082 0,054243 ! negative regulation of nuclear division GO:0051784 14 7 0,000 0,01799082 0,05417511 GO:0045839|negative regulation of mitosis, ! lipopolysaccharide-mediated signaling pathway GO:0031663 12 7 0,000 0,01799082 0,0541074 ! peptidyl-threonine modification GO:0018210 25 7 0,000 0,01799082 0,05403985 ! diuresis GO:0030146 12 7 0,000 0,01799082 0,05397246 GO:0030147|natriuresis, ! regulation of myoblast differentiation GO:0045661 16 7 0,000 0,01799082 0,05390525 ! thiamin metabolic process GO:0006772 7 7 0,000 0,01799082 0,0538382 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,01799082 0,05377132 ! positive regulation of leukocyte chemotaxis GO:0002690 16 7 0,000 0,01799082 0,05370461 GO:0002688|regulation of leukocyte chemotaxis, ! antibiotic transport GO:0042891 9 7 0,000 0,01799082 0,05363806 ! regulation of epidermal cell differentiation GO:0045604 8 7 0,000 0,01799082 0,05357168 ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,01799082 0,05350546 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,01799082 0,0534394 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,01799082 0,05337351 ! aspartate family amino acid catabolic process GO:0009068 9 7 0,000 0,01799082 0,05330778 ! dopamine biosynthetic process GO:0042416 18 7 0,000 0,01799082 0,05324221 ! glycolipid catabolic process GO:0019377 15 7 0,000 0,01799082 0,0531768 GO:0046479|glycosphingolipid catabolic process, ! regulation of protein homodimerization activity GO:0043496 18 7 0,000 0,01799082 0,05311155 ! lymph node development GO:0048535 10 7 0,000 0,01799082 0,05304647 ! positive regulation of ATPase activity GO:0032781 11 7 0,000 0,01799082 0,05298154 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,01799082 0,05291677 ! regulation of T cell mediated cytotoxicity GO:0001914 17 7 0,000 0,01799082 0,05285216 ! endosome to lysosome transport GO:0008333 11 7 0,000 0,01799082 0,0527877 ! protein modification by small protein removal GO:0070646 16 7 0,000 0,01799082 0,05272341 ! adult feeding behavior GO:0008343 9 7 0,000 0,01799082 0,05265927 ! negative regulation of telomere maintenance GO:0032205 11 7 0,000 0,01799082 0,05259528 ! toll-like receptor signaling pathway GO:0002224 8 7 0,000 0,01799082 0,05253145 ! regulation of synaptic transmission, dopaminergic GO:0032225 11 7 0,000 0,01799082 0,05246778 ! muscle adaptation GO:0043500 14 7 0,000 0,01799082 0,05240426 ! embryonic heart tube development GO:0035050 10 7 0,000 0,01799082 0,05234089 ! retina homeostasis GO:0001895 12 7 0,000 0,01799082 0,05227768 ! negative regulation of nucleotide metabolic process GO:0045980 11 7 0,000 0,01799082 0,05221462 ! positive regulation of smooth muscle contraction GO:0045987 10 7 0,000 0,01799082 0,05215171 ! fusion of sperm to egg plasma membrane GO:0007342 10 7 0,000 0,01799082 0,05208895 ! protein prenylation GO:0018342 18 7 0,000 0,01799082 0,05202634 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 15 7 0,000 0,01799082 0,05196388 ! regulation of microtubule polymerization GO:0031113 15 7 0,000 0,01799082 0,05190158 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,01799082 0,05183942 ! muscle cell differentiation GO:0042692 159 80 1,000 0,01836692 0,05285983 ! positive regulation of phosphorus metabolic process GO:0010562 136 81 1,000 0,01880069 0,05404357 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 171 81 1,000 0,01880069 0,05397907 ! intracellular protein transmembrane transport GO:0065002 153 81 1,000 0,01880069 0,05391474 ! regulation of neuron differentiation GO:0045664 167 81 1,000 0,01880069 0,05385055 ! response to nutrient GO:0007584 125 82 1,000 0,01923877 0,05503982 ! response to oxygen levels GO:0070482 176 83 1,000 0,01968114 0,05623851 ! negative regulation of transport GO:0051051 153 84 1,000 0,02012777 0,05744651 ! negative regulation of growth GO:0045926 155 84 1,000 0,02012777 0,05737845 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 15 8 0,000 0,02053472 0,05846927 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 16 8 0,000 0,02053472 0,05840015 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of smooth muscle cell proliferation GO:0048662 16 8 0,000 0,02053472 0,0583312 ! somatic diversification of immune receptors via somatic mutation GO:0002566 11 8 0,000 0,02053472 0,05826242 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 14 8 0,000 0,02053472 0,05819379 ! regulation of interferon-alpha production GO:0032647 11 8 0,000 0,02053472 0,05812533 ! generation of neurons in the forebrain GO:0021872 18 8 0,000 0,02053472 0,05805703 ! glycerol-3-phosphate metabolic process GO:0006072 13 8 0,000 0,02053472 0,05798889 ! neutral lipid catabolic process GO:0046461 13 8 0,000 0,02053472 0,0579209 ! regulation of cellular amine metabolic process GO:0033238 12 8 0,000 0,02053472 0,05785308 ! meiotic prophase I GO:0007128 13 8 0,000 0,02053472 0,05778542 ! carbohydrate phosphorylation GO:0046835 11 8 0,000 0,02053472 0,05771791 ! oligopeptide transport GO:0006857 15 8 0,000 0,02053472 0,05765056 ! UTP metabolic process GO:0046051 8 8 0,000 0,02053472 0,05758337 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! signal peptide processing GO:0006465 12 8 0,000 0,02053472 0,05751633 ! prostaglandin biosynthetic process GO:0001516 14 8 0,000 0,02053472 0,05744945 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 14 8 0,000 0,02053472 0,05738273 ! macrophage chemotaxis GO:0048246 12 8 0,000 0,02053472 0,05731616 ! succinate metabolic process GO:0006105 14 8 0,000 0,02053472 0,05724975 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,02053472 0,05718348 ! detection of mechanical stimulus involved in sensory perception GO:0050974 18 8 0,000 0,02053472 0,05711738 ! negative regulation of muscle cell differentiation GO:0051148 15 8 0,000 0,02053472 0,05705142 ! T-helper 1 type immune response GO:0042088 12 8 0,000 0,02053472 0,05698562 ! regulation of response to extracellular stimulus GO:0032104 13 8 0,000 0,02053472 0,05691997 GO:0032107|regulation of response to nutrient levels, ! chaperone-mediated protein complex assembly GO:0051131 13 8 0,000 0,02053472 0,05685447 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,02053472 0,05678912 ! ganglioside metabolic process GO:0001573 19 8 0,000 0,02053472 0,05672392 ! reflex GO:0060004 16 8 0,000 0,02053472 0,05665887 ! negative regulation of endocytosis GO:0045806 11 8 0,000 0,02053472 0,05659396 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 14 8 0,000 0,02053472 0,05652921 ! endothelial cell differentiation GO:0045446 17 8 0,000 0,02053472 0,05646461 ! glycerol ether biosynthetic process GO:0046504 13 8 0,000 0,02053472 0,05640015 ! glycerolipid catabolic process GO:0046503 13 8 0,000 0,02053472 0,05633584 ! hemoglobin metabolic process GO:0020027 13 8 0,000 0,02053472 0,05627167 ! inositol phosphate-mediated signaling GO:0048016 11 8 0,000 0,02053472 0,05620766 ! pigment granule organization GO:0048753 16 8 0,000 0,02053472 0,05614378 ! activation of caspase activity by cytochrome c GO:0008635 14 8 0,000 0,02053472 0,05608006 ! regulation of defense response to virus by virus GO:0050690 18 8 0,000 0,02053472 0,05601647 ! astrocyte differentiation GO:0048708 18 8 0,000 0,02053472 0,05595304 ! histidine metabolic process GO:0006547 16 8 0,000 0,02053472 0,05588974 GO:0009075|histidine family amino acid metabolic process, ! outer mitochondrial membrane organization GO:0007008 16 8 0,000 0,02053472 0,05582659 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! inner mitochondrial membrane organization GO:0007007 14 8 0,000 0,02053472 0,05576358 ! glycine catabolic process GO:0006546 13 8 0,000 0,02053472 0,05570071 ! cytoskeletal anchoring at plasma membrane GO:0007016 29 8 0,000 0,02053472 0,05563798 ! L-phenylalanine metabolic process GO:0006558 11 8 0,000 0,02053472 0,0555754 GO:0006559|L-phenylalanine catabolic process, ! ER overload response GO:0006983 12 8 0,000 0,02053472 0,05551296 ! regulation of interleukin-6 biosynthetic process GO:0045408 11 8 0,000 0,02053472 0,05545065 ! regulation of pigmentation during development GO:0048070 24 8 0,000 0,02053472 0,05538849 ! melanin metabolic process GO:0006582 15 8 0,000 0,02053472 0,05532646 ! embryonic eye morphogenesis GO:0048048 14 8 0,000 0,02053472 0,05526458 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,02053472 0,05520283 ! positive regulation of endothelial cell migration GO:0010595 19 8 0,000 0,02053472 0,05514122 ! macrophage activation GO:0042116 12 8 0,000 0,02053472 0,05507974 ! regulation of muscle hypertrophy GO:0014743 12 8 0,000 0,02053472 0,05501841 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 17 8 0,000 0,02053472 0,05495721 ! positive regulation of insulin secretion GO:0032024 15 8 0,000 0,02053472 0,05489614 ! synaptic transmission, glutamatergic GO:0035249 17 8 0,000 0,02053472 0,05483522 ! positive regulation of mesenchymal cell proliferation GO:0002053 27 8 0,000 0,02053472 0,05477442 ! regulation of vascular permeability GO:0043114 12 8 0,000 0,02053472 0,05471377 ! regulation of multicellular organismal metabolic process GO:0044246 11 8 0,000 0,02053472 0,05465324 ! osteoblast development GO:0002076 16 8 0,000 0,02053472 0,05459285 ! positive regulation of vasodilation GO:0045909 13 8 0,000 0,02053472 0,05453259 ! negative regulation of muscle contraction GO:0045932 15 8 0,000 0,02053472 0,05447247 ! negative regulation of translational initiation GO:0045947 10 8 0,000 0,02053472 0,05441248 ! Schwann cell differentiation GO:0014037 19 8 0,000 0,02053472 0,05435262 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 19 8 0,000 0,02053472 0,05429289 ! lipopolysaccharide biosynthetic process GO:0009103 9 8 0,000 0,02053472 0,05423329 ! response to UV-B GO:0010224 16 8 0,000 0,02053472 0,05417383 ! protein targeting to vacuole GO:0006623 12 8 0,000 0,02053472 0,05411449 ! protein retention in ER lumen GO:0006621 14 8 0,000 0,02053472 0,05405528 ! intermediate filament organization GO:0045109 12 8 0,000 0,02053472 0,05399621 ! positive regulation of myeloid leukocyte differentiation GO:0002763 24 8 0,000 0,02053472 0,05393726 ! cellular extravasation GO:0045123 12 8 0,000 0,02053472 0,05387844 ! cardiac muscle cell development GO:0055013 13 8 0,000 0,02053472 0,05381975 ! regulation of circadian rhythm GO:0042752 16 8 0,000 0,02053472 0,05376119 ! response to antibiotic GO:0046677 11 8 0,000 0,02053472 0,05370275 ! transcription-coupled nucleotide-excision repair GO:0006283 11 8 0,000 0,02053472 0,05364444 ! positive regulation of production of molecular mediator of immune response GO:0002702 25 8 0,000 0,02053472 0,05358626 ! DNA topological change GO:0006265 12 8 0,000 0,02053472 0,0535282 ! response to tropane GO:0014073 15 8 0,000 0,02053472 0,05347027 GO:0042220|response to cocaine, ! regulation of fat cell differentiation GO:0045598 15 8 0,000 0,02053472 0,05341247 ! melanosome transport GO:0032402 13 8 0,000 0,02053472 0,05335478 ! regulation of interleukin-4 production GO:0032673 17 8 0,000 0,02053472 0,05329723 ! glycosylceramide metabolic process GO:0006677 10 8 0,000 0,02053472 0,0532398 ! mast cell activation GO:0045576 14 8 0,000 0,02053472 0,05318249 ! multicellular organismal aging GO:0010259 18 8 0,000 0,02053472 0,0531253 ! regulation of focal adhesion formation GO:0051893 22 8 0,000 0,02053472 0,05306824 ! dendrite morphogenesis GO:0048813 13 8 0,000 0,02053472 0,0530113 ! regulation of interleukin-1 production GO:0032652 13 8 0,000 0,02053472 0,05295448 ! nucleosome disassembly GO:0006337 14 8 0,000 0,02053472 0,05289778 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 11 8 0,000 0,02053472 0,05284121 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,02053472 0,05278475 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 12 8 0,000 0,02053472 0,05272842 ! establishment of chromosome localization GO:0051303 12 8 0,000 0,02053472 0,05267221 GO:0050000|chromosome localization, ! mitochondrion morphogenesis GO:0070584 14 8 0,000 0,02053472 0,05261611 ! intracellular lipid transport GO:0032365 13 8 0,000 0,02053472 0,05256014 ! regulation of immune response to tumor cell GO:0002837 15 8 0,000 0,02053472 0,05250428 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of T-helper 1 type immune response GO:0002825 9 8 0,000 0,02053472 0,05244855 ! regulation of macrophage activation GO:0043030 15 8 0,000 0,02053472 0,05239293 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 15 8 0,000 0,02053472 0,05233743 ! positive regulation of epidermis development GO:0045684 13 8 0,000 0,02053472 0,05228204 ! neuromuscular process controlling posture GO:0050884 14 8 0,000 0,02053472 0,05222678 ! regulation of synaptic transmission, glutamatergic GO:0051966 17 8 0,000 0,02053472 0,05217163 ! hormone catabolic process GO:0042447 17 8 0,000 0,02053472 0,05211659 ! positive regulation of glucose import GO:0046326 8 8 0,000 0,02053472 0,05206168 GO:0010828|positive regulation of glucose transport, ! myeloid cell homeostasis GO:0002262 13 8 0,000 0,02053472 0,05200687 ! regulation of Rac protein signal transduction GO:0035020 11 8 0,000 0,02053472 0,05195219 ! ATP catabolic process GO:0006200 11 8 0,000 0,02053472 0,05189762 ! blastocyst growth GO:0001832 19 8 0,000 0,02053472 0,05184316 ! trophectodermal cell differentiation GO:0001829 13 8 0,000 0,02053472 0,05178882 ! negative regulation of organic acid transport GO:0032891 13 8 0,000 0,02053472 0,05173459 ! pattern recognition receptor signaling pathway GO:0002221 10 8 0,000 0,02053472 0,05168047 ! negative regulation of calcium ion transport GO:0051926 13 8 0,000 0,02053472 0,05162647 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,02053472 0,05157258 ! regulation of synaptic transmission, GABAergic GO:0032228 14 8 0,000 0,02053472 0,0515188 ! negative regulation of blood vessel endothelial cell migration GO:0043537 21 8 0,000 0,02053472 0,05146514 ! positive regulation of NF-kappaB import into nucleus GO:0042346 13 8 0,000 0,02053472 0,05141158 ! pyrimidine nucleotide catabolic process GO:0006244 14 8 0,000 0,02053472 0,05135814 ! amino sugar catabolic process GO:0046348 10 8 0,000 0,02053472 0,05130481 GO:0006043|glucosamine catabolic process, ! B cell receptor signaling pathway GO:0050853 16 8 0,000 0,02053472 0,05125159 ! regulation of growth hormone secretion GO:0060123 16 8 0,000 0,02053472 0,05119848 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 14 8 0,000 0,02053472 0,05114548 ! behavioral response to nicotine GO:0035095 12 8 0,000 0,02053472 0,05109259 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,02053472 0,0510398 GO:0000076|DNA replication checkpoint, ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 18 8 0,000 0,02053472 0,05098713 ! NAD biosynthetic process GO:0009435 13 8 0,000 0,02053472 0,05093457 ! response to unfolded protein GO:0006986 131 85 1,000 0,02057863 0,05099093 ! nucleosome assembly GO:0006334 122 85 1,000 0,02057863 0,05093847 ! one-carbon metabolic process GO:0006730 154 85 1,000 0,02057863 0,05088612 ! positive regulation of cell activation GO:0050867 145 85 1,000 0,02057863 0,05083387 GO:0002696|positive regulation of leukocyte activation, ! chromatin assembly GO:0031497 124 86 1,000 0,02103371 0,05190473 ! regulation of DNA binding GO:0051101 155 88 1,000 0,02195641 0,05412615 ! gland development GO:0048732 206 88 1,000 0,02195641 0,05407075 ! regulation of cell adhesion GO:0030155 212 89 1,000 0,02242398 0,05516575 ! protein-DNA complex assembly GO:0065004 130 90 1,000 0,02289567 0,05626863 ! axon extension GO:0048675 15 9 0,000 0,02307211 0,05664438 ! autophagic vacuole formation GO:0000045 15 9 0,000 0,02307211 0,05658664 ! 'de novo' posttranslational protein folding GO:0051084 14 9 0,000 0,02307211 0,05652901 ! regulation of epithelial cell differentiation GO:0030856 14 9 0,000 0,02307211 0,05647151 ! pentose-phosphate shunt GO:0006098 16 9 0,000 0,02307211 0,05641412 GO:0006740|NADPH regeneration, ! associative learning GO:0008306 20 9 0,000 0,02307211 0,05635684 ! DNA synthesis during DNA repair GO:0000731 14 9 0,000 0,02307211 0,05629969 ! cell proliferation in forebrain GO:0021846 15 9 0,000 0,02307211 0,05624265 ! phosphate transport GO:0006817 19 9 0,000 0,02307211 0,05618572 ! reproductive behavior GO:0019098 19 9 0,000 0,02307211 0,05612891 ! cellular copper ion homeostasis GO:0006878 12 9 0,000 0,02307211 0,05607221 ! regulation of epidermal growth factor receptor activity GO:0007176 16 9 0,000 0,02307211 0,05601563 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,02307211 0,05595917 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! Golgi to endosome transport GO:0006895 23 9 0,000 0,02307211 0,05590281 ! GTP metabolic process GO:0046039 9 9 0,000 0,02307211 0,05584657 ! RNA methylation GO:0001510 15 9 0,000 0,02307211 0,05579044 ! elastic fiber assembly GO:0048251 15 9 0,000 0,02307211 0,05573443 ! induction of positive chemotaxis GO:0050930 15 9 0,000 0,02307211 0,05567853 ! regulation of activated T cell proliferation GO:0046006 16 9 0,000 0,02307211 0,05562274 ! artery development GO:0060840 24 9 0,000 0,02307211 0,05556706 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 12 9 0,000 0,02307211 0,05551149 ! cerebral cortex cell migration GO:0021795 15 9 0,000 0,02307211 0,05545604 ! keratinocyte proliferation GO:0043616 14 9 0,000 0,02307211 0,05540069 ! cytoplasmic sequestering of transcription factor GO:0042994 14 9 0,000 0,02307211 0,05534546 ! chemosensory behavior GO:0007635 20 9 0,000 0,02307211 0,05529033 ! microtubule bundle formation GO:0001578 21 9 0,000 0,02307211 0,05523532 ! middle ear morphogenesis GO:0042474 14 9 0,000 0,02307211 0,05518041 ! amyloid precursor protein metabolic process GO:0042982 14 9 0,000 0,02307211 0,05512561 ! leukocyte degranulation GO:0043299 16 9 0,000 0,02307211 0,05507092 ! bile acid and bile salt transport GO:0015721 13 9 0,000 0,02307211 0,05501634 ! regulation of mesenchymal cell proliferation GO:0010464 28 9 0,000 0,02307211 0,05496187 ! positive regulation of gene expression, epigenetic GO:0045815 18 9 0,000 0,02307211 0,05490751 ! ribonucleoside triphosphate catabolic process GO:0009203 12 9 0,000 0,02307211 0,05485325 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! lipopolysaccharide metabolic process GO:0008653 10 9 0,000 0,02307211 0,0547991 ! protein targeting to ER GO:0045047 22 9 0,000 0,02307211 0,05474506 ! ceramide biosynthetic process GO:0046513 19 9 0,000 0,02307211 0,05469113 ! nerve growth factor receptor signaling pathway GO:0048011 19 9 0,000 0,02307211 0,0546373 ! T cell selection GO:0045058 23 9 0,000 0,02307211 0,05458357 ! embryonic cranial skeleton morphogenesis GO:0048701 17 9 0,000 0,02307211 0,05452995 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,02307211 0,05447644 GO:0006600|creatine metabolic process, ! endosome organization GO:0007032 17 9 0,000 0,02307211 0,05442303 ! regulation of phosphoprotein phosphatase activity GO:0043666 24 9 0,000 0,02307211 0,05436973 ! regulation of type I interferon production GO:0032479 12 9 0,000 0,02307211 0,05431653 ! mannose metabolic process GO:0006013 13 9 0,000 0,02307211 0,05426343 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 21 9 0,000 0,02307211 0,05421044 ! retrograde transport, endosome to Golgi GO:0042147 24 9 0,000 0,02307211 0,05415755 ! Rac protein signal transduction GO:0016601 17 9 0,000 0,02307211 0,05410477 ! receptor clustering GO:0043113 18 9 0,000 0,02307211 0,05405209 ! neurotransmitter catabolic process GO:0042135 15 9 0,000 0,02307211 0,05399951 ! positive regulation of calcium ion transport into cytosol GO:0010524 12 9 0,000 0,02307211 0,05394703 ! ruffle organization GO:0031529 15 9 0,000 0,02307211 0,05389465 ! retinol metabolic process GO:0042572 18 9 0,000 0,02307211 0,05384238 ! intestinal cholesterol absorption GO:0030299 16 9 0,000 0,02307211 0,05379021 ! behavioral fear response GO:0001662 22 9 0,000 0,02307211 0,05373813 GO:0002209|behavioral defense response, ! determination of anterior/posterior axis, embryo GO:0008595 16 9 0,000 0,02307211 0,05368616 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 22 9 0,000 0,02307211 0,05363429 ! chondroitin sulfate biosynthetic process GO:0030206 17 9 0,000 0,02307211 0,05358252 GO:0030204|chondroitin sulfate metabolic process, ! oligodendrocyte development GO:0014003 10 9 0,000 0,02307211 0,05353085 ! alpha-beta T cell differentiation GO:0046632 21 9 0,000 0,02307211 0,05347928 ! segment specification GO:0007379 13 9 0,000 0,02307211 0,05342781 ! peptidyl-asparagine modification GO:0018196 15 9 0,000 0,02307211 0,05337643 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! base-excision repair, AP site formation GO:0006285 14 9 0,000 0,02307211 0,05332516 ! thiamin and derivative metabolic process GO:0042723 10 9 0,000 0,02307211 0,05327398 ! response to amine stimulus GO:0014075 13 9 0,000 0,02307211 0,05322291 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! establishment of melanosome localization GO:0032401 14 9 0,000 0,02307211 0,05317193 ! nucleoside diphosphate metabolic process GO:0009132 13 9 0,000 0,02307211 0,05312105 ! erythrocyte development GO:0048821 15 9 0,000 0,02307211 0,05307026 ! gas homeostasis GO:0033483 16 9 0,000 0,02307211 0,05301957 ! nucleoside bisphosphate metabolic process GO:0033865 18 9 0,000 0,02307211 0,05296898 ! regulation of mitochondrial membrane potential GO:0051881 17 9 0,000 0,02307211 0,05291849 ! renal water homeostasis GO:0003091 14 9 0,000 0,02307211 0,05286809 ! postreplication repair GO:0006301 22 9 0,000 0,02307211 0,05281779 ! protein import into peroxisome matrix GO:0016558 16 9 0,000 0,02307211 0,05276758 ! spinal cord motor neuron differentiation GO:0021522 15 9 0,000 0,02307211 0,05271747 ! icosanoid secretion GO:0032309 15 9 0,000 0,02307211 0,05266745 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 14 9 0,000 0,02307211 0,05261753 ! cerebellum morphogenesis GO:0021587 14 9 0,000 0,02307211 0,0525677 GO:0021696|cerebellar cortex morphogenesis, ! synaptic vesicle endocytosis GO:0048488 20 9 0,000 0,02307211 0,05251797 ! regulation of cell division GO:0051302 15 9 0,000 0,02307211 0,05246833 ! retinal ganglion cell axon guidance GO:0031290 13 9 0,000 0,02307211 0,05241878 ! morphogenesis of a polarized epithelium GO:0001738 11 9 0,000 0,02307211 0,05236933 ! regulation of transcription from RNA polymerase III promoter GO:0006359 13 9 0,000 0,02307211 0,05231997 ! sterol catabolic process GO:0016127 11 9 0,000 0,02307211 0,05227071 GO:0006707|cholesterol catabolic process, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 15 9 0,000 0,02307211 0,05222154 ! negative regulation of cytokine secretion GO:0050710 14 9 0,000 0,02307211 0,05217245 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 20 9 0,000 0,02307211 0,05212347 GO:0002820|negative regulation of adaptive immune response, ! S phase GO:0051320 9 9 0,000 0,02307211 0,05207457 GO:0000084|S phase of mitotic cell cycle, ! positive regulation of erythrocyte differentiation GO:0045648 29 9 0,000 0,02307211 0,05202577 ! regulation of macrophage differentiation GO:0045649 15 9 0,000 0,02307211 0,05197705 ! musculoskeletal movement GO:0050881 14 9 0,000 0,02307211 0,05192843 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 19 9 0,000 0,02307211 0,0518799 ! branched chain family amino acid catabolic process GO:0009083 17 9 0,000 0,02307211 0,05183146 ! regulation of synaptogenesis GO:0051963 15 9 0,000 0,02307211 0,05178311 ! purine base metabolic process GO:0006144 21 9 0,000 0,02307211 0,05173485 ! serine family amino acid catabolic process GO:0009071 16 9 0,000 0,02307211 0,05168668 ! pigment granule transport GO:0051904 17 9 0,000 0,02307211 0,0516386 ! regulation of fibrinolysis GO:0051917 16 9 0,000 0,02307211 0,05159061 ! regulation of telomere maintenance GO:0032204 14 9 0,000 0,02307211 0,0515427 ! pyrimidine base metabolic process GO:0006206 17 9 0,000 0,02307211 0,05149489 ! regulation of muscle adaptation GO:0043502 14 9 0,000 0,02307211 0,05144717 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,02307211 0,05139953 ! mitochondrion localization GO:0051646 15 9 0,000 0,02307211 0,05135198 ! response to protein stimulus GO:0051789 149 91 1,000 0,02337145 0,05197016 ! nucleosome organization GO:0034728 138 92 1,000 0,0238513 0,05298822 ! vitamin metabolic process GO:0006766 139 92 1,000 0,0238513 0,05293933 ! regulation of membrane potential GO:0042391 164 93 1,000 0,0243352 0,05396359 ! negative regulation of multicellular organismal process GO:0051241 166 93 1,000 0,0243352 0,05391389 ! female pregnancy GO:0007565 164 94 1,000 0,02482312 0,05494427 ! regulation of T cell activation GO:0050863 158 94 1,000 0,02482312 0,05489377 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 21 10 0,000 0,02560301 0,05656643 ! negative regulation of blood pressure GO:0045776 26 10 0,000 0,02560301 0,05651453 ! negative regulation of lipid biosynthetic process GO:0051055 14 10 0,000 0,02560301 0,05646273 ! regulation of phosphatase activity GO:0010921 28 10 0,000 0,02560301 0,05641103 ! synapsis GO:0007129 13 10 0,000 0,02560301 0,05635941 GO:0070192|chromosome organization involved in meiosis, ! cell volume homeostasis GO:0006884 17 10 0,000 0,02560301 0,0563079 ! N-glycan processing GO:0006491 20 10 0,000 0,02560301 0,05625648 ! regulation of long-term neuronal synaptic plasticity GO:0048169 28 10 0,000 0,02560301 0,05620515 ! SMAD protein nuclear translocation GO:0007184 20 10 0,000 0,02560301 0,05615391 ! regulation of smooth muscle cell migration GO:0014910 27 10 0,000 0,02560301 0,05610277 ! syncytium formation by plasma membrane fusion GO:0000768 16 10 0,000 0,02560301 0,05605172 GO:0007520|myoblast fusion, ! social behavior GO:0035176 24 10 0,000 0,02560301 0,05600076 ! COPI coating of Golgi vesicle GO:0048205 19 10 0,000 0,02560301 0,0559499 GO:0048200|Golgi transport vesicle coating, ! smoothened signaling pathway GO:0007224 16 10 0,000 0,02560301 0,05589913 ! muscarinic acetylcholine receptor signaling pathway GO:0007213 19 10 0,000 0,02560301 0,05584845 ! androgen metabolic process GO:0008209 17 10 0,000 0,02560301 0,05579786 ! phospholipid efflux GO:0033700 16 10 0,000 0,02560301 0,05574737 ! regulation of carbohydrate biosynthetic process GO:0043255 16 10 0,000 0,02560301 0,05569696 ! positive regulation of heart contraction GO:0045823 16 10 0,000 0,02560301 0,05564665 ! lung alveolus development GO:0048286 26 10 0,000 0,02560301 0,05559643 ! pathogenesis GO:0009405 13 10 0,000 0,02560301 0,05554629 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,02560301 0,05549625 ! positive regulation of interferon-gamma biosynthetic process GO:0045078 13 10 0,000 0,02560301 0,0554463 ! negative regulation of striated muscle development GO:0045843 19 10 0,000 0,02560301 0,05539644 ! sphingoid biosynthetic process GO:0046520 21 10 0,000 0,02560301 0,05534667 ! regulation of S phase of mitotic cell cycle GO:0007090 17 10 0,000 0,02560301 0,05529698 ! endoderm development GO:0007492 16 10 0,000 0,02560301 0,05524739 ! positive regulation of survival gene product expression GO:0045885 23 10 0,000 0,02560301 0,05519789 ! arginine catabolic process GO:0006527 13 10 0,000 0,02560301 0,05514847 ! myeloid leukocyte mediated immunity GO:0002444 14 10 0,000 0,02560301 0,05509914 ! proline metabolic process GO:0006560 13 10 0,000 0,02560301 0,0550499 ! glucan biosynthetic process GO:0009250 14 10 0,000 0,02560301 0,05500075 GO:0005978|glycogen biosynthetic process, ! L-serine metabolic process GO:0006563 18 10 0,000 0,02560301 0,05495169 ! polyamine biosynthetic process GO:0006596 12 10 0,000 0,02560301 0,05490271 ! V(D)J recombination GO:0033151 28 10 0,000 0,02560301 0,05485382 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,02560301 0,05480502 ! central nervous system neuron axonogenesis GO:0021955 22 10 0,000 0,02560301 0,0547563 GO:0021952|central nervous system projection neuron axonogenesis, ! regulation of stress fiber formation GO:0051492 30 10 0,000 0,02560301 0,05470767 ! B cell proliferation GO:0042100 18 10 0,000 0,02560301 0,05465913 ! nucleobase biosynthetic process GO:0046112 24 10 0,000 0,02560301 0,05461067 ! regulation of sodium ion transport GO:0002028 21 10 0,000 0,02560301 0,0545623 ! multicellular organism growth GO:0035264 18 10 0,000 0,02560301 0,05451402 ! phagocytosis, engulfment GO:0006911 28 10 0,000 0,02560301 0,05446582 ! neurotransmitter biosynthetic process GO:0042136 16 10 0,000 0,02560301 0,0544177 ! epithelial cell development GO:0002064 20 10 0,000 0,02560301 0,05436967 ! lens development in camera-type eye GO:0002088 16 10 0,000 0,02560301 0,05432173 ! retinoic acid metabolic process GO:0042573 14 10 0,000 0,02560301 0,05427387 ! macroautophagy GO:0016236 17 10 0,000 0,02560301 0,05422609 ! positive regulation of muscle contraction GO:0045933 14 10 0,000 0,02560301 0,0541784 ! positive regulation of translational initiation GO:0045948 11 10 0,000 0,02560301 0,05413079 ! positive regulation vascular endothelial growth factor production GO:0010575 22 10 0,000 0,02560301 0,05408327 ! regulation of smoothened signaling pathway GO:0008589 23 10 0,000 0,02560301 0,05403583 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 26 10 0,000 0,02560301 0,05398847 ! copper ion homeostasis GO:0055070 13 10 0,000 0,02560301 0,05394119 ! regulation of bone resorption GO:0045124 25 10 0,000 0,02560301 0,053894 ! brain morphogenesis GO:0048854 23 10 0,000 0,02560301 0,05384689 ! alpha-beta T cell activation GO:0046631 23 10 0,000 0,02560301 0,05379986 ! negative regulation of axonogenesis GO:0050771 32 10 0,000 0,02560301 0,05375291 ! positive regulation of phagocytosis GO:0050766 13 10 0,000 0,02560301 0,05370605 ! regulation of insulin receptor signaling pathway GO:0046626 19 10 0,000 0,02560301 0,05365927 ! blastoderm segmentation GO:0007350 18 10 0,000 0,02560301 0,05361257 ! response to dsRNA GO:0043331 20 10 0,000 0,02560301 0,05356595 ! DNA ligation GO:0006266 19 10 0,000 0,02560301 0,05351941 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,02560301 0,05347295 ! purine nucleoside triphosphate catabolic process GO:0009146 13 10 0,000 0,02560301 0,05342657 ! melanosome localization GO:0032400 16 10 0,000 0,02560301 0,05338028 ! glycosphingolipid biosynthetic process GO:0006688 15 10 0,000 0,02560301 0,05333406 ! regulation of B cell differentiation GO:0045577 19 10 0,000 0,02560301 0,05328792 ! regulation of protein kinase B signaling cascade GO:0051896 26 10 0,000 0,02560301 0,05324187 ! positive regulation of interleukin-6 production GO:0032755 14 10 0,000 0,02560301 0,05319589 ! positive regulation of Rho GTPase activity GO:0032321 24 10 0,000 0,02560301 0,05314999 ! mRNA cleavage GO:0006379 17 10 0,000 0,02560301 0,05310417 ! protein sumoylation GO:0016925 15 10 0,000 0,02560301 0,05305843 ! hindbrain morphogenesis GO:0021575 19 10 0,000 0,02560301 0,05301277 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,02560301 0,05296719 ! regulation of DNA replication initiation GO:0030174 14 10 0,000 0,02560301 0,05292168 ! cellular metabolic compound salvage GO:0043094 14 10 0,000 0,02560301 0,05287626 ! positive regulation of interleukin-1 beta secretion GO:0050718 13 10 0,000 0,02560301 0,05283091 ! salivary gland development GO:0007431 27 10 0,000 0,02560301 0,05278564 ! prophase GO:0051324 15 10 0,000 0,02560301 0,05274045 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,02560301 0,05269533 ! apical protein localization GO:0045176 15 10 0,000 0,02560301 0,05265029 ! ubiquinone metabolic process GO:0006743 15 10 0,000 0,02560301 0,05260533 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of acute inflammatory response GO:0002675 16 10 0,000 0,02560301 0,05256044 ! positive regulation of leukocyte migration GO:0002687 25 10 0,000 0,02560301 0,05251564 ! midbrain development GO:0030901 13 10 0,000 0,02560301 0,0524709 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,02560301 0,05242625 ! methionine biosynthetic process GO:0009086 19 10 0,000 0,02560301 0,05238167 ! nicotinamide nucleotide biosynthetic process GO:0019359 16 10 0,000 0,02560301 0,05233716 ! quaternary ammonium group transport GO:0015697 21 10 0,000 0,02560301 0,05229273 ! thyroid hormone metabolic process GO:0042403 16 10 0,000 0,02560301 0,05224838 ! negative regulation of BMP signaling pathway GO:0030514 19 10 0,000 0,02560301 0,0522041 ! positive regulation of viral reproduction GO:0048524 18 10 0,000 0,02560301 0,0521599 ! detection of calcium ion GO:0005513 23 10 0,000 0,02560301 0,05211577 ! oocyte development GO:0048599 17 10 0,000 0,02560301 0,05207172 ! establishment of pigment granule localization GO:0051905 18 10 0,000 0,02560301 0,05202774 ! blastocyst formation GO:0001825 17 10 0,000 0,02560301 0,05198383 ! cerebellar cortex development GO:0021695 15 10 0,000 0,02560301 0,05194 ! establishment or maintenance of apical/basal cell polarity GO:0035088 22 10 0,000 0,02560301 0,05189624 ! activation of innate immune response GO:0002218 12 10 0,000 0,02560301 0,05185256 GO:0002758|innate immune response-activating signal transduction, ! natural killer cell mediated immunity GO:0002228 18 10 0,000 0,02560301 0,05180895 GO:0042267|natural killer cell mediated cytotoxicity, ! positive regulation of amine transport GO:0051954 16 10 0,000 0,02560301 0,05176541 ! response to nicotine GO:0035094 20 10 0,000 0,02560301 0,05172195 ! establishment of cell polarity GO:0030010 16 10 0,000 0,02560301 0,05167856 ! negative regulation of immune effector process GO:0002698 20 10 0,000 0,02560301 0,05163524 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 20 10 0,000 0,02560301 0,05159199 ! detection of stimulus GO:0051606 151 96 1,000 0,02581092 0,05196743 ! regulation of DNA metabolic process GO:0051052 178 97 1,000 0,02631076 0,05292951 ! protein ubiquitination GO:0016567 217 97 1,000 0,02631076 0,05288529 ! hormone metabolic process GO:0042445 157 97 1,000 0,02631076 0,05284114 ! negative regulation of muscle development GO:0048635 20 11 0,000 0,02812744 0,05644255 ! respiratory burst GO:0045730 17 11 0,000 0,02812744 0,05639551 ! very-long-chain fatty acid metabolic process GO:0000038 19 11 0,000 0,02812744 0,05634856 ! neuron fate specification GO:0048665 17 11 0,000 0,02812744 0,05630168 ! telencephalon cell migration GO:0022029 20 11 0,000 0,02812744 0,05625488 ! positive regulation of small GTPase mediated signal transduction GO:0051057 19 11 0,000 0,02812744 0,05620815 GO:0046579|positive regulation of Ras protein signal transduction, ! cortical actin cytoskeleton organization GO:0030866 30 11 0,000 0,02812744 0,05616151 ! thyroid gland development GO:0030878 26 11 0,000 0,02812744 0,05611494 ! glycosaminoglycan catabolic process GO:0006027 13 11 0,000 0,02812744 0,05606845 ! Golgi vesicle budding GO:0048194 22 11 0,000 0,02812744 0,05602203 ! response to pain GO:0048265 24 11 0,000 0,02812744 0,05597569 ! detection of mechanical stimulus GO:0050982 22 11 0,000 0,02812744 0,05592943 ! T cell proliferation GO:0042098 26 11 0,000 0,02812744 0,05588325 ! blood vessel remodeling GO:0001974 29 11 0,000 0,02812744 0,05583714 ! negative regulation of cell-matrix adhesion GO:0001953 36 11 0,000 0,02812744 0,05579111 GO:0010812|negative regulation of cell-substrate adhesion, ! positive regulation of endothelial cell proliferation GO:0001938 22 11 0,000 0,02812744 0,05574515 ! bone resorption GO:0045453 16 11 0,000 0,02812744 0,05569927 ! ventral spinal cord development GO:0021517 21 11 0,000 0,02812744 0,05565347 ! negative regulation of proteolysis GO:0045861 25 11 0,000 0,02812744 0,05560774 ! regulation of catecholamine secretion GO:0050433 20 11 0,000 0,02812744 0,05556208 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 18 11 0,000 0,02812744 0,0555165 ! melanocyte differentiation GO:0030318 21 11 0,000 0,02812744 0,055471 GO:0050931|pigment cell differentiation, ! syncytium formation GO:0006949 18 11 0,000 0,02812744 0,05542557 ! telomere maintenance via telomerase GO:0007004 21 11 0,000 0,02812744 0,05538021 GO:0010833|telomere maintenance via telomere lengthening, ! indolalkylamine metabolic process GO:0006586 17 11 0,000 0,02812744 0,05533493 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! regulation of Cdc42 protein signal transduction GO:0032489 21 11 0,000 0,02812744 0,05528972 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of intracellular pH GO:0051453 19 11 0,000 0,02812744 0,05524458 ! lipid digestion GO:0044241 18 11 0,000 0,02812744 0,05519952 ! substrate-bound cell migration GO:0006929 13 11 0,000 0,02812744 0,05515454 ! UV protection GO:0009650 19 11 0,000 0,02812744 0,05510962 ! adult heart development GO:0007512 14 11 0,000 0,02812744 0,05506478 ! chondrocyte differentiation GO:0002062 24 11 0,000 0,02812744 0,05502001 ! regulation of lipoprotein lipase activity GO:0051004 23 11 0,000 0,02812744 0,05497532 ! temperature homeostasis GO:0001659 17 11 0,000 0,02812744 0,05493069 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 23 11 0,000 0,02812744 0,05488614 ! negative regulation of ossification GO:0030279 26 11 0,000 0,02812744 0,05484167 ! regulation of vascular endothelial growth factor production GO:0010574 23 11 0,000 0,02812744 0,05479726 ! positive regulation of peptide secretion GO:0002793 22 11 0,000 0,02812744 0,05475292 ! regulation of organ growth GO:0046620 13 11 0,000 0,02812744 0,05470866 ! pigment granule localization GO:0051875 20 11 0,000 0,02812744 0,05466447 ! positive regulation of T cell mediated immunity GO:0002711 24 11 0,000 0,02812744 0,05462035 ! vasoconstriction GO:0042310 18 11 0,000 0,02812744 0,0545763 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 20 11 0,000 0,02812744 0,05453232 ! embryonic axis specification GO:0000578 18 11 0,000 0,02812744 0,05448842 ! sphingomyelin metabolic process GO:0006684 15 11 0,000 0,02812744 0,05444458 ! snRNA metabolic process GO:0016073 24 11 0,000 0,02812744 0,05440082 GO:0016180|snRNA processing, ! purine ribonucleotide catabolic process GO:0009154 17 11 0,000 0,02812744 0,05435712 ! nitric oxide metabolic process GO:0046209 15 11 0,000 0,02812744 0,0543135 GO:0006809|nitric oxide biosynthetic process, ! DNA methylation GO:0006306 19 11 0,000 0,02812744 0,05426994 GO:0006305|DNA alkylation, ! negative regulation of tumor necrosis factor production GO:0032720 15 11 0,000 0,02812744 0,05422645 ! zymogen activation GO:0031638 15 11 0,000 0,02812744 0,05418304 ! positive regulation of interleukin-1 secretion GO:0050716 14 11 0,000 0,02812744 0,05413969 ! nucleosome positioning GO:0016584 15 11 0,000 0,02812744 0,05409642 ! regulation of isotype switching GO:0045191 22 11 0,000 0,02812744 0,05405321 ! regulation of interleukin-1 beta secretion GO:0050706 15 11 0,000 0,02812744 0,05401007 ! glutathione biosynthetic process GO:0006750 13 11 0,000 0,02812744 0,053967 ! regulation of leukocyte migration GO:0002685 26 11 0,000 0,02812744 0,053924 ! acid secretion GO:0046717 18 11 0,000 0,02812744 0,05388106 ! regulation of osteoclast differentiation GO:0045670 17 11 0,000 0,02812744 0,0538382 ! positive regulation of neuron differentiation GO:0045666 19 11 0,000 0,02812744 0,0537954 ! nitric oxide mediated signal transduction GO:0007263 23 11 0,000 0,02812744 0,05375267 ! regulation of T-helper 2 cell differentiation GO:0045628 20 11 0,000 0,02812744 0,05371001 ! oocyte differentiation GO:0009994 18 11 0,000 0,02812744 0,05366742 ! somatic diversification of immunoglobulins during immune response GO:0002208 22 11 0,000 0,02812744 0,05362489 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! thymus development GO:0048538 27 11 0,000 0,02812744 0,05358243 ! cholesterol efflux GO:0033344 19 11 0,000 0,02812744 0,05354004 ! anterior/posterior axis specification GO:0009948 18 11 0,000 0,02812744 0,05349772 ! positive regulation of JNK cascade GO:0046330 23 11 0,000 0,02812744 0,05345546 ! negative regulation of glucose import GO:0046325 17 11 0,000 0,02812744 0,05341327 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 25 11 0,000 0,02812744 0,05337115 ! embryonic gut development GO:0048566 15 11 0,000 0,02812744 0,05332909 ! regulation of organic acid transport GO:0032890 18 11 0,000 0,02812744 0,0532871 ! regulation of actin filament bundle formation GO:0032231 33 11 0,000 0,02812744 0,05324517 ! defense response to Gram-positive bacterium GO:0050830 13 11 0,000 0,02812744 0,05320331 ! defense response to fungus GO:0050832 13 11 0,000 0,02812744 0,05316152 ! developmental induction GO:0031128 19 11 0,000 0,02812744 0,05311979 GO:0045168|cell-cell signaling involved in cell fate specification, ! lysogeny GO:0030069 21 11 0,000 0,02812744 0,05307813 GO:0019047|provirus integration, ! prepulse inhibition GO:0060134 18 11 0,000 0,02812744 0,05303653 ! T cell receptor signaling pathway GO:0050852 23 11 0,000 0,02812744 0,052995 ! sequestering of metal ion GO:0051238 14 11 0,000 0,02812744 0,05295353 ! lamellipodium assembly GO:0030032 20 11 0,000 0,02812744 0,05291213 ! regulation of synapse organization GO:0050807 17 11 0,000 0,02812744 0,05287079 ! negative regulation of cell projection organization GO:0031345 37 12 0,000 0,03064541 0,05755883 ! regulation of membrane protein ectodomain proteolysis GO:0051043 22 12 0,000 0,03064541 0,05751393 ! positive regulation of blood pressure GO:0045777 17 12 0,000 0,03064541 0,0574691 ! cortical cytoskeleton organization GO:0030865 31 12 0,000 0,03064541 0,05742434 ! folic acid and derivative biosynthetic process GO:0009396 21 12 0,000 0,03064541 0,05737965 ! cartilage condensation GO:0001502 20 12 0,000 0,03064541 0,05733504 ! regulation of positive chemotaxis GO:0050926 19 12 0,000 0,03064541 0,05729049 GO:0050927|positive regulation of positive chemotaxis, ! mating GO:0007618 17 12 0,000 0,03064541 0,05724601 ! protein complex disassembly GO:0043241 27 12 0,000 0,03064541 0,05720159 GO:0043624|cellular protein complex disassembly, ! dopamine receptor signaling pathway GO:0007212 28 12 0,000 0,03064541 0,05715725 ! cytokine biosynthetic process GO:0042089 21 12 0,000 0,03064541 0,05711298 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 27 12 0,000 0,03064541 0,05706877 ! positive regulation of cell growth GO:0030307 22 12 0,000 0,03064541 0,05702464 ! regulation of interferon-gamma biosynthetic process GO:0045072 16 12 0,000 0,03064541 0,05698057 ! regulation of exit from mitosis GO:0007096 17 12 0,000 0,03064541 0,05693657 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 24 12 0,000 0,03064541 0,05689264 ! glycolipid biosynthetic process GO:0009247 17 12 0,000 0,03064541 0,05684877 ! drug transport GO:0015893 16 12 0,000 0,03064541 0,05680497 ! nucleotide-sugar metabolic process GO:0009225 19 12 0,000 0,03064541 0,05676124 ! oligodendrocyte differentiation GO:0048709 16 12 0,000 0,03064541 0,05671758 ! tyrosine metabolic process GO:0006570 16 12 0,000 0,03064541 0,05667399 ! polyamine metabolic process GO:0006595 17 12 0,000 0,03064541 0,05663046 ! focal adhesion formation GO:0048041 35 12 0,000 0,03064541 0,056587 ! mitotic spindle organization GO:0007052 21 12 0,000 0,03064541 0,0565436 ! negative regulation of endothelial cell migration GO:0010596 25 12 0,000 0,03064541 0,05650027 ! forebrain cell migration GO:0021885 21 12 0,000 0,03064541 0,05645701 ! asymmetric protein localization GO:0008105 20 12 0,000 0,03064541 0,05641381 ! membrane protein proteolysis GO:0033619 25 12 0,000 0,03064541 0,05637068 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 16 12 0,000 0,03064541 0,05632762 ! fear response GO:0042596 26 12 0,000 0,03064541 0,05628462 ! monoamine transport GO:0015844 18 12 0,000 0,03064541 0,05624169 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,03064541 0,05619882 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! L-glutamate transport GO:0015813 22 12 0,000 0,03064541 0,05615602 GO:0015800|acidic amino acid transport, ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 24 12 0,000 0,03064541 0,05611328 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 19 12 0,000 0,03064541 0,05607061 ! acyl-CoA metabolic process GO:0006637 21 12 0,000 0,03064541 0,05602801 ! protein targeting to peroxisome GO:0006625 23 12 0,000 0,03064541 0,05598546 ! protein homotetramerization GO:0051289 21 12 0,000 0,03064541 0,05594299 ! negative regulation of myeloid leukocyte differentiation GO:0002762 16 12 0,000 0,03064541 0,05590057 ! regulation of phagocytosis GO:0050764 16 12 0,000 0,03064541 0,05585822 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,03064541 0,05581594 ! synaptic vesicle exocytosis GO:0016079 19 12 0,000 0,03064541 0,05577372 ! regulation of interleukin-8 production GO:0032677 20 12 0,000 0,03064541 0,05573156 ! regulation of interleukin-12 production GO:0032655 19 12 0,000 0,03064541 0,05568947 ! cranial nerve development GO:0021545 20 12 0,000 0,03064541 0,05564744 ! fucose catabolic process GO:0019317 22 12 0,000 0,03064541 0,05560547 GO:0042355|L-fucose catabolic process, ! immunoglobulin production during immune response GO:0002381 23 12 0,000 0,03064541 0,05556357 ! histone methylation GO:0016571 26 12 0,000 0,03064541 0,05552173 ! mRNA polyadenylation GO:0006378 23 12 0,000 0,03064541 0,05547995 ! autonomic nervous system development GO:0048483 24 12 0,000 0,03064541 0,05543824 ! gland morphogenesis GO:0022612 29 12 0,000 0,03064541 0,05539659 ! regulation of hormone metabolic process GO:0032350 26 12 0,000 0,03064541 0,055355 ! T cell homeostasis GO:0043029 25 12 0,000 0,03064541 0,05531347 ! regulation of interleukin-1 secretion GO:0050704 16 12 0,000 0,03064541 0,05527201 ! aromatic amino acid family catabolic process GO:0009074 18 12 0,000 0,03064541 0,0552306 ! spleen development GO:0048536 22 12 0,000 0,03064541 0,05518926 ! digestive tract morphogenesis GO:0048546 26 12 0,000 0,03064541 0,05514798 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! biogenic amine catabolic process GO:0042402 23 12 0,000 0,03064541 0,05510677 ! leukocyte mediated cytotoxicity GO:0001909 26 12 0,000 0,03064541 0,05506561 ! regulation of RNA splicing GO:0043484 20 12 0,000 0,03064541 0,05502452 ! quinone cofactor metabolic process GO:0042375 18 12 0,000 0,03064541 0,05498349 ! regulation of blood vessel endothelial cell migration GO:0043535 37 12 0,000 0,03064541 0,05494252 ! positive regulation of calcium-mediated signaling GO:0050850 24 12 0,000 0,03064541 0,0549016 ! response to cold GO:0009409 17 12 0,000 0,03064541 0,05486076 ! regulation of synapse structure and activity GO:0050803 18 12 0,000 0,03064541 0,05481997 ! regulation of steroid biosynthetic process GO:0050810 17 12 0,000 0,03064541 0,05477924 ! cGMP metabolic process GO:0046068 18 13 0,000 0,03315694 0,05922465 GO:0006182|cGMP biosynthetic process, ! 'de novo' protein folding GO:0006458 25 13 0,000 0,03315694 0,05918071 ! regulation of chemokine production GO:0032642 18 13 0,000 0,03315694 0,05913684 ! peroxisomal transport GO:0043574 24 13 0,000 0,03315694 0,05909304 ! regulation of cell-cell adhesion GO:0022407 33 13 0,000 0,03315694 0,0590493 ! lipid localization GO:0010876 28 13 0,000 0,03315694 0,05900562 GO:0019915|lipid storage, ! negative regulation of transcription factor import into nucleus GO:0042992 29 13 0,000 0,03315694 0,05896201 ! organelle fusion GO:0048284 32 13 0,000 0,03315694 0,05891846 ! positive regulation of lipid metabolic process GO:0045834 25 13 0,000 0,03315694 0,05887498 ! negative regulation of lipid metabolic process GO:0045833 19 13 0,000 0,03315694 0,05883156 ! pseudouridine synthesis GO:0001522 17 13 0,000 0,03315694 0,05878821 ! endocrine pancreas development GO:0031018 22 13 0,000 0,03315694 0,05874492 ! two-component signal transduction system (phosphorelay) GO:0000160 17 13 0,000 0,03315694 0,05870169 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 23 13 0,000 0,03315694 0,05865853 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 25 13 0,000 0,03315694 0,05861543 ! regulation of skeletal muscle fiber development GO:0048742 32 13 0,000 0,03315694 0,05857239 ! methionine metabolic process GO:0006555 27 13 0,000 0,03315694 0,05852942 ! plasma membrane organization GO:0007009 24 13 0,000 0,03315694 0,05848651 ! deoxyribonucleotide catabolic process GO:0009264 19 13 0,000 0,03315694 0,05844366 ! ribonucleotide catabolic process GO:0009261 20 13 0,000 0,03315694 0,05840088 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 27 13 0,000 0,03315694 0,05835816 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! Golgi organization GO:0007030 24 13 0,000 0,03315694 0,0583155 ! cell-cell junction assembly GO:0007043 27 13 0,000 0,03315694 0,0582729 ! response to X-ray GO:0010165 25 13 0,000 0,03315694 0,05823037 ! cytokine metabolic process GO:0042107 22 13 0,000 0,03315694 0,05818789 ! exocrine system development GO:0035272 32 13 0,000 0,03315694 0,05814548 ! negative regulation of mitotic cell cycle GO:0045930 33 13 0,000 0,03315694 0,05810313 ! heparan sulfate proteoglycan metabolic process GO:0030201 28 13 0,000 0,03315694 0,05806084 ! cotranslational protein targeting to membrane GO:0006613 24 13 0,000 0,03315694 0,05801862 ! regulation of cytokine production during immune response GO:0002718 23 13 0,000 0,03315694 0,05797645 ! regulation of natural killer cell mediated immunity GO:0002715 27 13 0,000 0,03315694 0,05793435 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 21 13 0,000 0,03315694 0,05789231 ! RNA-dependent DNA replication GO:0006278 23 13 0,000 0,03315694 0,05785033 ! nucleoside triphosphate catabolic process GO:0009143 21 13 0,000 0,03315694 0,05780841 ! cell wall macromolecule catabolic process GO:0016998 14 13 0,000 0,03315694 0,05776655 ! regulation of cellular pH GO:0030641 22 13 0,000 0,03315694 0,05772475 ! ribosomal large subunit biogenesis GO:0042273 13 13 0,000 0,03315694 0,05768301 ! ribosome assembly GO:0042255 17 13 0,000 0,03315694 0,05764133 ! gastrulation with mouth forming second GO:0001702 25 13 0,000 0,03315694 0,05759971 ! positive regulation of Ras GTPase activity GO:0032320 35 13 0,000 0,03315694 0,05755815 ! chromatin silencing GO:0006342 26 13 0,000 0,03315694 0,05751665 ! regulation of acute inflammatory response GO:0002673 21 13 0,000 0,03315694 0,05747522 ! regulation of epidermis development GO:0045682 19 13 0,000 0,03315694 0,05743384 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 0,000 0,03315694 0,05739252 ! serine family amino acid biosynthetic process GO:0009070 17 13 0,000 0,03315694 0,05735126 ! pyridine nucleotide biosynthetic process GO:0019363 19 13 0,000 0,03315694 0,05731006 ! regulation of mRNA stability GO:0043488 31 13 0,000 0,03315694 0,05726892 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 34 13 0,000 0,03315694 0,05722783 ! positive regulation of homeostatic process GO:0032846 21 13 0,000 0,03315694 0,05718681 ! mRNA 3'-end processing GO:0031124 24 13 0,000 0,03315694 0,05714585 ! regulation of calcium-mediated signaling GO:0050848 25 13 0,000 0,03315694 0,05710494 ! embryonic placenta development GO:0001892 23 13 0,000 0,03315694 0,05706409 ! positive regulation of protein polymerization GO:0032273 25 13 0,000 0,03315694 0,0570233 ! insulin secretion GO:0030073 23 13 0,000 0,03315694 0,05698257 ! actin filament polymerization GO:0030041 24 13 0,000 0,03315694 0,0569419 ! cytoplasmic sequestering of protein GO:0051220 24 13 0,000 0,03315694 0,05690128 ! acrosome reaction GO:0007340 18 13 0,000 0,03315694 0,05686073 ! rRNA transcription GO:0009303 25 14 0,000 0,03566205 0,06111317 ! lactation GO:0007595 26 14 0,000 0,03566205 0,06106967 ! reproductive cellular process GO:0048610 20 14 0,000 0,03566205 0,06102624 ! tRNA modification GO:0006400 20 14 0,000 0,03566205 0,06098286 ! pteridine and derivative biosynthetic process GO:0042559 19 14 0,000 0,03566205 0,06093955 ! regulation of S phase GO:0033261 23 14 0,000 0,03566205 0,0608963 ! water transport GO:0006833 21 14 0,000 0,03566205 0,06085311 GO:0042044|fluid transport, ! myotube differentiation GO:0014902 25 14 0,000 0,03566205 0,06080999 ! non-recombinational repair GO:0000726 25 14 0,000 0,03566205 0,06076692 GO:0006303|double-strand break repair via nonhomologous end joining, ! positive regulation of GTPase activity GO:0043547 36 14 0,000 0,03566205 0,06072391 ! vesicle targeting, to, from or within Golgi GO:0048199 25 14 0,000 0,03566205 0,06068097 ! retina development in camera-type eye GO:0060041 27 14 0,000 0,03566205 0,06063808 ! hair follicle morphogenesis GO:0031069 26 14 0,000 0,03566205 0,06059526 ! RNA polyadenylation GO:0043631 30 14 0,000 0,03566205 0,0605525 ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 20 14 0,000 0,03566205 0,06050979 ! palate development GO:0060021 31 14 0,000 0,03566205 0,06046715 ! negative regulation of protein amino acid phosphorylation GO:0001933 32 14 0,000 0,03566205 0,06042457 ! regulated secretory pathway GO:0045055 23 14 0,000 0,03566205 0,06038205 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 19 14 0,000 0,03566205 0,06033958 ! arginine metabolic process GO:0006525 17 14 0,000 0,03566205 0,06029718 ! regulation of heart rate GO:0002027 24 14 0,000 0,03566205 0,06025484 ! organic alcohol transport GO:0015850 29 14 0,000 0,03566205 0,06021255 ! actin cytoskeleton reorganization GO:0031532 33 14 0,000 0,03566205 0,06017033 ! negative regulation of caspase activity GO:0043154 22 14 0,000 0,03566205 0,06012816 ! branching involved in ureteric bud morphogenesis GO:0001658 28 14 0,000 0,03566205 0,06008606 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 30 14 0,000 0,03566205 0,06004401 ! neutral amino acid transport GO:0015804 26 14 0,000 0,03566205 0,06000202 ! L-amino acid transport GO:0015807 30 14 0,000 0,03566205 0,05996009 ! stem cell development GO:0048864 43 14 0,000 0,03566205 0,05991822 GO:0019827|stem cell maintenance, ! negative regulation of protein import into nucleus GO:0042308 30 14 0,000 0,03566205 0,05987641 ! T cell differentiation in the thymus GO:0033077 31 14 0,000 0,03566205 0,05983465 ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 0,000 0,03566205 0,05979295 ! cerebellum development GO:0021549 21 14 0,000 0,03566205 0,05975132 ! regulation of T-helper 2 type immune response GO:0002828 24 14 0,000 0,03566205 0,05970974 ! negative regulation of protein secretion GO:0050709 28 14 0,000 0,03566205 0,05966821 ! response to gamma radiation GO:0010332 28 14 0,000 0,03566205 0,05962675 ! positive regulation of bone mineralization GO:0030501 29 14 0,000 0,03566205 0,05958534 ! cofactor transport GO:0051181 26 14 0,000 0,03566205 0,05954399 ! NADP metabolic process GO:0006739 24 14 0,000 0,03566205 0,0595027 ! regulation of erythrocyte differentiation GO:0045646 44 14 0,000 0,03566205 0,05946146 ! protein-chromophore linkage GO:0018298 19 14 0,000 0,03566205 0,05942028 ! intestinal absorption GO:0050892 25 14 0,000 0,03566205 0,05937916 ! oxygen transport GO:0015671 21 14 0,000 0,03566205 0,0593381 ! catecholamine biosynthetic process GO:0042423 30 14 0,000 0,03566205 0,05929709 ! male genitalia development GO:0030539 24 14 0,000 0,03566205 0,05925614 ! regulation of RNA stability GO:0043487 32 14 0,000 0,03566205 0,05921524 ! regulation of axon extension GO:0030516 37 14 0,000 0,03566205 0,05917441 ! release of cytochrome c from mitochondria GO:0001836 30 14 0,000 0,03566205 0,05913362 ! cell wall macromolecule metabolic process GO:0044036 15 14 0,000 0,03566205 0,0590929 ! regulation of skeletal muscle tissue development GO:0048641 35 15 0,000 0,03816075 0,06318979 ! ER-associated protein catabolic process GO:0030433 24 15 0,000 0,03816075 0,06314633 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! positive regulation of cell size GO:0045793 27 15 0,000 0,03816075 0,06310293 ! superoxide anion generation GO:0042554 20 15 0,000 0,03816075 0,06305959 ! negative regulation of bone remodeling GO:0046851 33 15 0,000 0,03816075 0,06301631 ! embryonic hindlimb morphogenesis GO:0035116 33 15 0,000 0,03816075 0,06297309 ! phospholipid catabolic process GO:0009395 22 15 0,000 0,03816075 0,06292993 ! copper ion transport GO:0006825 20 15 0,000 0,03816075 0,06288682 ! heterophilic cell adhesion GO:0007157 39 15 0,000 0,03816075 0,06284378 ! cardiac muscle contraction GO:0060048 26 15 0,000 0,03816075 0,06280079 ! sulfate transport GO:0008272 23 15 0,000 0,03816075 0,06275787 ! response to cAMP GO:0051591 22 15 0,000 0,03816075 0,062715 ! regulation of excitatory postsynaptic membrane potential GO:0060079 27 15 0,000 0,03816075 0,06267219 ! negative regulation of cytokine biosynthetic process GO:0042036 23 15 0,000 0,03816075 0,06262944 ! ciliary or flagellar motility GO:0001539 20 15 0,000 0,03816075 0,06258675 ! regulation of transmembrane transporter activity GO:0022898 27 15 0,000 0,03816075 0,06254412 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! isoprenoid biosynthetic process GO:0008299 32 15 0,000 0,03816075 0,06250154 ! response to hexose stimulus GO:0009746 22 15 0,000 0,03816075 0,06245902 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! pyrimidine ribonucleotide metabolic process GO:0009218 21 15 0,000 0,03816075 0,06241656 ! glycoprotein catabolic process GO:0006516 26 15 0,000 0,03816075 0,06237416 ! pituitary gland development GO:0021983 29 15 0,000 0,03816075 0,06233181 ! vesicle coating GO:0006901 33 15 0,000 0,03816075 0,06228953 ! regulation of the force of heart contraction GO:0002026 26 15 0,000 0,03816075 0,0622473 ! preassembly of GPI anchor in ER membrane GO:0016254 25 15 0,000 0,03816075 0,06220512 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 28 15 0,000 0,03816075 0,06216301 ! regulation of exocytosis GO:0017157 22 15 0,000 0,03816075 0,06212095 ! G1/S transition checkpoint GO:0031575 40 15 0,000 0,03816075 0,06207895 ! intermediate filament cytoskeleton organization GO:0045104 31 15 0,000 0,03816075 0,062037 ! positive regulation of axonogenesis GO:0050772 28 15 0,000 0,03816075 0,06199511 ! positive regulation of biomineral formation GO:0070169 30 15 0,000 0,03816075 0,06195328 ! regulation of vasodilation GO:0042312 26 15 0,000 0,03816075 0,0619115 ! regulation of T cell mediated immunity GO:0002709 33 15 0,000 0,03816075 0,06186979 ! histone deacetylation GO:0016575 20 15 0,000 0,03816075 0,06182812 ! mRNA splice site selection GO:0006376 38 15 0,000 0,03816075 0,06178651 ! tissue regeneration GO:0042246 26 15 0,000 0,03816075 0,06174496 ! positive regulation of oxidoreductase activity GO:0051353 22 15 0,000 0,03816075 0,06170347 ! water homeostasis GO:0030104 27 15 0,000 0,03816075 0,06166203 ! synaptic transmission, cholinergic GO:0007271 24 15 0,000 0,03816075 0,06162064 ! muscle maintenance GO:0046716 26 15 0,000 0,03816075 0,06157932 ! regulation of T-helper cell differentiation GO:0045622 26 15 0,000 0,03816075 0,06153804 ! regulation of ATPase activity GO:0043462 21 15 0,000 0,03816075 0,06149683 ! dopamine metabolic process GO:0042417 35 15 0,000 0,03816075 0,06145566 ! heme biosynthetic process GO:0006783 29 15 0,000 0,03816075 0,06141456 ! cell killing GO:0001906 29 15 0,000 0,03816075 0,0613735 ! lymphocyte homeostasis GO:0002260 30 15 0,000 0,03816075 0,06133251 ! detection of bacterium GO:0016045 18 15 0,000 0,03816075 0,06129156 ! positive regulation of calcium ion transport GO:0051928 19 15 0,000 0,03816075 0,06125067 ! L-fucose metabolic process GO:0042354 30 15 0,000 0,03816075 0,06120984 ! regulation of NF-kappaB import into nucleus GO:0042345 29 15 0,000 0,03816075 0,06116906 ! peptide hormone processing GO:0016486 23 15 0,000 0,03816075 0,06112834 ! regulation of protein ubiquitination GO:0031396 25 16 0,000 0,04065306 0,06507735 ! G1 phase of mitotic cell cycle GO:0000080 35 16 0,000 0,04065306 0,06503408 ! sulfur amino acid biosynthetic process GO:0000097 28 16 0,000 0,04065306 0,06499087 ! dicarboxylic acid transport GO:0006835 38 16 0,000 0,04065306 0,06494771 ! embryonic forelimb morphogenesis GO:0035115 28 16 0,000 0,04065306 0,06490461 ! bone remodeling GO:0046849 27 16 0,000 0,04065306 0,06486157 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 21 16 0,000 0,04065306 0,06481859 ! regulation of neurotransmitter secretion GO:0046928 33 16 0,000 0,04065306 0,06477567 ! positive regulation of ion transport GO:0043270 21 16 0,000 0,04065306 0,0647328 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 32 16 0,000 0,04065306 0,06468998 ! startle response GO:0001964 28 16 0,000 0,04065306 0,06464723 ! auditory receptor cell differentiation GO:0042491 32 16 0,000 0,04065306 0,06460453 ! negative regulation of endothelial cell proliferation GO:0001937 36 16 0,000 0,04065306 0,06456188 ! regulation of interleukin-2 biosynthetic process GO:0045076 28 16 0,000 0,04065306 0,0645193 ! regulation of defense response to virus GO:0050688 27 16 0,000 0,04065306 0,06447677 ! induction of apoptosis via death domain receptors GO:0008625 20 16 0,000 0,04065306 0,06443429 ! protein polyubiquitination GO:0000209 34 16 0,000 0,04065306 0,06439187 ! glutamate metabolic process GO:0006536 22 16 0,000 0,04065306 0,06434951 ! complement activation, alternative pathway GO:0006957 18 16 0,000 0,04065306 0,0643072 ! response to osmotic stress GO:0006970 25 16 0,000 0,04065306 0,06426495 ! negative regulation of microtubule depolymerization GO:0007026 46 16 0,000 0,04065306 0,06422275 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 26 16 0,000 0,04065306 0,06418061 ! fructose metabolic process GO:0006000 25 16 0,000 0,04065306 0,06413853 ! purine nucleoside monophosphate metabolic process GO:0009126 27 16 0,000 0,04065306 0,0640965 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! regulation of dephosphorylation GO:0035303 43 16 0,000 0,04065306 0,06405452 ! intermediate filament-based process GO:0045103 32 16 0,000 0,04065306 0,0640126 ! NLS-bearing substrate import into nucleus GO:0006607 46 16 0,000 0,04065306 0,06397074 ! negative regulation of immune response GO:0050777 35 16 0,000 0,04065306 0,06392892 ! axon cargo transport GO:0008088 43 16 0,000 0,04065306 0,06388717 ! embryonic digit morphogenesis GO:0042733 34 16 0,000 0,04065306 0,06384547 ! nucleotide-excision repair, DNA gap filling GO:0006297 24 16 0,000 0,04065306 0,06380382 ! DNA replication initiation GO:0006270 27 16 0,000 0,04065306 0,06376223 ! neuron recognition GO:0008038 35 16 0,000 0,04065306 0,06372069 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 27 16 0,000 0,04065306 0,0636792 ! cellular amino acid derivative catabolic process GO:0042219 29 16 0,000 0,04065306 0,06363777 ! positive regulation of cytokine secretion GO:0050715 26 16 0,000 0,04065306 0,06359639 ! negative regulation of inflammatory response GO:0050728 22 16 0,000 0,04065306 0,06355507 ! negative regulation of tissue remodeling GO:0034104 36 16 0,000 0,04065306 0,0635138 ! sphingolipid catabolic process GO:0030149 27 16 0,000 0,04065306 0,06347259 GO:0046466|membrane lipid catabolic process, ! neuromuscular synaptic transmission GO:0007274 33 16 0,000 0,04065306 0,06343142 ! glutamine family amino acid biosynthetic process GO:0009084 19 16 0,000 0,04065306 0,06339031 ! aspartate family amino acid biosynthetic process GO:0009067 27 16 0,000 0,04065306 0,06334926 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 30 16 0,000 0,04065306 0,06330826 ! positive regulation of neuron apoptosis GO:0043525 32 16 0,000 0,04065306 0,06326731 ! defense response to virus GO:0051607 37 16 0,000 0,04065306 0,06322641 ! positive regulation of cell killing GO:0031343 32 17 0,000 0,04313899 0,06704936 ! positive regulation of protein complex assembly GO:0031334 32 17 0,000 0,04313899 0,06700607 ! metencephalon development GO:0022037 30 17 0,000 0,04313899 0,06696284 ! negative regulation of hormone secretion GO:0046888 25 17 0,000 0,04313899 0,06691967 ! negative regulation of cell cycle process GO:0010948 32 17 0,000 0,04313899 0,06687655 ! 2'-deoxyribonucleotide metabolic process GO:0009394 25 17 0,000 0,04313899 0,06683349 GO:0019692|deoxyribose phosphate metabolic process, ! phosphatidylcholine metabolic process GO:0046470 24 17 0,000 0,04313899 0,06679048 ! signal complex assembly GO:0007172 41 17 0,000 0,04313899 0,06674753 ! endothelial cell migration GO:0043542 28 17 0,000 0,04313899 0,06670463 ! inositol metabolic process GO:0006020 28 17 0,000 0,04313899 0,06666179 ! gene silencing by RNA GO:0031047 36 17 0,000 0,04313899 0,066619 ! positive regulation of receptor-mediated endocytosis GO:0048260 21 17 0,000 0,04313899 0,06657627 ! glial cell development GO:0021782 27 17 0,000 0,04313899 0,0665336 ! regulation of muscle cell differentiation GO:0051147 33 17 0,000 0,04313899 0,06649097 ! adult walking behavior GO:0007628 33 17 0,000 0,04313899 0,06644841 ! negative regulation of peptidase activity GO:0010466 27 17 0,000 0,04313899 0,06640589 ! heart looping GO:0001947 30 17 0,000 0,04313899 0,06636343 ! negative regulation of gene expression, epigenetic GO:0045814 35 17 0,000 0,04313899 0,06632103 ! regulation of viral genome replication GO:0045069 28 17 0,000 0,04313899 0,06627868 ! myoblast differentiation GO:0045445 45 17 0,000 0,04313899 0,06623638 ! cell differentiation in spinal cord GO:0021515 30 17 0,000 0,04313899 0,06619414 ! platelet-derived growth factor receptor signaling pathway GO:0048008 28 17 0,000 0,04313899 0,06615195 ! regulation of survival gene product expression GO:0045884 33 17 0,000 0,04313899 0,06610981 ! cardiac muscle tissue development GO:0048738 31 17 0,000 0,04313899 0,06606773 ! regulation of striated muscle contraction GO:0006942 21 17 0,000 0,04313899 0,06602571 ! glycine metabolic process GO:0006544 28 17 0,000 0,04313899 0,06598373 ! pyrimidine ribonucleoside metabolic process GO:0046131 21 17 0,000 0,04313899 0,06594181 ! NAD metabolic process GO:0019674 29 17 0,000 0,04313899 0,06589994 ! membrane budding GO:0006900 37 17 0,000 0,04313899 0,06585813 ! DNA integration GO:0015074 29 17 0,000 0,04313899 0,06581637 ! negative regulation of protein catabolic process GO:0042177 40 17 0,000 0,04313899 0,06577466 ! regulation of protein binding GO:0043393 33 17 0,000 0,04313899 0,065733 ! nucleobase metabolic process GO:0009112 37 17 0,000 0,04313899 0,0656914 ! DNA unwinding during replication GO:0006268 27 17 0,000 0,04313899 0,06564985 ! genitalia development GO:0048806 30 17 0,000 0,04313899 0,06560835 ! DNA fragmentation involved in apoptosis GO:0006309 25 17 0,000 0,04313899 0,0655669 ! regulation of immunoglobulin mediated immune response GO:0002889 32 17 0,000 0,04313899 0,06552551 GO:0002712|regulation of B cell mediated immunity, ! neural crest cell migration GO:0001755 37 17 0,000 0,04313899 0,06548417 ! neutrophil chemotaxis GO:0030593 27 17 0,000 0,04313899 0,06544288 ! negative regulation of blood coagulation GO:0030195 24 17 0,000 0,04313899 0,06540164 ! folic acid and derivative metabolic process GO:0006760 33 17 0,000 0,04313899 0,06536046 ! steroid catabolic process GO:0006706 31 17 0,000 0,04313899 0,06531933 ! activation of NF-kappaB-inducing kinase activity GO:0007250 26 17 0,000 0,04313899 0,06527824 ! branched chain family amino acid metabolic process GO:0009081 33 17 0,000 0,04313899 0,06523721 ! gas transport GO:0015669 25 17 0,000 0,04313899 0,06519624 ! organic cation transport GO:0015695 31 17 0,000 0,04313899 0,06515531 ! aromatic compound biosynthetic process GO:0019438 24 17 0,000 0,04313899 0,06511443 ! negative regulation of homeostatic process GO:0032845 33 17 0,000 0,04313899 0,06507361 ! RNA 3'-end processing GO:0031123 34 17 0,000 0,04313899 0,06503284 ! antigen receptor-mediated signaling pathway GO:0050851 33 17 0,000 0,04313899 0,06499212 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 48 17 0,000 0,04313899 0,06495144 ! oligosaccharide metabolic process GO:0009311 34 18 0,000 0,04561856 0,06864182 ! neuron maturation GO:0042551 42 18 0,000 0,04561856 0,06859891 ! positive regulation of anti-apoptosis GO:0045768 39 18 0,000 0,04561856 0,06855607 ! regulation of lipid biosynthetic process GO:0046890 25 18 0,000 0,04561856 0,06851327 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 33 18 0,000 0,04561856 0,06847053 ! aminoglycan catabolic process GO:0006026 22 18 0,000 0,04561856 0,06842784 ! memory GO:0007613 31 18 0,000 0,04561856 0,06838521 ! regulation of systemic arterial blood pressure by hormone GO:0001990 28 18 0,000 0,04561856 0,06834263 GO:0050886|endocrine process, ! negative regulation of ion transport GO:0043271 24 18 0,000 0,04561856 0,0683001 ! patterning of blood vessels GO:0001569 39 18 0,000 0,04561856 0,06825763 ! cellular response to hydrogen peroxide GO:0070301 23 18 0,000 0,04561856 0,0682152 GO:0042744|hydrogen peroxide catabolic process, ! centrosome cycle GO:0007098 25 18 0,000 0,04561856 0,06817283 ! positive regulation of proteolysis GO:0045862 31 18 0,000 0,04561856 0,06813052 ! epidermis morphogenesis GO:0048730 40 18 0,000 0,04561856 0,06808825 ! glutamine metabolic process GO:0006541 29 18 0,000 0,04561856 0,06804604 ! cell-substrate junction assembly GO:0007044 54 18 0,000 0,04561856 0,06800388 ! peptidyl-serine phosphorylation GO:0018105 38 18 0,000 0,04561856 0,06796177 ! response to fungus GO:0009620 21 18 0,000 0,04561856 0,06791972 ! positive regulation of alpha-beta T cell differentiation GO:0046638 28 18 0,000 0,04561856 0,06787771 ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 26 18 0,000 0,04561856 0,06783576 ! regulation of steroid metabolic process GO:0019218 30 18 0,000 0,04561856 0,06779386 ! long-chain fatty acid transport GO:0015909 31 18 0,000 0,04561856 0,06775201 ! peptide biosynthetic process GO:0043043 24 18 0,000 0,04561856 0,06771022 ! vitamin transport GO:0051180 27 18 0,000 0,04561856 0,06766847 ! regulation of immunoglobulin production GO:0002637 43 18 0,000 0,04561856 0,06762678 ! porphyrin biosynthetic process GO:0006779 33 18 0,000 0,04561856 0,06758514 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 32 18 0,000 0,04561856 0,06754355 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 32 18 0,000 0,04561856 0,06750201 ! aromatic compound catabolic process GO:0019439 27 18 0,000 0,04561856 0,06746052 ! nerve development GO:0021675 28 18 0,000 0,04561856 0,06741908 ! positive regulation of synaptic transmission GO:0050806 28 18 0,000 0,04561856 0,06737769 ! protein secretion GO:0009306 39 19 0,000 0,04809179 0,07098703 ! positive regulation of translation GO:0045727 30 19 0,000 0,04809179 0,0709435 ! negative regulation of defense response GO:0031348 25 19 0,000 0,04809179 0,07090003 ! positive regulation of angiogenesis GO:0045766 44 19 0,000 0,04809179 0,07085662 ! positive regulation of hormone secretion GO:0046887 32 19 0,000 0,04809179 0,07081325 ! skin development GO:0043588 36 19 0,000 0,04809179 0,07076994 ! regulation of neuronal synaptic plasticity GO:0048168 41 19 0,000 0,04809179 0,07072668 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 28 19 0,000 0,04809179 0,07068348 ! forelimb morphogenesis GO:0035136 32 19 0,000 0,04809179 0,07064033 ! regulation of postsynaptic membrane potential GO:0060078 32 19 0,000 0,04809179 0,07059723 ! bile acid metabolic process GO:0008206 29 19 0,000 0,04809179 0,07055418 ! mitotic chromosome condensation GO:0007076 34 19 0,000 0,04809179 0,07051118 ! negative regulation of epithelial cell proliferation GO:0050680 46 19 0,000 0,04809179 0,07046824 ! cerebral cortex development GO:0021987 36 19 0,000 0,04809179 0,07042535 ! pigmentation during development GO:0048066 41 19 0,000 0,04809179 0,07038251 ! cellular response to unfolded protein GO:0034620 33 19 0,000 0,04809179 0,07033973 GO:0030968|endoplasmic reticulum unfolded protein response, ! heme metabolic process GO:0042168 36 19 0,000 0,04809179 0,070297 ! actin filament bundle formation GO:0051017 42 19 0,000 0,04809179 0,07025431 ! response to lipopolysaccharide GO:0032496 30 19 0,000 0,04809179 0,07021168 ! plasma membrane fusion GO:0045026 28 19 0,000 0,04809179 0,0701691 ! regulation of endothelial cell migration GO:0010594 44 19 0,000 0,04809179 0,07012658 ! peptide cross-linking GO:0018149 37 19 0,000 0,04809179 0,0700841 ! protein export from nucleus GO:0006611 36 19 0,000 0,04809179 0,07004168 ! heart process GO:0003015 30 19 0,000 0,04809179 0,06999931 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 37 19 0,000 0,04809179 0,06995699 GO:0006692|prostanoid metabolic process, ! regulation of phosphoinositide 3-kinase cascade GO:0014066 27 19 0,000 0,04809179 0,06991472 ! visual learning GO:0008542 36 19 0,000 0,04809179 0,0698725 ! cellular pigmentation GO:0033059 36 19 0,000 0,04809179 0,06983033 ! G1 phase GO:0051318 40 19 0,000 0,04809179 0,06978821 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 32 19 0,000 0,04809179 0,06974614 ! cell-cell junction organization GO:0045216 35 19 0,000 0,04809179 0,06970413 ! positive regulation of myeloid cell differentiation GO:0045639 59 19 0,000 0,04809179 0,06966216 ! positive regulation of transmission of nerve impulse GO:0051971 29 19 0,000 0,04809179 0,06962025 ! purine nucleotide catabolic process GO:0006195 29 19 0,000 0,04809179 0,06957838 ! proximal/distal pattern formation GO:0009954 32 19 0,000 0,04809179 0,06953657 ! estrogen receptor signaling pathway GO:0030520 38 19 0,000 0,04809179 0,06949481 ! somatic recombination of immunoglobulin gene segments GO:0016447 47 19 0,000 0,04809179 0,06945309 ! embryonic organ morphogenesis GO:0048562 26 19 0,000 0,04809179 0,06941143 ! cilium assembly GO:0042384 37 19 0,000 0,04809179 0,06936982 ! peptide hormone secretion GO:0030072 31 19 0,000 0,04809179 0,06932825 ! protein import into nucleus, docking GO:0000059 41 20 0,000 0,0505587 0,07284085 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 31 20 0,000 0,0505587 0,07279726 ! positive regulation of ossification GO:0045778 47 20 0,000 0,0505587 0,07275372 ! pteridine and derivative metabolic process GO:0042558 29 20 0,000 0,0505587 0,07271023 ! protein amino acid deacetylation GO:0006476 29 20 0,000 0,0505587 0,0726668 ! transcription from RNA polymerase III promoter GO:0006383 41 20 0,000 0,0505587 0,07262342 ! gamma-aminobutyric acid signaling pathway GO:0007214 26 20 0,000 0,0505587 0,07258008 ! response to alkaloid GO:0043279 38 20 0,000 0,0505587 0,0725368 ! retinoid metabolic process GO:0001523 32 20 0,000 0,0505587 0,07249358 GO:0016101|diterpenoid metabolic process, ! pancreas development GO:0031016 35 20 0,000 0,0505587 0,0724504 ! apoptotic mitochondrial changes GO:0008637 41 20 0,000 0,0505587 0,07240727 ! photoreceptor cell maintenance GO:0045494 34 20 0,000 0,0505587 0,0723642 ! response to carbohydrate stimulus GO:0009743 29 20 0,000 0,0505587 0,07232118 ! DNA duplex unwinding GO:0032508 31 20 0,000 0,0505587 0,07227821 GO:0032392|DNA geometric change, ! cellular response to starvation GO:0009267 33 20 0,000 0,0505587 0,07223529 ! actin polymerization or depolymerization GO:0008154 48 20 0,000 0,0505587 0,07219242 ! D-ribose metabolic process GO:0006014 29 20 0,000 0,0505587 0,0721496 ! body fluid secretion GO:0007589 31 20 0,000 0,0505587 0,07210683 ! fatty acid beta-oxidation GO:0006635 34 20 0,000 0,0505587 0,07206411 ! peptide secretion GO:0002790 35 20 0,000 0,0505587 0,07202145 ! stem cell differentiation GO:0048863 53 20 0,000 0,0505587 0,07197883 ! behavioral interaction between organisms GO:0051705 38 20 0,000 0,0505587 0,07193626 ! regulation of interleukin-2 production GO:0032663 35 20 0,000 0,0505587 0,07189375 ! sensory perception of pain GO:0019233 30 20 0,000 0,0505587 0,07185128 ! ribosomal small subunit biogenesis GO:0042274 24 20 0,000 0,0505587 0,07180887 ! diencephalon development GO:0021536 34 20 0,000 0,0505587 0,0717665 ! protein localization in mitochondrion GO:0070585 32 20 0,000 0,0505587 0,07172419 GO:0006626|protein targeting to mitochondrion, ! negative regulation of angiogenesis GO:0016525 45 20 0,000 0,0505587 0,07168192 ! detection of chemical stimulus GO:0009593 37 20 0,000 0,0505587 0,07163971 ! peptidyl-serine modification GO:0018209 43 20 0,000 0,0505587 0,07159754 ! positive regulation of neurological system process GO:0031646 32 20 0,000 0,0505587 0,07155542 ! negative regulation of myeloid cell differentiation GO:0045638 29 20 0,000 0,0505587 0,07151336 ! leukotriene biosynthetic process GO:0019370 37 20 0,000 0,0505587 0,07147134 GO:0043450|alkene biosynthetic process, ! regulation of leukocyte mediated cytotoxicity GO:0001910 40 20 0,000 0,0505587 0,07142937 ! camera-type eye morphogenesis GO:0048593 42 20 0,000 0,0505587 0,07138745 ! regulation of glucose import GO:0046324 29 20 0,000 0,0505587 0,07134558 GO:0010827|regulation of glucose transport, ! pyrimidine nucleotide biosynthetic process GO:0006221 28 20 0,000 0,0505587 0,07130376 ! actin filament-based movement GO:0030048 43 20 0,000 0,0505587 0,07126199 ! inner ear receptor cell differentiation GO:0060113 37 20 0,000 0,0505587 0,07122027 ! binding of sperm to zona pellucida GO:0007339 20 20 0,000 0,0505587 0,0711786 ! negative regulation of translation GO:0017148 29 20 0,000 0,0505587 0,07113697 ! negative regulation of coagulation GO:0050819 29 20 0,000 0,0505587 0,0710954 ! cellular monovalent inorganic cation homeostasis GO:0030004 36 20 0,000 0,0505587 0,07105387 ! regulation of cell killing GO:0031341 42 21 0,000 0,05301929 0,07446842 ! reciprocal meiotic recombination GO:0007131 39 21 0,000 0,05301929 0,07442497 ! phosphatidylinositol metabolic process GO:0046488 36 21 0,000 0,05301929 0,07438158 ! hormone secretion GO:0046879 38 21 0,000 0,05301929 0,07433823 ! glycerol metabolic process GO:0006071 34 21 0,000 0,05301929 0,07429494 ! intra-Golgi vesicle-mediated transport GO:0006891 40 21 0,000 0,05301929 0,07425169 ! hindlimb morphogenesis GO:0035137 43 21 0,000 0,05301929 0,0742085 ! regulation of neurotransmitter transport GO:0051588 42 21 0,000 0,05301929 0,07416535 ! axis specification GO:0009798 38 21 0,000 0,05301929 0,07412226 ! ovarian follicle development GO:0001541 35 21 0,000 0,05301929 0,07407921 ! inactivation of MAPK activity GO:0000188 39 21 0,000 0,05301929 0,07403622 ! smooth muscle contraction GO:0006939 46 21 0,000 0,05301929 0,07399327 ! cellular macromolecular complex disassembly GO:0034623 43 21 0,000 0,05301929 0,07395038 ! cell structure disassembly during apoptosis GO:0006921 30 21 0,000 0,05301929 0,07390753 ! neurotransmitter metabolic process GO:0042133 34 21 0,000 0,05301929 0,07386474 ! cell aging GO:0007569 44 21 0,000 0,05301929 0,07382199 ! regulation of alpha-beta T cell differentiation GO:0046637 37 21 0,000 0,05301929 0,0737793 ! positive regulation of alpha-beta T cell activation GO:0046635 33 21 0,000 0,05301929 0,07373665 ! regulation of myeloid leukocyte differentiation GO:0002761 39 21 0,000 0,05301929 0,07369405 ! cytolysis GO:0019835 24 21 0,000 0,05301929 0,0736515 ! vasodilation GO:0042311 39 21 0,000 0,05301929 0,073609 ! regulation of Rho GTPase activity GO:0032319 43 21 0,000 0,05301929 0,07356655 ! oogenesis GO:0048477 36 21 0,000 0,05301929 0,07352415 ! DNA modification GO:0006304 34 21 0,000 0,05301929 0,0734818 ! positive regulation of locomotion GO:0040017 39 21 0,000 0,05301929 0,0734395 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! collagen fibril organization GO:0030199 59 21 0,000 0,05301929 0,07339724 ! detection of biotic stimulus GO:0009595 29 21 0,000 0,05301929 0,07335503 ! positive regulation of inflammatory response GO:0050729 35 21 0,000 0,05301929 0,07331288 ! sphingolipid biosynthetic process GO:0030148 40 21 0,000 0,05301929 0,07327077 ! vitamin A metabolic process GO:0006776 33 21 0,000 0,05301929 0,07322871 ! positive regulation of osteoblast differentiation GO:0045669 49 21 0,000 0,05301929 0,07318669 ! response to cytokine stimulus GO:0034097 63 21 0,000 0,05301929 0,07314473 ! terpenoid metabolic process GO:0006721 37 21 0,000 0,05301929 0,07310281 ! collagen catabolic process GO:0030574 28 21 0,000 0,05301929 0,07306094 ! sperm-egg recognition GO:0035036 21 21 0,000 0,05301929 0,07301912 ! gut development GO:0048565 39 21 0,000 0,05301929 0,07297735 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 27 22 0,000 0,05547358 0,07631186 ! sulfur amino acid metabolic process GO:0000096 41 22 0,000 0,05547358 0,07626825 ! cellular aldehyde metabolic process GO:0006081 34 22 0,000 0,05547358 0,0762247 ! positive regulation of bone remodeling GO:0046852 51 22 0,000 0,05547358 0,07618119 GO:0034105|positive regulation of tissue remodeling, ! microtubule-based transport GO:0010970 54 22 0,000 0,05547358 0,07613773 ! regulation of chemotaxis GO:0050920 40 22 0,000 0,05547358 0,07609432 ! regulation of receptor-mediated endocytosis GO:0048259 28 22 0,000 0,05547358 0,07605096 ! glutamate signaling pathway GO:0007215 41 22 0,000 0,05547358 0,07600765 ! regeneration GO:0031099 41 22 0,000 0,05547358 0,07596439 ! keratinization GO:0031424 28 22 0,000 0,05547358 0,07592118 ! mechanoreceptor differentiation GO:0042490 40 22 0,000 0,05547358 0,07587802 ! sensory perception of taste GO:0050909 28 22 0,000 0,05547358 0,07583491 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 59 22 0,000 0,05547358 0,07579185 ! deoxyribonucleotide metabolic process GO:0009262 32 22 0,000 0,05547358 0,07574883 ! vacuolar transport GO:0007034 36 22 0,000 0,05547358 0,07570587 ! lysosome organization GO:0007040 41 22 0,000 0,05547358 0,07566295 ! central nervous system neuron development GO:0021954 46 22 0,000 0,05547358 0,07562008 ! cellular response to reactive oxygen species GO:0034614 31 22 0,000 0,05547358 0,07557726 ! positive regulation of cytoskeleton organization GO:0051495 48 22 0,000 0,05547358 0,07553449 ! fucose metabolic process GO:0006004 39 22 0,000 0,05547358 0,07549177 ! vesicle docking during exocytosis GO:0006904 41 22 0,000 0,05547358 0,07544909 ! apoptotic nuclear changes GO:0030262 32 22 0,000 0,05547358 0,07540646 ! ureteric bud development GO:0001657 43 22 0,000 0,05547358 0,07536389 ! renal system process GO:0003014 41 22 0,000 0,05547358 0,07532136 ! positive regulation of adaptive immune response GO:0002821 39 22 0,000 0,05547358 0,07527887 ! response to glucocorticoid stimulus GO:0051384 38 22 0,000 0,05547358 0,07523644 ! regulation of cytokine secretion GO:0050707 37 22 0,000 0,05547358 0,07519405 ! sarcomere organization GO:0045214 30 22 0,000 0,05547358 0,07515171 ! activation of JUN kinase activity GO:0007257 42 22 0,000 0,05547358 0,07510942 ! aromatic amino acid family metabolic process GO:0009072 32 22 0,000 0,05547358 0,07506718 ! somatic diversification of immunoglobulins GO:0016445 50 22 0,000 0,05547358 0,07502498 ! regulation of mitotic metaphase/anaphase transition GO:0030071 42 22 0,000 0,05547358 0,07498283 ! regulation of microtubule polymerization or depolymerization GO:0031110 61 22 0,000 0,05547358 0,07494073 ! protein stabilization GO:0050821 39 22 0,000 0,05547358 0,07489868 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 33 23 0,000 0,0579216 0,07816005 ! regulation of anti-apoptosis GO:0045767 53 23 0,000 0,0579216 0,07811624 ! gluconeogenesis GO:0006094 33 23 0,000 0,0579216 0,07807248 ! membrane lipid biosynthetic process GO:0046467 42 23 0,000 0,0579216 0,07802876 ! nucleotide-excision repair, DNA damage removal GO:0000718 33 23 0,000 0,0579216 0,0779851 ! protein amino acid O-linked glycosylation GO:0006493 42 23 0,000 0,0579216 0,07794148 ! glucosamine metabolic process GO:0006041 30 23 0,000 0,0579216 0,07789791 GO:0006044|N-acetylglucosamine metabolic process, ! leukocyte adhesion GO:0007159 50 23 0,000 0,0579216 0,0778544 ! glycosaminoglycan biosynthetic process GO:0006024 42 23 0,000 0,0579216 0,07781093 ! visual behavior GO:0007632 42 23 0,000 0,0579216 0,07776751 ! regulation of cell-matrix adhesion GO:0001952 78 23 0,000 0,0579216 0,07772413 GO:0010810|regulation of cell-substrate adhesion, ! regulation of DNA recombination GO:0000018 48 23 0,000 0,0579216 0,07768081 ! response to ethanol GO:0045471 46 23 0,000 0,0579216 0,07763753 ! immune response-activating cell surface receptor signaling pathway GO:0002429 40 23 0,000 0,0579216 0,0775943 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! activation of pro-apoptotic gene products GO:0008633 47 23 0,000 0,0579216 0,07755112 ! peroxisome organization GO:0007031 37 23 0,000 0,0579216 0,07750799 ! polysaccharide catabolic process GO:0000272 27 23 0,000 0,0579216 0,07746491 ! purine ribonucleoside metabolic process GO:0046128 34 23 0,000 0,0579216 0,07742187 GO:0042278|purine nucleoside metabolic process, ! vesicle targeting GO:0006903 43 23 0,000 0,0579216 0,07737888 ! barbed-end actin filament capping GO:0051016 50 23 0,000 0,0579216 0,07733594 GO:0051693|actin filament capping, ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 47 23 0,000 0,0579216 0,07729305 ! regulation of viral reproduction GO:0050792 38 23 0,000 0,0579216 0,0772502 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 39 23 0,000 0,0579216 0,07720741 ! leukotriene metabolic process GO:0006691 42 23 0,000 0,0579216 0,07716466 ! glycosphingolipid metabolic process GO:0006687 41 23 0,000 0,0579216 0,07712195 ! regulation of interleukin-6 production GO:0032675 29 23 0,000 0,0579216 0,0770793 ! synaptic vesicle transport GO:0048489 46 23 0,000 0,0579216 0,07703669 ! fatty acid transport GO:0015908 44 23 0,000 0,0579216 0,07699413 ! platelet activation GO:0030168 37 23 0,000 0,0579216 0,07695161 ! regulation of bone mineralization GO:0030500 49 23 0,000 0,0579216 0,07690914 ! nerve-nerve synaptic transmission GO:0007270 49 23 0,000 0,0579216 0,07686672 ! hormone transport GO:0009914 40 23 0,000 0,0579216 0,07682435 ! cell-cell recognition GO:0009988 25 23 0,000 0,0579216 0,07678202 ! negative regulation of cytokine production GO:0001818 40 23 0,000 0,0579216 0,07673974 ! pyrimidine nucleoside metabolic process GO:0006213 29 23 0,000 0,0579216 0,07669751 ! negative regulation of catabolic process GO:0009895 50 23 0,000 0,0579216 0,07665532 ! acetyl-CoA catabolic process GO:0046356 36 23 0,000 0,0579216 0,07661318 GO:0006099|tricarboxylic acid cycle, ! response to molecule of bacterial origin GO:0002237 34 23 0,000 0,0579216 0,07657108 ! protein import into nucleus, translocation GO:0000060 46 24 0,000 0,06036335 0,0797552 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 54 24 0,000 0,06036335 0,07971143 GO:0016444|somatic cell DNA recombination, ! DNA catabolic process, endonucleolytic GO:0000737 35 24 0,000 0,06036335 0,07966771 ! regulation of transmembrane transport GO:0034762 38 24 0,000 0,06036335 0,07962403 ! post-Golgi vesicle-mediated transport GO:0006892 58 24 0,000 0,06036335 0,0795804 ! vesicle docking GO:0048278 47 24 0,000 0,06036335 0,07953682 ! spinal cord development GO:0021510 47 24 0,000 0,06036335 0,07949328 ! vacuole organization GO:0007033 43 24 0,000 0,06036335 0,0794498 ! multicellular organismal response to stress GO:0033555 49 24 0,000 0,06036335 0,07940636 ! digestive system process GO:0022600 39 24 0,000 0,06036335 0,07936297 ! central nervous system neuron differentiation GO:0021953 50 24 0,000 0,06036335 0,07931962 ! response to corticosteroid stimulus GO:0031960 41 24 0,000 0,06036335 0,07927632 ! regulation of behavior GO:0050795 43 24 0,000 0,06036335 0,07923308 ! regulation of alpha-beta T cell activation GO:0046634 42 24 0,000 0,06036335 0,07918987 ! lymphocyte proliferation GO:0046651 48 24 0,000 0,06036335 0,07914672 ! positive regulation of leukocyte mediated immunity GO:0002705 43 24 0,000 0,06036335 0,07910361 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of tumor necrosis factor production GO:0032680 34 24 0,000 0,06036335 0,07906055 ! membrane depolarization GO:0051899 39 24 0,000 0,06036335 0,07901753 ! pentose metabolic process GO:0019321 35 24 0,000 0,06036335 0,07897457 ! leukocyte homeostasis GO:0001776 44 24 0,000 0,06036335 0,07893165 ! cellular alkene metabolic process GO:0043449 43 24 0,000 0,06036335 0,07888877 ! glutamine family amino acid catabolic process GO:0009065 39 24 0,000 0,06036335 0,07884594 ! aspartate family amino acid metabolic process GO:0009066 42 24 0,000 0,06036335 0,07880316 ! porphyrin metabolic process GO:0006778 46 24 0,000 0,06036335 0,07876043 GO:0033013|tetrapyrrole metabolic process, ! alditol metabolic process GO:0019400 38 24 0,000 0,06036335 0,07871774 ! regulation of multi-organism process GO:0043900 36 24 0,000 0,06036335 0,0786751 ! regulation of amine transport GO:0051952 40 24 0,000 0,06036335 0,0786325 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 32 25 0,000 0,06279886 0,08176085 ! aminoglycan biosynthetic process GO:0006023 44 25 0,000 0,06279886 0,08171663 ! dicarboxylic acid metabolic process GO:0043648 42 25 0,000 0,06279886 0,08167246 ! vasculogenesis GO:0001570 46 25 0,000 0,06279886 0,08162834 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 50 25 0,000 0,06279886 0,08158426 ! sperm motility GO:0030317 31 25 0,000 0,06279886 0,08154023 ! regulation of smooth muscle contraction GO:0006940 43 25 0,000 0,06279886 0,08149625 ! negative regulation of DNA replication GO:0008156 42 25 0,000 0,06279886 0,08145232 ! receptor metabolic process GO:0043112 46 25 0,000 0,06279886 0,08140843 ! chromosome condensation GO:0030261 45 25 0,000 0,06279886 0,08136459 ! response to starvation GO:0042594 42 25 0,000 0,06279886 0,0813208 ! osteoblast differentiation GO:0001649 60 25 0,000 0,06279886 0,08127706 ! response to endoplasmic reticulum stress GO:0034976 43 25 0,000 0,06279886 0,08123336 ! neural crest cell development GO:0014032 54 25 0,000 0,06279886 0,08118971 GO:0014033|neural crest cell differentiation, ! coenzyme catabolic process GO:0009109 39 25 0,000 0,06279886 0,08114611 ! regulation of insulin secretion GO:0050796 37 25 0,000 0,06279886 0,08110255 ! hydrogen peroxide metabolic process GO:0042743 33 25 0,000 0,06279886 0,08105904 ! regulation of biomineral formation GO:0070167 51 25 0,000 0,06279886 0,08101558 ! fibroblast growth factor receptor signaling pathway GO:0008543 44 25 0,000 0,06279886 0,08097216 ! ribonucleoside monophosphate metabolic process GO:0009161 42 25 0,000 0,06279886 0,08092879 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! immunoglobulin production GO:0002377 55 25 0,000 0,06279886 0,08088547 GO:0002440|production of molecular mediator of immune response, ! proteoglycan biosynthetic process GO:0030166 50 25 0,000 0,06279886 0,08084219 ! positive regulation of protein secretion GO:0050714 36 25 0,000 0,06279886 0,08079896 ! regulation of blood coagulation GO:0030193 40 25 0,000 0,06279886 0,08075577 ! cellular response to nutrient levels GO:0031669 41 25 0,000 0,06279886 0,08071264 ! neuromuscular process controlling balance GO:0050885 60 25 0,000 0,06279886 0,08066954 ! telomere organization GO:0032200 43 25 0,000 0,06279886 0,0806265 GO:0000723|telomere maintenance, ! neural tube closure GO:0001843 49 25 0,000 0,06279886 0,08058349 GO:0060606|tube closure, ! liver development GO:0001889 53 25 0,000 0,06279886 0,08054054 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 30 26 0,000 0,06522813 0,08361155 ! embryonic pattern specification GO:0009880 44 26 0,000 0,06522813 0,08356703 ! negative regulation of actin filament depolymerization GO:0030835 55 26 0,000 0,06522813 0,08352256 ! negative regulation of actin filament polymerization GO:0030837 53 26 0,000 0,06522813 0,08347813 ! regulation of interferon-gamma production GO:0032649 39 26 0,000 0,06522813 0,08343375 ! pyruvate metabolic process GO:0006090 38 26 0,000 0,06522813 0,08338942 ! acetyl-CoA metabolic process GO:0006084 39 26 0,000 0,06522813 0,08334513 ! cellular polysaccharide biosynthetic process GO:0033692 37 26 0,000 0,06522813 0,08330089 ! molting cycle process GO:0022404 50 26 0,000 0,06522813 0,0832567 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! tube lumen formation GO:0035148 50 26 0,000 0,06522813 0,08321256 ! macromolecular complex disassembly GO:0032984 53 26 0,000 0,06522813 0,08316846 ! odontogenesis of dentine-containing tooth GO:0042475 48 26 0,000 0,06522813 0,08312441 ! microtubule organizing center organization GO:0031023 39 26 0,000 0,06522813 0,0830804 GO:0051297|centrosome organization, ! regulation of endothelial cell proliferation GO:0001936 57 26 0,000 0,06522813 0,08303645 ! cellular response to oxidative stress GO:0034599 39 26 0,000 0,06522813 0,08299254 ! response to estradiol stimulus GO:0032355 40 26 0,000 0,06522813 0,08294867 ! positive regulation of MAPKKK cascade GO:0043410 47 26 0,000 0,06522813 0,08290485 ! regulation of response to biotic stimulus GO:0002831 44 26 0,000 0,06522813 0,08286108 ! positive regulation of nuclear division GO:0051785 40 26 0,000 0,06522813 0,08281735 GO:0045840|positive regulation of mitosis, ! group transfer coenzyme metabolic process GO:0006752 47 26 0,000 0,06522813 0,08277367 ! regulation of osteoblast differentiation GO:0045667 65 26 0,000 0,06522813 0,08273004 ! somatic diversification of immune receptors GO:0002200 56 26 0,000 0,06522813 0,08268645 ! blastocyst development GO:0001824 49 26 0,000 0,06522813 0,08264291 ! leukocyte proliferation GO:0070661 52 26 0,000 0,06522813 0,08259941 GO:0032943|mononuclear cell proliferation, ! water-soluble vitamin biosynthetic process GO:0042364 35 26 0,000 0,06522813 0,08255596 ! positive regulation of JUN kinase activity GO:0043507 51 26 0,000 0,06522813 0,08251256 ! neuron fate commitment GO:0048663 48 27 0,000 0,06765119 0,08553272 ! positive regulation of smooth muscle cell proliferation GO:0048661 43 27 0,000 0,06765119 0,08548779 ! iron ion transport GO:0006826 59 27 0,000 0,06765119 0,08544292 ! spliceosomal snRNP biogenesis GO:0000387 36 27 0,000 0,06765119 0,08539809 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 55 27 0,000 0,06765119 0,08535331 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! superoxide metabolic process GO:0006801 38 27 0,000 0,06765119 0,08530857 ! fat cell differentiation GO:0045444 50 27 0,000 0,06765119 0,08526389 ! positive regulation of innate immune response GO:0045089 43 27 0,000 0,06765119 0,08521925 ! mitochondrial membrane organization GO:0007006 57 27 0,000 0,06765119 0,08517465 ! multicellular organismal catabolic process GO:0044243 36 27 0,000 0,06765119 0,0851301 ! autophagy GO:0006914 41 27 0,000 0,06765119 0,0850856 ! male gonad development GO:0008584 44 27 0,000 0,06765119 0,08504115 ! response to toxin GO:0009636 47 27 0,000 0,06765119 0,08499674 ! primary neural tube formation GO:0014020 51 27 0,000 0,06765119 0,08495238 ! base-excision repair GO:0006284 41 27 0,000 0,06765119 0,08490806 ! glycolipid metabolic process GO:0006664 47 27 0,000 0,06765119 0,0848638 ! regulation of chromosome organization GO:0033044 42 27 0,000 0,06765119 0,08481957 ! glutathione metabolic process GO:0006749 39 27 0,000 0,06765119 0,0847754 ! fat-soluble vitamin metabolic process GO:0006775 40 27 0,000 0,06765119 0,08473126 ! negative regulation of protein polymerization GO:0032272 55 27 0,000 0,06765119 0,08468718 ! regulation of actin filament depolymerization GO:0030834 58 28 0,000 0,07006804 0,08766704 ! circadian rhythm GO:0007623 50 28 0,000 0,07006804 0,08762147 ! dendrite development GO:0016358 59 28 0,000 0,07006804 0,08757596 ! negative regulation of protein modification process GO:0031400 60 28 0,000 0,07006804 0,08753049 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 45 28 0,000 0,07006804 0,08748506 ! ER-nuclear signaling pathway GO:0006984 48 28 0,000 0,07006804 0,08743969 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 53 28 0,000 0,07006804 0,08739436 ! vitamin biosynthetic process GO:0009110 39 28 0,000 0,07006804 0,08734908 ! regulation of systemic arterial blood pressure GO:0003073 54 28 0,000 0,07006804 0,08730384 ! positive regulation of T cell differentiation GO:0045582 42 28 0,000 0,07006804 0,08725865 ! synaptogenesis GO:0007416 42 28 0,000 0,07006804 0,08721351 ! lipid oxidation GO:0034440 43 28 0,000 0,07006804 0,08716842 GO:0019395|fatty acid oxidation, ! ethanolamine and derivative metabolic process GO:0042439 46 28 0,000 0,07006804 0,08712337 ! regulation of JUN kinase activity GO:0043506 58 28 0,000 0,07006804 0,08707837 ! translational initiation GO:0006413 65 29 0,000 0,07247872 0,09002777 ! icosanoid biosynthetic process GO:0046456 54 29 0,000 0,07247872 0,08998132 ! regulation of pH GO:0006885 43 29 0,000 0,07247872 0,08993491 ! cellular iron ion homeostasis GO:0006879 51 29 0,000 0,07247872 0,08988855 ! amino sugar metabolic process GO:0006040 38 29 0,000 0,07247872 0,08984224 ! catechol metabolic process GO:0009712 54 29 0,000 0,07247872 0,08979598 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! complement activation, classical pathway GO:0006958 48 29 0,000 0,07247872 0,08974976 ! respiratory gaseous exchange GO:0007585 57 29 0,000 0,07247872 0,0897036 ! regulation of peptide secretion GO:0002791 47 29 0,000 0,07247872 0,08965748 ! immune response-activating signal transduction GO:0002757 47 29 0,000 0,07247872 0,0896114 GO:0002764|immune response-regulating signal transduction, ! regulation of production of molecular mediator of immune response GO:0002700 61 29 0,000 0,07247872 0,08956538 ! response to organic cyclic substance GO:0014070 55 29 0,000 0,07247872 0,0895194 ! cell fate determination GO:0001709 60 29 0,000 0,07247872 0,08947347 ! regulation of microtubule cytoskeleton organization GO:0070507 70 29 0,000 0,07247872 0,08942759 ! negative regulation of neuron apoptosis GO:0043524 56 29 0,000 0,07247872 0,08938175 ! regulation of coagulation GO:0050818 46 29 0,000 0,07247872 0,08933596 ! phenol metabolic process GO:0018958 55 30 0,000 0,07488322 0,09225244 ! zinc ion transport GO:0006829 45 30 0,000 0,07488322 0,09220523 ! membrane docking GO:0022406 61 30 0,000 0,07488322 0,09215807 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 47 30 0,000 0,07488322 0,09211095 ! cell junction assembly GO:0034329 78 30 0,000 0,07488322 0,09206389 ! regulation of innate immune response GO:0045088 51 30 0,000 0,07488322 0,09201687 ! acute-phase response GO:0006953 49 30 0,000 0,07488322 0,09196989 ! myofibril assembly GO:0030239 47 30 0,000 0,07488322 0,09192297 GO:0055002|striated muscle cell development, ! negative regulation of protein kinase cascade GO:0010741 68 30 0,000 0,07488322 0,0918761 ! determination of left/right symmetry GO:0007368 47 30 0,000 0,07488322 0,09182927 ! positive regulation of multicellular organism growth GO:0040018 51 30 0,000 0,07488322 0,09178249 ! phospholipid transport GO:0015914 51 30 0,000 0,07488322 0,09173576 ! nicotinamide metabolic process GO:0006769 52 30 0,000 0,07488322 0,09168907 GO:0046496|nicotinamide nucleotide metabolic process, ! cofactor catabolic process GO:0051187 51 30 0,000 0,07488322 0,09164243 ! neurotransmitter secretion GO:0007269 48 30 0,000 0,07488322 0,09159584 ! eye morphogenesis GO:0048592 60 30 0,000 0,07488322 0,0915493 ! alkaloid metabolic process GO:0009820 53 31 0,000 0,07728157 0,09443344 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 46 31 0,000 0,07728157 0,09438551 ! mRNA export from nucleus GO:0006406 48 31 0,000 0,07728157 0,09433762 ! determination of bilateral symmetry GO:0009855 49 31 0,000 0,07728157 0,09428978 GO:0009799|determination of symmetry, ! collagen metabolic process GO:0032963 45 31 0,000 0,07728157 0,09424199 ! inner ear morphogenesis GO:0042472 47 31 0,000 0,07728157 0,09419425 ! cholesterol homeostasis GO:0042632 53 31 0,000 0,07728157 0,09414656 GO:0055092|sterol homeostasis, ! GPI anchor biosynthetic process GO:0006506 53 31 0,000 0,07728157 0,09409891 ! cellular carbohydrate biosynthetic process GO:0034637 42 31 0,000 0,07728157 0,09405131 ! ovulation cycle process GO:0022602 49 31 0,000 0,07728157 0,09400377 ! positive regulation of T cell proliferation GO:0042102 52 31 0,000 0,07728157 0,09395627 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 51 31 0,000 0,07728157 0,09390881 ! peptide transport GO:0015833 55 31 0,000 0,07728157 0,09386141 ! triglyceride metabolic process GO:0006641 43 31 0,000 0,07728157 0,09381405 ! iron ion homeostasis GO:0055072 54 31 0,000 0,07728157 0,09376674 ! erythrocyte differentiation GO:0030218 55 31 0,000 0,07728157 0,09371948 ! mesoderm formation GO:0001707 69 31 0,000 0,07728157 0,09367227 ! natural killer cell activation GO:0030101 45 31 0,000 0,07728157 0,0936251 ! serine family amino acid metabolic process GO:0009069 49 31 0,000 0,07728157 0,09357798 ! fatty acid catabolic process GO:0009062 48 31 0,000 0,07728157 0,09353091 ! myeloid leukocyte activation GO:0002274 49 31 0,000 0,07728157 0,09348389 ! negative regulation of transcription regulator activity GO:0090048 58 31 0,000 0,07728157 0,09343691 GO:0043433|negative regulation of transcription factor activity, ! positive regulation of immune effector process GO:0002699 67 31 0,000 0,07728157 0,09338998 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 47 32 0,000 0,07967378 0,09623248 ! response to hydrogen peroxide GO:0042542 50 32 0,000 0,07967378 0,0961842 ! proteoglycan metabolic process GO:0006029 63 32 0,000 0,07967378 0,09613596 ! negative regulation of response to external stimulus GO:0032102 47 32 0,000 0,07967378 0,09608777 ! cholesterol transport GO:0030301 56 32 0,000 0,07967378 0,09603963 ! GPI anchor metabolic process GO:0006505 56 32 0,000 0,07967378 0,09599154 ! spliceosome assembly GO:0000245 67 32 0,000 0,07967378 0,0959435 ! spindle organization GO:0007051 46 32 0,000 0,07967378 0,0958955 ! pigment biosynthetic process GO:0046148 66 32 0,000 0,07967378 0,09584755 ! metanephros development GO:0001656 74 32 0,000 0,07967378 0,09579965 ! unsaturated fatty acid biosynthetic process GO:0006636 59 32 0,000 0,07967378 0,0957518 ! response to ionizing radiation GO:0010212 65 32 0,000 0,07967378 0,095704 ! response to mechanical stimulus GO:0009612 57 32 0,000 0,07967378 0,09565624 ! regulation of axonogenesis GO:0050770 75 32 0,000 0,07967378 0,09560853 ! muscle cell development GO:0055001 49 32 0,000 0,07967378 0,09556087 ! nuclear-transcribed mRNA catabolic process GO:0000956 51 32 0,000 0,07967378 0,09551326 ! regulation of ARF GTPase activity GO:0032312 65 32 0,000 0,07967378 0,09546569 ! hexose biosynthetic process GO:0019319 48 32 0,000 0,07967378 0,09541817 ! negative regulation of MAP kinase activity GO:0043407 69 32 0,000 0,07967378 0,0953707 ! ovulation cycle GO:0042698 51 32 0,000 0,07967378 0,09532328 ! BMP signaling pathway GO:0030509 64 32 0,000 0,07967378 0,0952759 ! hindbrain development GO:0030902 61 32 0,000 0,07967378 0,09522857 ! positive regulation of lymphocyte differentiation GO:0045621 48 32 0,000 0,07967378 0,09518128 ! regulation of calcium ion transport GO:0051924 53 32 0,000 0,07967378 0,09513405 ! gene silencing GO:0016458 65 32 0,000 0,07967378 0,09508686 ! DNA damage checkpoint GO:0000077 71 33 0,000 0,08205986 0,09788599 ! post-embryonic development GO:0009791 69 33 0,000 0,08205986 0,09783748 ! positive regulation of gene-specific transcription GO:0043193 65 33 0,000 0,08205986 0,09778902 ! protein targeting to membrane GO:0006612 68 33 0,000 0,08205986 0,09774061 ! positive regulation of neurogenesis GO:0050769 67 33 0,000 0,08205986 0,09769225 ! ceramide metabolic process GO:0006672 64 33 0,000 0,08205986 0,09764393 ! formation of primary germ layer GO:0001704 72 33 0,000 0,08205986 0,09759567 ! cell fate specification GO:0001708 52 33 0,000 0,08205986 0,09754745 ! sterol transport GO:0015918 57 33 0,000 0,08205986 0,09749928 ! leukocyte chemotaxis GO:0030595 50 33 0,000 0,08205986 0,09745115 GO:0060326|cell chemotaxis, ! pyridine nucleotide metabolic process GO:0019362 55 33 0,000 0,08205986 0,09740308 ! adult locomotory behavior GO:0008344 59 33 0,000 0,08205986 0,09735505 ! establishment of vesicle localization GO:0051650 61 33 0,000 0,08205986 0,09730706 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 48 34 0,000 0,08443984 0,10007993 ! glial cell differentiation GO:0010001 63 34 0,000 0,08443984 0,10003066 ! xenobiotic metabolic process GO:0006805 51 34 0,000 0,08443984 0,09998143 ! positive regulation of endocytosis GO:0045807 50 34 0,000 0,08443984 0,09993225 ! antigen processing and presentation of peptide antigen GO:0048002 62 34 0,000 0,08443984 0,09988312 ! regulation of striated muscle tissue development GO:0016202 69 34 0,000 0,08443984 0,09983404 ! multicellular organismal macromolecule metabolic process GO:0044259 50 34 0,000 0,08443984 0,099785 ! mesoderm morphogenesis GO:0048332 76 34 0,000 0,08443984 0,09973602 ! mismatch repair GO:0006298 46 34 0,000 0,08443984 0,09968708 ! spermatid development GO:0007286 63 34 0,000 0,08443984 0,09963819 ! biogenic amine biosynthetic process GO:0042401 62 34 0,000 0,08443984 0,09958935 ! pyrimidine nucleotide metabolic process GO:0006220 52 34 0,000 0,08443984 0,09954055 ! placenta development GO:0001890 53 34 0,000 0,08443984 0,09949181 ! regulation of muscle development GO:0048634 70 35 0,000 0,08681373 0,10223879 ! regulation of smooth muscle cell proliferation GO:0048660 59 35 0,000 0,08681373 0,10218877 ! negative regulation of secretion GO:0051048 63 35 0,000 0,08681373 0,1021388 ! negative regulation of DNA metabolic process GO:0051053 61 35 0,000 0,08681373 0,10208888 ! regulation of synaptic plasticity GO:0048167 64 35 0,000 0,08681373 0,102039 ! negative regulation of cell adhesion GO:0007162 81 35 0,000 0,08681373 0,10198918 ! odontogenesis GO:0042476 66 35 0,000 0,08681373 0,10193941 ! embryonic skeletal system morphogenesis GO:0048704 59 35 0,000 0,08681373 0,10188968 ! female gonad development GO:0008585 58 35 0,000 0,08681373 0,10184 ! neutral lipid metabolic process GO:0006638 50 35 0,000 0,08681373 0,10179037 GO:0006639|acylglycerol metabolic process, ! negative regulation of hydrolase activity GO:0051346 62 35 0,000 0,08681373 0,10174079 ! cytokine production GO:0001816 59 35 0,000 0,08681373 0,10169126 ! regulation of microtubule-based process GO:0032886 78 35 0,000 0,08681373 0,10164177 ! neural tube formation GO:0001841 67 35 0,000 0,08681373 0,10159234 ! vesicle localization GO:0051648 64 35 0,000 0,08681373 0,10154295 ! mitotic sister chromatid segregation GO:0000070 57 36 0,000 0,08918155 0,10426181 ! negative regulation of adenylate cyclase activity GO:0007194 58 36 0,000 0,08918155 0,10421117 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! positive regulation of JAK-STAT cascade GO:0046427 50 36 0,000 0,08918155 0,10416058 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 49 36 0,000 0,08918155 0,10411004 ! cell junction organization GO:0034330 86 36 0,000 0,08918155 0,10405955 ! sphingoid metabolic process GO:0046519 70 36 0,000 0,08918155 0,10400911 ! maintenance of protein location in cell GO:0032507 86 36 0,000 0,08918155 0,10395872 ! positive regulation of cell development GO:0010720 80 36 0,000 0,08918155 0,10390838 ! DNA integrity checkpoint GO:0031570 75 36 0,000 0,08918155 0,10385808 ! regulation of proteolysis GO:0030162 72 36 0,000 0,08918155 0,10380784 ! aerobic respiration GO:0009060 55 36 0,000 0,08918155 0,10375764 ! embryonic organ development GO:0048568 57 36 0,000 0,08918155 0,10370749 ! monosaccharide biosynthetic process GO:0046364 52 36 0,000 0,08918155 0,10365739 ! RNA export from nucleus GO:0006405 56 37 0,000 0,0915433 0,10635112 ! cellular component assembly involved in morphogenesis GO:0010927 59 37 0,000 0,0915433 0,10629979 ! meiosis I GO:0007127 65 37 0,000 0,0915433 0,10624852 ! sister chromatid segregation GO:0000819 58 37 0,000 0,0915433 0,10619729 ! actomyosin structure organization GO:0031032 62 37 0,000 0,0915433 0,10614611 ! organic anion transport GO:0015711 68 37 0,000 0,0915433 0,10609498 ! tissue remodeling GO:0048771 76 37 0,000 0,0915433 0,1060439 ! monovalent inorganic cation homeostasis GO:0055067 58 37 0,000 0,0915433 0,10599286 ! negative regulation of DNA binding GO:0043392 68 37 0,000 0,0915433 0,10594188 ! glycerol ether metabolic process GO:0006662 53 37 0,000 0,0915433 0,10589095 ! energy coupled proton transport, down electrochemical gradient GO:0015985 62 37 0,000 0,0915433 0,10584006 GO:0015986|ATP synthesis coupled proton transport, ! regulation of protein stability GO:0031647 73 37 0,000 0,0915433 0,10578923 ! glycogen metabolic process GO:0005977 61 37 0,000 0,0915433 0,10573844 ! pigment metabolic process GO:0042440 80 37 0,000 0,0915433 0,1056877 ! spermatid differentiation GO:0048515 66 37 0,000 0,0915433 0,10563701 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 58 38 0,000 0,093899 0,10830345 GO:0006956|complement activation, ! phosphoinositide biosynthetic process GO:0046489 67 38 0,000 0,093899 0,10825156 ! regulation of neuron projection development GO:0010975 91 38 0,000 0,093899 0,10819971 ! regulation of metal ion transport GO:0010959 63 38 0,000 0,093899 0,10814792 ! mitotic cell cycle checkpoint GO:0007093 76 38 0,000 0,093899 0,10809617 ! development of primary female sexual characteristics GO:0046545 67 38 0,000 0,093899 0,10804448 GO:0046660|female sex differentiation, ! nucleus organization GO:0006997 67 38 0,000 0,093899 0,10799283 ! lipid homeostasis GO:0055088 67 38 0,000 0,093899 0,10794123 ! nucleotide catabolic process GO:0009166 61 38 0,000 0,093899 0,10788968 ! erythrocyte homeostasis GO:0034101 64 38 0,000 0,093899 0,10783819 ! isoprenoid metabolic process GO:0006720 66 38 0,000 0,093899 0,10778674 ! embryonic epithelial tube formation GO:0001838 72 38 0,000 0,093899 0,10773534 ! regulation of cell morphogenesis involved in differentiation GO:0010769 90 38 0,000 0,093899 0,10768398 ! glucan metabolic process GO:0044042 62 38 0,000 0,093899 0,10763268 GO:0006073|cellular glucan metabolic process, ! mRNA catabolic process GO:0006402 71 39 0,000 0,09624868 0,11027349 ! ear morphogenesis GO:0042471 60 39 0,000 0,09624868 0,110221 ! organic ether metabolic process GO:0018904 55 39 0,000 0,09624868 0,11016856 ! development of primary male sexual characteristics GO:0046546 66 39 0,000 0,09624868 0,11011618 ! ion transmembrane transport GO:0034220 66 39 0,000 0,09624868 0,11006384 ! regulation of lymphocyte mediated immunity GO:0002706 74 39 0,000 0,09624868 0,11001155 ! Rho protein signal transduction GO:0007266 74 39 0,000 0,09624868 0,10995932 ! RNA modification GO:0009451 57 39 0,000 0,09624868 0,10990713 ! response to xenobiotic stimulus GO:0009410 57 39 0,000 0,09624868 0,10985499 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 62 40 0,000 0,09859234 0,11247661 ! regulation of hormone secretion GO:0046883 62 40 0,000 0,09859234 0,1124233 ! ER to Golgi vesicle-mediated transport GO:0006888 85 40 0,000 0,09859234 0,11237004 ! feeding behavior GO:0007631 59 40 0,000 0,09859234 0,11231684 ! negative regulation of binding GO:0051100 72 40 0,000 0,09859234 0,11226368 ! multicellular organismal metabolic process GO:0044236 57 40 0,000 0,09859234 0,11221058 ! ribonucleoside metabolic process GO:0009119 55 40 0,000 0,09859234 0,11215752 ! maintenance of protein location GO:0045185 91 40 0,000 0,09859234 0,11210452 ! cytokinesis GO:0000910 72 40 0,000 0,09859234 0,11205157 ! protein amino acid N-linked glycosylation GO:0006487 65 41 0,000 0,10093 0,11465419 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 70 41 0,000 0,10093 0,11460008 ! cellular amide metabolic process GO:0043603 67 41 0,000 0,10093 0,11454603 ! calcium-dependent cell-cell adhesion GO:0016339 52 41 0,000 0,10093 0,11449202 ! gliogenesis GO:0042063 88 41 0,000 0,10093 0,11443807 ! hormone-mediated signaling GO:0009755 74 41 0,000 0,10093 0,11438416 ! T cell differentiation GO:0030217 81 41 0,000 0,10093 0,11433031 ! keratinocyte differentiation GO:0030216 62 41 0,000 0,10093 0,11427651 ! female gamete generation GO:0007292 61 41 0,000 0,10093 0,11422275 ! polyol metabolic process GO:0019751 66 41 0,000 0,10093 0,11416905 ! dorsal/ventral pattern formation GO:0009953 68 41 0,000 0,10093 0,1141154 ! response to reactive oxygen species GO:0000302 67 42 0,000 0,10326167 0,11669685 ! negative regulation of protein complex disassembly GO:0043242 101 42 0,000 0,10326167 0,11664206 ! regulation of tube size GO:0035150 71 42 0,000 0,10326167 0,11658732 GO:0050880|regulation of blood vessel size, ! monocarboxylic acid transport GO:0015718 85 42 0,000 0,10326167 0,11653264 ! cytoskeleton-dependent intracellular transport GO:0030705 97 42 0,000 0,10326167 0,116478 ! alcohol biosynthetic process GO:0046165 59 42 0,000 0,10326167 0,11642342 ! regulation of leukocyte mediated immunity GO:0002703 79 42 0,000 0,10326167 0,11636889 ! neuron migration GO:0001764 79 42 0,000 0,10326167 0,11631441 ! regulation of protein secretion GO:0050708 71 42 0,000 0,10326167 0,11625998 ! regulation of myeloid cell differentiation GO:0045637 98 42 0,000 0,10326167 0,11620561 ! epithelial cell differentiation GO:0030855 79 43 0,000 0,10558738 0,11876729 ! transforming growth factor beta receptor signaling pathway GO:0007179 76 43 0,000 0,10558738 0,11871179 ! receptor-mediated endocytosis GO:0006898 88 43 0,000 0,10558738 0,11865634 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 78 43 0,000 0,10558738 0,11860095 ! energy reserve metabolic process GO:0006112 74 43 0,000 0,10558738 0,11854561 ! glucose transport GO:0015758 65 43 0,000 0,10558738 0,11849031 ! positive regulation of response to external stimulus GO:0032103 77 43 0,000 0,10558738 0,11843507 ! neural tube development GO:0021915 77 43 0,000 0,10558738 0,11837988 ! striated muscle contraction GO:0006941 77 43 0,000 0,10558738 0,11832475 ! phagocytosis GO:0006909 90 43 0,000 0,10558738 0,11826966 ! heterocycle biosynthetic process GO:0018130 69 43 0,000 0,10558738 0,11821463 ! activation of adenylate cyclase activity GO:0007190 91 44 0,000 0,10790713 0,12075561 ! hexose transport GO:0008645 67 44 0,000 0,10790713 0,12069947 GO:0015749|monosaccharide transport, ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 98 44 0,000 0,10790713 0,12064338 ! male sex differentiation GO:0046661 76 44 0,000 0,10790713 0,12058734 ! B cell differentiation GO:0030183 107 44 0,000 0,10790713 0,12053136 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 77 44 0,000 0,10790713 0,12047543 ! JAK-STAT cascade GO:0007259 71 44 0,000 0,10790713 0,12041955 ! developmental growth GO:0048589 82 44 0,000 0,10790713 0,12036372 ! maintenance of location in cell GO:0051651 97 44 0,000 0,10790713 0,12030795 ! regulation of actin filament polymerization GO:0030833 87 45 0,000 0,11022094 0,12283075 ! glycolysis GO:0006096 65 45 0,000 0,11022094 0,12277388 ! regulation of JAK-STAT cascade GO:0046425 70 45 0,000 0,11022094 0,12271707 ! leukocyte migration GO:0050900 68 45 0,000 0,11022094 0,12266031 ! branching morphogenesis of a tube GO:0048754 97 45 0,000 0,11022094 0,1226036 ! polysaccharide biosynthetic process GO:0000271 70 45 0,000 0,11022094 0,12254694 ! positive regulation of cytokine biosynthetic process GO:0042108 65 45 0,000 0,11022094 0,12249034 ! ATP synthesis coupled electron transport GO:0042773 64 45 0,000 0,11022094 0,12243379 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! icosanoid metabolic process GO:0006690 80 45 0,000 0,11022094 0,12237729 ! oxidoreduction coenzyme metabolic process GO:0006733 72 45 0,000 0,11022094 0,12232084 ! cell growth GO:0016049 84 45 0,000 0,11022094 0,12226445 ! positive regulation of adenylate cyclase activity GO:0045762 101 46 0,000 0,11252883 0,12476698 ! negative regulation of cell migration GO:0030336 115 46 0,000 0,11252883 0,12470951 ! epidermal cell differentiation GO:0009913 68 46 0,000 0,11252883 0,1246521 ! pigmentation GO:0043473 100 46 0,000 0,11252883 0,12459473 ! positive regulation of defense response GO:0031349 76 47 0,000 0,1148308 0,12708506 ! response to calcium ion GO:0051592 81 47 0,000 0,1148308 0,12702663 ! endosome transport GO:0016197 108 47 0,000 0,1148308 0,12696825 ! vascular process in circulatory system GO:0003018 80 47 0,000 0,1148308 0,12690993 ! positive regulation of cyclase activity GO:0031281 103 47 0,000 0,1148308 0,12685166 ! regulation of adaptive immune response GO:0002819 84 47 0,000 0,1148308 0,12679344 ! JNK cascade GO:0007254 91 47 0,000 0,1148308 0,12673528 ! regulation of JNK cascade GO:0046328 94 47 0,000 0,1148308 0,12667717 ! mitochondrial transport GO:0006839 82 48 0,000 0,11712689 0,12915091 ! Notch signaling pathway GO:0007219 96 48 0,000 0,11712689 0,12909175 ! cellular component disassembly GO:0022411 86 48 0,000 0,11712689 0,12903264 ! morphogenesis of embryonic epithelium GO:0016331 91 48 0,000 0,11712689 0,12897359 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 98 48 0,000 0,11712689 0,12891459 ! regulation of ARF protein signal transduction GO:0032012 102 48 0,000 0,11712689 0,12885564 ! activation of caspase activity GO:0006919 84 48 0,000 0,11712689 0,12879675 ! positive regulation of lyase activity GO:0051349 104 48 0,000 0,11712689 0,12873791 ! regulation of inflammatory response GO:0050727 75 48 0,000 0,11712689 0,12867913 ! protein amino acid lipidation GO:0006497 95 49 0,000 0,11941709 0,13113533 ! regulation of protein complex disassembly GO:0043244 113 49 0,000 0,11941709 0,13107551 ! stress-activated protein kinase signaling pathway GO:0031098 97 49 0,000 0,11941709 0,13101574 ! regulation of ion transport GO:0043269 77 49 0,000 0,11941709 0,13095602 ! induction of apoptosis by extracellular signals GO:0008624 89 49 0,000 0,11941709 0,13089636 ! peptide metabolic process GO:0006518 76 49 0,000 0,11941709 0,13083676 ! unsaturated fatty acid metabolic process GO:0033559 86 49 0,000 0,11941709 0,1307772 ! endocrine system development GO:0035270 104 49 0,000 0,11941709 0,1307177 ! DNA-dependent DNA replication GO:0006261 74 49 0,000 0,11941709 0,13065826 ! immunoglobulin mediated immune response GO:0016064 83 49 0,000 0,11941709 0,13059887 GO:0019724|B cell mediated immunity, ! ribonucleoprotein complex assembly GO:0022618 95 49 0,000 0,11941709 0,13053953 ! neuromuscular process GO:0050905 99 50 0,000 0,12170143 0,13297622 ! regulation of ossification GO:0030278 117 50 0,000 0,12170143 0,13291586 ! inner ear development GO:0048839 79 50 0,000 0,12170143 0,13285555 ! regulation of gene expression, epigenetic GO:0040029 105 50 0,000 0,12170143 0,1327953 ! positive regulation of cytokine production GO:0001819 86 50 0,000 0,12170143 0,1327351 ! response to estrogen stimulus GO:0043627 93 51 0,000 0,12397991 0,13515889 ! cellular amino acid biosynthetic process GO:0008652 75 51 0,000 0,12397991 0,13509768 ! embryonic skeletal system development GO:0048706 85 51 0,000 0,12397991 0,13503652 ! excretion GO:0007588 83 51 0,000 0,12397991 0,13497542 ! RNA elongation from RNA polymerase II promoter GO:0006368 72 51 0,000 0,12397991 0,13491437 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 70 51 0,000 0,12397991 0,13485338 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 76 51 0,000 0,12397991 0,13479244 ! vesicle organization GO:0016050 107 51 0,000 0,12397991 0,13473156 ! regulation of cell shape GO:0008360 125 51 0,000 0,12397991 0,13467073 ! epithelial tube morphogenesis GO:0060562 98 51 0,000 0,12397991 0,13460996 ! regulation of muscle contraction GO:0006937 81 52 0,000 0,12625257 0,13701564 ! membrane fusion GO:0006944 110 52 0,000 0,12625257 0,13695387 ! morphogenesis of a branching structure GO:0001763 111 52 0,000 0,12625257 0,13689215 ! cartilage development GO:0051216 90 52 0,000 0,12625257 0,13683048 ! respiratory electron transport chain GO:0022904 76 53 0,000 0,1285194 0,13922453 ! RNA catabolic process GO:0006401 93 53 0,000 0,1285194 0,13916187 ! lipoprotein biosynthetic process GO:0042158 101 53 0,000 0,1285194 0,13909927 ! regulation of actin polymerization or depolymerization GO:0008064 98 53 0,000 0,1285194 0,13903672 ! cell maturation GO:0048469 100 53 0,000 0,1285194 0,13897423 ! regulation of neuron apoptosis GO:0043523 100 53 0,000 0,1285194 0,1389118 ! regulation of protein polymerization GO:0032271 103 53 0,000 0,1285194 0,13884943 ! negative regulation of cytoskeleton organization GO:0051494 124 54 0,000 0,13078042 0,14122877 ! generation of a signal involved in cell-cell signaling GO:0003001 95 54 0,000 0,13078042 0,14116541 ! cell recognition GO:0008037 85 54 0,000 0,13078042 0,14110211 ! heterocycle catabolic process GO:0046700 85 54 0,000 0,13078042 0,14103886 ! glutamine family amino acid metabolic process GO:0009064 78 54 0,000 0,13078042 0,14097567 ! cellular amino acid derivative biosynthetic process GO:0042398 90 54 0,000 0,13078042 0,14091254 ! chloride transport GO:0006821 90 55 0,000 0,13303566 0,14327833 ! positive regulation of caspase activity GO:0043280 95 55 0,000 0,13303566 0,14321423 GO:0010952|positive regulation of peptidase activity, ! glucose catabolic process GO:0006007 82 55 0,000 0,13303566 0,14315018 ! cellular polysaccharide metabolic process GO:0044264 86 55 0,000 0,13303566 0,14308619 ! sulfur compound biosynthetic process GO:0044272 93 55 0,000 0,13303566 0,14302225 ! aging GO:0007568 103 55 0,000 0,13303566 0,14295837 ! gastrulation GO:0007369 112 55 0,000 0,13303566 0,14289455 ! regulation of multicellular organism growth GO:0040014 85 55 0,000 0,13303566 0,14283079 ! RNA elongation GO:0006354 79 55 0,000 0,13303566 0,14276708 ! nuclear export GO:0051168 97 55 0,000 0,13303566 0,14270343 ! negative regulation of cell motion GO:0051271 134 55 0,000 0,13303566 0,14263984 ! regulation of actin filament length GO:0030832 105 56 0,000 0,13528512 0,14498708 ! sensory perception of smell GO:0007608 80 56 0,000 0,13528512 0,14492253 ! glycosaminoglycan metabolic process GO:0030203 91 56 0,000 0,13528512 0,14485803 ! nucleotide-excision repair GO:0006289 83 56 0,000 0,13528512 0,14479359 ! proton transport GO:0015992 94 56 0,000 0,13528512 0,14472921 ! positive regulation of organelle organization GO:0010638 100 56 0,000 0,13528512 0,14466489 ! regulation of bone remodeling GO:0046850 137 57 0,000 0,13752881 0,14699881 ! maintenance of location GO:0051235 118 57 0,000 0,13752881 0,14693354 ! hydrogen transport GO:0006818 97 58 0,000 0,13976676 0,14925825 ! regulation of tissue remodeling GO:0034103 140 58 0,000 0,13976676 0,14919203 ! regulation of endocytosis GO:0030100 91 58 0,000 0,13976676 0,14912587 ! adult behavior GO:0030534 99 58 0,000 0,13976676 0,14905977 ! positive regulation of secretion GO:0051047 95 59 0,000 0,14199898 0,1513733 ! regulation of cellular component size GO:0032535 109 59 0,000 0,14199898 0,15130626 ! skeletal system morphogenesis GO:0048705 105 59 0,000 0,14199898 0,15123929 ! regulation of Rab protein signal transduction GO:0032483 92 59 0,000 0,14199898 0,15117237 GO:0032313|regulation of Rab GTPase activity, ! cytokine-mediated signaling pathway GO:0019221 97 59 0,000 0,14199898 0,1511055 ! DNA catabolic process GO:0006308 86 59 0,000 0,14199898 0,1510387 ! integrin-mediated signaling pathway GO:0007229 135 59 0,000 0,14199898 0,15097196 ! regulation of neurotransmitter levels GO:0001505 97 60 0,000 0,14422548 0,15327142 ! DNA damage response, signal transduction GO:0042770 128 60 0,000 0,14422548 0,15320375 ! nucleoside metabolic process GO:0009116 81 60 0,000 0,14422548 0,15313614 ! regulation of heart contraction GO:0008016 110 60 0,000 0,14422548 0,15306859 ! camera-type eye development GO:0043010 116 60 0,000 0,14422548 0,1530011 ! negative regulation of response to stimulus GO:0048585 100 60 0,000 0,14422548 0,15293367 ! kidney development GO:0001822 122 60 0,000 0,14422548 0,1528663 ! glycerophospholipid biosynthetic process GO:0046474 105 61 0,000 0,14644627 0,1551518 ! mesoderm development GO:0007498 119 61 0,000 0,14644627 0,15508351 ! sphingolipid metabolic process GO:0006665 107 61 0,000 0,14644627 0,15501528 ! ear development GO:0043583 103 62 0,000 0,14866138 0,1572908 ! water-soluble vitamin metabolic process GO:0006767 95 62 0,000 0,14866138 0,15722166 ! gonad development GO:0008406 98 62 0,000 0,14866138 0,15715258 ! regulation of homeostatic process GO:0032844 134 62 0,000 0,14866138 0,15708356 ! regulation of mitosis GO:0007088 105 63 0,000 0,15087081 0,15934818 GO:0051783|regulation of nuclear division, ! cellular amino acid catabolic process GO:0009063 101 63 0,000 0,15087081 0,15927826 ! oxygen and reactive oxygen species metabolic process GO:0006800 93 64 0,000 0,15307458 0,16153396 ! cell redox homeostasis GO:0045454 102 64 0,000 0,15307458 0,16146314 ! lymphocyte mediated immunity GO:0002449 114 64 0,000 0,15307458 0,16139239 ! multicellular organism reproduction GO:0032504 111 64 0,000 0,15307458 0,16132169 GO:0048609|reproductive process in a multicellular organism, ! single fertilization GO:0007338 75 64 0,000 0,15307458 0,16125106 ! aminoglycan metabolic process GO:0006022 102 65 0,000 0,1552727 0,16349502 ! regulation of cytokine biosynthetic process GO:0042035 95 65 0,000 0,1552727 0,1634235 ! germ cell development GO:0007281 118 65 0,000 0,1552727 0,16335204 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 113 66 0,000 0,15746519 0,16558621 ! actin filament organization GO:0007015 148 66 0,000 0,15746519 0,16551387 ! extracellular matrix organization GO:0030198 133 66 0,000 0,15746519 0,16544159 ! secondary metabolic process GO:0019748 116 66 0,000 0,15746519 0,16536938 ! developmental maturation GO:0021700 116 66 0,000 0,15746519 0,16529723 ! regulation of cellular response to stress GO:0080135 128 67 0,000 0,15965206 0,16751978 ! chromosome segregation GO:0007059 113 67 0,000 0,15965206 0,16744676 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 109 67 0,000 0,15965206 0,1673738 ! homeostasis of number of cells GO:0048872 114 67 0,000 0,15965206 0,1673009 ! hexose catabolic process GO:0019320 104 67 0,000 0,15965206 0,16722806 ! positive regulation of T cell activation GO:0050870 109 67 0,000 0,15965206 0,16715529 ! adaptive immune response GO:0002250 119 67 0,000 0,15965206 0,16708258 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! activation of immune response GO:0002253 105 67 0,000 0,15965206 0,16700994 ! amino acid transport GO:0006865 125 68 0,000 0,16183333 0,16921816 ! membrane lipid metabolic process GO:0006643 117 68 0,000 0,16183333 0,16914465 ! negative regulation of ligase activity GO:0051352 112 68 0,000 0,16183333 0,16907121 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! protein maturation by peptide bond cleavage GO:0051605 105 68 0,000 0,16183333 0,16899783 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 110 68 0,000 0,16183333 0,16892451 ! cell cycle checkpoint GO:0000075 137 69 0,000 0,16400901 0,17112128 ! cAMP-mediated signaling GO:0019933 120 69 0,000 0,16400901 0,17104711 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 112 69 0,000 0,16400901 0,170973 ! urogenital system development GO:0001655 137 69 0,000 0,16400901 0,17089895 ! glycerolipid biosynthetic process GO:0045017 118 69 0,000 0,16400901 0,17082497 ! coenzyme biosynthetic process GO:0009108 102 69 0,000 0,16400901 0,17075105 ! antigen processing and presentation GO:0019882 104 69 0,000 0,16400901 0,1706772 ! amine catabolic process GO:0009310 117 71 0,000 0,16834366 0,17511234 ! reproductive structure development GO:0048608 113 71 0,000 0,16834366 0,17503666 ! humoral immune response GO:0006959 109 71 0,000 0,16834366 0,17496106 ! B cell activation GO:0042113 160 71 0,000 0,16834366 0,17488551 ! regulation of MAPKKK cascade GO:0043408 142 71 0,000 0,16834366 0,17481003 ! regulation of immune effector process GO:0002697 137 71 0,000 0,16834366 0,17473462 ! acute inflammatory response GO:0002526 113 72 0,000 0,17050265 0,17689926 ! positive regulation of protein amino acid phosphorylation GO:0001934 108 72 0,000 0,17050265 0,17682301 ! carbohydrate transport GO:0008643 110 72 0,000 0,17050265 0,17674683 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 115 72 0,000 0,17050265 0,17667071 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 118 72 0,000 0,17050265 0,17659466 ! regulation of blood pressure GO:0008217 125 73 0,000 0,17265612 0,17874811 ! lipoprotein metabolic process GO:0042157 131 73 0,000 0,17265612 0,17867123 ! fertilization GO:0009566 90 73 0,000 0,17265612 0,17859442 ! transition metal ion transport GO:0000041 126 74 0,000 0,17480406 0,18073854 ! neurotransmitter transport GO:0006836 123 74 0,000 0,17480406 0,1806609 ! exocytosis GO:0006887 133 74 0,000 0,17480406 0,18058333 ! regulation of actin cytoskeleton organization GO:0032956 149 74 0,000 0,17480406 0,18050582 ! leukocyte mediated immunity GO:0002443 128 74 0,000 0,17480406 0,18042839 ! eye development GO:0001654 143 74 0,000 0,17480406 0,18035102 ! cell-matrix adhesion GO:0007160 163 75 0,000 0,1769465 0,18248319 ! elevation of cytosolic calcium ion concentration GO:0007204 133 75 0,000 0,1769465 0,182405 ! regulation of vesicle-mediated transport GO:0060627 119 75 0,000 0,1769465 0,18232689 ! rhythmic process GO:0048511 128 75 0,000 0,1769465 0,18224884 ! lymphocyte differentiation GO:0030098 167 75 0,000 0,1769465 0,18217085 ! cytosolic calcium ion homeostasis GO:0051480 135 76 0,000 0,17908345 0,18429203 ! development of primary sexual characteristics GO:0045137 124 76 0,000 0,17908345 0,18421324 ! defense response to bacterium GO:0042742 89 76 0,000 0,17908345 0,18413452 ! monosaccharide catabolic process GO:0046365 115 76 0,000 0,17908345 0,18405586 ! neuropeptide signaling pathway GO:0007218 107 77 0,000 0,18121492 0,18616699 ! regulation of actin filament-based process GO:0032970 152 77 0,000 0,18121492 0,18608753 ! positive regulation of ligase activity GO:0051351 124 77 0,000 0,18121492 0,18600814 ! blood coagulation GO:0007596 146 78 0,000 0,18334092 0,18811013 GO:0050817|coagulation, ! transcription initiation from RNA polymerase II promoter GO:0006367 121 78 0,000 0,18334092 0,18802995 ! negative regulation of organelle organization GO:0010639 161 78 0,000 0,18334092 0,18794984 ! response to steroid hormone stimulus GO:0048545 137 78 0,000 0,18334092 0,18786979 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 154 79 0,000 0,18546148 0,18996182 ! sensory perception of chemical stimulus GO:0007606 109 79 0,000 0,18546148 0,18988099 ! regulation of ubiquitin-protein ligase activity GO:0051438 133 79 0,000 0,18546148 0,18980022 ! regulation of synaptic transmission GO:0050804 134 79 0,000 0,18546148 0,18971952 ! regulation of adenylate cyclase activity GO:0045761 156 80 0,000 0,1875766 0,19180166 ! response to metal ion GO:0010038 140 80 0,000 0,1875766 0,19172018 ! cellular lipid catabolic process GO:0044242 134 80 0,000 0,1875766 0,19163877 ! protein import into nucleus GO:0006606 158 80 0,000 0,1875766 0,19155743 ! inorganic anion transport GO:0015698 138 80 0,000 0,1875766 0,19147616 ! T cell activation GO:0042110 168 81 0,000 0,1896863 0,1935476 ! digestion GO:0007586 112 81 0,000 0,1896863 0,19346555 ! cell-substrate adhesion GO:0031589 171 81 0,000 0,1896863 0,19338358 ! nuclear import GO:0051170 161 81 0,000 0,1896863 0,19330167 ! regulation of cAMP biosynthetic process GO:0030817 161 82 0,000 0,19179059 0,19536332 ! response to drug GO:0042493 143 82 0,000 0,19179059 0,19528064 ! regulation of cyclase activity GO:0031279 159 82 0,000 0,19179059 0,19519804 ! regulation of lyase activity GO:0051339 160 83 0,000 0,19388949 0,19725078 ! regulation of cAMP metabolic process GO:0030814 168 84 0,000 0,195983 0,19929632 ! hemostasis GO:0007599 158 84 0,000 0,195983 0,19921213 ! regulation of ligase activity GO:0051340 142 84 0,000 0,195983 0,199128 ! regulation of transmission of nerve impulse GO:0051969 141 84 0,000 0,195983 0,19904394 ! amine biosynthetic process GO:0009309 138 86 0,000 0,20015394 0,20319426 ! response to inorganic substance GO:0010035 153 86 0,000 0,20015394 0,20310856 ! oxidative phosphorylation GO:0006119 133 86 0,000 0,20015394 0,20302293 ! tube morphogenesis GO:0035239 176 86 0,000 0,20015394 0,20293737 ! mitochondrion organization GO:0007005 148 86 0,000 0,20015394 0,20285189 ! alcohol catabolic process GO:0046164 130 86 0,000 0,20015394 0,20276648 ! amine transport GO:0015837 155 86 0,000 0,20015394 0,20268114 ! regulation of nucleotide biosynthetic process GO:0030808 170 87 0,000 0,2022314 0,20469867 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! nitrogen compound catabolic process GO:0044270 143 87 0,000 0,2022314 0,20461259 ! protein localization in nucleus GO:0034504 176 87 0,000 0,2022314 0,20452658 ! cellular respiration GO:0045333 135 88 0,000 0,20430352 0,20653541 ! positive regulation of protein modification process GO:0031401 136 88 0,000 0,20430352 0,20644867 ! regulation of neurological system process GO:0031644 148 88 0,000 0,20430352 0,206362 ! ATP biosynthetic process GO:0006754 159 88 0,000 0,20430352 0,2062754 ! cellular defense response GO:0006968 114 89 0,000 0,20637033 0,20827476 ! regulation of cell morphogenesis GO:0022604 215 89 0,000 0,20637033 0,20818743 ! regulation of cyclic nucleotide metabolic process GO:0030799 179 90 0,000 0,20843185 0,21017897 ! regulation of cell cycle process GO:0010564 149 90 0,000 0,20843185 0,21009092 ! sex differentiation GO:0007548 145 90 0,000 0,20843185 0,21000294 ! cofactor biosynthetic process GO:0051188 139 91 0,000 0,21048807 0,2119859 ! regulation of defense response GO:0031347 149 92 0,000 0,21253903 0,21396188 ! phospholipid biosynthetic process GO:0008654 167 92 0,000 0,21253903 0,2138724 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 160 93 0,000 0,21458472 0,21584065 GO:0010498|proteasomal protein catabolic process, ! regulation of nucleotide metabolic process GO:0006140 182 93 0,000 0,21458472 0,21575046 ! carbohydrate biosynthetic process GO:0016051 141 93 0,000 0,21458472 0,21566033 ! biogenic amine metabolic process GO:0006576 155 94 0,000 0,21662517 0,21762011 ! transcription initiation GO:0006352 153 94 0,000 0,21662517 0,21752928 ! regulation of Rho protein signal transduction GO:0035023 213 95 0,000 0,21866038 0,21948139 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 167 96 0,000 0,22069038 0,22142663 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! mRNA transport GO:0051028 169 96 0,000 0,22069038 0,22133433 ! positive regulation of immune response GO:0050778 156 96 0,000 0,22069038 0,2212421 ! ribonucleoside triphosphate biosynthetic process GO:0009201 168 97 0,000 0,22271516 0,22317896 ! response to virus GO:0009615 160 98 0,000 0,22473476 0,22510901 ! nucleoside triphosphate biosynthetic process GO:0009142 169 98 0,000 0,22473476 0,22501533 ! carboxylic acid catabolic process GO:0046395 156 98 0,000 0,22473476 0,22492173 GO:0016054|organic acid catabolic process, ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 155 99 0,000 0,22674917 0,22684346 ! Golgi vesicle transport GO:0048193 207 99 0,000 0,22674917 0,22674917