pValThreshold = 0.5 scoreFile = /home/data/iti/output/study-er-neg-stratification/runs-Desmedt//out-0.3-01-0.03-300-Desmedt//go_data/6390-Wang-ermine.txt scoreCol = 2 classFile = /home/data/annotations/gene-ontology/go_daily-termdb.rdf-xml.gz bigIsBetter = true doLog = false annotFile = /home/data/annotations/ermineJ.data/HG-U133A_B_Plus_2_bioProcess.an.txt.gz classScoreMethod = 0 filterNonSpecific = false # #! Name ID Probes NumGenes RawScore Pval CorrectedPvalue Same as GeneMembers ! regulation of intracellular protein transport GO:0033157 59 35 4,000 9,289E-07 2,136E-03 ! regulation of granulocyte macrophage colony-stimulating factor production GO:0032645 5 5 2,000 1,31E-06 1,506E-03 GO:0045423|regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, GO:0045425|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process, ! positive regulation of nucleocytoplasmic transport GO:0046824 27 17 3,000 1,485E-06 1,139E-03 ! regulation of nucleocytoplasmic transport GO:0046822 70 42 4,000 2,366E-06 1,36E-03 ! positive regulation of intracellular transport GO:0032388 29 19 3,000 2,4E-06 1,104E-03 ! regulation of protein export from nucleus GO:0046825 6 6 2,000 2,61E-06 1E-03 ! ER overload response GO:0006983 7 6 2,000 2,61E-06 8,574E-04 ! positive regulation of T-helper 1 cell differentiation GO:0045627 7 6 2,000 2,61E-06 7,503E-04 GO:0045625|regulation of T-helper 1 cell differentiation, ! response to vitamin GO:0033273 29 20 3,000 2,988E-06 7,635E-04 ! T cell activation GO:0042110 134 79 5,000 3,233E-06 7,437E-04 ! response to endoplasmic reticulum stress GO:0034976 25 21 3,000 3,676E-06 7,686E-04 ! regulation of intracellular transport GO:0032386 78 49 4,000 5,155E-06 9,881E-04 ! cell cycle arrest GO:0007050 150 86 5,000 5,314E-06 9,401E-04 ! ER-nuclear signaling pathway GO:0006984 27 23 3,000 5,396E-06 8,865E-04 ! negative regulation of cell development GO:0010721 56 24 3,000 6,45E-06 9,89E-04 GO:0050768|negative regulation of neurogenesis, ! regulation of T-helper 1 type immune response GO:0002825 9 8 2,000 7,252E-06 1,043E-03 ! negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051436 88 60 4,000 1,412E-05 1,911E-03 ! negative regulation of ligase activity GO:0051352 91 61 4,000 1,532E-05 1,958E-03 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 88 61 4,000 1,532E-05 1,855E-03 ! positive regulation of transcription factor import into nucleus GO:0042993 20 10 2,000 1,543E-05 1,774E-03 ! response to X-ray GO:0010165 16 10 2,000 1,543E-05 1,689E-03 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 22 10 2,000 1,543E-05 1,613E-03 ! detection of bacterium GO:0016045 10 10 2,000 1,543E-05 1,543E-03 ! positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051437 89 62 4,000 1,66E-05 1,591E-03 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 92 65 4,000 2,093E-05 1,926E-03 ! regulation of ubiquitin-protein ligase activity during mitotic cell cycle GO:0051439 95 65 4,000 2,093E-05 1,852E-03 ! positive regulation of ligase activity GO:0051351 99 69 4,000 2,802E-05 2,387E-03 ! positive regulation of interleukin-2 biosynthetic process GO:0045086 21 12 2,000 2,807E-05 2,306E-03 ! response to gamma radiation GO:0010332 20 12 2,000 2,807E-05 2,226E-03 ! regulation of ubiquitin-protein ligase activity GO:0051438 107 71 4,000 3,22E-05 2,469E-03 ! positive regulation of protein import into nucleus GO:0042307 23 13 2,000 3,635E-05 2,697E-03 ! positive regulation of T-helper cell differentiation GO:0045624 19 13 2,000 3,635E-05 2,613E-03 ! response to nutrient GO:0007584 104 75 4,000 4,2E-05 2,928E-03 ! regulation of ligase activity GO:0051340 114 75 4,000 4,2E-05 2,841E-03 ! regulation of protein transport GO:0051223 114 76 4,000 4,478E-05 2,943E-03 GO:0070201|regulation of establishment of protein localization, ! positive regulation of CD4-positive, alpha beta T cell differentiation GO:0043372 20 14 2,000 4,61E-05 2,945E-03 ! positive regulation of protein transport GO:0051222 55 40 3,000 5,209E-05 3,238E-03 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 118 80 4,000 5,734E-05 3,47E-03 GO:0010498|proteasomal protein catabolic process, ! regulation of interleukin-2 biosynthetic process GO:0045076 25 15 2,000 5,741E-05 3,385E-03 ! myoblast differentiation GO:0045445 27 15 2,000 5,741E-05 3,301E-03 ! centrosome cycle GO:0007098 16 15 2,000 5,741E-05 3,22E-03 ! regulation of T-helper cell differentiation GO:0045622 23 15 2,000 5,741E-05 3,144E-03 ! regulation of CD4-positive, alpha beta T cell differentiation GO:0043370 24 16 2,000 7,039E-05 3,765E-03 ! detection of biotic stimulus GO:0009595 19 16 2,000 7,039E-05 3,68E-03 ! regulation of protein localization GO:0032880 132 85 4,000 7,667E-05 3,919E-03 ! interphase of mitotic cell cycle GO:0051329 156 86 4,000 8,107E-05 4,054E-03 ! phosphatidylinositol metabolic process GO:0046488 22 17 2,000 8,516E-05 4,167E-03 ! interphase GO:0051325 159 88 4,000 9,046E-05 4,335E-03 ! response to retinoic acid GO:0032526 25 18 2,000 1,018E-04 4,779E-03 ! positive regulation of alpha-beta T cell differentiation GO:0046638 25 18 2,000 1,018E-04 4,683E-03 ! reciprocal meiotic recombination GO:0007131 31 19 2,000 1,204E-04 5,432E-03 ! calcium-independent cell-cell adhesion GO:0016338 21 19 2,000 1,204E-04 5,327E-03 ! response to vitamin A GO:0033189 26 19 2,000 1,204E-04 5,227E-03 ! regulation of interleukin-2 production GO:0032663 31 19 2,000 1,204E-04 5,13E-03 ! regulation of cyclin-dependent protein kinase activity GO:0000079 81 51 3,000 1,364E-04 5,705E-03 ! G2/M transition of mitotic cell cycle GO:0000086 33 21 2,000 1,641E-04 6,739E-03 ! cell aging GO:0007569 32 21 2,000 1,641E-04 6,621E-03 ! regulation of alpha-beta T cell differentiation GO:0046637 30 21 2,000 1,641E-04 6,507E-03 ! positive regulation of alpha-beta T cell activation GO:0046635 30 21 2,000 1,641E-04 6,397E-03 ! protein import into nucleus, translocation GO:0000060 36 22 2,000 1,893E-04 7,256E-03 ! vasculogenesis GO:0001570 33 22 2,000 1,893E-04 7,137E-03 ! microtubule organizing center organization GO:0031023 28 22 2,000 1,893E-04 7,022E-03 GO:0051297|centrosome organization, ! DNA damage response, signal transduction by p53 class mediator GO:0030330 47 22 2,000 1,893E-04 6,911E-03 ! DNA damage response, signal transduction GO:0042770 96 56 3,000 1,966E-04 7,066E-03 ! regulation of transcription factor import into nucleus GO:0042990 46 23 2,000 2,169E-04 7,674E-03 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 42 23 2,000 2,169E-04 7,558E-03 ! negative regulation of DNA replication GO:0008156 35 23 2,000 2,169E-04 7,445E-03 ! regulation of alpha-beta T cell activation GO:0046634 35 24 2,000 2,469E-04 8,352E-03 ! phosphoinositide metabolic process GO:0030384 87 60 3,000 2,57E-04 8,566E-03 ! benzene and derivative metabolic process GO:0042537 11 5 1,000 2,595E-04 8,526E-03 ! negative regulation of bone resorption GO:0045779 10 5 1,000 2,595E-04 8,406E-03 ! regulation of mitochondrial membrane permeability GO:0046902 9 5 1,000 2,595E-04 8,289E-03 ! epithelial cell proliferation GO:0050673 6 5 1,000 2,595E-04 8,175E-03 ! early endosome to late endosome transport GO:0045022 11 5 1,000 2,595E-04 8,065E-03 ! maintenance of fidelity during DNA-dependent DNA replication GO:0045005 5 5 1,000 2,595E-04 7,957E-03 ! negative regulation of gliogenesis GO:0014014 16 5 1,000 2,595E-04 7,853E-03 GO:0045686|negative regulation of glial cell differentiation, ! centrosome duplication GO:0051298 5 5 1,000 2,595E-04 7,751E-03 ! response to UV-C GO:0010225 6 5 1,000 2,595E-04 7,651E-03 ! cranial nerve morphogenesis GO:0021602 6 5 1,000 2,595E-04 7,554E-03 ! positive regulation of blood vessel endothelial cell migration GO:0043536 15 5 1,000 2,595E-04 7,46E-03 ! NAD biosynthetic process GO:0009435 7 5 1,000 2,595E-04 7,368E-03 ! meiosis GO:0007126 96 61 3,000 2,739E-04 7,684E-03 GO:0051327|M phase of meiotic cell cycle, ! cell-matrix adhesion GO:0007160 114 61 3,000 2,739E-04 7,591E-03 ! meiotic cell cycle GO:0051321 97 62 3,000 2,917E-04 7,987E-03 ! response to ionizing radiation GO:0010212 47 27 2,000 3,529E-04 9,549E-03 ! negative regulation of protein transport GO:0051224 49 27 2,000 3,529E-04 9,438E-03 ! cell-substrate adhesion GO:0031589 121 66 3,000 3,71E-04 9,808E-03 ! regulation of helicase activity GO:0051095 11 6 1,000 3,879E-04 0,01013852 ! cytokinesis during cell cycle GO:0033205 9 6 1,000 3,879E-04 0,01002461 ! male meiosis GO:0007140 7 6 1,000 3,879E-04 9,913E-03 ! N-terminal protein amino acid acetylation GO:0006474 7 6 1,000 3,879E-04 9,804E-03 ! mRNA stabilization GO:0048255 15 6 1,000 3,879E-04 9,698E-03 GO:0043489|RNA stabilization, ! response to interferon-gamma GO:0034341 12 6 1,000 3,879E-04 9,593E-03 ! activation of caspase activity by cytochrome c GO:0008635 10 6 1,000 3,879E-04 9,491E-03 ! cerebral cortex neuron differentiation GO:0021895 12 6 1,000 3,879E-04 9,391E-03 ! DNA damage response, signal transduction resulting in transcription GO:0042772 11 6 1,000 3,879E-04 9,294E-03 GO:0006978|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, ! negative regulation of neuroblast proliferation GO:0007406 18 6 1,000 3,879E-04 9,198E-03 ! axonal fasciculation GO:0007413 9 6 1,000 3,879E-04 9,104E-03 ! negative regulation of axon extension GO:0030517 13 6 1,000 3,879E-04 9,012E-03 ! blastocyst growth GO:0001832 15 6 1,000 3,879E-04 8,922E-03 ! positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 13 6 1,000 3,879E-04 8,834E-03 ! positive regulation of T cell differentiation GO:0045582 39 28 2,000 3,938E-04 8,879E-03 ! regulation of protein import into nucleus GO:0042306 53 29 2,000 4,376E-04 9,771E-03 ! steroid biosynthetic process GO:0006694 94 71 3,000 4,905E-04 0,010847 ! DNA damage checkpoint GO:0000077 53 31 2,000 5,343E-04 0,01170393 ! T-helper 1 type immune response GO:0042088 11 7 1,000 5,413E-04 0,01174415 ! vascular endothelial growth factor receptor signaling pathway GO:0048010 10 7 1,000 5,413E-04 0,0116344 ! positive regulation of mitotic cell cycle GO:0045931 11 7 1,000 5,413E-04 0,01152667 ! G1 DNA damage checkpoint GO:0031571 18 7 1,000 5,413E-04 0,01142092 ! B cell lineage commitment GO:0002326 17 7 1,000 5,413E-04 0,01131709 ! T cell lineage commitment GO:0002360 12 7 1,000 5,413E-04 0,01121514 ! response to tumor cell GO:0002347 12 7 1,000 5,413E-04 0,011115 ! neuroblast proliferation GO:0007405 13 7 1,000 5,413E-04 0,01101664 ! nicotinamide nucleotide biosynthetic process GO:0019359 9 7 1,000 5,413E-04 0,01092 ! negative regulation of DNA metabolic process GO:0051053 48 32 2,000 5,874E-04 0,0117479 ! meiosis I GO:0007127 52 32 2,000 5,874E-04 0,01164663 ! positive regulation of lymphocyte differentiation GO:0045621 45 32 2,000 5,874E-04 0,01154709 ! androgen receptor signaling pathway GO:0030521 54 33 2,000 6,437E-04 0,01254742 ! DNA integrity checkpoint GO:0031570 57 34 2,000 7,034E-04 0,01359542 ! Wnt receptor signaling pathway through beta-catenin GO:0060070 14 8 1,000 7,193E-04 0,01378567 ! positive regulation of endothelial cell migration GO:0010595 18 8 1,000 7,193E-04 0,01367174 ! regulation of gliogenesis GO:0014013 20 8 1,000 7,193E-04 0,01355967 GO:0045685|regulation of glial cell differentiation, ! phosphoinositide 3-kinase cascade GO:0014065 23 8 1,000 7,193E-04 0,01344943 ! induction of positive chemotaxis GO:0050930 14 8 1,000 7,193E-04 0,01334097 ! insulin-like growth factor receptor signaling pathway GO:0048009 14 8 1,000 7,193E-04 0,01323424 ! multicellular organism growth GO:0035264 14 8 1,000 7,193E-04 0,01312921 ! regulation of vascular permeability GO:0043114 12 8 1,000 7,193E-04 0,01302583 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 15 8 1,000 7,193E-04 0,01292406 ! receptor clustering GO:0043113 15 9 1,000 9,217E-04 0,01643263 ! oocyte differentiation GO:0009994 12 9 1,000 9,217E-04 0,01630623 GO:0048599|oocyte development, ! pyridine nucleotide biosynthetic process GO:0019363 11 9 1,000 9,217E-04 0,01618175 ! SMAD protein nuclear translocation GO:0007184 15 9 1,000 9,217E-04 0,01605916 ! lung alveolus development GO:0048286 17 9 1,000 9,217E-04 0,01593842 ! negative regulation of striated muscle development GO:0045843 11 9 1,000 9,217E-04 0,01581947 ! indolalkylamine metabolic process GO:0006586 14 9 1,000 9,217E-04 0,01570229 GO:0042434|indole derivative metabolic process, GO:0042430|indole and derivative metabolic process, ! microtubule cytoskeleton organization GO:0000226 120 84 3,000 9,257E-04 0,01565594 ! cell growth GO:0016049 61 39 2,000 1,055E-03 0,01770356 ! skeletal muscle tissue development GO:0007519 123 87 3,000 1,056E-03 0,01759185 GO:0060538|skeletal muscle organ development, ! induction of apoptosis by intracellular signals GO:0008629 67 40 2,000 1,136E-03 0,01879371 ! T cell differentiation GO:0030217 65 40 2,000 1,136E-03 0,01865947 ! double-strand break repair GO:0006302 67 40 2,000 1,136E-03 0,01852714 ! negative regulation of muscle development GO:0048635 12 10 1,000 1,148E-03 0,01859783 ! hippocampus development GO:0021766 19 10 1,000 1,148E-03 0,01846778 ! blood vessel remodeling GO:0001974 21 10 1,000 1,148E-03 0,01833953 ! peptide or protein amino-terminal blocking GO:0018409 14 10 1,000 1,148E-03 0,01821305 ! regulation of S phase of mitotic cell cycle GO:0007090 12 10 1,000 1,148E-03 0,0180883 ! platelet-derived growth factor receptor signaling pathway GO:0048008 17 10 1,000 1,148E-03 0,01796525 ! regulation of bone resorption GO:0045124 24 10 1,000 1,148E-03 0,01784387 ! negative regulation of axonogenesis GO:0050771 23 10 1,000 1,148E-03 0,01772411 ! cranial nerve development GO:0021545 12 10 1,000 1,148E-03 0,01760595 ! positive regulation of leukocyte migration GO:0002687 23 10 1,000 1,148E-03 0,01748935 ! cytoplasmic sequestering of protein GO:0051220 14 10 1,000 1,148E-03 0,01737429 ! regulation of neurogenesis GO:0050767 153 89 3,000 1,149E-03 0,01726965 ! regulation of T cell differentiation GO:0045580 59 41 2,000 1,221E-03 0,01823456 ! glycerophospholipid metabolic process GO:0006650 130 92 3,000 1,299E-03 0,01928107 ! DNA recombination GO:0006310 146 92 3,000 1,299E-03 0,01915747 ! positive regulation of cytokine biosynthetic process GO:0042108 54 42 2,000 1,31E-03 0,01919065 ! peptidyl-amino acid modification GO:0018193 147 93 3,000 1,352E-03 0,01968813 ! double-strand break repair via homologous recombination GO:0000724 16 11 1,000 1,399E-03 0,02023243 GO:0000725|recombinational repair, ! regulation of positive chemotaxis GO:0050926 17 11 1,000 1,399E-03 0,02010598 GO:0050927|positive regulation of positive chemotaxis, ! dopamine receptor signaling pathway GO:0007212 22 11 1,000 1,399E-03 0,0199811 ! positive regulation of endothelial cell proliferation GO:0001938 18 11 1,000 1,399E-03 0,01985776 ! regulation of mRNA processing GO:0050684 18 11 1,000 1,399E-03 0,01973593 ! oligodendrocyte differentiation GO:0048709 14 11 1,000 1,399E-03 0,01961559 ! regulation of intracellular pH GO:0051453 17 11 1,000 1,399E-03 0,01949671 ! actin cytoskeleton reorganization GO:0031532 21 11 1,000 1,399E-03 0,01937926 ! regulation of leukocyte migration GO:0002685 24 11 1,000 1,399E-03 0,01926322 ! aromatic amino acid family catabolic process GO:0009074 13 11 1,000 1,399E-03 0,01914855 ! biogenic amine catabolic process GO:0042402 21 11 1,000 1,399E-03 0,01903525 ! G1/S transition of mitotic cell cycle GO:0000082 87 43 2,000 1,403E-03 0,01898182 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 66 43 2,000 1,403E-03 0,01887081 ! angiogenesis GO:0001525 149 95 3,000 1,463E-03 0,01956651 ! negative regulation of cell migration GO:0030336 92 44 2,000 1,5E-03 0,01994338 ! negative regulation of cell projection organization GO:0031345 26 12 1,000 1,673E-03 0,0221117 ! histone acetylation GO:0016573 23 12 1,000 1,673E-03 0,02198535 ! autonomic nervous system development GO:0048483 23 12 1,000 1,673E-03 0,02186044 ! peptidyl-lysine modification GO:0018205 18 12 1,000 1,673E-03 0,02173693 ! regulation of mRNA stability GO:0043488 27 12 1,000 1,673E-03 0,02161481 ! regulation of blood vessel endothelial cell migration GO:0043535 33 12 1,000 1,673E-03 0,02149406 ! regulation of adaptive immune response GO:0002819 72 46 2,000 1,707E-03 0,02180744 ! response to UV GO:0009411 75 46 2,000 1,707E-03 0,02168696 ! regulation of DNA replication GO:0006275 75 48 2,000 1,93E-03 0,02439276 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 61 48 2,000 1,93E-03 0,02425946 ! regulation of lymphocyte differentiation GO:0045619 69 48 2,000 1,93E-03 0,02412762 ! N-terminal protein amino acid modification GO:0031365 18 13 1,000 1,97E-03 0,02449604 ! NAD metabolic process GO:0019674 21 13 1,000 1,97E-03 0,02436434 ! intermediate filament cytoskeleton organization GO:0045104 23 13 1,000 1,97E-03 0,02423405 ! regulation of cellular pH GO:0030641 20 13 1,000 1,97E-03 0,02410515 ! regulation of RNA stability GO:0043487 28 13 1,000 1,97E-03 0,02397761 ! regulation of axon extension GO:0030516 23 13 1,000 1,97E-03 0,02385141 ! regulation of angiogenesis GO:0045765 94 49 2,000 2,048E-03 0,02466767 ! integrin-mediated signaling pathway GO:0007229 81 49 2,000 2,048E-03 0,0245392 ! skeletal muscle fiber development GO:0048741 73 50 2,000 2,171E-03 0,02587426 ! regulation of S phase GO:0033261 18 14 1,000 2,291E-03 0,02716181 ! phosphoinositide phosphorylation GO:0046854 21 14 1,000 2,291E-03 0,02702252 ! negative regulation of bone remodeling GO:0046851 26 14 1,000 2,291E-03 0,02688465 ! limbic system development GO:0021761 25 14 1,000 2,291E-03 0,02674818 ! cellular response to starvation GO:0009267 21 14 1,000 2,291E-03 0,02661309 ! positive regulation of specific transcription from RNA polymerase II promoter GO:0010552 21 14 1,000 2,291E-03 0,02647936 ! G1/S transition checkpoint GO:0031575 33 14 1,000 2,291E-03 0,02634696 ! intermediate filament-based process GO:0045103 24 14 1,000 2,291E-03 0,02621588 ! axon cargo transport GO:0008088 27 14 1,000 2,291E-03 0,0260861 ! release of cytochrome c from mitochondria GO:0001836 23 14 1,000 2,291E-03 0,0259576 ! muscle fiber development GO:0048747 74 51 2,000 2,298E-03 0,02591288 ! positive regulation of cell migration GO:0030335 92 51 2,000 2,298E-03 0,02578648 ! regulation of protein catabolic process GO:0042176 77 51 2,000 2,298E-03 0,0256613 ! negative regulation of cell motion GO:0051271 104 51 2,000 2,298E-03 0,02553733 ! aging GO:0007568 79 52 2,000 2,43E-03 0,02687089 ! nucleotide-excision repair GO:0006289 64 52 2,000 2,43E-03 0,02674232 ! embryonic forelimb morphogenesis GO:0035115 17 15 1,000 2,635E-03 0,02885598 ! lipid phosphorylation GO:0046834 23 15 1,000 2,635E-03 0,02871922 ! negative regulation of nucleocytoplasmic transport GO:0046823 27 15 1,000 2,635E-03 0,02858375 ! peptidyl-serine phosphorylation GO:0018105 23 15 1,000 2,635E-03 0,02844955 ! neuron recognition GO:0008038 22 15 1,000 2,635E-03 0,02831661 ! cellular amino acid derivative catabolic process GO:0042219 27 15 1,000 2,635E-03 0,02818491 ! negative regulation of tissue remodeling GO:0034104 27 15 1,000 2,635E-03 0,02805442 ! positive regulation of neuron apoptosis GO:0043525 29 15 1,000 2,635E-03 0,02792514 ! detection of external stimulus GO:0009581 66 54 2,000 2,707E-03 0,02856299 ! protein amino acid acetylation GO:0006473 28 16 1,000 3,001E-03 0,03151738 ! patterning of blood vessels GO:0001569 24 16 1,000 3,001E-03 0,03137412 ! cellular response to unfolded protein GO:0034620 19 16 1,000 3,001E-03 0,03123215 GO:0030968|endoplasmic reticulum unfolded protein response, ! oogenesis GO:0048477 23 16 1,000 3,001E-03 0,03109147 ! nerve development GO:0021675 18 16 1,000 3,001E-03 0,03095204 ! positive regulation of cell motion GO:0051272 99 56 2,000 3,003E-03 0,03083687 ! regulation of cytokine biosynthetic process GO:0042035 76 58 2,000 3,318E-03 0,03392114 ! steroid hormone receptor signaling pathway GO:0030518 96 58 2,000 3,318E-03 0,03377105 ! signal complex assembly GO:0007172 29 17 1,000 3,39E-03 0,03434581 ! forelimb morphogenesis GO:0035136 19 17 1,000 3,39E-03 0,03419517 ! negative regulation of protein catabolic process GO:0042177 26 17 1,000 3,39E-03 0,03404585 ! negative regulation of intracellular transport GO:0032387 29 17 1,000 3,39E-03 0,03389782 ! peptidyl-serine modification GO:0018209 27 17 1,000 3,39E-03 0,03375108 ! aromatic compound catabolic process GO:0019439 22 17 1,000 3,39E-03 0,0336056 ! negative regulation of homeostatic process GO:0032845 28 17 1,000 3,39E-03 0,03346137 ! lung development GO:0030324 94 59 2,000 3,483E-03 0,034237 ! inhibition of adenylate cyclase activity by G-protein signaling GO:0007193 25 18 1,000 3,801E-03 0,03719911 ! apoptotic mitochondrial changes GO:0008637 29 18 1,000 3,801E-03 0,03704149 ! pigmentation during development GO:0048066 31 18 1,000 3,801E-03 0,0368852 ! somitogenesis GO:0001756 24 18 1,000 3,801E-03 0,03673022 ! cellular response to nutrient levels GO:0031669 27 18 1,000 3,801E-03 0,03657653 ! negative regulation of neuron differentiation GO:0045665 24 18 1,000 3,801E-03 0,03642413 ! cellular monovalent inorganic cation homeostasis GO:0030004 28 18 1,000 3,801E-03 0,03627299 ! negative regulation of cell growth GO:0030308 106 62 2,000 4,008E-03 0,03808905 ! respiratory tube development GO:0030323 99 62 2,000 4,008E-03 0,0379323 ! regulation of transcription factor activity GO:0051090 97 63 2,000 4,192E-03 0,03951946 GO:0090046|regulation of transcription regulator activity, ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 92 63 2,000 4,192E-03 0,03935816 ! intracellular receptor-mediated signaling pathway GO:0030522 104 63 2,000 4,192E-03 0,03919816 ! positive regulation of protein catabolic process GO:0045732 23 19 1,000 4,234E-03 0,03942367 ! negative regulation of epithelial cell proliferation GO:0050680 34 19 1,000 4,234E-03 0,0392647 ! response to starvation GO:0042594 30 19 1,000 4,234E-03 0,03910701 ! plasma membrane fusion GO:0045026 23 19 1,000 4,234E-03 0,03895059 ! regulation of endothelial cell migration GO:0010594 40 19 1,000 4,234E-03 0,0387954 ! negative regulation of angiogenesis GO:0016525 36 19 1,000 4,234E-03 0,03864145 ! aromatic amino acid family metabolic process GO:0009072 24 19 1,000 4,234E-03 0,03848872 ! regulation of microtubule polymerization or depolymerization GO:0031110 44 19 1,000 4,234E-03 0,03833719 ! protein stabilization GO:0050821 26 19 1,000 4,234E-03 0,03818685 ! cell cycle checkpoint GO:0000075 108 64 2,000 4,382E-03 0,03937381 ! negative regulation of cell size GO:0045792 108 64 2,000 4,382E-03 0,0392206 ! positive regulation of protein amino acid phosphorylation GO:0001934 87 64 2,000 4,382E-03 0,03906858 ! respiratory system development GO:0060541 100 64 2,000 4,382E-03 0,03891774 ! regulation of caspase activity GO:0043281 97 65 2,000 4,578E-03 0,04049417 ! positive regulation of T cell activation GO:0050870 94 65 2,000 4,578E-03 0,04033901 ! protein oligomerization GO:0051259 100 65 2,000 4,578E-03 0,04018505 ! microtubule-based transport GO:0010970 37 20 1,000 4,688E-03 0,04100201 ! hindlimb morphogenesis GO:0035137 32 20 1,000 4,688E-03 0,0408467 ! pallium development GO:0021543 38 20 1,000 4,688E-03 0,04069256 ! positive regulation of locomotion GO:0040017 35 20 1,000 4,688E-03 0,04053958 GO:0048520|positive regulation of behavior, GO:0050921|positive regulation of chemotaxis, ! water-soluble vitamin biosynthetic process GO:0042364 22 20 1,000 4,688E-03 0,04038775 ! regulation of endopeptidase activity GO:0052548 99 67 2,000 4,983E-03 0,04276848 ! regulation of neuron differentiation GO:0045664 107 67 2,000 4,983E-03 0,04260949 ! protein amino acid acylation GO:0043543 37 21 1,000 5,165E-03 0,04399597 ! regulation of chemotaxis GO:0050920 36 21 1,000 5,165E-03 0,04383362 ! dendrite development GO:0016358 35 21 1,000 5,165E-03 0,04367247 ! regulation of specific transcription from RNA polymerase II promoter GO:0010551 33 21 1,000 5,165E-03 0,04351249 ! cellular response to extracellular stimulus GO:0031668 32 21 1,000 5,165E-03 0,04335369 ! response to cytokine stimulus GO:0034097 47 21 1,000 5,165E-03 0,04319604 ! positive regulation of phosphorylation GO:0042327 102 70 2,000 5,632E-03 0,04693189 ! regulation of catabolic process GO:0009894 106 70 2,000 5,632E-03 0,04676246 ! regulation of fibroblast proliferation GO:0048145 35 22 1,000 5,662E-03 0,04684627 ! viral genome replication GO:0019079 29 22 1,000 5,662E-03 0,04667837 ! dicarboxylic acid metabolic process GO:0043648 33 22 1,000 5,662E-03 0,04651166 ! barbed-end actin filament capping GO:0051016 33 22 1,000 5,662E-03 0,04634614 GO:0051693|actin filament capping, ! regulation of behavior GO:0050795 38 22 1,000 5,662E-03 0,04618179 ! vitamin biosynthetic process GO:0009110 24 22 1,000 5,662E-03 0,0460186 ! blastocyst development GO:0001824 37 22 1,000 5,662E-03 0,04585656 ! neural tube closure GO:0001843 33 22 1,000 5,662E-03 0,04569566 GO:0060606|tube closure, GO:0035148|tube lumen formation, ! protein tetramerization GO:0051262 39 22 1,000 5,662E-03 0,04553589 ! muscle cell differentiation GO:0042692 104 71 2,000 5,859E-03 0,04695087 ! lymphocyte differentiation GO:0030098 113 71 2,000 5,859E-03 0,04678784 ! regulation of peptidase activity GO:0052547 106 72 2,000 6,091E-03 0,04847417 ! positive regulation of phosphorus metabolic process GO:0010562 107 72 2,000 6,091E-03 0,04830701 GO:0045937|positive regulation of phosphate metabolic process, ! response to hypoxia GO:0001666 132 72 2,000 6,091E-03 0,04814101 ! peptidyl-tyrosine phosphorylation GO:0018108 35 23 1,000 6,181E-03 0,04868517 ! negative regulation of phosphorylation GO:0042326 41 23 1,000 6,181E-03 0,04851901 ! negative regulation of catabolic process GO:0009895 34 23 1,000 6,181E-03 0,04835398 ! negative regulation of transport GO:0051051 116 73 2,000 6,329E-03 0,04934131 ! tube morphogenesis GO:0035239 118 73 2,000 6,329E-03 0,04917461 ! response to oxygen levels GO:0070482 137 74 2,000 6,572E-03 0,05089201 ! protein import into nucleus GO:0006606 118 74 2,000 6,572E-03 0,05072123 ! positive regulation of lymphocyte activation GO:0051251 108 74 2,000 6,572E-03 0,05055159 ! insulin receptor signaling pathway GO:0008286 40 24 1,000 6,72E-03 0,05152269 ! regulation of endothelial cell proliferation GO:0001936 46 24 1,000 6,72E-03 0,05135152 ! mitochondrial membrane organization GO:0007006 39 24 1,000 6,72E-03 0,05118148 ! receptor metabolic process GO:0043112 37 24 1,000 6,72E-03 0,05101256 ! primary neural tube formation GO:0014020 35 24 1,000 6,72E-03 0,05084476 ! base-excision repair GO:0006284 31 24 1,000 6,72E-03 0,05067805 ! negative regulation of growth GO:0045926 123 75 2,000 6,82E-03 0,05126415 ! nuclear import GO:0051170 121 75 2,000 6,82E-03 0,05109716 ! regulation of cell morphogenesis GO:0022604 140 76 2,000 7,075E-03 0,05282943 ! negative regulation of actin filament depolymerization GO:0030835 36 25 1,000 7,28E-03 0,05419082 ! negative regulation of actin filament polymerization GO:0030837 36 25 1,000 7,28E-03 0,05401601 ! negative regulation of phosphorus metabolic process GO:0010563 45 25 1,000 7,28E-03 0,05384232 GO:0045936|negative regulation of phosphate metabolic process, ! peptidyl-tyrosine modification GO:0018212 37 25 1,000 7,28E-03 0,05366975 ! regulation of DNA binding GO:0051101 119 77 2,000 7,334E-03 0,05389424 ! positive regulation of protein modification process GO:0031401 107 78 2,000 7,6E-03 0,05566624 ! positive regulation of smooth muscle cell proliferation GO:0048661 40 26 1,000 7,861E-03 0,05739692 ! regulation of pH GO:0006885 36 26 1,000 7,861E-03 0,05721528 ! epidermal growth factor receptor signaling pathway GO:0007173 41 26 1,000 7,861E-03 0,05703479 ! regulation of microtubule cytoskeleton organization GO:0070507 53 26 1,000 7,861E-03 0,05685544 ! nicotinamide metabolic process GO:0006769 39 26 1,000 7,861E-03 0,05667721 GO:0046496|nicotinamide nucleotide metabolic process, ! negative regulation of protein polymerization GO:0032272 38 26 1,000 7,861E-03 0,05650009 ! protein localization in nucleus GO:0034504 133 80 2,000 8,147E-03 0,05837585 ! positive regulation of cell activation GO:0050867 120 81 2,000 8,43E-03 0,06021093 GO:0002696|positive regulation of leukocyte activation, ! alkaloid metabolic process GO:0009820 40 27 1,000 8,462E-03 0,06025231 ! regulation of actin filament depolymerization GO:0030834 39 27 1,000 8,462E-03 0,06006635 ! negative regulation of transcription regulator activity GO:0090048 47 27 1,000 8,462E-03 0,05988153 GO:0043433|negative regulation of transcription factor activity, ! detection of stimulus GO:0051606 108 82 2,000 8,718E-03 0,06150399 ! negative regulation of protein complex assembly GO:0031333 42 28 1,000 9,082E-03 0,06388033 ! response to organic cyclic substance GO:0014070 47 28 1,000 9,082E-03 0,06368557 ! pyridine nucleotide metabolic process GO:0019362 41 28 1,000 9,082E-03 0,063492 ! neural tube formation GO:0001841 41 28 1,000 9,082E-03 0,0632996 ! positive regulation of catabolic process GO:0009896 40 28 1,000 9,082E-03 0,06310836 ! regulation of DNA metabolic process GO:0051052 135 85 2,000 9,616E-03 0,06661641 ! anterior/posterior pattern formation GO:0009952 124 85 2,000 9,616E-03 0,06641636 ! regulation of axonogenesis GO:0050770 51 29 1,000 9,722E-03 0,06695101 ! telencephalon development GO:0021537 52 29 1,000 9,722E-03 0,06675116 ! tissue homeostasis GO:0001894 42 29 1,000 9,722E-03 0,0665525 GO:0048871|multicellular organismal homeostasis, ! Wnt receptor signaling pathway GO:0016055 130 87 2,000 0,0102438 0,06991314 ! embryonic skeletal system morphogenesis GO:0048704 42 30 1,000 0,01038231 0,07064887 ! hindbrain development GO:0030902 45 30 1,000 0,01038231 0,07044047 ! embryonic epithelial tube formation GO:0001838 44 30 1,000 0,01038231 0,07023329 ! regulation of microtubule-based process GO:0032886 58 30 1,000 0,01038231 0,07002733 ! regulation of T cell activation GO:0050863 128 89 2,000 0,01089499 0,07327039 ! mammary gland development GO:0030879 57 31 1,000 0,01106148 0,07417322 ! glial cell differentiation GO:0010001 55 31 1,000 0,01106148 0,0739576 ! xenobiotic metabolic process GO:0006805 44 31 1,000 0,01106148 0,07374323 ! maintenance of protein location in cell GO:0032507 60 31 1,000 0,01106148 0,0735301 ! segmentation GO:0035282 41 31 1,000 0,01106148 0,0733182 ! regulation of striated muscle tissue development GO:0016202 47 31 1,000 0,01106148 0,07310751 ! positive regulation of gene-specific transcription GO:0043193 47 31 1,000 0,01106148 0,07289804 ! leukocyte differentiation GO:0002521 143 90 2,000 0,01122938 0,07379309 ! regulation of muscle development GO:0048634 48 32 1,000 0,01175976 0,07705824 ! monovalent inorganic cation homeostasis GO:0055067 45 32 1,000 0,01175976 0,07683932 ! regulation of protein stability GO:0031647 48 32 1,000 0,01175976 0,07662165 ! regulation of cytoskeleton organization GO:0051493 154 93 2,000 0,01226797 0,07970714 ! negative regulation of adenylate cyclase activity GO:0007194 48 33 1,000 0,01247692 0,08083638 GO:0051350|negative regulation of lyase activity, GO:0031280|negative regulation of cyclase activity, ! female gonad development GO:0008585 49 33 1,000 0,01247692 0,08060932 ! negative regulation of DNA binding GO:0043392 54 33 1,000 0,01247692 0,08038352 ! negative regulation of hydrolase activity GO:0051346 50 33 1,000 0,01247692 0,08015898 ! cytokinesis GO:0000910 52 33 1,000 0,01247692 0,0799357 ! regulation of binding GO:0051098 151 95 2,000 0,01299002 0,08299181 ! regulation of smooth muscle cell proliferation GO:0048660 54 34 1,000 0,01321276 0,08418105 ! regulation of neuron projection development GO:0010975 63 34 1,000 0,01321276 0,0839485 ! mitotic cell cycle checkpoint GO:0007093 63 34 1,000 0,01321276 0,08371724 ! neuron migration GO:0001764 46 34 1,000 0,01321276 0,08348725 ! female gamete generation GO:0007292 43 34 1,000 0,01321276 0,08325851 ! dorsal/ventral pattern formation GO:0009953 44 34 1,000 0,01321276 0,08303103 ! cellular response to insulin stimulus GO:0032869 52 34 1,000 0,01321276 0,08280479 ! regulation of cell morphogenesis involved in differentiation GO:0010769 62 34 1,000 0,01321276 0,08257978 ! in utero embryonic development GO:0001701 147 96 2,000 0,01335999 0,08327367 ! response to light stimulus GO:0009416 153 96 2,000 0,01335999 0,08304861 ! maintenance of protein location GO:0045185 65 35 1,000 0,01396708 0,08658838 ! glycogen metabolic process GO:0005977 48 35 1,000 0,01396708 0,08635562 ! protein homooligomerization GO:0051260 52 35 1,000 0,01396708 0,0861241 ! protein import GO:0017038 156 99 2,000 0,01450584 0,08920706 ! positive regulation of transcription factor activity GO:0051091 49 36 1,000 0,01473967 0,09040331 GO:0090047|positive regulation of transcription regulator activity, ! cellular amide metabolic process GO:0043603 52 36 1,000 0,01473967 0,09016288 ! negative regulation of binding GO:0051100 58 36 1,000 0,01473967 0,08992372 ! tissue remodeling GO:0048771 62 36 1,000 0,01473967 0,08968583 ! neural tube development GO:0021915 50 36 1,000 0,01473967 0,08944919 ! development of primary female sexual characteristics GO:0046545 52 36 1,000 0,01473967 0,0892138 GO:0046660|female sex differentiation, ! response to xenobiotic stimulus GO:0009410 50 36 1,000 0,01473967 0,08897964 ! glucan metabolic process GO:0044042 49 36 1,000 0,01473967 0,08874671 GO:0006073|cellular glucan metabolic process, ! Ras protein signal transduction GO:0007265 162 100 2,000 0,01489981 0,08947669 ! protein localization in organelle GO:0033365 161 100 2,000 0,01489981 0,08924367 ! amino acid activation GO:0043038 52 37 1,000 0,01553032 0,09277856 GO:0043039|tRNA aminoacylation, GO:0006418|tRNA aminoacylation for protein translation, ! oxidoreduction coenzyme metabolic process GO:0006733 52 37 1,000 0,01553032 0,0925382 ! gliogenesis GO:0042063 71 38 1,000 0,01633884 0,09710422 ! pigmentation GO:0043473 74 38 1,000 0,01633884 0,09685395 ! maintenance of location in cell GO:0051651 69 38 1,000 0,01633884 0,09660497 ! negative regulation of protein complex disassembly GO:0043242 67 39 1,000 0,01716502 0,10122961 ! morphogenesis of embryonic epithelium GO:0016331 60 39 1,000 0,01716502 0,10097071 ! regulation of epithelial cell proliferation GO:0050678 71 39 1,000 0,01716502 0,10071313 ! chromatin remodeling GO:0006338 68 39 1,000 0,01716502 0,10045686 ! developmental growth GO:0048589 62 39 1,000 0,01716502 0,1002019 ! regulation of actin filament polymerization GO:0030833 59 40 1,000 0,01800866 0,10486058 ! positive regulation of response to external stimulus GO:0032103 65 40 1,000 0,01800866 0,10459578 ! cytoskeleton-dependent intracellular transport GO:0030705 71 40 1,000 0,01800866 0,10433231 ! B cell differentiation GO:0030183 62 40 1,000 0,01800866 0,10407017 ! JAK-STAT cascade GO:0007259 53 40 1,000 0,01800866 0,10380934 ! energy reserve metabolic process GO:0006112 59 41 1,000 0,01886957 0,10850005 ! endosome transport GO:0016197 71 41 1,000 0,01886957 0,10822948 ! positive regulation of DNA binding GO:0043388 57 41 1,000 0,01886957 0,10796025 ! mitochondrial transport GO:0006839 60 42 1,000 0,01974755 0,11270316 ! branching morphogenesis of a tube GO:0048754 72 42 1,000 0,01974755 0,1124242 ! embryonic skeletal system development GO:0048706 56 42 1,000 0,01974755 0,1121466 ! regulation of cell shape GO:0008360 78 42 1,000 0,01974755 0,11187038 ! positive regulation of binding GO:0051099 59 43 1,000 0,02064241 0,11665244 ! regulation of gene-specific transcription GO:0032583 69 43 1,000 0,02064241 0,11636653 ! activation of caspase activity GO:0006919 65 43 1,000 0,02064241 0,11608201 ! DNA-dependent DNA replication GO:0006261 59 43 1,000 0,02064241 0,11579889 ! response to insulin stimulus GO:0032868 63 43 1,000 0,02064241 0,11551714 ! epithelial tube morphogenesis GO:0060562 65 43 1,000 0,02064241 0,11523676 ! regulation of cell projection organization GO:0031344 83 44 1,000 0,02155395 0,1200341 ! positive regulation of cell cycle GO:0045787 77 45 1,000 0,02248198 0,12489989 ! regulation of translational initiation GO:0006446 64 45 1,000 0,02248198 0,12459893 ! vascular process in circulatory system GO:0003018 69 45 1,000 0,02248198 0,12429941 ! cell recognition GO:0008037 58 45 1,000 0,02248198 0,12400133 ! cell maturation GO:0048469 60 45 1,000 0,02248198 0,12370468 ! protein amino acid autophosphorylation GO:0046777 80 45 1,000 0,02248198 0,12340944 ! regulation of protein complex disassembly GO:0043244 77 46 1,000 0,02342631 0,12828695 ! histone modification GO:0016570 68 46 1,000 0,02342631 0,12798223 ! viral infectious cycle GO:0019058 71 47 1,000 0,02438676 0,13291361 ! response to estrogen stimulus GO:0043627 74 47 1,000 0,02438676 0,13259939 ! covalent chromatin modification GO:0016569 75 47 1,000 0,02438676 0,13228666 ! regulation of neuron apoptosis GO:0043523 77 47 1,000 0,02438676 0,1319754 ! regulation of protein polymerization GO:0032271 71 47 1,000 0,02438676 0,13166559 ! positive regulation of caspase activity GO:0043280 72 48 1,000 0,02536313 0,13661639 GO:0010952|positive regulation of peptidase activity, ! cellular polysaccharide metabolic process GO:0044264 63 48 1,000 0,02536313 0,13629719 ! regulation of actin polymerization or depolymerization GO:0008064 68 48 1,000 0,02536313 0,13597948 ! regulation of interferon-alpha biosynthetic process GO:0045354 5 5 0,000 0,02547997 0,13628823 ! negative regulation of protein ubiquitination GO:0031397 7 5 0,000 0,02547997 0,13597202 ! positive regulation of G-protein coupled receptor protein signaling pathway GO:0045745 6 5 0,000 0,02547997 0,13565727 ! negative regulation of nucleotide biosynthetic process GO:0030809 7 5 0,000 0,02547997 0,13534397 GO:0030800|negative regulation of cyclic nucleotide metabolic process, GO:0030803|negative regulation of cyclic nucleotide biosynthetic process, ! autophagic vacuole formation GO:0000045 8 5 0,000 0,02547997 0,13503212 ! blood coagulation, extrinsic pathway GO:0007598 9 5 0,000 0,02547997 0,1347217 ! regulation of cGMP metabolic process GO:0030823 6 5 0,000 0,02547997 0,1344127 ! sleep GO:0030431 11 5 0,000 0,02547997 0,13410512 ! nucleotide-sugar transport GO:0015780 8 5 0,000 0,02547997 0,13379895 ! regulation of interferon-beta production GO:0032648 5 5 0,000 0,02547997 0,13349417 GO:0045359|positive regulation of interferon-beta biosynthetic process, GO:0045357|regulation of interferon-beta biosynthetic process, ! regulation of hormone biosynthetic process GO:0046885 7 5 0,000 0,02547997 0,13319077 ! forebrain regionalization GO:0021871 6 5 0,000 0,02547997 0,13288875 ! tongue development GO:0043586 6 5 0,000 0,02547997 0,1325881 ! DNA catabolic process, exonucleolytic GO:0000738 6 5 0,000 0,02547997 0,1322888 ! cell adhesion mediated by integrin GO:0033627 8 5 0,000 0,02547997 0,13199085 ! short-chain fatty acid metabolic process GO:0046459 7 5 0,000 0,02547997 0,13169424 ! cobalt ion transport GO:0006824 9 5 0,000 0,02547997 0,13139897 ! activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 10 5 0,000 0,02547997 0,13110501 ! SMAD protein complex assembly GO:0007183 9 5 0,000 0,02547997 0,13081236 ! regulation of respiratory gaseous exchange GO:0043576 7 5 0,000 0,02547997 0,13052102 ! protein thiol-disulfide exchange GO:0006467 5 5 0,000 0,02547997 0,13023097 ! receptor guanylyl cyclase signaling pathway GO:0007168 5 5 0,000 0,02547997 0,12994221 ! regulation of cardiac muscle cell proliferation GO:0060043 7 5 0,000 0,02547997 0,12965473 ! embryonic camera-type eye development GO:0031076 8 5 0,000 0,02547997 0,12936852 GO:0048596|embryonic camera-type eye morphogenesis, ! negative regulation of cell-cell adhesion GO:0022408 11 5 0,000 0,02547997 0,12908357 ! positive regulation of cell-cell adhesion GO:0022409 10 5 0,000 0,02547997 0,12879986 ! adaptation of signaling pathway GO:0022401 7 5 0,000 0,02547997 0,12851741 GO:0002029|desensitization of G-protein coupled receptor protein signaling pathway, ! regulation of collagen biosynthetic process GO:0032965 6 5 0,000 0,02547997 0,12823619 ! 2-oxoglutarate metabolic process GO:0006103 7 5 0,000 0,02547997 0,1279562 ! neurofilament cytoskeleton organization GO:0060052 8 5 0,000 0,02547997 0,12767743 ! positive regulation of histone modification GO:0031058 5 5 0,000 0,02547997 0,12739987 ! malate metabolic process GO:0006108 7 5 0,000 0,02547997 0,12712351 ! transcription from mitochondrial promoter GO:0006390 6 5 0,000 0,02547997 0,12684835 ! behavioral response to pain GO:0048266 7 5 0,000 0,02547997 0,12657438 ! clathrin coat assembly GO:0048268 11 5 0,000 0,02547997 0,12630159 ! phototransduction, visible light GO:0007603 6 5 0,000 0,02547997 0,12602998 ! regulation of dopamine uptake GO:0051584 9 5 0,000 0,02547997 0,12575952 GO:0051580|regulation of neurotransmitter uptake, GO:0051940|regulation of catecholamine uptake during transmission of nerve impulse, ! cerebral cortex radially oriented cell migration GO:0021799 8 5 0,000 0,02547997 0,12549023 ! mating behavior GO:0007617 6 5 0,000 0,02547997 0,12522209 ! metabotropic glutamate receptor signaling pathway GO:0007216 6 5 0,000 0,02547997 0,12495509 ! serotonin receptor signaling pathway GO:0007210 8 5 0,000 0,02547997 0,12468923 ! rhythmic behavior GO:0007622 12 5 0,000 0,02547997 0,1244245 ! copulation GO:0007620 7 5 0,000 0,02547997 0,12416089 ! glial cell fate commitment GO:0021781 12 5 0,000 0,02547997 0,12389839 ! protein maturation by protein folding GO:0022417 12 5 0,000 0,02547997 0,123637 ! embryonic hemopoiesis GO:0035162 10 5 0,000 0,02547997 0,12337671 ! regulation of potassium ion transport GO:0043266 9 5 0,000 0,02547997 0,12311752 ! regulation of smooth muscle cell differentiation GO:0051150 8 5 0,000 0,02547997 0,12285941 ! apoptotic cell clearance GO:0043277 13 5 0,000 0,02547997 0,12260238 ! lipoprotein particle clearance GO:0034381 9 5 0,000 0,02547997 0,12234643 ! fructose 1,6-bisphosphate metabolic process GO:0030388 6 5 0,000 0,02547997 0,12209154 ! leukocyte tethering or rolling GO:0050901 7 5 0,000 0,02547997 0,12183771 ! response to protozoan GO:0001562 9 5 0,000 0,02547997 0,12158493 ! positive regulation of glycolysis GO:0045821 11 5 0,000 0,02547997 0,12133321 ! lymph vessel development GO:0001945 7 5 0,000 0,02547997 0,12108252 ! endochondral ossification GO:0001958 12 5 0,000 0,02547997 0,12083286 GO:0060349|bone morphogenesis, GO:0060350|endochondral bone morphogenesis, ! positive regulation of neurotransmitter secretion GO:0001956 10 5 0,000 0,02547997 0,12058424 ! parathyroid gland development GO:0060017 8 5 0,000 0,02547997 0,12033663 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 8 5 0,000 0,02547997 0,12009004 ! anagen GO:0042640 6 5 0,000 0,02547997 0,11984446 ! positive regulation of viral genome replication GO:0045070 8 5 0,000 0,02547997 0,11959987 ! traversing start control point of mitotic cell cycle GO:0007089 11 5 0,000 0,02547997 0,11935629 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 11 5 0,000 0,02547997 0,1191137 GO:0045841|negative regulation of mitotic metaphase/anaphase transition, GO:0051784|negative regulation of nuclear division, ! nuclear migration GO:0007097 10 5 0,000 0,02547997 0,11887209 ! hydrogen peroxide biosynthetic process GO:0050665 6 5 0,000 0,02547997 0,11863145 ! dermatan sulfate proteoglycan biosynthetic process GO:0050651 7 5 0,000 0,02547997 0,1183918 GO:0050655|dermatan sulfate proteoglycan metabolic process, ! skeletal myofibril assembly GO:0014866 7 5 0,000 0,02547997 0,1181531 ! regulation of systemic arterial blood pressure by endothelin GO:0003100 6 5 0,000 0,02547997 0,11791537 ! peptidyl-lysine modification to hypusine GO:0008612 8 5 0,000 0,02547997 0,11767859 GO:0046516|hypusine metabolic process, ! cardiac muscle fiber development GO:0048739 7 5 0,000 0,02547997 0,11744276 ! regulation of retroviral genome replication GO:0045091 6 5 0,000 0,02547997 0,11720788 ! negative regulation of survival gene product expression GO:0008634 6 5 0,000 0,02547997 0,11697393 ! neutrophil mediated immunity GO:0002446 6 5 0,000 0,02547997 0,11674091 ! induction of apoptosis by oxidative stress GO:0008631 5 5 0,000 0,02547997 0,11650882 ! ovulation GO:0030728 6 5 0,000 0,02547997 0,11627766 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 7 5 0,000 0,02547997 0,1160474 GO:0033135|regulation of peptidyl-serine phosphorylation, ! microvillus organization GO:0032528 7 5 0,000 0,02547997 0,11581806 GO:0030033|microvillus assembly, ! valine metabolic process GO:0006573 8 5 0,000 0,02547997 0,11558962 ! response to pH GO:0009268 9 5 0,000 0,02547997 0,11536208 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 10 5 0,000 0,02547997 0,11513544 ! proline biosynthetic process GO:0006561 6 5 0,000 0,02547997 0,11490968 ! endoplasmic reticulum organization GO:0007029 11 5 0,000 0,02547997 0,11468481 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 15 5 0,000 0,02547997 0,11446082 ! positive regulation of interleukin-6 biosynthetic process GO:0045410 6 5 0,000 0,02547997 0,1142377 ! polyol catabolic process GO:0046174 7 5 0,000 0,02547997 0,11401544 GO:0019405|alditol catabolic process, ! polyol biosynthetic process GO:0046173 5 5 0,000 0,02547997 0,11379406 ! melanin biosynthetic process from tyrosine GO:0006583 6 5 0,000 0,02547997 0,11357352 ! regulation of cardiac muscle contraction GO:0055117 5 5 0,000 0,02547997 0,11335385 ! sister chromatid cohesion GO:0007062 9 5 0,000 0,02547997 0,11313502 ! nerve growth factor processing GO:0032455 7 5 0,000 0,02547997 0,11291703 ! urea metabolic process GO:0019627 6 5 0,000 0,02547997 0,11269988 GO:0043604|amide biosynthetic process, GO:0000050|urea cycle, ! response to ATP GO:0033198 6 5 0,000 0,02547997 0,11248357 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 7 5 0,000 0,02547997 0,11226808 ! regulation of retinoic acid receptor signaling pathway GO:0048385 11 5 0,000 0,02547997 0,11205342 ! neutrophil activation GO:0042119 5 5 0,000 0,02547997 0,11183958 ! regulation of angiotensin levels in blood GO:0002002 8 5 0,000 0,02547997 0,11162655 GO:0060177|regulation of angiotensin metabolic process, ! regulation of appetite GO:0032098 5 5 0,000 0,02547997 0,11141433 ! response to food GO:0032094 5 5 0,000 0,02547997 0,11120292 ! regulation of Cdc42 protein signal transduction GO:0032489 7 5 0,000 0,02547997 0,11099231 GO:0043088|regulation of Cdc42 GTPase activity, ! regulation of blood volume by renin-angiotensin GO:0002016 10 5 0,000 0,02547997 0,11078249 ! paraxial mesoderm development GO:0048339 9 5 0,000 0,02547997 0,11057347 ! forebrain neuron development GO:0021884 7 5 0,000 0,02547997 0,11036523 ! melanosome organization GO:0032438 7 5 0,000 0,02547997 0,11015778 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 6 5 0,000 0,02547997 0,1099511 ! substrate-bound cell migration, cell extension GO:0006930 5 5 0,000 0,02547997 0,1097452 ! positive regulation of neuroblast proliferation GO:0002052 8 5 0,000 0,02547997 0,10954007 ! cellular polysaccharide catabolic process GO:0044247 5 5 0,000 0,02547997 0,10933571 GO:0009251|glucan catabolic process, ! peptidyl-threonine phosphorylation GO:0018107 14 5 0,000 0,02547997 0,1091321 ! peptidyl-histidine phosphorylation GO:0018106 7 5 0,000 0,02547997 0,10892925 ! nucleoside transport GO:0015858 6 5 0,000 0,02547997 0,10872716 ! nucleoside salvage GO:0043174 7 5 0,000 0,02547997 0,10852581 GO:0006166|purine ribonucleoside salvage, ! attachment of GPI anchor to protein GO:0016255 9 5 0,000 0,02547997 0,10832521 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 6 5 0,000 0,02547997 0,10812535 GO:0002478|antigen processing and presentation of exogenous peptide antigen, GO:0019886|antigen processing and presentation of exogenous peptide antigen via MHC class II, ! folic acid transport GO:0015884 9 5 0,000 0,02547997 0,10792622 ! establishment of synaptic specificity at neuromuscular junction GO:0007529 6 5 0,000 0,02547997 0,10772783 ! positive regulation of vasoconstriction GO:0045907 9 5 0,000 0,02547997 0,10753016 ! depyrimidination GO:0045008 8 5 0,000 0,02547997 0,10733322 ! regulation of synaptic growth at neuromuscular junction GO:0008582 8 5 0,000 0,02547997 0,107137 ! 5S class rRNA transcription GO:0042791 8 5 0,000 0,02547997 0,10694149 GO:0042797|tRNA transcription from RNA polymerase III promoter, ! lipopolysaccharide biosynthetic process GO:0009103 5 5 0,000 0,02547997 0,1067467 ! regulation of centrosome cycle GO:0046605 7 5 0,000 0,02547997 0,10655262 ! neuronal ion channel clustering GO:0045161 7 5 0,000 0,02547997 0,10635924 ! sodium ion homeostasis GO:0055078 6 5 0,000 0,02547997 0,10616656 ! homeostasis of number of cells within a tissue GO:0048873 9 5 0,000 0,02547997 0,10597457 ! nucleoside monophosphate catabolic process GO:0009125 10 5 0,000 0,02547997 0,10578328 ! monocyte differentiation GO:0030224 8 5 0,000 0,02547997 0,10559268 ! negative regulation of peptide secretion GO:0002792 6 5 0,000 0,02547997 0,10540277 GO:0046676|negative regulation of insulin secretion, ! forebrain morphogenesis GO:0048853 13 5 0,000 0,02547997 0,10521353 ! leukemia inhibitory factor signaling pathway GO:0048861 8 5 0,000 0,02547997 0,10502498 ! negative regulation of alpha-beta T cell activation GO:0046636 6 5 0,000 0,02547997 0,1048371 GO:0046639|negative regulation of alpha-beta T cell differentiation, ! cardiac myofibril assembly GO:0055003 7 5 0,000 0,02547997 0,10464989 ! regulation of dendrite development GO:0050773 12 5 0,000 0,02547997 0,10446335 ! peptidyl-arginine modification GO:0018195 7 5 0,000 0,02547997 0,10427747 ! positive regulation of organ growth GO:0046622 6 5 0,000 0,02547997 0,10409225 ! negative regulation of T cell mediated immunity GO:0002710 11 5 0,000 0,02547997 0,10390769 GO:0002707|negative regulation of lymphocyte mediated immunity, ! melanosome transport GO:0032402 8 5 0,000 0,02547997 0,10372379 ! negative regulation of protein kinase B signaling cascade GO:0051898 11 5 0,000 0,02547997 0,10354053 ! regulation of dopamine secretion GO:0014059 12 5 0,000 0,02547997 0,10335792 ! respiratory chain complex IV assembly GO:0008535 9 5 0,000 0,02547997 0,10317595 ! CD4-positive, alpha beta T cell differentiation GO:0043367 7 5 0,000 0,02547997 0,10299462 ! purine deoxyribonucleotide catabolic process GO:0009155 5 5 0,000 0,02547997 0,10281393 ! regulation of interleukin-1 production GO:0032652 7 5 0,000 0,02547997 0,10263387 ! positive regulation of interleukin-4 production GO:0032753 8 5 0,000 0,02547997 0,10245444 GO:0032754|positive regulation of interleukin-5 production, ! base conversion or substitution editing GO:0016553 5 5 0,000 0,02547997 0,10227563 ! positive regulation of Rho GTPase activity GO:0032321 9 5 0,000 0,02547997 0,10209745 ! neural tube patterning GO:0021532 6 5 0,000 0,02547997 0,10191989 ! negative regulation of multicellular organism growth GO:0040015 7 5 0,000 0,02547997 0,10174295 ! histone demethylation GO:0016577 9 5 0,000 0,02547997 0,10156662 ! regulation of myeloid leukocyte mediated immunity GO:0002886 5 5 0,000 0,02547997 0,1013909 ! regulation of sterol transport GO:0032371 7 5 0,000 0,02547997 0,10121578 GO:0032374|regulation of cholesterol transport, ! positive regulation of chemokine production GO:0032722 7 5 0,000 0,02547997 0,10104127 ! enteric nervous system development GO:0048484 8 5 0,000 0,02547997 0,10086736 ! establishment of planar polarity GO:0001736 6 5 0,000 0,02547997 0,10069405 ! positive regulation of mast cell activation GO:0033005 5 5 0,000 0,02547997 0,10052134 ! muscle cell proliferation GO:0033002 8 5 0,000 0,02547997 0,10034921 ! transcription termination GO:0006353 8 5 0,000 0,02547997 0,10017767 ! negative regulation of peptidyl-tyrosine phosphorylation GO:0050732 13 5 0,000 0,02547997 0,10000672 ! positive regulation of pseudopodium assembly GO:0031274 13 5 0,000 0,02547997 0,09983635 GO:0031272|regulation of pseudopodium assembly, ! plasminogen activation GO:0031639 5 5 0,000 0,02547997 0,09966656 ! regulation of respiratory burst GO:0060263 8 5 0,000 0,02547997 0,09949735 ! positive regulation of blood coagulation GO:0030194 10 5 0,000 0,02547997 0,09932871 ! regulation of muscle cell apoptosis GO:0010660 8 5 0,000 0,02547997 0,09916064 ! energy coupled proton transport, against electrochemical gradient GO:0015988 6 5 0,000 0,02547997 0,09899314 GO:0015991|ATP hydrolysis coupled proton transport, ! regulation of hair follicle development GO:0051797 9 5 0,000 0,02547997 0,0988262 GO:0042634|regulation of hair cycle, ! protein destabilization GO:0031648 6 5 0,000 0,02547997 0,09865983 ! apical protein localization GO:0045176 6 5 0,000 0,02547997 0,09849401 ! negative regulation of osteoblast differentiation GO:0045668 5 5 0,000 0,02547997 0,09832876 ! tetrahydrobiopterin biosynthetic process GO:0006729 5 5 0,000 0,02547997 0,09816405 ! galactolipid metabolic process GO:0019374 7 5 0,000 0,02547997 0,0979999 GO:0006681|galactosylceramide metabolic process, ! porphyrin catabolic process GO:0006787 12 5 0,000 0,02547997 0,09783629 GO:0033015|tetrapyrrole catabolic process, ! nonprotein amino acid metabolic process GO:0019794 9 5 0,000 0,02547997 0,09767323 ! positive regulation of T cell mediated cytotoxicity GO:0001916 9 5 0,000 0,02547997 0,09751071 ! triglyceride catabolic process GO:0019433 6 5 0,000 0,02547997 0,09734874 ! glial cell migration GO:0008347 10 5 0,000 0,02547997 0,09718729 ! determination of adult lifespan GO:0008340 8 5 0,000 0,02547997 0,09702639 ! regulation of mitochondrial depolarization GO:0051900 9 5 0,000 0,02547997 0,09686601 ! ectodermal gut morphogenesis GO:0048567 5 5 0,000 0,02547997 0,09670617 GO:0007439|ectodermal gut development, ! lymphocyte activation during immune response GO:0002285 9 5 0,000 0,02547997 0,09654685 ! somatic stem cell maintenance GO:0035019 13 5 0,000 0,02547997 0,09638806 ! cerebellar cortex formation GO:0021697 6 5 0,000 0,02547997 0,09622978 ! neural plate development GO:0001840 6 5 0,000 0,02547997 0,09607203 ! regulation of sensory perception GO:0051931 6 5 0,000 0,02547997 0,09591479 GO:0051930|regulation of sensory perception of pain, ! negative regulation of NF-kappaB import into nucleus GO:0042347 9 5 0,000 0,02547997 0,09575807 ! regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0032239 9 5 0,000 0,02547997 0,09560186 GO:0046831|regulation of RNA export from nucleus, ! hemopoietic progenitor cell differentiation GO:0002244 10 5 0,000 0,02547997 0,09544615 ! positive regulation of actin filament bundle formation GO:0032233 12 5 0,000 0,02547997 0,09529096 ! sensory cilium assembly GO:0035058 6 5 0,000 0,02547997 0,09513626 ! activation of phospholipase C activity by dopamine receptor signaling pathway GO:0060158 13 5 0,000 0,02547997 0,09498207 ! release of sequestered calcium ion into cytosol GO:0051209 11 5 0,000 0,02547997 0,09482838 GO:0051282|regulation of sequestering of calcium ion, GO:0051283|negative regulation of sequestering of calcium ion, GO:0060401|cytosolic calcium ion transport, GO:0060402|calcium ion transport into cytosol, ! negative regulation of smooth muscle contraction GO:0045986 9 5 0,000 0,02547997 0,09467518 ! spindle assembly GO:0051225 5 5 0,000 0,02547997 0,09452248 ! ensheathment of axons in the peripheral nervous system GO:0032292 13 5 0,000 0,02547997 0,09437027 GO:0022011|myelination in the peripheral nervous system, ! receptor biosynthetic process GO:0032800 6 5 0,000 0,02547997 0,09421855 ! protein amino acid prenylation GO:0018346 9 5 0,000 0,02547997 0,09406732 ! organ regeneration GO:0031100 7 5 0,000 0,02547997 0,09391657 ! carnitine metabolic process GO:0009437 5 5 0,000 0,02547997 0,0937663 GO:0006577|betaine metabolic process, ! positive regulation of microtubule polymerization GO:0031116 9 5 0,000 0,02547997 0,09361652 ! cellular anion homeostasis GO:0030002 6 5 0,000 0,02547997 0,09346721 GO:0055081|anion homeostasis, ! morphogenesis of a branching structure GO:0001763 86 49 1,000 0,02635524 0,09652398 ! germ cell development GO:0007281 68 49 1,000 0,02635524 0,09637052 ! heterocycle catabolic process GO:0046700 72 49 1,000 0,02635524 0,09621755 ! maintenance of location GO:0051235 84 49 1,000 0,02635524 0,09606507 ! regulation of actin filament length GO:0030832 72 50 1,000 0,02736291 0,09958021 ! membrane fusion GO:0006944 80 50 1,000 0,02736291 0,0994229 ! negative regulation of cytoskeleton organization GO:0051494 84 50 1,000 0,02736291 0,09926608 ! lipid modification GO:0030258 73 50 1,000 0,02736291 0,09910976 ! regulation of cellular component size GO:0032535 74 52 1,000 0,02942419 0,10640823 ! regulation of bone remodeling GO:0046850 90 53 1,000 0,03047744 0,11004413 ! skeletal system morphogenesis GO:0048705 78 53 1,000 0,03047744 0,10987164 ! tRNA transcription GO:0009304 11 6 0,000 0,03049839 0,1097751 ! positive regulation of MHC class II biosynthetic process GO:0045348 8 6 0,000 0,03049839 0,10960358 GO:0045346|regulation of MHC class II biosynthetic process, ! positive regulation of protein ubiquitination GO:0031398 8 6 0,000 0,03049839 0,10943259 ! negative regulation of S phase of mitotic cell cycle GO:0045749 7 6 0,000 0,03049839 0,10926213 ! positive regulation of cAMP biosynthetic process GO:0030819 11 6 0,000 0,03049839 0,10909221 GO:0030816|positive regulation of cAMP metabolic process, ! positive regulation of DNA repair GO:0045739 7 6 0,000 0,03049839 0,10892281 ! oligosaccharide biosynthetic process GO:0009312 8 6 0,000 0,03049839 0,10875394 ! regulation of tumor necrosis factor biosynthetic process GO:0042534 8 6 0,000 0,03049839 0,10858559 ! chaperone mediated protein folding requiring cofactor GO:0051085 7 6 0,000 0,03049839 0,10841776 ! positive regulation of axon extension GO:0045773 8 6 0,000 0,03049839 0,10825044 ! prostate gland development GO:0030850 9 6 0,000 0,03049839 0,10808365 ! negative regulation of small GTPase mediated signal transduction GO:0051058 10 6 0,000 0,03049839 0,10791737 GO:0046580|negative regulation of Ras protein signal transduction, ! virion attachment to host cell surface receptor GO:0019062 11 6 0,000 0,03049839 0,10775159 ! forebrain neuron differentiation GO:0021879 9 6 0,000 0,03049839 0,10758633 GO:0021872|generation of neurons in the forebrain, ! regulation of lipid catabolic process GO:0050994 9 6 0,000 0,03049839 0,10742157 ! neutral lipid biosynthetic process GO:0046460 8 6 0,000 0,03049839 0,10725732 GO:0046463|acylglycerol biosynthetic process, ! meiotic prophase I GO:0007128 9 6 0,000 0,03049839 0,10709357 ! N-acetylglucosamine catabolic process GO:0006046 8 6 0,000 0,03049839 0,10693032 GO:0006032|chitin catabolic process, GO:0006030|chitin metabolic process, ! transmembrane receptor protein tyrosine phosphatase signaling pathway GO:0007185 17 6 0,000 0,03049839 0,10676756 ! neuron adhesion GO:0007158 9 6 0,000 0,03049839 0,1066053 ! establishment of tissue polarity GO:0007164 7 6 0,000 0,03049839 0,10644353 ! nucleotide-excision repair, DNA incision GO:0033683 7 6 0,000 0,03049839 0,10628225 ! signal peptide processing GO:0006465 8 6 0,000 0,03049839 0,10612146 ! mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 6 6 0,000 0,03049839 0,10596116 ! glucocorticoid receptor signaling pathway GO:0042921 9 6 0,000 0,03049839 0,10580134 GO:0031958|corticosteroid receptor signaling pathway, ! posttranscriptional gene silencing by RNA GO:0035194 12 6 0,000 0,03049839 0,105642 GO:0016441|posttranscriptional gene silencing, ! protein refolding GO:0042026 13 6 0,000 0,03049839 0,10548314 ! opsonization GO:0008228 8 6 0,000 0,03049839 0,10532476 ! regulation of dopamine metabolic process GO:0042053 9 6 0,000 0,03049839 0,10516685 GO:0042069|regulation of catecholamine metabolic process, ! erythrocyte maturation GO:0043249 6 6 0,000 0,03049839 0,10500941 ! sensory perception of temperature stimulus GO:0050951 10 6 0,000 0,03049839 0,10485245 ! protein amino acid dealkylation GO:0008214 11 6 0,000 0,03049839 0,10469595 GO:0006482|protein amino acid demethylation, ! glucocorticoid metabolic process GO:0008211 7 6 0,000 0,03049839 0,10453992 ! photoreceptor cell development GO:0042461 10 6 0,000 0,03049839 0,10438436 GO:0046530|photoreceptor cell differentiation, ! regulation of odontogenesis GO:0042481 8 6 0,000 0,03049839 0,10422925 ! amyloid precursor protein catabolic process GO:0042987 9 6 0,000 0,03049839 0,10407461 ! mechanosensory behavior GO:0007638 8 6 0,000 0,03049839 0,10392043 ! DNA ligation during DNA repair GO:0051103 9 6 0,000 0,03049839 0,1037667 ! negative regulation of endocytosis GO:0045806 8 6 0,000 0,03049839 0,10361342 ! positive regulation of gene expression, epigenetic GO:0045815 12 6 0,000 0,03049839 0,1034606 ! regulation of interleukin-12 biosynthetic process GO:0045075 6 6 0,000 0,03049839 0,10330823 ! negative regulation of viral genome replication GO:0045071 7 6 0,000 0,03049839 0,10315631 ! lipopolysaccharide metabolic process GO:0008653 6 6 0,000 0,03049839 0,10300483 ! spinal cord dorsal/ventral patterning GO:0021513 6 6 0,000 0,03049839 0,1028538 ! cGMP-mediated signaling GO:0019934 10 6 0,000 0,03049839 0,1027032 ! activation of MAPKKK activity GO:0000185 10 6 0,000 0,03049839 0,10255305 ! inositol phosphate-mediated signaling GO:0048016 9 6 0,000 0,03049839 0,10240334 ! thymic T cell selection GO:0045061 12 6 0,000 0,03049839 0,10225406 ! protein lipoylation GO:0009249 10 6 0,000 0,03049839 0,10210522 ! regulation of transcriptional preinitiation complex assembly GO:0045898 8 6 0,000 0,03049839 0,10195681 ! pigment granule organization GO:0048753 11 6 0,000 0,03049839 0,10180884 ! drug transport GO:0015893 6 6 0,000 0,03049839 0,10166129 ! cysteine metabolic process GO:0006534 7 6 0,000 0,03049839 0,10151417 ! regulation of defense response to virus by host GO:0050691 6 6 0,000 0,03049839 0,10136747 ! regulation of isotype switching to IgG isotypes GO:0048302 9 6 0,000 0,03049839 0,1012212 ! histidine metabolic process GO:0006547 6 6 0,000 0,03049839 0,10107534 GO:0009075|histidine family amino acid metabolic process, ! glutamate catabolic process GO:0006538 10 6 0,000 0,03049839 0,10092991 ! mitochondrial respiratory chain complex assembly GO:0033108 8 6 0,000 0,03049839 0,1007849 GO:0010257|NADH dehydrogenase complex assembly, GO:0032981|mitochondrial respiratory chain complex I assembly, ! cell fate commitment involved in the formation of primary germ layers GO:0060795 8 6 0,000 0,03049839 0,1006403 GO:0048333|mesodermal cell differentiation, GO:0001710|mesodermal cell fate commitment, ! glycine catabolic process GO:0006546 9 6 0,000 0,03049839 0,10049611 ! adenohypophysis development GO:0021984 10 6 0,000 0,03049839 0,10035234 ! deoxyribonucleotide biosynthetic process GO:0009263 8 6 0,000 0,03049839 0,10020898 ! hyperosmotic response GO:0006972 8 6 0,000 0,03049839 0,10006603 ! microtubule nucleation GO:0007020 10 6 0,000 0,03049839 0,09992349 ! regulation of interleukin-6 biosynthetic process GO:0045408 7 6 0,000 0,03049839 0,09978135 ! positive regulation of interleukin-8 biosynthetic process GO:0045416 7 6 0,000 0,03049839 0,09963961 ! tetrahydrobiopterin metabolic process GO:0046146 6 6 0,000 0,03049839 0,09949828 ! vascular smooth muscle contraction GO:0014829 10 6 0,000 0,03049839 0,09935735 ! positive regulation of muscle hypertrophy GO:0014742 9 6 0,000 0,03049839 0,09921682 GO:0014744|positive regulation of muscle adaptation, GO:0010615|positive regulation of cardiac muscle adaptation, GO:0010613|positive regulation of cardiac muscle hypertrophy, ! negative regulation of NF-kappaB transcription factor activity GO:0032088 13 6 0,000 0,03049839 0,09907668 ! response to dietary excess GO:0002021 7 6 0,000 0,03049839 0,09893694 ! positive regulation of insulin secretion GO:0032024 8 6 0,000 0,03049839 0,09879759 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 9 6 0,000 0,03049839 0,09865863 ! maintenance of protein location in nucleus GO:0051457 16 6 0,000 0,03049839 0,09852007 ! glycerol ether catabolic process GO:0044269 8 6 0,000 0,03049839 0,09838189 GO:0046464|acylglycerol catabolic process, ! purine salvage GO:0043101 8 6 0,000 0,03049839 0,0982441 ! positive regulation of multicellular organismal metabolic process GO:0044253 7 6 0,000 0,03049839 0,0981067 ! neuron apoptosis GO:0051402 8 6 0,000 0,03049839 0,09796968 ! organic alcohol transport GO:0015850 9 6 0,000 0,03049839 0,09783304 ! positive regulation of nitric-oxide synthase activity GO:0051000 10 6 0,000 0,03049839 0,09769678 ! T cell mediated immunity GO:0002456 12 6 0,000 0,03049839 0,0975609 ! male sex determination GO:0030238 9 6 0,000 0,03049839 0,0974254 ! carnitine transport GO:0015879 8 6 0,000 0,03049839 0,09729027 GO:0015838|betaine transport, ! antigen processing and presentation of endogenous peptide antigen GO:0002483 12 6 0,000 0,03049839 0,09715552 GO:0019885|antigen processing and presentation of endogenous peptide antigen via MHC class I, GO:0019883|antigen processing and presentation of endogenous antigen, ! macroautophagy GO:0016236 10 6 0,000 0,03049839 0,09702115 ! regulation of immunoglobulin secretion GO:0051023 6 6 0,000 0,03049839 0,09688714 ! negative regulation of DNA recombination GO:0045910 9 6 0,000 0,03049839 0,0967535 ! positive regulation of exocytosis GO:0045921 6 6 0,000 0,03049839 0,09662023 ! protein import into mitochondrial inner membrane GO:0045039 6 6 0,000 0,03049839 0,09648733 ! parturition GO:0007567 12 6 0,000 0,03049839 0,09635479 ! negative regulation of translational initiation GO:0045947 7 6 0,000 0,03049839 0,09622262 ! regulation of chromatin assembly or disassembly GO:0001672 11 6 0,000 0,03049839 0,09609081 ! protein ubiquitination during ubiquitin-dependent protein catabolic process GO:0042787 11 6 0,000 0,03049839 0,09595935 ! spindle checkpoint GO:0031577 14 6 0,000 0,03049839 0,09582826 ! regulation of collagen metabolic process GO:0010712 7 6 0,000 0,03049839 0,09569753 ! wound healing, spreading of epidermal cells GO:0035313 10 6 0,000 0,03049839 0,09556715 ! regulation of cholesterol biosynthetic process GO:0045540 6 6 0,000 0,03049839 0,09543713 ! deoxyribonucleoside metabolic process GO:0009120 7 6 0,000 0,03049839 0,09530746 ! macrophage differentiation GO:0030225 10 6 0,000 0,03049839 0,09517814 ! astrocyte development GO:0014002 14 6 0,000 0,03049839 0,09504917 ! hyaluronan metabolic process GO:0030212 6 6 0,000 0,03049839 0,09492055 ! purine base biosynthetic process GO:0009113 14 6 0,000 0,03049839 0,09479228 ! interaction with symbiont GO:0051702 8 6 0,000 0,03049839 0,09466436 ! anterograde axon cargo transport GO:0008089 8 6 0,000 0,03049839 0,09453678 ! skeletal muscle contraction GO:0003009 6 6 0,000 0,03049839 0,09440954 ! eating behavior GO:0042755 6 6 0,000 0,03049839 0,09428265 ! positive regulation of cytokine production during immune response GO:0002720 8 6 0,000 0,03049839 0,09415609 ! transcription-coupled nucleotide-excision repair GO:0006283 6 6 0,000 0,03049839 0,09402988 ! response to copper ion GO:0046688 9 6 0,000 0,03049839 0,093904 ! DNA topological change GO:0006265 8 6 0,000 0,03049839 0,09377846 ! response to exogenous dsRNA GO:0043330 8 6 0,000 0,03049839 0,09365326 ! enucleate erythrocyte differentiation GO:0043353 9 6 0,000 0,03049839 0,09352838 ! establishment of melanosome localization GO:0032401 9 6 0,000 0,03049839 0,09340385 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 9 6 0,000 0,03049839 0,09327964 ! regulation of interleukin-5 production GO:0032674 9 6 0,000 0,03049839 0,09315576 ! positive regulation of B cell differentiation GO:0045579 9 6 0,000 0,03049839 0,09303221 ! negative regulation of focal adhesion formation GO:0051895 16 6 0,000 0,03049839 0,09290899 ! nucleoside catabolic process GO:0009164 6 6 0,000 0,03049839 0,0927861 ! gas homeostasis GO:0033483 11 6 0,000 0,03049839 0,09266352 ! hair follicle maturation GO:0048820 7 6 0,000 0,03049839 0,09254128 ! negative regulation of T cell differentiation GO:0045581 7 6 0,000 0,03049839 0,09241935 ! phosphatidylinositol biosynthetic process GO:0006661 10 6 0,000 0,03049839 0,09229775 ! Schwann cell development GO:0014044 14 6 0,000 0,03049839 0,09217646 ! purine deoxyribonucleotide metabolic process GO:0009151 6 6 0,000 0,03049839 0,0920555 ! dendrite morphogenesis GO:0048813 9 6 0,000 0,03049839 0,09193485 ! regulation of interleukin-13 production GO:0032656 11 6 0,000 0,03049839 0,09181451 ! phosphatidylserine metabolic process GO:0006658 6 6 0,000 0,03049839 0,09169449 ! regulation of myeloid cell apoptosis GO:0033032 10 6 0,000 0,03049839 0,09157479 ! cell differentiation in hindbrain GO:0021533 8 6 0,000 0,03049839 0,0914554 ! histone ubiquitination GO:0016574 7 6 0,000 0,03049839 0,09133631 ! regulation of meiosis GO:0040020 10 6 0,000 0,03049839 0,09121754 GO:0051445|regulation of meiotic cell cycle, ! G2 phase GO:0051319 13 6 0,000 0,03049839 0,09109908 GO:0000085|G2 phase of mitotic cell cycle, ! establishment of chromosome localization GO:0051303 9 6 0,000 0,03049839 0,09098092 GO:0050000|chromosome localization, ! regulation of cell division GO:0051302 8 6 0,000 0,03049839 0,09086307 ! regulation of mast cell activation GO:0033003 6 6 0,000 0,03049839 0,09074552 ! membrane to membrane docking GO:0022614 12 6 0,000 0,03049839 0,09062828 ! positive regulation of natural killer cell mediated immune response to tumor cell GO:0002857 8 6 0,000 0,03049839 0,09051134 GO:0002858|regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, GO:0002855|regulation of natural killer cell mediated immune response to tumor cell, GO:0002860|positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target, ! regulation of inflammatory response to antigenic stimulus GO:0002861 7 6 0,000 0,03049839 0,0903947 ! negative regulation of oxidoreductase activity GO:0051354 10 6 0,000 0,03049839 0,09027836 ! receptor internalization GO:0031623 9 6 0,000 0,03049839 0,09016232 ! neutrophil homeostasis GO:0001780 6 6 0,000 0,03049839 0,09004658 ! coenzyme A metabolic process GO:0015936 9 6 0,000 0,03049839 0,08993114 ! myeloid dendritic cell activation GO:0001773 10 6 0,000 0,03049839 0,08981599 GO:0043011|myeloid dendritic cell differentiation, ! salivary gland morphogenesis GO:0007435 11 6 0,000 0,03049839 0,08970114 ! protein deubiquitination GO:0016579 8 6 0,000 0,03049839 0,08958657 GO:0070646|protein modification by small protein removal, ! regulation of macrophage activation GO:0043030 11 6 0,000 0,03049839 0,08947231 ! peptidyl-histidine modification GO:0018202 9 6 0,000 0,03049839 0,08935833 ! regulation of myoblast differentiation GO:0045661 8 6 0,000 0,03049839 0,08924464 ! thiamin metabolic process GO:0006772 6 6 0,000 0,03049839 0,08913124 ! midbrain development GO:0030901 6 6 0,000 0,03049839 0,08901813 ! regulation of epidermal cell differentiation GO:0045604 7 6 0,000 0,03049839 0,08890531 ! regulation of viral transcription GO:0046782 8 6 0,000 0,03049839 0,08879277 ! progesterone metabolic process GO:0042448 8 6 0,000 0,03049839 0,08868052 ! aspartate family amino acid catabolic process GO:0009068 7 6 0,000 0,03049839 0,08856855 ! glycolipid catabolic process GO:0019377 13 6 0,000 0,03049839 0,08845686 GO:0046479|glycosphingolipid catabolic process, ! positive regulation of glucose import GO:0046326 6 6 0,000 0,03049839 0,08834545 GO:0010828|positive regulation of glucose transport, ! removal of superoxide radicals GO:0019430 10 6 0,000 0,03049839 0,08823432 ! adult feeding behavior GO:0008343 6 6 0,000 0,03049839 0,08812348 ! regulation of Rac protein signal transduction GO:0035020 8 6 0,000 0,03049839 0,08801291 ! pigment granule transport GO:0051904 12 6 0,000 0,03049839 0,08790262 ! positive regulation of fibrinolysis GO:0051919 7 6 0,000 0,03049839 0,0877926 ! regulation of synaptic transmission, dopaminergic GO:0032225 10 6 0,000 0,03049839 0,08768286 ! catecholamine transport GO:0051937 7 6 0,000 0,03049839 0,08757339 ! organ or tissue specific immune response GO:0002251 7 6 0,000 0,03049839 0,0874642 ! regulation of T cell receptor signaling pathway GO:0050856 8 6 0,000 0,03049839 0,08735528 ! positive regulation of smooth muscle contraction GO:0045987 9 6 0,000 0,03049839 0,08724663 ! negative regulation of B cell activation GO:0050869 9 6 0,000 0,03049839 0,08713825 ! protein prenylation GO:0018342 10 6 0,000 0,03049839 0,08703013 ! negative regulation of synaptic transmission GO:0050805 13 6 0,000 0,03049839 0,08692229 ! positive regulation of microtubule polymerization or depolymerization GO:0031112 11 6 0,000 0,03049839 0,08681471 ! regulation of microtubule polymerization GO:0031113 11 6 0,000 0,03049839 0,0867074 ! positive regulation of coagulation GO:0050820 11 6 0,000 0,03049839 0,08660036 ! regulation of protein complex assembly GO:0043254 81 54 1,000 0,03154552 0,08946325 ! cytokine-mediated signaling pathway GO:0019221 76 54 1,000 0,03154552 0,08935308 ! regulation of tissue remodeling GO:0034103 91 54 1,000 0,03154552 0,08924317 ! cellular amino acid catabolic process GO:0009063 74 54 1,000 0,03154552 0,08913354 ! mesoderm development GO:0007498 76 55 1,000 0,03262826 0,09207976 ! water-soluble vitamin metabolic process GO:0006767 71 55 1,000 0,03262826 0,09196692 ! negative regulation of protein kinase activity GO:0006469 99 57 1,000 0,03483702 0,09807238 ! coenzyme biosynthetic process GO:0009108 67 57 1,000 0,03483702 0,09795249 ! secondary metabolic process GO:0019748 84 57 1,000 0,03483702 0,09783289 ! response to peptide hormone stimulus GO:0043434 84 57 1,000 0,03483702 0,09771358 ! developmental maturation GO:0021700 75 57 1,000 0,03483702 0,09759456 ! gonad development GO:0008406 79 57 1,000 0,03483702 0,09747584 ! positive regulation of cyclin-dependent protein kinase activity GO:0045737 18 7 0,000 0,03549124 0,09918573 ! somatic diversification of immune receptors via somatic mutation GO:0002566 9 7 0,000 0,03549124 0,09906536 GO:0016446|somatic hypermutation of immunoglobulin genes, ! positive regulation of membrane protein ectodomain proteolysis GO:0051044 9 7 0,000 0,03549124 0,09894528 ! negative regulation of cellular catabolic process GO:0031330 9 7 0,000 0,03549124 0,09882549 ! negative regulation of lipid biosynthetic process GO:0051055 9 7 0,000 0,03549124 0,09870599 ! regulation of interferon-alpha production GO:0032647 7 7 0,000 0,03549124 0,09858678 ! synaptonemal complex assembly GO:0007130 10 7 0,000 0,03549124 0,09846786 GO:0070193|synaptonemal complex organization, ! glycerol-3-phosphate metabolic process GO:0006072 9 7 0,000 0,03549124 0,09834922 ! negative regulation of transmembrane transport GO:0034763 7 7 0,000 0,03549124 0,09823087 GO:0044070|regulation of anion transport, GO:0002036|regulation of L-glutamate transport, GO:0002037|negative regulation of L-glutamate transport, GO:0051953|negative regulation of amine transport, GO:0051956|negative regulation of amino acid transport, ! neutral lipid catabolic process GO:0046461 9 7 0,000 0,03549124 0,09811281 ! regulation of cellular amine metabolic process GO:0033238 10 7 0,000 0,03549124 0,09799503 ! reproductive behavior GO:0019098 12 7 0,000 0,03549124 0,09787753 ! cellular copper ion homeostasis GO:0006878 9 7 0,000 0,03549124 0,09776031 ! regulation of lipid kinase activity GO:0043550 12 7 0,000 0,03549124 0,09764337 ! carbohydrate phosphorylation GO:0046835 8 7 0,000 0,03549124 0,09752671 ! regulation of smooth muscle cell migration GO:0014910 19 7 0,000 0,03549124 0,09741033 ! oligopeptide transport GO:0006857 11 7 0,000 0,03549124 0,09729423 ! protein amino acid sulfation GO:0006477 9 7 0,000 0,03549124 0,0971784 GO:0051923|sulfation, ! actin-myosin filament sliding GO:0033275 10 7 0,000 0,03549124 0,09706285 GO:0070252|actin-mediated cell contraction, GO:0030049|muscle filament sliding, ! negative regulation of JAK-STAT cascade GO:0046426 15 7 0,000 0,03549124 0,09694757 ! RNA methylation GO:0001510 11 7 0,000 0,03549124 0,09683257 ! pericardium development GO:0060039 8 7 0,000 0,03549124 0,09671784 ! macrophage chemotaxis GO:0048246 10 7 0,000 0,03549124 0,09660338 ! fibril organization GO:0043206 13 7 0,000 0,03549124 0,09648919 ! oxaloacetate metabolic process GO:0006107 9 7 0,000 0,03549124 0,09637527 ! regulation of gluconeogenesis GO:0006111 7 7 0,000 0,03549124 0,09626162 ! detection of mechanical stimulus involved in sensory perception of sound GO:0050910 9 7 0,000 0,03549124 0,09614824 ! positive regulation of neurotransmitter transport GO:0051590 15 7 0,000 0,03549124 0,09603512 ! lipoprotein transport GO:0042953 9 7 0,000 0,03549124 0,09592228 ! cerebral cortex cell migration GO:0021795 11 7 0,000 0,03549124 0,09580969 ! tachykinin receptor signaling pathway GO:0007217 11 7 0,000 0,03549124 0,09569737 ! regulation of inhibitory postsynaptic membrane potential GO:0060080 9 7 0,000 0,03549124 0,09558531 ! estrogen metabolic process GO:0008210 14 7 0,000 0,03549124 0,09547352 ! regulation of systemic arterial blood pressure by circulatory renin-angiotensin GO:0001991 13 7 0,000 0,03549124 0,09536198 ! negative regulation of muscle cell differentiation GO:0051148 9 7 0,000 0,03549124 0,09525071 ! chemosensory behavior GO:0007635 9 7 0,000 0,03549124 0,09513969 ! microtubule bundle formation GO:0001578 8 7 0,000 0,03549124 0,09502894 ! regulation of response to extracellular stimulus GO:0032104 10 7 0,000 0,03549124 0,09491844 GO:0032107|regulation of response to nutrient levels, ! synaptic transmission, dopaminergic GO:0001963 11 7 0,000 0,03549124 0,0948082 ! leukocyte degranulation GO:0043299 10 7 0,000 0,03549124 0,09469821 ! bile acid and bile salt transport GO:0015721 9 7 0,000 0,03549124 0,09458848 ! reflex GO:0060004 12 7 0,000 0,03549124 0,094479 ! positive regulation of isotype switching GO:0045830 15 7 0,000 0,03549124 0,09436978 GO:0045911|positive regulation of DNA recombination, ! positive regulation of heart rate GO:0010460 9 7 0,000 0,03549124 0,0942608 ! protein-cofactor linkage GO:0018065 13 7 0,000 0,03549124 0,09415208 ! glycerol ether biosynthetic process GO:0046504 10 7 0,000 0,03549124 0,09404361 ! glycerolipid catabolic process GO:0046503 9 7 0,000 0,03549124 0,09393539 ! positive regulation of chemokine biosynthetic process GO:0045080 8 7 0,000 0,03549124 0,09382742 ! spinal cord patterning GO:0021511 7 7 0,000 0,03549124 0,0937197 ! hemoglobin metabolic process GO:0020027 10 7 0,000 0,03549124 0,09361222 ! adrenal gland development GO:0030325 17 7 0,000 0,03549124 0,09350499 ! pyrimidine deoxyribonucleotide catabolic process GO:0009223 10 7 0,000 0,03549124 0,093398 ! regulation of defense response to virus by virus GO:0050690 16 7 0,000 0,03549124 0,09329126 ! outer mitochondrial membrane organization GO:0007008 12 7 0,000 0,03549124 0,09318477 GO:0070096|mitochondrial outer membrane translocase complex assembly, ! nucleobase, nucleoside and nucleotide catabolic process GO:0034656 7 7 0,000 0,03549124 0,09307851 GO:0034655|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process, ! proline metabolic process GO:0006560 8 7 0,000 0,03549124 0,0929725 ! endosome organization GO:0007032 10 7 0,000 0,03549124 0,09286673 ! thyroid hormone generation GO:0006590 11 7 0,000 0,03549124 0,0927612 ! regulation of granule cell precursor proliferation GO:0021936 11 7 0,000 0,03549124 0,09265591 GO:0021940|positive regulation of granule cell precursor proliferation, ! regulation of interleukin-8 biosynthetic process GO:0045414 9 7 0,000 0,03549124 0,09255086 ! regulation of pigmentation during development GO:0048070 15 7 0,000 0,03549124 0,09244604 ! phasic smooth muscle contraction GO:0014821 12 7 0,000 0,03549124 0,09234147 ! central nervous system neuron axonogenesis GO:0021955 14 7 0,000 0,03549124 0,09223713 GO:0021952|central nervous system projection neuron axonogenesis, ! positive regulation of activated T cell proliferation GO:0042104 12 7 0,000 0,03549124 0,09213302 ! galactose metabolic process GO:0006012 10 7 0,000 0,03549124 0,09202915 ! vesicle fusion GO:0006906 15 7 0,000 0,03549124 0,09192551 ! intracellular pH reduction GO:0051452 10 7 0,000 0,03549124 0,09182211 GO:0045851|pH reduction, ! asymmetric protein localization GO:0008105 8 7 0,000 0,03549124 0,09171894 ! organ growth GO:0035265 11 7 0,000 0,03549124 0,091616 ! synaptic transmission, glutamatergic GO:0035249 13 7 0,000 0,03549124 0,09151329 ! positive regulation of mesenchymal cell proliferation GO:0002053 9 7 0,000 0,03549124 0,09141081 ! Rac protein signal transduction GO:0016601 7 7 0,000 0,03549124 0,09130856 ! retinol metabolic process GO:0042572 9 7 0,000 0,03549124 0,09120654 ! behavioral fear response GO:0001662 13 7 0,000 0,03549124 0,09110475 GO:0002209|behavioral defense response, ! negative regulation of muscle contraction GO:0045932 12 7 0,000 0,03549124 0,09100318 ! rRNA modification GO:0000154 12 7 0,000 0,03549124 0,09090184 ! protein heterooligomerization GO:0051291 10 7 0,000 0,03549124 0,09080073 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 13 7 0,000 0,03549124 0,09069984 ! response to UV-B GO:0010224 11 7 0,000 0,03549124 0,09059917 ! protein retention in ER lumen GO:0006621 12 7 0,000 0,03549124 0,09049873 ! intermediate filament organization GO:0045109 11 7 0,000 0,03549124 0,09039851 ! cardiac muscle cell differentiation GO:0055007 12 7 0,000 0,03549124 0,09029851 ! cardiac muscle cell development GO:0055013 9 7 0,000 0,03549124 0,09019874 ! fibrinolysis GO:0042730 9 7 0,000 0,03549124 0,09009918 ! negative regulation of insulin receptor signaling pathway GO:0046627 11 7 0,000 0,03549124 0,08999984 ! regulation of circadian rhythm GO:0042752 11 7 0,000 0,03549124 0,08990072 ! antigen processing and presentation of exogenous antigen GO:0019884 9 7 0,000 0,03549124 0,08980182 ! positive regulation of production of molecular mediator of immune response GO:0002702 9 7 0,000 0,03549124 0,08970314 ! response to tropane GO:0014073 13 7 0,000 0,03549124 0,08960467 GO:0042220|response to cocaine, GO:0048148|behavioral response to cocaine, ! regulation of fat cell differentiation GO:0045598 9 7 0,000 0,03549124 0,08950642 ! melanosome localization GO:0032400 10 7 0,000 0,03549124 0,08940839 ! positive regulation of systemic arterial blood pressure GO:0003084 9 7 0,000 0,03549124 0,08931056 ! negative regulation of interferon-gamma production GO:0032689 11 7 0,000 0,03549124 0,08921296 ! negative regulation of systemic arterial blood pressure GO:0003085 15 7 0,000 0,03549124 0,08911556 ! sphingomyelin metabolic process GO:0006684 8 7 0,000 0,03549124 0,08901838 ! nucleoside diphosphate metabolic process GO:0009132 8 7 0,000 0,03549124 0,08892141 ! glycosylceramide metabolic process GO:0006677 9 7 0,000 0,03549124 0,08882465 ! mast cell activation GO:0045576 9 7 0,000 0,03549124 0,0887281 ! multicellular organismal aging GO:0010259 11 7 0,000 0,03549124 0,08863177 ! regulation of focal adhesion formation GO:0051893 17 7 0,000 0,03549124 0,08853564 ! regulation of interleukin-10 production GO:0032653 11 7 0,000 0,03549124 0,08843971 ! positive regulation of tumor necrosis factor production GO:0032760 8 7 0,000 0,03549124 0,088344 ! positive regulation of monooxygenase activity GO:0032770 11 7 0,000 0,03549124 0,08824849 ! spinal cord motor neuron differentiation GO:0021522 9 7 0,000 0,03549124 0,08815319 ! establishment of nucleus localization GO:0040023 13 7 0,000 0,03549124 0,0880581 ! transcription from RNA polymerase I promoter GO:0006360 12 7 0,000 0,03549124 0,08796321 ! positive regulation of immunoglobulin mediated immune response GO:0002891 9 7 0,000 0,03549124 0,08786852 GO:0002714|positive regulation of B cell mediated immunity, ! synaptic vesicle endocytosis GO:0048488 16 7 0,000 0,03549124 0,08777404 ! mitochondrion morphogenesis GO:0070584 11 7 0,000 0,03549124 0,08767976 ! regulation of lipid transport GO:0032368 13 7 0,000 0,03549124 0,08758568 ! positive regulation of interleukin-1 beta secretion GO:0050718 9 7 0,000 0,03549124 0,08749181 ! lipopolysaccharide-mediated signaling pathway GO:0031663 9 7 0,000 0,03549124 0,08739813 ! establishment or maintenance of epithelial cell apical/basal polarity GO:0045197 10 7 0,000 0,03549124 0,08730466 ! peptidyl-threonine modification GO:0018210 18 7 0,000 0,03549124 0,08721138 ! diuresis GO:0030146 12 7 0,000 0,03549124 0,08711831 GO:0030147|natriuresis, ! ubiquinone metabolic process GO:0006743 9 7 0,000 0,03549124 0,08702543 GO:0006744|ubiquinone biosynthetic process, GO:0045426|quinone cofactor biosynthetic process, ! positive regulation of epidermis development GO:0045684 11 7 0,000 0,03549124 0,08693275 ! negative regulation of osteoclast differentiation GO:0045671 10 7 0,000 0,03549124 0,08684027 ! positive regulation of leukocyte chemotaxis GO:0002690 14 7 0,000 0,03549124 0,08674799 GO:0002688|regulation of leukocyte chemotaxis, ! positive regulation of T-helper 2 cell differentiation GO:0045630 12 7 0,000 0,03549124 0,0866559 ! negative regulation of transmission of nerve impulse GO:0051970 14 7 0,000 0,03549124 0,086564 ! melanin biosynthetic process GO:0042438 8 7 0,000 0,03549124 0,08647231 ! regulation of synaptogenesis GO:0051963 10 7 0,000 0,03549124 0,0863808 ! serine family amino acid catabolic process GO:0009071 11 7 0,000 0,03549124 0,08628949 ! dopamine biosynthetic process GO:0042416 15 7 0,000 0,03549124 0,08619837 ! regulation of protein homodimerization activity GO:0043496 15 7 0,000 0,03549124 0,08610744 ! lymph node development GO:0048535 9 7 0,000 0,03549124 0,08601671 ! positive regulation of ATPase activity GO:0032781 10 7 0,000 0,03549124 0,08592616 ! negative regulation of viral reproduction GO:0048525 8 7 0,000 0,03549124 0,08583581 ! regulation of T cell mediated cytotoxicity GO:0001914 13 7 0,000 0,03549124 0,08574565 ! endosome to lysosome transport GO:0008333 10 7 0,000 0,03549124 0,08565567 ! ATP catabolic process GO:0006200 10 7 0,000 0,03549124 0,08556589 ! establishment of pigment granule localization GO:0051905 13 7 0,000 0,03549124 0,08547629 ! trophectodermal cell differentiation GO:0001829 8 7 0,000 0,03549124 0,08538688 ! negative regulation of telomere maintenance GO:0032205 9 7 0,000 0,03549124 0,08529766 ! negative regulation of calcium ion transport GO:0051926 9 7 0,000 0,03549124 0,08520862 ! toll-like receptor signaling pathway GO:0002224 7 7 0,000 0,03549124 0,08511977 ! positive regulation of NF-kappaB import into nucleus GO:0042346 12 7 0,000 0,03549124 0,0850311 ! muscle adaptation GO:0043500 12 7 0,000 0,03549124 0,08494262 ! amino sugar catabolic process GO:0046348 9 7 0,000 0,03549124 0,08485432 GO:0006043|glucosamine catabolic process, ! embryonic heart tube development GO:0035050 7 7 0,000 0,03549124 0,08476621 ! retina homeostasis GO:0001895 9 7 0,000 0,03549124 0,08467827 ! negative regulation of nucleotide metabolic process GO:0045980 9 7 0,000 0,03549124 0,08459052 ! B cell receptor signaling pathway GO:0050853 11 7 0,000 0,03549124 0,08450296 ! regulation of growth hormone secretion GO:0060123 11 7 0,000 0,03549124 0,08441557 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 11 7 0,000 0,03549124 0,08432836 ! behavioral response to nicotine GO:0035095 11 7 0,000 0,03549124 0,08424134 ! fusion of sperm to egg plasma membrane GO:0007342 8 7 0,000 0,03549124 0,08415449 ! defense response to Gram-negative bacterium GO:0050829 9 7 0,000 0,03549124 0,08406782 ! negative regulation of kinase activity GO:0033673 100 58 1,000 0,03596268 0,08509688 ! viral reproductive process GO:0022415 87 58 1,000 0,03596268 0,08500942 ! actin filament organization GO:0007015 95 59 1,000 0,03710231 0,08761326 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 90 60 1,000 0,03825573 0,0902443 ! embryonic limb morphogenesis GO:0030326 86 60 1,000 0,03825573 0,09015183 GO:0035113|embryonic appendage morphogenesis, ! regulation of homeostatic process GO:0032844 105 60 1,000 0,03825573 0,09005956 ! negative regulation of transferase activity GO:0051348 105 61 1,000 0,03942278 0,09271206 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 13 8 0,000 0,04045867 0,09505101 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 14 8 0,000 0,04045867 0,09495402 GO:0030804|positive regulation of cyclic nucleotide biosynthetic process, GO:0030810|positive regulation of nucleotide biosynthetic process, GO:0045981|positive regulation of nucleotide metabolic process, ! negative regulation of cyclin-dependent protein kinase activity GO:0045736 15 8 0,000 0,04045867 0,09485723 ! axon extension GO:0048675 11 8 0,000 0,04045867 0,09476063 ! negative regulation of smooth muscle cell proliferation GO:0048662 14 8 0,000 0,04045867 0,09466423 ! 'de novo' posttranslational protein folding GO:0051084 9 8 0,000 0,04045867 0,09456803 ! positive regulation of small GTPase mediated signal transduction GO:0051057 15 8 0,000 0,04045867 0,09447202 GO:0046579|positive regulation of Ras protein signal transduction, ! associative learning GO:0008306 15 8 0,000 0,04045867 0,09437621 ! DNA synthesis during DNA repair GO:0000731 9 8 0,000 0,04045867 0,09428059 ! cell proliferation in forebrain GO:0021846 10 8 0,000 0,04045867 0,09418516 ! positive regulation of B cell proliferation GO:0030890 11 8 0,000 0,04045867 0,09408993 ! phosphate transport GO:0006817 10 8 0,000 0,04045867 0,09399489 ! N-glycan processing GO:0006491 12 8 0,000 0,04045867 0,09390004 ! Golgi to endosome transport GO:0006895 16 8 0,000 0,04045867 0,09380538 ! UTP metabolic process GO:0046051 8 8 0,000 0,04045867 0,09371091 GO:0006183|GTP biosynthetic process, GO:0006228|UTP biosynthetic process, ! glycosaminoglycan catabolic process GO:0006027 10 8 0,000 0,04045867 0,09361664 ! prostaglandin biosynthetic process GO:0001516 13 8 0,000 0,04045867 0,09352255 GO:0046457|prostanoid biosynthetic process, ! neurotransmitter uptake GO:0001504 10 8 0,000 0,04045867 0,09342865 ! succinate metabolic process GO:0006105 14 8 0,000 0,04045867 0,09333494 ! smoothened signaling pathway GO:0007224 8 8 0,000 0,04045867 0,09324142 ! membrane hyperpolarization GO:0060081 10 8 0,000 0,04045867 0,09314809 ! detection of mechanical stimulus involved in sensory perception GO:0050974 11 8 0,000 0,04045867 0,09305494 ! keratinocyte proliferation GO:0043616 12 8 0,000 0,04045867 0,09296198 ! middle ear morphogenesis GO:0042474 9 8 0,000 0,04045867 0,0928692 ! chaperone-mediated protein complex assembly GO:0051131 12 8 0,000 0,04045867 0,09277661 ! amyloid precursor protein metabolic process GO:0042982 12 8 0,000 0,04045867 0,0926842 ! neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 19 8 0,000 0,04045867 0,09259198 ! ganglioside metabolic process GO:0001573 15 8 0,000 0,04045867 0,09249994 ! regulation of mesenchymal cell proliferation GO:0010464 10 8 0,000 0,04045867 0,09240808 ! pseudouridine synthesis GO:0001522 9 8 0,000 0,04045867 0,09231641 ! ribonucleoside triphosphate catabolic process GO:0009203 11 8 0,000 0,04045867 0,09222491 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! positive regulation of interferon-gamma biosynthetic process GO:0045078 8 8 0,000 0,04045867 0,0921336 ! endothelial cell differentiation GO:0045446 14 8 0,000 0,04045867 0,09204247 ! ceramide biosynthetic process GO:0046513 9 8 0,000 0,04045867 0,09195152 ! nerve growth factor receptor signaling pathway GO:0048011 10 8 0,000 0,04045867 0,09186075 ! astrocyte differentiation GO:0048708 16 8 0,000 0,04045867 0,09177016 ! embryonic cranial skeleton morphogenesis GO:0048701 11 8 0,000 0,04045867 0,09167974 ! inner mitochondrial membrane organization GO:0007007 11 8 0,000 0,04045867 0,09158951 ! cytoskeletal anchoring at plasma membrane GO:0007016 18 8 0,000 0,04045867 0,09149945 ! L-phenylalanine metabolic process GO:0006558 8 8 0,000 0,04045867 0,09140957 GO:0006559|L-phenylalanine catabolic process, ! polyamine biosynthetic process GO:0006596 9 8 0,000 0,04045867 0,09131986 ! melanin metabolic process GO:0006582 12 8 0,000 0,04045867 0,09123033 ! embryonic eye morphogenesis GO:0048048 12 8 0,000 0,04045867 0,09114098 ! elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) GO:0051482 12 8 0,000 0,04045867 0,0910518 ! macrophage activation GO:0042116 12 8 0,000 0,04045867 0,09096279 ! regulation of type I interferon production GO:0032479 8 8 0,000 0,04045867 0,09087396 ! regulation of muscle hypertrophy GO:0014743 11 8 0,000 0,04045867 0,09078531 GO:0010611|regulation of cardiac muscle hypertrophy, GO:0010612|regulation of cardiac muscle adaptation, ! retrograde transport, endosome to Golgi GO:0042147 12 8 0,000 0,04045867 0,09069682 ! regulation of multicellular organismal metabolic process GO:0044246 9 8 0,000 0,04045867 0,09060851 ! neurotransmitter catabolic process GO:0042135 13 8 0,000 0,04045867 0,09052037 ! positive regulation of calcium ion transport into cytosol GO:0010524 9 8 0,000 0,04045867 0,0904324 ! ruffle organization GO:0031529 11 8 0,000 0,04045867 0,0903446 ! osteoblast development GO:0002076 13 8 0,000 0,04045867 0,09025697 ! lens development in camera-type eye GO:0002088 10 8 0,000 0,04045867 0,09016951 ! positive regulation of vasodilation GO:0045909 12 8 0,000 0,04045867 0,09008223 ! intestinal cholesterol absorption GO:0030299 13 8 0,000 0,04045867 0,0899951 ! determination of anterior/posterior axis, embryo GO:0008595 10 8 0,000 0,04045867 0,08990815 GO:0007351|tripartite regional subdivision, ! regulation of Notch signaling pathway GO:0008593 18 8 0,000 0,04045867 0,08982137 ! regulation of smoothened signaling pathway GO:0008589 13 8 0,000 0,04045867 0,08973475 ! Schwann cell differentiation GO:0014037 17 8 0,000 0,04045867 0,0896483 ! chondroitin sulfate biosynthetic process GO:0030206 12 8 0,000 0,04045867 0,08956202 GO:0030204|chondroitin sulfate metabolic process, ! copper ion homeostasis GO:0055070 10 8 0,000 0,04045867 0,0894759 ! brain morphogenesis GO:0048854 20 8 0,000 0,04045867 0,08938995 ! oligodendrocyte development GO:0014003 8 8 0,000 0,04045867 0,08930416 ! segment specification GO:0007379 10 8 0,000 0,04045867 0,08921854 ! positive regulation of myeloid leukocyte differentiation GO:0002763 20 8 0,000 0,04045867 0,08913308 ! cellular extravasation GO:0045123 11 8 0,000 0,04045867 0,08904779 ! peptidyl-asparagine modification GO:0018196 13 8 0,000 0,04045867 0,08896266 GO:0018279|protein amino acid N-linked glycosylation via asparagine, ! pigment granule localization GO:0051875 14 8 0,000 0,04045867 0,08887769 ! thiamin and derivative metabolic process GO:0042723 8 8 0,000 0,04045867 0,08879288 ! regulation of T cell differentiation in the thymus GO:0033081 12 8 0,000 0,04045867 0,08870823 ! snRNA metabolic process GO:0016073 10 8 0,000 0,04045867 0,08862375 GO:0016180|snRNA processing, ! regulation of interleukin-4 production GO:0032673 16 8 0,000 0,04045867 0,08853943 ! regulation of protein kinase B signaling cascade GO:0051896 15 8 0,000 0,04045867 0,08845526 ! nucleoside bisphosphate metabolic process GO:0033865 12 8 0,000 0,04045867 0,08837126 ! regulation of mitochondrial membrane potential GO:0051881 11 8 0,000 0,04045867 0,08828742 ! nucleosome disassembly GO:0006337 12 8 0,000 0,04045867 0,08820373 GO:0032986|protein-DNA complex disassembly, GO:0031498|chromatin disassembly, ! molybdopterin cofactor biosynthetic process GO:0032324 10 8 0,000 0,04045867 0,08812021 GO:0051189|prosthetic group metabolic process, GO:0043545|molybdopterin cofactor metabolic process, GO:0006777|Mo-molybdopterin cofactor biosynthetic process, GO:0019720|Mo-molybdopterin cofactor metabolic process, ! positive regulation of Ras GTPase activity GO:0032320 20 8 0,000 0,04045867 0,08803684 ! protein import into peroxisome matrix GO:0016558 14 8 0,000 0,04045867 0,08795363 ! icosanoid secretion GO:0032309 12 8 0,000 0,04045867 0,08787057 GO:0050482|arachidonic acid secretion, ! induction of an organ GO:0001759 11 8 0,000 0,04045867 0,08778768 ! leukocyte activation during immune response GO:0002366 13 8 0,000 0,04045867 0,08770494 GO:0002263|cell activation during immune response, ! positive regulation of interferon-gamma production GO:0032729 9 8 0,000 0,04045867 0,08762235 ! cerebellum morphogenesis GO:0021587 9 8 0,000 0,04045867 0,08753992 GO:0021696|cerebellar cortex morphogenesis, GO:0021695|cerebellar cortex development, ! intracellular lipid transport GO:0032365 13 8 0,000 0,04045867 0,08745765 ! retinal ganglion cell axon guidance GO:0031290 10 8 0,000 0,04045867 0,08737553 ! morphogenesis of a polarized epithelium GO:0001738 9 8 0,000 0,04045867 0,08729356 ! regulation of transcription from RNA polymerase III promoter GO:0006359 10 8 0,000 0,04045867 0,08721175 ! sterol catabolic process GO:0016127 9 8 0,000 0,04045867 0,08713009 GO:0006707|cholesterol catabolic process, ! regulation of immune response to tumor cell GO:0002837 10 8 0,000 0,04045867 0,08704859 GO:0002839|positive regulation of immune response to tumor cell, GO:0002834|regulation of response to tumor cell, GO:0002833|positive regulation of response to biotic stimulus, GO:0002836|positive regulation of response to tumor cell, ! regulation of transcription initiation from RNA polymerase II promoter GO:0060260 11 8 0,000 0,04045867 0,08696723 ! positive regulation of interleukin-1 secretion GO:0050716 10 8 0,000 0,04045867 0,08688603 ! negative regulation of cytokine secretion GO:0050710 12 8 0,000 0,04045867 0,08680498 ! prophase GO:0051324 11 8 0,000 0,04045867 0,08672408 ! S phase GO:0051320 8 8 0,000 0,04045867 0,08664333 GO:0000084|S phase of mitotic cell cycle, ! regulation of interleukin-1 beta secretion GO:0050706 11 8 0,000 0,04045867 0,08656273 ! regulation of macrophage differentiation GO:0045649 14 8 0,000 0,04045867 0,08648228 ! neuromuscular process controlling posture GO:0050884 11 8 0,000 0,04045867 0,08640199 ! branched chain family amino acid catabolic process GO:0009083 11 8 0,000 0,04045867 0,08632184 ! regulation of synaptic transmission, glutamatergic GO:0051966 16 8 0,000 0,04045867 0,08624183 ! hormone catabolic process GO:0042447 13 8 0,000 0,04045867 0,08616198 ! quaternary ammonium group transport GO:0015697 10 8 0,000 0,04045867 0,08608227 ! myeloid cell homeostasis GO:0002262 8 8 0,000 0,04045867 0,08600272 ! regulation of fibrinolysis GO:0051917 13 8 0,000 0,04045867 0,0859233 ! quinone cofactor metabolic process GO:0042375 10 8 0,000 0,04045867 0,08584404 ! negative regulation of organic acid transport GO:0032891 12 8 0,000 0,04045867 0,08576492 ! regulation of telomere maintenance GO:0032204 10 8 0,000 0,04045867 0,08568595 ! pattern recognition receptor signaling pathway GO:0002221 8 8 0,000 0,04045867 0,08560712 ! regulation of calcium ion transport via voltage-gated calcium channel activity GO:0051925 9 8 0,000 0,04045867 0,08552844 ! regulation of synaptic transmission, GABAergic GO:0032228 13 8 0,000 0,04045867 0,0854499 ! negative regulation of blood vessel endothelial cell migration GO:0043537 17 8 0,000 0,04045867 0,0853715 ! pyrimidine nucleotide catabolic process GO:0006244 12 8 0,000 0,04045867 0,08529325 ! lamellipodium assembly GO:0030032 9 8 0,000 0,04045867 0,08521515 ! regulation of embryonic development GO:0045995 16 8 0,000 0,04045867 0,08513718 ! negative regulation of DNA replication initiation GO:0032297 9 8 0,000 0,04045867 0,08505936 GO:0000076|DNA replication checkpoint, ! mitochondrion localization GO:0051646 12 8 0,000 0,04045867 0,08498168 ! amine catabolic process GO:0009310 90 62 1,000 0,04060329 0,08520763 ! cAMP-mediated signaling GO:0019933 97 63 1,000 0,04179708 0,0876329 ! viral reproduction GO:0016032 92 63 1,000 0,04179708 0,08755309 ! appendage morphogenesis GO:0035107 93 64 1,000 0,04300401 0,08999928 GO:0035108|limb morphogenesis, ! regulation of actin cytoskeleton organization GO:0032956 97 64 1,000 0,04300401 0,08991747 ! adaptive immune response GO:0002250 94 64 1,000 0,04300401 0,0898358 GO:0002460|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, ! reproductive structure development GO:0048608 90 65 1,000 0,04422389 0,09230032 ! appendage development GO:0048736 94 65 1,000 0,04422389 0,09221664 GO:0060173|limb development, ! B cell activation GO:0042113 104 65 1,000 0,04422389 0,09213311 ! positive regulation of epidermal growth factor receptor signaling pathway GO:0045742 14 9 0,000 0,0454008 0,09449939 ! regulation of developmental growth GO:0048638 13 9 0,000 0,0454008 0,09441395 ! positive regulation of glucose metabolic process GO:0010907 15 9 0,000 0,0454008 0,09432866 ! telencephalon cell migration GO:0022029 16 9 0,000 0,0454008 0,09424353 ! regulation of epithelial cell differentiation GO:0030856 13 9 0,000 0,0454008 0,09415855 ! pentose-phosphate shunt GO:0006098 12 9 0,000 0,0454008 0,09407372 GO:0006740|NADPH regeneration, ! cell volume homeostasis GO:0006884 13 9 0,000 0,0454008 0,09398905 ! regulation of epidermal growth factor receptor activity GO:0007176 13 9 0,000 0,0454008 0,09390452 GO:0010469|regulation of receptor activity, ! CTP metabolic process GO:0046036 9 9 0,000 0,0454008 0,09382015 GO:0006241|CTP biosynthetic process, GO:0009208|pyrimidine ribonucleoside triphosphate metabolic process, GO:0009209|pyrimidine ribonucleoside triphosphate biosynthetic process, ! positive regulation of GTPase activity GO:0043547 21 9 0,000 0,0454008 0,09373593 ! GTP metabolic process GO:0046039 9 9 0,000 0,0454008 0,09365187 ! elastic fiber assembly GO:0048251 13 9 0,000 0,0454008 0,09356795 ! social behavior GO:0035176 14 9 0,000 0,0454008 0,09348418 ! regulation of activated T cell proliferation GO:0046006 15 9 0,000 0,0454008 0,09340056 ! artery development GO:0060840 19 9 0,000 0,0454008 0,0933171 GO:0048844|artery morphogenesis, ! regulation of histone modification GO:0031056 11 9 0,000 0,0454008 0,09323378 ! regulation of glycolysis GO:0006110 15 9 0,000 0,0454008 0,09315061 ! response to pain GO:0048265 16 9 0,000 0,0454008 0,09306758 ! protein complex disassembly GO:0043241 17 9 0,000 0,0454008 0,09298471 GO:0043624|cellular protein complex disassembly, ! muscarinic acetylcholine receptor signaling pathway GO:0007213 16 9 0,000 0,0454008 0,09290198 ! regulation of carbohydrate biosynthetic process GO:0043255 12 9 0,000 0,0454008 0,0928194 ! cytoplasmic sequestering of transcription factor GO:0042994 11 9 0,000 0,0454008 0,09273697 ! ciliary or flagellar motility GO:0001539 10 9 0,000 0,0454008 0,09265468 ! sphingoid biosynthetic process GO:0046520 11 9 0,000 0,0454008 0,09257254 ! regulation of exit from mitosis GO:0007096 12 9 0,000 0,0454008 0,09249055 ! ventral spinal cord development GO:0021517 11 9 0,000 0,0454008 0,0924087 ! protein targeting to ER GO:0045047 19 9 0,000 0,0454008 0,09232699 ! T cell selection GO:0045058 18 9 0,000 0,0454008 0,09224543 ! endoderm development GO:0007492 12 9 0,000 0,0454008 0,09216402 ! glycolipid biosynthetic process GO:0009247 11 9 0,000 0,0454008 0,09208274 GO:0006688|glycosphingolipid biosynthetic process, ! positive regulation of survival gene product expression GO:0045885 13 9 0,000 0,0454008 0,09200161 ! arginine catabolic process GO:0006527 10 9 0,000 0,0454008 0,09192062 ! myeloid leukocyte mediated immunity GO:0002444 11 9 0,000 0,0454008 0,09183978 ! telomere maintenance via telomerase GO:0007004 12 9 0,000 0,0454008 0,09175908 GO:0010833|telomere maintenance via telomere lengthening, ! L-serine metabolic process GO:0006563 13 9 0,000 0,0454008 0,09167852 ! phosphagen metabolic process GO:0006599 12 9 0,000 0,0454008 0,0915981 GO:0006600|creatine metabolic process, ! V(D)J recombination GO:0033151 12 9 0,000 0,0454008 0,09151782 ! regulation of phosphoprotein phosphatase activity GO:0043666 18 9 0,000 0,0454008 0,09143768 ! regulation of stress fiber formation GO:0051492 20 9 0,000 0,0454008 0,09135768 ! retinoic acid receptor signaling pathway GO:0048384 15 9 0,000 0,0454008 0,09127782 ! mannose metabolic process GO:0006013 9 9 0,000 0,0454008 0,0911981 ! substrate-bound cell migration GO:0006929 10 9 0,000 0,0454008 0,09111852 ! epithelial cell development GO:0002064 10 9 0,000 0,0454008 0,09103908 ! regulation of lipoprotein lipase activity GO:0051004 18 9 0,000 0,0454008 0,09095978 ! retinoic acid metabolic process GO:0042573 11 9 0,000 0,0454008 0,09088062 ! positive regulation of muscle contraction GO:0045933 12 9 0,000 0,0454008 0,09080159 ! positive regulation of translational initiation GO:0045948 10 9 0,000 0,0454008 0,0907227 ! acyl-CoA metabolic process GO:0006637 13 9 0,000 0,0454008 0,09064395 ! motor axon guidance GO:0008045 14 9 0,000 0,0454008 0,09056533 ! positive regulation of peptide secretion GO:0002793 15 9 0,000 0,0454008 0,09048685 ! alpha-beta T cell differentiation GO:0046632 14 9 0,000 0,0454008 0,09040851 ! positive regulation of phagocytosis GO:0050766 11 9 0,000 0,0454008 0,0903303 ! regulation of insulin receptor signaling pathway GO:0046626 13 9 0,000 0,0454008 0,09025223 ! blastoderm segmentation GO:0007350 11 9 0,000 0,0454008 0,09017429 ! base-excision repair, AP site formation GO:0006285 12 9 0,000 0,0454008 0,09009649 ! DNA ligation GO:0006266 14 9 0,000 0,0454008 0,09001882 ! purine nucleoside triphosphate catabolic process GO:0009146 12 9 0,000 0,0454008 0,08994128 ! response to amine stimulus GO:0014075 13 9 0,000 0,0454008 0,08986388 GO:0001975|response to amphetamine, GO:0010243|response to organic nitrogen, ! synaptic vesicle exocytosis GO:0016079 11 9 0,000 0,0454008 0,08978661 ! erythrocyte development GO:0048821 11 9 0,000 0,0454008 0,08970948 ! renal water homeostasis GO:0003091 14 9 0,000 0,0454008 0,08963247 ! postreplication repair GO:0006301 11 9 0,000 0,0454008 0,0895556 ! mRNA cleavage GO:0006379 13 9 0,000 0,0454008 0,08947886 ! hindbrain morphogenesis GO:0021575 12 9 0,000 0,0454008 0,08940225 ! regulation of hormone metabolic process GO:0032350 15 9 0,000 0,0454008 0,08932577 ! regulation of DNA replication initiation GO:0030174 13 9 0,000 0,0454008 0,08924943 ! cellular metabolic compound salvage GO:0043094 11 9 0,000 0,0454008 0,08917321 ! negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 16 9 0,000 0,0454008 0,08909712 GO:0002820|negative regulation of adaptive immune response, ! regulation of interleukin-1 secretion GO:0050704 12 9 0,000 0,0454008 0,08902117 ! positive regulation of erythrocyte differentiation GO:0045648 19 9 0,000 0,0454008 0,08894534 ! acid secretion GO:0046717 14 9 0,000 0,0454008 0,08886964 ! musculoskeletal movement GO:0050881 11 9 0,000 0,0454008 0,08879407 GO:0050879|multicellular organismal movement, ! negative regulation of lymphocyte differentiation GO:0045620 11 9 0,000 0,0454008 0,08871863 ! methionine biosynthetic process GO:0009086 10 9 0,000 0,0454008 0,08864332 ! purine base metabolic process GO:0006144 18 9 0,000 0,0454008 0,08856813 ! thymus development GO:0048538 15 9 0,000 0,0454008 0,08849308 ! spleen development GO:0048536 15 9 0,000 0,0454008 0,08841815 ! negative regulation of BMP signaling pathway GO:0030514 13 9 0,000 0,0454008 0,08834334 ! anterior/posterior axis specification GO:0009948 11 9 0,000 0,0454008 0,08826866 ! regulation of RNA splicing GO:0043484 14 9 0,000 0,0454008 0,08819411 ! detection of calcium ion GO:0005513 13 9 0,000 0,0454008 0,08811969 ! blastocyst formation GO:0001825 12 9 0,000 0,0454008 0,08804539 ! pyrimidine base metabolic process GO:0006206 14 9 0,000 0,0454008 0,08797121 ! establishment or maintenance of apical/basal cell polarity GO:0035088 15 9 0,000 0,0454008 0,08789716 ! natural killer cell mediated immunity GO:0002228 13 9 0,000 0,0454008 0,08782324 GO:0042267|natural killer cell mediated cytotoxicity, ! regulation of muscle adaptation GO:0043502 12 9 0,000 0,0454008 0,08774944 ! regulation of amino acid transport GO:0051955 11 9 0,000 0,0454008 0,08767576 ! positive regulation of amine transport GO:0051954 15 9 0,000 0,0454008 0,08760221 ! defense response to Gram-positive bacterium GO:0050830 10 9 0,000 0,0454008 0,08752878 ! prepulse inhibition GO:0060134 14 9 0,000 0,0454008 0,08745547 ! embryonic placenta development GO:0001892 12 9 0,000 0,0454008 0,08738228 ! positive regulation of protein polymerization GO:0032273 15 9 0,000 0,0454008 0,08730922 ! insulin secretion GO:0030073 17 9 0,000 0,0454008 0,08723628 ! sequestering of metal ion GO:0051238 11 9 0,000 0,0454008 0,08716346 ! response to nicotine GO:0035094 16 9 0,000 0,0454008 0,08709077 ! establishment of cell polarity GO:0030010 12 9 0,000 0,0454008 0,08701819 ! nucleus localization GO:0051647 15 9 0,000 0,0454008 0,08694574 ! regulation of synapse organization GO:0050807 12 9 0,000 0,0454008 0,0868734 ! localization within membrane GO:0051668 15 9 0,000 0,0454008 0,08680119 ! regulation of actin filament-based process GO:0032970 99 66 1,000 0,04545658 0,08683566 ! axon guidance GO:0007411 99 66 1,000 0,04545658 0,08676359 ! learning or memory GO:0007611 123 68 1,000 0,04795971 0,09146546 ! development of primary sexual characteristics GO:0045137 92 68 1,000 0,04795971 0,09138968 ! intracellular protein transmembrane transport GO:0065002 102 68 1,000 0,04795971 0,09131402 ! response to drug GO:0042493 108 69 1,000 0,04922984 0,09365479 ! very-long-chain fatty acid metabolic process GO:0000038 16 10 0,000 0,05031775 0,09564531 ! neuron fate specification GO:0048665 11 10 0,000 0,05031775 0,09556633 ! negative regulation of blood pressure GO:0045776 22 10 0,000 0,05031775 0,09548748 ! cortical actin cytoskeleton organization GO:0030866 19 10 0,000 0,05031775 0,09540876 ! thyroid gland development GO:0030878 19 10 0,000 0,05031775 0,09533017 ! regulation of B cell proliferation GO:0030888 15 10 0,000 0,05031775 0,09525171 ! regulation of phosphatase activity GO:0010921 21 10 0,000 0,05031775 0,09517337 ! synapsis GO:0007129 13 10 0,000 0,05031775 0,09509517 GO:0070192|chromosome organization involved in meiosis, ! folic acid and derivative biosynthetic process GO:0009396 10 10 0,000 0,05031775 0,0950171 ! regulation of long-term neuronal synaptic plasticity GO:0048169 23 10 0,000 0,05031775 0,09493915 ! syncytium formation by plasma membrane fusion GO:0000768 13 10 0,000 0,05031775 0,09486133 GO:0007520|myoblast fusion, ! hair follicle morphogenesis GO:0031069 17 10 0,000 0,05031775 0,09478364 ! sulfate transport GO:0008272 12 10 0,000 0,05031775 0,09470607 ! COPI coating of Golgi vesicle GO:0048205 14 10 0,000 0,05031775 0,09462864 GO:0048200|Golgi transport vesicle coating, ! regulation of cell projection assembly GO:0060491 20 10 0,000 0,05031775 0,09455133 ! androgen metabolic process GO:0008209 13 10 0,000 0,05031775 0,09447414 ! phospholipid efflux GO:0033700 16 10 0,000 0,05031775 0,09439708 ! positive regulation of heart contraction GO:0045823 14 10 0,000 0,05031775 0,09432015 ! positive regulation of lipid metabolic process GO:0045834 12 10 0,000 0,05031775 0,09424334 ! negative regulation of cell-matrix adhesion GO:0001953 27 10 0,000 0,05031775 0,09416666 GO:0010812|negative regulation of cell-substrate adhesion, ! negative regulation of lipid metabolic process GO:0045833 14 10 0,000 0,05031775 0,0940901 ! pathogenesis GO:0009405 13 10 0,000 0,05031775 0,09401367 ! regulation of interferon-gamma biosynthetic process GO:0045072 11 10 0,000 0,05031775 0,09393736 ! regulation of chemokine biosynthetic process GO:0045073 12 10 0,000 0,05031775 0,09386117 ! two-component signal transduction system (phosphorelay) GO:0000160 14 10 0,000 0,05031775 0,09378511 ! regulation of catecholamine secretion GO:0050433 18 10 0,000 0,05031775 0,09370917 ! melanocyte differentiation GO:0030318 15 10 0,000 0,05031775 0,09363335 GO:0050931|pigment cell differentiation, ! glucan biosynthetic process GO:0009250 13 10 0,000 0,05031775 0,09355766 GO:0005978|glycogen biosynthetic process, ! polyamine metabolic process GO:0006595 14 10 0,000 0,05031775 0,09348209 ! reverse cholesterol transport GO:0043691 16 10 0,000 0,05031775 0,09340664 ! B cell proliferation GO:0042100 14 10 0,000 0,05031775 0,09333131 ! nucleobase biosynthetic process GO:0046112 21 10 0,000 0,05031775 0,0932561 ! regulation of sodium ion transport GO:0002028 15 10 0,000 0,05031775 0,09318102 ! forebrain cell migration GO:0021885 17 10 0,000 0,05031775 0,09310605 ! lipid digestion GO:0044241 15 10 0,000 0,05031775 0,09303121 ! phagocytosis, engulfment GO:0006911 20 10 0,000 0,05031775 0,09295648 ! neurotransmitter biosynthetic process GO:0042136 14 10 0,000 0,05031775 0,09288188 ! UV protection GO:0009650 14 10 0,000 0,05031775 0,0928074 ! entry into host cell GO:0030260 20 10 0,000 0,05031775 0,09273303 GO:0044409|entry into host, GO:0051828|entry into other organism during symbiotic interaction, GO:0051806|entry into cell of other organism during symbiotic interaction, GO:0052192|movement in environment of other organism during symbiotic interaction, GO:0052126|movement in host environment, GO:0046718|entry of virus into host cell, ! fear response GO:0042596 16 10 0,000 0,05031775 0,09265879 ! heparan sulfate proteoglycan biosynthetic process GO:0015012 13 10 0,000 0,05031775 0,09258466 ! negative regulation of ossification GO:0030279 19 10 0,000 0,05031775 0,09251065 ! positive regulation vascular endothelial growth factor production GO:0010575 18 10 0,000 0,05031775 0,09243676 ! alpha-beta T cell activation GO:0046631 16 10 0,000 0,05031775 0,09236299 ! regulation of organ growth GO:0046620 11 10 0,000 0,05031775 0,09228933 ! response to dsRNA GO:0043331 18 10 0,000 0,05031775 0,09221579 ! RNA-dependent DNA replication GO:0006278 13 10 0,000 0,05031775 0,09214237 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 10 10 0,000 0,05031775 0,09206907 ! embryonic axis specification GO:0000578 12 10 0,000 0,05031775 0,09199588 ! regulation of B cell differentiation GO:0045577 16 10 0,000 0,05031775 0,09192281 ! purine ribonucleotide catabolic process GO:0009154 14 10 0,000 0,05031775 0,09184986 ! positive regulation of interleukin-6 production GO:0032755 13 10 0,000 0,05031775 0,09177702 ! fucose catabolic process GO:0019317 16 10 0,000 0,05031775 0,0917043 GO:0042355|L-fucose catabolic process, ! DNA methylation GO:0006306 15 10 0,000 0,05031775 0,09163169 GO:0006305|DNA alkylation, ! mRNA polyadenylation GO:0006378 18 10 0,000 0,05031775 0,0915592 ! protein sumoylation GO:0016925 12 10 0,000 0,05031775 0,09148682 ! negative regulation of tumor necrosis factor production GO:0032720 14 10 0,000 0,05031775 0,09141455 ! negative regulation of MAPKKK cascade GO:0043409 20 10 0,000 0,05031775 0,0913424 ! zymogen activation GO:0031638 14 10 0,000 0,05031775 0,09127036 ! salivary gland development GO:0007431 22 10 0,000 0,05031775 0,09119844 ! negative regulation of neurological system process GO:0031645 19 10 0,000 0,05031775 0,09112663 ! glutathione biosynthetic process GO:0006750 11 10 0,000 0,05031775 0,09105494 ! positive regulation of acute inflammatory response GO:0002675 14 10 0,000 0,05031775 0,09098335 ! positive regulation of neuron differentiation GO:0045666 12 10 0,000 0,05031775 0,09091188 ! nitric oxide mediated signal transduction GO:0007263 17 10 0,000 0,05031775 0,09084052 ! multicellular organismal water homeostasis GO:0050891 15 10 0,000 0,05031775 0,09076927 ! thyroid hormone metabolic process GO:0042403 14 10 0,000 0,05031775 0,09069814 ! positive regulation of viral reproduction GO:0048524 15 10 0,000 0,05031775 0,09062711 ! regulation of cellular carbohydrate catabolic process GO:0043471 16 10 0,000 0,05031775 0,0905562 GO:0043470|regulation of carbohydrate catabolic process, ! positive regulation of JNK cascade GO:0046330 14 10 0,000 0,05031775 0,0904854 ! embryonic gut development GO:0048566 11 10 0,000 0,05031775 0,09041471 ! activation of innate immune response GO:0002218 10 10 0,000 0,05031775 0,09034412 GO:0002758|innate immune response-activating signal transduction, ! regulation of actin filament bundle formation GO:0032231 21 10 0,000 0,05031775 0,09027365 ! cardiac cell differentiation GO:0035051 16 10 0,000 0,05031775 0,09020329 ! developmental induction GO:0031128 13 10 0,000 0,05031775 0,09013304 GO:0045168|cell-cell signaling involved in cell fate specification, ! T cell receptor signaling pathway GO:0050852 18 10 0,000 0,05031775 0,0900629 ! regulation of synapse structure and activity GO:0050803 13 10 0,000 0,05031775 0,08999286 ! negative regulation of immune effector process GO:0002698 16 10 0,000 0,05031775 0,08992294 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 104 70 1,000 0,05051214 0,09020024 ! negative regulation of organelle organization GO:0010639 115 72 1,000 0,0531126 0,09477035 ! mitochondrion organization GO:0007005 104 73 1,000 0,05443046 0,09704656 ! response to steroid hormone stimulus GO:0048545 114 73 1,000 0,05443046 0,09697138 ! rRNA transcription GO:0009303 17 11 0,000 0,05520966 0,09828344 ! respiratory burst GO:0045730 14 11 0,000 0,05520966 0,09820743 ! ER-associated protein catabolic process GO:0030433 14 11 0,000 0,05520966 0,09813154 GO:0006515|misfolded or incompletely synthesized protein catabolic process, ! regulation of membrane protein ectodomain proteolysis GO:0051043 16 11 0,000 0,05520966 0,09805576 ! cortical cytoskeleton organization GO:0030865 20 11 0,000 0,05520966 0,0979801 ! virus-host interaction GO:0019048 17 11 0,000 0,05520966 0,09790456 ! regulation of nitric-oxide synthase activity GO:0050999 20 11 0,000 0,05520966 0,09782913 ! filopodium assembly GO:0046847 19 11 0,000 0,05520966 0,09775382 ! Golgi vesicle budding GO:0048194 17 11 0,000 0,05520966 0,09767862 ! RNA polyadenylation GO:0043631 19 11 0,000 0,05520966 0,09760354 ! detection of mechanical stimulus GO:0050982 15 11 0,000 0,05520966 0,09752858 ! mating GO:0007618 14 11 0,000 0,05520966 0,09745373 ! T cell proliferation GO:0042098 20 11 0,000 0,05520966 0,09737899 ! positive regulation of stress-activated protein kinase signaling pathway GO:0070304 17 11 0,000 0,05520966 0,09730437 ! bone resorption GO:0045453 16 11 0,000 0,05520966 0,09722987 ! regulated secretory pathway GO:0045055 14 11 0,000 0,05520966 0,09715548 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 18 11 0,000 0,05520966 0,0970812 GO:0050654|chondroitin sulfate proteoglycan metabolic process, ! negative regulation of proteolysis GO:0045861 16 11 0,000 0,05520966 0,09700704 ! pyrimidine deoxyribonucleotide metabolic process GO:0009219 16 11 0,000 0,05520966 0,09693298 ! syncytium formation GO:0006949 15 11 0,000 0,05520966 0,09685905 ! plasma membrane organization GO:0007009 18 11 0,000 0,05520966 0,09678522 ! ribonucleotide catabolic process GO:0009261 16 11 0,000 0,05520966 0,09671151 ! focal adhesion formation GO:0048041 24 11 0,000 0,05520966 0,09663791 ! mitotic spindle organization GO:0007052 15 11 0,000 0,05520966 0,09656442 ! cellular carbohydrate catabolic process GO:0044275 13 11 0,000 0,05520966 0,09649104 ! membrane protein proteolysis GO:0033619 18 11 0,000 0,05520966 0,09641777 GO:0006509|membrane protein ectodomain proteolysis, ! regulation of calcium ion transport into cytosol GO:0010522 13 11 0,000 0,05520966 0,09634462 ! adult heart development GO:0007512 11 11 0,000 0,05520966 0,09627158 ! chondrocyte differentiation GO:0002062 17 11 0,000 0,05520966 0,09619864 ! temperature homeostasis GO:0001659 16 11 0,000 0,05520966 0,09612582 ! L-glutamate transport GO:0015813 16 11 0,000 0,05520966 0,09605311 GO:0015800|acidic amino acid transport, ! regulation of vascular endothelial growth factor production GO:0010574 19 11 0,000 0,05520966 0,09598051 ! heparan sulfate proteoglycan metabolic process GO:0030201 16 11 0,000 0,05520966 0,09590801 ! protein targeting to peroxisome GO:0006625 20 11 0,000 0,05520966 0,09583563 ! stem cell development GO:0048864 29 11 0,000 0,05520966 0,09576336 GO:0019827|stem cell maintenance, ! protein homotetramerization GO:0051289 18 11 0,000 0,05520966 0,09569119 ! negative regulation of myeloid leukocyte differentiation GO:0002762 15 11 0,000 0,05520966 0,09561913 ! regulation of phagocytosis GO:0050764 14 11 0,000 0,05520966 0,09554719 ! positive regulation of T cell mediated immunity GO:0002711 18 11 0,000 0,05520966 0,09547535 ! vasoconstriction GO:0042310 15 11 0,000 0,05520966 0,09540361 ! nucleoside triphosphate catabolic process GO:0009143 15 11 0,000 0,05520966 0,09533199 ! regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 19 11 0,000 0,05520966 0,09526047 ! regulation of interleukin-8 production GO:0032677 17 11 0,000 0,05520966 0,09518906 ! regulation of Rho GTPase activity GO:0032319 18 11 0,000 0,05520966 0,09511776 ! ribosome assembly GO:0042255 13 11 0,000 0,05520966 0,09504656 ! nitric oxide metabolic process GO:0046209 14 11 0,000 0,05520966 0,09497547 GO:0006809|nitric oxide biosynthetic process, ! histone deacetylation GO:0016575 13 11 0,000 0,05520966 0,09490449 ! chromatin silencing GO:0006342 19 11 0,000 0,05520966 0,09483361 ! nucleosome positioning GO:0016584 13 11 0,000 0,05520966 0,09476284 ! T cell homeostasis GO:0043029 20 11 0,000 0,05520966 0,09469218 ! regulation of isotype switching GO:0045191 19 11 0,000 0,05520966 0,09462162 ! regulation of osteoclast differentiation GO:0045670 15 11 0,000 0,05520966 0,09455116 ! protein-chromophore linkage GO:0018298 13 11 0,000 0,05520966 0,09448081 ! regulation of T-helper 2 cell differentiation GO:0045628 17 11 0,000 0,05520966 0,09441056 ! serine family amino acid biosynthetic process GO:0009070 13 11 0,000 0,05520966 0,09434042 ! somatic diversification of immunoglobulins during immune response GO:0002208 19 11 0,000 0,05520966 0,09427039 GO:0002204|somatic recombination of immunoglobulin genes during immune response, GO:0045190|isotype switching, ! oxygen transport GO:0015671 15 11 0,000 0,05520966 0,09420045 ! male genitalia development GO:0030539 13 11 0,000 0,05520966 0,09413062 ! cholesterol efflux GO:0033344 19 11 0,000 0,05520966 0,0940609 ! digestive tract morphogenesis GO:0048546 15 11 0,000 0,05520966 0,09399127 GO:0048547|gut morphogenesis, GO:0055123|digestive system development, ! leukocyte mediated cytotoxicity GO:0001909 17 11 0,000 0,05520966 0,09392175 ! negative regulation of glucose import GO:0046325 14 11 0,000 0,05520966 0,09385233 GO:0010829|negative regulation of glucose transport, ! germ cell migration GO:0008354 18 11 0,000 0,05520966 0,09378302 ! regulation of organic acid transport GO:0032890 17 11 0,000 0,05520966 0,09371381 ! negative regulation of mast cell proliferation GO:0070667 17 11 0,000 0,05520966 0,0936447 GO:0042130|negative regulation of T cell proliferation, ! defense response to fungus GO:0050832 12 11 0,000 0,05520966 0,09357569 ! mRNA 3'-end processing GO:0031124 19 11 0,000 0,05520966 0,09350678 ! lysogeny GO:0030069 18 11 0,000 0,05520966 0,09343798 GO:0019047|provirus integration, ! actin filament polymerization GO:0030041 17 11 0,000 0,05520966 0,09336927 ! acrosome reaction GO:0007340 13 11 0,000 0,05520966 0,09330067 ! regulation of steroid biosynthetic process GO:0050810 11 11 0,000 0,05520966 0,09323217 ! cellular response to hormone stimulus GO:0032870 109 74 1,000 0,05575987 0,09409222 ! cofactor biosynthetic process GO:0051188 92 75 1,000 0,05710068 0,09628413 ! tRNA metabolic process GO:0006399 95 76 1,000 0,05845274 0,09849179 ! response to unfolded protein GO:0006986 99 76 1,000 0,05845274 0,09841969 ! regulation of adenylate cyclase activity GO:0045761 131 77 1,000 0,05981589 0,10064123 ! gland development GO:0048732 148 77 1,000 0,05981589 0,10056766 ! sex differentiation GO:0007548 105 77 1,000 0,05981589 0,1004942 ! protein ubiquitination GO:0016567 125 77 1,000 0,05981589 0,10042084 ! lactation GO:0007595 20 12 0,000 0,06007664 0,10078503 ! reproductive cellular process GO:0048610 14 12 0,000 0,06007664 0,10071157 ! tRNA modification GO:0006400 14 12 0,000 0,06007664 0,10063822 ! positive regulation of blood pressure GO:0045777 16 12 0,000 0,06007664 0,10056498 ! positive regulation of cellular catabolic process GO:0031331 22 12 0,000 0,06007664 0,10049184 ! 'de novo' protein folding GO:0006458 18 12 0,000 0,06007664 0,10041881 ! dicarboxylic acid transport GO:0006835 22 12 0,000 0,06007664 0,10034588 ! non-recombinational repair GO:0000726 19 12 0,000 0,06007664 0,10027306 GO:0006303|double-strand break repair via nonhomologous end joining, ! phospholipid catabolic process GO:0009395 14 12 0,000 0,06007664 0,10020035 ! peroxisomal transport GO:0043574 21 12 0,000 0,06007664 0,10012774 ! cartilage condensation GO:0001502 18 12 0,000 0,06007664 0,10005523 ! negative regulation of transcription factor import into nucleus GO:0042992 24 12 0,000 0,06007664 0,09998284 ! cytokine biosynthetic process GO:0042089 16 12 0,000 0,06007664 0,09991054 ! auditory receptor cell differentiation GO:0042491 25 12 0,000 0,06007664 0,09983835 ! heart looping GO:0001947 15 12 0,000 0,06007664 0,09976627 ! palate development GO:0060021 15 12 0,000 0,06007664 0,09969429 ! positive regulation of cell growth GO:0030307 16 12 0,000 0,06007664 0,09962241 ! regulation of skeletal muscle fiber development GO:0048742 20 12 0,000 0,06007664 0,09955063 ! nucleotide-sugar metabolic process GO:0009225 14 12 0,000 0,06007664 0,09947896 ! arginine metabolic process GO:0006525 13 12 0,000 0,06007664 0,0994074 ! glycoprotein catabolic process GO:0006516 19 12 0,000 0,06007664 0,09933593 ! methionine metabolic process GO:0006555 13 12 0,000 0,06007664 0,09926457 ! tyrosine metabolic process GO:0006570 14 12 0,000 0,06007664 0,09919331 ! Golgi organization GO:0007030 18 12 0,000 0,06007664 0,09912215 ! cell-cell junction assembly GO:0007043 18 12 0,000 0,06007664 0,0990511 ! negative regulation of endothelial cell migration GO:0010596 21 12 0,000 0,06007664 0,09898014 ! monoamine transport GO:0015844 13 12 0,000 0,06007664 0,09890929 ! positive regulation of activation of JAK2 kinase activity GO:0010535 12 12 0,000 0,06007664 0,09883854 GO:0010536|positive regulation of activation of Janus kinase activity, GO:0010533|regulation of activation of Janus kinase activity, GO:0010534|regulation of activation of JAK2 kinase activity, GO:0002090|regulation of receptor internalization, GO:0002092|positive regulation of receptor internalization, ! positive regulation of carbohydrate metabolic process GO:0045913 20 12 0,000 0,06007664 0,09876789 GO:0010676|positive regulation of cellular carbohydrate metabolic process, ! neutral amino acid transport GO:0015804 19 12 0,000 0,06007664 0,09869734 ! L-amino acid transport GO:0015807 20 12 0,000 0,06007664 0,09862689 ! positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 12 0,000 0,06007664 0,09855655 GO:0002717|positive regulation of natural killer cell mediated immunity, ! phosphatidylcholine biosynthetic process GO:0006656 17 12 0,000 0,06007664 0,0984863 ! cotranslational protein targeting to membrane GO:0006613 20 12 0,000 0,06007664 0,09841615 ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 13 12 0,000 0,06007664 0,09834611 ! regulation of interleukin-12 production GO:0032655 16 12 0,000 0,06007664 0,09827616 ! ribosomal large subunit biogenesis GO:0042273 12 12 0,000 0,06007664 0,09820631 ! cerebellum development GO:0021549 13 12 0,000 0,06007664 0,09813656 ! gastrulation with mouth forming second GO:0001702 15 12 0,000 0,06007664 0,09806691 ! immunoglobulin production during immune response GO:0002381 20 12 0,000 0,06007664 0,09799736 ! histone methylation GO:0016571 15 12 0,000 0,06007664 0,09792791 ! gland morphogenesis GO:0022612 23 12 0,000 0,06007664 0,09785855 ! positive regulation of cytokine secretion GO:0050715 16 12 0,000 0,06007664 0,0977893 ! negative regulation of protein secretion GO:0050709 20 12 0,000 0,06007664 0,09772014 ! regulation of epidermis development GO:0045682 17 12 0,000 0,06007664 0,09765108 ! intestinal absorption GO:0050892 19 12 0,000 0,06007664 0,09758212 ! glutamine family amino acid biosynthetic process GO:0009084 13 12 0,000 0,06007664 0,09751325 ! cAMP biosynthetic process GO:0006171 20 12 0,000 0,06007664 0,09744448 ! regulation of fatty acid oxidation GO:0046320 18 12 0,000 0,06007664 0,09737581 ! positive regulation of homeostatic process GO:0032846 15 12 0,000 0,06007664 0,09730724 ! RNA 3'-end processing GO:0031123 20 12 0,000 0,06007664 0,09723876 ! microspike assembly GO:0030035 23 12 0,000 0,06007664 0,09717038 ! positive regulation of calcium-mediated signaling GO:0050850 17 12 0,000 0,06007664 0,09710209 ! response to cold GO:0009409 14 12 0,000 0,06007664 0,0970339 ! nitrogen compound catabolic process GO:0044270 114 78 1,000 0,06119001 0,09876282 ! regulation of cyclase activity GO:0031279 132 78 1,000 0,06119001 0,09869356 ! regulation of cAMP biosynthetic process GO:0030817 136 79 1,000 0,06257492 0,10085657 ! regulation of lyase activity GO:0051339 133 79 1,000 0,06257492 0,10078594 ! forebrain development GO:0030900 131 80 1,000 0,06397051 0,10296163 ! positive regulation of protein complex assembly GO:0031334 19 13 0,000 0,06491884 0,10441491 ! pteridine and derivative biosynthetic process GO:0042559 15 13 0,000 0,06491884 0,10434194 ! cGMP metabolic process GO:0046068 16 13 0,000 0,06491884 0,10426908 GO:0006182|cGMP biosynthetic process, ! regulation of chemokine production GO:0032642 17 13 0,000 0,06491884 0,10419632 ! water transport GO:0006833 17 13 0,000 0,06491884 0,10412366 GO:0042044|fluid transport, ! copper ion transport GO:0006825 15 13 0,000 0,06491884 0,1040511 ! regulation of cell-cell adhesion GO:0022407 27 13 0,000 0,06491884 0,10397864 ! lipid localization GO:0010876 24 13 0,000 0,06491884 0,10390628 GO:0019915|lipid storage, ! Wnt receptor signaling pathway, calcium modulating pathway GO:0007223 15 13 0,000 0,06491884 0,10383402 ! negative regulation of cytokine biosynthetic process GO:0042036 18 13 0,000 0,06491884 0,10376186 ! organelle fusion GO:0048284 28 13 0,000 0,06491884 0,10368981 ! regulation of transmembrane transporter activity GO:0022898 19 13 0,000 0,06491884 0,10361785 GO:0032409|regulation of transporter activity, GO:0032412|regulation of ion transmembrane transporter activity, ! endocrine pancreas development GO:0031018 19 13 0,000 0,06491884 0,10354599 ! negative regulation of protein amino acid phosphorylation GO:0001933 27 13 0,000 0,06491884 0,10347424 ! cell differentiation in spinal cord GO:0021515 16 13 0,000 0,06491884 0,10340258 ! photoreceptor cell maintenance GO:0045494 17 13 0,000 0,06491884 0,10333102 ! response to hexose stimulus GO:0009746 19 13 0,000 0,06491884 0,10325956 GO:0009749|response to glucose stimulus, GO:0034284|response to monosaccharide stimulus, ! induction of apoptosis via death domain receptors GO:0008625 15 13 0,000 0,06491884 0,1031882 ! glutamate metabolic process GO:0006536 18 13 0,000 0,06491884 0,10311694 ! deoxyribonucleotide catabolic process GO:0009264 16 13 0,000 0,06491884 0,10304577 ! nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process GO:0034654 24 13 0,000 0,06491884 0,1029747 GO:0034404|nucleobase, nucleoside and nucleotide biosynthetic process, ! cytokine metabolic process GO:0042107 17 13 0,000 0,06491884 0,10290374 ! exocrine system development GO:0035272 27 13 0,000 0,06491884 0,10283287 ! negative regulation of mitotic cell cycle GO:0045930 23 13 0,000 0,06491884 0,10276209 ! bone mineralization GO:0030282 15 13 0,000 0,06491884 0,10269142 ! regulation of exocytosis GO:0017157 17 13 0,000 0,06491884 0,10262084 ! regulation of cytokine production during immune response GO:0002718 18 13 0,000 0,06491884 0,10255036 ! regulation of natural killer cell mediated immunity GO:0002715 19 13 0,000 0,06491884 0,10247997 GO:0042269|regulation of natural killer cell mediated cytotoxicity, ! regulation of DNA repair GO:0006282 15 13 0,000 0,06491884 0,10240969 ! negative regulation of protein import into nucleus GO:0042308 25 13 0,000 0,06491884 0,10233949 ! genitalia development GO:0048806 15 13 0,000 0,06491884 0,1022694 ! regulation of monooxygenase activity GO:0032768 26 13 0,000 0,06491884 0,1021994 ! cellular pigmentation GO:0033059 24 13 0,000 0,06491884 0,1021295 ! tissue regeneration GO:0042246 21 13 0,000 0,06491884 0,10205969 ! positive regulation of bone mineralization GO:0030501 19 13 0,000 0,06491884 0,10198997 ! cofactor transport GO:0051181 19 13 0,000 0,06491884 0,10192036 ! NADP metabolic process GO:0006739 18 13 0,000 0,06491884 0,10185083 ! neuromuscular synaptic transmission GO:0007274 20 13 0,000 0,06491884 0,10178141 ! regulation of acute inflammatory response GO:0002673 19 13 0,000 0,06491884 0,10171207 ! gas transport GO:0015669 18 13 0,000 0,06491884 0,10164283 ! heme biosynthetic process GO:0006783 20 13 0,000 0,06491884 0,10157369 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 22 13 0,000 0,06491884 0,10150464 ! lymphocyte homeostasis GO:0002260 24 13 0,000 0,06491884 0,10143568 ! positive regulation of calcium ion transport GO:0051928 14 13 0,000 0,06491884 0,10136682 GO:0043270|positive regulation of ion transport, ! L-fucose metabolic process GO:0042354 20 13 0,000 0,06491884 0,10129805 ! regulation of NF-kappaB import into nucleus GO:0042345 23 13 0,000 0,06491884 0,10122937 ! regulation of calcium-mediated signaling GO:0050848 18 13 0,000 0,06491884 0,10116079 ! regulation of cAMP metabolic process GO:0030814 141 81 1,000 0,06537661 0,10180514 ! mRNA transport GO:0051028 121 81 1,000 0,06537661 0,10173626 ! regulation of cell cycle process GO:0010564 122 81 1,000 0,06537661 0,10166748 ! response to protein stimulus GO:0051789 111 81 1,000 0,06537661 0,10159878 ! vitamin metabolic process GO:0006766 103 81 1,000 0,06537661 0,10153018 ! regulation of nucleotide biosynthetic process GO:0030808 141 83 1,000 0,0682198 0,10587418 GO:0030802|regulation of cyclic nucleotide biosynthetic process, ! biogenic amine metabolic process GO:0006576 121 83 1,000 0,0682198 0,10580279 ! regulation of skeletal muscle tissue development GO:0048641 22 14 0,000 0,06973636 0,10808196 ! G1 phase of mitotic cell cycle GO:0000080 23 14 0,000 0,06973636 0,10800917 ! superoxide anion generation GO:0042554 18 14 0,000 0,06973636 0,10793649 ! neuron maturation GO:0042551 21 14 0,000 0,06973636 0,1078639 ! regulation of lipid biosynthetic process GO:0046890 16 14 0,000 0,06973636 0,10779141 ! myotube differentiation GO:0014902 21 14 0,000 0,06973636 0,10771902 ! heterophilic cell adhesion GO:0007157 29 14 0,000 0,06973636 0,10764673 ! inositol metabolic process GO:0006020 20 14 0,000 0,06973636 0,10757453 ! aminoglycan catabolic process GO:0006026 18 14 0,000 0,06973636 0,10750243 ! vesicle targeting, to, from or within Golgi GO:0048199 18 14 0,000 0,06973636 0,10743042 ! retina development in camera-type eye GO:0060041 18 14 0,000 0,06973636 0,10735852 ! cardiac muscle contraction GO:0060048 23 14 0,000 0,06973636 0,10728671 ! gene silencing by RNA GO:0031047 20 14 0,000 0,06973636 0,10721499 ! response to cAMP GO:0051591 19 14 0,000 0,06973636 0,10714337 ! startle response GO:0001964 21 14 0,000 0,06973636 0,10707185 ! negative regulation of endothelial cell proliferation GO:0001937 29 14 0,000 0,06973636 0,10700042 ! negative regulation of gene expression, epigenetic GO:0045814 23 14 0,000 0,06973636 0,10692908 ! activation of MAPKK activity GO:0000186 21 14 0,000 0,06973636 0,10685784 ! regulation of defense response to virus GO:0050688 24 14 0,000 0,06973636 0,1067867 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 17 14 0,000 0,06973636 0,10671565 ! epidermis morphogenesis GO:0048730 29 14 0,000 0,06973636 0,1066447 ! glycine metabolic process GO:0006544 22 14 0,000 0,06973636 0,10657384 ! pituitary gland development GO:0021983 23 14 0,000 0,06973636 0,10650307 ! negative regulation of microtubule depolymerization GO:0007026 31 14 0,000 0,06973636 0,1064324 GO:0031114|regulation of microtubule depolymerization, ! lysosomal transport GO:0007041 20 14 0,000 0,06973636 0,10636182 ! regulation of heart rate GO:0002027 23 14 0,000 0,06973636 0,10629133 ! preassembly of GPI anchor in ER membrane GO:0016254 17 14 0,000 0,06973636 0,10622094 ! negative regulation of caspase activity GO:0043154 20 14 0,000 0,06973636 0,10615064 ! branching involved in ureteric bud morphogenesis GO:0001658 22 14 0,000 0,06973636 0,10608044 GO:0060675|ureteric bud morphogenesis, ! embryo implantation GO:0007566 27 14 0,000 0,06973636 0,10601033 ! purine nucleoside monophosphate metabolic process GO:0009126 21 14 0,000 0,06973636 0,10594031 GO:0009127|purine nucleoside monophosphate biosynthetic process, GO:0009168|purine ribonucleoside monophosphate biosynthetic process, GO:0009167|purine ribonucleoside monophosphate metabolic process, ! positive regulation of axonogenesis GO:0050772 19 14 0,000 0,06973636 0,10587038 ! positive regulation of biomineral formation GO:0070169 20 14 0,000 0,06973636 0,10580054 ! DNA unwinding during replication GO:0006268 21 14 0,000 0,06973636 0,1057308 ! T cell differentiation in the thymus GO:0033077 27 14 0,000 0,06973636 0,10566115 ! mRNA splice site selection GO:0006376 26 14 0,000 0,06973636 0,10559159 ! regulation of T-helper 2 type immune response GO:0002828 21 14 0,000 0,06973636 0,10552212 ! negative regulation of inflammatory response GO:0050728 16 14 0,000 0,06973636 0,10545274 ! negative regulation of blood coagulation GO:0030195 19 14 0,000 0,06973636 0,10538346 ! sphingolipid catabolic process GO:0030149 23 14 0,000 0,06973636 0,10531426 GO:0046466|membrane lipid catabolic process, ! water homeostasis GO:0030104 24 14 0,000 0,06973636 0,10524516 ! synaptic transmission, cholinergic GO:0007271 21 14 0,000 0,06973636 0,10517615 ! regulation of erythrocyte differentiation GO:0045646 27 14 0,000 0,06973636 0,10510722 ! muscle maintenance GO:0046716 19 14 0,000 0,06973636 0,10503839 ! C21-steroid hormone biosynthetic process GO:0006700 15 14 0,000 0,06973636 0,10496965 ! activation of NF-kappaB-inducing kinase activity GO:0007250 20 14 0,000 0,06973636 0,104901 ! regulation of ATPase activity GO:0043462 18 14 0,000 0,06973636 0,10483243 ! catecholamine biosynthetic process GO:0042423 23 14 0,000 0,06973636 0,10476396 ! cell killing GO:0001906 20 14 0,000 0,06973636 0,10469558 ! epithelial to mesenchymal transition GO:0001837 22 14 0,000 0,06973636 0,10462728 ! cilium assembly GO:0042384 20 14 0,000 0,06973636 0,10455908 ! peptide hormone secretion GO:0030072 23 14 0,000 0,06973636 0,10449096 ! positive regulation of MAP kinase activity GO:0043406 121 85 1,000 0,07110337 0,10646988 ! negative regulation of multicellular organismal process GO:0051241 133 85 1,000 0,07110337 0,10640061 ! regulation of cyclic nucleotide metabolic process GO:0030799 147 86 1,000 0,07255995 0,10850967 ! regulation of protein ubiquitination GO:0031396 19 15 0,000 0,07452934 0,11138237 ! positive regulation of cell size GO:0045793 20 15 0,000 0,07452934 0,11131005 ! metencephalon development GO:0022037 19 15 0,000 0,07452934 0,11123781 ! sulfur amino acid biosynthetic process GO:0000097 17 15 0,000 0,07452934 0,11116568 ! negative regulation of hormone secretion GO:0046888 20 15 0,000 0,07452934 0,11109363 ! negative regulation of cell cycle process GO:0010948 24 15 0,000 0,07452934 0,11102168 ! skin development GO:0043588 25 15 0,000 0,07452934 0,11094982 ! embryonic hindlimb morphogenesis GO:0035116 25 15 0,000 0,07452934 0,11087805 ! regulation of neurotransmitter secretion GO:0046928 26 15 0,000 0,07452934 0,11080638 ! regulation of excitatory postsynaptic membrane potential GO:0060079 25 15 0,000 0,07452934 0,1107348 ! bile acid metabolic process GO:0008206 22 15 0,000 0,07452934 0,11066331 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 21 15 0,000 0,07452934 0,11059192 ! regulation of muscle cell differentiation GO:0051147 24 15 0,000 0,07452934 0,11052061 ! adult walking behavior GO:0007628 25 15 0,000 0,07452934 0,1104494 ! isoprenoid biosynthetic process GO:0008299 21 15 0,000 0,07452934 0,11037828 ! positive regulation of proteolysis GO:0045862 19 15 0,000 0,07452934 0,11030725 ! regulation of survival gene product expression GO:0045884 20 15 0,000 0,07452934 0,11023632 ! cardiac muscle tissue development GO:0048738 23 15 0,000 0,07452934 0,11016547 ! pyrimidine ribonucleotide metabolic process GO:0009218 19 15 0,000 0,07452934 0,11009472 ! cerebral cortex development GO:0021987 29 15 0,000 0,07452934 0,11002405 ! response to osmotic stress GO:0006970 22 15 0,000 0,07452934 0,10995348 ! vesicle coating GO:0006901 25 15 0,000 0,07452934 0,109883 ! regulation of the force of heart contraction GO:0002026 21 15 0,000 0,07452934 0,1098126 ! DNA integration GO:0015074 22 15 0,000 0,07452934 0,1097423 ! peptide secretion GO:0002790 27 15 0,000 0,07452934 0,10967209 ! embryonic digit morphogenesis GO:0042733 18 15 0,000 0,07452934 0,10960196 ! regulation of vasodilation GO:0042312 24 15 0,000 0,07452934 0,10953193 ! regulation of T cell mediated immunity GO:0002709 26 15 0,000 0,07452934 0,10946199 ! DNA fragmentation involved in apoptosis GO:0006309 19 15 0,000 0,07452934 0,10939213 ! positive regulation of oxidoreductase activity GO:0051353 21 15 0,000 0,07452934 0,10932237 ! peptide biosynthetic process GO:0043043 19 15 0,000 0,07452934 0,10925269 ! biomineral formation GO:0031214 18 15 0,000 0,07452934 0,1091831 ! folic acid and derivative metabolic process GO:0006760 17 15 0,000 0,07452934 0,1091136 ! aspartate family amino acid biosynthetic process GO:0009067 16 15 0,000 0,07452934 0,10904419 ! dopamine metabolic process GO:0042417 30 15 0,000 0,07452934 0,10897487 ! organic cation transport GO:0015695 19 15 0,000 0,07452934 0,10890564 ! porphyrin biosynthetic process GO:0006779 22 15 0,000 0,07452934 0,10883649 GO:0033014|tetrapyrrole biosynthetic process, ! regulation of BMP signaling pathway GO:0030510 21 15 0,000 0,07452934 0,10876743 ! negative regulation of leukocyte proliferation GO:0070664 25 15 0,000 0,07452934 0,10869846 GO:0050672|negative regulation of lymphocyte proliferation, GO:0032945|negative regulation of mononuclear cell proliferation, ! defense response to virus GO:0051607 27 15 0,000 0,07452934 0,10862958 ! peptide hormone processing GO:0016486 19 15 0,000 0,07452934 0,10856078 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 33 15 0,000 0,07452934 0,10849207 ! anatomical structure homeostasis GO:0060249 136 88 1,000 0,07550202 0,10983848 ! carboxylic acid catabolic process GO:0046395 122 88 1,000 0,07550202 0,10976905 GO:0016054|organic acid catabolic process, ! establishment of RNA localization GO:0051236 128 88 1,000 0,07550202 0,10969971 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! reproductive developmental process GO:0003006 127 89 1,000 0,07698724 0,11178702 ! regulation of nucleotide metabolic process GO:0006140 150 89 1,000 0,07698724 0,1117165 ! protein modification by small protein conjugation GO:0032446 140 90 1,000 0,07848173 0,11381336 ! protein secretion GO:0009306 27 16 0,000 0,07929789 0,11492448 ! regulation of glucose metabolic process GO:0010906 22 16 0,000 0,07929789 0,11485211 ! hormone secretion GO:0046879 25 16 0,000 0,07929789 0,11477983 ! bone remodeling GO:0046849 24 16 0,000 0,07929789 0,11470764 ! endothelial cell migration GO:0043542 22 16 0,000 0,07929789 0,11463554 ! protein amino acid deacetylation GO:0006476 20 16 0,000 0,07929789 0,11456354 ! positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 20 16 0,000 0,07929789 0,11449162 ! positive regulation of receptor-mediated endocytosis GO:0048260 18 16 0,000 0,07929789 0,11441979 ! glial cell development GO:0021782 24 16 0,000 0,07929789 0,11434806 ! cellular response to hydrogen peroxide GO:0070301 21 16 0,000 0,07929789 0,11427641 GO:0042744|hydrogen peroxide catabolic process, ! mitotic chromosome condensation GO:0007076 25 16 0,000 0,07929789 0,11420485 ! protein polyubiquitination GO:0000209 26 16 0,000 0,07929789 0,11413339 ! complement activation, alternative pathway GO:0006957 16 16 0,000 0,07929789 0,11406201 ! pyrimidine ribonucleoside metabolic process GO:0046131 20 16 0,000 0,07929789 0,11399072 ! fructose metabolic process GO:0006000 20 16 0,000 0,07929789 0,11391952 ! regulation of protein binding GO:0043393 27 16 0,000 0,07929789 0,11384841 ! regulation of dephosphorylation GO:0035303 33 16 0,000 0,07929789 0,11377739 ! NLS-bearing substrate import into nucleus GO:0006607 33 16 0,000 0,07929789 0,11370645 ! protein export from nucleus GO:0006611 24 16 0,000 0,07929789 0,11363561 ! negative regulation of immune response GO:0050777 28 16 0,000 0,07929789 0,11356485 ! nucleotide-excision repair, DNA gap filling GO:0006297 20 16 0,000 0,07929789 0,11349418 ! DNA replication initiation GO:0006270 25 16 0,000 0,07929789 0,1134236 ! regulation of steroid metabolic process GO:0019218 21 16 0,000 0,07929789 0,11335311 ! ribosomal small subunit biogenesis GO:0042274 18 16 0,000 0,07929789 0,1132827 ! diencephalon development GO:0021536 25 16 0,000 0,07929789 0,11321238 ! neural crest cell migration GO:0001755 24 16 0,000 0,07929789 0,11314215 ! G1 phase GO:0051318 27 16 0,000 0,07929789 0,11307201 ! neutrophil chemotaxis GO:0030593 21 16 0,000 0,07929789 0,11300195 ! protein localization in mitochondrion GO:0070585 22 16 0,000 0,07929789 0,11293198 GO:0006626|protein targeting to mitochondrion, ! steroid catabolic process GO:0006706 22 16 0,000 0,07929789 0,1128621 ! branched chain family amino acid metabolic process GO:0009081 24 16 0,000 0,07929789 0,1127923 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 21 16 0,000 0,07929789 0,11272259 ! regulation of generation of precursor metabolites and energy GO:0043467 26 16 0,000 0,07929789 0,11265296 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 22 16 0,000 0,07929789 0,11258343 ! aromatic compound biosynthetic process GO:0019438 18 16 0,000 0,07929789 0,11251397 ! sperm-egg recognition GO:0035036 16 16 0,000 0,07929789 0,11244461 GO:0007339|binding of sperm to zona pellucida, ! somatic recombination of immunoglobulin gene segments GO:0016447 26 16 0,000 0,07929789 0,11237532 ! antigen receptor-mediated signaling pathway GO:0050851 26 16 0,000 0,07929789 0,11230613 ! inner ear receptor cell differentiation GO:0060113 30 16 0,000 0,07929789 0,11223702 ! negative regulation of translation GO:0017148 22 16 0,000 0,07929789 0,11216799 ! response to virus GO:0009615 122 91 1,000 0,07998538 0,11307091 ! RNA localization GO:0006403 135 91 1,000 0,07998538 0,11300145 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 130 92 1,000 0,08149803 0,11506782 ! cell fate commitment GO:0045165 141 92 1,000 0,08149803 0,11499722 ! polysaccharide metabolic process GO:0005976 129 93 1,000 0,08301957 0,11707236 ! oligosaccharide metabolic process GO:0009311 26 17 0,000 0,08404215 0,11844175 ! positive regulation of cell killing GO:0031343 24 17 0,000 0,08404215 0,11836922 ! negative regulation of defense response GO:0031348 19 17 0,000 0,08404215 0,11829678 ! positive regulation of hormone secretion GO:0046887 24 17 0,000 0,08404215 0,11822443 ! glycerol metabolic process GO:0006071 20 17 0,000 0,08404215 0,11815216 ! 2'-deoxyribonucleotide metabolic process GO:0009394 22 17 0,000 0,08404215 0,11807999 GO:0019692|deoxyribose phosphate metabolic process, ! zinc ion transport GO:0006829 20 17 0,000 0,08404215 0,1180079 ! phosphatidylcholine metabolic process GO:0046470 22 17 0,000 0,08404215 0,1179359 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 17 0,000 0,08404215 0,11786399 ! intra-Golgi vesicle-mediated transport GO:0006891 26 17 0,000 0,08404215 0,11779216 ! glycosaminoglycan biosynthetic process GO:0006024 26 17 0,000 0,08404215 0,11772043 ! memory GO:0007613 25 17 0,000 0,08404215 0,11764878 ! keratinization GO:0031424 17 17 0,000 0,08404215 0,11757721 ! negative regulation of ion transport GO:0043271 20 17 0,000 0,08404215 0,11750574 ! negative regulation of peptidase activity GO:0010466 23 17 0,000 0,08404215 0,11743435 ! retinoid metabolic process GO:0001523 22 17 0,000 0,08404215 0,11736305 GO:0016101|diterpenoid metabolic process, ! regulation of viral genome replication GO:0045069 24 17 0,000 0,08404215 0,11729183 ! inactivation of MAPK activity GO:0000188 27 17 0,000 0,08404215 0,1172207 ! regulation of striated muscle contraction GO:0006942 20 17 0,000 0,08404215 0,11714966 ! DNA duplex unwinding GO:0032508 25 17 0,000 0,08404215 0,1170787 GO:0032392|DNA geometric change, ! vacuolar transport GO:0007034 24 17 0,000 0,08404215 0,11700783 ! cell-substrate junction assembly GO:0007044 39 17 0,000 0,08404215 0,11693705 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 17 0,000 0,08404215 0,11686635 ! cellular macromolecular complex disassembly GO:0034623 29 17 0,000 0,08404215 0,11679573 ! actin polymerization or depolymerization GO:0008154 31 17 0,000 0,08404215 0,11672521 ! membrane budding GO:0006900 29 17 0,000 0,08404215 0,11665476 ! heme metabolic process GO:0042168 27 17 0,000 0,08404215 0,1165844 ! actin filament bundle formation GO:0051017 26 17 0,000 0,08404215 0,11651413 ! neuromuscular junction development GO:0007528 23 17 0,000 0,08404215 0,11644394 ! body fluid secretion GO:0007589 27 17 0,000 0,08404215 0,11637384 ! stem cell differentiation GO:0048863 36 17 0,000 0,08404215 0,11630382 ! nucleobase metabolic process GO:0009112 31 17 0,000 0,08404215 0,11623388 ! ventricular cardiac muscle morphogenesis GO:0055010 23 17 0,000 0,08404215 0,11616403 ! behavioral interaction between organisms GO:0051705 25 17 0,000 0,08404215 0,11609426 ! sensory perception of pain GO:0019233 23 17 0,000 0,08404215 0,11602457 ! regulation of immunoglobulin mediated immune response GO:0002889 25 17 0,000 0,08404215 0,11595497 GO:0002712|regulation of B cell mediated immunity, ! long-chain fatty acid transport GO:0015909 24 17 0,000 0,08404215 0,11588546 ! synaptogenesis GO:0007416 24 17 0,000 0,08404215 0,11581602 ! sphingolipid biosynthetic process GO:0030148 21 17 0,000 0,08404215 0,11574667 GO:0046467|membrane lipid biosynthetic process, ! vitamin A metabolic process GO:0006776 22 17 0,000 0,08404215 0,1156774 ! cell-cell junction organization GO:0045216 25 17 0,000 0,08404215 0,11560822 ! regulation of immunoglobulin production GO:0002637 25 17 0,000 0,08404215 0,11553912 ! proximal/distal pattern formation GO:0009954 25 17 0,000 0,08404215 0,1154701 ! positive regulation of synaptic transmission GO:0050806 24 17 0,000 0,08404215 0,11540116 ! negative regulation of coagulation GO:0050819 23 17 0,000 0,08404215 0,1153323 ! electron transport chain GO:0022900 123 94 1,000 0,08454987 0,11595986 ! regulation of response to external stimulus GO:0032101 139 96 1,000 0,08763621 0,12012114 ! nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015931 138 96 1,000 0,08763621 0,1200496 ! regulation of cellular component biogenesis GO:0044087 158 96 1,000 0,08763621 0,11997814 ! protein modification by small protein conjugation or removal GO:0070647 148 96 1,000 0,08763621 0,11990677 ! positive regulation of DNA replication GO:0045740 29 18 0,000 0,08876223 0,12137522 ! positive regulation of translation GO:0045727 28 18 0,000 0,08876223 0,12130311 ! positive regulation of anti-apoptosis GO:0045768 29 18 0,000 0,08876223 0,12123107 ! positive regulation of angiogenesis GO:0045766 35 18 0,000 0,08876223 0,12115913 ! post-Golgi vesicle-mediated transport GO:0006892 35 18 0,000 0,08876223 0,12108726 ! protein amino acid ADP-ribosylation GO:0006471 27 18 0,000 0,08876223 0,12101549 ! cAMP metabolic process GO:0046058 33 18 0,000 0,08876223 0,12094379 ! aminoglycan biosynthetic process GO:0006023 27 18 0,000 0,08876223 0,12087219 ! transcription from RNA polymerase III promoter GO:0006383 32 18 0,000 0,08876223 0,12080067 ! gamma-aminobutyric acid signaling pathway GO:0007214 20 18 0,000 0,08876223 0,12072923 ! axis specification GO:0009798 26 18 0,000 0,08876223 0,12065788 ! regulation of systemic arterial blood pressure by hormone GO:0001990 26 18 0,000 0,08876223 0,12058661 GO:0050886|endocrine process, ! mechanoreceptor differentiation GO:0042490 32 18 0,000 0,08876223 0,12051542 ! pancreas development GO:0031016 26 18 0,000 0,08876223 0,12044432 ! response to carbohydrate stimulus GO:0009743 24 18 0,000 0,08876223 0,12037331 ! glutamine metabolic process GO:0006541 23 18 0,000 0,08876223 0,12030237 ! central nervous system neuron development GO:0021954 30 18 0,000 0,08876223 0,12023152 ! positive regulation of cytoskeleton organization GO:0051495 33 18 0,000 0,08876223 0,12016076 ! fucose metabolic process GO:0006004 26 18 0,000 0,08876223 0,12009007 ! response to fungus GO:0009620 19 18 0,000 0,08876223 0,12001947 ! peptide cross-linking GO:0018149 31 18 0,000 0,08876223 0,11994896 ! heart process GO:0003015 27 18 0,000 0,08876223 0,11987852 GO:0060047|heart contraction, ! prostaglandin metabolic process GO:0006693 31 18 0,000 0,08876223 0,11980817 GO:0006692|prostanoid metabolic process, ! positive regulation of phosphoinositide 3-kinase cascade GO:0014068 24 18 0,000 0,08876223 0,1197379 ! visual learning GO:0008542 35 18 0,000 0,08876223 0,11966772 ! synaptic vesicle transport GO:0048489 33 18 0,000 0,08876223 0,11959761 ! detection of chemical stimulus GO:0009593 26 18 0,000 0,08876223 0,11952759 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 25 18 0,000 0,08876223 0,11945765 ! regulation of cytokine secretion GO:0050707 26 18 0,000 0,08876223 0,11938779 ! vitamin transport GO:0051180 24 18 0,000 0,08876223 0,11931802 ! hormone transport GO:0009914 27 18 0,000 0,08876223 0,11924832 ! activation of JUN kinase activity GO:0007257 23 18 0,000 0,08876223 0,11917871 ! terpenoid metabolic process GO:0006721 24 18 0,000 0,08876223 0,11910917 ! positive regulation of transmission of nerve impulse GO:0051971 25 18 0,000 0,08876223 0,11903972 ! cell-cell recognition GO:0009988 20 18 0,000 0,08876223 0,11897035 ! purine nucleotide catabolic process GO:0006195 26 18 0,000 0,08876223 0,11890106 ! estrogen receptor signaling pathway GO:0030520 30 18 0,000 0,08876223 0,11883185 ! regulation of glucose import GO:0046324 21 18 0,000 0,08876223 0,11876273 GO:0010827|regulation of glucose transport, ! gut development GO:0048565 26 18 0,000 0,08876223 0,11869368 ! regulation of mitotic metaphase/anaphase transition GO:0030071 29 18 0,000 0,08876223 0,11862471 ! negative regulation of T cell activation GO:0050868 25 18 0,000 0,08876223 0,11855582 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 97 1,000 0,089192 0,11906071 ! negative regulation of cellular protein metabolic process GO:0032269 163 99 1,000 0,09232822 0,1231757 ! protein import into nucleus, docking GO:0000059 30 19 0,000 0,09345825 0,12461101 ! positive regulation of fibroblast proliferation GO:0048146 27 19 0,000 0,09345825 0,12453881 ! positive regulation of ossification GO:0045778 30 19 0,000 0,09345825 0,1244667 ! pteridine and derivative metabolic process GO:0042558 23 19 0,000 0,09345825 0,12439467 ! regulation of neuronal synaptic plasticity GO:0048168 36 19 0,000 0,09345825 0,12432272 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 27 19 0,000 0,09345825 0,12425086 ! regulation of carbohydrate metabolic process GO:0006109 28 19 0,000 0,09345825 0,12417908 GO:0010675|regulation of cellular carbohydrate metabolic process, ! regulation of postsynaptic membrane potential GO:0060078 30 19 0,000 0,09345825 0,12410738 ! C21-steroid hormone metabolic process GO:0008207 23 19 0,000 0,09345825 0,12403577 ! regeneration GO:0031099 32 19 0,000 0,09345825 0,12396424 ! response to alkaloid GO:0043279 32 19 0,000 0,09345825 0,12389279 ! sensory perception of taste GO:0050909 23 19 0,000 0,09345825 0,12382142 ! positive regulation of epithelial cell proliferation GO:0050679 37 19 0,000 0,09345825 0,12375014 ! smooth muscle contraction GO:0006939 36 19 0,000 0,09345825 0,12367893 ! peroxisome organization GO:0007031 29 19 0,000 0,09345825 0,12360781 ! digestive system process GO:0022600 30 19 0,000 0,09345825 0,12353677 ! cellular response to reactive oxygen species GO:0034614 27 19 0,000 0,09345825 0,12346582 ! polysaccharide catabolic process GO:0000272 23 19 0,000 0,09345825 0,12339494 ! D-ribose metabolic process GO:0006014 25 19 0,000 0,09345825 0,12332415 ! vesicle docking during exocytosis GO:0006904 24 19 0,000 0,09345825 0,12325343 ! cell structure disassembly during apoptosis GO:0006921 24 19 0,000 0,09345825 0,1231828 ! apoptotic nuclear changes GO:0030262 24 19 0,000 0,09345825 0,12311225 ! sex determination GO:0007530 29 19 0,000 0,09345825 0,12304178 ! response to lipopolysaccharide GO:0032496 26 19 0,000 0,09345825 0,12297139 ! cytolysis GO:0019835 20 19 0,000 0,09345825 0,12290108 ! renal system process GO:0003014 35 19 0,000 0,09345825 0,12283085 ! vasodilation GO:0042311 33 19 0,000 0,09345825 0,1227607 ! regulation of phosphoinositide 3-kinase cascade GO:0014066 25 19 0,000 0,09345825 0,12269063 ! regulation of fatty acid metabolic process GO:0019217 28 19 0,000 0,09345825 0,12262064 ! regulation of interleukin-6 production GO:0032675 22 19 0,000 0,09345825 0,12255073 ! positive regulation of neurological system process GO:0031646 28 19 0,000 0,09345825 0,1224809 ! sarcomere organization GO:0045214 23 19 0,000 0,09345825 0,12241115 ! positive regulation of myeloid cell differentiation GO:0045639 44 19 0,000 0,09345825 0,12234148 ! negative regulation of myeloid cell differentiation GO:0045638 26 19 0,000 0,09345825 0,12227189 ! leukotriene biosynthetic process GO:0019370 26 19 0,000 0,09345825 0,12220238 GO:0043450|alkene biosynthetic process, ! somatic diversification of immunoglobulins GO:0016445 29 19 0,000 0,09345825 0,12213295 ! embryonic organ morphogenesis GO:0048562 23 19 0,000 0,09345825 0,12206359 ! pyrimidine nucleotide biosynthetic process GO:0006221 24 19 0,000 0,09345825 0,12199432 ! regulation of translation GO:0006417 151 100 1,000 0,09390839 0,12251236 ! homophilic cell adhesion GO:0007156 149 100 1,000 0,09390839 0,12244291 ! cyclic-nucleotide-mediated signaling GO:0019935 146 100 1,000 0,09390839 0,12237354 ! cellular aldehyde metabolic process GO:0006081 29 20 0,000 0,09813035 0,12780283 ! iron ion transport GO:0006826 37 20 0,000 0,09813035 0,1277305 ! protein amino acid O-linked glycosylation GO:0006493 29 20 0,000 0,09813035 0,12765826 ! glucosamine metabolic process GO:0006041 25 20 0,000 0,09813035 0,12758609 GO:0006044|N-acetylglucosamine metabolic process, ! regulation of receptor-mediated endocytosis GO:0048259 23 20 0,000 0,09813035 0,12751401 ! regulation of neurotransmitter transport GO:0051588 35 20 0,000 0,09813035 0,12744201 ! spinal cord development GO:0021510 31 20 0,000 0,09813035 0,12737009 ! response to ethanol GO:0045471 37 20 0,000 0,09813035 0,12729825 ! multicellular organismal response to stress GO:0033555 32 20 0,000 0,09813035 0,12722649 ! regulation of nitric oxide biosynthetic process GO:0045428 35 20 0,000 0,09813035 0,12715482 ! central nervous system neuron differentiation GO:0021953 33 20 0,000 0,09813035 0,12708322 ! neurotransmitter metabolic process GO:0042133 30 20 0,000 0,09813035 0,1270117 ! chromosome condensation GO:0030261 31 20 0,000 0,09813035 0,12694027 ! fatty acid beta-oxidation GO:0006635 31 20 0,000 0,09813035 0,12686891 ! regulation of myeloid leukocyte differentiation GO:0002761 34 20 0,000 0,09813035 0,12679764 ! determination of left/right symmetry GO:0007368 23 20 0,000 0,09813035 0,12672645 ! regulation of ARF GTPase activity GO:0032312 31 20 0,000 0,09813035 0,12665533 ! DNA modification GO:0006304 28 20 0,000 0,09813035 0,1265843 ! collagen fibril organization GO:0030199 45 20 0,000 0,09813035 0,12651334 ! positive regulation of inflammatory response GO:0050729 30 20 0,000 0,09813035 0,12644246 ! positive regulation of osteoblast differentiation GO:0045669 33 20 0,000 0,09813035 0,12637167 ! neuromuscular process controlling balance GO:0050885 48 20 0,000 0,09813035 0,12630095 ! positive regulation of B cell activation GO:0050871 31 20 0,000 0,09813035 0,12623031 ! collagen catabolic process GO:0030574 25 20 0,000 0,09813035 0,12615975 ! regulation of leukocyte mediated cytotoxicity GO:0001910 32 20 0,000 0,09813035 0,12608927 ! camera-type eye morphogenesis GO:0048593 34 20 0,000 0,09813035 0,12601887 ! alditol metabolic process GO:0019400 24 20 0,000 0,09813035 0,12594855 ! actin filament-based movement GO:0030048 34 20 0,000 0,09813035 0,1258783 ! positive regulation of tyrosine phosphorylation of Stat5 protein GO:0042523 26 21 0,000 0,10277863 0,13176747 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 33 21 0,000 0,10277863 0,13169406 GO:0016444|somatic cell DNA recombination, ! regulation of cell killing GO:0031341 34 21 0,000 0,10277863 0,13162074 ! myeloid leukocyte differentiation GO:0002573 33 21 0,000 0,10277863 0,13154749 ! sulfur amino acid metabolic process GO:0000096 24 21 0,000 0,10277863 0,13147433 ! determination of bilateral symmetry GO:0009855 25 21 0,000 0,10277863 0,13140125 GO:0009799|determination of symmetry, ! gluconeogenesis GO:0006094 25 21 0,000 0,10277863 0,13132825 ! DNA catabolic process, endonucleolytic GO:0000737 26 21 0,000 0,10277863 0,13125533 ! positive regulation of bone remodeling GO:0046852 33 21 0,000 0,10277863 0,13118249 GO:0034105|positive regulation of tissue remodeling, ! nucleotide-excision repair, DNA damage removal GO:0000718 26 21 0,000 0,10277863 0,13110973 ! cellular polysaccharide biosynthetic process GO:0033692 26 21 0,000 0,10277863 0,13103705 ! vesicle docking GO:0048278 27 21 0,000 0,10277863 0,13096446 ! phototransduction GO:0007602 25 21 0,000 0,10277863 0,13089194 ! visual behavior GO:0007632 39 21 0,000 0,10277863 0,1308195 ! regulation of DNA recombination GO:0000018 40 21 0,000 0,10277863 0,13074715 ! ovarian follicle development GO:0001541 30 21 0,000 0,10277863 0,13067487 ! activation of pro-apoptotic gene products GO:0008633 36 21 0,000 0,10277863 0,13060268 ! deoxyribonucleotide metabolic process GO:0009262 27 21 0,000 0,10277863 0,13053056 ! purine ribonucleoside metabolic process GO:0046128 28 21 0,000 0,10277863 0,13045852 GO:0042278|purine nucleoside metabolic process, ! autophagy GO:0006914 28 21 0,000 0,10277863 0,13038657 ! regulation of insulin secretion GO:0050796 26 21 0,000 0,10277863 0,13031469 ! cardiac muscle tissue morphogenesis GO:0055008 27 21 0,000 0,10277863 0,13024289 GO:0060415|muscle tissue morphogenesis, ! cholesterol biosynthetic process GO:0006695 29 21 0,000 0,10277863 0,13017117 ! leukotriene metabolic process GO:0006691 28 21 0,000 0,10277863 0,13009953 ! regulation of vasoconstriction GO:0019229 31 21 0,000 0,10277863 0,13002797 ! glycosphingolipid metabolic process GO:0006687 33 21 0,000 0,10277863 0,12995648 ! fatty acid transport GO:0015908 30 21 0,000 0,10277863 0,12988508 ! immunoglobulin production GO:0002377 33 21 0,000 0,10277863 0,12981375 GO:0002440|production of molecular mediator of immune response, ! platelet activation GO:0030168 28 21 0,000 0,10277863 0,1297425 ! negative regulation of Wnt receptor signaling pathway GO:0030178 31 21 0,000 0,10277863 0,12967134 ! positive regulation of protein secretion GO:0050714 26 21 0,000 0,10277863 0,12960024 ! positive regulation of adaptive immune response GO:0002821 31 21 0,000 0,10277863 0,12952923 ! response to glucocorticoid stimulus GO:0051384 33 21 0,000 0,10277863 0,12945829 ! regulation of bone mineralization GO:0030500 29 21 0,000 0,10277863 0,12938744 ! nerve-nerve synaptic transmission GO:0007270 36 21 0,000 0,10277863 0,12931665 ! glutamine family amino acid catabolic process GO:0009065 30 21 0,000 0,10277863 0,12924595 ! porphyrin metabolic process GO:0006778 35 21 0,000 0,10277863 0,12917532 GO:0033013|tetrapyrrole metabolic process, ! negative regulation of cytokine production GO:0001818 31 21 0,000 0,10277863 0,12910478 ! pyrimidine nucleoside metabolic process GO:0006213 26 21 0,000 0,10277863 0,1290343 ! acetyl-CoA catabolic process GO:0046356 31 21 0,000 0,10277863 0,12896391 GO:0006099|tricarboxylic acid cycle, ! regulation of multi-organism process GO:0043900 32 21 0,000 0,10277863 0,12889359 ! regulation of tyrosine phosphorylation of Stat5 protein GO:0042522 31 22 0,000 0,10740322 0,13461983 ! regulation of anti-apoptosis GO:0045767 36 22 0,000 0,10740322 0,13454651 ! regulation of transmembrane transport GO:0034762 30 22 0,000 0,10740322 0,13447327 ! spliceosomal snRNP biogenesis GO:0000387 28 22 0,000 0,10740322 0,13440011 ! leukocyte adhesion GO:0007159 38 22 0,000 0,10740322 0,13432702 ! molting cycle process GO:0022404 40 22 0,000 0,10740322 0,13425402 GO:0022405|hair cycle process, GO:0001942|hair follicle development, GO:0042633|hair cycle, GO:0042303|molting cycle, ! glutamate signaling pathway GO:0007215 34 22 0,000 0,10740322 0,13418109 ! macromolecular complex disassembly GO:0032984 38 22 0,000 0,10740322 0,13410825 ! odontogenesis of dentine-containing tooth GO:0042475 37 22 0,000 0,10740322 0,13403548 ! regulation of cell-matrix adhesion GO:0001952 51 22 0,000 0,10740322 0,1339628 GO:0010810|regulation of cell-substrate adhesion, ! immune response-activating cell surface receptor signaling pathway GO:0002429 32 22 0,000 0,10740322 0,13389019 GO:0002768|immune response-regulating cell surface receptor signaling pathway, ! regulation of smooth muscle contraction GO:0006940 36 22 0,000 0,10740322 0,13381766 ! lysosome organization GO:0007040 37 22 0,000 0,10740322 0,13374521 ! ureteric bud development GO:0001657 32 22 0,000 0,10740322 0,13367283 ! coenzyme catabolic process GO:0009109 33 22 0,000 0,10740322 0,13360054 ! regulation of tumor necrosis factor production GO:0032680 28 22 0,000 0,10740322 0,13352832 ! membrane depolarization GO:0051899 35 22 0,000 0,10740322 0,13345618 ! proteoglycan biosynthetic process GO:0030166 32 22 0,000 0,10740322 0,13338412 ! leukocyte homeostasis GO:0001776 33 22 0,000 0,10740322 0,13331214 ! regulation of blood coagulation GO:0030193 34 22 0,000 0,10740322 0,13324023 ! cellular alkene metabolic process GO:0043449 29 22 0,000 0,10740322 0,13316841 ! aspartate family amino acid metabolic process GO:0009066 24 22 0,000 0,10740322 0,13309666 ! positive regulation of JUN kinase activity GO:0043507 28 22 0,000 0,10740322 0,13302498 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 28 23 0,000 0,11200423 0,13864894 ! neuron fate commitment GO:0048663 32 23 0,000 0,11200423 0,13857436 ! embryonic pattern specification GO:0009880 31 23 0,000 0,11200423 0,13849985 ! positive regulation of cell adhesion GO:0045785 37 23 0,000 0,11200423 0,13842543 ! myelination GO:0042552 35 23 0,000 0,11200423 0,13835109 ! acetyl-CoA metabolic process GO:0006084 33 23 0,000 0,11200423 0,13827683 ! cellular iron ion homeostasis GO:0006879 37 23 0,000 0,11200423 0,13820264 ! vesicle targeting GO:0006903 32 23 0,000 0,11200423 0,13812854 ! response to corticosteroid stimulus GO:0031960 36 23 0,000 0,11200423 0,13805452 ! osteoblast differentiation GO:0001649 40 23 0,000 0,11200423 0,13798057 ! regulation of viral reproduction GO:0050792 32 23 0,000 0,11200423 0,13790671 ! hydrogen peroxide metabolic process GO:0042743 30 23 0,000 0,11200423 0,13783292 ! interaction with host GO:0051701 37 23 0,000 0,11200423 0,13775921 ! lymphocyte proliferation GO:0046651 36 23 0,000 0,11200423 0,13768558 ! regulation of biomineral formation GO:0070167 31 23 0,000 0,11200423 0,13761203 ! cellular response to oxidative stress GO:0034599 33 23 0,000 0,11200423 0,13753856 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 36 23 0,000 0,11200423 0,13746517 ! ribonucleoside monophosphate metabolic process GO:0009161 35 23 0,000 0,11200423 0,13739186 GO:0009156|ribonucleoside monophosphate biosynthetic process, ! glycolipid metabolic process GO:0006664 36 23 0,000 0,11200423 0,13731862 ! cell fate determination GO:0001709 45 23 0,000 0,11200423 0,13724546 ! pentose metabolic process GO:0019321 31 23 0,000 0,11200423 0,13717238 ! regulation of response to biotic stimulus GO:0002831 35 23 0,000 0,11200423 0,13709938 ! spermatid development GO:0007286 33 23 0,000 0,11200423 0,13702645 ! group transfer coenzyme metabolic process GO:0006752 28 23 0,000 0,11200423 0,1369536 ! fat-soluble vitamin metabolic process GO:0006775 28 23 0,000 0,11200423 0,13688083 ! ethanolamine and derivative metabolic process GO:0042439 33 23 0,000 0,11200423 0,13680814 ! somatic diversification of immune receptors GO:0002200 35 23 0,000 0,11200423 0,13673552 ! telomere organization GO:0032200 32 23 0,000 0,11200423 0,13666299 GO:0000723|telomere maintenance, ! response to molecule of bacterial origin GO:0002237 30 23 0,000 0,11200423 0,13659052 ! regulation of amine transport GO:0051952 38 23 0,000 0,11200423 0,13651814 ! liver development GO:0001889 40 23 0,000 0,11200423 0,13644583 ! positive regulation of cell projection organization GO:0031346 39 24 0,000 0,11658179 0,14194712 ! regulation of cellular catabolic process GO:0031329 36 24 0,000 0,11658179 0,14187202 ! initiation of viral infection GO:0019059 42 24 0,000 0,11658179 0,14179699 ! regulation of interferon-gamma production GO:0032649 30 24 0,000 0,11658179 0,14172205 ! pyruvate metabolic process GO:0006090 29 24 0,000 0,11658179 0,14164718 ! superoxide metabolic process GO:0006801 32 24 0,000 0,11658179 0,1415724 ! detection of light stimulus involved in sensory perception GO:0050962 28 24 0,000 0,11658179 0,14149769 GO:0050908|detection of light stimulus involved in visual perception, GO:0009584|detection of visible light, ! fat cell differentiation GO:0045444 37 24 0,000 0,11658179 0,14142306 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 32 24 0,000 0,11658179 0,14134851 ! sperm motility GO:0030317 27 24 0,000 0,11658179 0,14127403 ! vacuole organization GO:0007033 39 24 0,000 0,11658179 0,14119964 ! neural crest cell development GO:0014032 39 24 0,000 0,11658179 0,14112532 GO:0014033|neural crest cell differentiation, ! response to toxin GO:0009636 38 24 0,000 0,11658179 0,14105109 ! positive regulation of leukocyte mediated immunity GO:0002705 33 24 0,000 0,11658179 0,14097693 GO:0002708|positive regulation of lymphocyte mediated immunity, ! fibroblast growth factor receptor signaling pathway GO:0008543 39 24 0,000 0,11658179 0,14090285 ! regulation of oxidoreductase activity GO:0051341 39 24 0,000 0,11658179 0,14082884 ! glutathione metabolic process GO:0006749 29 24 0,000 0,11658179 0,14075492 ! regulation of osteoblast differentiation GO:0045667 37 24 0,000 0,11658179 0,14068107 ! neurotransmitter secretion GO:0007269 32 24 0,000 0,11658179 0,1406073 ! regulation of JUN kinase activity GO:0043506 34 24 0,000 0,11658179 0,1405336 ! amino sugar metabolic process GO:0006040 31 25 0,000 0,12113601 0,145947 ! protein amino acid alkylation GO:0008213 39 25 0,000 0,12113601 0,14587059 GO:0006479|protein amino acid methylation, ! calcium-dependent cell-cell adhesion GO:0016339 30 25 0,000 0,12113601 0,14579426 ! cellular carbohydrate biosynthetic process GO:0034637 30 25 0,000 0,12113601 0,14571801 ! regulation of cellular ketone metabolic process GO:0010565 34 25 0,000 0,12113601 0,14564184 ! peptide transport GO:0015833 43 25 0,000 0,12113601 0,14556574 ! male gonad development GO:0008584 33 25 0,000 0,12113601 0,14548973 ! iron ion homeostasis GO:0055072 39 25 0,000 0,12113601 0,14541379 ! regulation of peptide secretion GO:0002791 34 25 0,000 0,12113601 0,14533794 ! cyclic nucleotide biosynthetic process GO:0009190 36 25 0,000 0,12113601 0,14526216 ! regulation of chromosome organization GO:0033044 35 25 0,000 0,12113601 0,14518647 ! phospholipid transport GO:0015914 35 25 0,000 0,12113601 0,14511085 ! response to estradiol stimulus GO:0032355 34 25 0,000 0,12113601 0,14503531 ! positive regulation of MAPKKK cascade GO:0043410 36 25 0,000 0,12113601 0,14495985 ! detection of light stimulus GO:0009583 30 25 0,000 0,12113601 0,14488447 ! positive regulation of nuclear division GO:0051785 39 25 0,000 0,12113601 0,14480916 GO:0045840|positive regulation of mitosis, ! leukocyte proliferation GO:0070661 39 25 0,000 0,12113601 0,14473394 GO:0032943|mononuclear cell proliferation, ! negative regulation of lymphocyte activation GO:0051250 37 25 0,000 0,12113601 0,14465879 ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 29 26 0,000 0,12566702 0,14999177 ! translational initiation GO:0006413 43 26 0,000 0,12566702 0,14991397 ! circadian rhythm GO:0007623 42 26 0,000 0,12566702 0,14983626 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 34 26 0,000 0,12566702 0,14975862 ! post-embryonic development GO:0009791 42 26 0,000 0,12566702 0,14968107 ! negative regulation of protein modification process GO:0031400 50 26 0,000 0,12566702 0,14960359 ! positive regulation of innate immune response GO:0045089 31 26 0,000 0,12566702 0,1495262 ! multicellular organismal catabolic process GO:0044243 32 26 0,000 0,12566702 0,14944888 ! negative regulation of protein kinase cascade GO:0010741 51 26 0,000 0,12566702 0,14937165 ! spermatid differentiation GO:0048515 36 26 0,000 0,12566702 0,1492945 ! regulation of coagulation GO:0050818 39 26 0,000 0,12566702 0,14921742 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 27 0,000 0,13017492 0,15449036 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling, ! proteoglycan metabolic process GO:0006029 41 27 0,000 0,13017492 0,15441069 ! membrane docking GO:0022406 39 27 0,000 0,13017492 0,15433109 ! inner ear morphogenesis GO:0042472 35 27 0,000 0,13017492 0,15425158 ! catechol metabolic process GO:0009712 43 27 0,000 0,13017492 0,15417215 GO:0006584|catecholamine metabolic process, GO:0034311|diol metabolic process, ! GPI anchor biosynthetic process GO:0006506 37 27 0,000 0,13017492 0,15409281 ! acute-phase response GO:0006953 42 27 0,000 0,13017492 0,15401354 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 49 27 0,000 0,13017492 0,15393436 ! myofibril assembly GO:0030239 36 27 0,000 0,13017492 0,15385525 GO:0055002|striated muscle cell development, ! respiratory gaseous exchange GO:0007585 47 27 0,000 0,13017492 0,15377623 ! regulation of production of molecular mediator of immune response GO:0002700 40 27 0,000 0,13017492 0,15369729 ! natural killer cell activation GO:0030101 35 27 0,000 0,13017492 0,15361843 ! lipid oxidation GO:0034440 38 27 0,000 0,13017492 0,15353965 GO:0019395|fatty acid oxidation, ! cofactor catabolic process GO:0051187 45 27 0,000 0,13017492 0,15346095 ! negative regulation of leukocyte activation GO:0002695 39 27 0,000 0,13017492 0,15338234 ! serine family amino acid metabolic process GO:0009069 37 27 0,000 0,13017492 0,1533038 ! negative regulation of neuron apoptosis GO:0043524 42 27 0,000 0,13017492 0,15322534 ! gene silencing GO:0016458 41 27 0,000 0,13017492 0,15314697 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 39 28 0,000 0,13465984 0,15834235 ! mRNA export from nucleus GO:0006406 39 28 0,000 0,13465984 0,15826144 ! phenol metabolic process GO:0018958 44 28 0,000 0,13465984 0,15818061 ! icosanoid biosynthetic process GO:0046456 42 28 0,000 0,13465984 0,15809986 ! negative regulation of response to external stimulus GO:0032102 37 28 0,000 0,13465984 0,1580192 ! cell junction assembly GO:0034329 56 28 0,000 0,13465984 0,15793862 ! positive regulation of endocytosis GO:0045807 33 28 0,000 0,13465984 0,15785812 ! cholesterol homeostasis GO:0042632 46 28 0,000 0,13465984 0,1577777 GO:0055092|sterol homeostasis, ! GPI anchor metabolic process GO:0006505 40 28 0,000 0,13465984 0,15769737 ! complement activation, classical pathway GO:0006958 36 28 0,000 0,13465984 0,15761712 ! triglyceride metabolic process GO:0006641 34 28 0,000 0,13465984 0,15753695 ! erythrocyte differentiation GO:0030218 38 28 0,000 0,13465984 0,15745686 ! immune response-activating signal transduction GO:0002757 38 28 0,000 0,13465984 0,15737685 GO:0002764|immune response-regulating signal transduction, ! regulation of systemic arterial blood pressure GO:0003073 47 28 0,000 0,13465984 0,15729692 ! nuclear-transcribed mRNA catabolic process GO:0000956 38 28 0,000 0,13465984 0,15721707 ! mesoderm formation GO:0001707 46 28 0,000 0,13465984 0,15713731 ! positive regulation of multicellular organism growth GO:0040018 38 28 0,000 0,13465984 0,15705762 ! negative regulation of MAP kinase activity GO:0043407 54 28 0,000 0,13465984 0,15697802 ! sterol biosynthetic process GO:0016126 40 28 0,000 0,13465984 0,1568985 ! ensheathment of neurons GO:0007272 43 28 0,000 0,13465984 0,15681906 GO:0008366|axon ensheathment, ! BMP signaling pathway GO:0030509 40 28 0,000 0,13465984 0,15673969 ! myeloid leukocyte activation GO:0002274 39 28 0,000 0,13465984 0,15666041 ! placenta development GO:0001890 37 28 0,000 0,13465984 0,15658121 ! regulation of B cell activation GO:0050864 42 28 0,000 0,13465984 0,15650209 ! response to hydrogen peroxide GO:0042542 42 29 0,000 0,13912189 0,16160624 ! regulation of innate immune response GO:0045088 38 29 0,000 0,13912189 0,16152466 ! ovulation cycle process GO:0022602 41 29 0,000 0,13912189 0,16144316 ! positive regulation of T cell proliferation GO:0042102 44 29 0,000 0,13912189 0,16136175 ! protein targeting to membrane GO:0006612 53 29 0,000 0,13912189 0,16128042 ! mismatch repair GO:0006298 34 29 0,000 0,13912189 0,16119917 ! muscle cell development GO:0055001 38 29 0,000 0,13912189 0,161118 ! formation of primary germ layer GO:0001704 48 29 0,000 0,13912189 0,16103691 ! hexose biosynthetic process GO:0019319 35 29 0,000 0,13912189 0,16095591 ! eye morphogenesis GO:0048592 51 29 0,000 0,13912189 0,16087499 ! regulation of calcium ion transport GO:0051924 37 29 0,000 0,13912189 0,16079415 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 42 30 0,000 0,14356119 0,16584165 ! collagen metabolic process GO:0032963 40 30 0,000 0,14356119 0,1657584 ! organic anion transport GO:0015711 51 30 0,000 0,14356119 0,16567523 ! cholesterol transport GO:0030301 46 30 0,000 0,14356119 0,16559214 GO:0015918|sterol transport, ! spliceosome assembly GO:0000245 49 30 0,000 0,14356119 0,16550914 ! spindle organization GO:0007051 37 30 0,000 0,14356119 0,16542622 ! pigment biosynthetic process GO:0046148 50 30 0,000 0,14356119 0,16534338 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 39 30 0,000 0,14356119 0,16526063 ! positive regulation of neurogenesis GO:0050769 45 30 0,000 0,14356119 0,16517795 ! ceramide metabolic process GO:0006672 43 30 0,000 0,14356119 0,16509536 ! ovulation cycle GO:0042698 43 30 0,000 0,14356119 0,16501286 ! fatty acid catabolic process GO:0009062 43 30 0,000 0,14356119 0,16493043 ! adult locomotory behavior GO:0008344 47 30 0,000 0,14356119 0,16484809 ! negative regulation of cell activation GO:0050866 44 30 0,000 0,14356119 0,16476583 ! response to heat GO:0009408 41 30 0,000 0,14356119 0,16468366 ! positive regulation of immune effector process GO:0002699 40 30 0,000 0,14356119 0,16460156 ! establishment of vesicle localization GO:0051650 45 30 0,000 0,14356119 0,16451955 ! negative regulation of secretion GO:0051048 49 31 0,000 0,14797784 0,16949653 ! cellular component assembly involved in morphogenesis GO:0010927 43 31 0,000 0,14797784 0,16941217 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 37 31 0,000 0,14797784 0,16932788 ! odontogenesis GO:0042476 50 31 0,000 0,14797784 0,16924368 ! mesoderm morphogenesis GO:0048332 49 31 0,000 0,14797784 0,16915956 ! metanephros development GO:0001656 58 31 0,000 0,14797784 0,16907553 ! unsaturated fatty acid biosynthetic process GO:0006636 46 31 0,000 0,14797784 0,16899158 ! response to mechanical stimulus GO:0009612 43 31 0,000 0,14797784 0,16890771 ! cell fate specification GO:0001708 37 31 0,000 0,14797784 0,16882393 ! leukocyte chemotaxis GO:0030595 43 31 0,000 0,14797784 0,16874023 GO:0060326|cell chemotaxis, ! biogenic amine biosynthetic process GO:0042401 44 31 0,000 0,14797784 0,16865661 ! RNA modification GO:0009451 40 31 0,000 0,14797784 0,16857308 ! mitotic sister chromatid segregation GO:0000070 45 32 0,000 0,15237198 0,17349284 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 43 32 0,000 0,15237198 0,173407 ! regulation of synaptic plasticity GO:0048167 52 32 0,000 0,15237198 0,17332124 ! regulation of ARF protein signal transduction GO:0032012 51 32 0,000 0,15237198 0,17323556 ! neutral lipid metabolic process GO:0006638 41 32 0,000 0,15237198 0,17314997 GO:0006639|acylglycerol metabolic process, ! peripheral nervous system development GO:0007422 53 32 0,000 0,15237198 0,17306447 ! calcium-mediated signaling GO:0019722 50 32 0,000 0,15237198 0,17297904 ! cytokine production GO:0001816 44 32 0,000 0,15237198 0,17289371 ! monosaccharide biosynthetic process GO:0046364 38 32 0,000 0,15237198 0,17280845 ! symbiosis, encompassing mutualism through parasitism GO:0044403 47 32 0,000 0,15237198 0,17272328 ! vesicle localization GO:0051648 47 32 0,000 0,15237198 0,1726382 ! RNA export from nucleus GO:0006405 44 33 0,000 0,1567437 0,17750394 ! positive regulation of DNA metabolic process GO:0051054 54 33 0,000 0,1567437 0,17741658 ! phosphoinositide biosynthetic process GO:0046489 47 33 0,000 0,1567437 0,17732932 ! ER to Golgi vesicle-mediated transport GO:0006888 53 33 0,000 0,1567437 0,17724213 ! negative regulation of cell adhesion GO:0007162 67 33 0,000 0,1567437 0,17715504 ! sister chromatid segregation GO:0000819 46 33 0,000 0,1567437 0,17706803 ! ear morphogenesis GO:0042471 42 33 0,000 0,1567437 0,1769811 ! actomyosin structure organization GO:0031032 43 33 0,000 0,1567437 0,17689426 ! cell junction organization GO:0034330 63 33 0,000 0,1567437 0,1768075 ! antigen processing and presentation of peptide antigen GO:0048002 58 33 0,000 0,1567437 0,17672083 ! sphingoid metabolic process GO:0046519 47 33 0,000 0,1567437 0,17663425 ! carbohydrate homeostasis GO:0033500 39 33 0,000 0,1567437 0,17654775 GO:0042593|glucose homeostasis, ! nucleus organization GO:0006997 49 33 0,000 0,1567437 0,17646133 ! multicellular organismal macromolecule metabolic process GO:0044259 44 33 0,000 0,1567437 0,176375 ! positive regulation of cell development GO:0010720 54 33 0,000 0,1567437 0,17628875 ! lipid homeostasis GO:0055088 55 33 0,000 0,1567437 0,17620259 ! nucleotide catabolic process GO:0009166 46 33 0,000 0,1567437 0,17611651 ! regulation of proteolysis GO:0030162 50 33 0,000 0,1567437 0,17603052 ! hormone biosynthetic process GO:0042446 45 33 0,000 0,1567437 0,17594461 ! pyrimidine nucleotide metabolic process GO:0006220 45 33 0,000 0,1567437 0,17585878 ! mRNA catabolic process GO:0006402 48 34 0,000 0,16109312 0,1806505 ! positive regulation of JAK-STAT cascade GO:0046427 45 34 0,000 0,16109312 0,18056246 ! establishment or maintenance of cell polarity GO:0007163 61 34 0,000 0,16109312 0,18047451 ! feeding behavior GO:0007631 45 34 0,000 0,16109312 0,18038665 ! development of primary male sexual characteristics GO:0046546 44 34 0,000 0,16109312 0,18029887 ! glycerol ether metabolic process GO:0006662 44 34 0,000 0,16109312 0,18021117 ! erythrocyte homeostasis GO:0034101 45 34 0,000 0,16109312 0,18012356 ! regulation of Wnt receptor signaling pathway GO:0030111 52 34 0,000 0,16109312 0,18003604 ! isoprenoid metabolic process GO:0006720 46 34 0,000 0,16109312 0,1799486 ! polyol metabolic process GO:0019751 44 34 0,000 0,16109312 0,17986125 ! aerobic respiration GO:0009060 47 34 0,000 0,16109312 0,17977398 ! embryonic organ development GO:0048568 45 34 0,000 0,16109312 0,17968679 ! regulation of metal ion transport GO:0010959 47 35 0,000 0,16542035 0,18442405 ! Notch signaling pathway GO:0007219 56 35 0,000 0,16542035 0,1843347 ! polysaccharide biosynthetic process GO:0000271 47 35 0,000 0,16542035 0,18424543 ! regulation of Rab protein signal transduction GO:0032483 52 35 0,000 0,16542035 0,18415625 GO:0032313|regulation of Rab GTPase activity, ! keratinocyte differentiation GO:0030216 47 35 0,000 0,16542035 0,18406716 ! cyclic nucleotide metabolic process GO:0009187 58 35 0,000 0,16542035 0,18397815 ! regulation of action potential in neuron GO:0019228 54 35 0,000 0,16542035 0,18388923 ! energy coupled proton transport, down electrochemical gradient GO:0015985 53 35 0,000 0,16542035 0,18380039 GO:0015986|ATP synthesis coupled proton transport, ! Rho protein signal transduction GO:0007266 51 35 0,000 0,16542035 0,18371164 ! pigment metabolic process GO:0042440 61 35 0,000 0,16542035 0,18362298 ! positive regulation of leukocyte proliferation GO:0070665 50 35 0,000 0,16542035 0,1835344 GO:0070668|positive regulation of mast cell proliferation, GO:0050671|positive regulation of lymphocyte proliferation, GO:0032946|positive regulation of mononuclear cell proliferation, ! response to reactive oxygen species GO:0000302 55 36 0,000 0,16972552 0,1882202 ! regulation of hormone secretion GO:0046883 48 36 0,000 0,16972552 0,18812949 ! organic ether metabolic process GO:0018904 46 36 0,000 0,16972552 0,18803887 ! hormone-mediated signaling GO:0009755 49 36 0,000 0,16972552 0,18794833 ! heterocycle biosynthetic process GO:0018130 46 36 0,000 0,16972552 0,18785789 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 54 37 0,000 0,17400872 0,19250604 ! activation of plasma proteins involved in acute inflammatory response GO:0002541 45 37 0,000 0,17400872 0,19241348 GO:0006956|complement activation, ! protein amino acid N-linked glycosylation GO:0006487 49 37 0,000 0,17400872 0,19232102 ! learning GO:0007612 67 37 0,000 0,17400872 0,19222865 ! ion transmembrane transport GO:0034220 56 37 0,000 0,17400872 0,19213636 ! ribonucleoside metabolic process GO:0009119 48 37 0,000 0,17400872 0,19204417 ! regulation of protein secretion GO:0050708 51 37 0,000 0,17400872 0,19195206 ! transforming growth factor beta receptor signaling pathway GO:0007179 51 38 0,000 0,17827006 0,19655856 ! striated muscle cell differentiation GO:0051146 54 38 0,000 0,17827006 0,19646437 ! monocarboxylic acid transport GO:0015718 62 38 0,000 0,17827006 0,19637028 ! alcohol biosynthetic process GO:0046165 45 38 0,000 0,17827006 0,19627628 ! regulation of T cell proliferation GO:0042129 58 38 0,000 0,17827006 0,19618237 ! phagocytosis GO:0006909 60 38 0,000 0,17827006 0,19608855 ! mesenchymal cell development GO:0014031 64 38 0,000 0,17827006 0,19599481 GO:0048762|mesenchymal cell differentiation, GO:0060485|mesenchyme development, ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 63 39 0,000 0,18250967 0,20056008 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 62 39 0,000 0,18250967 0,2004643 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 63 39 0,000 0,18250967 0,20036861 ! multicellular organismal metabolic process GO:0044236 50 39 0,000 0,18250967 0,20027302 ! male sex differentiation GO:0046661 53 39 0,000 0,18250967 0,20017751 ! regulation of lymphocyte mediated immunity GO:0002706 60 39 0,000 0,18250967 0,2000821 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 49 39 0,000 0,18250967 0,19998678 ! JNK cascade GO:0007254 54 39 0,000 0,18250967 0,19989154 ! synapse organization GO:0050808 55 39 0,000 0,18250967 0,1997964 ! response to calcium ion GO:0051592 58 40 0,000 0,18672765 0,20431664 ! stress-activated protein kinase signaling pathway GO:0031098 55 40 0,000 0,18672765 0,20421949 ! regulation of tube size GO:0035150 60 40 0,000 0,18672765 0,20412243 GO:0050880|regulation of blood vessel size, ! detection of stimulus involved in sensory perception GO:0050906 50 40 0,000 0,18672765 0,20402546 ! peptide metabolic process GO:0006518 56 40 0,000 0,18672765 0,20392858 ! inner ear development GO:0048839 57 40 0,000 0,18672765 0,20383179 ! ATP synthesis coupled electron transport GO:0042773 48 40 0,000 0,18672765 0,2037351 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! epidermal cell differentiation GO:0009913 53 40 0,000 0,18672765 0,20363849 ! regulation of myeloid cell differentiation GO:0045637 69 40 0,000 0,18672765 0,20354198 ! epithelial cell differentiation GO:0030855 55 41 0,000 0,1909241 0,20801773 ! protein amino acid lipidation GO:0006497 62 41 0,000 0,1909241 0,20791923 ! glucose transport GO:0015758 52 41 0,000 0,1909241 0,20782083 ! striated muscle contraction GO:0006941 62 41 0,000 0,1909241 0,20772253 ! regulation of leukocyte mediated immunity GO:0002703 62 41 0,000 0,1909241 0,20762431 ! biopolymer methylation GO:0043414 62 41 0,000 0,1909241 0,20752619 ! regulation of JNK cascade GO:0046328 58 41 0,000 0,1909241 0,20742816 ! receptor-mediated endocytosis GO:0006898 76 42 0,000 0,19509913 0,21186403 ! regulation of JAK-STAT cascade GO:0046425 61 42 0,000 0,19509913 0,21176404 ! cellular component disassembly GO:0022411 64 42 0,000 0,19509913 0,21166416 ! regulation of stress-activated protein kinase signaling pathway GO:0070302 61 42 0,000 0,19509913 0,21156436 ! hexose transport GO:0008645 54 42 0,000 0,19509913 0,21146466 GO:0015749|monosaccharide transport, ! excretion GO:0007588 63 42 0,000 0,19509913 0,21136505 ! glycosaminoglycan metabolic process GO:0030203 63 42 0,000 0,19509913 0,21126554 ! icosanoid metabolic process GO:0006690 61 42 0,000 0,19509913 0,21116612 ! regulation of gene expression, epigenetic GO:0040029 72 42 0,000 0,19509913 0,2110668 ! leukocyte migration GO:0050900 60 43 0,000 0,19925287 0,21545914 ! neuromuscular process GO:0050905 79 43 0,000 0,19925287 0,21535789 ! tRNA processing GO:0008033 49 43 0,000 0,19925287 0,21525674 ! vesicle organization GO:0016050 79 43 0,000 0,19925287 0,21515568 ! methylation GO:0032259 64 43 0,000 0,19925287 0,21505471 ! activation of adenylate cyclase activity GO:0007190 76 44 0,000 0,2033854 0,21941202 ! glycolysis GO:0006096 53 44 0,000 0,2033854 0,21930915 ! regulation of action potential GO:0001508 71 44 0,000 0,2033854 0,21920638 ! regulation of ion transport GO:0043269 57 44 0,000 0,2033854 0,21910371 ! cellular amino acid biosynthetic process GO:0008652 51 44 0,000 0,2033854 0,21900113 ! induction of apoptosis by extracellular signals GO:0008624 74 44 0,000 0,2033854 0,21889865 ! generation of a signal involved in cell-cell signaling GO:0003001 62 44 0,000 0,2033854 0,21879627 ! ribonucleoprotein complex assembly GO:0022618 70 44 0,000 0,2033854 0,21869398 ! regulation of inflammatory response GO:0050727 60 44 0,000 0,2033854 0,21859178 ! detection of abiotic stimulus GO:0009582 58 44 0,000 0,2033854 0,21848969 ! regulation of mast cell proliferation GO:0070666 64 44 0,000 0,2033854 0,21838768 ! RNA catabolic process GO:0006401 64 45 0,000 0,20749684 0,22269843 ! positive regulation of defense response GO:0031349 59 45 0,000 0,20749684 0,22259456 ! lipoprotein biosynthetic process GO:0042158 67 45 0,000 0,20749684 0,22249078 ! positive regulation of adenylate cyclase activity GO:0045762 86 46 0,000 0,2115873 0,2267711 ! cell redox homeostasis GO:0045454 63 46 0,000 0,2115873 0,22666548 ! unsaturated fatty acid metabolic process GO:0033559 66 46 0,000 0,2115873 0,22655995 ! regulation of ossification GO:0030278 71 46 0,000 0,2115873 0,22645453 ! respiratory electron transport chain GO:0022904 59 47 0,000 0,21565687 0,2307027 ! endocrine system development GO:0035270 83 47 0,000 0,21565687 0,23059545 ! RNA elongation from RNA polymerase II promoter GO:0006368 60 47 0,000 0,21565687 0,23048829 ! positive regulation of cyclase activity GO:0031281 87 47 0,000 0,21565687 0,23038124 ! negative regulation of immune system process GO:0002683 73 47 0,000 0,21565687 0,23027428 ! glutamine family amino acid metabolic process GO:0009064 59 47 0,000 0,21565687 0,23016743 ! regulation of leukocyte proliferation GO:0070663 71 47 0,000 0,21565687 0,23006067 GO:0050670|regulation of lymphocyte proliferation, GO:0032944|regulation of mononuclear cell proliferation, ! chloride transport GO:0006821 67 48 0,000 0,21970568 0,23427124 ! regulation of muscle contraction GO:0006937 69 48 0,000 0,21970568 0,23416268 ! response to temperature stimulus GO:0009266 62 48 0,000 0,21970568 0,23405422 ! gastrulation GO:0007369 73 48 0,000 0,21970568 0,23394586 ! heart morphogenesis GO:0003007 65 48 0,000 0,21970568 0,2338376 ! immunoglobulin mediated immune response GO:0016064 66 48 0,000 0,21970568 0,23372944 GO:0019724|B cell mediated immunity, ! positive regulation of lyase activity GO:0051349 88 48 0,000 0,21970568 0,23362139 ! regulation of endocytosis GO:0030100 63 48 0,000 0,21970568 0,23351343 ! nuclear export GO:0051168 69 48 0,000 0,21970568 0,23340557 ! positive regulation of cytokine production GO:0001819 73 48 0,000 0,21970568 0,23329781 ! aminoglycan metabolic process GO:0006022 72 49 0,000 0,22373381 0,23746551 ! sensory perception of smell GO:0007608 61 49 0,000 0,22373381 0,23735598 ! sulfur compound biosynthetic process GO:0044272 62 49 0,000 0,22373381 0,23724655 ! nucleoside monophosphate biosynthetic process GO:0009124 73 49 0,000 0,22373381 0,23713722 ! RNA elongation GO:0006354 62 49 0,000 0,22373381 0,23702799 ! cartilage development GO:0051216 70 49 0,000 0,22373381 0,23691886 ! ear development GO:0043583 72 50 0,000 0,22774138 0,24105162 ! positive regulation of growth GO:0045927 67 50 0,000 0,22774138 0,24094074 ! regulation of multicellular organism growth GO:0040014 65 50 0,000 0,22774138 0,24082997 ! proton transport GO:0015992 75 50 0,000 0,22774138 0,24071929 ! cellular amino acid derivative biosynthetic process GO:0042398 68 50 0,000 0,22774138 0,24060872 ! positive regulation of secretion GO:0051047 71 51 0,000 0,23172849 0,24470869 ! hydrogen transport GO:0006818 77 51 0,000 0,23172849 0,24459639 ! activation of phospholipase C activity GO:0007202 87 51 0,000 0,23172849 0,24448419 GO:0010863|positive regulation of phospholipase C activity, ! positive regulation of organelle organization GO:0010638 82 51 0,000 0,23172849 0,24437209 ! adult behavior GO:0030534 80 51 0,000 0,23172849 0,24426009 ! transition metal ion transport GO:0000041 74 52 0,000 0,23569524 0,24832755 ! positive regulation of phospholipase activity GO:0010518 88 52 0,000 0,23569524 0,24821385 ! sphingolipid metabolic process GO:0006665 72 52 0,000 0,23569524 0,24810025 ! establishment of organelle localization GO:0051656 85 52 0,000 0,23569524 0,24798676 ! glycerophospholipid biosynthetic process GO:0046474 75 53 0,000 0,23964174 0,25202377 ! regulation of neurotransmitter levels GO:0001505 73 53 0,000 0,23964174 0,25190859 ! kidney development GO:0001822 90 53 0,000 0,23964174 0,25179351 ! single fertilization GO:0007338 59 53 0,000 0,23964174 0,25167854 ! cell projection assembly GO:0030031 76 53 0,000 0,23964174 0,25156367 ! amino acid transport GO:0006865 84 54 0,000 0,24356808 0,2555687 ! regulation of mitosis GO:0007088 84 54 0,000 0,24356808 0,25545216 GO:0051783|regulation of nuclear division, ! glucose catabolic process GO:0006007 66 54 0,000 0,24356808 0,25533573 ! regulation of phospholipase activity GO:0010517 90 54 0,000 0,24356808 0,2552194 ! DNA catabolic process GO:0006308 67 54 0,000 0,24356808 0,25510318 ! positive regulation of lipase activity GO:0060193 90 54 0,000 0,24356808 0,25498707 ! exocytosis GO:0006887 74 55 0,000 0,24747437 0,25895862 ! nucleoside metabolic process GO:0009116 69 55 0,000 0,24747437 0,25884086 ! regulation of lipid metabolic process GO:0019216 84 56 0,000 0,25136072 0,2627862 ! negative regulation of response to stimulus GO:0048585 80 56 0,000 0,25136072 0,26266681 ! carbohydrate transport GO:0008643 74 57 0,000 0,25522721 0,2665861 ! multicellular organism reproduction GO:0032504 83 57 0,000 0,25522721 0,26646509 GO:0048609|reproductive process in a multicellular organism, ! chromosome segregation GO:0007059 83 57 0,000 0,25522721 0,26634419 ! membrane lipid metabolic process GO:0006643 79 57 0,000 0,25522721 0,26622339 ! camera-type eye development GO:0043010 88 57 0,000 0,25522721 0,26610271 ! protein maturation by peptide bond cleavage GO:0051605 76 58 0,000 0,25907396 0,26999098 ! oxygen and reactive oxygen species metabolic process GO:0006800 77 59 0,000 0,26290105 0,27385526 ! activation of MAPK activity GO:0000187 84 59 0,000 0,26290105 0,27373129 ! nucleoside monophosphate metabolic process GO:0009123 95 59 0,000 0,26290105 0,27360743 ! myeloid cell differentiation GO:0030099 85 59 0,000 0,26290105 0,27348368 ! glycerolipid biosynthetic process GO:0045017 85 60 0,000 0,2667086 0,27731907 ! regulation of heart contraction GO:0008016 91 60 0,000 0,2667086 0,27719376 ! regulation of vesicle-mediated transport GO:0060627 79 60 0,000 0,2667086 0,27706856 ! fertilization GO:0009566 68 60 0,000 0,2667086 0,27694347 ! regulation of cellular response to stress GO:0080135 85 61 0,000 0,2704967 0,28075018 ! lipoprotein metabolic process GO:0042157 89 61 0,000 0,2704967 0,28062355 ! urogenital system development GO:0001655 101 61 0,000 0,2704967 0,28049703 ! homeostasis of number of cells GO:0048872 84 61 0,000 0,2704967 0,28037062 ! fatty acid biosynthetic process GO:0006633 92 61 0,000 0,2704967 0,28024433 ! extracellular matrix organization GO:0030198 103 61 0,000 0,2704967 0,28011815 ! neurotransmitter transport GO:0006836 81 62 0,000 0,27426544 0,28389312 ! cellular hormone metabolic process GO:0034754 87 62 0,000 0,27426544 0,28376542 ! lymphocyte mediated immunity GO:0002449 88 62 0,000 0,27426544 0,28363782 ! organelle localization GO:0051640 96 62 0,000 0,27426544 0,28351035 ! regulation of lipase activity GO:0060191 109 63 0,000 0,27801493 0,28725712 ! neuropeptide signaling pathway GO:0007218 79 64 0,000 0,28174526 0,29098074 ! hexose catabolic process GO:0019320 82 64 0,000 0,28174526 0,29085014 ! defense response to bacterium GO:0042742 73 65 0,000 0,28545654 0,29454914 ! regulation of MAPKKK cascade GO:0043408 101 65 0,000 0,28545654 0,29441706 ! activation of immune response GO:0002253 83 65 0,000 0,28545654 0,29428509 ! antigen processing and presentation GO:0019882 96 66 0,000 0,28914884 0,29795804 ! regulation of Rho protein signal transduction GO:0035023 111 66 0,000 0,28914884 0,2978246 ! regulation of immune effector process GO:0002697 101 66 0,000 0,28914884 0,29769129 ! elevation of cytosolic calcium ion concentration GO:0007204 105 67 0,000 0,29282228 0,30133837 ! acute inflammatory response GO:0002526 92 68 0,000 0,29647695 0,30496287 ! cytosolic calcium ion homeostasis GO:0051480 107 68 0,000 0,29647695 0,30482654 ! regulation of Ras GTPase activity GO:0032318 110 68 0,000 0,29647695 0,30469034 ! rhythmic process GO:0048511 105 68 0,000 0,29647695 0,30455426 ! inorganic anion transport GO:0015698 93 68 0,000 0,29647695 0,30441829 ! sensory perception of chemical stimulus GO:0007606 85 69 0,000 0,30011293 0,30801417 ! activation of protein kinase activity GO:0032147 102 69 0,000 0,30011293 0,30787678 ! response to metal ion GO:0010038 103 70 0,000 0,30373034 0,31144885 ! humoral immune response GO:0006959 86 70 0,000 0,30373034 0,31131006 ! eye development GO:0001654 111 70 0,000 0,30373034 0,31117139 ! amine transport GO:0015837 101 70 0,000 0,30373034 0,31103285 ! transcription initiation from RNA polymerase II promoter GO:0006367 91 70 0,000 0,30373034 0,31089443 ! phosphoinositide-mediated signaling GO:0048015 109 71 0,000 0,30732925 0,31443829 ! leukocyte mediated immunity GO:0002443 99 71 0,000 0,30732925 0,31429848 ! monosaccharide catabolic process GO:0046365 91 71 0,000 0,30732925 0,31415879 ! regulation of synaptic transmission GO:0050804 109 72 0,000 0,31090977 0,31767768 ! regulation of blood pressure GO:0008217 107 73 0,000 0,31447198 0,32117476 ! cellular lipid catabolic process GO:0044242 105 73 0,000 0,31447198 0,3210322 ! phospholipid biosynthetic process GO:0008654 102 74 0,000 0,31801598 0,3245061 ! digestion GO:0007586 97 74 0,000 0,31801598 0,3243622 ! blood coagulation GO:0007596 116 75 0,000 0,32154186 0,32781307 GO:0050817|coagulation, ! response to inorganic substance GO:0010035 115 75 0,000 0,32154186 0,32766783 ! amine biosynthetic process GO:0009309 97 76 0,000 0,32504972 0,33109581 ! cholesterol metabolic process GO:0008203 109 77 0,000 0,32853964 0,33450251 ! one-carbon metabolic process GO:0006730 110 77 0,000 0,32853964 0,3343545 ! regulation of transmission of nerve impulse GO:0051969 116 77 0,000 0,32853964 0,33420662 ! carbohydrate biosynthetic process GO:0016051 97 77 0,000 0,32853964 0,33405887 ! cellular respiration GO:0045333 107 79 0,000 0,33546603 0,34095089 ! oxidative phosphorylation GO:0006119 105 79 0,000 0,33546603 0,34080029 ! ATP biosynthetic process GO:0006754 118 79 0,000 0,33546603 0,34064983 ! chromatin assembly GO:0031497 102 80 0,000 0,33890268 0,34398771 GO:0006334|nucleosome assembly, ! alcohol catabolic process GO:0046164 104 80 0,000 0,33890268 0,34383598 ! regulation of GTPase activity GO:0043087 129 80 0,000 0,33890268 0,34368437 ! hemostasis GO:0007599 125 81 0,000 0,34232175 0,34699869 ! regulation of neurological system process GO:0031644 122 81 0,000 0,34232175 0,34684583 ! ossification GO:0001503 134 82 0,000 0,34572334 0,35013813 GO:0060348|bone development, ! regulation of cell adhesion GO:0030155 159 83 0,000 0,34910753 0,35340991 ! regulation of defense response GO:0031347 117 84 0,000 0,35247441 0,35666131 ! protein-DNA complex assembly GO:0065004 107 84 0,000 0,35247441 0,35650446 ! sterol metabolic process GO:0016125 120 84 0,000 0,35247441 0,35634776 ! Golgi vesicle transport GO:0048193 138 85 0,000 0,35582407 0,35957617 ! rRNA metabolic process GO:0016072 107 85 0,000 0,35582407 0,35941825 GO:0006364|rRNA processing, ! transcription initiation GO:0006352 118 85 0,000 0,35582407 0,35926047 ! regulation of membrane potential GO:0042391 128 85 0,000 0,35582407 0,35910283 ! nucleosome organization GO:0034728 114 87 0,000 0,36247206 0,36565164 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 126 87 0,000 0,36247206 0,36549133 GO:0009145|purine nucleoside triphosphate biosynthetic process, ! cellular defense response GO:0006968 102 87 0,000 0,36247206 0,36533117 ! female pregnancy GO:0007565 130 87 0,000 0,36247206 0,36517115 ! ribonucleoside triphosphate biosynthetic process GO:0009201 127 88 0,000 0,36577056 0,36833288 ! protein processing GO:0016485 114 88 0,000 0,36577056 0,36817168 ! nucleoside triphosphate biosynthetic process GO:0009142 128 89 0,000 0,36905219 0,37131235 ! hormone metabolic process GO:0042445 121 90 0,000 0,37231703 0,37443339 ! ATP metabolic process GO:0046034 137 91 0,000 0,37556516 0,3775349 ! positive regulation of immune response GO:0050778 121 92 0,000 0,37879666 0,38061701 ! sulfur metabolic process GO:0006790 118 92 0,000 0,37879666 0,3804508 ! carbohydrate catabolic process GO:0016052 121 93 0,000 0,38201163 0,38351233 ! response to oxidative stress GO:0006979 141 94 0,000 0,38521015 0,38655468 ! carboxylic acid transport GO:0046942 147 95 0,000 0,38839229 0,38957796 GO:0015849|organic acid transport, ! protein maturation GO:0051604 129 96 0,000 0,39155814 0,39258227 ! protein amino acid glycosylation GO:0006486 134 97 0,000 0,39470779 0,39556772 GO:0043413|biopolymer glycosylation, GO:0070085|glycosylation, ! calcium ion transport GO:0006816 167 99 0,000 0,40095879 0,40165733 ! extracellular structure organization GO:0043062 156 99 0,000 0,40095879 0,40148246 ! purine ribonucleoside triphosphate metabolic process GO:0009205 146 100 0,000 0,40406031 0,40441197 ! divalent metal ion transport GO:0070838 171 100 0,000 0,40406031 0,40423607 ! regulation of body fluid levels GO:0050878 154 100 0,000 0,40406031 0,40406031